FedInvent™ Patents
Patent Details for Tuesday, November 15, 2016
This page was updated on Monday, March 27, 2023 at 04:54 AM GMT
Department of Health and Human Services (HHS)
US 09491934 | Cox, III et al. |
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FUNDED BY |
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APPLICANT(S) | George Norbert Cox, III (Louisville, Colorado); Casey Christopher Case (San Mateo, California); Stephen P. Eisenberg (Boulder, Colorado); Eric Edward Jarvis (Boulder, Colorado); Sharon Kaye Spratt (Vacaville, California) |
ASSIGNEE(S) | Sangamo BioSciences, Inc. (Richmond, California) |
INVENTOR(S) | George Norbert Cox, III (Louisville, Colorado); Casey Christopher Case (San Mateo, California); Stephen P. Eisenberg (Boulder, Colorado); Eric Edward Jarvis (Boulder, Colorado); Sharon Kaye Spratt (Vacaville, California) |
ABSTRACT | The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins. |
FILED | Monday, May 23, 2011 |
APPL NO | 13/068878 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 2217/05 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 48/005 (20130101) Peptides C07K 14/47 (20130101) C07K 14/52 (20130101) C07K 2319/00 (20130101) C07K 2319/71 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/67 (20130101) C12N 15/85 (20130101) C12N 15/8216 (20130101) C12N 2830/002 (20130101) C12N 2830/005 (20130101) C12N 2830/008 (20130101) C12N 2830/85 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/66 (20130101) C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492068 | Papania et al. |
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APPLICANT(S) | Mark J. Papania (Lilburn, Georgia); James J. Barry (Hanover, New Hampshire); Mark C. Bagley (Grafton, New Hampshire); Eric M. Friets (Norwich, Vermont); Darin A. Knaus (Norwich, Vermont) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia); CREARE LLC (Hanover, New Hampshire) |
INVENTOR(S) | Mark J. Papania (Lilburn, Georgia); James J. Barry (Hanover, New Hampshire); Mark C. Bagley (Grafton, New Hampshire); Eric M. Friets (Norwich, Vermont); Darin A. Knaus (Norwich, Vermont) |
ABSTRACT | A nasal delivery device can include a nasal prong and an activation member. The nasal prong can comprises an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can be configured to detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent. |
FILED | Friday, June 03, 2011 |
APPL NO | 13/701992 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/04 (20130101) A61B 1/06 (20130101) A61B 1/233 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/00 (20130101) A61M 11/005 (20130101) A61M 11/007 (20140204) A61M 15/08 (20130101) A61M 15/0098 (20140204) A61M 16/0488 (20130101) A61M 2016/0024 (20130101) A61M 2016/0042 (20130101) A61M 2205/43 (20130101) A61M 2205/502 (20130101) A61M 2205/581 (20130101) A61M 2205/3365 (20130101) A61M 2205/3375 (20130101) A61M 2205/6036 (20130101) A61M 2205/6054 (20130101) A61M 2205/6063 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492083 | Rege et al. |
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APPLICANT(S) | VASOPTIC MEDICAL INC. (Baltimore, Maryland) |
ASSIGNEE(S) | VASOPTIC MEDICAL, INC. (Baltimore, Maryland) |
INVENTOR(S) | Abhishek Rege (Baltimore, Maryland); M. Jason Brooke (University Park, Maryland) |
ABSTRACT | Imaging various regions of the eye is important for both clinical diagnostic and treatment purposes as well as for scientific research. Diagnosis of a number of clinical conditions relies on imaging of the various tissues of the eye. The subject technology describes a method and apparatus for imaging of the back and/or front of the eye using multiple illumination modalities, which permits the collection of one or more of reflectance, spectroscopic, fluorescence, and laser speckle contrast images. |
FILED | Tuesday, September 15, 2015 |
APPL NO | 14/855329 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/12 (20130101) A61B 3/14 (20130101) Original (OR) Class A61B 3/0025 (20130101) A61B 3/0033 (20130101) A61B 3/0041 (20130101) A61B 3/0075 (20130101) A61B 3/0083 (20130101) A61B 3/0091 (20130101) A61B 3/152 (20130101) A61B 3/1208 (20130101) A61B 3/1233 (20130101) A61B 3/1241 (20130101) A61B 5/0013 (20130101) A61B 5/02007 (20130101) A61B 5/6803 (20130101) A61B 2560/0475 (20130101) Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492089 | Hielscher et al. |
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APPLICANT(S) | Andreas H. Hielscher (Brooklyn, New York); Michael Khalil (Hamden, Connecticut); Rajeev Dayal (Great Neck, New York); In-Kyong Kim (New York, New York); Hyun Keol Kim (River Edge, New Jersey) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Andreas H. Hielscher (Brooklyn, New York); Michael Khalil (Hamden, Connecticut); Rajeev Dayal (Great Neck, New York); In-Kyong Kim (New York, New York); Hyun Keol Kim (River Edge, New Jersey) |
ABSTRACT | The disclosed subject matter includes optical tomographic systems for acquiring and displaying dynamic data representing changes in a target tissue sample to external provocation. For example, the disclosed devices, methods and systems may be used for quantifying dynamic vascular changes caused by imposed blood pressure changes for diagnosing peripheral artery disease. |
FILED | Friday, November 11, 2011 |
APPL NO | 13/876861 |
ART UNIT | 3777 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0053 (20130101) A61B 5/0066 (20130101) Original (OR) Class A61B 5/0073 (20130101) A61B 5/02007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492098 | Davis et al. |
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FUNDED BY |
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APPLICANT(S) | LKC Technologies, Inc. (Gaithersburg, Maryland) |
ASSIGNEE(S) | LKC TECHNOLOGIES, INC. (Gaithersburg, Maryland) |
INVENTOR(S) | Charles Quentin Davis (Frederick, Maryland); Frank Hunleth (Rockville, Maryland) |
ABSTRACT | To assess visual system function, a device monitors electrical response to a visual stimulus. Stimulus generation includes controlling the timing of component flashes comprising the visual stimulus and modulating the timing between the visual stimulus and other device operations, including image acquisition and infrared flashes. Other stimulus generation includes controlling retinal illumination for sinusoidal, triangular, and square stimuli as well as nonlinear adjustments of stimulus luminance as a function of pupil area. Ease of use improvements includes operation with electrode arrays. Error condition monitoring includes determining the presence of: an eye's pupil; impedance between electrodes that monitor the electrical response; and undesirable levels of external light. |
FILED | Tuesday, January 28, 2014 |
APPL NO | 14/763275 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/12 (20130101) A61B 3/14 (20130101) A61B 3/112 (20130101) A61B 5/053 (20130101) A61B 5/0496 (20130101) Original (OR) Class A61B 2562/043 (20130101) A61B 2562/0257 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492100 | Neeman et al. |
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APPLICANT(S) | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (Rehovot, Israel) |
ASSIGNEE(S) | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (Rehovot, Israel) |
INVENTOR(S) | Michal Neeman (Mazkeret Batya, Israel); Moriel Vandsburger (Rehovot, Israel) |
ABSTRACT | The invention provides magnetic resonance imaging methods for detecting cardiac diseases including myocardial fibrosis. Specifically, the invention provides a magnetic resonance imaging (MRI) pulse sequence that could be used to perform magnetization transfer (MT) or chemical exchange saturation transfer (CEST) in the heart. |
FILED | Wednesday, April 02, 2014 |
APPL NO | 14/242965 |
ART UNIT | 3777 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/055 (20130101) Original (OR) Class A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5605 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492323 | Knox et al. |
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APPLICANT(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Wayne H. Knox (Pittsford, New York); Krystel R. Huxlin (Rush, New York) |
ABSTRACT | A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss. |
FILED | Tuesday, December 17, 2013 |
APPL NO | 14/109542 |
ART UNIT | 3769 — Optics |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/008 (20130101) A61F 9/00827 (20130101) A61F 9/00829 (20130101) Original (OR) Class A61F 2009/0087 (20130101) A61F 2009/00842 (20130101) A61F 2009/00851 (20130101) A61F 2009/00872 (20130101) A61F 2009/00897 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492385 | Needham |
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APPLICANT(S) | David Needham (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | David Needham (Durham, North Carolina) |
ABSTRACT | A liposome contains an active agent and has a gel-phase lipid bilayer membrane comprising phospholipid and a surface active agent. The phospholipids are the primary lipid source for the lipid bilayer membrane and the surface active agent is contained in the bilayer membrane in an amount sufficient to increase the percentage of active agent released at the phase transition temperature of the lipid bilayer, compared to that which would occur in the absence of the surface active agent. The surface active agent is present in the lipid bilayer membrane so as to not destabilize the membrane in the gel phase. |
FILED | Wednesday, December 10, 2008 |
APPL NO | 12/332144 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1271 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492405 | Wainer et al. |
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APPLICANT(S) | Irving W. Wainer (Washington, District of Columbia); Michel Bernier (Pikesville, Maryland); Lawrence Robert Toll (Redwood City, California); Lucita Arenas Jimenez (San Jose, California) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); SRI International (Menlo Park, California) |
INVENTOR(S) | Irving W. Wainer (Washington, District of Columbia); Michel Bernier (Pikesville, Maryland); Lawrence Robert Toll (Redwood City, California); Lucita Arenas Jimenez (San Jose, California) |
ABSTRACT | This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogs for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analog or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject. |
FILED | Thursday, March 10, 2011 |
APPL NO | 13/583206 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class A61K 31/137 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492408 | Leikauf |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | George Douglas Leikauf (Gibsonia, Pennsylvania) |
ABSTRACT | Methods are provided herein for treating an individual having a disease, disorder or condition affecting the lungs, wherein said disease, disorder, or condition of the lung is an acute lung injury. In specific embodiments, the acute lung injury is chemical induced acute lung injury (CIALI). In some embodiments, the methods are provided for treating or protecting a subject from chemical induced acute lung injury that include administering to the subject a therapeutically effective amount of a phosphatase located on chromosome 10 (PTEN) inhibitor such as N(9,10-dioxo-9,10-di-hydrophenanthren-2-yl)pivalamide (SF1670). In some embodiments, the method products a subject from CAILI or reduces CAILI that results from a subsequent exposure to a chemical that induces chemical induced acute lung injury. |
FILED | Thursday, October 23, 2014 |
APPL NO | 14/522522 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/055 (20130101) A61B 5/087 (20130101) A61B 5/0871 (20130101) A61B 5/4848 (20130101) A61B 5/14542 (20130101) A61B 10/02 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/164 (20130101) Original (OR) Class A61K 31/164 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492414 | Tavazoie et al. |
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APPLICANT(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
ASSIGNEE(S) | The Rockefeller University (New York, New York) |
INVENTOR(S) | Sohail Tavazoie (New York, New York); Jia M. Loo (New York, New York) |
ABSTRACT | The present invention discloses novel agents and methods for diagnosis and treatment of colon cancer. Also disclosed are related arrays, kits, and screening methods. |
FILED | Thursday, May 07, 2015 |
APPL NO | 14/706038 |
ART UNIT | 1674 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/197 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 31/513 (20130101) A61K 31/555 (20130101) A61K 31/4168 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7072 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492418 | Lee et al. |
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APPLICANT(S) | Yong-Hwan Lee (Baton Rouge, Louisiana); Jeong Do Kim (Baton Rouge, Louisiana) |
ASSIGNEE(S) | Board of Supervisors of Louisiana State University And Agricultural and Mechanical College (Baton Rouge, Louisiana) |
INVENTOR(S) | Yong-Hwan Lee (Baton Rouge, Louisiana); Jeong Do Kim (Baton Rouge, Louisiana) |
ABSTRACT | Compounds used to inhibit glycolytic pathway small molecule kinase 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB) are set forth; these inhibitors can be used in the treatment of certain diseases in which cells or tumors rely on glycolytic metabolism, such as many cancer cells. |
FILED | Wednesday, May 09, 2012 |
APPL NO | 13/467764 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/37 (20130101) A61K 31/222 (20130101) Original (OR) Class A61K 31/352 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492432 | Vavvas et al. |
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APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
INVENTOR(S) | Demetrios Vavvas (Boston, Massachusetts); Georgios Trichonas (Boston, Massachusetts); Joan W. Miller (Winchester, Massachusetts); Yusuke Murakami (Newton, Massachusetts) |
ABSTRACT | Provided are methods and compositions for maintaining the viability of photoreceptor cells and/or retinal pigment epithelial cells in a subject with an ocular disorder including, for example, age-related macular degeneration (AMD) (e.g., dry or neovascular AMD), retinitis pigmentosa (RP), or a retinal detachment. The viability of the photoreceptor cells and/or the retinal pigment epithelial cells can be preserved by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject having an eye with the ocular condition. The compositions, when administered, maintain the viability of the cells, thereby minimizing the loss of vision or visual function associated with the ocular disorder. |
FILED | Friday, November 06, 2015 |
APPL NO | 14/934810 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/40 (20130101) A61K 31/4178 (20130101) Original (OR) Class A61K 38/005 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492434 | Luesch et al. |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Hendrik Luesch (Gainesville, Florida); Brian Keith Law (Gainesville, Florida) |
ABSTRACT | The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as methods of modulating cellular proliferation processes, and methods of treating disease, disorders, and symptoms thereof. |
FILED | Friday, December 07, 2012 |
APPL NO | 14/363730 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/429 (20130101) Original (OR) Class A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 513/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492439 | Littman et al. |
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APPLICANT(S) | Dan Littman (New York, New York); Jun R. Huh (New York, New York); Wenwei Huang (Rockville, Maryland); Ruili Huang (Rockville, Maryland); Erika Elaine Englund (Washington, District of Columbia) |
ASSIGNEE(S) | New York University (New York, New York); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Dan Littman (New York, New York); Jun R. Huh (New York, New York); Wenwei Huang (Rockville, Maryland); Ruili Huang (Rockville, Maryland); Erika Elaine Englund (Washington, District of Columbia) |
ABSTRACT | Amido compounds are disclosed that have a formula represented by the following: and wherein n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease. |
FILED | Friday, March 11, 2011 |
APPL NO | 13/634073 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/33 (20130101) A61K 31/535 (20130101) A61K 31/4453 (20130101) A61K 31/4525 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 235/34 (20130101) C07C 235/36 (20130101) Heterocyclic Compounds C07D 211/06 (20130101) C07D 211/16 (20130101) C07D 307/52 (20130101) C07D 317/54 (20130101) C07D 317/60 (20130101) C07D 401/10 (20130101) C07D 403/14 (20130101) C07D 405/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492441 | DiSanto |
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APPLICANT(S) | Michael E. DiSanto (Burlington, New Jersey) |
ASSIGNEE(S) | |
INVENTOR(S) | Michael E. DiSanto (Burlington, New Jersey) |
ABSTRACT | Provided are methods of treating an overactive bladder in a patient which include: administering a Myosin II ATPase inhibitor compound; or administering an X group and Y group substituted (3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3b]quinolin-4-one) compound of Formula 1 or administering an X group and Y group substituted (3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3b]quinolin-4-one) compound of Formula II; or administering pharmaceutically-acceptable salts, racemic mixtures, enantiomers, or prodrugs of said compounds, useful in their active form as inhibitors of Myosin H ATPase related to over-active bladder. Optionally the compounds are administered intervesicularly into the bladder. Also provided are pharmaceutical compositions comprising said compounds useful in their active form, as methods of treating a patient suffering from an over-active bladder related to inhibition of Myosin II ATPase. These pharmaceutical compositions also may contain one or more other compounds useful in their active form, as methods of treating a patient suffering from an over-active bladder. |
FILED | Thursday, May 17, 2012 |
APPL NO | 14/118448 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class A61K 45/06 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 1/026 (20130101) Transmission H04B 1/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492450 | Qian et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Wei Qian (Pittsburgh, Pennsylvania); Bennett Van Houten (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to compositions and methods for reducing cell proliferation and/or promoting cell death by inhibiting Drp1. It is based, at least in part, on the discoveries that (i) Drp1 disruption-induced mitochondrial hyperfusion is functionally linked to the cell cycle regulation apparatus, so that Drp1 inhibition results in a disruption of the cell cycle and DNA aberrancies; (ii) inhibition of both Drp1 and ATR are synthetic lethal causing increased DNA damage and apoptotic cell death; and (iii) even in resistant cell lines, Drp1 inhibitor (e.g., mdivi-1) together with a second antiproliferative agent (e.g., cisplatin or carboplatin) act synergistically to promote apoptosis. Accordingly, the present invention provides for novel anticancer strategies. |
FILED | Thursday, May 08, 2014 |
APPL NO | 14/273218 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/555 (20130101) A61K 31/555 (20130101) A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 38/38 (20130101) A61K 38/38 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492470 | Kennedy |
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APPLICANT(S) | MIAMI UNIVERSITY (Oxford, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Michael A Kennedy (Oxford, Ohio) |
ABSTRACT | Elevated high mobility group A (HMGA) protein expression in human cancer cells, and especially human pancreatic cancer cells, is correlated with resistance to the chemotherapy agent gemcitabine. The present invention uses HMGA-targeted AT-rich phosphorothioate DNA (AT-sDNA) aptamers to suppress HMGA carcinogenic activity. Cell growth of human pancreatic cancer cells (AsPC-1 and Miapaca-2) transfected with AT-sDNA were monitored after treatment with gemcitabine. Significant increases in cell death in AT-sDNA transfected cells compared to non AT-rich sDNA treated cells were observed in both cell lines. The data indicates the potential use of HMGA targeted DNA aptamers to enhance chemotherapy efficacy in human cancer treatment, and in particular human pancreatic cancer treatment. |
FILED | Wednesday, November 25, 2015 |
APPL NO | 14/951887 |
ART UNIT | 1674 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/7068 (20130101) Original (OR) Class A61K 31/7068 (20130101) A61K 31/7088 (20130101) A61K 31/7125 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/315 (20130101) C12N 2320/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492477 | Yang |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Jian Yang (State College, Pennsylvania) |
ABSTRACT | In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises promoting cell differentiation or phenotype progression in a population of bone cells by providing a citrate-presenting composition to the population of bone cells. In some embodiments, the citrate-presenting composition is provided to the bone cells at a first stage of cell development selected to obtain a first cell differentiation or phenotype progression. Additionally, in some cases, a second citrate-presenting composition is further provided to the bone cells at a second stage of cell development selected to obtain a second cell differentiation or phenotype progression. |
FILED | Thursday, January 02, 2014 |
APPL NO | 14/146272 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/765 (20130101) A61K 31/785 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/12 (20130101) C08G 63/914 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0669 (20130101) C12N 2500/34 (20130101) C12N 2501/155 (20130101) C12N 2533/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492484 | Yeghiazarians et al. |
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APPLICANT(S) | Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Yerem Yeghiazarians (Burlingame, California); Jianqin Ye (San Francisco, California); Andrew Boyle (San Francisco, California); Kevin E. Healy (Berkeley, California); Amit K. Jha (Berkeley, California) |
ABSTRACT | Provided herein are compositions and methods for isolating and culturing cardiac progenitor cells, and for improved transplantation. |
FILED | Thursday, September 26, 2013 |
APPL NO | 14/038571 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 2533/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492485 | Saeki et al. |
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APPLICANT(S) | Kumiko Saeki (Tokyo, Japan); Akira Yuo (Tokyo, Japan); Miwako Nishio (Tokyo, Japan); Masako Kawasaki (Tokyo, Japan); Koichi Saeki (Ibaraki, Japan); Mamoru Hasegawa (Ibaraki, Japan) |
ASSIGNEE(S) | ID Pharma Co., Ltd. (Ibaraki, Japan); National Center for Global Health and Medicine (Tokyo, Japan) |
INVENTOR(S) | Kumiko Saeki (Tokyo, Japan); Akira Yuo (Tokyo, Japan); Miwako Nishio (Tokyo, Japan); Masako Kawasaki (Tokyo, Japan); Koichi Saeki (Ibaraki, Japan); Mamoru Hasegawa (Ibaraki, Japan) |
ABSTRACT | Provided are a method of producing brown adipocytes from pluripotent stem cells, a method of producing cell aggregates as an intermediate product thereof, pluripotent stem cell-derived cell aggregates and pluripotent stem cell-derived brown adipocytes produced by these methods, and cell therapy using the pluripotent stem cell-derived brown adipocytes. In the method of producing brown adipocytes from pluripotent stem cells, cell aggregates are produced from pluripotent stem cells by a method including the step (A), and brown adipocytes are prepared from the cell aggregates by a method including the step (B). The step (A) is a step of producing cell aggregates by non-adhesive culture of pluripotent stem cells in serum-free environment in the presence of a hematopoietic cytokine, and the step (B) is a step of producing brown adipocytes by adhesion culture of the cell aggregates in the presence of a hematopoietic cytokine. |
FILED | Thursday, April 26, 2012 |
APPL NO | 14/113997 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/35 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 2501/26 (20130101) C12N 2501/105 (20130101) C12N 2501/155 (20130101) C12N 2501/165 (20130101) C12N 2501/2306 (20130101) C12N 2506/45 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492503 | Whitsett et al. |
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FUNDED BY |
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APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
INVENTOR(S) | Jeffrey A. Whitsett (Cincinnati, Ohio); Machiko Ikegami (Cincinnati, Ohio) |
ABSTRACT | Surfactant protein D (SP-D) is a member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the lung. Described herein are methods and compositions for the treatment of disorders associated with lung injury, including methods and compositions for the treatment of bronchopulmonary disorder (BPD). |
FILED | Thursday, October 24, 2013 |
APPL NO | 14/062682 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/395 (20130101) A61K 38/395 (20130101) A61K 38/1732 (20130101) Original (OR) Class A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492504 | Leisk et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | Gary G. Leisk (Wilmington, Massachusetts); Tim Jia-Ching Lo (Medford, Massachusetts); Lei Li (Beijing, China PRC); Evangelia Bellas (Somerville, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
ABSTRACT | The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection). In some embodiments, the composition described herein comprises a compressed silk fibroin matrix, which can expand upon injection into the tissue and retain its original expanded volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation. |
FILED | Friday, November 09, 2012 |
APPL NO | 14/357420 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1767 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) A61L 27/3604 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/34 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492510 | Potter et al. |
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FUNDED BY |
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APPLICANT(S) | St. Jude Children's Research Hospital (Memphis, Tennessee); The University of North Carolina (Chapel Hill, North Carolina) |
ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee); The University of North Carolina (Chapel Hill, North Carolina) |
INVENTOR(S) | Philip M. Potter (Memphis, Tennessee); Monika Weirdl (Memphis, Tennessee); Matthew R. Redinbo (Chapel Hill, North Carolina) |
ABSTRACT | Polynucleotides encoding a secreted mutant human carboxylesterase enzyme and polypeptides encoded by the polynucleotides which are capable of metabolizing a prodrug and inactive metabolites thereof to active drug are provided. Compositions and methods for sensitizing cells to a prodrug agent, inhibiting cell growth, treating drug addiction, and facilitating the metabolism of an organophosphate with this enzyme are also provided. In addition, a screening assay for identification of drugs activated by this enzyme is described. |
FILED | Tuesday, February 03, 2015 |
APPL NO | 14/612714 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/18 (20130101) Enzymes C12Y 301/01001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492533 | Friedman et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Harvey Friedman (Merion, Pennsylvania); Elizabeth E. Zumbrun (Middletown, Maryland); Fushan Wang (Broomall, Pennsylvania) |
ABSTRACT | This invention provides methods of treating, suppressing, inhibiting, reducing an incidence, reducing the pathogenesis of, ameliorating the symptoms of, or ameliorating the secondary symptoms of a primary or recurring Herpes Simplex Virus (HSV) infection, or prolonging the latency to a relapse of an HSV infection, and disorders and symptoms associated with same and inducing an anti-HSV immune response in a subject comprising the step of contacting the subject with a composition comprising a mutant HSV strain comprising an inactivating mutation in a Us8 gene, followed by a second contacting with the composition. |
FILED | Tuesday, December 16, 2014 |
APPL NO | 14/572004 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16622 (20130101) C12N 2710/16634 (20130101) C12N 2710/16661 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492536 | Offner et al. |
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APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Halina Offner (Portland, Oregon); Patricia D. Hurn (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon); Gregory G. Burrows (Portland, Oregon) |
ABSTRACT | Two-domain MHC polypeptides are useful for modulating activities of antigen-specific T-cells, including for modulating pathogenic potential and effects of antigen-specific T-cells. Exemplary MHC class II-based recombinant T-cell ligands (RTLs) of the invention include covalently linked β1 and α1 domains, and MHC class I-based molecules that comprise covalently linked α1 and α2 domains. These polypeptides may also include covalently linked antigenic determinants, toxic moieties, and/or detectable labels. The disclosed polypeptides can be used to target antigen-specific T-cells, and are useful, among other things, to detect and purify antigen-specific T-cells, to induce or activate T-cells, to modulate T-cell activity, including by regulatory switching of T-cell cytokine and adhesion molecule expression, to treat conditions mediated by antigen-specific T-cells, including treatment and/or prevention of central nervous system damage relating to stroke. |
FILED | Friday, June 05, 2015 |
APPL NO | 14/732145 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/0005 (20130101) A61K 39/385 (20130101) Original (OR) Class A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 2039/605 (20130101) A61K 2039/627 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492538 | Clarke et al. |
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APPLICANT(S) | Michael F. Clarke (Ann Arbor, Michigan); Sean J. Morrison (Ann Arbor, Michigan); Max S. Wicha (Ann Arbor, Michigan); Muhammad Al-Hajj (Cambridge, Massachusetts) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Michael F. Clarke (Ann Arbor, Michigan); Sean J. Morrison (Ann Arbor, Michigan); Max S. Wicha (Ann Arbor, Michigan); Muhammad Al-Hajj (Cambridge, Massachusetts) |
ABSTRACT | A small percentage of cells within an established tumor have the properties of stem cells. These solid tumor stem cells give rise both to more tumor stem cells and to the majority of cells in the tumor that have lost the capacity for extensive proliferation and the ability to give rise to new tumors. The solid tumor heterogeneity reflects the presence of tumor cell progeny arising from a solid tumor stem cell. This discovery is the basis for solid tumor stem cell compositions, methods for distinguishing functionally different populations of tumor cells, methods for using these tumor cell populations for studying the effects of therapeutic agents on tumor growth, and methods for identifying and testing novel anti-cancer therapies directed to solid tumor stem cells. |
FILED | Friday, June 10, 2005 |
APPL NO | 11/150524 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) Original (OR) Class A61K 2039/505 (20130101) A61K 2039/5152 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/71 (20130101) C07K 14/705 (20130101) C07K 14/70585 (20130101) C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2863 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0695 (20130101) C12N 2501/42 (20130101) C12N 2503/00 (20130101) C12N 2503/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57492 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492544 | Hawiger et al. |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Jack J. Hawiger (Nashville, Tennessee); Jozef Zienkiewicz (Nashville, Tennessee) |
ABSTRACT | The present invention relates to compositions and methods for treating autoimmune, microbial, metabolic, neoplastic, and posttraumatic diseases mediated by inflammation in a subject. Compositions and methods including at least one importin beta-selective nuclear transport modifier (NTM) and/or at least one importin alpha-selective NTM, and/or at least one importin alpha-specific NTM, and/or at least one inhibitor of importin alpha and importin beta complex formation may be administered to a subject to modulate the transport of transcription factors, mediated by nuclear import adaptors, into the nucleus of a cell resulting in a decrease or abrogation of inflammation. |
FILED | Friday, April 11, 2014 |
APPL NO | 14/251135 |
ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 38/12 (20130101) A61K 38/16 (20130101) A61K 38/16 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/50 (20130101) C07K 14/4702 (20130101) C07K 2319/00 (20130101) C07K 2319/09 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492554 | Arya et al. |
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FUNDED BY |
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APPLICANT(S) | Clemson University Research Foundation (CURF) (Anderson, South Carolina) |
ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
INVENTOR(S) | Dev P. Arya (Greenville, South Carolina); Nihar Ranjan (Clemson, South Carolina); Sunil Kumar (Clemson, South Carolina) |
ABSTRACT | Disclosed herein are compounds, compositions and methods related to viral inhibition. In some forms, the compounds, compositions and methods are related to binding RNA. |
FILED | Monday, May 04, 2015 |
APPL NO | 14/703549 |
ART UNIT | 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48061 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492564 | Bigner et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina); The United States of America as represented by the Secretary, Department of Health and Human Service (Washington, District of Columbia) |
ASSIGNEE(S) | Duke University (Durham, North Carolina); The United States of America, as represented by the Secretary of Health and Human Services, National Institutes of Health (Washington, District of Columbia) |
INVENTOR(S) | Darell Bigner (Mebane, North Carolina); Chien-Tsun Kuan (Cary, North Carolina); Ira H. Pastan (Potomac, Maryland); Charles Peagram (Durham, North Carolina) |
ABSTRACT | We tested the in vitro and in vivo efficacy of a recombinant bispecific immunotoxin that recognizes both EGFRwt and tumor-specific EGFRvIII receptors. A single chain antibody was cloned from a hybridoma and fused to toxin, carrying a C-terminal peptide which increases retention within cells. The binding affinity and specificity of the recombinant bispecific immunotoxin for the EGFRwt and the EGFRvIII proteins was measured. In vitro cytotoxicity was measured. In vivo activity of the recombinant bispecific immunotoxin was evaluated in subcutaneous models and compared to that of an established monospecific immunotoxin. In our preclinical studies, the bispecific recombinant immunotoxin, exhibited significant potential for treating brain tumors. |
FILED | Tuesday, May 06, 2014 |
APPL NO | 14/270836 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 47/48484 (20130101) Original (OR) Class A61K 47/48561 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/2863 (20130101) C07K 2317/56 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2317/624 (20130101) C07K 2319/04 (20130101) C07K 2319/55 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492569 | Nishimura et al. |
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FUNDED BY |
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APPLICANT(S) | Stephen Nishimura (Mill Valley, California); Jianlong Lou (San Bruno, California); Jody Lynn Baron (Mill Valley, California); James Marks (Kensington, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Stephen Nishimura (Mill Valley, California); Jianlong Lou (San Bruno, California); Jody Lynn Baron (Mill Valley, California); James Marks (Kensington, California) |
ABSTRACT | Provided herein are antibodies with high affinity for the β8 subunit of αvβ8. |
FILED | Friday, August 17, 2012 |
APPL NO | 14/239124 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2207/15 (20130101) A01K 2217/075 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/00 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 14/70546 (20130101) C07K 16/2839 (20130101) C07K 2317/24 (20130101) C07K 2317/30 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492571 | Gray et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts Medical School (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Brian D. Gray (Malvern, Pennsylvania); Mary Rusckowski (Southborough, Massachusetts); Koon Y. Pak (Malvern, Pennsylvania) |
ABSTRACT | The invention relates to novel multi-modality probes for imaging, tracking and analyzing stem cells and related biological samples, and methods of preparation and use thereof. The molecular probes of the invention are constructed, for example, by utilizing (a) the high selectivity of long hydrocarbon chains for binding to plasma membranes of cells, (b) a near-infrared (NIR) dye for optical imaging, and (c) a radionuclide for PET or SPECT imaging. The in vitro and in vivo data of the optical and radiolabeled probes demonstrated their utility for detecting the presence of stem cells with multiple imaging modalities. |
FILED | Monday, May 27, 2013 |
APPL NO | 14/400757 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 51/0446 (20130101) A61K 51/0478 (20130101) A61K 51/0482 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 209/14 (20130101) C07D 209/20 (20130101) C07D 403/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492663 | Roy et al. |
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FUNDED BY |
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APPLICANT(S) | Second Sight Medical Products, Inc. (San Fernando, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Arup Roy (Valencia, California); Pishoy Maksy (Newport Beach, California); Chunhong Zhou (Encinitas, California); Kelly H McClure (Simi Valley, California); Robert J Greenberg (Los Angeles, California); Matthew J McMahon (Washington, District of Columbia); Avraham I Caspi (Rehovot, Israel) |
ABSTRACT | A method of editing a video configuration file downloadable to or from a video processing unit of a fitting system for a visual prosthesis is shown. The visual prosthesis has a plurality of electrodes and the video configuration file defines mapping of a video signal captured from a camera of the visual prosthesis to an electrical signal for the electrodes. The editing controls a brightness map for an individual electrode or electrode groups, together with a temporal stimulation pattern to which an individual electrode or electrode groups are assigned. A related computer-operated system is also disclosed. |
FILED | Friday, February 21, 2014 |
APPL NO | 14/186260 |
ART UNIT | 3766 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/3605 (20130101) A61N 1/36046 (20130101) Original (OR) Class A61N 1/37235 (20130101) A61N 1/37247 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4661 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492670 | Mech et al. |
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FUNDED BY |
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APPLICANT(S) | Brian Mech (Stevenson Ranch, California); Robert J. Greenberg (Los Angeles, California); Honggang Jiang (Valencia, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Brian Mech (Stevenson Ranch, California); Robert J. Greenberg (Los Angeles, California); Honggang Jiang (Valencia, California) |
ABSTRACT | An implantable micro-miniature device is disclosed. The device comprises a thin hermetic insulating coating and at least one thin polymer or metal secondary coating over the hermetic insulating layer in order to protect the insulating layer from the erosive action of body fluids or the like. In one embodiment the insulating layer is ion beam assisted deposited (IBAD) alumina and the secondary coating is a parylene polymer. The device may be a small electronic device such as a silicon integrated circuit chip. The thickness of the insulating layer may be ten microns or less and the thickness of the secondary layer may be between about 0.1 and about 15 microns. |
FILED | Thursday, October 25, 2007 |
APPL NO | 11/923933 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/372 (20130101) Original (OR) Class A61N 1/375 (20130101) A61N 1/37205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492781 | Galbraith et al. |
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FUNDED BY |
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APPLICANT(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
ASSIGNEE(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
INVENTOR(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
ABSTRACT | Lightweight, small, portable devices and methods are disclosed that provide oxygen-enriched air using an ultra rapid adsorption cycle based on advanced molecular sieve materials. |
FILED | Friday, October 17, 2014 |
APPL NO | 14/516919 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 2/54 (20130101) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/22 (20130101) A61L 9/14 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/10 (20130101) A61M 16/101 (20140204) A61M 35/00 (20130101) A61M 2205/8206 (20130101) A61M 2205/8237 (20130101) A61M 2205/8262 (20130101) A61M 2209/086 (20130101) Separation B01D 53/047 (20130101) Original (OR) Class B01D 53/053 (20130101) B01D 53/0446 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2253/116 (20130101) B01D 2256/12 (20130101) B01D 2257/40 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/78 (20130101) Pipe-line Systems; Pipe-lines F17D 3/01 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492870 | Kaplowitz et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel Kaplowitz (Harrington Park, New Jersey); R. Jason Jouet (Indian Head, Maryland); Michael R. Zachariah (Potomac, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Daniel Kaplowitz (Harrington Park, New Jersey); R. Jason Jouet (Indian Head, Maryland); Michael R. Zachariah (Potomac, Maryland) |
ABSTRACT | Low temperature gas-phase methods for the preparation of faceted aluminum crystals are disclosed. |
FILED | Friday, September 14, 2012 |
APPL NO | 13/619017 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0018 (20130101) B22F 1/0085 (20130101) B22F 1/0088 (20130101) B22F 1/0088 (20130101) B22F 9/24 (20130101) Original (OR) Class B22F 9/30 (20130101) B22F 2001/0037 (20130101) B22F 2201/03 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Alloys C22C 21/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493022 | Tan et al. |
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FUNDED BY |
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APPLICANT(S) | Christine P. Tan (Singapore, Singapore); David M. Lin (Ithaca, New York); Harold G. Craighead (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Christine P. Tan (Singapore, Singapore); David M. Lin (Ithaca, New York); Harold G. Craighead (Ithaca, New York) |
ABSTRACT | An apparatus for forming an array of deposits on a substrate is disclosed. The apparatus may include a stencil capable of releasable attached to the substrate and having an array of openings and at least one alignment mark. The apparatus may further include a high throughput deposition printer aligned with the stencil to form an array of deposits on the substrate. The array of deposits may be aligned with the array of openings through the at least one alignment mark and an optional alignment device. Methods of manufacturing the stencil and using it to generate multiplexed or combinatorial arrays are also disclosed. |
FILED | Thursday, August 05, 2010 |
APPL NO | 13/389113 |
ART UNIT | 2854 — Printing/Measuring and Testing |
CURRENT CPC | Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/006 (20130101) Original (OR) Class Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00031 (20130101) B81C 2201/0184 (20130101) B81C 2201/0187 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493089 | Shin et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents Of The University Of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Kang G. Shin (Ann Arbor, Michigan); Eugene Kim (Ann Arbor, Michigan) |
ABSTRACT | An efficient way of predicting the power requirements of electric vehicles is proposed based on a history of vehicle power consumption, speed and acceleration as well as road information. By using this information and the operator's driving pattern, a model extracts the vehicles history of speed and acceleration, which in turn enables the prediction of the vehicle's future power requirements. That is, the power requirement prediction is achieved by combining a real-time power requirement model and the estimation of vehicle's acceleration and speed. |
FILED | Tuesday, March 24, 2015 |
APPL NO | 14/666369 |
ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 3/12 (20130101) B60L 11/1851 (20130101) Original (OR) Class B60L 15/2045 (20130101) B60L 2240/12 (20130101) B60L 2240/14 (20130101) B60L 2240/642 (20130101) B60L 2260/44 (20130101) B60L 2260/54 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) H01M 2220/20 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/00 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/72 (20130101) Y02T 10/645 (20130101) Y02T 10/705 (20130101) Y02T 10/7005 (20130101) Y02T 10/7283 (20130101) Y02T 10/7291 (20130101) Y02T 90/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493420 | Peyton et al. |
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FUNDED BY |
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APPLICANT(S) | David H. Peyton (Portland, Oregon); Steven Burgess (Tualatin, Oregon) |
ASSIGNEE(S) | Portland State University (Portland, Oregon) |
INVENTOR(S) | David H. Peyton (Portland, Oregon); Steven Burgess (Tualatin, Oregon) |
ABSTRACT | This disclosure provides a new class of compounds referred to as “reversed chloroquines” (RCQs), which are highly effective against CQR and CQS malaria parasites. RCQs are hybrid molecules, which include an antimalarial quinoline analog (such as chloroquine) moiety and a CQR reversal moiety. Exemplary RCQ chemical structures are provided. Also provided are pharmaceutical compositions including the disclosed RCQ compounds, and methods of using such compounds and compositions for the treatment of malaria and inhibition of CQR or CQS Plasmodium sp. (such as P. falciparum). |
FILED | Thursday, July 25, 2013 |
APPL NO | 13/951340 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/496 (20130101) A61K 31/551 (20130101) A61K 31/4706 (20130101) A61K 31/4709 (20130101) A61K 31/5415 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 215/44 (20130101) C07D 215/46 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/12 (20130101) C07D 409/14 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493436 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Zhong-Yin Zhang (Carmel, Indiana); Yantao He (Indianapolis, Indiana); Li-Fan Zeng (Indianapolis, Indiana) |
ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
INVENTOR(S) | Zhong-Yin Zhang (Carmel, Indiana); Yantao He (Indianapolis, Indiana); Li-Fan Zeng (Indianapolis, Indiana) |
ABSTRACT | A variety of benzofurans and indole derivatives some with an alkynyl linker are disclosed herein. These compounds are not highly charged at physiological pH and have good bioavailability characteristics. These compounds exhibit selective or at least preferential affinity for the active sites of various sub-sets of protein tyrosine phosphatases. Some of these compounds are excellent inhibitors of Mycobacterium protein tyrosine phosphatase B (mPTPB) a protein tyrosine phosphatase expressed in Mycobacterium tuberculosis and characterized as a virulence factor in the causal agent of tuberculosis. Accordingly, many of these compounds and pharmaceutically acceptable salts thereof are useful for the treatment of diseases such as tuberculosis. |
FILED | Wednesday, April 25, 2012 |
APPL NO | 14/114077 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 209/42 (20130101) C07D 307/80 (20130101) Original (OR) Class C07D 307/84 (20130101) C07D 401/12 (20130101) C07D 405/12 (20130101) C07D 407/06 (20130101) C07D 407/12 (20130101) C07D 409/06 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493439 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky) |
ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
INVENTOR(S) | Kyung-Bo Kim (Lexington, Kentucky); Vinod Kasam (Malden, Massachusetts); Wooin Lee (Seoul, South Korea); Dong-Eun Kim (Seoul, South Korea); Zach Miller (Madison, Wisconsin); Chang-Guo Zhan (Lexington, Kentucky); Do-Min Lee (Lexington, Kentucky) |
ABSTRACT | Compounds of formula (I) are useful for inhibiting a proteasome in a cell. Compounds, pharmaceutical compositions and methods of use are provided herein. |
FILED | Tuesday, April 07, 2015 |
APPL NO | 14/680553 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4155 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 403/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493464 | Roush et al. |
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FUNDED BY |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | William R. Roush (Jupiter, Florida); Ronald Rahaim (Palm Beach Gardens, Florida); Mathieu Bibian (Creissels, France) |
ABSTRACT | The invention provides compounds that inhibit the degradation of Wee1. The compounds of the present invention are generally N-((1H-benzo[d]imidazol-2-yl)methyl)-9H-purin-6-amines. Compounds of the invention can be used for treatment of malconditions in patients for which inhibition of Wee1 is medically indicated, for example cancer, Alzheimer's, neurological disorders, psychiatric disorders, or inflammation-related disorders. |
FILED | Tuesday, February 26, 2013 |
APPL NO | 14/381151 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 473/16 (20130101) C07D 473/32 (20130101) Original (OR) Class C07D 473/34 (20130101) C07D 519/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493465 | Evans et al. |
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FUNDED BY |
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APPLICANT(S) | Gary Brian Evans (Normandale, New Zealand); Alistair Ian Longshaw (Thorndon, New Zealand); Vern L. Schramm (New Rochelle, New York); Peter Charles Tyler (Northland, New Zealand) |
ASSIGNEE(S) | Victoria Link Limited (Wellington, New Zealand); Albert Einstein College of Medicine, Inc. (Bronx, New York) |
INVENTOR(S) | Gary Brian Evans (Normandale, New Zealand); Alistair Ian Longshaw (Thorndon, New Zealand); Vern L. Schramm (New Rochelle, New York); Peter Charles Tyler (Northland, New Zealand) |
ABSTRACT | The present invention relates to 3-hydroxypyrrolidine compounds of the general formula (I) which are inhibitors of 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase. The invention also relates to the use of these compounds in the treatment of diseases or conditions in which it is desirable to inhibit 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase including cancer, and to pharmaceutical compositions containing the compounds. |
FILED | Friday, July 16, 2010 |
APPL NO | 13/383772 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493480 | Posner et al. |
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FUNDED BY |
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APPLICANT(S) | Gary H. Posner (Baltimore, Maryland); Rachel D. Slack (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Gary H. Posner (Baltimore, Maryland); Rachel D. Slack (Baltimore, Maryland) |
ABSTRACT | Anilide derivatives of the natural trioxane artemisinin were prepared and evaluated for antimalarial efficacy in Plasmodium berghei-infected mice. Selected anilides derivatives administered orally as one single-digit dose combined with mefloquine hydrochloride were completely curative, i.e., all 5 of the mice in the particular treatment group had no detectable parasitemia on day 30 post infection, gained as much weight by day 30 post infection as the control mice (no infection), and behaved normally. |
FILED | Monday, April 16, 2012 |
APPL NO | 14/111991 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) A61K 31/537 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 493/08 (20130101) C07D 493/18 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493481 | Lindsley et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Brentwood, Tennessee); Michael R. Wood (Brentwood, Tennessee); Bruce J. Melancon (Nashville, Tennessee); James C. Tarr (Nashville, Tennessee); James M. Salovich (Nashville, Tennessee); Michael S. Poslusney (Nashville, Tennessee) |
ABSTRACT | In one aspect, the invention relates to substituted 5-aminothieno[2,3-c]pyridazine-6 -carboxamide analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
FILED | Saturday, February 23, 2013 |
APPL NO | 14/380659 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 237/26 (20130101) C07D 409/04 (20130101) C07D 495/04 (20130101) Original (OR) Class C07D 519/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1804 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493482 | Simon et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington); Fred Hutchinson Cancer Research Center (Seattle, Washington); Oricula Therapeutics LLC (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington); Oricula Therapeutics LLC (Seattle, Washington); Fred Hutchinson Cancer Research Center (Seattle, Washington) |
INVENTOR(S) | Julian Simon (Seattle, Washington); Graham Johnson (Sanbornton, New Hampshire); Edwin Rubel (Seattle, Washington); David Raible (Seattle, Washington); Mario D. Gonzalez (Winchester, Massachusetts); Peter C. Meltzer (Lexington, Massachusetts); Weishi Miao (Winchester, Massachusetts) |
ABSTRACT | Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing or treating hearing loss. The compounds and pharmaceutical compositions described herein prevent or treat hair cell death. In addition, the compounds and pharmaceutical compositions described herein protect against kidney damage in an individual receiving an aminoglycoside antibiotic. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed. |
FILED | Friday, February 05, 2016 |
APPL NO | 15/017472 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 31/7036 (20130101) Heterocyclic Compounds C07D 495/18 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493508 | Panitch et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Alyssa Panitch (West Lafayette, Indiana); Brandon Seal (Pleasant Grove, Utah); Brian C. Ward (Brownsburg, Indiana) |
ABSTRACT | The present invention provides polypeptide inhibitors of HSP27 kinase, compositions thereof, and methods for using such polypeptides and compositions for various therapeutic uses. |
FILED | Wednesday, July 03, 2013 |
APPL NO | 13/934933 |
ART UNIT | 1675 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class C07K 7/08 (20130101) C07K 14/001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493522 | Wells et al. |
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FUNDED BY |
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APPLICANT(S) | James A. Wells (Burlingame, California); Sami Mahrus (San Francisco, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | James A. Wells (Burlingame, California); Sami Mahrus (San Francisco, California) |
ABSTRACT | The present invention relates to the discovery of novel biomarkers of in vivo apoptosis based on a large number of caspase-like cleavage sites. These biomarkers are useful for detection and quantification of apoptosis in a biological sample. The invention also provides synthetic peptides and proteins corresponding to neo-epitopes created by proteolytic processing of these cleavage sites. The synthetic peptides can be used as standards to enable identification and quantitation of these biomarkers using mass spectrometry. The synthetic proteins can be used to generate antibodies and other binding reagents specific for these biomarkers. Methods for detecting apoptosis as well as for diagnosing or for providing a prognosis for a disease or disease state characterized by apoptosis are also provided herein. Finally, the invention provides compositions and kits for performing the methods of the invention. |
FILED | Friday, January 28, 2011 |
APPL NO | 13/016710 |
ART UNIT | 1678 — Organic Chemistry |
CURRENT CPC | Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/4747 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/574 (20130101) G01N 33/6848 (20130101) G01N 2333/96466 (20130101) G01N 2510/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493537 | Miao et al. |
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FUNDED BY |
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APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Louisville, Kentucky) |
ABSTRACT | The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. |
FILED | Tuesday, February 24, 2015 |
APPL NO | 14/629791 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 51/08 (20130101) A61K 51/086 (20130101) A61K 51/088 (20130101) Peptides C07K 7/54 (20130101) C07K 14/68 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493549 | Diskin et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE ROCKEFELLER UNIVERSITY (New York, New York) |
ASSIGNEE(S) | THE ROCKEFELLER UNIVERSITY (New York, New York); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Ron Diskin (Pasadena, California); Pamela J. Bjorkman (La Canada, California); Michel Nussenzweig (New York, New York); Johannes Scheid (New York, New York) |
ABSTRACT | Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) potent VRC01-like (PVL) antibodies targeted to gp120 having an amino acid substitution in the heavy chain at a residue in the anti-CD4 binding site PVL antibody that is equivalent to Phe43 in CD4 and an amino acid substitution in the light chain, these antibodies having improved potency and breadth. |
FILED | Thursday, December 13, 2012 |
APPL NO | 13/714398 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493555 | Barres et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Ben A. Barres (Palo Alto, California); Beth A. Stevens (Milton, Massachusetts) |
ABSTRACT | C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease. |
FILED | Tuesday, March 15, 2016 |
APPL NO | 15/071068 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/727 (20130101) A61K 31/727 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/5058 (20130101) G01N 33/6872 (20130101) G01N 33/6896 (20130101) G01N 2333/4716 (20130101) G01N 2500/04 (20130101) G01N 2800/28 (20130101) G01N 2800/2821 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493575 | Jaiswal et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Siddhartha Jaiswal (San Francisco, California); Irving L. Weissman (Stanford, California); Ravindra Majeti (Stanford, California); Mark P. Chao (Mountain View, California) |
ABSTRACT | Methods are provided to manipulate phagocytosis of cancer cells, including e.g. leukemias, solid tumors including carcinomas, etc. |
FILED | Tuesday, July 14, 2015 |
APPL NO | 14/799328 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 47/4863 (20130101) A61K 47/48569 (20130101) A61K 47/48607 (20130101) A61K 47/48615 (20130101) A61K 47/48623 (20130101) A61K 47/48638 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2896 (20130101) C07K 16/3038 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 16/3061 (20130101) Original (OR) Class C07K 16/3069 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493580 | Danishefsky et al. |
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FUNDED BY |
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APPLICANT(S) | Samuel J. Danishefsky (Englewood, New Jersey); Govind Ragupathi (New York, New York); Philip O. Livingston (New York, New York); Jianglong Zhu (New York, New York); David R. Spriggs (New York, New York) |
ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
INVENTOR(S) | Samuel J. Danishefsky (Englewood, New Jersey); Govind Ragupathi (New York, New York); Philip O. Livingston (New York, New York); Jianglong Zhu (New York, New York); David R. Spriggs (New York, New York) |
ABSTRACT | Glycopeptide conjugates comprising GM2 and/or Gb5 carbohydrate determinants, and methods of making and using such conjugates are disclosed. The immunogenicity of select glycopeptide conjugates is demonstrated. |
FILED | Friday, June 10, 2011 |
APPL NO | 13/703563 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/60 (20130101) A61K 2039/6081 (20130101) Peptides C07K 1/1075 (20130101) C07K 17/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493740 | Brenner et al. |
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FUNDED BY |
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APPLICANT(S) | Malcolm Brenner (Houston, Texas); Gianpietro Dotti (Houston, Texas); Nabil Ahmed (Houston, Texas); Claudia Rossig (Heidelberg, Germany); Stephen M. G. Gottschalk (Houston, Texas); Zakaria Grada (Houston, Texas) |
ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
INVENTOR(S) | Malcolm Brenner (Houston, Texas); Gianpietro Dotti (Houston, Texas); Nabil Ahmed (Houston, Texas); Claudia Rossig (Heidelberg, Germany); Stephen M. G. Gottschalk (Houston, Texas); Zakaria Grada (Houston, Texas) |
ABSTRACT | The present invention concerns immunotherapy for cancers having cells that comprise the ganglioside GD2 antigen. In specific embodiment, T cells having a chimeric receptor that targets GD2 is employed. In particular cases, the chimeric receptor comprises antibody, cytoplasmic signaling domain from the T cell receptor, and/or costimulatory molecule(s). |
FILED | Thursday, September 08, 2011 |
APPL NO | 13/820931 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493742 | Yoon et al. |
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FUNDED BY |
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APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Young Sup Yoon (Atlanta, Georgia); Gang Bao (Mableton, Georgia); Kiwon Ban (Decatur, Georgia); Brian Wile (Grayson, Georgia) |
ABSTRACT | This disclosure is in the area of research and therapeutics. In certain embodiments, it provides methods to assist in the purification of cell mixtures, e.g., cardiomyocytes, using molecular beacons targeting cell-type specific RNA, e.g. mRNA. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/211430 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 2506/02 (20130101) C12N 2506/45 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493757 | Nelsestuen |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Gary L. Nelsestuen (St. Paul, Minnesota) |
ABSTRACT | The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described. |
FILED | Wednesday, July 09, 2014 |
APPL NO | 14/326786 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/745 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/50 (20130101) Original (OR) Class C12N 9/647 (20130101) C12N 9/6437 (20130101) C12N 9/6464 (20130101) Enzymes C12Y 304/21021 (20130101) C12Y 304/21069 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493760 | Gelli |
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FUNDED BY |
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APPLICANT(S) | Angela C. Gelli (Davis, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Angela C. Gelli (Davis, California) |
ABSTRACT | The present invention relates to methods of reducing, delaying, preventing and/or inhibiting the progression of a Cryptococcus infection into the central nervous system (CNS) of a subject by inhibiting the activity of a M36 fungalysin metalloprotease (e.g., MPR1) secreted by the Cryptococcus. The invention further provides methods of increasing, promoting and/or enhancing delivery of a therapeutic agent across the blood-brain-barrier, comprising systemically administering the therapeutic agent in conjunction with a M36 fungalysin metalloprotease (e.g., MPR1), or an enzymatically active fragment thereof. |
FILED | Friday, September 07, 2012 |
APPL NO | 14/342857 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4886 (20130101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/58 (20130101) Original (OR) Class Enzymes C12Y 304/24004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493768 | Mauro et al. |
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FUNDED BY |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Vincent P. Mauro (San Diego, California); Gerald M. Edelman (La Jolla, California); Wei Zhou (San Diego, California) |
ABSTRACT | A translation enhancer-driven positive feedback vector system is disclosed which is designed to facilitate identification of a Translational Enhancer Element (TEE) and to provide a means for overexpression of gene products. The system exploits both transcriptional and translational approaches to control the expression levels of genes and/or gene products. Methods are also disclosed for screening libraries of random nucleotide sequences to identify translational elements and for overproduction of proteins, which have uses in both research and industrial environments. |
FILED | Monday, May 18, 2015 |
APPL NO | 14/715239 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) C12N 15/85 (20130101) C12N 15/1051 (20130101) Original (OR) Class C12N 15/1086 (20130101) C12N 2800/107 (20130101) C12N 2830/002 (20130101) C12N 2840/20 (20130101) C12N 2840/105 (20130101) C12N 2840/203 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493788 | Gao et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Guangping Gao (Westborough, Massachusetts); James M. Wilson (Glen Mills, Pennsylvania); Mauricio R. Alvira (Philadelphia, Pennsylvania) |
ABSTRACT | Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. |
FILED | Friday, January 16, 2015 |
APPL NO | 14/598462 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/761 (20130101) A61K 38/45 (20130101) A61K 38/177 (20130101) A61K 38/4846 (20130101) A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) C07K 14/705 (20130101) C07K 14/755 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/644 (20130101) C12N 9/1018 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14152 (20130101) C12N 2830/008 (20130101) C12N 2830/48 (20130101) C12N 2830/85 (20130101) Enzymes C12Y 201/03003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493799 | Coelho et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Pedro S. Coelho (Los Angeles, California); Eric M. Brustad (Durham, North Carolina); Frances H. Arnold (La Canada, California); Zhan Wang (San Jose, California); Jared C. Lewis (Chicago, Illinois) |
ABSTRACT | The present invention provides methods for catalyzing the conversion of an olefin to any compound containing one or more cyclopropane functional groups using heme enzymes. In certain aspects, the present invention provides a method for producing a cyclopropanation product comprising providing an olefinic substrate, a diazo reagent, and a heme enzyme; and admixing the components in a reaction for a time sufficient to produce a cyclopropanation product. In other aspects, the present invention provides heme enzymes including variants and fragments thereof that are capable of carrying out in vivo and in vitro olefin cyclopropanation reactions. Expression vectors and host cells expressing the heme enzymes are also provided by the present invention. |
FILED | Wednesday, February 18, 2015 |
APPL NO | 14/625449 |
ART UNIT | 1671 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) C12P 13/02 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493813 | Emerling et al. |
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FUNDED BY |
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APPLICANT(S) | Brooke Emerling (Boston, Massachusetts); Atsuo Sasaki (Newton, Massachusetts); Lewis C. Cantley (Cambridge, Massachusetts); Jonathan Hurov (Cambridge, Massachusetts) |
ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Brooke Emerling (Boston, Massachusetts); Atsuo Sasaki (Newton, Massachusetts); Lewis C. Cantley (Cambridge, Massachusetts); Jonathan Hurov (Cambridge, Massachusetts) |
ABSTRACT | The invention features methods for identifying compounds that modulate the activity of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K). Inhibitors of PI5P4K can be used in, for example, the treatment or prevention of cell proliferation disorders (e.g., the prevention of tumor cell growth in p53 mutated cancers). |
FILED | Friday, January 13, 2012 |
APPL NO | 13/985462 |
ART UNIT | 1674 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/02 (20130101) G01N 2500/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493818 | Kazakov et al. |
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FUNDED BY |
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APPLICANT(S) | SomaGenics, Inc. (Santa Cruz, California) |
ASSIGNEE(S) | SOMAGENICS, INC. (Santa Cruz, California) |
INVENTOR(S) | Sergei A. Kazakov (San Jose, California); Pavan Kumar (Arlington, Massachusetts); Brian H. Johnston (Scotts Valley, California) |
ABSTRACT | Currently, the circularization of small RNAs is broadly regarded as an obstacle in ligation-related assays and explicitly avoided while short lengths of linear RNA targets is broadly recognized as a factor limiting use of conventional primers in PCR-related assays. In contrast, the disclosed invention capitalizes on circularization of small RNA targets or their conjugates with oligonucleotide adapters. The circular RNA templates provide amplification of the target sequences via synthesis of multimer nucleic acids that can be either labeled for direct detection or subjected to PCR amplification and detection. Structure of small circular RNAs and corresponding multimeric nucleic acids provide certain advantages over current methods including flexibility in design of conventional RT and PCR primers as well as use of 5′-overlapping dimer-primers for efficient and sequence-specific amplification of short target sequences. Our invention also reduces number of steps and reagents while increasing sensitivity and accuracy of detection of small RNAs with both 2′OH and 2′-OMe at their 3′ ends. Our invention increase sensitivity and specificity of detection of microRNAs and other small RNAs with both 2′OH and 2′-OMe at their 3′ ends while allowing us to distinguish these two forms from each other. |
FILED | Tuesday, August 25, 2015 |
APPL NO | 14/835544 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class C12Q 1/682 (20130101) C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6865 (20130101) C12Q 1/6865 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2525/143 (20130101) C12Q 2525/207 (20130101) C12Q 2525/207 (20130101) C12Q 2525/313 (20130101) C12Q 2531/125 (20130101) C12Q 2531/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493823 | Chilkoti |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina) |
ABSTRACT | An article such as a biosensor having a nonfouling surface thereon is described. The article comprises: (a) a substrate having a surface portion; (b) a linking layer on the surface portion; (c) a polymer layer comprising brush molecules formed on the linking layer; and (d) optionally but preferably, a first member of a specific binding pair (e.g., a protein, peptide, antibody, nucleic acid, etc.) coupled to the brush molecules. The polymer layer is preferably formed by the process of surface-initiated polymerization (SIP) of monomeric units thereon. Preferably, each of the monomeric units comprises a monomer (for example, a vinyl monomer) core group having at least one protein-resistant head group coupled thereto, to thereby form the brush molecule on the surface portion. Methods of using the articles are also described. |
FILED | Thursday, January 03, 2013 |
APPL NO | 13/733302 |
ART UNIT | 1677 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/0061 (20130101) B01J 2219/0063 (20130101) B01J 2219/0074 (20130101) B01J 2219/00432 (20130101) B01J 2219/00596 (20130101) B01J 2219/00605 (20130101) B01J 2219/00608 (20130101) B01J 2219/00612 (20130101) B01J 2219/00626 (20130101) B01J 2219/00628 (20130101) B01J 2219/00635 (20130101) B01J 2219/00637 (20130101) B01J 2219/00659 (20130101) B01J 2219/00677 (20130101) B01J 2219/00722 (20130101) B01J 2219/00725 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 2521/131 (20130101) C12Q 2525/313 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5302 (20130101) G01N 33/54393 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493826 | Ismagilov et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California); University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); UNIVERSITY OF CHICAGO (Chicago, Illinois) |
INVENTOR(S) | Rustem F. Ismagilov (Altadena, California); Feng Shen (Pasadena, California); Jason E. Kreutz (Marysville, Washington); Wenbin Du (Wenzhou, China PRC); Bing Sun (Pasadena, California) |
ABSTRACT | Provided are devices comprising multivolume analysis regions, the devices being capable of supporting amplification, detection, and other processes. Also provided are related methods of detecting or estimating the presence nucleic acids, viral levels, and other biological markers of interest. |
FILED | Monday, February 10, 2014 |
APPL NO | 14/177190 |
ART UNIT | 1799 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0094 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/50851 (20130101) B01L 3/502738 (20130101) B01L 2200/027 (20130101) B01L 2200/0605 (20130101) B01L 2200/0642 (20130101) B01L 2300/045 (20130101) B01L 2300/049 (20130101) B01L 2300/0803 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2400/065 (20130101) B01L 2400/0406 (20130101) B01L 2400/0644 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 2531/119 (20130101) C12Q 2537/149 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493837 | Gbadegesin et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Rasheed A. Gbadegesin (Durham, North Carolina); Michelle P. Winn (Durham, North Carolina) |
ABSTRACT | Isolated nucleotides encoding polypeptides with mutations leading to amino acid substitutions linked to hereditary kidney disease or malformation of the urinary tract are provided herein. Constructs, cells, probes and inhibitory molecules comprising these mutations are also provided and may be used in screening assays for candidate agents to treat or reverse these diseases or alternatively to provide diagnostic tests. Methods of diagnosing subjects likely to develop these diseases or to be carriers of these diseases are also provided. |
FILED | Wednesday, October 02, 2013 |
APPL NO | 14/044602 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493842 | Giaccone et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Giuseppe Giaccone (Bethesda, Maryland); Yisong Wang (Columbia, Maryland); Iacopo Petrini (Pisa, Italy) |
ABSTRACT | Disclosed are methods of determining the prognosis of thymic cancer in a subject comprising detecting a mutation in the general transcription factor IIi (GTF2I) genetic sequence or protein. The presence of a GTF2I mutation indicates that the thymic cancer is indolent. |
FILED | Thursday, April 02, 2015 |
APPL NO | 14/676987 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 2333/4703 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493846 | Ding et al. |
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FUNDED BY |
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APPLICANT(S) | Shou-Wei Ding (Riverside, California); Qingfa Wu (Riverside, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Shou-Wei Ding (Riverside, California); Qingfa Wu (Riverside, California) |
ABSTRACT | In one embodiment, the disclosure provides methods and systems for identifying viral nucleic acids in a sample. In another embodiment the invention provides methods for viral genome assembly and viral discovery using small inhibitory RNAs, or “small silencing,” RNAs (siRNAS), micro-RNAs (miRNAs) and/or PIWI-interacting RNAs (piRNAs), including siRNAS, miRNAs and/or piRNAs isolated or sequenced from invertebrate organisms such as insects (Anthropoda), nematodes (Nemapoda), Mollusca, Porifera, and other invertebrates, and/or plants, fungi or algae, Cyanobacteria and the like. |
FILED | Tuesday, June 01, 2010 |
APPL NO | 13/375467 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Original (OR) Class C12Q 2600/178 (20130101) Electric Digital Data Processing G06F 19/14 (20130101) G06F 19/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493847 | Huang |
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FUNDED BY |
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APPLICANT(S) | Wei Huang (Foster City, California) |
ASSIGNEE(S) | MONOGRAM BIOSCIENCES, INC. (San Francisco, California) |
INVENTOR(S) | Wei Huang (Foster City, California) |
ABSTRACT | The invention provides a method for determining whether a human immunodeficiency virus is likely to be have enhanced ability to enter a cell expressing CD4 and CXCR4 relative to a reference HIV. In certain aspects, the methods comprise detecting one or more amino acids in an envelope protein of the HIV associated with enhanced ability to enter CD4- and CXCR4-expressing cells and determining that the HIV's ability to enter such cells is enhanced relative to a reference HIV, e.g., an HIV that does not comprise such amino acid(s). |
FILED | Thursday, February 09, 2012 |
APPL NO | 13/370109 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494498 | Pamula et al. |
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FUNDED BY |
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APPLICANT(S) | Advanced Liquid Logic, Inc. (San Diego, California) |
ASSIGNEE(S) | Advanced Liquid Logic, Inc. (San Diego, California) |
INVENTOR(S) | Vamsee K. Pamula (Cary, North Carolina); Ramakrishna Sista (Cary, North Carolina); Vijay Srinivasan (Cary, North Carolina); Michael G. Pollack (Durham, North Carolina); Allen Eckhardt (San Diego, California) |
ABSTRACT | The invention provides a method of circulating magnetically responsive beads within a droplet in a droplet actuator. The invention also provides methods for splitting droplets. The invention, in one embodiment, makes use of a droplet actuator with top and bottom substrates, a plurality of magnetic fields respectively present proximate the top and bottom substrates, wherein at least one of the magnet fields is selectively alterable, and a plurality of droplet operations electrodes positioned along at least one of the top and bottom surfaces. A droplet is positioned between the top and bottom surfaces and at least one of the magnetic fields is selectively altered. |
FILED | Tuesday, December 22, 2015 |
APPL NO | 14/978935 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 11/0071 (20130101) B01F 13/0071 (20130101) B01F 13/0076 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502792 (20130101) B01L 7/52 (20130101) B01L 7/525 (20130101) B01L 2200/027 (20130101) B01L 2200/0647 (20130101) B01L 2300/089 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/1827 (20130101) B01L 2400/043 (20130101) B01L 2400/0406 (20130101) B01L 2400/0415 (20130101) B01L 2400/0421 (20130101) B01L 2400/0424 (20130101) B01L 2400/0427 (20130101) B01L 2400/0436 (20130101) B01L 2400/0442 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) Original (OR) Class G01N 33/54326 (20130101) G01N 2001/386 (20130101) G01N 2035/1046 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/11 (20150115) Y10T 436/25 (20150115) Y10T 436/2575 (20150115) Y10T 436/25625 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494592 | Xian et al. |
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FUNDED BY |
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APPLICANT(S) | Washington State University (Pullman, Washington) |
ASSIGNEE(S) | Washington State University (Pullman, Washington) |
INVENTOR(S) | Ming Xian (Pullman, Washington); Wei Chen (Pullman, Washington) |
ABSTRACT | Reaction-based fluorescent probes are provided which detect, for example, biologically important sulfane sulfur species (persulfide, polysulfide, and elemental sulfur) in, for example, complex and living systems. The probes are high in selectivity and sensitivity to sulfane sulfurs. Moreover, probes are suitable for bioimaging sulfane sulfurs in living cells. |
FILED | Friday, April 11, 2014 |
APPL NO | 14/250481 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0041 (20130101) A61K 49/0043 (20130101) Heterocyclic Compounds C07D 311/16 (20130101) C07D 493/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/182 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494668 | Bottomley et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Paul A. Bottomley (Baltimore, Maryland); Guan Wang (Baltimore, Maryland); Abdel-Monem M. El-Sharkawy (Baltimore, Maryland) |
ABSTRACT | A system for measuring nuclear magnetic resonance spin-lattice relaxation time T1 and spin-spin relaxation time T2 of a sample includes a source of a substantially uniform magnetic field B0 for immersing at least a portion of the sample; a nuclear magnetic resonance excitation and detection system constructed and arranged to excite at least a portion of the sample with a plurality of nuclear magnetic resonance pulse sequences, each applied with a repetition time that is preselected to be sensitive to a T1 value of at least a portion of the sample, and to detect nuclear magnetic resonance emissions from the sample in response to excitations to provide a plurality of detection signals; and a signal processing system configured to communicate with the nuclear magnetic resonance excitation and detection system to receive the plurality of detection signals. |
FILED | Monday, December 03, 2012 |
APPL NO | 13/692726 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) Original (OR) Class G01R 33/54 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494669 | Song et al. |
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FUNDED BY |
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APPLICANT(S) | Sheng-Kwei Song (Manchester, Missouri); Qing Wang (St. Louis, Missouri); Yong Wang (St. Louis, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Sheng-Kwei Song (Manchester, Missouri); Qing Wang (St. Louis, Missouri); Yong Wang (St. Louis, Missouri) |
ABSTRACT | Determining diffusivity of multiple diffusion components within a tissue using diffusion magnetic resonance data representing a volume of the tissue. A plurality of candidate fibers having a direction is defined within the volume. A possibility coefficient is calculated by a processor for each candidate fiber of the plurality of candidate fibers based on the magnetic resonance data and the direction of the candidate fiber. The possibility coefficient represents a likelihood that the candidate fiber exists in the volume. Candidate fibers associated with a possibility coefficient greater than a threshold value are selected by the processor to create one or more probable fibers. For each probable fiber of the one or more probable fibers, an axial diffusivity indicating a diffusion of water in the direction of the probable fiber and a radial diffusivity indicating a diffusion of water perpendicular to the direction of the probable fiber are calculated by the processor. The diffusivity of isotropic diffusion component and the volume ratios of each fiber component and isotropic components are calculated. |
FILED | Tuesday, May 17, 2011 |
APPL NO | 13/109986 |
ART UNIT | 3777 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/56341 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495378 | Sundaram et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Vinaitheerthan Sundaram (West Lafayette, Indiana); Patrick Eugster (West Lafayette, Indiana); Xiangyu Zhang (West Lafayette, Indiana) |
ABSTRACT | A packet of data and a packet-identification value are transmitted to a network device having an identifier. The stored packet-identification value and the identifier are recorded. The stored packet-identification value is then increased and the process repeats. To receive data, an expected identification value is stored in association with the identifier. A packet and a packet-identification value are received from the network device. The identifier and an indication of receipt are stored. If the received value does not match the expected value for the identifier, the received value is stored. If the values match, the stored packet-identification value and identifier are recorded. If the received value exceeds the expected value, the stored packet-identification value, the identifier and the received identifier are recorded. Subsequently, the stored expected value is increased. The process repeats. Network devices and systems are described. |
FILED | Wednesday, August 27, 2014 |
APPL NO | 14/470112 |
ART UNIT | 2471 — Multiplex and VoIP |
CURRENT CPC | Electric Digital Data Processing G06F 11/3636 (20130101) G06F 17/30153 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 43/062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495517 | Ahearn et al. |
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FUNDED BY |
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APPLICANT(S) | Allegheny-Singer Research Institute (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | Allegheny-Singer Research Institute (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Joseph M. Ahearn (Wexford, Pennsylvania); Chau-Ching Liu (Pittsburgh, Pennsylvania); Susan M. Manzi (Wexford, Pennsylvania) |
ABSTRACT | Cell-bound complement activation product (CB-CAP) profiling and scoring serve as diagnostic biomarkers for patients to determine whether a patient who has not met at least four American College of Rheumatology (or similar e.g. SLICC) criteria for a definite Lupus diagnosis should be classified as exhibiting a pre-existing condition that this document refers to as pre-Lupus. |
FILED | Thursday, August 06, 2015 |
APPL NO | 14/820029 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/49 (20130101) G01N 33/564 (20130101) G01N 2800/24 (20130101) Electric Digital Data Processing G06F 19/345 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495746 | Chou et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
INVENTOR(S) | Chen-Rui Chou (Raleigh, North Carolina); Stephen Pizer (Chapel Hill, North Carolina) |
ABSTRACT | Methods, systems, and computer readable media for real-time 2D/3D deformable registration using metric learning are disclosed. According to one aspect, a method for real-time 2D/3D deformable registration using metric learning includes creating a catalog of simulated 2D projection images based on a reference 3D image and a shape space of 3D deformations, where each entry in the catalog is created by: applying to the reference 3D image a set of deformation parameters from the shape space of deformations; simulating a 2D projection of the result; associating the simulated 2D projection image with the deformation parameters used to create the simulated 2D projection image; and storing the simulated 2D projection image and associated deformation parameters in the catalog. The method also includes receiving a 2D image, and, in response to receiving the 2D image: calculating a value of distance between the received 2D image and a simulated 2D projection image for each of the simulated 2D projection images in the catalog; using the calculated distances to calculate weighting factors to be applied to the deformation parameters of each of the simulated 2D projection images in the catalog; and calculating deformation parameters for the received 2D image based on the weighted deformation parameters in the catalog. The calculated deformation parameters are then used to deform a 3D volume of interest to produce a 3D volume that represents the 3D layout of the tissue at the time that the received 2D image was acquired. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/776873 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0028 (20130101) G06T 7/0032 (20130101) G06T 7/0034 (20130101) Original (OR) Class G06T 11/003 (20130101) G06T 15/08 (20130101) G06T 2200/04 (20130101) G06T 2207/10081 (20130101) G06T 2207/20016 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20116 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) G06T 2211/428 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495771 | El Fakhri et al. |
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FUNDED BY |
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APPLICANT(S) | Georges El Fakhri (Brookline, Massachusetts); Chuan Huang (Boston, Massachusetts); Jinsong Ouyang (Lexington, Massachusetts); Quanzheng Li (Cambridge, Massachusetts); Yoann Petibon (Cambridge, Massachusetts); Joyita Dutta (Brookline, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Georges El Fakhri (Brookline, Massachusetts); Chuan Huang (Boston, Massachusetts); Jinsong Ouyang (Lexington, Massachusetts); Quanzheng Li (Cambridge, Massachusetts); Yoann Petibon (Cambridge, Massachusetts); Joyita Dutta (Brookline, Massachusetts) |
ABSTRACT | Systems and methods for compensating motion artifacts in positron emission tomography (“PET”) imaging based on medical images acquired with a medical imaging system are provided. In some embodiments, the method includes acquiring PET data from a subject with a PET system during which at least a portion of the subject is undergoing motion, and providing medical images acquired from the subject using a medical imaging system, the medical images including regions depicting motion. The method also includes estimating, from the medical images, motion information associated with the motion of the at least a portion of the subject, and reconstructing a motion-corrected PET image using the PET data using a reconstruction algorithm that incorporates the motion information into a system matrix. |
FILED | Friday, May 09, 2014 |
APPL NO | 14/274340 |
ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/5264 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) Original (OR) Class G06T 11/006 (20130101) G06T 2211/412 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497379 | Ou et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Xiaoze Ou (Pasadena, California); Roarke Horstmeyer (San Marino, California); Guoan Zheng (Vernon, Connecticut); Changhuei Yang (Alhambra, California) |
ABSTRACT | Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier ptychographic imaging systems. |
FILED | Friday, August 22, 2014 |
APPL NO | 14/466481 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Pictorial Communication, e.g Television H04N 5/32 (20130101) H04N 5/2256 (20130101) H04N 5/23232 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 09491990 | Sadeck |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Wahshington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | James E. Sadeck (East Freetown, Massachusetts) |
ABSTRACT | Apparatuses and system are provided for securing loads. In one embodiment, a buckle system is provided that includes two buckle portions that are adapted to interlock with each other. Each of the buckle portions includes a spine, two longitudinal/long member connected to the spine, a neck connected to the spine and a V-shaped member, and two horizontal members connected to the V-shaped member. Each of the two buckle portions has a plurality of bends on its top surface. The plurality of bends one buckle portion corresponds with the plurality of bends on the other buckle portion. In various embodiments, each spine has at least one portion that has greater dimensions than at least one other portion on the spine, respectively. |
FILED | Wednesday, June 04, 2014 |
APPL NO | 14/295366 |
ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Buttons, Pins, Buckles, Slide Fasteners, or the Like A44B 11/00 (20130101) Original (OR) Class A44B 11/02 (20130101) A44B 11/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492428 | Hammond et al. |
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FUNDED BY |
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APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky); Cayetano Heredia University (S.M.P. Lima, Peru) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Gerald B. Hammond (Shelbyville, Kentucky); Zhuang Jin (West Palm Beach, Florida); Paula J. Bates (Louisville, Kentucky); Elsa Merit Reyes-Reyes (Prospect, Kentucky); Abraham Vaisberg (Lima, Peru) |
ABSTRACT | Certain embodiments of the invention include compositions comprising a compound of Formula (I), and salts, isomers, and derivatives thereof. Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I), and salts, isomers, and derivatives thereof. Other embodiments of this invention include methods for treating disease (e.g., cancer) and methods for administering a compound of Formula (I), and salts, isomers, and derivatives thereof. |
FILED | Friday, November 16, 2012 |
APPL NO | 14/358731 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/366 (20130101) Original (OR) Class A61K 36/81 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492504 | Leisk et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | Gary G. Leisk (Wilmington, Massachusetts); Tim Jia-Ching Lo (Medford, Massachusetts); Lei Li (Beijing, China PRC); Evangelia Bellas (Somerville, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
ABSTRACT | The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection). In some embodiments, the composition described herein comprises a compressed silk fibroin matrix, which can expand upon injection into the tissue and retain its original expanded volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation. |
FILED | Friday, November 09, 2012 |
APPL NO | 14/357420 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1767 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) A61L 27/3604 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/34 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492870 | Kaplowitz et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel Kaplowitz (Harrington Park, New Jersey); R. Jason Jouet (Indian Head, Maryland); Michael R. Zachariah (Potomac, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Daniel Kaplowitz (Harrington Park, New Jersey); R. Jason Jouet (Indian Head, Maryland); Michael R. Zachariah (Potomac, Maryland) |
ABSTRACT | Low temperature gas-phase methods for the preparation of faceted aluminum crystals are disclosed. |
FILED | Friday, September 14, 2012 |
APPL NO | 13/619017 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0018 (20130101) B22F 1/0085 (20130101) B22F 1/0088 (20130101) B22F 1/0088 (20130101) B22F 9/24 (20130101) Original (OR) Class B22F 9/30 (20130101) B22F 2001/0037 (20130101) B22F 2201/03 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Alloys C22C 21/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492930 | Galloway |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Kevin Galloway (Somerville, Massachusetts) |
ABSTRACT | A mechanically programmed actuator includes at least one soft actuator body configured to bend, linearly extend, contract, twist, or combinations thereof when actuated without constraint; an activation mechanism (e.g., a fluid pump) configured to actuate the soft actuator body; and at least one sleeve wrapped around part of the soft actuator body and configured to constrain the soft actuator body inside the sleeve when actuated and to cause the soft actuator body to deform where not covered by the sleeve. |
FILED | Thursday, October 16, 2014 |
APPL NO | 15/028993 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) B25J 15/12 (20130101) B25J 15/0023 (20130101) B25J 18/06 (20130101) Original (OR) Class Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493025 | Farmer et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Damon B. Farmer (White Plains, New York); Dirk Pfeiffer (Croton on Hudson, New York); Joshua T. Smith (Croton on Hudson, New York) |
ABSTRACT | Aspects of the present disclosure relate to a security device, in particular, a multilayered security device. The multilayered security device includes a substrate layer having a first substrate. The substrate layer attaches to the product. The multilayered security device also includes a graphene layer. The graphene layer has a first continuous graphene sheet that is made of a monolayer of covalently-bonded carbon atoms. The graphene layer also forms, in response to exposure to a verification stimulus, a contrasting pattern with respect to an exposed substrate area from the substrate layer. |
FILED | Monday, January 19, 2015 |
APPL NO | 14/599637 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/36 (20141001) Original (OR) Class B42D 25/465 (20141001) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/95607 (20130101) G01N 2201/062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493230 | Balsiger |
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FUNDED BY |
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APPLICANT(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
ASSIGNEE(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
INVENTOR(S) | Derick Balsiger (Mayer, Arizona) |
ABSTRACT | A drive assembly with selective disconnect includes a motor with a motor drive shaft; a harmonic drive coupled to one end of the motor drive shaft; an output shaft coupled to the harmonic drive; and a retracting mechanism that selectively retracts the motor drive shaft axially to decouple the motor drive shaft from the harmonic drive. |
FILED | Thursday, November 21, 2013 |
APPL NO | 14/086001 |
ART UNIT | 3658 — Material and Article Handling |
CURRENT CPC | Aeroplanes; Helicopters B64C 13/34 (20130101) Original (OR) Class B64C 13/42 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 27/108 (20130101) Gearing F16H 3/22 (20130101) F16H 37/04 (20130101) F16H 49/001 (20130101) F16H 55/0833 (20130101) F16H 63/34 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/44 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/19614 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493252 | Tsay et al. |
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FUNDED BY |
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APPLICANT(S) | Busek Co., Inc. (Natick, Massachusetts) |
ASSIGNEE(S) | Busek Co., Inc. (Natick, Massachusetts) |
INVENTOR(S) | Michael M. Tsay (North Chelmsford, Massachusetts); Vladimir J. Hruby (Waban, Massachusetts); Christopher M. Grenier (Dudley, Massachusetts); William P. Costa (Norfolk, Massachusetts); Derek J. Lafko (Holliston, Massachusetts) |
ABSTRACT | A thruster includes a reactor including bundled metal elongate members therein configured to disassociate an introduced propellant flowing between the members, a combustor for combusting products of the disassociation, and a nozzle downstream of the combustor. |
FILED | Wednesday, April 23, 2014 |
APPL NO | 14/259468 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/401 (20130101) Original (OR) Class Jet-propulsion Plants F02K 9/68 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493356 | Hunt et al. |
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FUNDED BY |
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APPLICANT(S) | Joseph R. Hunt (King George, Virginia); Timothy P. Burgin (Scottsdale, Arizona) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Joseph R. Hunt (King George, Virginia); Timothy P. Burgin (Scottsdale, Arizona) |
ABSTRACT | A filtration material is provided for incorporation in a gas filter that includes an Activated Carbon, Impregnated with Copper, Silver, Zinc, Molybdenum, and Triethlyenediamine (ASZM-TEDA) medium and a macrocyclic organic material. The material is impregnated into the medium in proportions of between 1% and 5% of the medium. The material consists of molecules, each with a binding pocket for binding a metal ion. Also, a method is provided for impregnating porphyrin into a medium of ASZM-TEDA for incorporation in a gas filter. The method includes mixing porphyrin and ASZM-TEDA in a first ratio-by-weight of 1:4 of porphyrin to ASZM-TEDA as a mixture in a container; adding dichloromethane to the mixture in a second ratio-by-weight of 1:133 of porphyrin to dichloromethane as a solution in the container; stirring and refluxing the solution under nitrogen, filtering said mixture from the solution as a carbon residue; and drying the residue. |
FILED | Friday, July 17, 2015 |
APPL NO | 14/802988 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493537 | Miao et al. |
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FUNDED BY |
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APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Louisville, Kentucky) |
ABSTRACT | The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. |
FILED | Tuesday, February 24, 2015 |
APPL NO | 14/629791 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 51/08 (20130101) A61K 51/086 (20130101) A61K 51/088 (20130101) Peptides C07K 7/54 (20130101) C07K 14/68 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493547 | Baker et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
ASSIGNEE(S) | University of Washington Through its Center for Commercialization (Seattle, Washington) |
INVENTOR(S) | David Baker (Seattle, Washington); Eva-Maria Strauch (Seattle, Washington); Sarel Jacob Fleishman (Rehovot, Israel) |
ABSTRACT | The present invention provides polypeptides that bind to immunoglobulin G and methods for their use. |
FILED | Monday, March 25, 2013 |
APPL NO | 14/387699 |
ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) Peptides C07K 1/22 (20130101) C07K 14/001 (20130101) C07K 16/00 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/80 (20130101) Enzymes C12Y 305/01019 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493717 | Harvey |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California) |
ABSTRACT | A method to generate cyclic hydrocarbons from farnesene to increase both the density and net heat of combustion of the product fuels. The high density hydrocarbons produced by this method have applications for missile, UAV, jet, and diesel propulsion. |
FILED | Wednesday, June 25, 2014 |
APPL NO | 14/314305 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/10 (20130101) B01J 31/2273 (20130101) B01J 31/2278 (20130101) B01J 2231/543 (20130101) B01J 2231/645 (20130101) B01J 2531/821 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 45/00 (20130101) C10G 50/00 (20130101) C10G 65/043 (20130101) C10G 69/126 (20130101) C10G 2300/44 (20130101) C10G 2300/302 (20130101) C10G 2300/308 (20130101) C10G 2300/703 (20130101) C10G 2300/1011 (20130101) C10G 2300/1092 (20130101) C10G 2400/04 (20130101) C10G 2400/22 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) Original (OR) Class C10L 1/08 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493765 | Krishnaswamy et al. |
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FUNDED BY |
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APPLICANT(S) | Pavitra Krishnaswamy (Cambridge, Massachusetts); Andras Kuthi (Thousand Oaks, California) |
ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Pavitra Krishnaswamy (Cambridge, Massachusetts); Andras Kuthi (Thousand Oaks, California) |
ABSTRACT | Disclosed are methods and systems for subnanosecond rise time high voltage (HV) electric pulse delivery to biological loads. The system includes an imaging device and monitoring apparatus used for bio-photonic studies of pulse induced intracellular effects. The system further features a custom fabricated microscope slide having micro-machined electrodes. A printed circuit board to interface the pulse generator to the micro-machined glass slide having the cell solution is disclosed. An low-parasitic electronic setup to interface with avalanche transistor-switched pulse generation system is also disclosed. The pc-board and the slide are configured to match the output impedance of the pulse generator which minimizes reflection back into the pulse generator, and minimizes distortion of the pulse shape and pulse parameters. The pc-board further includes a high bandwidth voltage divider for real-time monitoring of pulses delivered to the cell solutions. |
FILED | Monday, March 24, 2008 |
APPL NO | 12/079017 |
ART UNIT | 1799 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) A61N 1/0408 (20130101) A61N 1/0412 (20130101) A61N 1/0452 (20130101) A61N 1/0456 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Original (OR) Class Pulse Technique H03K 3/57 (20130101) H03K 3/537 (20130101) H03K 5/159 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493805 | Reardon et al. |
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FUNDED BY |
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APPLICANT(S) | Kenneth F. Reardon (Fort Collins, Colorado); David S. Dandy (Fort Collins, Colorado); Michael Fritzsche (Burgdorf, Germany); Thomas K. Wood (College Station, Texas) |
ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
INVENTOR(S) | Kenneth F. Reardon (Fort Collins, Colorado); David S. Dandy (Fort Collins, Colorado); Michael Fritzsche (Burgdorf, Germany); Thomas K. Wood (College Station, Texas) |
ABSTRACT | Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor. |
FILED | Wednesday, April 09, 2008 |
APPL NO | 12/100308 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/002 (20130101) Original (OR) Class C12Q 1/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/914 (20130101) G01N 2333/988 (20130101) G01N 2333/90241 (20130101) G01N 2333/90245 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493806 | Reardon |
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FUNDED BY |
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APPLICANT(S) | Kenneth F. Reardon (Fort Collins, Colorado) |
ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
INVENTOR(S) | Kenneth F. Reardon (Fort Collins, Colorado) |
ABSTRACT | Biosensors and methods of producing biosensors for use in detecting one or more analytes in a solution are disclosed herein. |
FILED | Tuesday, July 31, 2012 |
APPL NO | 13/562592 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/002 (20130101) C12Q 1/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/914 (20130101) G01N 2333/988 (20130101) G01N 2333/90241 (20130101) G01N 2333/90245 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493825 | Mohapatra et al. |
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FUNDED BY |
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APPLICANT(S) | Shyam S. Mohapatra (Lutz, Florida); Jia-Wang Wang (Tampa, Florida) |
ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
INVENTOR(S) | Shyam S. Mohapatra (Lutz, Florida); Jia-Wang Wang (Tampa, Florida) |
ABSTRACT | The present invention provides materials and methods for detecting, quantifying, and/or high-throughput-profiling microRNAs. Advantageously, the present invention is more sensitive and specific than other currently-available miRNA qPCR assays. In addition, the present invention is convenient, easy-to-perform, and cost-effective. In one embodiment, the present invention provides a universal primer for reverse transcription of all miRNAs, a universal reverse primer for PCR amplification reaction, and universal probes. In another embodiment, the present invention provides assays that allow simultaneous detection and/or quantification of a plurality of target miRNAs using a single reverse transcription reaction. |
FILED | Friday, March 16, 2012 |
APPL NO | 14/000517 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 1/6876 (20130101) C12Q 2525/161 (20130101) C12Q 2525/173 (20130101) C12Q 2525/207 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493833 | Deshaies et al. |
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FUNDED BY |
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APPLICANT(S) | Raymond J. Deshaies (Claremont, California); Senthil Radhakrishnan (Pasadena, California); Candy S. Lee (Diamond Bar, California); Jefferson Y. Chan (Irvine, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Raymond J. Deshaies (Claremont, California); Senthil Radhakrishnan (Pasadena, California); Candy S. Lee (Diamond Bar, California); Jefferson Y. Chan (Irvine, California) |
ABSTRACT | Methods and compositions for inhibiting Nrf1 activity are provided for enhancing apoptosis in mammalian cells. Apoptosis is enhanced in mammalian cells by co-inhibiting Nrf1 activity and proteasome activity. Methods for identifying Nrf1 inhibitors are provided using an assay for screening Nrf1 inhibitors that enhance proteasome inhibition by preventing induced proteasome expression. |
FILED | Monday, November 08, 2010 |
APPL NO | 12/941959 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493841 | Tavazoie et al. |
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FUNDED BY |
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APPLICANT(S) | Sohail Tavazoie (New York, New York); Nils Halberg (Brooklyn, New York); Kim Png (Singapore, Singapore) |
ASSIGNEE(S) | The Rockefeller University (New York, New York) |
INVENTOR(S) | Sohail Tavazoie (New York, New York); Nils Halberg (Brooklyn, New York); Kim Png (Singapore, Singapore) |
ABSTRACT | This invention concerns pathological angiogenesis and cancer, related treatment methods, and related compositions. Also disclosed are related diagnosis kits and methods. |
FILED | Monday, March 16, 2015 |
APPL NO | 14/658927 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 39/3955 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/18 (20130101) C07K 2316/96 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 2310/141 (20130101) C12N 2320/11 (20130101) C12N 2330/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/136 (20130101) C12Q 2600/178 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493887 | Kolis et al. |
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FUNDED BY |
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APPLICANT(S) | Clemson University (Clemson, South Carolina) |
ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
INVENTOR(S) | Joseph W. Kolis (Central, South Carolina); Colin D. McMillen (Liberty, South Carolina); J. Matthew Mann (Anderson, South Carolina) |
ABSTRACT | Disclosed are heterogeneous crystals for use in a laser cavity and methods of forming the crystals. A crystal can be a monolithic crystal containing a vanadate-based activator region and a vanadate-based Q-switch. Disclosed methods include hydrothermal growth techniques for the growth of differing layers on a host. A YVO4 host material can be doped in one region with a suitable active lasing ion and can be formed with another region that is doped with a saturable absorber. Regions can be formed with controlled thickness. Following formation, a heterogeneous crystal can be cut, polished and coated with mirror films at each end for use in a laser cavity to provide short pulses of high power emissions using high frequency pulse modes. |
FILED | Friday, September 26, 2014 |
APPL NO | 14/497949 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/00 (20130101) C30B 7/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494246 | Potter et al. |
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FUNDED BY |
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APPLICANT(S) | Google Inc. (Mountain View, California) |
ASSIGNEE(S) | Google Inc. (Mountain View, California) |
INVENTOR(S) | Steve Potter (Bedford, Massachusetts); Haink Tu (Waltham, Massachusetts) |
ABSTRACT | Examples are provided that describe a linear hydraulic valve. In one example a linear valve comprises a sleeve with a plurality of ports spaced apart from each other at a distance. The plurality of ports are associated with a plurality of pressurized fluids. A spool comprising a plurality of openings that correspond to the plurality of ports is provided within the sleeve. The plurality of openings are spaced apart in a manner that enables alignment of a given opening of the plurality of openings to a given port of the plurality of ports based on a given position of the spool within the sleeve. The linear valve comprises an actuator for moving the spool in a forward or reverse linear motion along a longitudinal axis of the sleeve. The spool may be moved to a given position based on selection of a pressurized fluid of the plurality of pressurized fluids. |
FILED | Wednesday, December 31, 2014 |
APPL NO | 14/587873 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/0716 (20130101) F16K 31/04 (20130101) Original (OR) Class F16K 31/0613 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/86879 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494395 | Smallin |
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FUNDED BY |
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APPLICANT(S) | Bryan J. Smallin (Panama City, Florida) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Bryan J. Smallin (Panama City, Florida) |
ABSTRACT | A mine emulation system includes a standard electronics section. The system can be reconfigured into several different mine shapes by the use of different end sections attached to the electronics section. The electronics sections can include an array of sensors, including magnetic, seismic, pressure and passive acoustic sensors. The electronics can be programmable such that the sensors can emulate the various mine types as well as differing mines within each type. An active acoustic communication system allows surface ships or RF buoy systems to communicate with the mine emulator. An operator can provide a release command to an acoustically operated release system via the acoustic communication system. |
FILED | Monday, August 26, 2013 |
APPL NO | 13/975791 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 8/28 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494425 | Najafi et al. |
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FUNDED BY |
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APPLICANT(S) | Khalil Najafi (Ann Arbor, Michigan); Jae Yoong Cho (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Khalil Najafi (Ann Arbor, Michigan); Jae Yoong Cho (Ann Arbor, Michigan) |
ABSTRACT | A gyroscope having a mechanical resonator, a plurality of electrodes located around the resonator, and a thin gap being located between the resonator and the plurality of electrodes. The resonator is axi-symmetric and may be at least partially toroidal in shape or composed of concentric rings. Piezoelectric electrodes or transduction may be used to drive or detect displacements of the resonator. The resonator may be fabricated using a fused silica flowing process. |
FILED | Friday, May 25, 2012 |
APPL NO | 13/481650 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/28 (20130101) Original (OR) Class G01C 19/5691 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/1275 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494451 | Cole |
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FUNDED BY |
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APPLICANT(S) | Robert E. Cole (Panama City, Florida) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Robert E. Cole (Panama City, Florida) |
ABSTRACT | A support and alignment apparatus for a traversing pitot tube is provided. The apparatus includes a support strut, an insertion fitting and a termination fitting. The support strut spans within the duct, with each end of the strut being attached to one of the fittings. The pitot tube is routed through the insertion fitting and into the support strut. The strut supports the pitot tube as it traverses the duct. A slot cut along the length of the strut allows the pitot tube to extend away from the strut, into and parallel to the flow. The slot aligns the end of the pitot tube with the flow and prevents unwanted rotation, vibration, and flexing of the pitot tube to increase measurement accuracy. |
FILED | Thursday, March 26, 2015 |
APPL NO | 14/670011 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/46 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494492 | Brunschwig et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Anya R. Brunschwig (Wethersfield, Connecticut); Amy R. Nordmark (Ellington, Connecticut); Bryan P. Donovan (Pacific Palisades, California); Andrew D. Ruestow (Hartford, Connecticut); Gregory J. Kacprzynski (Fairport, New York); Charles Pelosi (Jupiter, Florida) |
ABSTRACT | An automated method for resolving fault in an engine is disclosed. The method may include providing a reasoner module for recommending a set of maintenance actions to resolve fault in the engine, inputting steady state performance data from the engine into the reasoner module, and using the reasoner module to recommend a set of maintenance actions based at least in part on the steady state performance data. A fault resolution system for a gas turbine engine is also disclosed. The fault resolution system may include at least one computer processor operatively configured to receive steady state performance data from the gas turbine engine, and recommend a set of maintenance actions to resolve fault in the gas turbine engine based at least in part on the steady state performance data. |
FILED | Thursday, December 19, 2013 |
APPL NO | 14/134398 |
ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494579 | Schwoebel et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Eric D. Schwoebel (Woburn, Massachusetts); James D. Harper (Jamaica Plain, Massachusetts); Martha S. Petrovick (Barre, Massachusetts); Frances E. Nargi (Littleton, Massachusetts); Todd H. Rider (Littleton, Massachusetts); Kristine E. Hogan (Danvers, Massachusetts); Richard H. Mathews (Chelmsford, Massachusetts); Joseph Lacirignola (Beverly, Massachusetts); Mark Hennessy (Morrisville, North Carolina); Trina R. Vian (Groton, Massachusetts); Rose M. Joseph (Westford, Massachusetts); Raymond S. Uttaro (Lexington, Massachusetts); Shaun Berry (Chelmsford, Massachusetts); Bernadette Johnson (Hollis, New Hampshire); Mark A. Hollis (Concord, Massachusetts) |
ABSTRACT | The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples. |
FILED | Tuesday, September 09, 2014 |
APPL NO | 14/481044 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 1/3461 (20130101) C12M 1/3476 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 2563/131 (20130101) C12Q 2565/619 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6454 (20130101) G01N 33/582 (20130101) G01N 33/5304 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494715 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Ho Wai Lee (Pasadena, California); Stanley Burgos (San Jose, California); Georgia Papadakis (Pasadena, California); Harry A. Atwater (South Pasadena, California) |
ABSTRACT | A plasmonic device having a transparent conducting oxide (TCO) waveguide and a tunable voltage applied across the TCO and a metal layer for modulating an input optical signal. |
FILED | Friday, April 04, 2014 |
APPL NO | 14/246026 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Original (OR) Class G02B 6/1226 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) G02F 1/0356 (20130101) G02F 2203/10 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/932 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494734 | Jain et al. |
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FUNDED BY |
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APPLICANT(S) | Faquir Chand Jain (Storrs, Connecticut); John Zeller (Albany, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | Faquir Chand Jain (Storrs, Connecticut); John Zeller (Albany, New York) |
ABSTRACT | Novel use of a cladded quantum dot array layer serving as a waveguide channel by sandwiching it between two cladding layers comprised of lower index of refraction materials is described to form Si nanophotonic devices and integrated circuits. The photonic device structure is compatible with Si nanoelectronics using conventional, quantum dot gate (QDG), and quantum dot channel (QDC) FET based logic, memories, and other integrated circuits. |
FILED | Monday, July 29, 2013 |
APPL NO | 13/953524 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/10 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/035 (20130101) G02F 1/01708 (20130101) G02F 2001/01791 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/774 (20130101) Y10S 977/932 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494762 | Benner et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Alan F. Benner (Poughkeepsie, New York); Mark A. Brandon (Poughkeepsie, New York); Eric J. McKeever (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York) |
ABSTRACT | Aspects of the present invention include an optical fiber routing mat for routing optical fibers. The optical fiber routing mat includes a first layer of material and a second layer of material. A surface of the first layer of material is adhesively coupled to a surface of the second layer of material. The optical fiber routing mat includes one or more optical fibers disposed between the first layer of material and the second layer of material. The one or more optical fibers are bent to a radius at least large enough to prevent damage to the one or more optical fibers. |
FILED | Wednesday, September 09, 2015 |
APPL NO | 14/849197 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/3608 (20130101) G02B 6/3897 (20130101) G02B 6/4471 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494763 | Benner et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Alan F. Benner (Poughkeepsie, New York); Mark A. Brandon (Poughkeepsie, New York); Eric J. McKeever (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York) |
ABSTRACT | Aspects of the present invention include an optical fiber routing mat for routing optical fibers. The optical fiber routing mat includes a first layer of material and a second layer of material. A surface of the first layer of material is adhesively coupled to a surface of the second layer of material. The optical fiber routing mat includes one or more optical fibers disposed between the first layer of material and the second layer of material. The one or more optical fibers are bent to a radius at least large enough to prevent damage to the one or more optical fibers. |
FILED | Wednesday, February 04, 2015 |
APPL NO | 14/613900 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/3608 (20130101) G02B 6/4478 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494865 | Hinestroza et al. |
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FUNDED BY |
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APPLICANT(S) | Juan P Hinestroza (Ithaca, New York); Huaning Zhu (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Juan P Hinestroza (Ithaca, New York); Huaning Zhu (Ithaca, New York) |
ABSTRACT | Novel polymer monolith structures and methods for fabrication of the same are disclosed in a variety of embodiments. In an illustrative embodiment, a method includes forming a pattern of features on a wafer, thereby forming a patterned wafer; forming a polymer layer on the patterned wafer; using a first plasma to remove at least a portion of the polymer layer; and using a second plasma to etch off at least a portion of the pattern of features, thereby providing a structured polymer monolith. The pattern of features may include an array of pillars. Providing the structured polymer monolith may include providing a structured polymer monolith filter having an array of channels formed by the pillars. The structured polymer monolith may be composed of polypropylene. |
FILED | Friday, December 31, 2010 |
APPL NO | 13/520038 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Separation B01D 39/16 (20130101) B01D 39/1692 (20130101) B01D 67/0034 (20130101) B01D 71/26 (20130101) B01D 2325/08 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502753 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0015 (20130101) G03F 7/20 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495137 | Coetzee et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Peter L. Coetzee (Chester, United Kingdom); Anton V. Riabov (Ann Arbor, Michigan); Octavian Udrea (Valhalla, New York) |
ABSTRACT | Embodiments include methods, and computer program products of an analytical workflow system. Aspects include: observing analytical workflow patterns of one or more users to gather statistics, predicting an analytical workflow and parameter values likely to be requested in future based on the observations according to a compilation policy, applying a parameter generation policy and preparing the predicted analytical workflows according to the compilation policy, and executing analytical workflows and deploying the executed analytical workflows according to a deployment policy. The aspects also include: refining an analytical workflow specification, reusing prepared, executed or deployed analytical workflows, and terminating one or more prepared, executed or deployed analytical workflows when these analytical workflows are unlikely to be requested by a user in the near future according to a termination policy. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/979677 |
ART UNIT | 2199 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 8/443 (20130101) Original (OR) Class G06F 8/4441 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495517 | Ahearn et al. |
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FUNDED BY |
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APPLICANT(S) | Allegheny-Singer Research Institute (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | Allegheny-Singer Research Institute (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Joseph M. Ahearn (Wexford, Pennsylvania); Chau-Ching Liu (Pittsburgh, Pennsylvania); Susan M. Manzi (Wexford, Pennsylvania) |
ABSTRACT | Cell-bound complement activation product (CB-CAP) profiling and scoring serve as diagnostic biomarkers for patients to determine whether a patient who has not met at least four American College of Rheumatology (or similar e.g. SLICC) criteria for a definite Lupus diagnosis should be classified as exhibiting a pre-existing condition that this document refers to as pre-Lupus. |
FILED | Thursday, August 06, 2015 |
APPL NO | 14/820029 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/49 (20130101) G01N 33/564 (20130101) G01N 2800/24 (20130101) Electric Digital Data Processing G06F 19/345 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495594 | Rosario et al. |
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APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Dalton S. Rosario (Germantown, Maryland); Joao M. Romano (Belleville, New Jersey); James P. McCarthy (Nailsworth, Australia) |
ABSTRACT | A methodology for detecting image anomalies in a target area for classifying objects therein, in which at least two images of the target area are obtained from a sensor representing different polarization components. The methodology can be used to classify and/or discriminate manmade objects from natural objects in a target area, for example. A data cube is constructed from the at least two images with the at least two images being aligned, such as on a pixel-wise basis. A processor computes the global covariance of the data cube and thereafter locates a test window over a portion of the data cube. The local covariance of the contents of the test window is computed and objects are classified within the test window when an image anomaly is detected in the test window. For example, an image anomaly may be determined when a matrix determinant ratio of the local covariance and the global covariance exceeds a probability ratio threshold. The window can then be moved, e.g., by one or more pixels to form a new test window in the target area, and the above steps repeated until all of the pixels in the data cube have been included in at least one test window. |
FILED | Thursday, June 05, 2014 |
APPL NO | 14/296653 |
ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/209 (20130101) G06K 9/00624 (20130101) Original (OR) Class G06K 9/6289 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495634 | Modha |
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FUNDED BY |
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APPLICANT(S) | Dharmendra S. Modha (San Jose, California) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Dharmendra S. Modha (San Jose, California) |
ABSTRACT | In one embodiment, the present invention provides a method comprising propagating a first set and a second set of axonal firing events through a symmetric core circuit in a first direction and a second direction, respectively. The symmetric core circuit comprises a first core module and a second core module, and each core module comprises an interconnection network for interconnecting multiple electronic neurons with multiple electronic axons. The method further comprises, for at least one neuron, receiving an axonal firing event via an interconnected axon, and, for at least one neuron, generating a neuronal firing event according to a neuronal activation function. Each core module of the symmetric core circuit has a corresponding adaptive lookup table, the corresponding adaptive lookup table used to determine target axons for neuronal firing events generated by neurons in the core module. |
FILED | Tuesday, August 28, 2012 |
APPL NO | 13/596267 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Electric Digital Data Processing G06F 17/30979 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/04 (20130101) G06N 3/06 (20130101) G06N 3/049 (20130101) G06N 3/061 (20130101) G06N 3/063 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495761 | Gauglitz et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Steffen Gauglitz (Falmouth, Massachusetts); Christopher Michael Sweeney (Santa Barbara, California); Jonathan Daniel Ventura (Colorado Springs, Colorado); Matthew Alan Turk (Santa Barbara, California); Tobias Höllerer (Santa Barbara, California) |
ABSTRACT | Various embodiments each include at least one of systems, methods, devices, and software for environment mapping with automatic motion model selection. One embodiment in the form of a method includes receiving a video frame captured by a camera device into memory and estimating a type of motion from a previously received video frame held in memory to the received video frame. When the type of motion is the same as motion type of a current keyframe group held in memory, the method includes adding the received video frame to the current keyframe group. Conversely, when the type of motion is not the same motion type of the current keyframe group held in memory, the method includes creating a new keyframe group in memory and adding the received video frame to the new keyframe group. |
FILED | Monday, November 03, 2014 |
APPL NO | 14/531608 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0071 (20130101) G06T 7/2033 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495783 | Samarasekera et al. |
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FUNDED BY |
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APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
INVENTOR(S) | Supun Samarasekera (Princeton, New Jersey); Taragay Oskiper (East Windsor, New Jersey); Rakesh Kumar (West Windsor, New Jersey); Mikhail Sizintsev (Plainsboro, New Jersey); Vlad Branzoi (Lawrenceville, New Jersey) |
ABSTRACT | Methods and apparatuses for tracking objects comprise one or more optical sensors for capturing one or more images of a scene, wherein the one or more optical sensors capture a wide field of view and corresponding narrow field of view for the one or more images of a scene, a localization module, coupled to the one or more optical sensors for determining the location of the apparatus, and determining the location of one more objects in the one or more images based on the location of the apparatus and an augmented reality module, coupled to the localization module, for enhancing a view of the scene on a display based on the determined location of the one or more objects. |
FILED | Thursday, June 13, 2013 |
APPL NO | 13/916702 |
ART UNIT | 2617 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/004 (20130101) G06T 11/60 (20130101) Original (OR) Class G06T 19/006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496194 | Arvelo et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Amilcar R. Arvelo (Poughkeepsie, New York); Michael J. Ellsworth (Poughkeepsie, New York); Eric J. McKeever (Poughkeepsie, New York); Thong N. Nguyen (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York) |
ABSTRACT | A method of forming a custom module lid. The method may include placing a multichip module (MCM) between a module base and a temporary lid, target components are exposed through viewing windows in the temporary lid, a top surface of the target components is measured and mapped to create a target profile, the target profile is used to form custom pockets in a custom lid, and the custom pockets correspond to the target components. |
FILED | Friday, November 07, 2014 |
APPL NO | 14/535391 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/06 (20130101) H01L 23/043 (20130101) Original (OR) Class H01L 23/3675 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496229 | Rogers et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | John A. Rogers (Champaign, Illinois); Seung-Kyun Kang (Urbana, Illinois); SukWon Hwang (Urbana, Illinois); Jianjun Cheng (Champaign, Illinois); Yanfeng Zhang (Urbana, Illinois); Hanze Ying (Champaign, Illinois) |
ABSTRACT | The invention provides transient devices, including active and passive devices that physically, chemically and/or electrically transform upon application of at least one internal and/or external stimulus. Incorporation of degradable device components, degradable substrates and/or degradable encapsulating materials each having a programmable, controllable and/or selectable degradation rate provides a means of transforming the device. In some embodiments, for example, transient devices of the invention combine degradable high performance single crystalline inorganic materials with selectively removable substrates and/or encapsulants. |
FILED | Friday, April 11, 2014 |
APPL NO | 14/250671 |
ART UNIT | 2899 — Semiconductors/Memory |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/686 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/44 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0775 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/70 (20130101) H01L 23/06 (20130101) H01L 23/57 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0275 (20130101) H05K 1/0286 (20130101) H05K 1/0306 (20130101) H05K 3/22 (20130101) H05K 3/285 (20130101) H05K 3/287 (20130101) H05K 3/288 (20130101) H05K 5/069 (20130101) H05K 13/0023 (20130101) H05K 2201/10151 (20130101) H05K 2201/10196 (20130101) H05K 2201/10212 (20130101) H05K 2203/175 (20130101) H05K 2203/178 (20130101) H05K 2203/0271 (20130101) H05K 2203/0292 (20130101) H05K 2203/0769 (20130101) H05K 2203/0776 (20130101) H05K 2203/0786 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49124 (20150115) Y10T 137/0318 (20150401) Y10T 428/239 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496315 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | Stephen R. Forrest (Ann Arbor, Michigan); Xin Xu (Ann Arbor, Michigan); Christopher Kyle Renshaw (Ann Arbor, Michigan) |
ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Xin Xu (Ann Arbor, Michigan); Christopher Kyle Renshaw (Ann Arbor, Michigan) |
ABSTRACT | Top-gate, bottom-contact organic thin film transistors are provided. The transistors may include metal bilayer electrodes to aid in charge movement within the device. In an embodiment, an organic transistor includes a drain electrode and a source electrode disposed over a first region of a substrate, a transition metal oxide layer disposed over and in direct physical contact with the drain electrode and the source electrode, an organic preferentially hole conducting channel layer disposed over the metal oxide and between the drain electrode and the source electrode, and a gate electrode disposed over the channel. |
FILED | Thursday, August 19, 2010 |
APPL NO | 12/859496 |
ART UNIT | 2814 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/283 (20130101) H01L 27/307 (20130101) Original (OR) Class H01L 51/0046 (20130101) H01L 51/0078 (20130101) H01L 51/105 (20130101) H01L 51/424 (20130101) H01L 51/0541 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496353 | Chini et al. |
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FUNDED BY |
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APPLICANT(S) | Alessandro Chini (Modena, Italy); Umesh K. Mishra (Montecito, California); Primit Parikh (Goleta, California); Yifeng Wu (Goleta, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Cree, Inc. (Durham, North Carolina) |
INVENTOR(S) | Alessandro Chini (Modena, Italy); Umesh K. Mishra (Montecito, California); Primit Parikh (Goleta, California); Yifeng Wu (Goleta, California) |
ABSTRACT | A process for fabricating single or multiple gate field plates using consecutive steps of dielectric material deposition/growth, dielectric material etch and metal evaporation on the surface of a field effect transistors. This fabrication process permits a tight control on the field plate operation since dielectric material deposition/growth is typically a well controllable process. Moreover, the dielectric material deposited on the device surface does not need to be removed from the device intrinsic regions: this essentially enables the realization of field-plated devices without the need of low-damage dielectric material dry/wet etches. Using multiple gate field plates also reduces gate resistance by multiple connections, thus improving performances of large periphery and/or sub-micron gate devices. |
FILED | Tuesday, October 05, 2010 |
APPL NO | 12/898341 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/0605 (20130101) H01L 29/207 (20130101) H01L 29/402 (20130101) Original (OR) Class H01L 29/404 (20130101) H01L 29/785 (20130101) H01L 29/2003 (20130101) H01L 29/7787 (20130101) H01L 29/41766 (20130101) H01L 29/42312 (20130101) H01L 29/42316 (20130101) H01L 29/66462 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496577 | Arias-Thode et al. |
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FUNDED BY |
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APPLICANT(S) | Yolanda Meriah Arias-Thode (San Diego, California); Lewis Hsu (Lomita, California); Joshua Bianchi (San Diego, California); Ryan John Halonen (San Diego, California); Bart Chadwick (San Diego, California) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Yolanda Meriah Arias-Thode (San Diego, California); Lewis Hsu (Lomita, California); Joshua Bianchi (San Diego, California); Ryan John Halonen (San Diego, California); Bart Chadwick (San Diego, California) |
ABSTRACT | A self-burying microbial fuel cell can include a housing with conductive elements. An anode and cathode can be integrated into the housing at respective proximal and distal ends. A self-burying means for partially burying the microbial fuel cell in a submerged environment is included, so that the anode is buried but the cathode is exposed to the submerged environment can be included. The self-burying means can include omni-directional vibrating device located within the housing, a plurality of intake ports formed in the housing for a pump within the housing. The pump outputs into a longitudinal fluid conduit that extends through the housing and exits at the distal end of the housing. When the vibrating device activates at the same time as the pump, temporary slurry can be formed at the extreme distal end of the device, and the vibrating action causes the microbial fuel cell to become partially buried. |
FILED | Thursday, June 05, 2014 |
APPL NO | 14/297124 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/527 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496595 | Davis et al. |
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FUNDED BY |
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APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Stacy E. Davis (Medway, Massachusetts); Matthew J. Flom (Chesapeake, Virginia); Adam J. Trimby (Sterling, Massachusetts) |
ABSTRACT | A method of raising an antenna includes decoupling an antenna pedestal from an antenna pedestal mounting structure. The method additionally includes separating the antenna pedestal from the antenna pedestal mounting structure. The method further includes inserting one or more antenna lifting fixtures between a first surface of the antenna pedestal and a first surface of the antenna pedestal mounting structure. The method also includes operating the one or more antenna lifting fixtures to move the first surface of the antenna pedestal away from the first surface of the antenna pedestal mounting structure. A corresponding system and antenna lifting fixture are also provided. |
FILED | Thursday, February 04, 2016 |
APPL NO | 15/015714 |
ART UNIT | 3632 — Static Structures, Supports and Furniture |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/125 (20130101) Original (OR) Class H01Q 1/1235 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496674 | Weida et al. |
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FUNDED BY |
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APPLICANT(S) | Daylight Solutions, Inc. (San Diego, California) |
ASSIGNEE(S) | DAYLIGHT SOLUTIONS, INC. (San Diego, California) |
INVENTOR(S) | Miles James Weida (Poway, California); David F. Arnone (Mountain View, California); Eric Kim (San Diego, California); Edeline Fotheringham (San Diego, California) |
ABSTRACT | A laser assembly for generating an output beam includes a first module assembly, a second module assembly, and a module fastener assembly. The second module assembly is selectively movable relative to the first module assembly to selectively adjust a cavity length, and a pivot axis of a grating in the laser. Further, an arm assembly that retains the grating can be adjusted to adjust the cavity length, and to adjust the plane of the grating face. Moreover, the grating is movable relative to the arm assembly to align the grating. |
FILED | Wednesday, August 28, 2013 |
APPL NO | 14/012612 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/08 (20130101) H01S 3/082 (20130101) H01S 3/139 (20130101) H01S 3/08004 (20130101) H01S 3/08009 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497203 | Honig et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Andrew Honig (East Windsor, New Jersey); Andrew Howard (Lansdale, Pennsylvania); Eleazar Eskin (Santa Monica, California); Salvatore J. Stolfo (Ridgewood, New Jersey) |
ABSTRACT | A system and methods for detecting intrusions in the operation of a computer system comprises a sensor configured to gather information regarding the operation of the computer system, to format the information in a data record having a predetermined format, and to transmit the data in the predetermined data format. A data warehouse is configured to receive the data record from the sensor in the predetermined data format and to store the data in a SQL database. A detection model generator is configured to request data records from the data warehouse in the predetermined data format, to generate an intrusion detection model based on said data records, and to transmit the intrusion detection model to the data warehouse according to the predetermined data format. A detector is configured to receive a data record in the predetermined data format from the sensor and to classify the data record in real-time as one of normal operation and an attack based on said intrusion detection model. A data analysis engine is configured to request data records from the data warehouse according to the predetermined data format and to perform a data processing function on the data records. |
FILED | Wednesday, October 08, 2014 |
APPL NO | 14/509208 |
ART UNIT | 2494 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 17/30091 (20130101) G06F 21/554 (20130101) G06F 21/566 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/14 (20130101) Original (OR) Class H04L 63/1416 (20130101) H04L 63/1425 (20130101) H04L 63/1433 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497443 | Sundheimer et al. |
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APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Brent James Sundheimer (Ridgecrest, California); Brandon Catalano (Ridgecrest, California) |
ABSTRACT | A 3-D environment mapping systems and methods of dynamically mapping a 3-D environment includes identifying at least five point correspondences associated with image frames of a scene recorded by a camera from a plurality of viewpoints. A down direction is determined from IMU motion data. The down direction is an absolute global downward direction. Components of the scene that are vertical are identified using the down direction, an iteration of 3-D position of each of the five point correspondences, and a current iteration of refined relative locations and poses of the camera. A 2-D map is generated of the scene by mapping the identified components of the scene in an eagle view of the scene. |
FILED | Tuesday, June 03, 2014 |
APPL NO | 14/294998 |
ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Pictorial Communication, e.g Television H04N 13/0271 (20130101) Original (OR) Class H04N 13/0282 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497843 | Kaganovich et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Dmitri Kaganovich (Potomac, Maryland); Michael H. Helle (Arlington, Virginia); John Palastro (College Park, Maryland); Antonio C. Ting (Silver Spring, Maryland); Daniel F. Gordon (Alexandria, Virginia); Yu-hsin Chen (Fairfax, Virginia) |
ABSTRACT | A plurality of gas jet nozzles having equal angular separation around a central axis eject gas flows towards the central axis. The gas flows collide and form a gas channel from the neutral gas, the gas channel having a gas density depression at the center of the intersecting gas flow, where the gas density depression is surrounded by a higher density gaseous wall along the central axis. Ionization of the gas in the center produces a plasma channel that can guide a laser pulse fired into the gas along the central axis. The geometric arrangement of the gas jets and/or the backing pressure of the gas flows are configured to produce a gas channel having a predetermined density profile such that the ionized gas forms a plasma channel laser guiding structure configured to guide a laser pulse having predetermined spatial parameters. |
FILED | Thursday, May 12, 2016 |
APPL NO | 15/152627 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/00 (20130101) Original (OR) Class H05H 1/24 (20130101) H05H 1/48 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 09492415 | Bankiewicz et al. |
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FUNDED BY |
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APPLICANT(S) | Genzyme Corporation (Framingham, Massachusetts); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | Genzyme Corporation (Framingham, Massachusetts); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Krystof Bankiewicz (Garrett Park, Maryland); Janet Cunningham (Alameda, California) |
ABSTRACT | Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease. |
FILED | Monday, October 08, 2012 |
APPL NO | 13/647155 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Original (OR) Class A61K 35/761 (20130101) A61K 38/45 (20130101) A61K 38/51 (20130101) A61K 45/06 (20130101) A61K 47/48776 (20130101) A61K 48/00 (20130101) A61K 48/0075 (20130101) A61K 51/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/86 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492428 | Hammond et al. |
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FUNDED BY |
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APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky); Cayetano Heredia University (S.M.P. Lima, Peru) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Gerald B. Hammond (Shelbyville, Kentucky); Zhuang Jin (West Palm Beach, Florida); Paula J. Bates (Louisville, Kentucky); Elsa Merit Reyes-Reyes (Prospect, Kentucky); Abraham Vaisberg (Lima, Peru) |
ABSTRACT | Certain embodiments of the invention include compositions comprising a compound of Formula (I), and salts, isomers, and derivatives thereof. Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I), and salts, isomers, and derivatives thereof. Other embodiments of this invention include methods for treating disease (e.g., cancer) and methods for administering a compound of Formula (I), and salts, isomers, and derivatives thereof. |
FILED | Friday, November 16, 2012 |
APPL NO | 14/358731 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/366 (20130101) Original (OR) Class A61K 36/81 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492532 | Korber et al. |
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FUNDED BY |
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APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina); LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico); THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (Birmingham, Alabama); BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina); U. OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (Birmingham, Alabama); BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts); LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, Mexico) |
INVENTOR(S) | Bette T. Korber (Los Alamos, New Mexico); Simon Perkins (Los Alamos, New Mexico); Tanmoy Bhattacharya (Los Alamos, New Mexico); William M. Fischer (Los Alamos, New Mexico); James Theiler (Los Alamos, New Mexico); Norman Letvin (Boston, Massachusetts); Barton F. Haynes (Durham, North Carolina); Beatrice H. Hahn (Birmingham, Alabama); Karina Yusim (Los Alamos, New Mexico); Carla Kuiken (Los Alamos, New Mexico) |
ABSTRACT | The disclosure generally relates to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. |
FILED | Friday, April 17, 2015 |
APPL NO | 14/689957 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16034 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492784 | Christie et al. |
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FUNDED BY |
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APPLICANT(S) | Gervase Maxwell Christie (Amherst, New York); Jonathan A. Lane (Amherst, New York) |
ASSIGNEE(S) | PRAXAIR TECHNOLOGY, INC. (Danbury, Connecticut) |
INVENTOR(S) | Gervase Maxwell Christie (Amherst, New York); Jonathan A. Lane (Amherst, New York) |
ABSTRACT | A method of producing a composite oxygen ion membrane and a composite oxygen ion membrane in which a porous fuel oxidation layer and a dense separation layer and optionally, a porous surface exchange layer are formed on a porous support from mixtures of (Ln1-xAx)wCr1-yByO3-δ and a doped zirconia. In the porous fuel oxidation layer and the optional porous surface exchange layer, A is Calcium and in the dense separation layer A is not Calcium and, preferably is Strontium. Preferred materials are (La0.8Ca0.2)0.95Cr0.5Mn0.5O3-δ for the porous fuel oxidation and optional porous surface exchange layers and (La0.8Sr0.2)0.95Cr0.5Fe0.5O3-δ for the dense separation layer. The use of such materials allows the membrane to sintered in air and without the use of pore formers to reduce membrane manufacturing costs. The use of materials, as described herein, for forming the porous layers have application for forming any type of porous structure, such as a catalyst support. |
FILED | Thursday, July 03, 2014 |
APPL NO | 14/322981 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 53/228 (20130101) Original (OR) Class B01D 67/0041 (20130101) B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/024 (20130101) B01D 71/028 (20130101) B01D 2255/402 (20130101) B01D 2255/407 (20130101) B01D 2255/902 (20130101) B01D 2256/12 (20130101) B01D 2257/104 (20130101) B01D 2258/06 (20130101) B01D 2325/023 (20130101) Non-metallic Elements; Compounds Thereof; C01B 13/0255 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/01 (20130101) C04B 35/04 (20130101) C04B 35/016 (20130101) C04B 35/42 (20130101) C04B 35/44 (20130101) C04B 35/48 (20130101) C04B 35/443 (20130101) C04B 35/462 (20130101) C04B 35/488 (20130101) C04B 35/2633 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/0074 (20130101) C04B 38/0074 (20130101) C04B 38/0074 (20130101) C04B 2111/0081 (20130101) C04B 2111/00612 (20130101) C04B 2111/00801 (20130101) C04B 2235/80 (20130101) C04B 2235/768 (20130101) C04B 2235/3208 (20130101) C04B 2235/3217 (20130101) C04B 2235/3222 (20130101) C04B 2235/3224 (20130101) C04B 2235/3225 (20130101) C04B 2235/3227 (20130101) C04B 2235/3229 (20130101) C04B 2235/3232 (20130101) C04B 2235/3234 (20130101) C04B 2235/3243 (20130101) C04B 2235/3246 (20130101) C04B 2235/3262 (20130101) C04B 2235/3268 (20130101) C04B 2235/3272 (20130101) C04B 2235/3274 (20130101) C04B 2235/3275 (20130101) C04B 2235/5445 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1314 (20150115) Y10T 428/24997 (20150401) Y10T 428/24999 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492795 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Wei Liu (Richland, Washington); Nathan L. Canfield (Richland, Washington) |
ABSTRACT | A membrane device and processes for fabrication and for using are disclosed. The membrane device may include a number of porous metal membranes that provide a high membrane surface area per unit volume. The membrane device provides various operation modes that enhance throughput and selectivity for mass exchange, mass transfer, separation, and/or filtration applications between feed flow streams and permeate flow streams. |
FILED | Thursday, February 20, 2014 |
APPL NO | 14/185706 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 53/02 (20130101) B01D 53/228 (20130101) B01D 53/268 (20130101) B01D 61/02 (20130101) B01D 61/14 (20130101) B01D 63/081 (20130101) B01D 63/082 (20130101) B01D 63/084 (20130101) B01D 63/085 (20130101) B01D 65/02 (20130101) B01D 71/022 (20130101) Original (OR) Class B01D 71/028 (20130101) B01D 2253/108 (20130101) B01D 2257/504 (20130101) B01D 2311/13 (20130101) B01D 2315/10 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/14 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492969 | Spadaccini et al. |
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FUNDED BY |
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APPLICANT(S) | Christopher M. Spadaccini (Oakland, California); George Farquar (Livermore, California); Todd Weisgraber (Brentwood, California); Steven Gemberling (Livermore, California); Nicholas Fang (Champaign, Illinois); Jun Xu (Urbana, Illinois); Matthew Alonso (Freeport, Illinois); Howon Lee (Urbana, Illinois) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Christopher M. Spadaccini (Oakland, California); George Farquar (Livermore, California); Todd Weisgraber (Brentwood, California); Steven Gemberling (Livermore, California); Nicholas Fang (Champaign, Illinois); Jun Xu (Urbana, Illinois); Matthew Alonso (Freeport, Illinois); Howon Lee (Urbana, Illinois) |
ABSTRACT | A high-resolution PμSL system and method incorporating one or more of the following features with a standard PμSL system using a SLM projected digital image to form components in a stereolithographic bath: a far-field superlens for producing sub-diffraction-limited features, multiple spatial light modulators (SLM) to generate spatially-controlled three-dimensional interference holograms with nanoscale features, and the integration of microfluidic components into the resin bath of a PμSL system to fabricate microstructures of different materials. |
FILED | Tuesday, May 31, 2011 |
APPL NO | 13/149773 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/0051 (20130101) Original (OR) Class B29C 67/0062 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) G02B 27/56 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70408 (20130101) G03F 7/70416 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/2294 (20130101) G03H 2001/0094 (20130101) G03H 2225/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493349 | Varma et al. |
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FUNDED BY |
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APPLICANT(S) | Arvind Varma (West Lafayette, Indiana); Hyun Tae Hwang (West Lafayette, Indiana); Ahmad Al-Kukhun (Beaverton, Oregon) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Arvind Varma (West Lafayette, Indiana); Hyun Tae Hwang (West Lafayette, Indiana); Ahmad Al-Kukhun (Beaverton, Oregon) |
ABSTRACT | A system for generating and purifying hydrogen. To generate hydrogen, the system includes inlets configured to receive a hydrogen carrier and an inert insulator, a mixing chamber configured to combine the hydrogen carrier and the inert insulator, a heat exchanger configured to apply heat to the mixture of hydrogen carrier and the inert insulator, wherein the applied heat results in the generation of hydrogen from the hydrogen carrier, and an outlet configured to release the generated hydrogen. To purify hydrogen, the system includes a primary inlet to receive a starting material and an ammonia filtration subassembly, which may include an absorption column configured to absorb the ammonia into water for providing purified hydrogen at a first purity level. The ammonia filtration subassembly may also include an adsorbent member configured to adsorb ammonia from the starting material into an adsorbent for providing purified hydrogen at a second purity level. |
FILED | Sunday, September 02, 2012 |
APPL NO | 14/342261 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/04 (20130101) Original (OR) Class C01B 2203/066 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0606 (20130101) H01M 8/0662 (20130101) H01M 8/0687 (20130101) H01M 8/04067 (20130101) H01M 8/04164 (20130101) H01M 8/04291 (20130101) H01M 2008/1095 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Y02E 60/364 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493397 | Coates et al. |
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FUNDED BY |
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APPLICANT(S) | Geoffrey W. Coates (Lansing, New York); Henry A. Kostalik, IV (Minneapolis, Minnesota); Timothy J. Clark (Kingston, Canada); Nicholas J. Robertson (Ashland, Wisconsin) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Geoffrey W. Coates (Lansing, New York); Henry A. Kostalik, IV (Minneapolis, Minnesota); Timothy J. Clark (Kingston, Canada); Nicholas J. Robertson (Ashland, Wisconsin) |
ABSTRACT | Ionomers comprising ionic groups such as, for example, tetraalkylammonium groups and methods of making such ionomers. For example, the ionomers can be produced by ring opening metathesis polymerization of alkene-containing monomers with tetraalkylammonium groups and, optionally, alkene-containing monomers without tetraalkylammonium groups. The ionomers can be used in applications such as, for example, fuel cell applications. |
FILED | Monday, May 31, 2010 |
APPL NO | 13/322306 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 211/63 (20130101) Original (OR) Class C07C 2101/18 (20130101) C07C 2102/42 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/103 (20130101) H01M 8/1011 (20130101) H01M 8/1023 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/523 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493526 | Cary et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Stephen P. L. Cary (San Mateo, California); Elizabeth M. Boon (Stony Brook, New York); Emily Weinert (Berkeley, California); Jonathan A. Winger (Oakland, California); Michael A. Marletta (La Jolla, California) |
ABSTRACT | H-NOX proteins are mutated to exhibit improved or optimal kinetic and thermodynamic properties for blood gas O2 delivery. The engineered H-NOX proteins comprise mutations that impart altered O2 or NO ligand-binding relative to the corresponding wild-type H-NOX domain, and are operative as physiologically compatible mammalian blood O2 gas carriers. The invention also provides pharmaceutical compositions, kits, and methods that use wild-type or mutant H-NOX proteins for the treatment of any condition for which delivery of O2 is beneficial. |
FILED | Wednesday, September 17, 2014 |
APPL NO | 14/489395 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/33 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/195 (20130101) C07K 14/435 (20130101) C07K 14/43545 (20130101) C07K 14/43563 (20130101) C07K 14/43581 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/102499 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493527 | Cary et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Stephen P. L. Cary (San Mateo, California); Elizabeth M. Boon (Stony Brook, New York); Jonathan A. Winger (Oakland, California); Michael A. Marletta (La Jolla, California) |
ABSTRACT | H-NOX proteins are mutated to exhibit improved or optimal kinetic and thermodynamic properties for blood gas NO delivery. The engineered H-NOX proteins comprise mutations that impart altered NO or O2 ligand-binding relative to the corresponding wild-type H-NOX domain, and are operative as physiologically compatible mammalian blood NO gas carriers. The invention also provides pharmaceutical compositions, kits, and methods that use wild-type or mutant H-NOX proteins for the treatment of any condition for which delivery of NO is beneficial. |
FILED | Thursday, September 18, 2014 |
APPL NO | 14/490597 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/33 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/195 (20130101) C07K 14/435 (20130101) C07K 14/43545 (20130101) C07K 14/43563 (20130101) C07K 14/43581 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/102499 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493695 | Ram et al. |
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FUNDED BY |
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APPLICANT(S) | Manoj Kumar Ram (Palm Harbor, Florida); Chand K. Jotshi (Gainesville, Florida); Elias K. Stefanakos (Tampa, Florida); Dharendra Yogi Goswami (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Manoj Kumar Ram (Palm Harbor, Florida); Chand K. Jotshi (Gainesville, Florida); Elias K. Stefanakos (Tampa, Florida); Dharendra Yogi Goswami (Tampa, Florida) |
ABSTRACT | Storage systems based on latent heat storage have high-energy storage density, which reduces the footprint of the system and the cost. However, phase change materials (PCMs), such as NaNO3, NaCl, KNO3, have very low thermal conductivities. To enhave the storage of PCMs, macroencapsulation of PCMs was performed using a metal oxide, such as SiO2 or a graphene-SiO2, over polyimide-coated or nickel-embedded, polyimide-coated pellets The macro encapsulation provides a self-supporting structure, enhances the heat transfer rate, and provides a cost effective and reliable solution for thermal energy storage for use in solar thermal power plants. NaNO3 was selected for thermal storage in a temperature range of 300° C. to 500° C. The PCM was encapsulated in a metal oxide cell using self-assembly reactions, hydrolysis, and simultaneous chemical oxidation at various temperatures. |
FILED | Tuesday, January 21, 2014 |
APPL NO | 14/159874 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1035 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/08 (20130101) C08K 3/10 (20130101) C08K 3/16 (20130101) C08K 3/28 (20130101) C08K 2003/0862 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/063 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493783 | Wilkerson et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin); Board of Trustees of Michigan State University (East Lansing, Michigan); The University of British Columbia (Vancouver, Canada) |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); The University of British Columbia (, Canada); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Curtis Wilkerson (Swartz Creek, Michigan); John Ralph (Madison, Wisconsin); Saunia Withers (Durham, North Carolina); Shawn D. Mansfield (Vancouver, Canada) |
ABSTRACT | The invention relates to isolated nucleic acids encoding a feruloyl-CoA:monolignol transferase and feruloyl-CoA:monolignol transferase enzymes. The isolated nucleic acids and/or the enzymes enable incorporation of monolignol ferulates into the lignin of plants, where such monolignol ferulates include, for example, p-coumaryl ferulate, coniferyl ferulate, and/or sinapyl ferulate. The invention also includes methods and plants that include nucleic acids encoding a feruloyl-CoA:monolignol transferase enzyme and/or feruloyl-CoA:monolignol transferase enzymes. |
FILED | Thursday, October 04, 2012 |
APPL NO | 14/349137 |
ART UNIT | 1662 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) C12N 15/8243 (20130101) Original (OR) Class C12N 15/8255 (20130101) Enzymes C12Y 203/01133 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493793 | Jessen et al. |
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FUNDED BY |
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APPLICANT(S) | Holly J. Jessen (Chanhassen, Minnesota); Jian Yi (Carlsbad, California) |
ASSIGNEE(S) | Cargill, Incorporated (Wayzata, Minnesota) |
INVENTOR(S) | Holly J. Jessen (Chanhassen, Minnesota); Jian Yi (Carlsbad, California) |
ABSTRACT | The present application discloses the identification of novel I. orientalis ADH1, ADHa, and ADHb genes, and the production and characterization of genetically modified yeast cells in which these genes were altered. Provided herein are isolated I. orientalis ADH1, ADHa, and ADHb polynucleotides and polypeptides, genetically modified yeast cells that overexpress I. orientalis ADH1 and/or contain deletions or disruptions of ADHa and/or ADHb, and methods of using culturing these modified cells to produce ethanol. |
FILED | Tuesday, November 22, 2011 |
APPL NO | 13/988899 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) Original (OR) Class C12P 7/10 (20130101) C12P 7/065 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493799 | Coelho et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Pedro S. Coelho (Los Angeles, California); Eric M. Brustad (Durham, North Carolina); Frances H. Arnold (La Canada, California); Zhan Wang (San Jose, California); Jared C. Lewis (Chicago, Illinois) |
ABSTRACT | The present invention provides methods for catalyzing the conversion of an olefin to any compound containing one or more cyclopropane functional groups using heme enzymes. In certain aspects, the present invention provides a method for producing a cyclopropanation product comprising providing an olefinic substrate, a diazo reagent, and a heme enzyme; and admixing the components in a reaction for a time sufficient to produce a cyclopropanation product. In other aspects, the present invention provides heme enzymes including variants and fragments thereof that are capable of carrying out in vivo and in vitro olefin cyclopropanation reactions. Expression vectors and host cells expressing the heme enzymes are also provided by the present invention. |
FILED | Wednesday, February 18, 2015 |
APPL NO | 14/625449 |
ART UNIT | 1671 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) C12P 13/02 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493851 | Jansen et al. |
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FUNDED BY |
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APPLICANT(S) | VIRDIA LTD (Herzelia, Israel); VIRDIA, INC. (Danville, Virginia) |
ASSIGNEE(S) | Virdia, Inc. (Raceland, Louisiana) |
INVENTOR(S) | Robert Jansen (Redwood City, California); Claire Gregoire (Verrieres le Buisson, France); Philip Travisano (Danville, Virginia); Lee Madsen (Manassas, Virginia); Neta Matis (Hod Hasharon, Israel); Yael Har-Tal (Herzaliya, Israel); Shay Eliahu (Ramat Efal, Israel); James Alan Lawson (Ellsworth, Maine); Noa Lapidot (Mevaseret Zion, Israel); Aharon M. Eyal (Jerusalem, Israel); Timothy Allen Bauer (Belleville, Illinois); Hagit Sade (Ramat Gan, Israel); Paul McWilliams (Racine, Wisconsin); Michael Zviely (Haifa, Israel); Adam Carden (Henderson, North Carolina) |
ABSTRACT | The present invention relates to methods of processing lignocellulosic material to obtain hemicellulose sugars, cellulose sugars, lignin, cellulose and other high-value products. Also provided are hemicellulose sugars, cellulose sugars, lignin, cellulose, and other high-value products. |
FILED | Friday, May 03, 2013 |
APPL NO | 14/398444 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Compounds of Unknown Constitution C07G 1/00 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) C10L 1/023 (20130101) C10L 1/026 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2201/00 (20130101) C12P 2203/00 (20130101) Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 1/02 (20130101) C13K 1/04 (20130101) C13K 13/002 (20130101) C13K 13/007 (20130101) Original (OR) Class Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor D21C 11/0007 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/13 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493948 | Davidson et al. |
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FUNDED BY |
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APPLICANT(S) | Jane Davidson (Edina, Minnesota); Susan Mantell (St. Paul, Minnesota); Louise Goldberg (Minneapolis, Minnesota); John Carmody (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
INVENTOR(S) | Jane Davidson (Edina, Minnesota); Susan Mantell (St. Paul, Minnesota); Louise Goldberg (Minneapolis, Minnesota); John Carmody (Minneapolis, Minnesota) |
ABSTRACT | A self-supporting panel is used to form building components, including roofs that have no independent supports for the panels between the ends of the panels. The panel system includes a base support or structural component having a top face sheet supported by longitudinally load carrying webs and a layer of insulation on the exterior of the face sheet. The insulation spans the entire face sheet to overlie connectors between the edges of adjacent panels when the panels are assembled to form a wall or roof, to eliminate thermal shorts. |
FILED | Friday, September 14, 2007 |
APPL NO | 11/901280 |
ART UNIT | 3635 — Static Structures, Supports and Furniture |
CURRENT CPC | Structural Elements; Building Materials E04C 2/50 (20130101) Original (OR) Class Roof Coverings; Sky-lights; Gutters; Roof-working Tools E04D 3/357 (20130101) E04D 11/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494011 | Lowry et al. |
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FUNDED BY |
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APPLICANT(S) | OLYMPIC RESEARCH, INC. (Port Townsend, Washington) |
ASSIGNEE(S) | Olympic Research, Inc. (Port Townsend, Washington) |
INVENTOR(S) | William Edward Lowry (Port Townsend, Washington); Sandra Dalvit Dunn (Santa Fe, New Mexico) |
ABSTRACT | A platform is formed in a well below a target plug zone by lowering a thermite reaction charge into the well and igniting it, whereby the products of the reaction are allowed to cool and expand to form a platform or support in the well. A main thermite reaction charge is placed above the platform and ignited to form a main sealing plug for the well. In some embodiments an upper plug is formed by igniting an upper thermite reaction charge above the main thermite reaction charge. The upper plug confines the products of ignition of the main thermite reaction charge. |
FILED | Friday, July 08, 2016 |
APPL NO | 15/205176 |
ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/426 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 33/12 (20130101) E21B 33/13 (20130101) Original (OR) Class E21B 36/008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09494168 — Energy efficient fluid powered linear actuator with variable area and concentric chambers
US 09494168 | Lind et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Randall F. Lind (Loudon, Tennessee); Lonnie J. Love (Knoxville, Tennessee) |
ABSTRACT | Hydraulic actuation systems having concentric chambers, variable displacements and energy recovery capabilities include cylinders with pistons disposed inside of barrels. When operating in energy consuming modes, high speed valves pressurize extension chambers or retraction chambers to provide enough force to meet or counteract an opposite load force. When operating in energy recovery modes, high speed valves return a working fluid from extension chambers or retraction chambers, which are pressurized by a load, to an accumulator for later use. |
FILED | Tuesday, August 26, 2014 |
APPL NO | 14/468629 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 11/006 (20130101) Original (OR) Class F15B 11/036 (20130101) F15B 21/14 (20130101) F15B 2211/88 (20130101) F15B 2211/625 (20130101) F15B 2211/761 (20130101) F15B 2211/6336 (20130101) F15B 2211/7055 (20130101) F15B 2211/7107 (20130101) F15B 2211/30575 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494464 | Kotter |
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FUNDED BY |
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APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Dale K. Kotter (Shelley, Idaho) |
ABSTRACT | Terahertz imaging devices may comprise a focal plane array including a substrate and a plurality of resonance elements. The plurality of resonance elements may comprise a conductive material coupled to the substrate. Each resonance element of the plurality of resonance elements may be configured to resonate and produce an output signal responsive to incident radiation having a frequency between about a 0.1 THz and 4 THz range. A method of detecting a hazardous material may comprise receiving incident radiation by a focal plane array having a plurality of discrete pixels including a resonance element configured to absorb the incident radiation at a resonant frequency in the THz, generating an output signal from each of the discrete pixels, and determining a presence of a hazardous material by interpreting spectral information from the output signal. |
FILED | Wednesday, February 20, 2013 |
APPL NO | 13/771871 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Original (OR) Class G01J 5/023 (20130101) G01J 5/0837 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3581 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 8/005 (20130101) Antennas, i.e Radio Aerials H01Q 9/27 (20130101) H01Q 21/062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494478 | Ivanov et al. |
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FUNDED BY |
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APPLICANT(S) | UT-BATTELLE LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Ilia N. Ivanov (Knoxville, Tennessee); David B. Geohegan (Knoxville, Tennessee) |
ABSTRACT | The present invention, in one embodiment, provides a method of measuring pressure or temperature using a sensor including a sensor element composed of a plurality of carbon nanotubes. In one example, the resistance of the plurality of carbon nanotubes is measured in response to the application of temperature or pressure. The changes in resistance are then recorded and correlated to temperature or pressure. In one embodiment, the present invention provides for independent measurement of pressure or temperature using the sensors disclosed herein. |
FILED | Tuesday, September 24, 2013 |
APPL NO | 14/035080 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/00 (20130101) G01K 7/18 (20130101) G01K 7/021 (20130101) G01K 7/028 (20130101) G01K 2211/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/20 (20130101) G01L 9/00 (20130101) G01L 9/0001 (20130101) G01L 9/0002 (20130101) G01L 9/0005 (20130101) G01L 19/00 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) Y10S 977/955 (20130101) Y10S 977/956 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494490 | Tralshawala et al. |
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FUNDED BY |
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APPLICANT(S) | Nilesh Tralshawala (Rexford, New York); Harold Edward Miller (Glenville, New York); Vivek Venugopal Badami (Schenectady, New York); Sameer Vittal (Atlanta, Georgia); Daniel White Sexton (Niskayuna, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Nilesh Tralshawala (Rexford, New York); Harold Edward Miller (Glenville, New York); Vivek Venugopal Badami (Schenectady, New York); Sameer Vittal (Atlanta, Georgia); Daniel White Sexton (Niskayuna, New York) |
ABSTRACT | A creep life management system includes at least one sensor apparatus coupled to a first component. The at least one sensor apparatus is configured with a unique identifier. The creep life management system also includes at least one reader unit coupled to a second component. The at least one reader unit is configured to transmit an interrogation request signal to the at least one sensor apparatus and receive a measurement response signal transmitted from the at least one sensor apparatus. The creep life management system further includes at least one processor programmed to determine a real-time creep profile of the first component as a function of the measurement response signal transmitted from the at least one sensor apparatus. |
FILED | Tuesday, August 14, 2012 |
APPL NO | 13/585194 |
ART UNIT | 2864 — Printing/Measuring and Testing |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/04 (20130101) F01D 21/003 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/332 (20130101) F05D 2270/808 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2203/0071 (20130101) G01N 2203/0244 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494509 | Graves et al. |
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FUNDED BY |
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APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Steven W. Graves (San Juan Pueblo, New Mexico); Robert C. Habbersett (Santa Fe, New Mexico) |
ABSTRACT | A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals. |
FILED | Friday, May 16, 2014 |
APPL NO | 14/280053 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) Original (OR) Class G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 21/53 (20130101) G01N 2015/1413 (20130101) G01N 2015/1493 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494518 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | Haw Yang (Princeton Junction, New Jersey); Kevin Welsher (Plainsboro, New Jersey) |
ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | Haw Yang (Princeton Junction, New Jersey); Kevin Welsher (Plainsboro, New Jersey) |
ABSTRACT | A system and method for non-invasively tracking a particle in a sample is disclosed. The system includes a 2-photon or confocal laser scanning microscope (LSM) and a particle-holding device coupled to a stage with X-Y and Z position control. The system also includes a tracking module having a tracking excitation laser, X-Y and Z radiation-gathering components configured to detect deviations of the particle in an X-Y and Z directions. The system also includes a processor coupled to the X-Y and Z radiation gathering components, generate control signals configured to drive the stage X-Y and Z position controls to track the movement of the particle. The system may also include a synchronization module configured to generate LSM pixels stamped with stage position and a processing module configured to generate a 3D image showing the 3D trajectory of a particle using the LSM pixels stamped with stage position. |
FILED | Thursday, July 18, 2013 |
APPL NO | 14/415779 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1475 (20130101) G01N 21/6458 (20130101) Original (OR) Class Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 90/00 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0024 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494787 | Bagwell |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Brett Bagwell (Albuquerque, New Mexico) |
ABSTRACT | A direct view telescopic sight includes objective lens, eyepiece, and prism erector assemblies. The objective lens assembly is mounted to receive light of an image from an object direction and direct the light along an optical path. The eyepiece assembly is mounted to receive the light along the optical path and to emit the light of the image along an eye-ward direction. The prism erector assembly is positioned between the objective lens and eyepiece assemblies and includes first and second prism elements through which the optical path passes. The first and second prism elements invert the image. A reticle element is disposed on or adjacent to a surface of one of the first or second prism elements to combine a reticle on the image. The image is brought into focus at only a single focal plane between the objective lens and eyepiece assemblies at a given time. |
FILED | Tuesday, March 12, 2013 |
APPL NO | 13/797607 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 23/145 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495131 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Dong Chen (Yorktown Heights, New York); Noel A. Eisley (Wappingers Falls, New York); Philip Heidelberger (Yorktown Heights, New York); Burkhard Steinmacher-Burow (Boeblingen, Germany) |
ABSTRACT | To add floating point numbers in a parallel computing system, a collective logic device receives the floating point numbers from computing nodes. The collective logic devices converts the floating point numbers to integer numbers. The collective logic device adds the integer numbers and generating a summation of the integer numbers. The collective logic device converts the summation to a floating point number. The collective logic device performs the receiving, the converting the floating point numbers, the adding, the generating and the converting the summation in one pass. One pass indicates that the computing nodes send inputs only once to the collective logic device and receive outputs only once from the collective logic device. |
FILED | Monday, March 09, 2015 |
APPL NO | 14/641765 |
ART UNIT | 2184 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 7/38 (20130101) Original (OR) Class G06F 7/485 (20130101) G06F 9/3885 (20130101) G06F 9/30014 (20130101) G06F 9/30025 (20130101) G06F 2207/3808 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495274 | Antao et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Samuel F. Antao (Somerville, Massachusetts); Carlo Bertolli (Dobbs Ferry, New York); Alexandre E. Eichenberger (Chappaqua, New York); John K. O'Brien (South Salem, New York) |
ABSTRACT | A computer-implemented method includes selecting a runtime for executing a program. The runtime includes a first combination of feature implementations, where each feature implementation implements a feature of an application programming interface (API). Execution of the program is monitored, and the execution uses the runtime. Monitor data is generated based on the monitoring. A second combination of feature implementations are selected, by a computer processor, where the selection is based at least in part on the monitor data. The runtime is modified by activating the second combination of feature implementations to replace the first combination of feature implementations. |
FILED | Monday, November 30, 2015 |
APPL NO | 14/953651 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/54 (20130101) G06F 11/302 (20130101) G06F 11/3409 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495866 | Roth et al. |
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FUNDED BY |
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APPLICANT(S) | General Motors LLC (Detroit, Michigan) |
ASSIGNEE(S) | General Motors LLC (Detroit, Michigan) |
INVENTOR(S) | Rebecca C. Roth (Novi, Michigan); Paul H. Pebbles (Novi, Michigan) |
ABSTRACT | A method of communicating with residential electrical devices using a vehicle telematics unit includes receiving information identifying a residential electrical device to control; displaying in a vehicle one or more controlled features of the identified residential electrical device; receiving from a vehicle occupant a selection of the displayed controlled features of the residential electrical device; sending an instruction from the vehicle telematics unit to the residential electrical device via a wireless carrier system in response to the received selection; and controlling the residential electrical device using the sent instruction. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/803217 |
ART UNIT | 2686 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Transmission Systems for Measured Values, Control or Similar Signals G08C 17/02 (20130101) Original (OR) Class G08C 2201/31 (20130101) G08C 2201/91 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/2818 (20130101) H04L 2012/2841 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496058 | Marquino et al. |
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FUNDED BY |
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APPLICANT(S) | Wayne Marquino (Wilmington, North Carolina); Stephan C. Moen (Wilmington, North Carolina); Richard M. Wachowiak (Wilmington, North Carolina); John L. Gels (Wilmington, North Carolina); Jesus Diaz-Quiroz (Wilmington, North Carolina); John C. Burns, Jr. (Wilmington, North Carolina) |
ASSIGNEE(S) | GE-HITACHI NUCLEAR ENERGY AMERICAS LLC (Wilmington, North Carolina) |
INVENTOR(S) | Wayne Marquino (Wilmington, North Carolina); Stephan C. Moen (Wilmington, North Carolina); Richard M. Wachowiak (Wilmington, North Carolina); John L. Gels (Wilmington, North Carolina); Jesus Diaz-Quiroz (Wilmington, North Carolina); John C. Burns, Jr. (Wilmington, North Carolina) |
ABSTRACT | Systems passively eliminate noncondensable gasses from facilities susceptible to damage from combustion of built-up noncondensable gasses, such as H2 and O2 in nuclear power plants, without the need for external power and/or moving parts. Systems include catalyst plates installed in a lower header of the Passive Containment Cooling System (PCCS) condenser, a catalyst packing member, and/or a catalyst coating on an interior surface of a condensation tube of the PCCS condenser or an annular outlet of the PCCS condenser. Structures may have surfaces or hydrophobic elements that inhibit water formation and promote contact with the noncondensable gas. Noncondensable gasses in a nuclear power plant are eliminated by installing and using the systems individually or in combination. An operating pressure of the PCCS condenser may be increased to facilitate recombination of noncondensable gasses therein. |
FILED | Monday, November 17, 2014 |
APPL NO | 14/543286 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Separation B01D 53/8671 (20130101) B01D 2255/1023 (20130101) B01D 2255/1025 (20130101) B01D 2257/108 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 12/007 (20130101) B01J 23/40 (20130101) B01J 35/04 (20130101) Nuclear Reactors G21C 9/06 (20130101) G21C 19/303 (20130101) Original (OR) Class G21C 19/317 (20130101) G21C 21/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496073 | Shen |
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FUNDED BY |
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APPLICANT(S) | Tengming Shen (Naperville, Illinois) |
ASSIGNEE(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
INVENTOR(S) | Tengming Shen (Naperville, Illinois) |
ABSTRACT | A method, system, and apparatus for fabricating a high-strength Superconducting cable comprises pre-oxidizing at least one high-strength alloy wire, coating at least one Superconducting wire with a protective layer, and winding the high-strength alloy wire and the Superconducting wire to form a high-strength Superconducting cable. |
FILED | Tuesday, April 02, 2013 |
APPL NO | 13/855190 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/02 (20130101) H01B 12/08 (20130101) Original (OR) Class H01B 12/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/143 (20130101) H01L 39/248 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 40/641 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49014 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496127 | Owen et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Benjamin C. Owen (West Lafayette, Indiana); Hilkka I. Kenttamaa (West Lafayette, Indiana) |
ABSTRACT | The present disclosure provides a new tandem mass spectrometer and methods of using the same for analyzing charged particles. The differentially pumped dual linear quadrupole ion trap mass spectrometer of the present disclose includes a combination of two linear quadrupole (LQIT) mass spectrometers with differentially pumped vacuum chambers. |
FILED | Tuesday, September 15, 2015 |
APPL NO | 14/854801 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/004 (20130101) H01J 49/24 (20130101) H01J 49/422 (20130101) H01J 49/4225 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496426 | Barnes et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Teresa M. Barnes (Evergreen, Colorado); James Burst (Lakewood, Colorado) |
ABSTRACT | A thin film photovoltaic device (100) with a tunable, minimally conductive buffer (128) layer is provided. The photovoltaic device (100) may include a back contact (150), a transparent front contact stack (120), and an absorber (140) positioned between the front contact stack (120) and the back contact (150). The front contact stack (120) may include a low resistivity transparent conductive oxide (TCO) layer (124) and a buffer layer (128) that is proximate to the absorber layer (140). The photovoltaic device (100) may also include a window layer (130) between the buffer layer (128) and the absorber (140). In some cases, the buffer layer (128) is minimally conductive, with its resistivity being tunable, and the buffer layer (128) may be formed as an alloy from a host oxide and a high-permittivity oxide. The high-permittivity oxide may further be chosen to have a bandgap greater than the host oxide. |
FILED | Tuesday, February 05, 2013 |
APPL NO | 14/377763 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/073 (20130101) H01L 31/0749 (20130101) H01L 31/1828 (20130101) H01L 31/1836 (20130101) H01L 31/1884 (20130101) H01L 31/02167 (20130101) Original (OR) Class H01L 31/022466 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/541 (20130101) Y02E 10/543 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496448 | Cruz-Campa et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Jose Luis Cruz-Campa (Albuquerque, New Mexico); Gregory N. Nielson (Albuquerque, New Mexico); Murat Okandan (Edgewood, New Mexico); Anthony L. Lentine (Albuquerque, New Mexico); Paul J. Resnick (Albuquerque, New Mexico); Vipin P. Gupta (Reno, Nevada) |
ABSTRACT | Photovoltaic cells and photovoltaic modules, as well as methods of making and using such photovoltaic cells and photovoltaic modules, are disclosed. More particularly, embodiments of the photovoltaic cells selectively reflect visible light to provide the photovoltaic cells with a colorized appearance. Photovoltaic modules combining colorized photovoltaic cells may be used to harvest solar energy while providing a customized appearance, e.g., an image or pattern. |
FILED | Wednesday, October 30, 2013 |
APPL NO | 14/067822 |
ART UNIT | 1758 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02 (20130101) H01L 31/18 (20130101) Original (OR) Class H01L 31/042 (20130101) H01L 31/0682 (20130101) H01L 31/02168 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/547 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496590 | Vajda et al. |
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FUNDED BY |
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APPLICANT(S) | Stefan Vajda (Lisle, Illinois); Larry A. Curtiss (Downers Grove, Illinois); Jun Lu (Bolingbrook, Illinois); Khalil Amine (Oakbrook, Illinois); Eric C. Tyo (Lisle, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Stefan Vajda (Lisle, Illinois); Larry A. Curtiss (Downers Grove, Illinois); Jun Lu (Bolingbrook, Illinois); Khalil Amine (Oakbrook, Illinois); Eric C. Tyo (Lisle, Illinois) |
ABSTRACT | The invention provides a method for generating Li2O2 or composites of it, the method uses mixing lithium ions with oxygen ions in the presence of a catalyst. The catalyst comprises a plurality of metal clusters, their alloys and mixtures, each cluster consisting of between 3 and 18 metal atoms. The invention also describes a lithium-air battery which uses a lithium metal anode, and a cathode opposing the anode. The cathode supports metal clusters, each cluster consisting of size selected clusters, taken from a range of between approximately 3 and approximately 18 metal atoms, and an electrolyte positioned between the anode and the cathode. |
FILED | Monday, September 30, 2013 |
APPL NO | 14/042203 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/382 (20130101) H01M 4/9058 (20130101) H01M 12/08 (20130101) Original (OR) Class H01M 2220/20 (20130101) H01M 2300/0028 (20130101) H01M 2300/0037 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496702 | Dong et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Dong Dong (Schenectady, New York); Luis Jose Garces (Niskayuna, New York); Rixin Lai (Clifton Park, New York); Song Chi (Clifton Park, New York); Maja Harfman Todorovic (Niskayuna, New York); Di Zhang (Niskayuna, New York) |
ABSTRACT | A method and a high-voltage DC (HVDC) power system are provided. The system includes a plurality of sending-end (SE) modules coupled in electrical series and divided into at least two groups that each operate independently with respect to an electrical ground and a plurality of receiving-end (RE) power converter modules electrically coupled to the plurality of SE modules, the plurality of RE power converter modules including a fast ground-fault detection and control device, the plurality of RE power converter modules including a receiving-end front-end DC-DC converter controller, and an output current damping control. |
FILED | Monday, July 15, 2013 |
APPL NO | 13/941657 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 41/0085 (20130101) Emergency Protective Circuit Arrangements H02H 3/16 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/36 (20130101) H02J 2003/365 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/60 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/305 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496746 | Mi et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents Of The University Of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Chris Mi (Detroit, Michigan); Siqi Li (Dearborn, Michigan); Trong-Duy Nguyen (Dearborn, Michigan); Junhua Wang (Dearborn Heights, Michigan); Jiangui Li (Dearborn Heights, Michigan); Weihan Li (Westland, Michigan); Jun Xu (Inkster, Michigan) |
ABSTRACT | A wireless power transmission system is provided for high power applications. The power transmission system is comprised generally of a charging unit configured to generate an alternating electromagnetic field and a receive unit configured to receive the alternating electromagnetic field from the charging unit. The charging unit includes a power source; an input rectifier; an inverter; and a transmit coil. The transmit coil has a spirangle arrangement segmented into n coil segments with capacitors interconnecting adjacent coil segments. The receive unit includes a receive coil and an output rectifier. The receive coil also has a spirangle arrangement segmented into m coil segments with capacitors interconnecting adjacent coil segments. |
FILED | Wednesday, May 14, 2014 |
APPL NO | 14/277288 |
ART UNIT | 2859 — Printing/Measuring and Testing |
CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/1829 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 3/10 (20130101) H01F 27/40 (20130101) H01F 27/2871 (20130101) H01F 38/14 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 5/005 (20130101) H02J 7/025 (20130101) Original (OR) Class H02J 7/0042 (20130101) H02J 7/0054 (20130101) H02J 17/00 (20130101) H02J 50/00 (20160201) H02J 50/10 (20160201) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7005 (20130101) Y02T 10/7072 (20130101) Y02T 90/12 (20130101) Y02T 90/14 (20130101) Y02T 90/121 (20130101) Y02T 90/122 (20130101) Y02T 90/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497204 | Symons et al. |
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FUNDED BY |
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APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Christopher T. Symons (Oak Ridge, Tennessee); Justin M. Beaver (Oak Ridge, Tennessee); Rob Gillen (Oak Ridge, Tennessee); Thomas E. Potok (Oak Ridge, Tennessee) |
ABSTRACT | A computer implemented method detects intrusions using a computer by analyzing network traffic. The method includes a semi-supervised learning module connected to a network node. The learning module uses labeled and unlabeled data to train a semi-supervised machine learning sensor. The method records events that include a feature set made up of unauthorized intrusions and benign computer requests. The method identifies at least some of the benign computer requests that occur during the recording of the events while treating the remainder of the data as unlabeled. The method trains the semi-supervised learning module at the network node in-situ, such that the semi-supervised learning modules may identify malicious traffic without relying on specific rules, signatures, or anomaly detection. |
FILED | Monday, August 25, 2014 |
APPL NO | 14/468000 |
ART UNIT | 2435 — Cryptography and Security |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) G06N 99/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class H04L 63/1441 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 09491946 | Santra et al. |
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FUNDED BY |
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APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
INVENTOR(S) | Swadeshmukul Santra (Orlando, Florida); Roseline Menezes (Newark, New Jersey) |
ABSTRACT | Embodiments of the present disclosure, in one aspect, relate to compositions including a silver/silica nanocomposite, methods of making a silver/silica nanocomposite, methods of using a silver/silica nanocomposite, and the like. |
FILED | Wednesday, October 31, 2012 |
APPL NO | 13/664460 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 25/04 (20130101) A01N 59/16 (20130101) Original (OR) Class A01N 59/16 (20130101) A01N 59/20 (20130101) A01N 59/20 (20130101) A01N 59/20 (20130101) A01N 2300/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492428 | Hammond et al. |
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FUNDED BY |
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APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky); Cayetano Heredia University (S.M.P. Lima, Peru) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Gerald B. Hammond (Shelbyville, Kentucky); Zhuang Jin (West Palm Beach, Florida); Paula J. Bates (Louisville, Kentucky); Elsa Merit Reyes-Reyes (Prospect, Kentucky); Abraham Vaisberg (Lima, Peru) |
ABSTRACT | Certain embodiments of the invention include compositions comprising a compound of Formula (I), and salts, isomers, and derivatives thereof. Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I), and salts, isomers, and derivatives thereof. Other embodiments of this invention include methods for treating disease (e.g., cancer) and methods for administering a compound of Formula (I), and salts, isomers, and derivatives thereof. |
FILED | Friday, November 16, 2012 |
APPL NO | 14/358731 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/366 (20130101) Original (OR) Class A61K 36/81 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492477 | Yang |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Jian Yang (State College, Pennsylvania) |
ABSTRACT | In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises promoting cell differentiation or phenotype progression in a population of bone cells by providing a citrate-presenting composition to the population of bone cells. In some embodiments, the citrate-presenting composition is provided to the bone cells at a first stage of cell development selected to obtain a first cell differentiation or phenotype progression. Additionally, in some cases, a second citrate-presenting composition is further provided to the bone cells at a second stage of cell development selected to obtain a second cell differentiation or phenotype progression. |
FILED | Thursday, January 02, 2014 |
APPL NO | 14/146272 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/765 (20130101) A61K 31/785 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/12 (20130101) C08G 63/914 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0669 (20130101) C12N 2500/34 (20130101) C12N 2501/155 (20130101) C12N 2533/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492554 | Arya et al. |
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FUNDED BY |
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APPLICANT(S) | Clemson University Research Foundation (CURF) (Anderson, South Carolina) |
ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
INVENTOR(S) | Dev P. Arya (Greenville, South Carolina); Nihar Ranjan (Clemson, South Carolina); Sunil Kumar (Clemson, South Carolina) |
ABSTRACT | Disclosed herein are compounds, compositions and methods related to viral inhibition. In some forms, the compounds, compositions and methods are related to binding RNA. |
FILED | Monday, May 04, 2015 |
APPL NO | 14/703549 |
ART UNIT | 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48061 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492781 | Galbraith et al. |
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FUNDED BY |
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APPLICANT(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
ASSIGNEE(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
INVENTOR(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
ABSTRACT | Lightweight, small, portable devices and methods are disclosed that provide oxygen-enriched air using an ultra rapid adsorption cycle based on advanced molecular sieve materials. |
FILED | Friday, October 17, 2014 |
APPL NO | 14/516919 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 2/54 (20130101) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/22 (20130101) A61L 9/14 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/10 (20130101) A61M 16/101 (20140204) A61M 35/00 (20130101) A61M 2205/8206 (20130101) A61M 2205/8237 (20130101) A61M 2205/8262 (20130101) A61M 2209/086 (20130101) Separation B01D 53/047 (20130101) Original (OR) Class B01D 53/053 (20130101) B01D 53/0446 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2253/116 (20130101) B01D 2256/12 (20130101) B01D 2257/40 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/78 (20130101) Pipe-line Systems; Pipe-lines F17D 3/01 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493089 | Shin et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents Of The University Of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Kang G. Shin (Ann Arbor, Michigan); Eugene Kim (Ann Arbor, Michigan) |
ABSTRACT | An efficient way of predicting the power requirements of electric vehicles is proposed based on a history of vehicle power consumption, speed and acceleration as well as road information. By using this information and the operator's driving pattern, a model extracts the vehicles history of speed and acceleration, which in turn enables the prediction of the vehicle's future power requirements. That is, the power requirement prediction is achieved by combining a real-time power requirement model and the estimation of vehicle's acceleration and speed. |
FILED | Tuesday, March 24, 2015 |
APPL NO | 14/666369 |
ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 3/12 (20130101) B60L 11/1851 (20130101) Original (OR) Class B60L 15/2045 (20130101) B60L 2240/12 (20130101) B60L 2240/14 (20130101) B60L 2240/642 (20130101) B60L 2260/44 (20130101) B60L 2260/54 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) H01M 2220/20 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/00 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/72 (20130101) Y02T 10/645 (20130101) Y02T 10/705 (20130101) Y02T 10/7005 (20130101) Y02T 10/7283 (20130101) Y02T 10/7291 (20130101) Y02T 90/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493467 | Knight et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Zachary A. Knight (San Francisco, California); Olusegun Williams (San Francisco, California); Kevan M. Shokat (San Francisco, California) |
ABSTRACT | The present invention provides novel PI3-Kinase antagonists having the formula: and methods of use thereof. |
FILED | Friday, October 18, 2013 |
APPL NO | 14/057899 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493513 | Mehmet et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
ASSIGNEE(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
INVENTOR(S) | Sarikaya Mehmet (Seattle, Washington); Yuhei Hayamizu (Seattle, Washington); Christopher R. So (Palo Alto, California); Candan Tamerler-Behar (Seattle, Washington) |
ABSTRACT | The present invention provides polypeptides that bind to inorganic solid surfaces, structures comprising such polypeptides, and methods of making such structures. |
FILED | Wednesday, October 24, 2012 |
APPL NO | 14/349634 |
ART UNIT | 1676 — Organic Chemistry |
CURRENT CPC | Peptides C07K 7/08 (20130101) C07K 14/001 (20130101) Original (OR) Class C07K 17/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493643 | Li |
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FUNDED BY |
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APPLICANT(S) | Guoqiang Li (Baton Rouge, Louisiana) |
ASSIGNEE(S) | Board of Supervisors of Louisiana State University And Agricultural and Mechanical College (Baton Rouge, Louisiana) |
INVENTOR(S) | Guoqiang Li (Baton Rouge, Louisiana) |
ABSTRACT | A composition comprising thermoset shape memory polymer and a composition for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a close-then-heal mechanism. In use the shape memory polymer serves to bring opposing surfaces in a structural defect into proximity, whereafter heating the molecular scale healing composition to a level at or above its melting point allows for molecular scale healing. The composition has the ability to close macroscopic defects, and to do so repeatedly even if another wound occurs in a previously healed area. |
FILED | Friday, May 04, 2012 |
APPL NO | 13/464062 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/40 (20130101) Compositions of Macromolecular Compounds C08L 25/08 (20130101) Original (OR) Class C08L 25/08 (20130101) C08L 67/02 (20130101) C08L 2201/12 (20130101) C08L 2203/02 (20130101) C08L 2205/16 (20130101) C08L 2312/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493805 | Reardon et al. |
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FUNDED BY |
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APPLICANT(S) | Kenneth F. Reardon (Fort Collins, Colorado); David S. Dandy (Fort Collins, Colorado); Michael Fritzsche (Burgdorf, Germany); Thomas K. Wood (College Station, Texas) |
ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
INVENTOR(S) | Kenneth F. Reardon (Fort Collins, Colorado); David S. Dandy (Fort Collins, Colorado); Michael Fritzsche (Burgdorf, Germany); Thomas K. Wood (College Station, Texas) |
ABSTRACT | Enzymatic biosensors and methods of producing distal tips for biosensor transducers for use in detecting one or more analytes selected from organic compounds susceptible to dehalogenation, organic compounds susceptible to oxygenation and organophosphate compounds susceptible to hydrolysis are disclosed herein, as well as biosensor arrays, methods of detecting and quantifying analytes within a mixture, and devices and methods for delivering reagents to enzymes disposed within the distal tip of a biosensor. |
FILED | Wednesday, April 09, 2008 |
APPL NO | 12/100308 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/002 (20130101) Original (OR) Class C12Q 1/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/914 (20130101) G01N 2333/988 (20130101) G01N 2333/90241 (20130101) G01N 2333/90245 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493806 | Reardon |
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FUNDED BY |
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APPLICANT(S) | Kenneth F. Reardon (Fort Collins, Colorado) |
ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
INVENTOR(S) | Kenneth F. Reardon (Fort Collins, Colorado) |
ABSTRACT | Biosensors and methods of producing biosensors for use in detecting one or more analytes in a solution are disclosed herein. |
FILED | Tuesday, July 31, 2012 |
APPL NO | 13/562592 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/002 (20130101) C12Q 1/005 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/914 (20130101) G01N 2333/988 (20130101) G01N 2333/90241 (20130101) G01N 2333/90245 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493826 | Ismagilov et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California); University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); UNIVERSITY OF CHICAGO (Chicago, Illinois) |
INVENTOR(S) | Rustem F. Ismagilov (Altadena, California); Feng Shen (Pasadena, California); Jason E. Kreutz (Marysville, Washington); Wenbin Du (Wenzhou, China PRC); Bing Sun (Pasadena, California) |
ABSTRACT | Provided are devices comprising multivolume analysis regions, the devices being capable of supporting amplification, detection, and other processes. Also provided are related methods of detecting or estimating the presence nucleic acids, viral levels, and other biological markers of interest. |
FILED | Monday, February 10, 2014 |
APPL NO | 14/177190 |
ART UNIT | 1799 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0094 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/50851 (20130101) B01L 3/502738 (20130101) B01L 2200/027 (20130101) B01L 2200/0605 (20130101) B01L 2200/0642 (20130101) B01L 2300/045 (20130101) B01L 2300/049 (20130101) B01L 2300/0803 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2400/065 (20130101) B01L 2400/0406 (20130101) B01L 2400/0644 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 2531/119 (20130101) C12Q 2537/149 (20130101) C12Q 2563/159 (20130101) C12Q 2565/629 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493887 | Kolis et al. |
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FUNDED BY |
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APPLICANT(S) | Clemson University (Clemson, South Carolina) |
ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
INVENTOR(S) | Joseph W. Kolis (Central, South Carolina); Colin D. McMillen (Liberty, South Carolina); J. Matthew Mann (Anderson, South Carolina) |
ABSTRACT | Disclosed are heterogeneous crystals for use in a laser cavity and methods of forming the crystals. A crystal can be a monolithic crystal containing a vanadate-based activator region and a vanadate-based Q-switch. Disclosed methods include hydrothermal growth techniques for the growth of differing layers on a host. A YVO4 host material can be doped in one region with a suitable active lasing ion and can be formed with another region that is doped with a saturable absorber. Regions can be formed with controlled thickness. Following formation, a heterogeneous crystal can be cut, polished and coated with mirror films at each end for use in a laser cavity to provide short pulses of high power emissions using high frequency pulse modes. |
FILED | Friday, September 26, 2014 |
APPL NO | 14/497949 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/00 (20130101) C30B 7/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494505 | Dennin et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Michael Dennin (Irvine, California); Thomas Boatwright (Fremont, California); Alexander Levine (Los Angeles, California); Arthur A. Evans (Culver City, California); Roy Shlomovitz (Afula, Israel) |
ABSTRACT | The disclosure provides non-contact microrheological methods that can measure the fluctuation of a particle in a monolayer, where the particle is hydrodynamically coupled to the monolayer. The disclosure further comprises devices to carry out the non-contact microrheological methods thereof, including Laser Tweezer devices which can study in vitro biological processes. |
FILED | Tuesday, October 29, 2013 |
APPL NO | 14/065755 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/00 (20130101) Original (OR) Class G01N 13/00 (20130101) G01N 2203/005 (20130101) G01N 2203/0089 (20130101) G01N 2203/0286 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495139 | Stitt et al. |
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FUNDED BY |
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APPLICANT(S) | Gregory Michael Stitt (Gainesville, Florida); John Robert Wernsing (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
INVENTOR(S) | Gregory Michael Stitt (Gainesville, Florida); John Robert Wernsing (Gainesville, Florida) |
ABSTRACT | Elastic computing is an optimization framework that combines standard application code with specialized elastic functions and corresponding optimization tools. The elastic functions provide a knowledge-base of implementation alternatives and parallelization strategies for a given function. When an application calls an elastic function, the elastic computing tools analyze available devices and resources (e.g., cores, GPUs, FPGAs, etc.) and current run-time parameters, and then transparently select from numerous pre-analyzed implementation possibilities to optimize for performance, power, energy, size, or any combination of these goals. |
FILED | Wednesday, April 11, 2012 |
APPL NO | 13/981164 |
ART UNIT | 2196 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 8/4441 (20130101) Original (OR) Class G06F 9/505 (20130101) G06F 9/4425 (20130101) G06F 9/5027 (20130101) G06F 9/5094 (20130101) G06F 11/3452 (20130101) G06F 17/17 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/142 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495378 | Sundaram et al. |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Vinaitheerthan Sundaram (West Lafayette, Indiana); Patrick Eugster (West Lafayette, Indiana); Xiangyu Zhang (West Lafayette, Indiana) |
ABSTRACT | A packet of data and a packet-identification value are transmitted to a network device having an identifier. The stored packet-identification value and the identifier are recorded. The stored packet-identification value is then increased and the process repeats. To receive data, an expected identification value is stored in association with the identifier. A packet and a packet-identification value are received from the network device. The identifier and an indication of receipt are stored. If the received value does not match the expected value for the identifier, the received value is stored. If the values match, the stored packet-identification value and identifier are recorded. If the received value exceeds the expected value, the stored packet-identification value, the identifier and the received identifier are recorded. Subsequently, the stored expected value is increased. The process repeats. Network devices and systems are described. |
FILED | Wednesday, August 27, 2014 |
APPL NO | 14/470112 |
ART UNIT | 2471 — Multiplex and VoIP |
CURRENT CPC | Electric Digital Data Processing G06F 11/3636 (20130101) G06F 17/30153 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 43/062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495761 | Gauglitz et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Steffen Gauglitz (Falmouth, Massachusetts); Christopher Michael Sweeney (Santa Barbara, California); Jonathan Daniel Ventura (Colorado Springs, Colorado); Matthew Alan Turk (Santa Barbara, California); Tobias Höllerer (Santa Barbara, California) |
ABSTRACT | Various embodiments each include at least one of systems, methods, devices, and software for environment mapping with automatic motion model selection. One embodiment in the form of a method includes receiving a video frame captured by a camera device into memory and estimating a type of motion from a previously received video frame held in memory to the received video frame. When the type of motion is the same as motion type of a current keyframe group held in memory, the method includes adding the received video frame to the current keyframe group. Conversely, when the type of motion is not the same motion type of the current keyframe group held in memory, the method includes creating a new keyframe group in memory and adding the received video frame to the new keyframe group. |
FILED | Monday, November 03, 2014 |
APPL NO | 14/531608 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0071 (20130101) G06T 7/2033 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496094 | Macdonald et al. |
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FUNDED BY |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | VANDERBILT UNIVERSITY CENTER FOR TECHNOLOGY TRANSFER AND COMMERCIALIZATION (Nashville, Tennessee) |
INVENTOR(S) | Janet Macdonald (Nashville, Tennessee); Shane Thomas Finn (Nashville, Tennessee) |
ABSTRACT | Embodiments of the present disclosure provide for electrodes, devices including electrodes, methods of making electrodes, and the like. In an embodiment, the electrode includes MoS2, in particular, MoS2 nanostructures (e.g., MoS2 nano-petals). Embodiments of the present disclosure can be used in lithium ion batteries, quantum dot sensitized solar cells, dye sensitized solar cells, thin film photovoltaics, and the like. |
FILED | Monday, February 24, 2014 |
APPL NO | 14/187371 |
ART UNIT | 1755 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2018 (20130101) H01G 9/2022 (20130101) Original (OR) Class H01G 9/2031 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/542 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/813 (20130101) Y10S 977/896 (20130101) Y10S 977/948 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496229 | Rogers et al. |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | John A. Rogers (Champaign, Illinois); Seung-Kyun Kang (Urbana, Illinois); SukWon Hwang (Urbana, Illinois); Jianjun Cheng (Champaign, Illinois); Yanfeng Zhang (Urbana, Illinois); Hanze Ying (Champaign, Illinois) |
ABSTRACT | The invention provides transient devices, including active and passive devices that physically, chemically and/or electrically transform upon application of at least one internal and/or external stimulus. Incorporation of degradable device components, degradable substrates and/or degradable encapsulating materials each having a programmable, controllable and/or selectable degradation rate provides a means of transforming the device. In some embodiments, for example, transient devices of the invention combine degradable high performance single crystalline inorganic materials with selectively removable substrates and/or encapsulants. |
FILED | Friday, April 11, 2014 |
APPL NO | 14/250671 |
ART UNIT | 2899 — Semiconductors/Memory |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/686 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/44 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0775 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/70 (20130101) H01L 23/06 (20130101) H01L 23/57 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0275 (20130101) H05K 1/0286 (20130101) H05K 1/0306 (20130101) H05K 3/22 (20130101) H05K 3/285 (20130101) H05K 3/287 (20130101) H05K 3/288 (20130101) H05K 5/069 (20130101) H05K 13/0023 (20130101) H05K 2201/10151 (20130101) H05K 2201/10196 (20130101) H05K 2201/10212 (20130101) H05K 2203/175 (20130101) H05K 2203/178 (20130101) H05K 2203/0271 (20130101) H05K 2203/0292 (20130101) H05K 2203/0769 (20130101) H05K 2203/0776 (20130101) H05K 2203/0786 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49124 (20150115) Y10T 137/0318 (20150401) Y10T 428/239 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497134 | Chen |
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FUNDED BY |
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APPLICANT(S) | Yuhua Chen (Houston, Texas) |
ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
INVENTOR(S) | Yuhua Chen (Houston, Texas) |
ABSTRACT | A Wavelength Division Multiplexing (WDM) multi-mode switching system and method and method provides concurrent switching in various switching modes including, but not limited to, an electronic packet switching (EPS) mode, optical circuit switching (OCS) mode, and optical burst switching (OBS) mode. Edge routers in the WDM multi-mode switching systems may provide a traffic management module that processes incoming data and routes the data for transmission in an electronic packet switching (EPS), optical burst switching (OBS), or optical circuit switching (OCS) modes via a WDM link. |
FILED | Monday, July 06, 2015 |
APPL NO | 14/791679 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Multiplex Communication H04J 14/0221 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/625 (20130101) Original (OR) Class H04L 47/626 (20130101) Selecting H04Q 11/0066 (20130101) H04Q 2011/0016 (20130101) H04Q 2011/0064 (20130101) H04Q 2011/0092 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497381 | Kim |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Nam Sung Kim (Middleton, Wisconsin) |
ABSTRACT | A signal processing circuit, for example, an image signal processor, is operated in two modes including a first mode for providing output optimized for human perception and a second mode providing output optimized for feature detection where the image signal processor in the second mode provides a degraded output with respect to human perception that nevertheless saves power and provides reliable feature detection. |
FILED | Wednesday, January 14, 2015 |
APPL NO | 14/596565 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Pictorial Communication, e.g Television H04N 5/23241 (20130101) Original (OR) Class H04N 5/23245 (20130101) H04N 5/23293 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497855 | Sirman et al. |
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FUNDED BY |
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APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Asli Sirman (Boston, Massachusetts); Ahmed Busnaina (Needham, Massachusetts); Cihan Yilmaz (Boston, Massachusetts); Jun Huang (Malden, Massachusetts); Sivasubramanian Somu (Natick, Massachusetts) |
ABSTRACT | A method for high rate assembly of nanoelements into two-dimensional void patterns on a non-conductive substrate surface utilizes an applied electric field to stabilize against forces resulting from pulling the substrate through the surface of a nanoelement suspension. The electric field contours emanating from a conductive layer in the substrate, covered by an insulating layer, are modified by a patterned photoresist layer, resulting in an increased driving force for nanoelements to migrate from a liquid suspension to voids on a patterned substrate having a non-conductive surface. The method can be used for the production of microscale and nanoscale circuits, sensors, and other electronic devices. |
FILED | Friday, August 28, 2015 |
APPL NO | 14/838930 |
ART UNIT | 2847 — Electrical Circuits and Systems |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/04 (20130101) C25D 13/12 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0243 (20130101) H01L 21/0259 (20130101) H01L 21/02628 (20130101) H01L 29/0665 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) H05K 1/0213 (20130101) H05K 1/0306 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 09491916 | Steber et al. |
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FUNDED BY |
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APPLICANT(S) | Camille Marie Steber (Pullman, Washington); Kimberlee Kae Kidwell (Pullman, Washington); Victor Louis Demacon (Pullman, Washington); Patricia Ann Okubara (Pullman, Washington) |
ASSIGNEE(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington); UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
INVENTOR(S) | Camille Marie Steber (Pullman, Washington); Kimberlee Kae Kidwell (Pullman, Washington); Victor Louis Demacon (Pullman, Washington); Patricia Ann Okubara (Pullman, Washington) |
ABSTRACT | Particular aspects provide novel mutant plants and plant parts thereof, derived via mutagenesis, having disease resistance and other useful traits. Particular embodiments provide a wheat genotype ‘RRR Scarlet’ (‘Scarlet-Rz1’), plants and seeds thereof, methods for producing a plant comprising crossing ‘Scarlet-Rz1’ plants with another wheat plant, hybrid wheat seeds and plants produced by crossing ‘Scarlet-Rz1’ plants with another line or plant, and creation of variants by mutagenesis or transformation of ‘Scarlet-Rz1’. Additional aspects provide methods for producing other varieties or breeding lines derived from ‘Scarlet-Rz1’ and to varieties or breeding lines produced thereby. Further aspects provide for mutant plants and plant parts thereof that are resistant and/or tolerant to plant root fungal pathogens such as Rhizoctonia and Pythium. Additional embodiments provide mutant plants and plant parts thereof that exhibit stress tolerance and/or resistance. Yet further aspects provide mutant plants and plant parts thereof that are drought resistant or tolerant. |
FILED | Wednesday, February 07, 2007 |
APPL NO | 12/278563 |
ART UNIT | 1662 — Plants |
CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) A01H 1/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492500 | Call et al. |
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FUNDED BY |
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APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
ASSIGNEE(S) | Washington State University (Pullman, Washington) |
INVENTOR(S) | Douglas R. Call (Pullman, Washington); Lauren Eberhart (Pullman, Washington); Kelly A. Brayton (Pullman, Washington); Thomas E. Besser (Pullman, Washington); Ashish Sawant (Pullman, Washington); Lisa Orfe (Pullman, Washington) |
ABSTRACT | Microcin MccPDI and bacteria harboring the mcpM gene which encodes MccPDI, limit growth of and/or kill pathogenic bacteria such as pathogenic Escherichia coli (E. coli) and/or Shigella bacteria via proximity-dependent inhibition (PDl). |
FILED | Friday, June 14, 2013 |
APPL NO | 14/407975 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) A01N 63/02 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 38/164 (20130101) Original (OR) Class Peptides C07K 14/245 (20130101) Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 3/381 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10021 (20130101) C12N 2710/14021 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492521 | Liles et al. |
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FUNDED BY |
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APPLICANT(S) | Auburn Univeristy (Auburn, Alabama) |
ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
INVENTOR(S) | Mark R. Liles (Auburn, Alabama); Jeffery S. Terhune (Auburn, Alabama); Joseph C. Newton (Auburn, Alabama); Mohammad J. Hossain (Auburn, Alabama); Dawei Sun (Auburn, Alabama); Charles Thurlow (Auburn, Alabama) |
ABSTRACT | Disclosed are attenuated bacteria, compositions comprising attenuated bacteria, and vectors and methods for preparing attenuated bacteria. The attenuated bacteria may include attenuated Aeromonas hydrophila for use in vaccinating aquatic animals such as channel catfish against Motile Aeromonas Septicemia (MAS). |
FILED | Thursday, May 28, 2015 |
APPL NO | 14/724388 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/02 (20130101) A61K 39/0208 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/55 (20130101) A61K 2039/521 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/545 (20130101) A61K 2039/552 (20130101) Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492530 | Olsen et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Christopher W. Olsen (Madison, Wisconsin); Gabriele A. Landolt (Fort Collins, Colorado); Alexander I. Karasin (Madison, Wisconsin) |
ABSTRACT | The invention provides an isolated H3 equine influenza A virus, as well as methods of preparing and using the virus, and genes or proteins thereof. |
FILED | Monday, August 31, 2015 |
APPL NO | 14/840759 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/525 (20130101) A61K 2039/552 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16121 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/91 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/11 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493846 | Ding et al. |
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FUNDED BY |
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APPLICANT(S) | Shou-Wei Ding (Riverside, California); Qingfa Wu (Riverside, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Shou-Wei Ding (Riverside, California); Qingfa Wu (Riverside, California) |
ABSTRACT | In one embodiment, the disclosure provides methods and systems for identifying viral nucleic acids in a sample. In another embodiment the invention provides methods for viral genome assembly and viral discovery using small inhibitory RNAs, or “small silencing,” RNAs (siRNAS), micro-RNAs (miRNAs) and/or PIWI-interacting RNAs (piRNAs), including siRNAS, miRNAs and/or piRNAs isolated or sequenced from invertebrate organisms such as insects (Anthropoda), nematodes (Nemapoda), Mollusca, Porifera, and other invertebrates, and/or plants, fungi or algae, Cyanobacteria and the like. |
FILED | Tuesday, June 01, 2010 |
APPL NO | 13/375467 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Original (OR) Class C12Q 2600/178 (20130101) Electric Digital Data Processing G06F 19/14 (20130101) G06F 19/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493882 | Bhavaraju et al. |
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FUNDED BY |
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APPLICANT(S) | Ceramatec, Inc. (Salt Lake City, Utah) |
ASSIGNEE(S) | CERAMATEC, INC. (Salt Lake City, Utah) |
INVENTOR(S) | Sai Bhavaraju (West Jordan, Utah); James Mosby (Salt Lake City, Utah); Patrick McGuire (Salt Lake City, Utah); Mukund Karanjikar (West Valley City, Utah); Daniel Taggart (Salt Lake City, Utah); Jacob Staley (West Jordan, Utah) |
ABSTRACT | Methods, equipment, and reagents for preparing organic compounds using custom electrolytes based on different ionic liquids in electrolytic decarboxylation reactions are disclosed. |
FILED | Wednesday, March 12, 2014 |
APPL NO | 14/206981 |
ART UNIT | 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 1/2078 (20130101) C07C 29/32 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/00 (20130101) C10G 2300/44 (20130101) C10G 2300/1011 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/00 (20130101) Original (OR) Class C25B 3/10 (20130101) C25B 9/08 (20130101) C25B 15/08 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP27392 | Hanna et al. |
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FUNDED BY |
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APPLICANT(S) | Wayne W. Hanna (Chula, Georgia); Brian M. Schwartz (Tifton, Georgia) |
ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Wayne W. Hanna (Chula, Georgia); Brian M. Schwartz (Tifton, Georgia) |
ABSTRACT | Bermudagrass ‘DT-1’ is provided. The new and distinct upright variety has excellent drought tolerance, superior wear tolerance, small seed heads, and thrives in hot and humid conditions. The asexually reproduced triploid variety is reliably propagated vegetatively. |
FILED | Wednesday, June 10, 2015 |
APPL NO | 14/545732 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/389 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP27393 | Chandra et al. |
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FUNDED BY |
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APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
INVENTOR(S) | Ambika Chandra (Dallas, Texas); Anthony D. Genovesi (Dallas, Texas); Milton C. Engelke (College Station, Texas) |
ABSTRACT | ‘DALSA 0605’ is a new variety of St. Augustinegrass distinguished by having high tolerance to grey leaf spot disease, significantly reduced levels of fecundity and juvenile development of Southern chinch bugs, and superior drought resistance conferred through a combination of tolerance to drying soil, deep genetic rooting potential, and rapid recovery following drought, as disclosed herein. |
FILED | Friday, January 16, 2015 |
APPL NO | 14/544540 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/392 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 09493635 | Wise et al. |
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FUNDED BY |
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APPLICANT(S) | Kristopher Eric Wise (Hampton, Virginia); Cheol Park (Yorktown, Virginia); Jin Ho Kang (Yorktown, Virginia); Emilie J. Siochi (Newport News, Virginia); Joycelyn S. Harrison (Hampton, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Kristopher Eric Wise (Hampton, Virginia); Cheol Park (Yorktown, Virginia); Jin Ho Kang (Yorktown, Virginia); Emilie J. Siochi (Newport News, Virginia); Joycelyn S. Harrison (Hampton, Virginia) |
ABSTRACT | Stable dispersions of carbon nanotubes (CNTs) in polymeric matrices include CNTs dispersed in a host polymer or copolymer whose monomers have delocalized electron orbitals, so that a dispersion interaction results between the host polymer or copolymer and the CNTs dispersed therein. Nanocomposite products, which are presented in bulk, or when fabricated as a film, fiber, foam, coating, adhesive, paste, or molding, are prepared by standard means from the present stable dispersions of CNTs in polymeric matrices, employing dispersion interactions, as presented hereinabove. |
FILED | Friday, December 22, 2006 |
APPL NO | 11/644019 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/24 (20130101) Original (OR) Class C08K 2201/011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493643 | Li |
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FUNDED BY |
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APPLICANT(S) | Guoqiang Li (Baton Rouge, Louisiana) |
ASSIGNEE(S) | Board of Supervisors of Louisiana State University And Agricultural and Mechanical College (Baton Rouge, Louisiana) |
INVENTOR(S) | Guoqiang Li (Baton Rouge, Louisiana) |
ABSTRACT | A composition comprising thermoset shape memory polymer and a composition for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a close-then-heal mechanism. In use the shape memory polymer serves to bring opposing surfaces in a structural defect into proximity, whereafter heating the molecular scale healing composition to a level at or above its melting point allows for molecular scale healing. The composition has the ability to close macroscopic defects, and to do so repeatedly even if another wound occurs in a previously healed area. |
FILED | Friday, May 04, 2012 |
APPL NO | 13/464062 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/40 (20130101) Compositions of Macromolecular Compounds C08L 25/08 (20130101) Original (OR) Class C08L 25/08 (20130101) C08L 67/02 (20130101) C08L 2201/12 (20130101) C08L 2203/02 (20130101) C08L 2205/16 (20130101) C08L 2312/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494044 | Kloesel |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Kurt J Kloesel (Wrightwood, California) |
ABSTRACT | The present invention is a turbojet design that integrates power generation into the turbojet itself, rather than use separate generators attached to the turbojet for power generation. By integrating the power generation within the jet engine, the weight of the overall system is significantly reduced, increasing system efficiency. Also, by integrating the power generating elements of the system within the air flow of the jet engine, the present invention can use the heat generated by the power generating elements (which is simply expelled waste heat in current designs) to increase the engine performance. |
FILED | Wednesday, April 02, 2014 |
APPL NO | 14/243576 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 15/10 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/36 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494143 | Patterson |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Michael J. Patterson (Brunswick, Ohio) |
ABSTRACT | Ion optics for use in a conventional or annular or other shaped ion thruster are disclosed including a plurality of planar, spaced apart ion optic electrode pairs sized to include a diameter smaller than the diameter of thruster exhaust and retained in, on or otherwise associated with a frame across the thruster exhaust. An electrical connection may be provided for establishing electrical connectivity among a set of first upstream electrodes and an electrical connection may be provided for establishing electrical connectivity among the second downstream electrodes. |
FILED | Friday, January 10, 2014 |
APPL NO | 14/152125 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/405 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0037 (20130101) Original (OR) Class F03H 1/0043 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 27/024 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09497846 | Szatkowski et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | George N. Szatkowski (Charlottesville, Virginia); Kenneth L. Dudley (Newport News, Virginia); Larry A. Ticatch (Yorktown, Virginia); Laura J. Smith (Yorktown, Virginia); Sandra V. Koppen (Suffolk, Virginia); Truong X. Nguyen (Hampton, Virginia); Jay J. Ely (Yorktown, Virginia) |
ABSTRACT | A plasma generator includes a pair of identical spiraled electrical conductors separated by dielectric material. Both spiraled conductors have inductance and capacitance wherein, in the presence of a time-varying electromagnetic field, the spiraled conductors resonate to generate a harmonic electromagnetic field response. The spiraled conductors lie in parallel planes and partially overlap one another in a direction perpendicular to the parallel planes. The geometric centers of the spiraled conductors define endpoints of a line that is non-perpendicular with respect to the parallel planes. A voltage source coupled across the spiraled conductors applies a voltage sufficient to generate a plasma in at least a portion of the dielectric material. |
FILED | Wednesday, October 22, 2014 |
APPL NO | 14/520679 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) Original (OR) Class H05H 1/2406 (20130101) H05H 2001/2412 (20130101) H05H 2001/2456 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 09492571 | Gray et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts Medical School (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Brian D. Gray (Malvern, Pennsylvania); Mary Rusckowski (Southborough, Massachusetts); Koon Y. Pak (Malvern, Pennsylvania) |
ABSTRACT | The invention relates to novel multi-modality probes for imaging, tracking and analyzing stem cells and related biological samples, and methods of preparation and use thereof. The molecular probes of the invention are constructed, for example, by utilizing (a) the high selectivity of long hydrocarbon chains for binding to plasma membranes of cells, (b) a near-infrared (NIR) dye for optical imaging, and (c) a radionuclide for PET or SPECT imaging. The in vitro and in vivo data of the optical and radiolabeled probes demonstrated their utility for detecting the presence of stem cells with multiple imaging modalities. |
FILED | Monday, May 27, 2013 |
APPL NO | 14/400757 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 51/0446 (20130101) A61K 51/0478 (20130101) A61K 51/0482 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) Heterocyclic Compounds C07D 209/14 (20130101) C07D 209/20 (20130101) C07D 403/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09492781 | Galbraith et al. |
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FUNDED BY |
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APPLICANT(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
ASSIGNEE(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
INVENTOR(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
ABSTRACT | Lightweight, small, portable devices and methods are disclosed that provide oxygen-enriched air using an ultra rapid adsorption cycle based on advanced molecular sieve materials. |
FILED | Friday, October 17, 2014 |
APPL NO | 14/516919 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 2/54 (20130101) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/22 (20130101) A61L 9/14 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/10 (20130101) A61M 16/101 (20140204) A61M 35/00 (20130101) A61M 2205/8206 (20130101) A61M 2205/8237 (20130101) A61M 2205/8262 (20130101) A61M 2209/086 (20130101) Separation B01D 53/047 (20130101) Original (OR) Class B01D 53/053 (20130101) B01D 53/0446 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2253/116 (20130101) B01D 2256/12 (20130101) B01D 2257/40 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/78 (20130101) Pipe-line Systems; Pipe-lines F17D 3/01 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493252 | Tsay et al. |
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FUNDED BY |
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APPLICANT(S) | Busek Co., Inc. (Natick, Massachusetts) |
ASSIGNEE(S) | Busek Co., Inc. (Natick, Massachusetts) |
INVENTOR(S) | Michael M. Tsay (North Chelmsford, Massachusetts); Vladimir J. Hruby (Waban, Massachusetts); Christopher M. Grenier (Dudley, Massachusetts); William P. Costa (Norfolk, Massachusetts); Derek J. Lafko (Holliston, Massachusetts) |
ABSTRACT | A thruster includes a reactor including bundled metal elongate members therein configured to disassociate an introduced propellant flowing between the members, a combustor for combusting products of the disassociation, and a nozzle downstream of the combustor. |
FILED | Wednesday, April 23, 2014 |
APPL NO | 14/259468 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/401 (20130101) Original (OR) Class Jet-propulsion Plants F02K 9/68 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493818 | Kazakov et al. |
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FUNDED BY |
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APPLICANT(S) | SomaGenics, Inc. (Santa Cruz, California) |
ASSIGNEE(S) | SOMAGENICS, INC. (Santa Cruz, California) |
INVENTOR(S) | Sergei A. Kazakov (San Jose, California); Pavan Kumar (Arlington, Massachusetts); Brian H. Johnston (Scotts Valley, California) |
ABSTRACT | Currently, the circularization of small RNAs is broadly regarded as an obstacle in ligation-related assays and explicitly avoided while short lengths of linear RNA targets is broadly recognized as a factor limiting use of conventional primers in PCR-related assays. In contrast, the disclosed invention capitalizes on circularization of small RNA targets or their conjugates with oligonucleotide adapters. The circular RNA templates provide amplification of the target sequences via synthesis of multimer nucleic acids that can be either labeled for direct detection or subjected to PCR amplification and detection. Structure of small circular RNAs and corresponding multimeric nucleic acids provide certain advantages over current methods including flexibility in design of conventional RT and PCR primers as well as use of 5′-overlapping dimer-primers for efficient and sequence-specific amplification of short target sequences. Our invention also reduces number of steps and reagents while increasing sensitivity and accuracy of detection of small RNAs with both 2′OH and 2′-OMe at their 3′ ends. Our invention increase sensitivity and specificity of detection of microRNAs and other small RNAs with both 2′OH and 2′-OMe at their 3′ ends while allowing us to distinguish these two forms from each other. |
FILED | Tuesday, August 25, 2015 |
APPL NO | 14/835544 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class C12Q 1/682 (20130101) C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6865 (20130101) C12Q 1/6865 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2525/143 (20130101) C12Q 2525/207 (20130101) C12Q 2525/207 (20130101) C12Q 2525/313 (20130101) C12Q 2531/125 (20130101) C12Q 2531/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09493847 | Huang |
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FUNDED BY |
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APPLICANT(S) | Wei Huang (Foster City, California) |
ASSIGNEE(S) | MONOGRAM BIOSCIENCES, INC. (San Francisco, California) |
INVENTOR(S) | Wei Huang (Foster City, California) |
ABSTRACT | The invention provides a method for determining whether a human immunodeficiency virus is likely to be have enhanced ability to enter a cell expressing CD4 and CXCR4 relative to a reference HIV. In certain aspects, the methods comprise detecting one or more amino acids in an envelope protein of the HIV associated with enhanced ability to enter CD4- and CXCR4-expressing cells and determining that the HIV's ability to enter such cells is enhanced relative to a reference HIV, e.g., an HIV that does not comprise such amino acid(s). |
FILED | Thursday, February 09, 2012 |
APPL NO | 13/370109 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 09494762 | Benner et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Alan F. Benner (Poughkeepsie, New York); Mark A. Brandon (Poughkeepsie, New York); Eric J. McKeever (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York) |
ABSTRACT | Aspects of the present invention include an optical fiber routing mat for routing optical fibers. The optical fiber routing mat includes a first layer of material and a second layer of material. A surface of the first layer of material is adhesively coupled to a surface of the second layer of material. The optical fiber routing mat includes one or more optical fibers disposed between the first layer of material and the second layer of material. The one or more optical fibers are bent to a radius at least large enough to prevent damage to the one or more optical fibers. |
FILED | Wednesday, September 09, 2015 |
APPL NO | 14/849197 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/3608 (20130101) G02B 6/3897 (20130101) G02B 6/4471 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494763 | Benner et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Alan F. Benner (Poughkeepsie, New York); Mark A. Brandon (Poughkeepsie, New York); Eric J. McKeever (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York) |
ABSTRACT | Aspects of the present invention include an optical fiber routing mat for routing optical fibers. The optical fiber routing mat includes a first layer of material and a second layer of material. A surface of the first layer of material is adhesively coupled to a surface of the second layer of material. The optical fiber routing mat includes one or more optical fibers disposed between the first layer of material and the second layer of material. The one or more optical fibers are bent to a radius at least large enough to prevent damage to the one or more optical fibers. |
FILED | Wednesday, February 04, 2015 |
APPL NO | 14/613900 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/3608 (20130101) G02B 6/4478 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09495137 | Coetzee et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Peter L. Coetzee (Chester, United Kingdom); Anton V. Riabov (Ann Arbor, Michigan); Octavian Udrea (Valhalla, New York) |
ABSTRACT | Embodiments include methods, and computer program products of an analytical workflow system. Aspects include: observing analytical workflow patterns of one or more users to gather statistics, predicting an analytical workflow and parameter values likely to be requested in future based on the observations according to a compilation policy, applying a parameter generation policy and preparing the predicted analytical workflows according to the compilation policy, and executing analytical workflows and deploying the executed analytical workflows according to a deployment policy. The aspects also include: refining an analytical workflow specification, reusing prepared, executed or deployed analytical workflows, and terminating one or more prepared, executed or deployed analytical workflows when these analytical workflows are unlikely to be requested by a user in the near future according to a termination policy. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/979677 |
ART UNIT | 2199 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 8/443 (20130101) Original (OR) Class G06F 8/4441 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496194 | Arvelo et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Amilcar R. Arvelo (Poughkeepsie, New York); Michael J. Ellsworth (Poughkeepsie, New York); Eric J. McKeever (Poughkeepsie, New York); Thong N. Nguyen (Poughkeepsie, New York); Edward J. Seminaro (Milton, New York) |
ABSTRACT | A method of forming a custom module lid. The method may include placing a multichip module (MCM) between a module base and a temporary lid, target components are exposed through viewing windows in the temporary lid, a top surface of the target components is measured and mapped to create a target profile, the target profile is used to form custom pockets in a custom lid, and the custom pockets correspond to the target components. |
FILED | Friday, November 07, 2014 |
APPL NO | 14/535391 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/06 (20130101) H01L 23/043 (20130101) Original (OR) Class H01L 23/3675 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 09493849 | Qiao et al. |
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FUNDED BY |
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APPLICANT(S) | Virent, Inc. (Madison, Wisconsin) |
ASSIGNEE(S) | VIRENT, INC. (Madison, Wisconsin) |
INVENTOR(S) | Ming Qiao (Pewaukee, Wisconsin); Randy D. Cortright (Madison, Wisconsin); Dick A. Nagaki (The Woodlands, Texas) |
ABSTRACT | The present invention provides processes for deconstructing biomass using a solvent produced in a bioreforming reaction. |
FILED | Monday, December 14, 2015 |
APPL NO | 14/968299 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 30/12 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/06 (20130101) C10G 1/065 (20130101) C10G 3/42 (20130101) C10G 3/49 (20130101) C10G 2300/44 (20130101) C10G 2300/805 (20130101) C10G 2300/1011 (20130101) C10G 2300/1014 (20130101) Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 13/00 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09496141 | Kazlas et al. |
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FUNDED BY |
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APPLICANT(S) | Peter T. Kazlas (Sudbury, Massachusetts); John Spencer Morris (Dodge City, Kansas); Robert J. Nick (Pepperell, Massachusetts); Zoran Popovic (Mississauga, Canada); Matthew Stevenson (Waltham, Massachusetts); Jonathan S. Steckel (Carlisle, Massachusetts) |
ASSIGNEE(S) | QD VISION, INC. (Lexington, Massachusetts) |
INVENTOR(S) | Peter T. Kazlas (Sudbury, Massachusetts); John Spencer Morris (Dodge City, Kansas); Robert J. Nick (Pepperell, Massachusetts); Zoran Popovic (Mississauga, Canada); Matthew Stevenson (Waltham, Massachusetts); Jonathan S. Steckel (Carlisle, Massachusetts) |
ABSTRACT | A method of making a device comprises forming a layer comprising quantum dots over a substrate including a first electrode, fixing the layer comprising quantum dots formed over the substrate, and exposing at least a portion of, and preferably all, exposed surfaces of the fixed layer comprising quantum dots to small molecules. Also disclosed is a method of making a device, the method comprising forming a layer comprising quantum dots over a substrate including a first electrode, exposing the layer comprising quantum dots to small molecules and light flux. A method of making a film including a layer comprising quantum dots, and a method of preparing a device component including a layer comprising quantum dots are also disclosed. Devices, device components, and films are also disclosed. |
FILED | Thursday, May 10, 2012 |
APPL NO | 13/468199 |
ART UNIT | 2897 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/565 (20130101) C09K 11/883 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0237 (20130101) H01L 21/0256 (20130101) H01L 21/02521 (20130101) H01L 21/02557 (20130101) H01L 21/02601 (20130101) H01L 21/02664 (20130101) Original (OR) Class H01L 29/127 (20130101) H01L 33/06 (20130101) H01L 33/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 09492536 | Offner et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Halina Offner (Portland, Oregon); Patricia D. Hurn (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon); Gregory G. Burrows (Portland, Oregon) |
ABSTRACT | Two-domain MHC polypeptides are useful for modulating activities of antigen-specific T-cells, including for modulating pathogenic potential and effects of antigen-specific T-cells. Exemplary MHC class II-based recombinant T-cell ligands (RTLs) of the invention include covalently linked β1 and α1 domains, and MHC class I-based molecules that comprise covalently linked α1 and α2 domains. These polypeptides may also include covalently linked antigenic determinants, toxic moieties, and/or detectable labels. The disclosed polypeptides can be used to target antigen-specific T-cells, and are useful, among other things, to detect and purify antigen-specific T-cells, to induce or activate T-cells, to modulate T-cell activity, including by regulatory switching of T-cell cytokine and adhesion molecule expression, to treat conditions mediated by antigen-specific T-cells, including treatment and/or prevention of central nervous system damage relating to stroke. |
FILED | Friday, June 05, 2015 |
APPL NO | 14/732145 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/0005 (20130101) A61K 39/385 (20130101) Original (OR) Class A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 2039/605 (20130101) A61K 2039/627 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
US 09494579 | Schwoebel et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Eric D. Schwoebel (Woburn, Massachusetts); James D. Harper (Jamaica Plain, Massachusetts); Martha S. Petrovick (Barre, Massachusetts); Frances E. Nargi (Littleton, Massachusetts); Todd H. Rider (Littleton, Massachusetts); Kristine E. Hogan (Danvers, Massachusetts); Richard H. Mathews (Chelmsford, Massachusetts); Joseph Lacirignola (Beverly, Massachusetts); Mark Hennessy (Morrisville, North Carolina); Trina R. Vian (Groton, Massachusetts); Rose M. Joseph (Westford, Massachusetts); Raymond S. Uttaro (Lexington, Massachusetts); Shaun Berry (Chelmsford, Massachusetts); Bernadette Johnson (Hollis, New Hampshire); Mark A. Hollis (Concord, Massachusetts) |
ABSTRACT | The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples. |
FILED | Tuesday, September 09, 2014 |
APPL NO | 14/481044 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 1/3461 (20130101) C12M 1/3476 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 2563/131 (20130101) C12Q 2565/619 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6454 (20130101) G01N 33/582 (20130101) G01N 33/5304 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 09492508 | Gardella et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas J. Gardella (Needham, Massachusetts); John T. Potts, Jr. (Newton, Massachusetts); Harald Jueppner (Lexington, Massachusetts); Makoto Okazaki (Tokyo, Japan) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Chugai Seiyaku Kabushiki Kaisha (Tokyo, Japan) |
INVENTOR(S) | Thomas J. Gardella (Needham, Massachusetts); John T. Potts, Jr. (Newton, Massachusetts); Harald Jueppner (Lexington, Massachusetts); Makoto Okazaki (Tokyo, Japan) |
ABSTRACT | Disclosed are two PTH analog ligands, SP-PTH-AAK and Aib-SP-PTH-AAK, that have long-acting activity at the PTH receptor, as demonstrated both in vitro and in vivo. These polypeptides are thus particularly useful in the treatment of diseases, such as hypoparathyroidism, in which long-acting activity is desired. The method of making the analog polypeptides is also disclosed. |
FILED | Thursday, May 12, 2011 |
APPL NO | 13/697249 |
ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/29 (20130101) Original (OR) Class Peptides C07K 14/635 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09494083 | Plummer et al. |
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FUNDED BY |
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APPLICANT(S) | Jessica Lynn Plummer (Erie, Pennsylvania); Gail LeRoy Detar (Erie, Pennsylvania); Shashi Kiran (Erie, Pennsylvania); Shridhar Shrikant Kulkarni (Erie, Pennsylvania); Lawrence Heverley, III (Ripley, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Jessica Lynn Plummer (Erie, Pennsylvania); Gail LeRoy Detar (Erie, Pennsylvania); Shashi Kiran (Erie, Pennsylvania); Shridhar Shrikant Kulkarni (Erie, Pennsylvania); Lawrence Heverley, III (Ripley, New York) |
ABSTRACT | Methods and systems are provided related to an emissions control system. The emissions control system has an exhaust after-treatment system defining a plurality of distinct exhaust flow passages through which at least a portion of an exhaust stream can flow, e.g., the exhaust stream is produced by an engine. The emissions control system also includes a controller for controlling injection of reductant into the exhaust stream flowing through each of the flow passages. In one example, the emissions control system is configured for use in a vehicle, such as a locomotive or other rail vehicle. |
FILED | Tuesday, December 21, 2010 |
APPL NO | 13/518122 |
ART UNIT | 3748 — Electrical Circuits and Systems |
CURRENT CPC | Separation B01D 53/9477 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/208 (20130101) F01N 3/0222 (20130101) F01N 3/0256 (20130101) F01N 3/2066 (20130101) F01N 3/2803 (20130101) F01N 9/002 (20130101) F01N 13/002 (20130101) F01N 13/02 (20130101) F01N 13/04 (20130101) F01N 13/08 (20130101) F01N 13/017 (20140603) F01N 13/18 (20130101) F01N 13/0097 (20140603) F01N 13/1805 (20130101) F01N 2590/08 (20130101) F01N 2610/02 (20130101) F01N 2610/03 (20130101) F01N 2610/10 (20130101) F01N 2610/1406 (20130101) F01N 2610/1433 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/16 (20130101) Original (OR) Class Controlling Combustion Engines F02D 41/045 (20130101) F02D 41/083 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/24 (20130101) Y02T 10/47 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 15, 2016.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2016/fedinvent-patents-20161115.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page