FedInvent™ Patents
Patent Details for Tuesday, December 27, 2016
This page was updated on Monday, March 27, 2023 at 04:55 AM GMT
Department of Health and Human Services (HHS)
US 09526458 | MacAuslan |
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FUNDED BY |
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APPLICANT(S) | Speech Technology and Applied Research Corporation (Bedford, Massachusetts) |
ASSIGNEE(S) | Speech Technology and Applied Research Corporation (Bedford, Massachusetts) |
INVENTOR(S) | Joel MacAuslan (Nashua, New Hampshire) |
ABSTRACT | A computer-implemented method comprises: (A) receiving first acoustic data representing a first cough train of a first human subject, wherein the first cough train comprises at least one first cough of the first human subject; (B) identifying at least one first value of at one first acoustic property of the first acoustic data; and (C) determining, based on the at least one first value of the at least one first acoustic property, whether the first acoustic data indicates that the first human subject has a severe respiratory illness. |
FILED | Thursday, April 17, 2014 |
APPL NO | 14/255436 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0823 (20130101) A61B 5/7282 (20130101) Original (OR) Class A61B 7/003 (20130101) A61B 7/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526476 | Schwartz et al. |
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APPLICANT(S) | Benjamin M. Schwartz (Seattle, Washington); Nathan J. McDannold (Jamaica Plain, Massachusetts) |
ASSIGNEE(S) | Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Benjamin M. Schwartz (Seattle, Washington); Nathan J. McDannold (Jamaica Plain, Massachusetts) |
ABSTRACT | A system and method for tracking the position of a region in a subject using an ultrasound system is provided. Training data that indicates the position of the region is acquired from the subject while ultrasound data is acquired from the subject using the ultrasound system. A position mapping table is formed using the training data and ultrasound data; this table relates position information contained in the training data to the acquired ultrasound data. The position of the region is tracked by acquiring additional ultrasound data from the subject using the ultrasound system. This additional ultrasound data is compared to the ultrasound data contained in the position mapping table to identify the position of the region based on a unique relationship between the position of the region and ultrasound echo signatures of the ultrasound data acquired in both the training and motion tracking stages. |
FILED | Tuesday, April 10, 2012 |
APPL NO | 14/111073 |
ART UNIT | 3777 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/055 (20130101) A61B 5/113 (20130101) A61B 5/0555 (20130101) A61B 5/721 (20130101) A61B 5/1126 (20130101) A61B 5/6892 (20130101) A61B 8/08 (20130101) A61B 8/085 (20130101) A61B 8/4236 (20130101) A61B 8/4416 (20130101) A61B 8/5276 (20130101) Original (OR) Class A61B 2562/164 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526693 | Rana |
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APPLICANT(S) | Tariq M. Rana (San Diego, California) |
ASSIGNEE(S) | Sanford-Burnham Medical Research Inslilute (La Jolla, California) |
INVENTOR(S) | Tariq M. Rana (San Diego, California) |
ABSTRACT | Provided are compositions and methods for delivery of therapeutic agents, such as chemically stabilized antisense oligonucleotides useful in RNA silencing. The compositions include interfering nanoparticles (iNOPs) associated with one or more agents. Several functional iNOP derivatives are provided which allow for targeted delivery of agents to specific cell types as well as exhibiting reduced cellular toxicity. |
FILED | Wednesday, March 16, 2011 |
APPL NO | 13/049825 |
ART UNIT | 1675 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Original (OR) Class A61K 47/48038 (20130101) A61K 47/48092 (20130101) A61K 47/48323 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 2810/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526702 | von Andrian et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
INVENTOR(S) | Ulrich H. von Andrian (Chestnut Hill, Massachusetts); Omid C. Farokhzad (Waban, Massachusetts); Robert S. Langer (Newton, Massachusetts); Tobias Junt (Schorndorf, Germany); Elliott Ashley Moseman (Jamaica Plain, Massachusetts); Liangfang Zhang (San Diego, California); Pamela Basto (Cambridge, Massachusetts); Matteo Iannacone (Milan, Italy); Frank Alexis (Greenville, South Carolina) |
ABSTRACT | The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at last one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/844258 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 47/48815 (20130101) A61K 47/48915 (20130101) A61K 2039/60 (20130101) A61K 2039/555 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526712 | Orlow et al. |
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APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Seth J. Orlow (New York, New York); Amitabha Mazumder (East Setauket, New York); Nicole Doudican (New York, New York) |
ABSTRACT | Screening assays and methods of using same for screening to identify modulator agents or compounds that target endoplasmic reticulum stress related signaling pathways to induce apoptosis are described herein. Pharmaceutical compositions comprising modulator agents or compounds identified by screening assays described herein are also encompassed. Methods for treating a myeloproliferative disorder characterized by monoclonal plasma cell proliferation in a subject using the aforementioned modulator agents or compounds are also envisioned. Modulator agents or compounds thereof for use in treating a myeloproliferative disorder in a subject and use of modulator agents or compounds thereof in the preparation of medicaments for the treatment of a myeloproliferative disorder are also encompassed herein. Exemplary myeloproliferative disorders include: monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and multiple myeloma (MM). |
FILED | Tuesday, February 25, 2014 |
APPL NO | 14/769888 |
ART UNIT | 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/17 (20160801) A23L 33/175 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/308 (20130101) A23V 2250/06 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/198 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 323/58 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526737 | Parhami et al. |
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APPLICANT(S) | Farhad Parhami (Los Angeles, California); Michael E. Jung (Los Angeles, California); Khanhlinh Nguyen (Los Angeles, California); Dongwon Yoo (Los Angeles, California); Woo-Kyun Kim (Los Angeles, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Farhad Parhami (Los Angeles, California); Michael E. Jung (Los Angeles, California); Khanhlinh Nguyen (Los Angeles, California); Dongwon Yoo (Los Angeles, California); Woo-Kyun Kim (Los Angeles, California) |
ABSTRACT | Synthetic oxysterols can be made and can be used for the treatment of bone disorders, obesity, cardiovascular disorders, and neurological disorders. |
FILED | Wednesday, December 03, 2008 |
APPL NO | 12/745888 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Original (OR) Class A61K 31/575 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526739 | Liang et al. |
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APPLICANT(S) | University of Connecticut (Farmington, Connecticut); The United States of America as Represented by the Secretary Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
INVENTOR(S) | Bruce Liang (Avon, Connecticut); Kenneth A. Jacobson (Silver Spring, Maryland) |
ABSTRACT | Phosphonate and phosphinate N-methanocarba derivatives of AMP including their prodrug analogs are described. MRS2339, a 2-chloro-AMP derivative containing a (N)-methanocarba (bicyclo[3.1.0]hexane) ring system in place of ribose, activates P2X receptors, ligand-gated ion channels. Phosphonate analogues of MRS2339 were synthesized using Michaelis-Arbuzov and Wittig reactions, based on the expectation of increased half-life in vivo due to the stability of the C—P bond. When administered to calsequestrin-overexpressing mice (a genetic model of heart failure) via a mini-osmotic pump (Alzet), some analogues significantly increased intact heart contractile function in vivo, as assessed by echocardiography-derived fractional shortening (FS) as compared to vehicle-infused mice. The range of carbocyclic nucleotide analogues for treatment of heart failure has been expanded. |
FILED | Thursday, February 18, 2016 |
APPL NO | 15/046630 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) Original (OR) Class A61K 31/683 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65616 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526740 | Franz et al. |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Katherine J. Franz (Durham, North Carolina); Dennis J. Thiele (Chapel Hill, North Carolina); Marian Helsel (Durham, North Carolina); Richard Festa (North Chesterfield, Virginia) |
ABSTRACT | The present disclosure provides methods of treating (including ameliorating and/or preventing) pathogenic infections by administering a therapeutically effective amount of a prochelator. The present disclosure further provides pharmaceutical compositions and a kit comprising the prochelator therein. |
FILED | Friday, April 08, 2016 |
APPL NO | 15/094349 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/69 (20130101) Original (OR) Class A61K 31/435 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526748 | Centanni et al. |
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APPLICANT(S) | STRATATECH CORPORATION (Madison, Wisconsin) |
ASSIGNEE(S) | STRATATECH CORPORATION (Madison, Wisconsin) |
INVENTOR(S) | John M. Centanni (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin) |
ABSTRACT | The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides. |
FILED | Friday, July 18, 2014 |
APPL NO | 14/335534 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/36 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 38/1825 (20130101) A61K 2035/122 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/60 (20130101) A61L 27/3813 (20130101) A61L 27/3895 (20130101) A61L 2300/252 (20130101) A61L 2300/404 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0629 (20130101) C12N 5/0698 (20130101) C12N 15/63 (20130101) C12N 15/79 (20130101) C12N 2501/117 (20130101) C12N 2501/998 (20130101) C12N 2502/094 (20130101) C12N 2502/1323 (20130101) C12N 2510/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526758 | Tuszynski et al. |
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APPLICANT(S) | Temple University of the Commonwealth of Higher Education (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Temple University-of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
INVENTOR(S) | George P. Tuszynski (Pittsgrove, New Jersey); John F. Wong (Los Angeles, California); Taffy Williams (Concord, North Carolina) |
ABSTRACT | Methods are presented for the therapeutic administration of angiocidin in the treatment of cancers such as glioma, breast cancer, and leukemia. Methods are also presented for inducing growth arrest and/or apoptosis of tumor cells, as well as inducing differentiation of tumor cells to inhibit tumorigenicity and to confer a non-tumor or healthy phenotype. |
FILED | Friday, October 24, 2014 |
APPL NO | 14/522750 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 38/185 (20130101) A61K 38/1709 (20130101) A61K 38/1808 (20130101) A61K 38/1825 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526762 | Hartgerink et al. |
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APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
INVENTOR(S) | Jeffrey Dale Hartgerink (Pearland, Texas); Vivek Ashok Kumar (Houston, Texas) |
ABSTRACT | The present disclosure provides a composition comprising a multi-domain peptide capable of self-assembly into a nanofibrous hydrogel structure capable of stimulating a robust angiogenic response. In one embodiment, the composition comprises a short 15 amino acid VEGF-165 peptide mimic conjugated to a 16 amino acid multidomain peptide. A method for promoting angiogenesis and/or treating ischemic wounds in a subject is also provided. |
FILED | Friday, August 08, 2014 |
APPL NO | 14/454802 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 38/1891 (20130101) Original (OR) Class A61K 47/48246 (20130101) A61K 47/48338 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526765 | Ponnapakkam et al. |
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APPLICANT(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas); The Kitasato Institute (Tokyo, Japan); MONTEFIORE MEDICAL CENTER (New York, New York) |
ASSIGNEE(S) | The Kitasato Institute (, Japan); Montefiore Medical Center (, None); The Board of Trustees of the University of Arkansas (, None) |
INVENTOR(S) | Tulasi Ponnapakkam (New York, New York); Sagaya Theresa Leena Philominathan (Cheshire, Connecticut); Joshua Sakon (Fayetteville, Arkansas); Ranjitha Katikaneni (New York, New York); Takaki Koide (Tokyo, Japan); Osamu Matsushita (Kanagawa, Japan); Robert C. Gensure (New York, New York) |
ABSTRACT | Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided. |
FILED | Monday, February 11, 2013 |
APPL NO | 14/378067 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/29 (20130101) Original (OR) Class A61K 38/48 (20130101) A61K 47/48246 (20130101) Enzymes C12Y 304/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526772 | Rikihisa et al. |
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APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
INVENTOR(S) | Yasuko Rikihisa (Worthington, Ohio); Dipu Mohan-Kumar (Columbus, Ohio) |
ABSTRACT | Disclosed are vaccines containing one or more immunogenic polypeptides derived from an EtpE protein from an Ehrlichia sp. or nucleic acid encoding these polypeptides. Also disclosed is a method for vaccinating a subject against Ehrlichia sp. that involves administering to the subject a composition comprising any of the disclosed vaccines. Also disclosed is a method for diagnosing and/or monitoring the treatment of Ehrlichiosis in a subject that comprising assaying a biological sample (e.g., blood, serum, or plasma sample) from the subject for the presence of an antibody that specifically binds an EtpE polypeptide. Also disclosed are methods for delivering a therapeutic or diagnostic agent to a cell in a subject that involves conjugating the agent, or a delivery vehicle comprising the agent, to polypeptide containing the C-terminal domain of an EtpE protein. |
FILED | Tuesday, December 03, 2013 |
APPL NO | 14/649138 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0233 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 47/4833 (20130101) Peptides C07K 14/29 (20130101) C07K 2319/80 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526777 | Sullivan et al. |
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APPLICANT(S) | Nancy J. Sullivan (Kensington, Maryland); Gary J. Nabel (Washington, District of Columbia); Clement Asiedu (Olney, Maryland); Cheng Cheng (Rockville, Maryland); Alfredo Nicosia (Rome, Italy); Riccardo Cortese (Rome, Italy); Virginia Ammendola (Naples, Italy); Stefano Colloca (Rome, Italy) |
ASSIGNEE(S) | The United States of America as Represented by the Department of Health and Human Services (Washington, District of Columbia); Glaxosmithkline Biologicals SA (Rixensart, Belgium) |
INVENTOR(S) | Nancy J. Sullivan (Kensington, Maryland); Gary J. Nabel (Washington, District of Columbia); Clement Asiedu (Olney, Maryland); Cheng Cheng (Rockville, Maryland); Alfredo Nicosia (Rome, Italy); Riccardo Cortese (Rome, Italy); Virginia Ammendola (Naples, Italy); Stefano Colloca (Rome, Italy) |
ABSTRACT | This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebola virus (EBOV) or Marburg virus (MARV). |
FILED | Friday, April 15, 2011 |
APPL NO | 13/641655 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/10343 (20130101) C12N 2760/14134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526784 | Liu et al. |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | David R. Liu (Lexington, Massachusetts); John Anthony Zuris (Cambridge, Massachusetts); David B. Thompson (Cambridge, Massachusetts) |
ABSTRACT | Compositions, methods, strategies, kits, and systems for the supercharged protein-mediated delivery of functional effector proteins into cells in vivo, ex vivo, or in vitro are provided. Compositions, methods, strategies, kits, and systems for delivery of funcational effector proteins using cationic lipids and cationic polymers are also provided. Functional effector proteins include, without limitation, transcriptional modulators (e.g., repressors or activators), recombinases, nucleases (e.g., RNA-programmable nucleases, such as Cas9 proteins; TALE nuclease, and zinc finger nucleases), deaminases, and other gene modifying/editing enzymes. Functional effector proteins include TALE effector proteins, e.g., TALE transcriptional activators and repressors, as well as TALE nucleases. Compositions, methods, strategies, and systems for the delivery of functional effector proteins into cells is useful for therapeutic and research purposes, including, but not limited to, the targeted manipulation of a gene associated with disease, the modulation of the expression level of a gene associated with disease, and the programming of cell fate. |
FILED | Monday, August 18, 2014 |
APPL NO | 14/462163 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/45 (20130101) A61K 38/465 (20130101) A61K 38/1767 (20130101) A61K 47/12 (20130101) Original (OR) Class Peptides C07K 14/00 (20130101) C07K 14/195 (20130101) C07K 14/463 (20130101) C07K 14/4702 (20130101) C07K 14/43595 (20130101) C07K 2319/60 (20130101) C07K 2319/80 (20130101) C07K 2319/85 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 9/1241 (20130101) Enzymes C12Y 207/07 (20130101) C12Y 301/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526786 | Landry et al. |
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APPLICANT(S) | Donald W. Landry (New York, New York); James H. Woods (Ann Arbor, Michigan); Roger K. Sunahara (Ann Arbor, Michigan); Diwahar L. Narasimhan (Ann Arbor, Michigan); Joanne MacDonald (New York, New York); Milan N. Stojanovic (Fort Lee, New Jersey); John J. Tesmer (Ann Arbor, Michigan); Remy L. Brim (Farmington Hills, Michigan) |
ASSIGNEE(S) | The Trustee of Columbia University in the City of New York (New York, New York); The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Donald W. Landry (New York, New York); James H. Woods (Ann Arbor, Michigan); Roger K. Sunahara (Ann Arbor, Michigan); Diwahar L. Narasimhan (Ann Arbor, Michigan); Joanne MacDonald (New York, New York); Milan N. Stojanovic (Fort Lee, New Jersey); John J. Tesmer (Ann Arbor, Michigan); Remy L. Brim (Farmington Hills, Michigan) |
ABSTRACT | Provided are compositions comprising a cocaine esterase (CocE) and a compound that thermostabilizes the CocE. Also provided are methods of thermostabilizing a cocaine esterase. Additionally provided are methods of treating a mammal undergoing a cocaine-induced condition. Methods of determining whether a compound is a thermostabilizing agent for a protein are also provided. Uses of the above-described compositions for the treatment of a cocaine-induced condition is additionally provided. Additionally provided is an isolated nucleic acid encoding a CocE polypeptide having the substitutions L169K and G173Q, and the CocE polypeptide encoded by that nucleic acid, and pharmaceutical compositions thereof. Further provided is the use of that composition for the manufacture of a medicament for the treatment of a cocaine-induced condition and for the treatment of a cocaine-induced condition. |
FILED | Tuesday, January 28, 2014 |
APPL NO | 14/166619 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 38/465 (20130101) A61K 38/465 (20130101) A61K 45/06 (20130101) A61K 47/12 (20130101) A61K 47/18 (20130101) A61K 47/22 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/18 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) Enzymes C12Y 301/01084 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/918 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526794 | Rangaramanujam et al. |
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APPLICANT(S) | Kannan Rangaramanujam (Detroit, Michigan); Sujatha Kannan (Detroit, Michigan); Roberto Romero (Detroit, Michigan); Raghavendra Navath (Somerset, New Jersey); Anupa Menjoge (Hayward, California) |
ASSIGNEE(S) | Wayne State University (Detroit, Michigan); National Institutes of Health (Bethesda, Maryland) |
INVENTOR(S) | Kannan Rangaramanujam (Detroit, Michigan); Sujatha Kannan (Detroit, Michigan); Roberto Romero (Detroit, Michigan); Raghavendra Navath (Somerset, New Jersey); Anupa Menjoge (Hayward, California) |
ABSTRACT | The invention discloses injectable hydrogels which are in the form of crosslinked nano beads or particle in the size range 5 nm to 10 μm, comprising PAMAM dendrimer with asymmetrical peripheral end groups such that one of the terminal groups is involved in formation of hydrogel and the other in involved in the conjugation of drugs or imaging agents and their methods of preparation. The said gel is formed by reaction of the PAMAM dendrimer with asymmetrical end groups with other polymer wherein the other polymer is selected from the group of linear, branched, hyperbranched or star shaped polymers with functionalized terminal groups. The PAMAM dendrimer with asymmetrical terminal groups consists of a Generation 2 and above PAMAM dendrimer with symmetrical end groups modified using the amino acids or their modified forms. The gel disclosed in the present invention is formed as small crosslinked particles in the size range 25 nm to 10 μm and is suitable for injectable delivery of hydrogel to any of the body orifices, tissues by intramuscular or subcutaneous route and ocular delivery for the purpose of therapeutic treatment and imaging. |
FILED | Thursday, March 31, 2011 |
APPL NO | 13/636715 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48207 (20130101) Original (OR) Class A61K 47/48784 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/028 (20130101) Compositions of Macromolecular Compounds C08L 79/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526800 | Hynes et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Richard O. Hynes (Winchester, Massachusetts); Alexandra Naba (Cambridge, Massachusetts); Karl Clauser (Boston, Massachusetts); Steven A. Carr (Boxford, Massachusetts); Kenneth Tanabe (Brookline, Massachusetts) |
ABSTRACT | Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with various aspects of cancer. Panels or signature sets of proteins useful in the detection, diagnosis and treatment of cancers as well as monitoring therapeutic progress in a cancer patient are provided herein along with methods for their detection and for their use in targeting imaging and/or therapeutic agents to the tumors via binding to the specified proteins. The proteins were identified using proteomics analyzes of tissue samples taken from cancer patients. In certain aspects the proteins are particularly useful in colon cancer patients. |
FILED | Thursday, March 14, 2013 |
APPL NO | 14/389080 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) A61K 31/192 (20130101) A61K 31/197 (20130101) A61K 31/215 (20130101) A61K 31/727 (20130101) A61K 38/486 (20130101) A61K 38/488 (20130101) A61K 38/4833 (20130101) A61K 47/48569 (20130101) Original (OR) Class A61K 47/48584 (20130101) A61K 47/48615 (20130101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2320/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57419 (20130101) G01N 33/57484 (20130101) G01N 33/57488 (20130101) G01N 33/57492 (20130101) G01N 2333/705 (20130101) G01N 2800/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526802 | Thompson et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | David H. Thompson (West Lafayette, Indiana); Aditya Kulkarni (West Lafayette, Indiana); Wei Deng (Shanghai, China PRC) |
ABSTRACT | The invention relates to nucleic acid complexes, methods of preparation thereof, and uses thereof for delivering a nucleic acid into a cell. |
FILED | Monday, November 17, 2014 |
APPL NO | 14/543386 |
ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 47/48969 (20130101) Original (OR) Class A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/87 (20130101) C12N 2710/10043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526888 | Horsager et al. |
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FUNDED BY |
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APPLICANT(S) | Second Sight Medical Products, Inc. (San Fernando, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Alan M Horsager (Los Angeles, California); Matthew J McMahon (Washington, District of Columbia); Robert J Greenberg (Los Angeles, California) |
ABSTRACT | In a visual prosthesis or other neural stimulator it is advantageous to provide non-overlapping pulses in order to provide independent control of brightness from different electrodes. Non-overlapping pulses on geographically close electrodes avoid electric-field interaction which leads to brightness summation or changes in the shape and area of percepts. It is advantageous to apply pulses to nearby electrodes in a way that the currents do not overlap in time at all. ‘Nearby’ is defined as within a few millimeters of each other. The same parameters that provide independent control of brightness also produce spatial patterns that the subjects' report as being similar to the sum of individual electrode phosphenes. Simultaneous stimulation of multiple electrodes can sometimes produce physical sensation or discomfort in the eye. Time-shifting the pulses cab also be used to reduce the physical sensations felt by the patient. |
FILED | Wednesday, December 18, 2013 |
APPL NO | 14/133274 |
ART UNIT | 3766 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) Original (OR) Class A61N 1/36046 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526894 | Greenberg et al. |
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FUNDED BY |
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APPLICANT(S) | Second Sight Medical Products, Inc. (San Fernando, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Robert Greenberg (Los Angeles, California); Avraham Caspi (Rehovot, Israel); Jessy Dorn (Los Angeles, California); Matthew J McMahon (Washington, District of Columbia) |
ABSTRACT | A visual prosthesis and a method of operating a visual prosthesis are disclosed. Neural stimulation through electrodes is controlled by spatial maps, where a grouped or random association is established between the data points of the acquired data and the electrodes. In this way distortions from the foveal pit and wiring mistakes in the implant can be corrected. Moreover, broken electrodes can be bypassed and a resolution limit can be tested, together with testing the benefit the patient receives from correct spatial mapping. |
FILED | Monday, July 06, 2015 |
APPL NO | 14/792497 |
ART UNIT | 3766 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/3605 (20130101) A61N 1/36046 (20130101) Original (OR) Class A61N 1/37235 (20130101) A61N 1/37247 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4661 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526895 | McClure et al. |
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FUNDED BY |
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APPLICANT(S) | Second Sight Medical Products, Inc. (San Fernando, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Kelly H McClure (Simi Valley, California); Richard A Castro (Santa Monica, California); Arup Roy (Valencia, California); Scott Loftin (Rosamond, California); Rongqing Dai (Valencia, California); Robert J Greenberg (Los Angeles, California); Sumit Yadav (Los Angeles, California) |
ABSTRACT | A visual prosthesis configured to convert a video image to stimulation patterns for stimulating visual neural tissue including a camera configured to obtain a video image, a video processing unit configured to receive the image from the camera and create stimulation patterns based upon the image, an implantable stimulation system suitable to stimulate visual neural tissue according to the stimulation patterns, a wireless communication system configured to send a stimulation signal from the video processing unit to the implantable stimulation system, and a voltage and current monitoring circuit in the video processing unit monitoring the stimulation signal sent by the video processing unit. |
FILED | Monday, July 13, 2015 |
APPL NO | 14/798274 |
ART UNIT | 3766 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/08 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36046 (20130101) Original (OR) Class A61N 1/37252 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526904 | Sahin et al. |
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FUNDED BY |
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APPLICANT(S) | Mesut Sahin (Clifton, New Jersey); Selim Unlu (Boston, Massachusetts); David S Freedman (Boston, Massachusetts); Ammar R Abdo (Belleville, New Jersey) |
ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
INVENTOR(S) | Mesut Sahin (Clifton, New Jersey); Selim Unlu (Boston, Massachusetts); David S Freedman (Boston, Massachusetts); Ammar R Abdo (Belleville, New Jersey) |
ABSTRACT | Stimulation of the central nervous system can be useful for treating neurological disorders. Wireless neurostimulating devices have the benefit that they can float in tissue and do not experience the sheering caused by tethering tension that connecting wires impose on the stimulators. An optically powered, logic controlled, CMOS microdevice that can decode telemetry data from an optical packet is a way of implementing wireless, addressable, microstimulators. Through the use of an optical packet, different devices can be addressed for stimulation, allowing spatially selective activation of neural tissue. The present invention, involves such a neural stimulation device, specifically an optically powered CMOS circuit that decodes telemetry data and determines whether it has been addressed. |
FILED | Friday, April 26, 2013 |
APPL NO | 13/871654 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/378 (20130101) Original (OR) Class A61N 1/3606 (20130101) A61N 1/3756 (20130101) A61N 1/3787 (20130101) A61N 1/36067 (20130101) A61N 1/36075 (20130101) A61N 1/37205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526915 | Kovach |
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FUNDED BY |
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APPLICANT(S) | John S. Kovach (East Setauket, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | John S. Kovach (East Setauket, New York) |
ABSTRACT | Disclosed herein are methods of inhibiting proliferation of a cancer cell or inducing apoptosis of a cancer cell, which does not overexpress N—CoR. Also disclosed herein are methods of inhibiting proliferation or inducing apoptosis of a cancer cell that overexpresses TCTP and methods for determining whether a compound is effective in inducing cell death. |
FILED | Thursday, April 25, 2013 |
APPL NO | 13/870763 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/337 (20130101) A61K 31/496 (20130101) A61K 38/20 (20130101) A61K 38/50 (20130101) A61K 38/212 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Original (OR) Class Heterocyclic Compounds C07D 493/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526922 | Hossack et al. |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | John A. Hossack (Charlottesville, Virginia); Brian R. Wamhoff (Charlottesville, Virginia); Alexander L. Klibanov (Charlottesville, Virginia) |
ABSTRACT | A method and related system for providing therapy to a treatment site, such as stenosis or other vasculature disease, at one or more locations of a subject, such as the vasculature. The method includes: advancing an ultrasound catheter to or in proximity to the subject's treatment site; infusing microbubbles into or proximal to the treatment site; and delivering ultrasonic energy from the ultrasound catheter. The ultrasonic energy may be adapted for: imaging the treatment site, translating the microbubbles into or in the vicinity of the treatment site and/or rupturing the microbubbles. |
FILED | Friday, October 25, 2013 |
APPL NO | 14/063830 |
ART UNIT | 3768 — Organic Chemistry |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/12 (20130101) A61B 8/445 (20130101) A61B 8/481 (20130101) A61B 17/2202 (20130101) A61B 2017/22088 (20130101) A61B 2017/22089 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) A61K 49/223 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0092 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527793 | Anderson, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | Rush University Medical Center (Chicago, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); RUSH UNIVERSITY MEDICAL CENTER (Chicago, Illinois) |
INVENTOR(S) | Robert A. Anderson, Jr. (Chicago, Illinois); Xiao-Hui Diao (Chicago, Illinois); Lourens J. D. Zaneveld (Sao Paulo, Brazil); Calvin J. Chany, II (Dubuque, Iowa); Aleksej Krunic (Chicago, Illinois); Donald P. Waller (Oak Brook, Illinois); Duane L. Venton (Lombard, Illinois); Sanjay Jain (Pune, India) |
ABSTRACT | Disclosed herein are compounds and compositions useful for reducing the risk of infection. In particular, disclosed herein are mandelic acid condensation polymers, compositions comprising such compounds, processes for producing such compounds, and methods of using such compounds. |
FILED | Friday, November 30, 2012 |
APPL NO | 14/361993 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/347 (20130101) C07C 59/48 (20130101) C07C 59/50 (20130101) Original (OR) Class C07C 67/465 (20130101) C07C 69/616 (20130101) C07C 2101/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527812 | Scheidt et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Karl A. Scheidt (Evanston, Illinois); Michael Todd Hovey, Jr. (Evanston, Illinois); Christopher Check (Evanston, Illinois) |
ABSTRACT | Transition metal-free catalytic methods for access to 2-arylindole compounds. |
FILED | Friday, May 01, 2015 |
APPL NO | 14/701814 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 209/08 (20130101) Original (OR) Class C07D 209/10 (20130101) C07D 209/12 (20130101) C07D 209/14 (20130101) C07D 209/26 (20130101) C07D 401/04 (20130101) C07D 409/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527819 | Watterson et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); UNIVERSITE DE STRASBOURG (Strasbourg, France); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Paris, France) |
ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, None); UNIVERSITE DE STRASBOURG (Strasbourg, France); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Paris, France) |
INVENTOR(S) | D. Martin Watterson (Chicago, Illinois); Linda Van Eldik (Chicago, Illinois); Jacques Haiech (Strasbourg, France); Marcel Hibert (Eschau, France); Jean-Jacques Bourguignon (Illkirch, France); Anastasia Velentza (San Diego, California); Wenhui Hu (Guangzhou, China PRC); Magdalena Zasadzki (Chicago, Illinois) |
ABSTRACT | The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications. |
FILED | Wednesday, December 03, 2014 |
APPL NO | 14/559421 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/502 (20130101) Heterocyclic Compounds C07D 237/20 (20130101) Original (OR) Class C07D 237/24 (20130101) C07D 237/34 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 413/12 (20130101) C07D 413/14 (20130101) C07D 487/04 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527823 | Carroll et al. |
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FUNDED BY |
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APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina); Dignity Health (Phoenix, Arizona); Virginia Commonwealth University (Richmond, Virginia) |
ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina); Dignity Health (Phoenix, Arizona); Virginia Commonwealth University (Richmond, Virginia) |
INVENTOR(S) | Frank Ivy Carroll (Durham, North Carolina); Bruce E. Blough (Raleigh, North Carolina); Hernan A. Navarro (Chapel Hill, North Carolina); S. Wayne Mascarella (Hillsborough, North Carolina); Ana Zamfira Muresan (Raleigh, North Carolina); M. Imad Damaj (Richmond, Virginia); Ronald J. Lukas (Phoenix, Arizona) |
ABSTRACT | The invention provides hydroxybupropion analogs capable of inhibiting the reuptake of one or more monoamines and/or acting as antagonists at nicotinic acetylcholine receptors. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine, and serotonin and/or may selectively bind to one or more nicotinic acetylcholine receptor subtypes. Such compounds may be used to treat conditions that are responsive to modification of monoamine levels and/or antagonism of nicotinic acetylcholine receptors, including drug dependency, depression, and obesity. |
FILED | Monday, November 10, 2014 |
APPL NO | 14/537124 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5375 (20130101) Heterocyclic Compounds C07D 265/32 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527834 | Lindsley et al. |
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FUNDED BY |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Nashville, Tennessee); Shaun R. Stauffer (Brentwood, Tennessee); Joseph David Panarese (Nashville, Tennessee) |
ABSTRACT | The invention relates to substituted 1-benzylquinoxalin-2(1H)-one analogs, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M1 (mAChR M1); methods for making the compounds; pharmaceutical compositions; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction. Exemplary 1-benzylquinoxalin-2(1H)-one compounds include compounds of the following formula: |
FILED | Monday, April 28, 2014 |
APPL NO | 14/787717 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 9/2018 (20130101) A61K 47/36 (20130101) Heterocyclic Compounds C07D 403/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527857 | Strum et al. |
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FUNDED BY |
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APPLICANT(S) | G1 Therapeutics, Inc. (Chapel Hill, North Carolina) |
ASSIGNEE(S) | GI Therapeutics, Inc. (Research Triangle Park, North Carolina) |
INVENTOR(S) | Jay Copeland Strum (Hillsborough, North Carolina); John Emerson Bisi (Apex, North Carolina); Patrick Joseph Roberts (Durham, North Carolina); Francis Xavier Tavares (Durham, North Carolina) |
ABSTRACT | This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders while minimizing the deleterious effects on healthy cells, for example healthy Hematopoietic Stem Cells and Progenitor Cells (HSPCs), associated with current treatment modalities. In one aspect, improved treatment of select RB-positive cancers is disclosed using specific compounds disclosed herein. In certain embodiments, the compounds described herein act as highly selective and, in certain embodiments, short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/214048 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/527 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 487/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527868 | Overman et al. |
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FUNDED BY |
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APPLICANT(S) | City of Hope (Duarte, California); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | CITY OF HOPE (Duarte, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Larry Eugene Overman (Corona Del Mar, California); Marcus Baumann (Durham, United Kingdom); Sangkil Nam (Tujunga, California); David Horne (Altadena, California); Richard Jove (Pasadena, California); Jun Xie (Duarte, California); Claudia Kowolik (Redondo Beach, California) |
ABSTRACT | Provided herein, inter alia, is the synthesis of ETP derivatives. The uses of the ETP derivatives described herein include treatment of cancer. |
FILED | Friday, April 17, 2015 |
APPL NO | 14/689682 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/548 (20130101) A61K 31/548 (20130101) A61K 31/706 (20130101) A61K 31/706 (20130101) A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) C07D 513/18 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527878 | Lawrence et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); EASTERN MICHIGAN UNIVERSITY (Ypsilanti, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); EASTERN MICHIGAN UNIVERSITY (Ypsilanti, Michigan) |
INVENTOR(S) | Daniel A. Lawrence (Ann Arbor, Michigan); Cory Emal (Ann Arbor, Michigan); Jacqueline Cale (Minneapolis, Minnesota); Enming Joe Su (Ann Arbor, Michigan); Mark Warnock (Brighton, Michigan); Shih-Hon Li (Ypsilanti, Michigan); Jeanne Ann Cupp (Fenton, Michigan) |
ABSTRACT | The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels. |
FILED | Tuesday, August 04, 2015 |
APPL NO | 14/817690 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/27 (20130101) A61K 31/50 (20130101) A61K 31/166 (20130101) A61K 31/235 (20130101) A61K 31/444 (20130101) A61K 31/495 (20130101) A61K 31/5375 (20130101) A61K 31/7034 (20130101) A61K 38/482 (20130101) A61K 38/1741 (20130101) Acyclic or Carbocyclic Compounds C07C 69/88 (20130101) C07C 69/90 (20130101) C07C 69/94 (20130101) C07C 229/12 (20130101) C07C 229/34 (20130101) C07C 235/68 (20130101) C07C 271/22 (20130101) C07C 271/54 (20130101) C07C 311/29 (20130101) C07C 311/49 (20130101) C07C 2101/14 (20130101) Heterocyclic Compounds C07D 213/82 (20130101) C07D 295/26 (20130101) C07D 295/195 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 13/08 (20130101) C07H 15/203 (20130101) Original (OR) Class Enzymes C12Y 304/21073 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527884 | McKee et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
INVENTOR(S) | Patrick A. McKee (Oklahoma City, Oklahoma); Kenneth W. Jackson (Edmond, Oklahoma); Kyung N. Lee (Oklahoma City, Oklahoma); Victoria J. Christiansen (Oklahoma City, Oklahoma) |
ABSTRACT | The presently disclosed and claimed inventive concepts include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related to disorders of fibrin and α2-antiplasmin and abnormal cell proliferation. The presently disclosed and claimed inventive concepts also include substrates of APCE and FAP, which may be used, for example, in screening methods for identifying such inhibitors. The presently disclosed and claimed inventive concepts further include, but are not limited to, methods of treating or inhibiting atherosclerosis and thrombus disorders by altering the ratios of types of plasma α2-antiplasmin and to methods of treating conditions involving abnormal cell proliferation such as cancers. |
FILED | Thursday, January 08, 2015 |
APPL NO | 14/592178 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/02 (20130101) Original (OR) Class C07K 14/8121 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527889 | Nichols et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Ruthann Nichols (Ann Arbor, Michigan); Margaret Westfall (Ann Arbor, Michigan) |
ABSTRACT | Provided herein methods and compositions directed to RFRP-1 polypeptides for modulating cardiac contractile function, for preventing and/or treating cardiac disorders. |
FILED | Wednesday, December 24, 2014 |
APPL NO | 14/582553 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/07 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) Peptides C07K 5/08 (20130101) C07K 5/1016 (20130101) C07K 5/1024 (20130101) C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/5008 (20130101) G01N 33/5061 (20130101) G01N 33/9453 (20130101) G01N 2500/10 (20130101) G01N 2800/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527890 | Blumberg et al. |
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FUNDED BY |
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APPLICANT(S) | THE BRIGHAM AND WOMENS'S HOSPITAL, INC. (Boston, Massachusetts); BIOGEN IDEC MA INC. (Cambridge, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Richard S. Blumberg (Waltham, Massachusetts); Timo Rath (Cambridge, Massachusetts); Kristi Baker (Brookline, Massachusetts); Adam Mezo (Carmel, Indiana); Zachary Taylor (Crestview Hills, Kentucky); Kevin McDonnell (Lexington, Massachusetts); Rosa Maria Silva Garcia Grenha (Arlington, Massachusetts) |
ABSTRACT | The invention provided herein includes isolated polypeptides that specifically block the interaction between neonatal Fc receptor (FcRn) and albumin. Blocking the interaction treats diseases and conditions caused by increased amounts of albumin or modified albumin that possesses pathogenic properties wherein it is deemed desirable to decrease albumin levels. Accordingly, also provided are methods of using these isolated polypeptides to treat various diseases and conditions caused by increased amounts of albumin or modified albumin that possesses pathogenic properties. The invention provided herein also includes isolated polypeptides capable of binding to a non-IgG and non-albumin competitive site on an FcRn alpha 3 domain. These can be useful for tracking FcRn without inhibiting IgG or albumin binding or function. Accordingly, the invention also includes methods and systems to track FcRn without inhibiting IgG or albumin binding or function. |
FILED | Wednesday, June 18, 2014 |
APPL NO | 14/897999 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) C07K 14/001 (20130101) Original (OR) Class C07K 14/765 (20130101) C07K 14/70535 (20130101) C07K 2319/00 (20130101) C07K 2319/31 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527895 | Hickey et al. |
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FUNDED BY |
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APPLICANT(S) | Robert J. Hickey (Indianapolis, Indiana); Linda H. Malkas (Indianapolis, Indiana) |
ASSIGNEE(S) | |
INVENTOR(S) | Robert J. Hickey (Indianapolis, Indiana); Linda H. Malkas (Indianapolis, Indiana) |
ABSTRACT | Administration of compositions comprising cell-permeable cancer-specific proliferating cell nuclear antigen derived peptides and their variants reduces the proliferation of cancer cells and also augments cytotoxic effects of chemotherapeutics. The compositions are effective in cells harboring mutations in DNA repair proteins. |
FILED | Thursday, October 03, 2013 |
APPL NO | 14/045223 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) A61K 38/08 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/10 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/4738 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527903 | Dimitrov |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represent by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Dimiter S. Dimitrov (Frederick, Maryland) |
ABSTRACT | Described herein are engineered antibody constant domain molecules, such as CH2 or CH3 domain molecules, comprising at least one mutation, or comprising at least one complementarity determining region (CDR), or a functional fragment thereof, engrafted in a loop region of the CH2 domain. The CH2 domain molecules described herein are small, stable, soluble, exhibit little to no toxicity and are capable of binding antigen. |
FILED | Tuesday, October 01, 2013 |
APPL NO | 14/043366 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/005 (20130101) C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/94 (20130101) C07K 2317/524 (20130101) C07K 2317/565 (20130101) C07K 2318/10 (20130101) C07K 2318/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527904 | Balazs et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Alejandro Benjamin Balazs (Berkeley, California); David Baltimore (Pasadena, California) |
ABSTRACT | Disclosed herein are compositions, systems and methods for delivery of proteins of interest using adeno-associated virus (AAV) vectors. |
FILED | Friday, September 12, 2014 |
APPL NO | 14/484842 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 16/109 (20130101) Original (OR) Class C07K 16/1045 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14141 (20130101) C12N 2750/14143 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527917 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Yong-Jun Liu (Pearland, Texas); Kui Shin Voo (Pearland, Texas); Laura Bover (Pearland, Texas); Naoya Tsurushita (Palo Alto, California); J. Yun Tso (Menlo Park, California); Shankar Kumar (Pleasanton, California) |
ABSTRACT | Human antibodies, preferably recombinant human antibodies, both humanized and chimeric, which specifically bind to human OX40 are disclosed. Preferred antibodies have high affinity for OX40 receptor and activate the receptor in vitro and in vivo. The antibody can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, are useful for modulating receptor activity, e.g., in a human subject suffering from a disorder in which OX40 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies are provided, and methods of synthesizing the recombinant human antibodies, are also provided. |
FILED | Tuesday, September 15, 2015 |
APPL NO | 14/854908 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2878 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/74 (20130101) C07K 2317/75 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527919 | Wu et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Anna M. Wu (Sherman Oaks, California); Robert E. Reiter (Los Angeles, California); Eric J. Lepin (Los Angeles, California); James D. Marks (Kensington, California); Yu Zhou (San Francisco, California) |
ABSTRACT | The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis, prognosis, treatment, visualization, and the like. The Present invention also provides methods for the detection, visualization, and treatment of various cancers expressing PSCA. |
FILED | Friday, December 05, 2014 |
APPL NO | 14/562269 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 51/1096 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/3069 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2317/626 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/57434 (20130101) G01N 33/57492 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527924 | Marasco et al. |
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FUNDED BY |
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APPLICANT(S) | Wayne A. Marasco (Wellesley, Massachusetts); Jianhua Sui (Stoneham, Massachusetts); Yuval Avnir (Boston, Massachusetts) |
ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts); Jianhua Sui (Stoneham, Massachusetts); Yuval Avnir (Boston, Massachusetts) |
ABSTRACT | Disclosed is a humanized monoclonal antibody that binds to the human immunoglobulin heavy chain variable region germline gene VHI-69. The antibody is derived from Mab G6 and recognizes the same epitope. Moreover, the antibody is used in combination with vaccines to augment an immune response to the antigen. |
FILED | Thursday, June 02, 2011 |
APPL NO | 13/700974 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/145 (20130101) A61K 39/39566 (20130101) A61K 2039/55516 (20130101) Peptides C07K 16/1018 (20130101) C07K 16/4216 (20130101) C07K 16/4241 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/567 (20130101) C07K 2317/622 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528091 | Lin et al. |
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FUNDED BY |
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APPLICANT(S) | Joseph H. Lin (Menlo Park, California); Judith A. Shizuru (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Joseph H. Lin (Menlo Park, California); Judith A. Shizuru (Palo Alto, California) |
ABSTRACT | Substantially enriched mammalian lung endothelial and epithelial progenitor cell populations are provided. Methods are provided for the isolation and in vivo differentiation of such lung progenitor cells. The progenitor cells are obtained from lung tissue, including fetal and adult tissues. The cells are useful in transplantation, for experimental evaluation, and as a source of lineage and cell specific products, including mRNA species useful in identifying genes specifically expressed in these cells, and as targets for the discovery of factors or molecules that can affect them. |
FILED | Monday, June 18, 2007 |
APPL NO | 12/308351 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0689 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528124 | Fahrenkrug et al. |
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FUNDED BY |
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APPLICANT(S) | Recombinetics, Inc. (Saint Paul, Minnesota) |
ASSIGNEE(S) | Recombinetics, Inc. (Saint Paul, Minnesota) |
INVENTOR(S) | Scott C. Fahrenkrug (Minneapolis, Minnesota); Daniel F. Carlson (Woodbury, Minnesota) |
ABSTRACT | Methods, uses, and animals for introgression of alleles between animals, including SNPs. One embodiment involves introducing a targeted targeting endonuclease system and a HDR template into a cell with a mismatch in the binding of the targeting endonuclease and the targeted site. |
FILED | Monday, April 28, 2014 |
APPL NO | 14/263446 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Peptides C07K 14/47 (20130101) C07K 14/715 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 15/8509 (20130101) C12N 15/8771 (20130101) C12N 15/8778 (20130101) C12N 2750/14143 (20130101) C12N 2800/30 (20130101) C12N 2800/90 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528151 | Ju et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Dae Hyun Kim (New York, New York); Lanrong Bi (New York, New York); Qinglin Meng (Foster City, California); Xiaoxu Li (New York, New York) |
ABSTRACT | This invention provides a process for sequencing single-stranded DNA employing modified nucleotides. |
FILED | Tuesday, April 01, 2014 |
APPL NO | 14/242487 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6823 (20130101) C12Q 1/6823 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2523/107 (20130101) C12Q 2523/107 (20130101) C12Q 2523/319 (20130101) C12Q 2523/319 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528154 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | Jeannie T. Lee (Weston, Massachusetts); Li-Feng Zhang (Jalan Bahar, Singapore) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Jeannie T. Lee (Weston, Massachusetts); Li-Feng Zhang (Jalan Bahar, Singapore) |
ABSTRACT | Disclosed herein are methods and compositions for the identification of teloRNA marks to assess the differentiation status of an individual stem cell or a population of stem cells, to diagnose whether and to what extent a stem cell or stem cell culture has already initiated cell differentiation, and to monitor the differentiation status of an individual stem cell or a stem cell culture during passage. The use of these methods and compositions to monitor the pluripotency and differentiation status of a stem cell or stem cell culture during differentiation enables the identification of undifferentiated and pluripotent stem cells prior to the initiation of differentiation. The methods and compositions can also be used to assess and maintain cell viability; to identify cells or a population of cells that are in a state of poor cell health; and to reduce cell growth or treat a diseased cell including, for example, pre-cancerous cells, cancerous cells, apoptotic cells, aging cells, cells undergoing stress, and otherwise diseased or dysfunctional cells. |
FILED | Monday, January 12, 2009 |
APPL NO | 12/812489 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528161 | Willey et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
INVENTOR(S) | James C. Willey (Toledo, Ohio); Jiyoun Yeo (Maumee, Ohio); Erin Crawford (Rossford, Ohio) |
ABSTRACT | Described herein are materials, methods, and kits enabling accurate and reproducible two-color reverse-transcription real-time quantitative PCR (RT-qPCR) for quality-controlled molecular diagnostic testing of samples that may contain degraded RNA. In certain aspects described herein are materials, methods, and kits for use in the molecular diagnostic testing of lung cancer in FFPE samples and/or fresh-frozen samples. Also described herein are materials and methods to control for inter-experimental variation occurring during two-color RT-qPCR amplification arising from variation in fluorescence specific activity, use of different thermocyclers, and inter-laboratory differences. |
FILED | Wednesday, February 11, 2015 |
APPL NO | 14/619285 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) C12Q 2600/166 (20130101) Electric Digital Data Processing G06F 19/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528966 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Lihong Wang (Creve Coeur, Missouri); Konstantin Maslov (Affton, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Lihong Wang (Creve Coeur, Missouri); Konstantin Maslov (Affton, Missouri) |
ABSTRACT | Noninvasively imaging biological tissue using a handheld device. A light pulse is focused into a predetermined area inside an object using a flexibly mounted cantilever beam, acoustic waves emitted by the object in response to the at least one light pulse are detected by a transducer, and an image of the predetermined area inside the object is generated based on a signal generated by the transducer representative of the acoustic waves. |
FILED | Wednesday, October 21, 2009 |
APPL NO | 13/125522 |
ART UNIT | 3777 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) A61B 5/0095 (20130101) A61B 5/415 (20130101) A61B 5/418 (20130101) A61B 5/4866 (20130101) A61B 5/14552 (20130101) A61B 8/00 (20130101) A61B 8/06 (20130101) A61B 8/4444 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/0672 (20130101) G01N 29/2418 (20130101) Original (OR) Class G01N 2291/0427 (20130101) G01N 2291/02475 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528982 | Lancaster et al. |
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FUNDED BY |
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APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
INVENTOR(S) | Johnathan Lancaster (Tampa, Florida); Douglas Marchion (Seminole, Florida); Dung-Tsa Chen (Tampa, Florida) |
ABSTRACT | Despite initial sensitivity BAD-protein phosphorylation were evaluated in patient samples and cell lines as determinants of chemo-sensitivity and/or clinical outcome, and as therapeutic targets. Induced in-vitro OVCA cisplatin-resistance was associated with BAD-pathway expression. Expression of the pathway was also associated with resistance of 7 different cancers cell-types to 8 chemotherapeutic agents. Phosphorylation of the BAD-protein was associated with platinum-resistance in OVCA cells and primary OVCA specimens, and also overall patient survival. Targeted modulation of BAD-phosphorylation levels influenced cisplatin-sensitivity. A 47-gene BAD-pathway signature was associated in-vitro phospho-BAD levels and with survival of 838 patients with ovarian, breast, colon, and brain cancer. The survival advantage associated with both BAD-phosphorylation and also the BAD-pathway signature was independent of surgical cytoreductive status. The BAD apoptosis pathway influences human cancer chemo-sensitivity and overall survival. The pathway is useful as a biomarker of therapeutic response, patient survival, and therapeutic target. |
FILED | Monday, August 26, 2013 |
APPL NO | 14/010003 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) Original (OR) Class G01N 33/57449 (20130101) G01N 2440/14 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528993 | Zhou et al. |
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FUNDED BY |
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APPLICANT(S) | The UAB Research Foundation (Birmingham, Alabama) |
ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
INVENTOR(S) | Tong Zhou (Birmingham, Alabama); Robert P. Kimberly (Birmingham, Alabama) |
ABSTRACT | Provided herein is a method of reversing or preventing a target cell's resistance to a death receptor agonist. Also provided are methods of screening for biomarkers resistance of and monitoring resistance to death receptor agonists. Also provided are methods of selectively inducing apoptosis in a target cell, treating a subject with cancer, autoimmune or inflammatory diseases, comprising administering compositions provided herein. Further provided are compositions comprising agents that modulate CARD containing proteins. |
FILED | Friday, May 31, 2013 |
APPL NO | 13/907035 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/40 (20130101) C07K 16/2878 (20130101) C07K 2317/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/6863 (20130101) G01N 33/57492 (20130101) Original (OR) Class G01N 2333/914 (20130101) G01N 2333/7151 (20130101) G01N 2333/70578 (20130101) G01N 2500/02 (20130101) G01N 2800/44 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528995 | Osterfeld et al. |
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FUNDED BY |
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APPLICANT(S) | MagArray, Inc. (Milpitas, California) |
ASSIGNEE(S) | MagArray, Inc. (Milpitas, California) |
INVENTOR(S) | Sebastian J. Osterfeld (Mountain View, California); Shan Xiang Wang (Palo Alto, California) |
ABSTRACT | Provided are high-throughput detection systems. The systems include a magnetic sensor device, a magnetic field source and a reservoir plate that includes a plurality of fluid reservoirs. The magnetic sensor device includes a support with two or more elongated regions each having a magnetic sensor array disposed at a distal end. Also provided are methods in which the subject high-throughput detection systems find use. |
FILED | Friday, September 04, 2015 |
APPL NO | 14/846499 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00317 (20130101) B01J 2219/00655 (20130101) B01J 2219/00662 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 9/523 (20130101) B01L 2300/0829 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 15/00 (20130101) B82Y 30/00 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) G01N 27/3276 (20130101) G01N 33/585 (20130101) Original (OR) Class G01N 33/587 (20130101) G01N 35/026 (20130101) G01N 35/0098 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0094 (20130101) G01R 33/1269 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/92 (20130101) Y10S 977/773 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529001 | Van de Water et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Judy Van de Water (Capay, California); Daniel Braunschweig (Davis, California) |
ABSTRACT | The present invention provides diagnostic methods for determining the risk of developing an autism spectrum disorder (ASD) in a fetus or child by detecting in a biological sample from the mother antibodies that bind to one or more biomarkers selected from the group consisting of lactate dehydrogenase (LDH), guanine deaminase (GDA), collapsin response mediator protein 1 (CRMP1), stress-induced phosphoprotein 1 (STIP1), alpha subunit of the barbed-end actin binding protein Cap Z (CAPZA2), Y Box Binding Protein 1 (YBX1), eukaryotic translation and elongation factor 1A1 (EEF1A1), microtubule-associated protein Tau (MAPT), dihydropyrimidinase-like protein 2 (DPYSL2), dynamin 1-like protein (DNM1L), radixin (RDX), moesin (MSN), and ezrin (EZR). The invention further provides methods of preventing or reducing the risk of a fetus or child developing an ASD by administering to the mother an agent that blocks the binding of maternal antibodies to the one or more fetal biomarkers listed above or by removing from the mother antibodies that bind to the one or more fetal biomarkers. |
FILED | Wednesday, January 30, 2013 |
APPL NO | 13/754846 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 2800/28 (20130101) G01N 2800/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529003 | Kleinfeld et al. |
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FUNDED BY |
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APPLICANT(S) | Alan Marc Kleinfeld (La Jolla, California); Andrew Henry Huber (Encinitas, California); James Patrick Kampf (San Diego, California); Thomas Kwan (San Diego, California); Baolong Zhu (San Diego, California) |
ASSIGNEE(S) | Alan Marc Kleinfeld (La Jolla, California) |
INVENTOR(S) | Alan Marc Kleinfeld (La Jolla, California); Andrew Henry Huber (Encinitas, California); James Patrick Kampf (San Diego, California); Thomas Kwan (San Diego, California); Baolong Zhu (San Diego, California) |
ABSTRACT | Identification and use of proteins fluorescently labeled and that undergo a change in fluorescence index upon binding bilirubin are described. Probes are disclosed which are labeled at a cysteine or lysine residue and also probes labeled at both cysteine and lysine with two different fluorophores. These probes are useful for determination of unbound bilirubin levels in a fluid sample. |
FILED | Friday, August 24, 2012 |
APPL NO | 14/238144 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/47 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/92 (20130101) G01N 33/533 (20130101) G01N 33/582 (20130101) G01N 33/728 (20130101) Original (OR) Class G01N 2800/52 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/146666 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529005 | Orth et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Kim Orth (Dallas, Texas); Hyeilin Ham (Dallas, Texas); Anne-Marie Krachler (Malvern, United Kingdom) |
ABSTRACT | The present invention relates to methods and compositions for preventing or inhibiting pathogenic bacterial infections in a subject caused by pathogenic bacteria expressing a MAM polypeptide by administering to a subject a composition comprising a MAM polypeptide or a non-pathogenic bacterium expressing a MAM polypeptide, or a combination thereof. |
FILED | Tuesday, September 22, 2015 |
APPL NO | 14/861709 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/135 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 38/164 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 33/554 (20130101) G01N 33/56911 (20130101) G01N 2333/195 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529126 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Hongrui Jiang (Madison, Wisconsin); Yen-Sheng Lu (Madison, Wisconsin); Hewei Liu (Madison, Wisconsin) |
ABSTRACT | A Fresnel zone plate is provided for encountering incident light having a wavelength. The Fresnel zone plate has a focal length and a wafer including alternating transparent and opaque zones, and a mourning surface. A plurality of silicon nanowires extend into opaque zone of the wafer. A mechanically stretchable tuning structure is mounted to the mounting surface such that stretching of the tuning structure varies the focal length of the Fresnel zone plate. |
FILED | Thursday, January 09, 2014 |
APPL NO | 14/151087 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1828 (20130101) Original (OR) Class G02B 5/1876 (20130101) G02B 27/42 (20130101) G02B 2005/1804 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529974 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Peter C. Li (McLean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Alexandria, Virginia); James M. Wilson (Cedaredge, Colorado); Jae I. Yoon (Centreville, Virginia); Manabu Torii (Newark, Delaware); Carla S. Thomas (Bodega Bay, California) |
ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
INVENTOR(S) | Peter C. Li (McLean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Alexandria, Virginia); Mark G. Polyak (Alexandria, Virginia); James M. Wilson (Cedaredge, Colorado); Jae I. Yoon (Centreville, Virginia); Manabu Torii (Newark, Delaware); Carla S. Thomas (Bodega Bay, California) |
ABSTRACT | A system and method involves detecting operational social disruptive events on a global scale, assigning event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling propagation of events for containment and forecasting purposes. |
FILED | Wednesday, July 27, 2011 |
APPL NO | 13/192160 |
ART UNIT | 2451 — Computer Networks |
CURRENT CPC | Electric Digital Data Processing G06F 17/30616 (20130101) G06F 19/3493 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 50/22 (20130101) G06Q 50/26 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/08072 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09532029 | Pallone et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
INVENTOR(S) | Matthew Pallone (White River Junction, Vermont); Paul M. Meaney (Hanover, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire) |
ABSTRACT | Systems and methods generate a 3D model of a surface of an object immersed in a transparent liquid within a stationary cylindrical transparent tank. First and second laser line projectors and a camera are rotated around a central axis of the cylindrical tank. The first and second laser line projectors each generate a laser line perpendicular to a plane or rotation and aligned with the center of rotation. The camera images the object. An image from the camera is captured at each of several angular positions of the camera relative to a reference position of the stationary cylindrical tank. The captured images are processed to determine, for each laser line within each image, a plurality of 3D positions where the laser line is incident upon a surface of the object. In embodiments, images are corrected with ray tracing or image warping and registration functions. |
FILED | Saturday, December 22, 2012 |
APPL NO | 13/726050 |
ART UNIT | 2483 — Recording and Compression |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0091 (20130101) A61B 5/0507 (20130101) A61B 5/1077 (20130101) A61B 5/4312 (20130101) Image Data Processing or Generation, in General G06T 1/0007 (20130101) G06T 5/006 (20130101) G06T 7/0057 (20130101) G06T 15/06 (20130101) G06T 17/00 (20130101) G06T 2210/41 (20130101) Pictorial Communication, e.g Television H04N 13/0221 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09532451 | Greenberg et al. |
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FUNDED BY |
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APPLICANT(S) | SECOND SIGHT MEDICAL PRODUCTS, INC. (Sylmar, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Robert Greenberg (Los Angeles, California); Neil Talbot (La Crescenta, California); Jerry Ok (Canyon Country, California); Jordan Neysmith (Pasadena, California); David Zhou (Saugus, California) |
ABSTRACT | The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package, that is suitable for implantation in living tissue, such as for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a studbump connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue. |
FILED | Monday, January 04, 2016 |
APPL NO | 14/987574 |
ART UNIT | 3766 — Digital Audio Data Processing |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/3758 (20130101) A61N 1/36046 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) H05K 1/028 (20130101) H05K 1/113 (20130101) Original (OR) Class H05K 3/4038 (20130101) H05K 3/4084 (20130101) H05K 2203/0733 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 09526811 | Comer et al. |
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FUNDED BY |
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APPLICANT(S) | STRATATECH CORPORATION (Madison, Wisconsin) |
ASSIGNEE(S) | STRATATECH CORPORATION (Madison, Wisconsin) |
INVENTOR(S) | Allen R. Comer (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin); Barry Steiglitz (Madison, Wisconsin) |
ABSTRACT | The present invention relates generally to systems and methods for preparing, storing, shipping and using skin equivalents made by organotypic culture. In particular, the present invention relates to systems and methods for producing, transporting, storing and using skin equivalents produced by organotypic culture at reduced temperatures, preferably from 2-8 degrees Celsius to ambient temperature. The methods include sterile packaging of the grafts so that the sterility and integrity of the package is maintained until the time of use for grafting purposes. |
FILED | Thursday, March 26, 2015 |
APPL NO | 14/669095 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/105 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/60 (20130101) A61L 27/3691 (20130101) Original (OR) Class A61L 27/3813 (20130101) A61L 2430/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526885 | Khanna et al. |
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FUNDED BY |
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APPLICANT(S) | Puneet Khanna (Clifton Park, New York); Shekhar Bhansali (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Puneet Khanna (Clifton Park, New York); Shekhar Bhansali (Tampa, Florida) |
ABSTRACT | Microneedles with sharpened tips are fabricated without any reduction to the shaft diameter below the tip. By sharpening the tip and not the entire length of the microneedle, their mechanical strength is maintained. The microneedles are fabricated out of a wafer substrate using lithography and deep reactive-ion etching (DRIE). By controlling the timing of the DRIE as the photoresist depletes, the sharpness and angle of the tips are controlled. |
FILED | Monday, March 24, 2014 |
APPL NO | 14/223515 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0053 (20130101) Producing Decorative Effects; Mosaics; Tarsia Work; Paperhanging B44C 1/227 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526946 | Zets et al. |
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FUNDED BY |
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APPLICANT(S) | Gary Zets (Casselberry, Florida); Bruce Mortimer (Casselberry, Florida) |
ASSIGNEE(S) | |
INVENTOR(S) | Gary Zets (Casselberry, Florida); Bruce Mortimer (Casselberry, Florida) |
ABSTRACT | A system and method for providing therapy and assessment utilizing vibrotactile feedback is disclosed and claimed. Such treatment is useful for the treatment of disequilibrium and balance disorders. The system and method uses sensors such as force plates, inertial sensors, and three dimensional cameras to provide a subject with vibrotactile feedback in response to an attempt by the subject to perform predetermined motions. Predetermined motions are motions such as stand, sit-to-stand, reach, bend, functional gait, functional gait plus headshake, and other functional tasks. Vibrotactile stimulation may be applied during the subject's performance of a functional gait task as a disruptive input. Variance and rate of change of variance between measured and expected parameters are determined and used as a tool for assessment, and may also be used for providing real-time vibrotactile training. Such assessment and therapy is useful in the treatment of Traumatic Brain Injury (TBI). |
FILED | Friday, November 18, 2011 |
APPL NO | 13/300333 |
ART UNIT | 3764 — Organic Chemistry |
CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 24/00 (20130101) Original (OR) Class A63B 24/0003 (20130101) A63B 24/0006 (20130101) A63B 24/0021 (20130101) A63B 2024/0009 (20130101) A63B 2024/0012 (20130101) A63B 2024/0015 (20130101) A63B 2024/0025 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 21/00 (20130101) G09B 21/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527050 | Howell, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | Peter B Howell, Jr. (Gaithersburg, Maryland); Richard Eitel (Lexington, Kentucky); Joel P Golden (Fort Washington, Maryland); Frances S Ligler (Potomac, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
INVENTOR(S) | Peter B Howell, Jr. (Gaithersburg, Maryland); Richard Eitel (Lexington, Kentucky); Joel P Golden (Fort Washington, Maryland); Frances S Ligler (Potomac, Maryland) |
ABSTRACT | A magnetic bead trap-and-mixer includes a channel having openings at opposing ends, and a rotor adjacent to the channel and comprising a permanent magnet, wherein the rotor is adapted to apply a magnetic field to the channel of sufficient strength to direct the movement of magnetic beads therein. In aspects, the channel is straight and/or has narrowed end. In further aspects, the rotor generates in the channel areas of areas of strong magnetic fields alternating with areas of very weak magnetic fields and the strong magnetic fields extend entirely across the channel. |
FILED | Friday, January 28, 2011 |
APPL NO | 13/015731 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 7/00908 (20130101) B01F 13/0818 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527062 | Iezzi et al. |
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FUNDED BY |
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APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Brian C. Iezzi (Raleigh, North Carolina); Yanpeng Li (Raleigh, North Carolina); Linyou Cao (Raleigh, North Carolina); Yifei Yu (Raleigh, North Carolina) |
ABSTRACT | The present disclosure relates to nanosheet synthesis. More particularly, the present disclosure relates to molybdenum sulfide (MoS2) atomic thin films and hydrogen evolution reactions. In one or more embodiments, a synthesis process may include sublimation of sulfur and MoCl5, reaction of MoCl5 and S to produce gaseous MoS2 species, transfer of the MoS2 species by carrier gas, diffusion of MoS2 species from the gas phase onto receiving substrates, and precipitation of MoS2 on the substrates. |
FILED | Friday, May 09, 2014 |
APPL NO | 14/274154 |
ART UNIT | 1754 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/28 (20130101) B01J 27/051 (20130101) Original (OR) Class B01J 35/004 (20130101) B01J 37/0238 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09527413 — Reclining seat to mitigate the effects of mine blast load on spine and lower leg injuries
US 09527413 | Thyagarajan et al. |
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FUNDED BY |
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APPLICANT(S) | Ravi S. Thyagarajan (Novi, Michigan); Jaisankar Ramalingam (Farmington Hills, Michigan); Robert G. Kargus (Woodbine, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Ravi S. Thyagarajan (Novi, Michigan); Jaisankar Ramalingam (Farmington Hills, Michigan); Robert G. Kargus (Woodbine, Maryland) |
ABSTRACT | A seat assembly reclines during an under-vehicle explosion or other upward impact on the vehicle to mitigate spinal and lower leg damage to a human occupant. The seat assembly has a back frame portion and a lower frame portion. The lower frame portion has a pivotal connection with an energy absorbing mechanism mounted to the vehicle floor. The pivotal connection includes a stop mechanism to prevent seat assembly tilt during normal vehicle operation but allow tilt due to an explosion. A second mechanism is disposed between the back frame portion and the floor; this mechanism controls the seat assembly pivot and provides further absorbing of energy from the upward impact. Projections from the front of the lower frame portion toward the floor can be used to enhance seat assembly pivoting; specially designed seat engagement levers can be used for this purpose as well. |
FILED | Tuesday, November 12, 2013 |
APPL NO | 14/078059 |
ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Seats Specially Adapted for Vehicles; Vehicle Passenger Accommodation Not Otherwise Provided for B60N 2/4242 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527608 | Sotnikov et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Vladimir Sotnikov (Springboro, Ohio); Tony Kim (Xenia, Ohio) |
ABSTRACT | A method of reducing densities of harmful charged radiation belt particles is includes providing a space-based antenna having a first antenna portion and second antenna portion. The first antenna portion and the second antenna portion are oriented such that their loop planes are perpendicular with respect to the magnetic field of the Earth. The first antenna portion and the second antenna portion are energized with a first frequency and a second frequency, respectively, wherein the first frequency and the second frequency satisfy the relationship that the ratio of the first frequency to the second frequency is equal to the ratio of the second radius to the first radius. The trajectory of energetic particles in the radiation belt, such that the trajectories of energetic particles are shifted into a loss cone. |
FILED | Monday, November 30, 2015 |
APPL NO | 14/954031 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/54 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 7/00 (20130101) H01Q 21/29 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527722 | Rastegar |
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FUNDED BY |
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APPLICANT(S) | Jahangir S Rastegar (Stony Brook, New York) |
ASSIGNEE(S) | OMNITEK PARTNERS LLC (Ronkonkoma, New York) |
INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York) |
ABSTRACT | A MEMS sensor including: a base structure; at least one component formed from the base structure which moves relative to the base structure; and one or more locking mechanisms for locking the at least one component in a predetermined stationary position in response to external stimuli exceeding predetermined thresholds in at least first and second directions, where the first direction is different from the second direction. |
FILED | Tuesday, June 11, 2013 |
APPL NO | 13/915602 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0016 (20130101) Original (OR) Class Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0195 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5755 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) G01P 15/125 (20130101) G01P 15/0891 (20130101) G01P 2015/0814 (20130101) G01P 2015/0837 (20130101) G01P 2015/0871 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527741 | Kumar et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Priyank Vijaya Kumar (Cambridge, Massachusetts); Neelkanth M. Bardhan (Cambridge, Massachusetts); Angela Belcher (Lexington, Massachusetts); Jeffrey Grossman (Brookline, Massachusetts) |
ABSTRACT | Embodiments described herein generally relate to compositions comprising a graphene oxide species. In some embodiments, the compositions advantageously have relatively high oxygen content, even after annealing. |
FILED | Monday, May 05, 2014 |
APPL NO | 14/270276 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/043 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527806 | Whitten et al. |
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FUNDED BY |
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APPLICANT(S) | David G. Whitten (Albuquerque, New Mexico); Kirk S. Schanze (Gainesville, Florida); Anand Parthasarathy (Gainesville, Florida); Eunkyung Ji (Albuquerque, New Mexico); Motokatsu Ogawa (Sherman Oaks, California); Thomas S. Corbitt (Albuquerque, New Mexico); Dimitri Dascier (Albuquerque, New Mexico); Ying Wang (Albuquerque, New Mexico); Linnea K. Ista (Albuquerque, New Mexico); Eric H. Hill (Donostia, Spain) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico); University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | David G. Whitten (Albuquerque, New Mexico); Kirk S. Schanze (Gainesville, Florida); Anand Parthasarathy (Gainesville, Florida); Eunkyung Ji (Albuquerque, New Mexico); Motokatsu Ogawa (Sherman Oaks, California); Thomas S. Corbitt (Albuquerque, New Mexico); Dimitri Dascier (Albuquerque, New Mexico); Ying Wang (Albuquerque, New Mexico); Linnea K. Ista (Albuquerque, New Mexico); Eric H. Hill (Donostia, Spain) |
ABSTRACT | The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity. |
FILED | Wednesday, July 13, 2011 |
APPL NO | 13/809572 |
ART UNIT | 1672 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 217/14 (20130101) C07C 217/20 (20130101) C07C 309/11 (20130101) C07C 309/24 (20130101) Original (OR) Class Heterocyclic Compounds C07D 333/16 (20130101) C07D 487/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 75/00 (20130101) C08G 2261/312 (20130101) C08G 2261/3328 (20130101) C08G 2261/3422 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527884 | McKee et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
INVENTOR(S) | Patrick A. McKee (Oklahoma City, Oklahoma); Kenneth W. Jackson (Edmond, Oklahoma); Kyung N. Lee (Oklahoma City, Oklahoma); Victoria J. Christiansen (Oklahoma City, Oklahoma) |
ABSTRACT | The presently disclosed and claimed inventive concepts include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related to disorders of fibrin and α2-antiplasmin and abnormal cell proliferation. The presently disclosed and claimed inventive concepts also include substrates of APCE and FAP, which may be used, for example, in screening methods for identifying such inhibitors. The presently disclosed and claimed inventive concepts further include, but are not limited to, methods of treating or inhibiting atherosclerosis and thrombus disorders by altering the ratios of types of plasma α2-antiplasmin and to methods of treating conditions involving abnormal cell proliferation such as cancers. |
FILED | Thursday, January 08, 2015 |
APPL NO | 14/592178 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/02 (20130101) Original (OR) Class C07K 14/8121 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527895 | Hickey et al. |
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FUNDED BY |
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APPLICANT(S) | Robert J. Hickey (Indianapolis, Indiana); Linda H. Malkas (Indianapolis, Indiana) |
ASSIGNEE(S) | |
INVENTOR(S) | Robert J. Hickey (Indianapolis, Indiana); Linda H. Malkas (Indianapolis, Indiana) |
ABSTRACT | Administration of compositions comprising cell-permeable cancer-specific proliferating cell nuclear antigen derived peptides and their variants reduces the proliferation of cancer cells and also augments cytotoxic effects of chemotherapeutics. The compositions are effective in cells harboring mutations in DNA repair proteins. |
FILED | Thursday, October 03, 2013 |
APPL NO | 14/045223 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) A61K 38/08 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/10 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/4738 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528082 | Cuiffi et al. |
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FUNDED BY |
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APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts); The Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Joseph Cuiffi (Fort Myers, Florida); Jeffrey T. Borenstein (Newton, Massachusetts); Anilkumar Harapanahalli Achyuta (Tampa, Florida); Mark J. Mescher (West Newton, Massachusetts); Linda Griffith (Cambridge, Massachusetts); Samuel Walker Inman (Boston, Massachusetts) |
ABSTRACT | The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of tissue types in a biomimetic environment. By culturing organ specific tissue types within a biomimetic environment and interconnecting each of the organ systems in a physiologically meaningful way, experiments can be conducted on in vitro cells that substantially mimic the responses of in vivo cell populations. In some implementations, the system is used to monitor how organ systems respond to agents such as toxins or medications. The system enables the precise and controlled delivery of these agents, which, in some implementations, enables the biomimetic dosing of drugs in humans to be mimicked. |
FILED | Thursday, July 25, 2013 |
APPL NO | 13/951067 |
ART UNIT | 1799 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/12 (20130101) C12M 23/44 (20130101) Original (OR) Class C12M 23/48 (20130101) C12M 23/58 (20130101) C12M 29/00 (20130101) C12M 41/00 (20130101) C12M 41/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528144 | Bisso et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Paul Bisso (Belmont, Massachusetts); Albert Swiston (Baltimore, Maryland); Jiseok Lee (Melrose, Massachusetts); Patrick S. Doyle (Sudbury, Massachusetts) |
ABSTRACT | Polymer microparticles spatially and spectrally encoded using upconversion nanocrystals (UCN) are described for labeling of articles and tissues. UCN having spectrally distinguishable emission spectra are disposed in different portions of an encoding region of each microparticle. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/214528 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/0026 (20130101) G07D 7/122 (20130101) G07D 7/2033 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/13 (20150115) Y10T 436/143333 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528145 | Bisso et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Paul Bisso (Belmont, Massachusetts); Albert Swiston (Baltimore, Maryland); Jiseok Lee (Melrose, Massachusetts); Patrick S. Doyle (Sudbury, Massachusetts) |
ABSTRACT | Hydrogel microparticles spatially and spectrally encoded using upconverting phosphor nanoparticles are described for use in biochemical testing. In each microparticle, upconversion nanocrystals having spectrally distinguishable emission spectra are disposed in different pardons of an encoding region of the microparticle. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/214594 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/0026 (20130101) G07D 7/122 (20130101) G07D 7/2033 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/13 (20150115) Y10T 436/143333 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528491 | Hench et al. |
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FUNDED BY |
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APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
INVENTOR(S) | Steven C. Hench (Annapolis, Maryland); Charles R. Fralick (Ashburn, Virginia) |
ABSTRACT | Wave energy conversion systems are provided utilizing a mass of water entrained in a collapsible water mass enclosure that is suspended beneath a float (e.g., a vehicle, buoy, platform, etc.) to provide an inertial force in opposition to the rising heave-induced acceleration of the float. The water mass enclosure is communication with a generator, such as by tethering one end of a tethering means to the generator and the other to the enclosure. The enclosure may be placed in communication with an intermediary hydraulic system, which is also in communication with the generator. In certain embodiments, the system will include a reel system for deploying and retrieving the water masse enclosure. |
FILED | Friday, October 03, 2014 |
APPL NO | 14/506016 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Hydraulic Engineering E02B 9/08 (20130101) Machines or Engines for Liquids F03B 13/20 (20130101) Original (OR) Class Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2240/93 (20130101) F05B 2260/406 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 11/08 (20130101) F15B 2211/2053 (20130101) F15B 2211/7058 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528801 | Gold |
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FUNDED BY |
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APPLICANT(S) | Vladimir M. Gold (Hillside, New Jersey) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Vladimir M. Gold (Hillside, New Jersey) |
ABSTRACT | A flexible warhead which can be used for a bunker defeat mechanism. The warhead has a polysterene membrane embedded with lethal tungsten alloy fragments, contains an explosive gel, and also has an attached time delay fuze. The warhead is folded and stored in a case. In use, the warhead is expelled from the case by a propellant and the membrane is exploded with its fragments proximate to impacting a target, after the time delay. |
FILED | Monday, September 14, 2015 |
APPL NO | 14/853258 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/20 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528802 | Markowitch et al. |
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FUNDED BY |
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APPLICANT(S) | Michael Markowitch (Rockaway, New Jersey); Francesco Rizzi (Hopatcong, New Jersey); Bryan Drake (Great Meadows, New Jersey); Jason Surmanek (Franklin Lakes, New Jersey); Samuel Perez (Hackettstown, New Jersey); Raymond Trohanowsky (Franklin, New Jersey); Wooje Na (Ridgefield, New Jersey); Piotr Czerechowski (Rockaway, New Jersey) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Michael Markowitch (Rockaway, New Jersey); Francesco Rizzi (Hopatcong, New Jersey); Bryan Drake (Great Meadows, New Jersey); Jason Surmanek (Franklin Lakes, New Jersey); Samuel Perez (Hackettstown, New Jersey); Raymond Trohanowsky (Franklin, New Jersey); Wooje Na (Ridgefield, New Jersey); Piotr Czerechowski (Rockaway, New Jersey) |
ABSTRACT | An indirect fire munition non-lethal cargo carrier mortar deploys non-lethal sub-munitions to an intended target. The cargo carrier mortar includes a deceleration system which allows for the discarded mortar to descend at a controlled non-free fall velocity thereby minimizing the risk of injury or collateral damage from the mortar. The cargo carrier mortar is adapted to be compatible with existing standard military equipment such as standard mortar caliber sizes. |
FILED | Thursday, November 19, 2015 |
APPL NO | 14/946118 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/56 (20130101) F42B 12/36 (20130101) Original (OR) Class F42B 30/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528803 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Steven Kim (Crofton, Maryland); Conan Schultz (Waldorf, Maryland); Carl Gotzmer (Accokeek, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Steven Kim (Crofton, Maryland); Conan Schultz (Waldorf, Maryland); Carl Gotzmer (Accokeek, Maryland) |
ABSTRACT | An incendiary grenade's casing has a fuze with a portion extending into the casing. Thermite disposed in the casing encases the portion of the fuze that extends into the grenade casing. Insulating material is disposed in the casing adjacent to the thermite. Layers of a titanium-boron intermetallic and an oxidizer are disposed in the casing. One layer of the titanium-boron intermetallic is adjacent to the layer of insulating material. This one layer of the titanium-boron intermetallic and a layer of the oxidizer adjacent thereto have a common-axis hole formed therethrough that is aligned with the portion of the fuze. A separating material is disposed at each interface between the titanium-boron intermetallic and the oxidizer. |
FILED | Thursday, August 15, 2013 |
APPL NO | 13/987619 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 4/26 (20130101) F42B 12/44 (20130101) Original (OR) Class F42B 12/46 (20130101) F42B 27/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528809 | Cahayla et al. |
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FUNDED BY |
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APPLICANT(S) | Jason R. Cahayla (West Milford, New Jersey); Stephen Redington (Wharton, New Jersey); Barry Schwartz (Newton, New Jersey); Lloyd Khuc (Wharton, New Jersey) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jason R. Cahayla (West Milford, New Jersey); Stephen Redington (Wharton, New Jersey); Barry Schwartz (Newton, New Jersey); Lloyd Khuc (Wharton, New Jersey) |
ABSTRACT | A setback switch device is provided which, upon launch, can arm an explosive or pyrotechnic device for military gun launched applications. An included bridgewire shunt feature can also prevent the unintended arming, or accidental arming by a stray voltage before any launch is undertaken, of such explosive or pyrotechnic device. |
FILED | Tuesday, September 01, 2015 |
APPL NO | 14/842269 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528826 | Garvey et al. |
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FUNDED BY |
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APPLICANT(S) | GRALE TECHNOLOGIES (Youngstown, Ohio) |
ASSIGNEE(S) | GRALE TECHNOLOGIES (Youngstown, Ohio) |
INVENTOR(S) | Michael Garvey (Canfield, Ohio); James D. Osterloh (West Richland, Washington); Fred Persi (Akuqyuooa, Pennsylvania) |
ABSTRACT | Systems, apparatuses and methods are described for integrating an electronic metrology sensor with precision production equipment such as computer numerically controlled (CNC) machines. For example, a laser distance measuring sensor is used. Measurements are taken at a relatively high sample rate and converted into a format compatible with other data generated or accepted by the CNC machine. Measurements from the sensor are synchronized with the position of the arm of the machine such as through the use of offsets. Processing yields a detailed and highly accurate three-dimensional map of a workpiece in the machine. Applicable metrology instruments include other near continuously reading non-destructive characterization instruments such as contact and non-contact dimensional, eddy current, ultra-sound, and X-Ray Fluorescence (XRF) sensors. |
FILED | Wednesday, November 04, 2015 |
APPL NO | 14/932036 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/04 (20130101) G01B 21/16 (20130101) Original (OR) Class Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/401 (20130101) G05B 2219/37198 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528925 | Kletter et al. |
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FUNDED BY |
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APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
ASSIGNEE(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
INVENTOR(S) | Doron Kletter (San Mateo, California); Joerg Martini (San Francisco, California); Marshall W. Bern (San Carlos, California); Noble M. Johnson (Menlo Park, California); Peter Kiesel (Palo Alto, California); Bowen Cheng (Atherton, California); Michael I. Recht (Mountain View, California) |
ABSTRACT | Approaches for determining object position in a flow path are disclosed. A system includes a spatial filter having a length disposed along a longitudinal axis of the flow path and a width along a lateral axis of the flow path. The spatial filter has mask features configured to modulate light. Light emanating from objects moving along the flow path is detected. The detected light has a component along a detection axis that makes a non-zero angle with respect to the longitudinal and lateral axes. An electrical output signal that includes information about the trajectory depth of the object is generated in response to the detected light. |
FILED | Friday, February 14, 2014 |
APPL NO | 14/181560 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1459 (20130101) Original (OR) Class G01N 2015/0038 (20130101) G01N 2015/0053 (20130101) G01N 2015/1006 (20130101) G01N 2021/8592 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528929 | Chenault |
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FUNDED BY |
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APPLICANT(S) | Polaris Sensor Technologies, Inc. (Huntsville, Alabama) |
ASSIGNEE(S) | POLARIS SENSOR TECHNOLOGIES, INC. (Huntsville, Alabama) |
INVENTOR(S) | David B. Chenault (Huntsville, Alabama) |
ABSTRACT | A method using Infrared Imaging Polarimetry for detecting the presence of foreign fluids on water comprises estimating an expected polarization response for a foreign fluid desired to be detected. Oil from an oil spill is one such foreign fluid. An optimal position of a polarimeter to take images of the water's surface is determined from the expected polarization response. The polarimeter is positioned at the optimal position and records raw image data of the water's surface to obtain polarized images of the area. The polarized images are corrected, and IR and polarization data products are computed. The IR and polarization data products are converted to multi-dimensional data set to form multi-dimensional imagery. Contrast algorithms are applied to the multi-dimensional imagery to form enhanced contrast images, from which foreign fluids can be automatically detected. |
FILED | Wednesday, September 02, 2015 |
APPL NO | 14/843835 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) Original (OR) Class G01N 2021/1793 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528982 | Lancaster et al. |
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FUNDED BY |
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APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
INVENTOR(S) | Johnathan Lancaster (Tampa, Florida); Douglas Marchion (Seminole, Florida); Dung-Tsa Chen (Tampa, Florida) |
ABSTRACT | Despite initial sensitivity BAD-protein phosphorylation were evaluated in patient samples and cell lines as determinants of chemo-sensitivity and/or clinical outcome, and as therapeutic targets. Induced in-vitro OVCA cisplatin-resistance was associated with BAD-pathway expression. Expression of the pathway was also associated with resistance of 7 different cancers cell-types to 8 chemotherapeutic agents. Phosphorylation of the BAD-protein was associated with platinum-resistance in OVCA cells and primary OVCA specimens, and also overall patient survival. Targeted modulation of BAD-phosphorylation levels influenced cisplatin-sensitivity. A 47-gene BAD-pathway signature was associated in-vitro phospho-BAD levels and with survival of 838 patients with ovarian, breast, colon, and brain cancer. The survival advantage associated with both BAD-phosphorylation and also the BAD-pathway signature was independent of surgical cytoreductive status. The BAD apoptosis pathway influences human cancer chemo-sensitivity and overall survival. The pathway is useful as a biomarker of therapeutic response, patient survival, and therapeutic target. |
FILED | Monday, August 26, 2013 |
APPL NO | 14/010003 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) Original (OR) Class G01N 33/57449 (20130101) G01N 2440/14 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529150 | Orcutt et al. |
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FUNDED BY |
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APPLICANT(S) | Jason Scott Orcutt (Katonah, New York); Karan Kartik Mehta (Cambridge, Massachusetts); Rajeev Jagga Ram (Arlington, Massachusetts); Amir Hossein Atabaki (Medford, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Jason Scott Orcutt (Katonah, New York); Karan Kartik Mehta (Cambridge, Massachusetts); Rajeev Jagga Ram (Arlington, Massachusetts); Amir Hossein Atabaki (Medford, Massachusetts) |
ABSTRACT | Conventional approaches to integrating waveguides within standard electronic processes typically involve using a dielectric layer, such as polysilicon, single-crystalline silicon, or silicon nitride, within the in-foundry process or depositing and patterning a dielectric layer in the backend as a post-foundry process. In the present approach, the back-end of the silicon handle is etched away after in-foundry processing to expose voids or trenches defined using standard in-foundry processing (e.g., complementary metal-oxide-semiconductor (CMOS) processing). Depositing dielectric material into a void or trench yields an optical waveguide integrated within the front-end of the wafer. For example, a shallow trench isolation (STI) layer formed in-foundry may serve as a high-resolution patterning waveguide template in a damascene process within the front end of a die or wafer. Filling the trench with a high-index dielectric material yields a waveguide that can guide visible and/or infrared light, depending on the waveguide's dimensions and refractive index contrast. |
FILED | Wednesday, October 22, 2014 |
APPL NO | 14/520893 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) Original (OR) Class G02B 6/132 (20130101) G02B 6/136 (20130101) G02B 6/305 (20130101) G02B 6/1225 (20130101) G02B 6/12004 (20130101) G02B 2006/121 (20130101) G02B 2006/12097 (20130101) G02B 2006/12107 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0147 (20130101) G02F 2001/0151 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529191 | Sverdrup et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence H. Sverdrup (Poway, California); Mikhail Belenkii (San Diego, California) |
ASSIGNEE(S) | Trex Enterprises Corporation (San Diego, California) |
INVENTOR(S) | Lawrence H. Sverdrup (Poway, California); Mikhail Belenkii (San Diego, California) |
ABSTRACT | A head mounted display system with at least one retinal display unit having a curved reflector positioned in front of one eye or both eyes of a wearer. The unit includes a first set of three modulated visible-light lasers co-aligned and adapted to provide a laser beam with selectable color and a first scanner unit providing both horizontal and vertical scanning of the laser beam across a portion of the curved reflector in directions so as to produce a reflection of the color laser beam through the pupil of the eye onto a portion of the retina large enough to encompass the fovea. The unit also includes a second set three modulated visible-light lasers plus an infrared laser, all lasers being co-aligned and adapted to provide a color and infrared peripheral view laser beam, and a second scanner unit providing both horizontal and vertical scanning of the visible light and infrared laser beams across a portion of the curved reflector in directions so as to produce a reflection of the scanned color and infrared laser beams through the pupil of the eye onto a portion of retina corresponding to a field of view of at least 30 degrees×30 degrees. |
FILED | Wednesday, November 03, 2010 |
APPL NO | 12/925974 |
ART UNIT | 2628 — Selective Visual Display Systems |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 27/0093 (20130101) Original (OR) Class G02B 27/0172 (20130101) G02B 2027/015 (20130101) G02B 2027/0123 (20130101) G02B 2027/0147 (20130101) G02B 2027/0187 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09529357 — Method and apparatus for operator supervision and direction of highly autonomous vehicles
US 09529357 | Eggers et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey Eggers (Leesburg, Virginia); Mark Draper (Beavercreek, Ohio); Robert Shaw (Beavercreek, Ohio); Joshua Hamell (San Marcos, California); Heath Ruff (Dayton, Ohio) |
ABSTRACT | A system for automating the control of a Remotely Piloted Vehicle (RPV) includes a computer having a processor and a memory, a display operatively coupled to the computer and configured to display a future operating condition of the RPV and an input device operatively coupled to the computer. A predicted noodle tool is executed by the processor and configured to indicate a predicted future path of the RPV by generating a predicted noodle segment on the display. A directed noodle tool is executed by the processor to indicate a pilot-adjustable proposed future flight path of the RPV by generating a directed noodle segment on the display. Further, an input device mode selector is operatively coupled to the processor and configured to selectively map the input device to either manipulate a control surface of the RPV, or to manipulate the directed noodle segment. |
FILED | Monday, June 09, 2014 |
APPL NO | 14/298992 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0011 (20130101) Original (OR) Class G05D 1/0027 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529590 | Song |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | William S. Song (Lexington, Massachusetts) |
ABSTRACT | A node processor and method for performing matrix operations includes storing, in memory, non-zero matrix elements of a first sparse matrix, non-zero matrix elements of a second sparse matrix, and matrix elements of a sparse results matrix mapped to the node processor. A matrix communications module exchanges with other node processors, non-zero matrix elements of one or more of the first sparse matrix, second sparse matrix, and sparse results matrix. An arithmetic logic unit generates partial results based on the non-zero matrix elements of the first sparse matrix and on the non-zero matrix elements of the second sparse matrix stored in memory. The arithmetic logic unit further generates a final value for each matrix element of the sparse results matrix mapped to the node processor based on the partial results generated by the arithmetic logic unit and on partial results received from the other node processors. |
FILED | Monday, May 19, 2014 |
APPL NO | 14/281132 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 9/3001 (20130101) Original (OR) Class G06F 17/10 (20130101) G06F 17/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529614 | Lin et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents The University of Texas Systems (Austin, Texas) |
INVENTOR(S) | Zhiqiang Lin (Dallas, Texas); Yangchun Fu (Dallas, Texas) |
ABSTRACT | Disclosed are various embodiments that facilitate automatically bridging the semantic gap in machine introspection. It may be determined that a program executed by a first virtual machine is requested to introspect a second virtual machine. A system call execution context of the program may be determined in response to determining that the program is requested to introspect the second virtual machine. Redirectable data in a memory of the second virtual machine may be identified based at least in part on the system call execution context of the program. The program may be configured to access the redirectable data. In various embodiments, the program may be able to modify the redirectable data, thereby facilitating configuration, reconfiguration, and recovery operations to be performed on the second virtual machine from within the first virtual machine. |
FILED | Tuesday, March 05, 2013 |
APPL NO | 14/382259 |
ART UNIT | 2199 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/3004 (20130101) G06F 9/45533 (20130101) Original (OR) Class G06F 9/45558 (20130101) G06F 11/3466 (20130101) G06F 21/55 (20130101) G06F 2009/45587 (20130101) G06F 2201/815 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529953 | Kamin et al. |
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FUNDED BY |
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APPLICANT(S) | Nackieb M. Kamin (Kapolei, Hawaii); Gregory Lum (Honolulu, Hawaii); Henry Au (Honolulu, Hawaii) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Nackieb M. Kamin (Kapolei, Hawaii); Gregory Lum (Honolulu, Hawaii); Henry Au (Honolulu, Hawaii) |
ABSTRACT | A subthreshold standard cell library addresses the energy efficiency of electronic systems, thereby significantly reducing power consumption. Recent energy performance requirements are causing the next-generation system manufacturers to explore approaches to lower power consumption. Subthreshold operation has been examined and implemented in designing ultra-low power standard cell designs that operate beyond the normal modes of operation, with the potential for large energy savings. Operation of CMOS (Complementary Metal Oxide Semiconductor) transistors in the subthreshold regime, where the supply voltage used in operation is orders of magnitude below the normal operating voltage of typical transistors, has proven to be very beneficial for energy constrained systems as it enables minimum energy consumption in Application Specific Integrated Circuits (ASICs). |
FILED | Monday, February 22, 2016 |
APPL NO | 15/049762 |
ART UNIT | 2851 — Printing/Measuring and Testing |
CURRENT CPC | Electric Digital Data Processing G06F 17/504 (20130101) G06F 17/505 (20130101) Original (OR) Class G06F 17/5031 (20130101) G06F 17/5068 (20130101) G06F 17/5081 (20130101) G06F 2217/84 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529974 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Peter C. Li (McLean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Alexandria, Virginia); James M. Wilson (Cedaredge, Colorado); Jae I. Yoon (Centreville, Virginia); Manabu Torii (Newark, Delaware); Carla S. Thomas (Bodega Bay, California) |
ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
INVENTOR(S) | Peter C. Li (McLean, Virginia); Jeffrey R. Collmann (Washington, District of Columbia); Jane W. Blake (Alexandria, Virginia); Mark G. Polyak (Alexandria, Virginia); James M. Wilson (Cedaredge, Colorado); Jae I. Yoon (Centreville, Virginia); Manabu Torii (Newark, Delaware); Carla S. Thomas (Bodega Bay, California) |
ABSTRACT | A system and method involves detecting operational social disruptive events on a global scale, assigning event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling propagation of events for containment and forecasting purposes. |
FILED | Wednesday, July 27, 2011 |
APPL NO | 13/192160 |
ART UNIT | 2451 — Computer Networks |
CURRENT CPC | Electric Digital Data Processing G06F 17/30616 (20130101) G06F 19/3493 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 50/22 (20130101) G06Q 50/26 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/08072 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530048 | Bartlett et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (La Jolla, California); The Research Foundation of State University of New York (Amherst, New York) |
ASSIGNEE(S) | The Regents Of The University Of California (Oakland, California); The Research Foundation of State University of New York (Amherst, New York) |
INVENTOR(S) | Marian Stewart Bartlett (San Diego, California); Gwen Littlewort-Ford (Solana, California); Javier Movellan (La Jolla, California); Ian Fasel (Tuscan, Arizona); Mark Frank (Amherst, New York) |
ABSTRACT | An automatic facial action coding system and method can include processing an image to identify a face in the image, to detect and align one or more facial features shown in the image, and to define one or more windows on the image. One or more distributions of pixels and color intensities can be quantified in each of the one or more windows to derive one or more two-dimensional intensity distributions of one or more colors within the window. The one or more two-dimensional intensity distributions can be processed to select image features appearing in the one or more windows and to classify one or more predefined facial actions on the face in the image. A facial action code score that includes a value indicating a relative amount of the predefined facial action occurring in the face in the image can be determined for the face in the image for each of the one or more predefined facial actions. |
FILED | Monday, June 23, 2014 |
APPL NO | 14/311814 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00281 (20130101) G06K 9/00288 (20130101) G06K 9/00315 (20130101) G06K 9/00335 (20130101) Original (OR) Class G06K 9/4652 (20130101) G06K 9/6256 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530052 | Pillai et al. |
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FUNDED BY |
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APPLICANT(S) | Jaishanker K. Pillai (College Park, Maryland); Maria Puertas-Calvo (Arlington, Virginia); Ramalingam Chellappa (Potomac, Maryland) |
ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
INVENTOR(S) | Jaishanker K. Pillai (College Park, Maryland); Maria Puertas-Calvo (Arlington, Virginia); Ramalingam Chellappa (Potomac, Maryland) |
ABSTRACT | The sensor adaptation technique applicable to non-contact biometric authentication, specifically in iris recognition, is designed to handle the sensor mismatch problem which occurs when enrollment iris samples and test iris samples are acquired with different sensors. The present system and method are capable of adapting iris data collected from one sensor to another sensor by transforming the iris samples in a fashion bringing the samples belonging to the same person closer than those samples belonging to different persons, irrespective of the sensor acquiring the samples. The sensor adaptation technique is easily incorporable into existing iris recognition systems and uses the training iris samples acquired with different sensors for learning adaptation parameters and subsequently applying the adaptation parameters for sensor adaptation during verification stage to significantly improve the recognition system performance. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/209042 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0061 (20130101) G06K 9/00604 (20130101) G06K 9/00617 (20130101) Original (OR) Class G06K 9/6257 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09530101 — Method for calculating sensor performance of a sensor grid using dynamic path aggregation
US 09530101 | Hyland et al. |
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FUNDED BY |
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APPLICANT(S) | John C. Hyland (Panama City, Florida); Cheryl M. Smith (Panama City, Florida) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | John C. Hyland (Panama City, Florida); Cheryl M. Smith (Panama City, Florida) |
ABSTRACT | A technique is provided for determining expected maximum probability of detection of targets moving through a sensor grid to maximize performance of the sensor grid by changing the sensor grid variables. Non-spatial variables from a plurality of sensors of the sensor grid are removed to provide that sensor performance of the plurality of sensors is a function of spatial variables. A selection is made for the desired description of flow of targets such as pedestrians through the sensor grid between restricted stochastic flow and unrestricted stochastic flow. The specific technique and related equations for determining expected maximum probability of detection for each sensor depends on whether restricted stochastic flow or unrestricted stochastic flow is selected. |
FILED | Wednesday, November 20, 2013 |
APPL NO | 14/085277 |
ART UNIT | 2683 — Telemetry and Code Generation Vehicles and System Alarms |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Original (OR) Class G06N 7/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530193 | Debevec et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Paul E. Debevec (Culver City, California); Timothy S. Hawkins (Marina del Rey, California); Chris D. X. N. Tchou (Kirkland, Washington) |
ABSTRACT | A high dynamic range image editing system for editing an image file having pixels spanning a first range of light intensity levels in an image editing system that only displays differences in the light intensity levels of pixels within a second range of light intensity levels that is less than the first range of light intensity levels, without reducing the range of light intensity levels in the image file. |
FILED | Thursday, November 21, 2013 |
APPL NO | 14/086231 |
ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Image Data Processing or Generation, in General G06T 5/007 (20130101) Original (OR) Class G06T 5/009 (20130101) G06T 11/001 (20130101) G06T 2207/20208 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/02 (20130101) G09G 5/06 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 27/034 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530535 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Xiao Liu (Fairfax, Virginia); Daniel R. Queen (Silver Spring, Maryland); Frances Hellman (Berkeley, California) |
ABSTRACT | A hydrogen-free amorphous dielectric insulating film having a high material density and a low density of tunneling states is provided. The film is prepared by e-beam deposition of a dielectric material on a substrate having a high substrate temperature Tsub under high vacuum and at a low deposition rate. In an exemplary embodiment, the film is amorphous silicon having a density greater than about 2.18 g/cm3 and a hydrogen content of less than about 0.1%, prepared by e-beam deposition at a rate of about 0.1 nm/sec on a substrate having Tsub=400° C. under a vacuum pressure of 1×10−8 Torr. |
FILED | Wednesday, November 12, 2014 |
APPL NO | 14/538968 |
ART UNIT | 2896 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/40 (20130101) C21D 1/773 (20130101) C21D 2201/03 (20130101) Alloys C22C 45/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/06 (20130101) C23C 14/14 (20130101) C23C 14/541 (20130101) C23C 14/0605 (20130101) C23C 14/0652 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/02 (20130101) Original (OR) Class H01B 19/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0226 (20130101) H01L 21/02107 (20130101) H01L 21/02269 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530574 | Phillips et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jonathan Phillips (Pacific Grove, California); Samuel Salvadore Fromille (Kapolei, Hawaii) |
ABSTRACT | A class of materials is provided that has dielectric constants greater than 105. The super dielectric materials (SDM) can be generated readily from common, inexpensive materials. Various embodiments include a porous, electrically insulating material, such as high surface area powders of silica or titantia, mixed with a liquid containing a high concentration of ionic species. In some embodiments, high surface area alumina powders, loaded to the incipient wetness point with a solution of boric acid dissolved in water, have dielectric constants greater than 4*108. |
FILED | Tuesday, February 17, 2015 |
APPL NO | 14/624321 |
ART UNIT | 2848 — Electrical Circuits and Systems |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/10 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/60 (20130101) Original (OR) Class H01G 11/62 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530911 | King et al. |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Seal Beach, California) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Richard R. King (Thousand Oaks, California); Christopher M. Fetzer (VAlencia, California); Daniel C. Law (Arcadia, California); Xing-Quan Liu (Arcadia, California); William D. Hong (Los Angeles, California); Kenneth M. Edmondson (Burbank, California); Dimitri D. Krut (Encino, California); Joseph C. Boisvert (Thousand Oaks, California); Nasser H. Karam (La Canada, California) |
ABSTRACT | In one aspect, optoelectronic devices are described herein. In some implementations, an optoelectronic device comprises a photovoltaic cell. The photovoltaic cell comprises a space-charge region, a quasi-neutral region, and a low bandgap absorber region (LBAR) layer or an improved transport (IT) layer at least partially positioned in the quasi-neutral region of the cell. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/831056 |
ART UNIT | 1756 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0352 (20130101) H01L 31/0687 (20130101) H01L 31/035209 (20130101) H01L 31/035272 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530965 | Gleason et al. |
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FUNDED BY |
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APPLICANT(S) | Karen K. Gleason (Cambridge, Massachusetts); Sung Gap Im (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Karen K. Gleason (Cambridge, Massachusetts); Sung Gap Im (Cambridge, Massachusetts) |
ABSTRACT | One aspect of the invention relates to a linker-free, one-step method of grafting polymer films onto organic substrates, and the films obtained by such a method. In certain embodiments, the grafted polymer films are conductive. In certain embodiments, said grafting method utilizes the ability for Friedel-Crafts catalyst to form radical cations from organic substrates. In one embodiment, the method provides poly-3,4-ethylenedioxythiophene (PEDOT) thin films grafted to organic substrates. In other embodiments, the method is applicable to the polymerization of other monomers to yield conducting polymers, such as polyanilines, polypyrroles, polyfurans, polythiophenes and their derivatives. Remarkably, the polymer films grafted by the inventive methods show enormous increases in adhesion strength. Further, in certain embodiments, polymer patterns were easily obtained using the inventive methods and soft lithography techniques. In certain embodiments, well-defined high-density line-and-space patterns were successfully obtained. In certain embodiments, e.g., when the polymer film is conducting, the obtained conducting polymer pattern grafted on common organic substrates can be used for integrated circuitry in flexible electronics. |
FILED | Tuesday, July 15, 2014 |
APPL NO | 14/331891 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) B05D 1/185 (20130101) B05D 3/10 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/124 (20130101) C08G 61/125 (20130101) C08G 61/126 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 165/00 (20130101) C09D 179/02 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2001/1515 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0037 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531027 | Tender |
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FUNDED BY |
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APPLICANT(S) | Leonard M. Tender (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Leonard M. Tender (Bethesda, Maryland) |
ABSTRACT | Systems and methods are presented for generating and storing electric power in which a microbial solar cell is provided in a sealed container with photosynthetic organisms that generate reactants of the microbial fuel cell and the products of the microbial fuel cell from sunlight received through the container. |
FILED | Tuesday, March 02, 2010 |
APPL NO | 12/716118 |
ART UNIT | 1758 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) Original (OR) Class H01M 8/0606 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/527 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531055 | Abraham et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | David W. Abraham (Croton-On-Hudson, New York); Jerry M. Chow (White Plains, New York); Antonio D. Corcoles Gonzalez (Mount Kisco, New York); George A. Keefe (Cortlandt Manor, New York); Mary E. Rothwell (Ridgefield, Connecticut); James R. Rozen (Peekskill, New York); Matthias Steffen (Cortlandt Manor, New York) |
ABSTRACT | A coplanar waveguide device includes a coplanar waveguide structure disposed on a substrate, at least one qubit coupled to the coplanar waveguide structure and an add-on chip having a metallized trench, and disposed over the substrate. |
FILED | Friday, January 30, 2015 |
APPL NO | 14/610476 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/223 (20130101) H01L 39/2406 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/003 (20130101) H01P 3/026 (20130101) H01P 7/086 (20130101) Original (OR) Class H01P 11/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531150 | Ozdemir et al. |
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FUNDED BY |
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APPLICANT(S) | Washington University (Saint Louis, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Sahin Kaya Ozdemir (Saint Louis, Missouri); Bo Peng (Saint Louis, Missouri); Lan Yang (Saint Louis, Missouri) |
ABSTRACT | A method and system for optical systems based on parity-time symmetry and its breaking, and for nonreciprocal light transmission in a parity-time symmetric micro-resonator system are provided. The system includes an optical assembly that includes a first dissipative optical system and a second optical system coupled in energy transfer communication with the first optical system. The second optical system is configured to receive a continuous flow of energy from an external source and to transfer energy to the first optical system through the couple wherein the energy transferred to the first optical system from the second optical system is approximately equal to the energy dissipated in the first optical system, where the energy transferred to the first optical system from the second optical system is selectable using at least one of an amount of couple between the first optical system and the second optical system and a gain of the second optical system. |
FILED | Monday, April 13, 2015 |
APPL NO | 14/685335 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 2203/15 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/082 (20130101) H01S 3/176 (20130101) H01S 3/0604 (20130101) H01S 3/0627 (20130101) H01S 3/1608 (20130101) H01S 3/10092 (20130101) Original (OR) Class H01S 3/094038 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531302 | Cochran et al. |
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FUNDED BY |
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APPLICANT(S) | Kevin Cochran (Falls Church, Virginia); Daniel Jean (Odenton, Maryland); Ezra Chen (Bowie, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Kevin Cochran (Falls Church, Virginia); Daniel Jean (Odenton, Maryland); Ezra Chen (Bowie, Maryland) |
ABSTRACT | A ratcheting micromotor includes a ratchet bar defining ratchet teeth along an edge thereof, and first and second ends in opposition to one another. The first end is adapted to be coupled to an object to be moved. A spring is coupled on one end thereof to the second end of the ratchet bar and adapted to be fixed at another end thereof to a base. A bi-directional actuator configured for linear movement in one of a first direction and a second direction, and when energized has a common yoke coupled to a central portion thereof for movement in correspondence therewith. The common yoke includes teeth formed along an edge and positioned such that its teeth engage a portion of the ratchet teeth. A control system energizes the bi-directional actuator to move, alternately, in the first direction and the second direction. |
FILED | Wednesday, November 27, 2013 |
APPL NO | 13/998722 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 2/021 (20130101) Original (OR) Class H02N 2/043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531324 | Delos et al. |
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FUNDED BY |
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APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Peter L. Delos (Mt. Laurel, New Jersey); Francis X. McGroary (Brick, New Jersey); Edward F. Gross (Swedesboro, New Jersey) |
ABSTRACT | A frequency synthesizing circuit comprising a first mixer configured to receive a first input signal at a first input thereof, a first filter configured to receive an output signal of the first mixer and remove undesired signal frequencies from the output signal of the first mixer, and a feedback loop. The feedback loop includes a second mixer having a first input connected to the output of the first filter and a second input for receiving a second input signal. The second mixer is configured to mix a signal received at the first input with the second input signal. The feedback loop further includes a third mixer having a first input connected to an output of the second mixer and a second input for receiving a third input signal. The third mixer is configured to mix a signal received at the first input with the third input signal. |
FILED | Wednesday, July 01, 2015 |
APPL NO | 14/788958 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 19/12 (20130101) Original (OR) Class Pulse Technique H03K 3/013 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531356 | Delos et al. |
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FUNDED BY |
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APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Peter L. Delos (Mount Laurel, New Jersey); Brandon R. Davis (Mount Laurel, New Jersey); Steven M. Fireman (Wallingford, Pennsylvania) |
ABSTRACT | An integrated circuit includes a clock distribution circuit and a logic block circuit. The clock distribution circuit is segregated from the logic block circuit to restrict contributors to phase noise to the clock distribution section of the circuit. The clock distribution circuit includes a front-end amplifier which buffers a clock input signal to a differential clock signal. The front-end amplifier is configured with as few components as possible and the components are selected for high current density and sized to minimize contributions to phase noise in the clock distribution circuit. The clock distribution circuit further includes an output latch circuit that receives the output signal of the logic block circuit and the low phase noise differential clock input signal from the front-end amplifier circuit. The output latch circuit re-clocks the final output of the integrated circuit. The output is representative of the output values determined by the logic block circuit. |
FILED | Monday, October 13, 2014 |
APPL NO | 14/512917 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Pulse Technique H03K 5/00006 (20130101) Original (OR) Class H03K 5/13 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531623 | Besaw et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Nathan A. Besaw (Defiance, Ohio); Bret G. Bidwell (Hopewell Junction, New York); John Dorfner (Rhinebeck, New York); Aruna V. Ramanan (Poughkeepsie, New York) |
ABSTRACT | Embodiments relate to setting up direct mapped routers located across independently managed compute and storage networks for enabling multiple modes of communication over the cross-coupled links between the networks. An aspect includes identifying a characteristic of a local entity based on a unique location identifier assigned to the local entity and learning a characteristic of a remote entity based on a location identifier received over a cross-coupled link between the local entity and the remote entity. A port on a local entity router is then correlated with the received location identifier of the remote entity. A route is then built in the direct mapped router table at a location pointed to by the location identifier of the remote entity. An optimistic failover route is established from a storage entity to a compute entity when a cross-coupled link between the storage entity and the compute entity is broken. |
FILED | Friday, April 05, 2013 |
APPL NO | 13/857333 |
ART UNIT | 2452 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0654 (20130101) H04L 45/22 (20130101) Original (OR) Class H04L 45/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531689 | Romero-Mariona et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jose Romero-Mariona (San Diego, California); Tom Nguyen (San Diego, California); Mihail Schoolov (San Diego, California); Ashton Mozano (San Diego, California) |
ABSTRACT | A system and method involve determining that one or more data packets received from a first device on a communications network are one of data at rest and data in transit, performing one of an encryption operation and a decryption operation on the data packets, and storing the data packets in a memory device if they are data at rest or transmitting the data packets over the communications network if they are data in transit. If the data packets are data in transit, the method may involve, prior to transmission, encapsulating information into a frame of the data packets to indicate they are data in transit. The data packets may be compressed prior to encryption. The determination that the data packets are one of data at rest and data in transit may be based upon a value of at least one data field of the data packets. |
FILED | Thursday, January 15, 2015 |
APPL NO | 14/597349 |
ART UNIT | 2434 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/602 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/062 (20130101) H04L 63/0428 (20130101) H04L 63/0464 (20130101) H04L 63/0471 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531747 | Stavrou et al. |
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FUNDED BY |
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APPLICANT(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
ASSIGNEE(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
INVENTOR(S) | Angelos Stavrou (Springfield, Virginia); Sushil Jajodia (Oakton, Virginia); Anup K. Ghosh (Centreville, Virginia); Rhandi Martin (St. James, Barbados); Charalampos Andrianakis (Crete, Greece) |
ABSTRACT | A transparent proxy for malware detection includes a monitor module, a protocol determination module, a challenge generation module, a response determination module, and a data control module. The monitor module examines data originating from an application towards a remote server. The protocol determination module identifies the protocol type used for the data. The challenge generation module produces a challenge for the application based upon the protocol type, sends the challenge to the application, and maintains a state related to the data and the challenge. The response determination module makes a determination if an automatic non-interactive application response is received in response to the challenge from the application. The data control module allows the first data to continue to the remote server when the determination is valid. The data control module reports malware detection and blocks the data to continue to the remote server when the determination is invalid. |
FILED | Wednesday, September 10, 2014 |
APPL NO | 14/482793 |
ART UNIT | 2439 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/566 (20130101) G06F 2221/2103 (20130101) G06F 2221/2119 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/145 (20130101) Original (OR) Class H04L 63/0884 (20130101) H04L 63/1416 (20130101) H04L 67/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531780 | Leong et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Derek Leong (Pasadena, California); Asma Qureshi (Pasadena, California); Yunkai Wei (Pasadena, California); Tracey C Ho (Pasadena, California) |
ABSTRACT | A computer-based real-time streaming system under packet erasures wherein created messages can be decoded within a fixed delay form their creation is presented. Various code construction methods and corresponding hardware implementation for different cases of erasure link models are also presented. |
FILED | Thursday, November 14, 2013 |
APPL NO | 14/080686 |
ART UNIT | 2455 — Computer Networks |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/23 (20130101) H03M 13/293 (20130101) H03M 13/356 (20130101) H03M 13/373 (20130101) H03M 13/1515 (20130101) H03M 13/2721 (20130101) H03M 13/2909 (20130101) H03M 13/2921 (20130101) H03M 13/3761 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 65/607 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 19/67 (20141101) H04N 19/89 (20141101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09532031 | Bendall |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
INVENTOR(S) | Charles S. Bendall (, None) |
ABSTRACT | A method involves mounting a laser on a rotation device with azimuth and elevation degrees of freedom, locating the rotation device at a distance from the locations of two or more cameras, orienting each camera so the origin of a laser beam is imaged onto each camera, measuring the distance between each camera origin and the laser aperture, projecting the laser beam through a sequence of precisely determined azimuth and elevation orientations, using each camera collecting laser beam images as the laser is projected through the sequence, and using the laser beam images to determine a set of rotation matrices R and translation vectors T. Using R and T, a point in a laser coordinate frame is translated into a coordinate frame of each of the cameras or a point in a coordinate frame of one camera is translated into a coordinate frame of another camera. |
FILED | Tuesday, April 08, 2014 |
APPL NO | 14/247969 |
ART UNIT | 2483 — Recording and Compression |
CURRENT CPC | Pictorial Communication, e.g Television H04N 13/0022 (20130101) H04N 13/0246 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09532150 | Blick et al. |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Robert H. Blick (Madison, Wisconsin); Burke S. Richmond (Madison, Wisconsin) |
ABSTRACT | A flexible membrane of piezoelectric material sized to be supported by and to conform to the eardrum. Electrodes on the membrane allow the membrane to function as an audio transducer stimulating the eardrum with an audio signal or detecting audio signals at the eardrum. Applications may include detecting a variety of pathophysiological and biomechanical features of the tissues of the tympanic membrane and regional integrated anatomy, detecting audio, physical and biological signals, and/or delivery a variety of therapeutic modalities. |
FILED | Tuesday, March 05, 2013 |
APPL NO | 13/785551 |
ART UNIT | 2655 — Digital Audio Data Processing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 2562/028 (20130101) A61B 2562/164 (20130101) A61B 2562/166 (20130101) A61B 2562/0204 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/75 (20130101) H04R 25/554 (20130101) H04R 25/606 (20130101) Original (OR) Class H04R 2225/51 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 09527022 | Baird et al. |
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FUNDED BY |
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APPLICANT(S) | Lance A. Baird (Prospects Heights, Illinois); Timothy A. Brandvold (Arlington Heights, Illinois); Stefan Müller (North Vancouver, Canada) |
ASSIGNEE(S) | UOP LLC (Des Plaines, Illinois) |
INVENTOR(S) | Lance A. Baird (Prospects Heights, Illinois); Timothy A. Brandvold (Arlington Heights, Illinois); Stefan Müller (North Vancouver, Canada) |
ABSTRACT | Methods and apparatus to improve hot gas filtration to reduce the liquid fuel loss caused by prolonged residence time at high temperatures are described. The improvement can be obtained by reducing the residence time at elevated temperature by reducing the temperature of the pyrolysis vapor, by reducing the volume of the pyrolysis vapor at the elevated temperature, by increasing the volumetric flow rate at constant volume of the pyrolysis vapor, or by doing a combination of these. |
FILED | Friday, June 08, 2012 |
APPL NO | 13/492551 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 46/00 (20130101) Original (OR) Class B01D 2273/00 (20130101) Separating Solids From Solids by Sieving, Screening, Sifting or by Using Gas Currents; Separating by Other Dry Methods Applicable to Bulk Material, e.g Loose Articles Fit to be Handled Like Bulk Material B07B 7/00 (20130101) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 53/02 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/84 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/04 (20130101) C10K 1/024 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527029 | Elliott et al. |
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FUNDED BY |
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APPLICANT(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
ASSIGNEE(S) | TDA RESEARCH, INC. (Wheat Ridge, Colorado) |
INVENTOR(S) | Jeannine Elizabeth Elliott (Superior, Colorado); Robert James Copeland (Arvada, Colorado) |
ABSTRACT | A circulating moving bed and process for separating a carbon dioxide from a gas stream is disclosed. The circulating moving bed can include an adsorption reactor and a desorption reactor, and a sorbent that moves through the two reactors. The sorbent can enter the adsorptive reactor and one end and move to an exit point distal to its entry point, while a CO2 feed stream can enter near the distal point and move countercurrently through the sorbent to exit at a position near the entry point of the sorbent. The sorbent can adsorb the CO2 by concentration swing adsorption and adsorptive displacement. The sorbent can then transfer to a regeneration reactor and can move countercurrently against a flow of steam through the regeneration reactor. The sorbent can be regenerated and the carbon dioxide recaptured by desorbing the carbon dioxide from the sorbent using concentration swing desorption and desorptive displacement with steam. |
FILED | Tuesday, July 08, 2014 |
APPL NO | 14/325519 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 53/06 (20130101) Original (OR) Class B01D 2253/104 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2259/402 (20130101) B01D 2259/4009 (20130101) B01D 2259/4065 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101) Y02C 10/06 (20130101) Y02C 10/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527164 | Harley et al. |
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FUNDED BY |
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APPLICANT(S) | SunPower Corporation (San Jose, California) |
ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
INVENTOR(S) | Gabriel Harley (Mountain View, California); Thomas Pass (San Jose, California); Peter John Cousins (Menlo Park, California); John Viatella (San Mateo, California) |
ABSTRACT | A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source. |
FILED | Friday, September 19, 2014 |
APPL NO | 14/491662 |
ART UNIT | 2813 — Semiconductors/Memory |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/40 (20130101) B23K 26/067 (20130101) B23K 26/082 (20151001) B23K 26/0823 (20130101) B23K 26/4075 (20130101) Original (OR) Class B23K 2203/50 (20151001) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/202 (20130101) H01L 31/0682 (20130101) H01L 31/02168 (20130101) H01L 31/022441 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/547 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527741 | Kumar et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Priyank Vijaya Kumar (Cambridge, Massachusetts); Neelkanth M. Bardhan (Cambridge, Massachusetts); Angela Belcher (Lexington, Massachusetts); Jeffrey Grossman (Brookline, Massachusetts) |
ABSTRACT | Embodiments described herein generally relate to compositions comprising a graphene oxide species. In some embodiments, the compositions advantageously have relatively high oxygen content, even after annealing. |
FILED | Monday, May 05, 2014 |
APPL NO | 14/270276 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/043 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527746 | Bohnert et al. |
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FUNDED BY |
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APPLICANT(S) | George Bohnert (Harrisonville, Missouri); James Lula (Lone Jack, Missouri); Daniel E. Bowen, III (Olathe, Kansas) |
ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
INVENTOR(S) | George Bohnert (Harrisonville, Missouri); James Lula (Lone Jack, Missouri); Daniel E. Bowen, III (Olathe, Kansas) |
ABSTRACT | A method of making a carbon binder-reinforced carbon fiber composite is provided using carbonized asphaltenes as the carbon binder. Combinations of carbon fiber and asphaltenes are also provided, along with the resulting composites and articles of manufacture. |
FILED | Tuesday, May 22, 2012 |
APPL NO | 13/477603 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/082 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 7/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 442/2984 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528119 | Sayre et al. |
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FUNDED BY |
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APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Richard T. Sayre (Los Alamos, New Mexico); Sowmya Subramanian (Los Alamos, New Mexico); Edgar Cahoon (Lincoln, Nebraska) |
ABSTRACT | Disclosed herein are transgenic cells expressing a heterologous nucleic acid encoding a prephenate dehydrogenase (PDH) protein, a heterologous nucleic acid encoding a homogentisate solanesyl transferase (HST) protein, a heterologous nucleic acid encoding a deoxyxylulose phosphate synthase (DXS) protein, or a combination of two or more thereof. In particular examples, the disclosed transgenic cells have increased plastoquinone levels. Also disclosed are methods of increasing cell growth rates or production of biomass by cultivating transgenic cells expressing a heterologous nucleic acid encoding a PDH protein, a heterologous nucleic acid encoding an HST protein, a heterologous nucleic acid encoding a DXS protein, or a combination of two or more thereof under conditions sufficient to produce cell growth or biomass. |
FILED | Tuesday, June 17, 2014 |
APPL NO | 14/307180 |
ART UNIT | 1663 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8261 (20130101) Original (OR) Class C12N 15/8269 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528182 | Bluhm et al. |
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FUNDED BY |
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APPLICANT(S) | Martin E. Bluhm (Westfield, New Jersey); Gary S. Silverman (Chadds Ford, Pennsylvania); Roman Y. Korotkov (Boothwyn, Pennsylvania) |
ASSIGNEE(S) | Arkema Inc. (King of Prussia, Pennsylvania) |
INVENTOR(S) | Martin E. Bluhm (Westfield, New Jersey); Gary S. Silverman (Chadds Ford, Pennsylvania); Roman Y. Korotkov (Boothwyn, Pennsylvania) |
ABSTRACT | Complexes of metals and N,O polydentate ligands are useful as precursors in the preparation of doped zinc oxide coatings by chemical vapor deposition. |
FILED | Wednesday, June 09, 2010 |
APPL NO | 13/377858 |
ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/40 (20130101) C23C 16/407 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528197 | Naskar |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee) |
ABSTRACT | Method for the preparation of carbon fiber, which comprises: (i) immersing functionalized polyvinyl precursor fiber into a liquid solution having a boiling point of at least 60° C.; (ii) heating the liquid solution to a first temperature of at least 25° C. at which the functionalized precursor fiber engages in an elimination-addition equilibrium while a tension of at least 0.1 MPa is applied to the fiber; (iii) gradually raising the first temperature to a final temperature that is at least 20° C. above the first temperature and up to the boiling point of the liquid solution for sufficient time to convert the functionalized precursor fiber to a pre-carbonized fiber; and (iv) subjecting the pre-carbonized fiber produced according to step (iii) to high temperature carbonization conditions to produce the final carbon fiber. Articles and devices containing the fibers, including woven and non-woven mats or paper forms of the fibers, are also described. |
FILED | Wednesday, April 10, 2013 |
APPL NO | 13/860188 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) D01F 9/20 (20130101) D01F 9/21 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528465 | Hagen et al. |
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FUNDED BY |
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APPLICANT(S) | Christopher Hagen (Bend, Oregon); Guy Babbitt (Fort Collins, Colorado) |
ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
INVENTOR(S) | Christopher Hagen (Bend, Oregon); Guy Babbitt (Fort Collins, Colorado) |
ABSTRACT | This application concerns systems and methods for compressing natural gas with an internal combustion engine. In a representative embodiment, a method is featured which includes placing a first cylinder of an internal combustion engine in a compressor mode, and compressing a gas within the first cylinder, using the cylinder as a reciprocating compressor. In some embodiments a compression check valve system is used to regulate pressure and flow within cylinders of the engine during a compression process. |
FILED | Wednesday, April 01, 2015 |
APPL NO | 14/676725 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 33/22 (20130101) Controlling Combustion Engines F02D 17/026 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/42 (20130101) Original (OR) Class F02F 2001/244 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 21/0218 (20130101) F02M 21/0224 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/32 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4927 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528701 | Hughes |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | Michael John Hughes (Pittsburgh, Pennsylvania) |
ABSTRACT | A system for tuning a combustor of a gas turbine includes a flow sleeve having an annular main body. The main body includes an upstream end, a downstream end, an inner surface and an outer surface. A cooling channel extends along the inner surface of the main body. The cooling channel extends at least partially between the downstream end and the upstream end of the main body. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/833878 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) Original (OR) Class F23R 3/005 (20130101) F23R 3/46 (20130101) F23R 2900/03043 (20130101) F23R 2900/03044 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528704 | Hughes et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | Michael John Hughes (Pittsburgh, Pennsylvania); Gregory Allen Boardman (West Chester, Ohio); Johnie Franklin McConnaughhay (Greenville, South Carolina); Carlo Antonio Arguinzoni (Greenville, South Carolina) |
ABSTRACT | A system includes a a combustor cap configured to be coupled to a plurality of mixing tubes of a multi-tube fuel nozzle, wherein each mixing tube of the plurality of mixing tubes is configured to mix air and fuel to form an air-fuel mixture. The combustor cap includes multiple nozzles integrated within the combustor cap. Each nozzle of the multiple nozzles is coupled to a respective mixing tube of the multiple mixing tubes. In addition, each nozzle of the multiple nozzles includes a first end and a second end. The first end is coupled to the respective mixing tube of the multiple mixing tubes. The second end defines a non-round outlet for the air-fuel mixture. Each nozzle of the multiple nozzles includes an inner surface having first and second portions, the first portion radially diverges along an axial direction from the first end to the second end, and the second portion radially converges along the axial direction from the first end to the second end. |
FILED | Friday, February 21, 2014 |
APPL NO | 14/186157 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/16 (20130101) F23R 3/283 (20130101) F23R 3/286 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528706 | Montgomery et al. |
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FUNDED BY |
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APPLICANT(S) | Matthew D. Montgomery (Jupiter, Florida); Richard C. Charron (West Palm Beach, Florida); Jose L. Rodriguez (Lake Mary, Florida); Bernhard W. Küsters (Jupiter, Florida); Jay A. Morrison (Titusville, Florida); Alexander R. Beeck (Orlando, Florida) |
ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
INVENTOR(S) | Matthew D. Montgomery (Jupiter, Florida); Richard C. Charron (West Palm Beach, Florida); Jose L. Rodriguez (Lake Mary, Florida); Bernhard W. Küsters (Jupiter, Florida); Jay A. Morrison (Titusville, Florida); Alexander R. Beeck (Orlando, Florida) |
ABSTRACT | A gas turbine engine can-annular combustion arrangement (10), including: an axial compressor (82) operable to rotate in a rotation direction (60); a diffuser (100, 110) configured to receive compressed air (16) from the axial compressor; a plenum (22) configured to receive the compressed air from the diffuser; a plurality of combustor cans (12) each having a combustor inlet (38) in fluid communication with the plenum, wherein each combustor can is tangentially oriented so that a respective combustor inlet is circumferentially offset from a respective combustor outlet in a direction opposite the rotation direction; and an airflow guiding arrangement (80) configured to impart circumferential motion to the compressed air in the plenum in the direction opposite the rotation direction. |
FILED | Friday, December 13, 2013 |
APPL NO | 14/105313 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive-displacement Pumps F04D 29/542 (20130101) F04D 29/545 (20130101) F04D 29/547 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/02 (20130101) F23R 3/04 (20130101) F23R 3/46 (20130101) Original (OR) Class F23R 3/425 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528785 | Klett et al. |
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FUNDED BY |
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APPLICANT(S) | James W. Klett (Knoxville, Tennessee); Michael P. Trammell (Jacksboro, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | James W. Klett (Knoxville, Tennessee); Michael P. Trammell (Jacksboro, Tennessee) |
ABSTRACT | Disclosed are examples of an apparatus for cooling a barrel 12 of a firearm 10 and examples of a cooled barrel assembly 32 for installation into an existing firearm 10. When assembled with the barrel 12, a contact surface 16 of a shell 14 is proximate to, and in thermal communication with, the outer surface of the barrel 18. The shell 14 is formed of commercially available or modified graphite foam. |
FILED | Tuesday, December 07, 2010 |
APPL NO | 13/700147 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 13/12 (20130101) Original (OR) Class F41A 21/44 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529097 | Dolinsky et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Sergei Ivanovich Dolinsky (Clifton Park, New York); Brian David Yanoff (Niskayuna, New York); Renato Guida (Wynantskill, New York); Adrian Ivan (Niskayuna, New York) |
ABSTRACT | A pixelated gamma detector includes a scintillator column assembly having scintillator crystals and optical transparent elements alternating along a longitudinal axis, a collimator assembly having longitudinal walls separated by collimator septum, the collimator septum spaced apart to form collimator channels, the scintillator column assembly positioned adjacent to the collimator assembly so that the respective ones of the scintillator crystal are positioned adjacent to respective ones of the collimator channels, the respective ones of the optical transparent element are positioned adjacent to respective ones of the collimator septum, and a first photosensor and a second photosensor, the first and the second photosensor each connected to an opposing end of the scintillator column assembly. A system and a method for inspecting and/or detecting defects in an interior of an object are also disclosed. |
FILED | Thursday, June 30, 2016 |
APPL NO | 15/198502 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2223/41 (20130101) G01N 2223/053 (20130101) G01N 2223/505 (20130101) G01N 2223/628 (20130101) G01N 2223/646 (20130101) Measurement of Nuclear or X-radiation G01T 1/202 (20130101) Original (OR) Class G01T 1/1644 (20130101) G01T 1/2002 (20130101) G01T 1/2018 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529098 | Stoupin et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Stanislav Stoupin (Willowbrook, Illinois); Yury Shvydko (Lisle, Illinois); John Katsoudas (Chicago, Illinois); Vladimir D. Blank (Moscow, Russian Federation); Sergey A. Terentyev (Moscow, Russian Federation) |
ABSTRACT | An X-ray article and method for analyzing hard X-rays which have interacted with a test system. The X-ray article is operative to diffract or otherwise process X-rays from an input X-ray beam which have interacted with the test system and at the same time provide an electrical circuit adapted to collect photoelectrons emitted from an X-ray optical element of the X-ray article to analyze features of the test system. |
FILED | Monday, September 30, 2013 |
APPL NO | 14/041831 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/26 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529653 | Bose et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Pradip Bose (Yorktown Heights, New York); Chen-Yong Cher (Port Chester, New York); Meeta S. Gupta (Bangalore, India) |
ABSTRACT | Processor register protection management is disclosed. In embodiments, a method of processor register protection management can include determining a sensitive logical register for executable code generated by a compiler, generating an error-correction table identifying the sensitive logical register, and storing the error-correction table in a memory accessible by a processor. The processor can be configured to generate a duplicate register of the sensitive logical register identified by the error-correction table. |
FILED | Thursday, October 09, 2014 |
APPL NO | 14/510350 |
ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 11/20 (20130101) G06F 11/073 (20130101) Original (OR) Class G06F 11/0721 (20130101) G06F 11/0793 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530090 | Nekoogar et al. |
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FUNDED BY |
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APPLICANT(S) | Faranak Nekoogar (San Ramon, California); Farid Dowla (Castro Valley, California); Richard Twogood (San Diego, California); Scott Lefton (Melrose, Massachusetts) |
ASSIGNEE(S) | Dirac Solutions Inc. (Pleasanton, California) |
INVENTOR(S) | Faranak Nekoogar (San Ramon, California); Farid Dowla (Castro Valley, California); Richard Twogood (San Diego, California); Scott Lefton (Melrose, Massachusetts) |
ABSTRACT | A circuit board anti-tamper mechanism comprises a circuit board having a frangible portion, a trigger having a trigger spring, a trigger arming mechanism actuated by the trigger wherein the trigger arming mechanism is initially non-actuated, a force producing mechanism, a latch providing mechanical communication between the trigger arming mechanism and the force producing mechanism, wherein the latch initially retains the force producing mechanism in a refracted position. Arming pressure applied to the trigger sufficient to overcome the trigger spring force will actuate the trigger arming mechanism, causing the anti-tamper mechanism to be armed. Subsequent tampering with the anti-tamper mechanism results in a decrease of pressure on the trigger below the trigger spring force, thereby causing the trigger arming mechanism to actuate the latch, thereby releasing the force producing mechanism to apply force to the frangible portion of the circuit board, thereby breaking the circuit board. |
FILED | Friday, May 15, 2015 |
APPL NO | 14/714204 |
ART UNIT | 2876 — Optics |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/07381 (20130101) G06K 19/07798 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0275 (20130101) H05K 5/0208 (20130101) H05K 5/0221 (20130101) H05K 2201/10098 (20130101) Technical Subjects Covered by Former US Classification Y10T 225/371 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530576 | Coleman et al. |
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FUNDED BY |
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APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
INVENTOR(S) | Jody Rustyn Coleman (Aiken, South Carolina); John Thomas Bobbitt, III (Evans, Georgia) |
ABSTRACT | Provided is a device for remote operation of an electrical disconnect. The device can include a handle clamp configured to be secured to an extending member of the electrical disconnect. The device can further include a case clamp configured to be secured to a rigid portion of the electrical disconnect. The device can further include a cable having an exterior sheath coaxially surrounding an inner cable. The inner cable can be coaxially slidable with respect to the exterior sheath. The inner cable can extend through an opening of the case clamp and be secured to the handle clamp. The device can further include an actuator configured to coaxially slide the inner cable such that the handle clamp is actuated towards the case clamp. |
FILED | Thursday, April 10, 2014 |
APPL NO | 14/249468 |
ART UNIT | 2833 — Electrical Circuits and Systems |
CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 3/02 (20130101) Original (OR) Class H01H 9/20 (20130101) H01H 71/1018 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530873 | Carroll et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Malcolm S. Carroll (Albuquerque, New Mexico); Wayne Witzel (Albuquerque, New Mexico); Noah Tobias Jacobson (Albuquerque, New Mexico); Anand Ganti (Albuquerque, New Mexico); Andrew J. Landahl (Albuquerque, New Mexico); Michael Lilly (Albuquerque, New Mexico); Khoi Thi Nguyen (Albuquerque, New Mexico); Nathaniel Bishop (Albuquerque, New Mexico); Stephen M. Carr (Albuquerque, New Mexico); Ezra Bussmann (Albuquerque, New Mexico); Erik Nielsen (Albuquerque, New Mexico); James Ewers Levy (Albuquerque, New Mexico); Robin J. Blume-Kohout (Albuquerque, New Mexico); Rajib Rahman (West Lafayette, Indiana) |
ABSTRACT | A quantum computing device that includes a plurality of semiconductor adiabatic qubits is described herein. The qubits are programmed with local biases and coupling terms between qubits that represent a problem of interest. The qubits are initialized by way of a tuneable parameter, a local tunnel coupling within each qubit, such that the qubits remain in a ground energy state, and that initial state is represented by the qubits being in a superposition of |0> and |1> states. The parameter is altered over time adiabatically or such that relaxation mechanisms maintain a large fraction of ground state occupation through decreasing the tunnel coupling barrier within each qubit with the appropriate schedule. The final state when tunnel coupling is effectively zero represents the solution state to the problem represented in the |0> and |1> basis, which can be accurately read at each qubit location. |
FILED | Tuesday, October 15, 2013 |
APPL NO | 14/054659 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/66977 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530908 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Liang-Yi Chang (White Plains, New York); Talia S. Gershon (White Plains, New York); Richard A. Haight (Mahopac, New York); Yun Seog Lee (White Plains, New York) |
ABSTRACT | A hybrid vapor phase-solution phase CZT(S,Se) growth technique is provided. In one aspect, a method of forming a kesterite absorber material on a substrate includes the steps of: depositing a layer of a first kesterite material on the substrate using a vapor phase deposition process, wherein the first kesterite material includes Cu, Zn, Sn, and at least one of S and Se; annealing the first kesterite material to crystallize the first kesterite material; and depositing a layer of a second kesterite material on a side of the first kesterite material opposite the substrate using a solution phase deposition process, wherein the second kesterite material includes Cu, Zn, Sn, and at least one of S and Se, wherein the first kesterite material and the second kesterite material form a multi-layer stack of the absorber material on the substrate. A photovoltaic device and method of formation thereof are also provided. |
FILED | Thursday, November 13, 2014 |
APPL NO | 14/540986 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0326 (20130101) Original (OR) Class H01L 31/0749 (20130101) H01L 31/1864 (20130101) H01L 31/022466 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530912 | Putnam et al. |
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FUNDED BY |
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APPLICANT(S) | Morgan C. Putnam (Pasadena, California); Michael D. Kelzenberg (Pasadena, California); Harry A. Atwater (South Pasadena, California); Shannon W. Boettcher (Eugene, Oregon); Nathan S. Lewis (La Canada, California); Joshua M. Spurgeon (Pasadena, California); Daniel B. Turner-Evans (Pasadena, California); Emily L. Warren (Pasadena, California) |
ASSIGNEE(S) | The California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Morgan C. Putnam (Pasadena, California); Michael D. Kelzenberg (Pasadena, California); Harry A. Atwater (South Pasadena, California); Shannon W. Boettcher (Eugene, Oregon); Nathan S. Lewis (La Canada, California); Joshua M. Spurgeon (Pasadena, California); Daniel B. Turner-Evans (Pasadena, California); Emily L. Warren (Pasadena, California) |
ABSTRACT | Three-dimensional patterning methods of a three-dimensional microstructure, such as a semiconductor wire array, are described, in conjunction with etching and/or deposition steps to pattern the three-dimensional microstructure. |
FILED | Tuesday, November 30, 2010 |
APPL NO | 12/956422 |
ART UNIT | 1758 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/056 (20141201) H01L 31/068 (20130101) H01L 31/0547 (20141201) H01L 31/1804 (20130101) H01L 31/022425 (20130101) H01L 31/035281 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/547 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530928 | Weiss et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Shimon Weiss (Los Angeles, California); Marcel Bruchez (Pittsburgh, Pennsylvania); Paul A. Alivisatos (Oakland, California) |
ABSTRACT | A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second energy, and (2) one or more linking agents, having a first portion linked to the one or more semiconductor nanocrystals and a second portion capable of linking to one or more affinity molecules. One or more semiconductor nanocrystal compounds are linked to one or more affinity molecules to form a semiconductor nanocrystal probe capable of bonding with one or more detectable substances in a material being analyzed, and capable of, in response to exposure to a first energy, providing a second energy. Also described are processes for respectively: making the semiconductor nanocrystal compound; making the semiconductor nanocrystal probe; and treating materials with the probe. |
FILED | Wednesday, December 11, 2013 |
APPL NO | 14/103725 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/89 (20130101) C09K 11/565 (20130101) C09K 11/883 (20130101) C09K 11/892 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2563/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) G01N 33/542 (20130101) G01N 33/588 (20130101) G01N 33/54373 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/0062 (20130101) Original (OR) Class H01L 33/0083 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/141111 (20150115) Y10T 436/142222 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530991 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | MO-SCI CORPORATION (Rolla, Missouri); THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
ASSIGNEE(S) | MO-SCI Corporation (Rolla, Missouri); The Curators of the University of Missouri (Columbia, Missouri) |
INVENTOR(S) | Cheol Woon Kim (Rolla, Missouri); Richard K. Brow (Rolla, Missouri) |
ABSTRACT | A sealant for forming a seal between at least two solid oxide fuel cell components wherein the sealant comprises a glass material comprising B2O3 as a principal glass former, BaO, and other components and wherein the glass material is substantially alkali-free and contains less than 30% crystalline material. |
FILED | Tuesday, July 23, 2013 |
APPL NO | 14/346619 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/064 (20130101) C03C 3/066 (20130101) C03C 3/068 (20130101) C03C 8/02 (20130101) C03C 8/04 (20130101) C03C 8/24 (20130101) C03C 2207/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/065 (20130101) Original (OR) Class H01M 8/0206 (20130101) H01M 8/0282 (20130101) H01M 8/0286 (20130101) H01M 2008/1293 (20130101) H01M 2300/0074 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Y02E 60/525 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531002 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | Sharp Laboratories of America, Inc. (Camas, Washington) |
ASSIGNEE(S) | Sharp Laboratories of America, Inc. (Camas, Washington) |
INVENTOR(S) | Yuhao Lu (Vancouver, Washington); Long Wang (Vancouver, Washington); Jong-Jan Lee (Camas, Washington) |
ABSTRACT | A method is provided for cycling power in a transition metal cyanometallate (TMCM) cathode battery. The method provides a battery with a TMCM cathode, an anode, and an electrolyte, where TMCM corresponds to the chemical formula of AXM1NM2M(CN)Y-d(H2O), where “A” is an alkali or alkaline earth metal, and where M1 and M2 are transition metals. The method charges the battery using a first charging current, or greater. In response to the charging current, a plating of “A” metal is formed overlying a plating surface of the anode. In response to discharging the battery, the “A” metal plating is removed from the anode plating surface. In one aspect, in an initial charging of the battery, a permanent solid electrolyte interphase (SEI) layer is formed overlying the anode plating surface. In subsequent charging and discharging cycles, the permanent SEI layer is maintained overlying the anode plating surface. |
FILED | Wednesday, March 25, 2015 |
APPL NO | 14/668788 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Ammonia; Cyanogen; Compounds Thereof C01C 3/12 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 4/136 (20130101) Original (OR) Class H01M 4/0404 (20130101) H01M 4/0452 (20130101) H01M 4/661 (20130101) H01M 4/663 (20130101) H01M 4/667 (20130101) H01M 4/668 (20130101) H01M 4/1397 (20130101) H01M 10/054 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531003 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | Sharp Laboratories of America, Inc. (Camas, Washington) |
ASSIGNEE(S) | Sharp Laboratories of America, Inc. (Camas, Washington) |
INVENTOR(S) | Yuhao Lu (Vancouver, Washington); Sean Andrew Vail (Vancouver, Washington) |
ABSTRACT | A method is provided for synthesizing sodium iron(II)-hexacyanoferrate(II). A Fe(CN)6 material is mixed with the first solution and either an anti-oxidant or a reducing agent. The Fe(CN)6 material may be either ferrocyanide ([Fe(CN)6]4−) or ferricyanide ([Fe(CN)6]3−). As a result, sodium iron(II)-hexacyanoferrate(II) (Na1+XFe[Fe(CN)6]Z. |
FILED | Monday, July 25, 2016 |
APPL NO | 15/218508 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/14 (20130101) H01M 4/049 (20130101) H01M 4/58 (20130101) H01M 4/136 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 4/1397 (20130101) H01M 10/056 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531322 | Okandan et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Murat Okandan (Edgewood, New Mexico); Gregory N. Nielson (Lehi, Utah) |
ABSTRACT | A PV system composed of sub-arrays, each having a group of PV cells that are electrically connected to each other. A power management circuit for each sub-array has a communications interface and serves to connect or disconnect the sub-array to a programmable power grid. The power grid has bus rows and bus columns. A bus management circuit is positioned at a respective junction of a bus column and a bus row and is programmable through its communication interface to connect or disconnect a power path in the grid. As a result, selected sub-arrays are connected by selected power paths to be in parallel so as to produce a low system voltage, and, alternately in series so as to produce a high system voltage that is greater than the low voltage by at least a factor of ten. |
FILED | Tuesday, April 19, 2016 |
APPL NO | 15/133163 |
ART UNIT | 1756 — Electrical Circuits and Systems |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/443 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/042 (20130101) H01L 31/02021 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/383 (20130101) H02J 7/35 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/36 (20141201) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 09526438 | Iskander et al. |
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FUNDED BY |
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APPLICANT(S) | Magdy F. Iskander (Honolulu, Hawaii); Nuri Celik (Honolulu, Hawaii); Ruthsenne Gagarin (Pearl City, Hawaii); Gui Chao Huang (Honolulu, Hawaii); Darcy Alan Bibb (Honolulu, Hawaii) |
ASSIGNEE(S) | University of Hawaii (Honolulu, Hawaii) |
INVENTOR(S) | Magdy F. Iskander (Honolulu, Hawaii); Nuri Celik (Honolulu, Hawaii); Ruthsenne Gagarin (Pearl City, Hawaii); Gui Chao Huang (Honolulu, Hawaii); Darcy Alan Bibb (Honolulu, Hawaii) |
ABSTRACT | A microwave stethoscope measurement method and sensor design employ a microwave transmission sensor and a microwave reception sensor placed on a patient's chest in spaced-apart side-by-side configuration for monitoring patient vital signs, lung water content and other critical measurements. The side-by-side sensors are spaced apart a separation distance of about 1-3 cm in lateral chest orientation. The sensors may be formed with a textile fabric for wearer comfort and to improve contact with the patient's skin. The microwave sensor measurements are digitally processed using a modified short time Fourier Transform (STFT) spectrum windowed-averaged algorithm. Output data extracted from the microwave sensor measurements may be transmitted wirelessly to a mobile device such as a smartphone for remote monitoring of the patient's medical condition. |
FILED | Friday, April 25, 2014 |
APPL NO | 14/261884 |
ART UNIT | 3777 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0205 (20130101) A61B 5/0507 (20130101) Original (OR) Class A61B 5/0816 (20130101) A61B 5/02444 (20130101) A61B 5/4878 (20130101) A61B 5/6804 (20130101) A61B 2562/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526786 | Landry et al. |
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FUNDED BY |
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APPLICANT(S) | Donald W. Landry (New York, New York); James H. Woods (Ann Arbor, Michigan); Roger K. Sunahara (Ann Arbor, Michigan); Diwahar L. Narasimhan (Ann Arbor, Michigan); Joanne MacDonald (New York, New York); Milan N. Stojanovic (Fort Lee, New Jersey); John J. Tesmer (Ann Arbor, Michigan); Remy L. Brim (Farmington Hills, Michigan) |
ASSIGNEE(S) | The Trustee of Columbia University in the City of New York (New York, New York); The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Donald W. Landry (New York, New York); James H. Woods (Ann Arbor, Michigan); Roger K. Sunahara (Ann Arbor, Michigan); Diwahar L. Narasimhan (Ann Arbor, Michigan); Joanne MacDonald (New York, New York); Milan N. Stojanovic (Fort Lee, New Jersey); John J. Tesmer (Ann Arbor, Michigan); Remy L. Brim (Farmington Hills, Michigan) |
ABSTRACT | Provided are compositions comprising a cocaine esterase (CocE) and a compound that thermostabilizes the CocE. Also provided are methods of thermostabilizing a cocaine esterase. Additionally provided are methods of treating a mammal undergoing a cocaine-induced condition. Methods of determining whether a compound is a thermostabilizing agent for a protein are also provided. Uses of the above-described compositions for the treatment of a cocaine-induced condition is additionally provided. Additionally provided is an isolated nucleic acid encoding a CocE polypeptide having the substitutions L169K and G173Q, and the CocE polypeptide encoded by that nucleic acid, and pharmaceutical compositions thereof. Further provided is the use of that composition for the manufacture of a medicament for the treatment of a cocaine-induced condition and for the treatment of a cocaine-induced condition. |
FILED | Tuesday, January 28, 2014 |
APPL NO | 14/166619 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 38/465 (20130101) A61K 38/465 (20130101) A61K 45/06 (20130101) A61K 47/12 (20130101) A61K 47/18 (20130101) A61K 47/22 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/18 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) Enzymes C12Y 301/01084 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/918 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527041 | Wiesner et al. |
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FUNDED BY |
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APPLICANT(S) | Ulrich B. Wiesner (Ithaca, New York); Rachel M. Dorin (Ithaca, New York); Joerg Werner (Ithaca, New York); William A. Phillip (New Haven, Connecticut) |
ASSIGNEE(S) | Cornell University (Ithaca, New York); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Ulrich B. Wiesner (Ithaca, New York); Rachel M. Dorin (Ithaca, New York); Joerg Werner (Ithaca, New York); William A. Phillip (New Haven, Connecticut) |
ABSTRACT | A method for forming an isoporous graded film comprising multiblock copolymers and isoporous graded films. The films have a surface layer and a bulk layer. The surface layer can have at least 1×1014 pores/m2 and a pore size distribution (dmax/dmin)) of less than 3. The bulk layer has an asymmetric structure. The films can be used in filtration applications. |
FILED | Friday, May 04, 2012 |
APPL NO | 14/115218 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 67/0009 (20130101) Original (OR) Class B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/26 (20130101) B01D 71/28 (20130101) B01D 71/44 (20130101) B01D 71/80 (20130101) B01D 2325/04 (20130101) B01D 2325/021 (20130101) B01D 2325/023 (20130101) B01D 2325/48 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 297/04 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2353/00 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527066 | Papish et al. |
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FUNDED BY |
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APPLICANT(S) | Elizabeth T. Papish (Philadelphia, Pennsylvania); Ismael Nieto (Exton, Pennsylvania) |
ASSIGNEE(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
INVENTOR(S) | Elizabeth T. Papish (Philadelphia, Pennsylvania); Ismael Nieto (Exton, Pennsylvania) |
ABSTRACT | The present invention discloses a class of organometallic catalysts for both hydrogenation and water oxidation. The synthesis and the use of these catalysts for hydrogenation, hydrogen production and water oxidation reactions is also disclosed. |
FILED | Monday, August 27, 2012 |
APPL NO | 14/342077 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/122 (20130101) Original (OR) Class B01J 31/181 (20130101) B01J 31/1815 (20130101) B01J 2231/70 (20130101) B01J 2531/821 (20130101) B01J 2531/827 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/06 (20130101) C01B 3/042 (20130101) C01B 13/0207 (20130101) C01B 13/0237 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0033 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/364 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527734 | Groves et al. |
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FUNDED BY |
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APPLICANT(S) | John T. Groves (Princeton, New Jersey); Thomas P. Umile (Ardmore, Pennsylvania) |
ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | John T. Groves (Princeton, New Jersey); Thomas P. Umile (Ardmore, Pennsylvania) |
ABSTRACT | Methods, kits, cartridges and compounds related to generating chlorine dioxide by exposing ClO2− to at least one of a manganese porphyrin catalyst or a manganese porphyrazine catalyst are described. |
FILED | Friday, August 19, 2011 |
APPL NO | 13/818575 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/90 (20130101) A01N 55/02 (20130101) A01N 59/00 (20130101) A01N 59/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2295 (20130101) Non-metallic Elements; Compounds Thereof; C01B 11/024 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/76 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528144 | Bisso et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Paul Bisso (Belmont, Massachusetts); Albert Swiston (Baltimore, Maryland); Jiseok Lee (Melrose, Massachusetts); Patrick S. Doyle (Sudbury, Massachusetts) |
ABSTRACT | Polymer microparticles spatially and spectrally encoded using upconversion nanocrystals (UCN) are described for labeling of articles and tissues. UCN having spectrally distinguishable emission spectra are disposed in different portions of an encoding region of each microparticle. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/214528 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/0026 (20130101) G07D 7/122 (20130101) G07D 7/2033 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/13 (20150115) Y10T 436/143333 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528145 | Bisso et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Paul Bisso (Belmont, Massachusetts); Albert Swiston (Baltimore, Maryland); Jiseok Lee (Melrose, Massachusetts); Patrick S. Doyle (Sudbury, Massachusetts) |
ABSTRACT | Hydrogel microparticles spatially and spectrally encoded using upconverting phosphor nanoparticles are described for use in biochemical testing. In each microparticle, upconversion nanocrystals having spectrally distinguishable emission spectra are disposed in different pardons of an encoding region of the microparticle. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/214594 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/0026 (20130101) G07D 7/122 (20130101) G07D 7/2033 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/13 (20150115) Y10T 436/143333 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528656 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | Arrowhead Center, Inc. (Las Cruces, New Mexico) |
ASSIGNEE(S) | Arrowhead Center, Inc. (Las Cruces, New Mexico) |
INVENTOR(S) | Geoffrey Battle Smith (Las Cruces, New Mexico); David C. Johnson (Las Cruces, New Mexico); Shuguang Deng (Las Cruces, New Mexico); Nagamany Nirmalakhandan (Las Cruces, New Mexico) |
ABSTRACT | A new generation elastomeric biopolymer produced by yeast belonging to the family Saccharomycetaceae, and an isolated yeast belonging to the genus Williopsis that produces and secretes the biopolymer. |
FILED | Tuesday, October 14, 2014 |
APPL NO | 14/514177 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 16/00 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/16 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529035 | Orozco et al. |
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FUNDED BY |
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APPLICANT(S) | Antonio Orozco (Washington, District of Columbia); Vladimir V. Talanov (Ellicott City, Maryland); Alfred Benjamin Cawthorne, III (Franklin, Tennessee); Nicholas Eric Gagliolo (Washington, District of Columbia) |
ASSIGNEE(S) | Neocera, LLC (Beltsville, Maryland) |
INVENTOR(S) | Antonio Orozco (Washington, District of Columbia); Vladimir V. Talanov (Ellicott City, Maryland); Alfred Benjamin Cawthorne, III (Franklin, Tennessee); Nicholas Eric Gagliolo (Washington, District of Columbia) |
ABSTRACT | Non-destructive localization of open defects in electronic devices is performed with a DC SQUID based RF magnetometer capable of sensing coherent magnetic fields up to 200 MHz and higher. RF magnetic fields (or RF current) images are correlated to conductive paths layout of the electronic device, and the open defect is pinpointed at a location of RF current disappearance on the current image. The bandwidth limitations associated with transmission line delays between SQUID circuit and readout electronic, as well as with near-field coupling between different parts of the measurement scheme, are overcome by superimposing the RF flux emanating from device under study on the modulation flux to produce at the SQUID output a binary phase modulated RF voltage, which is processed to lock the static flux, and to control modulation regime by producing an AC bias for the RF flux. RF readout electronics is based on a double lock-in through sequential demodulation of the RF component of the output SQUID voltage at the modulation flux frequency ωm and the RF flux frequency ωRF. |
FILED | Monday, November 14, 2011 |
APPL NO | 14/351396 |
ART UNIT | 2867 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/82 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/08 (20130101) G01R 31/088 (20130101) Original (OR) Class G01R 31/308 (20130101) G01R 31/315 (20130101) G01R 33/0356 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530048 | Bartlett et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (La Jolla, California); The Research Foundation of State University of New York (Amherst, New York) |
ASSIGNEE(S) | The Regents Of The University Of California (Oakland, California); The Research Foundation of State University of New York (Amherst, New York) |
INVENTOR(S) | Marian Stewart Bartlett (San Diego, California); Gwen Littlewort-Ford (Solana, California); Javier Movellan (La Jolla, California); Ian Fasel (Tuscan, Arizona); Mark Frank (Amherst, New York) |
ABSTRACT | An automatic facial action coding system and method can include processing an image to identify a face in the image, to detect and align one or more facial features shown in the image, and to define one or more windows on the image. One or more distributions of pixels and color intensities can be quantified in each of the one or more windows to derive one or more two-dimensional intensity distributions of one or more colors within the window. The one or more two-dimensional intensity distributions can be processed to select image features appearing in the one or more windows and to classify one or more predefined facial actions on the face in the image. A facial action code score that includes a value indicating a relative amount of the predefined facial action occurring in the face in the image can be determined for the face in the image for each of the one or more predefined facial actions. |
FILED | Monday, June 23, 2014 |
APPL NO | 14/311814 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00281 (20130101) G06K 9/00288 (20130101) G06K 9/00315 (20130101) G06K 9/00335 (20130101) Original (OR) Class G06K 9/4652 (20130101) G06K 9/6256 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530906 | Han et al. |
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FUNDED BY |
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APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Sang Eon Han (Albuquerque, New Mexico); Brittany R. Hoard (Albuquerque, New Mexico); Sang M. Han (Albuquerque, New Mexico); Swapnadip Ghosh (Albuquerque, New Mexico) |
ABSTRACT | Provided is a method for fabricating a nanopatterned surface. The method includes forming a mask on a substrate, patterning the substrate to include a plurality of symmetry-breaking surface corrugations, and removing the mask. The mask includes a pattern defined by mask material portions that cover first surface portions of the substrate and a plurality of mask space portions that expose second surface portions of the substrate, wherein the plurality of mask space portions are arranged in a lattice arrangement having a row and column, and the row is not oriented parallel to a [110] direction of the substrate. The patterning the substrate includes anisotropically removing portions of the substrate exposed by the plurality of spaces. |
FILED | Friday, October 17, 2014 |
APPL NO | 15/030039 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/202 (20130101) H01L 31/208 (20130101) H01L 31/0747 (20130101) H01L 31/02363 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530912 | Putnam et al. |
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FUNDED BY |
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APPLICANT(S) | Morgan C. Putnam (Pasadena, California); Michael D. Kelzenberg (Pasadena, California); Harry A. Atwater (South Pasadena, California); Shannon W. Boettcher (Eugene, Oregon); Nathan S. Lewis (La Canada, California); Joshua M. Spurgeon (Pasadena, California); Daniel B. Turner-Evans (Pasadena, California); Emily L. Warren (Pasadena, California) |
ASSIGNEE(S) | The California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Morgan C. Putnam (Pasadena, California); Michael D. Kelzenberg (Pasadena, California); Harry A. Atwater (South Pasadena, California); Shannon W. Boettcher (Eugene, Oregon); Nathan S. Lewis (La Canada, California); Joshua M. Spurgeon (Pasadena, California); Daniel B. Turner-Evans (Pasadena, California); Emily L. Warren (Pasadena, California) |
ABSTRACT | Three-dimensional patterning methods of a three-dimensional microstructure, such as a semiconductor wire array, are described, in conjunction with etching and/or deposition steps to pattern the three-dimensional microstructure. |
FILED | Tuesday, November 30, 2010 |
APPL NO | 12/956422 |
ART UNIT | 1758 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/056 (20141201) H01L 31/068 (20130101) H01L 31/0547 (20141201) H01L 31/1804 (20130101) H01L 31/022425 (20130101) H01L 31/035281 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/547 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09530975 | Jurchescu et al. |
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FUNDED BY |
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APPLICANT(S) | WAKE FOREST UNIVERSITY (Winston-Salem, North Carolina) |
ASSIGNEE(S) | Wake Forest University (Winston-Salem, North Carolina) |
INVENTOR(S) | Oana Diana Jurchescu (Winston-Salem, North Carolina); Peter James Diemer (Mocksville, North Carolina) |
ABSTRACT | In one aspect, organic thin film transistors are described herein. In some embodiments, an organic thin film transistor comprises a source terminal, a drain terminal and a gate terminal; a dielectric layer positioned between the gate terminal and the source and drain terminals; and a vibrationally-assisted drop-cast organic film comprising small molecule semiconductor in electrical communication with the source terminal and drain terminal, wherein the transistor has a carrier mobility (μeff) of at least about 1 cm2/V·s. |
FILED | Tuesday, September 24, 2013 |
APPL NO | 14/430813 |
ART UNIT | 2892 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0001 (20130101) H01L 51/0003 (20130101) H01L 51/0026 (20130101) H01L 51/42 (20130101) H01L 51/0512 (20130101) Original (OR) Class H01L 51/0541 (20130101) H01L 51/0545 (20130101) H01L 51/4253 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531075 | Werner et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Douglas H. Werner (State College, Pennsylvania); Zhihao Jiang (State College, Pennsylvania) |
ABSTRACT | An antenna apparatus can include a transmission medium that is positioned within layers of an antenna apparatus that are positioned adjacent to a first upper layer that is configured to include a signal receiving and transmission element (e.g. an antenna, patch antenna, etc.). The transmission medium can include or otherwise be connected to one or more resonators so that only a signal within a pre-selected band is passable through the transmission band. Any signal in a band outside of the pre-selected band may not be passable through the transmission medium due at least in part to the resonators. In some embodiments, the transmission medium may be part of a stripline or a microstrip. Embodiments of the apparatus may also be configured to block backward radiation emittable from the antenna to help prevent a body of a person near that device from absorbing such radiation. |
FILED | Tuesday, June 23, 2015 |
APPL NO | 14/747350 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/273 (20130101) H01Q 9/045 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531194 | Manohar et al. |
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FUNDED BY |
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APPLICANT(S) | Rajit Manohar (Ithaca, New York); Carlos Otero (Ithaca, New York); Jonathan Tse (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Rajit Manohar (Ithaca, New York); Carlos Otero (Ithaca, New York); Jonathan Tse (Ithaca, New York) |
ABSTRACT | A device including a pipeline having a number of groups of pipeline stages. Each group has at least one pipeline stage, a gated power supply power net or a gated ground power net, the gated power supply power net and the gated ground power net having components that allow gating power supply and ground to that group of pipeline stages. The device also has a number of control components, each control component controlling the gating of power supply or ground. Each group of pipeline stages controls the gating of power supply and ground of a subsequent group of pipeline stages. Each one group of pipeline stages being selected such that a forward propagation delay from a preceding group of pipeline stages to that one group is at least equal to a time required for activating gated power supply or ground in that one group. Methods of implementation are also discussed. |
FILED | Friday, April 29, 2011 |
APPL NO | 13/695358 |
ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 4/00 (20130101) Original (OR) Class Pulse Technique H03K 17/20 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/461 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531497 | Shishkin et al. |
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FUNDED BY |
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APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Boris Shishkin (Philadelphia, Pennsylvania); Danh H. Nguyen (Philadelphia, Pennsylvania); Cem Sahin (Philadelphia, Pennsylvania); Kapil R. Dandekar (Philadelphia, Pennsylvania); Nagarajan Kandasamy (Philadelphia, Pennsylvania); David J. Dorsey (Wilmington, Delaware) |
ABSTRACT | A real-time capable, protocol-aware, reactive jammer using GNU Radio and the USRP N210 software-defined radio (SDR) platform detects in-flight packets of known wireless standards and reacts to jam them—within 80 ns of detecting the signal. A reactive jamming device is achieved using low-cost, readily available hardware. The real-time reactive jamming device includes a real-time signal detector that detects an event in received packets in the wireless network, a reactive jamming device that sends a triggering signal when the event is detected, and a jamming generator responsive to the triggering signal to generate a jamming signal that has a user-defined delay so as to enable jamming of specific locations in received packets in the wireless network. The effects of three types of jamming on WiFi (802.11g) and mobile WiMAX (802.16e) networks are demonstrated and jamming performances are quantified by measuring the network throughput using the iperf software tool. |
FILED | Thursday, May 29, 2014 |
APPL NO | 14/290545 |
ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Secret Communication; Jamming of Communication H04K 3/80 (20130101) Original (OR) Class H04K 2203/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531752 | Gribble et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Steven Gribble (Seattle, Washington); Henry Levy (Seattle, Washington); Alexander Moshchuk (Seattle, Washington); Tanya Bragin (Seattle, Washington) |
ABSTRACT | A system analyzes content accessed at a network site to determine whether it is malicious. The system employs a tool able to identify spyware that is piggy-backed on executable files (such as software downloads) and is able to detect “drive-by download” attacks that install software on the victim's computer when a page is rendered by a browser program. The tool uses a virtual machine (VM) to sandbox and analyze potentially malicious content. By installing and running executable files within a clean VM environment, commercial anti-spyware tools can be employed to determine whether a specific executable contains piggy-backed spyware. By visiting a Web page with an unmodified browser inside a clean VM environment, predefined “triggers,” such as the installation of a new library, or the creation of a new process, can be used to determine whether the page mounts a drive-by download attack. |
FILED | Wednesday, April 22, 2015 |
APPL NO | 14/693170 |
ART UNIT | 2494 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 21/53 (20130101) G06F 21/554 (20130101) G06F 21/566 (20130101) G06F 2009/45587 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/14 (20130101) H04L 63/1416 (20130101) H04L 63/1483 (20130101) Original (OR) Class H04L 63/1491 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09532118 | Vuran et al. |
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FUNDED BY |
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APPLICANT(S) | NUTECH VENTURES (Lincoln, Nebraska) |
ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
INVENTOR(S) | Mehmet Vuran (Lincoln, Nebraska); Xin Dong (Lincoln, Nebraska); David Anthony (Lincoln, Nebraska) |
ABSTRACT | Systems and methods are disclosed for an underground antenna structure for radiating through a dissipative medium, the antenna structure. The antenna structure includes a dielectric substrate, a feeding structure disposed on the substrate, and one or more electrical conductors. The one or more electrical conductors are disposed on the substrate, oriented, and buried within the dissipative medium. The electrical conductors are also adapted to radiate signals at a frequency in a half-space adjacent to the dissipative medium. The adaptation include a beamwidth state for one or more of the electrical conductors based at least in part on the relative permittivity of the dissipative medium. |
FILED | Thursday, July 18, 2013 |
APPL NO | 14/415455 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/24 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/885 (20130101) Antennas, i.e Radio Aerials H01Q 1/04 (20130101) H01Q 1/38 (20130101) H01Q 9/16 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 49/15 (20130101) Selecting H04Q 9/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 09526824 | Ferrari et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas); The Ohio State University Research Foundation (Columbus, Ohio) |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas); The Ohio State University Research Foundation (Columbus, Ohio) |
INVENTOR(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugar Land, Texas); Alessandro Grattoni (Houston, Texas); Daniel Fine (Austin, Texas); Randy Goodall (Austin, Texas); Sharath Hosali (Austin, Texas); Ryan Medema (Pflugerville, Texas); Lee Hudson (Elgin, Texas) |
ABSTRACT | A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device. The inlet and outlet may be in direct fluid communication with the nanochannel. |
FILED | Thursday, May 02, 2013 |
APPL NO | 13/875871 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0097 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/00 (20130101) Original (OR) Class A61M 5/14276 (20130101) A61M 37/00 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) B81B 2203/0338 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00119 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/8593 (20150401) Y10T 156/1064 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527044 | Wachsman et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
INVENTOR(S) | Eric D. Wachsman (Fulton, Maryland); Hee Sung Yoon (College Park, Maryland); Takkeun Oh (Daejeon, South Korea); Jianlin Li (Knoxville, Tennessee) |
ABSTRACT | In one embodiment, a membrane of proton-electron conducting ceramics that is useful for the conversion of a hydrocarbon and steam to hydrogen has a porous support coated with a film of a Perovskite-type oxide. By including the Zr and M in the oxide in place of Ce, the stability can be improved while maintaining sufficient hydrogen flux for efficient generation of hydrogen. In this manner, the conversion can be carried out by performing steam methane reforming (SMR) and/or water-gas shift reactions (WGS) at high temperature, where the conversion of CO to CO2 and H2 is driven by the removal of H2 to give high conversions. |
FILED | Tuesday, September 30, 2014 |
APPL NO | 14/502303 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Separation B01D 67/0046 (20130101) B01D 71/024 (20130101) Original (OR) Class B01D 2323/20 (20130101) B01D 2325/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/02 (20130101) B01J 19/2485 (20130101) B01J 2219/00135 (20130101) B01J 2219/0254 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/02 (20130101) C01B 3/34 (20130101) C01B 3/503 (20130101) C01B 3/505 (20130101) C01B 2203/041 (20130101) C01B 2203/047 (20130101) C01B 2203/048 (20130101) C01B 2203/86 (20130101) C01B 2203/0283 (20130101) C01B 2203/0405 (20130101) C01B 2203/0475 (20130101) C01B 2203/0495 (20130101) C01B 2203/1205 (20130101) C01B 2203/1217 (20130101) C01B 2203/1235 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/48 (20130101) C04B 38/0038 (20130101) C04B 38/0038 (20130101) C04B 41/5027 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/30 (20151101) Technical Subjects Covered by Former US Classification Y10T 428/24997 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527977 | Dong et al. |
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FUNDED BY |
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APPLICANT(S) | ASPEN AEROGELS,INC. (Northborough, Massachusetts) |
ASSIGNEE(S) | ASPEN AEROGELS, INC. (Northborough, Massachusetts) |
INVENTOR(S) | Wenting Dong (Marlborough, Massachusetts); Wendell E. Rhine (Belmont, Massachusetts); Decio Coutinho (Marlborough, Massachusetts) |
ABSTRACT | Disclosed and claimed herein are hybrid aerogels which are compositions of tetraalkoxysilanes and bis-(trialkoxysilyl) imides that exhibit low thermal conductivities and high compressive strengths. Methods for their preparation are also provided. |
FILED | Friday, February 05, 2016 |
APPL NO | 15/016629 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0091 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/106 (20130101) C08G 77/54 (20130101) C08G 2220/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0066 (20130101) C08J 9/0085 (20130101) C08J 9/286 (20130101) Original (OR) Class C08J 2201/0502 (20130101) C08J 2205/026 (20130101) C08J 2379/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/20 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/78 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528192 | Chen |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Bin Chen (Palo Alto, California) |
ABSTRACT | Methods and devices for reducing CO2 to produce hydrocarbons are disclosed. A device comprises a photoanode capable of splitting H2O into electrons, protons, and oxygen; an electrochemical cell cathode comprising an electro-catalyst capable of reducing CO2; H2O in contact with the surface of the photoanode; CO2 in contact with the surface of the cathode; and a proton-conducting medium positioned between the photoanode and the cathode. Electrical charges associated with the protons and the electrons move from the photoanode to the cathode, driven in part by a chemical potential difference sufficient to drive the electrochemical reduction of CO2 at the cathode. A light beam is the sole source of energy used to drive chemical reactions. The photoanode can comprise TiO2 nanowires or nanotubes, and can also include WO3 nanowires or nanotubes, quantum dots of CdS or PbS, and Ag or Au nanostructures. The cathode can comprise a conductive gas diffusion layer with nanostructures of an electro-catalyst such as Cu or Co. |
FILED | Wednesday, July 31, 2013 |
APPL NO | 13/956218 |
ART UNIT | 1756 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/003 (20130101) C25B 3/04 (20130101) C25B 9/18 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531077 | Weller et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas Weller (Lutz, Florida); David Cure (Tampa, Florida); Paul A. Herzig (St. Petersburg, Florida); Felix Miranda (Olmsted Falls, Ohio) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida); Raytheon Company (Waltham, Massachusetts); The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Thomas Weller (Lutz, Florida); David Cure (Tampa, Florida); Paul A. Herzig (St. Petersburg, Florida); Felix Miranda (Olmsted Falls, Ohio) |
ABSTRACT | A flexible microwave antenna having a “fish-scale” ground plane is provided. The approach represents a significant advance in the combined thickness and flexibility that can be achieved, especially when using relatively thick substrates which are important for optimum antenna performance. An increase in gain was observed when bent in a positive radius of curvature and further reduction of back radiation. |
FILED | Monday, April 20, 2015 |
APPL NO | 14/691201 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/16 (20130101) Original (OR) Class H01Q 9/0407 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531303 | Sherrit et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California); CHEVRON U.S.A. INC. (San Ramon, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); CHEVRON U.S.A. INC. (San Ramon, California) |
INVENTOR(S) | Stewart Sherrit (La Crescenta, California); Phillip E. Walkemeyer (Pasadena, California); Jeffrey L. Hall (Pasadena, California); Hyeong Jae Lee (Pasadena, California); Tim Colonius (Sierra Madre, California); Phillipe Tosi (Houston, Texas); Namhyo Kim (Houston, Texas); Kai Sun (Missouri City, Texas); Thomas Gary Corbett (Willis, Texas); Alvaro Jose Arrazola (Houston, Texas) |
ABSTRACT | A flow energy harvesting device having a harvester pipe includes a flow inlet that receives flow from a primary pipe, a flow outlet that returns the flow into the primary pipe, and a flow diverter within the harvester pipe having an inlet section coupled to the flow inlet, a flow constriction section coupled to the inlet section and positioned at a midpoint of the harvester pipe and having a spline shape with a substantially reduced flow opening size at a constriction point along the spline shape, and an outlet section coupled to the constriction section. The harvester pipe may further include a piezoelectric structure extending from the inlet section through the constriction section and point such that the fluid flow past the constriction point results in oscillatory pressure amplitude inducing vibrations in the piezoelectric structure sufficient to cause a direct piezoelectric effect and to generate electrical power for harvesting. |
FILED | Thursday, April 24, 2014 |
APPL NO | 14/261412 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/1136 (20130101) Electric Machines Not Otherwise Provided for H02N 2/185 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 09526247 | Koivunen et al. |
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FUNDED BY |
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APPLICANT(S) | Marrone Bio Innovations, Inc. (Davis, California) |
ASSIGNEE(S) | Marrone Bio Innovations, Inc. (Davis, California) |
INVENTOR(S) | Marja Koivunen (Davis, California); Pamela Marrone (Davis, California) |
ABSTRACT | There is a need for a selective, low-risk herbicide that can be used to control weeds in cereal cultures and turf. The present invention discloses that a bacterial secondary metabolite, thaxtomin and optionally another herbicide is an effective herbicide on broadleaved, sedge and grass weeds. Thaxtomin A and structurally similar compounds can be used as natural herbicides to control the germination and growth of weeds in cereal, turf grass, Timothy grass and pasture grass cultures with no phytotoxicity to these crops. As a natural, non-toxic compound, thaxtomin can be used as a safe alternative for weed control in both conventional and organic farming and gardening systems. |
FILED | Thursday, July 31, 2014 |
APPL NO | 14/447617 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/18 (20130101) A01N 37/22 (20130101) A01N 37/22 (20130101) A01N 37/34 (20130101) A01N 37/40 (20130101) A01N 39/02 (20130101) A01N 39/04 (20130101) A01N 41/10 (20130101) A01N 43/36 (20130101) A01N 43/54 (20130101) A01N 43/54 (20130101) A01N 43/60 (20130101) Original (OR) Class A01N 43/60 (20130101) A01N 43/60 (20130101) A01N 43/76 (20130101) A01N 43/80 (20130101) A01N 43/80 (20130101) A01N 43/90 (20130101) A01N 43/90 (20130101) A01N 47/12 (20130101) A01N 57/20 (20130101) A01N 57/20 (20130101) A01N 65/00 (20130101) A01N 65/40 (20130101) A01N 65/44 (20130101) A01N 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526748 | Centanni et al. |
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FUNDED BY |
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APPLICANT(S) | STRATATECH CORPORATION (Madison, Wisconsin) |
ASSIGNEE(S) | STRATATECH CORPORATION (Madison, Wisconsin) |
INVENTOR(S) | John M. Centanni (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin) |
ABSTRACT | The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides. |
FILED | Friday, July 18, 2014 |
APPL NO | 14/335534 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/36 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 38/1825 (20130101) A61K 2035/122 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/60 (20130101) A61L 27/3813 (20130101) A61L 27/3895 (20130101) A61L 2300/252 (20130101) A61L 2300/404 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0629 (20130101) C12N 5/0698 (20130101) C12N 15/63 (20130101) C12N 15/79 (20130101) C12N 2501/117 (20130101) C12N 2501/998 (20130101) C12N 2502/094 (20130101) C12N 2502/1323 (20130101) C12N 2510/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526946 | Zets et al. |
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FUNDED BY |
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APPLICANT(S) | Gary Zets (Casselberry, Florida); Bruce Mortimer (Casselberry, Florida) |
ASSIGNEE(S) | |
INVENTOR(S) | Gary Zets (Casselberry, Florida); Bruce Mortimer (Casselberry, Florida) |
ABSTRACT | A system and method for providing therapy and assessment utilizing vibrotactile feedback is disclosed and claimed. Such treatment is useful for the treatment of disequilibrium and balance disorders. The system and method uses sensors such as force plates, inertial sensors, and three dimensional cameras to provide a subject with vibrotactile feedback in response to an attempt by the subject to perform predetermined motions. Predetermined motions are motions such as stand, sit-to-stand, reach, bend, functional gait, functional gait plus headshake, and other functional tasks. Vibrotactile stimulation may be applied during the subject's performance of a functional gait task as a disruptive input. Variance and rate of change of variance between measured and expected parameters are determined and used as a tool for assessment, and may also be used for providing real-time vibrotactile training. Such assessment and therapy is useful in the treatment of Traumatic Brain Injury (TBI). |
FILED | Friday, November 18, 2011 |
APPL NO | 13/300333 |
ART UNIT | 3764 — Organic Chemistry |
CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 24/00 (20130101) Original (OR) Class A63B 24/0003 (20130101) A63B 24/0006 (20130101) A63B 24/0021 (20130101) A63B 2024/0009 (20130101) A63B 2024/0012 (20130101) A63B 2024/0015 (20130101) A63B 2024/0025 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 21/00 (20130101) G09B 21/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09527722 | Rastegar |
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FUNDED BY |
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APPLICANT(S) | Jahangir S Rastegar (Stony Brook, New York) |
ASSIGNEE(S) | OMNITEK PARTNERS LLC (Ronkonkoma, New York) |
INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York) |
ABSTRACT | A MEMS sensor including: a base structure; at least one component formed from the base structure which moves relative to the base structure; and one or more locking mechanisms for locking the at least one component in a predetermined stationary position in response to external stimuli exceeding predetermined thresholds in at least first and second directions, where the first direction is different from the second direction. |
FILED | Tuesday, June 11, 2013 |
APPL NO | 13/915602 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0016 (20130101) Original (OR) Class Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0195 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5755 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) G01P 15/125 (20130101) G01P 15/0891 (20130101) G01P 2015/0814 (20130101) G01P 2015/0837 (20130101) G01P 2015/0871 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529003 | Kleinfeld et al. |
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FUNDED BY |
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APPLICANT(S) | Alan Marc Kleinfeld (La Jolla, California); Andrew Henry Huber (Encinitas, California); James Patrick Kampf (San Diego, California); Thomas Kwan (San Diego, California); Baolong Zhu (San Diego, California) |
ASSIGNEE(S) | Alan Marc Kleinfeld (La Jolla, California) |
INVENTOR(S) | Alan Marc Kleinfeld (La Jolla, California); Andrew Henry Huber (Encinitas, California); James Patrick Kampf (San Diego, California); Thomas Kwan (San Diego, California); Baolong Zhu (San Diego, California) |
ABSTRACT | Identification and use of proteins fluorescently labeled and that undergo a change in fluorescence index upon binding bilirubin are described. Probes are disclosed which are labeled at a cysteine or lysine residue and also probes labeled at both cysteine and lysine with two different fluorophores. These probes are useful for determination of unbound bilirubin levels in a fluid sample. |
FILED | Friday, August 24, 2012 |
APPL NO | 14/238144 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/47 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/92 (20130101) G01N 33/533 (20130101) G01N 33/582 (20130101) G01N 33/728 (20130101) Original (OR) Class G01N 2800/52 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/146666 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09529035 | Orozco et al. |
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FUNDED BY |
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APPLICANT(S) | Antonio Orozco (Washington, District of Columbia); Vladimir V. Talanov (Ellicott City, Maryland); Alfred Benjamin Cawthorne, III (Franklin, Tennessee); Nicholas Eric Gagliolo (Washington, District of Columbia) |
ASSIGNEE(S) | Neocera, LLC (Beltsville, Maryland) |
INVENTOR(S) | Antonio Orozco (Washington, District of Columbia); Vladimir V. Talanov (Ellicott City, Maryland); Alfred Benjamin Cawthorne, III (Franklin, Tennessee); Nicholas Eric Gagliolo (Washington, District of Columbia) |
ABSTRACT | Non-destructive localization of open defects in electronic devices is performed with a DC SQUID based RF magnetometer capable of sensing coherent magnetic fields up to 200 MHz and higher. RF magnetic fields (or RF current) images are correlated to conductive paths layout of the electronic device, and the open defect is pinpointed at a location of RF current disappearance on the current image. The bandwidth limitations associated with transmission line delays between SQUID circuit and readout electronic, as well as with near-field coupling between different parts of the measurement scheme, are overcome by superimposing the RF flux emanating from device under study on the modulation flux to produce at the SQUID output a binary phase modulated RF voltage, which is processed to lock the static flux, and to control modulation regime by producing an AC bias for the RF flux. RF readout electronics is based on a double lock-in through sequential demodulation of the RF component of the output SQUID voltage at the modulation flux frequency ωm and the RF flux frequency ωRF. |
FILED | Monday, November 14, 2011 |
APPL NO | 14/351396 |
ART UNIT | 2867 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/82 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/08 (20130101) G01R 31/088 (20130101) Original (OR) Class G01R 31/308 (20130101) G01R 31/315 (20130101) G01R 33/0356 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 09526240 | Abbas et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); Alma Mater Studiorum Università di Bologna (Bologna, Italy) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); Alma Mater Studiorum-Universita di Bologna (Bologna, Italy) |
INVENTOR(S) | Hamed K Abbas (Greenville, Mississippi); Cesare Accinelli (Bologna, Italy) |
ABSTRACT | A sprayable liquid biodegradable formulation comprising biocontrol microorganisms imbedded in a dispersed starch-based bioplastic is effective for delivering biocontrol microorganisms and bioactive compounds to soil, crops and seeds and facilitating positioning of biocontrol agents in close proximity to target pests. After application with conventional spray equipment, water evaporates rapidly and the dispersed bioplastic formula remains, serving as a prolonged growth substrate for the biocontrol microorganisms. Application of the bioplastic dispersion formulation comprising Beauveria bassiana significantly reduced damages caused by the European Corn Borer in corn and the Tarnished Plant Bug in cotton. Applying a formulation of spores of a non-aflatoxigenic A. flavus isolate resulted in a 97% reduction of aflatoxin contamination of corn. The bioplastic dispersion formulation is effective in delivering crystal Bacillus thuringiens endotoxins to European Corn Borer larvae, causing 72% mortality. The sprayable bioplastic formulation protects seeds from soil-borne pathogens, thereby reducing damping-off in tomato plants by up to 85%. |
FILED | Tuesday, May 13, 2014 |
APPL NO | 14/276224 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) Original (OR) Class A01N 25/10 (20130101) A01N 25/10 (20130101) A01N 43/16 (20130101) A01N 63/02 (20130101) A01N 63/02 (20130101) A01N 63/04 (20130101) A01N 63/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09526247 | Koivunen et al. |
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FUNDED BY |
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APPLICANT(S) | Marrone Bio Innovations, Inc. (Davis, California) |
ASSIGNEE(S) | Marrone Bio Innovations, Inc. (Davis, California) |
INVENTOR(S) | Marja Koivunen (Davis, California); Pamela Marrone (Davis, California) |
ABSTRACT | There is a need for a selective, low-risk herbicide that can be used to control weeds in cereal cultures and turf. The present invention discloses that a bacterial secondary metabolite, thaxtomin and optionally another herbicide is an effective herbicide on broadleaved, sedge and grass weeds. Thaxtomin A and structurally similar compounds can be used as natural herbicides to control the germination and growth of weeds in cereal, turf grass, Timothy grass and pasture grass cultures with no phytotoxicity to these crops. As a natural, non-toxic compound, thaxtomin can be used as a safe alternative for weed control in both conventional and organic farming and gardening systems. |
FILED | Thursday, July 31, 2014 |
APPL NO | 14/447617 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/18 (20130101) A01N 37/22 (20130101) A01N 37/22 (20130101) A01N 37/34 (20130101) A01N 37/40 (20130101) A01N 39/02 (20130101) A01N 39/04 (20130101) A01N 41/10 (20130101) A01N 43/36 (20130101) A01N 43/54 (20130101) A01N 43/54 (20130101) A01N 43/60 (20130101) Original (OR) Class A01N 43/60 (20130101) A01N 43/60 (20130101) A01N 43/76 (20130101) A01N 43/80 (20130101) A01N 43/80 (20130101) A01N 43/90 (20130101) A01N 43/90 (20130101) A01N 47/12 (20130101) A01N 57/20 (20130101) A01N 57/20 (20130101) A01N 65/00 (20130101) A01N 65/40 (20130101) A01N 65/44 (20130101) A01N 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528094 | Borca et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); The University of Connecticut (Storrs, Connecticut) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); The University of Connecticut (Storrs, Connecticut) |
INVENTOR(S) | Manuel V. Borca (Westbrook, Connecticut); Lauren G. Holinka-Patterson (Deep River, Connecticut); Vivian K. O'Donnell (Old Saybrook, Connecticut); Guillermo S. Risatti (Westbrook, Connecticut); Douglas Gladu (Guilford, Connecticut) |
ABSTRACT | African swine fever virus (ASFV) is the etiological agent of a contagious and often lethal viral disease of domestic pigs. Control of ASF has been hampered by the unavailability of vaccines. Experimental vaccines have been derived from naturally occurring, cell culture-adapted, or genetically modified live attenuated ASFVs; however, these vaccines are only successful when protecting against homologous viruses. Among viral genes reported to be involved in virulence are components of the multi gene family (MGF). Here we report the construction of a recombinant ΔMGF virus derived from the highly virulent ASFV Georgia 2007 (ASFV-G) isolate. In vivo, ASFV-G ΔMGF administered intramuscularly (IM) to swine at either 102 or 104 HAD50 are completely attenuated; the inoculated animals are completely asymptomatic. Animals infected with 102 or 104 HAD50 of ASFV-G ΔMGF are protected against the presentation of clinical disease when challenged at 28 days post infection with the virulent parental strain Georgia 2007. |
FILED | Monday, November 10, 2014 |
APPL NO | 14/537248 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2710/12034 (20130101) C12N 2710/12062 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528115 | Weller et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Washington State University Research Foundation (Pullman, Washington) |
ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia); Washington State University (Pullman, Washington) |
INVENTOR(S) | David M Weller (Pullman, Washington); Linda S Thomashow (Pullman, Washington); Dmitri V Mavrodi (Hattiesburg, Mississippi); Mingming Yang (Xianyang, China PRC); Jibin Zhang (Wuhan, China PRC) |
ABSTRACT | In exemplary embodiments, the invention provides Pseudomonas fluorescens 2-79 strains having pyrrolnitrin biosynthetic genes for biocontrol of soilborne diseases. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/208543 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/78 (20130101) Original (OR) Class C12N 2510/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09528124 | Fahrenkrug et al. |
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FUNDED BY |
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APPLICANT(S) | Recombinetics, Inc. (Saint Paul, Minnesota) |
ASSIGNEE(S) | Recombinetics, Inc. (Saint Paul, Minnesota) |
INVENTOR(S) | Scott C. Fahrenkrug (Minneapolis, Minnesota); Daniel F. Carlson (Woodbury, Minnesota) |
ABSTRACT | Methods, uses, and animals for introgression of alleles between animals, including SNPs. One embodiment involves introducing a targeted targeting endonuclease system and a HDR template into a cell with a mismatch in the binding of the targeting endonuclease and the targeted site. |
FILED | Monday, April 28, 2014 |
APPL NO | 14/263446 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Peptides C07K 14/47 (20130101) C07K 14/715 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 15/8509 (20130101) C12N 15/8771 (20130101) C12N 15/8778 (20130101) C12N 2750/14143 (20130101) C12N 2800/30 (20130101) C12N 2800/90 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 09530606 | McClelland et al. |
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FUNDED BY |
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APPLICANT(S) | NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
INVENTOR(S) | Jabez McClelland (Bethesda, Maryland); Truman Wilson (Gaithersburg, Maryland) |
ABSTRACT | An articles includes: an ion source configured to provide a first ion beam that has a first brightness; and a cooler configured to receive the first ion beam and to produce a second ion beam from the first ion beam, the second ion beam including a second brightness that is greater than the first brightness. A process for cooling includes receiving a first ion beam that includes a first brightness in a cooler, and the cooler includes a first mirror and a second mirror disposed opposingly to the first mirror; receiving a first laser beam in the cooler; receiving a second laser beam in the cooler; transmitting the first laser beam and the second laser beam through the first ion beam to decrease an emittance of the first ion beam; reflecting the first laser beam from the first mirror and the second laser beam from the second mirror; and transmitting, after being reflected, the first laser beam and the second laser beam through the first ion beam to cool the first ion beam and to decrease the emittance of the first ion beam to produce a second ion beam that includes a second brightness that is greater than the first brightness. |
FILED | Tuesday, March 24, 2015 |
APPL NO | 14/666871 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 27/022 (20130101) Original (OR) Class H01J 37/04 (20130101) H01J 37/08 (20130101) H01J 37/22 (20130101) H01J 2237/26 (20130101) H01J 2237/30 (20130101) H01J 2237/047 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 09527207 | Low et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas P. Low (Belmont, California); Pablo E. Garcia (Menlo Park, California); Bruce H. Knoth (San Carlos, California); Cregg Cowan (Mountain View, California); Bryan Chavez (Palo Alto, California) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Thomas P. Low (Belmont, California); Pablo E. Garcia (Menlo Park, California); Bruce H. Knoth (San Carlos, California); Cregg Cowan (Mountain View, California); Bryan Chavez (Palo Alto, California) |
ABSTRACT | A robotic manipulator has a body and a stereoscopic video system movably coupled to the body. The stereoscopic vision system produces a stereoscopic video of an environment of the robotic manipulator. The robotic manipulator also includes two independently remotely controlled arms coupled to opposite sides of the body. Each arm moves in proprioceptive alignment with the stereoscopic video produced by the stereoscopic video system in response to commands received from a remote control station based on movements performed by an operator at the remote control station. |
FILED | Wednesday, March 21, 2012 |
APPL NO | 14/005075 |
ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) Original (OR) Class B25J 9/0087 (20130101) B25J 9/161 (20130101) B25J 9/1689 (20130101) B25J 13/025 (20130101) B25J 19/023 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 09529001 | Van de Water et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Judy Van de Water (Capay, California); Daniel Braunschweig (Davis, California) |
ABSTRACT | The present invention provides diagnostic methods for determining the risk of developing an autism spectrum disorder (ASD) in a fetus or child by detecting in a biological sample from the mother antibodies that bind to one or more biomarkers selected from the group consisting of lactate dehydrogenase (LDH), guanine deaminase (GDA), collapsin response mediator protein 1 (CRMP1), stress-induced phosphoprotein 1 (STIP1), alpha subunit of the barbed-end actin binding protein Cap Z (CAPZA2), Y Box Binding Protein 1 (YBX1), eukaryotic translation and elongation factor 1A1 (EEF1A1), microtubule-associated protein Tau (MAPT), dihydropyrimidinase-like protein 2 (DPYSL2), dynamin 1-like protein (DNM1L), radixin (RDX), moesin (MSN), and ezrin (EZR). The invention further provides methods of preventing or reducing the risk of a fetus or child developing an ASD by administering to the mother an agent that blocks the binding of maternal antibodies to the one or more fetal biomarkers listed above or by removing from the mother antibodies that bind to the one or more fetal biomarkers. |
FILED | Wednesday, January 30, 2013 |
APPL NO | 13/754846 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 2800/28 (20130101) G01N 2800/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 09526880 | So et al. |
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FUNDED BY |
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APPLICANT(S) | ViaCyte, Inc. (San Diego, California) |
ASSIGNEE(S) | VIACYTE, INC. (San Diego, California) |
INVENTOR(S) | Vincent So (San Diego, California); Laura Martinson (San Diego, California); Chad Green (San Diego, California); Michael Scott (San Diego, California); Mario Zamarripa (San Diego, California) |
ABSTRACT | Disclosed herein are implantable 3-dimensional large capacity device assemblies, specifically, large capacity device assemblies for encapsulating pancreatic progenitor cells for treatment of diabetes. |
FILED | Friday, March 07, 2014 |
APPL NO | 14/201630 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) Original (OR) Class A61M 2202/09 (20130101) A61M 2205/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
US 09530104 | Laptev et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Nikolay Laptev (Ventura, California); Tsai-Ching Lu (Wynnewood, Pennsylvania) |
ABSTRACT | Described is a system for assessing the quality of machine learning algorithms over massive time series. A set of random blocks of a time series data sample of size n is selected in parallel. Then, r resamples are generated, in parallel, by applying a bootstrapping method to each block in the set of random blocks to obtain a resample of size n, where r is not fixed. Errors are estimated on the r resamples, and a final accuracy estimate is produced by averaging the errors estimated on the r resamples. |
FILED | Friday, February 07, 2014 |
APPL NO | 14/175899 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 09528817 | Fang-Yen et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Christopher Fang-Yen (Philadelphia, Pennsylvania); Gabriel Popescu (Champaign, Illinois); Changhuei Yang (Pasadena, California); Adam Wax (Chapel Hill, North Carolina); Ramachandra Dasari (Shererville, Indiana); Michael Feld (Jamaica Plain, Massachusetts) |
ABSTRACT | Preferred embodiments of the present invention are directed to systems for phase measurement of biological materials which can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at the sub-micron level which can include, without limitation, imaging origins of dysplasia, cellular communication, neuronal transmission and implementation of the genetic code. The structure and dynamics of sub-cellular constituents cannot be currently studied in their native state using the existing methods and technologies including, for example, x-ray and neutron scattering. |
FILED | Friday, December 14, 2012 |
APPL NO | 13/715475 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1455 (20130101) A61B 5/7232 (20130101) A61B 5/14532 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0209 (20130101) G01B 9/02002 (20130101) G01B 9/02007 (20130101) G01B 9/02011 (20130101) G01B 9/02057 (20130101) G01B 9/02063 (20130101) G01B 9/02067 (20130101) G01B 9/02069 (20130101) G01B 9/02071 (20130101) G01B 9/02072 (20130401) G01B 9/02078 (20130101) G01B 9/02083 (20130101) G01B 9/02091 (20130101) Original (OR) Class G01B 2290/45 (20130101) G01B 2290/60 (20130101) G01B 2290/70 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/45 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09531050 | Kroening et al. |
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FUNDED BY |
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APPLICANT(S) | Honeywell International Inc. (Morristown, New Jersey) |
ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
INVENTOR(S) | Adam M. Kroening (Atlanta, Georgia); Lance Covert (Montgomery, Alabama) |
ABSTRACT | A circulator for a waveguide is provided. The circulator comprises a waveguide housing including a central cavity, and a ferrite element disposed in the central cavity of the waveguide housing, with the ferrite element including a first surface and an opposing second surface. The circulator also comprises a pair of asymmetric dielectric spacers including a first dielectric spacer located on the first surface of the ferrite element, and a second dielectric spacer located on the second surface of the ferrite element. |
FILED | Tuesday, August 18, 2015 |
APPL NO | 14/829183 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/38 (20130101) H01P 1/39 (20130101) H01P 1/383 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 27, 2016.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2016/fedinvent-patents-20161227.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page