FedInvent™ Patents

Patent Details for Tuesday, November 08, 2016

This page was updated on Monday, March 27, 2023 at 04:54 AM GMT

Department of Health and Human Services (HHS)

09485971 — Fumarylacetoacetate hydrolase (Fah)-deficient pigs and uses thereof

US 09485971	Nyberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	May Foundation for Medical Education and Research (Rochester, Minnesota); Oregon Health and Science University (Portland, Oregon)
ASSIGNEE(S)	Oregon Health and Science University (Portland, Oregon); Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Scott Nyberg (Rochester, Minnesota); Markus Grompe (Portland, Oregon); Joseph Lillegard (Rochester, Minnesota); Raymond Hickey (Portland, Oregon)
ABSTRACT	Described herein is the generation of Fah^+/− heterozygote pigs by homologous recombination and somatic cell nuclear transfer, and a method for producing Fah^−/− homozygote pigs. The Fah-deficient pigs of the disclosure can be used for a variety of research and therapeutic purposes, such as for the expansion of human hepatocytes, and as large animal models of hereditary tyrosinemia type 1, cirrhosis and hepatocellular carcinoma.
FILED	Friday, March 13, 2015
APPL NO	14/657255
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/02 (20130101) A01K 67/0271 (20130101) Original (OR) Class A01K 67/0276 (20130101) A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2217/075 (20130101) A01K 2227/108 (20130101) A01K 2267/03 (20130101) A01K 2267/025 (20130101) A01K 2267/0331 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) C12N 5/0672 (20130101) C12N 15/861 (20130101) C12N 2750/14143 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/5067 (20130101)
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09486142 — Medical imaging devices, methods, and systems

US 09486142	Hielscher et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Andreas H. Hielscher (Brooklyn, New York); Hyun K. Kim (River Edge, New Jersey); Ludguier D. Montejo (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Andreas H. Hielscher (Brooklyn, New York); Hyun K. Kim (River Edge, New Jersey); Ludguier D. Montejo (New York, New York)
ABSTRACT	Devices, methods, and systems for providing optical imaging to detect and characterize anatomical and/or physiological indicators, such as, rheumatoid arthritis, and devices, methods and systems for computer aided detection and diagnosis of tomographic images. Embodiments for optimizing machine classification of tissue samples are described. Embodiments for using machine classification techniques to classify indicators present in optical tomographic images are described.
FILED	Tuesday, December 13, 2011
APPL NO	13/993592
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0064 (20130101) A61B 5/0073 (20130101) Original (OR) Class A61B 5/0082 (20130101) A61B 5/7264 (20130101) A61B 5/7267 (20130101) A61B 6/5211 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6271 (20130101) G06K 9/6278 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10101 (20130101) G06T 2207/20081 (20130101) G06T 2207/30008 (20130101)
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09486158 — Active adaptive detuning systems and methods for interventional devices

US 09486158	Kocaturk
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Ozgur Kocaturk (Rockville, Maryland)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Ozgur Kocaturk (Rockville, Maryland)
ABSTRACT	Active MRI compatible interventional devices, such as catheters, include at least one RF antenna so that they are visible under MRI analysis. However, metallic structures within intravascular devices may heat up significantly during interventional MRI procedures due to eddy current formation over the conductive transmission lines. The electrical field coupling that occurs between interventional devices and RF signals depend on the position and orientation of interventional device within the bore and the insertion length of the interventional device. The system detects an induced current signal during RF transmission phase and selectively adjusts the impedance value associated with the interventional device by using a varactor and integrated circuit components in such a manner that the currents induced in the interventional device are below a threshold current level, thereby controlling current levels and heating in the interventional device.
FILED	Friday, July 01, 2011
APPL NO	13/805454
ART UNIT	3737 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/285 (20130101) G01R 33/3657 (20130101) G01R 33/34084 (20130101)
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09486404 — Infarction treatment compositions and methods

US 09486404	Burdick et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Jason A. Burdick (Philadelphia, Pennsylvania); Robert C. Gorman (Lower Gwynedd, Pennsylvania); Joseph H. Gorman, III (Lower Gwynedd, Pennsylvania); Jamie L. Ifkovits (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Jason A. Burdick (Philadelphia, Pennsylvania); Robert C. Gorman (Lower Gwynedd, Pennsylvania); Joseph H. Gorman, III (Lower Gwynedd, Pennsylvania); Jamie L. Ifkovits (Philadelphia, Pennsylvania)
ABSTRACT	Provided are methods of treating cardiac infarction by using an injectable material to influence cardiac structure and remodeling after infarction. Also provided are kits that comprise an injectable material to influence cardiac structure.
FILED	Tuesday, March 27, 2012
APPL NO	13/430872
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class A61K 31/25 (20130101) A61K 31/25 (20130101) A61K 31/717 (20130101) A61K 31/717 (20130101) A61K 31/722 (20130101) A61K 31/722 (20130101) A61K 31/727 (20130101) A61K 31/727 (20130101) A61K 31/728 (20130101) A61K 31/728 (20130101) A61K 31/734 (20130101) A61K 31/734 (20130101) A61K 31/785 (20130101) A61K 31/785 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 47/32 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09486422 — Small molecule inhibitors of Mcl-1 and the uses of thereof

US 09486422	Nikolovska-Coleska et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); WAYNE STATE UNIVERSITY (Detroit, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); WAYNE STATE UNIVERSITY (Detroit, Michigan)
INVENTOR(S)	Zaneta Nikolovska-Coleska (Ann Arbor, Michigan); Hollis D. Showalter (Ann Arbor, Michigan); Chenzhong Liao (Anhui, China PRC); Ramzi Mohammad (Troy, Michigan); Fardokht Abulwerdi (Ann Arbor, Michigan)
ABSTRACT	This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having sulfonamido-1-hydroxynaphthalene structure which function as inhibitors of Mcl-1 protein, and their use as therapeutics for the treatment of cancer and other diseases.
FILED	Monday, October 08, 2012
APPL NO	14/346584
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 31/41 (20130101) A61K 31/41 (20130101) A61K 31/47 (20130101) A61K 31/47 (20130101) A61K 31/55 (20130101) A61K 31/165 (20130101) Original (OR) Class A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/216 (20130101) A61K 31/216 (20130101) A61K 31/381 (20130101) A61K 31/381 (20130101) A61K 31/402 (20130101) A61K 31/402 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 31/551 (20130101) A61K 31/664 (20130101) A61K 31/664 (20130101) A61K 31/4453 (20130101) A61K 31/4453 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 311/20 (20130101) C07C 311/21 (20130101) C07C 321/28 (20130101) C07C 323/49 (20130101) C07C 323/52 (20130101) C07C 323/60 (20130101) C07C 2101/02 (20130101) C07C 2101/08 (20130101) C07C 2101/14 (20130101) C07C 2101/18 (20130101) Heterocyclic Compounds C07D 215/38 (20130101) C07D 215/40 (20130101) C07D 257/04 (20130101) C07D 295/26 (20130101) C07D 295/096 (20130101) C07D 333/34 (20130101) C07D 333/62 (20130101) C07D 403/12 (20130101) C07D 409/12 (20130101)
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09486429 — Therapeutic methods employing nitric oxide precursors

US 09486429	Summar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Marshall L. Summar (Brentwood, Tennessee); Brian W. Christman (Nashville, Tennessee); Frederick E. Barr (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Marshall L. Summar (Brentwood, Tennessee); Brian W. Christman (Nashville, Tennessee); Frederick E. Barr (Nashville, Tennessee)
ABSTRACT	Isolated polynucleotide molecules and peptides encoded by these molecules are used in the analysis of human carbamyl phosphate synthetase I phenotypes, as well as in diagnostic and therapeutic applications, relating to a human carbamyl phosphate synthetase I polymorphism. By analyzing genomic DNA or amplified genomic DNA, or amplified cDNA derived from mRNA, it is possible to type a human carbamyl phosphate synthetase I with regard to the human carbamyl phosphate synthetase I polymorphism, for example, in the context of diagnosing and treating hepatic veno-occlusive disease (HVOD) associated with bone marrow transplants.
FILED	Tuesday, February 24, 2004
APPL NO	10/785374
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/05 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) A61K 31/198 (20130101) Original (OR) Class A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101)
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09486434 — Method for delivery and use of isothiocyanates for prophylaxis and/or therapy of bladder cancer

US 09486434	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Yuesheng Zhang (Orchard Park, New York); Arup Bhattacharya (Buffalo, New York); Li Tang (Lancaster, New York); Yun Li (Orchard Park, New York); Joseph D. Paonessa (Niagara Falls, New York); Feng Geng (Columbus, Ohio); Yi Ding (Buffalo, New York)
ASSIGNEE(S)	Health Research Inc. (Buffalo, New York)
INVENTOR(S)	Yuesheng Zhang (Orchard Park, New York); Arup Bhattacharya (Buffalo, New York); Li Tang (Lancaster, New York); Yun Li (Orchard Park, New York); Joseph D. Paonessa (Niagara Falls, New York); Feng Geng (Columbus, Ohio); Yi Ding (Buffalo, New York)
ABSTRACT	Provided is a composition that contains a mixture of broccoli seed and mustard seed. Before mixing the broccoli seed with the mustard seed, the broccoli seed is subjected to baking and a pressurized heat treatment. The broccoli seed is baked at a temperature of at least 200 degrees Fahrenheit for at least 60 minutes, and is subjected to a pressurized heat treatment of at least 200 degrees Fahrenheit at a pressure of at least 10 pounds/square inch for at least 5 minutes. Also provided is a method for therapy and/or prophylaxis of bladder cancer in an individual. The method entails administering orally to the individual a composition that contains an isothiocyanate (ITC) or a derivative thereof such that the administration inhibits the growth and/or recurrence of bladder cancer. Nutraceutical compositions are also provided.
FILED	Tuesday, September 11, 2012
APPL NO	13/609531
ART UNIT	1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/26 (20130101) Original (OR) Class A61K 36/31 (20130101) A61K 2236/10 (20130101)
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09486442 — Methods for treating or preventing brain infections

US 09486442	Kim
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Kwang S. Kim (Baltimore, Maryland)
ABSTRACT	The invention is directed to methods of treating organ specific infections in a host organism by administering compounds that target host receptors and/or host cellular signaling molecules to prevent a pathogen from infecting the organ. For example, the administration of a compound to prevent a pathogen from crossing the blood-brain barrier to prevent a brain infection.
FILED	Tuesday, February 03, 2015
APPL NO	14/612773
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/41 (20130101) Original (OR) Class A61K 31/47 (20130101) A61K 31/121 (20130101) A61K 31/381 (20130101) A61K 31/404 (20130101)
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09486447 — Compositions and methods for controlling neuronal excitation

US 09486447	Peterson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute on Drug Abuse (NIDA) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Randall Peterson (Belmont, Massachusetts); Chung Yan J. Cheung (Cupertino, California); David Kokel (Somerville, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Randall Peterson (Belmont, Massachusetts); Chung Yan J. Cheung (Cupertino, California); David Kokel (Somerville, Massachusetts)
ABSTRACT	Embodiments of the technology described herein relate, at least in part, to methods of modulating the activity of a neuron by contacting the neuron with a photo-sensitive TrpA1 agonist and then illuminating the neuron with electromagnetic radiation. Also described herein are photo-sensitive TrpA1 agonists.
FILED	Wednesday, June 13, 2012
APPL NO	14/118988
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/4406 (20130101) A61K 31/4439 (20130101) Original (OR) Class A61K 41/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0622 (20130101) A61N 2005/0661 (20130101) A61N 2005/0663 (20130101)
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09486456 — Treatment of esophageal motility disorder using sepiapterin, tetrahydrobiopterin and derivatives thereof

US 09486456	Pasricha et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Pankaj J. Pasricha (Cupertino, California); Pandu R. R. Gangula (Nolensville, Tennessee)
ASSIGNEE(S)	The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	Pankaj J. Pasricha (Cupertino, California); Pandu R. R. Gangula (Nolensville, Tennessee)
ABSTRACT	The present invention discloses that diabetic rats showed a reduction in nitrergic relaxation of the gastric, impaired nNOS dimerization, decreased BH4 and GTPCH1 levels and thus, are more susceptible to develop diabetic gastroparesis. The use of tetrahydrobiopterin and its derivatives and sex steroid hormones as disclosed herein provides a novel strategy for therapeutic intervention of diabetic gastroparesis and any other gut-related diseases. Additionally, the present invention also discloses methods to determine risk of developing gastroparesis in an individual that are drawn to detecting variations in the activity and levels of GCH gene and in gene encoding sex steroid hormone receptor.
FILED	Thursday, March 06, 2014
APPL NO	14/199982
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/147777 (20150115)
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09486457 — Use of cinnabarinic acid as a modulator of immune responses in autoimmune disorders

US 09486457	Mold
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD)
APPLICANT(S)	Jeffrey Eron Mold (San Francisco, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jeffrey Eron Mold (San Francisco, California)
ABSTRACT	The present invention provides compounds and methods for preventing and treating an immune disorder in a subject.
FILED	Wednesday, February 23, 2011
APPL NO	13/579893
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/538 (20130101) Original (OR) Class
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09486470 — Compositions including triciribine and one or more platinum compounds and methods of use thereof

US 09486470	Cheng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	University of South Florida (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Jin Q. Cheng (Tampa, Florida); Said M. Sebti (Tampa, Florida)
ABSTRACT	This application encompasses combination therapies including triciribine and related compounds and one or more platinum compounds and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.
FILED	Friday, August 21, 2015
APPL NO	14/832417
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/282 (20130101) A61K 31/555 (20130101) A61K 31/706 (20130101) A61K 31/7064 (20130101) Original (OR) Class A61K 31/7076 (20130101) A61K 33/24 (20130101) A61K 39/39558 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57496 (20130101) G01N 2333/91205 (20130101)
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09486502 — Methods of administering interferon gamma to absorb fluid from the subretinal space

US 09486502	Li et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Rong Li (Rockville, Maryland); Sheldon S. Miller (Bethesda, Maryland); Arvydas Maminishkis (Washington, District of Columbia)
ABSTRACT	Particular aspects of the invention provide methods for decreasing the amount of fluid present in the subretinal space of the eye by administering interferon gamma to the basolateral side of the retinal pigment epithelium. Adverse ocular conditions associated with the accumulation of fluid in the subretinal space can be treated by administering an amount of interferon gamma to the basolateral side of the retinal pigment epithelium effective to remove excess fluid from the subretinal space.
FILED	Monday, April 14, 2014
APPL NO	14/252489
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) A61F 9/0026 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/217 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101)
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09486508 — Blood substitute composition and method of use

US 09486508	Lanza et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Washington University (St. Louis, Missouri)
ASSIGNEE(S)	WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S)	Gregory M. Lanza (St. Louis, Missouri); Dipanjan Pan (St. Louis, Missouri); Allan Doctor (St. Louis, Missouri); Philip C. Spinella (St. Louis, Missouri)
ABSTRACT	The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
FILED	Monday, November 02, 2015
APPL NO	14/930396
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0026 (20130101) A61K 9/51 (20130101) A61K 9/107 (20130101) A61K 38/42 (20130101) Original (OR) Class A61K 38/42 (20130101) A61K 38/063 (20130101) A61K 38/063 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101)
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09486518 — Membrane proximal region of HIV GP41 anchored to the lipid layer of a virus-like particle vaccine

US 09486518	Berkower
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Ira Berkower (Washington, District of Columbia)
ABSTRACT	Disclosed herein are isolated immunogens including variant hepatitis B surface antigens (HBsAgs). In an example, a variant HBsAg includes a HBsAg with one or more transmembrane domains of the HBsAg replaced with a gp41 antigenic insert. The antigenic insert can include an antigenic polypeptide fragment of gp41 including the membrane proximal region of gp41 and a transmembrane membrane region of gp41. The replacement of a membrane spanning domain of HBsAg with a membrane spanning domain of gp41 anchors gp41 into HBsAg in virtually the identical orientation as on HIV virions and correctly orients the nearby MPR on the lipid layer. Thus, the disclosed variant HBsAgs display the neutralization-sensitive MPR in association with a lipid layer, while presenting it at the most immunogenic site on HBsAg. Also disclosed are uses of these variant HBsAgs, and nucleic acids encoding variant HBsAgs, such as to induce an immune response to HIV-1.
FILED	Monday, March 09, 2015
APPL NO	14/642233
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 39/292 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/57 (20130101) A61K 2039/64 (20130101) A61K 2039/545 (20130101) A61K 2039/645 (20130101) A61K 2039/5256 (20130101) A61K 2039/5258 (20130101) A61K 2039/55505 (20130101) A61K 2039/55561 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2730/10122 (20130101) C12N 2730/10134 (20130101) C12N 2740/15022 (20130101) C12N 2740/15034 (20130101) C12N 2740/16134 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101)
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09486521 — Therapeutic applications targeting SARM1

US 09486521	Freeman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	UNIVERSITY OF MASSACHUSETTS (Shrewsbury, Massachusetts); UNIVERSITY OF MIAMI (Miami, Florida)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts); University of Miami (Miami, Florida)
INVENTOR(S)	Marc Freeman (Barre, Massachusetts); Stephan Zuchner (Pinecrest, Florida)
ABSTRACT	The present disclosure provides methods for reducing axonal and/or synaptic degradation in neurons by modulating sterile α/Armadillo/Toll-Interleukin receptor homology domain protein (SARM) activity and/or expression.
FILED	Friday, November 22, 2013
APPL NO	14/087206
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 38/00 (20130101) A61K 39/3955 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/5058 (20130101) G01N 33/6896 (20130101) G01N 2500/04 (20130101) G01N 2800/2814 (20130101) G01N 2800/2835 (20130101)
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09486522 — Compositions including triciribine and trastuzumab and methods of use thereof

US 09486522	Cheng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	University of South Florida (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Jin Q. Cheng (Tampa, Florida); Said M. Sebti (Tampa, Florida)
ABSTRACT	This application relates to combination therapies including triciribine and related compounds and trastuzumab or a salt thereof and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.
FILED	Tuesday, October 13, 2015
APPL NO	14/881777
ART UNIT	1673 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/7064 (20130101) A61K 31/7064 (20130101) A61K 33/24 (20130101) A61K 39/39533 (20130101) A61K 39/39558 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/32 (20130101) C07K 2317/73 (20130101)
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09486525 — Anti-neoplastic compositions comprising extracts of black cohosh

US 09486525	Einbond et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Linda Saxe Einbond (Crestwood, New York); I. Bernard Weinstein (New York, New York)
ASSIGNEE(S)	The Research Foundation of the City University of New York (New York, New York)
INVENTOR(S)	Linda Saxe Einbond (Crestwood, New York); I. Bernard Weinstein (New York, New York)
ABSTRACT	The present invention provides a composition for use in treating or preventing neoplasia, comprising an effective actein. The present invention also provides a composition for use in treating or preventing neoplasia, comprising an effective anti-neoplastic amount of an ethyl acetate extract of black cohosh. The present invention further provides a combination of anti-neoplastic agents, comprising an effective anti-neoplastic amount of an ethyl acetate extract of black cohosh and an effective anti-neoplastic amount of at least one additional chemopreventive or chemotherapeutic agent. Methods for treating and preventing neoplasia are also provided.
FILED	Friday, August 12, 2011
APPL NO	13/208962
ART UNIT	1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 36/71 (20130101) A61K 36/71 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09486533 — Pharmaceutical compositions for high-capacity targeted delivery

US 09486533	Gmeiner
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S)	William H. Gmeiner (Yadkinville, North Carolina)
ABSTRACT	Provided herein are aptamers and pharmaceutical compositions comprising the same. In some embodiments, the aptamer selectively binds a protein of interest such as an extracellular receptor protein of interest (e.g., a cancer cell extracellular receptor protein, which may be differentially expressed in some embodiments). In some embodiments, the aptamer is directly linked by covalent bonding (e.g., via a geminal diamine linkage) to from 2 to 10 toxin compounds. Also provided herein is a method of selecting an aptamer that specifically binds to a protein expressed by a cell of interest, wherein in some embodiments the aptamer comprises at least one binding site for one or more active compounds. In some embodiments, primer regions flanking the variable region of the aptamers in the pool contains from 1 to 10 mismatches with respect to said forward or reverse primer.
FILED	Friday, September 26, 2014
APPL NO	14/498444
ART UNIT	1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/704 (20130101) A61K 47/48092 (20130101) Original (OR) Class
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09486535 — Methods of making and using nanostructures

US 09486535	Wagner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (St. Paul, Minnesota)
ASSIGNEE(S)	TYCHON BIOSCIENCE, LLC (Minneapolis, Minnesota)
INVENTOR(S)	Carston R. Wagner (St. Paul, Minnesota); Jae Chul Lee (Dublin, Ohio); Sidath C. Kumarapperuma (Roseville, Minnesota)
ABSTRACT	The invention provides methods for attaching drugs, dyes or radiolabels to bis-MTX. This method can be used to prepare bis-MTX analogs that can be used to deliver agents, such as nanoparticles, drugs, dyes or radiolabels, to cells.
FILED	Friday, January 18, 2013
APPL NO	14/373209
ART UNIT	1672 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 33/24 (20130101) A61K 47/481 (20130101) A61K 47/48061 (20130101) A61K 47/48092 (20130101) A61K 47/48561 (20130101) Original (OR) Class A61K 47/48746 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Heterocyclic Compounds C07D 475/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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09486539 — Nipah virus envelope pseudotyped lentiviruses and methods of their use

US 09486539	Lee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Benhur Lee (Los Angeles, California); Karina Palomares (Los Angeles, California); Olivier Pernet (Los Angeles, California)
ABSTRACT	The present invention relates to lentiviral particles which have been pseudotyped with Nipah virus (NiV) fusion (F) and attachment (G) glycoproteins (NiVpp-F/G). Additionally, the present invention relates to truncated NiV-F glycoproteins useful in producing such NiVpp lentiviral particles, as well as to additional variant peptides which enhance activity. Further, the present invention relates to methods of using such lentiviral particles or sequences, for example in the treatment of cancer or CNS disorders.
FILED	Friday, March 15, 2013
APPL NO	14/387371
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 48/00 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2740/15032 (20130101) C12N 2740/15041 (20130101) C12N 2740/15043 (20130101) C12N 2760/18222 (20130101) C12N 2760/18232 (20130101) C12N 2760/18234 (20130101) C12N 2760/18241 (20130101) C12N 2760/18245 (20130101) C12N 2810/6027 (20130101)
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09486541 — Detecting and treating dementia

US 09486541	Hutton et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota); VIB VZW (Ghent, Belgium); Universiteit Antwerpen (Antwerpen, Belgium); The University of British Columbia (Vancouver, Canada); The University of Manchester (Manchester, United Kingdom)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota); VIB VZW (Ghent, Belgium); Universteit Antwerpen (Antwerp, Belgium); The University of British Columbia (Vancouver, Canada); The University of Manchester (Manchester, United Kingdom)
INVENTOR(S)	Michael L. Hutton (Newton, Massachusetts); Matthew Charles Baker (Jacksonville, Florida); Jennifer Mae Gass (Atlantic Beach, Florida); Rosa Rademakers (Ponte Vedra, Florida); Jason Eriksen (Houston, Texas); Stuart M. Pickering-Brown (Derbyshire, United Kingdom); Ian Reid Alexander Mackenzie (Vancouver, Canada); Howard Feldman (Vancouver, Canada); Samir Kumar-Singh (Edegem, Belgium); Christine Van Broeckhoven (Edegem, Belgium); Marc Cruts (Antwerpen, Belgium); Ashley Diane Cannon (Jacksonville, Florida)
ABSTRACT	This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents that can be used to increase PGRN polypeptide levels in mammals.
FILED	Monday, July 01, 2013
APPL NO	13/932727
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Peptides C07K 14/435 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6883 (20130101) C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/172 (20130101)
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09486619 — Interconnect devices, systems, and methods for bridging electronic devices

US 09486619	Tyler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Dustin Tyler (Highland Heights, Ohio); Yueshuo Xu (Shaker Heights, Ohio); Allison Hess-Dunning (Cleveland Heights, Ohio); Christian Zorman (Euclid, Ohio)
ABSTRACT	One aspect of the present disclosure can include an interconnect system for bridging electrical contacts. The system can include a first electrical contact, a second electrical contact, and an interconnect device that is coupled to and extends between the first and second electrical contacts. The interconnect device can include a flexible bridge and a non-linear conductive transmission line. The flexible bridge can have a length and an outer surface. The non-linear conductive transmission line can extend along, and encircle at least a portion of, the length of the bridge such that the non-linear conductive transmission line electrically connects the first electrical contact with the second electrical contact.
FILED	Wednesday, February 11, 2015
APPL NO	14/619560
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) Original (OR) Class A61N 1/3605 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/562 (20130101) H01R 2201/12 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/148 (20130101)
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09487476 — Catechol diethers as potent anti-HIV agents

US 09487476	Jorgensen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S)	YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S)	William L. Jorgensen (Deep River, Connecticut); Karen S. Anderson (Guilford, Connecticut)
ABSTRACT	The present invention is directed to novel catechol diether compounds, pharmaceutical compositions therefrom and methods for inhibiting reverse transcriptase and treating HIV infections, especially included drug resistant strains of HIV 1 and 2 and/or secondary disease states and/or conditions which occur as a consequence of HIV infection.
FILED	Friday, October 12, 2012
APPL NO	14/348952
ART UNIT	1672 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/277 (20130101) A61K 31/505 (20130101) A61K 31/513 (20130101) A61K 31/536 (20130101) A61K 31/4409 (20130101) A61K 31/4412 (20130101) A61K 31/5025 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 255/54 (20130101) Original (OR) Class Heterocyclic Compounds C07D 213/57 (20130101) C07D 213/69 (20130101) C07D 239/10 (20130101) C07D 239/54 (20130101) C07D 239/553 (20130101) C07D 251/42 (20130101) C07D 405/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101)
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09487495 — Carbamate compounds and of making and using same

US 09487495	Cisar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	ABIDE THERAPEUTICS, INC. (San Diego, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S)	THE SCRIPTS RESEARCH INSTITUTE (La Jolla, California); ABIDE THERAPEUTICS (San Diego, California)
INVENTOR(S)	Justin S. Cisar (San Diego, California); Cheryl A. Grice (Encinitas, California); Todd K. Jones (Solana Beach, California); Micah J. Niphakis (San Diego, California); Jae Won Chang (San Diego, California); Kenneth M. Lum (San Diego, California); Benjamin F. Cravatt (La Jolla, California)
ABSTRACT	This disclosure provides compounds having the structure: wherein L³, R⁷, R^dand p are defined herein, which are modulators of MAGL and/or ABHD6. Further provided is the use of these compounds as medicinal agents, processes for their preparation, and pharmaceutical compositions that include the disclosed compounds. The disclosure also provides a method of treating a patient in need thereof, where the patient is suffering from indications such as pain, solid tumor cancer and/or obesity comprising administering a disclosed compound or composition.
FILED	Monday, January 07, 2013
APPL NO	14/369982
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 271/10 (20130101) C07C 271/12 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 207/09 (20130101) C07D 207/14 (20130101) C07D 213/40 (20130101) C07D 213/55 (20130101) C07D 215/42 (20130101) C07D 231/12 (20130101) C07D 231/16 (20130101) C07D 231/56 (20130101) C07D 241/04 (20130101) C07D 261/08 (20130101) C07D 263/32 (20130101) C07D 271/06 (20130101) C07D 295/26 (20130101) Original (OR) Class C07D 295/205 (20130101) C07D 307/79 (20130101) C07D 317/46 (20130101) C07D 317/58 (20130101) C07D 401/04 (20130101) C07D 405/14 (20130101) C07D 407/06 (20130101) C07D 413/06 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 487/04 (20130101) C07D 491/107 (20130101)
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09487500 — Compounds and compositions thereof

US 09487500	Deokar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Inhibikase Therapeutics, Inc. (Atlanta, Georgia); Sphaera Pharma Pte. Ltd. (Singapore, Singapore)
ASSIGNEE(S)	INHIBIKASE THERAPEUTICS, INC. (Atlanta, Georgia)
INVENTOR(S)	Rhushikesh C. Deokar (Imt Manesar, India); Sundeep H. Dugar (San Jose, California); Dinesh Mahajan (Imt Manesar, India); Milton H. Werner (Marietta, Georgia)
ABSTRACT	Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.
FILED	Friday, October 04, 2013
APPL NO	14/046682
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/095 (20130101) A61K 31/506 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 309/04 (20130101) Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class
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09487522 — SSH-2 (slingshot-2) inhibitors and methods for making and using them

US 09487522	Haga et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Science Foundation (NSF) Office of The Director (OD) Office of International Science and Engineering (OISE)
APPLICANT(S)	Jason H. Haga (San Diego, California); Shu Chien (La Jolla, California); Matt Mui (La Jolla, California); Marshall J. Levesque (Philadelphia, Pennsylvania); Phillip D. Pham (San Francisco, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jason H. Haga (San Diego, California); Shu Chien (La Jolla, California); Matt Mui (La Jolla, California); Marshall J. Levesque (Philadelphia, Pennsylvania); Phillip D. Pham (San Francisco, California)
ABSTRACT	In alternative embodiments, the invention provides compositions that inhibit the polypeptide SSH-2, or SlingSHot-2, a phosphatase enzyme that regulates actin filaments, and methods for making and using them, including methods comprising administering compositions of the invention to regulate or modify actin filament polymerization by inhibiting SSH-2, where in one embodiment compositions of the invention slow or inhibit F-actin depolymerization and severing. In alternative embodiments, compositions and methods of the invention are used to slow or inhibit cell motility and/or internal remodeling. In alternative embodiments, compositions and methods of the invention are used to slow or inhibit, or reverse, or ameliorate the progression of a cancer or a metastasis or other uncontrolled or unregulated cell growth, and/or Alzheimer's disease.
FILED	Thursday, March 15, 2012
APPL NO	14/005653
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 31/192 (20130101) A61K 31/365 (20130101) A61K 31/422 (20130101) A61K 31/451 (20130101) A61K 31/497 (20130101) A61K 31/502 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4025 (20130101) Acyclic or Carbocyclic Compounds C07C 311/17 (20130101) Heterocyclic Compounds C07D 211/96 (20130101) C07D 237/32 (20130101) C07D 307/90 (20130101) C07D 417/06 (20130101) C07D 487/04 (20130101) Original (OR) Class
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09487530 — Transient protection of normal cells during chemotherapy

US 09487530	Strum et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	G1 Therapeutics, Inc. (Chapel Hill, North Carolina)
ASSIGNEE(S)	G1 Therapeutics, Inc. (Chapel Hill, North Carolina)
INVENTOR(S)	Jay Copeland Strum (Hillsborough, North Carolina); John Emerson Bisi (Apex, North Carolina); Patrick Joseph Roberts (Durham, North Carolina); Francis Xavier Tavares (Durham, North Carolina)
ABSTRACT	This invention is in the area of improved compounds, compositions and methods of transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC) as well as renal cells, from damage associated with DNA damaging chemotherapeutic agents. In one aspect, improved protection of healthy cells is disclosed using disclosed compounds that act as highly selective and short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects undergoing DNA damaging chemotherapeutic regimens for the treatment of proliferative disorders.
FILED	Friday, March 14, 2014
APPL NO	14/212430
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/527 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 487/14 (20130101) Original (OR) Class
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09487534 — Modulators of virus assembly as antiviral agents

US 09487534	Zlotnick et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Adam Zlotnick (Bloomington, Indiana); M. G. Finn (San Diego, California)
ASSIGNEE(S)	Scripps Research Institute, A Not-for-Profit Public Benefit Corporation of California (La Jolla, California); Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S)	Adam Zlotnick (Bloomington, Indiana); M. G. Finn (San Diego, California)
ABSTRACT	In addition to containing and protecting the viral genome, the capsid (protein shell) of hepatitis B virus (HBV) plays critical roles in the viral life cycle including regulation of intracellular trafficking and nucleic acid metabolism. Substituted pyrimidine modulators of the assembly of the HBV capsid structure and methods for their use are described.
FILED	Thursday, August 02, 2012
APPL NO	14/236428
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) Heterocyclic Compounds C07D 239/20 (20130101) C07D 239/22 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 417/04 (20130101) C07D 471/04 (20130101) C07D 491/10 (20130101) C07D 491/113 (20130101) Original (OR) Class C07D 493/10 (20130101)
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09487536 — Melampomagnolide B derivatives

US 09487536	Bommagani et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Board of Trustees of the University of Arkansas (Little Rock, Arkansas); The Regents of the University of Colorado (Aurora, Colorado)
ASSIGNEE(S)	BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas); REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
INVENTOR(S)	Shobanbabu Bommagani (Little Rock, Arkansas); Peter Crooks (Little Rock, Arkansas); Narsimha Reddy Penthala (Little Rock, Arkansas); Venumadhav Janganati (Little Rock, Arkansas); Craig T. Jordan (Aurora, Colorado); Jessica Ponder (Aurora, Colorado)
ABSTRACT	The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, thiocarbamates, ester and amide derivatives of MMB. These derivatives are useful for treating cancer in humans.
FILED	Wednesday, April 01, 2015
APPL NO	14/676537
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 493/04 (20130101) Original (OR) Class
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09487538 — Two-carbon linked artemisinin-derived trioxane dimers

US 09487538	Posner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Gary H. Posner (Baltimore, Maryland); Bryan T. Mott (Baltimore, Maryland)
ABSTRACT	Two-carbon linked artemisinin-derived trioxane dimers and methods of their use for treating subjects infected with malaria or other parasitic infectious diseases including, but not limited to, toxoplasmic infection; subjects afflicted with psychiatric conditions associated with toxoplasmic infection; and subjects afflicted with cancer.
FILED	Wednesday, January 22, 2014
APPL NO	14/761699
ART UNIT	1672 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) A61K 31/683 (20130101) A61K 31/4433 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 321/02 (20130101) C07D 493/18 (20130101) Original (OR) Class C07D 519/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65527 (20130101)
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09487541 — Fused tricyclic ether carbamates and their use

US 09487541	Ghosh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana); NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (Kumamoto, Japan)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana); National University Corporation Kumamoto University (Kumamoto, Japan)
INVENTOR(S)	Arun K. Ghosh (West Lafayette, Indiana); Chun-Xiao Xu (College Station, Texas); Hiroaki Mitsuya (Kumamoto, Japan); Garth Parham (Largo, Florida)
ABSTRACT	Tricylic ether carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are describes. Methods of using the disclosed compounds for treating patients infected with HIV are also described.
FILED	Tuesday, October 08, 2013
APPL NO	14/048487
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 493/04 (20130101) C07D 493/14 (20130101) C07D 495/14 (20130101) Original (OR) Class
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09487551 — Small molecule compounds that control mammal-pathogenic nematodes

US 09487551	Choe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Andrea Choe (Los Angeles, California); Paul W. Sternberg (Pasadena, California); Frank C. Schroeder (Ithaca, New York); Stephan H. Von Reuss (Jena, Germany); Raffi V. Aroian (San Diego, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California); Boyce Thompson Institute for Plant Research (Ithaca, New York); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Andrea Choe (Los Angeles, California); Paul W. Sternberg (Pasadena, California); Frank C. Schroeder (Ithaca, New York); Stephan H. Von Reuss (Jena, Germany); Raffi V. Aroian (San Diego, California)
ABSTRACT	The present invention relates to methods of modifying nematode behavior using certain isolated modulator compounds. Also disclosed are methods of promoting or inhibiting reproduction in a nematode population, methods of promoting or inhibiting nematode aggregation at a mammal, and methods of treating or preventing parasite infection of a mammal.
FILED	Wednesday, August 08, 2012
APPL NO	14/237800
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/16 (20130101) A01N 43/38 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) A61K 31/7028 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/04 (20130101) Original (OR) Class C07H 15/08 (20130101) C07H 15/10 (20130101) C07H 15/18 (20130101) C07H 15/26 (20130101)
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09487563 — Virus-like particles and methods of use

US 09487563	Nabel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center (VRC)
APPLICANT(S)	Gary J. Nabel (Washington, District of Columbia); Srinivas Rao (Columbia, Maryland); Wataru Akahata (Kensington, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Gary J. Nabel (Washington, District of Columbia); Srinivas Rao (Columbia, Maryland); Wataru Akahata (Kensington, Maryland)
ABSTRACT	The invention features modified alphavirus or flavivirus virus-like particles (VLPs). The invention provides methods, compositions, and kits featuring the modified VLPs. The invention also features methods for enhancing production of modified VLPs for use in the prevention or treatment of alphavirus and flavivirus-mediated diseases. The invention also provides methods for delivering agents to a cell using the modified VLPs.
FILED	Tuesday, January 31, 2012
APPL NO	13/982986
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/53 (20130101) A61K 2039/5258 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/36123 (20130101) C12N 2770/36134 (20130101) C12N 2770/36151 (20130101)
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09487572 — Non-standard insulin analogues

US 09487572	Weiss
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Michael A. Weiss (Moreland Hills, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Michael A. Weiss (Moreland Hills, Ohio)
ABSTRACT	An insulin analog comprises a B-chain polypeptide containing a cyclohexanylalanine substitution at position B24 and optionally containing additional amino-acid substitutions at positions A8, B28, and/or B29. A proinsulin analog or single-chain insulin analog containing a B domain containing a cyclohexanylalanine substitution at position B24 and optionally containing additional amino-acid substitutions at positions A8, B28, and/or B29. The analog may be an analog of a mammalian insulin, such as human insulin. A nucleic acid encoding such an insulin analog is also provided. A method of lowering the blood sugar of a patient comprises administering a physiologically effective amount of the insulin analog or a physiologically acceptable salt thereof to a patient. A method of semi-synthesis using an unprotected octapeptide by means of modification of an endogenous tryptic site by non-standard amino-acid substitutions.
FILED	Friday, July 13, 2012
APPL NO	14/232496
ART UNIT	1675 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Peptides C07K 14/62 (20130101) Original (OR) Class
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09487573 — Murine anti-NY-ESO-1 T cell receptors

US 09487573	Parkhurst et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Maria R. Parkhurst (Ellicott City, Maryland); Richard A. Morgan (Columbia, Maryland); Steven A. Rosenberg (Potomac, Maryland); Shannon Faith Rosati (Richmond, Virginia)
ABSTRACT	The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for NY-ESO-1. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a mammal and a method of treating or preventing cancer in a mammal using the inventive TCRs or related materials.
FILED	Wednesday, May 22, 2013
APPL NO	14/401893
ART UNIT	1675 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 16/18 (20130101) C07K 16/2809 (20130101) C07K 2317/20 (20130101) C07K 2317/21 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/7051 (20130101)
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09487577 — Anti-glucosaminidase passive immunization for Staphylococcus aureus infections

US 09487577	Schwarz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	UNIVERSITY OF ROCHESTER (Rochester, New York)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Edward M. Schwarz (Rochester, New York); Mark A. Sullivan (Fairport, New York); John L. Daiss (Rochester, New York)
ABSTRACT	The present invention is directed to a monoclonal antibody that binds specifically to a Staphylococcus aureus glucosaminidase and inhibits in vivo growth of S. aureus. Also disclosed are monoclonal antibody binding portions, recombinant or hybridoma cell lines, pharmaceutical compositions containing the monoclonal antibody or binding portions thereof, and methods of treating S. aureus infection and osteomyelitis, and methods for introducing an orthopedic implant into a patient using the monoclonal antibody, binding portion, or pharmaceutical composition of the present invention.
FILED	Tuesday, October 30, 2012
APPL NO	14/355524
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1271 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101)
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09487579 — Methods and compositions for modulation of blood-neural barrier

US 09487579	Eriksson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Ludwig Institute for Cancer Research (New York, New York)
ASSIGNEE(S)	LUDWIG INSTITUTE FOR CANCER RESEARCH (New York, New York); UNIVERSITY OF MARYLAND (Baltimore, Maryland); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Ulf Eriksson (Stockholm, Sweden); Linda Fredriksson (Hagersten, Sweden); Daniel Lawrence (Ann Arbor, Michigan); Enming Su (Ann Arbor, Michigan); Manuel Yepes (Atlanta, Georgia); Dudley Strickland (Brookville, Maryland)
ABSTRACT	Methods and compositions for modulating blood-neural barrier (BNB) for the treatment of CNS conditions such as edema, and for increased drug delivery efficacy across the BNB. The present invention further relates to improved tPA treatment of ischemic cerebrovascular and related diseases in combination with antagonism of the PDGF signaling pathway. The inventive method and composition is particularly suitable for conjunctive therapy of ischemic stroke using tPA and an anti-PDGF-C antagonist or an anti-PDGFR-α antagonist.
FILED	Tuesday, May 20, 2014
APPL NO	14/282808
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39533 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/22 (20130101) Original (OR) Class C07K 2316/96 (20130101) C07K 2317/76 (20130101)
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09487745 — Micro-patterned plate composed of an array of releasable elements surrounded with solid or gel walls

US 09487745	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Yuli Wang (Cary, North Carolina); Nancy Allbritton (Chapel Hill, North Carolina)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Yuli Wang (Cary, North Carolina); Nancy Allbritton (Chapel Hill, North Carolina)
ABSTRACT	A micro-patterned plate composed of an array of releasable elements surrounded by a gel or solid wall and methods of manufacture of the micropatterned plate. The surface properties of walls can be tailored if needed to be repellent or attracting to proteins. The walls can also inhibit cell attachment. The walls enable cells or other materials to be localized to the tops of the releasable elements. The individual element in the array of releasable elements can be released from the array by a mechanical force.
FILED	Friday, July 25, 2008
APPL NO	12/670365
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 1/20 (20130101) Original (OR) Class C12M 3/00 (20130101) C12M 23/22 (20130101) C12M 23/44 (20130101) C12M 25/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/02 (20130101) C12N 5/00 (20130101) C12N 11/02 (20130101) C12N 11/14 (20130101)
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09487750 — Methods and compositions for growth of cells and embryonic tissue on a synthetic polymer matrix

US 09487750	Smith et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Gary D. Smith (Ann Arbor, Michigan); Joerg Lahann (Ann Arbor, Michigan); Himabindu Nandivada (Ann Arbor, Michigan); Thomas Eyster (Ann Arbor, Michigan); Luis Villa Diaz (Dearborn, Michigan); Paul Krebsbach (Ann Arbor, Michigan)
ABSTRACT	The present invention provides methods and compositions for establishing and maintaining growth of cells and embryonic tissue on a synthetic polymer matrix. For example, the present invention provides synthetic growth matrices for stem cells, gametes, mature differentiated cells, and embryonic tissue (e.g., blastomeres, embryos, and embryoid bodies). In certain embodiments, the cells are capable of going through multiple passages while remaining in an undifferentiated state as a result of the synthetic polymer matrix.
FILED	Thursday, May 22, 2014
APPL NO	14/285259
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/20 (20130101) C08F 220/38 (20130101) C08F 2220/606 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0606 (20130101) Original (OR) Class C12N 2533/30 (20130101) C12N 2533/40 (20130101)
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09487751 — Method to isolate, identify, and use embryonic stem cells directed to forebrain interneuron fate

US 09487751	Anderson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Stewart A. Anderson (New York, New York); Asif Maroof (New York, New York); Lorenz Studer (New York, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York); SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York)
INVENTOR(S)	Stewart A. Anderson (New York, New York); Asif Maroof (New York, New York); Lorenz Studer (New York, New York)
ABSTRACT	The present invention relates to methods of isolating a purified or enriched population of cortical or striatal immature interneuron progenitor cells and the isolated purified or enriched population of immature interneuron progenitor cells. Methods of treating a condition mediated by a loss or deficiency of interneuron function using the purified or enriched population of immature interneuron progenitor cells are also disclosed.
FILED	Wednesday, June 02, 2010
APPL NO	13/376039
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2500/44 (20130101) C12N 2501/15 (20130101) C12N 2501/41 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2510/00 (20130101) C12N 2533/90 (20130101)
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09487754 — Derivation of fibrochondrocytes from progenitor cells

US 09487754	Mao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Jeremy J. Mao (Closter, New Jersey); Chang Hun Lee (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Jeremy J. Mao (Closter, New Jersey); Chang Hun Lee (New York, New York)
ABSTRACT	Provided herein are compositions and methods for forming fibrochondrocytes or fibrochondrocyte-like cells from progenitor cells, such as mesenchymal stem cells. One aspect provides a fibrochondrocyte culture medium including CTGF and TGFβ3, optionally encapsulated by microspheres having different release profiles. Another aspect provides a method for forming fibrochondrocytes or fibrochondrocyte-like cells from progenitor cells by culturing with CTGF and TGFβ3.
FILED	Monday, October 03, 2011
APPL NO	13/877260
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2430/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0655 (20130101) Original (OR) Class C12N 2501/10 (20130101) C12N 2501/15 (20130101) C12N 2531/00 (20130101) C12N 2533/40 (20130101)
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09487757 — Glial cells and oligodendrocytes produced by reprogramming somatic cells with Sox10, Olig2 and Nkx6.2

US 09487757	Tesar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Paul J. Tesar (Wickliffe, Ohio); Robert H. Miller (Cleveland Heights, Ohio); Fadi J. Najm (University Heights, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Paul J. Tesar (Wickliffe, Ohio); Robert H. Miller (Cleveland Heights, Ohio); Fadi J. Najm (University Heights, Ohio)
ABSTRACT	The present invention relates to the reprogramming of differentiated somatic cells, such as those differentiated cells that arise from embryonic mesoderm, into glial cells. Glial cells produced from this reprogramming are functionally equivalent to glial cells that arise from ectodermal origins.
FILED	Tuesday, October 25, 2011
APPL NO	13/280562
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2501/41 (20130101) C12N 2501/60 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2506/1307 (20130101)
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09487763 — Nonribosomal peptide synthetases

US 09487763	Sherman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) Fogarty International Center (FIC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	David H. Sherman (Ann Arbor, Michigan); Michael Marie Kaufman-Schofield (Ann Arbor, Michigan); Sunit Jain (Ann Arbor, Michigan); Gregory Dick (Ann Arbor, Michigan)
ABSTRACT	The present disclosure is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS)-derived drug and analogs thereof. The invention provides polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS-derived drug, the polypeptides encoded by such polynucleotides, expression vectors comprising the polynucleotides, host cells comprising the polynucleotides or expression vectors, and kits comprising a host cell. Also provided is a method for the production of ET-743, the NRPS-derived drug.
FILED	Friday, May 15, 2015
APPL NO	14/713662
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0051 (20130101) C12N 9/88 (20130101) C12N 9/93 (20130101) C12N 9/0095 (20130101) C12N 9/1007 (20130101) C12N 9/1025 (20130101) C12N 9/1029 (20130101) Original (OR) Class C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/185 (20130101) Enzymes C12Y 108/01007 (20130101) C12Y 118/01002 (20130101) C12Y 201/01 (20130101) C12Y 203/01 (20130101) C12Y 203/0104 (20130101) C12Y 203/01187 (20130101) C12Y 402/01001 (20130101) C12Y 402/01059 (20130101) C12Y 603/04015 (20130101)
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09487779 — siRNA-mediated gene silencing

US 09487779	Davidson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S)	University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S)	Beverly L. Davidson (Iowa City, Iowa); Henry Paulson (Iowa City, Iowa); Victor Miller (Iowa City, Iowa); Cynthia Gouvion (Iowa City, Iowa)
ABSTRACT	The present invention is directed to small interfering RNA molecules (siRNA) targeted against an allele of interest, and methods of using these siRNA molecules.
FILED	Thursday, June 05, 2014
APPL NO	14/297378
ART UNIT	1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/05 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/53 (20130101) C12N 2310/111 (20130101) C12N 2330/30 (20130101) C12N 2799/021 (20130101) C12N 2799/022 (20130101) Enzymes C12Y 302/01031 (20130101)
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09487785 — Multi-targeting short interfering RNAs

US 09487785	Rossi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	CITY OF HOPE (Duarte, California)
ASSIGNEE(S)	CITY OF HOPE (Duarte, California)
INVENTOR(S)	John J. Rossi (Azusa, California); Ola Snove, Jr. (Oslo, Norway); Ali Ehsani (West Covina, California); Pal Saetrom, Jr. (Trondheim, Norway); Britta Vallazza (Hagen, Germany); Jane Zhang (South El Monte, California); Lars Aagaard (Ry, Denmark)
ABSTRACT	The present invention relates to novel short interfering RNA (siRNA) molecules that are multi-targeted. More specifically, the present invention relates to siRNA molecules that target two or more sequences. In one embodiment, multi-targeting siRNA molecules are designed to incorporate features of siRNA molecules and features of micro-RNA (miRNA) molecules. In another embodiment, multi-targeting siRNA molecules are designed so that each strand is directed to separate targets.
FILED	Monday, December 22, 2014
APPL NO	14/579313
ART UNIT	1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1132 (20130101) C12N 15/1135 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/51 (20130101) C12N 2310/53 (20130101) C12N 2320/30 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/02 (20130101) Electric Digital Data Processing G06F 19/22 (20130101)
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09487787 — Method for regulating protein function in cells using synthetic small molecules

US 09487787	Wandless et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Thomas J. Wandless (Menlo Park, California); Laura Anne Banaszynski (New York, New York); Mari Iwamoto (Stanford, California); Lystranne Alysia Maynard (Silver Spring, Maryland); Ling-Chun Chen (Fremont, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Thomas J. Wandless (Menlo Park, California); Laura Anne Banaszynski (New York, New York); Mari Iwamoto (Stanford, California); Lystranne Alysia Maynard (Silver Spring, Maryland); Ling-Chun Chen (Fremont, California)
ABSTRACT	Methods and compositions for the rapid and reversible destabilizing of specific proteins using cell-permeable, synthetic molecules are described. Stability-affecting proteins, e.g., derived from FKBP and DHFR proteins are fused to a protein of interest and the presence or absence of the ligand is used to modulate the stability of the fusion protein.
FILED	Thursday, March 22, 2012
APPL NO	13/427432
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 2319/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class
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09487788 — E. coli plasmid DNA production

US 09487788	Williams et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	NATURE TECHNOLOGY CORPORATION (Lincoln, Nebraska)
ASSIGNEE(S)	Nature Technology Corporation (Lincoln, Nebraska)
INVENTOR(S)	James A. Williams (Lincoln, Nebraska); Aaron E. Carnes (Lincoln, Nebraska)
ABSTRACT	General methods and strains of bacteria are described that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined with flocculation mediated removal of cell debris and host nucleic acids achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.
FILED	Tuesday, February 03, 2015
APPL NO	14/612952
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/06 (20130101) C12N 15/64 (20130101) C12N 15/73 (20130101) Original (OR) Class C12N 15/1003 (20130101)
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09487789 — E. coli plasmid DNA production

US 09487789	Williams et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	NATURE TECHNOLOGY CORPORATION (Lincoln, Nebraska)
ASSIGNEE(S)	Nature Technology Corporation (Lincoln, Nebraska)
INVENTOR(S)	James A. Williams (Lincoln, Nebraska); Aaron E. Carnes (Lincoln, Nebraska)
ABSTRACT	General methods and strains of bacteria are described that dramatically simplify and streamline plasmid DNA production. In one preferred embodiment, endolysin mediated plasmid extraction combined with flocculation mediated removal of cell debris and host nucleic acids achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.
FILED	Tuesday, February 03, 2015
APPL NO	14/612960
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/06 (20130101) C12N 15/64 (20130101) C12N 15/73 (20130101) Original (OR) Class C12N 15/1003 (20130101)
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09487802 — Compositions and methods to treat latent viral infections

US 09487802	Quake et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
INVENTOR(S)	Stephen R. Quake (Palo Alto, California); Jianbin Wang (Palo Alto, California)
ABSTRACT	Viral infection is a persistent cause of human disease. Guided nuclease systems target the genomes of viral infections, rendering the viruses incapacitated.
FILED	Thursday, July 02, 2015
APPL NO	14/790748
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 15/1133 (20130101) C12N 2310/10 (20130101) C12N 2330/51 (20130101) C12N 2810/60 (20130101) Enzymes C12Y 301/00 (20130101)
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09487812 — Optical alignment deformation spectroscopy

US 09487812	Neeves et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Colorado School of Mines (Golden, Colorado)
ASSIGNEE(S)	Colorado School of Mines (Golden, Colorado)
INVENTOR(S)	Keith B. Neeves (Denver, Colorado); David W. M. Marr (Golden, Colorado); Kevin B. Roth (Golden, Colorado); Charles D. Eggleton (Baltimore, Maryland)
ABSTRACT	A microfluidic system, device, and method are disclosed. The microfluidic system may include a first microfluidic channel and a second microfluidic channel, each of which are carrying one or more objects. There is an intersection between the first and second microfluidic channels where one or more objects from the first microfluidic channel impact one or more objects from the second microfluidic channel under hydrodynamic forces. The impact causes the objects to deform and the deformation of objects can be analyzed to determine properties of the object.
FILED	Tuesday, February 19, 2013
APPL NO	13/770875
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0668 (20130101) B01L 2400/0463 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1484 (20130101) G01N 2015/1495 (20130101)
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09487828 — Methods for determining a nucleotide sequence contiguous to a known target nucleotide sequence

US 09487828	Iafrate et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Anthony John Iafrate (Newton, Massachusetts); Long Phi Le (Boston, Massachusetts); Zongli Zheng (Boston, Massachusetts)
ABSTRACT	The technology described herein is directed to methods of determining oligonucleotide sequences, e.g. by enriching target sequences prior to sequencing the sequences.
FILED	Monday, March 11, 2013
APPL NO	13/793564
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6855 (20130101) C12Q 1/6855 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2525/186 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2537/159 (20130101) C12Q 2537/159 (20130101) C12Q 2565/607 (20130101) C12Q 2565/607 (20130101)
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09487829 — Safe sequencing system

US 09487829	Vogelstein et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Isaac Kinde (Beaumont, California)
ABSTRACT	Error rates in massively parallel sequencing instruments are generally too high to allow confident identification of rare variants. An approach that can substantially increase the sensitivity of massively parallel sequencing instruments for this purpose, called “Safe-SeqS” for (Safe-Sequencing System) includes (i) assignment of a unique identifier (UID) to each template molecule; (ii) amplification of each uniquely tagged template molecule to create UID-families; and (iii) redundant sequencing of the amplification products. PCR fragments with the same UID are truly mutant (“super-mutants”) if ≧95% of them contain the identical mutation. We illustrate the utility of this approach for determining the fidelity of a polymerase, the accuracy of oligonucleotides synthesized in vitro, and the prevalence of mutations in the nuclear and mitochondrial genomes of normal cells.
FILED	Thursday, July 30, 2015
APPL NO	14/814030
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) C12Q 2600/158 (20130101)
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09487832 — Selective detection of neisseria meningitidis

US 09487832	Thomas
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC)
APPLICANT(S)	Jennifer Thomas (Atlanta, Georgia)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia)
INVENTOR(S)	Jennifer Thomas (Atlanta, Georgia)
ABSTRACT	A process for detecting Neisseria meningitidis nucleic acid in a sample is provided including producing an amplification product by amplifying Neisseria meningitidis nucleotide sequence of the sodC gene or mRNA using a forward primer of SEQ ID NO: 1, and a reverse primer of SEQ ID NO: 2, and detecting the amplification product to detect Neisseria meningitidis in the sample. Also provided are reagents and methods for detecting and distinguishing Neisseria meningitidis from other infectious agents. A kit is provided for detecting and quantifying Neisseria meningitidis in a sample.
FILED	Tuesday, October 11, 2011
APPL NO	13/816903
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class
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09487839 — Method for detecting single nucleotide polymorphisms

US 09487839	Arts et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Eric J. Arts (Cleveland Heights, Ohio); Matthew LaLonde (Cleveland Heights, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Eric J. Arts (Cleveland Heights, Ohio); Matthew LaLonde (Cleveland Heights, Ohio)
ABSTRACT	A method of detecting a single nucleotide polymorphism includes providing a first template polynucleotide, a second polynucleotide comprising a first and second sequence (complementary to a first portion of the first polynucleotide), and a third polynucleotide (complementary to a second portion of the first polynucleotide). The first, second and third polynucleotides are annealed, ligated and optionally, these steps are repeated. A fourth polynucleotide, which is essentially complementary to at least a portion of the first sequence, coupled to a first indicator is then provided. A fifth and/or sixth polynucleotide is provided. The fifth polynucleotide is essentially identical to at least a portion of the second sequence of the second polynucleotide and/or to at least a portion of the third polynucleotide. The sixth polynucleotide is essentially complementary to a portion of the second sequence of the second polynucleotide. The third or fifth polynucleotides may be coupled to a second indicator.
FILED	Tuesday, September 29, 2009
APPL NO	12/569648
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2537/1373 (20130101) C12Q 2561/125 (20130101) C12Q 2561/125 (20130101) C12Q 2561/125 (20130101) C12Q 2565/501 (20130101) C12Q 2565/519 (20130101) C12Q 2565/519 (20130101)
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09488622 — Enhanced detection sensitivity with piezoelectric microcantilever sensors

US 09488622	Shih et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) U.S. State Government Commonwealth of Pennsylvania
APPLICANT(S)	Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Qing Zhu (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Qing Zhu (Philadelphia, Pennsylvania)
ABSTRACT	A method for enhancing the detection sensitivity of a piezoelectric microcantilever sensor. The method may involve providing a piezoelectric microcantilever and inducing a change in the Young's modulus during detection of a species of interest. The change in the Young's modulus may be induced or enhanced by the application of a DC bias electric field to the piezoelectric layer that enhances non-180° polarization domain switching of the piezoelectric layer. The change in the Young's modulus may also result from binding of the species of interest to the piezoelectric microcantilever sensor or a combination of binding and application of a DC bias electric field. Significantly enhanced detection sensitivity results from the changed Young's modulus of the piezoelectric layer.
FILED	Wednesday, April 23, 2014
APPL NO	14/259439
ART UNIT	1677 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/036 (20130101) G01N 29/2437 (20130101) Original (OR) Class G01N 33/54373 (20130101) G01N 2291/0257 (20130101)
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09488637 — Combination of single-cell electroporation and electrical recording using the same electrode

US 09488637	Gillis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Kevin Gillis (Columbia, Missouri); Jaya Ghosh (Columbia, Missouri)
ASSIGNEE(S)	THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri)
INVENTOR(S)	Kevin Gillis (Columbia, Missouri); Jaya Ghosh (Columbia, Missouri)
ABSTRACT	Methods for stimulating exocytosis from a cell are provided where the same electrochemical microelectrode is used to electroporate an adjacent cell and then measure quantal exocytosis from the adjacent cell. Also provided are methods for stimulating and measuring exocytosis from a select cell population arrayed on a chip comprising addressable electrodes. Calcium independent stimulation of exocytosis with inorganic anions such as chloride ions is also provided. These methods can provide for specific stimulation of a desired subset of cells without exposing other nearby cells to the stimulus.
FILED	Thursday, January 26, 2012
APPL NO	13/359408
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/487 (20130101) G01N 33/4836 (20130101) G01N 33/48707 (20130101) G01N 33/48728 (20130101) Original (OR) Class G01N 33/48735 (20130101)
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09488640 — Methods of identifying insect-TRPA1 modulators

US 09488640	Garrity et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Paul Garrity (Newton, Massachusetts); Kyeongjin Kang (Lexington, Massachusetts)
ASSIGNEE(S)	Brandeis University (Waltham, Massachusetts)
INVENTOR(S)	Paul Garrity (Newton, Massachusetts); Kyeongjin Kang (Lexington, Massachusetts)
ABSTRACT	The invention provides a screening method for identifying an insect-specific TRPA1 modulator by comparing modulation of an insect TRPA1 and a mammalian TRPA1. The invention further provides method of insect control by applying to an insect a insect-specific TRPA1 modulator identified by the screening method.
FILED	Thursday, March 17, 2011
APPL NO	13/635494
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Fodder A23K 50/90 (20160501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) Original (OR) Class G01N 33/6872 (20130101) G01N 2333/705 (20130101) G01N 2333/43552 (20130101) G01N 2500/02 (20130101)
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09488644 — Assays for determining the effect of an immune cell on a cell from an infectious or neoplastic disease

US 09488644	Silverstein et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Samuel C. Silverstein (New York, New York); John D. Loike (Jamaica, New York); Sadna Budhu (Pelham, New York); Peter P. Lee (San Marino, California)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Samuel C. Silverstein (New York, New York); John D. Loike (Jamaica, New York); Sadna Budhu (Pelham, New York); Peter P. Lee (San Marino, California)
ABSTRACT	An in vitro assay is provided for determining the effect of an immune cell on a cell from an infectious or neoplastic disease. Also provided is an in vitro assay for determining the effect of an activated CD8⁺ T-cell on a sensitized melanoma cell. A method for improving the specific cytolytic activity (SCA) of an immune cell comprising contacting an immune cell with an antigen and an antigen-independent pro-inflammatory agent is provided. A method for ex vivo expansion of antigen-specific CD8⁺ T-cells with enhanced specific cytolytic activity (SCA) comprising culturing the antigen-specific CD8⁺ T-cells in a suitable culture media comprising an amino acid. An in vitro assay is provided for determining the effect of an immune cell on a cell from an infectious or neoplastic disease. A method of treating a subject suffering from an infectious or neoplastic disease with immuno therapy is described.
FILED	Thursday, November 11, 2010
APPL NO	13/509405
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/20 (20130101) A61K 38/20 (20130101) A61K 38/208 (20130101) A61K 38/208 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2503/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5017 (20130101) G01N 33/5047 (20130101) Original (OR) Class
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09488710 — MRI pulse sequence based on Q-space trajectory technique

US 09488710	Boada et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Fernando E. Boada (Wexford, Pennsylvania); Stephen Ross Yutzy (Seven Fields, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Fernando E. Boada (Wexford, Pennsylvania); Stephen Ross Yutzy (Seven Fields, Pennsylvania)
ABSTRACT	Systems and methods capable of improving acquisition times associated with obtaining diffusion-weighted magnetic resonance imaging data are discussed. In aspects, multiple points in q-space can be sampled in a single repetition time (TR). Acquisition time can be further increased using other techniques, such as a radial raster or compressed sensing.
FILED	Friday, March 15, 2013
APPL NO	13/832891
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/561 (20130101) Original (OR) Class G01R 33/56341 (20130101)
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09489474 — Model and methods for identifying points of action in electrically active cells

US 09489474	Hickman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	James Hickman (Orlando, Florida); Peter Molnar (Szombathely, Hungary); Frank Sommerhage (Casselberry, Florida); Jonathan Ernest Hood (Charlotte, North Carolina); Jerry Jenkins (Harvest, Alabama)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	James Hickman (Orlando, Florida); Peter Molnar (Szombathely, Hungary); Frank Sommerhage (Casselberry, Florida); Jonathan Ernest Hood (Charlotte, North Carolina); Jerry Jenkins (Harvest, Alabama)
ABSTRACT	The invention provides a model for generating predicted action potentials of an electrically active cell. The disclosed model includes three operatively coupled submodels. A first submodel contains Hodgkin-Huxley elements generating action potentials based on electrical equivalent circuits. A second submodel is based on reaction kinetics of cell metabolism and is operatively coupled with the first submodel. A third submodel is based on Boolean dynamics representing signaling and associated cellular processes and is operatively coupled with the first and second submodels. The invention includes storing a library of calculated action potentials and associated cellular parameters generated by the model, applying a stimulus to the electrically active cell in vitro so that the cell generates an action potential; and comparing the cell-generated action potential with those stored in the library, wherein a match is predictive of the cellular point of action of the applied stimulus according to the parameters stored.
FILED	Monday, February 07, 2011
APPL NO	13/576442
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class G06F 19/12 (20130101)
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09489495 — System and method for detecting, collecting, analyzing, and communicating event-related information

US 09489495	Li et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Library of Medicine (NLM)
APPLICANT(S)	Peter Chao-Yuan Li (Mclean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Arlington, Virginia); Jae in Yoon (Centreville, Virginia)
ASSIGNEE(S)	GEORGETOWN UNIVERSITY (Washington, District of Columbia)
INVENTOR(S)	Peter Chao-Yuan Li (Mclean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Arlington, Virginia); Mark G. Polyak (Arlington, Virginia); James M. Wilson (Alexandria, Virginia); Jae in Yoon (Centreville, Virginia)
ABSTRACT	A system and method involves detecting operational social disruptive events on a global scale, assigning disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease propagation for containment and forecasting purposes.
FILED	Thursday, August 28, 2008
APPL NO	12/230397
ART UNIT	2451 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 19/3493 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/08072 (20130101)
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09489744 — Parameterized model of 2D articulated human shape

US 09489744	Black et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Brown University (Providence, Rhode Island)
ASSIGNEE(S)	Brown University (Providence, Rhode Island)
INVENTOR(S)	Michael J. Black (Tuebingen, Germany); Oren Freifeld (Menlo Park, California); Alexander W. Weiss (Shirley, Massachusetts); Matthew M. Loper (Tuebingen, Germany); Peng Guan (Mountain View, California)
ABSTRACT	A novel “contour person” (CP) model of the human body is proposed that has the expressive power of a detailed 3D model and the computational benefits of a simple 2D part-based model. The CP model is learned from a 3D model of the human body that captures natural shape and pose variations; the projected contours of this model, along with their segmentation into parts forms the training set. The CP model factors deformations of the body into three components: shape variation, viewpoint change and pose variation. The CP model can be “dressed” with a low-dimensional clothing model, referred to as “dressed contour person” (DCP) model. The clothing is represented as a deformation from the underlying CP representation. This deformation is learned from training examples using principal component analysis to produce so-called eigen-clothing. The coefficients of the eigen-clothing can be used to recognize different categories of clothing on dressed people. The parameters of the estimated 2D body can be used to discriminatively predict 3D body shape using a learned mapping approach. The prediction framework can be used to estimate/predict the 3D shape of a person from a cluttered video sequence and/or from several snapshots taken with a digital camera or a cell phone.
FILED	Friday, February 12, 2016
APPL NO	15/042353
ART UNIT	2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/0085 (20130101) G06T 7/0089 (20130101) Original (OR) Class G06T 17/20 (20130101) G06T 2207/30196 (20130101) G06T 2210/16 (20130101)
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09489752 — Ordered subsets with momentum for X-ray CT image reconstruction

US 09489752	Kim et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	General Electric Company (Schenectady, New York); The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	General Electric Company (Niskayuna, New York)
INVENTOR(S)	Donghwan Kim (Ann Arbor, Michigan); Sathish Ramani (Ann Arbor, Michigan); Jeffrey A. Fessler (Ann Arbor, Michigan); Lin Fu (Niskayuna, New York); Bruno Kristiaan Bernard De Man (Clifton Park, New York)
ABSTRACT	Methods, systems, and non-transitory computer readable media for image reconstruction are presented. Measured data corresponding to a subject is received. A preliminary image update in a particular iteration is determined based on one or more image variables computed using at least a subset of the measured data in the particular iteration. Additionally, at least one momentum term is determined based on the one or more image variables computed in the particular iteration and/or one or more further image variables computed in one or more iterations preceding the particular iteration. Further, a subsequent image update is determined using the preliminary image update and the momentum term. The preliminary image update and/or the subsequent image update are iteratively computed for a plurality of iterations until one or more termination criteria are satisfied.
FILED	Friday, October 04, 2013
APPL NO	14/045816
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 11/006 (20130101) Original (OR) Class G06T 2211/424 (20130101)
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09491087 — Devices and methods for forwarding information base aggregation

US 09491087	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (Memphis, Tennessee)
ASSIGNEE(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (Memphis, Tennessee)
INVENTOR(S)	Beichuan Zhang (Tucson, Arizona); Xin Zhao (Castro Valley, California); Lan Wang (Germantown, Tennessee); Yaoqing Liu (Potsdam, New York)
ABSTRACT	Networking devices and methods for forwarding information base (FIB) aggregation are provided. A networking device includes a processor operable to access entries in a FIB, and aggregate the FIB entries to produce an aggregated FIB with strong forward correctness. In aggregating the FIB entries, the processor is operable to: (a) associate the FIB entries with nodes (n) in a patricia trie; (b) traverse the patricia trie depth-first in post-order and determine for each node a next-hop set, without expanding the trie, by merging what would be the next-hop sets of its imaginary children nodes if there is a complete binary tree; and (c) traverse the patricia trie depth-first in pre-order, select for the root node a next-hop from its next-hop set and include the FIB entry associated with the root node in the aggregated FIB, for each node having a selected next-hop that appears in its child's next-hop set, select that next-hop for the child as its next-hop and exclude the FIB entry associated with the child node from the aggregated FIB, and for each child node which does not have in its next-hop set the selected next-hop of its parent, select a next-hop from its next-hop set and include the FIB entry associated with the child node in the aggregated FIB.
FILED	Wednesday, November 27, 2013
APPL NO	14/092717
ART UNIT	2474 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) Original (OR) Class
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Department of Defense (DOD)

09486168 — Implantable electrode system

US 09486168	Bonmassar et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	Giorgio Bonmassar (Lexington, Massachusetts); Alexandra Golby (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Giorgio Bonmassar (Lexington, Massachusetts); Alexandra Golby (Boston, Massachusetts)
ABSTRACT	An electrode array (10) is configured for implantation into a subject. The electrode array (10) includes an organic substrate material (12) configured to be implanted into an in vivo environment and to optionally dissolve after implantation into the in vivo environment and be absorbed by the in vivo environment, and an electrode (14) mounted to the organic substrate material (12) and configured to acquire signals generated by the in vivo environment. The electrode array (10) includes a connection pad (20) mounted to the organic substrate (12), and a conductive trace (16) formed between the electrode (14) and the connection pad (2). The conductive trace (16) includes a conductive ink that is MRI-compatible.
FILED	Friday, April 26, 2013
APPL NO	14/396529
ART UNIT	3739 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0478 (20130101) A61B 5/6846 (20130101) Original (OR) Class A61B 5/6868 (20130101) A61B 2562/046 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/0531 (20130101) A61N 1/0534 (20130101) A61N 2001/086 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49155 (20150115)
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09486332 — Multi-modal neural interfacing for prosthetic devices

US 09486332	Harshbarger et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Sea Systems Command (NAVSEA)
APPLICANT(S)	Stuart D. Harshbarger (Woodbine, Maryland); James D. Beaty (Columbia, Maryland); R. Jacob Vogelstein (Bethesda, Maryland); Nitish V. Thakor (Clarksville, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Stuart D. Harshbarger (Woodbine, Maryland); James D. Beaty (Columbia, Maryland); R. Jacob Vogelstein (Bethesda, Maryland); Nitish V. Thakor (Clarksville, Maryland)
ABSTRACT	Methods and systems to interface between physiological devices and a prosthetic device, including to receive a plurality of types of physiological activity signals from a user, decode a user movement intent from each of the plurality of signals types, and fuse the movement intents into a joint decision to control moveable elements of the prosthetic device.
FILED	Friday, April 15, 2011
APPL NO	14/110508
ART UNIT	3738 — Miscellaneous Articles, Stock Material
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/72 (20130101) Original (OR) Class A61F 2002/5058 (20130101) A61F 2002/5059 (20130101) A61F 2002/5061 (20130101) A61F 2002/5063 (20130101)
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09486533 — Pharmaceutical compositions for high-capacity targeted delivery

US 09486533	Gmeiner
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S)	William H. Gmeiner (Yadkinville, North Carolina)
ABSTRACT	Provided herein are aptamers and pharmaceutical compositions comprising the same. In some embodiments, the aptamer selectively binds a protein of interest such as an extracellular receptor protein of interest (e.g., a cancer cell extracellular receptor protein, which may be differentially expressed in some embodiments). In some embodiments, the aptamer is directly linked by covalent bonding (e.g., via a geminal diamine linkage) to from 2 to 10 toxin compounds. Also provided herein is a method of selecting an aptamer that specifically binds to a protein expressed by a cell of interest, wherein in some embodiments the aptamer comprises at least one binding site for one or more active compounds. In some embodiments, primer regions flanking the variable region of the aptamers in the pool contains from 1 to 10 mismatches with respect to said forward or reverse primer.
FILED	Friday, September 26, 2014
APPL NO	14/498444
ART UNIT	1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/704 (20130101) A61K 47/48092 (20130101) Original (OR) Class
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09486554 — Wound care compositions comprising borate (B₂O₃) glass-based particles

US 09486554	Jung et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S)	The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Steven B. Jung (Rolla, Missouri); Delbert E. Day (Rolla, Missouri)
ABSTRACT	Glass-based angiogenic particles of a biocompatible material which comprises 40 to about 80 wt% borate (B₂O₃) intermixed into a carrier which is an ointment, cream, or surgical glue.
FILED	Monday, September 16, 2013
APPL NO	14/028148
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00008 (20130101) A61F 13/00034 (20130101) A61F 13/069 (20130101) A61F 2013/00157 (20130101) A61F 2013/00221 (20130101) A61F 2013/00519 (20130101) A61F 2013/00829 (20130101) A61F 2013/00936 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 33/16 (20130101) A61K 33/22 (20130101) A61K 33/26 (20130101) A61K 33/30 (20130101) A61K 33/32 (20130101) A61K 33/34 (20130101) A61K 33/38 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) A61L 15/42 (20130101) A61L 15/64 (20130101) A61L 15/425 (20130101) A61L 17/00 (20130101) Original (OR) Class A61L 26/0004 (20130101) A61L 26/0009 (20130101) A61L 26/0085 (20130101) A61L 2400/12 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09486854 — Ceramic and refractory metal core assembly

US 09486854	Propheter-Hinckley
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	Tracy A. Propheter-Hinckley (Manchester, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	Tracy A. Propheter-Hinckley (Manchester, Connecticut)
ABSTRACT	A core assembly for forming a cast component includes a refractory metal core and a ceramic core element. The refractory metal core includes first and second ends and sides extending from the first end to the second end. The ceramic core element includes a slot positioned between first and second lands, each land having an inner surface facing the slot and an adjacent outer surface. The first end of the refractory metal core is secured within the slot with an adhesive, and the refractory metal core extends from the ceramic core element in both a longitudinal and a transverse direction. The slot, lands, and refractory metal core form a core assembly providing access paths to the sides of the refractory metal core. Surplus adhesive is removed from the refractory metal core via the access paths. Investment casting provides the component with an internal passage and an internal cooling circuit.
FILED	Monday, September 10, 2012
APPL NO	13/608210
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Foundry Moulding B22C 9/04 (20130101) B22C 9/103 (20130101) Original (OR) Class Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/00 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/21 (20130101) F05D 2230/211 (20130101) F05D 2300/13 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09486918 — System and method for quick scripting of tasks for autonomous robotic manipulation

US 09486918	Earl et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Darren J. Earl (Los Angeles, California); Derek W. Mitchell (Calabasas, California); Heiko Hoffmann (Simi Valley, California)
ABSTRACT	Described is a system for a system for autonomous robotic manipulation. The system is configured to receiving a selected task from a task file library. The task is associated with causing a robot end effector to perform an action with a particular item, such as picking up an item. The selected task is transformed into a state machine. Thereafter, the system executes the state machine and, in doing so, causes the robot end effector to perform the selected task.
FILED	Wednesday, March 12, 2014
APPL NO	14/207519
ART UNIT	3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/163 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

09486919 — Dual-axis robotic joint

US 09486919	Thorne et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Google Inc. (Mountain View, California)
ASSIGNEE(S)	Google Inc. (Mountain View, California)
INVENTOR(S)	Christopher Everett Thorne (Mountain View, California); Michael Patrick Murphy (Mountain View, California)
ABSTRACT	Example joints for a robotic device are provided. An example robotic joint may include an upper portion, a lower portion, and a connecting link positioned between the upper portion and the lower portion. The upper portion may be coupled to the connecting link via a first revolute joint, and the lower portion may be coupled to the connecting link via a second revolute joint. The robotic joint may also include an actuator having a first end coupled to the upper portion and a second end coupled to the connecting link, where the actuator is configured to apply a torque to the connecting link. The robotic joint may also include a coupling element configured to transfer the torque applied to the connecting link into a rotational motion of the lower portion about the second revolute joint.
FILED	Wednesday, August 13, 2014
APPL NO	14/458365
ART UNIT	3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/1075 (20130101) B25J 9/1633 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

09487479 — Small molecule inhibitors of N-terminus activation of the androgen receptor

US 09487479	Sadar et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Marianne D. Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Jun Wang (New Westminster, Canada); Raymond J. Andersen (Vancouver, Canada); David E. Williams (Vancouver, Canada); Mike Leblanc (Vancouver, Canada); Lu-Ping Yan (Vancouver, Canada)
ASSIGNEE(S)	The University of British Columbia (Vancouver, BC, Canada); British Columbia Cancer Agency Branch (Vancouver, BC, Canada)
INVENTOR(S)	Marianne D. Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Jun Wang (New Westminster, Canada); Raymond J. Andersen (Vancouver, Canada); David E. Williams (Vancouver, Canada); Mike Leblanc (Vancouver, Canada); Lu-Ping Yan (Vancouver, Canada)
ABSTRACT	Compounds having a structure of Formula (A) are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are provided. Uses of compounds having a structure of Formula (F) for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.
FILED	Monday, August 24, 2009
APPL NO	12/999035
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) Heterocyclic Compounds C07D 207/38 (20130101) Original (OR) Class
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09487711 — Process for the conversion of fatty acids and derivatives thereof

US 09487711	Davis et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	David Davis (County Durham, United Kingdom); Cornelis Martinus Lok (The Hague, Netherlands); Michael John Watson (Eaglescliffe, United Kingdom); Aalbert Zwijnenburg (Doetinchem, Netherlands)
ASSIGNEE(S)	Johnson Matthey PLC (London, United Kingdom)
INVENTOR(S)	David Davis (County Durham, United Kingdom); Cornelis Martinus Lok (The Hague, Netherlands); Michael John Watson (Eaglescliffe, United Kingdom); Aalbert Zwijnenburg (Doetinchem, Netherlands)
ABSTRACT	A process for the production of a hydrocarbon product comprises contacting a feedstock with a catalyst composition comprising an active metal selected from platinum, palladium, nickel, cobalt, copper, ruthenium, rhodium and rhenium and an active porous material which is active for the isomerization of unsaturated hydrocarbons, wherein the feedstock comprises a fatty acid a fatty acid ester, a monoglyceride, a diglyceride or a triglyceride.
FILED	Monday, January 26, 2009
APPL NO	12/865797
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/40 (20130101) B01J 23/70 (20130101) B01J 29/22 (20130101) B01J 29/064 (20130101) B01J 29/67 (20130101) B01J 29/68 (20130101) B01J 29/076 (20130101) B01J 29/7415 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/45 (20130101) C10G 3/47 (20130101) Original (OR) Class C10G 3/49 (20130101) C10G 3/50 (20130101) C10G 45/60 (20130101) C10G 2300/1011 (20130101) C10G 2400/30 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101)
VIEW PATENT	@ USPTO: Full Text PDF

09487890 — Valve for controlling fabric permeability, controllable permeability fabric, and articles using same

US 09487890	Farrell et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Wizbe Innovations LLC (Manchester, Maine)
ASSIGNEE(S)
INVENTOR(S)	Stan Edward Farrell (Manchester, Maine); Robert S Farrell (Northport, Maine)
ABSTRACT	Shape memory actuators are utilized to controllably modify the permeability of fabric and fabric based articles. The SMA actuator operates by changing the geometric permeability or by modifying the weave permeability of the fabric based article, or one or more portions thereof. The invention further provides for applications of the controllable permeability fabric, which include by way of example, various parachute, sail, and filter embodiments.
FILED	Thursday, April 18, 2013
APPL NO	13/865992
ART UNIT	1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 39/08 (20130101) B01D 2201/167 (20130101) Marine Propulsion or Steering B63H 9/0657 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 17/18 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 25/00 (20130101) Original (OR) Class Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 31/002 (20130101)
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09488101 — Adaptive fan reverse core geared turbofan engine with separate cold turbine

US 09488101	Kupratis
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Daniel Bernard Kupratis (Wallingford, Connecticut)
ABSTRACT	A turbine engine includes a first fan including a plurality of fan blades rotatable about an axis and a reverse flow core engine section including a core turbine axially forward of a combustor and compressor. The core turbine drives the compressor about the axis and a transmission system. A geared architecture is driven by the transmission system to drive the first fan at a speed less than that of the core turbine. A second fan is disposed axially aft of the first fan and forwarded of the core engine and a second turbine is disposed between the second fan and the core engine for driving the second fan when not coupled to the transmission.
FILED	Wednesday, March 12, 2014
APPL NO	14/205847
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/107 (20130101) Original (OR) Class F02C 3/145 (20130101) F02C 7/36 (20130101) Jet-propulsion Plants F02K 3/077 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09488110 — Device and method for preventing leakage of air between multiple turbine components

US 09488110	Chan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	George Joe-Kueng Chan (Salem, Massachusetts); Victor Hugo Silva Correia (Milton Mills, New Hampshire); David Hannwacker (Boston, Massachusetts); Robert Proctor (West Chester, Ohio)
ABSTRACT	A turbine comprising a first turbine component being of a first material having a first coefficient of thermal expansion. A second turbine component being of a second material having a second coefficient of thermal expansion, said second turbine component adjacent said first turbine component. A space between said first and second turbine components. A seal assembly sealing said space, wherein at least a portion of said seal assembly has a coefficient of thermal expansion substantially similar to at least one of said first or second turbine components to thereby maintain a seal in said space during thermal expansion or contraction of said first and second turbine components.
FILED	Friday, March 08, 2013
APPL NO	13/790965
ART UNIT	3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) F01D 25/145 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/941 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Y02T 50/675 (20130101) Technical Subjects Covered by Former US Classification Y10T 403/217 (20150115)
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09488438 — Small vehicle encapsulation for torpedo tube vehicle launch

US 09488438	Di Biasio et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Angelo Di Biasio (Narragansett, Rhode Island); Christian L Archeval-Rivera (Middletown, Rhode Island); Christopher A. Harding (Swansea, Massachusetts)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Angelo Di Biasio (Narragansett, Rhode Island); Christian L Archeval-Rivera (Middletown, Rhode Island); Christopher A. Harding (Swansea, Massachusetts)
ABSTRACT	A containment canister is provided for loading a vehicle. In the canister, the vehicle is restrained by a nose cap and a ring which conforms to an aft section of the vehicle. Longitudinal leads support the vehicle and provide glide surfaces during a launch. A casing with flow ports is affixed to an aft end of the containment canister with the casing encompassing an actuator with an extendable arm and an attached plug. The plug is sized to move in alignment with each canister toward a sealing ring. When the arm is extended; the plug seats against the ring. To eject the vehicle, a signal is sent an actuator to retract the plug aft of the flow ports. As the canister is flooded by a water impulse thru the flow ports; the impulse contacts the aft end of the vehicle to expel the vehicle.
FILED	Wednesday, September 30, 2015
APPL NO	14/870105
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/32 (20130101) Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 3/10 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

09488492 — Real-time system for multi-modal 3D geospatial mapping, object recognition, scene annotation and analytics

US 09488492	Samarasekera et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI INTERNATIONAL (Menlo Park, California)
INVENTOR(S)	Supun Samarasekera (Princeton, New Jersey); Raia Hadsell (Princeton Junction, New Jersey); Rakesh Kumar (West Windsor, New Jersey); Harpreet S. Sawhney (Princeton Junction, New Jersey); Bogdan C. Matei (Princeton Junction, New Jersey); Ryan Villamil (Plainsboro, New Jersey)
ABSTRACT	A multi-sensor, multi-modal data collection, analysis, recognition, and visualization platform can be embodied in a navigation capable vehicle. The platform provides an automated tool that can integrate multi-modal sensor data including two-dimensional image data, three-dimensional image data, and motion, location, or orientation data, and create a visual representation of the integrated sensor data, in a live operational environment. An illustrative platform architecture incorporates modular domain-specific business analytics “plug ins” to provide real-time annotation of the visual representation with domain-specific markups.
FILED	Thursday, December 18, 2014
APPL NO	14/575472
ART UNIT	3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 11/02 (20130101) G01C 21/32 (20130101) G01C 21/3673 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00637 (20130101) G06K 9/6267 (20130101) G06K 9/6293 (20130101) Image Data Processing or Generation, in General G06T 17/05 (20130101) G06T 2200/04 (20130101) G06T 2207/10012 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09488544 — Load estimation system for aerodynamic structures

US 09488544	Long
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S)	Kim Chenming Long (Bellevue, Washington)
ABSTRACT	A method and apparatus for identifying loads caused by wind. Information for a group of aircraft parameters recorded by an information recorder is received in an aircraft during operation of the aircraft. A number of loads on an aerodynamic structure of the aircraft is estimated using the information for the group of aircraft parameters.
FILED	Thursday, December 05, 2013
APPL NO	14/097365
ART UNIT	3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/00 (20130101) B64D 2045/0085 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0016 (20130101) Original (OR) Class
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09488547 — Modular system for evaluating helmet and suspension materials for protection of neural cells from simulated trauma

US 09488547	O'Shaughnessy et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Thomas O'Shaughnessy (Arlington, Virginia); Ryan McCulloch (Alexandria, Virginia); Amit Bagchi (Rockville, Maryland); Kirth Simmonds (Clinton, Maryland); Clark Mitchell (Woodbridge, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Thomas O'Shaughnessy (Arlington, Virginia); Ryan McCulloch (Alexandria, Virginia); Amit Bagchi (Rockville, Maryland); Kirth Simmonds (Clinton, Maryland); Clark Mitchell (Woodbridge, Virginia)
ABSTRACT	A modular system is designed to interface cell cultures to a shock tube (simulated blast) and/or drop tower (simulated blunt impact) for testing of helmet and helmet pad materials for mitigating cell injury. It includes a set of layers including helmet material, optionally helmet pad, simulated skin, simulated skull, and simulated bulk brain tissue.
FILED	Monday, September 15, 2014
APPL NO	14/486622
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/0052 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/303 (20130101)
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09488572 — Non-contact probe measurement test bed for millimeter wave and terahertz circuits, integrated devices/components, systems for spectroscopy using sub-wavelength-size-samples

US 09488572	Sertel et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Multidisciplinary University Research Initiative (MURI)
APPLICANT(S)	OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
ASSIGNEE(S)	OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
INVENTOR(S)	Kubilay Sertel (Hillard, Ohio); Cosan Caglayan (Columbus, Ohio); Georgios Trichopoulos (Columbus, Ohio)
ABSTRACT	A test fixture for characterizing a device-under-test (DUT) includes first and second planar antennas and a planar waveguide arranged to guide terahertz (THz) and/or millimeter wave (mmW) radiation between the first and second planar antennas. The planar waveguide is further configured to couple THz and/or mmW radiation guided between the first and second planar antennas with the DUT. A beam forming apparatus is arranged to transmit a probe THz and/or mmW radiation beam to the first planar antenna of the test fixture. An electronic analyzer is configured to wirelessly receive a THz and/or mmW signal emitted by the second planar antenna responsive to transmission of the probe THz and/or mmW radiation beam to the first planar antenna. The planar antennas may be asymmetrical beam-tilted slot antennas.
FILED	Thursday, June 19, 2014
APPL NO	14/309432
ART UNIT	2884 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3581 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2822 (20130101)
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09488777 — Back-side etching and cleaving of substrates

US 09488777	Lee et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Oracle International Corporation (Redwood City, California)
ASSIGNEE(S)	ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California)
INVENTOR(S)	Jin-Hyoung Lee (San Diego, California); Ivan Shubin (San Diego, California); Xuezhe Zheng (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT	A fabrication technique for cleaving a substrate in an integrated circuit is described. During this fabrication technique, a trench is defined on a back side of a substrate. For example, the trench may be defined using photoresist and/or a mask pattern on the back side of the substrate. The trench may extend from the back side to a depth less than a thickness of the substrate. Moreover, a buried-oxide layer and a semiconductor layer may be disposed on a front side of the substrate. In particular, the substrate may be included in a silicon-on-insulator technology. By applying a force proximate to the trench, the substrate may be cleaved to define a surface, such as an optical facet. This surface may have high optical quality and may extend across the substrate, the buried-oxide layer and the semiconductor layer.
FILED	Wednesday, September 11, 2013
APPL NO	14/024227
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/13 (20130101) G02B 6/122 (20130101) Original (OR) Class
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09489180 — Methods and apparatus for joint scheduling and layout optimization to enable multi-level vectorization

US 09489180	Baskaran et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Reservoir Labs, Inc. (New York, New York)
ASSIGNEE(S)	Reservoir Labs, Inc. (New York, New York)
INVENTOR(S)	Muthu Baskaran (Jersey City, New Jersey); Richard A. Lethin (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York)
ABSTRACT	Methods, apparatus and computer software product for source code optimization are provided. In an exemplary embodiment, a first custom computing apparatus is used to optimize the execution of source code on a second computing apparatus. In this embodiment, the first custom computing apparatus contains a memory, a storage medium and at least one processor with at least one multi-stage execution unit. The second computing apparatus contains at least one vector execution unit that allow for parallel execution of tasks on constant-strided memory locations. The first custom computing apparatus optimizes the code for parallelism, locality of operations, constant-strided memory accesses and vectorized execution on the second computing apparatus. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.
FILED	Friday, November 16, 2012
APPL NO	13/679861
ART UNIT	2197 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Electric Digital Data Processing G06F 8/443 (20130101) Original (OR) Class
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09489207 — Processor and method for partially flushing a dispatched instruction group including a mispredicted branch

US 09489207	Burky et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	William E. Burky (Austin, Texas); Brian R. Mestan (Austin, Texas); Dung Q. Nguyen (Austin, Texas); Balaram Sinharoy (Poughkeepsie, New York); Benjamin W. Stolt (Austin, Texas)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	William E. Burky (Austin, Texas); Brian R. Mestan (Austin, Texas); Dung Q. Nguyen (Austin, Texas); Balaram Sinharoy (Poughkeepsie, New York); Benjamin W. Stolt (Austin, Texas)
ABSTRACT	Mechanisms are provided for partial flush handling with multiple branches per instruction group. The instruction fetch unit sorts instructions into groups. A group may include a floating branch instruction and a boundary branch instruction. For each group of instructions, the instruction sequencing unit creates an entry in a global completion table (GCT), which may also be referred to herein as a group completion table. The instruction sequencing unit uses the GCT to manage completion of instructions within each outstanding group. Because each group may include up to two branches, the instruction sequencing unit may dispatch instructions beyond the first branch, i.e. the floating branch. Therefore, if the floating branch results in a misprediction, the processor performs a partial flush of that group, as well as a flush of every group younger than that group.
FILED	Tuesday, April 14, 2009
APPL NO	12/423495
ART UNIT	2183 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 9/3842 (20130101) G06F 9/3851 (20130101) G06F 9/3855 (20130101) G06F 9/3857 (20130101) G06F 9/3861 (20130101) Original (OR) Class
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09489495 — System and method for detecting, collecting, analyzing, and communicating event-related information

US 09489495	Li et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Library of Medicine (NLM)
APPLICANT(S)	Peter Chao-Yuan Li (Mclean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Arlington, Virginia); Jae in Yoon (Centreville, Virginia)
ASSIGNEE(S)	GEORGETOWN UNIVERSITY (Washington, District of Columbia)
INVENTOR(S)	Peter Chao-Yuan Li (Mclean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Arlington, Virginia); Mark G. Polyak (Arlington, Virginia); James M. Wilson (Alexandria, Virginia); Jae in Yoon (Centreville, Virginia)
ABSTRACT	A system and method involves detecting operational social disruptive events on a global scale, assigning disease event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling disease propagation for containment and forecasting purposes.
FILED	Thursday, August 28, 2008
APPL NO	12/230397
ART UNIT	2451 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 19/3493 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/08072 (20130101)
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09489596 — Optimal rapid serial visual presentation (RSVP) spacing and fusion for electroencephalography (EEG)-based brain computer interface (BCI)

US 09489596	Khosla et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Deepak Khosla (Camarillo, California); Matthew S. Keegan (Santa Monica, California); Kevin R. Martin (Oak Park, California)
ABSTRACT	Described is system for optimizing rapid serial visual presentation (RSVP) spacing and fusion. The system receives a sequence of a plurality of rapid serial visual presentation (RSVP) image chips. The plurality of RSVP image chips are generated from an image via a pre-processing step and have a high probability of containing a target of interest. The system alters the order of the sequence of the plurality of RSVP image chips to increase the probability of detection of a true target of interest when presented to a human subject.
FILED	Tuesday, December 09, 2014
APPL NO	14/565094
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6263 (20130101) Original (OR) Class
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09489618 — Electronic comparison systems

US 09489618	Roy et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foudation (West Lafayette, Indiana)
INVENTOR(S)	Kaushik Roy (West Lafayette, Indiana); Mrigank Sharad (West Lafayette, Indiana)
ABSTRACT	An electronic comparison system includes input stages that successively provide bits of code words. One-shots connected to respective stages successively provide a first bit value until receiving a bit having a non-preferred value concurrently with an enable signal, and then provide a second, different bit value. An enable circuit provides the enable signal if at least one of the one-shots is providing the first bit value. A neural network system includes a crossbar with row and column electrodes and resistive memory elements at their intersections. A writing circuit stores weights in the elements. A signal source applies signals to the row electrodes. Comparators compare signals on the column electrodes to corresponding references using domain-wall neurons and store bit values in CMOS latches by comparison with a threshold.
FILED	Tuesday, May 27, 2014
APPL NO	14/287701
ART UNIT	2825 — Semiconductors/Memory
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Original (OR) Class Static Stores G11C 11/16 (20130101) G11C 11/54 (20130101) G11C 13/0007 (20130101) G11C 15/02 (20130101) G11C 15/046 (20130101) Coding; Decoding; Code Conversion in General H03M 1/38 (20130101)
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09489622 — Event-driven universal neural network circuit

US 09489622	Modha
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Dharmendra S. Modha (San Jose, California)
ABSTRACT	The present invention provides an event-driven universal neural network circuit. The circuit comprises a plurality of neural modules. Each neural module comprises multiple digital neurons such that each neuron in a neural module has a corresponding neuron in another neural module. An interconnection network comprising a plurality of digital synapses interconnects the neural modules. Each synapse interconnects a first neural module to a second neural module by interconnecting a neuron in the first neural module to a corresponding neuron in the second neural module. Corresponding neurons in the first neural module and the second neural module communicate via the synapses. Each synapse comprises a learning rule associating a neuron in the first neural module with a corresponding neuron in the second neural module. A control module generates signals which define a set of time steps for event-driven operation of the neurons and event communication via the interconnection network.
FILED	Thursday, February 04, 2016
APPL NO	15/015990
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class G06N 3/049 (20130101) G06N 3/063 (20130101)
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09489631 — Cognitive map-based decision simulation for training (CMDST)

US 09489631	Khan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Research, Development and Engineering Command (RDECOM)
APPLICANT(S)	Columbus State University Research Service Foundation, Inc. (Columbus, Georgia)
ASSIGNEE(S)	Columbus State University Research Service Foundation, Inc. (Columbus, Georgia)
INVENTOR(S)	Mohammed Shamimur Rahman Khan (Columbus, Georgia); Osama George Khouri (Columbus, Georgia); Wayne Charles Summers (Midland, Georgia); Rodrigo Obando (Columbus, Georgia); Vladimir Zanev (Columbus, Georgia); Sebastian Wankun Khor (Bonython, Australia); Robert Smith (LaGrange, Georgia)
ABSTRACT	Disclosed is a Cognitive Map-Based Tactical Decision Simulation for Training (CMDST) uses fuzzy cognitive maps (FCM's) to: 1) model high-stress tactical problems or engagements and their causal relationships; 2) simulate situational activities immediately prior to, during, and following the occurrence of a tactical problem or engagement; 3) calculate the relative values of different courses of action; 4) perform individual performance and comparative analysis of selected courses of action; 5) conduct after action reviews to solidify lessons learned from the simulation; and 6) develop individual decision making action plans to outline specific actions to be undertaken to improve future decision making performance.
FILED	Monday, July 01, 2013
APPL NO	13/932422
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 3/011 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 5/048 (20130101) Original (OR) Class Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/00 (20130101)
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09489731 — Directional diffusion fiber tracking

US 09489731	Schneider et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Walter Schneider (Pittsburgh, Pennsylvania); Sudhir Pathak (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Universith of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Walter Schneider (Pittsburgh, Pennsylvania); Sudhir Pathak (Pittsburgh, Pennsylvania)
ABSTRACT	Systems and methods facilitating high definition fiber tracking are disclosed. These systems and methods can utilize a directional Axonal Volume (dAV) value that can quantify the direction and volume of anisotropic water diffusion in axons to assess brain connection integrity. dAV provides a robust and anatomically interpretable measurement of connectivity strength of axon tracts. One method include receiving diffusion magnetic resonance imaging (dMRI) data, quantifying a vector axonal directional diffusion axon volume while removing extracellular isotropic water, segmenting fiber tracks from the data, voxelizing the fiber tracks into voxels, determining voxel dAV values for each voxel and directions, and determining fiber dAV values for each fiber track based on voxel dAV values. This non-invasive method can measure strength and integrity of brain tracts. Such measurements aid in detection of connection disorders like traumatic brain injury and mapping the location of brain tracts and their projection fields to improve neurosurgical outcomes.
FILED	Thursday, March 15, 2012
APPL NO	14/002545
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/1075 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10092 (20130101) G06T 2207/30016 (20130101)
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09489732 — Visual attention distractor insertion for improved EEG RSVP target stimuli detection

US 09489732	Khosla et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Deepak Khosla (Camarillo, California); Kevin R. Martin (Oak Park, California); David J. Huber (Calabasas, California)
ABSTRACT	Described is a system for improved electroencephalograph (EEG) rapid serial visual presentation (RSVP) target stimuli detection through visual attention distractor insertion. A first RSVP sequence is created comprising a set of image chips. The image chips are a combination of target images containing target events and non-target images containing comment events. A number of visual attention distractors to optimize target event detection is determined, and the determined number of visual attention distractors is inserted into the first RSVP sequence to generate a second RSVP sequence. The second RSVP sequence is reordered to generate a third RSVP sequence. The third RSVP sequence is presented to a user, and an EEG signal is received from the user. Finally, the EEG signal is decoded to identify a true target event via a P300 detection in the EEG signal.
FILED	Wednesday, March 12, 2014
APPL NO	14/206421
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00496 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class
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09489851 — Landing signal officer (LSO) information management and trend analysis (IMTA) system

US 09489851	Ross et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Michael Gregory Ross (Pacific Grove, California); Michael E. McCauley (Carmel, California); Neil Charles Rowe (Monterey, California); Mathias Kolsch (Carmel, California); Arijit Das (Monterey, California); Terry D. Norbraten (Salinas, California)
ABSTRACT	Embodiments in accordance with the invention provide a Landing Signal Officer (LSO) Information Management and Trend Analysis (IMTA) system for electronically capturing landing performance data related to aircraft approaches and landings in an IMTA application residing on a portable electronic device (PED) and for automatically generating performance data and trend analysis of the data. In one embodiment, data is input by user, such as an LSO, to one or more context sensitive graphical user interfaces displayed on a touch screen PED. Data entered to and generated by the IMTA application can be further communicated to and updated by external computer systems and appended with additional data and/or video available from external computer systems.
FILED	Friday, March 27, 2015
APPL NO	14/671143
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/36 (20130101) Electric Digital Data Processing G06F 3/0488 (20130101) G06F 3/04847 (20130101) Traffic Control Systems G08G 5/0043 (20130101) Original (OR) Class
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09489965 — Method and apparatus for acoustic signal characterization

US 09489965	Scheffer et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Research, Development and Engineering Command (RDECOM)
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI International (Menlo Park, California)
INVENTOR(S)	Nicolas Scheffer (San Francisco, California); Luciana Ferrer (Buenos Aires, Argentina)
ABSTRACT	Characterizing an acoustic signal includes extracting a vector from the acoustic signal, where the vector contains information about the nuisance characteristics present in the acoustic signal, and computing a set of likelihoods of the vector for a plurality of classes that model a plurality of nuisance characteristics. Training a system to characterize an acoustic signal includes obtaining training data, the training data comprising a plurality of acoustic signals, where each of the plurality of acoustic signals is associated with one of a plurality of classes that indicates a presence of a specific type of nuisance characteristic, transforming each of the plurality of acoustic signals into a vector that summarizes information about the acoustic characteristics of the signal, to produce a plurality of vectors, and labeling each of the plurality of vectors with one of the plurality of classes.
FILED	Friday, March 15, 2013
APPL NO	13/838512
ART UNIT	2658 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 17/20 (20130101) G10L 25/03 (20130101) G10L 25/27 (20130101) Original (OR) Class
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09490045 — Self-healing composites and applications thereof

US 09490045	Tee et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA SLAC National Accelerator Laboratory (SLAC) Federally Funded Research and Development Center (FFRDC) Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Chee Keong Tee (Stanford, California); Chao Wang (Stanford, California); Hui Wu (Mountain View, California); Yi Cui (Stanford, California); Zhenan Bao (Stanford, California)
ABSTRACT	A battery electrode includes an electrochemically active material and a binder covering the electrochemically active material. The binder includes a self-healing polymer and conductive additives dispersed in the self-healing polymer to provide an electrical pathway across at least a portion of the binder.
FILED	Friday, November 08, 2013
APPL NO	14/075841
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/622 (20130101) H01M 4/624 (20130101) H01M 10/0525 (20130101)
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09490169 — Method of forming vias in silicon carbide and resulting devices and circuits

US 09490169	Ring et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Zoltan Ring (Chapel Hill, North Carolina); Scott Thomas Sheppard (Chapel Hill, North Carolina); Helmut Hagleitner (Zebulon, North Carolina)
ASSIGNEE(S)	Cree, Inc. (Durham, North Carolina)
INVENTOR(S)	Zoltan Ring (Chapel Hill, North Carolina); Scott Thomas Sheppard (Chapel Hill, North Carolina); Helmut Hagleitner (Zebulon, North Carolina)
ABSTRACT	A method of fabricating an integrated circuit on a silicon carbide substrate is disclosed that eliminates wire bonding that can otherwise cause undesired inductance. The method includes fabricating a semiconductor device including a Group III-V semiconductor layer on a surface on a silicon carbide substrate, wherein the semiconductor device defines at least one via through the silicon carbide substrate and the epitaxial layer.
FILED	Tuesday, November 02, 2010
APPL NO	12/917828
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/445 (20130101) H01L 21/76898 (20130101) Original (OR) Class H01L 29/452 (20130101) H01L 29/812 (20130101) H01L 29/1608 (20130101) H01L 29/2003 (20130101) H01L 29/4175 (20130101) H01L 29/7787 (20130101)
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09490188 — Compute intensive module packaging

US 09490188	Arvelo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Security Agency (NSA) Maryland Procurement Office (MPO)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Amilcar R. Arvelo (Poughkeepsie, New York); Michael J. Ellsworth (Lagrangeville, New York); Eric J. McKeever (Poughkeepsie, New York); Thong N. Nguyen (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York)
ABSTRACT	A package for a multi-chip module includes a top cold plate and a bottom plate whose perimeters are in thermal communication so the plates together completely encase the module except for a connector passing through the bottom plate. The cold plate has copper tubing pressed into a groove formed in a serpentine pattern. The perimeter of the cold plate has thermal conduction fins which mate with thermal conduction slots in the perimeter of the bottom plate. Thermal interface material is disposed in gaps between the plates and chips on the module, the gaps having dimensions controlled by support ribs of plates which abut the module substrate. The cold plate is used on the hottest side of the module, e.g., the side having computationally-intensive chips such as ASICs. A densely packed array of these packages can be used in a central electronic complex drawer with a shared coolant circulation system.
FILED	Friday, September 12, 2014
APPL NO	14/485225
ART UNIT	2896 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/34 (20130101) H01L 23/42 (20130101) H01L 23/367 (20130101) Original (OR) Class H01L 23/473 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/30 (20130101)
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09490356 — Growth of high-performance III-nitride transistor passivation layer for GaN electronics

US 09490356	Koehler et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S)	Andrew D. Koehler (Alexandria, Virginia); Travis J. Anderson (Alexandria, Virginia); Karl D. Hobart (Alexandria, Virginia); Francis J. Kub (Arnold, Maryland)
ABSTRACT	Methods for forming a high-quality III-nitride passivation layer on an AlGaN/GaN HEMT. A III-nitride passivation layer is formed on the surface of an AlGaN/GaN HEMT by means of atomic layer epitaxy (ALE), either before or after deposition of a gate metal electrode on the AlGaN barrier layer. Depending on the gate metal and/or the passivation material used, the III-nitride passivation layer can be formed by ALE at temperatures between about 300° C. and about 85020 C. In a specific embodiment, the III-nitride passivation layer can be an AlN layer formed by ALE at about 550° C. after deposition of a Schottky metal gate electrode. The III-nitride passivation layer can be grown so as to conformally cover the entire device, providing a hermetic seal that protects the against environmental conditions.
FILED	Friday, March 25, 2016
APPL NO	15/080620
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/02458 (20130101) H01L 21/02661 (20130101) H01L 21/30604 (20130101) H01L 29/2003 (20130101) H01L 29/7787 (20130101) Original (OR) Class H01L 29/66462 (20130101)
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09490454 — Method for producing a high efficiency organic light emitting device having a transparent composite electrode comprising a film of conductive nanowires, carbon nanoparticles, light scattering nanoparticles, and a polymer support

US 09490454	Pei
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Qibing Pei (Calabasas, California)
ABSTRACT	A method for producing high efficiency organic light emitting devices, that have an organic semiconductor active layer sandwiched between electrodes where at least one of the electrodes is a film of conductive nanowires, carbon nanoparticles, light scattering nanoparticles and a polymer support. The light scattering nanoparticles can be incorporated in the conductive nanowires, carbon nanoparticle or polymer support elements of the electrode. The second electrode can be identical to the first to provide a symmetrical device or can be a conductive paste or metal layer. The entire process, including the formation of both of the electrodes, the emissive polymer layer, and the substrate, may be carried out by solution processing.
FILED	Tuesday, January 20, 2015
APPL NO	14/600194
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0037 (20130101) H01L 51/0048 (20130101) H01L 51/56 (20130101) H01L 51/5012 (20130101) H01L 51/5016 (20130101) H01L 51/5032 (20130101) H01L 51/5056 (20130101) H01L 51/5206 (20130101) H01L 51/5215 (20130101) H01L 51/5268 (20130101) Original (OR) Class H01L 2251/5338 (20130101) H01L 2251/5369 (20130101)
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09490517 — High frequency power combiner/divider

US 09490517	Wu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Nuvotronics, LLC (Radford, Virginia)
ASSIGNEE(S)	Nuvotronics, Inc. (Radford, Virginia)
INVENTOR(S)	Donald X. Wu (Diamond Bar, California); David Sherrer (Cary, North Carolina); Jean-Marc Rollin (Chapel Hill, North Carolina)
ABSTRACT	Radio frequency (RF) power amplifiers are provided which may include high power, wideband, microwave or millimeter-wave solid state power amplifiers based on waveguide power combiner/dividers.
FILED	Wednesday, June 17, 2015
APPL NO	14/741775
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/12 (20130101) Original (OR) Class H01P 5/12 (20130101) H01P 5/024 (20130101) H01P 11/002 (20130101) Amplifiers H03F 3/195 (20130101) H03F 3/211 (20130101) H03F 3/602 (20130101)
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09490605 — Parametric comb generation via nonlinear wave mixing in high-Q optical resonator coupled to built-in laser resonator

US 09490605	Gaeta et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	Alexander Gaeta (Ithaca, New York); Michal Lipson (Ithaca, New York); Adrea R. Johnson (Ithaca, New York); Yoshitomo Okawachi (Lansing, New York)
ABSTRACT	The disclosed technology, in one aspect, includes an optical comb generator device which includes a laser cavity that includes an optical gain material to provide an optical gain and an optical path to allow laser light to circulate inside the laser cavity; and a high-Q resonator optically coupled in the optical path inside the laser cavity so that the laser light generated and sustained inside the laser cavity is in optical resonance with the high-Q resonator to cause laser light stored inside the high-Q resonator to have an optical intensity above a four wave mixing threshold of the high-Q resonator to cause parametric four wave mixing so as to produce an optical comb of different optical frequencies.
FILED	Tuesday, April 22, 2014
APPL NO	14/786319
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/395 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/082 (20130101) H01S 3/083 (20130101) H01S 3/0627 (20130101) H01S 3/0637 (20130101) H01S 3/1028 (20130101) H01S 3/1083 (20130101) Original (OR) Class H01S 3/1603 (20130101) H01S 3/06791 (20130101) H01S 3/08086 (20130101) H01S 3/10061 (20130101) H01S 5/5054 (20130101) H01S 5/5063 (20130101)
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09490728 — Magnetoelectric energy harvesting

US 09490728	Finkel et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Peter Finkel (Baltimore, Maryland); Ahmed H Amin (North Attleboro, Massachusetts); Marilyn Wun-Fogle (Potomac, Maryland); James B Restorff (College Park, Maryland); Joseph J Stace (Narragansett, Rhode Island); Colin J Murphy (Newport, Rhode Island)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Peter Finkel (Baltimore, Maryland); Ahmed H Amin (North Attleboro, Massachusetts); Marilyn Wun-Fogle (Potomac, Maryland); James B Restorff (College Park, Maryland); Joseph J Stace (Narragansett, Rhode Island); Colin J Murphy (Newport, Rhode Island)
ABSTRACT	An energy harvesting device for harvesting energy from a moving structure includes a housing allowing transmission of magnetic fields therethrough. A piezoelectric material capable of a phase transition and a magnetostrictive material capable of a structural change when subjected to a magnetic field are mechanically coupled to each other in the housing. An adjustable pre-stress means is positioned between the housing and the combination of the piezoelectric and magnetostrictive materials. Electrical contacts are positioned on the piezoelectric material. A magnet is mounted on the moving structure. The housing is mounted in sufficient proximity to the magnet for the magnetic field of the magnet to induce the structural change in the magnetostrictive material.
FILED	Thursday, November 20, 2014
APPL NO	14/548414
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Electric Machines Not Otherwise Provided for H02N 2/18 (20130101) Original (OR) Class
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09490756 — Phase-stiff RF power amplifier for phased array transmit/receive modules

US 09490756	Babic
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Eridan Communications, Inc. (San Francisco, California)
ASSIGNEE(S)	Eridan Communications, Inc. (San Francisco, California)
INVENTOR(S)	Dubravko Babic (Milpitas, California)
ABSTRACT	A phase-stiff radio frequency power amplifier (RFPA) is disclosed. The high phase-stiffness property of the RFPA obviates the need for a circulator or other isolation device in applications where the RFPA is used to implement the high-power amplifier in a transmit-receive module (TRM) configured for use in a phased array. The phase-stiff RFPA is designed to operate in switch-mode, resulting in high energy efficiency. Together, the high energy efficiency and high phase-stiffness attributes of the RFPA afford the ability to construct a phased array having a SWaP (Size, Weight and Power) performance that far surpasses that which can be possibly achieved in a phased array constructed from conventional TRMs.
FILED	Monday, January 18, 2016
APPL NO	14/997640
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Amplifiers H03F 1/56 (20130101) Original (OR) Class H03F 3/19 (20130101) H03F 3/217 (20130101) H03F 2200/387 (20130101) H03F 2200/451 (20130101)
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09490862 — Reflective-type antenna band and polarization selectable transceiver using a rotatable quarter-wave plate

US 09490862	Brown et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Kenneth W. Brown (Yucaipa, California); Travis B. Feenstra (Calimesa, California); Alan Rattray (Alta Loma, California); Samuel De La Torre (Rancho Cucamonga, California)
ABSTRACT	A low-loss band and polarization-selectable gender-selectable transceiver for use with a reflector-type antenna suitable for the E-band frequency allocation as well as other RF bands in which the upper and lower bands are separated by a stop band. In addition to providing the gender-selectable combination of the upper and lower bands for transmit and receive, this topology allows for the selection of transmit, and receive polarizations. A transceiver may transmit and receive on the same or on orthogonal polarizations. Paired transceivers may transmit on the same or on orthogonal polarizations. This is accomplished by integrating a rotatable polarizer (e.g. a ¼ wave plate) and a polarization duplexer (e.g. an orthomode transducer) in a FDD (Frequency-Domain Duplexed) system. The rotatable polarizer allows for selection of both transmit and receive bands and polarizations.
FILED	Tuesday, February 18, 2014
APPL NO	14/182904
ART UNIT	2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 13/0258 (20130101) H01Q 15/244 (20130101) Transmission H04B 1/401 (20130101) Original (OR) Class
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09490866 — Passive leakage cancellation networks for duplexers and coexisting wireless communication systems

US 09490866	Goel et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Ankush Goel (San Jose, California); Behnam Analui (Irvine, California); Hossein Hashemi (Pacific Palisades, California)
ASSIGNEE(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S)	Ankush Goel (San Jose, California); Behnam Analui (Irvine, California); Hossein Hashemi (Pacific Palisades, California)
ABSTRACT	A passive cancellation network may include a transmit input having a configuration that passively receives a transmit signal from a transmitter that is to be wirelessly transmitted; a transmit output having a configuration that passively delivers the transmit signal after processing by the passive cancellation network; a receive input having a configuration that passively receives a receive signal that includes undesirable leakage from the transmit signal; a receive output having a configuration that passively delivers the receive signal after processing by the passive cancellation network; and a passive feed forward cancellation circuit that passively cancels at least a portion of the undesired leakage from the transmit signal in the receive signal in a feed forward manner.
FILED	Tuesday, December 10, 2013
APPL NO	14/102244
ART UNIT	2464 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 1/525 (20130101) Original (OR) Class
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09491122 — Systems and methods for server and switch failover in a black core network

US 09491122	Morrison et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Dennis A. Morrison (Hampstead, New Hampshire); Nicholas R. Desany (Melrose, Massachusetts); Allan R. Peckham (Exeter, Rhode Island); Donald L. Chaloupka (Wakefield, Rhode Island)
ABSTRACT	A black core network system and method, wherein the system includes a ciphertext network, a server having a bonding module and a plurality of network interfaces, a plurality of encryptor devices and one or more routers, wherein each router is connected through one or more of the server network interfaces to the server and through one or more encryptor devices to the ciphertext network. The server establishes, in the bonding module, a server gateway for each server network interface, selects a first network interface as primary link and a second server network interface as backup link, and sends routing metric information out through the primary link and the backup link, wherein sending includes sending metric information indicating that the cost of routing through the primary link is less than the cost of routing through the backup link. When the server receives, from one of the one or more routers, an indication that there is a link failure on the primary link, the server manipulates the server gateway for the second server network interface to direct traffic for the primary link out the second server network interface, wherein the second link becomes the new primary link and the server sends routing metric information out through the new primary link to the second router.
FILED	Friday, October 17, 2014
APPL NO	14/516762
ART UNIT	2472 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 45/22 (20130101) H04L 45/28 (20130101) H04L 49/557 (20130101) Original (OR) Class
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09491378 — Methods and systems for detection and identification of concealed materials

US 09491378	Kane et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	James A. Kane (Needham Heights, Massachusetts); Ranganathan Shashidhar (Needham Heights, Massachusetts)
ASSIGNEE(S)	Polestar Technologies, Inc. (Needham Heights, Massachusetts)
INVENTOR(S)	James A. Kane (Needham Heights, Massachusetts); Ranganathan Shashidhar (Needham Heights, Massachusetts)
ABSTRACT	Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating, through a patterning component, regions, where an electromagnetic radiation source, from a number of electromagnetic radiation sources, illuminates the patterning component, each repetition performed with a different wavelength. A number of Global pixelated images are obtained. The number of global pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison.
FILED	Monday, April 07, 2014
APPL NO	14/246606
ART UNIT	2485 — Recording and Compression
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/32 (20130101) G01J 3/42 (20130101) G01J 3/0218 (20130101) G01J 3/0272 (20130101) G01J 3/433 (20130101) G01J 3/2803 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/314 (20130101) G01N 21/8422 (20130101) G01N 2201/0221 (20130101) Optical Elements, Systems, or Apparatus G02B 27/1013 (20130101) Pictorial Communication, e.g Television H04N 5/332 (20130101) Original (OR) Class H04N 5/2256 (20130101)
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09491389 — Focal plane array processing method and apparatus

US 09491389	Kelly et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) National Geospatial Intelligence Agency (NGA)
APPLICANT(S)	Michael Kelly (North Reading, Massachusetts); Brian Tyrrell (Brookline, New Hampshire); Curtis Colonero (Shrewsbury, Massachusetts); Robert Berger (Lexinton, Massachusetts); Kenneth Schultz (Lexington, Massachusetts); James Wey (Arlington, Massachusetts); Daniel Mooney (Dracut, Massachusetts); Lawrence Candell (Arlington, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Michael Kelly (North Reading, Massachusetts); Brian Tyrrell (Brookline, New Hampshire); Curtis Colonero (Shrewsbury, Massachusetts); Robert Berger (Lexinton, Massachusetts); Kenneth Schultz (Lexington, Massachusetts); James Wey (Arlington, Massachusetts); Daniel Mooney (Dracut, Massachusetts); Lawrence Candell (Arlington, Massachusetts)
ABSTRACT	A digital focal plane array includes an all-digital readout integrated circuit in combination with a detector array. The readout circuit includes unit cell electronics, orthogonal transfer structures, and data handling structures. The unit cell electronics include an analog to digital converter. Orthogonal transfer structures enable the orthogonal transfer of data among the unit cells. Data handling structures may be configured to operate the digital focal plane array as a data encryptor/decipherer. Data encrypted and deciphered by the digital focal plane array need not be image data.
FILED	Friday, March 21, 2014
APPL NO	14/221429
ART UNIT	2878 — Optics
CURRENT CPC	Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 20/0021 (20130101) G11B 20/00086 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/12 (20130101) H04L 9/0637 (20130101) H04L 2209/12 (20130101) H04L 2209/805 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 5/378 (20130101) Original (OR) Class H04N 5/772 (20130101) H04N 5/913 (20130101) H04N 21/4223 (20130101) H04N 21/4408 (20130101) H04N 2005/91364 (20130101)
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09491854 — Multi-layer microwave corrugated printed circuit board and method

US 09491854	Quan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S)	Clifton Quan (Arcadia, California); Hee Kyung Kim (El Segundo, California); Fangchou Yang (Los Angeles, California); Kevin C. Rolston (Westchester, California); Edward Marsh Jackson (Long Beach, California)
ABSTRACT	A multi-layer microwave corrugated printed circuit board is provided. In one embodiment, an interconnect assembly includes a first flat flexible layer having a signal conductor and a ground conductor forming a first microstripline or microstrip transmission line, a second folded flexible layer having a signal conductor and a ground conductor forming a second microstripline or microstrip transmission line, the bottom surface of the second folded flexible layer having ridge portions, a non-conductive adhesive layer disposed between the top surface of the first flat flexible layer and the ridge portions of the second folded flexible layer, a signal through-hole extending through the non-conductive adhesive layer and the first flat flexible layer, and two ground through-holes extending through the non-conductive adhesive layer and the second folded flexible layer, wherein the two ground through-holes are disposed on opposite sides of the signal through-hole.
FILED	Thursday, April 18, 2013
APPL NO	13/865730
ART UNIT	2848 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/024 (20130101) H05K 1/028 (20130101) Original (OR) Class H05K 1/144 (20130101) H05K 1/147 (20130101) H05K 3/361 (20130101) H05K 3/4069 (20130101) H05K 3/4614 (20130101) H05K 3/4635 (20130101) H05K 2201/055 (20130101) H05K 2201/058 (20130101) H05K 2201/09109 (20130101) H05K 2201/09318 (20130101) H05K 2201/10378 (20130101) H05K 2203/063 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49126 (20150115) Y10T 29/49155 (20150115)
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09491859 — Grid arrays with enhanced fatigue life

US 09491859	Tolpin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambride, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Dmitry Tolpin (Sharon, Massachusetts); James H. Kelly (West Newbury, Massachusetts); Roger M. Maurais (Goffstown, New Hampshire)
ABSTRACT	Reliability is improved for the mechanical electrical connection formed between a grid array device, such as a pin grid array device (PGA) or a column grid array device (CGA), and a substrate such as a printed circuit board (PCB). Between adjacent PCB pads, a spacing pattern increases toward the periphery of the CGA, creating a misalignment between pads and columns. As part of the assembly method, columns align with the pads, resulting in column tilt that increases from the center to the periphery of the CGA. An advantage of this tilt is that it reduces the amount of contractions and expansions of columns during thermal cycling, thereby increasing the projected life of CGA. Another advantage of the method is that it reduces shear stress, further increasing the projected life of the CGA.
FILED	Thursday, May 23, 2013
APPL NO	13/901398
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2224/16225 (20130101) H01L 2924/00 (20130101) H01L 2924/10253 (20130101) H01L 2924/10253 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/18 (20130101) H05K 1/111 (20130101) Original (OR) Class H05K 3/30 (20130101) H05K 3/3436 (20130101) H05K 2201/068 (20130101) H05K 2201/094 (20130101) H05K 2201/09418 (20130101) H05K 2201/09427 (20130101) H05K 2201/10242 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/611 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/4913 (20150115) Y10T 29/49133 (20150115)
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D0770887 — Retention clip

US D770887	Sudol et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	George Sudol (Kenvil, New Jersey); Michael Hollis (Flanders, New Jersey); Peter Strong (Morristown, New Jersey)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	George Sudol (Kenvil, New Jersey); Michael Hollis (Flanders, New Jersey); Peter Strong (Morristown, New Jersey)
ABSTRACT
FILED	Monday, April 28, 2014
APPL NO	29/489176
ART UNIT	2914 — Design
CURRENT CPC	Tools and hardware D8/395
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Department of Energy (DOE)

09486641 — Incorporating an optical waveguide into a neural interface

US 09486641	Tolosa et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Vanessa Tolosa (Oakland, California); Terri L. Delima (Livermore, California); Sarah H. Felix (Oakland, California); Satinderpall S. Pannu (Pleasanton, California); Kedar G. Shah (San Francisco, California); Heeral Sheth (Oakland, California); Angela C. Tooker (Dublin, California)
ABSTRACT	An optical waveguide integrated into a multielectrode array (MEA) neural interface includes a device body, at least one electrode in the device body, at least one electrically conducting lead coupled to the at least one electrode, at least one optical channel in the device body, and waveguide material in the at least one optical channel. The fabrication of a neural interface device includes the steps of providing a device body, providing at least one electrode in the device body, providing at least one electrically conducting lead coupled to the at least one electrode, providing at least one optical channel in the device body, and providing a waveguide material in the at least one optical channel.
FILED	Thursday, March 13, 2014
APPL NO	14/210260
ART UNIT	3769 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 2090/571 (20160201) A61B 2562/12 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/0551 (20130101) A61N 5/0601 (20130101) Original (OR) Class A61N 5/0622 (20130101) A61N 2005/063 (20130101) A61N 2005/0612 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49204 (20150115)
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09486735 — Composite oxygen transport membrane

US 09486735	Lu et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Zigui Lu (East Amherst, New York); Pawel J. Plonczak (Amherst, New York); Jonathan A. Lane (Snyder, New York)
ASSIGNEE(S)	PRAXAIR TECHNOLOGY, INC. (Danbury, Connecticut)
INVENTOR(S)	Zigui Lu (East Amherst, New York); Pawel J. Plonczak (Amherst, New York); Jonathan A. Lane (Snyder, New York)
ABSTRACT	A method is described of producing a composite oxygen ion membrane and a composite oxygen ion membrane in which a porous fuel oxidation layer and a dense separation layer and optionally, a porous surface exchange layer are formed on a porous support from mixtures of (Ln_1-xA_x)_wCr_1-yB_yO_3-δand a doped zirconia. Preferred materials are (La_0.8Sr_0.2)_0.95Cr_0.7Fe_0.3O_3-δfor the porous fuel oxidation layer, (La_0.8Sr_0.2)_0.95Cr_0.5Fe_0.5O_3-δfor the dense separation layer, and (La_0.8Sr_0.2)_0.95Cr_0.3Fe_0.7O_3-δfor the porous surface exchange layer. Firing the said fuel activation and separation layers in nitrogen atmosphere unexpectedly allows the separation layer to sinter into a fully densified mass.
FILED	Wednesday, September 16, 2015
APPL NO	14/856038
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) Original (OR) Class B01D 67/0041 (20130101) B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/024 (20130101) B01D 71/028 (20130101) B01D 2255/40 (20130101) B01D 2255/204 (20130101) B01D 2255/402 (20130101) B01D 2255/407 (20130101) B01D 2255/902 (20130101) B01D 2255/2063 (20130101) B01D 2255/20738 (20130101) B01D 2255/20784 (20130101) B01D 2256/12 (20130101) B01D 2257/104 (20130101) B01D 2258/06 (20130101) B01D 2325/023 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/2475 (20130101) B01J 2219/24 (20130101) Non-metallic Elements; Compounds Thereof; C01B 13/0255 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/01 (20130101) C04B 35/016 (20130101) C04B 35/42 (20130101) C04B 35/44 (20130101) C04B 35/48 (20130101) C04B 35/462 (20130101) C04B 35/488 (20130101) C04B 35/2633 (20130101) C04B 38/02 (20130101) C04B 38/02 (20130101) C04B 38/0074 (20130101) C04B 2111/0081 (20130101) C04B 2111/00612 (20130101) C04B 2111/00801 (20130101) C04B 2235/80 (20130101) C04B 2235/768 (20130101) C04B 2235/3208 (20130101) C04B 2235/3217 (20130101) C04B 2235/3222 (20130101) C04B 2235/3224 (20130101) C04B 2235/3225 (20130101) C04B 2235/3227 (20130101) C04B 2235/3229 (20130101) C04B 2235/3232 (20130101) C04B 2235/3234 (20130101) C04B 2235/3243 (20130101) C04B 2235/3246 (20130101) C04B 2235/3262 (20130101) C04B 2235/3268 (20130101) C04B 2235/3272 (20130101) C04B 2235/3274 (20130101) C04B 2235/3275 (20130101) C04B 2235/5445 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1314 (20150115) Y10T 428/24997 (20150401) Y10T 428/24999 (20150401)
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09486742 — Biomimetic membranes and methods of making biomimetic membranes

US 09486742	Rempe et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Susan Rempe (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico); David Michael Rogers (Albuquerque, New Mexico); Ying-Bing Jiang (Albuquerque, New Mexico); Shaorong Yang (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Susan Rempe (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico); David Michael Rogers (Albuquerque, New Mexico); Ying-Bing Jiang (Albuquerque, New Mexico); Shaorong Yang (Albuquerque, New Mexico)
ABSTRACT	The present disclosure is directed to biomimetic membranes and methods of manufacturing such membranes that include structural features that mimic the structures of cellular membrane channels and produce membrane designs capable of high selectivity and high permeability or adsorptivity. The membrane structure, material and chemistry can be selected to perform liquid separations, gas separation and capture, ion transport and adsorption for a variety of applications.
FILED	Thursday, October 06, 2011
APPL NO	13/253964
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 63/063 (20130101) B01D 63/066 (20130101) Original (OR) Class B01D 69/04 (20130101) B01D 69/105 (20130101) B01D 71/02 (20130101) B01D 2323/283 (20130101) B01D 2325/02 (20130101)
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09486765 — Ceramic oxygen transport membrane array reactor and reforming method

US 09486765	Kelly et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Sean M. Kelly (Pittsford, New York); Gervase Maxwell Christie (Amherst, New York); Charles Robinson (Lawtons, New York); Jamie R. Wilson (Maynard, Massachusetts); Javier E. Gonzalez (East Amherst, New York); Uttam R. Doraswami (Tonawanda, New York)
ASSIGNEE(S)	PRAXAIR TECHNOLOGY, INC. (Danbury, Connecticut)
INVENTOR(S)	Sean M. Kelly (Pittsford, New York); Gervase Maxwell Christie (Amherst, New York); Charles Robinson (Lawtons, New York); Jamie R. Wilson (Maynard, Massachusetts); Javier E. Gonzalez (East Amherst, New York); Uttam R. Doraswami (Tonawanda, New York)
ABSTRACT	The invention relates to a commercially viable modular ceramic oxygen transport membrane reforming reactor configured using repeating assemblies of oxygen transport membrane tubes and catalytic reforming reactors.
FILED	Tuesday, October 07, 2014
APPL NO	14/508344
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/009 (20130101) Original (OR) Class B01J 8/065 (20130101) B01J 8/067 (20130101) B01J 12/007 (20130101) B01J 19/242 (20130101) B01J 19/243 (20130101) B01J 19/2425 (20130101) B01J 19/2475 (20130101) B01J 2208/00309 (20130101) B01J 2208/00938 (20130101) B01J 2219/0004 (20130101) B01J 2219/0006 (20130101) B01J 2219/00117 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/382 (20130101) C01B 3/384 (20130101) C01B 13/0255 (20130101) C01B 2203/127 (20130101) C01B 2203/0233 (20130101) C01B 2203/0244 (20130101) C01B 2203/0894 (20130101) Methods of Steam Generation; Steam Boilers F22B 1/003 (20130101) F22B 1/16 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/129 (20151101)
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09486786 — Highly dispersed metal catalyst

US 09486786	Xiao et al.
FUNDED BY	Department of Energy (DOE) Office of Environmental Management (DOE-EM) Savannah River National Laboratory (SRNL) Federally Funded Research and Development Center (FFRDC) Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S)	Xin Xiao (Augusta, Georgia); William L. West (Aiken, South Carolina); William D. Rhodes (Aiken, South Carolina)
ASSIGNEE(S)	SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South, None)
INVENTOR(S)	Xin Xiao (Augusta, Georgia); William L. West (Aiken, South Carolina); William D. Rhodes (Aiken, South Carolina)
ABSTRACT	A supported catalyst having an atomic level single atom structure is provided such that substantially all the catalyst is available for catalytic function. A process of forming a single atom catalyst unto a porous catalyst support is also provided.
FILED	Friday, July 02, 2010
APPL NO	12/803698
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/42 (20130101) B01J 23/62 (20130101) B01J 23/626 (20130101) B01J 23/8913 (20130101) Original (OR) Class B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 37/0201 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/92 (20130101) H01M 4/921 (20130101) H01M 4/925 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101)
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09487565 — Zein composition and methods of production

US 09487565	Lawton, Jr.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Poet Research, Inc. (Sioux Falls, South Dakota)
ASSIGNEE(S)	Poet Research, Inc. (Sioux Falls, South Dakota)
INVENTOR(S)	John W. Lawton, Jr. (Sioux Falls, South Dakota)
ABSTRACT	A high cysteine content zein composition is provided. A method and system for the manufacture of the bioproduct is likewise disclosed herein.
FILED	Thursday, May 22, 2014
APPL NO	14/285416
ART UNIT	1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Peptides C07K 14/425 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101)
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09487600 — Ordered nanoscale domains by infiltration of block copolymers

US 09487600	Darling et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Seth B. Darling (Chicago, Illinois); Jeffrey Elam (Elmhurst, Illinois); Yu-Chih Tseng (Westmont, Illinois); Qing Peng (Downers Grove, Illinois)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Seth B. Darling (Chicago, Illinois); Jeffrey Elam (Elmhurst, Illinois); Yu-Chih Tseng (Westmont, Illinois); Qing Peng (Downers Grove, Illinois)
ABSTRACT	A method of preparing tunable inorganic patterned nanofeatures by infiltration of a block copolymer scaffold having a plurality of self-assembled periodic polymer microdomains. The method may be used sequential infiltration synthesis (SIS), related to atomic layer deposition (ALD). The method includes selecting a metal precursor that is configured to selectively react with the copolymer unit defining the microdomain but is substantially non-reactive with another polymer unit of the copolymer. A tunable inorganic features is selectively formed on the microdomain to form a hybrid organic/inorganic composite material of the metal precursor and a co-reactant. The organic component may be optionally removed to obtain an inorganic features with patterned nanostructures defined by the configuration of the microdomain.
FILED	Friday, August 12, 2011
APPL NO	13/209190
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/42 (20130101) Original (OR) Class
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09487794 — Feruloyl-CoA:monolignol transferase

US 09487794	Wilkerson et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Curtis Wilkerson (Swartz Creek, Michigan); John Ralph (Madison, Wisconsin); Saunia Withers (Lansing, Michigan); Shawn D. Mansfield (Vancouver, Canada)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan); The University of British Columbia (, Canada); Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Curtis Wilkerson (Swartz Creek, Michigan); John Ralph (Madison, Wisconsin); Saunia Withers (Lansing, Michigan); Shawn D. Mansfield (Vancouver, Canada)
ABSTRACT	The invention relates to nucleic acids encoding a feruloyl-CoA:monolignol transferase and the feruloyl-CoA:monolignol transferase enzyme that enables incorporation of monolignol ferulates, for example, including p-coumaryl ferulate, coniferyl ferulate, and sinapyl ferulate, into the lignin of plants.
FILED	Friday, July 22, 2011
APPL NO	13/811855
ART UNIT	1662 — Plants
CURRENT CPC	Compounds of Unknown Constitution C07G 1/00 (20130101) Derivatives of Natural Macromolecular Compounds C08H 6/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) C12N 15/8255 (20130101) Original (OR) Class
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09488452 — Apparatus for rendering at least a portion of a device inoperable and related methods

US 09488452	Daniels et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	Michael A. Daniels (Idaho Falls, Idaho); Eric D. Steffler (Idaho Falls, Idaho); Steven D. Hartenstein (Idaho Falls, Idaho); Ronald S. Wallace (Ucon, Idaho)
ABSTRACT	Apparatus for rendering at least a portion of a device inoperable may include a containment structure having a first compartment that is configured to receive a device therein and a movable member configured to receive a cartridge having reactant material therein. The movable member is configured to be inserted into the first compartment of the containment structure and to ignite the reactant material within the cartridge. Methods of rendering at least a portion of a device inoperable may include disposing the device into the first compartment of the containment structure, inserting the movable member into the first compartment of the containment structure, igniting the reactant material in the cartridge, and expelling molten metal onto the device.
FILED	Wednesday, April 22, 2015
APPL NO	14/693347
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Cremation Furnaces; Consuming Waste Products by Combustion F23G 5/245 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 5/18 (20130101) Original (OR) Class Electric Digital Data Processing G06F 21/88 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 5/0245 (20130101)
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09488455 — Sabot assembly

US 09488455	Bzorgi
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Security Complex and PANTEX Plant (Y-12) NNSA Critical Mission Site Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S)	Consolidated Nuclear Security, LLC (Reston, Virginia)
ASSIGNEE(S)	Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Fariborz Bzorgi (Knoxville, Tennessee)
ABSTRACT	A sabot assembly includes a projectile and a housing dimensioned and configured for receiving the projectile. An air pressure cavity having a cavity diameter is disposed between a front end and a rear end of the housing. Air intake nozzles are in fluid communication with the air pressure cavity and each has a nozzle diameter less than the cavity diameter. In operation, air flows through the plurality of air intake nozzles and into the air pressure cavity upon firing of the projectile from a gun barrel to pressurize the air pressure cavity for assisting in separation of the housing from the projectile upon the sabot assembly exiting the gun barrel.
FILED	Thursday, January 22, 2015
APPL NO	14/602556
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 14/06 (20130101) F42B 14/062 (20130101) Original (OR) Class
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09488456 — Geologic fracturing method and resulting fractured geologic structure

US 09488456	Mace et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Jonathan L. Mace (Los Alamos, New Mexico); Christopher R. Bradley (Chimayo, New Mexico); Doran R. Greening (West Lebanon, New Hampshire); David W. Steedman (Santa Fe, New Mexico)
ABSTRACT	Detonation control modules and detonation control circuits are provided herein. A trigger input signal can cause a detonation control module to trigger a detonator. A detonation control module can include a timing circuit, a light-producing diode such as a laser diode, an optically triggered diode, and a high-voltage capacitor. The trigger input signal can activate the timing circuit. The timing circuit can control activation of the light-producing diode. Activation of the light-producing diode illuminates and activates the optically triggered diode. The optically triggered diode can be coupled between the high-voltage capacitor and the detonator. Activation of the optically triggered diode causes a power pulse to be released from the high-voltage capacitor that triggers the detonator.
FILED	Monday, January 14, 2013
APPL NO	14/370208
ART UNIT	3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 25/34 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/263 (20130101) E21B 43/1185 (20130101) E21B 47/123 (20130101) Ignition; Extinguishing-devices F23Q 21/00 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/02 (20130101) F42B 3/10 (20130101) F42B 3/113 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/42 (20130101) Blasting F42D 1/02 (20130101) F42D 1/05 (20130101) F42D 1/042 (20130101) Original (OR) Class F42D 1/045 (20130101) F42D 3/00 (20130101) F42D 3/04 (20130101) F42D 3/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115)
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09488470 — Method for non-destructive evaluation of ceramic coatings

US 09488470	Peterson et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Southwest Sciences Incorporated (Santa Fe, New Mexico); University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S)	UNIVERSITY OF CONNETICUT (Farmington, Connecticut); SOUTHWEST SCIENCES INCORPORATED (Sante Fe, New Mexico)
INVENTOR(S)	Kristen A. Peterson (Santa Fe, New Mexico); Elias P. Rosen (Chapel Hill, North Carolina); Eric H. Jordan (Storrs-Mansfield, Connecticut); Sina Shahbazmohamadi (New York, New York); Andrei B. Vakhtin (New Mexico, New Mexico)
ABSTRACT	A method for evaluating the condition of a ceramic coating deposited on a substrate comprising illuminating the ceramic coating with light, measuring the intensity of light returned from the ceramic coating as function of depth in the coating and transverse position on the coating, and analyzing the measured light intensities to obtain one or more of intensity of the light returned from the exposed coating surface relative to the intensity of light returned from the coating/substrate interface, intensity of the light returned from the coating/substrate interface relative to the intensity of light returned from the bulk of the ceramic coating, determination of roughness at the exposed surface of the ceramic coating, and determination of roughness of the interface between the ceramic coating and underlying bond coat or substrate.
FILED	Friday, February 14, 2014
APPL NO	14/180914
ART UNIT	2886 — Optics
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0209 (20130101) G01B 11/24 (20130101) G01B 11/2441 (20130101) Original (OR) Class
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09488621 — Particle analysis in an acoustic cytometer

US 09488621	Kaduchak et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS)
APPLICANT(S)	Gregory Kaduchak (Los Alamos, New Mexico); Michael D Ward (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Gregory Kaduchak (Los Alamos, New Mexico); Michael D Ward (Los Alamos, New Mexico)
ABSTRACT	The present invention is a method and apparatus for acoustically manipulating one or more particles.
FILED	Friday, August 10, 2012
APPL NO	13/571662
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0838 (20130101) B01L 2300/0864 (20130101) B01L 2400/0439 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 29/14 (20130101) Original (OR) Class G01N 33/4833 (20130101) G01N 2001/4094 (20130101) G01N 2015/142 (20130101) G01N 2015/149 (20130101) G01N 2015/1081 (20130101) G01N 2015/1415 (20130101)
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09488628 — Gas sensor protection device and method

US 09488628	Boyd et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Robert Bosch GmbH (Stuttgart, Germany)
ASSIGNEE(S)	Robert Bosch GmbH (Stuttgart, Germany)
INVENTOR(S)	David Boyd (Greenville, South Carolina); Craig Magera (Simpsonville, South Carolina)
ABSTRACT	A gas sensor includes a sensor housing and a sensing element located within the sensor housing. The sensing element has a distal end and defines an axis. The gas sensor also includes a sensor protection device coupled to the sensor housing and at least partially surrounding the distal end of the sensing element. The sensor protection device includes a first member coupled to the housing, the first member having a generally rectangular cross-sectional shape in a plane perpendicular to the axis. The first member includes a gas inlet and a gas outlet. The sensor protection device also includes a second member coupled to the housing.
FILED	Wednesday, January 15, 2014
APPL NO	14/155909
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/104 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4077 (20130101) G01N 33/0036 (20130101) Original (OR) Class
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09488854 — High-speed optical phase-shifting apparatus

US 09488854	Zortman
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	William A. Zortman (Corrales, New Mexico)
ABSTRACT	An optical phase shifter includes an optical waveguide, a plurality of partial phase shifting elements arranged sequentially, and control circuitry electrically coupled to the partial phase shifting elements. The control circuitry is adapted to provide an activating signal to each of the N partial phase shifting elements such that the signal is delayed by a clock cycle between adjacent partial phase shifting elements in the sequence. The transit time for a guided optical pulse train between the input edges of consecutive partial phase shifting elements in the sequence is arranged to be equal to a clock cycle, thereby enabling pipelined processing of the optical pulses.
FILED	Thursday, April 11, 2013
APPL NO	13/861069
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/12 (20130101) G02B 2006/12159 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) Original (OR) Class
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09488908 — Rapid fabrication of hierarchically structured supramolecular nanocomposite thin films in one minute

US 09488908	Xu et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Ting Xu (Berkeley, California); Joseph Kao (Berkeley, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Ting Xu (Berkeley, California); Joseph Kao (Berkeley, California)
ABSTRACT	Functional nanocomposites containing nanoparticles of different chemical compositions may exhibit new properties to meet demands for advanced technology. It is imperative to simultaneously achieve hierarchical structural control and to develop rapid, scalable fabrication to minimize degradation of nanoparticle properties and for compatibility with nanomanufacturing. The assembly kinetics of supramolecular nanocomposite in thin films is governed by the energetic cost arising from defects, the chain mobility, and the activation energy for inter-domain diffusion. By optimizing only one parameter, the solvent fraction in the film, the assembly kinetics can be precisely tailored to produce hierarchically structured thin films of supramolecular nanocomposites in approximately one minute. Moreover, the strong wavelength dependent optical anisotropy in the nanocomposite highlights their potential applications for light manipulation and information transmission. The present invention opens a new avenue in designing manufacture-friendly continuous processing for the fabrication of functional nanocomposite thin films.
FILED	Friday, May 29, 2015
APPL NO	14/725617
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 153/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class
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09490045 — Self-healing composites and applications thereof

US 09490045	Tee et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA SLAC National Accelerator Laboratory (SLAC) Federally Funded Research and Development Center (FFRDC) Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Chee Keong Tee (Stanford, California); Chao Wang (Stanford, California); Hui Wu (Mountain View, California); Yi Cui (Stanford, California); Zhenan Bao (Stanford, California)
ABSTRACT	A battery electrode includes an electrochemically active material and a binder covering the electrochemically active material. The binder includes a self-healing polymer and conductive additives dispersed in the self-healing polymer to provide an electrical pathway across at least a portion of the binder.
FILED	Friday, November 08, 2013
APPL NO	14/075841
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/622 (20130101) H01M 4/624 (20130101) H01M 10/0525 (20130101)
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09490113 — Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry

US 09490113	Vertes et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Akos Vertes (Reston, Virginia); Bennett N. Walker (Washington, District of Columbia); Jessica A. Stolee (Washington, District of Columbia); Scott T. Retterer (Knoxville, Tennessee)
ASSIGNEE(S)	The George Washington University (Washington, District of Columbia)
INVENTOR(S)	Akos Vertes (Reston, Virginia); Bennett N. Walker (Washington, District of Columbia); Jessica A. Stolee (Washington, District of Columbia); Scott T. Retterer (Knoxville, Tennessee)
ABSTRACT	The production and use of semiconducting nanopost arrays made by nanofabrication is described herein. These nanopost arrays (NAPA) provide improved laser ionization yields and controllable fragmentation with switching or modulation capabilities for mass spectrometric detection and identification of samples deposited on them.
FILED	Wednesday, April 07, 2010
APPL NO	12/755769
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 33/6851 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0418 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101)
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09490153 — Mechanical alignment of substrates to a mask

US 09490153	Webb et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Varian Semiconductor Equipment Associates, Inc. (Gloucester, Massachusetts)
ASSIGNEE(S)	Varian Semiconductor Equipment Associates, Inc. (Gloucester, Massachusetts)
INVENTOR(S)	Aaron P. Webb (Austin, Texas); Charles T. Carlson (Cedar Park, Texas); Michael Honan (Peabody, Massachusetts); Luigi G. Amato (Hampton Falls, New Hampshire); Christopher Neil Grant (Dripping Springs, Texas); James D. Strassner (Austin, Texas)
ABSTRACT	A plurality of masks is attached to the underside of a mask frame. This attachment is made such that each mask can independently move relative to the mask frame in three directions. This relative movement allows each mask to adjust its position to align with respective alignment pins disposed on a working surface. In one embodiment, each mask is attached to the mask frame using fasteners, where the fasteners have a shaft with a diameter smaller than the diameter of the mounting hole disposed on the mask. A bias element may be used to allow relative movement between the mask and the mask frame in the vertical direction. Each mask may also have kinematic features to mate with the respective alignment pins on the working surface.
FILED	Thursday, July 03, 2014
APPL NO	14/323088
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/682 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49895 (20150115)
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09490318 — Three dimensional strained semiconductors

US 09490318	Voss et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Lars Voss (Livermore, California); Adam Conway (Livermore, California); Rebecca J. Nikolic (Oakland, California); Cedric Rocha Leao (Oakland, California); Qinghui Shao (Fremont, California)
ABSTRACT	In one embodiment, an apparatus includes a three dimensional structure comprising a semiconductor material, and at least one thin film in contact with at least one exterior surface of the three dimensional structure for inducing a strain in the structure, the thin film being characterized as providing at least one of: an induced strain of at least 0.05%, and an induced strain in at least 5% of a volume of the three dimensional structure. In another embodiment, a method includes forming a three dimensional structure comprising a semiconductor material, and depositing at least one thin film on at least one surface of the three dimensional structure for inducing a strain in the structure, the thin film being characterized as providing at least one of: an induced strain of at least 0.05%, and an induced strain in at least 5% of a volume of the structure.
FILED	Friday, June 07, 2013
APPL NO	13/912885
ART UNIT	2898 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02107 (20130101) H01L 27/1021 (20130101) H01L 29/0657 (20130101) Original (OR) Class H01L 29/861 (20130101)
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09490486 — Method for removing strongly adsorbed surfactants and capping agents from metal to facilitate their catalytic applications

US 09490486	Adzic et al.
FUNDED BY	Department of Energy (DOE) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S)	Brookhaven Science Associates, LLC (Upton, New York); The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S)	Radoslav R. Adzic (East Setauket, New York); Kuanping Gong (Cupertino, California); Yun Cai (Berkeley, California); Stanislaus Wong (Stony Brook, New York); Christopher Koenigsmann (Mahopac, New York)
ABSTRACT	A method of synthesizing activated electrocatalyst, preferably having a morphology of a nanostructure, is disclosed. The method includes safely and efficiently removing surfactants and capping agents from the surface of the metal structures. With regard to metal nanoparticles, the method includes synthesis of nanoparticle(s) in polar or non-polar solution with surfactants or capping agents and subsequent activation by CO-adsorption-induced surfactant/capping agent desorption and electrochemical oxidation. The method produces activated macroparticle or nanoparticle electrocatalysts without damaging the surface of the electrocatalyst that includes breaking, increasing particle thickness or increasing the number of low coordination sites.
FILED	Monday, January 07, 2013
APPL NO	13/735919
ART UNIT	1756 — Semiconductors/Memory
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/92 (20130101) H01M 4/9041 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101)
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09490507 — Li-ion battery thermal runaway suppression system using microchannel coolers and refrigerant injections

US 09490507	Bandhauer et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Todd M. Bandhauer (Livermore, California); Joseph C. Farmer (Tracy, California)
ABSTRACT	A battery management system with thermally integrated fire suppression includes a multiplicity of individual battery cells in a housing; a multiplicity of cooling passages in the housing within or between the multiplicity of individual battery cells; a multiplicity of sensors operably connected to the individual battery cells, the sensors adapted to detect a thermal runaway event related to one or more of the multiplicity of individual battery cells; and a management system adapted to inject coolant into at least one of the multiplicity of cooling passages upon the detection of the thermal runaway event by the any one of the multiplicity of sensors, so that the thermal runaway event is rapidly quenched.
FILED	Wednesday, May 22, 2013
APPL NO	13/900417
ART UNIT	3744 — Semiconductors/Memory
CURRENT CPC	Transmission Systems for Measured Values, Control or Similar Signals G08C 17/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/486 (20130101) H01M 10/502 (20130101) Original (OR) Class H01M 10/613 (20150401) H01M 10/6551 (20150401) H01M 10/6556 (20150401) H01M 10/6568 (20150401) H01M 2200/00 (20130101)
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09490766 — Shielded multi-stage EMI noise filter

US 09490766	Kisner et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Roger Allen Kisner (Knoxville, Tennessee); David Lee Fugate (Lenoir City, Tennessee)
ABSTRACT	Electromagnetic interference (EMI) noise filter embodiments and methods for filtering are provided herein. EMI noise filters include multiple signal exclusion enclosures. The multiple signal exclusion enclosures contain filter circuit stages. The signal exclusion enclosures can attenuate noise generated external to the enclosures and/or isolate noise currents generated by the corresponding filter circuits within the enclosures. In certain embodiments, an output of one filter circuit stage is connected to an input of the next filter circuit stage. The multiple signal exclusion enclosures can be chambers formed using conductive partitions to divide an outer signal exclusion enclosure. EMI noise filters can also include mechanisms to maintain the components of the filter circuit stages at a consistent temperature. For example, a metal base plate can distribute heat among filter components, and an insulating material can be positioned inside signal exclusion enclosures.
FILED	Thursday, February 13, 2014
APPL NO	14/180119
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Impedance Networks, e.g Resonant Circuits; Resonators H03H 1/0007 (20130101) Original (OR) Class H03H 7/0115 (20130101) H03H 2001/0021 (20130101) H03H 2001/0028 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0209 (20130101) H05K 1/0233 (20130101) H05K 3/0061 (20130101) H05K 2201/1006 (20130101) H05K 2201/09972 (20130101) H05K 2201/10219 (20130101)
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09491259 — Collectively loading programs in a multiple program multiple data environment

US 09491259	Aho et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Michael E. Aho (Rochester, Minnesota); John E. Attinella (Rochester, Minnesota); Thomas M. Gooding (Rochester, Minnesota); Samuel J. Miller (Rochester, Minnesota)
ABSTRACT	Techniques are disclosed for loading programs efficiently in a parallel computing system. In one embodiment, nodes of the parallel computing system receive a load description file which indicates, for each program of a multiple program multiple data (MPMD) job, nodes which are to load the program. The nodes determine, using collective operations, a total number of programs to load and a number of programs to load in parallel. The nodes further generate a class route for each program to be loaded in parallel, where the class route generated for a particular program includes only those nodes on which the program needs to be loaded. For each class route, a node is selected using a collective operation to be a load leader which accesses a file system to load the program associated with a class route and broadcasts the program via the class route to other nodes which require the program.
FILED	Wednesday, March 13, 2013
APPL NO	13/800948
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/445 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/34 (20130101) Original (OR) Class
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National Science Foundation (NSF)

09486555 — Polyhedral oligomeric silsesquioxane (poss)-based bioactive hybrid glass as a scaffold for hard tissue engineering

US 09486555	Sahai et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Nita Sahai (Akron, Ohio); Xianfeng Zhou (Akron, Ohio)
ASSIGNEE(S)	The University of Akron (Akron, Ohio)
INVENTOR(S)	Nita Sahai (Akron, Ohio); Xianfeng Zhou (Akron, Ohio)
ABSTRACT	A hybrid bioactive glass comprising a plurality of POSS-cages each having at least one flexible arm radiating from an Si atom of the POSS-cage, each POSS-cage being covalently linked to another POSS-cage through an Si—O—Si linkage between two flexible arms. A method of forming a hybrid bioactive glass comprising the steps of providing a plurality of POSS-cages, each having at least one reactive flexible arm radiating from an Si atom detailed by —X—Si[R₁,R₂,R₃], wherein X is an arm extension located between the Si—O—Si linkage and an Si atom of the POSS-cage, wherein R₁, R₂and R₃are also the same or different, and at least one of the R₁, R₂and R₃is an alkoxide, and reacting the plurality of POSS-cages through a sol-gel method to form a covalently-linked network and incorporating Ca+2 ions therein, the sol-gel process comprising hydrolysis and polycondensation reactions of the plurality of POSS-cages.
FILED	Friday, April 17, 2015
APPL NO	14/689808
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/18 (20130101) A61L 27/54 (20130101) A61L 2300/102 (20130101) A61L 2430/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/045 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101)
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09486626 — Passive electric field focus system for in vivo and in vitro applications

US 09486626	Rey et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Jose I. Rey (Tampa, Florida); Richard Gilbert (Temple Terrace, Florida); Mark J. Jaroszeski (Wesley Chapel, Florida); Richard Heller (Norfolk, Virginia)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Jose I. Rey (Tampa, Florida); Richard Gilbert (Temple Terrace, Florida); Mark J. Jaroszeski (Wesley Chapel, Florida); Richard Heller (Norfolk, Virginia)
ABSTRACT	The present invention provides a system and method of directing, focusing, or concentrating electrical charges within a defined electric field so that these charges can be used to exert forces on cells and tissues in vivo and/or cell cultures in vitro. The present invention reduces and/or eliminates the damage at a target site that would normally be caused by an electrode that acts as a current source or sink to accomplish the same task.
FILED	Tuesday, April 07, 2015
APPL NO	14/680739
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/325 (20130101) A61N 1/327 (20130101) Original (OR) Class Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101)
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09486757 — Scale-up of microfluidic devices

US 09486757	Romanowsky et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Mark Romanowsky (Cambridge, Massachusetts); Adam R. Abate (San Francisco, California); David A. Weitz (Bolton, Massachusetts)
ABSTRACT	Parallel uses of microfluidic methods and devices for focusing and/or forming discontinuous sections of similar or dissimilar size in a fluid are described. In some aspects, the present invention relates generally to flow-focusing-type technology, and also to microfluidics, and more particularly parallel use of microfluidic systems arranged to control a dispersed phase within a dispersant, and the size, and size distribution, of a dispersed phase in a multi-phase fluid system, and systems for delivery of fluid components to multiple such devices.
FILED	Tuesday, May 12, 2015
APPL NO	14/710223
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 3/0811 (20130101) B01F 13/0062 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 2219/00015 (20130101) B01J 2219/0097 (20130101) B01J 2219/00783 (20130101) B01J 2219/00828 (20130101) B01J 2219/00831 (20130101) B01J 2219/00833 (20130101) B01J 2219/00837 (20130101) B01J 2219/00889 (20130101) B01J 2219/00891 (20130101) B01J 2219/00975 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 137/8593 (20150401)
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09486768 — Colloids with valence: fabrication, functionalization and directional bonding

US 09486768	Pine et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE) Division of Materials Research (DMR)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	David J. Pine (New York, New York); Yufeng Wang (New York, New York); Yu Wang (New York, New York); Marcus Weck (New York, New York)
ABSTRACT	A method for creating the colloidal analogs of atoms with valence: colloidal particles with chemically distinct surface patches that imitate hybridized atomic orbitals, including sp, sp2, sp3, sp3 d, sp3 d2 and sp3 d3. Functionalized with DNA with single-stranded sticky ends, patches on different particles can form highly directional bonds through programmable, specific and reversible DNA hybridization. These features allow the particles to self-assemble into ‘colloidal molecules’ with triangular, tetrahedral and other bonding symmetries, and should also give access to a rich variety of new microstructured colloidal materials.
FILED	Monday, October 28, 2013
APPL NO	14/438862
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/00 (20130101) Original (OR) Class B01J 13/14 (20130101) B01J 13/0039 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 112/08 (20130101) C08F 212/08 (20130101)
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09487420 — Vegetable oil-based polymers for nanoparticle surface modification

US 09487420	Chisholm et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Bret Ja Chisholm (West Fargo, North Dakota); Achintya Bezbaruah (West Fargo, North Dakota); Harjyoti Kalita (Turlock, California)
ASSIGNEE(S)	NDSU Research Foundation (Fargo, North Dakota)
INVENTOR(S)	Bret Ja Chisholm (West Fargo, North Dakota); Achintya Bezbaruah (West Fargo, North Dakota); Harjyoti Kalita (Turlock, California)
ABSTRACT	Amphiphilic copolymers formed from plant oil-derived vinyl ether monomers and polyethylene glycol alkyl vinyl ethers are provided. Nanoparticles coated with these amphiphilic polymers are well-suited for water remediation applications.
FILED	Friday, May 17, 2013
APPL NO	13/896874
ART UNIT	1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/70 (20130101) Original (OR) Class C02F 1/705 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 216/1416 (20130101) C08F 2216/1433 (20130101)
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09487451 — Endophytic yeast strains, methods for ethanol and xylitol production, methods for biological nitrogen fixation, and a genetic source for improvement of industrial strains

US 09487451	Doty et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Emerging Frontiers (EF) Division of Molecular and Cellular Biosciences (MCB) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	University of Washington Through Its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S)	University of Washington Through Its Center for Commercialization (Seattle, Washington)
INVENTOR(S)	Sharon L. Doty (Seattle, Washington); James Trotter Staley (Shoreline, Washington); Michael Su (Seattle, Washington); Azra Vajzovic (Kirkland, Washington); Renata Bura (Seattle, Washington); Regina Redman (Seattle, Washington); Zareen Khan (Redmond, Washington)
ABSTRACT	The present invention provides novel endophytic yeast strains capable of metabolizing both pentose and hexose sugars. Methods of producing ethanol and xylitol using the novel endophytic yeast are provided herein. Also provided are methods of fixing nitrogen and fertilizing a crop using the novel endophytic yeast strains provided herein.
FILED	Thursday, March 13, 2014
APPL NO	14/209709
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 15/815 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) C12P 7/10 (20130101) C12P 7/18 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/645 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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09487472 — Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer

US 09487472	Betley et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Theodore Alexander Betley (Cambridge, Massachusetts); Elisabeth Therese Hennessy (Cambridge, Massachusetts)
ABSTRACT	The present invention provides novel synthetic methods for making acyclic secondary amines by reacting an azide with a compound bearing one or more C—H groups, catalyzed by a Fe^II-dipyrromethene complex. The acyclic secondary amines are thought to be formed through an intermolecular nitrene transfer. Also provided herein are methods of synthesizing protected (e.g., Boc- or Fmoc-protected) cyclic secondary amines (e.g., 5-, 6-, and 7-membered cyclic secondary amines) by reacting an azide that bears one or more C—H groups, catalyzed by a Fe^II-dipyrromethene complex. The protected cyclic secondary amines are thought to be formed through an intramolecular nitrene transfer and may be subsequently deprotected to yield cyclic secondary amines.
FILED	Wednesday, February 26, 2014
APPL NO	14/770217
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 209/02 (20130101) Original (OR) Class C07C 209/02 (20130101) C07C 209/02 (20130101) C07C 209/02 (20130101) C07C 211/38 (20130101) C07C 211/40 (20130101) C07C 211/41 (20130101) C07C 2101/10 (20130101) C07C 2101/14 (20130101) C07C 2101/16 (20130101) C07C 2101/18 (20130101) C07C 2103/74 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 207/06 (20130101) C07D 207/16 (20130101) C07D 209/54 (20130101) C07D 211/16 (20130101) C07D 263/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/025 (20130101)
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09487498 — N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors

US 09487498	Toscano et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Cardioxyl Pharmaceuticals, Inc. (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland); Cardioxyl Pharmaceuticals, Inc. (Chapel Hill, North Carolina)
INVENTOR(S)	John P. Toscano (Glen Arm, Maryland); Frederick Arthur Brookfield (Abingdon, United Kingdom); Andrew D. Cohen (Mamaroneck, New York); Stephen Martin Courtney (Abingdon, United Kingdom); Lisa Marie Frost (Abingdon, United Kingdom); Vincent Jacob Kalish (Annapolis, Maryland)
ABSTRACT	The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.
FILED	Thursday, September 17, 2015
APPL NO	14/857308
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 311/48 (20130101) C07C 317/14 (20130101) C07C 323/67 (20130101) Heterocyclic Compounds C07D 213/74 (20130101) C07D 261/10 (20130101) C07D 263/58 (20130101) C07D 285/125 (20130101) C07D 295/096 (20130101) C07D 307/82 (20130101) C07D 309/12 (20130101) Original (OR) Class C07D 317/14 (20130101) C07D 333/62 (20130101)
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09487522 — SSH-2 (slingshot-2) inhibitors and methods for making and using them

US 09487522	Haga et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Science Foundation (NSF) Office of The Director (OD) Office of International Science and Engineering (OISE)
APPLICANT(S)	Jason H. Haga (San Diego, California); Shu Chien (La Jolla, California); Matt Mui (La Jolla, California); Marshall J. Levesque (Philadelphia, Pennsylvania); Phillip D. Pham (San Francisco, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jason H. Haga (San Diego, California); Shu Chien (La Jolla, California); Matt Mui (La Jolla, California); Marshall J. Levesque (Philadelphia, Pennsylvania); Phillip D. Pham (San Francisco, California)
ABSTRACT	In alternative embodiments, the invention provides compositions that inhibit the polypeptide SSH-2, or SlingSHot-2, a phosphatase enzyme that regulates actin filaments, and methods for making and using them, including methods comprising administering compositions of the invention to regulate or modify actin filament polymerization by inhibiting SSH-2, where in one embodiment compositions of the invention slow or inhibit F-actin depolymerization and severing. In alternative embodiments, compositions and methods of the invention are used to slow or inhibit cell motility and/or internal remodeling. In alternative embodiments, compositions and methods of the invention are used to slow or inhibit, or reverse, or ameliorate the progression of a cancer or a metastasis or other uncontrolled or unregulated cell growth, and/or Alzheimer's disease.
FILED	Thursday, March 15, 2012
APPL NO	14/005653
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 31/192 (20130101) A61K 31/365 (20130101) A61K 31/422 (20130101) A61K 31/451 (20130101) A61K 31/497 (20130101) A61K 31/502 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4025 (20130101) Acyclic or Carbocyclic Compounds C07C 311/17 (20130101) Heterocyclic Compounds C07D 211/96 (20130101) C07D 237/32 (20130101) C07D 307/90 (20130101) C07D 417/06 (20130101) C07D 487/04 (20130101) Original (OR) Class
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09487763 — Nonribosomal peptide synthetases

US 09487763	Sherman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) Fogarty International Center (FIC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	David H. Sherman (Ann Arbor, Michigan); Michael Marie Kaufman-Schofield (Ann Arbor, Michigan); Sunit Jain (Ann Arbor, Michigan); Gregory Dick (Ann Arbor, Michigan)
ABSTRACT	The present disclosure is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS)-derived drug and analogs thereof. The invention provides polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS-derived drug, the polypeptides encoded by such polynucleotides, expression vectors comprising the polynucleotides, host cells comprising the polynucleotides or expression vectors, and kits comprising a host cell. Also provided is a method for the production of ET-743, the NRPS-derived drug.
FILED	Friday, May 15, 2015
APPL NO	14/713662
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0051 (20130101) C12N 9/88 (20130101) C12N 9/93 (20130101) C12N 9/0095 (20130101) C12N 9/1007 (20130101) C12N 9/1025 (20130101) C12N 9/1029 (20130101) Original (OR) Class C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/185 (20130101) Enzymes C12Y 108/01007 (20130101) C12Y 118/01002 (20130101) C12Y 201/01 (20130101) C12Y 203/01 (20130101) C12Y 203/0104 (20130101) C12Y 203/01187 (20130101) C12Y 402/01001 (20130101) C12Y 402/01059 (20130101) C12Y 603/04015 (20130101)
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09487804 — Hydroxy- and dicarboxylic-fat synthsis by microbes

US 09487804	San et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	William Marsh Rice University (Houston, Texas)
ASSIGNEE(S)	William Marsh Rice University (Houston, Texas)
INVENTOR(S)	Ka-Yiu San (Houston, Texas); Xixian Xie (Houston, Texas); Leepika Tuli (Houston, Texas); Hui Wu (Houston, Texas)
ABSTRACT	Systems, methods and microbes that allow the biological production of hydroxy fatty acids and dicarboxylic fatty acids are provided. Specifically, hydroxy fatty acids and dicarboxylic fatty acids are produced by microbes that have been engineered to overexpress acyl ACP thioesterase plus an alkane degration pathway, such as AlkBGT or AlkJH These can be in separate microbes or the same microbe, and separate microbes can be co-cultured or sequentially cultured. Continuously fed systems transferring secreted fats from one microbial culture to another can also be used.
FILED	Wednesday, January 28, 2015
APPL NO	14/607624
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) C12P 7/44 (20130101) C12P 7/6409 (20130101) Original (OR) Class Enzymes C12Y 301/02014 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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09487808 — Rapid assembly of multiple arbitrary length DNA fragments

US 09487808	Babb et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Jonathan William Babb (Watertown, Massachusetts); Shuo Cory Li (Cambridge, Massachusetts); Thomas Knight (Cambridge, Massachusetts); Ron Weiss (Newton, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Jonathan William Babb (Watertown, Massachusetts); Shuo Cory Li (Cambridge, Massachusetts); Thomas Knight (Cambridge, Massachusetts); Ron Weiss (Newton, Massachusetts)
ABSTRACT	Aspects herein relate to composition, and related methods, for isolating and assembling DNA molecules without intermediate cloning steps.
FILED	Friday, September 23, 2011
APPL NO	13/825684
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1027 (20130101) C12N 15/1031 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class
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09488582 — Methods for measuring concentrations of chlorinated solvents through raman spectroscopic observation of the vibrational modes of water

US 09488582	Sinfield et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S)	Joseph Victor Sinfield (West Lafayette, Indiana); Chukwukelue Kenneth Monwuba (Baltimore, Maryland)
ABSTRACT	Method for determining concentration of a chlorinated solvent in a non-turbid aqueous solution sample containing the chlorinated solvent is disclosed. The method includes developing a calibration profile relating intensities of Raman returns at a predetermined Raman shift associated with O—H stretching region of water for non-turbid aqueous chlorinated solvent calibration solutions of known concentrations. Intensity of Raman return at the predetermined Raman shift associated with O—H stretching region of the non-turbid aqueous solution sample is measured and compared to the calibration profile to determine the concentration of the chlorinated solvent in the non-turbid aqueous solution sample. For turbid solution samples, a method using turbidity-corrected intensity for the solution sample is disclosed. Alternatively, for turbid solution samples, a method employing a calibration profile utilizing turbid calibration solutions is disclosed.
FILED	Thursday, March 12, 2015
APPL NO	14/656136
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 33/182 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/193333 (20150115)
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09488601 — Material erosion monitoring system and method

US 09488601	Ruege et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	PaneraTech, Inc. (Chantilly, Virginia)
ASSIGNEE(S)	PANERATECH, INC. (Chantilly, Virginia)
INVENTOR(S)	Alexander C. Ruege (Centerville, Virginia); Yakup Bayram (Falls Church, Virginia); Eric K. Walton (Columbus, Ohio)
ABSTRACT	Disclosed is an improved system and method to evaluate the status of a material. The system and method are operative to identify flaws and measure the erosion profile and thickness of different materials, including refractory materials, using electromagnetic waves. The system is designed to reduce a plurality of reflections, associated with the propagation of electromagnetic waves launched into the material under evaluation, by a sufficient extent so as to enable detection of electromagnetic waves of interest reflected from remote discontinuities of the material. Furthermore, the system and method utilize a configuration and signal processing techniques that reduce clutter and enable the isolation of electromagnetic waves of interest. Moreover, the launcher is impedance matched to the material under evaluation, and the feeding mechanism is designed to mitigate multiple reflection effects to further suppress clutter.
FILED	Wednesday, March 26, 2014
APPL NO	14/226102
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 21/0021 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 15/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/02 (20130101) Original (OR) Class
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09488775 — Systems and methods for producing robust chalcogenide optical fibers

US 09488775	Abouraddy et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	Ayman F. Abouraddy (Winter Park, Florida); Guangming Tao (Orlando, Florida); Soroush Shabahang (Orlando, Florida)
ABSTRACT	In one embodiment, a chalcogenide glass optical fiber is produced by forming a billet including a chalcogenide glass mass and a polymer mass in a stacked configuration, heating the billet to a temperature below the melting point of the chalcogenide glass, extruding the billet in the ambient environment to form a preform rod having a chalcogenide glass core and a polymer jacket, and drawing the preform rod.
FILED	Friday, May 03, 2013
APPL NO	14/398548
ART UNIT	2883 — Optics
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 6/0273 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 37/026 (20130101) C03B 37/027 (20130101) C03B 37/01205 (20130101) C03B 37/01274 (20130101) C03B 2201/86 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 13/043 (20130101) C03C 25/18 (20130101) C03C 25/106 (20130101) Optical Elements, Systems, or Apparatus G02B 1/00 (20130101) G02B 1/105 (20130101) G02B 6/036 (20130101) Original (OR) Class G02B 6/02395 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/239 (20150115) Y10T 428/24612 (20150115) Y10T 428/31533 (20150401)
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09489343 — System and method for sparse matrix vector multiplication processing

US 09489343	Bakos
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Jason D. Bakos (Chapin, South Carolina)
ASSIGNEE(S)	University of South Carolina (Columbia, South Carolina)
INVENTOR(S)	Jason D. Bakos (Chapin, South Carolina)
ABSTRACT	Systems and methods for sparse matrix vector multiplication (SpMV) are disclosed. The systems and methods include a novel streaming reduction architecture for floating point accumulation and a novel on-chip cache design optimized for streaming compressed sparse row (CSR) matrices. The present disclosure is also directed to implementation of the reduction circuit and/or processing elements for SpMV processing into a personality for the Convey HC-1 computing device.
FILED	Tuesday, October 07, 2014
APPL NO	14/508198
ART UNIT	2183 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 17/16 (20130101) Original (OR) Class
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09489523 — Systems and methods for file access auditing

US 09489523	Kohno et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Tadayoshi Kohno (Seattle, Washington); Roxana Geambasu (New York, New York); Henry Levy (Seattle, Washington); Steven Gribble (Seattle, Washington)
ASSIGNEE(S)	University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S)	Tadayoshi Kohno (Seattle, Washington); Roxana Geambasu (New York, New York); Henry Levy (Seattle, Washington); Steven Gribble (Seattle, Washington)
ABSTRACT	Systems and methods for providing an auditing file system for theft-prone devices are disclosed. The auditing file system supports fine-grained file auditing: a user may obtain reliable, explicit evidence that no files have been accessed after a device's loss. A user may also disable future file access after a device's loss, even in the absence of device network connectivity. In one embodiment, files are encrypted locally but the encryption keys are stored remotely, so that an audit server is queried for encryption keys to access protected files. By configuring the audit server to refuse to return a particular file's key, the user can prevent new accesses after the device is lost.
FILED	Friday, April 08, 2011
APPL NO	13/640034
ART UNIT	2431 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/62 (20130101) Original (OR) Class G06F 21/88 (20130101) G06F 2221/2101 (20130101)
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09489744 — Parameterized model of 2D articulated human shape

US 09489744	Black et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Brown University (Providence, Rhode Island)
ASSIGNEE(S)	Brown University (Providence, Rhode Island)
INVENTOR(S)	Michael J. Black (Tuebingen, Germany); Oren Freifeld (Menlo Park, California); Alexander W. Weiss (Shirley, Massachusetts); Matthew M. Loper (Tuebingen, Germany); Peng Guan (Mountain View, California)
ABSTRACT	A novel “contour person” (CP) model of the human body is proposed that has the expressive power of a detailed 3D model and the computational benefits of a simple 2D part-based model. The CP model is learned from a 3D model of the human body that captures natural shape and pose variations; the projected contours of this model, along with their segmentation into parts forms the training set. The CP model factors deformations of the body into three components: shape variation, viewpoint change and pose variation. The CP model can be “dressed” with a low-dimensional clothing model, referred to as “dressed contour person” (DCP) model. The clothing is represented as a deformation from the underlying CP representation. This deformation is learned from training examples using principal component analysis to produce so-called eigen-clothing. The coefficients of the eigen-clothing can be used to recognize different categories of clothing on dressed people. The parameters of the estimated 2D body can be used to discriminatively predict 3D body shape using a learned mapping approach. The prediction framework can be used to estimate/predict the 3D shape of a person from a cluttered video sequence and/or from several snapshots taken with a digital camera or a cell phone.
FILED	Friday, February 12, 2016
APPL NO	15/042353
ART UNIT	2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/0085 (20130101) G06T 7/0089 (20130101) Original (OR) Class G06T 17/20 (20130101) G06T 2207/30196 (20130101) G06T 2210/16 (20130101)
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09489973 — Magnetic data storage using induced strain of a magnetostrictive material

US 09489973	Dhagat-Jander et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS) U.S. State Government State of Oregon
APPLICANT(S)	STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (Corvallis, Oregon)
ASSIGNEE(S)	Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Pallavi Dhagat-Jander (Corvallis, Oregon); Albrecht Jander (Corvallis, Oregon)
ABSTRACT	Acoustically assisted magnetic recording can be used in a hard disk drive or a solid state medium. In the described embodiments, otherwise unwriteable high-coercivity media are made amenable to recording by lowering their coercivity via strain induced by acoustic waves. The use of acoustic waves temporarily and locally reduces the magnetic field required to record information on a magnetic recording medium. The process makes use of the magnetostrictive property of a magnetic material by which the magnetic anisotropy of the material is changed by strain. The result of such a change is a reduction in the coercive field, i.e., the magnetic field required to reverse the magnetization direction. Because acoustic waves cause strain, the passage of an acoustic wave through a magnetic material can be used to reduce its coercive field.
FILED	Thursday, February 13, 2014
APPL NO	14/767057
ART UNIT	2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 5/09 (20130101) G11B 5/314 (20130101) G11B 5/825 (20130101) Original (OR) Class G11B 2005/0005 (20130101)
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09490454 — Method for producing a high efficiency organic light emitting device having a transparent composite electrode comprising a film of conductive nanowires, carbon nanoparticles, light scattering nanoparticles, and a polymer support

US 09490454	Pei
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Qibing Pei (Calabasas, California)
ABSTRACT	A method for producing high efficiency organic light emitting devices, that have an organic semiconductor active layer sandwiched between electrodes where at least one of the electrodes is a film of conductive nanowires, carbon nanoparticles, light scattering nanoparticles and a polymer support. The light scattering nanoparticles can be incorporated in the conductive nanowires, carbon nanoparticle or polymer support elements of the electrode. The second electrode can be identical to the first to provide a symmetrical device or can be a conductive paste or metal layer. The entire process, including the formation of both of the electrodes, the emissive polymer layer, and the substrate, may be carried out by solution processing.
FILED	Tuesday, January 20, 2015
APPL NO	14/600194
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0037 (20130101) H01L 51/0048 (20130101) H01L 51/56 (20130101) H01L 51/5012 (20130101) H01L 51/5016 (20130101) H01L 51/5032 (20130101) H01L 51/5056 (20130101) H01L 51/5206 (20130101) H01L 51/5215 (20130101) H01L 51/5268 (20130101) Original (OR) Class H01L 2251/5338 (20130101) H01L 2251/5369 (20130101)
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09490698 — Low input voltage boost converter with peak inductor current control and offset compensated zero detection

US 09490698	Calhoun et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S)	UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S)	Benton Calhoun (Charlottesville, Virginia); Aatmesh Shrivastava (Charlottesville, Virginia)
ABSTRACT	The low input voltage boost converter with peak inductor current control and offset compensated zero detection provide a boost converter scheme to harvest energy from sources with small output voltages. Some embodiments described herein includes a thermoelectric boost converter that combines an I_PEAKcontrol scheme with offset compensation and duty cycled comparators to enable energy harvesting from TEG inputs as low as 5 mV to 10 mV, and the peak inductor current is independent to first order of the input voltage and output voltage. A control circuit can be configured to sample the input voltage (V_IN) and then generate a pulse with a duration inversely proportional to V_INso as to control the boost converter switches such that a substantially constant peak inductor current is generated.
FILED	Wednesday, March 30, 2016
APPL NO	15/085428
ART UNIT	2838 — Electrical Circuits and Systems
CURRENT CPC	Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/156 (20130101) Original (OR) Class
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09490725 — Multi-stage programmable rectifier with efficiency tracking

US 09490725	Xia et al.
FUNDED BY	National Science Foundation (NSF) U.S. State Government State of Oregon
APPLICANT(S)	The State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
ASSIGNEE(S)	Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Lingli Xia (San Diego, California); Patrick Y. Chiang (Corvallis, Oregon); Jiao Cheng (Portland, Oregon)
ABSTRACT	Examples of multi-stage programmable rectifiers are provided herein. Each rectifier stage can include a first transistor and a switch connected to the first transistor. A threshold voltage of the first transistor can be programmed through selection of one of a plurality of voltages available at the switch. Each rectifier stage can also include a second transistor that can be connected in series with the first transistor. An output capacitor can be connected to the second transistor at an output of the rectifier stage. The plurality of voltages provided at the switch allows the threshold voltage of the first transistor to be adjusted in either a positive or negative position to increase efficiency of the rectifier. A calibration process can be used to identify the position of each switch in the rectifier stages that results in the highest efficiency or rectifier output voltage.
FILED	Friday, March 14, 2014
APPL NO	14/212478
ART UNIT	2838 — Electrical Circuits and Systems
CURRENT CPC	Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/25 (20130101) Original (OR) Class H02M 2003/078 (20130101)
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09490815 — Robust, low power, reconfigurable threshold logic array

US 09490815	Vrudhula et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Sarma Vrudhula (Chandler, Arizona); Niranjan Kulkarni (Tempe, Arizona)
ABSTRACT	A field programmable threshold-logic array (FPTLA) includes a number of threshold logic gates and a number of programmable interconnect elements. Each one of the programmable interconnect elements are connected between two or more of the threshold logic gates, such that the programmable interconnect elements route signals between the threshold logic gates. By using threshold logic gates for the FPTLA, the size of the FPTLA may be significantly smaller than conventional solutions. Further, using threshold logic gates results in significant improvements in the computation speed of the FPTLA when compared to conventional solutions.
FILED	Tuesday, July 08, 2014
APPL NO	14/903428
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 19/0013 (20130101) H03K 19/23 (20130101) H03K 19/1778 (20130101) Original (OR) Class H03K 19/17736 (20130101) H03K 19/17768 (20130101)
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09491087 — Devices and methods for forwarding information base aggregation

US 09491087	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (Memphis, Tennessee)
ASSIGNEE(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (Memphis, Tennessee)
INVENTOR(S)	Beichuan Zhang (Tucson, Arizona); Xin Zhao (Castro Valley, California); Lan Wang (Germantown, Tennessee); Yaoqing Liu (Potsdam, New York)
ABSTRACT	Networking devices and methods for forwarding information base (FIB) aggregation are provided. A networking device includes a processor operable to access entries in a FIB, and aggregate the FIB entries to produce an aggregated FIB with strong forward correctness. In aggregating the FIB entries, the processor is operable to: (a) associate the FIB entries with nodes (n) in a patricia trie; (b) traverse the patricia trie depth-first in post-order and determine for each node a next-hop set, without expanding the trie, by merging what would be the next-hop sets of its imaginary children nodes if there is a complete binary tree; and (c) traverse the patricia trie depth-first in pre-order, select for the root node a next-hop from its next-hop set and include the FIB entry associated with the root node in the aggregated FIB, for each node having a selected next-hop that appears in its child's next-hop set, select that next-hop for the child as its next-hop and exclude the FIB entry associated with the child node from the aggregated FIB, and for each child node which does not have in its next-hop set the selected next-hop of its parent, select a next-hop from its next-hop set and include the FIB entry associated with the child node in the aggregated FIB.
FILED	Wednesday, November 27, 2013
APPL NO	14/092717
ART UNIT	2474 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) Original (OR) Class
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National Aeronautics and Space Administration (NASA)

09486772 — Methods of functionalization of carbon nanotubes by photooxidation

US 09486772	Lebron-Colon et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Marisabel Lebron-Colon (N. Ridgeville, Ohio); Michael A. Meador (Strongsville, Ohio)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Marisabel Lebron-Colon (N. Ridgeville, Ohio); Michael A. Meador (Strongsville, Ohio)
ABSTRACT	A method of photooxidizing carbon nanotubes, such as single-walled and multi-walled carbon nanotubes. The nanotubes are purified and dispersed in a solvent, such as n-methyl pyrrolidinone or dimethylformamide. A singlet oxygen sensitizer like Rose Bengal is added to the solution. Oxygen gas is continuously supplied while irradiating the solution while irradiating the solution with ultraviolet light to produce singlet oxygen to oxidize the single-walled carbon nanotubes. Advantageously, the method significantly increases the level of oxidation compared with prior art methods.
FILED	Friday, August 27, 2010
APPL NO	12/870475
ART UNIT	1756 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/123 (20130101) Original (OR) Class B01J 19/127 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0273 (20130101)
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09487450 — Electrokinetic strength enhancement of concrete

US 09487450	Cardenas
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Louisiana Tech University Research Foundation, A Division of Louisiana Tech University Foundation, Inc. (Ruston, Louisiana)
ASSIGNEE(S)	LOUISIANA TECH RESEARCH CORPORATION (Ruston, Louisiana)
INVENTOR(S)	Henry E. Cardenas (Ruston, Louisiana)
ABSTRACT	A method and apparatus for strengthening cementitious concrete by placing a nanoparticle carrier liquid in contact with a first surface of a concrete section and inducing a current across the concrete section at sufficient magnitude and for sufficient time that nanoparticles in the nanoparticle carrier liquid migrate through a significant depth of the concrete section.
FILED	Wednesday, January 23, 2013
APPL NO	13/747904
ART UNIT	1759 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 41/4564 (20130101) Original (OR) Class
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09488103 — Variable cycle intake for reverse core engine

US 09488103	Suciu et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
INVENTOR(S)	Gabriel L Suciu (Glastonbury, Connecticut); Jesse M Chandler (South Windsor, Connecticut); Joseph B Staubach (Colchester, Connecticut)
ABSTRACT	A gas generator for a reverse core engine propulsion system has a variable cycle intake for the gas generator, which variable cycle intake includes a duct system. The duct system is configured for being selectively disposed in a first position and a second position, wherein free stream air is fed to the gas generator when in the first position, and fan stream air is fed to the gas generator when in the second position.
FILED	Monday, December 30, 2013
APPL NO	14/142966
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/20 (20130101) B64D 33/02 (20130101) B64D 2033/0286 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/10 (20130101) F02C 7/042 (20130101) F02C 7/052 (20130101) F02C 7/055 (20130101) F02C 7/057 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/077 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/314 (20130101)
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09488312 — Pulsed plasma lubrication device and method

US 09488312	Hofer et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Richard R. Hofer (Monrovia, California); Donald B. Bickler (Temple City, California); Saverio A. D'Agostino (Santa Rosa Valley, California)
ABSTRACT	Disclosed herein is a lubrication device comprising a solid lubricant disposed between and in contact with a first electrode and a second electrode dimensioned and arranged such that application of an electric potential between the first electrode and the second electrode sufficient to produce an electric arc between the first electrode and the second electrode to produce a plasma in an ambient atmosphere at an ambient pressure which vaporizes at least a portion of the solid lubricant to produce a vapor stream comprising the solid lubricant. Methods to lubricate a surface utilizing the lubrication device in-situ are also disclosed.
FILED	Thursday, January 09, 2014
APPL NO	14/151684
ART UNIT	3654 — Material and Article Handling
CURRENT CPC	Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 103/02 (20130101) C10M 103/04 (20130101) C10M 103/06 (20130101) C10M 107/10 (20130101) C10M 107/32 (20130101) C10M 107/38 (20130101) C10M 107/44 (20130101) C10M 171/00 (20130101) C10M 2201/053 (20130101) C10M 2201/081 (20130101) C10M 2201/082 (20130101) C10M 2201/0413 (20130101) C10M 2201/0613 (20130101) C10M 2201/0653 (20130101) C10M 2201/0663 (20130101) C10M 2201/0803 (20130101) C10M 2201/1023 (20130101) C10M 2201/1033 (20130101) C10M 2205/0285 (20130101) C10M 2209/1023 (20130101) C10M 2209/1033 (20130101) C10M 2213/003 (20130101) C10M 2213/043 (20130101) C10M 2217/0443 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2210/01 (20130101) C10N 2210/02 (20130101) C10N 2210/04 (20130101) C10N 2210/06 (20130101) C10N 2210/07 (20130101) C10N 2210/08 (20130101) C10N 2250/08 (20130101) Lubricating F16N 15/00 (20130101) F16N 39/005 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/48 (20130101) H05H 2240/10 (20130101)
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09488607 — Insulation test cryostat with lift mechanism

US 09488607	Fesmire et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	James E. Fesmire (Titusville, Florida); Adam G. Dokos (Titusville, Florida)
ABSTRACT	A multi-purpose, cylindrical thermal insulation test apparatus is used for testing insulation materials and systems of materials using a liquid boil-off calorimeter system for absolute measurement of the effective thermal conductivity (k-value) and heat flux of a specimen material at a fixed environmental condition (cold-side temperature, warm-side temperature, vacuum pressure level, and residual gas composition). An inner vessel receives liquid with a normal boiling point below ambient temperature, such as liquid nitrogen, enclosed within a vacuum chamber. A cold mass assembly, including upper and lower guard chambers and middle test vessel, is suspended from a lid of the vacuum canister. Each of the three chambers is filled and vented through a single feedthrough. All fluid and instrumentation feedthroughs are mounted and suspended from a top domed lid allowing easy removal of the cold mass. A lift mechanism allows manipulation of the cold mass assembly and insulation test article.
FILED	Tuesday, November 26, 2013
APPL NO	14/090193
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/18 (20130101) Original (OR) Class
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09490899 — Optical tunable-based transmitter for multiple radio frequency bands

US 09490899	Nguyen et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Hung Nguyen (Cleveland, Ohio); Rainee N. Simons (North Olmsted, Ohio); Edwin G. Wintucky (Willoughby, Ohio); Jon C. Freeman (Beachwood, Ohio)
ABSTRACT	An optical tunable transmitter is used to transmit multiple radio frequency bands on a single beam. More specifically, a tunable laser is configured to generate a plurality of optical wavelengths, and an optical tunable transmitter is configured to modulate each of the plurality of optical wavelengths with a corresponding radio frequency band. The optical tunable transmitter is also configured to encode each of the plurality of modulated optical wavelengths onto a single laser beam for transmission of a plurality of radio frequency bands using the single laser beam.
FILED	Friday, May 02, 2014
APPL NO	14/268334
ART UNIT	2637 — Optical Communications
CURRENT CPC	Transmission H04B 10/503 (20130101) Original (OR) Class H04B 10/572 (20130101) Multiplex Communication H04J 14/02 (20130101)
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09491118 — Wireless nanoionic-based radio frequency switch

US 09491118	Nessel et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	James A. Nessel (Cleveland, Ohio); Felix A Miranda (Olmsted Falls, Ohio)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	James A. Nessel (Cleveland, Ohio); Felix A Miranda (Olmsted Falls, Ohio)
ABSTRACT	A nanoionic switch connected to one or more rectenna modules is disclosed. The rectenna module is configured to receive a wireless signal and apply a first bias to change a state of the nanoionic switch from a first state to a second state. The rectenna module can receive a second wireless signal and apply a second bias to change the nanoionic switch from the second state back to the first state. The first bias is generally opposite of the first bias. The rectenna module accordingly permits operation of the nanoionic switch without onboard power.
FILED	Friday, October 05, 2012
APPL NO	13/645799
ART UNIT	2466 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 49/00 (20130101) Original (OR) Class
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U.S. State Government

09486716 — Essential oil extraction apparatus

US 09486716	Hackleman et al.
FUNDED BY	U.S. State Government State of Oregon
APPLICANT(S)	State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
ASSIGNEE(S)	State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S)	David Hackleman (Corvallis, Oregon); Bill Dean (Corvallis, Oregon); Carlos Antar Gutierrez Arriaga (Corvallis, Oregon); Frederick Atadana (Corvallis, Oregon); Tanawat Atichat (Corvallis, Oregon)
ABSTRACT	Disclosed herein are embodiments of an essential oil extraction apparatus. In some embodiments, the apparatus comprises a container configured to hold an essential oil-containing material, an essential oil extract receiver contained in the container, a condenser having an outlet fluidly coupled to the receiver and located relative to the container so as to receive essential oil-containing vapor emitted by the essential oil-containing material; and at least one microwave reflection structure associated with at least one of the container, the receiver or the condenser. The apparatus can have an overall dimension that is sufficiently small so that the apparatus fits inside a standard-sized kitchen microwave oven.
FILED	Friday, November 30, 2012
APPL NO	13/691243
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 3/02 (20130101) B01D 3/40 (20130101) B01D 5/006 (20130101) B01D 8/00 (20130101) Original (OR) Class B01D 11/0211 (20130101) B01D 11/0219 (20130101) B01D 11/0296 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/126 (20130101) B01J 2208/00442 (20130101)
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09488622 — Enhanced detection sensitivity with piezoelectric microcantilever sensors

US 09488622	Shih et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) U.S. State Government Commonwealth of Pennsylvania
APPLICANT(S)	Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Qing Zhu (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Qing Zhu (Philadelphia, Pennsylvania)
ABSTRACT	A method for enhancing the detection sensitivity of a piezoelectric microcantilever sensor. The method may involve providing a piezoelectric microcantilever and inducing a change in the Young's modulus during detection of a species of interest. The change in the Young's modulus may be induced or enhanced by the application of a DC bias electric field to the piezoelectric layer that enhances non-180° polarization domain switching of the piezoelectric layer. The change in the Young's modulus may also result from binding of the species of interest to the piezoelectric microcantilever sensor or a combination of binding and application of a DC bias electric field. Significantly enhanced detection sensitivity results from the changed Young's modulus of the piezoelectric layer.
FILED	Wednesday, April 23, 2014
APPL NO	14/259439
ART UNIT	1677 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/036 (20130101) G01N 29/2437 (20130101) Original (OR) Class G01N 33/54373 (20130101) G01N 2291/0257 (20130101)
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09489973 — Magnetic data storage using induced strain of a magnetostrictive material

US 09489973	Dhagat-Jander et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS) U.S. State Government State of Oregon
APPLICANT(S)	STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (Corvallis, Oregon)
ASSIGNEE(S)	Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Pallavi Dhagat-Jander (Corvallis, Oregon); Albrecht Jander (Corvallis, Oregon)
ABSTRACT	Acoustically assisted magnetic recording can be used in a hard disk drive or a solid state medium. In the described embodiments, otherwise unwriteable high-coercivity media are made amenable to recording by lowering their coercivity via strain induced by acoustic waves. The use of acoustic waves temporarily and locally reduces the magnetic field required to record information on a magnetic recording medium. The process makes use of the magnetostrictive property of a magnetic material by which the magnetic anisotropy of the material is changed by strain. The result of such a change is a reduction in the coercive field, i.e., the magnetic field required to reverse the magnetization direction. Because acoustic waves cause strain, the passage of an acoustic wave through a magnetic material can be used to reduce its coercive field.
FILED	Thursday, February 13, 2014
APPL NO	14/767057
ART UNIT	2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 5/09 (20130101) G11B 5/314 (20130101) G11B 5/825 (20130101) Original (OR) Class G11B 2005/0005 (20130101)
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09490725 — Multi-stage programmable rectifier with efficiency tracking

US 09490725	Xia et al.
FUNDED BY	National Science Foundation (NSF) U.S. State Government State of Oregon
APPLICANT(S)	The State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
ASSIGNEE(S)	Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Lingli Xia (San Diego, California); Patrick Y. Chiang (Corvallis, Oregon); Jiao Cheng (Portland, Oregon)
ABSTRACT	Examples of multi-stage programmable rectifiers are provided herein. Each rectifier stage can include a first transistor and a switch connected to the first transistor. A threshold voltage of the first transistor can be programmed through selection of one of a plurality of voltages available at the switch. Each rectifier stage can also include a second transistor that can be connected in series with the first transistor. An output capacitor can be connected to the second transistor at an output of the rectifier stage. The plurality of voltages provided at the switch allows the threshold voltage of the first transistor to be adjusted in either a positive or negative position to increase efficiency of the rectifier. A calibration process can be used to identify the position of each switch in the rectifier stages that results in the highest efficiency or rectifier output voltage.
FILED	Friday, March 14, 2014
APPL NO	14/212478
ART UNIT	2838 — Electrical Circuits and Systems
CURRENT CPC	Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/25 (20130101) Original (OR) Class H02M 2003/078 (20130101)
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Department of Agriculture (USDA)

09486514 — Bordetella outer-membrane protein antigens and methods of making and using the same

US 09486514	Deora et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S)	Rajendar K. Deora (Winston-Salem, North Carolina); Meenu Mishra (Winston-Salem, North Carolina); Neelima Sukumar (Winston-Salem, North Carolina)
ABSTRACT	An isolated protein or peptide selected from the group consisting of Bordetella colonization factor A (BcfA) protein and antigenic fragments thereof is described, along with an isolated nucleic acid encoding the same, antibodies that bind to the same, methods of producing an immune response in a mammalian subject in need thereof by administering the proteins, peptides or antibodies, and pharmaceutical compositions comprising the same.
FILED	Wednesday, February 03, 2016
APPL NO	15/014665
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/099 (20130101) Original (OR) Class A61K 2039/505 (20130101) A61K 2039/575 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/235 (20130101) C07K 16/1225 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/235 (20130101)
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09486747 — Nanocomposite membranes with advanced antifouling properties under visible light irradiation

US 09486747	Deng et al.
FUNDED BY	Department of the Interior (DOI) U.S. Geological Survey (USGS) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Baolin Deng (Columbia, Missouri); Jun Yin (Columbia, Missouri)
ASSIGNEE(S)	The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Baolin Deng (Columbia, Missouri); Jun Yin (Columbia, Missouri)
ABSTRACT	Nitrogen doped TiO2 (N—TiO2) is used to fabricate Poly(vinyledene fluoride) (PVDF)/N—TiO2 mixed matrix hollow fiber membranes (HFMs) through a phase inversion method to improve filtration efficiencies and antifouling properties. The membranes performances were evaluated based on the water permeability, humic acid (HA) rejection and antifouling properties. Resulting membranes showed brown color and improved hydrophilicity, especially under light irradiation. When compared to original PVDF and PVDF/P25 membrane, mixed matrix membranes containing N—TiO2 nanoparticles (NPs) showed clear photocatalytic activities under visible light irradiation. Also, membrane performance assessments indicated that PVDF/N—TiO2 membranes possessed enhanced water flux, similar HA rejection (e.g., above 96%) and improved fouling resistance with PVDF membranes as a control. The results demonstrate the potential of the suggested methodology for development of membranes with improved water permeability and superior antifouling properties based on photo-degradation processes and photo-induced hydrophilicity enhancement driven by solar light as a renewable energy source.
FILED	Friday, August 07, 2015
APPL NO	14/821390
ART UNIT	1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 65/08 (20130101) B01D 69/02 (20130101) B01D 69/08 (20130101) Original (OR) Class B01D 69/148 (20130101) B01D 71/34 (20130101) B01D 2321/343 (20130101)
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09487712 — Method for producing liquid hydrocarbon fuels directly from lignocellulosic biomass

US 09487712	Shuai et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Li Shuai (Madison, Wisconsin); Xuejun Pan (Fitchburg, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Li Shuai (Madison, Wisconsin); Xuejun Pan (Fitchburg, Wisconsin)
ABSTRACT	A process that directly converts carbohydrates, particularly biomass derived carbohydrates and more specifically biomass (e.g., lignocellulosic biomass), to furfural-/HMF-ketone adducts for liquid hydrocarbon production under mild conditions.
FILED	Tuesday, November 08, 2011
APPL NO	13/883755
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/47 (20130101) C10G 3/48 (20130101) C10G 3/50 (20130101) Original (OR) Class C10G 2300/44 (20130101) C10G 2300/1011 (20130101) C10G 2300/1014 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101)
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Department of Veterans Affairs (DVA)

09486140 — Coherence gated doppler motion sensor and medical applications

US 09486140	Tang et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	University of Maryland, Baltimore (Baltimore, Maryland); University of Maryland, College Park (College Park, Maryland); St. Jude Medical (Westford, Massachusetts); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)	University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); St. Jude Medical (Westford, Massachusetts); University of Maryland, College Park (College Park, Maryland)
INVENTOR(S)	Cha-Min Tang (Radnor, Pennsylvania); Chia-Pin Liang (College Park, Maryland); Yu Chen (Greenbelt, Maryland); Ashraf Fouad (Baltimore, Maryland); Joseph Schmitt (Andover, Massachusetts); Nicholas Woolsey (Hudson, Massachusetts)
ABSTRACT	A motion sensor applicable to medical procedures includes a source of light with a wavelength bandwidth and an optical detector. A first optical coupler terminates in a first probe tip and couples the light into the first probe tip. A second optical coupler terminates in a second probe tip and directs onto the detector scattered light returning through the second probe tip. A presentation device outputs a signal that indicates motion in a target volume of a sample in a vicinity of the probe tips based on a Doppler shift of the scattered light. The volume depends on coherence distance determined by the bandwidth. In variations, the first and second tips are the same tip, a multimode fiber is included, the bandwidth is between 0.1% and 5% of a center wavelength, or the presentation device is a speaker, or some combination.
FILED	Thursday, August 08, 2013
APPL NO	13/962450
ART UNIT	2886 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0059 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/0084 (20130101) A61B 5/0088 (20130101) A61B 5/0261 (20130101) A61B 5/489 (20130101) A61B 5/7415 (20130101) Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 19/04 (20130101)
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09490420 — Polymer foam-based piezoelectric materials and method of manufacture

US 09490420	Zeng et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S)	Changchun Zeng (Tallahassee, Florida); Yan Li (Tallahassee, Florida)
ABSTRACT	Thermally stable piezoelectric polymer foams (ferroelectrets) with high piezoelectric activity for sensing and actuation. The invention further includes a method of fabricating such foams in an environmentally friendly manner.
FILED	Monday, August 17, 2015
APPL NO	14/827596
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/08 (20130101) H01L 41/39 (20130101) H01L 41/083 (20130101) H01L 41/193 (20130101) Original (OR) Class H01L 41/277 (20130101)
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Small Business Administration (SBA)

09488601 — Material erosion monitoring system and method

US 09488601	Ruege et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	PaneraTech, Inc. (Chantilly, Virginia)
ASSIGNEE(S)	PANERATECH, INC. (Chantilly, Virginia)
INVENTOR(S)	Alexander C. Ruege (Centerville, Virginia); Yakup Bayram (Falls Church, Virginia); Eric K. Walton (Columbus, Ohio)
ABSTRACT	Disclosed is an improved system and method to evaluate the status of a material. The system and method are operative to identify flaws and measure the erosion profile and thickness of different materials, including refractory materials, using electromagnetic waves. The system is designed to reduce a plurality of reflections, associated with the propagation of electromagnetic waves launched into the material under evaluation, by a sufficient extent so as to enable detection of electromagnetic waves of interest reflected from remote discontinuities of the material. Furthermore, the system and method utilize a configuration and signal processing techniques that reduce clutter and enable the isolation of electromagnetic waves of interest. Moreover, the launcher is impedance matched to the material under evaluation, and the feeding mechanism is designed to mitigate multiple reflection effects to further suppress clutter.
FILED	Wednesday, March 26, 2014
APPL NO	14/226102
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 21/0021 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 15/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/02 (20130101) Original (OR) Class
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09489813 — System for location in environment and identification tag

US 09489813	Beigel
FUNDED BY	Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Michael L. Beigel (Encinitas, California)
ASSIGNEE(S)
INVENTOR(S)	Michael L. Beigel (Encinitas, California)
ABSTRACT	A system for location of animals and/or objects in an environment includes a signal processing and signal generation system consisting of electromagnetic tags on animals (or other objects) in an environment (typically a three dimension outdoor natural environment) where the animals or objects are physically present at arbitrary locations, and an electro-magnetic signal generating, signal receiving, and signal processing system that can move through or in relation to the environment. The system can compute the location and identity of the animals or objects based on signals received from their associated tags, including the calculated location of the ID tags, which function as “Reader-Locators.” The calculated location is enhanced by information about the environment provided by maps, satellite photos, GPS, GIS and/or other data specific to the probability of the location of the animals or objects within certain regions of the environment. The system includes a physical and electromagnetic modeling operation that is interactive with the environmental information derived from the actual environment, either historically or in “real-time” as the monitoring process occurs.
FILED	Monday, October 06, 2008
APPL NO	12/287218
ART UNIT	2681 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/2417 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Department of Commerce (DOC)

09486179 — Multilayered phantom tissue test structure and fabrication process

US 09486179	Hwang et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Jeeseong Hwang (Gaithersburg, Maryland); Christopher Stafford (Ijamsville, Maryland); Robert Chang (Gaithersburg, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Commerce The National Institute of Standards and Technology (Washington, District of Columbia)
INVENTOR(S)	Jeeseong Hwang (Gaithersburg, Maryland); Christopher Stafford (Ijamsville, Maryland); Robert Chang (Gaithersburg, Maryland)
ABSTRACT	A multilayered optical tissue phantom fabrication approach and inherently produced test target structure which address the issues of of optical conformity known in the art by controlling the formation of micrometer scale monolayers embedded with light-scattering microspheres.
FILED	Thursday, September 05, 2013
APPL NO	14/019128
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/7221 (20130101) A61B 6/583 (20130101) Original (OR) Class Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/263 (20130101) B32B 38/10 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02072 (20130401) G01B 9/02091 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24612 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

09488650 — Detection of conductive polymer-labeled analytes

US 09488650	Alocilja et al.
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
ASSIGNEE(S)	BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
INVENTOR(S)	Evangelyn C. Alocilja (East Lansing, Michigan); Emma Setterington (Lansing, Michigan)
ABSTRACT	The disclosure relates to the detection of analytes (e.g., biological pathogens such as bacteria or viruses) using a conductive polymer label. The disclosed detection system utilizing the conductive polymer label generally involves the formation of an analyte conjugate between the target analyte and a conductive polymer moiety conjugated to the target analyte. The conductive polymer portion of the analyte conjugate is electrically activated to form an electrically activated analyte conjugate having an increased electrical conductivity relative to the analyte conjugate as originally formed. The electrically activated analyte conjugate can then be detected by any suitable means, such as by conductimetric or electrochemical detection.
FILED	Monday, September 08, 2014
APPL NO	14/480162
ART UNIT	1677 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) G01N 33/54326 (20130101) G01N 33/54333 (20130101) G01N 33/56911 (20130101) G01N 33/56916 (20130101) Original (OR) Class G01N 33/56983 (20130101) G01N 2333/245 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0054 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of the Interior (DOI)

09486747 — Nanocomposite membranes with advanced antifouling properties under visible light irradiation

US 09486747	Deng et al.
FUNDED BY	Department of the Interior (DOI) U.S. Geological Survey (USGS) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Baolin Deng (Columbia, Missouri); Jun Yin (Columbia, Missouri)
ASSIGNEE(S)	The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Baolin Deng (Columbia, Missouri); Jun Yin (Columbia, Missouri)
ABSTRACT	Nitrogen doped TiO2 (N—TiO2) is used to fabricate Poly(vinyledene fluoride) (PVDF)/N—TiO2 mixed matrix hollow fiber membranes (HFMs) through a phase inversion method to improve filtration efficiencies and antifouling properties. The membranes performances were evaluated based on the water permeability, humic acid (HA) rejection and antifouling properties. Resulting membranes showed brown color and improved hydrophilicity, especially under light irradiation. When compared to original PVDF and PVDF/P25 membrane, mixed matrix membranes containing N—TiO2 nanoparticles (NPs) showed clear photocatalytic activities under visible light irradiation. Also, membrane performance assessments indicated that PVDF/N—TiO2 membranes possessed enhanced water flux, similar HA rejection (e.g., above 96%) and improved fouling resistance with PVDF membranes as a control. The results demonstrate the potential of the suggested methodology for development of membranes with improved water permeability and superior antifouling properties based on photo-degradation processes and photo-induced hydrophilicity enhancement driven by solar light as a renewable energy source.
FILED	Friday, August 07, 2015
APPL NO	14/821390
ART UNIT	1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 65/08 (20130101) B01D 69/02 (20130101) B01D 69/08 (20130101) Original (OR) Class B01D 69/148 (20130101) B01D 71/34 (20130101) B01D 2321/343 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Geospatial Intelligence Agency (NGA)

09491389 — Focal plane array processing method and apparatus

US 09491389	Kelly et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) National Geospatial Intelligence Agency (NGA)
APPLICANT(S)	Michael Kelly (North Reading, Massachusetts); Brian Tyrrell (Brookline, New Hampshire); Curtis Colonero (Shrewsbury, Massachusetts); Robert Berger (Lexinton, Massachusetts); Kenneth Schultz (Lexington, Massachusetts); James Wey (Arlington, Massachusetts); Daniel Mooney (Dracut, Massachusetts); Lawrence Candell (Arlington, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Michael Kelly (North Reading, Massachusetts); Brian Tyrrell (Brookline, New Hampshire); Curtis Colonero (Shrewsbury, Massachusetts); Robert Berger (Lexinton, Massachusetts); Kenneth Schultz (Lexington, Massachusetts); James Wey (Arlington, Massachusetts); Daniel Mooney (Dracut, Massachusetts); Lawrence Candell (Arlington, Massachusetts)
ABSTRACT	A digital focal plane array includes an all-digital readout integrated circuit in combination with a detector array. The readout circuit includes unit cell electronics, orthogonal transfer structures, and data handling structures. The unit cell electronics include an analog to digital converter. Orthogonal transfer structures enable the orthogonal transfer of data among the unit cells. Data handling structures may be configured to operate the digital focal plane array as a data encryptor/decipherer. Data encrypted and deciphered by the digital focal plane array need not be image data.
FILED	Friday, March 21, 2014
APPL NO	14/221429
ART UNIT	2878 — Optics
CURRENT CPC	Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 20/0021 (20130101) G11B 20/00086 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/12 (20130101) H04L 9/0637 (20130101) H04L 2209/12 (20130101) H04L 2209/805 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 5/378 (20130101) Original (OR) Class H04N 5/772 (20130101) H04N 5/913 (20130101) H04N 21/4223 (20130101) H04N 21/4408 (20130101) H04N 2005/91364 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Security Agency (NSA)

09490188 — Compute intensive module packaging

US 09490188	Arvelo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Security Agency (NSA) Maryland Procurement Office (MPO)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Amilcar R. Arvelo (Poughkeepsie, New York); Michael J. Ellsworth (Lagrangeville, New York); Eric J. McKeever (Poughkeepsie, New York); Thong N. Nguyen (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York)
ABSTRACT	A package for a multi-chip module includes a top cold plate and a bottom plate whose perimeters are in thermal communication so the plates together completely encase the module except for a connector passing through the bottom plate. The cold plate has copper tubing pressed into a groove formed in a serpentine pattern. The perimeter of the cold plate has thermal conduction fins which mate with thermal conduction slots in the perimeter of the bottom plate. Thermal interface material is disposed in gaps between the plates and chips on the module, the gaps having dimensions controlled by support ribs of plates which abut the module substrate. The cold plate is used on the hottest side of the module, e.g., the side having computationally-intensive chips such as ASICs. A densely packed array of these packages can be used in a central electronic complex drawer with a shared coolant circulation system.
FILED	Friday, September 12, 2014
APPL NO	14/485225
ART UNIT	2896 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/34 (20130101) H01L 23/42 (20130101) H01L 23/367 (20130101) Original (OR) Class H01L 23/473 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/30 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

09488392 — Thin film-based compact absorption cooling system

US 09488392	Moghaddam
FUNDED BY
APPLICANT(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	Saeed Moghaddam (Gainesville, Florida)
ABSTRACT	An exchanger for absorption or desorption of a refrigerant employs an ultra thin film (UTF) of a refrigerant solution constrained to a channel by a permeable membrane. The UTF has a thickness of about 250 μm or less. The permeable membrane can be a nanostructured membrane, such as a membrane of nanofibers. The exchangers can be employed in an absorption refrigeration system (ARS) that use waste heat or solar heaters permitting the ARS to be less than one tenth the volume and mass of a conventional ARS.
FILED	Thursday, October 25, 2012
APPL NO	14/353391
ART UNIT	3744 — Material and Article Handling
CURRENT CPC	Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 15/00 (20130101) Original (OR) Class F25B 17/02 (20130101) F25B 37/00 (20130101) F25B 2315/00 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 3/02 (20130101) F28D 21/0015 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/62 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09489534 — Multi-level security system for enabling secure file sharing across multiple security levels and method thereof

US 09489534	Hashii et al.
FUNDED BY
APPLICANT(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S)	Brant D. Hashii (Long Beach, California); Mark O. Scott (Escondido, California); Daniel R. Silverman (Hermosa Beach, California); Lee Wixtrom (La Palma, California); Jonathan Tester (Encinitas, California); Steve A. Brown (Los Angeles, California)
ABSTRACT	A multi-level security system includes a storage medium partitionable into a plurality of partitions, a file system coupleable to the plurality of partitions, and a plurality of enclaves. Each enclave is assigned a security classification level. Each enclave resides in a different storage partition of the storage medium. Data stored on the storage medium is cryptographically separated at rest on a per-enclave basis. Cryptographic separation occurs at the disk block level, allowing individual blocks to be read and decrypted. The system also includes a reference monitor that enforces a system security policy that governs access to information between the enclaves. The reference monitor allows an enclave having a first classification level to securely read-down to an enclave having a second classification level lower than the first classification level and to write to another enclave having the first classification level.
FILED	Thursday, October 23, 2014
APPL NO	14/522447
ART UNIT	2433 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 17/30 (20130101) G06F 17/30203 (20130101) G06F 21/62 (20130101) G06F 21/6218 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 08, 2016.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2016/fedinvent-patents-20161108.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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