FedInvent™ Patents
Patent Details for Tuesday, October 04, 2016
This page was updated on Monday, March 27, 2023 at 04:52 AM GMT
Department of Health and Human Services (HHS)
US 09456588 | Chan et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | David C. Chan (Arcadia, California); Anh H. Pham (Pasadena, California) |
ABSTRACT | An animal model for Parkinson's disease has a disrupted Mfn2 gene in dopaminergic neurons. The Mfn2 gene disruption results in severe movement disorder attributed to progressive degeneration of the nigrostriatal circuit as found in Parkinson's disease. The animal model having exogenous suppression of the Mfn2 gene in dopaminergic neurons is a suitable animal model for studying Parkinson's disease. |
FILED | Friday, June 21, 2013 |
APPL NO | 13/924490 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 67/0276 (20130101) A01K 2217/075 (20130101) A01K 2217/206 (20130101) A01K 2227/105 (20130101) A01K 2267/0318 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09456773 | Benni |
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FUNDED BY |
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APPLICANT(S) | CAS Medical Systems, Inc. (Branford, Connecticut) |
ASSIGNEE(S) | CAS Medical Systems, Inc. (Branford, Connecticut) |
INVENTOR(S) | Paul B. Benni (Acton, Massachusetts) |
ABSTRACT | According to the present invention, a method and apparatus for non-invasively determining the blood oxygen saturation level within a subject's tissue is provided. The method comprises the steps of: a) providing a spectrophotometric sensor operable to transmit light into the subject's tissue, and to sense the light; b) detecting light after passage through the subject's tissue using the sensor, and producing initial signal data from the light sensed; c) calibrating the sensor to that particular subject using the initial signal data, thereby accounting for the specific physical characteristics of the particular subject's tissue being sensed; and d) using the calibrated sensor to determine the blood oxygen parameter value within the subject's tissue. |
FILED | Thursday, November 20, 2014 |
APPL NO | 14/549135 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0205 (20130101) A61B 5/0261 (20130101) A61B 5/1495 (20130101) A61B 5/6814 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) Original (OR) Class A61B 5/14552 (20130101) A61B 5/14553 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/49 (20130101) G01N 21/359 (20130101) G01N 2021/3144 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09456794 | Carpenter et al. |
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FUNDED BY |
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APPLICANT(S) | Colin M Carpenter (Redwood City, California); Lei Xing (Palo Alto, California); Guillem Pratx (Mountain View, California); Conroy Ghin Chee Sun (Sunnyvale, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Colin M Carpenter (Redwood City, California); Lei Xing (Palo Alto, California); Guillem Pratx (Mountain View, California); Conroy Ghin Chee Sun (Sunnyvale, California) |
ABSTRACT | Molecular imaging of radioluminescent nanoparticle probes injected into biological tissue is performed by irradiated the tissue with ionizing radiation to induce radioluminescence at optical wavelengths, preferably at predetermined near infrared wavelengths. The optical light is detected and processed to determine a spatial distribution of the probes. The radioluminescent nanoparticles may be inorganic or organic phosphors, scintillators, or quantum dots. Imaging systems realizing this technique include tomographic systems using an x-ray beam to sequentially irradiate selected regions, systems with a radioactive source producing the ionizing radiation from outside the tissue, such as with a beam, or inside the tissue, such as with an endoscope or injected radiopharmaceutical. The optical signals may be detected by a photodetector array external to the tissue, a photodetector integrated with an endoscope or mammographic paddle, integrated into a capsule endoscope, or an array positioned near the biological tissue. |
FILED | Friday, April 08, 2011 |
APPL NO | 13/066190 |
ART UNIT | 3777 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/425 (20130101) A61B 6/508 (20130101) A61B 6/4057 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09456835 | Zhong et al. |
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FUNDED BY |
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APPLICANT(S) | Pei Zhong (Chapel Hill, North Carolina); Walter Neal Simmons (Durham, North Carolina); Georgy N. Sankin (Durham, North Carolina); Nathan Smith (Durham, North Carolina); Franklin Hadley Cocks (Durham, North Carolina); Glenn M. Preminger (Chapel Hill, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Pei Zhong (Chapel Hill, North Carolina); Walter Neal Simmons (Durham, North Carolina); Georgy N. Sankin (Durham, North Carolina); Nathan Smith (Durham, North Carolina); Franklin Hadley Cocks (Durham, North Carolina); Glenn M. Preminger (Chapel Hill, North Carolina) |
ABSTRACT | Lithotripter apparatuses and methods are provided for selectively modifying an acoustic pressure field and can include a shock wave source operable to generate a shock wave having a substantially axisymmetric acoustic pressure field, an acoustic focusing member positioned between the shock wave source and a target, and an acoustic barrier positioned between the shock wave source and the acoustic focusing member. The acoustic barrier can be operable to selectively block a portion of the shock wave generated by the shock wave source such that the substantially axisymmetric pressure field is transformed into a modified acoustic pressure field. |
FILED | Friday, March 23, 2012 |
APPL NO | 13/428937 |
ART UNIT | 3777 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/225 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09456923 | Keller |
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FUNDED BY |
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APPLICANT(S) | MYNOSYS CELLULAR DEVICES, INC. (Fremont, California) |
ASSIGNEE(S) | Mynosys Cellular Devices, Inc. (Fremont, California) |
INVENTOR(S) | Christopher Guild Keller (El Cerrito, California) |
ABSTRACT | A surgical device and procedure are provided for smoothly and easily accessing tissue to perform microsurgery, including a capsulotomy of a lens capsule of an eye. The device includes a handpiece with a tip for insertion into an incision in the cornea of the eye. A sliding element is disposed within the handpiece and a suction cup is mounted to the sliding element. The sliding element can be translated to move the suction cup into and out of the handpiece. A compression mechanism associated with the suction cup and the handpiece compresses the suction cup for deployment through the tip of the handpiece. The suction cup can expand inside the anterior chamber into a cutting position on the lens capsule. A cutting element mounted to the suction cup is used to cut a portion of the lens capsule and to remove the portion from the eye. |
FILED | Wednesday, June 10, 2015 |
APPL NO | 14/736209 |
ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/32 (20130101) A61B 18/08 (20130101) A61B 2018/00291 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00754 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09456997 | Stauffer et al. |
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FUNDED BY |
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APPLICANT(S) | Brian Stauffer (Aurora, Colorado); Carmen Sucharov (Aurora, Colorado); Shelley Miyamoto (Aurora, Colorado) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
INVENTOR(S) | Brian Stauffer (Aurora, Colorado); Carmen Sucharov (Aurora, Colorado); Shelley Miyamoto (Aurora, Colorado) |
ABSTRACT | Provided are methods of treating heart failure in children using B1-selective adrenergic receptor antagonists, alone or in combination with other agents, including B-2-selective adrenergic receptor agonists. |
FILED | Thursday, August 25, 2011 |
APPL NO | 13/817969 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 31/138 (20130101) A61K 31/165 (20130101) A61K 31/352 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457040 | Cheng |
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FUNDED BY |
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APPLICANT(S) | University of South Florida (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Jin Q. Cheng (Tampa, Florida) |
ABSTRACT | The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat esophogeal adenocarcinoma by one or a combination of (i) administering triciribine only to patients which according to a diagnostic test described below, exhibit enhanced sensitivity to the drug; (ii) use of a described dosage level that minimizes the toxicity of the drug but yet still exhibits efficacy; or (iii) use of a described dosage regimen that minimizes the toxicity of the drug. |
FILED | Friday, August 21, 2015 |
APPL NO | 14/832400 |
ART UNIT | 1672 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/70 (20130101) A61K 31/7042 (20130101) A61K 31/7052 (20130101) A61K 31/7064 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/23 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 2333/912 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457041 | Kulkarni et al. |
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FUNDED BY |
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APPLICANT(S) | Prajakta S. Kulkarni (Fargo, North Dakota); Manas K. Haldar (Fargo, North Dakota); Sanku Mallik (West Fargo, North Dakota); D. K. Srivastava (Reilies Acres, North Dakota) |
ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
INVENTOR(S) | Prajakta S. Kulkarni (Fargo, North Dakota); Manas K. Haldar (Fargo, North Dakota); Sanku Mallik (West Fargo, North Dakota); D. K. Srivastava (Reilies Acres, North Dakota) |
ABSTRACT | Provided herein are nanoparticles that include a lipid layer and a compartment surrounded by the lipid layer. The lipid layer may include a lipid and a lipoprotein. The lipid may include a POPE lipid covalently attached to a hydrophilic polymer by a disulfide bond. The lipoprotein may include a trigger protein. The concentration of the first lipid may be between 1 mol % and 30 mol %. The disulfide bond of the first lipid is stable under conditions that include 10% human serum and is broken under conditions that include 50 micromolar glutathione. The hydrophilic polymer may include a PEG molecule. The trigger protein may include an amino acid repeat region, such as (GPX)n. The trigger protein may include a peptide bond that is cleaved by a gelatinase (e.g., gelatinase-B protease), or a member of the ADAM family of proteases (e.g., ADAM10 protease). Also provided are methods of using the nanoparticles. |
FILED | Friday, June 19, 2015 |
APPL NO | 14/744705 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1271 (20130101) A61K 31/7068 (20130101) Original (OR) Class A61K 49/0093 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457047 | Rubin-Bejerano et al. |
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FUNDED BY |
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APPLICANT(S) | Whitehead Institute (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); Boston University (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | Whitehead Institute (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Ifat Rubin-Bejerano (Belmont, Massachusetts); Gerald R. Fink (Chestnut Hill, Massachusetts); Claudia Abeijon (Worcester, Massachusetts); Daniel S. Kohane (Newton, Massachusetts); Jason E Fuller (Boston, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
ABSTRACT | This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety. |
FILED | Thursday, September 26, 2013 |
APPL NO | 14/037420 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/716 (20130101) Original (OR) Class A61K 36/09 (20130101) A61K 36/064 (20130101) A61K 45/06 (20130101) A61K 47/4823 (20130101) A61K 47/48538 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0024 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/126 (20130101) C08J 3/128 (20130101) C08J 2300/16 (20130101) C08J 2325/06 (20130101) C08J 2367/04 (20130101) C08J 2400/16 (20130101) C08J 2405/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457057 | Tompkins et al. |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Ronald G. Tompkins (Boston, Massachusetts); A. Aria Tzika (Jamaica Plain, Massachusetts); Yong-Ming Yu (Cambridge, Massachusetts); Laurence Rahme (Jamaica Plain, Massachusetts); Jeevendra A. Martyn (Winchester, Massachusetts) |
ABSTRACT | The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury. |
FILED | Wednesday, October 23, 2013 |
APPL NO | 14/061370 |
ART UNIT | 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/07 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457079 | Talchai et al. |
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FUNDED BY |
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APPLICANT(S) | Chutima Talchai (New York, New York); Domenico Accili (New York, New York) |
ASSIGNEE(S) | The Trustees Of Columbia University In The City Of New York (New York, New York) |
INVENTOR(S) | Chutima Talchai (New York, New York); Domenico Accili (New York, New York) |
ABSTRACT | Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more Foxo proteins or biologically active fragments or variants thereof. |
FILED | Thursday, May 12, 2011 |
APPL NO | 13/697792 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 39/3955 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 2333/62 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457080 | Freeman et al. |
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APPLICANT(S) | Emory University (Atlanta, Georgia); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Brigham and Women's Hospital (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Brigham and Women's Hospital, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Gordon Freeman (Brookline, Massachusetts); Arlene Sharpe (Brookline, Massachusetts); David M. Dorfman (Brookline, Massachusetts); Rafi Ahmed (Atlanta, Georgia); Daniel Barber (Rockville, Maryland); E. John Wherry (Havertown, Pennsylvania) |
ABSTRACT | The present invention provides methods and compositions for the treatment, prevention, or reduction of persistent infections, such as chronic infections, latent infections, and slow infections and cancer. The methods and compositions of the invention are also useful for the alleviation of one or more symptoms associated with such infections and cancer. |
FILED | Monday, December 30, 2013 |
APPL NO | 14/144304 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 38/1709 (20130101) A61K 39/39 (20130101) A61K 39/39558 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/74 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/5011 (20130101) G01N 33/57484 (20130101) G01N 2800/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457097 | Lencer et al. |
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FUNDED BY |
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APPLICANT(S) | Wayne I. Lencer (Jamaica Plain, Massachusetts); Daniel J F Chinnapen (Quincy, Massachusetts); Randy Mrsny (Bath, United Kingdom) |
ASSIGNEE(S) | Children's Medical Corporation (Boston, Massachusetts) |
INVENTOR(S) | Wayne I. Lencer (Jamaica Plain, Massachusetts); Daniel J F Chinnapen (Quincy, Massachusetts); Randy Mrsny (Bath, United Kingdom) |
ABSTRACT | Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER). |
FILED | Friday, September 04, 2009 |
APPL NO | 13/062638 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/4823 (20130101) A61K 47/48046 (20130101) Original (OR) Class A61K 47/48092 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457098 | DeSimone et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Mathew Finniss (Sussex, Canada); Mary Napier (Chapel Hill, North Carolina); Ashish Pandya (Morrisville, North Carolina); Matthew Parrott (Carrboro, North Carolina) |
ABSTRACT | Asymmetric bifunctional silyl (ABS) monomers comprising covalently linked pharmaceutical, chemical and biological agents are described. These agents can also be covalently bound via the silyl group to delivery vehicles for delivering the agents to desired targets or areas. Also described are delivery vehicles which contain ABS monomers comprising covalently linked agents and to vehicles that are covalently linked to the ABS monomers. The silyl modifications described herein can modify properties of the agents and vehicles, thereby providing desired solubility, stability, hydrophobicity and targeting. |
FILED | Wednesday, September 10, 2014 |
APPL NO | 14/482624 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/4823 (20130101) A61K 47/48023 (20130101) A61K 47/48176 (20130101) Original (OR) Class A61K 47/48215 (20130101) A61K 47/48238 (20130101) A61K 47/48823 (20130101) A61K 47/48869 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/083 (20130101) C07F 7/184 (20130101) C07F 7/1868 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 23/00 (20130101) Peptides C07K 19/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457099 | Sinko et al. |
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FUNDED BY |
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APPLICANT(S) | Patrick J. Sinko (Annandale, New Jersey); Jieming Gao (New Brunswick, New Jersey); Yashveer Singh (Highland Park, New Jersey); Xiaoping Zhang (Edison, New Jersey); Matthew S. Palombo (Marmora, New Jersey); Stanley Stein (East Brunswick, New Jersey) |
ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
INVENTOR(S) | Patrick J. Sinko (Annandale, New Jersey); Jieming Gao (New Brunswick, New Jersey); Yashveer Singh (Highland Park, New Jersey); Xiaoping Zhang (Edison, New Jersey); Matthew S. Palombo (Marmora, New Jersey); Stanley Stein (East Brunswick, New Jersey) |
ABSTRACT | The instant invention relates to polyethylene glycol-based dendrons, otherwise known as PEGtide dendrons, compositions thereof and methods of use. |
FILED | Monday, November 14, 2011 |
APPL NO | 13/296213 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/34 (20130101) A61K 47/48215 (20130101) Original (OR) Class A61K 2039/645 (20130101) A61K 2039/6093 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457101 | Gemeinhart et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Richard Gemeinhart (Chesterton, Indiana); Jason Buhrman (Glendale Heights, Illinois); Jamie Rayahin (Des Plaines, Illinois) |
ABSTRACT | Disclosed herein is a hydrogel composition comprising a polymer covalently linked to glutathione (GSH). Also disclosed herein is a method for providing localized delivery of one or more agents in a subject suffering from a disease. The method comprises administering to the subject a GST/GSH affinity hydrogel comprising a therapeutically effective amount of the one or more agents. |
FILED | Thursday, June 06, 2013 |
APPL NO | 14/405701 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 38/00 (20130101) A61K 47/32 (20130101) A61K 47/48215 (20130101) A61K 47/48784 (20130101) Original (OR) Class A61K 49/0047 (20130101) A61K 49/0091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457103 | Schaffer et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | David V. Schaffer (Danville, California); Ryan R. Klimczak (San Francisco, California); James T. Koerber (San Francisco, California); John G. Flannery (Berkeley, California) |
ABSTRACT | The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease. |
FILED | Wednesday, January 15, 2014 |
APPL NO | 14/156133 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/05 (20130101) A01K 2227/105 (20130101) A01K 2267/0356 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) A61K 38/00 (20130101) A61K 38/179 (20130101) A61K 38/185 (20130101) A61K 38/1808 (20130101) A61K 38/1825 (20130101) A61K 48/0008 (20130101) Original (OR) Class A61K 48/0075 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14145 (20130101) C12N 2810/855 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09457128 — Scaffolds comprising nanoelectronic components for cells, tissues, and other applications
US 09457128 | Lieber et al. |
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FUNDED BY |
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APPLICANT(S) | Charles M. Lieber (Lexington, Massachusetts); Jia Liu (Somerville, Massachusetts); Bozhi Tian (Chicago, Illinois); Tal Dvir (Rishon le Zion, Israel); Robert S. Langer (Newton, Massachusetts); Daniel S. Kohane (Newton, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Charles M. Lieber (Lexington, Massachusetts); Jia Liu (Somerville, Massachusetts); Bozhi Tian (Chicago, Illinois); Tal Dvir (Rishon le Zion, Israel); Robert S. Langer (Newton, Massachusetts); Daniel S. Kohane (Newton, Massachusetts) |
ABSTRACT | The present invention generally relates to nanoscale wires and tissue engineering. In various embodiments, cell scaffolds for growing cells or tissues can be formed that include nanoscale wires that can be connected to electronic circuits extending externally of the cell scaffold. The nanoscale wires may form an integral part of cells or tissues grown from the cell scaffold, and can even be determined or controlled, e.g., using various electronic circuits. This approach allows for the creation of fundamentally new types of functionalized cells and tissues, due to the high degree of electronic control offered by the nanoscale wires and electronic circuits. Accordingly, such cell scaffolds can be used to grow cells or tissues which can be determined and/or controlled at very high resolutions, due to the presence of the nanoscale wires, and such cell scaffolds will find use in a wide variety of novel applications, including applications in tissue engineering, prosthetics, pacemakers, implants, or the like. |
FILED | Wednesday, September 04, 2013 |
APPL NO | 14/018082 |
ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/04 (20130101) A61L 27/08 (20130101) A61L 27/025 (20130101) A61L 27/30 (20130101) Original (OR) Class A61L 27/38 (20130101) A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 27/507 (20130101) A61L 2400/12 (20130101) Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) C12M 35/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457132 | Donlan et al. |
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FUNDED BY |
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APPLICANT(S) | Rodney Martin Donlan (Atlanta, Georgia); Susan Marie Lehman (Atlanta, Georgia); Andres J. Garcia (Atlanta, Georgia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Rodney Martin Donlan (Atlanta, Georgia); Susan Marie Lehman (Atlanta, Georgia); Andres J. Garcia (Atlanta, Georgia) |
ABSTRACT | Medical devices that are resistant to biofilm development and methods of the manufacture of biofilm resistant medical devices are provided. One or more bacteriophages are tethered to the surface of a medical device or a hydrogei-type coating on the surface of the device by covalent bonding while maintaining bacteriophage infective or lytic activity. The presence of the bacteriophages on a medical device, such as an indwelling medical device, prevents biofilm formation or reduces existing biofilm formation on the surface of the device when in use. These devices address the long felt need for biofilm resistant devices that increase safety and reduce complications normally associated with prior indwelling or other medical devices. |
FILED | Thursday, June 28, 2012 |
APPL NO | 14/119716 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 25/34 (20130101) A01N 63/00 (20130101) A01N 63/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/36 (20130101) A61L 15/44 (20130101) A61L 15/60 (20130101) A61L 27/34 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/3637 (20130101) A61L 29/08 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 29/106 (20130101) Original (OR) Class A61L 29/145 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 31/145 (20130101) A61L 2300/102 (20130101) A61L 2300/104 (20130101) A61L 2300/404 (20130101) A61L 2300/406 (20130101) A61L 2300/606 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2025/0056 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2795/10132 (20130101) C12N 2795/10232 (20130101) C12N 2795/10332 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09457138 — Microfabricated artificial lung assist device, and methods of use and manufacture thereof
US 09457138 | Borenstein et al. |
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FUNDED BY |
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APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
INVENTOR(S) | Jeffrey T. Borenstein (Newton, Massachusetts); Joseph L. Charest (Cambridge, Massachusetts); James Ching-Ming Hsiao (Watertown, Massachusetts); Tatiana Kniazeva (Amherst, New Hampshire) |
ABSTRACT | The invention provides systems and methods for exchanging gas in an oxygenator device, and methods for preparing and using such oxygenator devices. The systems and methods can be used to transfer oxygen to blood to assist lung function in a patient. |
FILED | Tuesday, February 11, 2014 |
APPL NO | 14/177799 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1698 (20130101) Original (OR) Class A61M 1/3643 (20130101) Separation B01D 63/081 (20130101) B01D 63/082 (20130101) B01D 63/084 (20130101) B01D 63/088 (20130101) B01D 71/70 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457201 | Hoelscher et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Thilo Hoelscher (San Diego, California); Arne Voie (San Diego, California) |
ABSTRACT | Methods and apparatuses are provided for initiating stroke treatment “in the field” and/or during the transport of the patient to a care facility. The capability is provided to adjust automatically to the individual “therapeutic window” for each single patient, which is crucial because of the significant differences in skull morphology between humans of different age, gender and race. Further, the methods and apparatuses are based on the use of non-invasive application of ultrasound, as well as the non-invasive application of ultrasound in combination with an acoustically active agent, such as microbubbles, where stable cavitation of the microbubbles caused by the ultrasound may be relied upon as an underlying mechanism for both the therapeutic application as well as its control. |
FILED | Friday, May 10, 2013 |
APPL NO | 13/892187 |
ART UNIT | 3768 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) A61B 8/0808 (20130101) A61B 2017/22008 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/0245 (20130101) A61H 2201/018 (20130101) A61H 2201/105 (20130101) A61H 2201/0176 (20130101) A61H 2201/1604 (20130101) A61H 2201/5002 (20130101) A61H 2201/5005 (20130101) A61H 2201/5043 (20130101) A61H 2201/5058 (20130101) A61H 2201/5097 (20130101) A61H 2205/02 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101) A61N 2007/0052 (20130101) A61N 2007/0078 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458102 | Karpen et al. |
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FUNDED BY |
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APPLICANT(S) | OREGON HEALTH and SCEINCE UNIVERSITY (Portland, Oregon); WILLAMETTE UNIVERSITY (Salem, Oregon) |
ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
INVENTOR(S) | Jeffrey Karpen (Elk Grove, California); Sarah Kirk (Salem, Oregon); Adriana Andrade (Portland, Oregon); Michelle Schaffer (Frederick, Maryland); Kenneth Melich (Wilsonville, Oregon) |
ABSTRACT | Disclosed herein are derivatives of tetracaine that, among other things, block cyclic nucleotide gated (CNG) channels and are useful in the treatment of diseases characterized by overactive CNG channels such as retinal degeneration diseases. |
FILED | Friday, December 14, 2012 |
APPL NO | 13/715334 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/01 (20130101) A61K 31/13 (20130101) A61K 31/16 (20130101) A61K 31/21 (20130101) A61K 31/075 (20130101) A61K 31/095 (20130101) Acyclic or Carbocyclic Compounds C07C 229/60 (20130101) C07C 229/64 (20130101) C07C 237/34 (20130101) C07C 255/58 (20130101) C07C 327/48 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458124 | Dutta |
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FUNDED BY |
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APPLICANT(S) | Wayne State University (Detroit, Michigan) |
ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
INVENTOR(S) | Aloke K. Dutta (Troy, Michigan) |
ABSTRACT | Certain 3,6-disubstituted and 2,4,5-trisubstituted pyran derivatives that exhibit potent activity on monoamine transport systems are provided. The 3,6 and 2,4,5 pyrans are useful in probing the effects of their binding to monoamine transporter systems and the corresponding relationships to various afflictions affecting the CNS, or as a treatment for various CNS-related disorders in which the monoamine transport and related systems are implicated. |
FILED | Thursday, February 06, 2014 |
APPL NO | 14/173997 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 309/14 (20130101) Original (OR) Class C07D 405/12 (20130101) C07D 407/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458131 | Yoon et al. |
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FUNDED BY |
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APPLICANT(S) | Young-Sup Yoon (Atlanta, Georgia); Xiaodong Cheng (Decatur, Georgia); Ji Woong Han (Decatur, Georgia); Antonello Mai (Rome, Italy) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Young-Sup Yoon (Atlanta, Georgia); Xiaodong Cheng (Decatur, Georgia); Ji Woong Han (Decatur, Georgia); Antonello Mai (Rome, Italy) |
ABSTRACT | This disclosure relates to compounds, compositions and methods of epigenetically transforming cells. In certain embodiments, the disclosure relates to methods of generating epigenetically altered cells comprising mixing isolated cells with compositions disclosed herein under conditions such that epigenetically altered cells are formed. In certain embodiments, the disclosure contemplates inducing cells, such as adult somatic cells or cells that are not naturally pluripotent, into cells with chemically induce pluripotency. In certain embodiments, the disclosure contemplates certain compounds disclosed herein, compounds disclosed herein optionally substituted with one or more substituents, derivatives, or salts thereof, for these purposes. |
FILED | Thursday, November 08, 2012 |
APPL NO | 14/356024 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/541 (20130101) A61K 31/551 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 401/12 (20130101) Original (OR) Class C07D 401/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458141 | Gershengorn et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Forschungsverbund Berlin E.V. (Berlin-Adlershof, Germany) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Forschungsverbund Berlin, E.V. (Berlin-Adlershof, Germany) |
INVENTOR(S) | Marvin C. Gershengorn (Washington, District of Columbia); Susanne Neumann (Bethesda, Maryland); Bruce M. Raaka (Rockville, Maryland); Craig J. Thomas (Gaithersburg, Maryland); James Inglese (Bethesda, Maryland); Noel T. Southall (Chevy Chase, Maryland); Steven Titus (Elkridge, Maryland); Wei Zheng (Potomac, Maryland); Wenwei Huang (Rockville, Maryland); Gerd Krause (Berlin, Germany); Gunnar Kleinau (Berlin, Germany) |
ABSTRACT | Disclosed are oxo-hydroquinazolines that are useful as selective TSHR agonists. The compounds may be used for detecting or treating thyroid cancer, or treating a bone degenerative disorder. |
FILED | Tuesday, September 29, 2015 |
APPL NO | 14/869318 |
ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 49/0004 (20130101) A61K 51/00 (20130101) Heterocyclic Compounds C07D 239/91 (20130101) C07D 401/06 (20130101) C07D 405/06 (20130101) Original (OR) Class C07D 405/14 (20130101) C07D 487/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458147 | Pinkerton et al. |
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FUNDED BY |
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APPLICANT(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
ASSIGNEE(S) | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (La Jolla, California) |
INVENTOR(S) | Anthony B. Pinkerton (La Jolla, California); Russell Dahl (La Jolla, California); Nicholas D. P. Cosford (La Jolla, California); Jose Luis Millan (La Jolla, California) |
ABSTRACT | Described herein are compounds that modulate the activity of TNAP. In some embodiments, the compounds described herein inhibit TNAP. In certain embodiments, the compounds described herein are useful in the treatment of conditions associated with hyper-mineralization. |
FILED | Thursday, February 21, 2013 |
APPL NO | 14/379475 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/50 (20130101) Heterocyclic Compounds C07D 213/76 (20130101) C07D 213/80 (20130101) C07D 213/82 (20130101) C07D 215/38 (20130101) C07D 231/42 (20130101) C07D 237/20 (20130101) C07D 239/69 (20130101) C07D 241/22 (20130101) C07D 261/16 (20130101) C07D 263/50 (20130101) C07D 271/113 (20130101) C07D 277/52 (20130101) C07D 285/135 (20130101) C07D 333/36 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 405/04 (20130101) C07D 405/12 (20130101) C07D 409/04 (20130101) C07D 409/12 (20130101) C07D 417/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458160 | Maitra et al. |
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FUNDED BY |
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APPLICANT(S) | RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina) |
ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
INVENTOR(S) | Rangan Maitra (Cary, North Carolina); Alan Bradley Fulp (Willow Spring, North Carolina); Yanan Zhang (Apex, North Carolina); Herbert H. Seltzman (Raleigh, North Carolina) |
ABSTRACT | The invention provides compounds capable of acting as antagonists at cannabanoid receptors according to the following formula: Such compounds may be used to treat conditions for which the cannabinoid receptor system has been implicated, such as obesity, liver disease, diabetes, pain, and inflammation. |
FILED | Monday, October 26, 2015 |
APPL NO | 14/922583 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 473/34 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458213 | Rubin et al. |
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FUNDED BY |
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APPLICANT(S) | Mark A. Rubin (New York, New York); Dorothee Pflueger (Zurich, Switzerland); David S. Rickman (New York, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Mark A. Rubin (New York, New York); Dorothee Pflueger (Zurich, Switzerland); David S. Rickman (New York, New York) |
ABSTRACT | RNA transcripts representing a fusion of a human SLC45A3 nucleic acid and a human ELK4 nucleic acid that are associated with prostate cancer are described. Compositions and methods useful for detection of fusion transcripts of human SLC45A3 and ELK4 genetic sequences associated with cancer and useful for cancer therapy are provided. |
FILED | Friday, February 19, 2010 |
APPL NO | 13/202207 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/4748 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458215 | Lau et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); Loma Linda University (Loma Linda, California) |
ASSIGNEE(S) | Loma Linda University (Loma Linda, California); The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia) |
INVENTOR(S) | Kin-Hing William Lau (Redlands, California); Susan L. Hall (San Bernardino, California); Shin-Tai Chen (Colton, California); Subburaman Mohan (Redlands, California); David J. Baylink (Redlands, California) |
ABSTRACT | The present disclosure provides compositions and methods for increasing bone growth and/or enhancing wound healing, for example, fracture repair. The disclosure provides recombinant nucleic acids useful for promoting bone growth. For example, the disclosure provides recombinant nucleic acids that encode a fibroblast growth factor-2 (FGF-2) analog. The disclosure also provides vectors and cells incorporating these nucleic acids, as well as FGF-2 analogs encode by them. The disclosure also provides a mouse system of bone marrow transplantation and methods for producing as well as methods for using the system. Methods for inducing division and/or inducing differentiation of a hematopoietic stem cell are also provided, as are methods for enhancing bone growth and/or wound repair (for example, fracture repair). |
FILED | Tuesday, May 27, 2014 |
APPL NO | 14/287991 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2207/12 (20130101) A01K 2267/035 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1825 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2799/027 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458218 | Chilkoti |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina) |
ABSTRACT | The present invention provides therapeutic agents and compositions comprising elastic peptides and therapeutic proteins. Such peptides exhibit a flexible, extended conformation. In some embodiments, the therapeutic protein is a GLP-1 receptor agonist (e.g., GLP-1, exendin), insulin, or Factor VII/VIIa, including functional analogs. The present invention further provides encoding polynucleotides, as well as methods of making and using the therapeutic agents. The therapeutic agents have improvements in relation to their use as therapeutics, including, inter alia, one or more of half-life, clearance and/or persistance in the body, solubility, and bioavailability. |
FILED | Tuesday, March 04, 2014 |
APPL NO | 14/196943 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/28 (20130101) A61K 38/2278 (20130101) A61K 38/2278 (20130101) A61K 38/4846 (20130101) A61K 38/4846 (20130101) A61K 45/06 (20130101) A61K 47/48246 (20130101) A61K 47/48292 (20130101) A61K 47/48315 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/52 (20130101) C07K 14/61 (20130101) Original (OR) Class C07K 14/62 (20130101) C07K 14/71 (20130101) C07K 14/78 (20130101) C07K 14/605 (20130101) C07K 14/745 (20130101) C07K 2319/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458226 | Wrammert et al. |
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FUNDED BY |
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APPLICANT(S) | Jens Wrammert (Decatur, Georgia); Rafi Ahmed (Atlanta, Georgia); Patrick Wilson (Chicago, Illinois) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Jens Wrammert (Decatur, Georgia); Rafi Ahmed (Atlanta, Georgia); Patrick Wilson (Chicago, Illinois) |
ABSTRACT | Antibodies that bind with high affinity to swine H1N1 virus are described. In vivo experiments showed that one such antibody is able to fully protect mice challenged with a lethal dose of swine H1N1 virus. The antibody is also able to cure mice in a therapeutic setting when treated as late as up to 60 hours (2.5 days) after infection with swine H1N1 virus. Also described are recombinant forms of this antibody. |
FILED | Tuesday, October 12, 2010 |
APPL NO | 13/500879 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/76 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458227 | Pier et al. |
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FUNDED BY |
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APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Gerald B. Pier (Brookline, Massachusetts); Casie Anne Kelly-Quintos (Costa Mesa, California); Lisa Cavacini (Natick, Massachusetts); Marshall R. Posner (Mount Vernon, New York) |
ABSTRACT | The present invention relates to peptides, particularly human monoclonal antibodies, that bind specifically to poly-N-acetyl glucosamine (PNAG), such as Staphylococcal PNAG, in acetylated, partially acetylated and/or fully deacetylated form. The invention further provides methods for using these peptides in the diagnosis, prophylaxis and therapy of infections by bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Some antibodies of the invention enhance opsonophagocytic killing and in vivo protection against bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Compositions of these peptides, including pharmaceutical compositions, are also provided, as are functionally equivalent variants of such peptides. |
FILED | Wednesday, November 19, 2014 |
APPL NO | 14/548173 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/12 (20130101) Original (OR) Class C07K 16/1271 (20130101) C07K 2317/21 (20130101) C07K 2317/56 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458420 | Dondzillo et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
INVENTOR(S) | Anna Dondzillo (Denver, Colorado); Achim Klug (Denver, Colorado); Tim C. Lei (Thornton, Colorado) |
ABSTRACT | A system and methods by which in vitro experiments directed to a subject may be managed more efficiently including the more efficient use of a nutrient solution used in certain in vitro experimentation. Certain embodiments of the system and methods may include a retainer in which the subject of the experimentation and a nutrient solution is retainable and a recycling component that facilitates the restoration or reconditioning of the nutrient solution during the period of experimentation. |
FILED | Thursday, September 11, 2014 |
APPL NO | 14/483883 |
ART UNIT | 1799 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 23/04 (20130101) C12M 23/34 (20130101) C12M 27/20 (20130101) C12M 41/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458456 | Singh et al. |
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FUNDED BY |
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APPLICANT(S) | Ajay Pratap Singh (Mobile, Alabama); Sanjeev Srivastava (Mobile, Alabama); Seema Singh (Mobile, Alabama) |
ASSIGNEE(S) | UNIVERSITY OF SOUTH ALABAMA (Mobile, Alabama) |
INVENTOR(S) | Ajay Pratap Singh (Mobile, Alabama); Sanjeev Srivastava (Mobile, Alabama); Seema Singh (Mobile, Alabama) |
ABSTRACT | Some embodiments of the present technology relate to methods and compositions for the diagnosis and treatment of cancer. Some embodiments include methods and compositions for the diagnosis and treatment of castration-resistant prostate cancer. Some embodiments include methods and compositions for the diagnosis and treatment of pancreatic cancer. |
FILED | Friday, March 30, 2012 |
APPL NO | 14/007938 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1135 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/111 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57434 (20130101) G01N 33/57438 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458458 | Bassell et al. |
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FUNDED BY |
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APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Gary J. Bassell (Snellville, Georgia); Xiaodi Yao (Decatur, Georgia); Christina Gross (Decatur, Georgia) |
ABSTRACT | This disclosure relates to manipulating microRNA for the management of neurological disorders and compositions related thereto. In certain embodiments, the disclosure contemplates inhibition of miR324 or miR324-5p, e.g., the use of nucleobase polymers for antisense disruptions or RNA interference of miR-324 expression or for miR324-5p binding in order to increase Kv4.2 expression. In certain embodiments, the disclosure relates to methods of treating or preventing a neurological disease or condition comprising administering an effective amount of an inhibitor to a subject in need thereto. |
FILED | Tuesday, September 02, 2014 |
APPL NO | 14/474965 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/315 (20130101) C12N 2310/3231 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458464 | Tao |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Yuanxiang Tao (Boonton, New Jersey) |
ABSTRACT | The present invention relates to the field of neurology. More specifically, the present invention provides methods and composition useful for treating neuropathic pain. In a specific embodiment, the present invention provides a recombinant Kcna2 sense fragment. In another embodiment, the present invention provides a method of treating neuropathic pain comprising the step of administering a composition comprising a recombinant Kcna2 sense fragment. |
FILED | Monday, June 23, 2014 |
APPL NO | 14/312152 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/111 (20130101) C12N 2310/113 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458465 | Weisleder et al. |
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FUNDED BY |
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APPLICANT(S) | Noah Weisleder (Elizabeth, New Jersey); Chuanxi Cai (Highland Park, New Jersey); Jianjie Ma (Belle Mead, New Jersey) |
ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
INVENTOR(S) | Noah Weisleder (Elizabeth, New Jersey); Chuanxi Cai (Highland Park, New Jersey); Jianjie Ma (Belle Mead, New Jersey) |
ABSTRACT | Disclosed herein are compositions and methods for repairing cell membranes. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the repair of cell membranes. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with cell membrane damage. |
FILED | Thursday, December 04, 2008 |
APPL NO | 12/328646 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/53 (20130101) Peptides C07K 14/4716 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/62 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458473 | Lupold et al. |
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FUNDED BY |
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APPLICANT(S) | Shawn Edward Lupold (Ellicott City, Maryland); Ping Wu (Baltimore, Maryland); Ronald Rodriguez (Glenwood, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Shawn Edward Lupold (Ellicott City, Maryland); Ping Wu (Baltimore, Maryland); Ronald Rodriguez (Glenwood, Maryland) |
ABSTRACT | The present invention relates to the field of viral gene therapy. More specifically, the present invention provides compositions and methods for retargeting virus constructs. In one embodiment, the present invention provides an adenoviral construct comprising a nucleic acid encoding the peptide sequence MAE-X-PDP (SEQ ID NO:45), wherein X is an antigen targeting peptide. In a more specific embodiment, an adenoviral construct comprises a nucleic acid sequence encoding the peptide sequence MAEWQPDTAHHWALTLPDP (SEQ ID NO:10) inserted into the HI-loop of adenovirus fiber protein. In yet another embodiment, the present invention provides a method for optimizing adenoviral infection of target cells comprising the steps of (a) generating a peptide-display adenovirus library, wherein the displayed peptide is a peptide that specifically binds an antigen expressed on the surface of a target cell, and wherein the displayed peptide is flanked by random peptide sequences; and (b) screening the peptide-display adenovirus library against the target cells. |
FILED | Wednesday, June 29, 2011 |
APPL NO | 13/807359 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/1037 (20130101) C12N 2710/10322 (20130101) C12N 2710/10343 (20130101) C12N 2710/10345 (20130101) C12N 2810/40 (20130101) C12N 2820/007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458479 | Townsend et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Craig Arthur Townsend (Baltimore, Maryland); Micah Jeffrey Bodner (Dexter, Oregon); Ryan Martin Phelan (Emeryville, California); Michael Francis Freeman (Bonn, Germany) |
ABSTRACT | The presently disclosed subject matter demonstrates that ThnG and ThnQ enzymes encoded by the thienamycin gene cluster in Streptomyces cattleya oxidize the C-2 and C-6 moieties of carbapenems, respectively. ThnQ stereospecifically hydroxylates PS-5 giving N-acetyl thienamycin. ThnG catalyzes sequential desaturation and sulfoxidation of PS-5, giving PS-7 and its sulfoxide. The ThnG and ThnQ enzymes are relatively substrate selective, but give rise to the oxidative diversity of carbapenems produced by S. cattleya, and orthologues likely function similarly in allied streptomyces. |
FILED | Monday, September 21, 2015 |
APPL NO | 14/860103 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 477/20 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/10 (20130101) Original (OR) Class C12P 17/184 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458492 | Iadonato et al. |
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FUNDED BY |
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APPLICANT(S) | Shawn P Iadonato (Seattle, Washington); Kristin Bedard (Seattle, Washington) |
ASSIGNEE(S) | Kineta, Inc. (Seattle, Washington) |
INVENTOR(S) | Shawn P Iadonato (Seattle, Washington); Kristin Bedard (Seattle, Washington) |
ABSTRACT | Disclosed herein are methods for identifying compounds for the treatment of viral infection, including RNA viral infection and uses of the compounds as pharmaceutical compositions. The identified compounds modulate the RIG-I pathway in vertebrate cells. |
FILED | Thursday, February 23, 2012 |
APPL NO | 14/001472 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) A61K 31/5415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16111 (20130101) C12N 2770/24111 (20130101) C12N 2770/24211 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) C12Q 1/66 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458495 | Yao et al. |
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FUNDED BY |
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APPLICANT(S) | Mylene W. M. Yao (Stanford, California); Wing H. Wong (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Mylene W. M. Yao (Stanford, California); Wing H. Wong (Stanford, California) |
ABSTRACT | Methods and computer-based systems for facilitating assessment of clinical infertility are provided. The methods and systems can be implemented to, for example, facilitate assessment of a subject for an in vitro fertilization treatment cycle, including determining probability of a live birth event. The methods and systems can be implemented to, for example, facilitate a determination of success implantation of embryos, selection of an optimal number of embryos to transfer, and determination of success in subsequent in vitro fertilization treatment cycles following an unsuccessful treatment cycle. |
FILED | Wednesday, July 01, 2009 |
APPL NO | 12/496493 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/425 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/20 (20130101) G06F 19/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458505 | Eng |
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FUNDED BY |
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APPLICANT(S) | Charis Eng (Cleveland Heights, Ohio) |
ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
INVENTOR(S) | Charis Eng (Cleveland Heights, Ohio) |
ABSTRACT | A method of diagnosing Cowden syndrome (CS) and Cowden-like Syndrome (CLS) is described. The method includes diagnosing CS and CLS in a subject by identifying a decrease in expression of the KILLIN gene, or by identifying hypermethylation of the KILLIN promoter region. Kits for diagnosing CS and CLS by identifying subjects having KILLIN promoter region hypermethylation and primers specific for a methylated KILLIN promoter region are also described. |
FILED | Thursday, December 20, 2012 |
APPL NO | 13/721696 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458508 | Morris et al. |
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FUNDED BY |
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APPLICANT(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
INVENTOR(S) | Stephan W. Morris (Germantown, Tennessee); Qin Jiang (Memphis, Tennessee); Xiaoli Cui (Memphis, Tennessee); Liquan Xue (Cordova, Tennessee) |
ABSTRACT | Compositions and methods for the diagnosis and treatment of a cancer that is resistant to at least one anaplastic lymphoma kinase (ALK) kinase inhibitor are provided herein. The present invention is based on the discovery of mutations within ALK that confer resistance to at least one ALK kinase inhibitor. Polynucleotides and polypeptides having at least one ALK inhibitor resistance mutation are provided and find use in methods and compositions useful in the diagnosis, prognosis, and/or treatment of diseases associated with aberrant ALK activity, more particularly, those that are resistant to at least one ALK kinase inhibitors. Methods and compositions are also provided for the identification of agents that can inhibit the kinase activity and/or reduce the expression level of the ALK resistance mutants. |
FILED | Wednesday, February 20, 2013 |
APPL NO | 13/771948 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/71 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458509 | Benenson et al. |
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FUNDED BY |
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APPLICANT(S) | Yaakov Benenson (Basel, Switzerland); Ron Weiss (Newton, Massachusetts); Liliana Wroblewska (Arlington, Massachusetts); Zhen Xie (Malden, Massachusetts) |
ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Yaakov Benenson (Basel, Switzerland); Ron Weiss (Newton, Massachusetts); Liliana Wroblewska (Arlington, Massachusetts); Zhen Xie (Malden, Massachusetts) |
ABSTRACT | Provided herein are high-input detector modules and multi-input biological classifier circuits and systems that integrate sophisticated sensing, information processing, and actuation in living cells and permit new directions in basic biology, biotechnology and medicine. The multi-input biological classifier circuits described herein comprise synthetic, scaleable transcriptional/post-transcriptional regulatory circuits that are designed to interrogate the status of a cell by simultaneously sensing expression levels of multiple endogenous inputs, such as microRNAs. The classifier circuits then compute whether to trigger a desired output or response if the expression levels match a pre-determined profile of interest. |
FILED | Friday, July 22, 2011 |
APPL NO | 13/811126 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 1/6897 (20130101) C12Q 1/6897 (20130101) C12Q 2525/207 (20130101) Electric Digital Data Processing G06F 19/20 (20130101) G06F 19/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458510 | DePinho et al. |
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FUNDED BY |
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APPLICANT(S) | Ronald A. DePinho (Houston, Texas); Zhihu Ding (Brookline, Massachusetts); Chang-Jiun Wu (Houston, Texas); Lynda Chin (Houston, Texas) |
ASSIGNEE(S) | MIETAMARK GENETICS, INC. (Cambridge, Massachusetts) |
INVENTOR(S) | Ronald A. DePinho (Houston, Texas); Zhihu Ding (Brookline, Massachusetts); Chang-Jiun Wu (Houston, Texas); Lynda Chin (Houston, Texas) |
ABSTRACT | The present invention provides a set of DETERMINANTS (e.g., genes and gene products) that can accurately inform about the risk of cancer progression and recurrence, as well as methods of their use. |
FILED | Tuesday, June 26, 2012 |
APPL NO | 14/127413 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57434 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458517 | Schaffer et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | David V. Schaffer (Danville, California); Ryan R. Klimczak (San Francisco, California); James T. Koerber (San Francisco, California); John G. Flannery (Berkeley, California); Deniz Dalkara Mourot (Berkeley, California); Meike Visel (El Cerrito, California); Leah C. T. Byrne (Berkeley, California) |
ABSTRACT | The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via intravitreal injection, compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease. |
FILED | Thursday, April 30, 2015 |
APPL NO | 14/701063 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14145 (20130101) C12N 2750/14152 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class C12Q 2600/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459188 | Bruening et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
INVENTOR(S) | Merlin L. Bruening (East Lansing, Michigan); Gregory L. Baker (East Lansing, Michigan); Somnath Bhattacharjee (Durham, North Carolina); Yiding Ma (Ann Arbor, Michigan) |
ABSTRACT | The disclosure relates to a process and related article for functionalizing a porous membrane by contacting the membrane with a polyacid polymer at low pH to stably adsorb a polyacid layer on the membrane pore surface. The resulting functionalized membrane is characterized by a high density of free acid groups, resulting in a higher specific capacity for its intended application. The process allows functionalization of porous membranes in a very simple, one-step process. Such functional membranes may find multiple uses, including rapid, selective binding of proteins for their purification or immobilization. |
FILED | Wednesday, March 13, 2013 |
APPL NO | 13/799380 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Separation B01D 15/3828 (20130101) B01D 67/0088 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/327 (20130101) B01J 20/328 (20130101) B01J 20/3265 (20130101) B01J 20/28033 (20130101) B01J 47/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/249991 (20150401) Y10T 436/25375 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459194 | Benner et al. |
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FUNDED BY |
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APPLICANT(S) | CARDIO METRIX (Pleasanton, California) |
ASSIGNEE(S) | |
INVENTOR(S) | William Henry Benner (Danville, California); Donald John Holve (Berkeley, California) |
ABSTRACT | Apparatuses, methods, and systems are disclosed for analyzing particles from about 0.001 to about 1 μm in diameter by controlling a gaseous medium through which the particles travel so that properties of the particles, such as diameter, electrical mobility, and charge, are measured. One embodiment of the disclosed apparatuses includes a particle source generator, a nozzle, a chamber, an electronic gate, and a detector. Resolution of the measurements made by the disclosed apparatuses is improved by use of a mathematical deconvolution of a spread in arrival times generated by particles of different sizes and charge levels and non-ideal background flow velocity variations. |
FILED | Friday, January 03, 2014 |
APPL NO | 14/147482 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0266 (20130101) Original (OR) Class G01N 2001/2223 (20130101) G01N 2015/0046 (20130101) G01N 2015/0053 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459258 | Tang et al. |
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FUNDED BY |
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APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana); TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (Indianapolis, Indiana); TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
INVENTOR(S) | Haixu Tang (Bloomington, Indiana); Yehia S. Mechref (Lubbock, Texas) |
ABSTRACT | Illustrative embodiments of methods and apparatus for identifying one or more intact glycopeptides in a sample are disclosed. According to one illustrative embodiment, a method may comprise receiving data representing a plurality of mass spectra obtained from mass spectrometry of the sample, scoring data representing each of the plurality of mass spectra against data associated with target glycopeptides, and identifying one or more intact glycopeptides in the sample based at least in part on the scoring of the data representing each of the plurality of mass spectra. |
FILED | Tuesday, May 21, 2013 |
APPL NO | 14/402686 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2440/38 (20130101) Electric Digital Data Processing G06F 19/70 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459335 | Riederer et al. |
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FUNDED BY |
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APPLICANT(S) | Stephen J Riederer (Rochester, Minnesota); Paul T Weavers (Rochester, Minnesota) |
ASSIGNEE(S) | Mayo Foundation For Medical Education and Reseach (Rochester, Minnesota) |
INVENTOR(S) | Stephen J Riederer (Rochester, Minnesota); Paul T Weavers (Rochester, Minnesota) |
ABSTRACT | A method for three-dimensional parallel magnetic resonance imaging (MRI) using an MRI system is provided. The method includes determining in-plane acceleration factors that optimize a selected criterion, such as an image quality criterion defined by maximal noise amplification in a reconstructed image. The estimated in-plane acceleration factors are used to establish a k-space sampling pattern, which is used to acquire k-space data. An image is reconstructed from the acquired k-space data using a parallel image reconstruction technique. |
FILED | Friday, September 13, 2013 |
APPL NO | 14/025983 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/56 (20130101) Original (OR) Class G01R 33/4822 (20130101) G01R 33/5611 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 09456792 | Grant et al. |
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FUNDED BY |
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APPLICANT(S) | Gerald T. Grant (Kensington, Maryland); Shayne A. Kondor (Powder Springs, Georgia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Gerald T. Grant (Kensington, Maryland); Shayne A. Kondor (Powder Springs, Georgia) |
ABSTRACT | A heading positioning apparatus and the method of use for cone-beam computed tomography (CBCT), and single photon emission computed tomography (SPECT). |
FILED | Thursday, June 12, 2014 |
APPL NO | 14/303368 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/04 (20130101) Original (OR) Class A61B 6/14 (20130101) A61B 6/035 (20130101) A61B 6/0407 (20130101) A61B 6/4085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457052 | Davis et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas A. Davis (Oak Hill, Virginia); Khairul Anam (Gaithersburg, Maryland); Eric A. Elster (Kensington, Maryland); Douglas K. Tadaki (Frederick, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Thomas A. Davis (Oak Hill, Virginia); Khairul Anam (Gaithersburg, Maryland); Eric A. Elster (Kensington, Maryland); Douglas K. Tadaki (Frederick, Maryland) |
ABSTRACT | A method inducing chimerism and allograft tolerance by co-infusion of stem/progenitor-like cells and donor cells, wherein the donor cells can be bone marrow cells. The method also comprises the conditioning comprising depletion of CD4+ and CD8+ T-cells and administration of low doses of anti-neoplastic drugs. The inventive method comprises an aspect wherein allograft tolerance is induced without systemically suppressing the immune system. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/210701 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/255 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 39/001 (20130101) A61K 45/06 (20130101) A61K 2035/122 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0605 (20130101) C12N 5/0667 (20130101) C12N 5/0668 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457853 | Anderfaas et al. |
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FUNDED BY |
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APPLICANT(S) | MillenWorks (Tustin, California) |
ASSIGNEE(S) | MillenWorks (Tustin, California) |
INVENTOR(S) | Eric N. Anderfaas (Westminster, California); Matthew M. O'Brien (Hermosa Beach, California) |
ABSTRACT | The track tension of a tracked vehicle is actively controlled by a track tensioner system that is positioned behind or within an idler wheel of a tracked vehicle. The system employs no exposed hydraulic line and is operable to default to a passive tensioning mode in the event of a system failure. The hydraulic circuit of the track tensioner system is powered by the rotation of the idler wheel inside which the system resides. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/830638 |
ART UNIT | 3618 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Motor Vehicles; Trailers B62D 55/305 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457889 | Filter |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Evan J. Filter (Philadelphia, Pennsylvania) |
ABSTRACT | A rotorcraft rotor comprises a blade having a pitch axis, a primary pitch horn for the blade, and a secondary horn opposite the primary pitch horn with respect to the pitch axis. |
FILED | Tuesday, September 24, 2013 |
APPL NO | 14/035934 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Aeroplanes; Helicopters B64C 11/30 (20130101) Original (OR) Class B64C 27/32 (20130101) B64C 27/46 (20130101) B64C 27/605 (20130101) B64C 27/615 (20130101) B64C 2027/7205 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457900 | Jones et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Kevin D. Jones (Seaside, California); Vladmir N. Dobrokhodov (Seaside, California) |
ABSTRACT | A multirotor mobile buoy combining MR-VTOL capability with environmentally hardened electronics, exchangeable sensor suites, and a solar recharge system and providing sensing in aquatic environments. The multirotor mobile buoy provides for the detection, classification and location of underwater objects using self-contained electronics, and repositions with aerial means using a plurality of rotors. The multirotor mobile buoy additionally incorporates solar panels for recharging of on-board batteries enabling the flight and other functions, and comprises a buoyant assembly and extended tether in order to promote stability in dynamic, open ocean environments. The multirotor mobile buoy may be employed singly or as a swarm of underwater detection platforms, and may utilize its positioning ability to optimize the effectiveness of sonobuoy systems arrayed as a distributed sensor field. |
FILED | Friday, March 18, 2016 |
APPL NO | 15/073831 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/00 (20130101) Aeroplanes; Helicopters B64C 25/54 (20130101) B64C 27/08 (20130101) B64C 39/02 (20130101) Original (OR) Class B64C 39/022 (20130101) B64C 2201/12 (20130101) B64C 2201/024 (20130101) B64C 2201/108 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458215 | Lau et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); Loma Linda University (Loma Linda, California) |
ASSIGNEE(S) | Loma Linda University (Loma Linda, California); The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia) |
INVENTOR(S) | Kin-Hing William Lau (Redlands, California); Susan L. Hall (San Bernardino, California); Shin-Tai Chen (Colton, California); Subburaman Mohan (Redlands, California); David J. Baylink (Redlands, California) |
ABSTRACT | The present disclosure provides compositions and methods for increasing bone growth and/or enhancing wound healing, for example, fracture repair. The disclosure provides recombinant nucleic acids useful for promoting bone growth. For example, the disclosure provides recombinant nucleic acids that encode a fibroblast growth factor-2 (FGF-2) analog. The disclosure also provides vectors and cells incorporating these nucleic acids, as well as FGF-2 analogs encode by them. The disclosure also provides a mouse system of bone marrow transplantation and methods for producing as well as methods for using the system. Methods for inducing division and/or inducing differentiation of a hematopoietic stem cell are also provided, as are methods for enhancing bone growth and/or wound repair (for example, fracture repair). |
FILED | Tuesday, May 27, 2014 |
APPL NO | 14/287991 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2207/12 (20130101) A01K 2267/035 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1825 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2799/027 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458329 | Wright et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Michael E. Wright (Ridgecrest, California); Andrew P. Chafin (Ridgecrest, California); Joseph W. Tsang (Ridgecrest, California) |
ABSTRACT | A composition and method of preparing and adding unique organic additives to a metal-free coating system followed by application then provides long term corrosion protection to a reactive metal surface. |
FILED | Tuesday, February 04, 2014 |
APPL NO | 14/172737 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458357 | Bellan et al. |
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FUNDED BY |
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APPLICANT(S) | Leon M. Bellan (Somerville, Massachusetts); Robert S. Langer (Newton, Massachusetts); Donald M. Cropek (Champaign, Illinois) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Leon M. Bellan (Somerville, Massachusetts); Robert S. Langer (Newton, Massachusetts); Donald M. Cropek (Champaign, Illinois) |
ABSTRACT | Methods for microfabricating composite materials and composite materials prepared there from are described herein. The sacrificial material can be etched or patterned to create a two-dimensional and/or three-dimensional sacrificial material structure. The resulting sacrificial material structure can be embedded in one or more embedding materials. The sacrificial material(s) are materials whose solubility can be altered by application of a stimulus typically pH, and/or temperature, light, pH, pressure, presence of absence of ions, and combinations thereof. The embedding materials can contain one or more additives that modify one or more properties of the embedding materials, such as degradation properties, porosity, mechanical properties, viscosity, conductive properties, and combinations thereof. The composite materials can be used in tissue engineering, drug screening, toxin detection, drug delivery, filtrations, bioseparations, and as microfluidic devices for fluid mixing and structural repair. |
FILED | Friday, March 02, 2012 |
APPL NO | 13/410600 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/14 (20130101) A61L 27/56 (20130101) A61L 2400/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 189/06 (20130101) C09D 193/02 (20130101) Natural Resins; French Polish; Drying-oils; Driers; Turpentine C09F 1/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458428 | Clegg et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Dennis Clegg (Ventura, California); David Buchholz (New York, New York); Roxanne Croze (Santa Barbara, California); Britney Pennington (Santa Barbara, California); Peter Coffey (Bedfordshire, United Kingdom); Lyndsay Leach (Goleta, California) |
ABSTRACT | The invention relates to the field of cell culture, specifically, the derivation of retinal pigmented epithelial cells from pluripotent cells. The invention comprises the use of various cell culture medium supplements, medium formulations, and methods of using such medium supplements and formulations, in order to effect the rapid differentiation of pluripotent cells into retinal pigmented epithelial cells with very high yields. The invention further includes cell culture media formulations for the efficient maintenance, propagation, and maturation of cultured retinal pigmented epithelial cells. |
FILED | Wednesday, June 05, 2013 |
APPL NO | 14/405730 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) Original (OR) Class C12N 2500/05 (20130101) C12N 2500/30 (20130101) C12N 2500/36 (20130101) C12N 2500/38 (20130101) C12N 2501/16 (20130101) C12N 2501/33 (20130101) C12N 2501/35 (20130101) C12N 2501/40 (20130101) C12N 2501/105 (20130101) C12N 2501/113 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/392 (20130101) C12N 2501/395 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/998 (20130101) C12N 2506/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458456 | Singh et al. |
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FUNDED BY |
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APPLICANT(S) | Ajay Pratap Singh (Mobile, Alabama); Sanjeev Srivastava (Mobile, Alabama); Seema Singh (Mobile, Alabama) |
ASSIGNEE(S) | UNIVERSITY OF SOUTH ALABAMA (Mobile, Alabama) |
INVENTOR(S) | Ajay Pratap Singh (Mobile, Alabama); Sanjeev Srivastava (Mobile, Alabama); Seema Singh (Mobile, Alabama) |
ABSTRACT | Some embodiments of the present technology relate to methods and compositions for the diagnosis and treatment of cancer. Some embodiments include methods and compositions for the diagnosis and treatment of castration-resistant prostate cancer. Some embodiments include methods and compositions for the diagnosis and treatment of pancreatic cancer. |
FILED | Friday, March 30, 2012 |
APPL NO | 14/007938 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1135 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/111 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57434 (20130101) G01N 33/57438 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458472 | Weiss et al. |
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FUNDED BY |
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APPLICANT(S) | Ron Weiss (Newton, Massachusetts); Priscilla E. M. Purnick (West Windsor, New Jersey); Caroline DeHart (Fort Lauderdale, Florida); Jon Monk (New York, New York); Aparna Swaminathan (Orefield, Pennsylvania) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Ron Weiss (Newton, Massachusetts); Priscilla E. M. Purnick (West Windsor, New Jersey); Caroline DeHart (Fort Lauderdale, Florida); Jon Monk (New York, New York); Aparna Swaminathan (Orefield, Pennsylvania) |
ABSTRACT | In its various embodiments, the invention provides, first, a composition comprising a vector for transfecting a cell. The vector comprises a first nucleic acid encoding an antisense agent having thereon an RNA interference target for a transcript of a gene endogenous to the cell. The vector further comprises a second nucleic acid that encodes a cell-killing agent. The second nucleic acid further comprises a sequence of nucleotides transcribable into a non-coding region of a transcript of the second nucleic acid, such that the non-coding region becomes an RNA interference target for the antisense agent. In the transfected cell, the vector operates to interfere with the expression of the cell-killing agent unless and until the vector senses certain endogenous gene signals, whereupon it releases the cell-killing agent. Second, the invention provides a method of treating a disease in a patient by killing cells responsible for the disease, the method comprising administering the vector to the patient until the disease, or a symptom thereof, is ameliorated. |
FILED | Thursday, October 15, 2009 |
APPL NO | 12/587994 |
ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/13 (20130101) A61K 48/0058 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2740/15043 (20130101) C12N 2840/005 (20130101) C12N 2840/007 (20130101) C12N 2840/85 (20130101) C12N 2840/102 (20130101) C12N 2999/007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458509 | Benenson et al. |
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FUNDED BY |
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APPLICANT(S) | Yaakov Benenson (Basel, Switzerland); Ron Weiss (Newton, Massachusetts); Liliana Wroblewska (Arlington, Massachusetts); Zhen Xie (Malden, Massachusetts) |
ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Yaakov Benenson (Basel, Switzerland); Ron Weiss (Newton, Massachusetts); Liliana Wroblewska (Arlington, Massachusetts); Zhen Xie (Malden, Massachusetts) |
ABSTRACT | Provided herein are high-input detector modules and multi-input biological classifier circuits and systems that integrate sophisticated sensing, information processing, and actuation in living cells and permit new directions in basic biology, biotechnology and medicine. The multi-input biological classifier circuits described herein comprise synthetic, scaleable transcriptional/post-transcriptional regulatory circuits that are designed to interrogate the status of a cell by simultaneously sensing expression levels of multiple endogenous inputs, such as microRNAs. The classifier circuits then compute whether to trigger a desired output or response if the expression levels match a pre-determined profile of interest. |
FILED | Friday, July 22, 2011 |
APPL NO | 13/811126 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 1/6897 (20130101) C12Q 1/6897 (20130101) C12Q 2525/207 (20130101) Electric Digital Data Processing G06F 19/20 (20130101) G06F 19/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458510 | DePinho et al. |
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FUNDED BY |
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APPLICANT(S) | Ronald A. DePinho (Houston, Texas); Zhihu Ding (Brookline, Massachusetts); Chang-Jiun Wu (Houston, Texas); Lynda Chin (Houston, Texas) |
ASSIGNEE(S) | MIETAMARK GENETICS, INC. (Cambridge, Massachusetts) |
INVENTOR(S) | Ronald A. DePinho (Houston, Texas); Zhihu Ding (Brookline, Massachusetts); Chang-Jiun Wu (Houston, Texas); Lynda Chin (Houston, Texas) |
ABSTRACT | The present invention provides a set of DETERMINANTS (e.g., genes and gene products) that can accurately inform about the risk of cancer progression and recurrence, as well as methods of their use. |
FILED | Tuesday, June 26, 2012 |
APPL NO | 14/127413 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57434 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458534 | Shen |
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FUNDED BY |
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APPLICANT(S) | Mo-How Herman Shen (Dublin, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Mo-How Herman Shen (Dublin, Ohio) |
ABSTRACT | A method to increase the damping of a substrate using a face-centered cubic ferromagnetic damping coating having high damping loss attributes when a strain amplitude is 500-2000 micro-strain, and/or maximum damping loss attributes that occurs when the strain amplitude is greater than 250 micro-strain, and a turbine component having a face-centered cubic ferromagnetic damping coating. |
FILED | Tuesday, October 22, 2013 |
APPL NO | 14/059549 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/01 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/14 (20130101) C23C 14/16 (20130101) Original (OR) Class C23C 14/24 (20130101) C23C 14/30 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/507 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12576 (20150115) Y10T 428/12931 (20150115) Y10T 428/12986 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458727 | Shen |
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FUNDED BY |
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APPLICANT(S) | Mo-How Herman Shen (Dublin, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Mo-How Herman Shen (Dublin, Ohio) |
ABSTRACT | A turbine component having a low residual stress ferromagnetic damping coating. The ferromagnetic damping coating may include a ferromagnetic damping material applied in at least partially molten powder form, which may be directed at a surface of the substrate at an application velocity so that it causes partial plastic deformation of the surface while adhering to the surface of the substrate and solidifying in less than 3 seconds to create a ferromagnetic damping coating, resulting in a coated substrate. The ferromagnetic damping coating has a balanced coating residual stress, including a tensile quenching stress component and a compressive peening stress component. The balanced coating residual stress is within a range of ±50 MPa without having to subject the coated substrate to a high temperature annealing process. The resulting coated substrate exhibits a high damping capacity. |
FILED | Monday, March 10, 2014 |
APPL NO | 14/202314 |
ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/01 (20130101) Alloys C22C 19/07 (20130101) C22C 38/06 (20130101) C22C 38/18 (20130101) C22C 38/22 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/08 (20130101) C23C 4/129 (20160101) C23C 24/04 (20130101) C23C 30/00 (20130101) C23C 30/005 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/1275 (20150115) Y10T 428/2495 (20150115) Y10T 428/12757 (20150115) Y10T 428/12778 (20150115) Y10T 428/12806 (20150115) Y10T 428/12931 (20150115) Y10T 428/12937 (20150115) Y10T 428/12951 (20150115) Y10T 428/12958 (20150115) Y10T 428/12972 (20150115) Y10T 428/12979 (20150115) Y10T 428/24942 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458889 | Thomas |
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FUNDED BY |
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APPLICANT(S) | Randall R. Thomas (Fort Worth, Texas) |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Randall R. Thomas (Fort Worth, Texas) |
ABSTRACT | A bearing system includes a bearing comprising a first end and a second end opposite to the first end. The bearing further comprises a plurality of threads adjacent to the second end. The plurality of threads comprise a first slot perpendicular to the plurality of threads. The bearing system also includes a washer comprising a first surface adjacent to the second end of the bearing and a plane parallel to the first surface. The washer further comprises a plurality of side tabs extending from a second surface in a direction parallel to the plane and a first tab extending from the first surface in a direction perpendicular to the plane. The first tab mates with the first slot of the bearing. The bearing system further comprises a nut positioned between the first end of the bearing and the first surface of the washer. |
FILED | Friday, February 20, 2015 |
APPL NO | 14/627829 |
ART UNIT | 3656 — Material and Article Handling |
CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 43/003 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 17/02 (20130101) F16C 35/02 (20130101) Original (OR) Class F16C 43/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458989 | Hsu et al. |
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FUNDED BY |
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APPLICANT(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Cambridge, Massachusetts); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Cambridge, Massachusetts); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | Disclosed herein are transparent color displays with nanoparticles made with nonlinear materials and/or designed to exhibit optical resonances. These nanoparticles are embedded in or hosted on a transparent substrate, such as a flexible piece of clear plastic or acrylic. Illuminating the nanoparticles with invisible light (e.g., infrared or ultraviolet light) causes them to emit visible light. For example, a rare-earth doped nanoparticle may emit visible light when illuminated simultaneoulsy with a first infrared beam at a first wavelength λ1 and a second infrared beam at a second wavelength λ2. And a frequency-doubling nanoparticle may emit visible light when illuminated with a single infrared beam at the nanoparticle's resonant frequency. Selectively addressing these nanoparticles with appropiately selected pump beams yields visible light emitted from the nanoparticles hosted by the transparent substrate in a desired pattern. |
FILED | Monday, December 30, 2013 |
APPL NO | 14/143558 |
ART UNIT | 2875 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 9/08 (20130101) F21V 9/12 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/19 (20130101) G02F 1/0126 (20130101) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 13/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459009 | Gupta |
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FUNDED BY |
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APPLICANT(S) | University of Maryland (College Park, Maryland) |
ASSIGNEE(S) | UNIVERSITY OF MARYLAND (College Park, Maryland) |
INVENTOR(S) | Ashwani K Gupta (College Park, Maryland) |
ABSTRACT | Colorless distributed combustion (CDC) reactors or green combustion gas turbine combustors having a combustion chamber are presented for improved performance of gas turbine combustion engines. The combustors are configured and designed for providing a superior pattern factor (uniform thermal field in the combustion zone) and a reduction or complete elimination of pollutants emission from the combustor (i.e., zero emission gas turbine combustor) and uniform thermal field in the entire combustion zone to provide significantly improved pattern factor. Colorless distributed combustion is achieved with fuel and air entering the combustion chamber via one or more injection ports as non-premixed, or premixed. Rectangular, cylindrical, stadium and elliptical shaped combustors are presented with injection ports and exit ports located in various locations of the combustors. The mixture preparation between fuel and air with the hot combustion products is carried out either with the gases present in the combustion chamber or via a communication link between the exit gases from the combustor back to the combustion chamber. |
FILED | Monday, March 24, 2014 |
APPL NO | 14/223378 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/22 (20130101) Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 9/006 (20130101) F23C 2900/99001 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/20 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/342 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/671 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459024 | Ghasemi et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Hadi Ghasemi (Houston, Texas); Amy Marie Marconnet (West Lafayette, Indiana); Gang Chen (Carlisle, Massachusetts); George Wei Ni (Ann Arbor, Michigan) |
ABSTRACT | A localized heating structure, and method of forming same, for use in solar systems includes a thermally insulating layer having interconnected pores, a density of less than about 3000 kg/m3, and a hydrophilic surface, and an expanded carbon structure adjacent to the thermally insulating layer. The expanded carbon structure has a porosity of greater than about 80% and a hydrophilic surface. |
FILED | Saturday, September 06, 2014 |
APPL NO | 14/479307 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 5/32 (20130101) B32B 2266/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2205/026 (20130101) C08J 2383/02 (20130101) Compositions of Macromolecular Compounds C08L 83/02 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/28 (20130101) F24J 2/42 (20130101) F24J 2/48 (20130101) F24J 2/515 (20130101) Original (OR) Class F24J 2002/469 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/44 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) Y10T 428/249967 (20150401) Y10T 428/249969 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459079 | Dudt et al. |
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FUNDED BY |
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APPLICANT(S) | Philip Dudt (North Bethesda, Maryland); Alyssa Littlestone (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Philip Dudt (North Bethesda, Maryland); Alyssa Littlestone (Washington, District of Columbia) |
ABSTRACT | A lightweight armor for resisting penetration by both fragments and high velocity sharply pointed projectiles. The lightweight armor includes a slide region and a receiving region, with the slide region having a backing material coated with polyurea to slidably redirect projectiles towards the receiving region, which may include high strength thickened projectile stopping materials. |
FILED | Wednesday, September 30, 2015 |
APPL NO | 14/871495 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/023 (20130101) Original (OR) Class F41H 5/0457 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459189 | Beebe et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Scott M. Berry (Madison, Wisconsin); David J. Guckenberger (Oconomowoc, Wisconsin); Ben P. Casavant (Madison, Wisconsin) |
ABSTRACT | A device and a method are provided for isolating a fraction in a biological sample. The fraction is bound to solid phase substrate to define a fraction-bound solid phase substrate. The device includes an input zone for receiving the biological sample therein and a second zone for receiving an isolation fluid therein. A force is provided that is generally perpendicular to gravity. The force is movable between a first position adjacent the input zone and a second position adjacent the isolation zone. The force captures the fraction-bound solid phase substrate and the fraction-bound solid phase substrate moves from the input zone to the isolation zone in response to the force moving from the first position to the second position. |
FILED | Wednesday, April 02, 2014 |
APPL NO | 14/243086 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502792 (20130101) B01L 2200/0668 (20130101) B01L 2200/0673 (20130101) B01L 2300/087 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class G01N 1/4077 (20130101) G01N 35/0098 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459222 | Swager et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Katherine A. Mirica (Waltham, Massachusetts); Joseph M. Azzarelli (Cambridge, Massachusetts); Jonathan G. Weis (Somerville, Massachusetts); Jan Schnorr (Cambridge, Massachusetts); Birgit Esser (Bonn, Germany) |
ABSTRACT | Methods described herein may be useful in the fabrication and/or screening of devices (e.g., sensors, circuits, etc.) including conductive materials. In some embodiments, a conductive material is formed on a substrate using mechanical abrasion. The methods described herein may be useful in fabricating sensors, circuits, tags for remotely-monitored sensors or human/object labeling and tracking, among other devices. In some cases, devices for determining analytes are also provided. |
FILED | Wednesday, March 13, 2013 |
APPL NO | 13/800169 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/12 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459369 | Roach et al. |
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FUNDED BY |
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APPLICANT(S) | Blue Line Engineering Co. (Colorado Springs, Colorado) |
ASSIGNEE(S) | Blue Line Engineering Company (Colorado Springs, Colorado) |
INVENTOR(S) | Steven D. Roach (Colorado Springs, Colorado); Gregory H. Ames (Colorado Springs, Colorado); Philip N. Zercher (Colorado Springs, Colorado) |
ABSTRACT | A transconductor converts voltage on an inductive sensor to a proportional current using two “coupling” capacitors. Responsive to movement of an electrically conductive target from the null position a resonant current is formed between the two sensor coils. A single differential transistor pair switched by periodic drive signals commutes the net alternating current at the single input to direct current. |
FILED | Friday, October 04, 2013 |
APPL NO | 14/046083 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/2275 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/49 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459776 | Miller |
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APPLICANT(S) | U.S. Army Research Development and Engineering Command (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Dennis B. Miller (Rising Sun, Maryland) |
ABSTRACT | A device for use in studies involving multiple subjects to record observation data in an output file is provided. The invention may be embodied in a tablet type computer having a touchscreen or another form of electronic device having user input capability. The device displays a set of subject buttons for selecting a subject for which observation data will be recorded, a corresponding set of start time buttons to track and display the elapsed time for the corresponding subject, and a set of observation buttons corresponding to pre-defined observation data established by the user. Additional features may include, among other features, a reminder function for setting user-defined alarms, a time-stamped note function, and an initiation function for items such as time synchronization, describing subjects, and describing environmental or exposure details for the study to be performed. |
FILED | Wednesday, March 13, 2013 |
APPL NO | 13/799782 |
ART UNIT | 2172 — Selective Visual Display Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/12 (20130101) G06F 3/04842 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459891 | Paxton et al. |
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FUNDED BY |
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APPLICANT(S) | Nicholas A. Paxton (Cedar Rapids, Iowa); Ramy W. Henin (Marion, Iowa); Paul C. Rodriguez, Jr. (Marion, Iowa) |
ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
INVENTOR(S) | Nicholas A. Paxton (Cedar Rapids, Iowa); Ramy W. Henin (Marion, Iowa); Paul C. Rodriguez, Jr. (Marion, Iowa) |
ABSTRACT | A system for reading and writing data to virtual machines in a machine operating according to the ARINC 653 standard includes a plurality of virtual machines that intercommunicate and communicate over a bus. A data interceptor is connected to the bus for communication with each virtual machine by reading and writing data to each virtual machine. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/839183 |
ART UNIT | 2441 — Computer Networks |
CURRENT CPC | Electric Digital Data Processing G06F 9/455 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459949 | Fryman et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Joshua Bruce Fryman (Corvallis, Oregon); Allan Knies (Burlingame, California) |
ABSTRACT | Methods and apparatus to provide failure detection are disclosed herein. An example method to synchronize data operations between multiple workload units in a computing device to facilitate failure detection includes identifying a number of first data operations to write data from a computing node in a first workload unit to locations that are not in a local cache of the computing node and are not in a memory of the first workload unit, the first data operations corresponding to a set of computing instructions that are assigned to the first workload unit and, when a flag in the first workload unit has been set to a first value, synchronizing the first data operations with second data operations by a second workload unit. |
FILED | Thursday, September 04, 2014 |
APPL NO | 14/477438 |
ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 11/076 (20130101) G06F 11/079 (20130101) Original (OR) Class G06F 11/0709 (20130101) G06F 11/0757 (20130101) G06F 11/3476 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460241 | Gallacher et al. |
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FUNDED BY |
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APPLICANT(S) | Patrick C. Gallacher (Pearl River, Louisiana); Michael R. Schaferkotter (Gretna, Louisiana); David A. Hebert (Diamondhead, Mississippi) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Patrick C. Gallacher (Pearl River, Louisiana); Michael R. Schaferkotter (Gretna, Louisiana); David A. Hebert (Diamondhead, Mississippi) |
ABSTRACT | System and method for adjusting the values of the prognostic variables near the interface between a nonhydrostatic, high resolution model embedded in a hydrostatic, coarser resolution model. The system and method condition the outer domain lateral boundary values to enforce conservation of volume when the variables are interpolated onto the inner domain grid. The conditioning adjusts the baroclinic normal velocities at the open boundaries before interpolation. The system and method also include a relaxation scheme which matches the values of the prognostic variables across a zone near the open boundaries of the submesoscale inner domain to prevent the development of discontinuities, reflections and perimeter currents at the periphery of the inner domain. |
FILED | Wednesday, January 30, 2013 |
APPL NO | 13/753750 |
ART UNIT | 2123 — AI & Simulation/Modeling |
CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 2217/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460383 | Brezzo et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Bernard V. Brezzo (Somers, New York); Leland Chang (New York, New York); Steven K. Esser (San Jose, California); Daniel J. Friedman (Sleepy Hollow, New York); Yong Liu (Rye, New York); Dharmendra S. Modha (San Jose, California); Robert K. Montoye (Rochester, Minnesota); Bipin Rajendran (White Plains, New York); Jae-sun Seo (White Plains, New York); Jose A. Tierno (Stamford, Connecticut) |
ABSTRACT | A reconfigurable neural network circuit is provided. The reconfigurable neural network circuit comprises an electronic synapse array including multiple synapses interconnecting a plurality of digital electronic neurons. Each neuron comprises an integrator that integrates input spikes and generates a signal when the integrated inputs exceed a threshold. The circuit further comprises a control module for reconfiguring the synapse array. The control module comprises a global final state machine that controls timing for operation of the circuit, and a priority encoder that allows spiking neurons to sequentially access the synapse array. |
FILED | Tuesday, September 02, 2014 |
APPL NO | 14/475409 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460478 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Junshan Zhang (Chandler, Arizona); Miao He (Tempe, Arizona); Lei Yang (Tempe, Arizona); Vijay Vittal (Scottsdale, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Junshan Zhang (Chandler, Arizona); Miao He (Tempe, Arizona); Lei Yang (Tempe, Arizona); Vijay Vittal (Scottsdale, Arizona) |
ABSTRACT | Systems and methods for managing electricity of an electrical supply grid electrically connected to a wind farm are disclosed. Some systems and methods may include identifying relationships among a plurality of turbines in the wind farm with a minimum spanning tree, calculating a power output relationship among the plurality of turbines with the minimum spanning tree, creating a finite state space Markov chain forecast model for the plurality of turbines in the wind farm, predicting a power output of the wind farm with the finite state space Markov chain forecast model, and modifying at least one of a generation of electricity and a distribution of electricity based on the predicted power output of the wind farm. Also disclosed are systems and methods for predicting the power output of a wind farm. |
FILED | Tuesday, December 17, 2013 |
APPL NO | 14/109586 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 50/06 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/386 (20130101) H02J 2003/007 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/763 (20130101) Y02E 60/76 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Y04S 40/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460721 | Ouakil et al. |
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FUNDED BY |
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APPLICANT(S) | Lisa Ouakil (Oviedo, Florida); Abdelhamid Ouakil (Orlando, Florida); Ouns Mouri (San Diego, California); Peter Smith (Orlando, Florida) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Lisa Ouakil (Oviedo, Florida); Abdelhamid Ouakil (Orlando, Florida); Ouns Mouri (San Diego, California); Peter Smith (Orlando, Florida) |
ABSTRACT | The invention is system and method to recognize speech vocalizations using context-specific grammars and vocabularies. The system and method allow increased accuracy of recognized utterances by eliminating all language encodings irrelevant to the current context and allowing identification of appropriate context transitions. The system and method creates a context dependent speech recognition system with multiple supported contexts, each with specific grammar and vocabulary, and each identifying the potential context transition allowed. The system and method also include programmatic integration between the context dependent speech recognition system and other systems to make use of the recognized speech. |
FILED | Friday, January 16, 2015 |
APPL NO | 14/598958 |
ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
CURRENT CPC | Electric Digital Data Processing G06F 17/274 (20130101) G06F 17/2765 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/28 (20130101) Original (OR) Class G10L 15/065 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460863 | Li |
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FUNDED BY |
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APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | Xiaodong Li (Irmo, South Carolina) |
ABSTRACT | An asymmetric supercapacitor is described. The supercapacitor includes a first electrode, a second electrode, a thin film separator, and an electrolyte. The first electrode comprises functionalized cellulose fiber and the second electrode comprises functionalized cellulose fiber and metal oxide. |
FILED | Friday, April 19, 2013 |
APPL NO | 13/866103 |
ART UNIT | 2848 — Electrical Circuits and Systems |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/04 (20130101) H01G 11/30 (20130101) Original (OR) Class H01G 11/40 (20130101) H01G 11/46 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/43 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461112 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | Seung-Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Seung-Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
ABSTRACT | A method of epitaxially growing nitrogen-based compound semiconductor thin films on a semiconductor substrate, which is periodically patterned with grooves. The method can provide an epitaxial growth of a first crystalline phase epitaxial film on the substrate, and block the growth of an initial crystalline phase with barrier materials prepared at the sides of the grooves. Semiconductor devices employing the epitaxial films are also disclosed. |
FILED | Friday, August 14, 2015 |
APPL NO | 14/826925 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/16 (20130101) H01L 29/045 (20130101) H01L 29/0657 (20130101) Original (OR) Class H01L 29/2003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461193 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | Stephen R. Forrest (Ann Arbor, Michigan); Noel C. Giebink (State College, Pennsylvania) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Noel C. Giebink (State College, Pennsylvania) |
ABSTRACT | The present disclosure relates to focusing luminescent concentrators wherein directional emission, obtained by placing an absorber/emitter within a microcavity or photonic crystal, may be oriented by a macroscopic concentrator and focused to a point or line for 3D or 2D concentration, respectively. The focusing luminescent concentrators disclosed herein may provide high concentration ratios without the need for tracking, and may reduce re-absorption losses associated with conventional concentrators. The present disclosure further relates to photovoltaic cells and/or optical detector devices comprising a focusing luminescent concentrator. The devices and methods presently disclosed are also useful, for example, in solar, thermal and thermophotovolatic applications. |
FILED | Monday, May 14, 2012 |
APPL NO | 13/470938 |
ART UNIT | 1756 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/0422 (20130101) G01J 1/429 (20130101) G01J 1/0448 (20130101) G01J 1/0488 (20130101) G01J 1/4204 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/055 (20130101) Original (OR) Class H01L 31/0543 (20141201) H01L 31/0549 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461323 | Thampan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Tony M. Thampan (Bear, Delaware); Jonathan Novoa (North East, Maryland); Terrill B. Atwater (Bel Air, Maryland) |
ABSTRACT | A method of fabricating a hydrogen fuel cell cartridge is provided. Furthermore, a hydrogen fuel cell cartridge is provided. In addition, a hydrogen fuel cell system is provided, which includes a plurality of cartridge segments in a spiral configuration and a control unit. |
FILED | Tuesday, August 05, 2014 |
APPL NO | 14/452029 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/00 (20130101) B01J 7/02 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/001 (20130101) C01B 3/04 (20130101) C01B 3/065 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/065 (20130101) H01M 8/0606 (20130101) Original (OR) Class H01M 8/0656 (20130101) H01M 8/04201 (20130101) H01M 8/04208 (20130101) H01M 8/04216 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461731 | Cohen |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
INVENTOR(S) | Aaron E. Cohen (Alexandria, Virginia) |
ABSTRACT | A bent-pipe relay communication system and method of using same. The bent-pipe relay communication system includes a plurality of bent-pipe relay channels, each channel having automatic gain control. Each channel of the plurality of bent-pipe relay channels includes a radio -frequency-to-intermediate-frequency demodulator, at least one programmable variable gain amplifier, and an intermediate-frequency-to-radio-frequency modulator. The communication system further includes at least one radio frequency power detector operably connected to the intermediate-frequency-to-radio-frequency modulator for each channel. The system also includes at least one controller communicating with the at least one radio frequency power detector and the at least one variable gain amplifier for the each channel to provide the automatic gain control. |
FILED | Wednesday, December 09, 2015 |
APPL NO | 14/963354 |
ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Transmission H04B 1/40 (20130101) H04B 7/185 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461755 | Brewer et al. |
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FUNDED BY |
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APPLICANT(S) | ViaSat, Inc. (Carlsbad, California) |
ASSIGNEE(S) | ViaSat, Inc. (Carlsbad, California) |
INVENTOR(S) | Kenneth P. Brewer (Gilbert, Arizona); Salah M. Osman (Gilbert, Arizona) |
ABSTRACT | Enhanced RF system measurement including measurement of reflected power of a transmission system using two directional couplers configured to couple reflected power (e.g., isolate forward power). The directional couplers may be placed at a distance of ¼ wave separation and measurements from the two directional couplers may be averaged to obtain a reflected power for the transmission path. The enhanced measurement of reflected power may be used to obtain a more accurate VSWR or return loss measurement. An indication of the reflected power (e.g., VSWR, return loss, etc.) may be fed back to a source, which may adjust transmit power based on the measured VSWR to achieve a certain amount of power conveyed to the load (e.g., target radiated power from an antenna, etc.). Error conditions may be detected and the source may terminate transmission to prevent potential adverse operating conditions. |
FILED | Friday, January 16, 2015 |
APPL NO | 14/599338 |
ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 27/06 (20130101) G01R 29/10 (20130101) Transmission H04B 1/04 (20130101) H04B 17/103 (20150115) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461974 | Rohloff |
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FUNDED BY |
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APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
ASSIGNEE(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
INVENTOR(S) | Kurt Ryan Rohloff (South Hadley, Massachusetts) |
ABSTRACT | In a computer implemented method for data privacy in a distributed communication system, the method includes: storing a plurality of secret keys, each secret key for a respective one of a plurality of client terminals; identifying a mixer key; generating a plurality of key switch hints for the client terminals, each of the key switch hints generated for a respective client terminal of the client terminals, using the mixer key and a respective secret key for each respective client terminal; sending the key switch hints to a mixer; switching a first encrypted data stream received from a first client terminal of the client terminals to an encrypted output data stream using the key switch hints; and sending the encrypted output data stream to a receiving client terminal of the client terminals to be decrypted by the receiving client terminal. |
FILED | Friday, February 28, 2014 |
APPL NO | 14/194597 |
ART UNIT | 2437 — Cryptography and Security |
CURRENT CPC | Secret Communication; Jamming of Communication H04K 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) H04L 9/3093 (20130101) H04L 63/0471 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09462264 | Mateti et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Kiron Mateti (Bloomington, Indiana); Craig Armes (Washington, Indiana); Aaron Cole (Bloomington, Indiana); Josh Borneman (Bloomington, Indiana); Amanda Lin (Bloomington, Indiana) |
ABSTRACT | Systems and related methods are provided to perform optical characterization of system under tests (SUT), including one or more optical elements (OE), for various purposes including evaluation of optical resolution needed to distinguish image elements, blur, line of sight jitter, and/or pointing stability. Various testing systems and methods are provided including an embodiment having a vibration loading system (VLS), a first acceleration sensor coupled with the VLS, and a mounting structure adapted to receive the SUT. An illumination target system (ITS) emits light that passes through the SUT OE's lens and is captured by the SUT's imaging system. A light control system controls the ITS based on a plurality of activation commands and a Test Control System (TCS). The TCS receives ITS input through the SUT that is synchronized with acceleration sensor data (e.g. phase of VLS position) and analyzed via real-time or post-processing including image distortion analysis. |
FILED | Friday, August 07, 2015 |
APPL NO | 14/820799 |
ART UNIT | 2422 — Cable and Television |
CURRENT CPC | Image Data Processing or Generation, in General G06T 5/006 (20130101) G06T 7/2033 (20130101) G06T 2207/10004 (20130101) G06T 2207/20201 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) H04N 17/002 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 09457297 | Brown et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Erik P. Brown (Tracy, California); Jeffery L. Haslam (Livermore, California); Mark A. Mitchell (Dublin, California) |
ABSTRACT | A filter securing system including a filter unit body housing; at least one tubular filter element positioned in the filter unit body housing, the tubular filter element having a closed top and an open bottom; a dimple in either the filter unit body housing or the top of the tubular filter element; and a socket in either the filter unit body housing or the top of the tubular filter element that receives the dimple in either the filter unit body housing or the top of the tubular filter element to secure the tubular filter element to the filter unit body housing. |
FILED | Tuesday, December 04, 2012 |
APPL NO | 13/693984 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 29/52 (20130101) Original (OR) Class B01D 35/306 (20130101) B01D 46/2407 (20130101) B01D 46/2414 (20130101) B01D 2201/0453 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457429 | Borgeson et al. |
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FUNDED BY |
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APPLICANT(S) | Frank A. Borgeson (Scottsdale, Arizona); Joseph J. Hanak (Ames, Iowa); Ricky S. Harju (Luckey, Ohio); Karen M. Harju (Luckey, Ohio); Norman L. Helman (Scottsdale, Arizona); Kenneth R. Hecht (Gilbert, Arizona) |
ASSIGNEE(S) | First Solar, Inc. (Perrysburg, Ohio) |
INVENTOR(S) | Frank A. Borgeson (Scottsdale, Arizona); Joseph J. Hanak (Ames, Iowa); Ricky S. Harju (Luckey, Ohio); Norman L. Helman (Scottsdale, Arizona); Kenneth R. Hecht (Gilbert, Arizona) |
ABSTRACT | A method and apparatus for laser scribing coatings on glass sheet substrates. |
FILED | Wednesday, August 11, 2004 |
APPL NO | 10/915736 |
ART UNIT | 3744 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/40 (20130101) B23K 26/082 (20151001) B23K 26/364 (20151001) B23K 26/365 (20130101) B23K 26/0622 (20151001) B23K 26/0838 (20130101) Original (OR) Class B23K 26/4065 (20130101) B23K 26/4075 (20130101) B23K 2203/172 (20151001) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/001 (20130101) C03C 23/0025 (20130101) C03C 2218/328 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/0463 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457639 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Mingyu Wang (Amherst, New York); Prasad S. Kadle (Williamsville, New York); Debashis Ghosh (Williamsville, New York); Mark J. Zima (Clarence Center, New York); Edward Wolfe, IV (E Amherst, New York); Timothy D Craig (Williamsville, New York) |
ASSIGNEE(S) | MAHLE International GmbH (Stuttgart, Germany) |
INVENTOR(S) | Mingyu Wang (Amherst, New York); Prasad S. Kadle (Williamsville, New York); Debashis Ghosh (Williamsville, New York); Mark J. Zima (Clarence Center, New York); Edward Wolfe, IV (E Amherst, New York); Timothy D Craig (Williamsville, New York) |
ABSTRACT | A heating, ventilation, and air conditioning (HVAC) system and a method of controlling a HVAC system that is configured to provide a perceived comfortable ambient environment to an occupant seated in a vehicle cabin. The system includes a nozzle configured to direct an air stream from the HVAC system to the location of a thermally sensitive portion of the body of the occupant. The system also includes a controller configured to determine an air stream temperature and an air stream flow rate necessary to establish the desired heat supply rate for the sensitive portion and provide a comfortable thermal environment by thermally isolating the occupant from the ambient vehicle cabin temperature. The system may include a sensor to determine the location of the sensitive portion. The nozzle may include a thermoelectric device to heat or cool the air stream. |
FILED | Tuesday, April 10, 2012 |
APPL NO | 13/442961 |
ART UNIT | 3749 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/00742 (20130101) Original (OR) Class B60H 1/00871 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458115 | Pagoria et al. |
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FUNDED BY |
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APPLICANT(S) | Philip F. Pagoria (Livermore, California); Mao Xi Zhang (Mountain House, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Philip F. Pagoria (Livermore, California); Mao Xi Zhang (Mountain House, California) |
ABSTRACT | A method for synthesizing a pyrazine-containing material according to one embodiment includes contacting an iminodiacetonitrile derivative with a base and a reagent selected from a group consisting of hydroxylamine, a hydroxylamine salt, an aliphatic primary amine, a secondary amine, an aryl-substituted alkylamine a heteroaryl-substituted alkyl amine, an alcohol, an alkanolamine and an aryl alcoholamine. Additional methods and several reaction products are presented. |
FILED | Monday, April 20, 2009 |
APPL NO | 12/426774 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 241/20 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458191 | Chromy et al. |
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FUNDED BY |
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APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Brett A. Chromy (Danville, California); Paul Henderson (Dublin, California); Paul D. Hoeprich, Jr. (Pleasanton, California) |
ABSTRACT | Provided herein are methods and systems for assembling, solubilizing and/or purifying a membrane associated protein in a nanolipoprotein particle, which comprise a temperature transition cycle performed in presence of a detergent, wherein during the temperature transition cycle the nanolipoprotein components are brought to a temperature above and below the gel to liquid crystalling transition temperature of the membrane forming lipid of the nanolipoprotein particle. |
FILED | Friday, November 07, 2014 |
APPL NO | 14/536513 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 1/145 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/02 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/799 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458385 | Gordon |
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FUNDED BY |
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APPLICANT(S) | FIELD UPGRADING LIMITED (Calgary, Canada) |
ASSIGNEE(S) | FIELD UPGRADING LIMITED (Calgary, Canada) |
INVENTOR(S) | John Howard Gordon (Salt Lake City, Utah) |
ABSTRACT | A method that combines the oil retorting process (or other process needed to obtain/extract heavy oil or bitumen) with the process for upgrading these materials using sodium or other alkali metals. Specifically, the shale gas or other gases that are obtained from the retorting/extraction process may be introduced into the upgrading reactor and used to upgrade the oil feedstock. Also, the solid materials obtained from the reactor may be used as a fuel source, thereby providing the heat necessary for the retorting/extraction process. Other forms of integration are also disclosed. |
FILED | Friday, July 12, 2013 |
APPL NO | 13/940336 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 53/06 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/002 (20130101) Original (OR) Class C10G 1/02 (20130101) C10G 9/02 (20130101) C10G 19/067 (20130101) C10G 19/073 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458389 | Schabron et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Wyoming Research Corporation (Laramie, Wyoming) |
ASSIGNEE(S) | The University of Wyoming Research Corporation (Laramie, Wyoming) |
INVENTOR(S) | John F. Schabron (Laramie, Wyoming); Joseph F. Rovani, Jr. (Laramie, Wyoming) |
ABSTRACT | Disclosed herein is a method of estimating a property of a hydrocarbon comprising the steps of: preparing a liquid sample of a hydrocarbon, the hydrocarbon having asphaltene fractions therein; precipitating at least some of the asphaltenes of a hydrocarbon from the liquid sample with one or more precipitants in a chromatographic column; dissolving at least two of the different asphaltene fractions from the precipitated asphaltenes during a successive dissolution protocol; eluting the at least two different dissolved asphaltene fractions from the chromatographic column; monitoring the amount of the fractions eluted from the chromatographic column; using detected signals to calculate a percentage of a peak area for a first of the asphaltene fractions and a peak area for a second of the asphaltene fractions relative to the total peak areas, to determine a parameter that relates to the property of the hydrocarbon; and estimating the property of the hydrocarbon. |
FILED | Friday, January 10, 2014 |
APPL NO | 14/152661 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 7/12 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458482 | Bals et al. |
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FUNDED BY |
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APPLICANT(S) | THE MICHIGAN BIOTECHNOLOGY INSTITUTE (Lansing, Michigan); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
ASSIGNEE(S) | THE MICHIGAN BIOTECHNOLOGY INSTITUTE (Lansing, Michigan); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
INVENTOR(S) | Bryan Bals (East Lansing, Michigan); Farzaneh Teymouri (Okemos, Michigan); Timothy J. Campbell (East Lansing, Michigan); Bruce E. Dale (Mason, Michigan) |
ABSTRACT | A method is provided in which pretreated and densified cellulosic biomass particulates can be hydrolyzed at a high solids loading rate as compared with the solids loading rate of loose hydrolysable cellulosic biomass fibers. The resulting high concentration sugar-containing stream can be easily converted to biofuels or to an entire suite of other useful bioproducts. |
FILED | Monday, December 22, 2014 |
APPL NO | 14/579377 |
ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2201/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458483 | Quinlan et al. |
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FUNDED BY |
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APPLICANT(S) | Novozymes, Inc. (Davis, California) |
ASSIGNEE(S) | NOVOZYMES, Inc. (Davis, California) |
INVENTOR(S) | Jason Quinlan (Woodland, California); Feng Xu (Davis, California); Matthew Sweeney (Sacramento, California) |
ABSTRACT | The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a bicyclic compound. The present invention also relates to methods of using the compositions. |
FILED | Friday, May 15, 2015 |
APPL NO | 14/713751 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/28 (20130101) C12P 7/40 (20130101) C12P 13/04 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2203/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458732 | McMahan et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Kevin Weston McMahan (Greer, South Carolina); Carl Gerard Schott (Simpsonville, South Carolina); Clint Luigie Ingram (Simpsonville, South Carolina); Gunnar Leif Siden (Greenville, South Carolina); Sylvain Pierre (Greer, South Carolina) |
ABSTRACT | Transition duct assemblies for turbine systems and turbomachines are provided. In one embodiment, a transition duct assembly includes a plurality of transition ducts disposed in a generally annular array and comprising a first transition duct and a second transition duct. Each of the plurality of transition ducts includes an inlet, an outlet, and a passage extending between the inlet and the outlet and defining a longitudinal axis, a radial axis, and a tangential axis. The outlet of each transition duct is offset from the inlet along the longitudinal axis and the tangential axis. The transition duct assembly further includes an aerodynamic structure defined by the passages of the first transition duct and the second transition duct. The aerodynamic structure includes a pressure side, a suction side, and a trailing edge, the trailing edge having a modified aerodynamic contour. |
FILED | Friday, October 25, 2013 |
APPL NO | 14/063358 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/141 (20130101) F01D 9/023 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/122 (20130101) F05D 2250/71 (20130101) F05D 2250/182 (20130101) F05D 2250/183 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458838 | Sakadjian et al. |
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FUNDED BY |
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APPLICANT(S) | Babcock and Wilcox Power Generation Group, Inc. (Barberton, Ohio) |
ASSIGNEE(S) | The Babcock and Wilcox Company (Barberton, Ohio) |
INVENTOR(S) | Bartev B Sakadjian (North Canton, Ohio); Thomas J Flynn (North Canton, Ohio); Shengteng Hu (Copley, Ohio); Luis G Velazquez-Vargas (Copley, Ohio); Mikhail Maryamchik (Fairlawn, Ohio) |
ABSTRACT | A power plant includes a solar receiver heating solid particles, a standpipe receiving solid particles from the solar receiver, a pressurized heat exchanger heating working fluid by heat transfer through direct contact with heated solid particles flowing out of the bottom of the standpipe, and a flow path for solid particles from the bottom of the standpipe into the pressurized heat exchanger that is sealed by a pressure P produced at the bottom of the standpipe by a column of heated solid particles of height H. The flow path may include a silo or surge tank comprising a pressure vessel connected to the bottom of the standpipe, and a non-mechanical valve. The power plant may further include a turbine driven by heated working fluid discharged from the pressurized heat exchanger, and a compressor driven by the turbine. |
FILED | Thursday, July 17, 2014 |
APPL NO | 14/333940 |
ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 1/05 (20130101) F02C 1/06 (20130101) F02C 1/10 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 6/04 (20130101) F03G 6/06 (20130101) F03G 6/064 (20130101) Original (OR) Class F03G 6/065 (20130101) F03G 6/067 (20130101) F03G 6/068 (20130101) F03G 2006/008 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/48 (20130101) F24J 2/4649 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/46 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458989 | Hsu et al. |
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FUNDED BY |
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APPLICANT(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Cambridge, Massachusetts); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Cambridge, Massachusetts); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | Disclosed herein are transparent color displays with nanoparticles made with nonlinear materials and/or designed to exhibit optical resonances. These nanoparticles are embedded in or hosted on a transparent substrate, such as a flexible piece of clear plastic or acrylic. Illuminating the nanoparticles with invisible light (e.g., infrared or ultraviolet light) causes them to emit visible light. For example, a rare-earth doped nanoparticle may emit visible light when illuminated simultaneoulsy with a first infrared beam at a first wavelength λ1 and a second infrared beam at a second wavelength λ2. And a frequency-doubling nanoparticle may emit visible light when illuminated with a single infrared beam at the nanoparticle's resonant frequency. Selectively addressing these nanoparticles with appropiately selected pump beams yields visible light emitted from the nanoparticles hosted by the transparent substrate in a desired pattern. |
FILED | Monday, December 30, 2013 |
APPL NO | 14/143558 |
ART UNIT | 2875 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 9/08 (20130101) F21V 9/12 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/19 (20130101) G02F 1/0126 (20130101) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 13/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459024 | Ghasemi et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Hadi Ghasemi (Houston, Texas); Amy Marie Marconnet (West Lafayette, Indiana); Gang Chen (Carlisle, Massachusetts); George Wei Ni (Ann Arbor, Michigan) |
ABSTRACT | A localized heating structure, and method of forming same, for use in solar systems includes a thermally insulating layer having interconnected pores, a density of less than about 3000 kg/m3, and a hydrophilic surface, and an expanded carbon structure adjacent to the thermally insulating layer. The expanded carbon structure has a porosity of greater than about 80% and a hydrophilic surface. |
FILED | Saturday, September 06, 2014 |
APPL NO | 14/479307 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 5/32 (20130101) B32B 2266/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2205/026 (20130101) C08J 2383/02 (20130101) Compositions of Macromolecular Compounds C08L 83/02 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/28 (20130101) F24J 2/42 (20130101) F24J 2/48 (20130101) F24J 2/515 (20130101) Original (OR) Class F24J 2002/469 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/44 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) Y10T 428/249967 (20150401) Y10T 428/249969 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459161 | Galambos et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Paul C. Galambos (Albuquerque, New Mexico); Thomas B. Crenshaw (Albuquerque, New Mexico); Erik E. Nishida (Albuquerque, New Mexico); Damon J. Burnett (Sandia Park, New Mexico); Jeffrey W. Lantz (Albuquerque, New Mexico) |
ABSTRACT | The various technologies presented herein relate to a sensor for measurement of high forces and/or high load shock rate(s), whereby the sensor utilizes silicon as the sensing element. A plate of Si can have a thinned region formed therein on which can be formed a number of traces operating as a Wheatstone bridge. The brittle Si can be incorporated into a layered structure comprising ductile and/or compliant materials. The sensor can have a washer-like configuration which can be incorporated into a nut and bolt configuration, whereby tightening of the nut and bolt can facilitate application of a compressive preload upon the sensor. Upon application of an impact load on the bolt, the compressive load on the sensor can be reduced (e.g., moves towards zero-load), however the magnitude of the preload can be such that the load on the sensor does not translate to tensile stress being applied to the sensor. |
FILED | Wednesday, June 01, 2016 |
APPL NO | 15/170355 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Original (OR) Class G01L 5/0028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459848 | Horie et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Michihiro Horie (Saitama, Japan); Hiroshi H. Horii (Tokyo, Japan); Kiyokuni Kawachiya (Kanagawa, Japan); Mikio Takeuchi (Kanagawa, Japan) |
ABSTRACT | Methods and a system are provided. A method includes implementing a function, which a compiler for a first language does not have, using a compiler for a second language. The implementing step includes generating, by the compiler for the first language, a first abstract syntax tree. The implementing step further includes converting, by a converter, the first abstract syntax tree to a second abstract syntax tree of the compiler for the second language using a conversion table from data representation types in the first language to data representation types in the second language. When a compilation error occurs, the implementing step also includes generating a special node for error processing in the second abstract syntax tree and storing an error token in the special node. When unparsing, the implementing step additionally includes outputting the error token, in the form of source code written in the first language. |
FILED | Friday, May 29, 2015 |
APPL NO | 14/725219 |
ART UNIT | 2191 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 8/427 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459917 | Archer et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Amanda E. Randles (Cambridge, Massachusetts); Joseph D. Ratterman (Seattle, Washington); Brian E. Smith (Knoxville, Tennessee) |
ABSTRACT | Methods, apparatus, and products are disclosed for thread selection during context switching on a plurality of compute nodes that includes: executing, by a compute node, an application using a plurality of threads of execution, including executing one or more of the threads of execution; selecting, by the compute node from a plurality of available threads of execution for the application, a next thread of execution in dependence upon power characteristics for each of the available threads; determining, by the compute node, whether criteria for a thread context switch are satisfied; and performing, by the compute node, the thread context switch if the criteria for a thread context switch are satisfied, including executing the next thread of execution. |
FILED | Monday, March 04, 2013 |
APPL NO | 13/783968 |
ART UNIT | 2195 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 1/329 (20130101) G06F 1/3203 (20130101) G06F 9/46 (20130101) G06F 9/48 (20130101) G06F 9/4893 (20130101) Original (OR) Class G06F 9/5027 (20130101) G06F 9/5094 (20130101) G06F 2209/5018 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/142 (20130101) Y02B 60/144 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459934 | Archer et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Joseph D. Ratterman (Seattle, Washington); Brian E. Smith (Knoxville, Tennessee) |
ABSTRACT | Performing a global barrier operation in a parallel computer that includes compute nodes coupled for data communications, where each compute node executes tasks, with one task on each compute node designated as a master task, including: for each task on each compute node until all master tasks have joined a global barrier: determining whether the task is a master task; if the task is not a master task, joining a single local barrier; if the task is a master task, joining the global barrier and the single local barrier only after all other tasks on the compute node have joined the single local barrier. |
FILED | Wednesday, November 21, 2012 |
APPL NO | 13/683726 |
ART UNIT | 2195 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/46 (20130101) G06F 9/52 (20130101) G06F 9/522 (20130101) Original (OR) Class G06F 9/542 (20130101) G06F 9/546 (20130101) G06F 15/17318 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460321 | Brocato |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Robert W. Brocato (Sandia Park, New Mexico) |
ABSTRACT | An unpowered signal receiver and a method for signal reception detects and responds to very weak signals using pyroelectric devices as impedance transformers and/or demodulators. In some embodiments, surface acoustic wave devices (SAW) are also used. Illustrative embodiments include satellite and long distance terrestrial communications applications. |
FILED | Wednesday, August 20, 2014 |
APPL NO | 14/464634 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/34 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/0008 (20130101) Original (OR) Class G06K 7/10079 (20130101) G06K 19/0723 (20130101) Demodulation or Transference of Modulation From One Carrier to Another H03D 1/00 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/56 (20130101) H03H 9/64 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460865 | Worsley et al. |
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FUNDED BY |
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APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Marcus A. Worsley (Hayward, California); Theodore F. Baumann (Discovery Bay, California); Joe H. Satcher, Jr. (Patterson, California) |
ABSTRACT | Disclosed here is a device comprising a porous carbon aerogel or composite thereof as an energy storage material, catalyst support, sensor or adsorbent, wherein the porous carbon aerogel comprises a network of interconnected struts comprising carbon nanotube bundles covalently crosslinked by graphitic carbon nanoparticles, wherein the carbon nanotubes account for 5 to 95 wt. % of the aerogel and the graphitic carbon nanoparticles account for 5 to 95 wt. % of the aerogel, and wherein the aerogel has an electrical conductivity of at least 10 S/m and is capable of withstanding strains of more than 10% before fracture. |
FILED | Thursday, May 12, 2016 |
APPL NO | 15/152801 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/26 (20130101) H01G 11/36 (20130101) H01G 11/38 (20130101) H01G 11/56 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/583 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/752 (20130101) Y10S 977/948 (20130101) Y10S 977/953 (20130101) Y10S 977/962 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460884 | Hopwood et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey A. Hopwood (Needham, Massachusetts); Chen Wu (Shanghai, China PRC); Alan R. Hoskinson (Watertown, Massachusetts); Sameer Sonkusale (Arlington, Massachusetts) |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | Jeffrey A. Hopwood (Needham, Massachusetts); Chen Wu (Shanghai, China PRC); Alan R. Hoskinson (Watertown, Massachusetts); Sameer Sonkusale (Arlington, Massachusetts) |
ABSTRACT | A microplasma generator includes first and second conductive resonators disposed on a first surface of a dielectric substrate. The first and second conductive resonators are arranged in line with one another with a gap defined between a first end of each resonator. A ground plane is disposed on a second surface of the dielectric substrate and a second end of each of the first and second resonators is coupled to the ground plane. A power input connector is coupled to the first resonator at a first predetermined distance from the second end chosen as a function of the impedance of the first conductive resonator. A microplasma generating array includes a number of resonators in a dielectric material substrate with one end of each resonator coupled to ground. A micro-plasma is generated at the non-grounded end of each resonator. The substrate includes a ground electrode and the microplasmas are generated between the non-grounded end of the resonator and the ground electrode. The coupling of each resonator to ground may be made through controlled switches in order to turn each resonator off or on and therefore control where and when a microplasma will be created in the array. |
FILED | Thursday, July 26, 2012 |
APPL NO | 14/235510 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 7/46 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/2406 (20130101) H05H 2001/2425 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461185 | Nair et al. |
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FUNDED BY |
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APPLICANT(S) | Enki Technology, Inc. (San Jose, California) |
ASSIGNEE(S) | Enki Technology, Inc. (San Jose, California) |
INVENTOR(S) | Vinod Nair (San Jose, California); Brenor L. Brophy (San Jose, California) |
ABSTRACT | Disclosed herein is a coated glass element including a glass component and a coating adhered to the glass component through siloxane linkages, the coating having at least one of an anti-reflective property, a high abrasion resistance property and a hydrophobic property, wherein the coating comprises a dried gel formed from at least one hydrolyzed alkoxysilane-based sol and at least one hydrolyzed organosilane-based sol. |
FILED | Monday, September 14, 2015 |
APPL NO | 14/852872 |
ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/007 (20130101) C03C 17/30 (20130101) C03C 2203/27 (20130101) C03C 2217/20 (20130101) C03C 2217/76 (20130101) C03C 2217/78 (20130101) C03C 2217/94 (20130101) C03C 2217/425 (20130101) C03C 2217/732 (20130101) C03C 2218/113 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/24 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/006 (20130101) C09D 5/1662 (20130101) C09D 183/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02168 (20130101) Original (OR) Class H01L 31/022466 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115) Y10T 428/31612 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461191 | Wernsman et al. |
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FUNDED BY |
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APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Bernard Wernsman (Jefferson Hills, Pennsylvania); Joseph N. Fiedor (Jefferson Hills, Pennsylvania); Lawrence G. Irr (Trafford, Pennsylvania); Marc N. Palmisiano (Pittsburgh, Pennsylvania) |
ABSTRACT | A back surface reflector (BSR) is described. The BSR includes a reflecting layer, a substrate and an adhesion layer between the reflecting layer and the substrate. The adhesion layer includes 3-mercaptopropyl (trimethoxy) silane (a.k.a. Merc). |
FILED | Monday, February 24, 2014 |
APPL NO | 14/187666 |
ART UNIT | 1756 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/08 (20130101) G02B 5/0284 (20130101) G02B 5/0808 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0406 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461278 | Gaikwad et al. |
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FUNDED BY |
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APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
INVENTOR(S) | Abhinav Gaikwad (Berkeley, California); Dan Steingart (Princeton, New Jersey) |
ABSTRACT | Disclosed in this specification is a method for providing a stretchable power source and corresponding device. The device has at least two stretchable fabrics with silver-coated fibers. Each fabric has cathodic and anodic materials, respectively, deposited between the fibers. The fibers are sealed with an elastomeric pouch having an electrolyte. The stretchable power source has substantially no change in discharge capacity when stretched from 0% strain to 100% strain. |
FILED | Wednesday, April 10, 2013 |
APPL NO | 13/860226 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/021 (20130101) H01M 2/0207 (20130101) Original (OR) Class H01M 2/0275 (20130101) H01M 4/75 (20130101) H01M 4/667 (20130101) H01M 4/668 (20130101) H01M 6/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461328 | Lines |
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FUNDED BY |
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APPLICANT(S) | Michael T Lines (South Windsor, Connecticut) |
ASSIGNEE(S) | Ballard Power Systems Inc. (Burnaby, Canada) |
INVENTOR(S) | Michael T Lines (South Windsor, Connecticut) |
ABSTRACT | The bootstrap start-up system (42) achieves an efficient start-up of the power plant (10) that minimizes formation of soot within a reformed hydrogen rich fuel. A burner (48) receives un-reformed fuel directly from the fuel supply (30) and combusts the fuel to heat cathode air which then heats an electrolyte (24) within the fuel cell (12). A dilute hydrogen forming gas (68) cycles through a sealed heat-cycling loop (66) to transfer heat and generated steam from an anode side (32) of the electrolyte (24) through fuel processing system (36) components (38, 40) and back to an anode flow field (26) until fuel processing system components (38, 40) achieve predetermined optimal temperatures and steam content. Then, the heat-cycling loop (66) is unsealed and the un-reformed fuel is admitted into the fuel processing system (36) and anode flow (26) field to commence ordinary operation of the power plant (10). |
FILED | Monday, August 20, 2012 |
APPL NO | 13/589281 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/02 (20130101) H01M 8/04 (20130101) H01M 8/22 (20130101) Original (OR) Class H01M 8/2465 (20130101) H01M 8/2465 (20130101) H01M 8/2483 (20160201) H01M 8/04253 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461523 | Shoykhet |
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FUNDED BY |
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APPLICANT(S) | Baldor Electric Company (Fort Smith, Arkansas) |
ASSIGNEE(S) | Baldor Electric Company (Fort Smith, Arkansas) |
INVENTOR(S) | Boris A. Shoykhet (Beachwood, Ohio) |
ABSTRACT | An electro-dynamic machine has a rotor and stator with a gap therebetween. The machine has a frame defining a hollow interior with end cavities on axially opposite ends of the frame. A gas circulating system has an inlet that supplies high pressure gas to the frame interior and an outlet to collect gas passing therethrough. A liquid coolant circulating system has an inlet that supplies coolant to the frame interior and an outlet that collects coolant passing therethrough. The coolant inlet and gas inlet are generally located on the frame in a manner to allow coolant from the coolant inlet to flow with gas from the gas inlet to the gap. The coolant outlet and gas outlet are generally located on the frame in a manner to allow the coolant to be separated from the gas with the separated coolant and gas collected for circulation through their respective circulating systems. |
FILED | Thursday, December 12, 2013 |
APPL NO | 14/104724 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Dynamo-electric Machines H02K 9/00 (20130101) Original (OR) Class H02K 9/12 (20130101) H02K 9/19 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 09456794 | Carpenter et al. |
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FUNDED BY |
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APPLICANT(S) | Colin M Carpenter (Redwood City, California); Lei Xing (Palo Alto, California); Guillem Pratx (Mountain View, California); Conroy Ghin Chee Sun (Sunnyvale, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Colin M Carpenter (Redwood City, California); Lei Xing (Palo Alto, California); Guillem Pratx (Mountain View, California); Conroy Ghin Chee Sun (Sunnyvale, California) |
ABSTRACT | Molecular imaging of radioluminescent nanoparticle probes injected into biological tissue is performed by irradiated the tissue with ionizing radiation to induce radioluminescence at optical wavelengths, preferably at predetermined near infrared wavelengths. The optical light is detected and processed to determine a spatial distribution of the probes. The radioluminescent nanoparticles may be inorganic or organic phosphors, scintillators, or quantum dots. Imaging systems realizing this technique include tomographic systems using an x-ray beam to sequentially irradiate selected regions, systems with a radioactive source producing the ionizing radiation from outside the tissue, such as with a beam, or inside the tissue, such as with an endoscope or injected radiopharmaceutical. The optical signals may be detected by a photodetector array external to the tissue, a photodetector integrated with an endoscope or mammographic paddle, integrated into a capsule endoscope, or an array positioned near the biological tissue. |
FILED | Friday, April 08, 2011 |
APPL NO | 13/066190 |
ART UNIT | 3777 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/425 (20130101) A61B 6/508 (20130101) A61B 6/4057 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09457041 | Kulkarni et al. |
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FUNDED BY |
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APPLICANT(S) | Prajakta S. Kulkarni (Fargo, North Dakota); Manas K. Haldar (Fargo, North Dakota); Sanku Mallik (West Fargo, North Dakota); D. K. Srivastava (Reilies Acres, North Dakota) |
ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
INVENTOR(S) | Prajakta S. Kulkarni (Fargo, North Dakota); Manas K. Haldar (Fargo, North Dakota); Sanku Mallik (West Fargo, North Dakota); D. K. Srivastava (Reilies Acres, North Dakota) |
ABSTRACT | Provided herein are nanoparticles that include a lipid layer and a compartment surrounded by the lipid layer. The lipid layer may include a lipid and a lipoprotein. The lipid may include a POPE lipid covalently attached to a hydrophilic polymer by a disulfide bond. The lipoprotein may include a trigger protein. The concentration of the first lipid may be between 1 mol % and 30 mol %. The disulfide bond of the first lipid is stable under conditions that include 10% human serum and is broken under conditions that include 50 micromolar glutathione. The hydrophilic polymer may include a PEG molecule. The trigger protein may include an amino acid repeat region, such as (GPX)n. The trigger protein may include a peptide bond that is cleaved by a gelatinase (e.g., gelatinase-B protease), or a member of the ADAM family of proteases (e.g., ADAM10 protease). Also provided are methods of using the nanoparticles. |
FILED | Friday, June 19, 2015 |
APPL NO | 14/744705 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1271 (20130101) A61K 31/7068 (20130101) Original (OR) Class A61K 49/0093 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458086 | Patel et al. |
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FUNDED BY |
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APPLICANT(S) | Niketa A. Patel (Land O'Lakes, Florida); Rekha S. Patel (Tampa, Florida); Kirpal S. Bisht (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (A Florida Non-Profit Corporation) (Tampa, Florida); The United States of America as Represented by the Department of Veterans Affairs Office of General Counsel PSG IV (024) (Washington, District of Columbia) |
INVENTOR(S) | Niketa A. Patel (Land O'Lakes, Florida); Rekha S. Patel (Tampa, Florida); Kirpal S. Bisht (Tampa, Florida) |
ABSTRACT | Modified stilbenoids and formulations thereof are provided. The modified stilbenoids can include one or more amino or amino-alkyl substituents. The formulation can be for the treatment or prevention of obesity and the modified stilbenoid present in an effective amount to alleviate or prevent the onset of one or more symptoms of obesity. Methods of making the modified stilbenoids and formulations thereof are provided. Methods are provided for treating a subject with a modified stilbenoid in an effective amount to alleviate or prevent one or more symptoms associated with diabetes, cardiovascular disease, high blood pressure, deep vein thrombosis, osteoarthritis, obstructive sleep apnea, cancer, and non-alcoholic fatty liver disease. The administration of the modified stilbenoids can result in decreased levels of PKCδII, PKCδVIII, substantially unaltered expression of PKCδI; a decreased number of adipocytes; increased weight and/or fat loss; or a combination thereof. |
FILED | Wednesday, July 02, 2014 |
APPL NO | 14/322236 |
ART UNIT | 1671 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 215/50 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458185 | Tilley et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | T. Don Tilley (Orinda, California); Jian Yang (Houston, Texas) |
ABSTRACT | In various embodiments, the invention provides phosphine ligand supported first row metal catalysts with surprising and efficacious catalytic activity for hydrosilylation of pi-bonded substrates. Also provided are methods of using the catalysts of the invention to prepare hydrosilylated compounds. |
FILED | Monday, February 11, 2013 |
APPL NO | 14/377833 |
ART UNIT | 1671 — Organic Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/22 (20130101) B01J 31/1895 (20130101) B01J 31/2295 (20130101) B01J 2231/323 (20130101) B01J 2531/847 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/004 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0809 (20130101) C07F 7/0829 (20130101) C07F 7/0896 (20130101) C07F 15/045 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458449 | Kirshenbaum et al. |
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FUNDED BY |
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APPLICANT(S) | Kent Kirshenbaum (New York, New York); Paul Levine (Brooklyn, New York); Timothy Craven (Randolph, New Jersey) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Kent Kirshenbaum (New York, New York); Paul Levine (Brooklyn, New York); Timothy Craven (Randolph, New Jersey) |
ABSTRACT | Novel hybrid polymers are disclosed that have a structure represented by the following wherein Abiotic oligomer, Polypeptide, X, Y, and R1 are as described herein. The methods to prepare the hybrid polymers via novel oxazolidinyl compounds are also described. |
FILED | Tuesday, May 20, 2014 |
APPL NO | 14/282228 |
ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 1/13 (20130101) C07K 1/026 (20130101) C07K 5/081 (20130101) C07K 5/0806 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458453 | Firnberg et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Elad Firnberg (Baltimore, Maryland); Marc Alan Ostermeier (Baltimore, Maryland) |
ABSTRACT | The presently disclosed subject matter relates to modified Kunkel mutagenesis methods that use a thermostable DNA polymerase and a thermostable DNA ligase. |
FILED | Wednesday, June 12, 2013 |
APPL NO | 14/407683 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/102 (20130101) C12N 15/1031 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458989 | Hsu et al. |
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FUNDED BY |
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APPLICANT(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Cambridge, Massachusetts); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Cambridge, Massachusetts); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | Disclosed herein are transparent color displays with nanoparticles made with nonlinear materials and/or designed to exhibit optical resonances. These nanoparticles are embedded in or hosted on a transparent substrate, such as a flexible piece of clear plastic or acrylic. Illuminating the nanoparticles with invisible light (e.g., infrared or ultraviolet light) causes them to emit visible light. For example, a rare-earth doped nanoparticle may emit visible light when illuminated simultaneoulsy with a first infrared beam at a first wavelength λ1 and a second infrared beam at a second wavelength λ2. And a frequency-doubling nanoparticle may emit visible light when illuminated with a single infrared beam at the nanoparticle's resonant frequency. Selectively addressing these nanoparticles with appropiately selected pump beams yields visible light emitted from the nanoparticles hosted by the transparent substrate in a desired pattern. |
FILED | Monday, December 30, 2013 |
APPL NO | 14/143558 |
ART UNIT | 2875 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 9/08 (20130101) F21V 9/12 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/19 (20130101) G02F 1/0126 (20130101) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 13/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459163 | Sirbuly et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Donald J. Sirbuly (Carlsbad, California); Sadik C. Esener (Solana Beach, California); Ilsun Yoon (San Diego, California) |
ABSTRACT | Methods, structures, devices and systems are disclosed for implementing a fiber optic force sensing transducer. In one aspect, an exemplary fiber optic force sensing transducer device includes an optical fiber coated by at least one layer of a polyelectrolyte material that utilizes the movement of optical structures coupled to the external polyelectrolyte layer in an evanescent field produced by the optical fiber to detect forces imposing on the fiber. In one aspect, an optical sensing device includes an optical waveguide that internally guides light, one or more layers formed outside the optical waveguide within an evanescent field of the guided light in the optical waveguide, and one or more optical structures coupled to the one or more layers in the evanescent field to emit light based on interaction with the evanescent field to indicate a position of an optical structure relative to an external surface of the optical waveguide. |
FILED | Wednesday, January 22, 2014 |
APPL NO | 14/762792 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/242 (20130101) G01L 1/243 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459171 | Pan et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Tingrui Pan (Woodland, California); Baoqing Nie (Davis, California); Siyuan Xing (Davis, California); James D. Brandt (Los Angeles, California) |
ABSTRACT | A pressure sensing apparatus which utilizes an electrolytic droplet retained between a first and second sensing electrode within a housing. Contact between the electrolyte droplet and the electrodes form electric double layers (EDL) having interfacial EDL capacitance proportional to interface contact area which varies in response to mechanical pressure applied to deform exterior portions of the housing. The electrolyte contains a sufficient percentage of glycerol to prevent evaporative effects. Preferably, the sensing electrodes are modified with depressions, hydrophilic and/or hydrophobic portions to increase central anchoring of the electrolyte droplet within the housing. The inventive pressure sensor provides high sensitivity and resolution which is beneficial to numerous applications, and is particularly well-suited for medical sensing applications. |
FILED | Tuesday, October 27, 2015 |
APPL NO | 14/923956 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/0072 (20130101) Original (OR) Class G01L 9/0075 (20130101) G01L 9/0092 (20130101) G01L 9/0095 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459258 | Tang et al. |
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FUNDED BY |
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APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana); TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORP. (Indianapolis, Indiana); TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
INVENTOR(S) | Haixu Tang (Bloomington, Indiana); Yehia S. Mechref (Lubbock, Texas) |
ABSTRACT | Illustrative embodiments of methods and apparatus for identifying one or more intact glycopeptides in a sample are disclosed. According to one illustrative embodiment, a method may comprise receiving data representing a plurality of mass spectra obtained from mass spectrometry of the sample, scoring data representing each of the plurality of mass spectra against data associated with target glycopeptides, and identifying one or more intact glycopeptides in the sample based at least in part on the scoring of the data representing each of the plurality of mass spectra. |
FILED | Tuesday, May 21, 2013 |
APPL NO | 14/402686 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2440/38 (20130101) Electric Digital Data Processing G06F 19/70 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459308 | Tatcho et al. |
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FUNDED BY |
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APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
INVENTOR(S) | Passinam Tatcho (Tallahassee, Florida); Mischa Steurer (Crawfordville, Florida); Hui Li (Tallahassee, Florida) |
ABSTRACT | The present invention provides a system to ensure that distributed resources of a power distribution system remain connected to the circuitry of the power distribution system when a fault occurs at a distributed resource node to assist in identifying the location of the fault by continuing to inject current from the distributed resources into the distribution system, wherein at least one of the distributed resources comprises a controllable voltage source converter. |
FILED | Tuesday, December 08, 2015 |
APPL NO | 14/962774 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/00 (20130101) G01R 31/40 (20130101) G01R 31/086 (20130101) Original (OR) Class G01R 31/088 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/00 (20130101) H02J 2001/002 (20130101) H02J 2001/004 (20130101) H02J 2001/006 (20130101) H02J 2001/008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09459685 | Flikkema |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on behalf of Northern Arizona University (Flagstaff, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on behalf of Northern Arizona University (Flagstaff, Arizona) |
INVENTOR(S) | Paul G. Flikkema (Flagstaff, Arizona) |
ABSTRACT | A system for optimizing energy efficiency of an embedded system. A hardware abstraction layer (HAL) is coupled to hardware of an embedded system. An energy hardware abstraction layer (eHAL) couples to the hardware and to the HAL. A hypervisor couples to the HAL and to the eHAL. One or more applications couple to the hypervisor, the HAL and the eHAL. The eHAL measures energy use of the embedded system, constructs a model of energy use of the embedded system and, using the model, determines how to one of reduce and minimize energy use of the embedded system. The hypervisor is configured to alter one or more hardware parameters to one of reduce and minimize energy use of the embedded system as the embedded system performs one or more tasks. In implementations a real time operating system (RTOS) is coupled to the one or more applications and to the hypervisor. |
FILED | Tuesday, December 10, 2013 |
APPL NO | 14/102369 |
ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/3234 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460478 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Junshan Zhang (Chandler, Arizona); Miao He (Tempe, Arizona); Lei Yang (Tempe, Arizona); Vijay Vittal (Scottsdale, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Junshan Zhang (Chandler, Arizona); Miao He (Tempe, Arizona); Lei Yang (Tempe, Arizona); Vijay Vittal (Scottsdale, Arizona) |
ABSTRACT | Systems and methods for managing electricity of an electrical supply grid electrically connected to a wind farm are disclosed. Some systems and methods may include identifying relationships among a plurality of turbines in the wind farm with a minimum spanning tree, calculating a power output relationship among the plurality of turbines with the minimum spanning tree, creating a finite state space Markov chain forecast model for the plurality of turbines in the wind farm, predicting a power output of the wind farm with the finite state space Markov chain forecast model, and modifying at least one of a generation of electricity and a distribution of electricity based on the predicted power output of the wind farm. Also disclosed are systems and methods for predicting the power output of a wind farm. |
FILED | Tuesday, December 17, 2013 |
APPL NO | 14/109586 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 50/06 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/386 (20130101) H02J 2003/007 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/763 (20130101) Y02E 60/76 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Y04S 40/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09460863 | Li |
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FUNDED BY |
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APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | Xiaodong Li (Irmo, South Carolina) |
ABSTRACT | An asymmetric supercapacitor is described. The supercapacitor includes a first electrode, a second electrode, a thin film separator, and an electrolyte. The first electrode comprises functionalized cellulose fiber and the second electrode comprises functionalized cellulose fiber and metal oxide. |
FILED | Friday, April 19, 2013 |
APPL NO | 13/866103 |
ART UNIT | 2848 — Electrical Circuits and Systems |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/04 (20130101) H01G 11/30 (20130101) Original (OR) Class H01G 11/40 (20130101) H01G 11/46 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/43 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461203 | Steinhardt et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | Paul J. Steinhardt (Princeton, New Jersey); Salvatore Torquato (Princeton, New Jersey); Marian Florescu (Guildford, United Kingdom) |
ABSTRACT | The invention provides an article of manufacture, and methods of designing and making the article. The article permits or prohibits waves of energy, especially photonic/electromagnetic energy, to propagate through it, depending on the energy band gaps built into it. The structure of the article may be reduced to a pattern of points having a hyperuniform distribution. The point-pattern may exhibit a crystalline symmetry, a quasicrystalline symmetry or may be aperiodic. In some embodiments, the point pattern exhibits no long-range order. Preferably, the point-pattern is isotropic. In all embodiments, the article has a complete, TE- and TM-optimized band-gap. The extraordinary transmission phenomena found in the disordered hyperuniform photonic structures of the invention find use in optical micro-circuitry (all-optical, electronic or thermal switching of the transmission), near-field optical probing, thermophotovoltaics, and energy-efficient incandescent sources. |
FILED | Monday, November 30, 2015 |
APPL NO | 14/953652 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/16 (20130101) Original (OR) Class H01L 33/0058 (20130101) H01L 33/0095 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461241 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Weigang Wang (Baltimore, Maryland); Chia-Ling Chien (Cockeysviile, Maryland) |
ABSTRACT | A magneto-electronic device includes a first electrode, a second electrode spaced apart from the first electrode, and an electric-field-controllable magnetic tunnel junction arranged between the first electrode and the second electrode. The electric-field-controllable magnetic tunnel junction includes a first ferromagnetic layer, an insulating layer formed on the first ferromagnetic layer, and a second ferromagnetic layer formed on the insulating layer. The first and second ferromagnetic layers have respective first and second magnetic anisotropies that are alignable substantially parallel to each other in a first state and substantially antiparallel in a second state of the electric-field-controllable magnetic tunnel junction. A current of tunneling electrons through the insulating layer is greater in the first state than the second state, and a voltage applied between the first and second electrodes causes a change in at least one of a magnetic anisotropy energy, coercivity or domain wall velocity of at least one of the first and second ferromagnetic layers or a tunneling potential energy barrier through the insulating layer to at least assist in changing the electric-field-controllable magnetic tunnel junction from at least one of the first and second states to the other of the first and second states. |
FILED | Tuesday, September 22, 2015 |
APPL NO | 14/861795 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 11/161 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/3286 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 29/82 (20130101) H01L 43/02 (20130101) H01L 43/08 (20130101) Original (OR) Class H01L 43/10 (20130101) H01L 43/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461481 | Tseng |
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FUNDED BY |
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APPLICANT(S) | QUALCOMM Incorporated (San Diego, California) |
ASSIGNEE(S) | QUALCOMM Incorporated (San Diego, California) |
INVENTOR(S) | Ryan Tseng (Coronado, California) |
ABSTRACT | Systems and methods for feedback control of output power in a wireless power transmitter are disclosed. According to one aspect, one of a voltage level at an input of a wireless power transmit coil and a level of current passing through the wireless power transmit coil are sensed. The wireless power transmitter includes a controller configured to adjust an electrical characteristic of the wireless power transmitter to maintain at least one of the level of current and the voltage level at a constant level. |
FILED | Tuesday, August 18, 2015 |
APPL NO | 14/829135 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 5/005 (20130101) Original (OR) Class H02J 17/00 (20130101) Transmission H04B 5/0037 (20130101) H04B 5/0081 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09462048 | Szalay et al. |
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FUNDED BY |
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APPLICANT(S) | Sandor Szalay (Baltimore, Maryland); Edward Givelberg (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Sandor Szalay (Baltimore, Maryland); Edward Givelberg (Baltimore, Maryland) |
ABSTRACT | A system and method for operating a data-intensive computer is provided. The data-intensive computer includes a processing sub-system formed by a plurality of processing node servers and a database sub-system formed by a plurality of database servers configured to form a collective database in excess of a petabyte of storage. The data-intensive computer also includes an operating system sub-system formed by a plurality of operating system servers that extend a unifying operating system environment across the processing sub-system, the database sub-system, and the operating system sub-system to act as components in a single data-intensive computer. The operating system sub-system is configured to coordinate execution of a single application as distributed processes having at least one of the distributed processes executed on the processing sub-system and at least one of the distributed processes executed on the database sub-system. |
FILED | Thursday, July 23, 2015 |
APPL NO | 14/807550 |
ART UNIT | 2193 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/44 (20130101) G06F 9/466 (20130101) G06F 9/4881 (20130101) G06F 9/5072 (20130101) G06F 17/30864 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 09457009 | Guthrie |
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FUNDED BY |
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APPLICANT(S) | O'neil W. Guthrie (Loma Linda, California) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
INVENTOR(S) | O'neil W. Guthrie (Loma Linda, California) |
ABSTRACT | The invention provides methods for treating auditory impairments in a subject in need of treatment comprising administering to said subject an effective amount of a composition comprising, as an active agent, one or more of a carboxy alkyl ester, a quinic acid derivative, a caffeic acid derivative, a ferulic acid derivative, or a quinic acid lactone or derivative thereof or pharmaceutically acceptable salt thereof and an acceptable carrier or excipient, so as to treat auditory impairments in the subject. |
FILED | Friday, May 31, 2013 |
APPL NO | 13/907590 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/215 (20130101) A61K 31/215 (20130101) A61K 31/216 (20130101) A61K 31/216 (20130101) A61K 31/365 (20130101) Original (OR) Class A61K 31/365 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458086 | Patel et al. |
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FUNDED BY |
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APPLICANT(S) | Niketa A. Patel (Land O'Lakes, Florida); Rekha S. Patel (Tampa, Florida); Kirpal S. Bisht (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (A Florida Non-Profit Corporation) (Tampa, Florida); The United States of America as Represented by the Department of Veterans Affairs Office of General Counsel PSG IV (024) (Washington, District of Columbia) |
INVENTOR(S) | Niketa A. Patel (Land O'Lakes, Florida); Rekha S. Patel (Tampa, Florida); Kirpal S. Bisht (Tampa, Florida) |
ABSTRACT | Modified stilbenoids and formulations thereof are provided. The modified stilbenoids can include one or more amino or amino-alkyl substituents. The formulation can be for the treatment or prevention of obesity and the modified stilbenoid present in an effective amount to alleviate or prevent the onset of one or more symptoms of obesity. Methods of making the modified stilbenoids and formulations thereof are provided. Methods are provided for treating a subject with a modified stilbenoid in an effective amount to alleviate or prevent one or more symptoms associated with diabetes, cardiovascular disease, high blood pressure, deep vein thrombosis, osteoarthritis, obstructive sleep apnea, cancer, and non-alcoholic fatty liver disease. The administration of the modified stilbenoids can result in decreased levels of PKCδII, PKCδVIII, substantially unaltered expression of PKCδI; a decreased number of adipocytes; increased weight and/or fat loss; or a combination thereof. |
FILED | Wednesday, July 02, 2014 |
APPL NO | 14/322236 |
ART UNIT | 1671 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 215/50 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458215 | Lau et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); Loma Linda University (Loma Linda, California) |
ASSIGNEE(S) | Loma Linda University (Loma Linda, California); The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia) |
INVENTOR(S) | Kin-Hing William Lau (Redlands, California); Susan L. Hall (San Bernardino, California); Shin-Tai Chen (Colton, California); Subburaman Mohan (Redlands, California); David J. Baylink (Redlands, California) |
ABSTRACT | The present disclosure provides compositions and methods for increasing bone growth and/or enhancing wound healing, for example, fracture repair. The disclosure provides recombinant nucleic acids useful for promoting bone growth. For example, the disclosure provides recombinant nucleic acids that encode a fibroblast growth factor-2 (FGF-2) analog. The disclosure also provides vectors and cells incorporating these nucleic acids, as well as FGF-2 analogs encode by them. The disclosure also provides a mouse system of bone marrow transplantation and methods for producing as well as methods for using the system. Methods for inducing division and/or inducing differentiation of a hematopoietic stem cell are also provided, as are methods for enhancing bone growth and/or wound repair (for example, fracture repair). |
FILED | Tuesday, May 27, 2014 |
APPL NO | 14/287991 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2207/12 (20130101) A01K 2267/035 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1825 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2799/027 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 09460353 | Rankin et al. |
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FUNDED BY |
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APPLICANT(S) | Arturo L. Rankin (Santa Clarita, California); Larry H. Matthies (Northridge, California); Paolo Bellutta (La Crescenta, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Arturo L. Rankin (Santa Clarita, California); Larry H. Matthies (Northridge, California); Paolo Bellutta (La Crescenta, California) |
ABSTRACT | Systems and methods are disclosed that include automated machine vision that can utilize images of scenes captured by a 3D imaging system configured to image light within the visible light spectrum to detect water. One embodiment includes autonomously detecting water bodies within a scene including capturing at least one 3D image of a scene using a sensor system configured to detect visible light and to measure distance from points within the scene to the sensor system, and detecting water within the scene using a processor configured to detect regions within each of the at least one 3D images that possess at least one characteristic indicative of the presence of water. |
FILED | Friday, September 16, 2011 |
APPL NO | 13/235280 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00805 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461352 | Jung-Kubiak et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Cecile Jung-Kubiak (Pasadena, California); Theodore Reck (Pasadena, California); Goutam Chattopadhyay (Pasadena, California); Jose Vicente Siles Perez (Pasadena, California); Robert H. Lin (Chino, California); Imran Mehdi (South Pasadena, California); Choonsup Lee (La Palma, California); Ken B. Cooper (Glendale, California); Alejandro Peralta (Huntington Beach, California) |
ABSTRACT | A multi-step silicon etching process has been developed to fabricate silicon-based terahertz (THz) waveguide components. This technique provides precise dimensional control across multiple etch depths with batch processing capabilities. Nonlinear and passive components such as mixers and multipliers waveguides, hybrids, OMTs and twists have been fabricated and integrated into a small silicon package. This fabrication technique enables a wafer-stacking architecture to provide ultra-compact multi-pixel receiver front-ends in the THz range. |
FILED | Tuesday, April 15, 2014 |
APPL NO | 14/253541 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/16 (20130101) Original (OR) Class H01P 11/002 (20130101) H01P 11/006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461642 | Pickens et al. |
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FUNDED BY |
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APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
INVENTOR(S) | Keith S. Pickens (San Antonio, Texas); Robert E. Bolanos (San Antonio, Texas) |
ABSTRACT | A high-speed high-voltage pulser especially designed to operate in high radiation environments. The pulser uses a primary side driver and switches in front of an isolation gate transformer. The primary side driver and switches provide amplified and fast complementary pulse signals to the transformer. The transformer has top and bottom secondary windings, which respectively receive the complementary signals, and deliver them to secondary side drivers and switches. The switches are implemented with series-connected FETs. |
FILED | Wednesday, August 26, 2015 |
APPL NO | 14/835970 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Pulse Technique H03K 17/602 (20130101) H03K 17/6871 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 09456539 | Roth et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Gregory W. Roth (Furnace, Pennsylvania); Corey Dillon (Port Matilda, Pennsylvania); William Curran (Centre Hall, Pennsylvania); Christian Houser (Woodward, Pennsylvania) |
ABSTRACT | A no-till apparatus for application of herbicide and fertilizer, soil preparation, and seeding of a cover crop in a standing crop has inter-row assemblies configured to pass along inter-row areas between adjacent row lines of standing crop plants. Each assembly includes a fertilizer applicator, a no-till soil preparation element, a cover crop seed applicator, and a post-seeding element. The apparatus may include movable auxiliary seeding units such that the apparatus may operate as a grain drill. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/212473 |
ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Soil Working in Agriculture or Forestry; Parts, Details, or Accessories of Agricultural Machines or Implements, in General A01B 49/06 (20130101) Original (OR) Class Planting; Sowing; Fertilising A01C 5/062 (20130101) A01C 5/064 (20130101) A01C 7/006 (20130101) A01C 7/06 (20130101) A01C 23/047 (20130101) Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 7/0042 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 60/16 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09458422 | Lo et al. |
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FUNDED BY |
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APPLICANT(S) | Yangming Martin Lo (Ashton, Maryland); Irene N. N. Yossa (Silver Spring, Maryland); Neil A. Belson (Port Tobacco, Maryland) |
ASSIGNEE(S) | University of Maryland (College Park, Maryland); Leaf Pro, LLC (Wilson, North Carolina) |
INVENTOR(S) | Yangming Martin Lo (Ashton, Maryland); Irene N. N. Yossa (Silver Spring, Maryland); Neil A. Belson (Port Tobacco, Maryland) |
ABSTRACT | The invention describes a novel composition of matter obtained from the leaves of green plants, which is useful in promoting the growth of beneficial microorganisms. Specifically, that the invention describes a hydrolysate prepared from plant leaf biomass (leaf biomass hydrolysate or ‘LBH’) which dramatically stimulates the growth of beneficial microorganisms. Use of LBH as a fermentation substrate can also stimulate rapid production of organic acids and other organic compounds. LBH can be used as a substrate to promote the fermentation-based production of biobased industrial chemicals or biofuels, LBH can be utilized as a prebiotic to promote the growth of beneficial probiotic organisms, hi addition, LBH may also be useful in stimulating the fermentation-based production of other products, examples of which include preservatives, antibiotics, antigens, vaccines, amino acids, vitamins, recombinant proteins, bioremediation treatments, and immobilized enzymes. |
FILED | Monday, January 26, 2009 |
APPL NO | 12/864416 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/16 (20130101) Original (OR) Class C12N 1/20 (20130101) C12N 1/22 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/17 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 09459693 | Cohen et al. |
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FUNDED BY |
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APPLICANT(S) | SEARETE LLC, a limited liability corporation of the State of Delaware (Bellevue, Washington) |
ASSIGNEE(S) | Invention Science Fund I, LLC (Bellevue, Washington) |
INVENTOR(S) | Alexander J. Cohen (Mill Valley, California); Edward K. Y. Jung (Bellevue, Washington); Royce A. Levien (Lexington, Massachusetts); Robert W. Lord (Seattle, Washington); Mark A. Malamud (Seattle, Washington); John D. Rinaldo, Jr. (Bellevue, Washington) |
ABSTRACT | Embodiments include an article of manufacture, apparatus, device, system, computer-program product, and method. In an embodiment, system is provided that includes at least two machine-differentiatable identifiers, each identifier of the at least two machine-differentiatable identifiers being respectively keyed to a data recipient and associatable with a hand-formed mark on a surface. The system also includes a commonly accepted meaning respectively associated by a group of users with each machine-differentiatable identifier of the at least two machine-differentiatable identifiers. The system may include a surface displaying the at least two machine-differentiatable identifiers. The system may include a surface displaying the at least two machine-differentiatable identifiers and the commonly accepted meaning respectively associated by a group of users with each machine-differentiatable identifier of the at least two machine-differentiatable identifiers. |
FILED | Monday, February 10, 2014 |
APPL NO | 14/177101 |
ART UNIT | 2626 — Selective Visual Display Systems |
CURRENT CPC | Electric Digital Data Processing G06F 3/002 (20130101) G06F 3/013 (20130101) Original (OR) Class G06F 3/038 (20130101) G06F 3/03545 (20130101) G06F 3/04883 (20130101) G06F 17/241 (20130101) G06F 17/243 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/24 (20130101) G06K 9/222 (20130101) G06K 9/00402 (20130101) G06K 9/2063 (20130101) G06K 2209/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09461676 | Santucci et al. |
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FUNDED BY |
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APPLICANT(S) | Robert Santucci (Gilbert, Arizona); Mahesh K. Banavar (Tempe, Arizona); Andreas Spanias (Tempe, Arizona); Cihan Tepedelenlioglu (Chandler, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Robert Santucci (Gilbert, Arizona); Mahesh K. Banavar (Tempe, Arizona); Andreas Spanias (Tempe, Arizona); Cihan Tepedelenlioglu (Chandler, Arizona) |
ABSTRACT | Some embodiments include a distributed estimation system. Other embodiments of related systems and methods are also disclosed. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/213624 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Transmission H04B 1/0475 (20130101) Original (OR) Class H04B 1/0483 (20130101) H04B 2001/0425 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 09460921 | Bertness et al. |
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FUNDED BY |
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APPLICANT(S) | NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland); Matthew D. Brubaker (Louisville, Colorado); William M. Old (Denver, Colorado) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia); REGENTS OF THE UNIVERISTY OF COLORADO (Denver, Colorado) |
INVENTOR(S) | Kristine A. Bertness (Boulder, Colorado); Matthew D. Brubaker (Louisville, Colorado); William M. Old (Denver, Colorado) |
ABSTRACT | A nanowire article includes a substrate; a plurality of nanowires disposed on the substrate, the nanowires comprising a semiconductor nitride, the semiconductor comprising an element selected from group 3 of the periodic table; and a superlattice layer interposed between the substrate and the plurality of gallium nitride nanowires. A process for producing a nanowire article includes disposing a superlattice layer on a substrate; disposing a first buffer layer on the superlattice layer; contacting the first buffer layer with a precursor; and forming a plurality of nanowires from the precursor on the first buffer layer to form the nanowire article, the nanowires comprising a semiconductor nitride, the semiconductor comprising an element selected from group 3 of the periodic table. A process for producing a nanowire article includes nitrogenating a substrate to form a nitrogenated layer on the substrate; contacting the nitrogenated layer with a precursor; and forming a plurality of gallium nitride nanowires from the precursor on the nitrogenated layer to form the nanowire article in an absence of a catalyst, wherein individual gallium nitride nanowires of the plurality of gallium nitride nanowires include a length axis that is substantially perpendicular to the nitrogenated layer. |
FILED | Monday, April 06, 2015 |
APPL NO | 14/679249 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) B82Y 40/00 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/403 (20130101) C30B 29/406 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02381 (20130101) H01L 21/02433 (20130101) H01L 21/02439 (20130101) H01L 21/02458 (20130101) H01L 21/02507 (20130101) H01L 21/02603 (20130101) Original (OR) Class H01L 21/02642 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
US 09457004 | Garvey |
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FUNDED BY |
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APPLICANT(S) | Bikam Pharmaceuticals, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | BIKAM PHARMACEUTICALS INC. (Cambridge, Massachusetts) |
INVENTOR(S) | David S. Garvey (Dover, Massachusetts) |
ABSTRACT | Compounds are disclosed that are useful for treating ophthalmic conditions caused by or related to production of toxic visual cycle products that accumulate in the eye, such as dry adult macular degeneration, as well as conditions caused by or related to the misfolding of mutant opsin proteins and/or the mis-localization of opsin proteins. Compositions of these compounds alone or in combination with other therapeutic agents are also described, along with therapeutic methods of using such compounds and/or compositions. Methods of synthesizing such agents are also disclosed. |
FILED | Thursday, August 13, 2015 |
APPL NO | 14/825699 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/045 (20130101) A61K 31/277 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 25/06 (20130101) C07C 25/13 (20130101) C07C 25/18 (20130101) C07C 33/14 (20130101) C07C 33/34 (20130101) C07C 33/50 (20130101) C07C 43/23 (20130101) C07C 49/84 (20130101) C07C 49/792 (20130101) C07C 49/813 (20130101) C07C 255/53 (20130101) C07C 255/56 (20130101) C07C 259/18 (20130101) C07C 2101/14 (20130101) Heterocyclic Compounds C07D 307/42 (20130101) C07D 307/46 (20130101) C07D 333/16 (20130101) C07D 333/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
General Services Administration (GSA)
US 09459845 | Petro et al. |
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FUNDED BY |
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APPLICANT(S) | Piksel, Inc. (Wilmington, Delaware) |
ASSIGNEE(S) | Piksel, Inc. (Wilmington, Delaware) |
INVENTOR(S) | Michael Anthony Petro (Rockaway, New Jersey); Keith David Schnable (Redmond, Washington); David Persing (Issaquah, Washington); Maxim Gubin (Forest Hills, New York); Leonid Geller (Secaucus, New Jersey); Joseph Jacques-Andre Chamberland (Toronto, Canada); David Martin Anderson (Lynnwood, Washington) |
ABSTRACT | Methods and systems for a disabled user compliant video player for an end-to-end streaming web video solution affording accessibility for disabled users, including blind users and those with partial or poor vision, colorblind users, deaf users and those limited to only keyboard/voice input. Another embodiment of the present invention is directed to systems and methods for real-time creation and modification of specialized media players, to be used as stand-alone applications or as embedded data display applications. |
FILED | Tuesday, December 16, 2014 |
APPL NO | 14/572099 |
ART UNIT | 2199 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04842 (20130101) G06F 8/20 (20130101) G06F 8/34 (20130101) Original (OR) Class G06F 8/38 (20130101) G06F 8/41 (20130101) G06F 8/60 (20130101) G06F 8/65 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 65/4084 (20130101) Pictorial Communication, e.g Television H04N 21/4884 (20130101) H04N 21/8193 (20130101) H04N 21/8543 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 09457853 | Anderfaas et al. |
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FUNDED BY |
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APPLICANT(S) | MillenWorks (Tustin, California) |
ASSIGNEE(S) | MillenWorks (Tustin, California) |
INVENTOR(S) | Eric N. Anderfaas (Westminster, California); Matthew M. O'Brien (Hermosa Beach, California) |
ABSTRACT | The track tension of a tracked vehicle is actively controlled by a track tensioner system that is positioned behind or within an idler wheel of a tracked vehicle. The system employs no exposed hydraulic line and is operable to default to a passive tensioning mode in the event of a system failure. The hydraulic circuit of the track tensioner system is powered by the rotation of the idler wheel inside which the system resides. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/830638 |
ART UNIT | 3618 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Motor Vehicles; Trailers B62D 55/305 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Tennessee Valley Authority (TVA)
US 09459600 | Huffine |
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FUNDED BY |
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APPLICANT(S) | Tennessee Valley Authority (Knoxville, Tennessee) |
ASSIGNEE(S) | Tennessee Valley Authority (Knoxville, Tennessee) |
INVENTOR(S) | Brian Jason Huffine (Knoxville, Tennessee) |
ABSTRACT | A method and an automation system for processing information extractable from an engineering drawing file. The automation system includes a controller which models in the engineering drawing file (20) at least two objects (302, 304) in a predefined format by adding at least two entities (34) to the engineering drawing file (20) (S501) and by adding support information (35) to the engineering drawing file (20) (S502) to provide the extractable information (S401), provides a program sequence (80) in an automation application (50) to establish a correlation of the extractable information (S402), correlates the extractable information by executing the program sequence (80) (S403), and generates output data (12, 15) based on the established correlation of the extractable information (S404). The correlation of the extractable information is established only while the program sequence (80) of the automation application (50) is being executed. |
FILED | Friday, November 09, 2012 |
APPL NO | 13/824880 |
ART UNIT | 2126 — AI & Simulation/Modeling |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/04 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/5009 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 04, 2016.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
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THE PANEL
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FUNDED BY
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Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
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Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
The date of the patent application including the day of the week.
APPL NO
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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