FedInvent™ Patents

Patent Details for Tuesday, October 25, 2016 

This page was updated on Monday, March 27, 2023 at 04:53 AM GMT

Department of Health and Human Services (HHS) 

US 09474254 Hamra
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Board of Regents of The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Franklin Kent Hamra (Keller, Texas)
ABSTRACT A spermatogonial stem cell line that is derived from testes of rats characterized by a desirable genetic background can serve as a source for cells to transplant into male-sterile recipient animals that are immuno-compatible with the spermatogonial line. Rat cells thus transplanted readily develop into fertilization-competent, haploid male gametes, with little or no endogenous sperm competition generated by the testes of the male-sterile recipient. This approach, constituting the first vector system for the use of rat spermatogonial lines from in vitro culture in generating mutant rats on a desired genetic background, effects maximal germline transmission of donor haplotypes from the transplanted spermatogonial cells.
FILED Friday, May 23, 2014
APPL NO 14/286468
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/02 (20130101)
A01K 67/0271 (20130101) Original (OR) Class
A01K 67/0275 (20130101)
A01K 2217/07 (20130101)
A01K 2227/10 (20130101)
A01K 2227/105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/061 (20130101)
C12N 2500/44 (20130101)
C12N 2501/13 (20130101)
C12N 2501/115 (20130101)
C12N 2800/90 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474271 John et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute on Aging (NIA)
National Science Foundation (NSF)
APPLICANT(S) Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York);  The Curators of The University of Missouri (Columbia, Missouri);  University of North Texas (Denton, Texas)
INVENTOR(S) George John (New York, New York);  Subbiah Nagarajan (New York, New York);  Kent Chapman (Denton, Texas);  Lionel Faure (Flower Mound, Texas);  Peter Koulen (Leawood, Kansas)
ABSTRACT A method for enhancing amidohydrolase activity of Fatty Acid Amide Hydrolase (FAAH) is disclosed. The method comprising administering a phenoxyacylethanolamide that causes the enhanced activity. The enhanced activity can have numerous effects on biological organisms including, for example, enhancing the growth of certain seedlings. The subject matter disclosed herein relates to enhancers of amidohydrolase activity.
FILED Friday, January 17, 2014
APPL NO 14/761826
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 37/20 (20130101) Original (OR) Class
A01N 39/04 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474461 Fisher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) John H. Fisher (Cottonwood Heights City, Utah);  F. Edward Dudek (Salt Lake City, Utah);  Mark J. Lehmkuhle (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) John H. Fisher (Cottonwood Heights City, Utah);  F. Edward Dudek (Salt Lake City, Utah);  Mark J. Lehmkuhle (Salt Lake City, Utah)
ABSTRACT Provided herein are embodiments of a miniature wireless biomedical telemetry device along with systems and methods for its use. A miniature amplifier and transmitter allow recording of physiological signals from small animals, such as rats, mice and birds, as well as humans. The device is positioned externally and is easily replaceable, as is its battery, so surgical complications and other problem problems are minimized.
FILED Thursday, October 02, 2008
APPL NO 12/681408
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0006 (20130101)
A61B 5/0402 (20130101)
A61B 5/0476 (20130101) Original (OR) Class
A61B 5/4094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474630 Veatch
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Invisible Hand Enterprises, LLC (Westminster, Colorado)
ASSIGNEE(S) Invisible Hand Enterprises, LLC (Westminster, Colorado)
INVENTOR(S) Bradley Delton Veatch (Westminster, Colorado)
ABSTRACT This disclosure relates to the field of prosthetics, more specifically to a pinless anthropomorphic hinge or joint, and a digit comprising one or more phalanges connected by and articulating around pinless joints, whereby the joints provide compliant movement in more than one plane. This disclosure also relates to modular prosthetic systems comprising multiple digits, in particular for partial-hand replacements.
FILED Wednesday, March 12, 2014
APPL NO 14/205997
ART UNIT 3738 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/68 (20130101)
A61F 2/583 (20130101)
A61F 2/586 (20130101) Original (OR) Class
A61F 2002/5093 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474717 von Andrian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (, None);  The Children's Medical Center Corporation (, None);  President and Fellows of Harvard College (, None);  The Brigham and Women's Hospital, Inc. (, None)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Children's Medical Center Corporation (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Ulrich H. von Andrian (Chestnut Hill, Massachusetts);  Omid C. Farokhzad (Waban, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Tobias Junt (Schorndorf, Germany);  Elliott Ashley Moseman (Jamaica Plain, Massachusetts);  Liangfang Zhang (San Diego, California);  Pamela Basto (Cambridge, Massachusetts);  Matteo Iannacone (Milan, Italy);  Frank Alexis (Greenville, South Carolina)
ABSTRACT The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at last one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof.
FILED Friday, March 15, 2013
APPL NO 13/844100
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101) Original (OR) Class
A61K 39/00 (20130101)
A61K 39/0011 (20130101)
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 47/48815 (20130101)
A61K 47/48915 (20130101)
A61K 2039/60 (20130101)
A61K 2039/555 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474745 Spiekerkoetter et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Edda Spiekerkoetter (Stanford, California);  Marlene Rabinovitch (Stanford, California);  Philip A. Beachy (Stanford, California);  David Solow-Cordero (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Edda Spiekerkoetter (Stanford, California);  Marlene Rabinovitch (Stanford, California);  Philip A. Beachy (Stanford, California);  David Solow-Cordero (Stanford, California)
ABSTRACT A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.
FILED Monday, April 30, 2012
APPL NO 14/113375
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/436 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474749 Stefano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Research Foundation for the State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) George B. Stefano (Melville, New York);  Patrick Cadet (Elmont, New York);  Kirk J. Mantione (Patchogue, New York);  Wei Zhu (West Babylon, New York)
ABSTRACT Methods and materials related to the use of morphine, morphine precursors (e.g., reticuline), and inhibitors of morphine synthesis or activity to treat diseases, to reduce inflammation, or to restore normal function are provided.
FILED Friday, August 15, 2014
APPL NO 14/460809
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 1/30 (20130101)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)
A23V 2002/00 (20130101)
A23V 2200/322 (20130101)
A23V 2250/30 (20130101)
A23V 2250/0606 (20130101)
A23V 2250/1626 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/194 (20130101)
A61K 31/198 (20130101)
A61K 31/198 (20130101)
A61K 31/472 (20130101)
A61K 31/485 (20130101) Original (OR) Class
A61K 31/485 (20130101)
A61K 31/7052 (20130101)
A61K 31/7052 (20130101)
A61K 33/04 (20130101)
A61K 33/04 (20130101)
A61K 33/06 (20130101)
A61K 33/06 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474753 Moussa
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Georgetown University (Washington, District of Columbia)
ASSIGNEE(S) GEORGETOWN UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) Charbel Moussa (Germantown, Maryland)
ABSTRACT Provided herein are methods of treating or preventing a neurodegenerative disease, a myodegenerative disease or a prion disease in a subject comprising administering a tyrosine kinase inhibitor.
FILED Thursday, May 02, 2013
APPL NO 14/398379
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/506 (20130101) Original (OR) Class
A61K 31/506 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474759 Chang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Kansas State University Research Foundation (Manhattan, Kansas);  The Ohio State University (Columbus, Ohio);  Wichita State University (Wichita, Kansas)
ASSIGNEE(S) Kansas State University Research Foundation (Manhattan, Kansas);  The Ohio State University (Columbus, Ohio);  Wichita State University (Wichita, Kansas)
INVENTOR(S) Kyeong-Ok Chang (Manhattan, Kansas);  Yunjeong Kim (Manhattan, Kansas);  William C. Groutas (Wichita, Kansas);  Duy Hua (Manhattan, Kansas);  Linda J. Saif (Wooster, Ohio)
ABSTRACT Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl α-ketoamides, peptidyl bisulfate salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis A virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus.
FILED Thursday, September 27, 2012
APPL NO 14/347756
ART UNIT 1675 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/422 (20130101)
A61K 31/427 (20130101)
A61K 31/4015 (20130101)
A61K 31/5377 (20130101) Original (OR) Class
A61K 38/06 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 207/27 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2770/16011 (20130101)
C12N 2770/20011 (20130101)
C12N 2770/32111 (20130101)
C12N 2770/32311 (20130101)
C12N 2770/32411 (20130101)
C12N 2770/32611 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474761 Weglicki et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) William B. Weglicki (Potomac, Maryland);  Iu Tong Mak (Gaithersburg, Maryland)
ASSIGNEE(S) THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) William B. Weglicki (Potomac, Maryland);  Iu Tong Mak (Gaithersburg, Maryland)
ABSTRACT The present disclosure provides methods for alleviating or preventing the negative physiological side effects associated with the administration of EGFR blocking therapeutics. The disclosure provides, inter alia, methods for treating or preventing: hypomagnesemia, cardiac dysfunction, and skin lesions, which are induced by EGFR blocking drugs, by administering an NK-1 receptor antagonist.
FILED Wednesday, June 10, 2015
APPL NO 14/735396
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/444 (20130101)
A61K 31/495 (20130101)
A61K 31/4035 (20130101)
A61K 31/4985 (20130101)
A61K 31/5377 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474785 Mohammadi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Moosa Mohammadi (Scarsdale, New York);  Regina Goetz (New York, New York)
ABSTRACT The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and the C-terminus includes a C-terminal portion of an FGF19 molecule. The portion of the paracrine FGF is modified to decrease binding affinity for heparin and/or heparan sulfate compared to the portion without the modification. The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention.
FILED Friday, March 15, 2013
APPL NO 13/838350
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1825 (20130101) Original (OR) Class
A61K 38/1825 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 14/50 (20130101)
C07K 14/503 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474788 Verdin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Eric M. Verdin (San Francisco, California);  Steven E. Kauder (San Francisco, California)
ASSIGNEE(S) The J. David Gladstone Institutes (San Francisco, California)
INVENTOR(S) Eric M. Verdin (San Francisco, California);  Steven E. Kauder (San Francisco, California)
ABSTRACT The present disclosure provides methods and compositions for reactivating latent immunodeficiency virus in an immunodeficiency virus-infected cell. The methods generally involve contacting an immunodeficiency virus-infected cell with a synergistically effective amount of an inhibitor of cytosine methylation and an NF-κB activator. The present disclosure provides methods and compositions for reducing the reservoir of latent immunodeficiency virus in an individual, and for treating an immunodeficiency virus infection in an individual.
FILED Friday, April 15, 2011
APPL NO 13/088136
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/15 (20130101)
A61K 31/15 (20130101)
A61K 31/166 (20130101)
A61K 31/166 (20130101)
A61K 31/353 (20130101)
A61K 31/353 (20130101)
A61K 31/405 (20130101)
A61K 31/405 (20130101)
A61K 31/495 (20130101)
A61K 31/495 (20130101)
A61K 31/513 (20130101)
A61K 31/513 (20130101)
A61K 31/7068 (20130101)
A61K 31/7068 (20130101)
A61K 38/191 (20130101) Original (OR) Class
A61K 38/191 (20130101)
A61K 38/1709 (20130101)
A61K 38/1709 (20130101)
A61K 38/2006 (20130101)
A61K 38/2006 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474793 Catanzaro et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Andrew Catanzaro (Washington, District of Columbia);  Robert Yarchoan (Bethesda, Maryland);  Jay A. Berzofsky (Bethesda, Maryland);  Takahiro Okazaki (Yokohama, Japan);  James T. Snyder, II (Phoenix, Arizona);  Samuel Broder (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Andrew Catanzaro (Washington, District of Columbia);  Robert Yarchoan (Bethesda, Maryland);  Jay A. Berzofsky (Bethesda, Maryland);  Takahiro Okazaki (Yokohama, Japan);  James T. Snyder, II (Phoenix, Arizona);  Samuel Broder (Bethesda, Maryland)
ABSTRACT The present invention provides methods for lowering a viral load of a virus resistant to an antiviral drug by inducing cytotoxic T lymphocytes (CTL) to recognize a predetermined mutated epitope within a viral protein of the drug-resistant virus. CTLs are induced by immunizing a host with a peptide comprising the predetermined mutation. The immunostimulating peptide may be further improved by epitope-enhancement for inducing specific CTLs. The antiviral protection against drug-resistant virus shown by compositions of the present invention and mediated by human HLA-restricted CTL has not been previously achieved.
FILED Wednesday, February 22, 2006
APPL NO 11/816704
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474795 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Che-Hung Robert Lee (Silver Spring, Maryland);  Carl E. Frasch (Martinsburg, West Virginia)
ABSTRACT Methods for synthesis and manufacture of polysaccharide-protein conjugate vaccines at high yield are provided. The methods involve reaction of a hydrazide group on one reactant with an aldehyde or cyanate ester group on the other reactant. The reaction proceeds rapidly with a high conjugation efficiency, such that a simplified purification process can be employed to separate the conjugate product from the unconjugated protein and polysaccharide and other small molecule by-products.
FILED Monday, November 02, 2015
APPL NO 14/930425
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/08 (20130101) Original (OR) Class
A61K 39/092 (20130101)
A61K 39/095 (20130101)
A61K 39/102 (20130101)
A61K 39/0275 (20130101)
A61K 47/4823 (20130101)
A61K 47/4833 (20130101)
A61K 47/48261 (20130101)
A61K 2039/627 (20130101)
A61K 2039/6037 (20130101)
A61K 2039/6087 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474796 Bergeron et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Colorado Seminary, which owns and Operates The University of Denver (Denver, Colorado)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia);  Colorado Seminary, which owns and operates the University of Denver (Denver, Colorado)
INVENTOR(S) Eric Bergeron (Atlanta, Georgia);  Scott Dusan Pegan (Denver, Colorado);  Stuart T. Nichol (Atlanta, Georgia);  Michelle Kay Deaton (Denver, Colorado)
ABSTRACT The genetically modified hemorrhagic fever virus of this invention possesses a viral ovarian tumor protease with decreased ability to remove ubiquitin (Ub) and ISG15 tags that the human organism uses to label proteins for removal. Unlike complete knockout strains, the modified virus retains enough activity for replication in a human cell line. This creates an immunogenic and non-pathogenic virus that can be used as an effective live vaccine agent.
FILED Thursday, March 14, 2013
APPL NO 13/829105
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/5254 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2760/12034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474798 Watanabe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Tokiko Watanabe (Madison, Wisconsin);  Yoshihiro Kawaoka (Middleton, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Tokiko Watanabe (Madison, Wisconsin);  Yoshihiro Kawaoka (Middleton, Wisconsin)
ABSTRACT A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus.
FILED Wednesday, June 18, 2008
APPL NO 12/214414
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/543 (20130101)
A61K 2039/5254 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 16/1018 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/00 (20130101)
C12N 2760/16011 (20130101)
C12N 2760/16021 (20130101)
C12N 2760/16022 (20130101)
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474806 Pier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Gerald B. Pier (Brookline, Massachusetts);  Nikolay Nifantiev (Moscow, Russian Federation);  Yury Tsvetkov (Moscow, Russian Federation);  Marina Gening (Moscow, Russian Federation)
ABSTRACT The invention relates to the compositions of synthetic oligo-β-(1→6)-2-amino-2-deoxy-D-glucopyranosides conjugated to carriers, and methods for making and use same.
FILED Friday, June 21, 2013
APPL NO 13/924435
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/085 (20130101)
A61K 47/4833 (20130101) Original (OR) Class
A61K 47/48261 (20130101)
A61K 2039/6037 (20130101)

Acyclic or Carbocyclic Compounds
C07C 327/32 (20130101)

Heterocyclic Compounds
C07D 207/46 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 3/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474809 Santra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
APPLICANT(S) Swadeshmukul Santra (Orlando, Florida);  James Turkson (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Swadeshmukul Santra (Orlando, Florida);  James Turkson (Orlando, Florida)
ABSTRACT An activatable nanoprobe is provided having a core component and an active agent associated with the core component via a bond configured to be cleaved upon exposure to an endogenous compound.
FILED Tuesday, June 24, 2014
APPL NO 14/313372
ART UNIT 1671 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0067 (20130101)
A61K 49/1833 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474909 Jung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Byunghoo Jung (West Lafayette, Indiana);  Babak Ziaie (West Lafayette, Indiana);  Wing Fai Loke (San Jose, California)
ABSTRACT Illustrative embodiments of systems and methods for wireless magnetic tracking are disclosed. In one illustrative embodiment, a wireless magnetic tracking system may include a plurality of transmitting coils each configured to generate a magnetic field when energized, an active transponder configured to simultaneously (i) obtain measurements of the magnetic field when one of the plurality of transmitting coils is energized and (ii) transmit a wireless signal containing data concerning the measurements, and a computing device configured to (i) cause each of the plurality of transmitting coils to be sequentially energized, (ii) receive the data concerning the measurements, and (iii) determine a position and an orientation of the active transponder relative to the plurality of transmitting coils in response to the data concerning the measurements.
FILED Wednesday, December 12, 2012
APPL NO 13/712532
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 2090/3958 (20160201)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/00 (20130101) Original (OR) Class
A61N 5/1049 (20130101)
A61N 2005/1051 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475756 Hartwig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) John Hartwig (Berkeley, California);  Patrick Fier (Berkeley, California)
ABSTRACT Selectively fluorinated molecules are important as materials, pharmaceuticals, and agrochemicals, but their synthesis by simple, mild, laboratory methods is challenging. We report a straightforward method for the cross-coupling of a difluoromethyl group with readily available reagents to form difluoromethylarenes. The reaction of electron-neutral, electron rich, and sterically hindered aryl and vinyl iodides with the combination of CuI, CsF and TMSCF2H leads to the formation of difluoromethylarenes in high yield with good functional group compatibility. This transformation is surprising, in part, because of the prior observation of the instability of CuCF2H.
FILED Tuesday, March 05, 2013
APPL NO 14/382991
ART UNIT 1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 39/00 (20130101)
C07B 2200/09 (20130101)

Acyclic or Carbocyclic Compounds
C07C 17/32 (20130101)
C07C 17/32 (20130101)
C07C 17/263 (20130101)
C07C 17/263 (20130101)
C07C 17/263 (20130101)
C07C 22/00 (20130101)
C07C 22/08 (20130101)
C07C 22/08 (20130101)
C07C 41/30 (20130101)
C07C 41/30 (20130101)
C07C 41/48 (20130101)
C07C 41/48 (20130101)
C07C 41/56 (20130101)
C07C 43/225 (20130101)
C07C 43/313 (20130101)
C07C 67/293 (20130101)
C07C 67/293 (20130101)
C07C 69/63 (20130101)
C07C 209/68 (20130101)
C07C 209/68 (20130101)
C07C 211/29 (20130101)
C07C 231/12 (20130101) Original (OR) Class
C07C 231/12 (20130101)
C07C 233/15 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475791 Thatcher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Gregory R. Thatcher (Chicago, Illinois);  Debra Tonetti (Westchester, Illinois);  Mary Ellen Molloy (Chicago, Illinois);  Bradley Michalsen (Grayslake, Illinois);  Zihui Qin (Mundelein, Illinois)
ABSTRACT Disclosed herein are methods for treatment of estrogen-related medical disorders. The methods of treatment may comprise administering to a subject in need of such treatment a composition comprising a therapeutically effective amount of at least one compound of formula (I) or a pharmaceutically acceptable salt thereof.
FILED Thursday, October 24, 2013
APPL NO 14/438326
ART UNIT 1671 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/381 (20130101)

Heterocyclic Compounds
C07D 333/64 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57496 (20130101)
G01N 2333/91205 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475832 Hostetler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California, a California corporation (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Karl Y. Hostetler (Del Mar, California);  James R. Beadle (San Diego, California);  Nadejda Valiaeva (San Diego, California)
ABSTRACT There are provided, inter alia, acyclic nucleoside phosphonate compounds having reduced toxicity and enhanced antiviral activity, and pharmaceutically accepted salts and solvates thereof. There are also provided methods of using the disclosed compounds for inhibiting viral RNA-dependent RNA polymerase, inhibiting viral reverse transcriptase, inhibiting replication of virus, including hepatitis C virus or a human retrovirus, and treating a subject infected with a virus, including hepatitis C virus or a human retrovirus.
FILED Monday, September 29, 2014
APPL NO 14/499865
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/52 (20130101)
A61K 31/522 (20130101)
A61K 31/675 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/65121 (20130101)
C07F 9/65616 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475834 Brady et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Sean Brady (New York, New York);  Hahk-Soo Kang (New York, New York)
ABSTRACT Anthracyclin compounds of the general structure:
are disclosed. In these compounds R1 is methyl, acetyl or hydroxyacetyl; R2—R5 and R10—R13 are independently H or methyl; R6 R7 and R8 are independently H, OH or OCH3; and n is zero or one. The compounds are useful for treating cancer.
FILED Friday, November 13, 2015
APPL NO 14/941029
ART UNIT 1673 — Organic Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/252 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475839 Tarasova et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Nadya I. Tarasova (Frederick, Maryland);  Giorgio Trinchieri (Potomac, Maryland);  Howard A. Young (North Potomac, Maryland);  C. Andrew Stewart (Frederick, Maryland);  Marco A. Cardone (Frederick, Maryland);  Alan O. Perantoni (Fairfield, Pennsylvania)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
INVENTOR(S) Nadya I. Tarasova (Frederick, Maryland);  Giorgio Trinchieri (Potomac, Maryland);  Howard A. Young (North Potomac, Maryland);  C. Andrew Stewart (Frederick, Maryland);  Marco A. Cardone (Frederick, Maryland);  Alan O. Perantoni (Fairfield, Pennsylvania)
ABSTRACT A peptide or peptidomimetic comprising an amino acid sequence based on conserved regions of IL10 or IFN-gamma receptor sequences, and related compounds and compositions, as well as methods for the use thereof to inhibit cytokine signaling.
FILED Wednesday, May 11, 2011
APPL NO 13/697259
ART UNIT 1676 — Organic Chemistry
CURRENT CPC
Peptides
C07K 7/06 (20130101)
C07K 7/08 (20130101) Original (OR) Class
C07K 14/001 (20130101)
C07K 14/4703 (20130101)
C07K 14/7155 (20130101)
C07K 14/7156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475845 Asokan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Aravind Asokan (Chapel Hill, North Carolina);  Richard Jude Samulski (Chapel Hill, North Carolina)
ABSTRACT The present invention provides AAV capsid proteins (VP1, VP2 and/or VP3) comprising a modification in the amino acid sequence in the three-fold axis loop 4 and virus capsids and virus vectors comprising the modified AAV capsid protein. In particular embodiments, the modification comprises a substitution of one or more amino acids at amino acid positions 585 to 590 (inclusive) of the native AAV2 capsid protein sequence or the corresponding positions of other AAV capsid proteins. The invention also provides methods of administering the virus vectors and virus capsids of the invention to a cell or to a subject in vivo.
FILED Monday, November 17, 2014
APPL NO 14/543459
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2810/6027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475850 Chugh
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Sumant S. Chugh (Mountain Brook, Alabama)
ASSIGNEE(S) THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
INVENTOR(S) Sumant S. Chugh (Mountain Brook, Alabama)
ABSTRACT The present disclosure provides a method for treating and/or preventing a condition characterized as a nephrotic syndrome, such as but not limited to minimal change disease (MCD) and membranous nephropathy (MN), and conditions related to nephrotic syndrome, such as but not limited to, proteinuria and edema, as well as diabetic nephropathy, diabetes mellitus, lupus nephritis or primary glomerular disease. The present disclosure further provides methods for reducing proteinuria and other disease states as discussed herein. Such methods comprise the therapeutic delivery of an Angptl4 polypeptide or Angptl4 polypeptide derivative to a subject.
FILED Thursday, February 02, 2012
APPL NO 13/364962
ART UNIT 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/22 (20130101)
A61K 38/1709 (20130101)

Peptides
C07K 14/72 (20130101)
C07K 14/435 (20130101) Original (OR) Class
C07K 14/515 (20130101)
C07K 14/575 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475853 Hazlett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) ALBANY MEDICAL COLLEGE (Albany, New York)
ASSIGNEE(S) ALBANY MEDICAL COLLEGE (Albany, New York)
INVENTOR(S) Karsten Hazlett (East Berne, New York);  Edmund Gosselin (Glenmont, New York);  Timothy Sellati (Saranac Lake, New York);  Tiffany Zarrella (Albany, New York)
ABSTRACT Establishment of an effective and uniform vaccine development strategy is key to conquering current and emerging infectious diseases. Despite successes against an array of bacterial agents, current approaches to vaccine development are as diverse as the microbes they target and require adjuvants that often have limited efficacy and/or toxic side effects. As a consequence, vaccine discovery is often slow, inefficient, and unsuccessful in the case of many high priority pathogens. The present disclosure suggests that vaccine generation for bacterial pathogens can be improved by optimizing the efficiency of processing/presentation of a bacterial immunogen via the targeting of immunogen to CR2 and/or TLR2 on APCs. This approach not only yields an adjuvant-free mucosal vaccine against a Category A biothreat agent, but also establishes a novel genetic approach/platform for vaccine development, which is applicable to many other infectious agents, thereby profoundly impacting preventive medicine/public health.
FILED Tuesday, January 22, 2013
APPL NO 14/373212
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0208 (20130101)
A61K 39/0291 (20130101)
A61K 2039/53 (20130101)
A61K 2039/6031 (20130101)

Peptides
C07K 14/195 (20130101)
C07K 14/472 (20130101) Original (OR) Class
C07K 2319/00 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475855 Kitajewski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Jan Kitajewski (Ridgewood, New Jersey);  Carrie Shawber (Washington Township, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Jan Kitajewski (Ridgewood, New Jersey);  Carrie Shawber (Washington Township, New Jersey)
ABSTRACT This invention provides a fusion protein comprising a signal peptide, EGF repeats 1-X of the extracellular domain of human Notch3 receptor protein wherein X is any integer from 12 to 34, and an Fc portion of an antibody bound thereto. This invention also provides a method for treating a subject having a tumor, a method for inhibiting angiogenesis in a subject, a method for treating a subject having ovarian cancer, and a method for treating a subject having a metabolic disorder, comprising administering to the subject an amount of the above fusion protein effective to treat the subject. This invention further provides uses of the above fusion protein for the preparation of a pharmaceutical composition for the treatment of a subject having a tumor, for inhibiting angiogenesis in a subject, for treating a subject having ovarian cancer, and for treating a subject having a metabolic disorder.
FILED Friday, August 21, 2009
APPL NO 13/060254
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/177 (20130101)
A61K 38/179 (20130101)
A61K 38/1793 (20130101)
A61K 39/395 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/71 (20130101)
C07K 14/485 (20130101) Original (OR) Class
C07K 14/705 (20130101)
C07K 14/715 (20130101)
C07K 16/46 (20130101)
C07K 2319/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475856 Mohammadi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Moosa Mohammadi (Scarsdale, New York);  Regina Goetz (New York, New York)
ABSTRACT The present invention relates to chimeric proteins that include an N-terminus coupled to a C-terminus, where the N-terminus includes an N-terminal portion of fibroblast growth factor 21 (“FGF21”) and the C-terminus includes a C-terminal portion of fibroblast growth factor 19 (“FGF19”). The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, as well as methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, methods of treating a subject in need of increased FGF21-βKlotho-FGF receptor complex formation, methods of causing increased FGF21 receptor agonist-βKlotho-FGF receptor complex formation, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention.
FILED Monday, March 04, 2013
APPL NO 13/784289
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/1825 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/50 (20130101) Original (OR) Class
C07K 2319/00 (20130101)
C07K 2319/21 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 2333/50 (20130101)
G01N 2500/02 (20130101)
G01N 2800/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475862 Connors et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Mark Connors (Bethesda, Maryland);  Jinghe Huang (Bethesda, Maryland);  Leo B. Laub (Richmond, Virginia);  Peter Kwong (Washington, District of Columbia);  Gary Nabel (Cambridge, Massachusetts);  John R. Mascola (Rockville, Maryland);  Baoshan Zhang (Bethesda, Maryland);  Rebecca S. Rudicell (Silver Springs, Maryland);  Ivelin Georgiev (Gaithersburg, Maryland);  Yongping Yang (Potomac, Maryland);  Jiang Zhu (Ashburn, Virginia);  Gilad Ofek (Washington, District of Columbia)
ABSTRACT Monoclonal neutralizing antibodies are disclosed that specifically bind to the HIV-1 gp41 membrane-proximal external region (MPER). Also disclosed are compositions including the disclosed antibodies that specifically bind gp41, nucleic acids encoding these antibodies, expression vectors including the nucleic acids, and isolated host cells that express the nucleic acids. The antibodies and compositions disclosed herein can be used for detecting the presence of HIV-1 in a biological sample, or detecting an HIV-1 infection or diagnosing AIDS in a subject. In additional, the broad neutralization breadth of the disclosed antibodies makes them ideal for treating a subject with an HIV infection. Thus, disclosed are methods of treating and/or preventing HIV infection.
FILED Wednesday, November 07, 2012
APPL NO 14/356557
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 45/06 (20130101)
A61K 49/0004 (20130101)

Peptides
C07K 16/00 (20130101)
C07K 16/1045 (20130101) Original (OR) Class
C07K 16/1063 (20130101)
C07K 2317/14 (20130101)
C07K 2317/34 (20130101)
C07K 2317/55 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56972 (20130101)
G01N 33/56983 (20130101)
G01N 2333/161 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475864 Ram et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sanjay Ram (Worcester, Massachusetts);  Tathagat Duttaray (Worcester, Massachusetts);  Peter A. Rice (Southborough, Massachusetts);  Lisa A. Lewis (Hudson, Massachusetts);  Sunita Gulati (Spencer, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Sanjay Ram (Worcester, Massachusetts);  Tathagat Duttaray (Worcester, Massachusetts);  Peter A. Rice (Southborough, Massachusetts);  Lisa A. Lewis (Hudson, Massachusetts);  Sunita Gulati (Spencer, Massachusetts)
ABSTRACT The invention provides compositions and methods for screening subjects at risk for contracting meningococcal disease and/or at risk for failing to elicit an immunogenic response to a vaccine against Neisseria meningitidis. The invention also provides kits for carrying out these screens, and improved vaccines against Neisseria meningitidis.
FILED Friday, September 04, 2009
APPL NO 13/062181
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/095 (20130101)
A61K 2039/505 (20130101)
A61K 2039/522 (20130101)

Peptides
C07K 14/22 (20130101)
C07K 16/1217 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/569 (20130101)
G01N 2333/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475874 Sawada et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MabVax Therapeutics, Inc. (San Diego, California)
ASSIGNEE(S) MABVAX THERAPEUTICS, INC. (San Diego, California)
INVENTOR(S) Ritsuko Sawada (San Diego, California);  Shu-Man Sun (San Diego, California);  Wolfgang Scholz (San Diego, California)
ABSTRACT The present invention provides compositions for the production of an antibody or functional fragment thereof directed against Sialyl-Lewisa (sLea). The compositions of the invention include polynucleotides encoding a heavy chain and/or a light chain variable domain that binds to sLea. The invention also provides an isolated antibody or functional fragment thereof and methods of treating or preventing a disease, such as cancer or tumor formation, wherein the antibody or functional fragment includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. The invention further provides a conjugate of an antibody or functional fragment thereof conjugated or recombinantly fused to a diagnostic agent, detectable agent or therapeutic agent, and methods of treating, preventing or diagnosing a disease in a subject in need thereof.
FILED Tuesday, August 26, 2014
APPL NO 14/468827
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)
A61K 39/39533 (20130101)
A61K 45/06 (20130101)
A61K 51/1045 (20130101)
A61K 51/1057 (20130101)
A61K 2039/505 (20130101)
A61K 2039/6081 (20130101)

Peptides
C07K 16/28 (20130101) Original (OR) Class
C07K 16/3076 (20130101)
C07K 2317/21 (20130101)
C07K 2317/33 (20130101)
C07K 2317/56 (20130101)
C07K 2317/77 (20130101)
C07K 2317/92 (20130101)
C07K 2317/732 (20130101)
C07K 2317/734 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475882 Clemmons et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) David R. Clemmons (Chapel Hill, North Carolina);  Laura A. Maile (Chapel Hill, North Carolina)
ABSTRACT Provided herein is technology relating to antagonists that inhibit, reduce, or minimize the interaction of integrin associated protein (IAP) with Src homology 2 (SH2) domain-containing protein tyrosine phosphatase substrate 1 (SHPS1) and particularly, but not exclusively, to compositions comprising such antagonists and methods of treatment comprising administering such antagonists.
FILED Friday, November 08, 2013
APPL NO 14/076130
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/2803 (20130101)
C07K 16/2896 (20130101) Original (OR) Class
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476029 Chang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Lung-Ji Chang (Gainesville, Florida)
ASSIGNEE(S)
INVENTOR(S) Lung-Ji Chang (Gainesville, Florida)
ABSTRACT Disclosed herein are new methods of producing a novel line of dendritic cells. The method comprises subjecting a sample of hematopoietic stem/precursor cells to a first feeder culture system that is supplemented with a first set of factors and a second feeder culture system supplemented with a second group of factors. The disclosure also pertains to new cell types that may be used as cancer immunotherapy.
FILED Monday, November 14, 2011
APPL NO 13/885025
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/15 (20130101)
A61K 39/0011 (20130101)
A61K 2039/5154 (20130101)
A61K 2039/5156 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0639 (20130101) Original (OR) Class
C12N 2501/22 (20130101)
C12N 2501/25 (20130101)
C12N 2501/26 (20130101)
C12N 2501/052 (20130101)
C12N 2501/125 (20130101)
C12N 2501/145 (20130101)
C12N 2501/2302 (20130101)
C12N 2501/2304 (20130101)
C12N 2501/2307 (20130101)
C12N 2501/2315 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476032 Wimmer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
APPLICANT(S) Eckard Wimmer (East Setauket, New York);  Steve Skiena (Setauket, New York);  Steffen Mueller (Kings Point, New York);  Bruce Futcher (Stony Brook, New York);  Dimitris Papamichail (South Miami, Florida);  John Robert Coleman (Blauvelt, New York);  Jeronimo Cello (Port Jefferson, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Eckard Wimmer (East Setauket, New York);  Steve Skiena (Setauket, New York);  Steffen Mueller (Kings Point, New York);  Bruce Futcher (Stony Brook, New York);  Dimitris Papamichail (South Miami, Florida);  John Robert Coleman (Blauvelt, New York);  Jeronimo Cello (Port Jefferson, New York)
ABSTRACT This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus.
FILED Monday, March 31, 2008
APPL NO 12/594173
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/5254 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2720/12361 (20130101)
C12N 2740/15061 (20130101)
C12N 2760/16061 (20130101)
C12N 2770/20061 (20130101)
C12N 2770/24161 (20130101)
C12N 2770/32061 (20130101)
C12N 2770/32661 (20130101)
C12N 2770/32761 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476042 Singh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Ravindra N. Singh (Shrewsbury, Massachusetts);  Natalia N. Singh (Shrewsbury, Massachusetts);  Nirmal K. Singh (Temple, Texas);  Elliot J. Androphy (Natick, Massachusetts)
ABSTRACT The present invention is directed to methods and compositions capable of blocking the inhibitory effect of a newly-identified intronic inhibitory sequence element, named ISS-N1 (for “intronic splicing silencer”), located in the SMN2 gene. The compositions and methods of the instant invention include oligonucleotide reagents (e.g., oligoribonucleotides) that effectively target the SMN2 ISS-N1 site in the SMN2 pre-mRNA, thereby modulating the splicing of SMN2 pre-mRNA to include exon 7 in the processed transcript. The ISS-N1 blocking agents of the invention cause elevated expression of SMN protein, thus compensating for the loss of SMN protein expression commonly observed in subjects with spinal muscular atrophy (SMA).
FILED Tuesday, October 15, 2013
APPL NO 14/054055
ART UNIT 1674 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2320/33 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6896 (20130101)
G01N 2500/04 (20130101)
G01N 2800/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476046 Naar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Anders M. Naar (Arlington, Massachusetts);  Seyed Hani Najafi-Shoushtari (Brighton, Massachusetts)
ABSTRACT Methods for targeting microRNA 128 (miR-128) for regulating cholesterol/lipid metabolism and insulin sensitivity.
FILED Thursday, April 30, 2015
APPL NO 14/701150
ART UNIT 1674 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/113 (20130101)
C12N 2310/315 (20130101)
C12N 2310/3231 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476048 Pfeffer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Sebastien Pfeffer (New York, New York);  Thomas Tuschl (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Sebastien Pfeffer (New York, New York);  Thomas Tuschl (New York, New York)
ABSTRACT The invention relates to isolated nucleic acid molecules comprising the sequence of a human cytomegalovirus microRNA. In another embodiment, the invention relates to single stranded DNA virus microRNA molecules comprising the sequence of a human cytomegalovirus microRNA. The invention also relates to the anti-DNA virus microRNA molecules.
FILED Wednesday, November 30, 2011
APPL NO 13/307694
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/1131 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/53 (20130101)
C12N 2310/111 (20130101)
C12N 2320/11 (20130101)
C12N 2330/10 (20130101)
C12N 2330/31 (20130101)
C12N 2710/16022 (20130101)
C12N 2710/16222 (20130101)
C12N 2710/16422 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476054 Drmanac et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Radoje T. Drmanac (Los Altos Hills, California);  Matthew Callow (Redwood City, California);  Snezana Drmanac (Los Altos Hills, California)
ASSIGNEE(S) Complete Genomics, Inc. (Mountain View, California)
INVENTOR(S) Radoje T. Drmanac (Los Altos Hills, California);  Matthew Callow (Redwood City, California);  Snezana Drmanac (Los Altos Hills, California)
ABSTRACT The present invention is directed to methods and compositions for acquiring nucleotide sequence information of target sequences using adaptors interspersed in target polynucleotides. The sequence information can be new, e.g. sequencing unknown nucleic acids, re-sequencing, or genotyping. The invention preferably includes methods for inserting a plurality of adaptors at spaced locations within a target polynucleotide or a fragment of a polynucleotide. Such adaptors may serve as platforms for interrogating adjacent sequences using various sequencing chemistries, such as those that identify nucleotides by primer extension, probe ligation, and the like. Encompassed in the invention are methods and compositions for the insertion of known adaptor sequences into target sequences, such that there is an interruption of contiguous target sequence with the adaptors. By sequencing both “upstream” and “downstream” of the adaptors, identification of entire target sequences may be accomplished.
FILED Wednesday, October 31, 2007
APPL NO 11/981605
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/64 (20130101)
C12N 15/66 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 2521/313 (20130101)
C12Q 2525/131 (20130101)
C12Q 2525/151 (20130101)
C12Q 2525/191 (20130101)
C12Q 2531/125 (20130101)
C12Q 2533/107 (20130101)
C12Q 2565/518 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 436/143333 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476063 Stayton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Patrick S. Stayton (Seattle, Washington);  Allan S. Hoffman (Seattle, Washington);  Anthony J. Convertine (Seattle, Washington);  Danielle Benoit (Rochester, New York);  Craig L. Duvall (Nashville, Tennessee);  Paul H. Johnson (Snohomish, Washington);  Anna S. Gall (Woodinville, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington);  PhaseRx, Inc. (Seattle, Washington)
INVENTOR(S) Patrick S. Stayton (Seattle, Washington);  Allan S. Hoffman (Seattle, Washington);  Anthony J. Convertine (Seattle, Washington);  Danielle Benoit (Rochester, New York);  Craig L. Duvall (Nashville, Tennessee);  Paul H. Johnson (Snohomish, Washington);  Anna S. Gall (Woodinville, Washington)
ABSTRACT Described herein are copolymers, and methods of making and utilizing such copolymers. Such copolymers have at least two blocks: a first block that has at least one unit that is hydrophilic at physiologic pH, and a second block that has hydrophobic groups. This second block further has at least one unit with a group that is anionic at about physiologic pH. The described copolymers are disruptive of a cellular membrane, including an extracellular membrane, an intracellular membrane, a vesicle, an organelle, an endosome, a liposome, or a red blood cell. Preferably, in certain instances, the copolymer disrupts the membrane and enters the intracellular environment. In specific examples, the copolymer is endosomolytic.
FILED Wednesday, May 13, 2009
APPL NO 12/992517
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Peptides
C07K 2319/10 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 293/00 (20130101)
C08F 293/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101) Original (OR) Class
C12N 15/111 (20130101)
C12N 2310/14 (20130101)
C12N 2310/315 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476089 Wu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Chao-ting Wu (Brookline, Massachusetts);  Brian Beliveau (Cambridge, Massachusetts)
ABSTRACT The present invention relates to methods of making linear nucleic acid probes using rolling circle amplification methods. In one aspect, an oligonucleotide template sequence is contacrted with one or more first primers, a first polymerase and first nucleotides under conditions that extend one or more hybridize primers to make a strand complementary to the oligonucleotide template sequence thereby forming a double stranded oligonucleotide. The double stranded oligonucleotide is circularized. A rolling circle template is obtained from the circularized double stranded oligonucleotide. The rolling circle template is contacted with one or more second primers, a second polymerase and second nucleotides under conditions that form a single stranded nucleic acid, and the single stranded nucleic acid is cleaved to form the plurality of nucleic acid probes.
FILED Thursday, October 18, 2012
APPL NO 13/654757
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6811 (20130101) Original (OR) Class
C12Q 1/6811 (20130101)
C12Q 2525/131 (20130101)
C12Q 2525/155 (20130101)
C12Q 2531/113 (20130101)
C12Q 2531/125 (20130101)
C12Q 2563/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476095 Vogelstein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Bert Vogelstein (Baltimore, Maryland);  Kenneth W. Kinzler (Baltimore, Maryland);  Nickolas Papadopoulos (Towson, Maryland);  Isaac Kinde (Beaumont, California)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Bert Vogelstein (Baltimore, Maryland);  Kenneth W. Kinzler (Baltimore, Maryland);  Nickolas Papadopoulos (Towson, Maryland);  Isaac Kinde (Beaumont, California)
ABSTRACT The identification of mutations that are present in a small fraction of DNA templates is essential for progress in several areas of biomedical research. Though massively parallel sequencing instruments are in principle well-suited to this task, the error rates in such instruments are generally too high to allow confident identification of rare variants. We here describe an approach that can substantially increase the sensitivity of massively parallel sequencing instruments for this purpose. One example of this approach, called “Safe-SeqS” for (Safe-Sequencing System) includes (i) assignment of a unique identifier (UID) to each template molecule; (ii) amplification of each uniquely tagged template molecule to create UID-families; and (iii) redundant sequencing of the amplification products. PCR fragments with the same UID are truly mutant (“super-mutants”) if ≧95% of them contain the identical mutation. We illustrate the utility of this approach for determining the fidelity of a polymerase, the accuracy of oligonucleotides synthesized in vitro, and the prevalence of mutations in the nuclear and mitochondrial genomes of normal cells.
FILED Thursday, April 12, 2012
APPL NO 14/111715
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 2535/122 (20130101)
C12Q 2563/179 (20130101)
C12Q 2565/514 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476096 Chinnaiyan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Arul Chinnaiyan (Plymouth, Michigan);  Dan Robinson (Ann Arbor, Michigan)
ABSTRACT Provided herein are kits, compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent gene fusions as diagnostic markers and clinical targets for hemangiopericytoma.
FILED Thursday, August 08, 2013
APPL NO 13/962590
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 1/6886 (20130101)
C12Q 2600/156 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56966 (20130101)
G01N 33/57407 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476097 Seidman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Jonathan G. Seidman (Milton, Massachusetts);  Christine E. Seidman (Milton, Massachusetts);  Daniel E. Herman (Cambridge, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jonathan G. Seidman (Milton, Massachusetts);  Christine E. Seidman (Milton, Massachusetts);  Daniel E. Herman (Cambridge, Massachusetts)
ABSTRACT Provided herein are diagnostic markers and methods for identifying a subject having an increased susceptibility for developing or having dilated cardiomyopathy. The method comprises determining if the subject has a mutation in the TTN nucleic as acid or titin polypeptide. Further provided herein are methods of treating subjects having or at risk of having dilated cardiomyopathy.
FILED Wednesday, April 11, 2012
APPL NO 14/111308
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/112 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476099 Spinella et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Michael Spinella (Hanover, New Hampshire);  Maroun J. Beyrouthy (Lebanon, New Hampshire)
ABSTRACT The present invention is a gene expression panel of chemotherapeutic drug-resistant cancer stem cells comprising RIN1, SOX15 and TLR4. In one embodiment the cancer stem cells are testicular cancer germ cells. The present invention provides for a kit and method for determining response to treatment with decitabine at low doses.
FILED Wednesday, July 31, 2013
APPL NO 14/416142
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7068 (20130101)
A61K 33/24 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/154 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57484 (20130101)
G01N 2333/4703 (20130101)
G01N 2333/4706 (20130101)
G01N 2333/70596 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476102 Bau et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Haim H. Bau (Swarthmore, Pennsylvania);  William R. Abrams (Merion, Pennsylvania);  Eran Geva (Brooklyn, New York);  Michael G. Mauk (Greenville, Delaware);  Changchun Liu (Bala Cynwyd, Pennsylvania);  Daneil Malamud (New York, New York);  Xianbo Ceiu (Beijing, China PRC)
ASSIGNEE(S) The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Haim H. Bau (Swarthmore, Pennsylvania);  William R. Abrams (Merion, Pennsylvania);  Eran Geva (Brooklyn, New York);  Michael G. Mauk (Greenville, Delaware);  Changchun Liu (Bala Cynwyd, Pennsylvania);  Daneil Malamud (New York, New York);  Xianbo Ceiu (Beijing, China PRC)
ABSTRACT Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments, isolate, amplify, and detect nucleic acid in a single chamber. In other embodiments, the devices are adapted to isolate and amplify nucleic acids in a reaction chamber, after which the nucleic acids may be communicated to a pervious medium—such as a lateral flow strip—where the user may label and detect the nucleic acids.
FILED Wednesday, February 15, 2012
APPL NO 14/001347
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5023 (20130101)
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 2200/10 (20130101)
B01L 2200/026 (20130101)
B01L 2300/087 (20130101)
B01L 2300/0681 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/1827 (20130101)
B01L 2300/1861 (20130101)
B01L 2400/065 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0644 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/703 (20130101) Original (OR) Class
C12Q 1/6806 (20130101)
C12Q 1/6844 (20130101)
C12Q 1/6844 (20130101)
C12Q 2537/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476103 Johnson et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S) Centers for Disease Control and Prevention (Atlanta, Georgia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Jeffrey A. Johnson (Stone Mountain, Georgia);  Walid M. Heneine (Atlanta, Georgia)
ABSTRACT Disclosed are compositions including primers and probes, which are capable of interacting with the disclosed nucleic acids, such as the nucleic acids encoding the reverse transcriptase or protease of HIV as disclosed herein. Thus, provided is an oligonucleotide comprising any one of the nucleotide sequences set for in SEQ ID NOS:1-89, and 96-104. Also provided are the oligonucleotides consisting of the nucleotides as set forth in SEQ ID NOS:1-89, and 96-104. Each of the disclosed oligonucleotides is a probe or a primer. Also provided are mixtures of primers and probes and for use in RT-PCR and primary PCR reactions disclosed herein. Provided are methods for the specific detection of several mutations in HIV. Mutations in both the reverse transcriptase and the protease of HIV can be detected using the methods described herein.
FILED Monday, October 21, 2013
APPL NO 14/059085
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/703 (20130101) Original (OR) Class

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 435/975 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476813 Couch
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S) Robin Couch (Bristow, Virginia)
ASSIGNEE(S) George Mason University (Fairfax, Virginia)
INVENTOR(S) Robin Couch (Bristow, Virginia)
ABSTRACT Apparatus and methods are disclosed for the collection and analysis of analytes from samples. In one embodiment an extraction chamber is provided that includes a sample holder and an extraction lid that allows for simultaneous multifiber solid phase microextraction of analytes from a sample held in the sample holder. Methods of collection and analysis include using simultaneous multifiber solid phase microextraction of analytes from a sample.
FILED Wednesday, April 04, 2012
APPL NO 13/439290
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/405 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 436/24 (20150115)
Y10T 436/255 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476819 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) Tza-Huei Jeff Wang (Timonium, Maryland);  Kelvin Jeng-Fang Liu (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Tza-Huei Jeff Wang (Timonium, Maryland);  Kelvin Jeng-Fang Liu (Baltimore, Maryland)
ABSTRACT A method of separating, detecting and determining a size of each of a plurality of particles in a fluid includes compelling the fluid to flow through a fluid channel such that larger particles of the plurality of particles travel through the fluid channel faster than smaller particles of the plurality of particles; illuminating a detection zone of the fluid channel substantially uniformly across an entire cross section of the fluid channel such that each of the plurality of particles passes through illumination light upon passing through the detection zone; detecting each of the plurality of particles based on corresponding responses to the illuminating to determine a time that each of the plurality of particles passes through the detection zone; and determining a size of each of the plurality of particles based on the time that each of the plurality of particles passes through the detection zone.
FILED Wednesday, October 19, 2011
APPL NO 13/822986
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 2565/629 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/0255 (20130101)
G01N 15/1484 (20130101) Original (OR) Class
G01N 21/645 (20130101)
G01N 33/48 (20130101)
G01N 2015/149 (20130101)
G01N 2015/1486 (20130101)
G01N 2015/1493 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476830 Pantazis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Periklis Pantazis (Pasadena, California);  Ye Pu (Pasadena, California);  Demetri Psaltis (St-Sulpice, Switzerland);  John H. Hong (Pasadena, California);  Scott E. Fraser (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Periklis Pantazis (Pasadena, California);  Ye Pu (Pasadena, California);  Demetri Psaltis (St-Sulpice, Switzerland);  John H. Hong (Pasadena, California);  Scott E. Fraser (Pasadena, California)
ABSTRACT Second harmonic nanoprobes for imaging biological samples and a method of using such probes to monitor the dynamics of biological process using a field resonance enhanced second harmonic (FRESH) technique are provided. The second harmonic generating (SHG) nanoprobes are comprised of various kinds of nanocrystals that do not possess an inversion symmetry and therefore are capable of generating second harmonic signals that can then be detected by conventional two-photon microscopy for in vivo imaging of biological processes and structures such as cell signaling, neuroimaging, protein conformation probing, DNA conformation probing, gene transcription, virus infection and replication in cells, protein dynamics, tumor imaging and cancer therapy evaluation and diagnosis as well as quantification in optical imaging.
FILED Wednesday, November 21, 2007
APPL NO 11/944264
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 20/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/636 (20130101) Original (OR) Class

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/37 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476839 Ranieri et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Nicola Ranieri (Maineville, Ohio);  Mark R. Witkowski (West Chester, Ohio);  William G. Fateley (Green Valley, Arizona);  Robert Hammaker (Manhattan, Kansas)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Nicola Ranieri (Maineville, Ohio);  Mark R. Witkowski (West Chester, Ohio);  William G. Fateley (Green Valley, Arizona);  Robert Hammaker (Manhattan, Kansas)
ABSTRACT Featured are a device (20) and method for the detection of counterfeit pharmaceuticals and/or packaging therefore. Counterfeit pharmaceuticals are detected by visual inspection upon exposing a suspected counterfeit pharmaceutical to one or more light sources having different wavelengths, and observing the differences in color and/or brightness between the suspected counterfeit and a genuine pharmaceutical/packaging. In further embodiments, a image acquisition device acquires an image showing color and/or other visual effect(s) brightness of the suspect counterfeit and this image is compared to an image of a authentic pharmaceutical/packaging.
FILED Wednesday, March 31, 2010
APPL NO 13/262371
ART UNIT 2483 — Recording and Compression
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/02 (20130101)
G01J 3/10 (20130101)
G01J 3/32 (20130101)
G01J 3/50 (20130101)
G01J 3/0272 (20130101)
G01J 3/501 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 21/3563 (20130101)
G01N 21/9508 (20130101) Original (OR) Class
G01N 2201/0221 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00577 (20130101)
G06K 9/2018 (20130101)
G06K 9/4652 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476851 Schoenfisch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of North Carolina Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)
INVENTOR(S) Mark H. Schoenfisch (Chapel Hill, North Carolina);  Jae Ho Shin (Chapel Hill, North Carolina)
ABSTRACT The presently disclosed subject matter relates to sensors for measuring an amount of a gaseous species in a sample. The sensors comprise a gas permeable polysiloxane network membrane, comprising both alkyl and fluorinated alkyl groups. In some embodiments, the polysiloxane network can be formed from the co-condensation of a mixture of an alkylalkoxysilane and a fluorosilane. The presently disclosed subject matter also relates to methods of making the sensors, methods of selectively measuring an amount of a gaseous species, such as nitric oxide, in a sample, and to compositions comprising the polysiloxane networks.
FILED Monday, September 09, 2013
APPL NO 14/020919
ART UNIT 1759 — Recording and Compression
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4045 (20130101)
G01N 27/4072 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476856 Pamula et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Advanced Liquid Logic Inc. (San Diego, California);  Duke University (Durham, North Carolina)
ASSIGNEE(S) ADVANCED LIQUID LOGIC, INC. (San Diego, California);  DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Vamsee K. Pamula (Cary, North Carolina);  Vijay Srinivasan (Cary, North Carolina);  Michael G. Pollack (Durham, North Carolina);  Richard B. Fair (Durham, North Carolina)
ABSTRACT A method of detecting a target analyte in a sample, including executing electrowetting-mediated droplet operations and thereby: combining one or more immunoassay reagent droplets comprising magnetically-responsive beads having affinity for the target analyte with one or more sample droplets potentially comprising the target analyte to yield a first combined droplet; beginning with the combined droplet, effecting a droplet-based washing protocol to wash the magnetically-responsive beads to yield a first washed droplet comprising the washed magnetically responsive beads; and combining the droplet comprising the washed magnetically responsive beads with a droplet comprising a reporter molecule having affinity for target analyte captured on the magnetically-responsive beads to yield a second combined droplet; beginning with the second combined droplet, effecting a droplet-based washing protocol to wash the magnetically-responsive beads to yield a second washed droplet comprising the washed magnetically responsive beads; detecting a signal from the second washed droplet which corresponds to the presence, absence and/or quantity of the analyte in the sample.
FILED Thursday, May 09, 2013
APPL NO 13/890715
ART UNIT 1677 — Recording and Compression
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/72 (20130101) Original (OR) Class
G01N 27/745 (20130101)
G01N 33/54326 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477233 Ismagilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) Rustem F. Ismagilov (Chicago, Illinois);  Bo Zheng (Chicago, Illinois);  Cory J. Gerdts (Chicago, Illinois)
ASSIGNEE(S) THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S) Rustem F. Ismagilov (Chicago, Illinois);  Bo Zheng (Chicago, Illinois);  Cory J. Gerdts (Chicago, Illinois)
ABSTRACT A microfluidic system with a plurality of sequential T-junctions for performing reactions in a plurality of droplets (plugs) of micro- to femtoliter volumes is disclosed. The microfluidic system is configured such that the plurality of plugs are flowing through a loading component, with the loading component splitting the plurality of plugs at each of the plurality of downstream T-junctions and each inlet of the plurality of detachable holding components is configured to be operably coupled with at least one of outlets of the plurality of downstream T-junctions so that the holding components received a plurality of split plugs in the immiscible carrier fluid from the loading component.
FILED Friday, July 01, 2005
APPL NO 11/174298
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 5/0471 (20130101)
B01F 13/0071 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0059 (20130101)
B01J 2219/00522 (20130101)
B01J 2219/00585 (20130101)
B01J 2219/00599 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0293 (20130101)
B01L 3/502746 (20130101)
B01L 3/502784 (20130101)
B01L 2200/0673 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 35/08 (20130101)
G01N 2035/1034 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 7/0694 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 137/0318 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478026 Jensen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) MUSC Foundation for Research Development (Charleston, South Carolina);  Golbarg Tarighat Saber (Charleston, South Carolina)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina)
INVENTOR(S) Jens Jensen (Charleston, South Carolina);  Ali Tabesh (Charleston, South Carolina);  Joseph Helpern (Sullivans Island, South Carolina)
ABSTRACT One aspect of the present disclosure relates to a system that can determine a kurtosis diffusion orientation distribution function (dODF) that can, for example, be used with diffusional kurtosis imaging fiber tractography (DKI-FT). The system can include a non-transitory memory storing computer-executable instructions and a processor that executes the computer-executable instructions to perform the following operations. Diffusion magnetic resonance imaging (dMRI) data can be received. Based on the dMRI data, a diffusion tensor (DT) and a diffusional kurtosis tensor (DKT) can be determined. A kurtosis dODF can be determined for the dMRI data based on the DT and the DKT. The kurtosis dODF extends a Gaussian approximation of the DT to include non-Gaussian corrections of the DKT.
FILED Tuesday, March 31, 2015
APPL NO 14/673991
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101)
A61B 5/168 (20130101)
A61B 5/4088 (20130101)
A61B 5/4094 (20130101)
A61B 2576/026 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/56341 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/0081 (20130101)
G06T 2207/10092 (20130101)
G06T 2207/30016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478405 Coon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Joshua J. Coon (Middleton, Wisconsin);  Graeme C. McAlister (Madison, Wisconsin)
ABSTRACT Described herein are methods and systems related to the use of the pre-existing ion injection pathway of a mass spectrometer to perform beam-type collision-activated dissociation, as well as other dissociation methods. The methods can be practiced using a wide range of mass spectrometer configurations and allows MSn experiments to be performed on very basic mass spectrometers, even those without secondary mass analyzers and/or collision cells. Following injection and selection of a particular ion type or population, that population can be fragmented via beam-type collision-activated dissociation (CAD), as well as other dissociation methods, using the pre-existing ion injection pathway or inlet of a mass spectrometer. For CAD applications, this is achieved by transmitting the ions back along the ion injection pathway with a high degree of kinetic energy. As the ions pass into the higher pressure regions located in or near the atmospheric pressure inlet, the ions are fragmented and then trapped. Following fragmentation and trapping, the ions can either be re-injected into the primary ion selection device or sent on to a secondary mass analyzer.
FILED Monday, May 04, 2015
APPL NO 14/703643
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/004 (20130101)
H01J 49/10 (20130101) Original (OR) Class
H01J 49/0045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 09474271 John et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute on Aging (NIA)
National Science Foundation (NSF)
APPLICANT(S) Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York);  The Curators of The University of Missouri (Columbia, Missouri);  University of North Texas (Denton, Texas)
INVENTOR(S) George John (New York, New York);  Subbiah Nagarajan (New York, New York);  Kent Chapman (Denton, Texas);  Lionel Faure (Flower Mound, Texas);  Peter Koulen (Leawood, Kansas)
ABSTRACT A method for enhancing amidohydrolase activity of Fatty Acid Amide Hydrolase (FAAH) is disclosed. The method comprising administering a phenoxyacylethanolamide that causes the enhanced activity. The enhanced activity can have numerous effects on biological organisms including, for example, enhancing the growth of certain seedlings. The subject matter disclosed herein relates to enhancers of amidohydrolase activity.
FILED Friday, January 17, 2014
APPL NO 14/761826
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 37/20 (20130101) Original (OR) Class
A01N 39/04 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474448 Ghosh et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Kunal Ghosh (Mountain View, California);  Laurie Burns (Menlo Park, California);  Abbas El Gamal (Palo Alto, California);  Mark J. Schnitzer (Palo Alto, California);  Eric Cocker (Palo Alto, California);  Tatt Wei Ho (Stanford, California)
ABSTRACT Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.
FILED Thursday, October 15, 2015
APPL NO 14/884543
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/0071 (20130101) Original (OR) Class
A61B 5/0082 (20130101)
A61B 5/489 (20130101)
A61B 2503/40 (20130101)
A61B 2503/42 (20130101)
A61B 2562/04 (20130101)
A61B 2562/0233 (20130101)
A61B 2576/026 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/0087 (20130101)
G02B 21/0008 (20130101)
G02B 21/008 (20130101)
G02B 21/16 (20130101)
G02B 21/36 (20130101)
G02B 21/361 (20130101)
G02B 21/362 (20130101)
G02B 21/365 (20130101)
G02B 27/141 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/30016 (20130101)
G06T 2207/30101 (20130101)

Pictorial Communication, e.g Television
H04N 5/2254 (20130101)
H04N 5/2256 (20130101)
H04N 5/23296 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475023 Bindra et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
Directorate of Environmental Research and Education (ERE)
APPLICANT(S) Hitesh Bindra (Fort Lee, New Jersey);  Pablo Bueno (New York, New York)
ASSIGNEE(S) The Research Foundation of the City University of New York (New York, New York)
INVENTOR(S) Hitesh Bindra (Fort Lee, New Jersey);  Pablo Bueno (New York, New York)
ABSTRACT Methods and systems for optimizing the process of heat and/or mass transfer operations in packed beds and embodiments of applications of the methods are disclosed herein below. In one instance, the method results in the profile of the quantity representative of the heat and/or mass transfer operation having a propagating substantially sharp front.
FILED Tuesday, January 10, 2012
APPL NO 14/234286
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/04 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0006 (20130101) Original (OR) Class

Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles
F01K 23/10 (20130101)

Methods of Steam Generation; Steam Boilers
F22B 1/028 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 17/02 (20130101)
F28D 20/00 (20130101)
F28D 20/0056 (20130101)
F28D 2020/0069 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 20/16 (20130101)
Y02E 60/142 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475039 Narula et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Chaitanya K. Narula (Knoxville, Tennessee);  Xiaofan Yang (Knoxville, Tennessee)
ABSTRACT A catalyst composition includes a heterobimetallic zeolite characterized by a chabazite structure loaded with copper ions and at least one trivalent metal ion other than Al3+. The catalyst composition decreases NOx emissions in diesel exhaust and is suitable for operation in a catalytic converter.
FILED Thursday, March 19, 2015
APPL NO 14/662954
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/9418 (20130101)
B01D 2255/50 (20130101)
B01D 2255/20738 (20130101)
B01D 2255/20761 (20130101)
B01D 2258/012 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 29/061 (20130101)
B01J 29/064 (20130101)
B01J 29/068 (20130101)
B01J 29/072 (20130101)
B01J 29/76 (20130101) Original (OR) Class
B01J 29/763 (20130101)
B01J 29/783 (20130101)
B01J 29/7049 (20130101)
B01J 29/7065 (20130101)
B01J 2229/186 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 39/02 (20130101)
C01B 39/06 (20130101)
C01B 39/026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475690 Sumant et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Anirudha V. Sumant (Plainfield, Illinois);  Federico Buja (Rotterdam, Netherlands);  Willem Merlijn van Spengen (Leiden, Netherlands)
ABSTRACT Nanocrystalline diamond coatings exhibit stress in nano/micro-electro mechanical systems (MEMS). Doped nanocrstalline diamond coatings exhibit increased stress. A carbide forming metal coating reduces the in-plane stress. In addition, without any metal coating, simply growing UNCD or NCD with thickness in the range of 3-4 micron also reduces in-plane stress significantly. Such coatings can be used in MEMS applications.
FILED Tuesday, May 20, 2014
APPL NO 14/283098
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0024 (20130101) Original (OR) Class

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/0038 (20130101)
B81C 2201/013 (20130101)
B81C 2201/017 (20130101)
B81C 2201/0171 (20130101)
B81C 2201/0176 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475706 Policke et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Babcock and Wilcox Technical Services Group, Inc. (Lynchburg, Virginia)
ASSIGNEE(S) BWXT Technical Services Group, Inc. (Lynchburg, Virginia)
INVENTOR(S) Timothy A Policke (Forest, Virginia);  Scott B Aase (Aiken, South Carolina);  William R Stagg (Southern Pines, North Carolina)
ABSTRACT The present invention relates generally to the field of medical isotope production by fission of uranium-235 and the fuel utilized therein (e.g., the production of suitable Low Enriched Uranium (LEU is uranium having 20 weight percent or less uranium-235) fuel for medical isotope production) and, in particular to a method for producing LEU fuel and a LEU fuel product that is suitable for use in the production of medical isotopes. In one embodiment, the LEU fuel of the present invention is designed to be utilized in an Aqueous Homogeneous Reactor (AHR) for the production of various medical isotopes including, but not limited to, molybdenum-99, cesium-137, iodine-131, strontium-89, xenon-133 and yttrium-90.
FILED Wednesday, October 24, 2012
APPL NO 13/659419
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 43/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475998 Gordon et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Ceramatec, Inc. (Salt Lake City, Utah)
ASSIGNEE(S) CERAMATEC, INC. (Salt Lake City, Utah)
INVENTOR(S) John Howard Gordon (Salt Lake City, Utah);  Javier Alvare (Cottonwood Heights, Utah)
ABSTRACT Alkali metals and sulfur may be recovered from alkali monosulfide and polysulfides in an electrolytic process that utilizes an electrolytic cell having an alkali ion conductive membrane. An anolyte solution includes an alkali monosulfide, an alkali polysulfide, or a mixture thereof and a solvent that dissolves elemental sulfur. A catholyte includes molten alkali metal. Applying an electric current oxidizes sulfide and polysulfide in the anolyte compartment, causes alkali metal ions to pass through the alkali ion conductive membrane to the catholyte compartment, and reduces the alkali metal ions in the catholyte compartment. Liquid sulfur separates from the anolyte solution and may be recovered. The electrolytic cell is operated at a temperature where the formed alkali metal and sulfur are molten.
FILED Friday, March 14, 2014
APPL NO 14/210891
ART UNIT 1754 — Miscellaneous Articles, Stock Material
CURRENT CPC
Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 32/02 (20130101) Original (OR) Class

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/00 (20130101)

Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor
C25C 1/02 (20130101)
C25C 3/02 (20130101)
C25C 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476007 Ajayi et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Oyelayo O. Ajayi (Oswego, Illinois);  Maria De La Lorenzo-Martin (Darian, Illinois);  George R. Fenske (Downers Grove, Illinois)
ABSTRACT An article of method of manufacture of a low friction tribological film on a substrate. The article includes a substrate of a steel or ceramic which has been tribologically processed with a lubricant containing selected additives and the additives, temperature, load and time of processing can be selectively controlled to bias formation of a film on the substrate where the film is an amorphous structure exhibiting highly advantageous low friction properties.
FILED Thursday, September 26, 2013
APPL NO 14/038121
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 177/00 (20130101) Original (OR) Class
C10M 2201/0403 (20130101)
C10M 2203/003 (20130101)
C10M 2205/0285 (20130101)
C10M 2227/066 (20130101)

Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions
C10N 2210/01 (20130101)
C10N 2210/06 (20130101)
C10N 2230/06 (20130101)
C10N 2250/141 (20130101)
C10N 2280/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476036 Shasky et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Jeffrey Shasky (Davis, California);  Amanda Fischer (Davis, California);  Suchindra Maiyuran (Gold River, California)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Jeffrey Shasky (Davis, California);  Amanda Fischer (Davis, California);  Suchindra Maiyuran (Gold River, California)
ABSTRACT The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the compositions.
FILED Thursday, August 23, 2012
APPL NO 14/238431
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/38 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2437 (20130101) Original (OR) Class
C12N 9/2445 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101)
C12P 19/14 (20130101)

Enzymes
C12Y 302/01004 (20130101)
C12Y 302/01021 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/52 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476040 Mackenzie et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
APPLICANT(S) Sally Ann Mackenzie (Lincoln, Nebraska);  Roberto De la Rosa Santamaria (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
INVENTOR(S) Sally Ann Mackenzie (Lincoln, Nebraska);  Roberto De la Rosa Santamaria (Lincoln, Nebraska)
ABSTRACT The present invention provides methods for obtaining plants that exhibit useful traits by transient suppression of the MSH1 gene of the plants. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants.
FILED Wednesday, May 02, 2012
APPL NO 13/462216
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 1/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 15/8218 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476067 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Algenol Biofuels Inc. (Fort Myers, Florida)
ASSIGNEE(S) Algenol Biotech LLC (Fort Myers, Florida)
INVENTOR(S) Kui Wang (Fort Myers, Florida);  Tuo Shi (San Diego, California)
ABSTRACT A plasmid vector for the production of compounds in cyanobacteria is described which is capable of being efficiently transformed to and replicating in a broad range of cyanobacterial species.
FILED Friday, June 12, 2015
APPL NO 14/737911
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/195 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/70 (20130101)
C12N 15/74 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/06 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476068 Mielgo et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Iñaki Mielgo (Sevilla, Spain);  Patrick Mulvihill (Weldon Spring, Missouri)
ASSIGNEE(S) Abengoa Bioenergy New Technologies, LLC (Chesterfield, Missouri)
INVENTOR(S) Iñaki Mielgo (Sevilla, Spain);  Patrick Mulvihill (Weldon Spring, Missouri)
ABSTRACT A process is disclosed for producing a feed co-product by ethanol fermentation of plant matter comprising starch and another polysaccharide selected from the group consisting of hemicellulose and cellulose. The process comprises: (i) carrying out a primary fermentation process, distilling the primary fermentation mixture to form a primary feed co-product derived from the fermentation of the primary fermentation mixture and a primary distillate product comprising ethanol and (ii) carrying out a secondary fermentation process and distilling the secondary fermentation mixture to form the modified feed co-product and a secondary distillate product comprising ethanol.
FILED Thursday, November 04, 2010
APPL NO 13/266231
ART UNIT 1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Treatment, e.g Preservation, of Flour or Dough, e.g by Addition of Materials; Baking; Bakery Products; Preservation Thereof
A21D 2/36 (20130101)

Fodder
A23K 1/007 (20130101)
A23K 1/146 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/08 (20130101)
C12P 7/10 (20130101) Original (OR) Class
C12P 7/14 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476129 Lewis et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Nathan S. Lewis (La Canada Flintridge, California);  Joshua M. Spurgeon (Los Angeles, California)
ABSTRACT The solar fuels generator includes an ionically conductive separator between a gaseous first phase and a second phase. A photoanode uses one or more components of the first phase to generate cations during operation of the solar fuels generator. A cation conduit is positioned provides a pathway along which the cations travel from the photoanode to the separator. The separator conducts the cations. A second solid cation conduit conducts the cations from the separator to a photocathode.
FILED Tuesday, April 02, 2013
APPL NO 13/855515
ART UNIT 1756 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/003 (20130101)
C25B 9/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476355 Little et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) David A. Little (Chuluota, Florida);  Gerard McQuiggan (Orlando, Florida);  David L. Wasdell (Winter Park, Florida)
ASSIGNEE(S) SIEMENS ENERGY, INC. (Orlando, Florida)
INVENTOR(S) David A. Little (Chuluota, Florida);  Gerard McQuiggan (Orlando, Florida);  David L. Wasdell (Winter Park, Florida)
ABSTRACT A midframe portion (213) of a gas turbine engine (210) is presented, and includes a compressor section (212) configured to discharge an air flow (211) directed in a radial direction from an outlet of the compressor section (212). Additionally, the midframe portion (213) includes a manifold (214) to directly couple the air flow (211) from the compressor section (212) outlet to an inlet of a respective combustor head (218) of the midframe portion (213).
FILED Wednesday, February 29, 2012
APPL NO 13/408147
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476412 Marion, III et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) John E. Marion, III (Livermore, California);  Jane P. Bearinger (Livermore, California);  Thomas S. Wilson (San Leandro, California);  Duncan J. Maitland (College Station, Texas)
ABSTRACT A resistively heated shape memory polymer device is made by providing a rod, sheet or substrate that includes a resistive medium. The rod, sheet or substrate is coated with a first shape memory polymer providing a coated intermediate unit. The coated intermediate unit is in turn coated with a conductive material providing a second intermediate unit. The second coated intermediate unit is in turn coated with an outer shape memory polymer. The rod, sheet or substrate is exposed and an electrical lead is attached to the rod, sheet or substrate. The conductive material is exposed and an electrical lead is attached to the conductive material.
FILED Thursday, March 14, 2013
APPL NO 13/829183
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 2311/005 (20130101)

Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/065 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 29/49002 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476546 Croteau et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) GOODRICH CORPORATION (Charlotte, North Carolina)
ASSIGNEE(S) Goodrich Corporation (Charlotte, North Carolina)
INVENTOR(S) Paul F. Croteau (Columbia, Connecticut);  Andrzej E. Kuczek (Bristol, Connecticut);  Wenping Zhao (Glastonbury, Connecticut)
ABSTRACT A high-pressure vessel is provided. The high-pressure vessel may comprise a first chamber defined at least partially by a first wall, and a second chamber defined at least partially by the first wall. The first chamber and the second chamber may form a curved contour of the high-pressure vessel. A modular tank assembly is also provided, and may comprise a first mid tube having a convex geometry. The first mid tube may be defined by a first inner wall, a curved wall extending from the first inner wall, and a second inner wall extending from the curved wall. The first inner wall may be disposed at an angle relative to the second inner wall. The first mid tube may further be defined by a short curved wall opposite the curved wall and extending from the second inner wall to the first inner wall.
FILED Friday, March 27, 2015
APPL NO 14/671787
ART UNIT 3728 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 1/00 (20130101)
F17C 1/14 (20130101) Original (OR) Class
F17C 2201/0109 (20130101)
F17C 2201/0152 (20130101)
F17C 2203/0617 (20130101)
F17C 2203/0639 (20130101)
F17C 2203/0646 (20130101)
F17C 2203/0663 (20130101)
F17C 2209/221 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476592 Berry
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Jonathan Dwight Berry (Simpsonville, South Carolina)
ABSTRACT A combustion system uses a fuel nozzle with an inner wall having a fuel inlet in fluid communication with a fuel outlet in a fuel cartridge. The inner wall defines a mounting location for inserting the fuel cartridge. A pair of annular lip seals around the cartridge outer wall on both sides of the fuel outlet seals the fuel passage between the fuel inlet and the fuel outlet.
FILED Thursday, September 19, 2013
APPL NO 13/956921
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/10 (20130101)
F23R 3/286 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476685 Mace et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Jonathan L. Mace (Los Alamos, New Mexico);  Gerald J. Seitz (El Rancho, New Mexico);  Lawrence E. Bronisz (Los Alamos, New Mexico)
ABSTRACT Detonation control modules and detonation control circuits are provided herein. A trigger input signal can cause a detonation control module to trigger a detonator. A detonation control module can include a timing circuit, a light-producing diode such as a laser diode, an optically triggered diode, and a high-voltage capacitor. The trigger input signal can activate the timing circuit. The timing circuit can control activation of the light-producing diode. Activation of the light-producing diode illuminates and activates the optically triggered diode. The optically triggered diode can be coupled between the high-voltage capacitor and the detonator. Activation of the optically triggered diode causes a power pulse to be released from the high-voltage capacitor that triggers the detonator.
FILED Monday, January 14, 2013
APPL NO 14/370207
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 25/34 (20130101)

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/263 (20130101)
E21B 43/1185 (20130101)
E21B 47/123 (20130101)

Ignition; Extinguishing-devices
F23Q 21/00 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 3/02 (20130101)
F42B 3/10 (20130101)
F42B 3/113 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 15/42 (20130101)

Blasting
F42D 1/02 (20130101)
F42D 1/05 (20130101)
F42D 1/042 (20130101) Original (OR) Class
F42D 1/045 (20130101)
F42D 3/00 (20130101)
F42D 3/04 (20130101)
F42D 3/06 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49826 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476747 Barty et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Christopher P. J. Barty (Hayward, California);  John C. Post (Livermore, California);  Edwin Jones (Carmel Valley, California)
ABSTRACT A laser-based mono-energetic gamma-ray source is used to provide non-destructive and non-intrusive, quantitative determination of the absolute amount of a specific isotope contained within pipe as part of a moving fluid or quasi-fluid material stream.
FILED Monday, December 07, 2015
APPL NO 14/961807
ART UNIT 2884 — Optics
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 5/346 (20130101)
B07C 5/3416 (20130101)

Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/7042 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/10 (20130101)
G01N 23/066 (20130101)
G01N 23/221 (20130101)
G01N 2223/043 (20130101)
G01N 2223/074 (20130101)
G01N 2223/626 (20130101)
G01N 2223/639 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 5/0016 (20130101)
G01V 5/0091 (20130101)

X-ray Technique
H05G 2/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476768 DeFlores et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Lauren DeFlores (Cambridge, Massachusetts);  Andrei Tokmakoff (Lexington, Massachusetts)
ABSTRACT The present invention relates to a system and methods for acquiring two-dimensional Fourier transform (2D FT) spectra. Overlap of a collinear pulse pair and probe induce a molecular response which is collected by spectral dispersion of the signal modulated probe beam. Simultaneous collection of the molecular response, pulse timing and characteristics permit real time phasing and rapid acquisition of spectra. Full spectra are acquired as a function of pulse pair timings and numerically transformed to achieve the full frequency-frequency spectrum. This method demonstrates the ability to acquire information on molecular dynamics, couplings and structure in a simple apparatus. Multi-dimensional methods can be used for diagnostic and analytical measurements in the biological, biomedical, and chemical fields.
FILED Wednesday, July 31, 2013
APPL NO 13/955158
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101) Original (OR) Class
G01J 3/2803 (20130101)
G01J 3/2823 (20130101)
G01J 3/4531 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/35 (20130101)
G01N 2021/3595 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476780 Keyser et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Matthew Allen Keyser (Arvada, Colorado);  Ahmad Pesaran (Boulder, Colorado);  Mark Alan Mihalic (Jamestown, Colorado);  John Ireland (Denver, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Matthew Allen Keyser (Arvada, Colorado);  Ahmad Pesaran (Boulder, Colorado);  Mark Alan Mihalic (Jamestown, Colorado);  John Ireland (Denver, Colorado)
ABSTRACT Large volume calorimeters (100) and small volume, or cell, calorimeters (700), as well as methods of making and using the same, are provided.
FILED Friday, March 09, 2012
APPL NO 14/004319
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 17/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476785 Ivanov et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Ilia N. Ivanov (Knoxville, Tennessee);  David B. Geohegan (Knoxville, Tennessee)
ABSTRACT The present invention, in one embodiment, provides a method of measuring pressure or temperature using a sensor including a sensor element composed of a plurality of carbon nanotubes. In one example, the resistance of the plurality of carbon nanotubes is measured in response to the application of temperature or pressure. The changes in resistance are then recorded and correlated to temperature or pressure. In one embodiment, the present invention provides for independent measurement of pressure or temperature using the sensors disclosed herein.
FILED Tuesday, September 24, 2013
APPL NO 14/035097
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 30/00 (20130101)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 7/00 (20130101)
G01K 7/18 (20130101)
G01K 7/021 (20130101)
G01K 7/028 (20130101)
G01K 2211/00 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/20 (20130101)
G01L 9/00 (20130101)
G01L 9/0001 (20130101)
G01L 9/0002 (20130101)
G01L 9/0005 (20130101)
G01L 19/00 (20130101) Original (OR) Class

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/742 (20130101)
Y10S 977/955 (20130101)
Y10S 977/956 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476816 Schmitz et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Hysitron, Inc. (Eden Prairie, Massachusetts)
ASSIGNEE(S) Hysitron, Inc. (Eden Prairie, Minnesota)
INVENTOR(S) Roger William Schmitz (Hutchinson, Minnesota);  Yunje Oh (Medina, Minnesota)
ABSTRACT A heating assembly configured for use in mechanical testing at a scale of microns or less. The heating assembly includes a probe tip assembly configured for coupling with a transducer of the mechanical testing system. The probe tip assembly includes a probe tip heater system having a heating element, a probe tip coupled with the probe tip heater system, and a heater socket assembly. The heater socket assembly, in one example, includes a yoke and a heater interface that form a socket within the heater socket assembly. The probe tip heater system, coupled with the probe tip, is slidably received and clamped within the socket.
FILED Wednesday, November 14, 2012
APPL NO 14/358065
ART UNIT 3742 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/40 (20130101) Original (OR) Class
G01N 3/42 (20130101)
G01N 2203/0226 (20130101)
G01N 2203/0282 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 30/02 (20130101)
G01Q 30/10 (20130101)
G01Q 60/366 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 3/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477040 Skogen
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Erik J. Skogen (Albuquerque, New Mexico)
ABSTRACT The present invention includes a high-speed, high-saturation power detector (e.g., a photodiode) compatible with a relatively simple monolithic integration process. In particular embodiments, the photodiode includes an intrinsic bulk absorption region, which is grown above a main waveguide core including a number of quantum wells (QWs) that are used as the active region of a phase modulator. The invention also includes methods of fabricating integrated photodiode and waveguide assemblies using a monolithic, simplified process.
FILED Thursday, July 16, 2015
APPL NO 14/801257
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/132 (20130101) Original (OR) Class
G02B 6/1347 (20130101)
G02B 2006/12123 (20130101)
G02B 2006/12128 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/1844 (20130101)
H01L 31/02327 (20130101)
H01L 31/035272 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477526 Johnson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Energy (DOE)
APPLICANT(S) NVIDIA Corporation (Santa Clara, California)
ASSIGNEE(S) NVIDIA Corporation (Santa Clara, California)
INVENTOR(S) Daniel Robert Johnson (Austin, Texas);  Minsoo Rhu (Austin, Texas);  James M. O'Connor (Austin, Texas);  Stephen William Keckler (Austin, Texas)
ABSTRACT A system, method, and computer program product are provided for providing prioritized access for multithreaded processing. The method includes the steps of allocating threads to process a workload and assigning a set of priority tokens to at least a portion of the threads. Access to a resource, by each one of the threads, is based on the priority token assigned to the thread and the threads are executed by a multithreaded processor to process the workload.
FILED Friday, January 03, 2014
APPL NO 14/147395
ART UNIT 2195 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/48 (20130101)
G06F 9/5016 (20130101)
G06F 9/5027 (20130101) Original (OR) Class
G06F 2209/5021 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 60/142 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477605 Loh et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
INVENTOR(S) Gabriel H. Loh (Bellevue, Washington);  James M. O'Connor (Austin, Texas)
ABSTRACT A system includes a first memory and a device coupleable to the first memory. The device includes a second memory to cache data from the first memory. The second memory includes a plurality of rows, each row including a corresponding set of compressed data blocks of non-uniform sizes and a corresponding set of tag blocks. Each tag block represents a corresponding compressed data block of the row. The device further includes decompression logic to decompress data blocks accessed from the second memory. The device further includes compression logic to compress data blocks to be stored in the second memory.
FILED Thursday, July 11, 2013
APPL NO 13/939377
ART UNIT 2137 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0851 (20130101)
G06F 12/0866 (20130101) Original (OR) Class
G06F 12/0895 (20130101)
G06F 2212/401 (20130101)
G06F 2212/1024 (20130101)
G06F 2212/1036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477628 Knies et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) INTEL CORPORATION (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Allan D. Knies (Burlingame, California);  David Pardo Keppel (Seattle, Washington);  Dong Hyuk Woo (Campbell, California);  Joshua B. Fryman (Corvallis, Oregon)
ABSTRACT A collective communication apparatus and method for parallel computing systems. For example, one embodiment of an apparatus comprises a plurality of processor elements (PEs); collective interconnect logic to dynamically form a virtual collective interconnect (VCI) between the PEs at runtime without global communication among all of the PEs, the VCI defining a logical topology between the PEs in which each PE is directly communicatively coupled to a only a subset of the remaining PEs; and execution logic to execute collective operations across the PEs, wherein one or more of the PEs receive first results from a first portion of the subset of the remaining PEs, perform a portion of the collective operations, and provide second results to a second portion of the subset of the remaining PEs.
FILED Saturday, September 28, 2013
APPL NO 14/040676
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/52 (20130101)
G06F 13/4068 (20130101) Original (OR) Class
G06F 15/17318 (20130101)
G06F 15/17325 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477682 Bent et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) EMC Corporation (Hopkinton, Massachusetts)
ASSIGNEE(S) EMC Corporation (Hopkinton, Massachusetts);  Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) John M. Bent (Los Alamos, New Mexico);  Sorin Faibish (Newton, Massachusetts);  Gary Grider (Los Alamos, New Mexico)
ABSTRACT Techniques are provided for parallel compression of data chunks being written to a shared object. A client executing on a compute node or a burst buffer node in a parallel computing system stores a data chunk generated by the parallel computing system to a shared data object on a storage node by compressing the data chunk; and providing the data compressed data chunk to the storage node that stores the shared object. The client and storage node may employ Log-Structured File techniques. The compressed data chunk can be de-compressed by the client when the data chunk is read. A storage node stores a data chunk as part of a shared object by receiving a compressed version of the data chunk from a compute node; and storing the compressed version of the data chunk to the shared data object on the storage node.
FILED Wednesday, March 13, 2013
APPL NO 13/799228
ART UNIT 2451 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 3/067 (20130101)
G06F 17/30224 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/42 (20130101)
H04L 67/1097 (20130101)
H04L 69/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477901 Paiton et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Dylan M. Paiton (Rio Rancho, New Mexico);  Garrett T. Kenyon (Santa Fe, New Mexico);  Steven P. Brumby (Santa Fe, New Mexico);  Peter F. Schultz (Los Alamos, New Mexico);  John S. George (White Rock, New Mexico)
ABSTRACT An approach to detecting objects in an image dataset may combine texture/color detection, shape/contour detection, and/or motion detection using sparse, generative, hierarchical models with lateral and top-down connections. A first independent representation of objects in an image dataset may be produced using a color/texture detection algorithm. A second independent representation of objects in the image dataset may be produced using a shape/contour detection algorithm. A third independent representation of objects in the image dataset may be produced using a motion detection algorithm. The first, second, and third independent representations may then be combined into a single coherent output using a combinatorial algorithm.
FILED Wednesday, July 22, 2015
APPL NO 14/805540
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/629 (20130101)
G06K 9/4604 (20130101) Original (OR) Class
G06K 9/4619 (20130101)
G06K 9/4652 (20130101)

Image Data Processing or Generation, in General
G06T 7/20 (20130101)
G06T 7/40 (20130101)
G06T 7/0051 (20130101)
G06T 7/0079 (20130101)
G06T 2207/10024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478782 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Zhengcheng Zhang (Naperville, Illinois);  Khalil Amine (Oak Brook, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Zhengcheng Zhang (Naperville, Illinois);  Khalil Amine (Oak Brook, Illinois)
ABSTRACT A lithium-air battery includes a lithium anode; an air cathode; and a separator between the lithium anode and an air cathode the separator including a cross-linked polysiloxane.
FILED Friday, September 07, 2012
APPL NO 13/606290
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 77/12 (20130101)
C08G 77/14 (20130101)
C08G 77/38 (20130101)
C08G 77/46 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 183/12 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/145 (20130101)
H01M 2/1653 (20130101)
H01M 2/1673 (20130101) Original (OR) Class
H01M 2/1686 (20130101)
H01M 4/98 (20130101)
H01M 4/8605 (20130101)
H01M 12/08 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 156/10 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478794 Wu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Huiming Wu (Darien, Illinois);  Khalil Amine (Oakbrook, Illinois);  Ali Abouimrane (Aurora, Illinois)
ABSTRACT A secondary battery including a cathode having a primary cathode active material and an alkaline source material selected from the group consisting of Li2O, Li2O2, Li2S, LiF, LiCl, Li2Br, Na2O, Na2O2, Na2S, NaF, NaCl, and a mixture of any two or more thereof; an anode having an anode active material; an electrolyte; and a separator.
FILED Monday, April 20, 2015
APPL NO 14/690641
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101) Original (OR) Class
H01M 4/134 (20130101)
H01M 4/364 (20130101)
H01M 4/382 (20130101)
H01M 4/386 (20130101)
H01M 4/387 (20130101)
H01M 4/485 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/623 (20130101)
H01M 4/625 (20130101)
H01M 4/8668 (20130101)
H01M 4/8673 (20130101)
H01M 4/9016 (20130101)
H01M 4/9041 (20130101)
H01M 8/10 (20130101)
H01M 8/22 (20130101)
H01M 10/052 (20130101)
H01M 10/054 (20130101)
H01M 10/0525 (20130101)
H01M 10/0569 (20130101)
H01M 12/08 (20130101)
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)
H01M 2004/8684 (20130101)
H01M 2004/8689 (20130101)
H01M 2220/10 (20130101)
H01M 2220/20 (20130101)
H01M 2220/30 (20130101)
H01M 2250/10 (20130101)
H01M 2250/20 (20130101)
H01M 2250/30 (20130101)
H01M 2300/0037 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 90/14 (20130101)
Y02B 90/18 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
Y02T 90/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478798 Lu et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sharp Laboratories of America, Inc. (Camas, Washington)
ASSIGNEE(S) Sharp Laboratories of America, Inc. (Camas, Washington)
INVENTOR(S) Yuhao Lu (Camas, Washington);  Jie Song (Vancouver, Washington);  Jong-Jan Lee (Camas, Washington)
ABSTRACT A battery is provided with a hexacyanometallate cathode. The battery cathode is made from hexacyanometallate particles overlying a current collector. The hexacyanometallate particles have the chemical formula AXM1MM2N(CN)Z.d[H2O]ZEO.e[H2O]BND, where A is a metal from Groups 1A, 2A, or 3A of the Periodic Table, where M1 and M2 are each a metal with 2+ or 3+ valance positions, where “ZEO” and “BND” indicate zeolitic and bound water, respectively, where d is 0, and e is greater than 0 and less than 8. The anode material may primarily be a material such as hard carbon, soft carbon, oxides, sulfides, nitrides, silicon, metals, or combinations thereof. The electrolyte is non-aqueous. A method is also provided for fabricating hexacyanometallate with no zeolitic water content in response to dehydration annealing at a temperature of greater than 120 degrees C. and less than 200 degrees C.
FILED Thursday, August 20, 2015
APPL NO 14/830838
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Ammonia; Cyanogen; Compounds Thereof
C01C 3/11 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/58 (20130101)
H01M 4/136 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478837 Amine et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Khalil Amine (Oakbrook, Illinois);  Larry A. Curtiss (Downers Grove, Illinois);  Jun Lu (Bolingbrook, Illinois);  Kah Chun Lau (Darien, Illinois);  Zhengcheng Zhang (Naperville, Illinois);  Yang-Kook Sun (Seoul, South Korea)
ABSTRACT A lithium-air battery includes a cathode including a porous active carbon material, a separator, an anode including lithium, and an electrolyte including a lithium salt and polyalkylene glycol ether, where the porous active carbon material is free of a metal-based catalyst.
FILED Friday, February 27, 2015
APPL NO 14/633408
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/162 (20130101)
H01M 2/1626 (20130101)
H01M 4/96 (20130101)
H01M 4/405 (20130101)
H01M 12/08 (20130101) Original (OR) Class
H01M 2300/0025 (20130101)
H01M 2300/0028 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478855 Judd et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Stephen Judd (Los Alamos, New Mexico);  Nicholas Dallmann (Los Alamos, New Mexico);  Jerry Delapp (Los Alamos, New Mexico);  Michael Proicou (Los Alamos, New Mexico);  Daniel Seitz (Los Alamos, New Mexico);  John Michel (Santa Fe, New Mexico);  Donald Enemark (Los Alamos, New Mexico)
ABSTRACT A field unit and ground station may use commercial off-the-shelf (COTS) components and share a common architecture, where differences in functionality are governed by software. The field units and ground stations may be easy to deploy, relatively inexpensive, and be relatively easy to operate. A novel file system may be used where datagrams of a file may be stored across multiple drives and/or devices. The datagrams may be received out of order and reassembled at the receiving device.
FILED Monday, June 22, 2015
APPL NO 14/745996
ART UNIT 2634 — Digital Communications
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 3/02 (20130101) Original (OR) Class

Transmission
H04B 7/155 (20130101)
H04B 7/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479232 Loui et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Hung Loui (Albuquerque, New Mexico);  Billy C. Brock (Albuquerque, New Mexico)
ABSTRACT The various embodiments presented herein relate to beam steering an array antenna by modifying intermediate frequency (IF) waveforms prior to conversion to RF signals. For each channel, a direct digital synthesis (DDS) component can be utilized to generate a waveform or modify amplitude, timing and phase of a waveform relative to another waveform, whereby the generation/modification can be performed prior to the IF input port of a mixer on each channel. A local oscillator (LO) signal can be utilized to commonly drive each of the mixers. After conversion at the RF output port of each of the mixers, each RF signal can be transmitted by a respective antenna element in the antenna array. Initiation of transmission of each RF signal can be performed simultaneously at each antenna. The process can be reversed during receive whereby timing, amplitude, and phase of the received can be modified digitally post ADC conversion.
FILED Thursday, August 13, 2015
APPL NO 14/826153
ART UNIT 2634 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0408 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/2646 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479513 Jenkins et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Chris Jenkins (Albuquerque, New Mexico);  Lyndon G. Pierson (Albuquerque, New Mexico)
ABSTRACT Techniques and mechanism to selectively provide resource access to a functional domain of a platform. In an embodiment, the platform includes both a report domain to monitor the functional domain and a policy domain to identify, based on such monitoring, a transition of the functional domain from a first integrity level to a second integrity level. In response to a change in integrity level, the policy domain may configure the enforcement domain to enforce against the functional domain one or more resource accessibility rules corresponding to the second integrity level. In another embodiment, the policy domain automatically initiates operations in aid of transitioning the platform from the second integrity level to a higher integrity level.
FILED Wednesday, March 18, 2015
APPL NO 14/661174
ART UNIT 2497 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/20 (20130101)
H04L 63/105 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 09474882 Franklin
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Prytime Medical Devices, Inc. (Boerne, Texas)
ASSIGNEE(S) Prytime Medical Devices, Inc. (Borne, Texas)
INVENTOR(S) Curtis Franklin (Denver, Colorado)
ABSTRACT A system for deploying and selectively inflating a balloon at a desired location, without the aid of fluoroscopy is described.
FILED Tuesday, February 26, 2013
APPL NO 13/777667
ART UNIT 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/12109 (20130101)
A61B 17/12136 (20130101)
A61B 2017/22048 (20130101)
A61B 2090/061 (20160201)
A61B 2090/064 (20160201)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/005 (20130101)
A61M 25/0097 (20130101)
A61M 25/1011 (20130101) Original (OR) Class
A61M 25/1018 (20130101)
A61M 2025/0002 (20130101)
A61M 2025/0681 (20130101)
A61M 2025/1047 (20130101)
A61M 2025/1052 (20130101)
A61M 2025/1095 (20130101)
A61M 2025/09175 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474997 Peterson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Army Edgewood Chemical and Biological Command (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Gregory W Peterson (Belcamp, Maryland);  Jared B. DeCoste (Baltimore, Maryland);  Tyler J Demasky (Glen Burnie, Maryland)
ABSTRACT This invention is directed to a porous sorbent comprising a modified metal-organic framework (MOF) having a hierarchical pore structure. The MOF is modified by plasma-enhanced chemical vapor deposition with air, fluorocarbons, or other sources of fluorine. In preferred embodiments the MOFs are zirconium based. The modified MOF, while surprisingly retaining its crystal structure, comprises a mixture of micropores and mesopores and embedded fluorine atoms.
FILED Thursday, March 19, 2015
APPL NO 14/662357
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/04 (20130101) Original (OR) Class
B01D 2253/31 (20130101)
B01D 2253/204 (20130101)
B01D 2253/308 (20130101)
B01D 2257/30 (20130101)
B01D 2257/2025 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101)
B01J 20/28092 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475089 Zabinski
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Jeffrey F. Zabinski (Yellow Springs, Ohio)
ABSTRACT A new method for durably bonding layers of a functional material to surfaces physically and chemically bonds solid layer lubricants and other functional coatings to a substrate surface by first applying a bond layer of a selected substantially binder-free soft material onto the substrate surface by, for example, burnishing, and then applying the functional layer onto the bond layer. Example soft materials for the bond layer include soft oxides such as antimony trioxide and example solid layer lubricants include graphite, molybdenum disulfide and mixtures of such lubricants. The new method is a major improvement over conventional bonding or coating methods. The process is non-vacuum at ambient temperatures and requires no binders, adhesives, curing or baking. Lubricant performance is enhanced by orders of magnitude compared to conventional approaches. The method is inexpensive, environmentally friendly, applicable to almost any substrate material and scalable.
FILED Monday, January 27, 2014
APPL NO 14/164722
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 8/08 (20130101)
B01J 8/10 (20130101)
B01J 8/38 (20130101)

Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/24 (20130101)
B05D 1/36 (20130101)
B05D 5/00 (20130101)
B05D 5/08 (20130101)
B05D 5/12 (20130101)
B05D 5/083 (20130101)
B05D 5/086 (20130101) Original (OR) Class
B05D 7/52 (20130101)
B05D 2401/32 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 9/00 (20130101)
B32B 9/04 (20130101)
B32B 9/041 (20130101)
B32B 15/00 (20130101)
B32B 15/04 (20130101)
B32B 2250/02 (20130101)
B32B 2250/20 (20130101)
B32B 2264/10 (20130101)
B32B 2264/12 (20130101)
B32B 2264/102 (20130101)
B32B 2264/104 (20130101)
B32B 2264/105 (20130101)
B32B 2264/107 (20130101)
B32B 2264/108 (20130101)
B32B 2307/30 (20130101)
B32B 2307/40 (20130101)
B32B 2307/714 (20130101)
B32B 2307/746 (20130101)
B32B 2307/752 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 28/042 (20130101)
C23C 28/044 (20130101)

Lubricating
F16N 15/00 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/30 (20150115)
Y10T 428/12493 (20150115)
Y10T 428/31678 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475263 Rangan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Krishnaswamy Kasthuri Rangan (Fairfax, Virginia);  Tirumalai Srinivas Sudarshan (Vienna, Virginia)
ASSIGNEE(S) MATERIALS MODIFICATION, INC. (Fairfax, Virginia)
INVENTOR(S) Krishnaswamy Kasthuri Rangan (Fairfax, Virginia);  Tirumalai Srinivas Sudarshan (Vienna, Virginia)
ABSTRACT A protective fabric or material includes a base material and at least one inorganic filler selected from the group consisting of a chemical decontamination agent, a biological decontamination agent, an electromagnetic radiation shielding agent, an antimicrobial agent, a self-decontaminating agent, a decontamination catalyst, a carbon dioxide absorbing agent, and a combination thereof.
FILED Tuesday, November 02, 2010
APPL NO 12/926201
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 27/00 (20130101) Original (OR) Class

Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor
G21F 1/00 (20130101)
G21F 3/00 (20130101)
G21F 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475855 Kitajewski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Jan Kitajewski (Ridgewood, New Jersey);  Carrie Shawber (Washington Township, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Jan Kitajewski (Ridgewood, New Jersey);  Carrie Shawber (Washington Township, New Jersey)
ABSTRACT This invention provides a fusion protein comprising a signal peptide, EGF repeats 1-X of the extracellular domain of human Notch3 receptor protein wherein X is any integer from 12 to 34, and an Fc portion of an antibody bound thereto. This invention also provides a method for treating a subject having a tumor, a method for inhibiting angiogenesis in a subject, a method for treating a subject having ovarian cancer, and a method for treating a subject having a metabolic disorder, comprising administering to the subject an amount of the above fusion protein effective to treat the subject. This invention further provides uses of the above fusion protein for the preparation of a pharmaceutical composition for the treatment of a subject having a tumor, for inhibiting angiogenesis in a subject, for treating a subject having ovarian cancer, and for treating a subject having a metabolic disorder.
FILED Friday, August 21, 2009
APPL NO 13/060254
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/177 (20130101)
A61K 38/179 (20130101)
A61K 38/1793 (20130101)
A61K 39/395 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/71 (20130101)
C07K 14/485 (20130101) Original (OR) Class
C07K 14/705 (20130101)
C07K 14/715 (20130101)
C07K 16/46 (20130101)
C07K 2319/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475912 White et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Timothy J. White (Centerville, Ohio);  Kyung Min Lee (Dayton, Ohio)
ABSTRACT This application discloses a method of photomechanically manipulating optically fixable SMPs that employ glassy, photoresponsive polymeric materials, which are capable of rapid optical-fixing with short exposures (<<5 min) of eye-safe visible light. Key to the optical fixing is the use of polymeric materials composed of covalently attached photochromic units such as azobenzene and the use of light capable of inducing simultaneous trans-cis and cis-trans isomerization of azobenzene or other photochromic moieties capable of similar cycling. Upon exposure to light in this wavelength regime (440-514 nm for the azobenzene unit here), real and lasting reconfigurations are induced capable of fixing both the optically induced strain as well as mechanically induced strain. A linear dependence of bending angle on polarization angle is observed and may be used to control the shape reconfiguration of the SMPs.
FILED Monday, August 24, 2015
APPL NO 14/833347
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 7/123 (20130101) Original (OR) Class
C08J 2339/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476065 Horwitz et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Amyris, Inc. (Emeryville, California)
ASSIGNEE(S) AMYRIS, INC. (Emeryville, California)
INVENTOR(S) Andrew Horwitz (Emeryville, California);  Kristy Michelle Hawkins (Emeryville, California);  Max Schubert (Emeryville, California);  Wayne Szeto (Emeryville, California)
ABSTRACT Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. In certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, a nuclease capable of causing a break at the genomic target site, and a linear nucleic acid capable of homologous recombination with itself or with one or more additional linear nucleic acids contacted with the population of cells, whereupon said homologous recombination results in formation of a circular extrachromosomal nucleic acid comprising a coding sequence for a selectable marker. In some embodiments, the methods further comprise selecting a host cell that expresses the selectable marker.
FILED Friday, December 19, 2014
APPL NO 14/577997
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/111 (20130101)
C12N 15/902 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 2310/10 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6897 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476399 Munson
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Scott M. Munson (Monona, Wisconsin)
ASSIGNEE(S) Orbital Technologies Corporation (Madison, Wisconsin)
INVENTOR(S) Scott M. Munson (Monona, Wisconsin)
ABSTRACT An acoustic resonance igniter uses high-pressure helium to heat a resonance cavity so a hot surface of the resonance cavity forms a source of ignition to a combustion chamber. The resonance cavity may be round or may extend linearly to increase the size of the hot surface. The combustion chamber is cooled by arranging a feed of hydrogen and oxygen which is oxygen rich and which becomes more so when ignition occurs. A second combustion chamber receives the combustion chamber output and adds additional hydrogen through ports tangential to the wall of the second combustion chamber to enrich the fuel ratio and cool the second combustion chamber. The acoustic resonance igniter is used to ignite a large rocket engine or to form a rocket thruster.
FILED Wednesday, May 15, 2013
APPL NO 13/894919
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines
F02P 23/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476429 Beach
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Brian Beach (East Hartford, Connecticut)
ABSTRACT A feed diffuser is disclosed. The diffuser may comprise a base disposed orthogonal to a flow, a body extending from the base toward the flow, and an apex provided at a termination of the body in a direction toward the flow. The body may decrease in cross-sectional area from the base to the apex.
FILED Wednesday, December 19, 2012
APPL NO 13/719748
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 25/12 (20130101)

Non-positive-displacement Pumps
F04D 29/002 (20130101) Original (OR) Class

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/04 (20130101)
F23R 2900/03044 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476700 DeWeert et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Michael J. DeWeert (Kailua, Hawaii);  Andrew N. Acker (Honolulu, Hawaii)
ABSTRACT A shearography system and method provide advances allowing for rapid processing to produce shearograms which provide surface motion information which may be helpful in multiple fields. For instance, amongst virtually endless possibilities, the system and method may allow for detection of underground structures or ordnance and or be used in the medical field to provide non-contact sensing of a person's internal structures or movements.
FILED Tuesday, November 11, 2014
APPL NO 14/538444
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/162 (20130101) Original (OR) Class

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 17/88 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/226 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476730 Samarasekera et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI INTERNATIONAL (Menlo Park, California)
INVENTOR(S) Supun Samarasekera (Princeton, New Jersey);  Raia Hadsell (Princeton Junction, New Jersey);  Rakesh Kumar (West Windsor, New Jersey);  Harpreet S. Sawhney (Princeton Junction, New Jersey);  Bogdan C. Matei (Princeton Junction, New Jersey);  Ryan Villamil (Plainsboro, New Jersey)
ABSTRACT A multi-sensor, multi-modal data collection, analysis, recognition, and visualization platform can be embodied in a navigation capable vehicle. The platform provides an automated tool that can integrate multi-modal sensor data including two-dimensional image data, three-dimensional image data, and motion, location, or orientation data, and create a visual representation of the integrated sensor data, in a live operational environment. An illustrative platform architecture incorporates modular domain-specific business analytics “plug ins” to provide real-time annotation of the visual representation with domain-specific markups.
FILED Thursday, December 18, 2014
APPL NO 14/575495
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 11/02 (20130101)
G01C 21/32 (20130101)
G01C 21/3673 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00637 (20130101)
G06K 9/6267 (20130101)
G06K 9/6293 (20130101)

Image Data Processing or Generation, in General
G06T 17/05 (20130101)
G06T 2200/04 (20130101)
G06T 2207/10012 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476769 Islam
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) OMNI MEDSCI, INC. (Ann Arbor, Michigan)
ASSIGNEE(S) Omni Medsci, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Mohammed N. Islam (Ann Arbor, Michigan)
ABSTRACT An optical system includes a tunable semiconductor light emitter that generates an input beam having a wavelength shorter than about 2.5 microns, an optical isolator coupled to the emitter and configured to block reflected light into the emitter, an optical amplifier receiving the input beam and outputting an intermediate beam, and optical fibers receiving the intermediate beam and forming an output beam. A subsystem includes lenses or mirrors that deliver the output beam to a sample. The subsystem may include an Optical Coherence Tomography (OCT) apparatus having a sample arm and a reference arm, the output beam having a temporal duration greater than approximately 30 picoseconds, a repetition rate between continuous wave and Megahertz or higher, and a time averaged intensity less than approximately 50 MW/cm2. The system may also include a light detection system collecting any of the output beam that reflects or transmits from the sample.
FILED Tuesday, September 22, 2015
APPL NO 14/861755
ART UNIT 2874 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02091 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101) Original (OR) Class
G01J 3/108 (20130101)
G01J 3/0218 (20130101)
G01J 3/0245 (20130101)
G01J 2003/102 (20130101)
G01J 2003/423 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/29349 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 2001/3528 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/302 (20130101)
H01S 3/1024 (20130101)
H01S 3/06725 (20130101)
H01S 3/06754 (20130101)
H01S 3/094069 (20130101)
H01S 3/094076 (20130101)
H01S 5/0064 (20130101)
H01S 5/0085 (20130101)
H01S 5/146 (20130101)
H01S 5/1092 (20130101)
H01S 2301/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476818 Martin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Chadwick B. Martin (Tucson, Arizona);  Rex M. Kremer (Tucson, Arizona);  Jesse C. Temkin (Tucson, Arizona)
ABSTRACT A detector assembly includes a dewar chamber having an aperture and an infrared radiation detector. The detector assembly also includes a mirror disposed adjacent the aperture of the dewar chamber, where the mirror has a reflective surface and an emitting region facing the aperture. The infrared radiation detector is configured to detect first radiation and second radiation from the mirror. The first radiation originates from at least one relatively cold surface in the dewar chamber and reflects off the reflective surface of the mirror. The second warm radiation originates from at least one relatively warm surface at or behind the emitting region. The infrared radiation detector is also configured to detect an artifact caused by a particle in the dewar chamber that blocks a portion of the first or second radiation.
FILED Wednesday, September 23, 2015
APPL NO 14/863016
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1434 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476830 Pantazis et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Periklis Pantazis (Pasadena, California);  Ye Pu (Pasadena, California);  Demetri Psaltis (St-Sulpice, Switzerland);  John H. Hong (Pasadena, California);  Scott E. Fraser (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Periklis Pantazis (Pasadena, California);  Ye Pu (Pasadena, California);  Demetri Psaltis (St-Sulpice, Switzerland);  John H. Hong (Pasadena, California);  Scott E. Fraser (Pasadena, California)
ABSTRACT Second harmonic nanoprobes for imaging biological samples and a method of using such probes to monitor the dynamics of biological process using a field resonance enhanced second harmonic (FRESH) technique are provided. The second harmonic generating (SHG) nanoprobes are comprised of various kinds of nanocrystals that do not possess an inversion symmetry and therefore are capable of generating second harmonic signals that can then be detected by conventional two-photon microscopy for in vivo imaging of biological processes and structures such as cell signaling, neuroimaging, protein conformation probing, DNA conformation probing, gene transcription, virus infection and replication in cells, protein dynamics, tumor imaging and cancer therapy evaluation and diagnosis as well as quantification in optical imaging.
FILED Wednesday, November 21, 2007
APPL NO 11/944264
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 20/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/636 (20130101) Original (OR) Class

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/37 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476862 Motayed et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland);  The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia);  George Mason University (Fairfax, Virginia);  The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  The United States of America, as Represented by the Secretary of Commerce, National Institute of Standards and Technology (Washington, District of Columbia);  George Mason University (Fairfax, Virginia);  The George Washington University (Washington, District of Columbia)
INVENTOR(S) Abhishek Motayed (Rockville, Maryland);  Geetha Aluri (Clifton Park, New York);  Albert V. Davydov (North Potomac, Maryland);  Mulpuri V. Rao (Fairfax Station, Virginia);  Vladimir P. Oleshko (Gaithersburg, Maryland);  Ritu Bajpai (Santa Clara, California);  Mona E. Zaghloul (Bethesda, Maryland)
ABSTRACT A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte.
FILED Friday, April 12, 2013
APPL NO 13/861962
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3278 (20130101)
G01N 27/4146 (20130101)
G01N 33/0031 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476973 Mazzaro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Gregory J Mazzaro (Charleston, South Carolina);  Kelly D. Sherbondy (Burke, Virginia);  DaHan Liao (Bethesda, Maryland)
ABSTRACT A radar assembly for linear and nonlinear radar transmission and reception comprising a signal generator; at least one filter operatively connected to the signal generator; a transmitter operatively connected to the at least one filter for transmitting radar signals; a receiver operative to receiving received signals comprising linear and nonlinear responses from the reflected transmitted signals; the receiver comprising a first channel for processing the linear response of the received signal; a second channel for the processing the nonlinear response of the received signal; at least one switch operative to select one of the first or second channels; at least one high pass filter operatively connected to the second channel to attenuate the linear response; at least one amplifier to amplify the nonlinear response; and at least one display operatively connected to both the first and second channels for displaying both linear and nonlinear responses.
FILED Friday, September 20, 2013
APPL NO 14/032387
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/04 (20130101) Original (OR) Class
G01S 13/87 (20130101)
G01S 13/106 (20130101)
G01S 13/343 (20130101)
G01S 13/885 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477307 Chizeck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
APPLICANT(S) University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) The University of Washington (Seattle, Washington)
INVENTOR(S) Howard Jay Chizeck (Mercer Island, Washington);  Fredrik Ryden (Seattle, Washington)
ABSTRACT Methods, articles of manufacture, and devices related to generating six degree of freedom (DOF) haptic feedback are provided. A computing device can receive first depth data about an environment. The computing device can generate a first plurality of points from the first depth data. The computing device can determine a virtual tool, where the virtual tool is specified in terms of a translation component for the virtual tool and a rotation component for the virtual tool. The computing device can determine a first force vector between the virtual tool and the first plurality of points. The computing device can send a first indication of haptic feedback based on the first force vector.
FILED Friday, January 24, 2014
APPL NO 14/164114
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/25 (20160201)

Electric Digital Data Processing
G06F 3/016 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 15/04 (20130101)

Pictorial Communication, e.g Television
H04N 5/2256 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477526 Johnson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Energy (DOE)
APPLICANT(S) NVIDIA Corporation (Santa Clara, California)
ASSIGNEE(S) NVIDIA Corporation (Santa Clara, California)
INVENTOR(S) Daniel Robert Johnson (Austin, Texas);  Minsoo Rhu (Austin, Texas);  James M. O'Connor (Austin, Texas);  Stephen William Keckler (Austin, Texas)
ABSTRACT A system, method, and computer program product are provided for providing prioritized access for multithreaded processing. The method includes the steps of allocating threads to process a workload and assigning a set of priority tokens to at least a portion of the threads. Access to a resource, by each one of the threads, is based on the priority token assigned to the thread and the threads are executed by a multithreaded processor to process the workload.
FILED Friday, January 03, 2014
APPL NO 14/147395
ART UNIT 2195 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/48 (20130101)
G06F 9/5016 (20130101)
G06F 9/5027 (20130101) Original (OR) Class
G06F 2209/5021 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 60/142 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477568 Allen-Ware et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Malcolm S. Allen-Ware (Austin, Texas);  Jon A. Casey (Pooghkeepsie, New York);  Sungjun Chun (Austin, Texas);  Alan J. Drake (Round Rock, Texas);  Charles R. Lefurgy (Austin, Texas);  Karthick Rajamani (Austin, Texas);  Jeonghee Shin (Millwood, New York);  Thomas A. Wassick (LaGrangeville, New York);  Victor Zyuban (Yorktown Heights, New York)
ABSTRACT A mechanism is provided for determining a modeled age of a set of interconnect groups in a set of cores in a set of multi-core processors. For each interconnect group in the set of interconnect groups in the set of cores on the set of multi-core processors, a determination is made of a current modeled age of the interconnect group. A determination is then made as to whether at least one current modeled age of the interconnect group for the set of interconnect groups is greater than an end-of-life value. Responsive to at least one current modeled age of the interconnect group being greater than the end-of-life value, an indication to take corrective action with the at least one associated interconnect group is sent.
FILED Friday, September 27, 2013
APPL NO 14/039047
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 11/004 (20130101)
G06F 11/0703 (20130101)
G06F 11/3006 (20130101) Original (OR) Class
G06F 11/3027 (20130101)
G06F 11/3058 (20130101)
G06F 11/3093 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477753 Kingsbury et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Brian E. D. Kingsbury (Cortlandt Manor, New York);  Hong-Kwang Jeff Kuo (Pleasantville, New York);  Lidia Luminita Mangu (New York, New York);  Hagen Soltau (Yorktown Heights, New York)
ABSTRACT Systems and methods for processing a query include determining a plurality of sets of match candidates for a query using a processor, each of the plurality of sets of match candidates being independently determined from a plurality of diverse word lattice generation components of different type. The plurality of sets of match candidates is merged by generating a first score for each match candidate to provide a merged set of match candidates. A second score is computed for each match candidate of the merged set based upon features of that match candidate. The first score and the second score are combined to provide a final set of match candidates as matches to the query.
FILED Tuesday, March 12, 2013
APPL NO 13/796670
ART UNIT 2675 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Electric Digital Data Processing
G06F 17/3074 (20130101) Original (OR) Class

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 15/02 (20130101)
G10L 15/32 (20130101)
G10L 15/083 (20130101)
G10L 15/265 (20130101)
G10L 15/1822 (20130101)
G10L 25/54 (20130101)
G10L 2015/088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477796 Garcia-Ramirez et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Hector J. Garcia-Ramirez (Ypsilanti, Michigan);  Igor L. Markov (Ann Arbor, Michigan)
ABSTRACT The disclosed method and computer-readable medium allow efficient simulation of both stabilizer and non-stabilizer states in general quantum circuits on a classical computer by maintaining global phases and orthogonalizing linear combinations of stabilizer states during simulation. This is accomplished by representing arbitrary quantum states as superpositions of stabilizer states, which may be implemented using one or more stabilizer frames. Each stabilizer frame includes a stabilizer matrix, one or more phase vectors corresponding to the stabilizer states, and an amplitude vector corresponding to the global phases of each stabilizer state. Orthogonality is maintained throughout the simulation for efficient computation and measurement. Some embodiments utilize a multiframe representation of the quantum state to reduce the number of stabilizer states required to represent the quantum state, which multiframe representation may also be used to implement parallel simulation.
FILED Friday, May 22, 2015
APPL NO 14/719884
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Electric Digital Data Processing
G06F 17/16 (20130101)
G06F 17/5009 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 99/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477909 Fishel et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) SYNTOUCH, LLC (Los Angeles, California)
ASSIGNEE(S) SYNTOUCH, LLC (Los Angeles, California)
INVENTOR(S) Jeremy A. Fishel (Fullerton, California);  Gerald E. Loeb (South Pasadena, California)
ABSTRACT An object investigation and classification system may include an object test system, a data storage system, and a data processing system. The object test system may receive a command to perform at least one action with a test object, perform the at least one action with the test object, and return test information indicative of at least one percept resulting from the at least one action. The data storage system may contain an experience database containing data indicative of multiple classifications and, for each classification, at least one action that was performed with at least one previously-observed reference object having this classification, and at least one percept value that is based in whole or in part on the test information resulting from the at least one action.
FILED Thursday, January 09, 2014
APPL NO 14/151625
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 21/30 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6277 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477999 Hameed et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Rehan Hameed (Palo Alto, California);  Wajahat Qadeer (Menlo Park, California);  Christoforos Kozyrakis (Stanford, California);  Mark A. Horowitz (Stanford, California)
ABSTRACT A convolution image processor includes a load and store unit, a shift register unit, and a mapping unit. The load and store unit is configured to load and store image pixel data and allow for unaligned access of the image pixel data. The shift register is configured to load and store at least a portion of the image pixel data from the load and store unit and concurrently provide access to each image pixel value in the portion of the image pixel data. The mapping unit is configured to generate a number of shifted versions of image pixel data and corresponding stencil data from the portion of the image pixel data, and concurrently perform one or more operations on each image pixel value in the shifted versions of the portion of the image pixel data and a corresponding stencil value in the corresponding stencil data.
FILED Monday, September 22, 2014
APPL NO 14/492535
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 1/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478034 Rosenwinkel
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Lockheed Martin Corporation (Bethesda, Maryland)
ASSIGNEE(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
INVENTOR(S) Alan M. Rosenwinkel (Haddonfield, New Jersey)
ABSTRACT A system and method are disclosed for determining geoposition of an observer. The system includes a sensor such as a wide field of view camera or telescope that can capture an image of the sky. The image of the sky is used to compile a table or list of the stars in the sky along with their positions. This table or list is pattern-matched with a predetermined list or table of stars to identify each star. In one embodiment, the distances between all stars in the image are computed and compared to star images from an atmospheric refraction model. A comparison of the measured table or list and the refraction model, using an optimization algorithm, is performed to determine the geoposition of the observer. In an alternative embodiment, a sensor capable of measuring two different frequency bands obtains two images of each star in the sky simultaneously. A difference in displacement is determined between the two frequencies for each imaged star; and a magnitude and direction of the difference in displacement is used to determine the geoposition of a body.
FILED Tuesday, July 01, 2014
APPL NO 14/321375
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101)
G06K 9/6202 (20130101)

Image Data Processing or Generation, in General
G06T 7/0044 (20130101) Original (OR) Class
G06T 2207/30212 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478229 Lacirignola et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Joseph J. Lacirignola (Beverly, Massachusetts);  Trina Rae Vian (Westford, Massachusetts);  David F. Aubin, Jr. (Pelham, New Hampshire);  Thomas F. Quatieri (Newtonville, Massachusetts);  Kate D. Fischl (Cambridge, Massachusetts);  Paula P. Collins (Arlington, Massachusetts);  Christopher J. Smalt (Arlington, Massachusetts);  Paul D. Gatewood (Medford, Massachusetts);  Nicolas Malyska (Watertown, Massachusetts);  David C. Maurer (Stoneham, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Joseph J. Lacirignola (Beverly, Massachusetts);  Trina Rae Vian (Westford, Massachusetts);  David F. Aubin, Jr. (Pelham, New Hampshire);  Thomas F. Quatieri (Newtonville, Massachusetts);  Kate D. Fischl (Cambridge, Massachusetts);  Paula P. Collins (Arlington, Massachusetts);  Christopher J. Smalt (Arlington, Massachusetts);  Paul D. Gatewood (Medford, Massachusetts);  Nicolas Malyska (Watertown, Massachusetts);  David C. Maurer (Stoneham, Massachusetts)
ABSTRACT Loud sounds with fast rise times, like gunfire and explosions, can cause noise-induced hearing loss (NIHL). Unfortunately, current models do not adequately explain how impulsive sounds cause NIHL, which makes it difficult to predict and prevent NIHL on battlefields and other hostile or rugged environments. Fortunately, the impulsive sounds experienced by soldiers and others working in rugged environments can be recorded using a compact, portable system that acquires, digitizes, and stores high-bandwidth audio data. An example of this system can be mounted on a helmet or other article and used to record hours of audio data at a bandwidth of 20 kHz or higher, which is broad enough to capture sounds with rise times less than 50 ms. An analog-to-digital converter (ADC) digitizes these broadband audio signals at rate of 40 kHz or higher to preserve the impulse information. A processor transfers the digitized samples from a buffer to a memory card for later retrieval using an interrupt-driven processing technique.
FILED Tuesday, December 10, 2013
APPL NO 14/101802
ART UNIT 2651 — Videophones and Telephonic Communications
CURRENT CPC
Electric Digital Data Processing
G06F 3/165 (20130101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 21/0208 (20130101) Original (OR) Class

Information Storage Based on Relative Movement Between Record Carrier and Transducer
G11B 20/10 (20130101)
G11B 20/24 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 3/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478403 Lozano et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Paulo C. Lozano (Arlington, Massachusetts);  Steven Mark Arestie (Redondo Beach, California)
ABSTRACT An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or room-temperature molten salt. The body can have a pore size gradient that decreases from the base of the body to the tip of the body, such that the at least one of an ionic liquid or room-temperature molten salt is capable of being transported through capillarity from the base to the tip.
FILED Monday, July 21, 2014
APPL NO 14/336814
ART UNIT 2881 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/14 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 1/05 (20130101)
H01J 9/02 (20130101)
H01J 37/08 (20130101)
H01J 49/0445 (20130101) Original (OR) Class
H01J 2237/0802 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478429 Ghariehali et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Amir Tavakkoli Kermani Ghariehali (Tehran, Iran);  Samuel Mospens Nicaise (Cambridge, Massachusetts);  Karl K. Berggren (Arlington, Massachusetts);  Kevin Willy Gotrik (Cambridge, Massachusetts);  Caroline A. Ross (Arlington, Massachusetts)
ABSTRACT A sacrificial-post templating method is presented for directing block copolymer (BCP) self-assembly to form nanostructures of monolayers and bilayers of microdomains. The topographical post template can be removed after directing self-assembly and, therefore, is not incorporated into the final microdomain pattern. The sacrificial posts can be a material removable using a selective etchant that will not remove the material of the final pattern block(s). The sacrificial posts may be removable, at least in part, using a same etchant as for removing one of the blocks of the BCP, for example, a negative tone polymethylmethacrylate (PMMA) when a non-final pattern block of polystyrene is removed and polydimethylsiloxane (PDMS) remains on the substrate.
FILED Wednesday, March 13, 2013
APPL NO 13/800435
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00031 (20130101)
B81C 1/00111 (20130101)
B81C 1/00428 (20130101)
B81C 2201/0149 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0002 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0271 (20130101)
H01L 21/3081 (20130101) Original (OR) Class
H01L 21/31058 (20130101)
H01L 21/31138 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478458 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S) Chunbo Zhang (Manhattan Beach, California);  Peter Ngo (Crpress, California);  Gershon Akerling (Culver City, California);  Kevin M. Leong (Los Angeles, California);  Patty Chang-Chien (Redondo Beach, California);  Kelly J. Hennig (Torrance, California);  William R. Deal (Redondo Beach, California)
ABSTRACT A method and apparatus for integrating individual III-V MMICs into a micromachined waveguide package is disclosed. MMICs are screened prior to integration, allowing only known-good die to be integrated, leading to increased yield. The method and apparatus are used to implement a micro-integrated Focal Plane Array (mFPA) technology used for sub millimeter wave (SMMW) cameras, although many other applications are possible. MMICs of different technologies may be integrated into the same micromachined package thus achieving the same level of technology integration as in multi-wafer WLP integration.
FILED Wednesday, January 08, 2014
APPL NO 14/149965
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/76254 (20130101) Original (OR) Class
H01L 23/055 (20130101)
H01L 23/66 (20130101)
H01L 23/147 (20130101)
H01L 24/13 (20130101)
H01L 24/16 (20130101)
H01L 24/81 (20130101)
H01L 24/97 (20130101)
H01L 2223/6633 (20130101)
H01L 2223/6677 (20130101)
H01L 2223/6683 (20130101)
H01L 2224/03 (20130101)
H01L 2224/81 (20130101)
H01L 2224/94 (20130101)
H01L 2224/94 (20130101)
H01L 2224/97 (20130101)
H01L 2224/97 (20130101)
H01L 2224/0401 (20130101)
H01L 2224/13109 (20130101)
H01L 2224/13109 (20130101)
H01L 2224/16225 (20130101)
H01L 2224/16235 (20130101)
H01L 2224/81022 (20130101)
H01L 2224/81054 (20130101)
H01L 2224/81191 (20130101)
H01L 2224/81192 (20130101)
H01L 2224/81204 (20130101)
H01L 2224/81805 (20130101)
H01L 2224/81815 (20130101)
H01L 2924/00 (20130101)
H01L 2924/157 (20130101)
H01L 2924/01079 (20130101)
H01L 2924/1423 (20130101)
H01L 2924/10329 (20130101)
H01L 2924/10335 (20130101)
H01L 2924/12032 (20130101)
H01L 2924/12032 (20130101)
H01L 2924/13064 (20130101)
H01L 2924/14215 (20130101)
H01L 2924/15313 (20130101)
H01L 2924/37001 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 11/002 (20130101)

Antennas, i.e Radio Aerials
H01Q 13/02 (20130101)
H01Q 23/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478537 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Qingchun Zhang (Cary, North Carolina);  Anant K. Agarwal (Chapel Hill, North Carolina)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Qingchun Zhang (Cary, North Carolina);  Anant K. Agarwal (Chapel Hill, North Carolina)
ABSTRACT A packaged power electronic device includes a wide bandgap bipolar driver transistor having a base, a collector, and an emitter terminal, and a wide bandgap bipolar output transistor having a base, a collector, and an emitter terminal. The collector terminal of the output transistor is coupled to the collector terminal of the driver transistor, and the base terminal of the output transistor is coupled to the emitter terminal of the driver transistor to provide a Darlington pair. An area of the output transistor is at least 3 times greater than an area of the driver transistor in plan view. For example, an area ratio of the output transistor to the driver transistor may be between about 3:1 to about 5:1. Related devices and methods of fabrication are also discussed.
FILED Wednesday, July 15, 2009
APPL NO 12/503386
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/8213 (20130101)
H01L 27/0825 (20130101) Original (OR) Class
H01L 29/73 (20130101)
H01L 29/1608 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478616 Dhar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Sarit Dhar (Cary, North Carolina);  Sei-Hyung Ryu (Cary, North Carolina);  Lin Cheng (Chapel Hill, North Carolina);  Anant Agarwal (Chapel Hill, North Carolina)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Sarit Dhar (Cary, North Carolina);  Sei-Hyung Ryu (Cary, North Carolina);  Lin Cheng (Chapel Hill, North Carolina);  Anant Agarwal (Chapel Hill, North Carolina)
ABSTRACT Semiconductor devices having a high performance channel and method of fabrication thereof are disclosed. Preferably, the semiconductor devices are Metal-Oxide-Semiconductor (MOS) devices, and even more preferably the semiconductor devices are Silicon Carbide (SiC) MOS devices. In one embodiment, a semiconductor device includes a SiC substrate of a first conductivity type, a first well of a second conductivity type, a second well of the second conductivity type, and a surface diffused channel of the second conductivity type formed at the surface of semiconductor device between the first and second wells. A depth and doping concentration of the surface diffused channel are controlled to provide increased carrier mobility for the semiconductor device as compared to the same semiconductor device without the surface diffused channel region when in the on-state while retaining a turn-on, or threshold, voltage that provides normally-off behavior.
FILED Thursday, March 03, 2011
APPL NO 13/039441
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/225 (20130101)
H01L 29/107 (20130101) Original (OR) Class
H01L 29/1608 (20130101)
H01L 29/66068 (20130101)
H01L 29/66477 (20130101)
H01L 29/66568 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478699 Myers et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Roberto C. Myers (Columbus, Ohio);  Siddharth Rajan (Columbus, Ohio)
ASSIGNEE(S) THE OHIO STATE UNIVERSITY (Columbus, Ohio)
INVENTOR(S) Roberto C. Myers (Columbus, Ohio);  Siddharth Rajan (Columbus, Ohio)
ABSTRACT A nanowire comprises a polar semiconductor material that is compositionally graded along the nanowire from a first end to a second end to define a polarization doping profile along the nanowire from the first end to the second end. The polar semiconductor material may comprise a group IH-nitride semiconductor, such as an alloy of GaN and AlN, or an alloy of GaN and InN. Such nanowires may be formed by nucleating the first ends on a substrate, growing the nanowires by depositing polar semiconductor material on the nucleated first ends on a selected growth face, and compositionally grading the nanowires during growth to impart the polarization doping. The direction of the compositional grading may be reversed during the growing of the nanowires to reverse the type of the imparted polarization doping. In some embodiments, the reversing forms n/p or p/n junctions in the nanowires.
FILED Thursday, August 25, 2011
APPL NO 13/819006
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 20/00 (20130101)
B82Y 30/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0251 (20130101)
H01L 21/0254 (20130101)
H01L 21/02458 (20130101)
H01L 21/02573 (20130101)
H01L 21/02603 (20130101)
H01L 21/02636 (20130101)
H01L 29/15 (20130101)
H01L 29/068 (20130101)
H01L 29/122 (20130101)
H01L 29/205 (20130101)
H01L 29/0673 (20130101)
H01L 29/0676 (20130101)
H01L 29/775 (20130101)
H01L 29/861 (20130101)
H01L 29/2003 (20130101)
H01L 29/66469 (20130101)
H01L 31/065 (20130101)
H01L 31/109 (20130101)
H01L 31/1848 (20130101)
H01L 31/1852 (20130101)
H01L 31/03529 (20130101)
H01L 31/035227 (20130101)
H01L 33/04 (20130101) Original (OR) Class
H01L 33/08 (20130101)
H01L 33/18 (20130101)
H01L 33/32 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478730 Chepulskyy et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) SAMSUNG ELECTRONICS CO., LTD. (Gyeonggi-do, South Korea)
ASSIGNEE(S) SAMSUNG ELECTRONICS CO., LTD. (Gyeonggi-Do, South Korea)
INVENTOR(S) Roman Chepulskyy (Milpitas, California);  Dmytro Apalkov (San Jose, California);  Alexey Vasilyevitch Khvalkovskiy (Milpitas, California)
ABSTRACT A method and system for providing a magnetic junction usable in a magnetic device are described. The magnetic junction includes a pinned layer, a nonmagnetic spacer layer, and a free layer. The nonmagnetic spacer layer is between the pinned layer and the free layer. The magnetic junction is configured such that the free layer is switchable between a plurality of stable magnetic states when a write current is passed through the magnetic junction. At least one of the pinned layer and the free layer includes a magnetic substructure. The magnetic substructure includes at least two magnetic layers interleaved with at least one insertion layer. Each of the at least one insertion layer includes at least one of Bi, W, I, Zn, Nb, Ag, Cd, Hf, Os, Mo, Ca, Hg, Sc, Y, Sr, Mg, Ti, Ba, K, Na, Rb, Pb, and Zr. The at least two magnetic layers are magnetically coupled.
FILED Thursday, April 18, 2013
APPL NO 13/865445
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 43/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478936 Ushinsky
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Michael Ushinsky (Irvine, California)
ABSTRACT A method for preparing a surface of a YAG crystal for thermal bonding includes performing an ion implantation process to introduce nitrogen into a surface layer of the YAG crystal to replace depleted oxygen therein, to change surface energy of the surface layer of the YAG crystal and to provide desired bonding characteristics for the surface layer; and joining the ion implanted surface layer with a thermal management device configured to dissipate heat from the YAG crystal. Also, a micro-chip device having a YAG crystal whose surface is prepared with the above disclosed method is provided and a device for forming a metallization pattern on a surface of the YAG crystal is provided.
FILED Thursday, May 09, 2013
APPL NO 13/890970
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Apparatus for Applying Fluent Materials to Surfaces, in General
B05C 13/02 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/04 (20130101)
C23C 16/04 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 29/28 (20130101)
C30B 31/22 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/042 (20130101)
H01S 3/0621 (20130101)
H01S 3/0627 (20130101)
H01S 3/1643 (20130101)
H01S 3/1666 (20130101)
H01S 5/024 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 156/10 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479105 Rozman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
INVENTOR(S) Gregory I. Rozman (Rockford, Illinois);  Francis A. Carcia (Enfield, Connecticut);  Gabriel Ackerman (Manchester, Connecticut)
ABSTRACT A poly-phase motor drive includes an input EMI filter having a poly-phase filter input and a poly-phase filter output and an active rectifier connected to the filter output. The input EMI filter includes notch filters tuned at active rectifier and motor drive inverter switching frequencies and diverts common-mode current into DC bus. The active rectifier has a DC output. A motor drive inverter is connected to the DC output. The motor drive inverter has a poly-phase motor control output.
FILED Friday, February 07, 2014
APPL NO 14/175121
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 19/2509 (20130101)
G01R 19/2513 (20130101)
G01R 31/007 (20130101)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/12 (20130101)
H02M 1/44 (20130101)
H02M 2001/123 (20130101)

Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 29/0038 (20130101) Original (OR) Class

Transmission
H04B 3/28 (20130101)
H04B 3/30 (20130101)
H04B 2203/5475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479185 Cali et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Joseph D. Cali (Nashua, New Hampshire);  Steven E. Turner (Nashua, New Hampshire)
ABSTRACT A phase coherent fractional-N phase-locked loop synthesizer for maintaining phase coherence of a synthesized frequency includes a phase coherent delta-sigma modulator (DSM) having a plurality of feed-forward accumulator stages. The DSM is operatively coupled to a reference clock configured to generate a cyclical reference signal. The DSM configured to count a number of cycles of the reference signal, to cause, at each cycle of the reference signal, each of the stages of the DSM to accumulate a sum of a previous stage of the DSM, and to multiply each sum by a fractional divide word to produce a multiplier output, thereby causing the DSM to output a sequence of signals that tracks with the reference clock.
FILED Monday, December 14, 2015
APPL NO 14/968180
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/1806 (20130101) Original (OR) Class

Coding; Decoding; Code Conversion in General
H03M 7/3033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 09474271 John et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute on Aging (NIA)
National Science Foundation (NSF)
APPLICANT(S) Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York);  The Curators of The University of Missouri (Columbia, Missouri);  University of North Texas (Denton, Texas)
INVENTOR(S) George John (New York, New York);  Subbiah Nagarajan (New York, New York);  Kent Chapman (Denton, Texas);  Lionel Faure (Flower Mound, Texas);  Peter Koulen (Leawood, Kansas)
ABSTRACT A method for enhancing amidohydrolase activity of Fatty Acid Amide Hydrolase (FAAH) is disclosed. The method comprising administering a phenoxyacylethanolamide that causes the enhanced activity. The enhanced activity can have numerous effects on biological organisms including, for example, enhancing the growth of certain seedlings. The subject matter disclosed herein relates to enhancers of amidohydrolase activity.
FILED Friday, January 17, 2014
APPL NO 14/761826
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 37/20 (20130101) Original (OR) Class
A01N 39/04 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474809 Santra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
APPLICANT(S) Swadeshmukul Santra (Orlando, Florida);  James Turkson (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Swadeshmukul Santra (Orlando, Florida);  James Turkson (Orlando, Florida)
ABSTRACT An activatable nanoprobe is provided having a core component and an active agent associated with the core component via a bond configured to be cleaved upon exposure to an endogenous compound.
FILED Tuesday, June 24, 2014
APPL NO 14/313372
ART UNIT 1671 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0067 (20130101)
A61K 49/1833 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475013 Abate et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Adam R. Abate (San Francisco, California);  David A. Weitz (Bolton, Massachusetts)
ABSTRACT The present invention generally relates to systems and methods for creating droplets. In one aspect, a plurality of droplets (27) is introduced into a continuous fluid stream (21) to cause the continuous fluid stream to form discrete droplets. In some cases, the droplets that are formed from the continuous fluid stream may be substantially monodisperse. The continuous fluid stream may, in some cases, be a jetting fluid stream flowing at a relatively high linear flow rate, and in certain embodiments, high rates of droplet formation from the jetting fluid may thereby be achieved. Additionally, certain aspects of the invention are generally directed to devices, such as microfluidic devices, able to form such droplets. For example, in one set of embodiments, a device may include a junction (14) where a plurality of droplets (27) can be introduced into a continuous fluid stream (21), and optionally, the device may include additional junctions (12) able to cause the formation of the plurality of droplets and/or the formation of the continuous fluid stream. Still other disclosed aspects are generally directed to methods of making such devices, methods of using such devices, kits involving such devices, and the like.
FILED Thursday, February 07, 2013
APPL NO 14/377267
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 3/0803 (20130101) Original (OR) Class
B01F 3/0807 (20130101)
B01F 3/0865 (20130101)
B01F 5/0085 (20130101)
B01F 5/0471 (20130101)
B01F 13/0059 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0241 (20130101)
B01L 3/50273 (20130101)
B01L 3/502776 (20130101)
B01L 3/502784 (20130101)
B01L 2200/0673 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/0318 (20150401)
Y10T 137/87587 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475023 Bindra et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
Directorate of Environmental Research and Education (ERE)
APPLICANT(S) Hitesh Bindra (Fort Lee, New Jersey);  Pablo Bueno (New York, New York)
ASSIGNEE(S) The Research Foundation of the City University of New York (New York, New York)
INVENTOR(S) Hitesh Bindra (Fort Lee, New Jersey);  Pablo Bueno (New York, New York)
ABSTRACT Methods and systems for optimizing the process of heat and/or mass transfer operations in packed beds and embodiments of applications of the methods are disclosed herein below. In one instance, the method results in the profile of the quantity representative of the heat and/or mass transfer operation having a propagating substantially sharp front.
FILED Tuesday, January 10, 2012
APPL NO 14/234286
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/04 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0006 (20130101) Original (OR) Class

Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles
F01K 23/10 (20130101)

Methods of Steam Generation; Steam Boilers
F22B 1/028 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 17/02 (20130101)
F28D 20/00 (20130101)
F28D 20/0056 (20130101)
F28D 2020/0069 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 20/16 (20130101)
Y02E 60/142 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475028 Krishna et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Vijay Krishna (Gainesville, Florida);  Brij Moudgil (Gainesville, Florida);  Ben Koopman (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Vijay Krishna (Gainesville, Florida);  Brij Moudgil (Gainesville, Florida);  Ben Koopman (Gainesville, Florida)
ABSTRACT A method of irradiating a target region containing at least one fullerene comprising molecule promotes the heating or combustion of the target region. The heating method can be employed in a variety of applications including: selective targeting and destruction of cancer cells, detonation of explosives, ignition of a combustible mixture, photolithographic processes, and writing of optical storage media.
FILED Friday, June 05, 2009
APPL NO 12/479300
ART UNIT 3742 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/00 (20130101)
A61N 5/10 (20130101)
A61N 5/062 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/121 (20130101)
B01J 19/123 (20130101) Original (OR) Class
B01J 19/125 (20130101)
B01J 19/126 (20130101)
B01J 19/127 (20130101)
B01J 19/128 (20130101)
B01J 19/129 (20130101)

Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 23/001 (20130101)

Detonating or Priming Devices; Fuses; Chemical Lighters; Pyrophoric Compositions
C06C 9/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475777 Miljanić et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S) Ognjen {hacek over (S)} Miljanić (Houston, Texas);  Teng-Hao Chen (Houston, Texas);  Ilya Popov (Houston, Texas);  Watchareeya Kaveevivitchai (Houston, Texas);  Olafs Daugulis (Houston, Texas)
ABSTRACT Porous partially fluorinated materials which bind aliphatic and aromatic hydrocarbons, fluorocarbons and freons with high weight adsorption capacities are provided. Such compounds may be used in separation of materials by exclusion such as selective separation of isomers of xylene.
FILED Friday, May 08, 2015
APPL NO 14/707812
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101)

Heterocyclic Compounds
C07D 231/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476026 Arinzeh et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) New Jersey Institute of Technology (Newark, New Jersey)
ASSIGNEE(S) New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) Treena Arinzeh (West Orange, New Jersey);  George Collins (Maplewood, New Jersey);  Yee-Shuan Lee (Keamy, New Jersey)
ABSTRACT Provided is an electroactive structure and method for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure.
FILED Friday, October 12, 2012
APPL NO 13/651296
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/16 (20130101)
A61L 27/16 (20130101)
A61L 27/16 (20130101)
A61L 27/54 (20130101)
A61L 27/3834 (20130101)
A61L 2300/414 (20130101)
A61L 2400/12 (20130101)
A61L 2430/02 (20130101)
A61L 2430/06 (20130101)

Compositions of Macromolecular Compounds
C08L 27/12 (20130101)
C08L 27/16 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0618 (20130101) Original (OR) Class
C12N 2529/00 (20130101)
C12N 2533/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476032 Wimmer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Experimental and Integrative Activities (EIA)
APPLICANT(S) Eckard Wimmer (East Setauket, New York);  Steve Skiena (Setauket, New York);  Steffen Mueller (Kings Point, New York);  Bruce Futcher (Stony Brook, New York);  Dimitris Papamichail (South Miami, Florida);  John Robert Coleman (Blauvelt, New York);  Jeronimo Cello (Port Jefferson, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Eckard Wimmer (East Setauket, New York);  Steve Skiena (Setauket, New York);  Steffen Mueller (Kings Point, New York);  Bruce Futcher (Stony Brook, New York);  Dimitris Papamichail (South Miami, Florida);  John Robert Coleman (Blauvelt, New York);  Jeronimo Cello (Port Jefferson, New York)
ABSTRACT This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus.
FILED Monday, March 31, 2008
APPL NO 12/594173
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/5254 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2720/12361 (20130101)
C12N 2740/15061 (20130101)
C12N 2760/16061 (20130101)
C12N 2770/20061 (20130101)
C12N 2770/24161 (20130101)
C12N 2770/32061 (20130101)
C12N 2770/32661 (20130101)
C12N 2770/32761 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476040 Mackenzie et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
APPLICANT(S) Sally Ann Mackenzie (Lincoln, Nebraska);  Roberto De la Rosa Santamaria (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
INVENTOR(S) Sally Ann Mackenzie (Lincoln, Nebraska);  Roberto De la Rosa Santamaria (Lincoln, Nebraska)
ABSTRACT The present invention provides methods for obtaining plants that exhibit useful traits by transient suppression of the MSH1 gene of the plants. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants.
FILED Wednesday, May 02, 2012
APPL NO 13/462216
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 1/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 15/8218 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476090 Brown, III et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Carl Brown, III (Albuquerque, New Mexico);  Steven Wayde Graves (Santa Fe, New Mexico);  Darko Stefanovic (Albuquerque, New Mexico);  Matthew Richard Lakin (Albuquerque, New Mexico)
ABSTRACT This disclosure describes a structured polynucleotide, devices that include the structured polynucleotide, and methods involving the structured polynucleotide and/or devices. Generally, the structured polynucleotide includes five domains. A first domain acts as a toehold for an input DNA logic gate to initiate binding to an SCS biomolecule. A second domain acts as a substrate recognition sequence for an upstream DNA logic gate. A third domain acts as a toehold for a output DNA logic gate to initiate binding of the SCS biomolecule to the gate. A fourth domain acts as an effector sequence to alter the state of the output logic gate. A fifth domain acts as a cage sequence to lock the effector sequence in an inactive state until an input gate binds to the structured polynucleotide.
FILED Wednesday, May 21, 2014
APPL NO 14/283993
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101) Original (OR) Class
C12Q 1/6816 (20130101)
C12Q 2521/345 (20130101)
C12Q 2525/301 (20130101)
C12Q 2565/1015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476648 Sun et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Ying Sun (Merion Station, Pennsylvania);  Matthew McCarthy (Media, Pennsylvania);  Young I. Cho (Cherry Hill, New Jersey);  Philipp Boettcher (Philadelphia, Pennsylvania);  Han Hu (Philadelphia, Pennsylvania);  Baolan Shi (Palo Alto, California);  Qinghua Xie (Reading, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Ying Sun (Merion Station, Pennsylvania);  Matthew McCarthy (Media, Pennsylvania);  Young I. Cho (Cherry Hill, New Jersey);  Philipp Boettcher (Philadelphia, Pennsylvania);  Han Hu (Philadelphia, Pennsylvania);  Baolan Shi (Palo Alto, California);  Qinghua Xie (Reading, Pennsylvania)
ABSTRACT Cooling systems and methods for cooling in a power plant using a phase change material. In one embodiment, a phase change material container includes at least one phase change material which may be in the form of a slurry; and at least one conduit for transporting the fluid through the phase change material when located in the phase change material container. The system may also comprise an air flow chamber; and a phase change material flow system including a pump for pumping phase change material from an outlet of phase change material container, to at least one phase change material spray nozzle. The phase change material flow system is configured to ensure that solidified phase change material is returned to the phase change material container.
FILED Wednesday, January 21, 2015
APPL NO 14/601616
ART UNIT 3744 — Fluid Handling and Dispensing
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 3/0473 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction
F28C 3/10 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 1/0233 (20130101) Original (OR) Class
F28D 11/00 (20130101)
F28D 20/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476768 DeFlores et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Lauren DeFlores (Cambridge, Massachusetts);  Andrei Tokmakoff (Lexington, Massachusetts)
ABSTRACT The present invention relates to a system and methods for acquiring two-dimensional Fourier transform (2D FT) spectra. Overlap of a collinear pulse pair and probe induce a molecular response which is collected by spectral dispersion of the signal modulated probe beam. Simultaneous collection of the molecular response, pulse timing and characteristics permit real time phasing and rapid acquisition of spectra. Full spectra are acquired as a function of pulse pair timings and numerically transformed to achieve the full frequency-frequency spectrum. This method demonstrates the ability to acquire information on molecular dynamics, couplings and structure in a simple apparatus. Multi-dimensional methods can be used for diagnostic and analytical measurements in the biological, biomedical, and chemical fields.
FILED Wednesday, July 31, 2013
APPL NO 13/955158
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101) Original (OR) Class
G01J 3/2803 (20130101)
G01J 3/2823 (20130101)
G01J 3/4531 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/35 (20130101)
G01N 2021/3595 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476819 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) Tza-Huei Jeff Wang (Timonium, Maryland);  Kelvin Jeng-Fang Liu (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Tza-Huei Jeff Wang (Timonium, Maryland);  Kelvin Jeng-Fang Liu (Baltimore, Maryland)
ABSTRACT A method of separating, detecting and determining a size of each of a plurality of particles in a fluid includes compelling the fluid to flow through a fluid channel such that larger particles of the plurality of particles travel through the fluid channel faster than smaller particles of the plurality of particles; illuminating a detection zone of the fluid channel substantially uniformly across an entire cross section of the fluid channel such that each of the plurality of particles passes through illumination light upon passing through the detection zone; detecting each of the plurality of particles based on corresponding responses to the illuminating to determine a time that each of the plurality of particles passes through the detection zone; and determining a size of each of the plurality of particles based on the time that each of the plurality of particles passes through the detection zone.
FILED Wednesday, October 19, 2011
APPL NO 13/822986
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/686 (20130101)
C12Q 2565/629 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/0255 (20130101)
G01N 15/1484 (20130101) Original (OR) Class
G01N 21/645 (20130101)
G01N 33/48 (20130101)
G01N 2015/149 (20130101)
G01N 2015/1486 (20130101)
G01N 2015/1493 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476824 Ben-Amotz et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Dor Ben-Amotz (West Lafayette, Indiana);  Bradley J. Lucier (West Lafayette, Indiana);  Gregery T. Buzzard (West Lafayette, Indiana);  David Wilcox (Carmel, Indiana);  Ping Wang (West Lafayette, Indiana);  Bharat R. Mankani (West Lafayette, Indiana)
ABSTRACT A method for measuring a sample to identify a chemical includes receiving respective spectra for each of a plurality of chemicals. Using a processor, a plurality of binary mathematical filters are computed using the received spectra. A spatial light modulator is adjusted according to a selected mathematical filter. Light that has interacted with the sample is dispersed over the surface of the spatial light modulator, so that the spatial light modulator provides light at wavelengths corresponding to the selected mathematical filter. The light provided by the spatial light modulator is measured to provide a score corresponding to the selected mathematical filter. Filter scores are combined to determine a chemical amount. The processor can operate detection apparatus having a light source, an objective for focusing source light onto the sample, a spatial light modulator, and a detector for detecting the modulator output.
FILED Tuesday, October 15, 2013
APPL NO 14/054149
ART UNIT 2862 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/44 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/25 (20130101) Original (OR) Class
G01N 21/65 (20130101)
G01N 2201/129 (20130101)
G01N 2201/0675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476862 Motayed et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland);  The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia);  George Mason University (Fairfax, Virginia);  The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  The United States of America, as Represented by the Secretary of Commerce, National Institute of Standards and Technology (Washington, District of Columbia);  George Mason University (Fairfax, Virginia);  The George Washington University (Washington, District of Columbia)
INVENTOR(S) Abhishek Motayed (Rockville, Maryland);  Geetha Aluri (Clifton Park, New York);  Albert V. Davydov (North Potomac, Maryland);  Mulpuri V. Rao (Fairfax Station, Virginia);  Vladimir P. Oleshko (Gaithersburg, Maryland);  Ritu Bajpai (Santa Clara, California);  Mona E. Zaghloul (Bethesda, Maryland)
ABSTRACT A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte.
FILED Friday, April 12, 2013
APPL NO 13/861962
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3278 (20130101)
G01N 27/4146 (20130101)
G01N 33/0031 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476951 Orozco et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Antonio Orozco (Washington, District of Columbia);  Vladimir V. Talanov (Ellicott City, Maryland);  Alfred Benjamin Cawthorne, III (Franklin, Tennessee);  Nesco Mario Lettsome, Jr. (Beltsville, Maryland)
ASSIGNEE(S) Neocera, LLC (Beltsville, Maryland)
INVENTOR(S) Antonio Orozco (Washington, District of Columbia);  Vladimir V. Talanov (Ellicott City, Maryland);  Alfred Benjamin Cawthorne, III (Franklin, Tennessee);  Nesco Mario Lettsome, Jr. (Beltsville, Maryland)
ABSTRACT An RF DC SQUID based magnetometer capable of sensing coherent magnetic fields up to 200 MHz and higher is developed which overcomes frequency limitations associated with noise signals due to transmission line delays between the SQUID circuit and readout electronics. The bandwidth limitations are overcome by superimposing the RF flux on the modulation flux to produce at the SQUID output a binary phase modulated RF voltage, which is processed to lock the static flux, and to control modulation regime by producing an AC bias for the RF flux. RF readout electronics based on a double lock-in technique (sequential demodulation of the RF SQUID voltage at the modulation flux frequency ωm and the RF flux frequency ωRF), yields a signal proportional to the product of amplitude and phase cosine of RF flux with linear dynamic range up to five orders in magnitude if compared to DC SQUID operated in traditional flux-locked loop regime.
FILED Monday, November 14, 2011
APPL NO 14/351374
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/035 (20130101)
G01R 33/0356 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477061 Kubala et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) FiveFocal LLC (Boulder, Colorado)
ASSIGNEE(S) FiveFocal LLC (Boulder, Colorado)
INVENTOR(S) Kenneth Scott Kubala (Boulder, Colorado);  Alan E. Baron (Boulder, Colorado);  Robert Matthew Bates (Erie, Colorado);  Jeremy Alan Grata (Longmont, Colorado)
ABSTRACT An infrared imaging system is formed by passively aligning two or more lens wafers including a plurality of lenses. The lens wafers may be pre-fabricated lens wafers in which the plurality of lenses are aligned utilizing an alignment jig having a plurality of conduits for distributing bonding material. Alternatively, the lens wafers may be formed of a base material molded around the plurality of optical lenses. The lens wafers may have a variety of alignment features, alignment inserts and/or alignment elements.
FILED Thursday, July 25, 2013
APPL NO 13/951414
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 7/021 (20130101) Original (OR) Class
G02B 13/18 (20130101)
G02B 13/146 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477233 Ismagilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) Rustem F. Ismagilov (Chicago, Illinois);  Bo Zheng (Chicago, Illinois);  Cory J. Gerdts (Chicago, Illinois)
ASSIGNEE(S) THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S) Rustem F. Ismagilov (Chicago, Illinois);  Bo Zheng (Chicago, Illinois);  Cory J. Gerdts (Chicago, Illinois)
ABSTRACT A microfluidic system with a plurality of sequential T-junctions for performing reactions in a plurality of droplets (plugs) of micro- to femtoliter volumes is disclosed. The microfluidic system is configured such that the plurality of plugs are flowing through a loading component, with the loading component splitting the plurality of plugs at each of the plurality of downstream T-junctions and each inlet of the plurality of detachable holding components is configured to be operably coupled with at least one of outlets of the plurality of downstream T-junctions so that the holding components received a plurality of split plugs in the immiscible carrier fluid from the loading component.
FILED Friday, July 01, 2005
APPL NO 11/174298
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 5/0471 (20130101)
B01F 13/0071 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0059 (20130101)
B01J 2219/00522 (20130101)
B01J 2219/00585 (20130101)
B01J 2219/00599 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0293 (20130101)
B01L 3/502746 (20130101)
B01L 3/502784 (20130101)
B01L 2200/0673 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 35/08 (20130101)
G01N 2035/1034 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 7/0694 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 137/0318 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477307 Chizeck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
APPLICANT(S) University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) The University of Washington (Seattle, Washington)
INVENTOR(S) Howard Jay Chizeck (Mercer Island, Washington);  Fredrik Ryden (Seattle, Washington)
ABSTRACT Methods, articles of manufacture, and devices related to generating six degree of freedom (DOF) haptic feedback are provided. A computing device can receive first depth data about an environment. The computing device can generate a first plurality of points from the first depth data. The computing device can determine a virtual tool, where the virtual tool is specified in terms of a translation component for the virtual tool and a rotation component for the virtual tool. The computing device can determine a first force vector between the virtual tool and the first plurality of points. The computing device can send a first indication of haptic feedback based on the first force vector.
FILED Friday, January 24, 2014
APPL NO 14/164114
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/25 (20160201)

Electric Digital Data Processing
G06F 3/016 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 15/04 (20130101)

Pictorial Communication, e.g Television
H04N 5/2256 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478026 Jensen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) MUSC Foundation for Research Development (Charleston, South Carolina);  Golbarg Tarighat Saber (Charleston, South Carolina)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina)
INVENTOR(S) Jens Jensen (Charleston, South Carolina);  Ali Tabesh (Charleston, South Carolina);  Joseph Helpern (Sullivans Island, South Carolina)
ABSTRACT One aspect of the present disclosure relates to a system that can determine a kurtosis diffusion orientation distribution function (dODF) that can, for example, be used with diffusional kurtosis imaging fiber tractography (DKI-FT). The system can include a non-transitory memory storing computer-executable instructions and a processor that executes the computer-executable instructions to perform the following operations. Diffusion magnetic resonance imaging (dMRI) data can be received. Based on the dMRI data, a diffusion tensor (DT) and a diffusional kurtosis tensor (DKT) can be determined. A kurtosis dODF can be determined for the dMRI data based on the DT and the DKT. The kurtosis dODF extends a Gaussian approximation of the DT to include non-Gaussian corrections of the DKT.
FILED Tuesday, March 31, 2015
APPL NO 14/673991
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101)
A61B 5/168 (20130101)
A61B 5/4088 (20130101)
A61B 5/4094 (20130101)
A61B 2576/026 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/56341 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/0081 (20130101)
G06T 2207/10092 (20130101)
G06T 2207/30016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478038 Boriah et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Shyam Boriah (Cambridge, Massachusetts);  Vipin Kumar (Minneapolis, Minnesota);  Varun Mithal (Minneapolis, Minnesota);  Ankush Khandelwal (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Shyam Boriah (Cambridge, Massachusetts);  Vipin Kumar (Minneapolis, Minnesota);  Varun Mithal (Minneapolis, Minnesota);  Ankush Khandelwal (Minneapolis, Minnesota)
ABSTRACT A method reduces processing time required to identify locations burned by fire by receiving a feature value for each pixel in an image, each pixel representing a sub-area of a location. Pixels are then grouped based on similarities of the feature values to form candidate burn events. For each candidate burn event, a probability that the candidate burn event is a true burn event is determined based on at least one further feature value for each pixel in the candidate burn event. Candidate burn events that have a probability below a threshold are removed from further consideration as burn events to produce a set of remaining candidate burn events.
FILED Monday, March 30, 2015
APPL NO 14/673018
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101)
G06K 9/209 (20130101)
G06K 9/4638 (20130101)
G06K 9/6218 (20130101)
G06K 9/6256 (20130101)

Image Data Processing or Generation, in General
G06T 7/0081 (20130101) Original (OR) Class
G06T 2207/20021 (20130101)
G06T 2207/30181 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478361 Logue et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) South Dakota Board of Regents (Brookings, South Dakota)
ASSIGNEE(S) South Dakota Board of Regents (Brookings, South Dakota)
INVENTOR(S) Brian A. Logue (Aurora, South Dakota);  Mahdi Farrakh Baroughi (Brookings, South Dakota);  Venkataiah Mallam (Andhrapradesh, India)
ABSTRACT Self-assembled monolayer hybrid materials having a modified carboxylic acid deposited from the gas-phase onto a metal oxide substrate, methods of using targeted α-carbon modified carboxylic acids to rapidly deposit activated organic molecules into a self-assembled monolayer on metal oxide substrates, and the self-assembled monolayer hybrid materials capable of being used in various industries, such as optoelectronics and separation science.
FILED Thursday, September 04, 2014
APPL NO 14/477344
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/60 (20130101)
B05D 1/185 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/12 (20130101)
C23C 16/4485 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/2031 (20130101)
H01G 9/2059 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/542 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478403 Lozano et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Paulo C. Lozano (Arlington, Massachusetts);  Steven Mark Arestie (Redondo Beach, California)
ABSTRACT An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or room-temperature molten salt. The body can have a pore size gradient that decreases from the base of the body to the tip of the body, such that the at least one of an ionic liquid or room-temperature molten salt is capable of being transported through capillarity from the base to the tip.
FILED Monday, July 21, 2014
APPL NO 14/336814
ART UNIT 2881 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/14 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 1/05 (20130101)
H01J 9/02 (20130101)
H01J 37/08 (20130101)
H01J 49/0445 (20130101) Original (OR) Class
H01J 2237/0802 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478852 Werner et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Douglas H. Werner (State College, Pennsylvania);  Zhihao Jiang (State College, Pennsylvania)
ABSTRACT An antenna includes a first body having an array of resonators; a spacer adjacent to the first body, and a second body adjacent to the spacer such that the spacer is between the first and second bodies. The first body can be configured as an artificial metasurface ground plane and the second body can be configured as a monopole.
FILED Tuesday, August 19, 2014
APPL NO 14/462780
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/48 (20130101) Original (OR) Class
H01Q 1/52 (20130101)
H01Q 1/273 (20130101)
H01Q 15/0013 (20130101)
H01Q 15/0086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479192 Jalali et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Bahram Jalali (Los Angeles, California);  Mohammad H. Asghari (Los Angeles, California)
ABSTRACT A method and apparatus for compression of digital and analog data utilizing an anamorphic spectrum transformation to warp an analog or digital signal to provide time-bandwidth compression after sampling is performed on the warped signal. The anamorphic spectrum transformation performs reallocating samples to assign more samples to fine features with high frequency waveform portions and fewer samples to coarse features with low frequency portions of the analog temporal signal, resulting in shorter record length and fewer number of samples.
FILED Wednesday, June 24, 2015
APPL NO 14/749626
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 5/22 (20130101) Original (OR) Class
H03M 7/3059 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479483 Erickson
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) John S. Erickson (Norwich, Vermont)
ASSIGNEE(S) Digimarc Corporation (Beaverton, Oregon)
INVENTOR(S) John S. Erickson (Norwich, Vermont)
ABSTRACT An apparatus to render content according to pre-established permissions associated with the content is provided. The apparatus includes: i) electronic processing circuitry; ii) executable instructions for execution by the processing circuitry, and iii) an output to render content. The executable instructions include instructions to control rendering of content according to pre-established permissions associated with the content. At a minimum, the rendering provides at least a preview of the content. The instructions further include instructions to facilitate communication with an external processor to obtain at least one of: i) content; and ii) supplemental permissions. The supplemental permissions extend permissible rendering of the content beyond the pre-established permissions.
FILED Tuesday, May 04, 2004
APPL NO 10/839328
ART UNIT 2437 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/10 (20130101)
G06F 2211/007 (20130101)
G06F 2211/008 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/105 (20130101)
H04L 63/123 (20130101)
H04L 63/126 (20130101)
H04L 63/0428 (20130101) Original (OR) Class
H04L 2463/103 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479685 Ng et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
INVENTOR(S) Yi-Ren Ng (Mountain View, California);  Patrick Hanrahan (Portola Valley, California);  Marc S. Levoy (Stanford, California);  Mark A. Horowitz (Menlo Park, California)
ABSTRACT Image data is processed to facilitate focusing and/or optical correction. According to an example embodiment of the present invention, an imaging arrangement collects light data corresponding to light passing through a particular focal plane. The light data is collected using an approach that facilitates the determination of the direction from which various portions of the light incident upon a portion of the focal plane emanate from. Using this directional information in connection with value of the light as detected by photosensors, an image represented by the light is selectively focused and/or corrected.
FILED Wednesday, December 17, 2014
APPL NO 14/573991
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/0056 (20130101)
G02B 27/0075 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/14627 (20130101)

Pictorial Communication, e.g Television
H04N 5/2173 (20130101)
H04N 5/2254 (20130101) Original (OR) Class
H04N 5/23212 (20130101)
H04N 5/23232 (20130101)
H04N 5/23293 (20130101)
H04N 13/0235 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 09474829 Kentner et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Space Biomedical Research Institute (NSBRI)
APPLICANT(S) ACell, Inc. (Columbia, Maryland)
ASSIGNEE(S) ACell, Inc. (Columbia, Maryland)
INVENTOR(S) Kimberly A. Kentner (Columbia, Maryland);  Katherine A. Stuart (Columbia, Maryland);  Abram D. Janis (Columbia, Maryland)
ABSTRACT The present invention is directed to methods of manufacturing bioactive gels from ECM material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ECM material can be created by digesting particularized ECM material in an alkaline environment and neutralizing to provide bioactive gels.
FILED Tuesday, December 15, 2015
APPL NO 14/969800
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101)
A61K 35/12 (20130101)
A61K 35/22 (20130101)
A61K 38/18 (20130101)
A61K 38/1825 (20130101)
A61K 38/1866 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/22 (20130101)
A61L 27/50 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/3633 (20130101) Original (OR) Class
A61L 27/3683 (20130101)
A61L 27/3687 (20130101)
A61L 27/3691 (20130101)
A61L 2300/252 (20130101)
A61L 2300/412 (20130101)
A61L 2300/414 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475199 Burridge et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Johnson Space Center (JSC)
APPLICANT(S) TRACLabs, Inc. (Webster, Texas)
ASSIGNEE(S) TRACLabs, Inc. (Webster, Texas)
INVENTOR(S) Robert Raven Burridge (Houston, Texas);  Mars Wei Chu (Houston, Texas);  Bryn Tyler Wolfe (League City, Texas)
ABSTRACT A robotic manipulator arm is disclosed. The arm includes joints that are attachable and detachable in a tool-free manner via a universal mating adapter. The universal mating adapter includes a built-in electrical interface for an operative electrical connection upon mechanical coupling of the adapter portions. The universal mating adapter includes mechanisms and the ability to store and communicate parameter configurations such that the joints can be rearranged for immediate operation of the arm without further reprogramming, recompiling, or other software intervention.
FILED Wednesday, June 05, 2013
APPL NO 13/911073
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/06 (20130101)
B25J 9/08 (20130101)
B25J 13/088 (20130101)
B25J 17/00 (20130101) Original (OR) Class
B25J 17/025 (20130101)
B25J 19/0004 (20130101)
B25J 19/0033 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 74/20329 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475579 Fredericks et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) William J. Fredericks (Williamsburg, Virginia);  Mark D. Moore (Williamsburg, Virginia);  Ronald C. Busan (Newport News, Virginia);  Paul M. Rothhaar (Newport News, Virginia);  David D. North (Williamsburg, Virginia);  William M. Langford (Hampton, Virginia);  Christopher T. Laws (Newport News, Virginia);  William T. Hodges (Yorktown, Virginia);  Zachary R. Johns (Virginia Beach, Virginia);  Sandy R. Webb (Hampton, Virginia)
ABSTRACT Systems, methods, and devices are provided that combine an advance vehicle configuration, such as an advanced aircraft configuration, with the infusion of electric propulsion, thereby enabling a four times increase in range and endurance while maintaining a full vertical takeoff and landing (“VTOL”) and hover capability for the vehicle. Embodiments may provide vehicles with both VTOL and cruise efficient capabilities without the use of ground infrastructure. An embodiment vehicle may comprise a wing configured to tilt through a range of motion, a first series of electric motors coupled to the wing and each configured to drive an associated wing propeller, a tail configured to tilt through the range of motion, a second series of electric motors coupled to the tail and each configured to drive an associated tail propeller, and an electric propulsion system connected to the first series of electric motors and the second series of electric motors.
FILED Wednesday, August 13, 2014
APPL NO 14/121001
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 3/40 (20130101)
B64C 3/385 (20130101)
B64C 9/14 (20130101)
B64C 11/50 (20130101)
B64C 25/32 (20130101)
B64C 29/0033 (20130101) Original (OR) Class
B64C 39/024 (20130101)
B64C 2201/042 (20130101)
B64C 2201/044 (20130101)
B64C 2201/108 (20130101)
B64C 2201/165 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/24 (20130101)
B64D 27/26 (20130101)
B64D 2027/026 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 903/903 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475594 Barber et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Goddard Space Flight Center (GSFC)
APPLICANT(S) HONEYWELL INTERNATIONAL INC. (Morristown, New Jersey)
ASSIGNEE(S) HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
INVENTOR(S) Tim Daniel Barber (Litchfield Park, Arizona);  Ken Young (Peoria, Arizona);  Timothy Hindle (Peoria, Arizona)
ABSTRACT Launch lock assemblies with reduced preload are provided. The launch lock assembly comprises first and second mount pieces, a releasable clamp device, and a pair of retracting assemblies. Each retracting assembly comprises a pair of toothed members having interacting toothed surfaces. The releasable clamp device normally maintains the first and second mount pieces in clamped engagement. When the releasable clamp device is actuated, the first and second mount pieces are released from clamped engagement and one toothed member of each retracting assembly moves in an opposite direction relative to the other one toothed member of the other retracting assembly to define an axial gap on each side of the first mount piece.
FILED Tuesday, September 25, 2012
APPL NO 13/626843
ART UNIT 3632 — Static Structures, Supports and Furniture
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/283 (20130101)
B64G 1/285 (20130101)
B64G 1/286 (20130101)
B64G 1/641 (20130101) Original (OR) Class
B64G 2001/228 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09475973 Southward et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Robin E. Southward (Stanwood, Washington);  Donavon Mark Delozier (Disputanta, Virginia);  Kent A. Watson (New Kent, Virginia);  Joseph G. Smith, Jr. (Smithfield, Virginia);  Sayata Ghose (Sammamish, Washington);  John W. Connell (Yorktown, Virginia)
ABSTRACT In the method of embodiments of the invention, the metal seeded carbon allotropes are reacted in solution forming zero valent metallic nanowires at the seeded sites. A polymeric passivating reagent, which selects for anisotropic growth is also used in the reaction to facilitate nanowire formation. The resulting structure resembles a porcupine, where carbon allotropes have metallic wires of nanometer dimensions that emanate from the seed sites on the carbon allotrope. These sites are populated by nanowires having approximately the same diameter as the starting nanoparticle diameter.
FILED Wednesday, March 26, 2014
APPL NO 14/225757
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0025 (20130101)
B22F 1/0025 (20130101)
B22F 1/0025 (20130101)
B22F 1/025 (20130101)
B22F 9/24 (20130101)
B22F 2998/00 (20130101)
B22F 2998/00 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 31/04 (20130101)
C01B 31/022 (20130101)
C01B 31/0206 (20130101)
C01B 31/0213 (20130101)
C01B 31/0423 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/005 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 5/14 (20130101) Original (OR) Class

Alloys
C22C 1/058 (20130101)
C22C 1/1084 (20130101)
C22C 26/00 (20130101)
C22C 2026/001 (20130101)
C22C 2026/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476113 Padula, II
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Santo A. Padula, II (Valley City, Ohio)
ABSTRACT Methods and apparatuses for stabilizing the strain-temperature response for a shape memory alloy are provided. To perform stabilization of a second sample of the shape memory alloy, a first sample of the shape memory alloy is selected for isobaric treatment and the second sample is selected for isothermal treatment. When applying the isobaric treatment to the first sample, a constant stress is applied to the first sample. Temperature is also cycled from a minimum temperature to a maximum temperature until a strain on the first sample stabilizes. Once the strain on the first sample stabilizes, the isothermal treatment is performed on the second sample. During isothermal treatment, different levels of stress on the second sample are applied until a strain on the second sample matches the stabilized strain on the first sample.
FILED Wednesday, April 15, 2015
APPL NO 14/687441
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 1/00 (20130101)
C21D 11/00 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/006 (20130101) Original (OR) Class

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09476612 Cwik et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Thomas A. Cwik (La Canada, California);  Paul E. Dimotakis (Altadena, California);  Daniel J. Hoppe (La Canada, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Thomas A. Cwik (La Canada, California);  Paul E. Dimotakis (Altadena, California);  Daniel J. Hoppe (La Canada, California)
ABSTRACT The present invention relates to concentrating solar-power systems and, more particularly, beam-forming concentrating solar thermal array power systems. A solar thermal array power system is provided, including a plurality of solar concentrators arranged in pods. Each solar concentrator includes a solar collector, one or more beam-forming elements, and one or more beam-steering elements. The solar collector is dimensioned to collect and divert incoming rays of sunlight. The beam-forming elements intercept the diverted rays of sunlight, and are shaped to concentrate the rays of sunlight into a beam. The steering elements are shaped, dimensioned, positioned, and/or oriented to deflect the beam toward a beam output path. The beams from the concentrators are converted to heat at a receiver, and the heat may be temporarily stored or directly used to generate electricity.
FILED Friday, March 09, 2012
APPL NO 13/417120
ART UNIT 3748 — Fluid Handling and Dispensing
CURRENT CPC
Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 6/065 (20130101)
F03G 6/067 (20130101)

Producing or Use of Heat Not Otherwise Provided For
F24J 2/10 (20130101)
F24J 2/12 (20130101)
F24J 2/13 (20130101)
F24J 2/14 (20130101)
F24J 2/15 (20130101)
F24J 2/16 (20130101)
F24J 2/18 (20130101)
F24J 2/38 (20130101)
F24J 2/5413 (20130101) Original (OR) Class
F24J 2002/108 (20130101)
F24J 2002/109 (20130101)
F24J 2002/1004 (20130101)
F24J 2002/1019 (20130101)
F24J 2002/1023 (20130101)
F24J 2002/1061 (20130101)
F24J 2002/1076 (20130101)
F24J 2002/1085 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/46 (20130101)
Y02E 10/47 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477795 Witzberger et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Kevin Witzberger (Cleveland, Ohio);  Jeffery Hojnicki (Cleveland, Ohio);  David Manzella (Cleveland, Ohio)
ABSTRACT Modeling and control software that integrates the complexities of solar array models, a space environment, and an electric propulsion system into a rigid body vehicle simulation and control model is provided. A rigid body vehicle simulation of a solar electric propulsion (SEP) vehicle may be created using at least one solar array model, at least one model of a space environment, and at least one model of a SEP propulsion system. Power availability and thrust profiles may be determined based on the rigid body vehicle simulation as the SEP vehicle transitions from a low Earth orbit (LEO) to a higher orbit or trajectory. The power availability and thrust profiles may be displayed such that a user can use the displayed power availability and thrust profiles to determine design parameters for an SEP vehicle mission.
FILED Friday, June 21, 2013
APPL NO 13/923441
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/5009 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477857 Youngquist et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida);  The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida);  The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Robert C. Youngquist (Cocoa, Florida);  Donald Malocha (Winter Springs, Florida);  Nancy Saldanha (Baltimore, Maryland)
ABSTRACT A surface acoustic wave (SAW)-based coherence multiplexing system includes SAW tags each including a SAW transducer, a first SAW reflector positioned a first distance from the SAW transducer and a second SAW reflector positioned a second distance from the SAW transducer. A transceiver including a wireless transmitter has a signal source providing a source signal and circuitry for transmitting interrogation pulses including a first and a second interrogation pulse toward the SAW tags, and a wireless receiver for receiving and processing response signals from the SAW tags. The receiver receives scrambled signals including a convolution of the wideband interrogation pulses with response signals from the SAW tags and includes a computing device which implements an algorithm that correlates the interrogation pulses or the source signal before transmitting against the scrambled signals to generate tag responses for each of the SAW tags.
FILED Wednesday, August 07, 2013
APPL NO 13/961521
ART UNIT 2686 — AI & Simulation/Modeling
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 2006/12164 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/02 (20130101) Original (OR) Class
G06K 7/10306 (20130101)
G06K 19/0675 (20130101)

Transmission
H04B 10/61 (20130101)
H04B 10/616 (20130101)

Multiplex Communication
H04J 14/00 (20130101)
H04J 14/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478038 Boriah et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Shyam Boriah (Cambridge, Massachusetts);  Vipin Kumar (Minneapolis, Minnesota);  Varun Mithal (Minneapolis, Minnesota);  Ankush Khandelwal (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Shyam Boriah (Cambridge, Massachusetts);  Vipin Kumar (Minneapolis, Minnesota);  Varun Mithal (Minneapolis, Minnesota);  Ankush Khandelwal (Minneapolis, Minnesota)
ABSTRACT A method reduces processing time required to identify locations burned by fire by receiving a feature value for each pixel in an image, each pixel representing a sub-area of a location. Pixels are then grouped based on similarities of the feature values to form candidate burn events. For each candidate burn event, a probability that the candidate burn event is a true burn event is determined based on at least one further feature value for each pixel in the candidate burn event. Candidate burn events that have a probability below a threshold are removed from further consideration as burn events to produce a set of remaining candidate burn events.
FILED Monday, March 30, 2015
APPL NO 14/673018
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101)
G06K 9/209 (20130101)
G06K 9/4638 (20130101)
G06K 9/6218 (20130101)
G06K 9/6256 (20130101)

Image Data Processing or Generation, in General
G06T 7/0081 (20130101) Original (OR) Class
G06T 2207/20021 (20130101)
G06T 2207/30181 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478842 Decrossas et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Emmanuel Decrossas (Pasadena, California);  Goutam Chattopadhyay (Pasadena, California);  Nacer Chahat (Pasadena, California);  Adrian J. Tang (Pasadena, California)
ABSTRACT A lens for interconnecting a metallic waveguide with a dielectric waveguide is provided. The lens may be coupled a metallic waveguide and a dielectric waveguide, and minimize a signal loss between the metallic waveguide and the dielectric waveguide.
FILED Monday, March 16, 2015
APPL NO 14/658411
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 5/087 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478843 Tang et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Adrian Joseph Tang (Pasadena, California);  Goutam Chattopadhyay (Pasadena, California);  Nacer E. Chahat (Pasadena, California);  Emmanuel Decrossas (Pasadena, California)
ABSTRACT A system, method, device, and apparatus provide a dielectric waveguide splitter/bi-directional link. A dielectric substrate fabricated into a first Y-junction waveguide with a first port splitting into a first branch leading to a second port and a second branch leading to a third port. An angle between the first branch and the second branch is below ninety degrees (90°). The dielectric waveguide splitter enables millimeter-wave (mmWave) transmission between the first port and the second port while reducing feedback of the mmWave between the second and third port. Two Y-junction waveguides may be fabricated back-to-back to provide simultaneous bidirectional mmWave transmission at a single frequency.
FILED Thursday, February 19, 2015
APPL NO 14/626757
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 5/12 (20130101)
H01P 5/188 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 29/49016 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479116 Milkov et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Teledyne Scientific and Imaging, LLC (Thousand Oaks, California)
ASSIGNEE(S) Teledyne Scientific and Imaging, LLC (Thousand Oaks, California)
INVENTOR(S) Mihail M. Milkov (Moorpark, California);  David J. Gulbransen (Thousand Oaks, California)
ABSTRACT A capacitive trans-impedance amplifier circuit with charge injection compensation is provided. A feedback capacitor is connected between an inverting input port and an output port of an amplifier. A MOS reset switch has source and drain terminals connected between the inverting input and output ports of the amplifier, and a gate terminal controlled by a reset signal. The reset switch is open or inactive during an integration phase, and closed or active to electrically connect the inverting input port and output port of the amplifier during a reset phase. One or more compensation capacitors are provided that are not implemented as gate oxide or MOS capacitors. Each compensation capacitor has a first port connected to a compensation signal that is a static signal or a toggling compensation signal that toggles between two compensation voltage values, and a second port connected to the inverting input port of the amplifier.
FILED Friday, March 27, 2015
APPL NO 14/671930
ART UNIT 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Amplifiers
H03F 1/0205 (20130101) Original (OR) Class
H03F 3/08 (20130101)
H03F 3/45071 (20130101)
H03F 2203/45116 (20130101)
H03F 2203/45118 (20130101)

Pictorial Communication, e.g Television
H04N 5/378 (20130101)
H04N 5/3745 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479726 Devereaux et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Throop, LLC (Los Angeles, California)
ASSIGNEE(S) THROOP, LLC (Los Angeles, California)
INVENTOR(S) Ann Devereaux (Tujunga, California);  Thomas Jedrey (Pasadena, California);  Martin Agan (Pasadena, California)
ABSTRACT The system of the present invention is a highly integrated radio communication system with a multimedia co-processor which allows true two-way multimedia (video, audio, data) access as well as real-time biomedical monitoring in a pager-sized portable access unit. The system is integrated in a network structure including one or more general purpose nodes for providing a wireless-to-wired interface. The network architecture allows video, audio and data (including biomedical data) streams to be connected directly to external users and devices. The portable access units may also be mated to various non-personal devices such as cameras or environmental sensors for providing a method for setting up wireless sensor nets from which reported data may be accessed through the portable access unit. The reported data may alternatively be automatically logged at a remote computer for access and viewing through a portable access unit, including the user's own.
FILED Monday, January 12, 2015
APPL NO 14/595191
ART UNIT 2692 — Selective Visual Display Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0015 (20130101)

Image Data Processing or Generation, in General
G06T 19/006 (20130101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 17/02 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 65/1063 (20130101)
H04L 65/1069 (20130101)
H04L 67/04 (20130101)
H04L 67/12 (20130101)

Pictorial Communication, e.g Television
H04N 7/147 (20130101) Original (OR) Class
H04N 7/152 (20130101)
H04N 7/155 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 09474272 Yang et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) North Carolina A and T State University (Greensboro, North Carolina)
ASSIGNEE(S) North Carolina A and T State University (Greensboro, North Carolina)
INVENTOR(S) Guochen Yang (Greensboro, North Carolina);  Zhongge Lu (Greensboro, North Carolina)
ABSTRACT Alexandrian laurel (Danae racemosa L.) is a highly demanded evergreen shrub. However, seed germination often takes up to 12 to 18 months with a germination rate of only about 20%. Also, due to its slow-growth rate, it typically takes up to six years to produce a saleable one-gallon size plant. Germinating seeds in the presence of cytokinins and/or auxins increased in vitro shoot multiplication and seedling quality enhancement. Benzyladenine was found to balance seedling development by simultaneously accelerating shoot growth and slowing down root growth, whereas thidiazuron significantly promoted shoot multiplication and proliferation by producing 5-30 shoots per seed.
FILED Friday, March 15, 2013
APPL NO 13/838725
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 43/08 (20130101) Original (OR) Class
A01N 43/82 (20130101)
A01N 43/90 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09474797 Borca et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia);  The University of Connecticut (Storrs, Connecticut)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia);  The University of Connecticut (Farmington, Connecticut)
INVENTOR(S) Manuel V. Borca (Westbrook, Connecticut);  Luis L. Rodriguez (Clinton, Connecticut);  Peter W. Krug (Stony Brook, New York);  Vivian K. O'Donnell (Old Saybrook, Connecticut)
ABSTRACT We have developed an ASFV Georgia strain adapted to grow in Vero cell line. The resulting virus, ASF-GVAV, efficiently grows in Vero cells although it still is able to significantly replicate in primary cell cultures of swine macrophages. ASF-GVAV virus was successfully used as parental virus to develop several recombinant ASF viruses. The development of an ASFV adapted to grow in an established cell line is a significant advance for research and development of vaccine candidate strains using genetic manipulation based in the process of homologous recombination. The GVAVS can be utilized as a basis for large scale production of ASF vaccines.
FILED Thursday, June 19, 2014
APPL NO 14/309548
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/525 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/12021 (20130101)
C12N 2710/12034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP27292 NeSmith
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Atlanta, Georgia)
INVENTOR(S) D. Scott NeSmith (Molena, Georgia)
ABSTRACT The new variety ‘TH-921’ is provided. The new and distinct variety ripens around early May in southern Georgia and late May in middle Georgia. The fruit of the new variety ‘TH-921’ are firm with good flavor and scar. The new variety ‘TH-921’ is vigorous with an estimated chilling requirement of about 500 to 550 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.
FILED Friday, July 10, 2015
APPL NO 14/545950
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/157
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 09476951 Orozco et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Antonio Orozco (Washington, District of Columbia);  Vladimir V. Talanov (Ellicott City, Maryland);  Alfred Benjamin Cawthorne, III (Franklin, Tennessee);  Nesco Mario Lettsome, Jr. (Beltsville, Maryland)
ASSIGNEE(S) Neocera, LLC (Beltsville, Maryland)
INVENTOR(S) Antonio Orozco (Washington, District of Columbia);  Vladimir V. Talanov (Ellicott City, Maryland);  Alfred Benjamin Cawthorne, III (Franklin, Tennessee);  Nesco Mario Lettsome, Jr. (Beltsville, Maryland)
ABSTRACT An RF DC SQUID based magnetometer capable of sensing coherent magnetic fields up to 200 MHz and higher is developed which overcomes frequency limitations associated with noise signals due to transmission line delays between the SQUID circuit and readout electronics. The bandwidth limitations are overcome by superimposing the RF flux on the modulation flux to produce at the SQUID output a binary phase modulated RF voltage, which is processed to lock the static flux, and to control modulation regime by producing an AC bias for the RF flux. RF readout electronics based on a double lock-in technique (sequential demodulation of the RF SQUID voltage at the modulation flux frequency ωm and the RF flux frequency ωRF), yields a signal proportional to the product of amplitude and phase cosine of RF flux with linear dynamic range up to five orders in magnitude if compared to DC SQUID operated in traditional flux-locked loop regime.
FILED Monday, November 14, 2011
APPL NO 14/351374
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/035 (20130101)
G01R 33/0356 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477061 Kubala et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) FiveFocal LLC (Boulder, Colorado)
ASSIGNEE(S) FiveFocal LLC (Boulder, Colorado)
INVENTOR(S) Kenneth Scott Kubala (Boulder, Colorado);  Alan E. Baron (Boulder, Colorado);  Robert Matthew Bates (Erie, Colorado);  Jeremy Alan Grata (Longmont, Colorado)
ABSTRACT An infrared imaging system is formed by passively aligning two or more lens wafers including a plurality of lenses. The lens wafers may be pre-fabricated lens wafers in which the plurality of lenses are aligned utilizing an alignment jig having a plurality of conduits for distributing bonding material. Alternatively, the lens wafers may be formed of a base material molded around the plurality of optical lenses. The lens wafers may have a variety of alignment features, alignment inserts and/or alignment elements.
FILED Thursday, July 25, 2013
APPL NO 13/951414
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 7/021 (20130101) Original (OR) Class
G02B 13/18 (20130101)
G02B 13/146 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09479217 Terry
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) John David Terry (Annandale, Virginia)
ASSIGNEE(S)
INVENTOR(S) John David Terry (Annandale, Virginia)
ABSTRACT The present invention teaches a system and method for cooperatively networking digital chaos transmissions. The invention involves using generated digital chaos sequences as spreading sequences at a transmit side, receiving the spreaded signals at a receive side and despreading the signal, recovering signals at the receive side, comparing a stored replica of the digital chaos spreading codes to the digital chaos spreading codes used at the transmit side to, determining if the signals belong to predefined groups based on a predetermined criteria, and forward the signals to a group member based on its group member assignment.
FILED Tuesday, July 28, 2015
APPL NO 14/811804
ART UNIT 2634 — Digital Communications
CURRENT CPC
Transmission
H04B 1/707 (20130101) Original (OR) Class

Multiplex Communication
H04J 13/0018 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 09476862 Motayed et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland);  The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia);  George Mason University (Fairfax, Virginia);  The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  The United States of America, as Represented by the Secretary of Commerce, National Institute of Standards and Technology (Washington, District of Columbia);  George Mason University (Fairfax, Virginia);  The George Washington University (Washington, District of Columbia)
INVENTOR(S) Abhishek Motayed (Rockville, Maryland);  Geetha Aluri (Clifton Park, New York);  Albert V. Davydov (North Potomac, Maryland);  Mulpuri V. Rao (Fairfax Station, Virginia);  Vladimir P. Oleshko (Gaithersburg, Maryland);  Ritu Bajpai (Santa Clara, California);  Mona E. Zaghloul (Bethesda, Maryland)
ABSTRACT A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte.
FILED Friday, April 12, 2013
APPL NO 13/861962
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3278 (20130101)
G01N 27/4146 (20130101)
G01N 33/0031 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09478429 Ghariehali et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Amir Tavakkoli Kermani Ghariehali (Tehran, Iran);  Samuel Mospens Nicaise (Cambridge, Massachusetts);  Karl K. Berggren (Arlington, Massachusetts);  Kevin Willy Gotrik (Cambridge, Massachusetts);  Caroline A. Ross (Arlington, Massachusetts)
ABSTRACT A sacrificial-post templating method is presented for directing block copolymer (BCP) self-assembly to form nanostructures of monolayers and bilayers of microdomains. The topographical post template can be removed after directing self-assembly and, therefore, is not incorporated into the final microdomain pattern. The sacrificial posts can be a material removable using a selective etchant that will not remove the material of the final pattern block(s). The sacrificial posts may be removable, at least in part, using a same etchant as for removing one of the blocks of the BCP, for example, a negative tone polymethylmethacrylate (PMMA) when a non-final pattern block of polystyrene is removed and polydimethylsiloxane (PDMS) remains on the substrate.
FILED Wednesday, March 13, 2013
APPL NO 13/800435
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00031 (20130101)
B81C 1/00111 (20130101)
B81C 1/00428 (20130101)
B81C 2201/0149 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0002 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0271 (20130101)
H01L 21/3081 (20130101) Original (OR) Class
H01L 21/31058 (20130101)
H01L 21/31138 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 09476963 Cyganski et al.
FUNDED BY
Department of Justice (DOJ)
Office of Justice Programs (OJP)
National Institute of Justice (NIJ)
APPLICANT(S) David Cyganski (Holden, Massachusetts);  R. James Duckworth (Shrewsbury, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) David Cyganski (Holden, Massachusetts);  R. James Duckworth (Shrewsbury, Massachusetts)
ABSTRACT A method for locating a transmitter using a receiver which include, but are not limited to the steps of transmitting a plurality of distinctive and orthogonally polarized signals from a transmitter; receiving the transmitted signals at a pair of separated antennas; demodulating the distinctive orthogonal signals received at each of the pair of separated antennas; and determining a direction to the transmitter from the signals received at the pair of antennas. The system for determining the location of a transmitter using a receiver includes, but is not limited to, having a transmitter adapted for orthogonally transmitting a plurality of distinctive signals; a receiver having a pair of separated antennas for receiving the orthogonally transmitted signals; separate demodulators in the receiver for each antenna of the pair of separated antennas for demodulating the distinctive signals; and signal processing circuitry in the receiver adapted for using the demodulated distinctive signals for determining a direction to the transmitter.
FILED Monday, April 25, 2011
APPL NO 13/642319
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/28 (20130101)
G01S 3/146 (20130101) Original (OR) Class
G01S 5/0205 (20130101)
G01S 11/06 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/0263 (20130101)

Antennas, i.e Radio Aerials
H01Q 21/24 (20130101)
H01Q 21/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09477905 Liu et al.
FUNDED BY
Department of Justice (DOJ)
Office of Justice Programs (OJP)
National Institute of Justice (NIJ)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Xiaoming Liu (Schenectady, New York);  Peter Henry Tu (Niskayuna, New York);  Ya Xue (Niskayuna, New York)
ABSTRACT A novel technique for unsupervised feature selection is disclosed. The disclosed methods include automatically selecting a subset of a feature of an image. Additionally, the selection of the subset of features may be incorporated with a congealing algorithm, such as a least-square-based congealing algorithm. By selecting a subset of the feature representation of an image, redundant and/or irrelevant features may be reduced or removed, and the efficiency and accuracy of least-square-based congealing may be improved.
FILED Monday, July 13, 2015
APPL NO 14/798160
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00281 (20130101)
G06K 9/623 (20130101)
G06K 9/6206 (20130101) Original (OR) Class
G06K 9/6224 (20130101)
G06K 9/6263 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 09476009 Cairncross et al.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania);  Environmental Fuel Research, LLC (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania);  Environmental Fuel Research, LLC (Philadelphia, Pennsylvania)
INVENTOR(S) Richard Allan Cairncross (Media, Pennsylvania);  Megan Elizabeth Hums (Philadelphia, Pennsylvania);  Colin James Stacy (Beaumont, Texas)
ABSTRACT The present invention provides a method of producing fatty acid alkyl esters from a lipid, comprising steps of introducing a gas comprising vapor of an alcohol selected from methanol, ethanol, 1-propanol, iso-propanol and butanols, into the lipid in a form of bubbles to enable the bubbles to pass through the lipid and be discharged from the lipid. The product may then be subjected to a transesterification process catalyzed by a base catalyst. The present invention is robust with low quality feedstocks thus significantly reduce production cost for biodiesel.
FILED Monday, April 20, 2015
APPL NO 14/690909
ART UNIT 1672 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 67/08 (20130101)

Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom
C11C 3/003 (20130101) Original (OR) Class
C11C 3/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 09474784 Wang et al.
FUNDED BY
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Xiao-jing Wang (Greenwood Village, Colorado);  Yosef Refaeli (Denver, Colorado);  Qinghong Zhang (Englewood, Colorado)
ABSTRACT The invention provides methods and compositions for the treatment of inflammatory and/or tissue damage conditions. In particular, the use of Smad7 compositions delivered locally or systematically to a site of inflammation and/or tissue damage is described. Other specific embodiments concern treatment or prevention of side effects caused by radiation and/or chemotherapy, including but not limited to mucositis.
FILED Thursday, June 25, 2015
APPL NO 14/750557
ART UNIT 1676 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 38/00 (20130101)
A61K 38/18 (20130101) Original (OR) Class
A61K 38/162 (20130101)
A61K 38/1709 (20130101)
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/16033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

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THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 25, 2016.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

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FUNDED BY
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Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2016/fedinvent-patents-20161025.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital