FedInvent™ Patents

Patent Details for Tuesday, December 20, 2016 

This page was updated on Monday, March 27, 2023 at 04:55 AM GMT

Department of Health and Human Services (HHS) 

US 09521955 Ma et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Hongtao Ma (Bethesda, Maryland);  Theodore H. Schwartz (Scarsdale, New York);  Jian-young Wu (Gaithersburg, Maryland)
ASSIGNEE(S) CORNELL RESEARCH FOUNDTION, INC. (Ithaca, New York);  GEORGETOWN UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) Hongtao Ma (Bethesda, Maryland);  Theodore H. Schwartz (Scarsdale, New York);  Jian-young Wu (Gaithersburg, Maryland)
ABSTRACT A subdural electro-optical sensor system may include a substrate to which is attached an array of electrodes, light emitters, and light detectors. The sensor system may be sufficiently thin, flexible, sterile and biocompatible to be positioned subdurally.
FILED Monday, May 05, 2008
APPL NO 12/598543
ART UNIT 3737 — SELECT * FROM codes_techcenter;
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0084 (20130101)
A61B 5/0086 (20130101) Original (OR) Class
A61B 5/4076 (20130101)
A61B 2562/046 (20130101)
A61B 2562/0233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09521982 Hsieh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Defense Science and Engineering Graduate Fellowship (NDSEG)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Scott Hsieh (Anaheim, California);  Norbert J. Pelc (Los Altos, California)
ABSTRACT A CT apparatus for scanning an object is provided. An x-ray source is provided, wherein the x-ray source provides a collimated x-ray beam with a cross-section. A plurality of attenuation elements is provided between the source and object. An actuator is connected to the attenuation elements for moving the attenuation elements. An x-ray detector is located on an opposite side of the object from the x-ray source and is for detecting x-rays that pass through the object and the plurality of attenuation elements. A gantry rotates the x-ray source, the plurality of attenuation elements, and the x-ray detector around an axis of rotation.
FILED Wednesday, July 16, 2014
APPL NO 14/333459
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/06 (20130101)
A61B 6/035 (20130101)
A61B 6/44 (20130101)
A61B 6/405 (20130101) Original (OR) Class
A61B 6/4035 (20130101)
A61B 6/4042 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/20 (20130101)
G02B 5/22 (20130101)
G02B 5/201 (20130101)
G02B 26/02 (20130101)
G02B 26/023 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522081 D'Ambrosio et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Raimondo D'Ambrosio (Seattle, Washington);  Jason Fender (Bonney Lake, Washington);  Jeffrey Ojemann (Seattle, Washington);  John W. Miller (Bellevue, Washington);  Matthew Smyth (Frontenac, Missouri);  Steven M. Rothman (Clayton, Missouri)
ASSIGNEE(S) University of Washington (Seattle, Washington);  Washington University (St. Louis, Missouri);  Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Raimondo D'Ambrosio (Seattle, Washington);  Jason Fender (Bonney Lake, Washington);  Jeffrey Ojemann (Seattle, Washington);  John W. Miller (Bellevue, Washington);  Matthew Smyth (Frontenac, Missouri);  Steven M. Rothman (Clayton, Missouri)
ABSTRACT Passive prosthetic devices for focally cooling a brain and methods for inhibiting seizures are disclosed. The prosthetic devices replace a thermally insulating bone flap with a thermally conductive insert having an inner surface that contacts the relatively warm meninges or brain and an outer surface that contacts the relatively cool scalp. In an embodiment, the prosthesis is unitary; in another, a biocompatible casing is filled with a highly conductive core; in another, a filled polymer block is attached to a plate; and in another, the bone flap is filled with a conductive polymer. In one embodiment, a filled polymer containing elements that exhibit the magnetocaloric effect provide heat transfer that can be enhanced by application of a suitable magnetic field. Focal cooling as low as 1.2° C. has been found effective at inhibiting seizures.
FILED Tuesday, May 29, 2012
APPL NO 13/482903
ART UNIT 3739 — Optics
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 7/12 (20130101) Original (OR) Class
A61F 2007/0002 (20130101)
A61F 2007/0096 (20130101)
A61F 2007/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522124 Puglielli
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Luigi Puglielli (Madison, Wisconsin)
ABSTRACT Pharmaceutical compositions for treating Alzheimer's disease are disclosed. The pharmaceutical compositions include a compound having the general formula:
and a pharmaceutically acceptable carrier. Methods for treating Alzheimer's disease, inhibiting ATase I and/or ATase 2, reducing the activity of BACE1, reducing the level of amyloid β-peptide (Aβ), and/or reducing the level of APP intracellular domain peptide (AICD) by administering such compositions are also disclosed.
FILED Friday, February 20, 2015
APPL NO 14/627398
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/136 (20130101) Original (OR) Class
A61K 31/137 (20130101)
A61K 31/496 (20130101)
A61K 31/498 (20130101)
A61K 31/538 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522131 Reed et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Jess Dreher Reed (Madison, Wisconsin);  Dhanansayan Shanmuganayagam (Madison, Wisconsin);  Christian Gerald Krueger (Cambridge, Wisconsin);  Kenneth Allan Kudsk (Madison, Wisconsin);  Joseph Francis Pierre (Chicago, Illinois);  Aaron F. Heneghan (Middleton, Wisconsin);  Rodrigo P. Feliciano (Madison, Wisconsin)
ABSTRACT Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
FILED Friday, January 10, 2014
APPL NO 14/152267
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 1/296 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0029 (20130101)
A61K 31/353 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522136 Raines et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts);  ANNOVATION BIOPHARMA, LLC. (Cambridge, Massachusetts)
ASSIGNEE(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts);  ANNOVATION BIOPHARMA, INC. (Cambridge, Massachusetts)
INVENTOR(S) Douglas E. Raines (Wayland, Massachusetts);  Syed Shaukat Husain (Newton, Massachusetts);  John C. R. Randle (Brookline, Massachusetts)
ABSTRACT Provided herein are compounds according to formula (I): provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.
FILED Friday, July 24, 2015
APPL NO 14/808413
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)
A61K 31/454 (20130101)
A61K 31/4174 (20130101) Original (OR) Class
A61K 31/4178 (20130101)

Heterocyclic Compounds
C07D 233/54 (20130101)
C07D 233/90 (20130101)
C07D 401/06 (20130101)
C07D 401/12 (20130101)
C07D 405/06 (20130101)
C07D 405/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522156 Freeman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
U.S. State Government
State of Oregon
APPLICANT(S) The UAB Research Foundation (Birmingham, Alabama);  State of Oregon Acting By and Through the Board of Education on Behalf of the University of Oregon (Eugene, Oregon);  University College Cardiff Consultants Limited (Cardiff, United Kingdom);  Morehouse School of Medicine, Inc. (Atlanta, Georgia)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama);  The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon (Eugen, Oregon);  University College Cardiff Consultants Limited (Cardiff, United Kingdom);  Morehouse School of Medicine, Inc. (Atlanta, Georgia)
INVENTOR(S) Bruce A. Freeman (Pittsburgh, Pennsylvania);  Francisco Schopfer (Pittsburgh, Pennsylvania);  Valerie O'Donnell (Penarth, United Kingdom);  Paul Baker (Pittsburgh, Pennsylvania);  Yuqing E. Chen (Ann Arbor, Michigan);  Bruce Branchaud (Eugene, Oregon)
ABSTRACT Described herein are nitrated lipids and methods of making and using the nitrated lipids.
FILED Wednesday, February 10, 2016
APPL NO 15/040376
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/21 (20130101)
A61K 31/201 (20130101)
A61K 31/202 (20130101)
A61K 31/575 (20130101) Original (OR) Class
A61K 45/06 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 43/02 (20130101)

Acyclic or Carbocyclic Compounds
C07C 205/03 (20130101)
C07C 205/50 (20130101)
C07C 205/51 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522159 Schramm et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Albert Einstein College of Medicine, Inc. (Bronx, New York);  Victoria Link Limited (Wellington, New Zealand)
ASSIGNEE(S) Albert Einstein College of Medicine, Inc. (Bronx, New York);  Victoria Link Limited (Wellington, New Zealand)
INVENTOR(S) Vern L. Schramm (New Rochelle, New York);  Peter Charles Tyler (Wellington, New Zealand);  Richard Fröhlich (Graz, Austria)
ABSTRACT Methods and devices are disclosed for treating or preventing infections in a subject due to Pseudomonas aeruginosa using coformycin analogs and inhibitors of Pseudomonas aeruginosa 5′-methylthioadenosine deaminase (MTADA).
FILED Tuesday, September 10, 2013
APPL NO 14/426775
ART UNIT 1673 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7056 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 29/16 (20130101)
A61L 31/16 (20130101)
A61L 2300/406 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/978 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522162 Prestwich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Glenn D. Prestwich (Eastsound, Washington);  Siam Oottamasathien, VIII (Salt Lake City, Utah);  Wanjian Jia (Salt Lake City, Utah);  Lindsi McCoard (Salt Lake City, Utah);  Won Yong Lee (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Glenn D. Prestwich (Eastsound, Washington);  Siam Oottamasathien, VIII (Salt Lake City, Utah);  Wanjian Jia (Salt Lake City, Utah);  Lindsi McCoard (Salt Lake City, Utah);  Won Yong Lee (Salt Lake City, Utah)
ABSTRACT Described herein are methods for treating or preventing urological inflammation in a subject comprising administering to the subject an effective amount of a compound comprising a. a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and at least one primary C-6 hydroxyl position of an N-acetyl-glucosamine residue comprising an alkyl group or fluoroalkyl group; b. a partially or fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof, or a combination thereof.
FILED Friday, March 23, 2012
APPL NO 14/006771
ART UNIT 1673 — Organic Chemistry
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 2/38 (20130101)
A23L 2/52 (20130101)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0034 (20130101)
A61K 31/728 (20130101) Original (OR) Class
A61K 31/737 (20130101)
A61K 31/737 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Polysaccharides; Derivatives Thereof
C08B 37/0072 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522163 Otterbein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Yale University (New Haven, Connecticut)
INVENTOR(S) Leo E. Otterbein (Beverly, Massachusetts);  Augustine M. K. Choi (Pittsburgh, Pennsylvania);  Brian Scott Zuckerbraun (Pittsburgh, Pennsylvania)
ABSTRACT The present invention relates to a method of treating hepatitis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
FILED Monday, December 02, 2013
APPL NO 14/094140
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 33/00 (20130101) Original (OR) Class
A61K 33/00 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522164 Ayene et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Lankenau Institute for Medical Research (Wynnewood, Pennsylvania)
ASSIGNEE(S) LANKENAU INSTITUTE FOR MEDICAL RESEARCH (Wynnewood, Pennsylvania)
INVENTOR(S) Iraimoudi S. Ayene (Newtown Square, Pennsylvania);  George C. Prendergast (Penn Valley, Pennsylvania)
ABSTRACT Compositions and methods for the treatment of cancer are provided.
FILED Tuesday, November 19, 2013
APPL NO 14/084064
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/10 (20130101)
A61K 31/10 (20130101)
A61K 31/194 (20130101)
A61K 31/194 (20130101)
A61K 31/198 (20130101)
A61K 31/198 (20130101)
A61K 31/7048 (20130101)
A61K 33/24 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522179 Dinarello et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Non-Profit Organization (NPO)
American Heart Association (AHA)
Juvenile Diabetes Research Foundation (JDRF)
APPLICANT(S) Charles A. Dinarello (Boulder, Colorado);  Antonio Abbate (Glen Allen, Virginia);  Eli C. Lewis (Be'er Sheva, Israel)
ASSIGNEE(S) VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia);  THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
INVENTOR(S) Charles A. Dinarello (Boulder, Colorado);  Antonio Abbate (Glen Allen, Virginia);  Eli C. Lewis (Be'er Sheva, Israel)
ABSTRACT Embodiments herein report methods and compositions for treating cardiac conditions. In certain embodiments, compositions and methods relate to reducing, inhibiting or treating a subject having or suspected of undergoing cardiac remodeling after a cardiac event. Other embodiments herein relate to compounds including naturally occurring and synthetic compositions of alpha-1 antitrypsin and fragments thereof.
FILED Friday, March 04, 2011
APPL NO 13/582724
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/57 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522180 Shea et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Lonnie D. Shea (Evanston, Illinois);  Stephen D. Miller (Evanston, Illinois);  Jonathan Woon Teck Yap (Evanston, Illinois);  Daniel R. Getts (Washington, District of Columbia);  Derrick McCarthy (Evanton, Illinois)
ABSTRACT The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles In particular, PLG particles are surface-functionalized to allow for coupling of peptide molecules to the surface of the particles (e.g., for use in eliciting induction of immunological tolerance).
FILED Friday, April 03, 2015
APPL NO 14/678863
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 9/1647 (20130101)
A61K 9/5153 (20130101)
A61K 39/00 (20130101)
A61K 39/0008 (20130101) Original (OR) Class
A61K 47/48815 (20130101)
A61K 47/48907 (20130101)
A61K 47/48915 (20130101)
A61K 2039/577 (20130101)
A61K 2039/622 (20130101)
A61K 2039/55555 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522183 Paulson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) James C. Paulson (Del Mar, California);  Matthew Macauley (San Diego, California);  David Nemazee (San Diego, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) James C. Paulson (Del Mar, California);  Matthew Macauley (San Diego, California);  David Nemazee (San Diego, California)
ABSTRACT The present invention provides liposomal compositions for inducing immune tolerance. The compounds typically comprise a liposome displaying a specific antigen and also a binding moiety for a sialic acid binding Ig-like lectin (Siglec)expressed on B cells. The invention also provides methods for inducing tolerance to a protein or polypeptide antigen (e.g., a protein antigen) in a subject. The methods involve administering to the subject a pharmaceutical composition that co-presents both the antigen and a glycan ligand for a Siglec expressed on B lymphocytes.
FILED Friday, July 29, 2011
APPL NO 13/261580
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 39/001 (20130101)
A61K 39/35 (20130101)
A61K 39/385 (20130101) Original (OR) Class
A61K 47/48815 (20130101)
A61K 2039/55555 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522187 Ross
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky);  Trunetta Jo Dockter Ross (, None)
ASSIGNEE(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S) Gordon D. Ross (Prospect, Kentucky)
ABSTRACT The present invention relates to methods of using neutral soluble glucan and monoclonal antibodies for antitumor therapy. Neutral soluble Beta (1,3; 1,6) glucan (NSG) enhances the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. The glucan does not stimulate the induction of inflammatory cytokines. Also described are methods of using whole glucan particles (WGP) as an immunomodulator by inducing a shift from a Th2 response to the Th1 response, leading to an enhanced antitumor cytotoxic T-cell response.
FILED Thursday, October 30, 2014
APPL NO 14/528900
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/715 (20130101)
A61K 31/716 (20130101)
A61K 39/39558 (20130101) Original (OR) Class
A61K 39/39558 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522193 Walz
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) OPHIDION INC. (Pasadena, California)
ASSIGNEE(S) OPHIDION INC. (Bethlehem, Pennsylvania)
INVENTOR(S) Andreas Walz (Pasadena, California)
ABSTRACT Compositions and methods are provided including a transporter peptide derived from the loop2 domain of the neuronally-derived lynx1 protein which can be conjugated to an effector agent to form a transporter-effector complex for transport of the therapeutic effector agent to a target that is found across the blood brain barrier.
FILED Monday, December 09, 2013
APPL NO 14/101196
ART UNIT 1675 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 31/713 (20130101)
A61K 31/7088 (20130101)
A61K 31/7088 (20130101)
A61K 45/06 (20130101)
A61K 47/48169 (20130101)
A61K 47/48246 (20130101) Original (OR) Class
A61K 48/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 14/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522198 Ruoslahti et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sanford-Burnham Medical Research Institute (La Jolla, California)
ASSIGNEE(S) Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S) Erkki Ruoslahti (Buelton, California);  Jan Pilch (Pittsburgh, Pennsylvania)
ABSTRACT Disclosed are compositions and methods useful for targeting tumors, sites of injury and blood clots. The compositions and methods are based on peptide sequences that selectively bind to and home to tumors, sties of injury and blood clots in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tumors, sites of injury and blood clots.
FILED Monday, July 14, 2014
APPL NO 14/331048
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101)
A61K 38/10 (20130101)
A61K 38/12 (20130101)
A61K 38/16 (20130101)
A61K 38/17 (20130101)
A61K 47/48246 (20130101)
A61K 49/14 (20130101)
A61K 49/0043 (20130101)
A61K 49/0056 (20130101) Original (OR) Class
A61K 49/085 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 7/64 (20130101)
C07K 14/00 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)
C07K 2319/035 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522871 Wainer et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Irving William Wainer (Washington, District of Columbia);  Weizhong Zhu (Philadelphia, Pennsylvania);  Khalid Chakir (Baltimore, Maryland);  Rui-Ping Xiao (Baltimore, Maryland);  Darrell R. Abernethy (Annapolis, Maryland);  Farideh M. Beigi Abhari (Durham, North Carolina)
ABSTRACT This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.
FILED Thursday, March 06, 2014
APPL NO 14/199208
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 215/60 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522881 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) Zhong-Yin Zhang (Carmel, Indiana);  Li-Fan Zeng (Indianapolis, Indiana)
ABSTRACT Inhibitors of protein tyrosine phosphatases are disclosed. The inhibitors include hydroxyindole carboxylic acids having a linker and an amine scaffold that are potent inhibitors of Src homology 2-domain containing protein tyrosine phosphatase-2.
FILED Friday, April 25, 2014
APPL NO 14/786621
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/404 (20130101)
A61K 31/405 (20130101)
A61K 31/426 (20130101)
A61K 31/433 (20130101)
A61K 31/4178 (20130101)
A61K 31/4184 (20130101)

Heterocyclic Compounds
C07D 209/24 (20130101) Original (OR) Class
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 409/12 (20130101)
C07D 417/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522943 Lally et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Rhode Island Hospital, A Lifespan-Partner (Providence, Rhode Island)
ASSIGNEE(S) Rhode Island Hospital, A Lifespan-Partner (Providence, Rhode Island)
INVENTOR(S) Michelle Lally (Cumberland, Rhode Island);  Bharat Ramratnam (Tiverton, Rhode Island);  Ming Li (Cranston, Rhode Island)
ABSTRACT Methods and compositions for determining a prognosis for a subject infected with HIV, reducing a risk of an HIV infection, and treating or reducing a risk of developing AIDS are described.
FILED Friday, January 18, 2013
APPL NO 14/378715
ART UNIT 1675 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/47 (20130101) Original (OR) Class
C07K 2319/85 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56988 (20130101)
G01N 2333/4703 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522944 Rapraeger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Alan C. Rapraeger (Stoughton, Wisconsin);  DeannaLee M. Beauvais (Monona, Wisconsin)
ABSTRACT The present invention provides a peptide derived from the extracellular domain of syndecan-1 that inhibits angiogenesis.
FILED Friday, January 04, 2013
APPL NO 13/734302
ART UNIT 1676 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 7/08 (20130101)
C07K 14/705 (20130101)
C07K 14/4725 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522948 Restifo et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Nicholas P. Restifo (Chevy Chase, Maryland);  Lydie Cassard (Antony, France);  Zhiya Yu (Potomac, Maryland);  Steven A. Rosenberg (Potomac, Maryland)
ABSTRACT The invention provides human cells, particularly human T cells, comprising a murine T Cell Receptor (TCR) having antigen specificity for the cancer antigen gp100. Isolated or purified TCRs having antigenic specificity for amino acids 154-162 of gp100 (SEQ ID NO: 1), as well as related polypeptides, proteins, nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding fragments thereof, conjugates, and pharmaceutical compositions, are further provided. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host comprising the use of the inventive materials described herein.
FILED Friday, December 13, 2013
APPL NO 14/106031
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/7051 (20130101)
C07K 14/70503 (20130101) Original (OR) Class
C07K 16/30 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
C12N 15/86 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522955 Rosenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Steven A. Rosenberg (Potomac, Maryland);  Dhanalakshmi Chinnasamy (North Potomac, Maryland)
ABSTRACT The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of a KDR-1121 or DC101 antibody, an extracellular hinge domain, a T cell receptor transmembrane domain, and an intracellular domain T cell receptor signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a host and methods of treating or preventing cancer in a host are also disclosed.
FILED Friday, August 08, 2014
APPL NO 14/454820
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/7051 (20130101)
C07K 14/70521 (20130101)
C07K 16/42 (20130101)
C07K 16/2863 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523075 Takayama et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Shuichi Takayama (Ann Arbor, Michigan);  Gary D. Smith (Ann Arbor, Michigan);  Timothy G. Schuster (Ann Arbor, Michigan);  Brenda S. Cho (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Shuichi Takayama (Ann Arbor, Michigan);  Gary D. Smith (Ann Arbor, Michigan);  Timothy G. Schuster (Ann Arbor, Michigan);  Brenda S. Cho (Ann Arbor, Michigan)
ABSTRACT Motile particles are sorted from non-motile particles in a microfluidic sorting device wherein a stream of sort fluid containing motile and non-motile particles is caused to flow adjacent a media stream in non-turbulent fashion through a sort channel, during which flow motile particles cross the interface between the adjacent flow streams, entering the media stream, and forming a motile particle-depleted sort stream. The sorting devices are easily and inexpensively fabricated and have numerous uses, in particular sorting of motile from non-motile sperm.
FILED Wednesday, April 02, 2008
APPL NO 12/061482
ART UNIT 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0612 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523078 Sackstein
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Robert Sackstein (Sudbury, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Robert Sackstein (Sudbury, Massachusetts)
ABSTRACT The invention features methods and compositions for treating hematopoietic disorders, inflammatory conditions, and cancer and providing stem cell therapy in a mammal.
FILED Thursday, June 21, 2012
APPL NO 13/529530
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2035/124 (20130101)

Peptides
C07K 14/70585 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0647 (20130101) Original (OR) Class
C12N 2501/59 (20130101)
C12N 2501/90 (20130101)
C12N 2501/599 (20130101)
C12N 2501/724 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523079 Nam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Young-Jae Nam (Nashville, Tennessee);  Kunhua Song (Aurora, Colorado);  Eric N. Olson (Dallas, Texas)
ABSTRACT The present invention involves the use of transcription factors including Tbx5, Mef2C, Hand2, myocardin and Gata4 to reprogram cardiac fibroblasts into cardiomyocytes, both in vitro and in vivo. Such methods find particular use in the treatment of patients post-myocardial infarction to prevent or limit scarring and to promote myocardial repair.
FILED Tuesday, April 28, 2015
APPL NO 14/697955
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)
A61K 38/00 (20130101)
A61K 38/17 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0657 (20130101) Original (OR) Class
C12N 2501/40 (20130101)
C12N 2770/00043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523093 Davidson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Beverly L. Davidson (Iowa City, Iowa);  Alejandro Mas Monteys (Iowa City, Iowa)
ABSTRACT The present invention is directed to RNA interference (RNAi) molecules targeted against a Huntington's disease nucleic acid sequence, and methods of using these RNAi molecules to treat Huntington's disease.
FILED Wednesday, May 20, 2015
APPL NO 14/717795
ART UNIT 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0085 (20130101)
A61K 31/7088 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/141 (20130101)
C12N 2320/30 (20130101)
C12N 2320/32 (20130101)
C12N 2330/51 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523101 Rao
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Catholic University of America (Washington, District of Columbia)
ASSIGNEE(S) The Catholic University of America (Washington, District of Columbia)
INVENTOR(S) Venigalla B. Rao (Silver Spring, Maryland)
ABSTRACT Complex viruses are assembled from simple protein subunits by sequential and irreversible assembly. During genome packaging in bacteriophages, a powerful molecular motor assembles at the special portal vertex of an empty prohead to initiate packaging. An aspect of the invention relates to the phage T4 packaging machine being highly promiscuous, translocating DNA into finished phage heads as well as into proheads. Single motors can force exogenous DNA into phage heads at the same rate as into proheads and phage heads undergo repeated initiations, packaging multiple DNA molecules into the same head. This shows that the phage DNA packaging machine has unusual conformational plasticity, powering DNA into an apparently passive capsid receptacle, including the highly stable virus shell, until it is full. These features allow for the design of a novel class of nanocapsid delivery vehicles.
FILED Wednesday, July 02, 2014
APPL NO 14/322097
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/711 (20130101)
A61K 31/7088 (20130101)
A61K 47/48776 (20130101)
A61K 48/00 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 15/87 (20130101)
C12N 15/88 (20130101)
C12N 2795/10042 (20130101)
C12N 2795/10122 (20130101)
C12N 2795/10142 (20130101)
C12N 2795/10152 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523120 Vats
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Abhay N. Vats (Wexford, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Abhay N. Vats (Wexford, Pennsylvania)
ABSTRACT A nucleic acid amplification method is provided, along with kits useful in performing the amplification method.
FILED Thursday, June 14, 2012
APPL NO 14/125450
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101) Original (OR) Class
C12Q 1/689 (20130101)
C12Q 1/701 (20130101)
C12Q 1/6853 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523126 Drake et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Charles G. Drake (Baltimore, Maryland);  Drew M. Pardoll (Brookeville, Maryland);  Jonathan D. Powell (Baltimore, Maryland);  Derese Getnet (Baltimore, Maryland);  Edward L. Hipkiss (Baltimore, Maryland);  Joseph F. Grosso (Towson, Maryland)
ABSTRACT The invention generally features compositions and methods for modulating an immune response. In particular embodiments, such compositions and methods modulate regulatory T cell suppressive activity.
FILED Tuesday, May 20, 2014
APPL NO 14/282338
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6881 (20130101) Original (OR) Class
C12Q 2600/136 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523127 Singh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Nanda A. Singh (Heber City, Utah);  Mark F. Leppert (Salt Lake City, Utah);  Carole Charlier (Sprimont, Belgium)
ASSIGNEE(S) THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Nanda A. Singh (Heber City, Utah);  Mark F. Leppert (Salt Lake City, Utah);  Carole Charlier (Sprimont, Belgium)
ABSTRACT Generalized idiopathic epilepsies (IGE) cause 40% of all seizures and commonly have a genetic basis. One type of IGE is Benign Familial Neonatal Convulsions (BFNC), a dominantly inherited disorder of newborns. A submicroscopic deletion of chromosome 20q13.3 which co-segregates with seizures in a BFNC family has been identified. Characterization of cDNAs spanning the deleted region identified a novel voltage-gated potassium channel, KCNQ2, which belongs to a new KCNQ1-like class of potassium channels. Nine other BFNC probands were shown to have KCNQ2 mutations including three missense mutations, three frameshifts, two nonsense mutations, and one splice site mutation. A second gene, KCNQ3, was found in a separate BFNC family in which the mutation had been localized to chromosome 8. A missense mutation was found in this gene in perfect cosegregation with the BFNC phenotype in this latter family. This demonstrates that defects in potassium channels can cause epilepsy. Furthermore, some members of one of the BFNC families with a mutation in KCNQ2 also exhibited rolandic epilepsy and one individual with juvenile myoclonic epilepsy has a mutation in an alternative exon of KCNQ3.
FILED Monday, February 05, 2007
APPL NO 11/702218
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 2217/05 (20130101)

Peptides
C07K 14/705 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523128 Cairns et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S) Nigel J. Cairns (St. Louis, Missouri);  Robert H. Baloh (St. Louis, Missouri);  Alan Pestronk (St. Louis, Missouri);  Michael A. Gitcho (St. Louis, Missouri);  Alison M. Goate (St. Louis, Missouri)
ABSTRACT The present invention provides nucleic acids and peptides, and methods of using the nucleic acids and peptides to identify subjects at risk for a TDP-43 proteinopathy. The invention also provides for an array comprising the nucleic acids and peptides of the invention.
FILED Tuesday, October 14, 2014
APPL NO 14/514104
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/47 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523680 Lim et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Mark J. Lim (Reading, Massachusetts);  Kenneth J. Rothschild (Newton, Massachusetts)
ASSIGNEE(S) AmberGen, Inc. (Watertown, Massachusetts)
INVENTOR(S) Mark J. Lim (Reading, Massachusetts);  Vladislav B. Bergo (Boston, Massachusetts);  Kenneth J. Rothschild (Newton, Massachusetts)
ABSTRACT Methods for proteomic screening on random protein-bead arrays by mass spec is described. Photocleavable mass tags are utilized to code a protein library (bait molecules) displayed on beads randomly arrayed in an array substrate. A library of probes (prey) can be mixed with the protein-bead array to query the array. Because mass spec can detect multiple mass tags, it is possible to rapidly identify all of the interactions resulting from this mixing.
FILED Wednesday, June 29, 2011
APPL NO 13/172164
ART UNIT 1678 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6845 (20130101)
G01N 33/6848 (20130101)
G01N 33/54306 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523684 Herr et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Amy E. Herr (Oakland, California);  Alex James Hughes (Berkeley, California)
ABSTRACT Microfluidic devices and methods for using the same are provided. Aspects of the present disclosure include microfluidic devices that include a separation medium having functional groups which covalently bond to one or more analytes of interest, e.g., proteins, in a sample upon application of an applied stimulus, e.g., light. Also provided are methods of using the devices as well as systems and kits that include the devices. The devices, systems and methods find use in a variety of different applications, including diagnostic and validation assays.
FILED Monday, July 13, 2015
APPL NO 14/798103
ART UNIT 1677 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5023 (20130101)
B01L 3/5027 (20130101)
B01L 3/502753 (20130101)
B01L 2200/10 (20130101)
B01L 2300/069 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/1861 (20130101)
B01L 2400/0418 (20130101)
B01L 2400/0496 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44756 (20130101)
G01N 33/559 (20130101) Original (OR) Class
G01N 33/561 (20130101)
G01N 33/54366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523686 Raychaudhuri et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Inbios International, Inc. (Seattle, Washington)
ASSIGNEE(S) InBios International, Inc. (Seattle, Washington)
INVENTOR(S) Syamal Raychaudhuri (Seattle, Washington);  Raymond L. Houghton (Bothell, Washington);  Stanislaw Morkowski (Seattle, Washington);  Yvonne Stevens (Bellevue, Washington);  Mohua Bose (Redmond, Washington);  James William Needham (Seattle, Washington);  Hongjing Chen (Seattle, Washington)
ABSTRACT The present invention provides monoclonal antibodies that are specific for the Dengue non-structural glycoprotein NS1 in monomeric and/or oligomeric (primarily dimeric) form, together with methods, including ELISA and lateral flow assays, that employ the disclosed antibodies for the early detection of Dengue virus infection. Diagnostic kits for the detection of Dengue infection are also provided, such kits including the disclosed monoclonal and/or polyclonal antibodies.
FILED Wednesday, December 10, 2014
APPL NO 14/566321
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/1081 (20130101)
C07K 2317/33 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/558 (20130101)
G01N 33/54366 (20130101)
G01N 33/56983 (20130101) Original (OR) Class
G01N 2333/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523695 Kipps et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Thomas J. Kipps (Rancho Santa Fe, California);  George F. Widhopf, II (San Diego, California);  Bing Cui (San Diego, California)
ABSTRACT Therapeutic antibodies having binding specificity for ROR-1 expressed on cancer cells (particularly leukemic and lymphomic cells) and pharmaceutical compositions containing one or more such antibodies for use in treating cancer. Methods for diagnosing such cancers through in vitro detection of binding to ROR-1 protein expressed on putative cancer cells are also provided.
FILED Friday, September 04, 2015
APPL NO 14/846400
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/40 (20130101)
C07K 16/2803 (20130101)
C07K 2317/73 (20130101)
C07K 2317/77 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6854 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524232 Bhattacharjee et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Abhishek Bhattacharjee (Princeton, New Jersey);  Margaret Martonosi (Skillman, New Jersey)
ABSTRACT A chip multiprocessor includes a plurality of cores each having a translation lookaside buffer (TLB) and a prefetch buffer (PB). Each core is configured to determine a TLB miss on the core's TLB for a virtual page address and determine whether or not there is a PB hit on a PB entry in the PB for the virtual page address. If it is determined that there is a PB hit, the PB entry is added to the TLB. If it is determined that there is not a PB hit, the virtual page address is used to perform a page walk to determine a translation entry, the translation entry is added to the TLB and the translation entry is prefetched to each other one of the plurality of cores.
FILED Friday, October 03, 2014
APPL NO 14/506203
ART UNIT 2135 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0215 (20130101) Original (OR) Class
G06F 12/0862 (20130101)
G06F 12/1009 (20130101)
G06F 12/1027 (20130101)
G06F 2212/654 (20130101)
G06F 2212/681 (20130101)
G06F 2212/682 (20130101)
G06F 2212/684 (20130101)
G06F 2212/1016 (20130101)
G06F 2212/6022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524373 Segal
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) SimulConsult, Inc. (Chestnut Hill, Massachusetts)
ASSIGNEE(S) SimulConsult, Inc. (Chestnut Hill, Massachusetts)
INVENTOR(S) Michael M. Segal (Chestnut Hill, Massachusetts)
ABSTRACT The present invention features methods, devices, and systems, e.g., for providing diagnostic or treatment decision support to a clinician for the diagnosis or treatment of a patient in need thereof or for diagnosing or treating a patient in need thereof.
FILED Thursday, February 28, 2013
APPL NO 13/781225
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electric Digital Data Processing
G06F 19/18 (20130101)
G06F 19/3437 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524552 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Hongkai Wang (Los Angeles, California);  Arion F. Hadjioannou (Los Angeles, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Hongkai Wang (Los Angeles, California);  Arion F. Hadjioannou (Los Angeles, California)
ABSTRACT A method for preparing an image simulating the anatomy of a small subject test animal, and an apparatus for producing said image and an anatomical atlas for co-registering therewith, comprising the generation of two or more non-tomographic images of the test animals is described. Examples of the non-tomographic imaging modalities and the images generated include, but are not limited to one or more x-ray sources and resultant of x-ray projections, photographic cameras and resulting digital or optical images and surface scanners and resultant surface scans. The subject animal is positioned at a focal point in a carrier in an imaging enclosure. A combination of one or more of the non-tomographic images taken from different angles within the enclosure are combined and through an iterative process co-registered with the previously generated digital atlas of the anatomy of the same or similar test animals.
FILED Wednesday, August 01, 2012
APPL NO 13/564675
ART UNIT 2881 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/03 (20130101)
A61B 6/508 (20130101)
A61B 6/583 (20130101)
A61B 6/5247 (20130101)
A61B 2503/40 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 2209/051 (20130101)

Image Data Processing or Generation, in General
G06T 7/0032 (20130101) Original (OR) Class
G06T 2207/10072 (20130101)
G06T 2207/10116 (20130101)
G06T 2207/30004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524567 Brokish et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) InstaRecon (Urbana, Illinois)
ASSIGNEE(S) InstaRecon (Urbana, Illinois)
INVENTOR(S) Jeffrey Brokish (Savoy, Illinois);  Yoram Bresler (Urbana, Illinois);  Luke Pfister (Urbana, Illinois)
ABSTRACT Methods and systems for iterative computed tomography add an auxiliary variable to the reconstruction process, while retaining all variables in the original formulation, A weighting operator or filter can be applied that causes the Hessian with respect to an image of the cost function to be well-conditioned. An auxiliary sinogram variable distinct from both a set of actual image measurements and from the set of projections computed based on an image can be applied to iteratively update during the statistical iterative image reconstruction, with applied conditions that causes the Hessian with respect to an image of the cost function to be well-conditioned.
FILED Monday, June 22, 2015
APPL NO 14/746434
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/032 (20130101)
A61B 6/5205 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/0032 (20130101)
G06T 11/006 (20130101) Original (OR) Class
G06T 2207/10081 (20130101)
G06T 2207/10116 (20130101)
G06T 2207/30004 (20130101)
G06T 2211/424 (20130101)
G06T 2215/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 09521982 Hsieh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Defense Science and Engineering Graduate Fellowship (NDSEG)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Scott Hsieh (Anaheim, California);  Norbert J. Pelc (Los Altos, California)
ABSTRACT A CT apparatus for scanning an object is provided. An x-ray source is provided, wherein the x-ray source provides a collimated x-ray beam with a cross-section. A plurality of attenuation elements is provided between the source and object. An actuator is connected to the attenuation elements for moving the attenuation elements. An x-ray detector is located on an opposite side of the object from the x-ray source and is for detecting x-rays that pass through the object and the plurality of attenuation elements. A gantry rotates the x-ray source, the plurality of attenuation elements, and the x-ray detector around an axis of rotation.
FILED Wednesday, July 16, 2014
APPL NO 14/333459
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/06 (20130101)
A61B 6/035 (20130101)
A61B 6/44 (20130101)
A61B 6/405 (20130101) Original (OR) Class
A61B 6/4035 (20130101)
A61B 6/4042 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/20 (20130101)
G02B 5/22 (20130101)
G02B 5/201 (20130101)
G02B 26/02 (20130101)
G02B 26/023 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522081 D'Ambrosio et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Raimondo D'Ambrosio (Seattle, Washington);  Jason Fender (Bonney Lake, Washington);  Jeffrey Ojemann (Seattle, Washington);  John W. Miller (Bellevue, Washington);  Matthew Smyth (Frontenac, Missouri);  Steven M. Rothman (Clayton, Missouri)
ASSIGNEE(S) University of Washington (Seattle, Washington);  Washington University (St. Louis, Missouri);  Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Raimondo D'Ambrosio (Seattle, Washington);  Jason Fender (Bonney Lake, Washington);  Jeffrey Ojemann (Seattle, Washington);  John W. Miller (Bellevue, Washington);  Matthew Smyth (Frontenac, Missouri);  Steven M. Rothman (Clayton, Missouri)
ABSTRACT Passive prosthetic devices for focally cooling a brain and methods for inhibiting seizures are disclosed. The prosthetic devices replace a thermally insulating bone flap with a thermally conductive insert having an inner surface that contacts the relatively warm meninges or brain and an outer surface that contacts the relatively cool scalp. In an embodiment, the prosthesis is unitary; in another, a biocompatible casing is filled with a highly conductive core; in another, a filled polymer block is attached to a plate; and in another, the bone flap is filled with a conductive polymer. In one embodiment, a filled polymer containing elements that exhibit the magnetocaloric effect provide heat transfer that can be enhanced by application of a suitable magnetic field. Focal cooling as low as 1.2° C. has been found effective at inhibiting seizures.
FILED Tuesday, May 29, 2012
APPL NO 13/482903
ART UNIT 3739 — Optics
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 7/12 (20130101) Original (OR) Class
A61F 2007/0002 (20130101)
A61F 2007/0096 (20130101)
A61F 2007/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522187 Ross
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky);  Trunetta Jo Dockter Ross (, None)
ASSIGNEE(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S) Gordon D. Ross (Prospect, Kentucky)
ABSTRACT The present invention relates to methods of using neutral soluble glucan and monoclonal antibodies for antitumor therapy. Neutral soluble Beta (1,3; 1,6) glucan (NSG) enhances the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. The glucan does not stimulate the induction of inflammatory cytokines. Also described are methods of using whole glucan particles (WGP) as an immunomodulator by inducing a shift from a Th2 response to the Th1 response, leading to an enhanced antitumor cytotoxic T-cell response.
FILED Thursday, October 30, 2014
APPL NO 14/528900
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/715 (20130101)
A61K 31/716 (20130101)
A61K 39/39558 (20130101) Original (OR) Class
A61K 39/39558 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522198 Ruoslahti et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sanford-Burnham Medical Research Institute (La Jolla, California)
ASSIGNEE(S) Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S) Erkki Ruoslahti (Buelton, California);  Jan Pilch (Pittsburgh, Pennsylvania)
ABSTRACT Disclosed are compositions and methods useful for targeting tumors, sites of injury and blood clots. The compositions and methods are based on peptide sequences that selectively bind to and home to tumors, sties of injury and blood clots in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tumors, sites of injury and blood clots.
FILED Monday, July 14, 2014
APPL NO 14/331048
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101)
A61K 38/10 (20130101)
A61K 38/12 (20130101)
A61K 38/16 (20130101)
A61K 38/17 (20130101)
A61K 47/48246 (20130101)
A61K 49/14 (20130101)
A61K 49/0043 (20130101)
A61K 49/0056 (20130101) Original (OR) Class
A61K 49/085 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 7/64 (20130101)
C07K 14/00 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)
C07K 2319/035 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522344 Di Carlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Dino Di Carlo (Los Angeles, California);  Daniel R. Gossett (Los Angeles, California);  Henry T. K. Tse (San Francisco, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Dino Di Carlo (Los Angeles, California);  Daniel R. Gossett (Los Angeles, California);  Henry T. K. Tse (San Francisco, California)
ABSTRACT A method of exchanging fluids with suspended particles includes providing a microfluidic device with a first inlet channel operatively coupled to a source of particles and a second inlet channel operatively coupled to an exchange fluid. A transfer channel is connected at a proximal end to the first inlet channel and the second inlet channel. First and second outlet channels are connected to a distal end of the transfer channel. The source of particles is flowed at a first flow rate into the first inlet channel while the exchange fluid is flowed at a second flow rate into the second inlet channel wherein the ratio of the second flow rate to the first flow rate is at least 1.5. Particles are collected in one of the first and second outlet channels while fluid substantially free of particles is collected in the other of the first and second outlet channels.
FILED Monday, November 14, 2011
APPL NO 13/884595
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 12/00 (20130101) Original (OR) Class

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502746 (20130101)
B01L 3/502761 (20130101)
B01L 3/502776 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/0816 (20130101)
B01L 2400/084 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2015/149 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522350 Tzipori et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Environmental Protection Agency (EPA)
APPLICANT(S) TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts);  HAEMONETICS CORPORATION (Braintree, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts);  Haemonetics Corporation (Braintree, Massachusetts)
INVENTOR(S) Saul Tzipori (Shrewsbury, Massachusetts);  Udi Zukerman (Brookline, Massachusetts);  Gary Stacey (Marshfield, Massachusetts)
ABSTRACT A method for the simultaneous concentration of multiple toxins from large volumes of water. The method includes the steps of providing a disposable separation centrifuge bowl, the centrifuge bowl including a positively charged material at it's inner core. A large water sample contaminated with toxins from a group consisting of protozoa, bacteria, bacterial spores, and toxins is delivered to the centrifuge bowl. A centrifugal force is applied to the separation bowl. The water sample is concentrated to remove large particles of the toxins in the bowl due to the centrifugal forces. The concentrated water sample is passes through the positively charged inner core to capture any remaining concentrated targets by electrostatic forces and the concentrated targets are eluted.
FILED Wednesday, November 13, 2013
APPL NO 14/079325
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Separation
B01D 21/262 (20130101) Original (OR) Class
B01D 21/302 (20130101)
B01D 2221/10 (20130101)

Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields
B03C 3/15 (20130101)
B03C 5/02 (20130101)
B03C 2201/26 (20130101)

Centrifuges
B04B 5/10 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4077 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522426 Das et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Suman Das (Atlanta, Georgia);  Rohan Bansal (Buffalo, New York);  Justin Gambone (Watervliet, New York)
ASSIGNEE(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
INVENTOR(S) Suman Das (Atlanta, Georgia);  Rohan Bansal (Buffalo, New York);  Justin Gambone (Watervliet, New York)
ABSTRACT Scanning Laser Epitaxy (SLE) is a layer-by-layer additive manufacturing process that allows for the fabrication of three-dimensional objects with specified microstructure through the controlled melting and re-solidification of a metal powders placed atop a base substrate. SLE can be used to repair single crystal (SX) turbine airfoils, for example, as well as the manufacture functionally graded turbine components. The SLE process is capable of creating equiaxed, directionally solidified, and SX structures. Real-time feedback control schemes based upon an offline model can be used both to create specified defect free microstructures and to improve the repeatability of the process. Control schemes can be used based upon temperature data feedback provided at high frame rate by a thermal imaging camera as well as a melt-pool viewing video microscope. A real-time control scheme can deliver the capability of creating engine ready net shape turbine components from raw powder material.
FILED Friday, November 08, 2013
APPL NO 14/076101
ART UNIT 2127 — AI & Simulation/Modeling
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/1055 (20130101) Original (OR) Class
B22F 5/04 (20130101)
B22F 5/009 (20130101)
B22F 2003/1057 (20130101)
B22F 2007/068 (20130101)

Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 6/007 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 67/0077 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/08 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 13/24 (20130101)
C30B 29/52 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 10/295 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522743 Tolani et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) Intelligent Automation, Inc. (Rockville, Maryland)
ASSIGNEE(S) Intelligent Automation, Inc. (Rockville, Maryland)
INVENTOR(S) Devendra Kumar Tolani (Germantown, Maryland);  Michael J. Clark (Germantown, Maryland);  Jakob P. Henriksson, I (Hyattsville, Maryland);  Jyotirmaya Nanda (Gaithersburg, Maryland);  Chujen Lin (North Potomac, Maryland)
ABSTRACT A parachute data recorder system is provided that includes a housing, the housing having a seal for resistance to moisture and environmental impact; a plurality of sensors mounted in the housing, including an accelerometer, an altimeter, a gyrometer, and a GPS; a microprocessor mounted in the housing for recording and processing data from the sensors; a wireless connection unit mounted in the housing for transmitting data in the microprocessor; and an electronic connection port. The parachute data recorder system may further include a second accelerometer, one of the accelerometers being a low-g accelerometer and the other being a high-g accelerometer. The initiation of recording can be started by stress or strain inducement from parachute deployment.
FILED Friday, November 14, 2014
APPL NO 14/541234
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/021 (20130101)
A61B 5/024 (20130101)
A61B 5/02055 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 21/00 (20130101)
B64D 23/00 (20130101)
B64D 47/00 (20130101) Original (OR) Class

Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 9/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522854 Wright et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Michael E. Wright (Ridgecrest, California);  Benjamin G. Harvey (Ridgecrest, California)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael E. Wright (Ridgecrest, California);  Benjamin G. Harvey (Ridgecrest, California)
ABSTRACT An improved process and apparatus for the selective reaction of terpenes (including mono-, sesqui-, di-terpenes, and others in the terpene family), alpha-olefin oligomers (OOA's), and related olefins to their respective dimeric product in high purity using heterogeneous acid catalyst concurrent with full utilization of energy created in the process. Embodiments of the invention carry out a unique and highly efficient dimerization of terpenes, alpha-olefin oligomers (OOA's), and olefins using cost effective catalysts and low cost equipment that are ideally suited for commercialization of jet/turbine and diesel biofuel processes producing fuels with high flashpoints and superb cold flow properties.
FILED Wednesday, March 21, 2012
APPL NO 13/426347
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 8/04 (20130101)
B01J 2219/0004 (20130101)

Acyclic or Carbocyclic Compounds
C07C 2/08 (20130101)
C07C 2/28 (20130101) Original (OR) Class
C07C 2/28 (20130101)
C07C 5/03 (20130101)
C07C 5/03 (20130101)
C07C 9/22 (20130101)
C07C 11/02 (20130101)
C07C 2531/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522908 Brown et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Georgetown University (Washington, District of Columbia)
ASSIGNEE(S) Gerogetown University (Washington, District of Columbia)
INVENTOR(S) Milton L. Brown (Brookeville, Maryland);  Mikell Paige (Fairfax, Virginia);  Jeffrey A. Torestsky (Silver Spring, Maryland);  Aykut Uren (Rockville, Maryland);  George Kosturko (Alexandria, Virginia);  Gullay Bulut (Washington, District of Columbia)
ABSTRACT The invention encompasses compound and pharmaceutical composition comprising the compound of the following Formula (I): or pharmaceutically acceptable salts or prodrugs thereof, that are useful for inhibiting ezrin protein in a cell or for inhibiting the growth of a cancer cell.
FILED Monday, October 07, 2013
APPL NO 14/047362
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 209/48 (20130101)
C07D 215/24 (20130101)
C07D 215/38 (20130101)
C07D 217/24 (20130101)
C07D 237/30 (20130101)
C07D 401/06 (20130101)
C07D 401/12 (20130101)
C07D 413/12 (20130101) Original (OR) Class
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523329 Kupratis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Daniel Bernard Kupratis (Wallingford, Connecticut);  Francis R. Moon (Granby, Connecticut)
ABSTRACT In accordance with one aspect of the disclosure, a stream diverter for a gas turbine engine is disclosed. The stream diverter may include a first air duct, a second air duct, a third air duct, and a door operatively associated with the second and third air ducts of the gas turbine engine. The door may have at least an open position allowing air from the second air duct to flow into the third air duct and a closed position preventing air from flowing between the ducts.
FILED Tuesday, July 09, 2013
APPL NO 13/937670
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/13 (20130101)
F02C 3/145 (20130101)
F02C 9/18 (20130101)

Jet-propulsion Plants
F02K 3/06 (20130101)
F02K 3/075 (20130101) Original (OR) Class
F02K 3/077 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2210/40 (20130101)
F05D 2250/311 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523547 Compton
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Logan M. Compton (Fredericksburg, Virginia)
ASSIGNEE(S) The United States Of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Logan M. Compton (Fredericksburg, Virginia)
ABSTRACT A device is provided for repairing erosion damage to a bore of a railgun with metal powder. The bore has a surface contour that extends longitudinally of the railgun. The device includes a housing, a profilometer sensor and a nozzle. The housing has a configuration that conforms to the surface contour and an upstream face on a longitudinal end. The profilometer sensor mounts to the upstream face to measure depth of the erosion and indicate a divot in the bore that involves repair to match the surface contour. The nozzle mounts to the upstream face to spray the metal powder from a reservoir within the housing in response to the divot indicated by the profilometer.
FILED Wednesday, July 08, 2015
APPL NO 14/794556
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 13/0618 (20130101)
B05B 13/0627 (20130101)

Apparatus for Applying Fluent Materials to Surfaces, in General
B05C 11/1021 (20130101)
B05C 19/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 24/04 (20130101)

Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 21/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523637 Myrick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Michael L. Myrick (Irmo, South Carolina);  David L. Perkins (Irmo, South Carolina);  Ryan J. Priore (Columbia, South Carolina)
ASSIGNEE(S) Halliburton Energy Services, Inc. (Houston, Texas)
INVENTOR(S) Michael L. Myrick (Irmo, South Carolina);  David L. Perkins (Irmo, South Carolina);  Ryan J. Priore (Columbia, South Carolina)
ABSTRACT A method of using photoacoustic spectroscopy to determine chemical information about an analyte includes the steps of emitting a light ray for interaction with a sample of an analyte; transmitting the light ray through a fill fluid disposed in a detection cell, the fill fluid having molecules substantially similar to molecules of the analyte to absorb the light ray; producing a thermal wave and oscillation in the fill fluid proportional to an intensity of the light ray; including a pressure oscillation in the fill fluid by the thermal wave; and detecting the pressure oscillation by a microphone to determine information about the analyte sample.
FILED Thursday, July 19, 2012
APPL NO 13/553381
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3504 (20130101) Original (OR) Class
G01N 2021/1704 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523770 Ruffa
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Anthony A Ruffa (Hope Valley, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Anthony A Ruffa (Hope Valley, Rhode Island)
ABSTRACT A method of use for parametric sonar is provided that utilizes an acoustic beam formed at a difference frequency generated by non-linear interaction of acoustic energy of primary frequencies. At least three primary frequencies are transmitted from a frequency source by amplifiers and acoustic projectors of the sonar. The non-linear interaction of the primary frequencies produces at least three difference frequencies. The difference frequencies are received by a receiver array. Increased interaction increases efficiency linearly with the number of primary frequencies used. The increased bandwidth resulting from the use of multiple center frequencies can also produce signal processing gains and signal-to-signal ratio is also improved, especially at the lower difference frequencies.
FILED Monday, September 28, 2015
APPL NO 14/867177
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 15/02 (20130101) Original (OR) Class
G01S 15/88 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524090 Keel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Paul Erich Keel (Cambridge, Massachusetts);  Jeffrey Huang (Lausanne, Switzerland)
ASSIGNEE(S) Paul Erich Keel (Cambridge, Massachusetts)
INVENTOR(S) Paul Erich Keel (Cambridge, Massachusetts);  Jeffrey Huang (Lausanne, Switzerland)
ABSTRACT A computer-implemented method of interacting with a plurality of arbitrary data items includes configuring each of the data items into a distinct information object by extracting, from each data item, extracted data including a heading, a source, multimedia data, and a URL. The method additionally uses the extracted data to cause display of a representation of each of the information objects in a uniform format, wherein the format includes a card, and, within the card, a multimedia window, the heading, the source, a set of indicators, and a set of icons giving graphical access to functions.
FILED Friday, March 20, 2015
APPL NO 14/664178
ART UNIT 2173 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 3/04817 (20130101)
G06F 3/04842 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524232 Bhattacharjee et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Abhishek Bhattacharjee (Princeton, New Jersey);  Margaret Martonosi (Skillman, New Jersey)
ABSTRACT A chip multiprocessor includes a plurality of cores each having a translation lookaside buffer (TLB) and a prefetch buffer (PB). Each core is configured to determine a TLB miss on the core's TLB for a virtual page address and determine whether or not there is a PB hit on a PB entry in the PB for the virtual page address. If it is determined that there is a PB hit, the PB entry is added to the TLB. If it is determined that there is not a PB hit, the virtual page address is used to perform a page walk to determine a translation entry, the translation entry is added to the TLB and the translation entry is prefetched to each other one of the plurality of cores.
FILED Friday, October 03, 2014
APPL NO 14/506203
ART UNIT 2135 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0215 (20130101) Original (OR) Class
G06F 12/0862 (20130101)
G06F 12/1009 (20130101)
G06F 12/1027 (20130101)
G06F 2212/654 (20130101)
G06F 2212/681 (20130101)
G06F 2212/682 (20130101)
G06F 2212/684 (20130101)
G06F 2212/1016 (20130101)
G06F 2212/6022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524271 Niesen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) ALCATEL-LUCENT USA INC (Murray Hill, New Jersey)
ASSIGNEE(S) Alcatel Lucent (Boulogne-Billancourt, France)
INVENTOR(S) Urs Niesen (Murray Hill, New Jersey);  Piyush Gupta (Murray Hill, New Jersey)
ABSTRACT A first source node transmits a first transmission vector formed by multiplying a vector of input values and an inverse of a transfer matrix that relates vectors transmitted from the first source node via a plurality of intermediate nodes to vectors received at a plurality of destination nodes. Each of the intermediate nodes transmits a vector formed by a linear operation performed on received vectors. The linear operation may be determined based on linear combinations of the first transmission vector and one or more second transmission vectors transmitted by second source nodes. The linear combinations are to be received at the destination nodes. The linear operation is chosen so that propagation of the first transmission vector through the intermediate nodes produces, at the destination nodes, predetermined linear combinations of the first transmission vector and one or more second transmission vectors transmitted by one or more second source nodes.
FILED Friday, January 10, 2014
APPL NO 14/152518
ART UNIT 2444 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 17/10 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524358 Rutkowski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Krzysztof J. Rutkowski (Riva, Maryland);  Stephen M. Farley (Sterling, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Krzysztof J. Rutkowski (Riva, Maryland);  Stephen M. Farley (Sterling, Virginia)
ABSTRACT Exemplary inventive practice provides initially for designation of all tasks contemplated for performance in the context of an interoperability architecture for computer modeling/simulation. Task requirements afford the bases for determining the models to be incorporated and the functionalities to be carried out in the architecture. The major architectural elements are the core, the interface, and the modules. The core is compartmentalized. Each module constitutes an individual model. Each functionality is allocated to either the core or at least one module, with the guiding principle that a functionality that characterizes the modules in general should be situated in the core, in at least one category. The interface provides for plug-and-play functionality of the modules. The architecture operates in an iterative three-phase cycle: modules write data to the core; the core processes data; modules read updated core data. The invention reduces model development, increases code reuse, and promotes interoperability of diverse models.
FILED Monday, June 10, 2013
APPL NO 13/913929
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/5009 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524462 Esser et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Steven K. Esser (San Jose, California);  Dharmendra S. Modha (San Jose, California);  Anthony Ndirango (Berkeley, California)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Steven K. Esser (San Jose, California);  Dharmendra S. Modha (San Jose, California);  Anthony Ndirango (Berkeley, California)
ABSTRACT Embodiments of the invention relate to canonical spiking neurons for spatiotemporal associative memory. An aspect of the invention provides a spatiotemporal associative memory including a plurality of electronic neurons having a layered neural net relationship with directional synaptic connectivity. The plurality of electronic neurons configured to detect the presence of a spatiotemporal pattern in a real-time data stream, and extract the spatiotemporal pattern. The plurality of electronic neurons are further configured to, based on learning rules, store the spatiotemporal pattern in the plurality of electronic neurons, and upon being presented with a version of the spatiotemporal pattern, retrieve the stored spatiotemporal pattern.
FILED Thursday, August 30, 2012
APPL NO 13/598915
ART UNIT 2122 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/049 (20130101) Original (OR) Class
G06N 3/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524464 Davulcu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Hasan Davulcu (Phoenix, Arizona);  Mark Woodward (Yogyakarta, Indonesia);  Steven Corman (Chandler, Arizona);  Jieping Ye (Phoenix, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Hasan Davulcu (Phoenix, Arizona);  Mark Woodward (Yogyakarta, Indonesia);  Steven Corman (Chandler, Arizona);  Jieping Ye (Phoenix, Arizona)
ABSTRACT Computerized contextual analysis systems and methods suitable for monitoring situations, regions, and groups characterized by volatility and uncertainty are provided. Via use of exemplary systems and methods, decision makers, for example politicians, warfighters, and analysts can gain insight into the cultures, attitudes, events, and relationships that may impact their missions.
FILED Wednesday, March 05, 2014
APPL NO 14/198212
ART UNIT 2122 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524647 Kohn-Rich
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Sylvia Kohn-Rich (Manhattan Beach, California)
ABSTRACT A flight path planning approach may be deterministic and guarantee a safe, quasi-optimal path. A plurality of three-dimensional voxels may be determined as cells of a rectangular grid. The cells may have a predetermined length and width. A shortest safe path through the grid graph may be calculated from a local start to a local goal defined as points on a nominal global path. Geometric smoothing may be performed on the basis line from the local start to the local goal to generate a smooth three-dimensional trajectory that can be followed by a given rotorcraft. Dynamic smoothing may be performed on the three-dimensional trajectory to provide a maximum possible speed profile over a path defined by the dynamic smoothing. The three dimensional path information may be provided to an autopilot, which may then control the rotorcraft to fly along the defined path.
FILED Monday, January 19, 2015
APPL NO 14/599574
ART UNIT 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 1/042 (20130101)
G05D 1/102 (20130101)
G05D 1/0808 (20130101)

Traffic Control Systems
G08G 5/0034 (20130101) Original (OR) Class
G08G 5/0047 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524730 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
ASSIGNEE(S) OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
INVENTOR(S) DeLiang Wang (Columbus, Ohio);  Yuxuan Wang (Columbus, Ohio)
ABSTRACT A system receives monaural sound which includes speech and background noises. The received sound is divided by frequency and time into time-frequency units (TFUs). Each TFU is classified as speech or non-speech by a processing unit. The processing unit for each frequency range includes at least one of a deep neural network (DNN) or a linear support vector machine (LSVM). The DNN extracts and classifies the features of the TFU and includes a pre-trained stack of Restricted Boltzmann Machines (RBM), and each RBM includes a visible and a hidden layer. The LSVM classifies each TFU based on extracted features from the DNN, including those from the visible layer of the first RBM, and those from the hidden layer of the last RBM in the stack. The LSVM and DNN include training with a plurality of training noises. Each TFU classified as speech is output.
FILED Friday, March 29, 2013
APPL NO 14/388260
ART UNIT 2658 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 21/0208 (20130101) Original (OR) Class
G10L 21/0232 (20130101)
G10L 25/30 (20130101)
G10L 2021/02087 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524767 Pileggi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Lawrence Pileggi (Pittsburgh, Pennsylvania);  David M. Bromberg (Pittsburgh, Pennsylvania);  Huseyin E. Sumbul (Pittsburgh, Pennsylvania)
ABSTRACT A method includes receiving a data bit value at a buffer in a bitcell based on a first state of a write bitline connected to the buffer, and transferring the data bit value from the buffer to a first magnetic switching cell in the bitcell for a later read operation at least by holding the write bitline to a reference value different from the first state, and asserting first and second predetermined voltage levels on respective first and second write wordlines connected to the buffer.
FILED Friday, June 20, 2014
APPL NO 14/898580
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101)
G11C 11/1673 (20130101)
G11C 11/1675 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524809 Boulais et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Kevin A. Boulais (La Plate, Maryland);  Simin Feng (Waldorf, Maryland);  Pearl Rayms-Keller (Fredericksburg, Virginia);  Michael S. Lowry (Fredericksburg, Virginia);  Francesco Santiago (Spring Hill, Florida)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Kevin A. Boulais (La Plate, Maryland);  Simin Feng (Waldorf, Maryland);  Pearl Rayms-Keller (Fredericksburg, Virginia);  Michael S. Lowry (Fredericksburg, Virginia);  Francesco Santiago (Spring Hill, Florida)
ABSTRACT A dielectric composite material is provided for switch control by optical stimulus. The material includes a plurality of photo-conductive particulates; and a transparent binder for containing the plurality of particulates to form a photo-conductive pigment based matrix. The pigment based matrix is disposed on to overlap first and second separate electrodes to produce an electrical junction. Capacitance of the pigment based matrix changes from a first value absent the optical stimulus to a second value in response to illumination at a specific electromagnetic frequency and intensity by the optical stimulus.
FILED Monday, December 07, 2015
APPL NO 14/960440
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/10 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/00 (20130101)
C09D 133/12 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 3/447 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524820 Jacobson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S) Boris S. Jacobson (Westford, Massachusetts);  Stephen R. Elkins (Franklin, Massachusetts)
ABSTRACT An apparatus includes a coil assembly, a core, and at least one cooling channel. The coil assembly includes at least one winding configured to receive a varying electrical current. The core includes multiple segments, and the at least one winding is wound around portions of the segments and is configured to generate a magnetic flux. The at least one cooling channel is configured to transport coolant through the coil assembly or core in order to cool the coil assembly or core. Portions of the segments of the core can be separated from one another to form multiple cooling channels through the core, and the multiple cooling channels can be configured to transport coolant through the core. The coil assembly may include at least one insulative spacer having multiple cooling channels, and the multiple cooling channels may be configured to transport coolant through the coil assembly.
FILED Tuesday, November 13, 2012
APPL NO 13/675092
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 27/08 (20130101)
H01F 27/24 (20130101)
H01F 27/025 (20130101) Original (OR) Class
H01F 27/2876 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49071 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525312 Scherer et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Axel Scherer (Barnard, Vermont);  Aditya Rajagopal (Irvine, California);  Seheon Kim (San Jose, California);  Andrew P. Homyk (South Pasadena, California)
ABSTRACT The present disclosure describes a method for optically powering transducers and related transducers with a photovoltaic collector. An optical fiber power delivery method and a free space power delivery method are also provided. A fabrication process for making an optically powered transducer is further described, together with an implantable transducer system based on optical power delivery.
FILED Monday, August 31, 2015
APPL NO 14/840819
ART UNIT 2636 — Optical Communications
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0017 (20130101)
A61B 5/6867 (20130101)
A61B 2560/0219 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/02 (20130101)
G01J 3/0218 (20130101)
G01J 3/0283 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/054 (20141201)
H01L 31/0475 (20141201)
H01L 31/03529 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 17/00 (20130101) Original (OR) Class

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 40/38 (20141201)

Amplifiers
H03F 3/082 (20130101)
H03F 3/45183 (20130101)
H03F 2203/45702 (20130101)

Transmission
H04B 10/807 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525330 Knaian et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Ara Knaian (Newton, Massachusetts);  Neil A. Gershenfeld (Cambridge, Massachusetts);  Maxim Lobovsky (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ara Knaian (Newton, Massachusetts);  Neil A. Gershenfeld (Cambridge, Massachusetts);  Maxim Lobovsky (Cambridge, Massachusetts)
ABSTRACT An electropermanent linear actuator has a stator, forcer, drive circuitry, and feedback control mechanism. The stator includes at least one electropermanent magnet with a coil that passes current pulses that change the magnetization of the magnet, which change persists after current is removed. The forcer moves with respect to the stator in response to the persistent changes in magnetization. Drive circuitry controls the position or speed of the actuator by controlling the timing, magnitude, and/or shape of the current pulses. The voltage and duration of pulses are of sufficient magnitude to cause the magnetization change to persist after cessation of current, with voltage and current returning substantially to zero between pulses. The feedback control mechanism determines, based on actuator velocity or position, when the next current pulse should be issued, pulse issuance being timed so that the actuator will continue to move throughout the absence of applied current between pulses.
FILED Tuesday, March 18, 2014
APPL NO 14/218797
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Dynamo-electric Machines
H02K 21/04 (20130101)
H02K 21/44 (20130101)
H02K 21/046 (20130101)
H02K 33/00 (20130101)
H02K 37/20 (20130101)
H02K 41/03 (20130101) Original (OR) Class
H02K 41/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 09522387 Biener et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Juergen Biener (San Leandro, California);  Arne Wittstock (Livermore, California);  Monika M. Biener (San Leandro, California);  Michael Bagge-Hansen (Livermore, California);  Marcus Baeumer (Bremen, Germany);  Andre Wichmann (Bremen, Germany);  Bjoern Neuman (Hamburg, Germany)
ABSTRACT In one embodiment, a system includes a nanoporous gold structure and a plurality of oxide particles deposited on the nanoporous gold structure; the oxide particles are characterized by a crystalline phase. In another embodiment, a method includes depositing oxide nanoparticles on a nanoporous gold support to form an active structure and functionalizing the deposited oxide nanoparticles.
FILED Friday, June 14, 2013
APPL NO 13/918738
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/885 (20130101)
B01D 53/945 (20130101)
B01D 2255/106 (20130101)
B01D 2255/802 (20130101)
B01D 2255/9202 (20130101)
B01D 2255/20707 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/063 (20130101)
B01J 23/10 (20130101)
B01J 23/52 (20130101)
B01J 23/66 (20130101)
B01J 23/745 (20130101)
B01J 23/8906 (20130101) Original (OR) Class
B01J 35/002 (20130101)
B01J 35/004 (20130101)
B01J 35/006 (20130101)
B01J 35/0013 (20130101)
B01J 35/1009 (20130101)
B01J 35/1014 (20130101)
B01J 35/1061 (20130101)
B01J 37/0201 (20130101)
B01J 37/0207 (20130101)
B01J 37/349 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 2203/044 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09522419 Golovashchenko
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Sergey Fedorovich Golovashchenko (Beverly Hills, Michigan)
ASSIGNEE(S) Ford Global Technologies, LLC (Dearborn, Michigan)
INVENTOR(S) Sergey Fedorovich Golovashchenko (Beverly Hills, Michigan)
ABSTRACT A method of forming a part that has areas of high strain and predicted areas of low strain from a blank and method of designing a die for forming such a part. Predicted areas of low strain are identified that are adjacent to predicted areas of high strain. A pre-forming die is designed to form the blank to provide a donor pocket in an intermediate part in a predicted low strain area that is adjacent to the predicted high strain area. The donor pocket of the intermediate part is drawn into the predicted high strain area while forming the intermediate part into the part.
FILED Friday, March 11, 2011
APPL NO 13/045878
ART UNIT 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal
B21D 22/00 (20130101)
B21D 22/24 (20130101) Original (OR) Class
B21D 37/08 (20130101)

Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 1/673 (20130101)
C21D 7/02 (20130101)
C21D 9/48 (20130101)
C21D 2221/00 (20130101)
C21D 2221/10 (20130101)

Electric Digital Data Processing
G06F 17/5018 (20130101)
G06F 2217/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523087 Aehle et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Danisco US Inc. (Palo Alto, California)
ASSIGNEE(S) DANISCO US INC (, California)
INVENTOR(S) Wolfgang Aehle (Zwingenberg, Germany);  Richard R. Bott (Burlingame, California);  Benjamin S. Bower (Newark, California);  Jonathan Caspi (Sunnyvale, California);  David A. Estell (San Francisco, California);  Frits Goedegebuur (Vlaardingen, Netherlands);  Ronaldus Wilhelmus Joannes Hommes (Haarlem, Netherlands);  Thijs Kaper (Half Moon Bay, California);  Bradley R. Kelemen (Menlo Park, California);  Slavko Kralj (Oegstgeest, Netherlands);  Johannes Franciscus Thomas Van Lieshout (Utrecht, Netherlands);  Igor Nikolaev (Noordwijk, Netherlands);  Sander Van Stigt Thans (Zevenbergen, Netherlands);  Louise Wallace (Redwood City, California);  Gudrun Vogtentanz (Sunnyvale, California);  Mats Sandgren (Uppsala, Sweden)
ABSTRACT The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
FILED Tuesday, February 25, 2014
APPL NO 14/189943
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2437 (20130101) Original (OR) Class

Enzymes
C12Y 302/01091 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523132 McKnight
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Timothy E. McKnight (Greenback, Tennessee)
ABSTRACT The present invention relates to a rapid, highly fieldable, nearly reagentless diagnostic to identify active RNA viral replication in a live, infected cells, and more particularly in leukocytes and tissue samples (including biopsies and nasal swabs) using an array of a plurality of vertically-aligned nanostructures that impale the cells and introduce a DNA reporter construct that is expressed and amplified in the presence of active viral replication.
FILED Friday, March 14, 2014
APPL NO 14/212718
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/701 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523152 Chou et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Jeffrey Brian Chou (Walnut Creek, California);  Sang-Gook Kim (Wayland, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jeffrey Brian Chou (Walnut Creek, California);  Sang-Gook Kim (Wayland, Massachusetts)
ABSTRACT A metallic-dielectric photonic crystal is formed with a periodic structure defining a plurality of resonant cavities to selectively absorb incident radiation. A metal layer is deposited on the inner surfaces of the resonant cavities and a dielectric material fills inside the resonant cavities. This photonic crystal can be used to selectively absorb broadband solar radiation and then reemit absorbed radiation in a wavelength band that matches the absorption band of a photovoltaic cell. The photonic crystal can be fabricated by patterning a sacrificial layer with a plurality of holes, into which is deposited a supporting material. Removing the rest of the sacrificial layer creates a supporting structure, on which a layer of metal is deposited to define resonant cavities. A dielectric material then fills the cavities to form the photonic crystal.
FILED Friday, September 05, 2014
APPL NO 14/478381
ART UNIT 2872 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/046 (20130101)
C23C 14/081 (20130101)
C23C 14/083 (20130101)
C23C 16/45525 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 1/113 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 10/30 (20141201)
H02S 40/44 (20141201)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523499 Siriwardane et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) Ranjani V. Siriwardane (Morgantown, West Virginia);  Hanjing Tian (Morgantown, West Virginia)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Ranjani V. Siriwardane (Morgantown, West Virginia);  Hanjing Tian (Morgantown, West Virginia)
ABSTRACT The disclosure provides an oxygen carrier for a chemical looping cycle, such as the chemical looping combustion of solid carbonaceous fuels, such as coal, coke, coal and biomass char, and the like. The oxygen carrier is comprised of at least 24 weight % (wt %) CuO, at least 10 wt % Fe2O3, and an inert support, and is typically a calcine. The oxygen carrier exhibits a CuO crystalline structure and an absence of iron oxide crystalline structures under XRD crystallography, and provides an improved and sustained combustion reactivity in the temperature range of 600° C.-1000° C. particularly for solid fuels such as carbon and coal.
FILED Tuesday, June 14, 2011
APPL NO 13/159553
ART UNIT 3749 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Burners
F23D 14/22 (20130101) Original (OR) Class
F23D 14/32 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 20/344 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523666 Roscioli et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Aerodyne Research, Inc. (Billerica, Massachusetts)
ASSIGNEE(S) Aerodyne Research, Inc. (Billerica, Massachusetts)
INVENTOR(S) Joseph R. Roscioli (Chelmsford, Massachusetts);  Scott C. Herndon (Littleton, Massachusetts);  David D. Nelson, Jr. (N. Chelmsford, Massachusetts)
ABSTRACT In one embodiment, active (continuous or intermittent) passivation may be employed to prevent interaction of sticky molecules with interfaces inside of an instrument (e.g., an infrared absorption spectrometer) and thereby improve response time. A passivation species may be continuously or intermittently applied to an inlet of the instrument while a sample gas stream is being applied. The passivation species may have a highly polar functional group that strongly binds to either water or polar groups of the interfaces, and once bound presents a non-polar group to the gas phase in order to prevent further binding of polar molecules. The instrument may be actively used to detect the sticky molecules while the passivation species is being applied.
FILED Monday, December 15, 2014
APPL NO 14/570401
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/002 (20130101)
B01J 2219/02 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 41/32 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/108 (20130101)
G01J 2003/102 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4141 (20130101)
G01N 27/4145 (20130101)
G01N 33/006 (20130101) Original (OR) Class
G01N 33/0037 (20130101)
G01N 33/0054 (20130101)
G01N 33/0062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523777 Cecil et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Argonne, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Thomas Cecil (Darien, Illinois);  Lisa Gades (Aurora, Illinois);  Antonio Miceli (Chicago, Illinois);  Orlando Quaranta (Chicago, Illinois)
ABSTRACT A microcalorimeter for radiation detection that uses superconducting kinetic inductance resonators as the thermometers. The detector is frequency-multiplexed which enables detector systems with a large number of pixels.
FILED Thursday, April 10, 2014
APPL NO 14/250083
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/1606 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524848 Hirsch
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Gregory Hirsch (Pacifica, California)
ASSIGNEE(S)
INVENTOR(S) Gregory Hirsch (Pacifica, California)
ABSTRACT A method of producing field emitters having improved brightness and durability relying on the creation of a liquid Taylor cone from electrically conductive materials having high melting points. The method calls for melting the end of a wire substrate with a focused laser beam, while imposing a high positive potential on the material. The resulting molten Taylor cone is subsequently rapidly quenched by cessation of the laser power. Rapid quenching is facilitated in large part by radiative cooling, resulting in structures having characteristics closely matching that of the original liquid Taylor cone. Frozen Taylor cones thus obtained yield desirable tip end forms for field emission sources in electron beam applications. Regeneration of the frozen Taylor cones in-situ is readily accomplished by repeating the initial formation procedures. The high temperature liquid Taylor cones can also be employed as bright ion sources with chemical elements previously considered impractical to implement.
FILED Friday, November 07, 2014
APPL NO 14/536555
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 1/3044 (20130101)
H01J 9/025 (20130101)
H01J 37/08 (20130101)
H01J 37/073 (20130101) Original (OR) Class
H01J 2201/30411 (20130101)
H01J 2237/0805 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525160 Chen et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Guoying Chen (Oakland, California);  Thomas J. Richardson (Oakland, California)
ABSTRACT This invention relates to low-cost, electroactive-polymer incorporated fine-fiber composite membranes for use as overcharge and/or overdischarge protection separators in non-aqueous electrochemical cells and the methods for making such membranes.
FILED Tuesday, May 14, 2013
APPL NO 14/400776
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/162 (20130101)
H01M 2/1686 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525176 Gschneidner, Jr. et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Karl A. Gschneidner, Jr. (Ames, Iowa);  Frederick A. Schmidt (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Karl A. Gschneidner, Jr. (Ames, Iowa);  Frederick A. Schmidt (Ames, Iowa)
ABSTRACT A carbothermic reduction method is provided for reducing a La-, Ce-, MM-, and/or Y-containing oxide in the presence of carbon and a source of a reactant element comprising Si, Ge, Sn, Pb, As, Sb, Bi, and/or P to form an intermediate alloy material including a majority of La, Ce, MM, and/or Y and a minor amount of the reactant element. The intermediate material is useful as a master alloy for in making negative electrode materials for a metal hydride battery, as hydrogen storage alloys, as master alloy additive for addition to a melt of commercial Mg and Al alloys, steels, cast irons, and superalloys; or in reducing Sm2O3 to Sm metal for use in Sm—Co permanent magnets.
FILED Thursday, January 10, 2013
APPL NO 13/694846
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys
C22C 1/00 (20130101)
C22C 28/00 (20130101)
C22C 30/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/242 (20130101)
H01M 4/383 (20130101)
H01M 4/385 (20130101)
H01M 4/662 (20130101) Original (OR) Class
H01M 10/30 (20130101)
H01M 10/345 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/124 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/54 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525181 Liu et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) LG Fuel Cell Systems Inc. (North Canton, Ohio)
ASSIGNEE(S) LG Fuel Cell Systems Inc. (North Canton, Ohio)
INVENTOR(S) Zhien Liu (Canton, Ohio);  Richard Goettler (Medina, Ohio)
ABSTRACT The present invention includes an integrated planar, series connected fuel cell system having electrochemical cells electrically connected via interconnects, wherein the anodes of the electrochemical cells are protected against Ni loss and migration via an engineered porous anode barrier layer.
FILED Friday, March 15, 2013
APPL NO 13/843422
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8621 (20130101)
H01M 4/9025 (20130101)
H01M 8/0206 (20130101)
H01M 8/0232 (20130101) Original (OR) Class
H01M 8/0236 (20130101)
H01M 8/0243 (20130101)
H01M 8/0247 (20130101)
H01M 8/0282 (20130101)
H01M 8/1286 (20130101)
H01M 8/2425 (20130101)
H01M 2008/1293 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/521 (20130101)
Y02E 60/525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525190 Wiers et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Brian M. Wiers (Berkeley, California);  Nitash P. Balsara (El Cerrito, California);  Jeffrey R. Long (Oakland, California)
ASSIGNEE(S) The Regents of The University of California (Oakland, California)
INVENTOR(S) Brian M. Wiers (Berkeley, California);  Nitash P. Balsara (El Cerrito, California);  Jeffrey R. Long (Oakland, California)
ABSTRACT Various embodiments of the invention disclose that the uptake of LiOiPr in Mg2(dobdc) (dobdc4−=1,4-dioxido-2,5-benzenedicarboxylate) followed by soaking in a typical electrolyte solution leads to a new solid lithium electrolyte Mg2(dobdc).0.35LiOiPr.0.25LiBF4.EC.DEC. Two-point ac impedance data show a pressed pellet of this material to have a conductivity of 3.1×10−4 S/cm at 300 K. In addition, the results from variable-temperature measurements reveal an activation energy of approximately 0.15 eV, while single-particle data suggest that intraparticle transport dominates conduction.
FILED Monday, March 28, 2016
APPL NO 15/083029
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/1646 (20130101)
H01M 2/1653 (20130101)
H01M 10/056 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 10/0562 (20130101)
H01M 2300/0065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525191 Liu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Tianbiao Liu (Richland, Washington);  Guosheng Li (Richland, Washington);  Jun Liu (Richland, Washington);  Yuyan Shao (Richland, Washington)
ABSTRACT Electrolytes for Mg-based energy storage devices can be formed from non-nucleophilic Mg2+ sources to provide outstanding electrochemical performance and improved electrophilic susceptibility compared to electrolytes employing nucleophilic sources. The instant electrolytes are characterized by high oxidation stability (up to 3.4 V vs Mg), improved electrophile compatibility and electrochemical reversibility (up to 100% coulombic efficiency). Synthesis of the Mg2+ electrolytes utilizes inexpensive and safe magnesium dihalides as non-nucleophilic Mg2+ sources in combination with Lewis acids, MRaX3-a (for 3≧a≧1). Furthermore, addition of free-halide-anion donors can improve the coulombic efficiency of Mg electrolytes from nucleophilic or non-nucleophilic Mg2+ sources.
FILED Tuesday, November 19, 2013
APPL NO 14/084075
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/054 (20130101)
H01M 10/0568 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525398 Olsson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Roy H. Olsson (Albuquerque, New Mexico);  Thomas A. Friedmann (Albuquerque, New Mexico);  Sara Jensen Homeijer (Albuquerque, New Mexico);  Michael Wiwi (Albuquerque, New Mexico);  Khalid Mikhiel Hattar (Albuquerque, New Mexico);  Blythe Clark (Albuquerque, New Mexico);  Todd Bauer (Albuquerque, New Mexico);  Stuart B. Van Deusen (Albuquerque, New Mexico)
ABSTRACT The present invention relates to a single crystal micromechanical resonator. In particular, the resonator includes a lithium niobate or lithium tantalate suspended plate. Also provided are improved microfabrication methods of making resonators, which does not rely on complicated wafer bonding, layer fracturing, and mechanical polishing steps. Rather, the methods allow the resonator and its components to be formed from a single crystal.
FILED Tuesday, May 27, 2014
APPL NO 14/288236
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Impedance Networks, e.g Resonant Circuits; Resonators
H03H 3/02 (20130101)
H03H 9/17 (20130101) Original (OR) Class
H03H 9/54 (20130101)
H03H 9/205 (20130101)
H03H 2003/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 09522864 Matson et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Theodore D. Matson (Goleta, California);  Peter C. Ford (Santa Barbara, California);  Gerald Macala (Santa Barbara, California);  Alexei Iretski (Sault Sainte Marie, Michigan)
ABSTRACT A method of catalytically preparing a fluid product from solid carbonaceous material is described. In the method, at least one of the following equilibria is established by one or more catalysts: a) CH3OH═CO+2H2, b) CO+H2O═CO2+H2. In some versions, the solid carbonaceous material is woody biomass. Components of the fluid product can include one or a combination of C5-C9 alcohols. In certain versions, the method can he practiced with substantially all of the carbon in the carbonaceous material being converted to the fluid product. Also, in some versions, the fluid product can be prepared with substantially no char formation. The fluid product of various versions can be used directly as fuel or as a reagent for preparing commodity chemicals without the need for separating the fluid product components.
FILED Thursday, July 03, 2014
APPL NO 14/323264
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/80 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/22 (20130101)
C01B 2203/0277 (20130101)
C01B 2203/0283 (20130101)
C01B 2203/1041 (20130101)
C01B 2203/1076 (20130101)
C01B 2203/1082 (20130101)
C01B 2203/1094 (20130101)
C01B 2203/1223 (20130101)

Acyclic or Carbocyclic Compounds
C07C 29/1518 (20130101) Original (OR) Class

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 2300/1011 (20130101)

Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases
C10J 3/00 (20130101)
C10J 2300/0916 (20130101)
C10J 2300/0986 (20130101)
C10J 2300/0989 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/02 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/18 (20130101)
Y02E 50/32 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 30/20 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523101 Rao
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Catholic University of America (Washington, District of Columbia)
ASSIGNEE(S) The Catholic University of America (Washington, District of Columbia)
INVENTOR(S) Venigalla B. Rao (Silver Spring, Maryland)
ABSTRACT Complex viruses are assembled from simple protein subunits by sequential and irreversible assembly. During genome packaging in bacteriophages, a powerful molecular motor assembles at the special portal vertex of an empty prohead to initiate packaging. An aspect of the invention relates to the phage T4 packaging machine being highly promiscuous, translocating DNA into finished phage heads as well as into proheads. Single motors can force exogenous DNA into phage heads at the same rate as into proheads and phage heads undergo repeated initiations, packaging multiple DNA molecules into the same head. This shows that the phage DNA packaging machine has unusual conformational plasticity, powering DNA into an apparently passive capsid receptacle, including the highly stable virus shell, until it is full. These features allow for the design of a novel class of nanocapsid delivery vehicles.
FILED Wednesday, July 02, 2014
APPL NO 14/322097
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/711 (20130101)
A61K 31/7088 (20130101)
A61K 47/48776 (20130101)
A61K 48/00 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 15/87 (20130101)
C12N 15/88 (20130101)
C12N 2795/10042 (20130101)
C12N 2795/10122 (20130101)
C12N 2795/10142 (20130101)
C12N 2795/10152 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523683 Kim et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents Of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Jinsang Kim (Ann Arbor, Michigan);  Jiseok Lee (Ann Arbor, Michigan)
ABSTRACT A microarray includes a solid substrate having a surface, the surface having a plurality of binding spots and a plurality of reaction moieties bound to the binding spots. A reaction moiety includes a plurality of polyacetylene monomers, the polyacetylene monomers having a first coupling region and a second coupling region, the first coupling region having a first functional group operable to bind to the binding spot and the second coupling region comprising a second functional group operable to bind to an accessory molecule; and an accessory molecule having a binding region and an analyte reaction region, the analyte reaction region operable to selectively bind to the target analyte, and the binding region operable to bind to the second coupling region of the polyacetylene monomer. Upon binding a target analyte with the reaction moiety, a color change from the polyacetylene monomer occurs and the reaction moiety produces fluorescence.
FILED Friday, January 17, 2014
APPL NO 14/157670
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/11 (20130101)

Acyclic or Carbocyclic Compounds
C07C 233/20 (20130101)
C07C 233/49 (20130101)
C07C 233/55 (20130101)
C07C 251/48 (20130101)

Heterocyclic Compounds
C07D 251/30 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/04 (20130101)
C40B 80/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/52 (20130101)
G01N 33/542 (20130101)
G01N 33/582 (20130101)
G01N 33/5432 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523925 Lin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of North Texas (Denton, Texas)
ASSIGNEE(S) UNIVERSITY OF NORTH TEXAS (Denton, Texas)
INVENTOR(S) Yuankun Lin (Lantana, Texas);  Jeffrey R. Lutkenhaus (Denton, Texas);  David George (Denton, Texas)
ABSTRACT A single reflective optical element is constructed for use in interference lithography. The single reflective optical element is generally made up of at least two, and preferably four, polished reflective strips arranged to have particular angles relative to a laser beam passing through the optical element. A laser beam passing through the optical element will be partially reflected by the reflective strips to generate additional linearly polarized beams. The additional reflected beams overlap with the central laser beam and form an interference pattern as the beams pass out of the optical element. The generated polarized beams and interference pattern can be directed onto a photosensitive material to produce photonic crystals or photonic crystal templates.
FILED Friday, August 01, 2014
APPL NO 14/449360
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/10 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/70316 (20130101) Original (OR) Class
G03F 7/70408 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524232 Bhattacharjee et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Abhishek Bhattacharjee (Princeton, New Jersey);  Margaret Martonosi (Skillman, New Jersey)
ABSTRACT A chip multiprocessor includes a plurality of cores each having a translation lookaside buffer (TLB) and a prefetch buffer (PB). Each core is configured to determine a TLB miss on the core's TLB for a virtual page address and determine whether or not there is a PB hit on a PB entry in the PB for the virtual page address. If it is determined that there is a PB hit, the PB entry is added to the TLB. If it is determined that there is not a PB hit, the virtual page address is used to perform a page walk to determine a translation entry, the translation entry is added to the TLB and the translation entry is prefetched to each other one of the plurality of cores.
FILED Friday, October 03, 2014
APPL NO 14/506203
ART UNIT 2135 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0215 (20130101) Original (OR) Class
G06F 12/0862 (20130101)
G06F 12/1009 (20130101)
G06F 12/1027 (20130101)
G06F 2212/654 (20130101)
G06F 2212/681 (20130101)
G06F 2212/682 (20130101)
G06F 2212/684 (20130101)
G06F 2212/1016 (20130101)
G06F 2212/6022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524270 Manohar et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Rajit Manohar (Ithaca, New York);  Basit R. Sheikh (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Rajit Manohar (Ithaca, New York);  Basit R. Sheikh (Ithaca, New York)
ABSTRACT Asynchronous arithmetic units including an asynchronous IEEE 754 compliant floating-point adder and an asynchronous floating point multiplier component. Arithmetic units optimized for lower power consumption and methods for optimization are disclosed.
FILED Tuesday, October 30, 2012
APPL NO 13/663970
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 7/485 (20130101)
G06F 17/10 (20130101) Original (OR) Class
G06F 2207/3864 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09524767 Pileggi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Lawrence Pileggi (Pittsburgh, Pennsylvania);  David M. Bromberg (Pittsburgh, Pennsylvania);  Huseyin E. Sumbul (Pittsburgh, Pennsylvania)
ABSTRACT A method includes receiving a data bit value at a buffer in a bitcell based on a first state of a write bitline connected to the buffer, and transferring the data bit value from the buffer to a first magnetic switching cell in the bitcell for a later read operation at least by holding the write bitline to a reference value different from the first state, and asserting first and second predetermined voltage levels on respective first and second write wordlines connected to the buffer.
FILED Friday, June 20, 2014
APPL NO 14/898580
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101)
G11C 11/1673 (20130101)
G11C 11/1675 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525117 Tansu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Nelson Tansu (Bethlehem, Pennsylvania);  Hua Tong (Allentown, Pennsylvania);  Jing Zhang (Bethlehem, Pennsylvania);  Guangyu Liu (Bethlehem, Pennsylvania);  Gensheng Huang (Bethlehem, Pennsylvania)
ASSIGNEE(S) LEHIGH UNIVERSITY (Bethlehem, Pennsylvania)
INVENTOR(S) Nelson Tansu (Bethlehem, Pennsylvania);  Hua Tong (Allentown, Pennsylvania);  Jing Zhang (Bethlehem, Pennsylvania);  Guangyu Liu (Bethlehem, Pennsylvania);  Gensheng Huang (Bethlehem, Pennsylvania)
ABSTRACT The invention is a thermoelectric device fabricated by growing a single crystal AlInN semiconductor material on a substrate, and a method of fabricating same. In a preferred embodiment, the semiconductor material is AlInN grown on and lattice-matched to a GaN template on a sapphire substrate, and the growth is performed using metalorganic vapor phase epitaxy (MOVPE).
FILED Wednesday, December 08, 2010
APPL NO 12/963136
ART UNIT 1758 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0237 (20130101)
H01L 21/0242 (20130101)
H01L 21/0254 (20130101)
H01L 21/0262 (20130101)
H01L 21/02458 (20130101)
H01L 35/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 09523097 Kang et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Byung-Guk Kang (Albany, California);  Colleen M McMahan (Sausalito, California);  Maureen C Whalen (El Cerrito, California);  Niu Dong (San Pablo, California);  Shashi Kumar (New Delhi, India)
ABSTRACT The present invention relates to transplastomic guayule plants comprising chloroplasts engineered to express the complete cytosolic mevalonic acid (MEV) pathway.
FILED Thursday, March 13, 2014
APPL NO 14/209255
ART UNIT 1662 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8207 (20130101)
C12N 15/8213 (20130101)
C12N 15/8243 (20130101)
C12N 15/8257 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP27499 Clark et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Florida Foundation Seed Producers, Inc. (Marianna, Florida)
ASSIGNEE(S) Florida Foundation Seed Producers, Inc. (Marianna, Florida)
INVENTOR(S) David G. Clark (Gainesville, Florida);  Grayson M. Clark (Gainesville, Florida)
ABSTRACT ‘UF12-73-5’ is a new coleus plant distinguished by having warm yellow-colored leaves with a fine maroon-colored margin, novel growth habit, and desirable late-flowering characteristics, as disclosed herein.
FILED Monday, June 22, 2015
APPL NO 14/545807
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/469
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP27500 Clark et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Florida Foundation Seed Producers, Inc. (Marianna, Florida)
ASSIGNEE(S) Florida Foundation Seed Producers, Inc. (Marianna, Florida)
INVENTOR(S) David G. Clark (Gainesville, Florida);  Grayson M. Clark (Gainesville, Florida)
ABSTRACT ‘UF12-74-3’ is a new coleus plant distinguished by having deep green-colored leaves with novel multi-colored patterning, and desirable growth habit and late-flowering characteristics, as disclosed herein.
FILED Monday, June 22, 2015
APPL NO 14/545808
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/469
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 09523707 Shi et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Bruker Nano, Inc. (Santa Barbara, California)
ASSIGNEE(S) Bruker Nano, Inc. (Santa Barbara, California)
INVENTOR(S) Jian Shi (Ventura, California);  Craig Prater (Goleta, California);  Ji Ma (Thousand Oaks, California);  Chanmin Su (Ventura, California)
ABSTRACT A method of operating a metrology instrument includes generating relative motion between a probe and a sample at a scan frequency using an actuator. The method also includes detecting motion of the actuator using a position sensor that exhibits noise in the detected motion, and controlling the position of the actuator using a feedback loop and a feed forward algorithm. In this embodiment, the controlling step attenuates noise in the actuator position compared to noise exhibited by the position sensor in a bandwidth of about seven times the scan frequency. Scan frequencies up to a third of the first scanner resonance frequency or greater than 300 Hz are possible.
FILED Tuesday, January 26, 2016
APPL NO 15/006974
ART UNIT 2881 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 10/04 (20130101)
G01Q 10/06 (20130101) Original (OR) Class
G01Q 10/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525032 Slack et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Glen A. Slack (Scotia, New York);  Leo J. Schowalter (Latham, New York)
ASSIGNEE(S) CRYSTAL IS, INC. (Green Island, New York)
INVENTOR(S) Glen A. Slack (Scotia, New York);  Leo J. Schowalter (Latham, New York)
ABSTRACT Fabrication of doped AlN crystals and/or AlGaN epitaxial layers with high conductivity and mobility is accomplished by, for example, forming mixed crystals including a plurality of impurity species and electrically activating at least a portion of the crystal.
FILED Wednesday, March 26, 2014
APPL NO 14/225999
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 23/00 (20130101)
C30B 29/403 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/2003 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525148 Kazlas et al.
FUNDED BY
Central Intelligence Agency (CIA)
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S) Peter T. Kazlas (Sudbury, Massachusetts);  Zhaoqun Zhou (Allston, Massachusetts);  Yuhua Niu (Waltham, Massachusetts);  Sang-Jin Kim (Belmont, Massachusetts);  Benjamin S. Mashford (Essendon, Australia)
ASSIGNEE(S) QD VISION, INC. (Lexington, Massachusetts)
INVENTOR(S) Peter T. Kazlas (Sudbury, Massachusetts);  Zhaoqun Zhou (Allston, Massachusetts);  Yuhua Niu (Waltham, Massachusetts);  Sang-Jin Kim (Belmont, Massachusetts);  Benjamin S. Mashford (Essendon, Australia)
ABSTRACT A device including an emissive material comprising quantum dots is disclosed. In one embodiment, the device includes a first electrode and a second electrode, a layer comprising quantum dots disposed between the first electrode and the second electrodes, and a first interfacial layer disposed at the interface between a surface of the layer comprising quantum dots and a first layer in the device. In certain embodiments, a second interfacial layer is optionally further disposed on the surface of the layer comprising quantum dots opposite to the first interfacial layer. In certain embodiments, a device comprises a light-emitting device. Other light emitting devices and methods are disclosed.
FILED Friday, April 06, 2012
APPL NO 13/441394
ART UNIT 2823 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/50 (20130101) Original (OR) Class
H01L 51/502 (20130101)
H01L 51/5048 (20130101)
H01L 51/5072 (20130101)
H01L 51/5088 (20130101)
H01L 2251/552 (20130101)
H01L 2251/5369 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 09523577 Tucker
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Dennis Stephen Tucker (Huntsville, Alabama)
ABSTRACT A vibrating gyroscope includes a piezoelectric strip having length and width dimensions. The piezoelectric strip includes a piezoelectric material and carbon nanotubes (CNTs) substantially aligned and polled along the strip's length dimension. A spindle having an axis of rotation is coupled to the piezoelectric strip. The axis of rotation is parallel to the strip's width dimension. A first capacitance sensor is mechanically coupled to the spindle for rotation therewith. The first capacitance sensor is positioned at one of the strip's opposing ends and is spaced apart from one of the strip's opposing faces. A second capacitance sensor is mechanically coupled to the spindle for rotation therewith. The second capacitance sensor is positioned at another of the strip's opposing ends and is spaced apart from another of the strip's opposing faces. A voltage source applies an AC voltage to the piezoelectric strip.
FILED Thursday, February 27, 2014
APPL NO 14/192350
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 19/56 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09523768 Rincon
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Rafael F. Rincon (Greenbelt, Maryland)
ABSTRACT A method according to an illustrative embodiment includes generating first, second, third, and fourth signals. The method also includes transmitting from an antenna, the first signal, and transmitting the antenna, the second signal. The first and second signals are configured such that when the signals are transmitted simultaneously the signals constructively interact to form a first beam signal. The first beam signal has a first look angle. The method also includes transmitting from the antenna the third signal and from the antenna the fourth signal. The third and fourth signals are configured such that when the signals are transmitted simultaneously the signals constructively interact to form a second beam signal. The second beam signal has a second look angle. The method also includes receiving a first and second reflected signals and generating an interferogram utilizing information in the first and second reflected signals.
FILED Tuesday, September 30, 2014
APPL NO 14/501456
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/9023 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/0081 (20130101)
G06T 2207/10044 (20130101)
G06T 2207/30181 (20130101)
G06T 2207/30232 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 09522156 Freeman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
U.S. State Government
State of Oregon
APPLICANT(S) The UAB Research Foundation (Birmingham, Alabama);  State of Oregon Acting By and Through the Board of Education on Behalf of the University of Oregon (Eugene, Oregon);  University College Cardiff Consultants Limited (Cardiff, United Kingdom);  Morehouse School of Medicine, Inc. (Atlanta, Georgia)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama);  The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon (Eugen, Oregon);  University College Cardiff Consultants Limited (Cardiff, United Kingdom);  Morehouse School of Medicine, Inc. (Atlanta, Georgia)
INVENTOR(S) Bruce A. Freeman (Pittsburgh, Pennsylvania);  Francisco Schopfer (Pittsburgh, Pennsylvania);  Valerie O'Donnell (Penarth, United Kingdom);  Paul Baker (Pittsburgh, Pennsylvania);  Yuqing E. Chen (Ann Arbor, Michigan);  Bruce Branchaud (Eugene, Oregon)
ABSTRACT Described herein are nitrated lipids and methods of making and using the nitrated lipids.
FILED Wednesday, February 10, 2016
APPL NO 15/040376
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/21 (20130101)
A61K 31/201 (20130101)
A61K 31/202 (20130101)
A61K 31/575 (20130101) Original (OR) Class
A61K 45/06 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 43/02 (20130101)

Acyclic or Carbocyclic Compounds
C07C 205/03 (20130101)
C07C 205/50 (20130101)
C07C 205/51 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US D774408 Rymer et al.
FUNDED BY
Department of Transportation (USDOT)
U.S. State Government
State of California
California Department of Transportation (CALTRANS)
APPLICANT(S) State of California, Department of Transportation (Sacramento, California)
ASSIGNEE(S)
INVENTOR(S) Bruce C. Rymer (Sacramento, California);  Paul R. Donavan (Petaluma, California)
ABSTRACT
FILED Friday, October 02, 2015
APPL NO 29/541381
ART UNIT 2913 — Design
CURRENT CPC
Measuring, testing, or signalling instruments
D10/113.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Central Intelligence Agency (CIA) 

US 09525148 Kazlas et al.
FUNDED BY
Central Intelligence Agency (CIA)
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S) Peter T. Kazlas (Sudbury, Massachusetts);  Zhaoqun Zhou (Allston, Massachusetts);  Yuhua Niu (Waltham, Massachusetts);  Sang-Jin Kim (Belmont, Massachusetts);  Benjamin S. Mashford (Essendon, Australia)
ASSIGNEE(S) QD VISION, INC. (Lexington, Massachusetts)
INVENTOR(S) Peter T. Kazlas (Sudbury, Massachusetts);  Zhaoqun Zhou (Allston, Massachusetts);  Yuhua Niu (Waltham, Massachusetts);  Sang-Jin Kim (Belmont, Massachusetts);  Benjamin S. Mashford (Essendon, Australia)
ABSTRACT A device including an emissive material comprising quantum dots is disclosed. In one embodiment, the device includes a first electrode and a second electrode, a layer comprising quantum dots disposed between the first electrode and the second electrodes, and a first interfacial layer disposed at the interface between a surface of the layer comprising quantum dots and a first layer in the device. In certain embodiments, a second interfacial layer is optionally further disposed on the surface of the layer comprising quantum dots opposite to the first interfacial layer. In certain embodiments, a device comprises a light-emitting device. Other light emitting devices and methods are disclosed.
FILED Friday, April 06, 2012
APPL NO 13/441394
ART UNIT 2823 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/50 (20130101) Original (OR) Class
H01L 51/502 (20130101)
H01L 51/5048 (20130101)
H01L 51/5072 (20130101)
H01L 51/5088 (20130101)
H01L 2251/552 (20130101)
H01L 2251/5369 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 09524393 Aggarwal et al.
FUNDED BY
Department of Justice (DOJ)
Office of Justice Programs (OJP)
National Institute of Justice (NIJ)
APPLICANT(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S) Sudhir Aggarwal (Tallahassee, Florida);  Shiva Houshmand Yazdi (Tallahassee, Florida);  Charles Matt Weir (Tallahassee, Florida)
ABSTRACT A system for analyzing and modifying passwords in a manner that provides a user with a strong and usable/memorable password. The user would propose a password that has relevance and can be remembered. The invention would evaluate the password to ascertain its strength. The evaluation is based on a probabilistic password cracking system that is trained on sets of revealed passwords and that can generate password guesses in highest probability order. If the user's proposed password is strong enough, the proposed password is accepted. If the user's proposed password is not strong enough, the system will reject it. If the proposed password is rejected, the system modifies the password and suggests one or more stronger passwords. The modified passwords would have limited modifications to the proposed password. Thus, the user has a tested strong and memorable password.
FILED Wednesday, April 30, 2014
APPL NO 14/266277
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/46 (20130101)
G06F 21/604 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US D774408 Rymer et al.
FUNDED BY
Department of Transportation (USDOT)
U.S. State Government
State of California
California Department of Transportation (CALTRANS)
APPLICANT(S) State of California, Department of Transportation (Sacramento, California)
ASSIGNEE(S)
INVENTOR(S) Bruce C. Rymer (Sacramento, California);  Paul R. Donavan (Petaluma, California)
ABSTRACT
FILED Friday, October 02, 2015
APPL NO 29/541381
ART UNIT 2913 — Design
CURRENT CPC
Measuring, testing, or signalling instruments
D10/113.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 09523080 Trisler et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) University of Maryland, Baltimore (Baltimore, Maryland);  The United States as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) G. David Trisler (Chevy Chase, Maryland);  Christopher T. Bever, Jr. (Glen Arm, Maryland);  James E. Goolsby (Ellicott City, Maryland);  Bernard M. Pessac (Paris, France)
ABSTRACT The present invention relates to methods and compositions concerning isolation of proliferating cells. In particular, the invention regards enrichment of stem cells in a mixture of stem cells and non-stem cells, wherein the non-stem cells may be differentiated cells. The invention exploits the non-adherent property of stem cells, as opposed to the adherent property of differentiating cells, by serially passaging the suspended cells in liquid media.
FILED Wednesday, January 07, 2015
APPL NO 14/591819
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/28 (20130101)
A61K 2035/124 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0647 (20130101)
C12N 5/0662 (20130101) Original (OR) Class
C12N 2500/30 (20130101)
C12N 2500/44 (20130101)
C12N 2500/90 (20130101)
C12N 2501/23 (20130101)
C12N 2501/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 09522350 Tzipori et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Environmental Protection Agency (EPA)
APPLICANT(S) TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts);  HAEMONETICS CORPORATION (Braintree, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts);  Haemonetics Corporation (Braintree, Massachusetts)
INVENTOR(S) Saul Tzipori (Shrewsbury, Massachusetts);  Udi Zukerman (Brookline, Massachusetts);  Gary Stacey (Marshfield, Massachusetts)
ABSTRACT A method for the simultaneous concentration of multiple toxins from large volumes of water. The method includes the steps of providing a disposable separation centrifuge bowl, the centrifuge bowl including a positively charged material at it's inner core. A large water sample contaminated with toxins from a group consisting of protozoa, bacteria, bacterial spores, and toxins is delivered to the centrifuge bowl. A centrifugal force is applied to the separation bowl. The water sample is concentrated to remove large particles of the toxins in the bowl due to the centrifugal forces. The concentrated water sample is passes through the positively charged inner core to capture any remaining concentrated targets by electrostatic forces and the concentrated targets are eluted.
FILED Wednesday, November 13, 2013
APPL NO 14/079325
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Separation
B01D 21/262 (20130101) Original (OR) Class
B01D 21/302 (20130101)
B01D 2221/10 (20130101)

Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields
B03C 3/15 (20130101)
B03C 5/02 (20130101)
B03C 2201/26 (20130101)

Centrifuges
B04B 5/10 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4077 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 09525866 Charlton et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S) Sarah T. Charlton (Frederick, Maryland);  Carla D. Martin (, None)
ABSTRACT A method of identifying a digital camera is disclosed. First and second digital images generated by the camera have dimensions that are not equal. The method includes calculating noise residuals and normalized cross-correlations (NCCs) between the noise residuals corresponding to candidate translations. The method further includes calculating a noise floor and identifying first and second peak values corresponding to translations. The method further includes calculating a peak ratio, determining that the peak ratio exceeds an alignment threshold and calculating a digital camera fingerprint for the digital camera based on the noise residuals and the first translation. The method further includes receiving a digital image, calculating a noise residual of the digital image, and determining that the image was generated by the digital camera based on the noise residual and the fingerprint and generating a record associating the image with the camera.
FILED Monday, April 18, 2016
APPL NO 15/131192
ART UNIT 2422 — Cable and Television
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/002 (20130101)

Pictorial Communication, e.g Television
H04N 17/004 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 09522179 Dinarello et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Non-Profit Organization (NPO)
American Heart Association (AHA)
Juvenile Diabetes Research Foundation (JDRF)
APPLICANT(S) Charles A. Dinarello (Boulder, Colorado);  Antonio Abbate (Glen Allen, Virginia);  Eli C. Lewis (Be'er Sheva, Israel)
ASSIGNEE(S) VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia);  THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
INVENTOR(S) Charles A. Dinarello (Boulder, Colorado);  Antonio Abbate (Glen Allen, Virginia);  Eli C. Lewis (Be'er Sheva, Israel)
ABSTRACT Embodiments herein report methods and compositions for treating cardiac conditions. In certain embodiments, compositions and methods relate to reducing, inhibiting or treating a subject having or suspected of undergoing cardiac remodeling after a cardiac event. Other embodiments herein relate to compounds including naturally occurring and synthetic compositions of alpha-1 antitrypsin and fragments thereof.
FILED Friday, March 04, 2011
APPL NO 13/582724
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/57 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 09524767 Pileggi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Lawrence Pileggi (Pittsburgh, Pennsylvania);  David M. Bromberg (Pittsburgh, Pennsylvania);  Huseyin E. Sumbul (Pittsburgh, Pennsylvania)
ABSTRACT A method includes receiving a data bit value at a buffer in a bitcell based on a first state of a write bitline connected to the buffer, and transferring the data bit value from the buffer to a first magnetic switching cell in the bitcell for a later read operation at least by holding the write bitline to a reference value different from the first state, and asserting first and second predetermined voltage levels on respective first and second write wordlines connected to the buffer.
FILED Friday, June 20, 2014
APPL NO 14/898580
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101)
G11C 11/1673 (20130101)
G11C 11/1675 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 09523726 Heumphreus et al.
FUNDED BY
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Paul R. Heumphreus (St. Peters, Missouri);  William J. Harper (Troy, Illinois);  Jeffrey D. Martin (O'Fallon, Missouri);  Edward H. Wooldridge (Farmington, Missouri);  Martha J. Molander (St. Charles, Missouri)
ABSTRACT A radio frequency (RF) reflecting apparatus includes a curved reflecting element and resistive material coupled to the curved reflecting element proximate two or more edges of the curved reflecting element. The resistive material has a first portion with a first conductance and a second portion with a second conductance that differs from the first conductance. The RF reflecting apparatus also includes a frame coupled to the curved reflecting element and at least one wheel coupled to the frame. The at least one wheel is configured to enable to translation of the curved reflecting member.
FILED Friday, July 18, 2014
APPL NO 14/335748
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 29/0814 (20130101)
G01R 29/0835 (20130101) Original (OR) Class
G01R 31/008 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/20 (20130101)
H01Q 15/14 (20130101)
H01Q 17/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09525418 Snider et al.
FUNDED BY
APPLICANT(S) Honeywell International Inc. (Morristown, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S) Daniel Walter Snider (Tampa, Florida);  Malmaruhan Sivaprakasam (Tampa, Florida);  Jeremy S. Parks (Seminole, Florida)
ABSTRACT A biasing circuit includes a differential communication line comprising a first signal line and a second signal line. The biasing circuit further includes a first current source coupled between a power supply and the first signal line. The biasing circuit further includes a first high-precision voltage reference coupled to the first current source, wherein the first high-precision voltage reference outputs a reference voltage that drives a current produced by the first current source. The biasing circuit further includes a second current source coupled to the second signal line and a system ground, wherein the second current source is driven by a voltage supplied by the power supply.
FILED Monday, March 30, 2015
APPL NO 14/673542
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 3/011 (20130101)
H03K 19/007 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, December 20, 2016.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2016/fedinvent-patents-20161220.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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