FedInvent™ Patents

Patent Details for Tuesday, November 22, 2016

This page was updated on Monday, March 27, 2023 at 04:54 AM GMT

Department of Health and Human Services (HHS)

09497943 — Nucleic acid constructs encoding reprogramming factors linked by self-cleaving peptides

US 09497943	Jaenisch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Rudolf Jaenisch (Brookline, Massachusetts); Bryce Woodbury Carey (New York, New York)
ASSIGNEE(S)	Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S)	Rudolf Jaenisch (Brookline, Massachusetts); Bryce Woodbury Carey (New York, New York)
ABSTRACT	The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially differentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a pluripotent or multipotent state. In further embodiments the invention also relates to reprogrammed somatic cells produced by methods of the invention, to chimeric animals comprising reprogrammed somatic cells of the invention, to uses of said cells, and to methods for identifying agents useful for reprogramming somatic cells.
FILED	Monday, June 15, 2009
APPL NO	12/997815
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0696 (20130101) C12N 15/79 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2501/60 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2506/11 (20130101) C12N 2506/115 (20130101) C12N 2510/00 (20130101) C12N 2740/15041 (20130101) C12N 2740/15043 (20130101) C12N 2740/16043 (20130101) C12N 2799/027 (20130101) C12N 2800/108 (20130101) C12N 2840/203 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101)
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09498121 — Surgical microscopes using optical coherence tomography and related systems

US 09498121	Buckland et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Bioptigen, Inc. (Morrisville, North Carolina)
ASSIGNEE(S)	Bioptigen, Inc. (Morrisville, North Carolina)
INVENTOR(S)	Eric L. Buckland (Hickory, North Carolina); Nestor O. Farmiga (Rochester, New York); Robert H. Hart (Cary, North Carolina); Andrew Murnan (Saratoga Springs, New York); Christopher Saxer (Chapel Hill, North Carolina)
ABSTRACT	Some embodiments of the present inventive concept provide optical coherence tomography (OCT) systems for integration with a microscope. The OCT system includes a sample arm coupled to the imaging path of a microscope. The sample arm includes an input beam zoom assembly including at least two movable lenses configured to provide shape control for an OCT signal beam; a scan assembly including at least one scanning mirror and configured for telecentric scanning of the OCT signal beam; and a beam expander configured to set the OCT signal beam diameter incident on the microscope objective. The shape control includes separable controls for numerical aperture and focal position of the imaged OCT beam.
FILED	Monday, June 22, 2015
APPL NO	14/745980
ART UNIT	2872 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/13 (20130101) A61B 3/102 (20130101) Original (OR) Class A61B 5/0066 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02039 (20130101) G01B 9/02091 (20130101) Optical Elements, Systems, or Apparatus G02B 1/11 (20130101) G02B 21/02 (20130101) G02B 21/0012 (20130101) G02B 21/0048 (20130101) G02B 27/0031 (20130101) G02B 27/141 (20130101) G02B 27/0955 (20130101)
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09498293 — Automated cell patch clamping method and apparatus

US 09498293	Kodandaramaiah et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) NIH Office of the Director (NIHOD) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	Suhasa Bangalore Kodandaramaiah (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Craig Richard Forest (Atlanta, Georgia)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Suhasa Bangalore Kodandaramaiah (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Craig Richard Forest (Atlanta, Georgia)
ABSTRACT	In an automated method for in vivo multiple cell patch clamping, cell patch clamping devices are automatically moved into position and targeted to multiple corresponding cells. Cell contact is determined by analyzing the temporal series of measured resistance levels at the clamping devices as they are moved. The difference between successive resistance levels is computed and compared to a threshold, which must be exceeded for a minimum number of computations before neuron contact is assumed. Pneumatic control methods are used to achieve cell-attached or gigaseal formation and subsequent cell break-in, leading to whole-cell patch clamp formation. An automated robotic system automatically performs patch clamping in vivo, automatically detecting cells according to the methodology by analyzing the temporal sequence of electrode impedance changes. By continuously monitoring the patching process and rapidly executing actions triggered by specific measurements, the robot can rapidly find neurons in the living brain and establish recordings.
FILED	Wednesday, November 13, 2013
APPL NO	14/079630
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0538 (20130101) A61B 5/04001 (20130101) A61B 5/6885 (20130101) A61B 19/2203 (20130101) Original (OR) Class A61B 34/32 (20160201) A61B 2503/40 (20130101)
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09498320 — Biomimetic vascular network and devices using the same

US 09498320	Hoganson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	David M. Hoganson (St. Louis, Missouri); Jeffrey T. Borenstein (Newton, Massachusetts)
ASSIGNEE(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
INVENTOR(S)	David M. Hoganson (St. Louis, Missouri); Jeffrey T. Borenstein (Newton, Massachusetts)
ABSTRACT	The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e). The invention also provides compositions comprising a vascular layer for use in tissue lamina as well as a medical devices having a vascular layer and kits.
FILED	Friday, November 15, 2013
APPL NO	14/081378
ART UNIT	3738 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) Original (OR) Class A61F 2/022 (20130101) A61F 2/062 (20130101) A61F 2002/068 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101)
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09498439 — Prodrug compositions, prodrug nanoparticles, and methods of use thereof

US 09498439	Lanza et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Gregory M. Lanza (St. Louis, Missouri); Dipanjan Pan (St. Louis, Missouri)
ASSIGNEE(S)	WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S)	Gregory M. Lanza (St. Louis, Missouri); Dipanjan Pan (St. Louis, Missouri)
ABSTRACT	Nanoparticles comprising a prodrug and prodrugs linked to phospholipids, wherein the linkages facilitate release of the prodrugs from the nanoparticles to sites within a target cell or cell membrane by fusion of the particle and the cell membrane are disclosed. Also disclosed are methods for producing and using the nanoparticles and their constituents.
FILED	Friday, April 15, 2011
APPL NO	13/641252
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 9/145 (20130101) Original (OR) Class A61K 9/1271 (20130101) A61K 31/336 (20130101) A61K 33/24 (20130101) A61K 41/0071 (20130101) A61K 47/488 (20130101) A61K 47/4813 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101)
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09498470 — Antiviral drugs for treatment of arenavirus infection

US 09498470	Dai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	KINETA FOUR, LLC (Seattle, Washington)
ASSIGNEE(S)	Kineta Four, LLC (Seattle, Washington)
INVENTOR(S)	Dongcheng Dai (Corvallis, Oregon); James R. Burgeson (Albany, Oregon); Sean M. Amberg (Corvallis, Oregon); Dennis E. Hruby (Albany, Oregon)
ABSTRACT	Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever.
FILED	Thursday, February 14, 2013
APPL NO	14/379028
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/437 (20130101) A61K 31/4184 (20130101) A61K 31/4439 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 235/06 (20130101) C07D 401/04 (20130101) C07D 471/04 (20130101)
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09498471 — Use of CDK9 inhibitors to reduce cartilage degradation

US 09498471	Haudenschild et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Dominik Haudenschild (Davis, California); Paul Di Cesare (Manhasset, New York); Jasper Yik (Elk Grove, California); Blaine Christiansen (Woodland, California)
ABSTRACT	The present invention relates to the use of cyclin-dependent kinase 9 (CDK9) inhibitors to reduce, inhibit and/or prevent cartilage degradation. CDK9 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. CDK9 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.
FILED	Friday, October 19, 2012
APPL NO	14/351878
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/453 (20130101) Original (OR) Class A61K 31/713 (20130101)
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09498492 — Compositions including triciribine and taxanes and methods of use thereof

US 09498492	Cheng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	University of South Florida (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Jin Q. Cheng (Tampa, Florida); Said M. Sebti (Tampa, Florida)
ABSTRACT	This application relates to combination therapies including triciribine and related compounds and taxanes and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.
FILED	Wednesday, July 01, 2015
APPL NO	14/789347
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/337 (20130101) A61K 31/7064 (20130101) Original (OR) Class A61K 31/7076 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/912 (20130101)
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09498495 — Methods for in vitro differentiation of TH-17+ cells

US 09498495	Manel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Nicolas Manel (Paris, France); Dan R. Littman (New York, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	Nicolas Manel (Paris, France); Dan R. Littman (New York, New York)
ABSTRACT	The present invention is directed to an in vitro method for promoting differentiation and proliferation of human T helper lymphocytes that express IL17 (Th-IL17+ cells). The instant method may be used to generate a population of human T helper lymphocytes that express IL17 (Th-IL17+ cells) in vitro. Methods for screening to identify agents capable of modulating Th-IL17+ cell differentiation are also encompassed by the present invention. Isolated, pure populations of homogeneous Th-IL17+ cells that do not express cellular markers characteristic of Th1, Th2, or Treg cells are also encompassed herein.
FILED	Tuesday, March 26, 2013
APPL NO	13/850497
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 2039/57 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/15 (20130101) C12N 2501/23 (20130101) C12N 2799/027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101)
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09498509 — TIMP3 as VEGF inhibitor

US 09498509	Anand-Apte
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Bela Anand-Apte (Shaker Heights, Ohio)
ASSIGNEE(S)	The Cleveland Clinic Foundation (Cleveland, Ohio)
INVENTOR(S)	Bela Anand-Apte (Shaker Heights, Ohio)
ABSTRACT	Polypeptides or proteins comprising tissue inhibitor of mettaloproteinases-3 (TIMP3) or variants of TIMP3 can be used to substantially inhibit vascular endothelial growth factor (VEGF) binding to VEGF receptor-2 (VEGFR2/KDR/Flk-1)) without substantially inhibiting VEGF binding to VEGF receptor 1 (VEGFR1/Flt-1).
FILED	Tuesday, January 16, 2007
APPL NO	11/653647
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Original (OR) Class
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09498511 — Methods related to the treatment of neurodegenerative and inflammatory conditions

US 09498511	Hong et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Jau-Shyong Hong (Durham, North Carolina); Liya Qin (Durham, North Carolina); Guorong Li (Chapel Hill, North Carolina); Michelle Block (Holly Springs, North Carolina); Wei Zhang (Dalian, China PRC); Po-See Chen (Taipei, Taiwan); Giia-Shuen Peng (Taipei, Taiwan)
ABSTRACT	The invention includes methods of neuroprotection, inducing release of neurotrophic factors, inhibiting the over-activation of innate immune cells, attenuating the toxin-induced death and/or damage of tissues, reducing inflammation, treating an inflammation-related condition, and inhibiting NADPH oxidase, that includes contacting or administering an effective amount of at least one compound of the invention that include: valproic acid, sodium butyrate, and salts thereof; opioid peptides; a peptide comprising the tripeptide GGF; and morphinans, such as naloxone, naltrexone, 3-hydroxy-morphinan and dextromethorphan.
FILED	Thursday, July 03, 2014
APPL NO	14/323557
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/46 (20130101) A61K 31/485 (20130101) A61K 38/06 (20130101) A61K 38/08 (20130101) Original (OR) Class A61K 38/33 (20130101)
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09498517 — Stanniocalcin-1 (STC-1) therapy for treatment of retinal diseases

US 09498517	Rosa et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Scott and White Healthcare (Temple, Texas); The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	Scott and White Healthcare (Temple, Texas); The Texas A and M University System (College Station, Texas)
INVENTOR(S)	Robert Rosa (Holland, Texas); Gavin W. Roddy (Temple, Texas); Darwin J. Prockop (Philadelphia, Pennsylvania)
ABSTRACT	The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
FILED	Wednesday, July 01, 2015
APPL NO	14/789389
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 35/28 (20130101) A61K 38/22 (20130101) Original (OR) Class A61K 38/1709 (20130101) Peptides C07K 14/575 (20130101)
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09498521 — Purification, characterization, and use of Clostridium botulinum neurotoxin BoNT/A3

US 09498521	Johnson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Eric Johnson (Madison, Wisconsin); William Tepp (Stoughton, Wisconsin); Guangyun Lin (Madison, Wisconsin)
ABSTRACT	Preparations of Clostridium botulinum neurotoxin BoNT/A3 and methods for using such preparations for treating a patient having a symptom in need of botulinum toxin therapy are provided herein.
FILED	Wednesday, September 26, 2012
APPL NO	13/627540
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/4893 (20130101) Original (OR) Class Peptides C07K 14/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Enzymes C12Y 304/24069 (20130101)
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09498526 — Human rotavirus vaccine strains and diagnostics

US 09498526	Jiang et al.
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Baoming Jiang (Duluth, Georgia); Roger I. Glass (Atlanta, Georgia); Yuhuan Wang (Lilburn, Georgia); Jon Gentsch (Atlanta, Georgia)
ABSTRACT	A vaccine composition and method of vaccination are provided useful for immunizing a subject against a rotavirus. The vaccines include rotavirus strains CDC-9 and CDC-66, fragments thereof, homologues thereof, or combinations thereof. Inventive vaccines may include a fragment of CDC-9, CDC-66, homologues thereof, or combinations thereof. Methods of inducing an immunological response are provided by administering an inventive vaccine.
FILED	Monday, August 18, 2014
APPL NO	14/461663
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/15 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/005 (20130101) C07K 16/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2720/12334 (20130101) C12N 2720/12361 (20130101)
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09498533 — Drug delivery compositions and methods

US 09498533	Bronich et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Tatiana K. Bronich (Omaha, Nebraska); Alexander V. Kabanov (Chapel Hill, North Carolina); Jong Oh Kim (Syeongsan-buk-do, South Korea)
ASSIGNEE(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S)	Tatiana K. Bronich (Omaha, Nebraska); Alexander V. Kabanov (Chapel Hill, North Carolina); Jong Oh Kim (Syeongsan-buk-do, South Korea)
ABSTRACT	The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.
FILED	Wednesday, April 04, 2012
APPL NO	14/001084
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/704 (20130101) A61K 47/34 (20130101) Original (OR) Class
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09498537 — Method of enhancing efficacy of blood transfusions

US 09498537	Acharya et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) U.S. Public Health Service (USPHS)
APPLICANT(S)	Seetharama A. Acharya (Cresskill, New Jersey); Marcos Intaglietta (La Jolla, California)
ASSIGNEE(S)	Albert Einstein College of Medicine, Inc. (Bronx, New York); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Seetharama A. Acharya (Cresskill, New Jersey); Marcos Intaglietta (La Jolla, California)
ABSTRACT	A method of improving the efficacy of a blood transfusion into a subject is provided comprising administering a composition comprising an EAF PEGylated-blood protein into the subject, prior to, during, or subsequent to the blood transfusion.
FILED	Thursday, August 07, 2014
APPL NO	14/454059
ART UNIT	1675 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 35/14 (20130101) A61K 35/18 (20130101) A61K 38/38 (20130101) A61K 38/42 (20130101) A61K 38/385 (20130101) A61K 47/48215 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) C07K 14/765 (20130101) C07K 14/805 (20130101) C07K 2319/00 (20130101)
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09498546 — Synthesis and application of novel imaging agents conjugated to DPA 713 analogs for imaging inflammation

US 09498546	Pomper et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Martin Gilbert Pomper (Baltimore, Maryland); Haofan Wang (Rockville, Maryland); Catherine Anne Foss (Baltimore, Maryland)
ABSTRACT	The present invention provides analog compounds of DPA-713 which specifically bind the translocator protein (TSPO), which is upregulated in activated leukocytes, some malignant tumors and tissues involved in steroid biogenesis. These compounds are linked via a linking moiety to a variety of imaging agents, including, for example, near infra-red dyes. The compounds of the present invention are useful for both pre-clinical near-IR fluorescence imaging (NIRF) and use in optically-guided interventions including NIRF endoscopy. Methods of use in diagnosis and treatment of TSPO related disease are also provided.
FILED	Thursday, March 14, 2013
APPL NO	14/385090
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0017 (20130101) A61K 49/0032 (20130101) A61K 49/0052 (20130101) Original (OR) Class A61K 2123/00 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/57492 (20130101) G01N 2333/705 (20130101)
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09498566 — Selective cytopheresis devices and related methods thereof

US 09498566	Humes et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	H. David Humes (Ann Arbor, Michigan); Deborah Buffington (Ann Arbor, Michigan)
ASSIGNEE(S)	CYTOPHERX, INC. (Ann Arbor, Michigan); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	H. David Humes (Ann Arbor, Michigan); Deborah Buffington (Ann Arbor, Michigan)
ABSTRACT	The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
FILED	Monday, June 25, 2012
APPL NO	13/531872
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/34 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/34 (20130101) A61M 1/3621 (20130101) A61M 1/3633 (20130101) A61M 1/3666 (20130101) A61M 1/3672 (20130101) A61M 1/3679 (20130101) A61M 1/3687 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101)
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09498571 — Nitric oxide delivery devices

US 09498571	Hofler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Lajos Hofler (Oxford, United Kingdom); Mark E. Meyerhoff (Ann Arbor, Michigan); Dipankar Koley (Ann Arbor, Michigan)
ABSTRACT	A nitric oxide delivery device includes a housing that is permeable to nitric oxide. The surface of the housing is modified to detect surface charge or pH (e.g., due to cell adhesion). A working electrode (which is a copper-containing conductive material or a base material coated with a copper-containing conductive material) is positioned inside of the housing. A reference/counter electrode is also positioned inside of the housing, and is electrically isolated from the working electrode. A source of nitrite ions is to be contained within the housing such that it is in contact with the working electrode.
FILED	Thursday, March 28, 2013
APPL NO	13/852841
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14 (20130101) Original (OR) Class A61M 25/00 (20130101) A61M 25/0043 (20130101) A61M 2025/0057 (20130101) A61M 2202/0275 (20130101) A61M 2205/0233 (20130101) A61M 2205/0272 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/24 (20130101)
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09498651 — Methods of soft tissue emulsification using a mechanism of ultrasonic atomization inside gas or vapor cavities and associated systems and devices

US 09498651	Sapozhnikov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Aeronautics and Space Administration (NASA) National Space Biomedical Research Institute (NSBRI)
APPLICANT(S)	Oleg A. Sapozhnikov (Seattle, Washington); Michael R. Bailey (Seattle, Washington); Lawrence A. Crum (Bellevue, Washington); Tatiana D. Khokhlova (Seattle, Washington); Vera A. Khokhlova (Seattle, Washington); Julianna C. Simon (Kenmore, Washington); Yak-Nam Wang (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Oleg A. Sapozhnikov (Seattle, Washington); Michael R. Bailey (Seattle, Washington); Lawrence A. Crum (Bellevue, Washington); Tatiana D. Khokhlova (Seattle, Washington); Vera A. Khokhlova (Seattle, Washington); Julianna C. Simon (Kenmore, Washington); Yak-Nam Wang (Seattle, Washington)
ABSTRACT	The present technology is directed to methods of soft tissue emulsification using a mechanism of ultrasonic atomization inside gas or vapor cavities, and associated systems and devices. In several embodiments, for example, a method of non-invasively treating tissue includes pulsing ultrasound energy from the ultrasound source toward the target site in tissue. The ultrasound source is configured to emit high intensity focused ultrasound (HIFU) waves. The target site comprises a pressure-release interface of a gas or vapor cavity located within the tissue. The method continues by generating shock waves in the tissue to induce a lesion in the tissue at the target site. The method additionally includes characterizing the lesion based on a degree of at least one of a mechanical or thermal ablation of the tissue.
FILED	Wednesday, April 11, 2012
APPL NO	13/444466
ART UNIT	3737 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) Original (OR) Class A61N 2007/0039 (20130101)
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09499489 — Myxovirus therapeutics, compounds, and uses related thereto

US 09499489	Plemper et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Richard K. Plemper (Decatur, Georgia); James P. Snyder (Atlanta, Georgia); Aiming Sun (Atlanta, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia)
INVENTOR(S)	Richard K. Plemper (Decatur, Georgia); James P. Snyder (Atlanta, Georgia); Aiming Sun (Atlanta, Georgia)
ABSTRACT	This disclosure relates to antiviral compounds disclosed herein and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions. Typically, the pharmaceutical composition comprises a compound of formula I: Formula I, or salt, prodrug, or ester thereof wherein X, Y, and R¹and R¹⁰to R¹³are described herein.
FILED	Wednesday, October 24, 2012
APPL NO	14/352176
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 231/14 (20130101) Original (OR) Class C07D 401/12 (20130101)
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09499494 — Pyrimidine-2,4,6-triones for use in the treatment of amyotrophic lateral sclerosis

US 09499494	Kirsch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Donald R. Kirsch (Bedford, Massachusetts); Radhia Benmohamed (Tewksbury, Massachusetts); Anthony C. Arvanites (Medford, Massachusetts); Richard I. Morimoto (Evanston, Illinois); Guoyao Xia (Chicago, Illinois); Richard B. Silverman (Winnetka, Illinois)
ABSTRACT	The present invention relates to the identification of inventive pyrimidine-2,4,6-triones (PYT compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the inventive PYT compounds.
FILED	Friday, October 04, 2013
APPL NO	14/046333
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 239/62 (20130101) Original (OR) Class C07D 403/06 (20130101) C07D 403/14 (20130101) C07D 409/06 (20130101) C07D 413/06 (20130101)
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09499496 — Inhibitors of respiratory syncytial virus

US 09499496	Golden et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Mental Health (NIMH)
APPLICANT(S)	University of Kansas (Lawrence, Kansas); Southern Research Institute (Birmingham, Alabama)
ASSIGNEE(S)	University of Kansas (Lawrence, Kansas); Southern Research Institute (Birmingham, Alabama)
INVENTOR(S)	Jennifer E. Golden (Olathe, Kansas); Jeffrey Aube (Lawrence, Kansas); Denise S. Simpson (Lawrence, Kansas); Daniel P. Flaherty (Overland Park, Kansas); Daljit S. Matharu (Lawrence, Kansas); William E. Severson (Louisville, Kentucky); Lynn Rasmussen (Odenville, Alabama)
ABSTRACT	Described herein are compounds, pharmaceutical compositions and methods for treating a respiratory syncytial virus infection in a subject, or for inhibiting replication of respiratory syncytial virus.
FILED	Wednesday, June 05, 2013
APPL NO	14/405772
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Heterocyclic Compounds C07D 239/96 (20130101) Original (OR) Class C07D 405/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/18563 (20130101)
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09499517 — Substituted prolines / piperidines as orexin receptor antagonists

US 09499517	Kamenecka et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	Eolas Therapeutics, Inc. (Carlsbad, California)
ASSIGNEE(S)	Eolas Therapeutics, Inc. (Carlsbad, California)
INVENTOR(S)	Theodore M. Kamenecka (Palm Beach Gardens, Florida); Yuanjun He (Palm Beach Gardens, Florida); William Nguyen (Jupiter, Florida); Rong Jiang (Millersville, Maryland); Xinyi Song (Bristol, Pennsylvania); Robert Jason Herr (Voorheesville, New York); Qin Jiang (Latham, New York)
ABSTRACT	The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OX₁or OX₂, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, Alzheimer's disease, Parkinson's disease, Huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension, behavior disorder, mood disorder, manic depression, dementia, sex disorder, psychosexual disorder, or renal disease.
FILED	Wednesday, February 12, 2014
APPL NO	14/179432
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/445 (20130101) Heterocyclic Compounds C07D 401/12 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 417/06 (20130101) C07D 417/14 (20130101)
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09499521 — Inhibitors of cellular necrosis and related methods

US 09499521	Yuan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (Shanghai, China PRC)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Shanghai Institute of Organic Chemistry (Shanghai, China PRC)
INVENTOR(S)	Junying Yuan (Newton, Massachusetts); Yijun Zhou (Shanghai, China PRC); Shan Qian (Shanghai, China PRC); Dawei Ma (Shanghai, China PRC)
ABSTRACT	A compound having the following structure (I): or a pharmaceutically acceptable salt, prodrug, stereoisomer or tautomer thereof, is provided. Related compounds, methods for preparation of the same and uses of the compounds for treatment of various indications, including treatment of necrotic cell diseases and/or inflammation, are also provided.
FILED	Monday, June 27, 2016
APPL NO	15/194413
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 403/06 (20130101) Original (OR) Class
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09499558 — Compounds and methods for treating HIV

US 09499558	Ghosh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana); Hiroaki Mitsuya (Kumamoto, Japan)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Arun K. Ghosh (West Lafayette, Indiana); Bruno D. Chapsal (Astoria, New York); Hiroaki Mitsuya (Kumamoto, Japan); Cuthbert D Martyr (Lafayette, Indiana)
ABSTRACT	Inhibitors of HIV-1 protease and compositions containing them are described. Use of the inhibitors and compositions containing them to treat HIV, AIDS, and AIDS-related diseases is described.
FILED	Tuesday, April 21, 2015
APPL NO	14/692498
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 493/04 (20130101) Original (OR) Class
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09499564 — CDK inhibitors

US 09499564	Tavares et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	G1 Therapeutics, Inc. (Research Triangle Park, North Carolina)
ASSIGNEE(S)	G1 Therapeutics, Inc. (Research Triangle Park, North Carolina)
INVENTOR(S)	Francis X. Tavares (Durham, North Carolina); Jay C. Strum (Hillsborough, North Carolina)
ABSTRACT	Compounds of formulae I, II or III, and pharmaceutically acceptable salts thereof, are useful as CDK inhibitors.
FILED	Thursday, May 14, 2015
APPL NO	14/712582
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/499 (20130101) Heterocyclic Compounds C07D 487/14 (20130101) C07D 487/20 (20130101) C07D 498/14 (20130101) Original (OR) Class
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09499574 — Arsenoplatin anti-cancer agents

US 09499574	Miodragovic et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Denana U. Miodragovic (Chicago, Illinois); Thomas V. O'Halloran (Chicago, Illinois)
ABSTRACT	Disclosed are compound having the structure of formula (I): wherein M is Pt, Pd or Ni; Q is As, Sb or Bi; Z¹is N; Z²is O or S; L¹and L²are independently C(O), C—R¹or C—R²; X is a Lewis base and Y¹and Y²are independently oxygen- or sulfur-containing substituents, conjugates containing compounds of formula (I) and their use as chemotherapy agents.
FILED	Wednesday, August 14, 2013
APPL NO	14/421982
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/70 (20130101) C07F 9/94 (20130101) C07F 9/902 (20130101) C07F 15/0013 (20130101) C07F 15/045 (20130101) C07F 15/0066 (20130101) C07F 19/005 (20130101) Original (OR) Class
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09499575 — Synthesis of carbohydrate-based surfactants

US 09499575	Pemberton et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	The Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Jeanne E. Pemberton (Tucson, Arizona); Robin L. Polt (Tucson, Arizona); Raina M. Maier (Tucson, Arizona); Clifford S. Coss (Tucson, Arizona)
ABSTRACT	The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate-based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a hydrophobic compound.
FILED	Monday, September 30, 2013
APPL NO	14/041251
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/003 (20130101) C07F 9/94 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 15/04 (20130101) C07H 15/06 (20130101) Original (OR) Class C07H 15/14 (20130101)
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09499588 — Flaviviruses expressing the prM, E, and NS1 proteins of other flaviviruses and uses thereof

US 09499588	Mason et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Peter W. Mason (Somerville, Massachusetts); Tomohiro Ishikawa (Kobe, Japan)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Peter W. Mason (Somerville, Massachusetts); Tomohiro Ishikawa (Kobe, Japan)
ABSTRACT	This invention provides flavivirus vaccines that comprise live-attenuated flaviviruses and methods of making and using these vaccines. The flavivirus vaccines described herein possess higher potency due to in situ production of additional immunogens in a way that mimics viral infection and the vaccines have potential for higher potency, reducing costs for production and delivery.
FILED	Friday, July 22, 2011
APPL NO	13/136081
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/555 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24122 (20130101) C12N 2770/24143 (20130101) C12N 2770/24161 (20130101)
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09499589 — Chimeric vaccines

US 09499589	August et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Thomas August (Baltimore, Maryland); Ernesto Marques, Jr. (Baltimore, Maryland)
ABSTRACT	The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient.
FILED	Friday, May 17, 2013
APPL NO	13/897319
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/53 (20130101) A61K 2039/57 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/70596 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/06 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/86 (20130101) C12N 2740/16234 (20130101) C12N 2750/14143 (20130101)
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09499592 — Transcription activator-like effectors

US 09499592	Zhang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Energy (DOE) Office of Science (DOE-SC) Office of Science Consolidated Service Center (CSC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Brookline, Massachusetts); Sriram Kosuri (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Brookline, Massachusetts); Sriram Kosuri (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts)
ABSTRACT	Provided herein are compositions, kits and methods useful in the construction of designer transcription activator-like effector (dTALE) polypeptides.
FILED	Thursday, January 19, 2012
APPL NO	13/353662
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 14/195 (20130101) Original (OR) Class C07K 14/4705 (20130101) C07K 2319/00 (20130101) C07K 2319/09 (20130101) C07K 2319/60 (20130101) C07K 2319/80 (20130101)
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09499595 — Development of influenza A antivirals

US 09499595	Krug et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) U.S. Public Health Service (USPHS)
APPLICANT(S)	Robert M. Krug (Austin, Texas); Karen Y. Twu (San Mateo, California)
ASSIGNEE(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS (Austin, Texas)
INVENTOR(S)	Robert M. Krug (Austin, Texas); Karen Y. Twu (San Mateo, California)
ABSTRACT	The present invention includes compositions, methods and systems to isolate and characterize novel antiviral agents by contacting the antiviral agent with the F2F3 zinc fingers of a CPSF30 protein and an Influenza A NS1A protein; and determining whether the binding between the CPSF30 protein and the Influenza A NS1A protein is reduced.
FILED	Friday, September 04, 2009
APPL NO	12/554767
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) A61K 38/17 (20130101) A61K 39/0008 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/005 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/163 (20130101) C12N 5/0636 (20130101) C12N 7/00 (20130101) C12N 7/04 (20130101) C12N 2760/16111 (20130101) C12N 2760/16134 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/888 (20130101)
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09499600 — Long-acting single-chain insulin analogues

US 09499600	Weiss
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Michael Weiss (Moreland Hills, Ohio)
ABSTRACT	A single-chain insulin analog containing a basic side chain at position A8 (Arginine, Histidine, Lysine, or Ornithine), a basic side chain at position B29 (Arginine, Histidine, Lysine, or Ornithine), and a foreshortened C-domain of length 6-11 residues is provided. Residues C1 and C2 of the C-domain have a net negative charge of −1 or −2; C3 is chosen from a group consisting of Gly, Ala, Pro, or Ser; and the remaining C-domain segment is successively derived from the C-domain of IGF-II (RRSR (SEQ ID NO: 18), SRRSR (SEQ ID NO: 17), VSRRSR (SEQ ID NO: 16), RVSRRSR (SEQ ID NO: 15), or SRVSRRSR SEQ ID NO: 13). A method of treating a patient with diabetes mellitus or obesity comprises administering a physiologically effective amount of the insulin analog or a physiologically acceptable salt thereof to a patient.
FILED	Tuesday, November 05, 2013
APPL NO	14/440540
ART UNIT	1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/28 (20130101) Peptides C07K 14/62 (20130101) Original (OR) Class
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09499602 — Non-hemolytic LLO fusion proteins and methods of utilizing same

US 09499602	Paterson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Advaxis, Inc. (Princeton, New Jersey)
ASSIGNEE(S)	ADVAXIS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S)	Yvonne Paterson (Philadelphia, Pennsylvania); Paulo MaCiag (Long Grove, Illinois)
ABSTRACT	The present invention provides recombinant proteins or peptides comprising a mutated listeriolysin O (LLO) protein or fragment thereof, comprising a substitution or internal deletion of the cholesterol-binding domain or a portion thereof, fusion proteins or peptides comprising same, nucleotide molecules encoding same, and vaccine vectors comprising or encoding same. The present invention also provides methods of utilizing recombinant proteins, peptides, nucleotide molecules, and vaccine vectors of the present invention to induce an immune response to a peptide of interest.
FILED	Wednesday, February 12, 2014
APPL NO	14/163269
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/0208 (20130101) A61K 39/385 (20130101) A61K 2039/53 (20130101) A61K 2039/55522 (20130101) Peptides C07K 14/195 (20130101) C07K 14/705 (20130101) Original (OR) Class C07K 16/00 (20130101) C07K 2317/56 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101)
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09499607 — Anti-dengue virus antibodies and uses thereof

US 09499607	Sasisekharan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S)	Ram Sasisekharan (Cambridge, Massachusetts); Luke Nathaniel Robinson (Cambridge, Massachusetts); Kannan Tharakaraman (Arlington, Massachusetts)
ABSTRACT	The present invention provides, among other things, antibody agents (e.g., antibodies, and/or antigen-binding fragments thereof) that bind to DV epitopes, as well as compositions containing them and methods of designing, providing, formulating, using, identifying and/or characterizing them. In some embodiments, provided antibody agents show significant binding to a plurality of DV serotypes. In some embodiments, provided antibody agents show significant binding to all four DV serotypes. Such antibody agents are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of DV.
FILED	Thursday, July 25, 2013
APPL NO	13/951066
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/1081 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101)
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09499608 — Bispecific monoclonal antibody therapeutics against West Nile virus with improved CNS penetration

US 09499608	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) U.S. State Government State of Arizona
APPLICANT(S)	Qiang Chen (Scottsdale, Arizona); Huafang Lai (Scottsdale, Arizona); Junyun He (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Qiang Chen (Scottsdale, Arizona); Huafang Lai (Scottsdale, Arizona); Junyun He (Scottsdale, Arizona)
ABSTRACT	The plant-based production of a therapeutic antibody against West Nile Virus is disclosed.
FILED	Wednesday, June 06, 2012
APPL NO	14/124173
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/46 (20130101) C07K 16/1081 (20130101) C07K 16/2869 (20130101) C07K 16/2881 (20130101) C07K 19/00 (20130101) C07K 2317/13 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/41 (20130101) C07K 2317/64 (20130101) C07K 2317/66 (20130101) C07K 2317/76 (20130101) C07K 2317/90 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2317/734 (20130101)
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09499628 — Method of boosting the immune response in neonates

US 09499628	Way
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio)
ASSIGNEE(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S)	Sing Sing Way (Cincinnati, Ohio)
ABSTRACT	In an aspect, a method of augmenting an immune response in a subject in need thereof, comprising identifying the subject, and treating the subject to inhibit the immune suppressive effect of CD71⁺ cells is provided. Further provided is a method of preventing, treating or ameliorating an infection in a subject, comprising administering to the subject an agent that reduces the level of CD71⁺ cells in the subject.
FILED	Friday, June 13, 2014
APPL NO	14/304803
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2881 (20130101) Original (OR) Class
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09499629 — Use of chimeric antigen receptor-modified T-cells to treat cancer

US 09499629	June et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Carl H. June (Merion Station, Pennsylvania); Bruce L. Levine (Cherry Hill, New Jersey); David L. Porter (Springfield, Pennsylvania); Michael D. Kalos (Philadelphia, Pennsylvania); Michael C. Milone (Cherry Hill, New Jersey)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Carl H. June (Merion Station, Pennsylvania); Bruce L. Levine (Cherry Hill, New Jersey); David L. Porter (Springfield, Pennsylvania); Michael D. Kalos (Philadelphia, Pennsylvania); Michael C. Milone (Cherry Hill, New Jersey)
ABSTRACT	The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.
FILED	Friday, December 09, 2011
APPL NO	13/992622
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/177 (20130101) A61K 38/1774 (20130101) A61K 39/0011 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 48/005 (20130101) A61K 2039/505 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/525 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 14/70596 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2896 (20130101) Original (OR) Class C07K 16/3061 (20130101) C07K 2317/76 (20130101) C07K 2317/80 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 7/00 (20130101) C12N 15/85 (20130101) C12N 2501/515 (20130101) C12N 2510/00 (20130101) C12N 2740/15034 (20130101) C12N 2740/15043 (20130101)
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09499660 — Silicon-based cross coupling agents and methods of their use

US 09499660	Hoye et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Adam T. Hoye (Bala Cynwyd, Pennsylvania); Won-suk Kim (Seoul, South Korea); Dionicio Martinez-Solorio (Bala Cynwyd, Pennsylvania); Amos B. Smith, III (Merion, Pennsylvania); Luis Sanchez (Lewiston, New York); Rongbiao Tong (Kowloon, China PRC); Minh Huu Nguyen (Philadelphia, Pennsylvania); Bruno Melillo (Philadelphia, Pennsylvania)
ABSTRACT	Compositions and methods using silicon-based cross-coupling agents in the formation of carbon-carbon and carbon-nitrogen bonds are described.
FILED	Friday, June 07, 2013
APPL NO	14/405587
ART UNIT	1671 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 295/033 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1844 (20130101) C07F 7/1852 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) Original (OR) Class C08G 2261/418 (20130101) C08G 2261/3324 (20130101)
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09499786 — Enriched population of human pluripotent cells with Oct-4 and Sox2 integrated into their genome

US 09499786	Thomson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	James A. Thomson (Madison, Wisconsin); Junying Yu (Middleton, Wisconsin)
ABSTRACT	The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method.
FILED	Wednesday, February 13, 2013
APPL NO	13/766100
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0607 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/60 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2502/99 (20130101) C12N 2510/00 (20130101) C12N 2799/027 (20130101)
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09499791 — Skeletal muscle augmentation utilizing muscle-derived progenitor compositions, and treatments thereof

US 09499791	Payne et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Thomas Payne (Pittsburgh, Pennsylvania); Ronald Jankowski (Pittsburgh, Pennsylvania); Ryan Pruchnic (Pittsburgh, Pennsylvania); Michael Chancellor (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Thomas Payne (Pittsburgh, Pennsylvania); Ronald Jankowski (Pittsburgh, Pennsylvania); Ryan Pruchnic (Pittsburgh, Pennsylvania); Michael Chancellor (Pittsburgh, Pennsylvania)
ABSTRACT	The present invention provides muscle-derived progenitor cells (MDCs) that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction into a site of soft tissue. Also provided are methods of isolating MDCs. The invention further provides methods of using compositions comprising MDCs for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. The invention also relates to uses of MDCs for the treatment of cosmetic or functional conditions, including, but not limited to skeletal muscle weakness, muscular dystrophy, muscle atrophy, spasticity, myoclonus and myalgia. The invention also relates to the use of MDCs for the increase of skeletal muscle.
FILED	Friday, October 03, 2008
APPL NO	12/245379
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) C12N 5/0659 (20130101) Original (OR) Class C12N 2500/84 (20130101) C12N 2501/70 (20130101) C12N 2510/00 (20130101) C12N 2533/54 (20130101)
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09499800 — Methods of making and using chemically self assembled-nanorings

US 09499800	Wagner
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Carston R. Wagner (Minneapolis, Minnesota)
ABSTRACT	Provided herein are compounds, conjugates and methods for making lipid-chemically self-assembled nanorings (Lipid-CSANs) and using them to treat diseases and modify cell surfaces.
FILED	Tuesday, December 23, 2014
APPL NO	14/581538
ART UNIT	1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 47/481 (20130101) A61K 47/48046 (20130101) A61K 47/48215 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6561 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 2317/73 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/003 (20130101) Original (OR) Class C12N 9/96 (20130101) Enzymes C12Y 105/01003 (20130101)
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09499803 — Variant LovD polypeptide

US 09499803	Tang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Yi Tang (San Gabriel, California); Xue Gao (Los Angeles, California); Xinkai Xie (Los Angeles, California)
ABSTRACT	The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin. In particular, the disclosure teaches that variants of the LovD acyltransferase polypeptide can be engineered to exhibit properties that facilitate their use in the production of simvastatin and/or huvastatin. The materials and processes disclosed herein are designed so that fermentation facilities currently producing lovastatin can be converted to producing simvastatin and related compounds with minimal modifications.
FILED	Friday, February 06, 2015
APPL NO	14/615792
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) Original (OR) Class
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09499813 — Systems and methods for amplification and phage display

US 09499813	Derda et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Ratmir Derda (Cambridge, Massachusetts); Sindy K. Y. Tang (Stanford, California); George M. Whitesides (Newton, Massachusetts)
ASSIGNEE(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Ratmir Derda (Cambridge, Massachusetts); Sindy K. Y. Tang (Stanford, California); George M. Whitesides (Newton, Massachusetts)
ABSTRACT	Embodiments of various aspects described herein are directed to amplification of biological entities, for example, for phage display. In one aspect, members of a library of biological entities are encapsulated in separate compartments (e.g., in separate microfluidic droplets) and amplified. For example, by putting members of a phage display library into microfluidic droplets such that no droplet contains more than one member of the library, the library can be amplified without any substantial changes in population distributions, or other artifacts created due to differences in growth rates or amplification between different members of the library. In some cases, the volume of the compartments can be used to control the copy number of a biological entity during amplification. This can be advantageous, for example, in preserving diversity within a library by preventing rapidly amplifying biological entities from outcompeting slowly amplifying biological entities.
FILED	Friday, June 10, 2011
APPL NO	13/702603
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/02 (20130101) C40B 50/06 (20130101)
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09499817 — Antisense polynucleotides to induce exon skipping and methods of treating dystrophies

US 09499817	McNally
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Elizabeth McNally (Oak Park, Illinois)
ASSIGNEE(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S)	Elizabeth McNally (Oak Park, Illinois)
ABSTRACT	Antisense polynucleotides and their use in pharmaceutical compositions to induce exon skipping in targeted exons of the gamma sarcoglycan gene are provided, along with methods of preventing or treating dystrophic diseases such as Limb-Girdle Muscular Dystrophy. One aspect the disclosure provides an isolated antisense polynucleotide wherein the polynucleotide specifically hybridizes to an exon target region of a gamma sarcoglycan RNA, wherein the exon is selected from the group consisting of exon 4 (SEQ ID NO:1), exon 5 (SEQ ID NO: 2), exon 6 (SEQ ID NO: 3), exon 7 (SEQ ID NO: 4) and a combination thereof. In some embodiments, the antisense polynucleotide cannot form an RNase H substrate, and in further embodiments the antisense polynucleotide comprises a modified polynucleotide backbone.
FILED	Friday, September 06, 2013
APPL NO	14/426348
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48215 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/351 (20130101) C12N 2310/3535 (20130101) C12N 2320/30 (20130101) C12N 2320/33 (20130101)
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09499821 — Preventing or treating viral infection using an inhibitor of the LSD1 protein, a MAO inhibitor or an inhibitor of LSD1 and a MAO inhibitor

US 09499821	Kristie et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Thomas Kristie (Silver Spring, Maryland); Yu Liang (Rockville, Maryland); Jodi Vogel (Bethesda, Maryland)
ABSTRACT	An embodiment of the invention provides a method of preventing or treating a viral infection of a host, comprising administering to the host an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor. Another embodiment of the invention provides a method of preventing or treating reactivation of a virus after latency in a host, comprising administering to the host an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor. Another embodiment of the invention provides a method of preventing or treating a viral infection in a mammal that has undergone, is undergoing, or will undergo an organ or tissue transplant, comprising administering to the mammal an effective amount of an inhibitor of the protein LSD1 and/or a monoamine oxidase inhibitor before, during, and/or after the organ or tissue transplant. The viral infection may be due to a herpesvirus, such as herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2), varicella zoster virus (VZV), or cytomegalovirus (CMV). The viral infection may also be due to an adenovirus, including types 1-5.
FILED	Monday, November 17, 2014
APPL NO	14/543321
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/15 (20130101) A61K 31/42 (20130101) A61K 31/137 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101)
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09499850 — Modified influenza virus for monitoring and improving vaccine efficiency

US 09499850	Hoffmann et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	St. Jude Children's Research Hospital (Memphis, Tennessee)
ASSIGNEE(S)	St. Jude Children's Research Hospital (Memphis, Tennessee)
INVENTOR(S)	Erich Hoffmann (Galveston, Texas); Aleksandr S. Lipatov (Atlanta, Georgia); Richard J. Webby (Memphis, Tennessee); Elena A. Govorkova (Cordova, Tennessee); Robert G. Webster (Memphis, Tennessee)
ABSTRACT	The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of specific HA residues, such as asparagine at position 223 of H5 HA, increase the sensitivity of the hemagglutinin inhibition (HI) assay by altering receptor specificity and/or antibody-antigen binding. HA molecules containing such substitutions will be useful in the development of diagnostic reference viruses and improved influenza vaccines.
FILED	Thursday, October 03, 2013
APPL NO	14/045097
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 2039/525 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) C07K 16/1018 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16161 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/11 (20130101) G01N 2469/20 (20130101)
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09499854 — Tyrosine kinase biosensors and methods of use

US 09499854	Parker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Laurie Louise Parker (Minneapolis, Minnesota); Andrew M. Lipchik (Palo Alto, California); Scott Charles Bolton (West Lafayette, Indiana)
ABSTRACT	The claims describe a process for designing and validating peptide-based substrates for a specified kinase. The process uses a rational approach to design peptides with a specific amino acid that is phosphorylated by a target tyrosine kinase, and upon phosphorylation shows an increased affinity for a lanthanide ion that results in an enhanced fluorescent signal. The process uses kinase specific input data sets, encodes the input into positional scoring matrices, analyses the positional scoring matrices in order to generate a candidate list of peptide sequences, compares the peptide sequences in the candidate list, substitutes residues at non-selective positions in selections from the candidate list with terbium binding residues, and then screens the substituted selections with different kinases in vitro.
FILED	Thursday, February 07, 2013
APPL NO	13/761968
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Original (OR) Class
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09499856 — DDR2 mutations in squamous cell lung cancer

US 09499856	Meyerson et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Broad Institute, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	The Board Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Matthew Meyerson (Concord, Massachusetts); Peter Hammerman (Jamaica Plain, Massachusetts); Alexis Ramos (Somerville, Massachusetts)
ABSTRACT	Methods for treating patients with squamous cell lung cancer, including detecting the presence of mutations in the discoidin domain receptor 2 (DDR2) gene.
FILED	Wednesday, May 01, 2013
APPL NO	13/875079
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101)
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09499867 — Methods for diagnosing and assessing risk of developing glomerulosclerosis

US 09499867	Pollak et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Martin Pollak (Brookline, Massachusetts); Elizabeth J. Brown (Dallas, Texas); Johannes Schlondorff (Brookline, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S)	Martin Pollak (Brookline, Massachusetts); Elizabeth J. Brown (Dallas, Texas); Johannes Schlondorff (Brookline, Massachusetts)
ABSTRACT	This document features method related to variants in the Inverted Formin 2 (INF2) gene that are susceptibility to focal segmental glomerulosclerosis (FSGS). For example, methods of using such variants for risk assessment and for diagnosing and optimizing treatment of FSGS are provided.
FILED	Tuesday, December 07, 2010
APPL NO	13/513447
ART UNIT	1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6811 (20130101) C12Q 1/6813 (20130101) C12Q 1/6816 (20130101) C12Q 1/6827 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/6893 (20130101) G01N 2800/347 (20130101)
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09500572 — Sample dispenser including an internal standard and methods of use thereof

US 09500572	Ouyang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Zheng Ouyang (West Lafayette, Indiana); He Wang (West Lafayette, Indiana); Nicholas E. Manicke (West Lafayette, Indiana); Robert Graham Cooks (West Lafayette, Indiana); Qian Yang (West Lafayette, Indiana); Jiangjiang Liu (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to a sample dispenser including an internal standard and methods of use thereof. In certain embodiments, the invention provides a fluid dispenser that includes a fluid chamber. A portion of an inner wall of the chamber includes an internal standard. The chamber is configured such that fluid introduced to the chamber must interact with the portion of the chamber wall that includes the internal standard prior to flowing through an outlet of the chamber. The dispenser additionally includes a member coupled to the chamber such that it can control movement of fluid within the chamber.
FILED	Monday, March 04, 2013
APPL NO	13/784094
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/28 (20130101) G01N 1/286 (20130101) Original (OR) Class G01N 2001/2893 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0009 (20130101) H01J 49/16 (20130101)
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09500630 — Ion generation using modified wetted porous materials

US 09500630	Cooks et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Zheng Ouyang (West Lafayette, Indiana); He Wang (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
FILED	Monday, January 04, 2016
APPL NO	14/987154
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/91 (20130101) G01N 30/95 (20130101) Original (OR) Class G01N 33/49 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/167 (20130101) H01J 49/168 (20130101) H01J 49/0404 (20130101) H01J 49/0409 (20130101) H01J 49/0431 (20130101)
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09500636 — Multiscale platform for coordinating cellular activity using synthetic biology

US 09500636	Prindle et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Arthur Prindle (San Diego, California); Phillip Samayoa (La Jolla, California); Jeff Hasty (Encinitas, California)
ABSTRACT	This invention provides a multiscale platform for coordinating behavior using synthetic biology. The platform reduces the impact of underlying noise, making outputs more coherent and reliable at the macroscopic level. In one aspect, the invention provides a frequency-modulated biosensor, comprising a microfluidic array comprising two or more separate colonies or populations of sensing cells to grow and communicate by gas exchange, wherein the colonies or populations of sensing cells output synchronized oscillating signals.
FILED	Friday, December 14, 2012
APPL NO	14/364207
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/1866 (20130101) Original (OR) Class
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09500641 — Red-shifted opsin molecules and uses thereof

US 09500641	Chuong et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Amy Chuong (Cambridge, Massachusetts); Nathan Klapoetke (Cambridge, Massachusetts); Brian Yichiun Chow (Chestnut Hill, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Xue Han (Chestnut Hill, Massachusetts)
ABSTRACT	Compositions and methods for altering cell activity and function by expressing a light-activated ion pump polypeptide in a cell and contacting the cell with light that activates the expressed light-activated ion pump polypeptide. In some aspects of the invention, a light-activated ion pump polypeptide is a modified haloarcula halorhodopsin polypeptide, for example, a modified Halo 57 polypeptide.
FILED	Tuesday, January 20, 2015
APPL NO	14/600635
ART UNIT	1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) Peptides C07K 14/215 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) C12N 5/0619 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5032 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 530/825 (20130101)
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09500653 — Small-molecule hydrophobic tagging of fusion proteins and induced degradation of same

US 09500653	Crews et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Craig M. Crews (New Haven, Connecticut); Hyun Seop Tae (New Haven, Connecticut); Ashley R. Schneekloth (New Market, Maryland); Taavi Neklesa (Orange, Connecticut); Thomas Sundberg (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Craig M. Crews (New Haven, Connecticut); Hyun Seop Tae (New Haven, Connecticut); Ashley R. Schneekloth (New Market, Maryland); Taavi Neklesa (Orange, Connecticut); Thomas Sundberg (New Haven, Connecticut)
ABSTRACT	The present invention includes compounds that are useful in perturbing or disrupting the function of a transmembrane or intracellular protein, whereby binding of a compound to the transmembrane or intracellular protein induces proteasomal degradation of the transmembrane or intracellular protein. The present invention further includes a method of inducing proteasomal degradation of a transmembrane or intracellular protein. The present invention further includes a method of identifying or validating a protein of interest as a therapeutic target for treatment of a disease state or condition.
FILED	Tuesday, December 06, 2011
APPL NO	13/992076
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48015 (20130101) Peptides C07K 1/13 (20130101) C07K 2319/20 (20130101) C07K 2319/95 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 33/5008 (20130101) G01N 2500/10 (20130101)
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09500654 — Methods for identifying protein-protein interactions

US 09500654	Tao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Weiguo Andy Tao (West Lafayette, Indiana); Changdeng Hu (West Lafayette, Indiana); Lingfel Zeng (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to methods for identifying protein-protein interactions. In certain aspects, methods of the invention involve conducting a protein-fragment complementation assay on a sample to form a protein-protein complex between two proteins in the sample that only transiently interact under physiological conditions, separating the complexes from the sample, and analyzing a protein of the complex using a mass spectrometry technique.
FILED	Friday, June 06, 2014
APPL NO	14/297824
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 33/6845 (20130101) G01N 33/6848 (20130101) G01N 2333/912 (20130101)
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09500658 — Kruppel-like factor 10 (KLF10) as a biomarker of endothelial progenitor cell dysfunction

US 09500658	Feinberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Mark W. Feinberg (Newton, Massachusetts); Akm Khyrul Wara (West Roxbury, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Mark W. Feinberg (Newton, Massachusetts); Akm Khyrul Wara (West Roxbury, Massachusetts)
ABSTRACT	The use of Kruppel-like Factor (KLF10) as a diagnostic and prognostic tool for peripheral artery disease and other disease conditions associated with reduced angiogenesis or endothelial progenitor cell dysfunction such as diabetes and stent thrombosis.
FILED	Friday, March 09, 2012
APPL NO	14/003852
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2333/4703 (20130101) G01N 2800/32 (20130101) G01N 2800/50 (20130101)
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09500671 — AFM-coupled microscale radiofrequency probe for magnetic resonance imaging and spectroscopy

US 09500671	Neu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)
INVENTOR(S)	Corey P. Neu (West Lafayette, Indiana); Babak Ziaie (West Lafayette, Indiana); Teimour Maleki-Jafarabadi (Camarillo, California); Charilaos Mousoulis (Lafayette, Indiana); Xin Xu (West Lafayette, Indiana)
ABSTRACT	A method of using a AFM/NMR probe, the method comprising the steps of injecting a sample to be analyzed with magnetic particles, introducing a probe into proximity with the sample, the probe capable of both transmitting and sensing electromagnetic radiation; generating a magnetic field via the probe, and adjusting the magnitude of the magnetic field to manipulate the magnetic particles within the sample.
FILED	Tuesday, November 11, 2014
APPL NO	14/538328
ART UNIT	2881 — Optics
CURRENT CPC	Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/02 (20130101) G01Q 60/38 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/302 (20130101) G01R 33/465 (20130101) G01R 33/4808 (20130101) G01R 33/5601 (20130101) G01R 33/34007 (20130101) G01R 33/34084 (20130101)
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09501822 — Computer-implemented platform for automated fluorescence imaging and kinetic analysis

US 09501822	Blanchard et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Scott Blanchard (New York, New York); Daniel Terry (New York, New York); James Munro (New Haven, Connecticut); Peter Geggier (New York, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	Scott Blanchard (New York, New York); Daniel Terry (New York, New York); James Munro (New Haven, Connecticut); Peter Geggier (New York, New York)
ABSTRACT	Automatically selecting time traces from a fluorescence experiment, in one aspect, may include capturing results of the fluorescence experiment in a moving image; localizing sources of fluorescence in the moving image; producing time traces of each fluorescent source by monitoring fluorescence intensity of said localized sources in the moving image over time; removing unuseful time traces from said produced time traces; and selecting useful time traces from said produced time traces based on one or more defined criteria. FRET traces from selected time traces may be further calculated and analyzed. A unified computer-implemented platform in one aspect may include tools to locate single molecules, extract traces, classify smFRET traces according to adjustable parameters, and quantify the kinetic parameters of FRET transitions using analytical procedures such as Hidden Markov Modeling (HMM) procedures.
FILED	Friday, January 27, 2012
APPL NO	13/982401
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 21/6456 (20130101) G01N 2021/6441 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class
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09503649 — Cooperative optical-imaging sensor array

US 09503649	Barrett et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Warfare Center (NAWC) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	UNIVERSITY OF WYOMING (Laramie, Wyoming)
ASSIGNEE(S)	UNIVERSITY OF WYOMING (Laramie, Wyoming)
INVENTOR(S)	Steven F. Barrett (Laramie, Wyoming); Michael J. Wilcox (Colorado Springs, Colorado); Donald C. Thelen, Jr. (Bozeman, Montana); David F. Cox (Tucson, Arizona)
ABSTRACT	An apparatus and method for providing image primitives, such as edge polarity, edge magnitude, edge orientation, and edge displacement, and derivatives thereof, for an object are described. The data are obtained substantially simultaneously and processed in parallel such that multiple objects can be distinguished from one another in real time.
FILED	Monday, December 31, 2012
APPL NO	13/732012
ART UNIT	2878 — Optics
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/58 (20130101) G06K 9/60 (20130101) Image Data Processing or Generation, in General G06T 7/403 (20130101) G06T 2200/28 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14601 (20130101) Pictorial Communication, e.g Television H04N 5/23296 (20130101) Original (OR) Class
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Department of Defense (DOD)

09498221 — Implantable medical devices having double walled microspheres

US 09498221	Kokai et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S)	Lauren E. Kokai (Santa Barbara, California); Kacey Gribbin Marra (Canonsburg, Pennsylvania)
ABSTRACT	An implantable medical device including at least one double-walled microsphere containing an active agent, and a biodegradable polymer layer containing the at least one double-walled microsphere.
FILED	Thursday, March 07, 2013
APPL NO	13/788879
ART UNIT	1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/1128 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/50 (20130101) A61K 9/5031 (20130101) A61K 38/185 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/54 (20130101) A61L 2430/32 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/22 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101)
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09498231 — On-board tool tracking system and methods of computer assisted surgery

US 09498231	Haider et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
ASSIGNEE(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S)	Hani Haider (Carter Lake, Iowa); Ibrahim Al-Shawi (Amman, Jordan); Osvaldo Andres Barrera (Omaha, Nebraska)
ABSTRACT	A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer aided surgery and the devices used during such procedures. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled using the OTT device. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure including the rate of and type of data processed depending upon a CAS mode.
FILED	Friday, March 15, 2013
APPL NO	13/842526
ART UNIT	3768 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/14 (20130101) A61B 17/1626 (20130101) A61B 17/1675 (20130101) A61B 17/1703 (20130101) Original (OR) Class A61B 17/1764 (20130101) A61B 34/20 (20160201) A61B 34/76 (20160201) A61B 2034/102 (20160201) A61B 2034/2057 (20160201) A61B 2090/064 (20160201) A61B 2090/3983 (20160201)
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09498292 — Single site robotic device and related systems and methods

US 09498292	Mondry et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S)	Jack Mondry (Stillwater, Minnesota); Shane Farritor (Lincoln, Nebraska); Eric Markvicka (Ravenna, Nebraska); Thomas Frederick (Omaha, Nebraska); Joseph Bartels (Lincoln, Nebraska)
ABSTRACT	The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various medical devices for in vivo medical procedures.
FILED	Friday, March 15, 2013
APPL NO	13/839422
ART UNIT	3769 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 19/2203 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2034/302 (20160201) A61B 2034/2048 (20160201) A61B 2034/2051 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0084 (20130101)
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09498499 — Imaging-aided gene therapy using mesenchymal stem cells as target-delivery vehicle

US 09498499	Cheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)
INVENTOR(S)	Zhen Cheng (Mountain View, California); Kai Chen (Sunnyvale, California); Xiaoyuan Chen (Potomac, Maryland)
ABSTRACT	Compositions and methods of use thereof encompass engineered mesenchymal stem cells as a vehicle to deliver secreted tissue necrosis factor-RGD4C fusion polypeptides for tumor treatment, thereby reducing side effects of TNF. A reporter gene can be included in vector constructs to monitor the localization and viability of engineered MSCs after administration into a recipient animal. The genetically modified mesenchymal stem cell can comprise an expression cassette comprising a nucleic acid sequence operably linked to a gene expression promoter and encoding the heterologous fusion polypeptide comprising a tissue necrotic factor region and an integrin-binding region. Another aspect of the disclosure encompasses embodiments of a method of modulating the proliferation of a targeted population of tumor cells by delivering a population of the genetically modified mesenchymal stem cells to tumor cells, allowing the mesenchymal stem cells to express the heterologous polypeptide, thereby reducing the proliferative capacity of the tumor cells.
FILED	Friday, April 19, 2013
APPL NO	14/395651
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 2502/99 (20130101)
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09498537 — Method of enhancing efficacy of blood transfusions

US 09498537	Acharya et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) U.S. Public Health Service (USPHS)
APPLICANT(S)	Seetharama A. Acharya (Cresskill, New Jersey); Marcos Intaglietta (La Jolla, California)
ASSIGNEE(S)	Albert Einstein College of Medicine, Inc. (Bronx, New York); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Seetharama A. Acharya (Cresskill, New Jersey); Marcos Intaglietta (La Jolla, California)
ABSTRACT	A method of improving the efficacy of a blood transfusion into a subject is provided comprising administering a composition comprising an EAF PEGylated-blood protein into the subject, prior to, during, or subsequent to the blood transfusion.
FILED	Thursday, August 07, 2014
APPL NO	14/454059
ART UNIT	1675 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 35/14 (20130101) A61K 35/18 (20130101) A61K 38/38 (20130101) A61K 38/42 (20130101) A61K 38/385 (20130101) A61K 47/48215 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) C07K 14/765 (20130101) C07K 14/805 (20130101) C07K 2319/00 (20130101)
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09498586 — Infusion pump system and related methods

US 09498586	Smisson, III et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Smisson-Cartledge Biomedical LLC (Macon, Georgia)
ASSIGNEE(S)	SMISSON-CARTLEDGE BIOMEDICAL LLC (Macon, Georgia)
INVENTOR(S)	Hugh F. Smisson, III (Macon, Georgia); Richard G. Cartledge (Fort Lauderdale, Florida); David C. Field (Snellville, Georgia); Harvey A. Lewis, Jr. (Port Orange, Florida); Frederick J. York (Longwood, Florida)
ABSTRACT	An infusion pump system including an infusion tubing for delivering a fluid, a heat exchanger cartridge in fluid communication with the infusion tubing and removably coupled to at least one thermal element for heating or cooling the fluid, a motor driven pump in mechanical communication with the infusion tubing and configured to pump the fluid through the infusion tubing and the heat exchanger cartridge, and a central controller in electrical communication with the motor driven pump and the at least one thermal element. The central controller is configured to selectively deliver the fluid to a patient without heating or cooling the fluid by causing the motor driven pump to pump the fluid through the infusion tubing and the heat exchanger cartridge while the thermal element is off.
FILED	Monday, June 30, 2014
APPL NO	14/319280
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/0281 (20130101) A61M 5/36 (20130101) A61M 5/44 (20130101) Original (OR) Class A61M 5/172 (20130101) A61M 5/365 (20130101) A61M 5/16831 (20130101) A61M 2205/127 (20130101) A61M 2206/10 (20130101) A61M 2206/14 (20130101)
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09498846 — Systems and methods for preventing or reducing contamination enhanced laser induced damage (C-LID) to optical components using gas phase additives

US 09498846	Weiller et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	Bruce H. Weiller (Santa Monica, California); Randy M. Villahermosa (Los Angeles, California); Jesse D. Fowler (Cypress, California)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Bruce H. Weiller (Santa Monica, California); Randy M. Villahermosa (Los Angeles, California); Jesse D. Fowler (Cypress, California)
ABSTRACT	Systems and methods for preventing or reducing contamination enhanced laser induced damage (C-LID) to optical components are provided including a housing enclosing an optical component, a container configured to hold a gas phase additive and operatively coupled to the housing; and a delivery system configured to introduce the gas phase additive from the container into the housing and to maintain the gas phase additive at a pre-selected partial pressure within the housing. The gas phase additive may have a greater affinity for the optical component than does a contaminant and may be present in an amount sufficient to inhibit laser induced damage resulting from contact between the contaminant and the optical component. The housing may be configured to maintain a sealed gas environment or vacuum.
FILED	Monday, March 29, 2010
APPL NO	12/749410
ART UNIT	1718 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/12 (20130101) Original (OR) Class B23K 26/123 (20130101) B23K 26/127 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/2222 (20130101) H01S 3/2391 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 137/8593 (20150401)
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09498934 — Grafted polymer surfaces for dropwise condensation, and associated methods of use and manufacture

US 09498934	Paxson et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Adam T. Paxson (Cambridge, Massachusetts); Jose L. Yagüe (Somerville, Massachusetts); Kripa K. Varanasi (Lexington, Massachusetts); Karen K. Gleason (Cambridge, Massachusetts); Andong Liu (Cambridge, Massachusetts)
ABSTRACT	Presented herein are articles and methods featuring substrates with thin, uniform polymeric films grafted (e.g., covalently bonded) thereupon. The resulting coating provides significant reductions in thermal resistance, drop shedding size, and degradation rate during dropwise condensation of steam compared to existing coatings. Surfaces that promote dropwise shedding of low-surface tension condensates, such as liquid hydrocarbons, are also demonstrated herein.
FILED	Thursday, February 12, 2015
APPL NO	14/620661
ART UNIT	1782 — Miscellaneous Articles, Stock Material
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) B05D 3/02 (20130101) B05D 5/08 (20130101) B05D 5/083 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) B32B 15/082 (20130101) Original (OR) Class B32B 2307/302 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/00 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/04 (20130101) F28F 13/182 (20130101) F28F 19/04 (20130101) F28F 21/06 (20130101) F28F 2245/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115) Y10T 428/1352 (20150115) Y10T 428/3154 (20150401) Y10T 428/24355 (20150115) Y10T 428/24851 (20150115)
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09499253 — Composite rotor blade for a reaction drive rotorcraft

US 09499253	White
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Robert Owen White (Orillia, Canada)
ASSIGNEE(S)	Groem Brothers Aviation, Inc. (, None)
INVENTOR(S)	Robert Owen White (Orillia, Canada)
ABSTRACT	Apparatus and methods are disclosed for designing and manufacturing a composite structure, such as a composite rotor blade spar or composite rotor blade. A first mold may define a first mold surface and a second mold may include a rigid layer and a heated layer secured to the rigid layer and defining a second mold surface. A plurality of heating elements embedded in the second mold may be activated according to different temperature progressions to cure portions of the uncured composite rotor blade positioned coextensive therewith. In some embodiments, the second mold defines a root portion and first and second branch portions. A shear web may be placed between the branch portions during curing. The blade spar may define a complete airfoil contour or have fairings secured thereto having lines extending therethrough to a tip jet. A tip jet mounting structure and blade root attachment apparatus are also disclosed.
FILED	Monday, November 14, 2011
APPL NO	13/373440
ART UNIT	2862 — Printing/Measuring and Testing
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/00 (20130101) Aeroplanes; Helicopters B64C 11/24 (20130101) Original (OR) Class B64C 11/26 (20130101) B64C 27/82 (20130101) Electric Digital Data Processing G06F 17/40 (20130101) G06F 19/00 (20130101)
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09499283 — Freeplay measurement device

US 09499283	Olszewski
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Anthony Olszewski (Leonardtown, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Anthony Olszewski (Leonardtown, Maryland)
ABSTRACT	A freeplay measurement device for measuring freeplay in a ruddervator includes a forward horseshoe assembly, an aft horseshoe assembly, a L-shaped locator, a connecting assembly, a load applicator, and a measuring device. The forward horseshoe assembly forms a half of an ellipse that can slip on the forward half of the tail. The aft horseshoe assembly forms a half of an ellipse that can slip on the aft half of the tail and ruddervator. The L-shaped locator is for aligning the forward horseshoe assembly on the tail and perpendicularly extends from the forward horseshoe assembly. The connecting assembly connects the forward horseshoe assembly and the aft horseshoe assembly when each is placed over the tail and the ruddervator. The load applicator is for applying loads on the ruddervator. The measuring device is for measuring the deflections of the ruddervator being tested, and is attached to the forward horseshoe assembly.
FILED	Monday, June 15, 2015
APPL NO	14/739244
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Aeroplanes; Helicopters B64C 13/28 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/0045 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/16 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/22 (20130101)
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09499574 — Arsenoplatin anti-cancer agents

US 09499574	Miodragovic et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Denana U. Miodragovic (Chicago, Illinois); Thomas V. O'Halloran (Chicago, Illinois)
ABSTRACT	Disclosed are compound having the structure of formula (I): wherein M is Pt, Pd or Ni; Q is As, Sb or Bi; Z¹is N; Z²is O or S; L¹and L²are independently C(O), C—R¹or C—R²; X is a Lewis base and Y¹and Y²are independently oxygen- or sulfur-containing substituents, conjugates containing compounds of formula (I) and their use as chemotherapy agents.
FILED	Wednesday, August 14, 2013
APPL NO	14/421982
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/70 (20130101) C07F 9/94 (20130101) C07F 9/902 (20130101) C07F 15/0013 (20130101) C07F 15/045 (20130101) C07F 15/0066 (20130101) C07F 19/005 (20130101) Original (OR) Class
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09499592 — Transcription activator-like effectors

US 09499592	Zhang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Energy (DOE) Office of Science (DOE-SC) Office of Science Consolidated Service Center (CSC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Brookline, Massachusetts); Sriram Kosuri (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Brookline, Massachusetts); Sriram Kosuri (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts)
ABSTRACT	Provided herein are compositions, kits and methods useful in the construction of designer transcription activator-like effector (dTALE) polypeptides.
FILED	Thursday, January 19, 2012
APPL NO	13/353662
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 14/195 (20130101) Original (OR) Class C07K 14/4705 (20130101) C07K 2319/00 (20130101) C07K 2319/09 (20130101) C07K 2319/60 (20130101) C07K 2319/80 (20130101)
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09499813 — Systems and methods for amplification and phage display

US 09499813	Derda et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Ratmir Derda (Cambridge, Massachusetts); Sindy K. Y. Tang (Stanford, California); George M. Whitesides (Newton, Massachusetts)
ASSIGNEE(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Ratmir Derda (Cambridge, Massachusetts); Sindy K. Y. Tang (Stanford, California); George M. Whitesides (Newton, Massachusetts)
ABSTRACT	Embodiments of various aspects described herein are directed to amplification of biological entities, for example, for phage display. In one aspect, members of a library of biological entities are encapsulated in separate compartments (e.g., in separate microfluidic droplets) and amplified. For example, by putting members of a phage display library into microfluidic droplets such that no droplet contains more than one member of the library, the library can be amplified without any substantial changes in population distributions, or other artifacts created due to differences in growth rates or amplification between different members of the library. In some cases, the volume of the compartments can be used to control the copy number of a biological entity during amplification. This can be advantageous, for example, in preserving diversity within a library by preventing rapidly amplifying biological entities from outcompeting slowly amplifying biological entities.
FILED	Friday, June 10, 2011
APPL NO	13/702603
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/02 (20130101) C40B 50/06 (20130101)
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09499856 — DDR2 mutations in squamous cell lung cancer

US 09499856	Meyerson et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Broad Institute, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	The Board Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Matthew Meyerson (Concord, Massachusetts); Peter Hammerman (Jamaica Plain, Massachusetts); Alexis Ramos (Somerville, Massachusetts)
ABSTRACT	Methods for treating patients with squamous cell lung cancer, including detecting the presence of mutations in the discoidin domain receptor 2 (DDR2) gene.
FILED	Wednesday, May 01, 2013
APPL NO	13/875079
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101)
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09499890 — High-strength, high-toughness steel articles for ballistic and cryogenic applications, and method of making thereof

US 09499890	Zhang
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Xian Jie Zhang (Rockville, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Xian Jie Zhang (Rockville, Maryland)
ABSTRACT	According to exemplary practice of the present invention, a steel composition includes, by weight, 0.07 to 0.15% C, 9 to 11% Ni, 0.8 to 1.2% Mo, 0.05 to 0.10% V, and further includes additives and/or impurities, with the balance being Fe. An iron alloy having such composition is produced and then undergoes heat treatment that includes quenching, lamellarization according to a 30 minute holding duration and a temperature span of 625° C. to 665° C., and tempering according to a 60 minute holding duration and a temperature span of 575° C. to 605° C. Exemplary embodiments of the inventive steel afford superior material properties including yield strength of at least 129 ksi, tensile strength of at least 157 ksi, elongation of at least 23%, and Charpy impact energy of at least 112 foot-pounds at −120° F.
FILED	Friday, September 19, 2014
APPL NO	14/491637
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/18 (20130101) C21D 6/001 (20130101) C21D 6/004 (20130101) C21D 6/005 (20130101) C21D 6/008 (20130101) C21D 9/42 (20130101) C21D 9/46 (20130101) Alloys C22C 38/001 (20130101) C22C 38/02 (20130101) C22C 38/04 (20130101) C22C 38/06 (20130101) C22C 38/08 (20130101) C22C 38/12 (20130101) C22C 38/14 (20130101) C22C 38/16 (20130101) C22C 38/42 (20130101) C22C 38/44 (20130101) C22C 38/46 (20130101) C22C 38/48 (20130101) C22C 38/50 (20130101) Original (OR) Class
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09499895 — Reactive materials and thermal spray methods of making same

US 09499895	Langan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Space and Missile Defense Command (SMDC) U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S)	Timothy Langan (Catonsville, Maryland); W. Mark Buchta (Ellicott City, Maryland); Michael A. Riley (Towson, Maryland)
ASSIGNEE(S)	Surface Treatment Technologies, Inc. (Halethorpe, Maryland)
INVENTOR(S)	Timothy Langan (Catonsville, Maryland); W. Mark Buchta (Ellicott City, Maryland); Michael A. Riley (Towson, Maryland)
ABSTRACT	The present invention relates to reactive materials formed by thermal spray techniques. The thermally sprayed reactive materials have low porosity and high structural integrity. The reactive materials are useful for applications such as shaped charges, thermite welding, near net shaped components and the like.
FILED	Monday, June 21, 2004
APPL NO	10/873411
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/04 (20130101) C23C 4/12 (20130101) Original (OR) Class C23C 24/04 (20130101) C23C 28/042 (20130101) C23C 28/42 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/032 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12507 (20150115) Y10T 428/12562 (20150115) Y10T 428/12569 (20150115)
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09499903 — Carbon nanotube foams with controllable mechanical properties

US 09499903	Raney et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Jordan R. Raney (Pasadena, California); Chiara Daraio (Pasadena, California)
ABSTRACT	Syntheses of carbon nanotubes (CNT) are disclosed. The syntheses can take place on a thermally oxidized silicon surface placed inside a furnace prior to a reaction. The setup can have many variables that could affect the resulting CNT arrays, including flow rate and composition of carrier gas, flow rate and composition of precursor solution, and temperature. By varying such variables the density of the resulting CNT arrays can be controlled.
FILED	Wednesday, April 29, 2015
APPL NO	14/700035
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0226 (20130101) C01B 31/0233 (20130101) C01B 31/0273 (20130101) C01B 31/0438 (20130101) C01B 2202/06 (20130101) C01B 2202/08 (20130101) C01B 2202/26 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/01 (20130101) C23C 16/26 (20130101) Original (OR) Class C23C 16/52 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24983 (20150115)
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09500426 — Sound suppressor

US 09500426	Salvador
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) United States Marine Corps (USMC) Marine Corps Systems Command (MARCORSYSCOM)
APPLICANT(S)	FLODESIGN, INC. (Wilbraham, Massachusetts)
ASSIGNEE(S)	DAVINCI ARMS LLC (Wilbraham, Massachusetts)
INVENTOR(S)	Joseph D Salvador (Wilbraham, Massachusetts)
ABSTRACT	A sound suppressor for a firearm includes a generally cylindrical housing having a proximal end and a distal end, a plurality of baffle elements removably and slidably received within the housing, the baffle elements defining a plurality of expansion chambers within the housing, and an end closure element received on the distal end of the housing.
FILED	Thursday, May 21, 2015
APPL NO	14/718246
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/30 (20130101) Original (OR) Class
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09500445 — Multi-layer matrix composite having improved energy absorption, dissipation and shock wave mitigation capabilities

US 09500445	Hsieh et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	U.S. Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Alex Jer-Yann Hsieh (Winchester, Massachusetts); Tanya L. Chantawansri (Abingdon, Maryland); Jan W. Andzelm (North East, Maryland)
ABSTRACT	The disclosure relates to matrix composites comprising high strain-rate sensitive elastomers in a multi-layer construct which provide ballistic-resistant material systems with enhanced protection against blast damage as well as ballistic impact. According to one embodiment, a matrix composite for impact resistance and blast mitigation formed in a multi-layer configuration may include: (a) one or more outer layers comprising poly(urethane urea) having a strain-rate sensitivity characteristic in the range of 1,000/sec to 1,000,000/sec; and (b) one or more inner layers comprising poly(urethane urea) having a strain-rate sensitivity characteristic in the range of 10,000/sec to 1,000,000/sec.
FILED	Tuesday, September 10, 2013
APPL NO	14/022837
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 2307/558 (20130101) B32B 2571/00 (20130101) B32B 2571/02 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 1/02 (20130101) F41H 1/08 (20130101) F41H 5/08 (20130101) F41H 5/0407 (20130101) F41H 5/0478 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/24942 (20150115) Y10T 428/31554 (20150401) Y10T 428/249969 (20150401)
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09500447 — Multi-frequency projected energy gun

US 09500447	Cannon, Jr.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Thomas Calvin Cannon, Jr. (La Plata, Maryland)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Thomas Calvin Cannon, Jr. (La Plata, Maryland)
ABSTRACT	A multi-frequency projected energy gun system and method delivers energy to a target. The method includes generating simultaneously at least two signals from a source, amplifying the signals, combining the signals, and transmitting the signals into a medium or a vacuous space. The source includes one or more of a plurality of waveform generators configured to simultaneously generate at least two signals simultaneously. The signals are amplified by a power amplifier configured to amplify the power of the at least two signals. The signals are transmitted by one or more of a plurality of antennas configured to transmit the at least two signals simultaneously into a medium or a vacuous space.
FILED	Tuesday, February 11, 2014
APPL NO	13/999320
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 13/0043 (20130101) Original (OR) Class F41H 13/0075 (20130101) F41H 13/0081 (20130101)
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09500454 — Mortar projectile with guided deceleration system for delivering a payload

US 09500454	Decker et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Ryan Decker (Hoboken, New Jersey); Oleg Yakimenko (Monterey, California); Michael Hollis (Flanders, New Jersey); Douglas Chesnulovitch (Sparta, New Jersey); Raymond Chaplin (Hopatcong, New Jersey); Gary Dundon (Rockaway, New Jersey); Gregory Farbanish (Randolph, New Jersey)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Ryan Decker (Hoboken, New Jersey); Oleg Yakimenko (Monterey, California); Michael Hollis (Flanders, New Jersey); Douglas Chesnulovitch (Sparta, New Jersey); Raymond Chaplin (Hopatcong, New Jersey); Gary Dundon (Rockaway, New Jersey); Gregory Farbanish (Randolph, New Jersey)
ABSTRACT	A new mortar projectile for use to resupply various payloads to distant troops. The mortar projectile has the capability of rapidly and accurately transporting the payloads to forward disposed combatants without interference of terrain or enemy action. The mortar projectile includes a shell body for housing the payload to be delivered, and a GPS-guided parafoil for delivering the payload to the designated remote target location.
FILED	Wednesday, January 14, 2015
APPL NO	14/596767
ART UNIT	3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/56 (20130101) Original (OR) Class F42B 30/10 (20130101)
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09500457 — Non-pyrotechnic, low observable tracer

US 09500457	Horch et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Matthew T. Horch (Hillsborough, New Jersey); Christel M. Kelly (New Providence, New Jersey); Garry P. Glaspell (Mechanicsville, Virginia)
ABSTRACT	A low observable photoluminescent tracer projectile, for use with a small caliber weapon at night—which utilizes a base phosphor material of Ca, Sr and S, or a base phosphor material of Y₂, O₂, and S—with a combination of minor dopant ingredients; which base phosphor material is mixed with a clear binder to form a photoluminescent material which is applied to the rear end, or base, of a small arms projectile as a thin layer; to which thin layer is added a layer of small retro-reflectors—whereby, when this projectile is fired from the weapon, the photoluminescent mixture will be activated and will be observable, using night vision at an angle of 0 to about 20 degrees from the rear end of the projectile.
FILED	Wednesday, January 13, 2016
APPL NO	14/994491
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/38 (20130101) F42B 33/02 (20130101) Original (OR) Class
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09500522 — Apparatus and method for detection of electromagnetic radiation using optical switches in an RF network

US 09500522	Mechtel et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Deborah Mechtel (Clarksville, Maryland); Brian Jenkins (Crofton, Maryland); Peter Joyce (Annapolis, Maryland); Samara Firebaugh (Annapolis, Maryland); Adam Goetz (Olathe, Kansas)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Deborah Mechtel (Clarksville, Maryland); Brian Jenkins (Crofton, Maryland); Peter Joyce (Annapolis, Maryland); Samara Firebaugh (Annapolis, Maryland); Adam Goetz (Olathe, Kansas)
ABSTRACT	Apparatuses and methods for identifying and characterizing an impingement by electromagnetic radiation on a structure's surface. An array of input and output radiofrequency transmission lines are connected by photoconductive switches that conduct only when exposed to incident electromagnetic radiation. Each input line is assigned a unique input RF frequency. If a switch is exposed to radiation, the connection between the corresponding input and output lines closes, and an RF signal is output from the output port connected to the closed switch, while if the switch is not exposed to the incident radiation, the connection remains open and no RF signal is output. By analyzing the frequencies of the signals output at a port, the location of the radiation incident on the structure can be determined.
FILED	Wednesday, June 10, 2015
APPL NO	14/735401
ART UNIT	2633 — Digital Communications
CURRENT CPC	Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/252 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4228 (20130101) Original (OR) Class G01J 9/00 (20130101)
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09500531 — Wavefront sensing apparatus, method and applications

US 09500531	Shi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	UNIVERSITY OF ROCHESTER (Rochester, New York)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Zhimin Shi (Tampa, Florida); Robert W. Boyd (Webster, New York); Mohammad Mirhosseini (Rochester, New York); Mehul Malik (Rochester, New York)
ABSTRACT	A wavefront sensing technique using Polarization Rotation INTerferometry (PRINT) provides a self-referencing, high-resolution, direct measurement of the spatially dependent phase profile of a given optical beam. A self-referencing technique is used to create a reference beam in the orthogonal polarization and a polarization measurement to measure the spatial-dependent polarization parameters to directly determine the absolute phase profile of the beam under test. A high-resolution direct measurement of the spatially-resolved phase profile of one or more optical beams is realized.
FILED	Tuesday, March 25, 2014
APPL NO	14/224353
ART UNIT	2886 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) G01J 9/02 (20130101) Original (OR) Class G01J 2009/0261 (20130101)
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09500539 — Directional slug calorimeter for heat flux measurements

US 09500539	Hubble
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	David O. Hubble (King George, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David O. Hubble (King George, Virginia)
ABSTRACT	A directional slug calorimeter is provided to enable accurate non-isotropic heat flux measurement in a high-temperature environment. The slug calorimeter includes a tubular member; a plurality of slots formed along a portion of an axial length of the tubular member, insulation disposed within the tubular member and within the plurality of slots; and thermocouples disposed with a thermocouple junction. The plurality of slots divide the tubular member into discrete segments. The thermocouples are disposed in a central region of each of the discrete segments.
FILED	Monday, June 02, 2014
APPL NO	14/293078
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) Original (OR) Class
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09500568 — Inflatable inlet for aerosol sampling

US 09500568	Wise
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Aberdeen Proving Ground (APG) Combat Capabilities Development Command (CCDC) Chemical Biological Center (CCDC CBC) Research, Development and Engineering Command (RDECOM) Edgewood Chemical Biological Center (ECBC)
APPLICANT(S)	U.S. Army Edgewood Chemical Biological Center (APG, Maryland)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Daniel G. Wise (Ellicott City, Maryland)
ABSTRACT	The present invention is directed to an air intake for an aerosol sampling device, the air intake being inflatable and deflatable.
FILED	Tuesday, February 19, 2013
APPL NO	13/770630
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2202 (20130101) Original (OR) Class
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09500591 — Plastic particle detector for detection of biological aerosol and other fluorescent materials

US 09500591	Goad et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Aberdeen Proving Ground (APG)
APPLICANT(S)	U.S. Army Edgewood Chemical and Biological Command (Apg, Maryland)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Aime P. Goad (Baltimore, Maryland); David W. Sickenberger (Bel Air, Maryland); Fiona E. Narayanan (Forest Hill, Maryland); Richard J. Kreis (Bel Air, Maryland); Lester D. Strauch, III (Bel Air, Maryland); Gary K. Kilper (Perry Hall, Maryland); Jerry B. Cabalo (Towson, Maryland); Harold S. Wylie (Elkton, Maryland); Anna Wong (Bel Air, Maryland)
ABSTRACT	A plastic particle detector for detecting biological and other fluorescent materials is disclosed. The detector detects the fluorescence and scattering signals from these materials using deep UV excitation. The detector is fabricated using plastic materials and exploits the properties of lower manufacturing costs, lower materials costs, light weight, ruggedness and assembly ease offered by plastics, while eliminating stray fluorescence signals ordinarily generated by plastic materials.
FILED	Friday, April 03, 2015
APPL NO	14/678395
ART UNIT	2884 — Optics
CURRENT CPC	Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2077/00 (20130101) B29K 2507/04 (20130101) B29K 2509/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 21/47 (20130101) G01N 21/645 (20130101) G01N 21/6486 (20130101) Original (OR) Class G01N 2021/6471 (20130101) G01N 2201/062 (20130101)
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09500623 — Synchronization of ion generation with cycling of a discontinuous atmospheric interface

US 09500623	Cooks et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Jason Duncan (Dayton, Indiana); Guangming Huang (West Lafayette, Indiana); Guangtao Li (Carmel, Indiana); Xin Yan (West Lafayette, Indiana); Ewa Sokol (West Lafayette, Indiana); Xin Li (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.
FILED	Monday, October 14, 2013
APPL NO	14/052815
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/62 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0445 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/24 (20150115)
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09500688 — Noise temperature extraction procedure for characterization of on-wafer devices

US 09500688	Boglione
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Luciano Boglione (Cambridge, Massachusetts)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Luciano Boglione (Cambridge, Massachusetts)
ABSTRACT	A procedure for obtaining noise temperatures of a field effect transistor (FET) embedded on a wafer through an analytical procedure which processes measured noise figure data over transistor's size P_dwithin a frequency range at constant voltage and current density. The parasitic elements associated with an electrical model of the embedding structures are determined. Then, for each of n=1, 2, . . . N FETs, the scattering parameters and noise figure F_meas,nare measured, the components of the core model, normalized to the periphery P_dare determined, and the noise contributions of the parasitic components are de-embedded from F_meas,n. The noise temperatures t_gs, t_ds, and t_gdare found by solving the equation $\frac{4 N_{i} G_{s} (F_{meas, n} - 1) - y_{s}^{+} C_{T_{A}} y_{s} - y_{s}^{+} T_{B, n} T_{A} C_{T_{C}} T_{A}^{+} T_{B, n}^{+} y_{s}}{P_{d_{n}}} = A_{n} t_{ds} + B_{n} t_{gs} + C_{n} t_{gd}$ using at least three values of F_meas,nand P_d,n. Finally, the noise temperatures T_gs, T_ds, and T_gdare found, where T_gs=t_gsT₀, T₀=290K; T_ds=t_dsT₀; and T_gd=t_gd*T₀.
FILED	Thursday, September 19, 2013
APPL NO	14/031373
ART UNIT	2863 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 29/26 (20130101) Original (OR) Class G01R 31/2626 (20130101)
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09500772 — Metafilm for loss-induced super-scattering and gain-induced absorption of electromagnetic wave

US 09500772	Feng
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Simin Feng (Waldorf, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Simin Feng (Waldorf, Maryland)
ABSTRACT	A metafilm is provided for operating on a photon at a defined wavelength, for super-scattering, absorption, and for laser absorber switch. The metafilm includes dimers and a conductive substrate for embedding the dimers in an array. Each dimer comprises a pair of a gain element and a loss element. The substrate, and the gain and loss elements have complex permittivity values. The metafilm super-scatters (e.g., lases) the photon in response to increasing the imaginary component of either the substrate or the loss element, and absorbs the photon in response to increasing the imaginary component of the gain element.
FILED	Monday, December 07, 2015
APPL NO	14/961613
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/1046 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/755 (20130101) Y10S 977/774 (20130101)
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09501450 — System and method for bio-optical environmental reconnaissance

US 09501450	Gould et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Richard W. Gould (Peal River, Louisiana); Jeffrey W. Book (Slidell, Louisiana); Mark S. Hulbert (Slidell, Louisiana); Andrew J. Quaid (New Orleans, Louisiana); Richard H. Smith (Picayune, Mississippi); Emery W. Hughes (Mandeville, Louisiana); Berry L. McCormick (Carriere, Mississippi); David N. McNeal (Baton Rouge, Louisiana); J Carey Harrington (Slidell, Louisiana)
ASSIGNEE(S)	The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S)	Richard W. Gould (Peal River, Louisiana); Jeffrey W. Book (Slidell, Louisiana); Mark S. Hulbert (Slidell, Louisiana); Andrew J. Quaid (New Orleans, Louisiana); Richard H. Smith (Picayune, Mississippi); Emery W. Hughes (Mandeville, Louisiana); Berry L. McCormick (Carriere, Mississippi); David N. McNeal (Baton Rouge, Louisiana); J Carey Harrington (Slidell, Louisiana)
ABSTRACT	System for collecting ocean data includes a trawl-resistant bottom mooring having a base unit and profiler on board. Method for collecting ocean data includes steps for receiving and executing a configuration file in the base unit and the profiler, collecting data, transmitting the data to a receiving station, and transferring to and archiving the data in the base unit.
FILED	Friday, January 25, 2013
APPL NO	13/750642
ART UNIT	2864 — Printing/Measuring and Testing
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/29 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 19/0092 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/38 (20130101) Electric Digital Data Processing G06F 17/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115)
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09501491 — File format article of manufacture

US 09501491	Heil et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Rodney Heil (Hope, Idaho); Jeffrey Zyla (Jackson, Michigan)
ABSTRACT	Embodiments of the invention are directed to a list of floating counts (LFC) apparatus for providing storage of tables of numerical data using a column-wise data table descriptive language with a non-transitory electronic-processor-readable medium executing an LFC storage computer program. The embodiments include an LFC computer program that is operatively associated with an electronic processor. An LFC computer file and at least one LFC file header that is operatively associated with the electronic processor and the LFC computer program. The LFC computer program is configured to store information in the LFC computer file. Tabular data is operatively-associated with the LFC computer file. At least one LFC file header at least partially describes the tabular data and is non-compressed and human readable.
FILED	Tuesday, July 01, 2014
APPL NO	14/320716
ART UNIT	2447 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 17/30153 (20130101) G06F 17/30179 (20130101) Original (OR) Class
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09501639 — Methods, systems, and media for baiting inside attackers

US 09501639	Stolfo et al.
FUNDED BY	Department of Homeland Security (DHS) Institute for Information Infrastructure Protection (I3P) Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Salvatore J. Stolfo (Ridgewood, New Jersey); Angelos D. Keromytis (New York, New York); Brian M. Bowen (New York, New York); Shlomo Hershkop (Brooklyn, New York); Vasileios P. Kemerlis (New York, New York); Pratap V. Prabhu (New York, New York); Malek Ben Salem (Wappingers Falls, New York)
ABSTRACT	Methods, systems, and media for providing trap-based defenses are provided. In accordance with some embodiments, a method for providing trap-based defenses is provided, the method comprising: generating decoy information based at least in part on actual information in a computing environment, wherein the decoy information is generated to comply with one or more document properties; embedding a beacon into the decoy information; and inserting the decoy information with the embedded beacon into the computing environment, wherein the embedded beacon provides a first indication that the decoy information has been accessed by an attacker and wherein the embedded beacon provides a second indication that differentiates between the decoy information and the actual information.
FILED	Monday, March 09, 2015
APPL NO	14/642401
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/554 (20130101) Original (OR) Class G06F 21/566 (20130101) G06F 2221/034 (20130101) G06F 2221/2123 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1466 (20130101)
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09501666 — Polymorphic computing architectures

US 09501666	Lockett et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) United States Marine Corps (USMC) Marine Corps Systems Command (MARCORSYSCOM)
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI INTERNATIONAL (Menlo Park, California)
INVENTOR(S)	Christopher S. Lockett (Santa Clara, California); Scott A. Oberg (Paso Robles, California); Sean M. Forsberg (San Luis Obispo, California); Hassen Saidi (Menlo Park, California); Jeffrey E. Casper (San Carlos, California)
ABSTRACT	Polymorphic computing architectures can support and control separate, independently executable domains and other components on a computing platform. In some embodiments, the architectures may control the different domains and/or components according to different purposes. In some embodiments, the architectures can control domains and/or components to enforce a desired “purpose” of a domain/component while simultaneously denying a corresponding “anti-purpose”.
FILED	Friday, October 11, 2013
APPL NO	14/052266
ART UNIT	2494 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 9/542 (20130101) G06F 21/00 (20130101) G06F 21/60 (20130101) G06F 21/74 (20130101) Original (OR) Class G06F 21/575 (20130101) G06F 2221/2101 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/20 (20130101) Wireless Communication Networks H04W 12/06 (20130101)
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09501699 — Systems and methods for estimating the geographic location at which image data was captured

US 09501699	Kim et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	Hakjae Kim (Lorton, Virginia); Warren Dixon (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	Hakjae Kim (Lorton, Virginia); Warren Dixon (Gainesville, Florida)
ABSTRACT	In some embodiments, a system and method for estimating the geographical location at which image data was captured with a camera identifies matching feature points between the captured images, estimates a pose of the camera during the image capture from the feature points, performs geometric reconstruction of a scene in the images using the estimated pose of the camera to obtain a reconstructed scene, and compares the reconstructed scene to overhead images of known geographical origin to identify potential matches.
FILED	Saturday, May 12, 2012
APPL NO	14/004972
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) Original (OR) Class G06K 9/6211 (20130101) Image Data Processing or Generation, in General G06T 7/0018 (20130101)
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09501926 — Two wire sonar telemetry

US 09501926	Meninno et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Justin T Meninno (Fall River, Massachusetts); Michael J Obara (North Kingstown, Rhode Island)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Justin T Meninno (Fall River, Massachusetts); Michael J Obara (North Kingstown, Rhode Island)
ABSTRACT	The invention is a two wire telemetry system for an entire towed underwater acoustic sonar array system wherein power and data signals are now shared on a single wire (with a second wire as return) throughout the towed array. Ship electrical power is transmitted from a direct current source onto the tow cable for all of the array nodes to operate on. Downlink commands are also sent to the array nodes via the tow cable. Uplink data is sent up the tow cable to the towing vessel for data storage. A bi-directional time sharing communication protocol allows each node on the array as well as the command and control on the towing vessel a portion of time to transmit signals.
FILED	Wednesday, September 30, 2015
APPL NO	14/870069
ART UNIT	2685 — Selective Communication
CURRENT CPC	Transmission Systems for Measured Values, Control or Similar Signals G08C 19/22 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/16 (20130101)
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09502087 — Electrically gated three-terminal circuits and devices based on spin hall torque effects in magnetic nanostructures apparatus, methods and applications

US 09502087	Buhrman et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	Robert A. Buhrman (Ithaca, New York); Daniel C. Ralph (Ithaca, New York); Chi-Feng Pai (Ithaca, New York); Luqiao Liu (Ithaca, New York)
ABSTRACT	3-terminal magnetic circuits and devices based on the spin-transfer torque (STT) effect via a combination of injection of spin-polarized electrons or charged particles by using a charge current in a spin Hall effect metal layer coupled to a free magnetic layer and application of a gate voltage to the free magnetic layer to manipulate the magnetization of the free magnetic layer for various applications, including non-volatile memory functions, logic functions and others. The charge current is applied to the spin Hall effect metal layer via first and second electrical terminals and the gate voltage is applied between a third electrical terminal and either of the first and second electrical terminals. The spin Hall effect metal layer can be adjacent to the free magnetic layer or in direct contact with the free magnetic layer to allow a spin-polarized current generated via a spin Hall effect under the charge current to enter the free magnetic layer. The disclosed 3-terminal magnetic circuits can also be applied to signal oscillator circuits and other applications.
FILED	Thursday, December 31, 2015
APPL NO	14/986331
ART UNIT	2824 — Semiconductors/Memory
CURRENT CPC	Static Stores G11C 11/16 (20130101) G11C 11/18 (20130101) G11C 11/161 (20130101) Original (OR) Class G11C 11/1673 (20130101) G11C 11/1675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/228 (20130101) H01L 43/04 (20130101) H01L 43/06 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/065 (20130101)
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09502141 — Surface sediment core catcher

US 09502141	Rosen et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Gunther H. Rosen (San Diego, California); David Bart Chadwick (San Diego, California); Brittney Nguyen (San Diego, California); Hoa G Nguyen (San Diego, California); Aaron B. Burmeister (La Mesa, California)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Gunther H. Rosen (San Diego, California); David Bart Chadwick (San Diego, California); Brittney Nguyen (San Diego, California); Hoa G Nguyen (San Diego, California); Aaron B. Burmeister (La Mesa, California)
ABSTRACT	A core catcher comprising: a cap configured to be secured to a first end of a core liner such that when the first end of the core liner is inserted into sediment a sample sediment core enters the core liner through the cap; a cross-beam coupled to the cap and mounted across the first end of the core liner such that a cross-section of the first end of the core liner is divided into two openings; a flexible member secured to the cross-beam such that the flexible member, the cross-beam, and the cap form a dual-flap valve designed to allow the sediment core to enter the core liner through the two openings and to prevent the sediment core from escaping the core liner through the cap.
FILED	Wednesday, March 05, 2014
APPL NO	14/197493
ART UNIT	3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Nuclear Reactors G21C 9/016 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101)
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09502330 — Coolant distribution structure for monolithic microwave integrated circuits (MMICs)

US 09502330	Gupta et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Anurag Gupta (Canton, Massachusetts); David H. Altman (Framingham, Massachusetts); Jason G. Milne (Hawthorne, California); Christopher R. Koontz (Manhattan Beach, California)
ABSTRACT	A coolant distribution structure for an MMIC having: an input/output layer with an input port for receiving a coolant for transmission to coolant channels in the MMIC and an output port for exiting the coolant after such coolant has cooled active devices in the MMIC, a coolant pass-through layer to receive the coolant from the input port and having structure to inhibit such received coolant from passing directly to the output port, a coolant distribution layer for receiving coolant passing from the coolant pass-through layer and distributing such received coolant to the cooling channels to absorb heat generated by the active devices and then directing heated coolant to the coolant distribution layer and out of the porting layer via the pass-through layer. The coolant pass-through layer has a structure configured to inhibit such heated coolant from passing directly to the input port prior to such heated absorbed coolant being transmitted to the output port.
FILED	Tuesday, June 09, 2015
APPL NO	14/734372
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 23/367 (20130101) H01L 23/473 (20130101) Original (OR) Class H01L 23/3732 (20130101) H01L 2223/6683 (20130101)
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09502711 — Fabrication of biscrolled fiber using carbon nanotube sheet

US 09502711	Fang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Asian Office of Aerospace Research and Development (AOARD) Department of the Navy (DON) Office of Naval Research (ONR) Multidisciplinary University Research Initiative (MURI) Non-Profit Organization (NPO) Robert A. Welch Foundation National Science Foundation (NSF)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Shaoli Fang (Richardson, Texas); Marcio Dias Lima (Richardson, Texas); Xavier N. Lepro-Chavez (Richardson, Texas); Javier Carretero-Gonzalez (Dallas, Texas); Elizabeth Castillo-Martinez (Dallas, Texas); Raquel Ovalle-Robles (Sachse, Texas); Carter Sebastian Haines (Murphy, Texas); David Michael Novitski (Richardson, Texas); Mohammad H. Haque (Dallas, Texas); Chihye Lewis-Azad (Dallas, Texas); Mikhail Kozlov (Dallas, Texas); Anvar A. Zakhidov (McKinney, Texas); Ray H. Baughman (Dallas, Texas)
ABSTRACT	Fabrication of yarns or other shaped articles from materials in powder form (or nanoparticles or nanofibers) using carbon nanotube/nanofiber sheet as a platform (template). This includes methods for fabricating biscrolled yarns using carbon nanotube/nanofiber sheets and biscrolled fibers fabricated thereby.
FILED	Monday, December 14, 2015
APPL NO	14/967940
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/7007 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) A61L 17/04 (20130101) A61L 31/16 (20130101) A61L 31/024 (20130101) A61L 2300/108 (20130101) A61L 2300/414 (20130101) A61L 2300/418 (20130101) A61L 2400/12 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 21/063 (20130101) B01J 21/185 (20130101) B01J 23/42 (20130101) B01J 35/004 (20130101) B01J 35/0006 (20130101) B01J 35/06 (20130101) B01J 37/0215 (20130101) B01J 37/0238 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 3/12 (20130101) B05D 5/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/04 (20130101) C23C 14/58 (20130101) C23C 16/04 (20130101) C23C 16/56 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/16 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) Original (OR) Class H01M 4/96 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/0402 (20130101) H01M 4/587 (20130101) H01M 4/1391 (20130101) H01M 4/1393 (20130101) H01M 4/5825 (20130101) H01M 8/00 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Y02E 60/122 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2918 (20150115) Y10T 428/2929 (20150115)
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09502855 — Seeded Raman amplifier in a linear configuration for generating a 1240 nm laser

US 09502855	Henry et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
INVENTOR(S)	Leanne J. Henry (Albuquerque, New Mexico); Thomas M. Shay (Saint George, Utah); Gerald T. Moore (Albuquerque, New Mexico); Jacob R. Grosek (Albuquerque, New Mexico)
ABSTRACT	A third-order Stokes wavelength seed signal at the desired output wavelength of 1240 nm and a zeroth-order Stokes wavelength signal at 1066 nm are input into a Raman amplifier comprised of two Raman resonators in a linear configuration. The first resonator converts the zeroth-order Stokes wavelength signal at 1066 nm into a first-order Stokes wavelength signal at 1118 nm, and also outputs the third-order Stokes wavelength seed signal at 1240 nm. The second resonator then converts the 1118 nm output from the first resonator into a second-order Stokes wavelength signal at 1176 nm, which amplifies the 1240 nm seed signal power level. Each Raman resonator includes a photosensitive Raman fiber communicating with a plurality of high-reflector Bragg gratings. The linewidths of the second and third Stokes orders are controlled by adjusting the resonant bandwidth of the second Raman resonator by offsetting the respective center wavelengths of the high-reflector Bragg gratings.
FILED	Monday, March 07, 2016
APPL NO	15/063339
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/30 (20130101) H01S 3/302 (20130101) Original (OR) Class H01S 3/0675 (20130101) H01S 3/0826 (20130101) H01S 3/2316 (20130101) H01S 3/06754 (20130101) H01S 3/10092 (20130101) H01S 5/5027 (20130101)
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09502884 — Methods and systems for protecting DC circuits

US 09502884	Ghisla et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	University Of South Carolina (Columbia, South Carolina)
ASSIGNEE(S)	University of South Carolina (Columbia, South Carolina)
INVENTOR(S)	Ugo Ghisla (Columbia, Georgia); Roger Dougal (Columbia, South Carolina); Igor Kondratiev (Columbia, South Carolina)
ABSTRACT	Methods and systems for protecting DC circuits are provided. In an aspect, a method for controlling at least one protection circuit is disclosed. The method can monitor one or more parameters of the at least one protection circuit. One or more control signals can be selectively provided to a plurality of switches in the at least one protection circuit based on one or more parameters of the at least one protection circuit, in order to implement the appropriate protective topology based on one or more parameters of the at least one protection circuit. The method can be used to control a plurality of switches in the protection circuit and protect the DC circuit against short circuit, instabilities, and bus outages, and the like.
FILED	Friday, August 15, 2014
APPL NO	14/461347
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Emergency Protective Circuit Arrangements H02H 3/20 (20130101) H02H 3/38 (20130101) Original (OR) Class H02H 7/1213 (20130101) H02H 9/02 (20130101) H02H 9/025 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/32 (20130101) H02M 3/1582 (20130101)
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09502995 — Micro-hydraulic device

US 09502995	Najafi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Khalil Najafi (Ann Arbor, Michigan); Mahdi Sadeghi (Ann Arbor, Michigan); Rebecca L. Peterson (Ann Arbor, Michigan)
ABSTRACT	A micro-hydraulic device includes an enclosure. The enclosure includes a substrate having a first surface and a second surface distal to the first surface. The enclosure further includes a chamber defined between the first surface and the second surface. The chamber is defined by a wall substantially from the first surface to the second surface. The enclosure includes a first flexible membrane sealingly connected to the first surface and disposed over the chamber; and a second flexible membrane sealingly connected to the second surface disposed over the chamber distal to the first flexible membrane. The device further includes an internal fluid retained within the enclosure and a rigid electrode fixed within the chamber having an aperture therein. A flexible electrode is disposed on the second flexible membrane opposite the rigid electrode.
FILED	Wednesday, December 04, 2013
APPL NO	14/096409
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) Electric Machines Not Otherwise Provided for H02N 11/00 (20130101) Original (OR) Class
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09503118 — Multiplying analog to digital converter and method

US 09503118	Zhang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Jintao Zhang (Princeton, New Jersey); Zhuo Wang (Princeton, New Jersey); Naveen Verma (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Jintao Zhang (Princeton, New Jersey); Zhuo Wang (Princeton, New Jersey); Naveen Verma (Princeton, New Jersey)
ABSTRACT	A multiplying analog to digital converter (ADC) including a successive-approximation-register (SAR) analog to digital converter (ADC) having a sample input and a feedback input and an ADC output configured with a feedback path configured to couple the ADC output to a digital to analog converter. A feedback attenuator is disposed in the feedback path, the feedback attenuator being configured to attenuate a feedback signal coupled to the feedback input, the feedback attenuator being configured to provide analog multiplication observed at the ADC output. A barrel shifter is configured to provide digital multiplication of the ADC output. The feedback attenuator may be configured as a divider network. The feedback attenuator may be configured to provide attenuation using only passive components. The feedback attenuator may be configured as a capacitive divider network. The feedback attenuator may be configured to provide attenuation ranging between 1 and 0.5.
FILED	Monday, February 22, 2016
APPL NO	15/049752
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Coding; Decoding; Code Conversion in General H03M 1/442 (20130101) Original (OR) Class
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09503196 — N²times pulse energy enhancement using coherent addition of N orthogonally phase modulated periodic signals

US 09503196	Galvanauskas
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents Of The University Of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Almantas Galvanauskas (Ann Arbor, Michigan)
ABSTRACT	A method for increasing energy in a pulse optical beam is provided. The method may include: receiving an optical input beam having a period pulse train with a given repetition frequency; splitting the input beam into N optical signals; phase modulating each signal in the N optical signals at a different phase, such that the N optical signal are orthogonal to each other; and coherently combining each of the phase modulated signals into a single optical output beam.
FILED	Tuesday, June 11, 2013
APPL NO	14/403038
ART UNIT	2637 — Optical Communications
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) H01S 3/0092 (20130101) H01S 3/1307 (20130101) H01S 3/2383 (20130101) H01S 3/06754 (20130101) Transmission H04B 10/564 (20130101) Original (OR) Class H04B 10/5561 (20130101)
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09503202 — Underwater acoustic array, communication and location system

US 09503202	Cahalan et al.
FUNDED BY	Department of Defense (DOD) United States Special Operations Command (SOCOM)
APPLICANT(S)	Ceebus Technologies, LLC (Boulder, Colorado)
ASSIGNEE(S)	Ceebus Technologies, LLC (Boulder, Colorado)
INVENTOR(S)	Dennis Cahalan (Longmont, Colorado); Ted Noonan (Louisville, Colorado); Michel Hendricks (Boulder, Colorado); Jeffrey Croghan (Longmont, Colorado)
ABSTRACT	An underwater communication system comprises a plurality of network nodes for sending and receiving ultrasonic energy through water. In accordance with one aspect, each of the network nodes includes an array of two ultrasonic transducers positioned so as to define a line segment. Each node also includes a transceiver adapted to generate a code element, generate a data element, generate a modulation element, and combine the code element, the data element and the modulation element into an analog waveform. The system is further adapted to transmit the analog waveform through each of the ultrasonic transducers and receive the analog waveform generated by at least one of the network nodes.
FILED	Thursday, April 09, 2015
APPL NO	14/682731
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Transmission H04B 11/00 (20130101) H04B 13/02 (20130101) Original (OR) Class
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09503638 — High-resolution single-viewpoint panoramic camera and method of obtaining high-resolution panoramic images with a single viewpoint

US 09503638	Nguyen et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	UtopiaCompression Corporation (Los Angeles, California)
ASSIGNEE(S)	UtopiaCompression Corporation (Los Angeles, California)
INVENTOR(S)	Hieu Nguyen (Cypress, California); Sheng Liu (San Jose, California); Joseph Yadegar (Los Angeles, California)
ABSTRACT	The present invention provides a method and apparatus of obtaining single and video, high-resolution, panoramic images of a large field-of-view scene with a single viewpoint. The system consists of a segmented cap lens, multiple imaging sensors and imaging lenses. The cap lens is segmented to capture an individual sub-field of the entire panorama. In addition, the cap lens is optimized to relay the optical centers of the component cameras into a single viewpoint therefore reducing parallax errors. A high-resolution panoramic image with reduced artifacts is reconstructed by mosaicking multiple images taken by component cameras. The entire system is based upon refractive lenses to minimize the path length of light rays, enabling a relatively compact design for practical applications.
FILED	Monday, February 03, 2014
APPL NO	14/171134
ART UNIT	2486 — Recording and Compression
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/10 (20130101) G02B 13/06 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) Pictorial Communication, e.g Television H04N 5/2254 (20130101) H04N 5/23212 (20130101) H04N 5/23238 (20130101) Original (OR) Class
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09503649 — Cooperative optical-imaging sensor array

US 09503649	Barrett et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Warfare Center (NAWC) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	UNIVERSITY OF WYOMING (Laramie, Wyoming)
ASSIGNEE(S)	UNIVERSITY OF WYOMING (Laramie, Wyoming)
INVENTOR(S)	Steven F. Barrett (Laramie, Wyoming); Michael J. Wilcox (Colorado Springs, Colorado); Donald C. Thelen, Jr. (Bozeman, Montana); David F. Cox (Tucson, Arizona)
ABSTRACT	An apparatus and method for providing image primitives, such as edge polarity, edge magnitude, edge orientation, and edge displacement, and derivatives thereof, for an object are described. The data are obtained substantially simultaneously and processed in parallel such that multiple objects can be distinguished from one another in real time.
FILED	Monday, December 31, 2012
APPL NO	13/732012
ART UNIT	2878 — Optics
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/58 (20130101) G06K 9/60 (20130101) Image Data Processing or Generation, in General G06T 7/403 (20130101) G06T 2200/28 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14601 (20130101) Pictorial Communication, e.g Television H04N 5/23296 (20130101) Original (OR) Class
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09503681 — Simulated transparent display with augmented reality for remote collaboration

US 09503681	Popescu et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Voicu S Popescu (West Lafayette, Indiana); Juan P Wachs (West Lafayette, Indiana)
ABSTRACT	A method and system for remote collaboration and remote instruction utilizing computing devices at trainee site and mentor sites are disclosed. Annotations are superimposed onto a trainee's view of a view field displayed using a simulated transparent display with augmented reality (“AR”). By tracking the position of the trainee's view point, the position of the trainee's computing device, and the geometry of the view field, the annotations remain anchored to the image of the view field when the trainee device moves and/or when the view field deforms or becomes occluded.
FILED	Friday, May 27, 2016
APPL NO	15/167011
ART UNIT	2655 — Digital Audio Data Processing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 90/37 (20160201) A61B 2090/373 (20160201) Electric Digital Data Processing G06F 17/241 (20130101) G06F 19/3425 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6215 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101) G06T 7/0042 (20130101) G06T 7/0051 (20130101) G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 7/141 (20130101) Original (OR) Class
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09503747 — Threshold filtering of compressed domain data using steering vector

US 09503747	Satpathy et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Sudhir K. Satpathy (Hillsboro, Oregon); Sanu K. Mathew (Hillsboro, Oregon); Ram K. Krishnamurthy (Portland, Oregon)
ABSTRACT	In an embodiment, a processor includes a compression domain threshold filter coupled to a plurality of cores. The compression domain threshold filter is to: receive a sample vector of compressed data to be filtered; calculate, based at least on a first subset of the elements of the sample vector, an estimated upper bound value of a dot product of the sample vector and a steering vector; determine whether the estimated upper bound value of the dot product satisfies a filter threshold value; and in response to a determination that the estimated upper bound value of the dot product does not satisfy the filter threshold value, discard the sample vector without completion of a calculation of the dot product of the sample vector and the steering vector. Other embodiments are described and claimed.
FILED	Wednesday, January 28, 2015
APPL NO	14/607113
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 7/24 (20130101) G06F 7/5443 (20130101) Image Data Processing or Generation, in General G06T 7/0022 (20130101) G06T 7/0044 (20130101) Pictorial Communication, e.g Television H04N 19/48 (20141101) Original (OR) Class H04N 19/85 (20141101)
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Department of Energy (DOE)

09498135 — Microscopy imaging device with advanced imaging properties

US 09498135	Ghosh et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Kunal Ghosh (Mountain View, California); Laurie Burns (Menlo Park, California); Abbas El Gamal (Palo Alto, California); Mark J. Schnitzer (Palo Alto, Canada); Eric Cocker (Palo Alto, California); Tatt Wei Ho (Stanford, California)
ABSTRACT	Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm²and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.
FILED	Thursday, October 15, 2015
APPL NO	14/884556
ART UNIT	2485 — Recording and Compression
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/0071 (20130101) Original (OR) Class A61B 5/0082 (20130101) A61B 5/489 (20130101) A61B 90/20 (20160201) A61B 2090/306 (20160201) A61B 2503/40 (20130101) A61B 2503/42 (20130101) A61B 2562/04 (20130101) A61B 2562/0233 (20130101) A61B 2576/026 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 3/0087 (20130101) G02B 21/0008 (20130101) G02B 21/008 (20130101) G02B 21/16 (20130101) G02B 21/36 (20130101) G02B 21/361 (20130101) G02B 21/362 (20130101) G02B 21/365 (20130101) G02B 27/141 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/30016 (20130101) G06T 2207/30101 (20130101) Pictorial Communication, e.g Television H04N 5/2254 (20130101) H04N 5/2256 (20130101) H04N 5/23296 (20130101)
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09498617 — Conformally encapsulated multi-electrode arrays with seamless insulation

US 09498617	Tabada et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Melody Tabada (, None); Kedar G. Shah (Oakland, California); Vanessa Tolosa (Oakland, California); Satinderall S. Pannu (Pleasanton, California); Angela Tooker (Dublin, California); Terri Delima (Livermore, California); Heeral Sheth (Oakland, California); Sarah Felix (Oakland, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Phillipe J. Tabada (Roseville, California); Kedar G. Shah (Oakland, California); Vanessa Tolosa (Oakland, California); Satinderall S. Pannu (Pleasanton, California); Angela Tooker (Dublin, California); Terri Delima (Livermore, California); Heeral Sheth (Oakland, California); Sarah Felix (Oakland, California)
ABSTRACT	Thin-film multi-electrode arrays (MEA) having one or more electrically conductive beams conformally encapsulated in a seamless block of electrically insulating material, and methods of fabricating such MEAs using reproducible, microfabrication processes. One or more electrically conductive traces are formed on scaffold material that is subsequently removed to suspend the traces over a substrate by support portions of the trace beam in contact with the substrate. By encapsulating the suspended traces, either individually or together, with a single continuous layer of an electrically insulating material, a seamless block of electrically insulating material is formed that conforms to the shape of the trace beam structure, including any trace backings which provide suspension support. Electrical contacts, electrodes, or leads of the traces are exposed from the encapsulated trace beam structure by removing the substrate.
FILED	Monday, March 11, 2013
APPL NO	13/792708
ART UNIT	3766 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/04001 (20130101) A61B 2562/046 (20130101) A61B 2562/125 (20130101) A61B 2562/0209 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/044 (20130101) A61K 49/1806 (20130101) A61K 51/1217 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/04 (20130101) Original (OR) Class A61N 1/0529 (20130101) A61N 1/0551 (20130101)
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09499406 — Methods for the additive manufacturing of semiconductor and crystal materials

US 09499406	Stowe et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Security Complex and PANTEX Plant (Y-12) NNSA Critical Mission Site Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S)	Ashley C. Stowe (Knoxville, Tennessee); Douglas Speight (Knoxville, Tennessee)
ASSIGNEE(S)	Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Ashley C. Stowe (Knoxville, Tennessee); Douglas Speight (Knoxville, Tennessee)
ABSTRACT	A method for the additive manufacturing of inorganic crystalline materials, including: physically combining a plurality of starting materials that are used to form an inorganic crystalline compound to be used as one or more of a semiconductor, scintillator, laser crystal, and optical filter; heating or melting successive regions of the combined starting materials using a directed heat source having a predetermined energy characteristic, thereby facilitating the reaction of the combined starting materials; and allowing each region of the combined starting materials to cool in a controlled manner, such that the desired inorganic crystalline compound results. The method also includes, prior to heating or melting the successive regions of the combined starting materials using the directed heat source, heating the combined starting materials to facilitate initial reaction of the combined starting materials. The method further includes translating the combined starting materials and/or the directed heat source between successive locations. The method still further includes controlling the mechanical, electrical, photonic, and/or optical properties of the inorganic crystalline compound.
FILED	Friday, June 26, 2015
APPL NO	14/752048
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/085 (20130101) B01J 19/121 (20130101) B01J 19/128 (20130101) B01J 2219/0871 (20130101) B01J 2219/1203 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/881 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/06 (20130101)
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09499575 — Synthesis of carbohydrate-based surfactants

US 09499575	Pemberton et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	The Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Jeanne E. Pemberton (Tucson, Arizona); Robin L. Polt (Tucson, Arizona); Raina M. Maier (Tucson, Arizona); Clifford S. Coss (Tucson, Arizona)
ABSTRACT	The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate-based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a hydrophobic compound.
FILED	Monday, September 30, 2013
APPL NO	14/041251
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/003 (20130101) C07F 9/94 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 15/04 (20130101) C07H 15/06 (20130101) Original (OR) Class C07H 15/14 (20130101)
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09499592 — Transcription activator-like effectors

US 09499592	Zhang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Energy (DOE) Office of Science (DOE-SC) Office of Science Consolidated Service Center (CSC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Brookline, Massachusetts); Sriram Kosuri (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Brookline, Massachusetts); Sriram Kosuri (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts)
ABSTRACT	Provided herein are compositions, kits and methods useful in the construction of designer transcription activator-like effector (dTALE) polypeptides.
FILED	Thursday, January 19, 2012
APPL NO	13/353662
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 14/195 (20130101) Original (OR) Class C07K 14/4705 (20130101) C07K 2319/00 (20130101) C07K 2319/09 (20130101) C07K 2319/60 (20130101) C07K 2319/80 (20130101)
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09499699 — High durability solar absorptive coating and methods for making same

US 09499699	Hall et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Aaron C. Hall (Albuquerque, New Mexico); David P. Adams (Albuquerque, New Mexico)
ABSTRACT	The present invention relates to solar absorptive coatings including a ceramic material. In particular, the coatings of the invention are laser-treated to further enhance the solar absorptivity of the material. Methods of making and using such materials are also described.
FILED	Thursday, February 26, 2015
APPL NO	14/632838
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/32 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/08 (20130101) C23C 14/22 (20130101) C23C 14/34 (20130101) C23C 14/35 (20130101) C23C 14/0688 (20130101) C23C 16/40 (20130101) C23C 16/44 (20130101)
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09499772 — Methods of decontaminating surfaces and related compositions

US 09499772	Demmer et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho); Environmental Alternatives, Inc. (Keene, New Hampshire)
ASSIGNEE(S)	BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho)
INVENTOR(S)	Ricky L. Demmer (Idaho Falls, Idaho); Daniel Crosby (Keene, New Hampshire); Christopher J. Norton (Spofford, New Hampshire)
ABSTRACT	A composition of matter includes water, at least one acid, at least one surfactant, at least one fluoride salt, and ammonium nitrate. A method of decontaminating a surface includes exposing a surface to such a composition and removing the composition from the surface. Other compositions of matter include water, a fatty alcohol ether sulfate, nitrilotriacetic acid, at least one of hydrochloric acid and nitric acid, sodium fluoride, potassium fluoride, ammonium nitrate, and gelatin.
FILED	Wednesday, March 13, 2013
APPL NO	13/801493
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Cleaning in General; Prevention of Fouling in General B08B 3/08 (20130101) B08B 3/12 (20130101) Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 1/28 (20130101) C11D 3/26 (20130101) C11D 3/32 (20130101) Original (OR) Class C11D 3/042 (20130101) C11D 3/046 (20130101) C11D 3/048 (20130101) C11D 3/065 (20130101) C11D 3/222 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/002 (20130101) G21F 9/162 (20130101) G21F 9/167 (20130101)
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09499806 — Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same

US 09499806	Zhang et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Novozymes, Inc. (Davis, California)
ASSIGNEE(S)	Novozymes, Inc. (Davis, California)
INVENTOR(S)	Yu Zhang (Beijing, China PRC); Junxin Duan (Beijing, China PRC); Lan Tang (Beijing, China PRC); Wenping Wu (Beijing, China PRC)
ABSTRACT	The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED	Tuesday, April 26, 2016
APPL NO	15/139007
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Enzymes C12Y 302/01004 (20130101)
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09499824 — Transcriptional control in alicyclobacillus acidocaldarius and associated genes, proteins, and methods

US 09499824	Lee et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho)
ASSIGNEE(S)	Battelle Energy Alliance, LLC. (Idaho Falls, Idaho)
INVENTOR(S)	Brady D Lee (West Richland, Washington); David N Thompson (Idaho Falls, Idaho); William A Apel (Jackson, Wyoming); Vicki S Thompson (Idaho Falls, Idaho); David W Reed (Idaho Falls, Idaho); Jeffrey A Lacey (Idaho Falls, Idaho)
ABSTRACT	Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of modulating transcription or transcription or transcriptional control using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
FILED	Thursday, October 22, 2015
APPL NO	14/920598
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) C12N 15/635 (20130101) Original (OR) Class
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09499866 — Compositions and methods for detecting single nucleotide polymorphisms

US 09499866	Yeh et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Hsin-Chih Yeh (Austin, Texas); James Werner (Los Alamos, New Mexico); Jennifer S. Martinez (Dixon, New Mexico)
ABSTRACT	Described herein are nucleic acid based probes and methods for discriminating and detecting single nucleotide variants in nucleic acid molecules (e.g., DNA). The methods include use of a pair of probes can be used to detect and identify polymorphisms, for example single nucleotide polymorphism in DNA. The pair of probes emit a different fluorescent wavelength of light depending on the association and alignment of the probes when hybridized to a target nucleic acid molecule. Each pair of probes is capable of discriminating at least two different nucleic acid molecules that differ by at least a single nucleotide difference. The methods can probes can be used, for example, for detection of DNA polymorphisms that are indicative of a particular disease or condition.
FILED	Thursday, May 22, 2014
APPL NO	14/284776
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6881 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2563/107 (20130101) C12Q 2563/137 (20130101) C12Q 2563/155 (20130101) C12Q 2600/156 (20130101)
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09499880 — System and process for production of magnesium metal and magnesium hydride from magnesium-containing salts and brines

US 09499880	McGrail et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	B. Peter McGrail (Pasco, Washington); Satish K. Nune (Richland, Washington); Radha K. Motkuri (Richland, Washington); Vassiliki-Alexandra Glezakou (Richland, Washington); Phillip K. Koech (Richland, Washington); Tyler T. Adint (Richland, Washington); Leonard S. Fifield (Kennewick, Washington); Carlos A. Fernandez (Kennewick, Washington); Jian Liu (Richland, Washington)
ASSIGNEE(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S)	B. Peter McGrail (Pasco, Washington); Satish K. Nune (Richland, Washington); Radha K. Motkuri (Richland, Washington); Vassiliki-Alexandra Glezakou (Richland, Washington); Phillip K. Koech (Richland, Washington); Tyler T. Adint (Richland, Washington); Leonard S. Fifield (Kennewick, Washington); Carlos A. Fernandez (Kennewick, Washington); Jian Liu (Richland, Washington)
ABSTRACT	A system and process are disclosed for production of consolidated magnesium metal products and alloys with selected densities from magnesium-containing salts and feedstocks. The system and process employ a dialkyl magnesium compound that decomposes to produce the Mg metal product. Energy requirements and production costs are lower than for conventional processing.
FILED	Friday, March 06, 2015
APPL NO	14/640929
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/245 (20130101) B01J 2219/24 (20130101) Non-metallic Elements; Compounds Thereof; C01B 6/04 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 5/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/02 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/00 (20130101) C22B 3/02 (20130101) C22B 3/44 (20130101) C22B 26/22 (20130101) Original (OR) Class
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09499916 — Molecular molybdenum persulfide and related catalysts for generating hydrogen from water

US 09499916	Long et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jeffrey R. Long (Oakland, California); Christopher J. Chang (Berkeley, California); Hemamala I. Karunadasa (Palo Alto, California); Marcin Majda (Berkeley, California)
ABSTRACT	New metal persulfido compositions of matter are described. In one embodiment the metal is molybdenum and the metal persulfido complex mimics the structure and function of the triangular active edge site fragments of MoS₂, a material that is the current industry standard for petroleum hydro desulfurization, as well as a promising low-cost alternative to platinum for electrocatalytic hydrogen production. This molecular [(PY5W₂)MoS₂]^x+ containing catalyst is capable of generating hydrogen from acidic-buffered water or even seawater at very low overpotentials at a turnover frequency rate in excess of 500 moles H₂per mole catalyst per second, with a turnover number (over a 20 hour period) of at least 19,000,000 moles H₂per mole of catalyst.
FILED	Monday, September 21, 2015
APPL NO	14/859763
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/1815 (20130101) B01J 2231/62 (20130101) B01J 2531/16 (20130101) B01J 2531/46 (20130101) B01J 2531/56 (20130101) B01J 2531/62 (20130101) B01J 2531/64 (20130101) B01J 2531/66 (20130101) B01J 2531/72 (20130101) B01J 2531/0241 (20130101) B01J 2531/842 (20130101) B01J 2531/845 (20130101) B01J 2531/847 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/005 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Original (OR) Class C25B 3/04 (20130101)
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09499917 — Non-Faradaic electrochemical promotion of catalytic methane reforming for methanol production

US 09499917	Fan
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois)
ASSIGNEE(S)	Gas Technology Institute (Des Plaines, Illinois)
INVENTOR(S)	Qinbai Fan (Chicago, Illinois)
ABSTRACT	A method of converting methane to methanol at low temperatures utilizes a reactor including an anode, a cathode, a membrane separator between the anode and cathode, a metal oxide catalyst at the anode and a hydrogen recovery catalyst at the cathode. The method can convert methane to methanol at as rate exceeding the theoretical Faradaic rate due to the contribution of an electrochemical reaction occurring in tandem with a Faradaic reaction.
FILED	Monday, November 11, 2013
APPL NO	14/076445
ART UNIT	1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 3/02 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/132 (20151101)
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09500068 — Cavitation-based hydro-fracturing simulator

US 09500068	Wang et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Jy-An John Wang (Oak Ridge, Tennessee); Hong Wang (Oak Ridge, Tennessee); Fei Ren (Philadelphia, Pennsylvania); Thomas S. Cox (Oak Ridge, Tennessee)
ABSTRACT	An apparatus 300 for simulating a pulsed pressure induced cavitation technique (PPCT) from a pressurized working fluid (F) provides laboratory research and development for enhanced geothermal systems (EGS), oil, and gas wells. A pump 304 is configured to deliver a pressurized working fluid (F) to a control valve 306, which produces a pulsed pressure wave in a test chamber 308. The pulsed pressure wave parameters are defined by the pump 304 pressure and control valve 306 cycle rate. When a working fluid (F) and a rock specimen 312 are included in the apparatus, the pulsed pressure wave causes cavitation to occur at the surface of the specimen 312, thus initiating an extensive network of fracturing surfaces and micro fissures, which are examined by researchers.
FILED	Tuesday, March 25, 2014
APPL NO	14/224414
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/122 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/26 (20130101) Original (OR) Class E21B 49/006 (20130101) Pipe-line Systems; Pipe-lines F17D 1/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/567 (20130101) G01N 29/2418 (20130101) G01N 2203/0055 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 7/18 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0391 (20150401)
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09500083 — Apparatus and method to reduce wear and friction between CMC-to-metal attachment and interface

US 09500083	Cairo et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S)	U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Ronald Ralph Cairo (Simpsonville, South Carolina); Jason Robert Parolini (Greer, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina)
ABSTRACT	An apparatus to reduce wear and friction between CMC-to-metal attachment and interface, including a metal layer configured for insertion between a surface interface between a CMC component and a metal component. The surface interface of the metal layer is compliant relative to asperities of the surface interface of the CMC component. A coefficient of friction between the surface interface of the CMC component and the metal component is about 1.0 or less at an operating temperature between about 300° C. to about 325° C. and a limiting temperature of the metal component.
FILED	Monday, November 26, 2012
APPL NO	13/685230
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/83 (20130101) C04B 35/117 (20130101) C04B 35/185 (20130101) C04B 35/565 (20130101) C04B 35/803 (20130101) C04B 35/806 (20130101) C04B 37/026 (20130101) C04B 2235/963 (20130101) C04B 2235/5224 (20130101) C04B 2235/5228 (20130101) C04B 2235/5244 (20130101) C04B 2235/5248 (20130101) C04B 2237/38 (20130101) C04B 2237/64 (20130101) C04B 2237/66 (20130101) C04B 2237/76 (20130101) C04B 2237/84 (20130101) C04B 2237/123 (20130101) C04B 2237/365 (20130101) C04B 2237/405 (20130101) C04B 2237/592 (20130101) C04B 2237/708 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) Original (OR) Class F01D 5/3084 (20130101) F01D 5/3092 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/6033 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/007 (20130101) F23R 3/60 (20130101) F23R 2900/00017 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49336 (20150115)
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09500094 — Turbine with radial acting seal

US 09500094	Eng et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Darryl S Eng (Palm Beach Gardens, Florida); Todd A Ebert (West Palm Beach, Florida)
ASSIGNEE(S)	S and J DEISGN, LLC (Jupiter, Florida)
INVENTOR(S)	Darryl S Eng (Palm Beach Gardens, Florida); Todd A Ebert (West Palm Beach, Florida)
ABSTRACT	A floating brush seal in a rim cavity of a turbine in a gas turbine engine, where the floating brush seal includes a seal holder in which the floating brush seal floats, and a expandable seal that fits within two radial extending seal slots that maintains a seal with radial displacement of the floating brush seal and the seal holder.
FILED	Wednesday, September 18, 2013
APPL NO	14/030102
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/001 (20130101) Original (OR) Class
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09500325 — LED lamp incorporating remote phosphor with heat dissipation features

US 09500325	Tong et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Tao Tong (Oxnard, California); Ronan Letoquin (Fremont, California); Bernd Keller (Santa Barbara, California); Eric Tarsa (Goleta, California)
ASSIGNEE(S)	CREE, INC. (Durham, North Carolina)
INVENTOR(S)	Tao Tong (Oxnard, California); Ronan Letoquin (Fremont, California); Bernd Keller (Santa Barbara, California); Eric Tarsa (Goleta, California)
ABSTRACT	An LED lamp or bulb is disclosed that comprises a light source, a heat sink structure and a remote planar phosphor carrier having at least one conversion material. The phosphor carrier can be remote to the light sources and mounted to the heat sink so that heat from the phosphor carrier spreads into the heat sink. The phosphor carrier can comprise a thermally conductive transparent material and a phosphor layer, with an LED based light source mounted to the heat sink such that light from the light source passes through the phosphor carrier. At least some of the LED light is converted by the phosphor carrier, with some lamp embodiments emitting a white light combination of LED and phosphor light. The phosphor arranged according to the present invention can operate at lower temperature to thereby operate at greater phosphor conversion efficiency and with reduced heat related damage to the phosphor.
FILED	Wednesday, February 16, 2011
APPL NO	13/029025
ART UNIT	2875 — Optics
CURRENT CPC	Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/00 (20130101) F21K 9/56 (20130101) Original (OR) Class Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 29/004 (20130101) F21V 29/006 (20130101) F21V 29/75 (20150115) F21V 29/76 (20150115) F21V 29/85 (20150115) F21V 29/767 (20150115) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2101/02 (20130101) F21Y 2105/001 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/644 (20130101) H01L 2224/48091 (20130101) H01L 2224/48091 (20130101) H01L 2224/48247 (20130101) H01L 2224/73265 (20130101) H01L 2924/00014 (20130101)
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09500370 — Apparatus for mixing fuel in a gas turbine nozzle

US 09500370	Barker
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Carl Robert Barker (Simpsonville, South Carolina)
ABSTRACT	A fuel nozzle in a combustion turbine engine that includes: a fuel plenum defined between an circumferentially extending shroud and axially by a forward tube-sheet and an aft tube-sheet; and a mixing-tube that extends across the fuel plenum that defines a passageway connecting an inlet formed through the forward tube-sheet and an outlet formed through the aft tube-sheet, the mixing-tube comprising one or more fuel ports that fluidly communicate with the fuel plenum. The mixing-tube may include grooves on an outer surface, and be attached to the forward tube-sheet by a connection having a fail-safe leakage path.
FILED	Friday, December 20, 2013
APPL NO	14/136353
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/04 (20130101) F23R 3/10 (20130101) F23R 3/28 (20130101) F23R 3/30 (20130101) F23R 3/32 (20130101) F23R 3/045 (20130101) F23R 3/283 (20130101) F23R 3/286 (20130101) Original (OR) Class
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09500579 — System and method for detecting components of a mixture including tooth elements for alignment

US 09500579	Sommer et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Gregory Jon Sommer (Livermore, California); Ulrich Y. Schaff (Livermore, California)
ABSTRACT	Examples are described including assay platforms having tooth elements. An impinging element may sequentially engage tooth elements on the assay platform to sequentially align corresponding detection regions with a detection unit. In this manner, multiple measurements may be made of detection regions on the assay platform without necessarily requiring the starting and stopping of a motor.
FILED	Friday, April 18, 2014
APPL NO	14/256294
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) Original (OR) Class G01N 21/59 (20130101) G01N 21/64 (20130101)
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09500601 — Adaptive CT scanning system

US 09500601	Sampayan
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Stephen E. Sampayan (Manteca, California)
ABSTRACT	Apparatus, systems, and methods that provide an X-ray interrogation system having a plurality of stationary X-ray point sources arranged to substantially encircle an area or space to be interrogated. A plurality of stationary detectors are arranged to substantially encircle the area or space to be interrogated, A controller is adapted to control the stationary X-ray point sources to emit X-rays one at a time, and to control the stationary detectors to detect the X-rays emitted by the stationary X-ray point sources.
FILED	Tuesday, March 04, 2014
APPL NO	14/196914
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) Original (OR) Class G01N 2223/419 (20130101) G01N 2223/643 (20130101)
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09500773 — High voltage photoconductive switch package

US 09500773	Caporaso
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	George J. Caporaso (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	George J. Caporaso (Livermore, California)
ABSTRACT	A photoconductive switch having a wide bandgap material substrate between opposing electrodes, and a doped dielectric filler that is in contact with both the electrodes and the substrate at the triple point. The dielectric filler material is doped with a conductive material to make it partially or completely conducting, to minimize the field enhancement near the triple point both when the substrate is not conducting in the “off” state and when the substrate is rendered conducting by radiation in the “on” state.
FILED	Friday, June 07, 2013
APPL NO	13/913319
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Original (OR) Class
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09500930 — On-chip entangled photon source

US 09500930	Soh et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albququerque, New Mexico)
INVENTOR(S)	Daniel B. S. Soh (Pleasanton, California); Scott E. Bisson (Livermore, California)
ABSTRACT	Various technologies pertaining to an on-chip entangled photon source are described herein. A light source is used to pump two resonator cavities that are resonant at two different respective wavelengths and two different respective polarizations. The resonator cavities are coupled to a four-wave mixing cavity that receives the light at the two wavelengths and outputs polarization-entangled photons.
FILED	Wednesday, March 09, 2016
APPL NO	15/065528
ART UNIT	2874 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/39 (20130101) G02F 1/3526 (20130101) Original (OR) Class G02F 1/3536 (20130101)
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09501333 — Multiprocessor system with multiple concurrent modes of execution

US 09501333	Ahn et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Daniel Ahn (Yorktown Heights, New York); Luis H. Ceze (Urbana, Illinois); Dong Chen Chen (Croton-on-Hudson, New York); Alan Gara (Mount Kisco, New York); Philip Heidelberger (Cortlandt Manor, New York); Martin Ohmacht (Yorktown Heights, New York)
ABSTRACT	A multiprocessor system supports multiple concurrent modes of speculative execution. Speculation identification numbers (IDs) are allocated to speculative threads from a pool of available numbers. The pool is divided into domains, with each domain being assigned to a mode of speculation. Modes of speculation include TM, TLS, and rollback. Allocation of the IDs is carried out with respect to a central state table and using hardware pointers. The IDs are used for writing different versions of speculative results in different ways of a set in a cache memory.
FILED	Monday, December 30, 2013
APPL NO	14/143783
ART UNIT	2199 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/524 (20130101) Original (OR) Class G06F 12/08 (20130101)
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09501664 — Method, apparatus and system to compensate for drift by physically unclonable function circuitry

US 09501664	Hamlet
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Jason Hamlet (Albuquerque, New Mexico)
ABSTRACT	Techniques and mechanisms to detect and compensate for drift by a physically uncloneable function (PUF) circuit. In an embodiment, first state information is registered as reference information to be made available for subsequent evaluation of whether drift by PUF circuitry has occurred. The first state information is associated with a first error correction strength. The first state information is generated based on a first PUF value output by the PUF circuitry. In another embodiment, second state information is determined based on a second PUF value that is output by the PUF circuitry. An evaluation of whether drift has occurred is performed based on the first state information and the second state information, the evaluation including determining whether a threshold error correction strength is exceeded concurrent with a magnitude of error being less than the first error correction strength.
FILED	Monday, December 15, 2014
APPL NO	14/570704
ART UNIT	2496 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/71 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101)
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09501738 — Cellular computational platform and neurally inspired elements thereof

US 09501738	Okandan
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Murat Okandan (Edgewood, New Mexico)
ABSTRACT	A cellular computational platform is disclosed that includes a multiplicity of functionally identical, repeating computational hardware units that are interconnected electrically and optically. Each computational hardware unit includes a reprogrammable local memory and has interconnections to other such units that have reconfigurable weights. Each computational hardware unit is configured to transmit signals into the network for broadcast in a protocol-less manner to other such units in the network, and to respond to protocol-less broadcast messages that it receives from the network. Each computational hardware unit is further configured to reprogram the local memory in response to incoming electrical and/or optical signals.
FILED	Tuesday, August 13, 2013
APPL NO	13/966127
ART UNIT	2124 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/067 (20130101) Original (OR) Class
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09502203 — Electron beam gun with kinematic coupling for high power RF vacuum devices

US 09502203	Borchard
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Dymenso LLC (San Francisco, California)
ASSIGNEE(S)	Dymenso LLC (San Francisco, California)
INVENTOR(S)	Philipp Borchard (San Francisco, California)
ABSTRACT	An electron beam gun for a high power RF vacuum device has components joined by a fixed kinematic coupling to provide both precise alignment and high voltage electrical insulation of the components. The kinematic coupling has high strength ceramic elements directly bonded to one or more non-ductile rigid metal components using a high temperature active metal brazing alloy. The ceramic elements have a convex surface that mates with concave grooves in another one of the components. The kinematic coupling, for example, may join a cathode assembly and/or a beam shaping focus electrode to a gun stem, which is preferably composed of ceramic. The electron beam gun may be part of a high power RF vacuum device such as, for example, a gyrotron, klystron, or magnetron.
FILED	Monday, December 21, 2015
APPL NO	14/977110
ART UNIT	2879 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 23/06 (20130101) Original (OR) Class H01J 29/04 (20130101) H01J 29/58 (20130101) H01J 29/485 (20130101) H01J 2223/06 (20130101) H01J 2223/08 (20130101) H01J 2229/481 (20130101) H01J 2229/4831 (20130101)
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09502715 — Disordered anodes for Ni-metal rechargeable battery

US 09502715	Young et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Ovonic Battery Company, Inc. (Rochester Hills, Michigan)
ASSIGNEE(S)	Ovonic Battery Company, Inc. (Rochester Hills, Michigan)
INVENTOR(S)	Kwo-hsiung Young (Troy, Michigan); Lixin Wang (Ypsilanti, Michigan); William C. Mays (Commerce, Michigan)
ABSTRACT	An electrochemical cell is provided that includes a structurally and compositionally disordered electrochemically active alloy material as an anode active material with unexpected capacity against a nickel hydroxide based cathode active material. The disordered metal hydroxide alloy includes three or more transition metal elements and is formed in such a way so as to produce the necessary disorder in the overall system. When an anode active material includes nickel as a predominant, the resulting cells represent the first demonstration of a functional Ni/Ni cell.
FILED	Friday, January 23, 2015
APPL NO	14/603904
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/32 (20130101) H01M 4/52 (20130101) H01M 4/502 (20130101) H01M 4/523 (20130101) Original (OR) Class H01M 4/525 (20130101) H01M 10/30 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101)
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09502719 — Cathode catalysts for fuel cell application derived from polymer precursors

US 09502719	Serov et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Alexey Serov (Albuquerque, New Mexico); Barr Halevi (Albuquerque, New Mexico); Michael Robson (Albuquerque, New Mexico); Wendy Patterson (Albuquerque, New Mexico); Kateryna Artyushkova (Albuquerque, New Mexico); Plamen B Atanassov (Santa Fe, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Alexey Serov (Albuquerque, New Mexico); Barr Halevi (Albuquerque, New Mexico); Michael Robson (Albuquerque, New Mexico); Wendy Patterson (Albuquerque, New Mexico); Kateryna Artyushkova (Albuquerque, New Mexico); Plamen B Atanassov (Santa Fe, New Mexico)
ABSTRACT	A method of preparing M-N—C catalysts utilizing a sacrificial support approach and inexpensive and readily available polymer precursors as the source of nitrogen and carbon is disclosed. Exemplary polymer precursors include those that do not form complexes with iron, but which do complex with silica, for example, polyetheleneimine (PEI), Poly(2-ethyl-2-oxazoline), Poly(acrylamide-co-diallyldimethylammonium chloride), Poly(melamine-co-formaldehyde), Poly[[6-[(1,1,3,3-tetramethylbutyl)amino]-s-triazine-2,4-diyl]-[(2,2,6,6-tetramethyl-4-piperidyl)imino]-hexamethylene-[(2,2,6,6-tetramethyl-4-piperidyl)imino] and the like.
FILED	Friday, June 15, 2012
APPL NO	14/126565
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/90 (20130101) H01M 4/9091 (20130101) Original (OR) Class H01M 2004/8689 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09502730 — Printed biofuel cells

US 09502730	Wang et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents Of The University Of California (Oakland, California)
INVENTOR(S)	Joseph Wang (San Diego, California); Joshua Ray Windmiller (Del Mar, California); Wenzhao Jia (San Diego, California)
ABSTRACT	Methods, systems, and devices are disclosed for implementing a biofuel cell device for extracting energy from a biofuel. In one aspect, a biofuel cell device includes a substrate, an anode including a catalyst to facilitate the conversion of a fuel in a biological fluid in an oxidative process that releases electrons captured at the anode, thereby extracting energy from the fuel substance, a cathode configured on the substrate adjacent to the anode and separated from the anode by a spacing region, and a load electrically coupled to the anode and cathode via electrical interconnects to obtain the extracted energy as electrical energy.
FILED	Friday, November 30, 2012
APPL NO	14/362100
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Diagnosis; Surgery; Identification A61B 2560/0214 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/926 (20130101) H01M 4/8803 (20130101) H01M 4/8807 (20130101) H01M 4/8832 (20130101) H01M 4/8835 (20130101) H01M 4/8846 (20130101) H01M 4/8853 (20130101) H01M 4/9008 (20130101) H01M 8/004 (20130101) H01M 8/16 (20130101) Original (OR) Class H01M 8/0206 (20130101) H01M 8/0239 (20130101) H01M 8/0245 (20130101) H01M 8/0247 (20130101) H01M 8/1097 (20130101) H01M 8/04208 (20130101) H01M 2250/30 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/18 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/522 (20130101) Y02E 60/527 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/136 (20151101)
VIEW PATENT	@ USPTO: Full Text PDF

09503478 — Policy-based secure communication with automatic key management for industrial control and automation systems

US 09503478	Chernoguzov et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE)
APPLICANT(S)	Honeywell International Inc. (Morristown, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Alexander Chernoguzov (Warrington, Pennsylvania); Thomas R. Markham (Fridley, Minnesota); Harshal S. Haridas (Jamison, Pennsylvania)
ABSTRACT	A method includes generating at least one access vector associated with a specified device in an industrial process control and automation system. The specified device has one of multiple device roles. The at least one access vector is generated based on one or more communication policies defining communications between one or more pairs of devices roles in the industrial process control and automation system, where each pair of device roles includes the device role of the specified device. The method also includes providing the at least one access vector to at least one of the specified device and one or more other devices in the industrial process control and automation system in order to control communications to or from the specified device.
FILED	Thursday, June 19, 2014
APPL NO	14/309251
ART UNIT	2494 — Cryptography and Security
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) G05B 19/0428 (20130101) G05B 19/4185 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/06 (20130101) H04L 63/08 (20130101) H04L 63/10 (20130101) H04L 63/20 (20130101) Original (OR) Class H04L 63/062 (20130101) H04L 63/101 (20130101) H04L 63/104 (20130101) H04L 63/105 (20130101) H04L 67/12 (20130101)
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09504148 — Rapid PCB prototyping by selective adhesion

US 09504148	Hatch et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Kansas City National Security Campus (KCNSC) NNSA Critical Mission Site Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)	HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S)	Jonathan Douglas Hatch (Cleveland, Ohio); Stephen McGarry Hatch (Blue Springs, Missouri)
ABSTRACT	A PCB page blank includes a flexible substrate, a curable adhesive, a conductive layer, and a conductive layer support. The flexible substrate receives an opaque negative circuit pattern thereon. Portions of the curable adhesive not obscured by the circuit pattern may bond to portions of the conductive layer when exposed to light. The bonded portions of the conductive layer shear or tear from non-bonded portions of the conductive layer such that the bonded portions remain with the flexible substrate and the non-bonded portions remain with the conductive layer support when the flexible substrate and the conductive layer support are separated. The flexible substrate and the bonded portions of the conductive layer thus form a PCB prototype with the bonded portions of the conductive layer forming circuit traces of the circuit pattern.
FILED	Wednesday, December 02, 2015
APPL NO	14/957426
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/02 (20130101) H05K 1/0393 (20130101) Original (OR) Class H05K 3/103 (20130101) H05K 3/386 (20130101) H05K 3/389 (20130101) H05K 2201/05 (20130101)
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09504177 — Hermetic electronics package with dual-sided electrical feedthrough configuration

US 09504177	Shah et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Kedar G. Shah (Oakland, California); Satinderpall S. Pannu (Pleasanton, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Kedar G. Shah (Oakland, California); Satinderpall S. Pannu (Pleasanton, California)
ABSTRACT	A hermetic electronics package includes a metal case with opposing first and second open ends, with each end connected to a first feedthrough construction and a second feedthrough construction. Each feedthrough contruction has an electrically insulating substrate and an array of electrically conductive feedthroughs extending therethrough, with the electrically insulating substrates connected to the opposing first and second open ends, respectively, of the metal case so as to form a hermetically sealed enclosure. A set of electronic components are located within the hermetically sealed enclosure and are operably connected to the feedthroughs of the first and second feedthrough constructions so as to electrically communicate outside the package from opposite sides of the package.
FILED	Thursday, June 14, 2012
APPL NO	14/118192
ART UNIT	2848 — Electrical Circuits and Systems
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/04001 (20130101) A61B 5/6861 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3752 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/49827 (20130101) H01L 24/48 (20130101) H01L 2224/48091 (20130101) H01L 2224/48091 (20130101) H01L 2924/00 (20130101) H01L 2924/00014 (20130101) H01L 2924/12042 (20130101) H01L 2924/12042 (20130101) H01L 2924/19107 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 3/26 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/4644 (20130101) H05K 5/069 (20130101) Original (OR) Class H05K 5/0247 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49126 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

National Science Foundation (NSF)

09498221 — Implantable medical devices having double walled microspheres

US 09498221	Kokai et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S)	Lauren E. Kokai (Santa Barbara, California); Kacey Gribbin Marra (Canonsburg, Pennsylvania)
ABSTRACT	An implantable medical device including at least one double-walled microsphere containing an active agent, and a biodegradable polymer layer containing the at least one double-walled microsphere.
FILED	Thursday, March 07, 2013
APPL NO	13/788879
ART UNIT	1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/1128 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/50 (20130101) A61K 9/5031 (20130101) A61K 38/185 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/54 (20130101) A61L 2430/32 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/22 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09498292 — Single site robotic device and related systems and methods

US 09498292	Mondry et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S)	Jack Mondry (Stillwater, Minnesota); Shane Farritor (Lincoln, Nebraska); Eric Markvicka (Ravenna, Nebraska); Thomas Frederick (Omaha, Nebraska); Joseph Bartels (Lincoln, Nebraska)
ABSTRACT	The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various medical devices for in vivo medical procedures.
FILED	Friday, March 15, 2013
APPL NO	13/839422
ART UNIT	3769 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 19/2203 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2034/302 (20160201) A61B 2034/2048 (20160201) A61B 2034/2051 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0084 (20130101)
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09498293 — Automated cell patch clamping method and apparatus

US 09498293	Kodandaramaiah et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) NIH Office of the Director (NIHOD) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	Suhasa Bangalore Kodandaramaiah (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Craig Richard Forest (Atlanta, Georgia)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Suhasa Bangalore Kodandaramaiah (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Craig Richard Forest (Atlanta, Georgia)
ABSTRACT	In an automated method for in vivo multiple cell patch clamping, cell patch clamping devices are automatically moved into position and targeted to multiple corresponding cells. Cell contact is determined by analyzing the temporal series of measured resistance levels at the clamping devices as they are moved. The difference between successive resistance levels is computed and compared to a threshold, which must be exceeded for a minimum number of computations before neuron contact is assumed. Pneumatic control methods are used to achieve cell-attached or gigaseal formation and subsequent cell break-in, leading to whole-cell patch clamp formation. An automated robotic system automatically performs patch clamping in vivo, automatically detecting cells according to the methodology by analyzing the temporal sequence of electrode impedance changes. By continuously monitoring the patching process and rapidly executing actions triggered by specific measurements, the robot can rapidly find neurons in the living brain and establish recordings.
FILED	Wednesday, November 13, 2013
APPL NO	14/079630
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0538 (20130101) A61B 5/04001 (20130101) A61B 5/6885 (20130101) A61B 19/2203 (20130101) Original (OR) Class A61B 34/32 (20160201) A61B 2503/40 (20130101)
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09498759 — Compartmentalized screening by microfluidic control

US 09498759	Griffiths et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Andrew Griffiths (Strasbourg, France); David Weitz (Cambridge, Massachusetts); Keunho Ahn (San Diego, California); Darren R. Link (Lexington, Massachusetts); Jerome Bibette (Paris, France)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Medical Research Council (London, United Kingdom)
INVENTOR(S)	Andrew Griffiths (Strasbourg, France); David Weitz (Cambridge, Massachusetts); Keunho Ahn (San Diego, California); Darren R. Link (Lexington, Massachusetts); Jerome Bibette (Paris, France)
ABSTRACT	The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, comprising the steps of: a) compartmentalizing the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsule; and b) identifying the compound which binds to or modulates the activity of the target; wherein at least one step is performed under microfluidic control. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development.
FILED	Wednesday, October 12, 2005
APPL NO	11/665145
ART UNIT	1677 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 5/0256 (20130101) B01F 5/0646 (20130101) Original (OR) Class B01F 5/0647 (20130101) B01F 5/0655 (20130101) B01F 13/0062 (20130101) B01F 13/0071 (20130101) B01F 13/0076 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00576 (20130101) B01J 2219/00596 (20130101) B01J 2219/00599 (20130101) B01J 2219/00657 (20130101) B01J 2219/00664 (20130101) B01J 2219/00702 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502784 (20130101) B01L 2200/0647 (20130101) B01L 2200/0652 (20130101) B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/0406 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2563/159 (20130101) C12Q 2565/119 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5432 (20130101) G01N 2015/149 (20130101) G01N 2500/10 (20130101)
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09499407 — Carbon and carbon/silicon composite nanostructured materials and casting formation method

US 09499407	Sailor et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Michael J. Sailor (La Jolla, California); Timothy Kelly (San Diego, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Michael J. Sailor (La Jolla, California); Timothy Kelly (San Diego, California)
ABSTRACT	The invention provides nanostructure composite porous silicon and carbon materials, and also provides carbon nanofiber arrays having a photonic response in the form of films or particles. Composite materials or carbon nanofiber arrays of the invention are produced by a templating method of the invention, and the resultant nanomaterials have a predetermined photonic response determined by the pattern in the porous silicon template, which is determined by etching conditions for forming the porous silicon. Example nanostructures include rugate filters, single layer structures and double layer structures. In a preferred method of the invention, a carbon precursor is introduced into the pores of a porous silicon film. Carbon is then formed from the carbon precursor. In a preferred method of the invention, liquid carbon-containing polymer precursor is introduced into the pores of an porous silicon film The precursor is thermally polymerized to form a carbon-containing polymer in the pores of the porous silicon film, which is then thermally carbonized to produce the nano structured composite material. A carbon nanofiber array is obtained by dissolving the porous silicon. A carbon nanofiber array can be maintained as a film in liquid, and particles can be formed by drying the material.
FILED	Thursday, September 29, 2011
APPL NO	13/824125
ART UNIT	1785 — Miscellaneous Articles, Stock Material
CURRENT CPC	Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 1/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/022 (20130101) Original (OR) Class C01B 31/0226 (20130101) C01B 31/0246 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/14 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2918 (20150115) Y10T 428/249994 (20150401)
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09499465 — Synthesis of biobased and substituted terephthalic acids and isophthalic acids

US 09499465	Frost
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	John W. Frost (Okemos, Michigan)
ABSTRACT	Methods for producing bio-terephthalic acid and bio-isophthalic acid are provided. The methods comprise a cycloaddition reaction to produce bio-4-methyl-3-cyclohexene-1-carboxylic acid, and bio-3-methyl-3-cyclohexene-1-carboxylic from bio-isoprene and bio-acrylic acid. An aromatization reaction produces bio-para-toluic acid and bio-meta-toluic acid from the bio-4-methyl-3-cyclohexene-1-carboxylic acid, and bio-3-methyl-3-cyclohexene-1-carboxylic. An oxidation reaction produces the bio-terephthalic acid and iso-phthalic acid from the bio-para-toluic acid and bio-meta-toluic acid.
FILED	Friday, March 14, 2014
APPL NO	14/775149
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 51/265 (20130101) Original (OR) Class C07C 51/265 (20130101) C07C 51/265 (20130101) C07C 51/353 (20130101) C07C 51/353 (20130101) C07C 51/353 (20130101) C07C 51/353 (20130101) C07C 51/377 (20130101) C07C 51/377 (20130101) C07C 61/22 (20130101) C07C 61/29 (20130101) C07C 62/38 (20130101) C07C 63/04 (20130101) C07C 63/24 (20130101) C07C 63/26 (20130101) C07C 2101/16 (20130101) C07C 2102/44 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/183 (20130101)
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09499511 — N-substituted hydroxylamine derivatives with carbon-based leaving groups

US 09499511	Toscano et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	John P. Toscano (Glen Arm, Maryland); Daryl A. Guthrie (Baltimore, Maryland)
ABSTRACT	The disclosed subject matter provides certain N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or development of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy.
FILED	Thursday, October 29, 2015
APPL NO	14/927039
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 231/08 (20130101) C07D 231/22 (20130101) C07D 231/46 (20130101) C07D 239/62 (20130101) C07D 319/06 (20130101) Original (OR) Class
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09499575 — Synthesis of carbohydrate-based surfactants

US 09499575	Pemberton et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	The Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Jeanne E. Pemberton (Tucson, Arizona); Robin L. Polt (Tucson, Arizona); Raina M. Maier (Tucson, Arizona); Clifford S. Coss (Tucson, Arizona)
ABSTRACT	The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate-based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a hydrophobic compound.
FILED	Monday, September 30, 2013
APPL NO	14/041251
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/003 (20130101) C07F 9/94 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 15/04 (20130101) C07H 15/06 (20130101) Original (OR) Class C07H 15/14 (20130101)
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09499592 — Transcription activator-like effectors

US 09499592	Zhang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Energy (DOE) Office of Science (DOE-SC) Office of Science Consolidated Service Center (CSC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Brookline, Massachusetts); Sriram Kosuri (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Feng Zhang (Cambridge, Massachusetts); Le Cong (Brookline, Massachusetts); Sriram Kosuri (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts)
ABSTRACT	Provided herein are compositions, kits and methods useful in the construction of designer transcription activator-like effector (dTALE) polypeptides.
FILED	Thursday, January 19, 2012
APPL NO	13/353662
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 14/195 (20130101) Original (OR) Class C07K 14/4705 (20130101) C07K 2319/00 (20130101) C07K 2319/09 (20130101) C07K 2319/60 (20130101) C07K 2319/80 (20130101)
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09499766 — Nanoparticle compositions and methods for making and using the same

US 09499766	Malshe et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
ASSIGNEE(S)
INVENTOR(S)	Ajay P. Malshe (Springdale, Arkansas); Arpana Verma (Fayetteville, Arkansas)
ABSTRACT	A composition that includes solid lubricant nanoparticles and an organic medium is disclosed. Also disclosed are nanoparticles that include layered materials. A method of producing a nanoparticle by milling layered materials is provided. Also disclosed is a method of making a lubricant, the method including milling layered materials to form nanoparticles and incorporating the nanoparticles into a base to form a lubricant.
FILED	Wednesday, June 19, 2013
APPL NO	13/921640
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 125/22 (20130101) C10M 169/04 (20130101) Original (OR) Class C10M 169/042 (20130101) C10M 171/06 (20130101) C10M 2201/04 (20130101) C10M 2201/06 (20130101) C10M 2201/041 (20130101) C10M 2201/042 (20130101) C10M 2201/061 (20130101) C10M 2201/062 (20130101) C10M 2201/065 (20130101) C10M 2201/066 (20130101) C10M 2201/081 (20130101) C10M 2201/082 (20130101) C10M 2201/084 (20130101) C10M 2201/087 (20130101) C10M 2201/103 (20130101) C10M 2203/0206 (20130101) C10M 2203/1006 (20130101) C10M 2205/163 (20130101) C10M 2207/401 (20130101) C10M 2207/0406 (20130101) C10M 2207/1285 (20130101) C10M 2207/2815 (20130101) C10M 2207/2835 (20130101) C10M 2213/046 (20130101) C10M 2213/062 (20130101) C10M 2215/0813 (20130101) C10M 2223/103 (20130101) C10M 2229/025 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2210/02 (20130101) C10N 2210/03 (20130101) C10N 2210/04 (20130101) C10N 2210/08 (20130101) C10N 2220/082 (20130101) C10N 2230/56 (20130101) C10N 2250/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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09499813 — Systems and methods for amplification and phage display

US 09499813	Derda et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Ratmir Derda (Cambridge, Massachusetts); Sindy K. Y. Tang (Stanford, California); George M. Whitesides (Newton, Massachusetts)
ASSIGNEE(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Ratmir Derda (Cambridge, Massachusetts); Sindy K. Y. Tang (Stanford, California); George M. Whitesides (Newton, Massachusetts)
ABSTRACT	Embodiments of various aspects described herein are directed to amplification of biological entities, for example, for phage display. In one aspect, members of a library of biological entities are encapsulated in separate compartments (e.g., in separate microfluidic droplets) and amplified. For example, by putting members of a phage display library into microfluidic droplets such that no droplet contains more than one member of the library, the library can be amplified without any substantial changes in population distributions, or other artifacts created due to differences in growth rates or amplification between different members of the library. In some cases, the volume of the compartments can be used to control the copy number of a biological entity during amplification. This can be advantageous, for example, in preserving diversity within a library by preventing rapidly amplifying biological entities from outcompeting slowly amplifying biological entities.
FILED	Friday, June 10, 2011
APPL NO	13/702603
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/02 (20130101) C40B 50/06 (20130101)
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09499836 — Fertilization and fruit size

US 09499836	Crawford et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS)
APPLICANT(S)	Brian C. W. Crawford (San Diego, California); Martin F. Yanofsky (San Diego, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Brian C. W. Crawford (San Diego, California); Martin F. Yanofsky (San Diego, California)
ABSTRACT	Plants having modulated expression of a HAF or BEE polypeptide and which modulate aspects of plant fertility, such as parthenocarpy, fertilization efficiency, and/or fruit size, are described. Methods of modulating fertility characteristics in a plant by modulating the expression of a HAF or BEE polypeptide in the plant are also described.
FILED	Thursday, May 31, 2012
APPL NO	14/119426
ART UNIT	1663 — Plants
CURRENT CPC	Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/829 (20130101) C12N 15/8249 (20130101) C12N 15/8261 (20130101) C12N 15/8287 (20130101) Original (OR) Class
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09499853 — Biosensing system with extended lifetime via cofactor recycling

US 09499853	Reardon
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Kenneth F. Reardon (Fort Collins, Colorado)
ASSIGNEE(S)	COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado)
INVENTOR(S)	Kenneth F. Reardon (Fort Collins, Colorado)
ABSTRACT	The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for recycling cofactors.
FILED	Thursday, August 02, 2012
APPL NO	14/236531
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0069 (20130101) C12N 9/0071 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) Original (OR) Class C12Q 1/32 (20130101) Enzymes C12Y 102/01002 (20130101) C12Y 113/00 (20130101) C12Y 114/00 (20130101) C12Y 114/13 (20130101)
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09500186 — High surface area polymer actuator with gas mitigating components

US 09500186	Banister et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Mark Banister (Tucson, Arizona); Raymond Clark (Tucson, Arizona); Erich Coiner (Poway, California); Yordan M. Geronov (Tucson, Arizona); Mark D. McWilliams (San Diego, California); Mark A. Van Veen (Cardiff by the Sea, California)
ASSIGNEE(S)	MEDIPACS, INC. (Tucson, Arizona)
INVENTOR(S)	Mark Banister (Tucson, Arizona); Raymond Clark (Tucson, Arizona); Erich Coiner (Poway, California); Yordan M. Geronov (Tucson, Arizona); Mark D. McWilliams (San Diego, California); Mark A. Van Veen (Cardiff by the Sea, California)
ABSTRACT	A polymer actuator component and a polymer actuator assembly, power supply and method of using the activation are described.
FILED	Monday, January 31, 2011
APPL NO	13/018024
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/005 (20130101) Original (OR) Class
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09500519 — Superconducting single photon detector

US 09500519	Tang et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Hongxing Tang (Orange, Connecticut); Wolfram Pernice (New Haven, Connecticut); Carsten Schuck (New Haven, Connecticut)
ABSTRACT	The present invention provides a device and system for high-efficiency and low-noise detection of single photons within the visible and infrared spectrum. In certain embodiments, the device of the invention can be integrated within photonic circuits to provide on-chip photon detection. The device comprises a traveling wave design comprising a waveguide layer and a superconducting nanowire atop of the waveguide.
FILED	Tuesday, December 03, 2013
APPL NO	14/095516
ART UNIT	2878 — Optics
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/0425 (20130101) Original (OR) Class G01J 2001/442 (20130101) Optical Elements, Systems, or Apparatus G02B 6/0229 (20130101) G02B 6/12004 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/954 (20130101)
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09500540 — Methods and apparatus for monitoring microrolling processes using embedded sensing

US 09500540	Gao et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S)	University of Connecticut (Framington, Connecticut)
INVENTOR(S)	Robert X. Gao (Manchester, Connecticut); Zhaoyan Fan (Willimantic, Connecticut); Jian Cao (Wilmette, Illinois)
ABSTRACT	A method of determining a spatial and temporal pressure distribution profile on an outer surface of a rotating apparatus includes producing one or more pressure indications in response to pressure applied to the outer surface of the rotating apparatus. The producing is carried out by a transducer assembly embedded within the rotating apparatus at a distance d from the outer surface of the rotating apparatus. The method further includes sampling, by an acquisition assembly, the one or more pressure indications from the transducer assembly and storing the sampled one or more pressure indications. The method also includes processing the one or more pressure indications to produce the pressure distribution profile describing the pressure applied to the outer surface.
FILED	Friday, March 14, 2014
APPL NO	14/214058
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/146 (20130101) Original (OR) Class G01L 5/0076 (20130101)
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09500604 — Air slide analyzer system and method

US 09500604	Charette et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	XRSciences LLC (Carlsbad, California)
ASSIGNEE(S)	XRSciences, LLC (Carlsbad, California)
INVENTOR(S)	Colin Charette (Encinitas, California); Tom Atwell (Carlsbad, California); Jacob Lopp (Fort Worth, California); Chaur-Ming Shyu (San Diego, California)
ABSTRACT	Systems and Methods for an air slide analyzer for measuring the elemental content of aerated material traveling by air slide. The air slide analyzer has an analyzer having an entrance opening and an exit opening, and an interior tunnel adapted for aerated material conveyed by an air slide; a radiation detector proximal to the analyzer; a neutron source emitting neutrons into material within the analyzer; and a processor to analyze detected information from the radiation detector, wherein emissions from the material being irradiated with neutrons are detected by the radiation detector and analyzed by the processor to provide elemental information of the material in the analyzer.
FILED	Thursday, April 30, 2015
APPL NO	14/700417
ART UNIT	2884 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/083 (20130101) G01N 23/222 (20130101) Original (OR) Class G01N 2223/071 (20130101) G01N 2223/076 (20130101) G01N 2223/635 (20130101) G01N 2223/0745 (20130101) Measurement of Nuclear or X-radiation G01T 3/02 (20130101)
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09500623 — Synchronization of ion generation with cycling of a discontinuous atmospheric interface

US 09500623	Cooks et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Jason Duncan (Dayton, Indiana); Guangming Huang (West Lafayette, Indiana); Guangtao Li (Carmel, Indiana); Xin Yan (West Lafayette, Indiana); Ewa Sokol (West Lafayette, Indiana); Xin Li (West Lafayette, Indiana)
ABSTRACT	The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.
FILED	Monday, October 14, 2013
APPL NO	14/052815
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/62 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0445 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/24 (20150115)
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09500705 — Integrated circuit providing fault prediction

US 09500705	Balasubramanian et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Raghuraman Balasubramanian (Madison, Wisconsin); Karthikeyan Sankaralingam (Madison, Wisconsin)
ABSTRACT	The prediction of hardware failure is obtained by operating two redundant circuit modules while one circuit module is artificially aged. The output of the two circuit modules is compared and a discrepancy between outputs indicates a projected failure of the aged modules. Aging may be accomplished by one or a combination of lowering operating voltages and re-phasing a sampling clock to reduce slack time both of which provide increased sensitivity to gate delay.
FILED	Wednesday, August 28, 2013
APPL NO	14/012255
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31725 (20130101) Original (OR) Class
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09500717 — Method for small-signal stability assessment of power systems using source side and load side series voltage injection perturbations

US 09500717	Salmani et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S)	Mohamadamin Salmani (Tallahassee, Florida); Chris S. Edrington (Tallahassee, Florida)
ABSTRACT	A novel method for real-time small-signal stability analysis for power electronic-based components in a power system. The method may be used to monitor a power system in real-time by perturbing the source side of an electronic-based component of the power system of about 0.5 to 1 percent of a nominal current of the power system at the source side, and perturbing the load side of the power electronic-based component by varying the voltage at the load side using a series voltage injection. Time-domain results of the simultaneous perturbations may be transferred to frequency-domain results and the stability of the power system may be monitored by obtaining a Nyquist contour and employing Generalized Nyquist Criterion or unit circle criterion.
FILED	Monday, April 18, 2016
APPL NO	15/131679
ART UNIT	2863 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 27/16 (20130101) G01R 31/40 (20130101) Original (OR) Class
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09500948 — Fluorinated photoresist with integrated sensitizer

US 09500948	Wright et al.
FUNDED BY	National Science Foundation (NSF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Orthogonal, Inc. (Rochester, New York)
ASSIGNEE(S)	Orthogonal, Inc. (Rochester, New York)
INVENTOR(S)	Charles Warren Wright (Fairport, New York); Douglas Robert Robello (Webster, New York)
ABSTRACT	A method of patterning a device comprises providing on a device substrate a layer of a fluorinated photopolymer comprising at least three distinct repeating units including a first repeating unit having a fluorine-containing group, a second repeating unit having an acid- or alcohol-forming precursor group, and a third repeating unit having a sensitizing dye. The photopolymer has a total fluorine content in a range of 15 to 60% by weight. The photopolymer layer is exposed to patterned light and contacted with a developing agent to remove a portion of exposed photopolymer layer in accordance with the patterned light, thereby forming a developed structure having a first pattern of photopolymer covering the substrate and a complementary second pattern of uncovered substrate corresponding to the removed portion of photopolymer. The developing agent comprises at least 50% by volume of a fluorinated solvent.
FILED	Friday, May 30, 2014
APPL NO	14/291692
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0045 (20130101) Original (OR) Class G03F 7/0046 (20130101) G03F 7/325 (20130101) G03F 7/0392 (20130101) G03F 7/426 (20130101)
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09500952 — Orthogonal processing of organic materials used in electronic and electrical devices

US 09500952	Ober et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Christopher K. Ober (Ithaca, New York); George Malliaras (Ithaca, New York); Jin-Kyun Lee (Incheon, South Korea); Alexander Zakhidov (McKinney, Texas); Margarita Chatzichristidi (Athens, Greece); Priscilla Dodson (Berkeley, California)
ABSTRACT	An orthogonal process for photolithographic patterning organic structures is disclosed. The disclosed process utilizes fluorinated solvents or supercritical CO₂as the solvent so that the performance of the organic conductors and semiconductors would not be adversely affected by other aggressive solvent. One disclosed method may also utilize a fluorinated photoresist together with the HFE solvent, but other fluorinated solvents can be used. In one embodiment, the fluorinated photoresist is a resorcinarene, but various fluorinated polymer photoresists and fluorinated molecular glass photoresists can be used as well. For example, a copolymer perfluorodecyl methacrylate (FDMA) and 2-nitrobenzyl methacrylate (NBMA) is a suitable orthogonal fluorinated photoresist for use with fluorinated solvents and supercritical carbon dioxide in a photolithography process. The combination of the fluorinated photoresist and the fluorinated solvent provides a robust, orthogonal process that is yet to be achieved by methods or devices known in the art.
FILED	Friday, December 11, 2015
APPL NO	14/966570
ART UNIT	2896 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/16 (20130101) G03F 7/20 (20130101) Original (OR) Class G03F 7/30 (20130101) G03F 7/40 (20130101) G03F 7/0046 (20130101) G03F 7/0048 (20130101) G03F 7/325 (20130101) G03F 7/0392 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0018 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24802 (20150115)
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09501227 — Memory controller for heterogeneous computer

US 09501227	Wang et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Hao Wang (Madison, Wisconsin); Nam Sung Kim (Middleton, Wisconsin)
ABSTRACT	A memory controller for heterogeneous computer processors dynamically adjusts access priorities by the different processors to maximize performance in the execution of a single parallel application program on both processor architectures. In one embodiment, the memory controller predicts sequential memory accesses by the processor having higher memory latency or fewer access requests to lockout the other processor during those sequences for improved implementation of the intended prioritization.
FILED	Thursday, August 21, 2014
APPL NO	14/465126
ART UNIT	2135 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 3/0611 (20130101) Original (OR) Class G06F 3/0659 (20130101) G06F 3/0683 (20130101)
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09501382 — Systems and methods of detecting power bugs

US 09501382	Hu et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S)	Yu Charlie Hu (West Lafayette, Indiana); Abhilash Jindal (West Lafayette, Indiana); Samuel Midkiff (West Lafayette, Indiana); Abhinav Pathak (San Jose, California)
ABSTRACT	Embodiments of the present invention provide a system and methods for detecting power bugs. In one embodiment, a computer-implemented method for analyzing a computer code includes generating a control flow graph for at least a portion of the computer code at a processor. The method further includes identifying power bugs by traversing the control flow graph if the control flow graph exits without performing a function call to deactivate power to any component of a device configured to execute computer executable instructions based on the computer code after performing a function call to activate power.
FILED	Tuesday, June 24, 2014
APPL NO	14/313890
ART UNIT	2192 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 8/20 (20130101) G06F 8/433 (20130101) G06F 11/3466 (20130101) G06F 11/3604 (20130101) Original (OR) Class
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09501469 — Analogy finder

US 09501469	McCaffrey
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Anthony McCaffrey (West Brookfield, Massachusetts)
ABSTRACT	A user provides a query that includes at least two of a subject, a predicate, and an object. A computer system identifies synonyms of one or more of the subject, predicate, and object, and forms new queries from the identified synonyms. The system searches a dataset using the new queries, and possibly also using the user-provided query, to produce search results. The system may process the search results, such as by filtering and/or sorting them. The system provides output representing the search results to the user. The user may use the search result output to identify answers that are analogous to answers to the query originally provided by the user.
FILED	Thursday, November 21, 2013
APPL NO	14/085897
ART UNIT	2658 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Electric Digital Data Processing G06F 17/2775 (20130101) G06F 17/2795 (20130101) Original (OR) Class G06F 17/30654 (20130101)
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09501509 — Throwaway spatial index structure for dynamic point data

US 09501509	Akdogan et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Afsin Akdogan (Los Angeles, California); Cyrus Shahabi (Irvine, California); Ugur Demiryurek (Redondo Beach, California)
ASSIGNEE(S)	UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S)	Afsin Akdogan (Los Angeles, California); Cyrus Shahabi (Irvine, California); Ugur Demiryurek (Redondo Beach, California)
ABSTRACT	The present disclosure relates to a short-lived throwaway index structure for generating an index from scratch in a short period of time rather than updating an index with every location change of moving objects. Rapid index construction results from the generation of Voronoi diagrams in parallel using multiple cloud servers simultaneously.
FILED	Wednesday, September 10, 2014
APPL NO	14/482805
ART UNIT	2156 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/30241 (20130101) G06F 17/30327 (20130101) Original (OR) Class
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09501639 — Methods, systems, and media for baiting inside attackers

US 09501639	Stolfo et al.
FUNDED BY	Department of Homeland Security (DHS) Institute for Information Infrastructure Protection (I3P) Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Salvatore J. Stolfo (Ridgewood, New Jersey); Angelos D. Keromytis (New York, New York); Brian M. Bowen (New York, New York); Shlomo Hershkop (Brooklyn, New York); Vasileios P. Kemerlis (New York, New York); Pratap V. Prabhu (New York, New York); Malek Ben Salem (Wappingers Falls, New York)
ABSTRACT	Methods, systems, and media for providing trap-based defenses are provided. In accordance with some embodiments, a method for providing trap-based defenses is provided, the method comprising: generating decoy information based at least in part on actual information in a computing environment, wherein the decoy information is generated to comply with one or more document properties; embedding a beacon into the decoy information; and inserting the decoy information with the embedded beacon into the computing environment, wherein the embedded beacon provides a first indication that the decoy information has been accessed by an attacker and wherein the embedded beacon provides a second indication that differentiates between the decoy information and the actual information.
FILED	Monday, March 09, 2015
APPL NO	14/642401
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/554 (20130101) Original (OR) Class G06F 21/566 (20130101) G06F 2221/034 (20130101) G06F 2221/2123 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1466 (20130101)
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09501779 — Automated thumbnail selection for online video

US 09501779	Lebrecht et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S)	Sophie Lebrecht (Providence, Rhode Island); Michael Jay Tarr (Pittsburgh, Pennsylvania); Deborah Johnson (San Bruno, California); Mark Desnoyer (San Francisco, California); Sunil Mallya Kasaragod (San Francisco, California)
ABSTRACT	Access is provided to optimal thumbnails that are extracted from a stream of video. Using a processing device configured with a model that incorporates preferences generated by the brain and behavior from the perception of visual images, the optimal thumbnail(s) for a given video is/are selected, stored and/or displayed.
FILED	Thursday, November 14, 2013
APPL NO	14/442759
ART UNIT	2427 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/015 (20130101) G06F 2203/011 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/02 (20130101) G06Q 30/0201 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 21/252 (20130101) H04N 21/4662 (20130101) H04N 21/4667 (20130101) H04N 21/44218 (20130101)
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09502711 — Fabrication of biscrolled fiber using carbon nanotube sheet

US 09502711	Fang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Asian Office of Aerospace Research and Development (AOARD) Department of the Navy (DON) Office of Naval Research (ONR) Multidisciplinary University Research Initiative (MURI) Non-Profit Organization (NPO) Robert A. Welch Foundation National Science Foundation (NSF)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Shaoli Fang (Richardson, Texas); Marcio Dias Lima (Richardson, Texas); Xavier N. Lepro-Chavez (Richardson, Texas); Javier Carretero-Gonzalez (Dallas, Texas); Elizabeth Castillo-Martinez (Dallas, Texas); Raquel Ovalle-Robles (Sachse, Texas); Carter Sebastian Haines (Murphy, Texas); David Michael Novitski (Richardson, Texas); Mohammad H. Haque (Dallas, Texas); Chihye Lewis-Azad (Dallas, Texas); Mikhail Kozlov (Dallas, Texas); Anvar A. Zakhidov (McKinney, Texas); Ray H. Baughman (Dallas, Texas)
ABSTRACT	Fabrication of yarns or other shaped articles from materials in powder form (or nanoparticles or nanofibers) using carbon nanotube/nanofiber sheet as a platform (template). This includes methods for fabricating biscrolled yarns using carbon nanotube/nanofiber sheets and biscrolled fibers fabricated thereby.
FILED	Monday, December 14, 2015
APPL NO	14/967940
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/7007 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) A61L 17/04 (20130101) A61L 31/16 (20130101) A61L 31/024 (20130101) A61L 2300/108 (20130101) A61L 2300/414 (20130101) A61L 2300/418 (20130101) A61L 2400/12 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 21/063 (20130101) B01J 21/185 (20130101) B01J 23/42 (20130101) B01J 35/004 (20130101) B01J 35/0006 (20130101) B01J 35/06 (20130101) B01J 37/0215 (20130101) B01J 37/0238 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 3/12 (20130101) B05D 5/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/04 (20130101) C23C 14/58 (20130101) C23C 16/04 (20130101) C23C 16/56 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/16 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) Original (OR) Class H01M 4/96 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/0402 (20130101) H01M 4/587 (20130101) H01M 4/1391 (20130101) H01M 4/1393 (20130101) H01M 4/5825 (20130101) H01M 8/00 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Y02E 60/122 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2918 (20150115) Y10T 428/2929 (20150115)
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09502730 — Printed biofuel cells

US 09502730	Wang et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents Of The University Of California (Oakland, California)
INVENTOR(S)	Joseph Wang (San Diego, California); Joshua Ray Windmiller (Del Mar, California); Wenzhao Jia (San Diego, California)
ABSTRACT	Methods, systems, and devices are disclosed for implementing a biofuel cell device for extracting energy from a biofuel. In one aspect, a biofuel cell device includes a substrate, an anode including a catalyst to facilitate the conversion of a fuel in a biological fluid in an oxidative process that releases electrons captured at the anode, thereby extracting energy from the fuel substance, a cathode configured on the substrate adjacent to the anode and separated from the anode by a spacing region, and a load electrically coupled to the anode and cathode via electrical interconnects to obtain the extracted energy as electrical energy.
FILED	Friday, November 30, 2012
APPL NO	14/362100
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Diagnosis; Surgery; Identification A61B 2560/0214 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/926 (20130101) H01M 4/8803 (20130101) H01M 4/8807 (20130101) H01M 4/8832 (20130101) H01M 4/8835 (20130101) H01M 4/8846 (20130101) H01M 4/8853 (20130101) H01M 4/9008 (20130101) H01M 8/004 (20130101) H01M 8/16 (20130101) Original (OR) Class H01M 8/0206 (20130101) H01M 8/0239 (20130101) H01M 8/0245 (20130101) H01M 8/0247 (20130101) H01M 8/1097 (20130101) H01M 8/04208 (20130101) H01M 2250/30 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 90/18 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/522 (20130101) Y02E 60/527 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/136 (20151101)
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09503126 — ECC polar coding and list decoding methods and codecs

US 09503126	Vardy et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Alexander Vardy (Escondido, California); Ido Tal (San Diego, California)
ABSTRACT	A method of decoding data encoded with a polar code and devices that encode data with a polar code. A received word of polar encoded data is decoded following several distinct decoding paths to generate a list of codeword candidates. The decoding paths are successively duplicated and selectively pruned to generate a list of potential decoding paths. A single decoding path among the list of potential decoding paths is selected as the output and a single candidate codeword is thereby identified. In another preferred embodiment, the polar encoded data includes redundancy values in its unfrozen bits. The redundancy values aid the selection of the single decoding path. A preferred device of the invention is a cellular network device, (e.g., a handset) that conducts decoding in accordance with the methods of the invention.
FILED	Wednesday, July 10, 2013
APPL NO	13/938609
ART UNIT	2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Coding; Decoding; Code Conversion in General H03M 13/09 (20130101) H03M 13/13 (20130101) Original (OR) Class H03M 13/451 (20130101)
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09504150 — Printed electronics

US 09504150	Crain et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)	The Trustees of Princeton University (Princeton, New Jersey); Vorbeck Materials Corporation (Jessup, Maryland)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); VORBECK MATERIALS CORPORATION (Jessup, Maryland)
INVENTOR(S)	John M. Crain (Washington, District of Columbia); John S. Lettow (Washington, District of Columbia); Ilhan A. Aksay (Princeton, New Jersey); Sibel Korkut (Princeton, New Jersey); Katherine S. Chiang (Princeton, New Jersey); Chuan-Hua Chen (Princeton, New Jersey); Robert K. Prud'Homme (Princeton, New Jersey)
ABSTRACT	Printed electronic device comprising a substrate onto at least one surface of which has been applied a layer of an electrically conductive ink comprising functionalized graphene sheets and at least one binder. A method of preparing printed electronic devices is further disclosed.
FILED	Friday, June 26, 2015
APPL NO	14/751418
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/02 (20130101) C01P 2006/12 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/46 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/125 (20130101) C09D 7/1291 (20130101) C09D 11/52 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) Original (OR) Class H05K 1/095 (20130101) H05K 3/12 (20130101) H05K 3/0091 (20130101) H05K 2201/0323 (20130101)
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National Aeronautics and Space Administration (NASA)

09498292 — Single site robotic device and related systems and methods

US 09498292	Mondry et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S)	Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S)	Jack Mondry (Stillwater, Minnesota); Shane Farritor (Lincoln, Nebraska); Eric Markvicka (Ravenna, Nebraska); Thomas Frederick (Omaha, Nebraska); Joseph Bartels (Lincoln, Nebraska)
ABSTRACT	The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various medical devices for in vivo medical procedures.
FILED	Friday, March 15, 2013
APPL NO	13/839422
ART UNIT	3769 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 19/2203 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 90/361 (20160201) A61B 2017/2906 (20130101) A61B 2034/302 (20160201) A61B 2034/2048 (20160201) A61B 2034/2051 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0084 (20130101)
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09498651 — Methods of soft tissue emulsification using a mechanism of ultrasonic atomization inside gas or vapor cavities and associated systems and devices

US 09498651	Sapozhnikov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Aeronautics and Space Administration (NASA) National Space Biomedical Research Institute (NSBRI)
APPLICANT(S)	Oleg A. Sapozhnikov (Seattle, Washington); Michael R. Bailey (Seattle, Washington); Lawrence A. Crum (Bellevue, Washington); Tatiana D. Khokhlova (Seattle, Washington); Vera A. Khokhlova (Seattle, Washington); Julianna C. Simon (Kenmore, Washington); Yak-Nam Wang (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Oleg A. Sapozhnikov (Seattle, Washington); Michael R. Bailey (Seattle, Washington); Lawrence A. Crum (Bellevue, Washington); Tatiana D. Khokhlova (Seattle, Washington); Vera A. Khokhlova (Seattle, Washington); Julianna C. Simon (Kenmore, Washington); Yak-Nam Wang (Seattle, Washington)
ABSTRACT	The present technology is directed to methods of soft tissue emulsification using a mechanism of ultrasonic atomization inside gas or vapor cavities, and associated systems and devices. In several embodiments, for example, a method of non-invasively treating tissue includes pulsing ultrasound energy from the ultrasound source toward the target site in tissue. The ultrasound source is configured to emit high intensity focused ultrasound (HIFU) waves. The target site comprises a pressure-release interface of a gas or vapor cavity located within the tissue. The method continues by generating shock waves in the tissue to induce a lesion in the tissue at the target site. The method additionally includes characterizing the lesion based on a degree of at least one of a mechanical or thermal ablation of the tissue.
FILED	Wednesday, April 11, 2012
APPL NO	13/444466
ART UNIT	3737 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) Original (OR) Class A61N 2007/0039 (20130101)
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09499882 — Strain-detecting composite materials

US 09499882	Wallace et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Terryl A. Wallace (Yorktown, Virginia); Stephen W. Smith (Newport News, Virginia); Robert S. Piascik (Williamsburg, Virginia); Michael R. Horne (Yorktown, Virginia); Peter L. Messick (Poquoson, Virginia); Joel A. Alexa (Hampton, Virginia); Edward H. Glaessgen (Yorktown, Virginia); Benjamin T. Hailer (Rome, New York)
ASSIGNEE(S)	UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (Washington, District of Columbia)
INVENTOR(S)	Terryl A. Wallace (Yorktown, Virginia); Stephen W. Smith (Newport News, Virginia); Robert S. Piascik (Williamsburg, Virginia); Michael R. Horne (Yorktown, Virginia); Peter L. Messick (Poquoson, Virginia); Joel A. Alexa (Hampton, Virginia); Edward H. Glaessgen (Yorktown, Virginia); Benjamin T. Hailer (Rome, New York)
ABSTRACT	A composite material includes a structural material and a shape-memory alloy embedded in the structural material. The shape-memory alloy changes crystallographic phase from austenite to martensite in response to a predefined critical macroscopic average strain of the composite material. In a second embodiment, the composite material includes a plurality of particles of a ferromagnetic shape-memory alloy embedded in the structural material. The ferromagnetic shape-memory alloy changes crystallographic phase from austenite to martensite and changes magnetic phase in response to the predefined critical macroscopic average strain of the composite material. A method of forming a composite material for sensing the predefined critical macroscopic average strain includes providing the shape-memory alloy having an austenite crystallographic phase, changing a size and shape of the shape-memory alloy to thereby form a plurality of particles, and combining the structural material and the particles at a temperature of from about 100-700° C. to form the composite material.
FILED	Monday, January 11, 2010
APPL NO	12/685280
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/14 (20130101) B22F 3/18 (20130101) B22F 5/006 (20130101) B22F 2201/20 (20130101) B22F 2998/00 (20130101) B22F 2998/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Alloys C22C 1/0416 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/12132 (20150115)
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09502229 — Ultra-compact plasma spectrometer

US 09502229	Scime et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	West Virginia University (Morgantown, West Virginia); Advanced Research Corporation (White Bear Lake, Minnesota)
ASSIGNEE(S)	WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia); ADVANCED RESEARCH CORPORATION (White Bear Lake, Minnesota)
INVENTOR(S)	Earl Scime (Morgantown, West Virginia); Amy M. Keesee (Bridgeport, West Virginia); Drew B. Elliot (Morgantown, West Virginia); Matthew Phillip Dugas (North Oaks, Minnesota); Steven Brian Ellison (Woodbury, Minnesota); Joseph Christopher David Tersteeg (Columbia Heights, Minnesota)
ABSTRACT	Various examples are provided for collimator assemblies and/or energy analyzer arrays of plasma spectrometers. In one example, among others, an ultra-compact plasma spectrometer includes a collimator assembly; an energy analyzer array that receives charged particles from the collimator; and a detector plate that detects charged particles exiting the energy analyzer array. The energy analyzer array can include a plurality of analyzer plates having distinct energy channels. In another example, a method includes bonding a stack of analyzer plates to form an energy analyzer array, affixing a collimator assembly to the entrance surface of the energy analyzer array, and affixing an array of detectors to the exit surface of the energy analyzer array. The analyzer plates include energy analyzer bands extending from the entrance surface to the exit surface. The aperture arrays and the detectors can align with the energy analyzer bands.
FILED	Tuesday, April 21, 2015
APPL NO	14/691685
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/48 (20130101) Original (OR) Class
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09504150 — Printed electronics

US 09504150	Crain et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)	The Trustees of Princeton University (Princeton, New Jersey); Vorbeck Materials Corporation (Jessup, Maryland)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); VORBECK MATERIALS CORPORATION (Jessup, Maryland)
INVENTOR(S)	John M. Crain (Washington, District of Columbia); John S. Lettow (Washington, District of Columbia); Ilhan A. Aksay (Princeton, New Jersey); Sibel Korkut (Princeton, New Jersey); Katherine S. Chiang (Princeton, New Jersey); Chuan-Hua Chen (Princeton, New Jersey); Robert K. Prud'Homme (Princeton, New Jersey)
ABSTRACT	Printed electronic device comprising a substrate onto at least one surface of which has been applied a layer of an electrically conductive ink comprising functionalized graphene sheets and at least one binder. A method of preparing printed electronic devices is further disclosed.
FILED	Friday, June 26, 2015
APPL NO	14/751418
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/02 (20130101) C01P 2006/12 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/46 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/125 (20130101) C09D 7/1291 (20130101) C09D 11/52 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) Original (OR) Class H05K 1/095 (20130101) H05K 3/12 (20130101) H05K 3/0091 (20130101) H05K 2201/0323 (20130101)
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Department of Commerce (DOC)

09499686 — Bacterial cellulose based ‘green’ composites

US 09499686	Netravali et al.
FUNDED BY	Department of Commerce (DOC) National Textile Center (NTC)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Anil N. Netravali (Ithaca, New York); Kaiyan Qiu (Ithaca, New York)
ABSTRACT	‘Green’ composites are fabricated using resins, such as soy-based resins, and reinforced with crystalline high strength bacterial cellulose (BC) fibers. Bacterial cellulose is produced by providing a bacterial cellulose-producing bacterium such as Acetobacter xylinum; providing an inexpensive bacteria nutritional medium; culturing the bacterium in the bacteria nutritional medium under conditions to produce bacterial cellulose; and isolating bacterial cellulose produced by cultured bacteria from the bacteria nutritional medium. The bacteria nutritional medium comprises an inexpensive carbon source that is a plant-based seed extract. The seed extract is derived from a plant-based seed comprising soluble sugars.
FILED	Thursday, September 19, 2013
APPL NO	14/031314
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Compositions of Macromolecular Compounds C08L 1/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101)
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09500610 — Systems and methods for controlling temperature of small volumes

US 09500610	Kasianowicz et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	National Institute of Standards and Technology (Gaithersburg, Maryland)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Washington, District of Columbia)
INVENTOR(S)	John J. Kasianowicz (Gaithersburg, Maryland); Joseph E. Reiner (Fredericksburg, Virginia); Arvind K. Balijepalli (Gaithersburg, Maryland); Joseph W. Robertson (Gaithersburg, Maryland); Daniel L. Burden (Wheaton, Illinois); Lisa Burden (Wheaton, Illinois)
ABSTRACT	Systems and methods for controlling the temperature of small volumes such as yoctoliter volumes, are described. The systems include one or more plasmonic nanostructures attached at or near a nanopore. Upon excitation of the plasmonic nanostructures, such as for example by exposure to laser light, the nanoparticles are rapidly heated thereby causing a change in the ionic conductance along the nanopore. The temperature change is determined from the ionic conductance. These temperature changes can be used to control rapid thermodynamic changes in molecular analytes as they interact with the nanopore.
FILED	Wednesday, November 06, 2013
APPL NO	14/073126
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/16 (20130101) G01K 2211/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/00 (20130101) Original (OR) Class
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09503085 — Exclusive-OR gate using magneto-electric tunnel junctions

US 09503085	Bird et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	The Research Foundation for the State University of New York (Amherst, New York); The Board of Regents of The University of Texas System (Austin, Texas)
ASSIGNEE(S)	The Research Foundation for the State University of New York (Amherst, New York); Board of Regents, the University of Texas System (Austin, Texas)
INVENTOR(S)	Jonathan Paul Bird (Buffalo, New York); Andrew Marshall (Dallas, Texas)
ABSTRACT	A magneto-electric (ME) magnetic tunnel junction (MTJ) Exclusive-OR (XOR) gate is provided. The ME MTJ XOR gate includes an insulator separating a top ferromagnetic (FM) layer and a bottom FM layer, a top ME layer on the top FM layer, and a bottom ME layer on the bottom FM layer. The ME MTJ XOR gate also includes a top electrode coupled to the top ME layer and a bottom electrode coupled to the bottom ME layer where a voltage between the top electrode and the top FM layer is a first input, a voltage between the bottom electrode and the bottom FM layer is a second input, and a resistance between the top FM layer and the bottom FM layer is indicative of the XOR of the first input and the second input. The ME MTJ XOR has reduced energy consumption, smaller area, faster switching times, and is non-volatile.
FILED	Wednesday, September 30, 2015
APPL NO	14/871199
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Static Stores G11C 11/161 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/08 (20130101) Pulse Technique H03K 19/0008 (20130101) Original (OR) Class H03K 19/16 (20130101) H03K 19/21 (20130101)
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Small Business Administration (SBA)

09498470 — Antiviral drugs for treatment of arenavirus infection

US 09498470	Dai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	KINETA FOUR, LLC (Seattle, Washington)
ASSIGNEE(S)	Kineta Four, LLC (Seattle, Washington)
INVENTOR(S)	Dongcheng Dai (Corvallis, Oregon); James R. Burgeson (Albany, Oregon); Sean M. Amberg (Corvallis, Oregon); Dennis E. Hruby (Albany, Oregon)
ABSTRACT	Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever.
FILED	Thursday, February 14, 2013
APPL NO	14/379028
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/437 (20130101) A61K 31/4184 (20130101) A61K 31/4439 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 235/06 (20130101) C07D 401/04 (20130101) C07D 471/04 (20130101)
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09499602 — Non-hemolytic LLO fusion proteins and methods of utilizing same

US 09499602	Paterson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Advaxis, Inc. (Princeton, New Jersey)
ASSIGNEE(S)	ADVAXIS, INC. (Princeton, New Jersey); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S)	Yvonne Paterson (Philadelphia, Pennsylvania); Paulo MaCiag (Long Grove, Illinois)
ABSTRACT	The present invention provides recombinant proteins or peptides comprising a mutated listeriolysin O (LLO) protein or fragment thereof, comprising a substitution or internal deletion of the cholesterol-binding domain or a portion thereof, fusion proteins or peptides comprising same, nucleotide molecules encoding same, and vaccine vectors comprising or encoding same. The present invention also provides methods of utilizing recombinant proteins, peptides, nucleotide molecules, and vaccine vectors of the present invention to induce an immune response to a peptide of interest.
FILED	Wednesday, February 12, 2014
APPL NO	14/163269
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/0208 (20130101) A61K 39/385 (20130101) A61K 2039/53 (20130101) A61K 2039/55522 (20130101) Peptides C07K 14/195 (20130101) C07K 14/705 (20130101) Original (OR) Class C07K 16/00 (20130101) C07K 2317/56 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101)
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09500948 — Fluorinated photoresist with integrated sensitizer

US 09500948	Wright et al.
FUNDED BY	National Science Foundation (NSF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Orthogonal, Inc. (Rochester, New York)
ASSIGNEE(S)	Orthogonal, Inc. (Rochester, New York)
INVENTOR(S)	Charles Warren Wright (Fairport, New York); Douglas Robert Robello (Webster, New York)
ABSTRACT	A method of patterning a device comprises providing on a device substrate a layer of a fluorinated photopolymer comprising at least three distinct repeating units including a first repeating unit having a fluorine-containing group, a second repeating unit having an acid- or alcohol-forming precursor group, and a third repeating unit having a sensitizing dye. The photopolymer has a total fluorine content in a range of 15 to 60% by weight. The photopolymer layer is exposed to patterned light and contacted with a developing agent to remove a portion of exposed photopolymer layer in accordance with the patterned light, thereby forming a developed structure having a first pattern of photopolymer covering the substrate and a complementary second pattern of uncovered substrate corresponding to the removed portion of photopolymer. The developing agent comprises at least 50% by volume of a fluorinated solvent.
FILED	Friday, May 30, 2014
APPL NO	14/291692
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0045 (20130101) Original (OR) Class G03F 7/0046 (20130101) G03F 7/325 (20130101) G03F 7/0392 (20130101) G03F 7/426 (20130101)
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U.S. State Government

09499608 — Bispecific monoclonal antibody therapeutics against West Nile virus with improved CNS penetration

US 09499608	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) U.S. State Government State of Arizona
APPLICANT(S)	Qiang Chen (Scottsdale, Arizona); Huafang Lai (Scottsdale, Arizona); Junyun He (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Qiang Chen (Scottsdale, Arizona); Huafang Lai (Scottsdale, Arizona); Junyun He (Scottsdale, Arizona)
ABSTRACT	The plant-based production of a therapeutic antibody against West Nile Virus is disclosed.
FILED	Wednesday, June 06, 2012
APPL NO	14/124173
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/46 (20130101) C07K 16/1081 (20130101) C07K 16/2869 (20130101) C07K 16/2881 (20130101) C07K 19/00 (20130101) C07K 2317/13 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/41 (20130101) C07K 2317/64 (20130101) C07K 2317/66 (20130101) C07K 2317/76 (20130101) C07K 2317/90 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2317/734 (20130101)
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09499845 — Genetically engineered microorganisms that metabolize xylose

US 09499845	Chua et al.
FUNDED BY	U.S. State Government State of California California Energy Commission (CEC)
APPLICANT(S)	TerraVia Holdings, Inc. (South San Francisco, California)
ASSIGNEE(S)	TerraVia Holdings, Inc. (South San Francisco, California)
INVENTOR(S)	Penelope Chua (San Francisco, California); Aravind Somanchi (Redwood City, California)
ABSTRACT	The invention provides methods of cultivating oil-bearing microbes using xylose as a fixed carbon source. Also provided are microorganisms that have been genetically engineered to metabolize xylose as a fixed carbon source allowing them to convert xylose into oils. Particular advantages of the processes provided herein include production of oils rather than alcohols through the microbial fermentation processes utilizing xylose.
FILED	Monday, September 01, 2014
APPL NO	14/474238
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 1/22 (20130101) C12N 15/52 (20130101) C12N 15/8246 (20130101) C12N 15/8247 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/64 (20130101) C12P 7/649 (20130101) C12P 7/6463 (20130101) Original (OR) Class C12P 2203/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/13 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/678 (20130101)
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09501710 — Systems, methods, and media for identifying object characteristics based on fixation points

US 09501710	Karam et al.
FUNDED BY	U.S. State Government State of Arizona
APPLICANT(S)	Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Lina Karam (Scottsdale, Arizona); Samuel Dodge (Scottsdale, Arizona)
ABSTRACT	Systems, methods, and media for optical recognition are provided. In some embodiments, systems for optical recognition are provided, the systems comprising: at least one hardware processor that: identifies a plurality of fixation points in optically detected data; identifies features of the plurality of fixation points; and identifies one or more characteristics of an object represented in the optically detected data. In some embodiments, methods for optical recognition are provided, the methods comprising: identifying a plurality of fixation points in optically detected data using a hardware processor; identifying features of the plurality of fixation points using the hardware processor; and identifying one or more characteristics of an object represented in the optically detected data using the hardware processor. In some embodiments, non-transitory computer-readable media containing computer-executable instructions that, when executed by a hardware processor, cause the processor to perform these methods for optical recognition are provided.
FILED	Monday, July 01, 2013
APPL NO	13/932969
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0061 (20130101) G06K 9/4604 (20130101) Original (OR) Class G06K 9/4671 (20130101)
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Department of Transportation (USDOT)

09498843 — System for preventing the formation of martensite in metals joining applications

US 09498843	Workman
FUNDED BY	Department of Transportation (USDOT) Federal Railroad Administration (FRA)
APPLICANT(S)	EDISON WELDING INSTITUTE, INC. (Columbus, Ohio)
ASSIGNEE(S)	Edison Welding Institute, Inc. (Columbus, Ohio)
INVENTOR(S)	David P. Workman (Dublin, Ohio)
ABSTRACT	A method for joining materials such as metal alloys that includes a first component, wherein the first component includes a first alloy having a known austenization temperature below which martensite forms when the component is heated and then cooled at a predetermined rate of cooling; a second component, wherein the second component includes a second alloy; and a welding apparatus operative to create a weld between the first and second components without crossing the austenization temperature of the first alloy.
FILED	Tuesday, December 09, 2014
APPL NO	14/564598
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/129 (20130101) B23K 20/227 (20130101) Original (OR) Class B23K 20/1205 (20130101) B23K 2201/26 (20130101)
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09499439 — Highly dispersed carbon nanotube-reinforced cement-based materials

US 09499439	Shah et al.
FUNDED BY	Department of Transportation (USDOT)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Surendra P. Shah (Evanston, Illinois); Maria Konsta (Wilmette, Illinois); Zoi S. Metaxa (Evanston, Illinois)
ABSTRACT	A composite cement material is prepared from cement material and carbon nanotubes, wherein the carbon nanotubes are present from about 0.02 wt % to about 0.10 wt % based on weight of cement material. The process for preparing such cement compositions includes sonicating a mixture of a surfactant, water, and carbon nanotubes; and blending the dispersion and the cement material to form a cementitious paste. The process may also include curing the cementitious paste. The composite cement materials are useful in a variety of cement applications where a reduction in nanoscale flaws and fractures is desired.
FILED	Friday, September 04, 2015
APPL NO	14/846037
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 28/04 (20130101) Original (OR) Class
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Central Intelligence Agency (CIA)

09502638 — Method of manufacturing flexible piezoelectric structures

US 09502638	McAlpine et al.
FUNDED BY	Central Intelligence Agency (CIA)
APPLICANT(S)	Michael C. McAlpine (Lawrenceville, New Jersey); Yi Qi (Plainsboro, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Michael C. McAlpine (Lawrenceville, New Jersey); Yi Qi (Plainsboro, New Jersey)
ABSTRACT	A method of making a flexible piezoelectric structure is disclosed. A piezoelectric film is deposited by film deposition on a planar substrate. A biocompatible flexible substrate is contacted with the piezoelectric film. The piezoelectric film and biocompatible flexible substrate are separated from the planar substrate, and the piezoelectric film remaining is attached to the biocompatible flexible substrate.
FILED	Friday, August 03, 2012
APPL NO	13/566738
ART UNIT	3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0408 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 51/1282 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76251 (20130101) H01L 21/76259 (20130101) H01L 41/314 (20130101) Original (OR) Class H01L 41/0533 (20130101) H01L 41/0805 (20130101) H01L 41/0986 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/42 (20150115) Y10T 29/49124 (20150115)
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Department of Agriculture (USDA)

09499444 — Alkyl ester polystyrene blends for use in concrete

US 09499444	Tao et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Bernard Y. Tao (Lafayette, Indiana); William Jason Weiss (West Lafayette, Indiana); Samia Mohtar (West Lafayette, Indiana); Alva Peled (West Lafayette, Indiana); Kevin C. Coates (Huntington Beach, California)
ABSTRACT	A method of treating porous material, such as cement or concrete. In this method, fatty acid alkyl esters having 16 to 22 carbon atoms are provided. Polystyrene is dissolved in the fatty acid alkyl esters to thereby form a blend composition. The blend composition is then applied to a cementitious material, which effectively seals the cementitious material and protects it. In another embodiment, a cementitious material prepared in accordance with the method just described is disclosed.
FILED	Thursday, January 15, 2015
APPL NO	14/597978
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 24/085 (20130101) C04B 24/085 (20130101) C04B 24/085 (20130101) C04B 24/2676 (20130101) C04B 24/2676 (20130101) C04B 24/2676 (20130101) C04B 28/02 (20130101) C04B 28/02 (20130101) C04B 28/02 (20130101) C04B 40/0039 (20130101) C04B 40/0039 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/52 (20130101) C04B 41/52 (20130101) C04B 41/52 (20130101) C04B 41/63 (20130101) C04B 41/4572 (20130101) C04B 41/4574 (20130101) C04B 41/4853 (20130101) C04B 41/4876 (20130101) Original (OR) Class C04B 41/4876 (20130101) C04B 2111/27 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/103 (20130101) C08K 5/103 (20130101) Compositions of Macromolecular Compounds C08L 25/06 (20130101)
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Department of Homeland Security (DHS)

09501639 — Methods, systems, and media for baiting inside attackers

US 09501639	Stolfo et al.
FUNDED BY	Department of Homeland Security (DHS) Institute for Information Infrastructure Protection (I3P) Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Salvatore J. Stolfo (Ridgewood, New Jersey); Angelos D. Keromytis (New York, New York); Brian M. Bowen (New York, New York); Shlomo Hershkop (Brooklyn, New York); Vasileios P. Kemerlis (New York, New York); Pratap V. Prabhu (New York, New York); Malek Ben Salem (Wappingers Falls, New York)
ABSTRACT	Methods, systems, and media for providing trap-based defenses are provided. In accordance with some embodiments, a method for providing trap-based defenses is provided, the method comprising: generating decoy information based at least in part on actual information in a computing environment, wherein the decoy information is generated to comply with one or more document properties; embedding a beacon into the decoy information; and inserting the decoy information with the embedded beacon into the computing environment, wherein the embedded beacon provides a first indication that the decoy information has been accessed by an attacker and wherein the embedded beacon provides a second indication that differentiates between the decoy information and the actual information.
FILED	Monday, March 09, 2015
APPL NO	14/642401
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/554 (20130101) Original (OR) Class G06F 21/566 (20130101) G06F 2221/034 (20130101) G06F 2221/2123 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1466 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

RE046211 — Delivery system using MAB 3E10 and mutants and/or functional fragments thereof

US RE46211	Weisbart
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Richard Weisbart (Los Angeles, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs Office of the General Counsel (Washington, District of Columbia)
INVENTOR(S)	Richard Weisbart (Los Angeles, California)
ABSTRACT	A monoclonal antibody, 3E10, and active fragments thereof that selectively are transported in vivo to the nucleus of mammalian cells without cytotoxic effect are provided. The antibody and other molecules that bind to a variant of myosin IIb heavy chain found in the nucleus of skeletal muscle cells are useful as a non-viral delivery vector to target skeletal muscle in vivo. By contrast, in vitro the monoclonal antibody penetrates and is transported to the nucleus of multiple cell lines derived from different tissue types and can be used in screening tests to identify molecules that modulate growth of cells, such as cancer cells. Non-cytotoxic vectors for delivering a drug, polynucleotide or polypeptide selectively to skeletal muscle cells are also provided.
FILED	Friday, March 13, 2009
APPL NO	12/404154
ART UNIT	3991 — Central Reexamination Unit (Chemical)
CURRENT CPC	Peptides C07K 16/44 (20130101) Original (OR) Class C07K 2317/77 (20130101) C07K 2317/82 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Non-Profit Organization (NPO)

09502711 — Fabrication of biscrolled fiber using carbon nanotube sheet

US 09502711	Fang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Asian Office of Aerospace Research and Development (AOARD) Department of the Navy (DON) Office of Naval Research (ONR) Multidisciplinary University Research Initiative (MURI) Non-Profit Organization (NPO) Robert A. Welch Foundation National Science Foundation (NSF)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Shaoli Fang (Richardson, Texas); Marcio Dias Lima (Richardson, Texas); Xavier N. Lepro-Chavez (Richardson, Texas); Javier Carretero-Gonzalez (Dallas, Texas); Elizabeth Castillo-Martinez (Dallas, Texas); Raquel Ovalle-Robles (Sachse, Texas); Carter Sebastian Haines (Murphy, Texas); David Michael Novitski (Richardson, Texas); Mohammad H. Haque (Dallas, Texas); Chihye Lewis-Azad (Dallas, Texas); Mikhail Kozlov (Dallas, Texas); Anvar A. Zakhidov (McKinney, Texas); Ray H. Baughman (Dallas, Texas)
ABSTRACT	Fabrication of yarns or other shaped articles from materials in powder form (or nanoparticles or nanofibers) using carbon nanotube/nanofiber sheet as a platform (template). This includes methods for fabricating biscrolled yarns using carbon nanotube/nanofiber sheets and biscrolled fibers fabricated thereby.
FILED	Monday, December 14, 2015
APPL NO	14/967940
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/7007 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) A61L 17/04 (20130101) A61L 31/16 (20130101) A61L 31/024 (20130101) A61L 2300/108 (20130101) A61L 2300/414 (20130101) A61L 2300/418 (20130101) A61L 2400/12 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 21/063 (20130101) B01J 21/185 (20130101) B01J 23/42 (20130101) B01J 35/004 (20130101) B01J 35/0006 (20130101) B01J 35/06 (20130101) B01J 37/0215 (20130101) B01J 37/0238 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 3/12 (20130101) B05D 5/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/04 (20130101) C23C 14/58 (20130101) C23C 16/04 (20130101) C23C 16/56 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/16 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) Original (OR) Class H01M 4/96 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/0402 (20130101) H01M 4/587 (20130101) H01M 4/1391 (20130101) H01M 4/1393 (20130101) H01M 4/5825 (20130101) H01M 8/00 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Y02E 60/122 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2918 (20150115) Y10T 428/2929 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

09501748 — Mixed coupling between a qubit and resonator

US 09501748	Naaman et al.
FUNDED BY
APPLICANT(S)	Ofer Naaman (Ellicott City, Maryland); Zachary Kyle Keane (Baltimore, Maryland); David George Ferguson (Takoma Park, Maryland); Joel D. Strand (Ellicott City, Maryland)
ASSIGNEE(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S)	Ofer Naaman (Ellicott City, Maryland); Zachary Kyle Keane (Baltimore, Maryland); David George Ferguson (Takoma Park, Maryland); Joel D. Strand (Ellicott City, Maryland)
ABSTRACT	Quantum systems are provided, including a qubit and a transmission line resonator having an associated resonant wavelength. A coupling capacitor is configured to capacitively couple the qubit to the transmission line resonator. A transformer is configured to inductively couple the qubit to the transmission line resonator. A selected one of an associated capacitance of the coupling capacitor and an associated mutual inductance of the transformer is a function of a location of the qubit along the transmission line resonator.
FILED	Tuesday, November 04, 2014
APPL NO	14/532638
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/00 (20130101) H01P 7/08 (20130101) H01P 7/082 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09501874 — Extendable condition-based maintenance

US 09501874	Das et al.
FUNDED BY
APPLICANT(S)	Lockheed Martin Corporation (Bethesda, Maryland)
ASSIGNEE(S)	Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S)	Sreerupa Das (Oviedo, Florida); Joshua P. Foster (Orlando, Florida); Ryan A. Mortimer (Orlando, Florida)
ABSTRACT	A flexible condition-based maintenance (CBM) device is disclosed. A CBM device receives a plurality of sensor signals generated by corresponding sensors. The sensor signals indicate real-time conditions of components. The sensor signals are processed to generate sensor data that quantifies the real-time conditions of the components. The CBM device loads a CBM module that implements a plurality of externally invokable functions. The CBM device receives an analytics script. The first analytics script comprises a plurality of interpretable commands, and some of the plurality of interpretable commands are configured to invoke some of the plurality of externally invokable functions. The CBM module invokes a command interpreter module to interpret at least one interpretable command and generate command executable bytecodes. The command executable bytecodes are executed to generate a notification identifying a real-time condition of a component for presentation on a display device.
FILED	Friday, April 17, 2015
APPL NO	14/689264
ART UNIT	3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0213 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/006 (20130101) Original (OR) Class G07C 5/0808 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 22, 2016.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2016/fedinvent-patents-20161122.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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