FedInvent™ Patents
Patent Details for Tuesday, March 28, 2017
This page was updated on Monday, March 27, 2023 at 05:11 AM GMT
Department of Health and Human Services (HHS)
| US 09603522 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kendall H. Lee (Rochester, Minnesota); Kevin E. Bennet (Rochester, Minnesota); Charles D. Blaha (Germantown, Tennessee) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); The University of Memphis Research Foundation (Memphis, Tennessee) |
| INVENTOR(S) | Kendall H. Lee (Rochester, Minnesota); Kevin E. Bennet (Rochester, Minnesota); Charles D. Blaha (Germantown, Tennessee) |
| ABSTRACT | This document relates to methods and materials involved in detecting neurochemical signals, electrophysiological signals, ions, or combinations thereof with brain tissue. For example, methods and materials for using probes to detect neurochemical signals (e.g., neurotransmitter concentrations), electrical signals, or combinations thereof during deep brain stimulation are provided. |
| FILED | Thursday, August 26, 2010 |
| APPL NO | 13/392387 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) Original (OR) Class A61B 5/4064 (20130101) A61B 5/4082 (20130101) A61B 5/6814 (20130101) A61B 2562/02 (20130101) A61B 2562/043 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/08 (20130101) A61N 1/0531 (20130101) A61N 1/0534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603546 | Horkay et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ferenc Horkay (Rockville, Maryland); Carlo Pierpaoli (Rockville, Maryland); Peter J. Basser (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Ferenc Horkay (Rockville, Maryland); Carlo Pierpaoli (Rockville, Maryland); Peter J. Basser (Washington, District of Columbia) |
| ABSTRACT | A phantom calibration body (12) for calibrating diffusion MRI device (16) that mimics a material such as a mammalian tissue is disclosed. The phantom calibration body (12) includes a homogeneous aqueous solution (30) that contains a mixture of low molecular-weight and high molecular-weight polymers housed in a container (14) that is placed in the diffusion MRI device (16) for obtaining one or more diffusion MRI images of the phantom calibration body (12). A measure of diffusivity is calculated for each of the one or more diffusion MRI images in order to calibrate the diffusion MRI device. Methods of using the phantom calibration body (12) to calibrate diffusion MRI device (16) are also disclosed. |
| FILED | Tuesday, January 26, 2010 |
| APPL NO | 13/146058 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/415 (20130101) A61B 5/418 (20130101) A61B 2560/0228 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603567 | Jeraj et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Robert Jeraj (Madison, Wisconsin); Glenn Liu (Waunakee, Wisconsin) |
| ABSTRACT | A sensitive method of assessing treatment using molecular and anatomical imaging scans provides automatic tumor identification and quantification within anatomical zones based on treatment criteria. Absolute or comparative measures of tumors in pre- and/or post-scans are thereby isolated from other tissue to accentuate the progress of the treatment when multiple scattered disease lesions are present. |
| FILED | Monday, October 19, 2015 |
| APPL NO | 14/886835 |
| ART UNIT | 3768 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/055 (20130101) A61B 5/742 (20130101) A61B 5/4848 (20130101) Original (OR) Class A61B 5/7275 (20130101) A61B 6/12 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/461 (20130101) A61B 6/469 (20130101) A61B 6/505 (20130101) A61B 8/48 (20130101) A61B 8/5223 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0083 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/20036 (20130101) G06T 2207/20148 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603674 | Shivkumar |
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| FUNDED BY |
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| APPLICANT(S) | Kalyanam Shivkumar (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kalyanam Shivkumar (Los Angeles, California) |
| ABSTRACT | Devices and methods are disclosed for preventing injury to a target tissue in proximity to the heart. The methods may include the use a device to externally manipulate the heart to move a portion of the heart away from the target tissue. The methods may also include applying therapy to the heart with the device. |
| FILED | Thursday, May 28, 2009 |
| APPL NO | 12/474151 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/16 (20130101) A61B 90/04 (20160201) Original (OR) Class A61B 2018/00023 (20130101) A61B 2090/0418 (20160201) A61B 2090/0481 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603724 | Geyer et al. |
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| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hartmut Geyer (Pittsburgh, Pennsylvania); Ruta P. Desai (Pittsburgh, Pennsylvania) |
| ABSTRACT | Local swing leg control was developed that takes advantage of segment interactions to achieve robust leg placement under large disturbances while generating trajectories and joint torque patterns similar to those observed in human walking and running. The results suggest the identified control as a powerful alternative to existing swing leg controls in humanoid and rehabilitation robotics. Alternatively, a detailed neuromuscular model of the human swing leg was developed to embody the control with local muscle reflexes. The resulting reflex control robustly places the swing leg into a wide range of landing points observed in human walking and running, and it generates similar patterns of joint torques and muscle activations. The results suggest an alternative to existing swing leg controls in humanoid and rehabilitation robotics which does not require central processing. |
| FILED | Wednesday, August 27, 2014 |
| APPL NO | 14/470277 |
| ART UNIT | 3738 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/64 (20130101) A61F 2/68 (20130101) A61F 2/605 (20130101) Original (OR) Class A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/762 (20130101) A61F 2002/6827 (20130101) A61F 2002/7625 (20130101) A61F 2002/7645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09603800 — Methods of treating inflammatory and autoimmune diseases and disorders using nanolipogels
| US 09603800 | Fahmy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Michael Look (Seattle, Washington); Joseph Craft (Hamden, Connecticut) |
| ABSTRACT | Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, an absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant. |
| FILED | Friday, April 12, 2013 |
| APPL NO | 14/394147 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 9/1273 (20130101) Original (OR) Class A61K 9/1277 (20130101) A61K 31/343 (20130101) A61K 38/1841 (20130101) A61K 38/2013 (20130101) A61K 47/24 (20130101) A61K 47/40 (20130101) A61K 47/48176 (20130101) A61K 47/48969 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603818 | Perrine et al. |
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| FUNDED BY |
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| APPLICANT(S) | Susan Park Perrine (Weston, Massachusetts); Douglas V. Faller (Weston, Massachusetts) |
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| INVENTOR(S) | Susan Park Perrine (Weston, Massachusetts); Douglas V. Faller (Weston, Massachusetts) |
| ABSTRACT | The present intervention generally relates to compositions comprising S-isomer of alpha-methyl-hydrocinnamic acid for the treatment and/or prevention of blood disorders and blood deficiencies, as well as methods for treating blood disorders and/or blood deficiency in a subject by administering a composition comprising S-isomer of alpha-methyl-hydrocinnamic acid to the subject to ameliorate at least one symptom associated with the blood disorder. Another aspect relates to administration of an S-isomer of alpha-methyl-hydrocinnamic acid stimulate multi-lineage hematopoietic cell production in a subject, for example, increasing the numbers of circulating neutrophils, erythrocytes and platelets. Accordingly, one aspect of the present invention relates to administration of S-isomer of alpha-methyl-hydrocinnamic acid, e.g., by oral administration to a subject for the treatment of blood disorders, for example but not limited to, hemaglobinapathy, thalassemia and aplastic anemia. In some embodiments, the oral pharmaceutical formulation comprising an S-isomer of α-methyl-hydrocinnamic acid can be used to increase red blood cell proliferation, or increase the proliferation of hemoglobin-expressing cells in a subject in need thereof, e.g., a subject having a blood deficiency such as a subject undergone chemotherapy or radiation exposure or radiation therapy. In some embodiments, a formulation comprising an S-isomer of alpha-methyl-hydrocinnamic acid (ST7S) can be used to simulate myelopiesis or erythropoiesis in a subject in need thereof. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/868638 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0053 (20130101) A61K 9/0095 (20130101) A61K 31/16 (20130101) A61K 31/24 (20130101) A61K 31/165 (20130101) A61K 31/192 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603820 | Silverman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); Hadasit Medical Research Services and Development Ltd. (Jerusalem, Israel) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Yaron Ilan (Kfar Tavor, Israel) |
| ABSTRACT | Therapeutic methods relating to the use of GABA-AT inhibitor compounds for the treatment of hepatocellular carcinoma. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 14/936153 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/196 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603829 | Ross et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | David Ross (Niwot, Colorado); David Siegal (Denver, Colorado); Christopher J. Moody (Leicestershire, United Kingdom); Russell Richard Anthony Kitson (Leicestershire, United Kingdom) |
| ABSTRACT | The invention provides 19-substituted geldanamycin derivatives, and pharmaceutically acceptable salts thereof that are potent Hsp90 binding agents useful for the treatment of, and/or the amelioration of symptoms of, cancer or neurodegenerative disorders. |
| FILED | Wednesday, November 14, 2012 |
| APPL NO | 14/357230 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) Original (OR) Class A61K 31/395 (20130101) A61K 31/704 (20130101) A61K 31/4427 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 225/06 (20130101) C07D 401/04 (20130101) C07D 405/04 (20130101) C07D 409/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603839 | Pearlman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Eric Pearlman (Lakeline, Ohio); Sixto M. Leal, Jr. (Cleveland, Ohio) |
| ABSTRACT | A method of treating a fungal infection in a subject including administering to the subject a therapeutically effective amount of a thioredoxin protein inhibitor to treat the fungal infection in the subject. |
| FILED | Thursday, April 18, 2013 |
| APPL NO | 14/395377 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/10 (20130101) A61K 31/4164 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603841 | Anderson, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rush University Medical Center (Chicago, Illinois) |
| ASSIGNEE(S) | RUSH UNIVERSITY MEDICAL CENTER (Chicago, Illinois) |
| INVENTOR(S) | Robert Anthony Anderson, Jr. (Brookline, Massachusetts); Calvin J. Chany, II (Alexander, North Carolina) |
| ABSTRACT | A new class of anti-microbial agents and methods for preventing or reducing the risk of sexually transmitted infections and/or diseases is provided. Preferably, these anti-microbial agents are also contraceptive and, thus, also prevent or reduce the risk of unplanned pregnancies. The anti-microbial agents comprise a delivery vector having anti-microbial activity (and preferably contraceptive activity) coupled with a nitric oxide donor moiety. |
| FILED | Thursday, December 10, 2015 |
| APPL NO | 14/965276 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 31/19 (20130101) A61K 31/21 (20130101) A61K 31/24 (20130101) A61K 31/192 (20130101) A61K 31/215 (20130101) A61K 31/216 (20130101) A61K 31/4245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603844 | Rosen et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Eliot M Rosen (Fairfax, Virginia); York A Tomita (Bethesda, Maryland) |
| ABSTRACT | The present invention provides methods of inhibiting abnormal growth of cells, with the methods comprising contacting the cells with at least one of the sensitizing compounds disclosed herein in an amount sufficient to inhibit cell growth. The present invention also provides methods of treating and/or reducing the likelihood of being diagnosed with breast cancer, with the methods comprising administering to a subject in need of treatment thereof at least one of the sensitizing compounds disclosed herein. |
| FILED | Tuesday, October 22, 2013 |
| APPL NO | 14/437484 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/55 (20130101) A61K 31/55 (20130101) A61K 31/135 (20130101) A61K 31/135 (20130101) A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/138 (20130101) A61K 31/138 (20130101) A61K 31/404 (20130101) A61K 31/404 (20130101) A61K 31/421 (20130101) A61K 31/421 (20130101) A61K 31/565 (20130101) A61K 31/565 (20130101) A61K 31/4453 (20130101) Original (OR) Class A61K 31/4453 (20130101) A61K 31/4535 (20130101) A61K 31/4535 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603850 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Xiaodong Wang (Chapel Hill, North Carolina); Stephen Frye (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention includes pyrazolopyrimidine compounds of Formula I that selectively inhibit Mer tyrosine kinase (MerTK) activity and/or Tyro3 tyrosine kinase activity, and use of these pyrazolopyrimidine compounds as anti-cancer agents, immunostimulatory and immunomodulatory agents, anti-platelet agents, anti-infective agents, and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms. |
| FILED | Friday, April 03, 2015 |
| APPL NO | 14/678678 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/551 (20130101) A61K 31/5377 (20130101) A61K 31/5513 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) C07D 487/04 (20130101) C07D 487/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603862 | Sauve et al. |
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| FUNDED BY |
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| APPLICANT(S) | Anthony Sauve (New Rochelle, New York); Yana Cen (New York, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Anthony Sauve (New Rochelle, New York); Yana Cen (New York, New York) |
| ABSTRACT | The invention provides a method of increasing a deacetylase activity of SIRT5 by contacting SIRT5 with an agent that binds SIRT5 and reduces the Km of SIRT5 for a substrate, thereby increasing the deacetylase activity of SIRT5. The invention also provides a method for treating a urea cycle disorder in a mammal, as well as a method of assaying a sirtuin modulator. |
| FILED | Tuesday, December 14, 2010 |
| APPL NO | 13/516190 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/341 (20130101) A61K 31/341 (20130101) A61K 31/443 (20130101) A61K 31/443 (20130101) A61K 31/706 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 405/04 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603873 | Caligiuri et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Michael A. Caligiuri (Columbus, Ohio); Jianhua Yu (Columbus, Ohio); Shun He (Columbus, Ohio); Rossana Trott (Columbus, Ohio) |
| ABSTRACT | Methods and compositions involving miR-122, miR-15b, miR-21, and miR-155, which are useful for the treatment of various diseases, such as cancers, are described. Further described are methods and compositions useful for increasing, activating, or regulating NK cells and surface antigens. |
| FILED | Tuesday, December 03, 2013 |
| APPL NO | 14/649054 |
| ART UNIT | 1674 — Organic Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/15 (20130101) A01K 2217/052 (20130101) A01K 2217/075 (20130101) A01K 2227/00 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) A01K 2267/0337 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/5161 (20130101) A61K 31/7105 (20130101) A61K 31/7105 (20130101) A61K 35/17 (20130101) Original (OR) Class A61K 38/20 (20130101) A61K 38/20 (20130101) A61K 38/21 (20130101) A61K 38/21 (20130101) A61K 38/208 (20130101) A61K 38/208 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 38/2086 (20130101) A61K 38/2086 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2330/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603876 | Blaser et al. |
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| FUNDED BY |
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| APPLICANT(S) | Martin J. Blaser (New York, New York); Ilseung Cho (New York, New York); Laura M. Cox (Morgan Hill, California) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Martin J. Blaser (New York, New York); Ilseung Cho (New York, New York); Laura M. Cox (Morgan Hill, California) |
| ABSTRACT | The present invention relates to characterizing changes in mammalian bacterial gastrointestinal, cutaneous and nasal microbiota associated with antibiotic treatment and various disease conditions (such as asthma, allergy, obesity, metabolic syndrome, gastrointestinal reflux disease (GERD), eosinophilic esophagitis, gastro-esophageal junction adenocarcinomas (GEJAC), infections due to bacteria that are resistant to antibiotics, including Methicillin-resistant Staphylococcus aureus (MRSA), Clostridium difficile, vancomycin-resistant enterococci, etc.) and related diagnostic and therapeutic methods. Therapeutic methods of the invention involve the use of live bacterial inoculants that are capable of restoring healthy mammalian bacterial gastrointestinal, skin, and nasal microbiota. |
| FILED | Friday, September 25, 2009 |
| APPL NO | 12/566965 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 35/741 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603894 | Cao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lan Cao (Stoughton, Massachusetts); Kamal H. Bouhadir (Beirut, Lebanon); David J. Mooney (Sudbury, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Mississippi) |
| INVENTOR(S) | Lan Cao (Stoughton, Massachusetts); Kamal H. Bouhadir (Beirut, Lebanon); David J. Mooney (Sudbury, Massachusetts) |
| ABSTRACT | The invention provides a solution to the problem of delivering molecules in a physiologically relevant manner to direct cell fate. For example, a Notch ligand molecule is presented in a microenvironment that mimics the environment encountered in vivo. Accordingly, the invention features a cell delivery vehicle comprising a biocompatible hydrogel or polymer and a composition that binds to a Notch receptor and methods of directing cell fate, e.g., stem cell differentiation, using such compositions. |
| FILED | Tuesday, November 08, 2011 |
| APPL NO | 13/883005 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 47/4823 (20130101) A61K 47/48246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603896 | Pereira et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Heloise Anne Pereira (Edmond, Oklahoma); Anne Kasus-Jacobi (Midwest City, Oklahoma); Gina L. Griffith (McAlester, Oklahoma) |
| ABSTRACT | Peptide compounds based on the CAP37 protein are disclosed, along with methods for treating various infections, wounds, and conditions, and methods of promoting healing and acceptance of grafts, using compositions containing these peptides. |
| FILED | Tuesday, December 03, 2013 |
| APPL NO | 14/649485 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 38/14 (20130101) A61K 38/14 (20130101) A61K 38/16 (20130101) A61K 38/16 (20130101) A61K 38/17 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603899 | Mao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jeremy J. Mao (Closter, New Jersey); Wenli Zhao (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jeremy J. Mao (Closter, New Jersey); Wenli Zhao (New York, New York) |
| ABSTRACT | Provided is a method of causing a cell to migrate to a scaffold. Also provided is a method of treating a mammal that has a tissue defect. Further provided is a tissue scaffold comprising platelet-derived growth factor (PDGF). Additionally, a method of making a tissue scaffold capable of recruiting a cell is provided. |
| FILED | Monday, October 03, 2011 |
| APPL NO | 13/877272 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 38/1858 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 2300/414 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0663 (20130101) C12N 2501/15 (20130101) C12N 2501/21 (20130101) C12N 2501/105 (20130101) C12N 2501/135 (20130101) C12N 2533/40 (20130101) C12N 2533/54 (20130101) C12N 2533/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603925 | Podack et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Eckhard R. Podack (Coconut Grove, Florida); Taylor H. Schreiber (Miami, Florida); Samia Q. Khan (Miami, Florida) |
| ABSTRACT | Compositions comprising TL1A-Ig fusion proteins and methods of their use, e.g., for the treatment of diseases and disorders associated with antigen-specific immune responses, are described. Also described are combination therapies that include the administration of a TNFRSF25 agonist and an interleukin (e.g., IL-2) and/or an mTOR inhibitor (e.g., rapamycin). |
| FILED | Thursday, February 20, 2014 |
| APPL NO | 14/185295 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/7088 (20130101) A61K 38/20 (20130101) A61K 38/2013 (20130101) A61K 39/395 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 47/48415 (20130101) Peptides C07K 14/52 (20130101) C07K 14/55 (20130101) C07K 16/246 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603949 | McNamara, II et al. |
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| FUNDED BY |
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| APPLICANT(S) | James O. McNamara, II (Iowa City, Iowa); Katie R. Stockdale (Iowa City, Iowa); Lingyan Huang (Coralville, Iowa); Alexander R. Horswill (Iowa City, Iowa); Mark A. Behlke (Coralville, Iowa); Frank J. Hernandez (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); Integrated DNA Technologies, Inc. (Coralville, Iowa) |
| INVENTOR(S) | James O. McNamara, II (Iowa City, Iowa); Katie R. Stockdale (Iowa City, Iowa); Lingyan Huang (Coralville, Iowa); Alexander R. Horswill (Iowa City, Iowa); Mark A. Behlke (Coralville, Iowa); Frank J. Hernandez (Iowa City, Iowa) |
| ABSTRACT | The present invention relates to a rapid detection of microbial-associated nuclease activity with chemically modified nuclease (e.g., ribonuclease) substrates, and probes and compositions useful in detection assays. Accordingly, in certain embodiments, the present invention provides a probe for detecting a microbial endonuclease comprising a substrate oligonucleotide of 2-30 nucleotides in length, a fluorescence-reporter group operably linked to the oligonucleotide, and a fluorescence-quencher group operably linked to the oligonucleotide. The fluorescence-reporter group and the fluorescence-quencher group are separated by at least one RNAse-cleavable residue, e.g., RNA base. |
| FILED | Thursday, August 30, 2012 |
| APPL NO | 14/342338 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0052 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/689 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603971 | Kaplan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David L. Kaplan (Concord, Massachusetts); Monica A. Serban (Melrose, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Monica A. Serban (Melrose, Massachusetts) |
| ABSTRACT | Disclosed herein are pH-dependent silk fibroin-based ionomeric compositions and colloids, and methods of making the same. The state of the silk fibroin ionomeric compositions is reversible and can transform from a gel-like colloid to a more fluid-like solution, or vice versa, upon an environmental stimulus, e.g., pH. Thus, the silk-based ionomeric compositions and colloids can be applied in various industries, ranging from electronic applications to biomedical applications, such as sensors, gel diodes, absorbent materials, drug delivery systems, tissue implants and contrast agents. |
| FILED | Friday, March 04, 2011 |
| APPL NO | 13/582903 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5063 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/26 (20130101) A61L 15/26 (20130101) A61L 15/32 (20130101) A61L 15/42 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/26 (20130101) A61L 27/50 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 2300/00 (20130101) Compositions of Macromolecular Compounds C08L 77/04 (20130101) C08L 77/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603978 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meng Chen (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meng Chen (Columbia, Missouri) |
| ABSTRACT | Coatings, devices and methods are provided, wherein the contacting surface of a medical device with at least one contacting surface for contacting a bodily fluid or tissue, wherein long-lasting and durable bioactive agents or functional groups are deposited on the contacting surface through a unique two-step plasma coating process with deposition of a thin layer of plasma coating using a silicon-containing monomer in the first step and plasma surface modification using a mixture of nitrogen-containing molecules and oxygen-containing molecules in the second step. The two-step plasma coating process enables the implantable medical device to prevent both restenosis and thrombosis under clinical conditions. The invention also relates to surface treatment of metallic and polymeric biomaterials used for making of medical devices with significantly improved clinical performance and durability. |
| FILED | Thursday, December 17, 2015 |
| APPL NO | 14/973401 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/50 (20130101) A61L 31/10 (20130101) Original (OR) Class A61L 31/10 (20130101) A61L 31/14 (20130101) A61L 31/022 (20130101) A61L 2400/18 (20130101) A61L 2420/02 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/62 (20130101) B05D 3/148 (20130101) B05D 5/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) C08L 83/04 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/30 (20130101) C23C 16/56 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115) Y10T 428/31678 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603988 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vital Access Corporation (Salt Lake City, Utah) |
| ASSIGNEE(S) | Vital Access Corporation (Salt Lake City, Utah) |
| INVENTOR(S) | Nathaniel P. Young (Salt Lake City, Utah); Trent J. Perry (Kaysville, Utah); Duane D. Blatter (Salt Lake City, Utah); Christopher M. Phillips (Salt Lake City, Utah); Mark A. Crawford (Sandy, Utah); G. Doug Smith (Sandy, Utah); Steven Johnson (Lehi, Utah) |
| ABSTRACT | Ports for accessing vessels within a patient include passageways that can guide needles or other access devices directly into the vessels. The ports can be implanted subcutaneously within a patient. Some ports may be used in the creation and use of vascular access buttonholes. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 13/723763 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 17/3423 (20130101) A61B 2017/00641 (20130101) A61B 2017/00654 (20130101) A61B 2017/3425 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/14 (20130101) A61M 1/3653 (20130101) Original (OR) Class A61M 1/3659 (20140204) A61M 1/3661 (20140204) A61M 39/0208 (20130101) A61M 2039/0223 (20130101) A61M 2039/0226 (20130101) A61M 2039/0238 (20130101) A61M 2205/0238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604039 | Judy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jack W. Judy (Los Angeles, California); Hyowon Lee (Los Angeles, California); Marvin Bergsneider (Los Angeles, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jack W. Judy (Los Angeles, California); Hyowon Lee (Los Angeles, California); Marvin Bergsneider (Los Angeles, California) |
| ABSTRACT | A self-clearing actuator configured to be positioned in a pore providing fluid communication into a central lumen of a ventricular catheter body is described. The actuator extends into a central bore via a cantilever beam having a first end emanating at the central bore and a second end terminating at the actuator, wherein the actuator is configured to reciprocate within the central bore between a first position extending downward at an angle into the central bore and a second position substantially at or above the external surface of the catheter. The cantilever beam is stressed, e.g. via a composite compress layer, such that it is preloaded to nominally curve downward to extend the actuator into the second position. The actuator is preferably a magnet responsive to magnetic field such that the magnetic field drives the actuator toward the first position. |
| FILED | Monday, June 20, 2011 |
| APPL NO | 13/164587 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/007 (20130101) A61M 27/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604054 | Thieme et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPE HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Kati Thieme (Kirchhain, Germany); Richard H Gracely (Durham, North Carolina); William Maixner (Chapel Hill, North Carolina); Olivier Georges Monbureau (Carrboro, North Carolina) |
| ABSTRACT | Methods, devices, control modules, and computer readable media are provided for managing acute and chronic pain in subjects. More specifically, a method is provided for reducing pain in a subject that includes delivering to the subject a series of stimuli consisting of both painful and non-painful stimuli. A portion of each of the painful and the non-painful stimuli is delivered to the subject during a systolic phase of the subject's cardiac cycle and the remaining portion of each of the painful and the non-painful stimuli is delivered during a diastolic phase of the subject's cardiac cycle. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/776040 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0402 (20130101) A61B 5/0452 (20130101) A61B 5/0456 (20130101) A61B 5/4836 (20130101) A61B 5/7285 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/3615 (20130101) A61N 1/36014 (20130101) A61N 1/36021 (20130101) Original (OR) Class A61N 1/36067 (20130101) A61N 1/36071 (20130101) A61N 1/36075 (20130101) A61N 1/36082 (20130101) A61N 1/36171 (20130101) A61N 1/36178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604056 | Starr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The United States of America Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Philip A. Starr (Mill Valley, California); Coralie de Hemptinne (San Francisco, California); Jill Ostrem (Greenbrae, California); Nicole Swann (El Cerrito, California) |
| ABSTRACT | The present disclosure provides methods for reducing the clinical presentations of a neurological movement disorder in a subject. Aspects of the methods include measuring cortical local field potentials (LFPs) from the subject's brain, calculating a modulation index related to brain synchronization from the LFPs, and administering deep brain stimulation to the subject if the calculated modulation index is outside of a threshold range. Also provided are devices, systems, and kits that may be used in practicing the subject methods. |
| FILED | Monday, March 21, 2016 |
| APPL NO | 15/076303 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0534 (20130101) A61N 1/36067 (20130101) Original (OR) Class A61N 1/36139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604072 | Brezinski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donna J. Brezinski (Winchester, Massachusetts) |
| ASSIGNEE(S) | LITTLE SPARROWS TECHNOLOGIES LLC (Winchester, Massachusetts) |
| INVENTOR(S) | Donna J. Brezinski (Winchester, Massachusetts) |
| ABSTRACT | Disclosed is a portable phototherapy device capable of emitting electromagnetic radiation of a wavelength and intensity sufficient to obtain a desired phototherapeutic effect to a subject, without being in direct physical contact with said subject. The device is portable, capable of being flattened, folded, rolled, compressed, or otherwise collapsed, to a size smaller than that of its operating size. The device may be of any size or shape, and may optionally comprise a frame support. The device may be powered by a variety of sources, including one or more batteries. The device may be configured to deliver electromagnetic radiation sufficient to obtain one or more of a variety of desired phototherapeutic effects. |
| FILED | Tuesday, March 12, 2013 |
| APPL NO | 13/794891 |
| ART UNIT | 3769 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/06 (20130101) Original (OR) Class A61N 5/0614 (20130101) A61N 5/0618 (20130101) A61N 5/0621 (20130101) A61N 5/0624 (20130101) A61N 2005/0652 (20130101) A61N 2005/0662 (20130101) A61N 2005/0665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604904 | Ojima et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iwao Ojima (Port Jefferson, New York); Dale Deutsch (Stony Brook, New York); Martin Kaczocha (Dix Hills, New York); William T. Berger (Mastic, New York); Robert Rizzo (Huntington, New York); Trent E. Balius (Stony Brook, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Iwao Ojima (Port Jefferson, New York); Dale Deutsch (Stony Brook, New York); Martin Kaczocha (Dix Hills, New York); William T. Berger (Mastic, New York); Robert Rizzo (Huntington, New York); Trent E. Balius (Stony Brook, New York) |
| ABSTRACT | The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, having the structure: |
| FILED | Friday, July 19, 2013 |
| APPL NO | 14/413621 |
| ART UNIT | 1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 67/08 (20130101) C07C 67/08 (20130101) C07C 67/48 (20130101) C07C 69/76 (20130101) C07C 69/753 (20130101) C07C 69/753 (20130101) C07C 69/757 (20130101) Original (OR) Class C07C 211/58 (20130101) C07C 233/11 (20130101) C07C 233/58 (20130101) C07C 235/38 (20130101) C07C 235/40 (20130101) C07C 2101/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604907 | Longo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Regents of The University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Frank M. Longo (Menlo Park, California); Stephen M. Massa (Burlingame, California) |
| ABSTRACT | Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. |
| FILED | Monday, January 27, 2014 |
| APPL NO | 14/165090 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/401 (20130101) A61K 31/4178 (20130101) A61K 38/185 (20130101) Acyclic or Carbocyclic Compounds C07C 215/68 (20130101) Original (OR) Class Peptides C07K 5/0823 (20130101) C07K 5/1016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604923 | Turkson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNIVERSITY OF CENTRAL FLORIDA (Orlando, Florida) |
| ASSIGNEE(S) | H.LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | James Turkson (Honolulu, Hawaii); Said M. Sebti (Tampa, Florida); Wayne Guida (St. Petersburg Beach, Florida); Man Lun Yip (Monrovia, California); Nicholas Lawrence (Tampa, Florida); Harshani Rithma Lawrence (Tampa, Florida); Benjamin Greedy (Somerset, United Kingdom) |
| ABSTRACT | The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S31-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. |
| FILED | Monday, April 07, 2014 |
| APPL NO | 14/246522 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 235/84 (20130101) C07C 309/73 (20130101) C07C 311/19 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5011 (20130101) G01N 33/5088 (20130101) G01N 33/57407 (20130101) G01N 33/57484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604926 | McCurdy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christopher R. McCurdy (Oxford, Mississippi); Christophe Mesangeau (Oxford, Mississippi); Frederick T. Chin (Sunnyvale, California); Michelle L. James (Menlo Park, California); Bin Shen (Mountain View, California); Sanjiv Gambhir (Portola Valley, California) |
| ASSIGNEE(S) | THE UNIVERSITY OF MISSISSIPPI (University, Mississippi) |
| INVENTOR(S) | Christopher R. McCurdy (Oxford, Mississippi); Christophe Mesangeau (Oxford, Mississippi); Frederick T. Chin (Sunnyvale, California); Michelle L. James (Menlo Park, California); Bin Shen (Mountain View, California); Sanjiv Gambhir (Portola Valley, California) |
| ABSTRACT | Compounds having the general formula III′, or IV′ wherein R1 can be a radical of an optionally substituted C-4 to C-7 N-containing heterocycle or a radical of an optionally substituted cyclic or acyclic tertiary amine or isoindoline-1,3-dione: R2,4,5,6 can each independently be any one or combinations of the following moieties, cyano, nitro, acyl, alkyl, amido, azido, isothiocyanate, isocyanate, optionally substituted anilino, halogens, ethers, sulfonamides, thioacyl, nitro, aromatic, heterocyclic, olefinic, acetylene, deuterium, or tritium; Y is S; Z can be either H, O, S, S—R or NR where R groups can be either H, aryls, alkyls, or cycloalkyls; “n” can be 1 to 5 carbons in length and stereoisomers, functional analogs, and pharmaceutically acceptable salts thereof and wherein the moiety bridging R1 and N can be a substituted alkylene, optionally substituted alkenylene or optionally substituted alkynylene and where the alkylene group can include an inserted C3-C5 cycloalkyl group, aromatic, and heterocyclic group; and wherein X is C1-C4 radiohaloalkyl. |
| FILED | Wednesday, June 01, 2011 |
| APPL NO | 13/151084 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0453 (20130101) A61K 51/0455 (20130101) A61K 51/0459 (20130101) A61K 51/0468 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) Original (OR) Class C07D 209/10 (20130101) C07D 209/48 (20130101) C07D 235/26 (20130101) C07D 263/58 (20130101) C07D 265/36 (20130101) C07D 277/68 (20130101) C07D 277/70 (20130101) C07D 279/16 (20130101) C07D 295/13 (20130101) C07D 403/06 (20130101) C07D 405/04 (20130101) C07D 413/06 (20130101) C07D 413/12 (20130101) C07D 417/06 (20130101) C07D 491/20 (20130101) C07D 491/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604945 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Caliper Life Sciences, Inc. (Hopkinton, Massachusetts) |
| ASSIGNEE(S) | Caliper Life Sciences, Inc. (Hopkinton, Massachusetts) |
| INVENTOR(S) | Hao Chen (Columbia, Maryland); Ming Liu (Rockville, Maryland); Qi Su (Columbia, Maryland); Manish Raisinghani (Jamesburg, New Jersey) |
| ABSTRACT | Derivatives of Sydnonimine and its analogues, which bind selectively to dopamine transporter (DAT) proteins are useful for treating and delaying the progression of disorders and illnesses that are alleviated by inhibiting dopamine reuptake. |
| FILED | Wednesday, March 27, 2013 |
| APPL NO | 13/851359 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4245 (20130101) Heterocyclic Compounds C07D 271/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604946 | Sperandio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Vanessa Sperandio (Flower Mound, Texas); John R. Falck (Dallas, Texas) |
| ABSTRACT | The present invention relates to compounds and methods for the treatment of bacterial infections. The compounds and methods involve the disruption of the QseC signaling pathway which modulates the virulence of some bacteria. This methodology for treatment of bacterial infections reduces evolutionary pressure to develop resistance because the bacteria are not killed in the process. |
| FILED | Monday, March 10, 2014 |
| APPL NO | 14/203202 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 277/46 (20130101) C07D 277/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604950 | Kravchenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Vladimir Kravchenko (San Diego, California); Richard J. Ulevitch (La Jolla, California); Kim D. Janda (La Jolla, California) |
| ABSTRACT | The invention is directed to methods of inducing apoptosis, arresting cell cycle, or inhibiting cellular proliferation, or any combination thereof, in a tumor cell, by administration of an effective amount of an N-acyl homoserine lactone analog (AHL), optionally in conjunction with a tumor modulating agent such tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL) to the patient. Novel bioactive analogs of an N-acyl homoserine lactone are also provided. |
| FILED | Wednesday, March 19, 2014 |
| APPL NO | 14/778327 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/341 (20130101) A61K 31/365 (20130101) A61K 31/365 (20130101) A61K 31/396 (20130101) A61K 31/396 (20130101) A61K 38/19 (20130101) A61K 38/177 (20130101) A61K 38/177 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 305/12 (20130101) C07D 307/33 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604958 | Iliopoulos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (, None) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Othon Iliopoulos (Cambridge, Massachusetts); Michael Zimmer (Arlington, Massachusetts) |
| ABSTRACT | The present invention is directed to HIF inhibitors and methods of preventing cell proliferation, reducing inflammation, and treating an angiogenic disease or disorders. |
| FILED | Friday, February 21, 2014 |
| APPL NO | 14/186294 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/38 (20130101) A61K 31/138 (20130101) A61K 31/166 (20130101) A61K 31/167 (20130101) A61K 31/366 (20130101) A61K 31/381 (20130101) A61K 31/382 (20130101) A61K 31/473 (20130101) A61K 31/5575 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 225/16 (20130101) C07C 235/38 (20130101) C07C 237/46 (20130101) Heterocyclic Compounds C07D 219/14 (20130101) C07D 309/38 (20130101) C07D 333/22 (20130101) C07D 333/38 (20130101) C07D 335/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604973 | Burkart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael D. Burkart (San Diego, California); James J. La Clair (San Diego, California); Brian D. Jones (Jupiter, Florida); Alexander Mandel (Mercer Island, Washington); Reymundo Villa (San Diego, California); Januario E. Castro (Carlsbad, California); Manoj Kumar Kashyap (San Diego, California); Deepak Kumar (San Diego, California) |
| ABSTRACT | Provided herein, inter alia, are anticancer polyketides. The uses of the polyketides described herein include treatment of cancer, for example, through regulation of the spliceosome and detection of spliceosome inhibition. |
| FILED | Friday, September 26, 2014 |
| APPL NO | 14/498934 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 313/00 (20130101) C07D 407/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605002 | Moraski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF NOTRE DAME DU LAC (Notre Dame, Indiana) |
| ASSIGNEE(S) | UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana) |
| INVENTOR(S) | Garrett Moraski (Bozeman, Montana); Marvin J. Miller (South Bend, Indiana) |
| ABSTRACT | The invention provides a series of 5,5-heteroaromatic compounds, syntheses thereof, compositions thereof, and methods of using such compounds and compositions. Various embodiments provide methods of killing and/or inhibiting the growth of M. tuberculosis and/or M. avium, and methods of treating, preventing, and/or ameliorating M. tuberculosis and/or M. avium infections in a subject. In various embodiments, the 5,5-heteroaromatic compound is N-(4-(4-chlorophenoxy)benzyl)-2,6-dimethylimidazo[2,1-b]thiazole-5-carboxamide. |
| FILED | Thursday, July 18, 2013 |
| APPL NO | 14/415726 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/2059 (20130101) A61K 9/2866 (20130101) A61K 31/4188 (20130101) Heterocyclic Compounds C07D 513/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605026 | Arora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York); The Ohio State University Research Foundation (Columbus, Ohio); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York); THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (Columbus, Ohio); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Paramjit S. Arora (Cold Spring Harbor, New York); Quintin Pan (Dublin, Ohio); Anna Mapp (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to peptidomimetics for reactivating p53. Methods of using the peptidomimetics are also disclosed. |
| FILED | Tuesday, January 21, 2014 |
| APPL NO | 14/160001 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Peptides C07K 7/56 (20130101) C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605028 | Ebright et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Richard H. Ebright (New Brunswick, New Jersey); Yon W. Ebright (New Brunswick, New Jersey); Yu Feng (New Brunswick, New Jersey); David Degen (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides compounds of formula (I): and salts thereof, wherein X and Y have any of the values defined herein. The compounds inhibit bacterial RNA polymerase, inhibit bacterial growth, and have applications in, analysis of RNA polymerase structure and function, control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, antibacterial therapy, and drug discovery. |
| FILED | Thursday, December 17, 2015 |
| APPL NO | 14/973554 |
| ART UNIT | 1676 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 11/02 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91255 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605032 | McBride et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jere W. McBride (League City, Texas); Christopher K. Doyle (San Rafael, California) |
| ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
| INVENTOR(S) | Jere W. McBride (League City, Texas); Christopher K. Doyle (San Rafael, California) |
| ABSTRACT | The present invention concerns gp19 immunoreactive compositions for E. canis and compositions related thereto, including vaccines, antibodies, polypeptides, peptides, and polynucleotides. In particular, epitopes for E. canis gp19 are disclosed. |
| FILED | Tuesday, August 07, 2007 |
| APPL NO | 12/377926 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/195 (20130101) Original (OR) Class C07K 16/1246 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/29 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605033 | McBride et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Development Foundation (Carson City, Nevada) |
| ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
| INVENTOR(S) | Jere W. McBride (Leauge City, Texas); Christopher Kuyler Doyle (Brussels, Belgium) |
| ABSTRACT | The present invention concerns gp19 immunoreactive compositions for E. canis and compositions related thereto, including vaccines, antibodies, polypeptides, peptides, and polynucleotides. In particular, epitopes for E. canis gp19 are disclosed. |
| FILED | Wednesday, June 03, 2015 |
| APPL NO | 14/729758 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/195 (20130101) Original (OR) Class C07K 16/1246 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/29 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605035 | McBride et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jere W. McBride (League City, Texas); Tian Luo (Galveston, Texas) |
| ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
| INVENTOR(S) | Jere W. McBride (League City, Texas); Tian Luo (Galveston, Texas) |
| ABSTRACT | The present invention concerns VLPT immunoreactive compositions for E. chaffeensis and compositions related thereto, including vaccines, antibodies, polypeptides, peptides, and polynucleotides. In particular, epitopes for E. chaffeensis VLPT are disclosed. |
| FILED | Friday, January 09, 2009 |
| APPL NO | 12/812365 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/0233 (20130101) Peptides C07K 14/29 (20130101) Original (OR) Class C07K 16/1246 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/29 (20130101) G01N 2333/195 (20130101) G01N 2333/43556 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605036 | McBride et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Development Foundation (Carson City, Nevada) |
| ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
| INVENTOR(S) | Jere W. McBride (League City, Texas); Tian Luo (Galveston, Texas) |
| ABSTRACT | The present invention concerns VLPT immunoreactive compositions for E. chaffeensis and compositions related thereto, including vaccines, antibodies, polypeptides, peptides, and polynucleotides. In particular, epitopes for E. chaffeensis VLPT are disclosed. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 14/724136 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/0233 (20130101) Peptides C07K 14/29 (20130101) Original (OR) Class C07K 16/1246 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/29 (20130101) G01N 2333/195 (20130101) G01N 2333/43556 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605042 | Ashe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Karen Hsiao Ashe (North Oaks, Minnesota); Xiaohui Zhao (Woodbury, Minnesota); Michael Anthony Walters (Minneapolis, Minnesota); Derek John Hook (San Diego, California); Morgan Clotaire Paul Le Naour (Minneapolis, Minnesota) |
| ABSTRACT | Disclosed herein are isolated polypeptides, antibody preparations, treatment methods, diagnostic methods, and screening methods related to tauopathy. Generally, the isolated polypeptide includes a core pentapeptide, with the proviso that the isolated polypeptide is not a native full-length tau protein. Generally, the antibody preparations include antibody that specifically binds to SEQ ID NO:12. Generally, the treatment methods include administering to a subject a composition that includes the isolated polypeptide. Generally, the diagnostic methods includes contacting a sample from a subject with an antibody preparation that includes antibody that specifically binds to SEQ ID NO:12, and then detecting a ligand in the sample that specifically binds the antibody preparation. Generally, the screening method includes incubating a mixture of caspase-2, a labeled caspase-2 cleavage substrate, and a test compound under conditions effective to permit the caspase-2 to cleave the caspase-2 cleavage substrate, then determining whether the test compound inhibits cleavage of the substrate by caspase-2. |
| FILED | Monday, November 23, 2015 |
| APPL NO | 14/949246 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4711 (20130101) Original (OR) Class C07K 16/18 (20130101) C07K 2317/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/04 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605044 | Biragyn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Arya Biragyn (Lutherville, Maryland); Kouji Matsushima (Tokyo, Japan); Dolgor Baatar (Parkville, Maryland) |
| ABSTRACT | The instant invention provides methods and compositions for modulation of the immune system. Specifically, the invention provides methods and compositions for increasing T cell mediated immune response useful in the treatment of cancer and chronic infection. |
| FILED | Tuesday, June 24, 2014 |
| APPL NO | 14/313481 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/48261 (20130101) A61K 47/48269 (20130101) Peptides C07K 14/521 (20130101) Original (OR) Class C07K 14/523 (20130101) C07K 14/7158 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1077 (20130101) Enzymes C12Y 204/02036 (20130101) C12Y 301/27005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605046 | Mosnier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California); Laurent O. Mosnier (San Diego, California); John H. Griffin (Del Mar, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Laurent O. Mosnier (San Diego, California); John H. Griffin (Del Mar, California) |
| ABSTRACT | The present invention provides novel PAR 1 derived cytoprotective oligopeptides or polypeptides which typically contain at least the first 4 N-terminal residues that are substantially identical to the corresponding N-terminal residues of Met1-Arg46 deleted human PAR 1 sequence. These cytoprotective oligopeptides or polypeptides are capable of activating PAR 1 and promoting PAR 1 cytoprotective signaling activities. The invention also provides engineered cells or transgenic non-human animals which harbor in their genome an altered PAR 1 gene that is resistant to cleavage at Arg41 and/or Arg46 residues. Additionally provided in the invention are methods of screening candidate compounds to identity additional cytoprotective compounds or cytoprotective proteases. The invention further provides therapeutic use or methods of employing a PAR 1 derived cytoprotective oligopeptide or polypeptide to treat conditions associated with tissue injuries or undesired apoptosis. |
| FILED | Wednesday, November 07, 2012 |
| APPL NO | 14/356692 |
| ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/177 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605047 | Maron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Womens's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bradley Maron (Sharon, Massachusetts); Joseph Loscalzo (Dover, Massachusetts); Jane Leopold (Chestnut Hill, Massachusetts) |
| ABSTRACT | The technology described herein is directed to agents that reduce the level of oxidant-modified ET-B Cys405, Cys403, or Cys402 and the identification and use of such agents for, e.g. to treat hypertension. |
| FILED | Wednesday, April 03, 2013 |
| APPL NO | 14/390408 |
| ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/177 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 2333/726 (20130101) G01N 2440/20 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605049 | Campana et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| INVENTOR(S) | Dario Campana (Singapore, Singapore); Chihaya Imai (Niigata, Japan) |
| ABSTRACT | The present invention relates to a chimeric receptor capable of signaling both a primary and a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway without binding to the natural ligand. The cytoplasmic domain of the receptor contains a portion of the 4-1BB signaling domain. Embodiments of the invention relate to polynucleotides that encode the receptor, vectors and host cells encoding a chimeric receptor, particularly including T cells and natural killer (NK) cells and methods of use. |
| FILED | Tuesday, June 10, 2014 |
| APPL NO | 14/301122 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) Peptides C07K 14/47 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) Original (OR) Class C07K 16/2866 (20130101) C07K 16/2878 (20130101) C07K 16/2896 (20130101) C07K 2319/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) C12N 2501/23 (20130101) C12N 2502/11 (20130101) C12N 2502/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605050 | Wang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Lai-Xi Wang (Ellicott City, Maryland) |
| ABSTRACT | A chemoenzymatic method for the preparation of a homogeneous glycoprotein or glycopeptide, including (a) providing an acceptor selected from the group consisting of GlcNAc-protein and GlcNAc-peptide; and (b) reacting the acceptor with a donor substrate including an activated oligosaccharide moiety, in the presence of a catalyst comprising endoglycosidase (ENGase), to transfer the oligosaccharide moiety to the acceptor and yield the homogeneous glycoprotein or glycopeptide. The donor substrate includes, in a specific implementation, a synthetic oligosaccharide oxazoline. A related method of glycoprotein or glycopeptide remodeling with a predetermined natural N-glycan or a tailor-made oligosaccharide moiety, and a method of remodeling an antibody including a heterogeneous sugar chain, are also described. The disclosed methodology enables glycoprotein drugs to be modified for prolonged half-life in vivo, reduced immunogenicity, and enhanced in vivo activity, and for targeting and drug delivery. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 14/554249 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 16/00 (20130101) Original (OR) Class C07K 17/10 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605054 | Brady et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Scott T. Brady (Chicago, Illinois); Lester I. Binder (Chicago, Illinois); Gerardo Andres Morfini (Chicago, Illinois); Nicholas M. Kanaan (Grand Rapids, Michigan); Nichole E. LaPointe (Santa Barbara, California) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Scott T. Brady (Chicago, Illinois); Lester I. Binder (Chicago, Illinois); Gerardo Andres Morfini (Chicago, Illinois); Nicholas M. Kanaan (Grand Rapids, Michigan); Nichole E. LaPointe (Santa Barbara, California) |
| ABSTRACT | The present invention is a composition and method for the prevention and treatment of a tauopathy. The composition of the invention includes N-terminal amino acid residues of the tau protein, which have been identified as being involved in toxic activation of a PP1/GSK3 signaling cascade and inhibition of fast axonal transport in human tauopathies. |
| FILED | Monday, October 18, 2010 |
| APPL NO | 12/906617 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4711 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/32 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 2333/912 (20130101) G01N 2333/4709 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605057 | Scherer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Philipp Erich Scherer (Southlake, Texas); Jiyoung Park (Dallas, Texas); Zhiqiang An (Pearland, Texas) |
| ABSTRACT | Aspects of the present invention relate to methods and reagents for increasing chemosensitivity to platinum-based chemotherapy. In one aspect, a method of increasing chemosensitivity to platinum-based chemotherapy is provided, comprising administering to a patient in need thereof an effective amount of an endotrophin-neutralizing agent. The agent can be a monoclonal antibody, or fragment thereof, capable of binding to the C5 domain of the alpha3 chain of collagen VI. In some embodiments, the method can further include administering an effective amount of thiazolidinedione to said patient. |
| FILED | Tuesday, June 17, 2014 |
| APPL NO | 14/306784 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 49/0004 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605074 | Shah |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Khalid Shah (Andover, Massachusetts) |
| ABSTRACT | The technology described herein is directed to methods and compositions directed to the treatment of cancer, e.g. using multifunctional receptor targeted cancer therapeutics. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 14/423512 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 39/39558 (20130101) A61K 48/00 (20130101) Peptides C07K 14/71 (20130101) C07K 14/525 (20130101) C07K 14/4747 (20130101) C07K 16/30 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605076 | Jaiswal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, Connecticut) |
| INVENTOR(S) | Siddhartha Jaiswal (San Francisco, California); Irving L. Weissman (Stanford, California); Ravindra Majeti (Palo Alto, California); Mark P. Chao (Mountain View, California) |
| ABSTRACT | Methods are provided to manipulate phagocytosis of cancer cells, including e.g. leukemias, solid tumors including carcinomas, etc. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/054914 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 47/4863 (20130101) A61K 47/48569 (20130101) A61K 47/48607 (20130101) A61K 47/48615 (20130101) A61K 47/48623 (20130101) A61K 47/48638 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/18 (20130101) C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2896 (20130101) C07K 16/3038 (20130101) C07K 16/3046 (20130101) C07K 16/3053 (20130101) C07K 16/3061 (20130101) Original (OR) Class C07K 16/3069 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605078 | Bertozzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Carolyn Bertozzi (Berkeley, California); Paresh Agarwal (Berkeley, California); Ellen M. Sletten (Somerville, Massachusetts) |
| ABSTRACT | Aldehyde- and ketone-functionalized proteins are promising new substrates for the development of chemically modified biotherapeutics and protein-based materials. Their reactive carbonyl groups are typically conjugated with a-effect nucleophiles, such as substituted hydrazines and alkoxyamines, to generate hydrazones and oximes, respectively. However, the resulting C═N linkages are susceptible to hydrolysis under physiologically relevant conditions, which limits their utility in biological systems. Here we introduce a Pictet-Spengler ligation that is based on the classic Pictet-Spengler reaction of aldehydes and tryptamine nucleophiles. The ligation exploits the bioorthogonal reaction of aldehydes and alkoxyamines to form an intermediate oxyiminium ion; this intermediate undergoes intramolecular C—C bond formation with an indole nucleophile to form an oxacarboline product that is hydrolytically stable. The reaction was utilized for site-specific chemical modification of glyoxal- and formylglycine-functionalized proteins, including an aldehyde-tagged variant of the therapeutic monoclonal antibody Herceptin. In conjunction with techniques for site-specific introduction of aldehydes into proteins, the Pictet-Spengler ligation offers a new means to generate stable bioconjugates for medical and materials applications. |
| FILED | Friday, November 15, 2013 |
| APPL NO | 14/443149 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Heterocyclic Compounds C07D 209/12 (20130101) C07D 311/92 (20130101) C07D 405/12 (20130101) C07D 495/04 (20130101) C07D 498/04 (20130101) Peptides C07K 16/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605083 | Parkos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charles A. Parkos (Norcross, Georgia); Dominique A. Weber (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Charles A. Parkos (Norcross, Georgia); Dominique A. Weber (Atlanta, Georgia) |
| ABSTRACT | Disclosed are specific binding agents such as antibodies and chimera that bind to JAM-like protein. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods related thereto. |
| FILED | Friday, August 10, 2012 |
| APPL NO | 14/238556 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/42 (20130101) Original (OR) Class C07K 16/2803 (20130101) C07K 2317/33 (20130101) C07K 2317/75 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605246 | Haurwitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Rachel E. Haurwitz (Berkeley, California); Jennifer A. Doudna (Berkeley, California); Blake Wiedenheft (Oakland, California); Martin Jinek (Berkeley, California) |
| ABSTRACT | The present disclosure provides variant Csy4 endoribonucleases, nucleic acids encoding the variant Csy4 endoribonucleases, and host cells genetically modified with the nucleic acids. The variant Csy4 endoribonucleases find use in a variety of applications, which are also provided. The present disclosure also provides methods of detecting a specific sequence in a target polyribonucleotide; and methods of regulating production of a target RNA in a eukaryotic cell. |
| FILED | Wednesday, June 10, 2015 |
| APPL NO | 14/735383 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/22 (20130101) C07K 14/8117 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6823 (20130101) C12Q 2521/313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605251 | Lenz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Laurel L. Lenz (Denver, Colorado); Rebecca L. Schmidt (Glendale, Colorado) |
| ASSIGNEE(S) | NATIONAL JEWISH HEALTH (Denver, Colorado) |
| INVENTOR(S) | Laurel L. Lenz (Denver, Colorado); Rebecca L. Schmidt (Glendale, Colorado) |
| ABSTRACT | Embodiments herein report compositions, methods and uses for inducing an innate immune response in a subject. Embodiments herein also generally report compositions, methods and uses for bacterial-derived peptides to induce an innate immune response in a subject having a bacterial or viral disorder and/or cancer. In certain embodiments, compositions herein concern derivatives of p60 protein of Listeria monocytogenes. |
| FILED | Wednesday, November 10, 2010 |
| APPL NO | 13/509269 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/208 (20130101) A61K 39/39 (20130101) A61K 39/0208 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2039/55516 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
09605253 — Electrokinetic confinement of neurite growth for dynamically configurable neural networks
| US 09605253 | Voldman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Centre National de la Recherche Scientifique (Paris, France) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France) |
| INVENTOR(S) | Joel Voldman (Belmont, Massachusetts); Thibault Honegger (Boston, Massachusetts); David Peyrade (Moirans, France) |
| ABSTRACT | Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance cue. The physical guidance cue may be used to alter the growth of the neurite and may be temporally and spatially dynamic, such that neurite growth may be altered in a spatial and/or temporal manner. Dynamic control of neurite growth may be used to form directional neural connections, intersections, and/or overlaps. |
| FILED | Tuesday, January 14, 2014 |
| APPL NO | 14/154797 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/205 (20130101) A61N 1/326 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/34 (20130101) C12M 35/02 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 13/00 (20130101) Original (OR) Class C12N 2529/00 (20130101) C12N 2533/54 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09605254 — Electrokinetic confinement of neurite growth for dynamically configurable neural networks
| US 09605254 | Voldman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Centre National de la Recherche Scientifique (Paris, France) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France) |
| INVENTOR(S) | Joel Voldman (Belmont, Massachusetts); Thibault Honegger (Boston, Massachusetts); David Peyrade (Moirans, France) |
| ABSTRACT | Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance cue. The physical guidance cue may be used to alter the growth of the neurite and may be temporally and spatially dynamic, such that neurite growth may be altered in a spatial and/or temporal manner. Dynamic control of neurite growth may be used to form directional neural connections, intersections, and/or overlaps. |
| FILED | Tuesday, January 14, 2014 |
| APPL NO | 14/154823 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/205 (20130101) A61N 1/326 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/34 (20130101) C12M 35/02 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 13/00 (20130101) Original (OR) Class C12N 2529/00 (20130101) C12N 2533/54 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605266 | Rossi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | John Rossi (Alta Loma, California); Jiehua Zhou (Monrovia, California); Marc Weinberg (Encinitas, California); Kevin Morris (Sierra Madre, California) |
| ABSTRACT | Provided herein are fluoropyrimidine-modified RNA aptamers capable of binding CCR5. The compositions and methods provided herein are, inter alia, useful for the delivery of anti-viral drugs (e.g., siRNAs) and preventing HIV entry into a target cell. |
| FILED | Thursday, July 16, 2015 |
| APPL NO | 14/801710 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605275 | Tang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Altimmune Inc. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | ALTIMMUNE INC. (Gaithersburg, Maryland) |
| INVENTOR(S) | De-Chu C. Tang (Birmingham, Alabama) |
| ABSTRACT | The present invention shows that intranasal administration of E1/E3-defective adenovirus particles may confer rapid and broad protection against viral and bacterial pathogens in a variety of disease settings. Protective responses lasted for many weeks in a single-dose regimen in animal models. When a pathogen-derived antigen gene was inserted into the E1/E3-defective adenovirus genome, the antigen-induced protective immunity against the specific pathogen was elicited before the adenovirus-mediated protective response declined away, thus conferring rapid, prolonged, and seamless protection against pathogens. In addition to E1/E3-defective adenovirus, other bioengineered non-replicating vectors encoding pathogen-derived antigens may also be developed into a new generation of rapid and prolonged immunologic-therapeutic (RAPIT). |
| FILED | Monday, December 30, 2013 |
| APPL NO | 14/143104 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/07 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/155 (20130101) A61K 2039/58 (20130101) A61K 2039/543 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/10034 (20130101) C12N 2710/10043 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605276 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Frank R Jones (Seattle, Washington); Elizabeth Gabitzsch (Seattle, Washington) |
| ASSIGNEE(S) | Etubics Corporation (Seattle, Washington) |
| INVENTOR(S) | Frank R Jones (Seattle, Washington); Elizabeth Gabitzsch (Seattle, Washington) |
| ABSTRACT | Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 14/422504 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/53 (20130101) A61K 2039/545 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/70503 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2799/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605297 | Zhuang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zhihao Zhuang (Wilmington, Delaware); Guorui Li (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF DELAWARE (Newark, Delaware) |
| INVENTOR(S) | Zhihao Zhuang (Wilmington, Delaware); Guorui Li (Baltimore, Maryland) |
| ABSTRACT | Deubiquitinating enzyme (DUB) probes are provided that resemble native diubiquitin (diUB) with a similar linkage size and that may contain a Michael acceptor for trapping the DUB active-site cysteine. For example, both K63- and K48-linked diubiquitin probes are generated using a facile chemical ligation method, utilizing the linker compound 3-(2-(bromomethyl)-1,3-dioxolan-2-yl)prop-2-en-1-amine. The diUb probes are capable of labelling DUBs from different families and may be employed to reveal intrinsic linkage specificities of DUBs. |
| FILED | Wednesday, October 15, 2014 |
| APPL NO | 15/029519 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Heterocyclic Compounds C07D 317/28 (20130101) Peptides C07K 1/10 (20130101) C07K 14/47 (20130101) C07K 2319/50 (20130101) C07K 2319/95 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/95 (20130101) G01N 2440/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605298 | Craighead et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Harold G. Craighead (Ithaca, New York); Benjamin R. Cipriany (Wappingers Falls, New York); Stephen Levy (Ithaca, New York); Paul Soloway (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Harold G. Craighead (Ithaca, New York); Benjamin R. Cipriany (Wappingers Falls, New York); Stephen Levy (Ithaca, New York); Paul Soloway (Ithaca, New York) |
| ABSTRACT | Systems and methods are provided for high speed sorting of objects in a continuous body of fluid. The object can be analyzed within one or more interrogation volumes that allow for simultaneous or time-correlated measurement of the object's properties. A processor can interpret the properties of the object and then measured and then direct the object to one of a plurality of downstream flow paths. In some embodiments, the sorting of the object is based on two or more properties of the object. The sorting process can be repeated to create a network of sorting events. |
| FILED | Friday, August 06, 2010 |
| APPL NO | 13/389259 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0663 (20130101) B01L 2300/0654 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2561/113 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605320 | Alizadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arash Ash Alizadeh (San Mateo, California); Dan Denney (Fremont, California); Ronald Levy (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Arash Ash Alizadeh (San Mateo, California); Dan Denney (Fremont, California); Ronald Levy (Stanford, California) |
| ABSTRACT | Predictive biomarkers identify those patients suffering from immunoglobulin positive (Ig+) B lineage malignancies that are responsive to active immunotherapy, where the active immunotherapy comprises vaccination with a tumor-specific idiotype-immunogen. It is shown herein that patient responsiveness to the idiotype-immunogen is dependent upon the sequence of the immunogen, where an immunogen having a low number of tyrosine residues in the CDR1 (herein termed CDR1-Y10) regions of one or both of the immunogen heavy and light chains is predictive of a positive anti-tumor response, while a high number of CDR1 tyrosine residues (herein termed CDR1-Yhi) is predictive of a low anti tumor response. |
| FILED | Tuesday, January 10, 2012 |
| APPL NO | 13/978360 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/686 (20130101) G01N 33/57426 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606039 | Ogle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brenda M. Ogle (Fitchburg, Wisconsin); Luis A. Fernandez (Madison, Wisconsin); Kevin W. Eliceiri (Madison, Wisconsin); Matthew S. Hanson (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brenda M. Ogle (Fitchburg, Wisconsin); Luis A. Fernandez (Madison, Wisconsin); Kevin W. Eliceiri (Madison, Wisconsin); Matthew S. Hanson (Madison, Wisconsin) |
| ABSTRACT | A flow cytometry system suitable for characterizing multicellular aggregates during culture and before implantation combines a low shear flow channel with a multiphoton laser scanning microscope, the latter permitting the characterization of interior and exterior cells in optical isolation from other cells for a representative sampling of fluorescent activity. Imaging capabilities permit sophisticated statistical measurements reflecting individual cell characteristics. |
| FILED | Wednesday, September 16, 2009 |
| APPL NO | 12/561102 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606082 | Mellors et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Scott Mellors (Carrboro, North Carolina); Erin Anne Redman (Carrboro, North Carolina); John Michael Ramsey (Chapel Hill, North Carolina) |
| ABSTRACT | Methods that allow independently applied pressures to a BGE reservoir and a sample reservoir for pressure-driven injection that can inject a discrete sample plug into a separation channel that does not require voltage applied to the sample reservoir and can allow for in-channel focusing methods to be used. The methods are particularly suitable for use with a mass spectrometer. |
| FILED | Monday, January 04, 2016 |
| APPL NO | 14/987326 |
| ART UNIT | 1759 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 2300/0864 (20130101) B01L 2400/049 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) B01L 2400/0487 (20130101) B01L 2400/0622 (20130101) B01L 2400/0666 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44743 (20130101) Original (OR) Class G01N 27/44791 (20130101) G01N 30/7266 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606086 | Ding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Xiaoyun Ding (State College, Pennsylvania); Tony Jun Huang (State College, Pennsylvania) |
| ABSTRACT | An apparatus for manipulating particles within a fluid sample includes a substrate having a substrate surface. A surface acoustic wave (SAW) generator generates a SAW within a SAW region of the substrate surface. The SAW has an SAW direction aligned with a pressure node. A channel is configured to receive the fluid sample and the fluid sample has a flow direction which is at an oblique angle to the SAW direction. |
| FILED | Wednesday, July 31, 2013 |
| APPL NO | 13/955709 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0864 (20130101) B01L 2400/0436 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 29/02 (20130101) Original (OR) Class G01N 29/222 (20130101) G01N 2015/0019 (20130101) G01N 2015/1006 (20130101) G01N 2291/0423 (20130101) G01N 2291/02466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606106 | O'Day et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Elizabeth M. O'Day (Braintree, Massachusetts); Judy Lieberman (Brookline, Massachusetts); Gerhard Wagner (Chestnut Hill, Massachusetts) |
| ABSTRACT | Methods that enable one to specifically measure the metabolic product of a particular molecule in relatively few cells, e.g. primary cells, are described. The methods involve optionally preloading cells with labeled substrate (e.g. labeled by 13C, 15N, or 31P). The methods allow for easy identification of metabolites that are differentially generated in cells of different phenotypes. The new methods for unbiased multi-dimensional NMR screening and rapid and efficient analysis of the NMR screening identify differentially expressed metabolites in different cell or tissue types. Analysis of the differentially expressed metabolites can present unique druggable targets to which small molecule therapeutics can be designed. |
| FILED | Monday, February 11, 2013 |
| APPL NO | 14/377257 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) G01N 33/5005 (20130101) G01N 33/5011 (20130101) Original (OR) Class G01N 33/5038 (20130101) G01N 2458/15 (20130101) G01N 2500/10 (20130101) G01N 2570/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/465 (20130101) G01R 33/4633 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606108 | Krishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ramaswamy Krishnan (Cambridge, Massachusetts); Allen Ehrlicher (Boston, Massachusetts); James Butler (Brookline, Massachusetts); David A. Weitz (Bolton, Massachusetts); Jeffrey J. Fredberg (Sharon, Massachusetts); Chan Young Park (Belmont, Massachusetts) |
| ABSTRACT | A platform for biological assays includes a base substrate providing structural support to the platform, at least one surface of the base substrate coated with position markers, a first deformable layer positioned on top of the base substrate, and a second deformable layer positioned on top of the first deformable layer, the second deformable layer embedded with deformation markers. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 14/358891 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/24 (20130101) B32B 2037/243 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/20 (20130101) C12M 25/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) G01N 33/5029 (20130101) Original (OR) Class G01N 2500/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606123 | Slack-Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jill K. Slack-Davis (Free Union, Virginia); Kimberly A. Kelly (Crozet, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Jill K. Slack-Davis (Free Union, Virginia); Kimberly A. Kelly (Crozet, Virginia) |
| ABSTRACT | The present invention provides compositions and methods useful for diagnosing, monitoring the progression, identifying the location, and monitoring the treatment response in ovarian cancer based on detecting and locating VCAM-1 expression. |
| FILED | Friday, March 28, 2014 |
| APPL NO | 14/228828 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/088 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57449 (20130101) Original (OR) Class G01N 2333/70542 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606124 | Wicha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Max S. Wicha (Ann Arbor, Michigan); Christophe Ginestier (Marseille, France) |
| ABSTRACT | The present invention provides methods of treating cancer by administering an IL8-CXCR1 pathway inhibitor (e.g., an anti-CXCR1 antibody or Repertaxin) alone or in combination with an additional chemotherapeutic agent such that non-tumorigenic and tumorigenic cancer cells in a subject are killed. The present invention also provides compositions and methods for detecting the presence of and isolating solid tumor stem cells in a patient (e.g., based on the presence of CXCR1 or FBXO21). |
| FILED | Wednesday, December 10, 2014 |
| APPL NO | 14/566415 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/337 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5743 (20130101) G01N 33/57407 (20130101) G01N 33/57415 (20130101) G01N 33/57434 (20130101) G01N 33/57449 (20130101) G01N 33/57492 (20130101) Original (OR) Class G01N 2333/7158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606126 | Wiener et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael C. Wiener (Charlottesville, Virginia); James M. Vergis (Gaithersburg, Maryland) |
| ASSIGNEE(S) | University of Virgina Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Michael C. Wiener (Charlottesville, Virginia); James M. Vergis (Gaithersburg, Maryland) |
| ABSTRACT | The invention provides methods to assess protein stability and to obtain sizing information. In one aspect, the screen comprises a 94 detergent panel and a series of MWCO filtered microplates. A protein of interest is bound to an affinity matrix and aliquoted into a 96-well microplate. Wells containing the immobilized protein are washed in the new detergent and then eluted in the new detergent into a collection plate. Protein not stable in the new detergent is precipitated on the resin and not present in the elutions. Half of the elution is passed through a high (i.e., 300 kDa) MWCO microplate and the other half through a low (i.e., 100 kDa) MWCO microplate. Elutions from the microplates are spotted on a nitrocellulose membrane, visualized by Western analysis (or by some other method), and quantified. The high MWCO provides stability readout and the ratio of low/high kDa provides sizing information. |
| FILED | Tuesday, June 29, 2010 |
| APPL NO | 13/376729 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Separation B01D 15/3804 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6803 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606131 | Thadhani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Beth Isreal Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Ravi Thadhani (Boston, Massachusetts); S. Ananth Karumanchi (Chestnut Hill, Massachusetts); Anders Hayden Berg (Dedham, Massachusetts); Ishir Bhan (West Newton, Massachusetts) |
| ABSTRACT | Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency. |
| FILED | Monday, May 11, 2015 |
| APPL NO | 14/709315 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/59 (20130101) A61K 31/592 (20130101) A61K 31/593 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606209 | Ernst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas Michael Ernst (Honolulu, Hawaii); Oliver Speck (Magdeburg, Germany) |
| ASSIGNEE(S) | KINETICOR, INC. (Honolulu, Hawaii) |
| INVENTOR(S) | Thomas Michael Ernst (Honolulu, Hawaii); Oliver Speck (Magdeburg, Germany) |
| ABSTRACT | Systems, methods, and devices for intra-scan motion correction to compensate not only from one line or acquisition step to the next, but also within each acquisition step or line in k-space. The systems, methods, and devices for intra-scan motion correction can comprise updating geometry parameters, phase, read, and/or other encoding gradients, applying a correction gradient block, and/or correcting residual errors in orientation, pose, and/or gradient/phase. |
| FILED | Friday, August 24, 2012 |
| APPL NO | 13/594563 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/56509 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607017 | Debray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Saumya K. Debray (Tucson, Arizona); Richard T. Snodgrass (Tucson, Arizona); Rui Zhang (Torrance, California) |
| ABSTRACT | Systems and methods for utilizing relation- and query-specific information to specialize DBMS code at runtime based on identifying runtime locally invariant variables. Runtime invariant is often of the form of variables in code that hold values that are constant during a portion of code execution. Micro-specialization is applied to eliminate from the original program unnecessary code such as branching statements that reference local invariant(s) in branch-condition evaluation. The resulting specialized code reduces the code complexity as well as significantly improves the runtime efficiency during code execution. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 14/368265 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30289 (20130101) Original (OR) Class G06F 17/30321 (20130101) G06F 17/30383 (20130101) G06F 17/30474 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607202 | Sammak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul J. Sammak (Pittsburgh, Pennsylvania); Rami Mangoubi (Newton, Massachusetts); Teresa M. Erb (Pittsburgh, Pennsylvania); Sara Mucko (Philadelphia, Pennsylvania); Mukund Desai (Needham, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Paul J. Sammak (Pittsburgh, Pennsylvania); Rami Mangoubi (Newton, Massachusetts); Teresa M. Erb (Pittsburgh, Pennsylvania); Sara Mucko (Philadelphia, Pennsylvania); Mukund Desai (Needham, Massachusetts) |
| ABSTRACT | Methods for inducing differentiation of stem cells into trophectoderm, neurectoderm, or progeny cells thereof are described, and mathematical and statistical image analysis methods and systems, for example, to identify differentiated cells and screen for agents which modulate differentiation are provided for separate or combined use. |
| FILED | Friday, December 17, 2010 |
| APPL NO | 12/972346 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00 (20130101) Original (OR) Class G06K 9/00147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607392 | Crainiceanu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); The United States of America, as represented by the Secretary Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Ciprian M. Crainiceanu (Baltimore, Maryland); Elizabeth M. Sweeney (Baltimore, Maryland); Russell T. Shinohara (Baltimore, Maryland); Arthur J. Goldsmith (Baltimore, Maryland); Daniel Reich (Washington, District of Columbia); Colin Shea (Great Falls, Virginia) |
| ABSTRACT | A method of automatically detecting tissue abnormalities in images of a region of interest of a subject includes obtaining first image data for the region of interest of the subject, normalizing the first image data based on statistical parameters derived from at least a portion of the first image data to provide first normalized image data, obtaining second image data for the region of interest of the subject, normalizing the second image data based on statistical parameters derived from at least a portion of the second image data to provide second normalized image data, processing the first and second normalized image data to provide resultant image data, and generating a probability map for the region of interest based on the resultant image data and a predefined statistical model. The probability map indicates the probability of at least a portion of an abnormality being present at locations within the region of interest. |
| FILED | Wednesday, December 05, 2012 |
| APPL NO | 14/362354 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/7264 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 8/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4806 (20130101) G01R 33/5602 (20130101) G01R 33/5608 (20130101) Measurement of Nuclear or X-radiation G01T 1/16 (20130101) Electric Digital Data Processing G06F 19/345 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0016 (20130101) G06T 7/0034 (20130101) G06T 7/0081 (20130101) Original (OR) Class G06T 7/0087 (20130101) G06T 2207/10004 (20130101) G06T 2207/10081 (20130101) G06T 2207/10084 (20130101) G06T 2207/10088 (20130101) G06T 2207/10116 (20130101) G06T 2207/20081 (20130101) G06T 2207/20141 (20130101) G06T 2207/20224 (20130101) G06T 2207/30016 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608547 | Ding et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Xiaoyun Ding (State College, Pennsylvania); Tony Jun Huang (State College, Pennsylvania) |
| ABSTRACT | An apparatus for manipulating particles uses tunable standing surface acoustic waves includes a channel defined on a substrate and a pair of variable frequency interdigital transducers. The channel is disposed asymmetrically between the transducers such that the zero order node location is outside of a working region in the channel. |
| FILED | Thursday, January 31, 2013 |
| APPL NO | 13/755865 |
| ART UNIT | 3653 — Semiconductors/Memory |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0864 (20130101) B01L 2400/0436 (20130101) Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/3427 (20130101) Electric Machines Not Otherwise Provided for H02N 2/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608803 | Alahmadi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Ahmed S. Alahmadi (East Lansing, Michigan); Mai M. Abdelhakim (East Lansing, Michigan); Jian Ren (Okemos, Michigan); Tongtong Li (Okemos, Michigan) |
| ABSTRACT | A method for defense against primary user emulation attacks in cognitive radio networks includes the steps of generating an advanced encryption standard (AES)-encrypted reference signal with a transmitter for transmitting to at least one receiver. The method also includes the steps of allowing a shared secret between the transmitter and the at least one receiver and regenerating the reference signal at the at least one receiver and using the regenerated reference signal to achieve accurate identification of authorized primary users as well as malicious users. |
| FILED | Wednesday, December 03, 2014 |
| APPL NO | 14/558832 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0631 (20130101) Original (OR) Class H04L 9/3228 (20130101) H04L 63/0435 (20130101) Pictorial Communication, e.g Television H04N 21/2351 (20130101) H04N 21/44236 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 09603810 | Amsden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tufts University (Medford, Massachusetts) |
| ASSIGNEE(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
| INVENTOR(S) | Jason J. Amsden (Durham, North Carolina); David L. Kaplan (Concord, Massachusetts); Fiorenzo G. Omenetto (Lexington, Massachusetts) |
| ABSTRACT | The present invention provides for photonic nanoimprinted silk fibroin-based materials and methods for making same, comprising embossing silk fibroin-based films with photonic nanometer scale patterns. In addition, the invention provides for processes by which the silk fibroin-based films can be nanoimprinted at room temperature, by locally decreasing the glass transition temperature of the silk film. Such nanoimprinting process increases high throughput and improves potential for incorporation of silk-based photonics into biomedical and other optical devices. |
| FILED | Wednesday, April 30, 2014 |
| APPL NO | 14/265781 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/70 (20130101) A61K 9/7007 (20130101) Original (OR) Class A61K 41/00 (20130101) A61K 47/42 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/774 (20130101) G01N 21/4788 (20130101) G01N 2021/7776 (20130101) Optical Elements, Systems, or Apparatus G02B 5/1809 (20130101) G02B 5/1847 (20130101) G02B 6/262 (20130101) G02B 6/1225 (20130101) G02B 6/02061 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604087 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher Brown (Bloomington, Indiana); Lawrence Shirley, II (Bloomfield, Indiana) |
| ABSTRACT | Various apparatuses for rope-climbing and associated methods are provided. Embodiments include a circular loop of rope and a variable braking system allowing for a freely suspended rope-climbing experience a safe distance from the ground and at a speed variable to individual users. |
| FILED | Thursday, September 10, 2015 |
| APPL NO | 14/849788 |
| ART UNIT | 3764 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 1/14 (20130101) A62B 35/00 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 7/04 (20130101) Original (OR) Class A63B 29/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604169 | Sebastian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Thomas Sebastian (Waltham, Massachusetts); Timothy Stephens (West Chatham, Massachusetts) |
| ABSTRACT | A discrete bypass particle concentrator can significantly reduce surface fouling and manufacturing cost by including bypass stages after each of concentration stages. |
| FILED | Friday, March 20, 2015 |
| APPL NO | 14/664771 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 45/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/40 (20130101) G01N 1/4077 (20130101) G01N 2015/0046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604301 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YuMing Zhang (Nicholasville, Kentucky); Xiangrong Li (Peabody, Massachusetts); Zeng Shao (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | YuMing Zhang (Nicholasville, Kentucky); Xiangrong Li (Peabody, Massachusetts); Zeng Shao (Lexington, Kentucky) |
| ABSTRACT | The invention discloses a method to determine the weld joint penetration from arc voltage measurements in gas tungsten arc welding (GTAW). It is based on an observation on the dynamic weld pool surface in GTAW—the surface tends to first expand toward the electrode and then be pushed away from the electrode after full penetration is established. For the pool surface in GTAW, localized partial keyholes around the arc axis as in plasma arc welding are not significant. The pool surface is relatively smooth. The arc voltage that reflects changes in the arc length thus first tends to reduce and then increases after full penetration is established. This invention thus tracks the arc voltage until the decrease slope becomes insignificant. Once full penetration is established, the current is reduced to decrease the weld penetration or first decrease the penetration growth for a certain period and then decrease the weld penetration. |
| FILED | Tuesday, November 13, 2012 |
| APPL NO | 13/694231 |
| ART UNIT | 3742 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/09 (20130101) B23K 9/167 (20130101) B23K 9/0282 (20130101) B23K 9/0286 (20130101) B23K 9/0956 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604369 | Angold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ekso Bionics, Inc. (Richmond, California) |
| ASSIGNEE(S) | Ekso Bionics, Inc. (Richmond, California) |
| INVENTOR(S) | Russdon Angold (American Canyon, California); Nicholas Fleming (San Francisco, California) |
| ABSTRACT | An exoskeleton comprises a torso brace, configured to be coupled to a torso of a user, and a leg support, configured to be coupled to a leg of the user. A plurality of links couples the torso brace to the leg support. The plurality of links includes a first link, coupled to the torso brace at a first pivot point, and a second link, coupled to the leg support at a second pivot point. The first link is coupled to the second link through a third pivot point located between the first and second pivot points. The first pivot point enables adduction of the leg support, and the third pivot point enables abduction of the leg support. |
| FILED | Monday, June 01, 2015 |
| APPL NO | 15/023851 |
| ART UNIT | 3782 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0237 (20130101) A61H 1/0244 (20130101) A61H 3/00 (20130101) A61H 2001/0248 (20130101) A61H 2201/149 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1619 (20130101) A61H 2201/1628 (20130101) A61H 2201/1676 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 17/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604712 | Vaganay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bluefin Robotics Corporation (Quincy, Massachusetts) |
| ASSIGNEE(S) | General Dynamics Mission Systems, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Jerome Vaganay (Arlington, Massachusetts); Leo Gurfinkel (Newton, Massachusetts) |
| ABSTRACT | Autonomous, unmanned submersible can turn upside down in order to use instrumentation placed on one side only. Batteries (106) and instrumentation housing (104) are installed on frame rails (112,14,108,110) and can change their relative positions, thus inverting the relative positions between center of buoyancy and center of gravity and subsequently inverting the submersible. |
| FILED | Thursday, May 30, 2013 |
| APPL NO | 14/404395 |
| ART UNIT | 3617 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/14 (20130101) Original (OR) Class B63G 2008/002 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1083 (20130101) H01M 2220/20 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49716 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604736 | Jaeger |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NOVAWURKS, INC. (Los Alamitos, California) |
| ASSIGNEE(S) | NOVAWURKS, INC. (Los Alamitos, California) |
| INVENTOR(S) | Talbot Jaeger (Los Alamitos, California) |
| ABSTRACT | An improved spacecraft actuator wheel is provided which can be operated as a momentum wheel, a reaction wheel or a gimbal. The actuator wheel has a central cavity. One or more battery modules are located within the actuator wheel's central cavity. The battery modules supply power to one or more electronic components affixed to the actuator wheel or mounted on the spacecraft frame via an electrical harness. In addition, the actuator wheel's central cavity is pressurizeable for storing spacecraft propellant which can be controllably diverted to the spacecraft's thrusters through conduits and flow valves. |
| FILED | Thursday, February 12, 2015 |
| APPL NO | 14/620617 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/10 (20130101) B64G 1/44 (20130101) B64G 1/64 (20130101) B64G 1/283 (20130101) B64G 1/285 (20130101) B64G 1/286 (20130101) B64G 1/402 (20130101) B64G 1/425 (20130101) Original (OR) Class B64G 1/428 (20130101) B64G 2001/1092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604737 | Spence et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Deployable Space Systems, Inc. (Goleta, California) |
| ASSIGNEE(S) | Deployable Space Systems, Inc. (Goleta, California) |
| INVENTOR(S) | Brian R Spence (Solvang, California); Stephen F White (Ventura, California) |
| ABSTRACT | A directionally-controlled roll-out elastically deployable solar array structure is disclosed. The structure includes one or more longitudinal elastic roll out booms that may be closed section or open section to allow for efficient rolled packaging onto a lateral mandrel. A flexible photovoltaic blanket is attached to a tip structure and to a lateral base support structure, but remains uncoupled from the longitudinal booms. The solar array system may be stowed simultaneously into a rolled package comprised of the roll out booms and the flexible planar blanket together, or onto independent rolls. Alternatively, the system may be stowed by rolling the booms, and accordion Z-folding the hinged flexible photovoltaic blanket into a flat stack. Structural deployment is motivated by the elastic strain energy of the roll out booms, and several methods of deployment direction control are provided to ensure a known, controlled, and unidirectional deployment path of the elastically unrolling booms. |
| FILED | Wednesday, February 05, 2014 |
| APPL NO | 14/173252 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) B64G 1/443 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/1362 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604923 | Turkson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNIVERSITY OF CENTRAL FLORIDA (Orlando, Florida) |
| ASSIGNEE(S) | H.LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | James Turkson (Honolulu, Hawaii); Said M. Sebti (Tampa, Florida); Wayne Guida (St. Petersburg Beach, Florida); Man Lun Yip (Monrovia, California); Nicholas Lawrence (Tampa, Florida); Harshani Rithma Lawrence (Tampa, Florida); Benjamin Greedy (Somerset, United Kingdom) |
| ABSTRACT | The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S31-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents. |
| FILED | Monday, April 07, 2014 |
| APPL NO | 14/246522 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 235/84 (20130101) C07C 309/73 (20130101) C07C 311/19 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5011 (20130101) G01N 33/5088 (20130101) G01N 33/57407 (20130101) G01N 33/57484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605034 | Stratis-Cullum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Dimitra Nikolaos Stratis-Cullum (Laurel, Maryland); Bryn Lauren Adams (Silver Spring, Maryland); Margaret Mary Hurley (Bel Air, Maryland) |
| ABSTRACT | Provided are compositions are methods for discovery of new materials and interactions under extreme environmental conditions such as elevated temperatures at or in excess of 60° C. A synthetic thermostable protein is provided that is linked to a target peptide. A library of target peptides may be linked to a plurality of the thermostable proteins for expression on the cell surface of a thermophilic organism. The composition employs a modified form of the T. thermophilus TtoA protein that has a non-naturally occurring N-terminus for associating with a target peptide thereby expressing the target peptide on the outer cell membrane where the thermophilic protein is stable at high temperatures for discovery of materials useful in extreme environments or for us in study conditions that require or suffer under elevated temperatures. |
| FILED | Friday, August 28, 2015 |
| APPL NO | 14/838392 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/21 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605057 | Scherer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Philipp Erich Scherer (Southlake, Texas); Jiyoung Park (Dallas, Texas); Zhiqiang An (Pearland, Texas) |
| ABSTRACT | Aspects of the present invention relate to methods and reagents for increasing chemosensitivity to platinum-based chemotherapy. In one aspect, a method of increasing chemosensitivity to platinum-based chemotherapy is provided, comprising administering to a patient in need thereof an effective amount of an endotrophin-neutralizing agent. The agent can be a monoclonal antibody, or fragment thereof, capable of binding to the C5 domain of the alpha3 chain of collagen VI. In some embodiments, the method can further include administering an effective amount of thiazolidinedione to said patient. |
| FILED | Tuesday, June 17, 2014 |
| APPL NO | 14/306784 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 49/0004 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605181 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jue Lu (Okemos, Michigan); Amirpasha Peyvandi (Lansing, Michigan); Saqib Ul Abideen (Lansing, Michigan); Anagi Balachandra (Lansing, Michigan) |
| ASSIGNEE(S) | Metna Co (, None) |
| INVENTOR(S) | Jue Lu (Okemos, Michigan); Amirpasha Peyvandi (Lansing, Michigan); Saqib Ul Abideen (Lansing, Michigan); Anagi Balachandra (Lansing, Michigan) |
| ABSTRACT | The present invention is directed towards an article suitable for attachment to facial skin or other surfaces, which comprises microfibrils and continuous microribbons. The article provides good sealing when used on a regular skin, and on a challenge skin surface with facial hair, sweat and acnes. The article also provides good adhesion and sealing on any other rough surfaces, and can be used repeatedly against different surfaces. These dry adhesives can be used for improving sealing of mask respirators, swimming goggles, or for other applications such as medical bandage, working gloves, and protective clothing seal. |
| FILED | Tuesday, May 13, 2014 |
| APPL NO | 14/275966 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/00 (20130101) Original (OR) Class C09J 2201/626 (20130101) C09J 2400/22 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2481 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605260 | Ecker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IBIS BIOSCIENCES, INC. (Carlsbad, California) |
| ASSIGNEE(S) | IBIS BIOSCIENCES, INC. (Carlsbad, California) |
| INVENTOR(S) | David J. Ecker (Encinitas, California); Todd P. Michael (Carlsbad, California); Lendell L. Cummins (San Diego, California); Mark W. Eshoo (San Diego, California); Stanley T. Motley (Carlsbad, California); Danny M. Chou (Carlsbad, California) |
| ABSTRACT | Provided herein are compositions and methods for the alteration of neuronal methylation by synthetic piRNAs or by alteration of piRNA function. Such alterations find use in the regulation and control of neural gene expression and concomitant neural functions. Further provided herein are systems and methods for the identification of target sites for regulation by piRNAs. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/212412 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/10 (20130101) C12N 2320/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605344 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Ying-Bing Jiang (Albuquerque, New Mexico); Joseph L. Cecchi (Albuquerque, New Mexico); Yaqin Fu (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico) |
| ABSTRACT | An atomic layer deposition method is disclosed for preparing polypeptides. The method comprises providing a solid-phase support comprising a reactive amine monolayer in an atomic layer deposition (ALD) chamber. The solid-phase support is contacted with a first protected amino acid substituted with a protecting group by atomic layer deposition, wherein the protecting group is bonded to a non-side chain amino group of the protected amino acid. A carboxylic acid group of the first protected amino acid is reacted with the reactive amine monolayer, thereby coupling the first protected amino acid to the solid-phase support to produce a coupled-product. |
| FILED | Friday, September 12, 2014 |
| APPL NO | 14/917566 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/46 (20130101) C23C 16/45525 (20130101) Original (OR) Class C23C 16/45534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605359 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Zhenqiang Ma (Middleton, Wisconsin); Jung-Hun Seo (Madison, Wisconsin) |
| ABSTRACT | Boron-doped diamond and methods for making it are provided. The doped diamond is made using an ultra-thin film of heavily boron-doped silicon as a dopant carrying material in a low temperature thermal diffusion doping process. |
| FILED | Tuesday, October 07, 2014 |
| APPL NO | 14/508187 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/04 (20130101) C30B 31/02 (20130101) Original (OR) Class C30B 33/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/041 (20130101) H01L 21/324 (20130101) H01L 29/1602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605363 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Mei Zhang (Tallahassee, Florida); Shaoli Fang (Richardson, Texas); Ray H. Baughman (Dallas, Texas); Anvar A. Zakhidov (McKinney, Texas); Kenneth Ross Atkinson (Victoria, Australia); Ali E. Aliev (Dallas, Texas); Sergey Li (Dallas, Texas); Chris Williams (Dallas, Texas) |
| ABSTRACT | Fabricating a nanofiber ribbon or sheet with a process that includes providing a primary assembly by arranging carbon nanotube nanofibers in aligned arrays, the arrays having a degree of inter-fiber connectivity, drawing the carbon nanotube nanofibers from the primary assembly into a sheet or ribbon, and depositing the sheet or ribbon on a substrate. |
| FILED | Wednesday, November 25, 2015 |
| APPL NO | 14/952179 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0059 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/02 (20130101) B32B 5/12 (20130101) B32B 18/00 (20130101) B32B 37/12 (20130101) B32B 2262/106 (20130101) B32B 2307/202 (20130101) B32B 2310/00 (20130101) B32B 2313/04 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0226 (20130101) C01B 31/0253 (20130101) C01B 31/0293 (20130101) C01B 2202/06 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/62231 (20130101) C04B 35/62272 (20130101) C04B 35/62281 (20130101) C04B 35/62855 (20130101) C04B 35/62892 (20130101) C04B 35/62897 (20130101) C04B 2235/422 (20130101) C04B 2235/526 (20130101) C04B 2235/5248 (20130101) C04B 2235/5264 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/50 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) D01F 9/127 (20130101) D01F 9/1275 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/16 (20130101) D02G 3/28 (20130101) D02G 3/44 (20130101) Original (OR) Class Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 3/002 (20130101) Treating Textile Materials Using Liquids, Gases or Vapours D06B 15/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2001/1515 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0048 (20130101) H01L 51/5206 (20130101) H01L 51/5234 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8605 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Y02E 60/13 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) Y10S 977/745 (20130101) Y10S 977/752 (20130101) Y10S 977/843 (20130101) Y10S 977/847 (20130101) Y10S 977/848 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605540 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL INTERNATIONAL, INC. (Morristown, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| INVENTOR(S) | Frank Lin (Torrance, California); Davis Jensen (Lomita, California); Marshall Saville (Torrance, California); Phil McAfee (Rancho Palos Verdes, California); David G. Elpern (Los Angeles, California) |
| ABSTRACT | A radial inflow turbine may include a wheel, a first set of nozzle vanes surrounding the wheel and a second set of nozzle vanes surrounding the wheel. A first circumferential spacing between two adjacent nozzle vanes of the first set may differ from a second circumferential spacing between another two of the nozzle vanes of the first set. |
| FILED | Tuesday, August 20, 2013 |
| APPL NO | 13/971497 |
| ART UNIT | 3748 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 1/08 (20130101) Original (OR) Class F01D 5/141 (20130101) F01D 5/143 (20130101) F01D 5/145 (20130101) F01D 9/02 (20130101) F01D 9/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/96 (20130101) F05D 2260/961 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605557 | Rolling |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | August J Rolling (Colorado Springs, Colorado) |
| ABSTRACT | A variable bypass turbofan engine includes a bypass fan having a plurality of bypass fan blades mated to a first low pressure shaft segment. A second low pressure shaft segment includes a low pressure compressor and a low pressure turbine mated thereto. The engine also includes a clutch coupled between the first low pressure shaft segment and the second low pressure shaft segment and is configured to selectively couple and decouple the first low pressure shaft segment from the second low pressure shaft segment. A brake is configured to selectively halt or oppose rotation of the first low pressure shaft segment or the bypass fan. |
| FILED | Tuesday, April 01, 2014 |
| APPL NO | 14/231947 |
| ART UNIT | 3748 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/325 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/00 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/36 (20130101) Jet-propulsion Plants F02K 3/02 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605596 | Lefevre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Nicholas Lefevre (Vernon, Connecticut); John J. Korzendorfer (Glastonbury, Connecticut); Peter Balawajder (Vernon, Connecticut); Paul W. Palmer (S. Glastonbury, Connecticut); Paul J. Colucci (Glastonbury, Connecticut); Mahamoud Coulibaly (East Hartford, Connecticut) |
| ABSTRACT | A seal system for a gas turbine engine includes an annular seal carrier and an annular compliant seal mounted around the annular seal carrier, the compliant seal includes a multiple of legs in cross-section. |
| FILED | Wednesday, January 08, 2014 |
| APPL NO | 14/150385 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/075 (20130101) Non-positive-displacement Pumps F04D 19/02 (20130101) F04D 27/0215 (20130101) F04D 29/083 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/90 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605768 | Goldfarb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Michael Goldfarb (Nashville, Tennessee); Xiangrong Shen (Tuscaloosa, Alabama) |
| ABSTRACT | A solenoid valve including a spool received within a housing. The spool is configured to move to multiple positions within the housing. The housing includes supply ports, exhaust ports, and outlet ports. When the spool is in a specific location, two outlet ports are in fluid communication with each other. |
| FILED | Friday, December 20, 2013 |
| APPL NO | 14/135915 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 11/024 (20130101) F15B 13/042 (20130101) F15B 13/0402 (20130101) F15B 2013/0412 (20130101) F15B 2211/3122 (20130101) F15B 2211/3133 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/07 (20130101) F16K 27/041 (20130101) F16K 31/426 (20130101) F16K 31/0613 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/86493 (20150401) Y10T 137/87169 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605953 | Marocchini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Windsor Locks, Connecticut) |
| INVENTOR(S) | Francis P. Marocchini (Somers, Connecticut); Gregory DiVincenzo (Wethersfield, Connecticut); Mike R. Lyon (South Windsor, Connecticut) |
| ABSTRACT | A sensor assembly includes a first structure and a second structure disposed radially outwardly of the first structure. Also included is a sensor body extending through the first and second structures, the sensor body having first and second ends, the second end disposed in an ambient environment. Further included is a first sealing assembly configured to couple the sensor body to the second structure and to accommodate movement of the sensor body due to relative movement between the first and second structures. Yet further included is an interior cavity defined by an interior wall of the sensor body and a rotary position sensor mounted to the sensor body proximate the second end of the sensor body, the rotary position sensor configured to detect an angular position of a target disposed within the first environment, the rotary position sensor coupled to the target with a sensor linkage assembly. |
| FILED | Thursday, October 30, 2014 |
| APPL NO | 14/528515 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/02 (20130101) F01D 21/003 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/22 (20130101) Original (OR) Class Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606009 | Marocchini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Windsor Locks, Connecticut) |
| INVENTOR(S) | Francis P. Marocchini (Somers, Connecticut); Gregory DiVincenzo (Wethersfield, Connecticut); Mike R. Lyon (South Windsor, Connecticut); Raymond Surace (Newington, Connecticut) |
| ABSTRACT | A sensor assembly includes a first structure and a second structure disposed radially outwardly of the first structure. Also included is a sensor body extending through the first and second structures, the sensor body having first and second ends, the first end disposed proximate a first environment defined by the first structure and the second end located radially outwardly of the second structure. Further included is a first sealing assembly configured to operatively couple the sensor body to the second structure and to accommodate movement of the sensor body. Yet further included is a position sensor operatively coupled to the sensor body, the position sensor configured to determine a position of a target located within the first interior volume. Also included is at least one biasing member in contact with the target to bias the target into constant operative contact with the sensor body. |
| FILED | Thursday, October 30, 2014 |
| APPL NO | 14/528416 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/02 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/22 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/00 (20130101) G01D 5/02 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 13/00 (20130101) Original (OR) Class Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606024 | Marocchini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Francis P. Marocchini (Somers, Connecticut); Gregory DiVincenzo (Wethersfield, Connecticut); Mark W. Colebrook (Gastonbury, Connecticut); Mike R. Lyon (South Windsor, Connecticut) |
| ABSTRACT | A sensor assembly includes a first structure and a second structure disposed radially outwardly of the first structure. Also included is a sensor body extending through the first and second structures, the sensor body having first and second ends, the second end disposed in an ambient environment. Further included is a sensor mounted to the sensor body proximate the second end, the sensor configured to detect a characteristic of a target disposed within the first structure. Yet further included is a first sealing assembly configured to operatively couple the sensor body to the second structure and to accommodate movement of the sensor body. The first sealing assembly includes a mounting body, a radial seal, a slider plate and a slider plate retainer disposed in a recess of the mounting body and in abutment with the slider plate. |
| FILED | Thursday, October 30, 2014 |
| APPL NO | 14/528380 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 13/00 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606028 | Detweiller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Carrick Detweiller (Lincoln, Nebraska); John-Paul Ore (Seward, Nebraska); Baoliang Zhao (Lincoln, Nebraska); Sebastian Elbaum (Lincoln, Nebraska) |
| ABSTRACT | In one aspect, a vehicle includes an aerial propulsion system, an altitude sensor system, a water sampling system, and a control system. The water sampling system includes a water sampling extension configured to extend away from the vehicle, one or more water sample receptacles, and a water pump. The control system is configured to perform operations including: guiding, using the aerial propulsion system, the vehicle over a water source; causing, using sensor data from the altitude sensor system, the vehicle to descend towards the water source so that the water sampling extension contacts the water source; and causing, using the water sampling system, the water pump to pump water from the water source into the one or more water sample receptacles through the water sampling extension while the vehicle is in flight over the water source. |
| FILED | Friday, February 13, 2015 |
| APPL NO | 14/621733 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/12 (20130101) B64C 2201/024 (20130101) B64C 2201/141 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/14 (20130101) Original (OR) Class G01N 2001/021 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/08 (20130101) G01S 15/025 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/042 (20130101) G05D 1/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606078 | Patel |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nirmalkumar G. Patel (Jacksonville, Florida) |
| ASSIGNEE(S) | University of North Florida Board of Trustees (Jacksonville, Florida) |
| INVENTOR(S) | Nirmalkumar G. Patel (Jacksonville, Florida) |
| ABSTRACT | A sensor for sensing gaseous chemicals includes a substrate, a variable resistance nanocrystalline ITO thin film formed on the substrate, and electrodes electrically coupled to the thin film. A sensor array assembly includes a sensor slide and a perforated interface circuit. The interface circuit abuts and electrically couples the sensor slide. The sensor slide includes several spaced apart ITO film strips formed on a slide substrate. A common electrode is electrically coupled to a common portion of each ITO film strip providing an electrically conductive path across the common portions of each of the plurality of spaced apart ITO film strips. A discrete electrode is electrically coupled to a discrete portion of each ITO film strip. The interface circuit is configured to abut and electrically couple to the sensor slide. A conductive discrete electrode pad electrically couples each of the plurality of discrete electrodes of the sensor slide to discrete terminals on the interface circuit. A conductive common electrode pad is associated with and electrically couples the common electrode of the sensor slide to a common electrode on the interface circuit. Apertures in the interface circuit expose the thin film to the environment. Resistance changes in a detectible manner upon exposure to sensible chemicals at ambient temperature, such as 1,2,2-Trimethylpropyl methylphosphonofluoridate (soman, GD), O-Ethyl S-(2-isopropylaminoethyl) methylphosphonothiolate (VX), distilled bis(2-chloroethyl) sulfide (mustard, HD), carbonyl chloride, Phosgene (CG) and cyanogen chloride (CK), ozone, carbon monoxide, carbon dioxide, acetylene, propane, ammonia, sulfur dioxide, ethanol, methanol, volatile organic compounds and industrial toxic chemicals. |
| FILED | Sunday, November 11, 2007 |
| APPL NO | 11/938290 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/125 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606082 | Mellors et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Scott Mellors (Carrboro, North Carolina); Erin Anne Redman (Carrboro, North Carolina); John Michael Ramsey (Chapel Hill, North Carolina) |
| ABSTRACT | Methods that allow independently applied pressures to a BGE reservoir and a sample reservoir for pressure-driven injection that can inject a discrete sample plug into a separation channel that does not require voltage applied to the sample reservoir and can allow for in-channel focusing methods to be used. The methods are particularly suitable for use with a mass spectrometer. |
| FILED | Monday, January 04, 2016 |
| APPL NO | 14/987326 |
| ART UNIT | 1759 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 2300/0864 (20130101) B01L 2400/049 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) B01L 2400/0487 (20130101) B01L 2400/0622 (20130101) B01L 2400/0666 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44743 (20130101) Original (OR) Class G01N 27/44791 (20130101) G01N 30/7266 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606087 | Taylor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by The Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| INVENTOR(S) | Oliver-Denzil S. Taylor (Vicksburg, Mississippi); Katie E. Martin (Vicksburg, Mississippi) |
| ABSTRACT | An ultrasonic near-surface inundation testing (UNIT) device includes a soil cell device, a head tank feeding fluid into the soil cell and a reservoir tank feeding fluid into the head tank. The soil cell device includes a substantially planar base, at least one removable top plate with at least one pressure equalization port, at least one bottom plate, at least one sample chamber holding a soil sample, bender ports and a bender sensor pair. The base connects to chamber posts. The top plate connects to the chamber posts and has a cell inlet receiving fluid from the head tank. The bottom plate connects to the chamber posts and has a cell outlet passing fluid to the reservoir tank. The sample chamber, including at least one removable chamber plate, is located between the top and bottom plates. The bender sensor pair extend into the sample chamber through the bender ports. |
| FILED | Thursday, October 22, 2015 |
| APPL NO | 14/920385 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/04 (20130101) Original (OR) Class G01N 33/24 (20130101) G01N 2291/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606167 | Kung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hsiang-Tsung Kung (Belmont, Massachusetts); Dario Vlah (Natick, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Hsiang-Tsung Kung (Belmont, Massachusetts); Dario Vlah (Natick, Massachusetts) |
| ABSTRACT | Circuitry, systems and methods for testing integrated circuits for the presence of anomalies. Techniques include applying a plurality of inputs to an integrated circuit under test to obtain a first plurality of measurements at least partially characterizing power leakage in the integrated circuit under test, encode the first plurality of measurements, by computing a plurality of random linear combinations of measurements in the first plurality of measurements, to obtain a second plurality of encoded measurements determining whether the integrated circuit under test contains at least one anomaly based, at least in part, on the second plurality of encoded measurements. |
| FILED | Thursday, August 02, 2012 |
| APPL NO | 13/565420 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2601 (20130101) Original (OR) Class G01R 31/31719 (20130101) G01R 31/31721 (20130101) G01R 31/31835 (20130101) Electric Digital Data Processing G06F 11/0751 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606414 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | David R. Smith (Durham, North Carolina); Antoine Moreau (Gerzat, France); Cristian Ciraci (Durham, North Carolina); Jack J. Mock (Durham, North Carolina) |
| ABSTRACT | An apparatus is described that selectively absorbs electromagnetic radiation. The apparatus includes a conducting surface, a dielectric layer formed on the conducting surface, and a plurality of conducting particles distributed on the dielectric layer. The dielectric layer can be formed from a material and a thickness selected to yield a specific absorption spectrum. Alternatively, the thickness or dielectric value of the material can change in response to an external stimulus, thereby changing the absorption spectrum. |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 14/394774 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/17 (20130101) Original (OR) Class G02F 1/35 (20130101) G02F 1/0102 (20130101) G02F 1/0128 (20130101) G02F 2001/3505 (20130101) Antennas, i.e Radio Aerials H01Q 17/002 (20130101) H01Q 17/007 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/89 (20130101) Y10S 977/834 (20130101) Y10S 977/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606848 | Wellman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | William H. Wellman (Santa Barbara, California); Eric J. Gudim (Goleta, California); Lee M. Savage (Santa Barbara, California) |
| ABSTRACT | Several types of noise limit the performance of remote sensing systems, e.g., systems that determine the location, color, or shape of remote objects. When noise detected by sensors of the remote sensing systems is known and well estimated, a Kalman filter can converge on an accurate value without noise. However, non-Gaussian noise bursts can cause the Kalman filter to diverge from an accurate value. Current approaches arbitrarily boost noise with fixed additive or multiplicative factors, which slows filter response and often fails to give timely results. Such noise boosts prevent divergence due to badly corrupted measurements. Disclosed embodiments eliminate a subset of noise measurements having the largest errors from a data set of noise measurements and process the remaining data through the Kalman filter. Advantageously, disclosed embodiments enable a Kalman filter to converge on an accurate value without the introduction of noise boost estimates. |
| FILED | Tuesday, March 12, 2013 |
| APPL NO | 13/796707 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/06 (20130101) G01S 5/0221 (20130101) G01S 5/0294 (20130101) G01S 7/285 (20130101) G01S 13/003 (20130101) Electric Digital Data Processing G06F 11/0706 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607003 | Medard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Muriel Medard (Belmont, Massachusetts); Ulric J. Ferner (Cambridge, Massachusetts); Tong Wang (Cambridge, Massachusetts) |
| ABSTRACT | Multi-resolution encoded files are stored on a plurality of disk drives using systematic network coded storage. In some embodiments, the stored files are used to provide video streaming services for users. |
| FILED | Tuesday, August 13, 2013 |
| APPL NO | 13/965721 |
| ART UNIT | 2159 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/302 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 21/2312 (20130101) H04N 21/23439 (20130101) H04N 21/234327 (20130101) H04N 21/234363 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607246 | Jebara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Tony Jebara (New York, New York); Pannagadatta Shivaswamy (San Mateo, California) |
| ABSTRACT | A system, apparatus, method, and computer-readable medium for optimizing classifiers are disclosed. The optimization process can include receiving one or more training examples. The optimization process can further include assigning a loss parameter to each training example. The optimization process can further include optimizing each loss parameter of each training sample based on a sample variance of each training example using a non-linear function. The optimization process can further include estimating a classifier from the one or more weighted training samples. The optimization process can further include assigning a loss parameter to the classifier based on a number of training examples that the classifier correctly classified and a number of training examples that the classifier incorrectly classified. The optimization process can further include adding the weighted classifier to an overall classifier. |
| FILED | Tuesday, July 30, 2013 |
| APPL NO | 13/953813 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Original (OR) Class G06K 9/6257 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607306 | Hieftje et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Gary M. Hieftje (Bloomington, Indiana); Steven J. Ray (Bloomington, Indiana); Kevin P. Pfeuffer (Bloomington, Indiana); Jacob T. Shelley (Stow, Ohio); Norris J. Caldwell (Bloomington, Indiana) |
| ABSTRACT | A method and apparatus for identification of a counterfeit electronic component, subjecting a suspected counterfeit electronic to an analytical method of ambient surface analysis to desorb and ionize compounds directly from a suspected counterfeit electronic surface with no pretreatment, detecting the resultant ions, comparing the identified ions to known standards, and returning a confidence that the suspected counterfeit electronic being analyzed is counterfeit. |
| FILED | Wednesday, March 18, 2015 |
| APPL NO | 14/662109 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Electric Digital Data Processing G06F 19/70 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0185 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607362 | Baron et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| INVENTOR(S) | Dror Baron (Raleigh, North Carolina); Jin Tan (Raleigh, North Carolina); Yanting Ma (Raleigh, North Carolina) |
| ABSTRACT | Various examples of methods and systems are provided for compressive imaging using approximate message passing with denoising. According to an aspect, a method includes applying an approximate message passing (AMP) conversion framework to a plurality of substantially linear measurements for conversion into a plurality of scalar measurements. A denoiser algorithm can be applied to the plurality of scalar measurements to generate a plurality of denoised scalar measurements. Further, a conversion term can be applied to the plurality of denoised scalar measurements for converting the plurality of denoised scalar measurements to a plurality of denoised substantially linear measurements. The plurality of substantially linear measurements can represent two-dimensional or three-dimensional signals. |
| FILED | Friday, May 15, 2015 |
| APPL NO | 14/713788 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/002 (20130101) Original (OR) Class G06T 9/00 (20130101) G06T 2207/20064 (20130101) Coding; Decoding; Code Conversion in General H03M 7/3062 (20130101) Pictorial Communication, e.g Television H04N 19/80 (20141101) H04N 19/85 (20141101) H04N 19/90 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607802 | Bevis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KLA-Tencor Corporation (Milpitas, California) |
| ASSIGNEE(S) | KLA-Tencor Corporation (Milpitas, California) |
| INVENTOR(S) | Christopher F. Bevis (Los Gatos, California) |
| ABSTRACT | One embodiment relates to an apparatus for aberration correction in an electron beam lithography system. An inner electrode surrounds a pattern generating device, and there is at least one outer electrode around the inner electrode. Each of the inner and outer electrodes has a planar surface in a plane of the pattern generating device. Circuitry is configured to apply an inner voltage level to the inner electrode and at least one outer voltage level to the at least one outer electrode. The voltage levels may be set to correct a curvature of field in the electron beam lithography system. Another embodiment relates to an apparatus for aberration correction used in an electron based system, such as an electron beam inspection, or review, or metrology system. Other embodiments, aspects and features are also disclosed. |
| FILED | Thursday, December 11, 2014 |
| APPL NO | 14/567785 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/153 (20130101) Original (OR) Class H01J 37/3007 (20130101) H01J 37/3174 (20130101) H01J 37/3175 (20130101) H01J 2237/303 (20130101) H01J 2237/0435 (20130101) H01J 2237/1534 (20130101) H01J 2237/3175 (20130101) H01J 2237/31774 (20130101) H01J 2237/31788 (20130101) H01J 2237/31789 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607815 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Jae Hyung Lee (Palo Alto, California); Igor Bargatin (Wynnewood, Pennsylvania); Bernard Vancil (Beaverton, Oregon); Roger T. Howe (Los Gatos, California) |
| ABSTRACT | Improved thermionic energy converters are provided by electrodes that include a silicon carbide support structure, a tungsten adhesion layer disposed on the silicon carbide support structure, and an activation layer disposed on the tungsten adhesion layer. The activation layer is a material that lowers the electrode work function, such as BaO, SrO and/or CaO. |
| FILED | Friday, September 12, 2014 |
| APPL NO | 14/485423 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 45/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608146 | Dressick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Walter J. Dressick (Waldorf, Maryland); Jasbinder S. Sanghera (Ashburn, Virginia); Woohong Kim (Lorton, Virginia); Colin C. Baker (Alexandria, Virginia); Jason D. Myers (Alexandria, Virginia); Jesse A. Frantz (Landover, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Walter J. Dressick (Waldorf, Maryland); Jasbinder S. Sanghera (Ashburn, Virginia); Woohong Kim (Lorton, Virginia); Colin C. Baker (Alexandria, Virginia); Jason D. Myers (Alexandria, Virginia); Jesse A. Frantz (Landover, Maryland) |
| ABSTRACT | A composition of matter and method of forming copper indium gallium sulfide (CIGS), copper indium gallium selenide (CIGSe), or copper indium gallium telluride thin film via conversion of layer-by-layer (LbL) assembled Cu—In—Ga oxide (CIGO) nanoparticles and polyelectrolytes. CIGO nanoparticles are created via a flame-spray pyrolysis method using metal nitrate precursors, subsequently coated with polyallylamine (PAH), and dispersed in aqueous solution. Multilayer films are assembled by alternately dipping a substrate into a solution of either polydopamine (PDA) or polystyrenesulfonate (PSS) and then in the CIGO-PAH dispersion to fabricate films as thick as 1-2 microns. After LbL deposition, films are oxidized to remove polymer and sulfurized, selenized, or tellurinized to convert CIGO to CIGS, CIGSe, or copper indium gallium telluride. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 14/682574 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02565 (20130101) H01L 21/02568 (20130101) H01L 21/02601 (20130101) H01L 21/02614 (20130101) H01L 21/02628 (20130101) H01L 31/0322 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608299 | Adams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Douglas E. Adams (West Lafayette, Indiana); James M. Caruthers (Lafayette, Indiana); Farshid Sadeghi (West Lafayette, Indiana); Mark D. Suchomel (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Douglas E. Adams (West Lafayette, Indiana); James M. Caruthers (Lafayette, Indiana); Farshid Sadeghi (West Lafayette, Indiana); Mark D. Suchomel (West Lafayette, Indiana) |
| ABSTRACT | Apparatuses and methods for determining one or more performance related characteristics (such as state of charge and/or health) of one or more electrochemical cells that store and release electrical energy are disclosed. Embodiments include pressure and/or temperature sensors that sense a change in pressure resulting from the tendency of the electrochemical cell to change volume and/or the temperature of the one or more electrochemical cells as the electrochemical cell(s) are charged or discharged. Alternate embodiments include one or more calculating members that receive pressure and/or temperature information from the pressure and/or temperature sensing members and calculate a performance related characteristic of the electrochemical cell. Still further embodiments include determining one or more performance related characteristics of an electrochemical cell by sensing the tendency of an electrochemical cell to change volume (such as by sensing pressure) and/or by sensing the temperature as the electrochemical cell is charged or discharged. |
| FILED | Friday, June 08, 2012 |
| APPL NO | 14/124819 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/345 (20130101) H01M 10/48 (20130101) H01M 10/482 (20130101) H01M 10/486 (20130101) H01M 10/4285 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608323 | Berens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter Stuart Berens (San Diego, California); David Vincent Arney (El Cajon, California); Hale Bradford Simonds (Santee, California); Susan Lynn Morales (San Diego, California); Dennis Bermeo (San Diego, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Peter Stuart Berens (San Diego, California); David Vincent Arney (El Cajon, California); Hale Bradford Simonds (Santee, California); Susan Lynn Morales (San Diego, California); Dennis Bermeo (San Diego, California) |
| ABSTRACT | An omni-directional antenna can include a feed disk, which can terminate at a feed disk apex, and a top element, which can include a nipple that terminates a top element apex. The feed disk and top element can be positioned so that the feed disk apex and the top element apex can be spaced-apart by a distance “d”, which can be chosen according to the desired frequency range and cable feed impedance. The feed disk and top element can also have respective bottom conical and top conical surfaces. When the feed disk and top element are positioned, the top and bottom conical surfaces can establish a respective first predefined angle relative to a horizontal plane and a second predefined angle relative to the horizontal plane, thereby extending the antenna frequency range. The predefined angles can be chosen according to the desired frequency range of operation and cable feed impedance. |
| FILED | Tuesday, October 22, 2013 |
| APPL NO | 14/059520 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/50 (20130101) Original (OR) Class H01Q 13/04 (20130101) H01Q 13/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608406 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oracle International Corporation (Redwood Shores, California) |
| ASSIGNEE(S) | ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California) |
| INVENTOR(S) | Jin-Hyoung Lee (San Diego, California); Xuezhe Zheng (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
| ABSTRACT | An optical source includes a semiconductor optical amplifier that provides an optical signal, and a photonic chip with first and second ring resonators that operate as Vernier rings. When the optical source is operated below a lasing threshold, one or more thermal-tuning mechanisms, which may be thermally coupled to the first ring resonator and/or the second ring resonator, may be adjusted to align resonances of the first ring resonator and the second ring resonator based on measured optical power on a shared optical waveguide that is optically coupled to the first and second ring resonators. Then, when the optical source is operated above the lasing threshold, a common thermal-tuning mechanism may be adjusted to lock the aligned resonances with an optical cavity mode of the optical source based on a measured optical power on an optical waveguide that is optically coupled to the first ring resonator. |
| FILED | Friday, January 22, 2016 |
| APPL NO | 15/004569 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/026 (20130101) H01S 5/0612 (20130101) Original (OR) Class H01S 5/1071 (20130101) H01S 5/3013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608738 | Riedl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Thomas J. Riedl (Urbana, Illinois); Andrew C. Singer (Champaign, Illinois) |
| ABSTRACT | A Doppler compensation system includes a transmitter unit for transmitting a signal, wherein the transmitted signal being associated with an emission time-scale, a receiving unit for receiving a signal, wherein the received signal is associated with a receive time-scale that is not equivalent to the emission time-scale, and a Doppler compensating unit configured to estimate an inverse temporal distortion function, wherein the Doppler compensating unit implements the inverse temporal distortion function to estimate the transmitted signal. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/844543 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/44 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 21/18 (20160201) Transmission H04B 11/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608802 | Yuen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Quantum Advance Technology, Inc. (Glenview, Illinois) |
| ASSIGNEE(S) | Quantum Advance Technology, Inc. (Glenview, Illinois) |
| INVENTOR(S) | Horace P Yuen (Glenview, Illinois) |
| ABSTRACT | A new cryptographic technique is disclosed, called decoy bits method, which can be used to obtain near ideal information theoretic security in both quantum and classical key generation and data encryption, not only for raw security but also under known-plaintext attacks. The technique relates to a method of data encryption by insertion of random bits, called decoy bits, into a data sequence whereby the decoy bits are discarded upon decryption. The positions of the decoy bits are determined by a decoy position determining mechanism. This method can be used in conjunction with other standards of encryption to increase security. |
| FILED | Thursday, March 06, 2014 |
| APPL NO | 14/198924 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/002 (20130101) H04L 9/06 (20130101) Original (OR) Class H04L 9/065 (20130101) H04L 9/0618 (20130101) H04L 9/0656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608817 | Gentry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York); University of Bristol (Bristol, United Kingdom) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Craig B. Gentry (New York, New York); Shai Halevi (Elmsford, New York); Nigel P. Smart (Bristol, United Kingdom) |
| ABSTRACT | Homomorphic evaluation of a function is performed on input ciphertext(s), which were encrypted using a public key of an encryption scheme that also includes multiple secret keys. Each input ciphertext includes multiple real numbers that are kept with finite precision. Performing the homomorphic evaluation of the function includes performing operation(s). Performing each of one or more operations includes the following. A key-switching transformation is performed on selected ciphertext(s), including converting a first version of a selected ciphertext with respect to a first of the secret keys and with some number r bits of precision to a second version of the selected ciphertext with respect to a second of the secret keys and with some other number r′ bits of precision, r′>r. Each key switching transformation is performed prior to or after the operation(s) are evaluated. Results of the operation(s) are output. |
| FILED | Thursday, January 28, 2016 |
| APPL NO | 15/008921 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) H04L 9/08 (20130101) H04L 9/16 (20130101) Original (OR) Class H04L 9/30 (20130101) H04L 9/0618 (20130101) H04L 2209/24 (20130101) H04L 2209/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09609238 | Videen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gorden W. Videen (Silver Spring, Maryland); Kristan P. Gurton (Olney, Maryland); Alexey J. Yuffa (Silver Spring, Maryland) |
| ABSTRACT | A method and apparatus is provided for modeling a three-dimensional topological surface of an object acquiring, using a thermal imaging camera, a first image of the object, wherein the first image comprises a plurality of pixels each representative of at least one component of thermal data, calculating a normal vector for each pixel in the first image, corresponding to the normal vector on a surface of the object, generating a three-dimensional model representing a surface of the object based on aggregating the normal vector for each pixel together in the first image. |
| FILED | Monday, February 09, 2015 |
| APPL NO | 14/617393 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 17/00 (20130101) G06T 2200/08 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09609756 | Call et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Norman L. Call (Los Angeles, California); Jose M. Chavez (Walnut, California); Rodolfo Chavez (West Hills, California) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Norman L. Call (Los Angeles, California); Jose M. Chavez (Walnut, California); Rodolfo Chavez (West Hills, California) |
| ABSTRACT | A method includes aligning a first portion of a magnetic core with respect to a first side of a PCB using a first alignment device. The method includes applying a first bonding material to a surface of at least one of the first portion of the magnetic core and a second portion of the magnetic core. The method further includes coupling a second alignment device that retains the second portion of the magnetic core to the first alignment device. When the first alignment device and the second alignment device are coupled, the first portion and the second portion of the magnetic core are retained in a specified assembly position. The specified assembly position includes a specified gap between the first portion and the second portion of the magnetic core. The method also includes curing the first bonding material. |
| FILED | Wednesday, October 01, 2014 |
| APPL NO | 14/504208 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/007 (20130101) H05K 3/30 (20130101) Original (OR) Class H05K 13/04 (20130101) H05K 2201/086 (20130101) H05K 2201/1003 (20130101) H05K 2203/167 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/5313 (20150115) Y10T 29/49126 (20150115) Y10T 29/53174 (20150115) Y10T 29/53265 (20150115) Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09609791 | Tam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Daniel Wing Shum Tam (San Diego, California); Lu Xu (San Diego, California); Diana Arceo (San Diego, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Wing Shum Tam (San Diego, California); Lu Xu (San Diego, California); Diana Arceo (San Diego, California) |
| ABSTRACT | A method for deploying a lightweight, flexible Faraday cage around a device can include the step of directing the conductive fluid flow in a manner that causes a shroud to form over the device. In some embodiments, a flexible material such as canvas can be deployed over the device and the conductive fluid can be sprayed onto the flexible material to form the shroud. In other embodiments, a plurality of nozzles can be placed around the perimeter of the device, and the nozzles can be directed at a predetermined point over the device. The streams can meet at the predetermined point, collide and thereby provide the conductive shroud for the device. The shroud can have a skin depth, which can be chosen according to the desired frequency of electromagnetic radiation to be blocked, typically from one to one hundred millimeters (1-100 mm). |
| FILED | Wednesday, December 09, 2015 |
| APPL NO | 14/963464 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 9/0001 (20130101) H05K 9/0081 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 09603724 | Geyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hartmut Geyer (Pittsburgh, Pennsylvania); Ruta P. Desai (Pittsburgh, Pennsylvania) |
| ABSTRACT | Local swing leg control was developed that takes advantage of segment interactions to achieve robust leg placement under large disturbances while generating trajectories and joint torque patterns similar to those observed in human walking and running. The results suggest the identified control as a powerful alternative to existing swing leg controls in humanoid and rehabilitation robotics. Alternatively, a detailed neuromuscular model of the human swing leg was developed to embody the control with local muscle reflexes. The resulting reflex control robustly places the swing leg into a wide range of landing points observed in human walking and running, and it generates similar patterns of joint torques and muscle activations. The results suggest an alternative to existing swing leg controls in humanoid and rehabilitation robotics which does not require central processing. |
| FILED | Wednesday, August 27, 2014 |
| APPL NO | 14/470277 |
| ART UNIT | 3738 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/64 (20130101) A61F 2/68 (20130101) A61F 2/605 (20130101) Original (OR) Class A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/762 (20130101) A61F 2002/6827 (20130101) A61F 2002/7625 (20130101) A61F 2002/7645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09603800 — Methods of treating inflammatory and autoimmune diseases and disorders using nanolipogels
| US 09603800 | Fahmy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Michael Look (Seattle, Washington); Joseph Craft (Hamden, Connecticut) |
| ABSTRACT | Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, an absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant. |
| FILED | Friday, April 12, 2013 |
| APPL NO | 14/394147 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 9/1273 (20130101) Original (OR) Class A61K 9/1277 (20130101) A61K 31/343 (20130101) A61K 38/1841 (20130101) A61K 38/2013 (20130101) A61K 47/24 (20130101) A61K 47/40 (20130101) A61K 47/48176 (20130101) A61K 47/48969 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09603945 | DeAngelis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Paul L. DeAngelis (Edmond, Oklahoma) |
| ABSTRACT | Compositions, methods, and systems are disclosed for the development and use of heparosan, a natural polymer related to heparin, as a new therapeutic modifying agent or vehicle which can modulate drug cargo pharmacokinetics and behavior within a mammalian patient. |
| FILED | Friday, December 14, 2012 |
| APPL NO | 13/715117 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/4823 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604269 | Kumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Golden Kumar (Lubbock, Texas); Jan Schroers (Hamden, Connecticut); Jerzy Blawzdziewicz (Lubbock, Texas); Thomas Hodges (North Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Golden Kumar (Lubbock, Texas); Jan Schroers (Hamden, Connecticut); Jerzy Blawzdziewicz (Lubbock, Texas); Thomas Hodges (North Haven, Connecticut) |
| ABSTRACT | A method of processing BMGs in a non-ideal environment (such as air) to create a uniform and smooth surface is provided. By utilizing the contact-line movement and an engineered flow pattern during TPF the method is able to create complex BMG parts that exhibit uniform smooth appearance or even can be atomically smooth. In addition, to mending surface imperfections, this method also eliminates void formation inside the material, allows for the creation of precise patterns of homogeneous appearance, and forms improved mechanical locks between different materials and a BMG. |
| FILED | Friday, July 08, 2011 |
| APPL NO | 13/808969 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Rolling of Metal B21B 27/06 (20130101) Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 23/01 (20130101) Original (OR) Class B21C 29/003 (20130101) B21C 31/00 (20130101) B21C 33/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 37/0053 (20130101) B29C 43/003 (20130101) B29C 43/36 (20130101) B29C 2043/3615 (20130101) B29C 2043/3628 (20130101) Alloys C22C 1/002 (20130101) C22C 45/003 (20130101) C22C 45/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604955 | Guo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ting Guo (Davis, California) |
| ABSTRACT | A method for dynamic enhancement of chemical reactions by nanomaterials under hard X-ray irradiation. The nanomaterials were gold and platinum nanoparticles, and the chemical reaction employed was the hydroxylation of coumarin carboxylic acid. The reaction yield was enhanced 2000 times over that predicted on the basis of the absorption of X-rays only by the nanoparticles, and the enhancement was found for the first time to depend on the X-ray dose rate. The maximum turnover frequency was measured at 1 16×10-4 s-1 Gy-1. We call this process chemical enhancement, which is defined as the increased yield of a chemical reaction due to the chemical properties of the added materials. The chemical enhancement described here is believed to be ubiquitous and may significantly alter the outcome of chemical reactions under X-ray irradiation with the assistance of nanomaterials. |
| FILED | Friday, January 11, 2013 |
| APPL NO | 14/370733 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 311/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605031 | Gelbart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William M. Gelbart (Los Angeles, California); Charles M. Knobler (Los Angeles, California); Rees F. Garmann (Santa Cruz, California); Odisse Azizgolshani (Whittier, California); Ruben D. Cadena-Nava (Ensenada, Mexico) |
| ABSTRACT | The invention provides compositions of matter comprising a cowpea chlorotic mottle virus capsid protein (CCMV CP) and a ribonucleic acid, as well as methods for using such compositions. In such compositions, the cowpea chlorotic mottle virus capsid protein envelops the ribonucleic acid so as to for a capsid that can inhibit the degradation of the ribonucleic acid (e.g. by RNAses). A method of delivering a ribonucleic acid into the cytoplasm of a mammalian cell is also provided. Typically, the method comprises the steps of combining the mammalian cell with a composition of matter described herein under conditions selected to allow the cowpea chlorotic mottle virus capsid to contact the mammalian cell and deliver the ribonucleic acid into the cytoplasm of a mammalian cell. |
| FILED | Thursday, November 13, 2014 |
| APPL NO | 14/540816 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/045 (20130101) C12N 2770/14022 (20130101) C12N 2770/14023 (20130101) C12N 2770/14042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605246 | Haurwitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Rachel E. Haurwitz (Berkeley, California); Jennifer A. Doudna (Berkeley, California); Blake Wiedenheft (Oakland, California); Martin Jinek (Berkeley, California) |
| ABSTRACT | The present disclosure provides variant Csy4 endoribonucleases, nucleic acids encoding the variant Csy4 endoribonucleases, and host cells genetically modified with the nucleic acids. The variant Csy4 endoribonucleases find use in a variety of applications, which are also provided. The present disclosure also provides methods of detecting a specific sequence in a target polyribonucleotide; and methods of regulating production of a target RNA in a eukaryotic cell. |
| FILED | Wednesday, June 10, 2015 |
| APPL NO | 14/735383 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/22 (20130101) C07K 14/8117 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6823 (20130101) C12Q 2521/313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09605253 — Electrokinetic confinement of neurite growth for dynamically configurable neural networks
| US 09605253 | Voldman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Centre National de la Recherche Scientifique (Paris, France) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France) |
| INVENTOR(S) | Joel Voldman (Belmont, Massachusetts); Thibault Honegger (Boston, Massachusetts); David Peyrade (Moirans, France) |
| ABSTRACT | Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance cue. The physical guidance cue may be used to alter the growth of the neurite and may be temporally and spatially dynamic, such that neurite growth may be altered in a spatial and/or temporal manner. Dynamic control of neurite growth may be used to form directional neural connections, intersections, and/or overlaps. |
| FILED | Tuesday, January 14, 2014 |
| APPL NO | 14/154797 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/205 (20130101) A61N 1/326 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/34 (20130101) C12M 35/02 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 13/00 (20130101) Original (OR) Class C12N 2529/00 (20130101) C12N 2533/54 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09605254 — Electrokinetic confinement of neurite growth for dynamically configurable neural networks
| US 09605254 | Voldman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Centre National de la Recherche Scientifique (Paris, France) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France) |
| INVENTOR(S) | Joel Voldman (Belmont, Massachusetts); Thibault Honegger (Boston, Massachusetts); David Peyrade (Moirans, France) |
| ABSTRACT | Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance cue. The physical guidance cue may be used to alter the growth of the neurite and may be temporally and spatially dynamic, such that neurite growth may be altered in a spatial and/or temporal manner. Dynamic control of neurite growth may be used to form directional neural connections, intersections, and/or overlaps. |
| FILED | Tuesday, January 14, 2014 |
| APPL NO | 14/154823 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/205 (20130101) A61N 1/326 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/34 (20130101) C12M 35/02 (20130101) C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 13/00 (20130101) Original (OR) Class C12N 2529/00 (20130101) C12N 2533/54 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605270 | McDonald et al. |
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| FUNDED BY |
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| APPLICANT(S) | Karen A. McDonald (Fairfield, California); Abhaya Dandekar (Davis, California); Bryce W. Falk (Davis, California); Mysore R. Sudarshana (Davis, California); Sandra L. Uratsu (Davis, California); Michael A. Plesha (Davis, California); Ting-Kuo Huang (Davis, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Karen A. McDonald (Fairfield, California); Abhaya Dandekar (Davis, California); Bryce W. Falk (Davis, California); Mysore R. Sudarshana (Davis, California); Sandra L. Uratsu (Davis, California); Michael A. Plesha (Davis, California); Ting-Kuo Huang (Davis, California) |
| ABSTRACT | The invention relates to a novel chemically inducible plant viral amplicon (CMViva) expression system that permits controllable, high level expression of foreign genes in plant hosts. This system employs agro-infiltration of plants to provide a transient production of a protein of interest, such as a human blood protein. This system provides a major advantage over existing plant expression systems because it allows for consistent expression of foreign or heterologous proteins in plant hosts. |
| FILED | Monday, September 24, 2007 |
| APPL NO | 12/442395 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/8125 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8203 (20130101) Original (OR) Class C12N 15/8216 (20130101) C12N 15/8217 (20130101) C12N 15/8238 (20130101) C12N 15/8257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605298 | Craighead et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Harold G. Craighead (Ithaca, New York); Benjamin R. Cipriany (Wappingers Falls, New York); Stephen Levy (Ithaca, New York); Paul Soloway (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Harold G. Craighead (Ithaca, New York); Benjamin R. Cipriany (Wappingers Falls, New York); Stephen Levy (Ithaca, New York); Paul Soloway (Ithaca, New York) |
| ABSTRACT | Systems and methods are provided for high speed sorting of objects in a continuous body of fluid. The object can be analyzed within one or more interrogation volumes that allow for simultaneous or time-correlated measurement of the object's properties. A processor can interpret the properties of the object and then measured and then direct the object to one of a plurality of downstream flow paths. In some embodiments, the sorting of the object is based on two or more properties of the object. The sorting process can be repeated to create a network of sorting events. |
| FILED | Friday, August 06, 2010 |
| APPL NO | 13/389259 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0663 (20130101) B01L 2300/0654 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2561/113 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606028 | Detweiller et al. |
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| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Carrick Detweiller (Lincoln, Nebraska); John-Paul Ore (Seward, Nebraska); Baoliang Zhao (Lincoln, Nebraska); Sebastian Elbaum (Lincoln, Nebraska) |
| ABSTRACT | In one aspect, a vehicle includes an aerial propulsion system, an altitude sensor system, a water sampling system, and a control system. The water sampling system includes a water sampling extension configured to extend away from the vehicle, one or more water sample receptacles, and a water pump. The control system is configured to perform operations including: guiding, using the aerial propulsion system, the vehicle over a water source; causing, using sensor data from the altitude sensor system, the vehicle to descend towards the water source so that the water sampling extension contacts the water source; and causing, using the water sampling system, the water pump to pump water from the water source into the one or more water sample receptacles through the water sampling extension while the vehicle is in flight over the water source. |
| FILED | Friday, February 13, 2015 |
| APPL NO | 14/621733 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/12 (20130101) B64C 2201/024 (20130101) B64C 2201/141 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/14 (20130101) Original (OR) Class G01N 2001/021 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/08 (20130101) G01S 15/025 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/042 (20130101) G05D 1/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606086 | Ding et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Xiaoyun Ding (State College, Pennsylvania); Tony Jun Huang (State College, Pennsylvania) |
| ABSTRACT | An apparatus for manipulating particles within a fluid sample includes a substrate having a substrate surface. A surface acoustic wave (SAW) generator generates a SAW within a SAW region of the substrate surface. The SAW has an SAW direction aligned with a pressure node. A channel is configured to receive the fluid sample and the fluid sample has a flow direction which is at an oblique angle to the SAW direction. |
| FILED | Wednesday, July 31, 2013 |
| APPL NO | 13/955709 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0864 (20130101) B01L 2400/0436 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 29/02 (20130101) Original (OR) Class G01N 29/222 (20130101) G01N 2015/0019 (20130101) G01N 2015/1006 (20130101) G01N 2291/0423 (20130101) G01N 2291/02466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606100 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael Z. Lin (Stanford, California); Francois St-Pierre (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michael Z. Lin (Stanford, California); Francois St-Pierre (Stanford, California) |
| ABSTRACT | Fluorescent protein voltage sensors for measuring membrane potential and imaging high-frequency neuronal electrical activity are disclosed. In particular, the invention relates to engineered protein voltage sensors that comprise a voltage-sensing domain comprising four transmembrane domains linked to a circularly permuted fluorescent protein, which is inserted into the extracellular loop between the third (S3) and fourth (S4) transmembrane segments of the voltage-sensing domain. Such fluorescent protein voltage sensors can be used for measuring the electrical activity of neurons, including single action potentials, trains of action potentials, and subthreshold potential changes and, in particular, for imaging high-frequency neuronal electrical activity. Additionally, fluorescent protein voltage sensors can be used for a variety of other purposes, including measuring the membrane potential of any cell, including other excitable cells such as cardiac cells and endocrine cells, and for screening agents that target ion channels for their effects on membrane potential. |
| FILED | Monday, November 10, 2014 |
| APPL NO | 14/537663 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/705 (20130101) C07K 14/43595 (20130101) C07K 2319/03 (20130101) C07K 2319/033 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/03 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/4833 (20130101) Original (OR) Class G01N 33/6872 (20130101) G01N 2333/916 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606108 | Krishnan et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ramaswamy Krishnan (Cambridge, Massachusetts); Allen Ehrlicher (Boston, Massachusetts); James Butler (Brookline, Massachusetts); David A. Weitz (Bolton, Massachusetts); Jeffrey J. Fredberg (Sharon, Massachusetts); Chan Young Park (Belmont, Massachusetts) |
| ABSTRACT | A platform for biological assays includes a base substrate providing structural support to the platform, at least one surface of the base substrate coated with position markers, a first deformable layer positioned on top of the base substrate, and a second deformable layer positioned on top of the first deformable layer, the second deformable layer embedded with deformation markers. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 14/358891 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/24 (20130101) B32B 2037/243 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/20 (20130101) C12M 25/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) G01N 33/5029 (20130101) Original (OR) Class G01N 2500/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606842 | Kim |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | National Science Foundation (Arlington, Virginia) |
| INVENTOR(S) | Nam Sung Kim (Middleton, Wisconsin) |
| ABSTRACT | A multi-core processor provides circuitry for jointly scaling the number of operating cores and the amount of resources per core in order to maximize processing performance in a power-constrained environment. Such scaling is advantageously provided without the need for scaling voltage and frequency. Selection of the number of operating cores and the amount of resources per core is made by examining the degree of instruction and thread level parallelism available for a given application. Accordingly, performance counters (and other characteristics) implemented in by a processor may be sampled on-line (in real time) and/or performance counters for a given application may be profiled and characterized off-line. As a result, improved processing performance may be achieved despite decreases in core operating voltages and increases in technology process variability over time. |
| FILED | Wednesday, May 08, 2013 |
| APPL NO | 13/889577 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5094 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607017 | Debray et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Saumya K. Debray (Tucson, Arizona); Richard T. Snodgrass (Tucson, Arizona); Rui Zhang (Torrance, California) |
| ABSTRACT | Systems and methods for utilizing relation- and query-specific information to specialize DBMS code at runtime based on identifying runtime locally invariant variables. Runtime invariant is often of the form of variables in code that hold values that are constant during a portion of code execution. Micro-specialization is applied to eliminate from the original program unnecessary code such as branching statements that reference local invariant(s) in branch-condition evaluation. The resulting specialized code reduces the code complexity as well as significantly improves the runtime efficiency during code execution. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 14/368265 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30289 (20130101) Original (OR) Class G06F 17/30321 (20130101) G06F 17/30383 (20130101) G06F 17/30474 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607362 | Baron et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| INVENTOR(S) | Dror Baron (Raleigh, North Carolina); Jin Tan (Raleigh, North Carolina); Yanting Ma (Raleigh, North Carolina) |
| ABSTRACT | Various examples of methods and systems are provided for compressive imaging using approximate message passing with denoising. According to an aspect, a method includes applying an approximate message passing (AMP) conversion framework to a plurality of substantially linear measurements for conversion into a plurality of scalar measurements. A denoiser algorithm can be applied to the plurality of scalar measurements to generate a plurality of denoised scalar measurements. Further, a conversion term can be applied to the plurality of denoised scalar measurements for converting the plurality of denoised scalar measurements to a plurality of denoised substantially linear measurements. The plurality of substantially linear measurements can represent two-dimensional or three-dimensional signals. |
| FILED | Friday, May 15, 2015 |
| APPL NO | 14/713788 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/002 (20130101) Original (OR) Class G06T 9/00 (20130101) G06T 2207/20064 (20130101) Coding; Decoding; Code Conversion in General H03M 7/3062 (20130101) Pictorial Communication, e.g Television H04N 19/80 (20141101) H04N 19/85 (20141101) H04N 19/90 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09607745 | Temnykh |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Alexander Temnykh (Ithaca, New York) |
| ABSTRACT | An undulator with a compact construction is provided that reduces weight, complexity and cost. The compact undulator system and methods provides mechanical integrity without compromising magnetic field quality. |
| FILED | Monday, January 25, 2016 |
| APPL NO | 15/005434 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0008 (20130101) B23K 1/203 (20130101) B23K 35/3601 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/0284 (20130101) Original (OR) Class H01F 41/0253 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0903 (20130101) X-ray Technique H05G 2/00 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/04 (20130101) H05H 2007/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608547 | Ding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Xiaoyun Ding (State College, Pennsylvania); Tony Jun Huang (State College, Pennsylvania) |
| ABSTRACT | An apparatus for manipulating particles uses tunable standing surface acoustic waves includes a channel defined on a substrate and a pair of variable frequency interdigital transducers. The channel is disposed asymmetrically between the transducers such that the zero order node location is outside of a working region in the channel. |
| FILED | Thursday, January 31, 2013 |
| APPL NO | 13/755865 |
| ART UNIT | 3653 — Semiconductors/Memory |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0864 (20130101) B01L 2400/0436 (20130101) Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/3427 (20130101) Electric Machines Not Otherwise Provided for H02N 2/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608803 | Alahmadi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Ahmed S. Alahmadi (East Lansing, Michigan); Mai M. Abdelhakim (East Lansing, Michigan); Jian Ren (Okemos, Michigan); Tongtong Li (Okemos, Michigan) |
| ABSTRACT | A method for defense against primary user emulation attacks in cognitive radio networks includes the steps of generating an advanced encryption standard (AES)-encrypted reference signal with a transmitter for transmitting to at least one receiver. The method also includes the steps of allowing a shared secret between the transmitter and the at least one receiver and regenerating the reference signal at the at least one receiver and using the regenerated reference signal to achieve accurate identification of authorized primary users as well as malicious users. |
| FILED | Wednesday, December 03, 2014 |
| APPL NO | 14/558832 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0631 (20130101) Original (OR) Class H04L 9/3228 (20130101) H04L 63/0435 (20130101) Pictorial Communication, e.g Television H04N 21/2351 (20130101) H04N 21/44236 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09609044 | Reich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joshua Reich (New York, New York); Oren Laadan (New York, New York); Vishal Misra (New York, New York); Eliahu Brosh (New York, New York); Jason Nieh (New York, New York); Daniel Stuart Rubenstein (New York, New York); Alexander Sherman (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Joshua Reich (New York, New York); Oren Laadan (New York, New York); Vishal Misra (New York, New York); Eliahu Brosh (New York, New York); Jason Nieh (New York, New York); Daniel Stuart Rubenstein (New York, New York); Alexander Sherman (New York, New York) |
| ABSTRACT | Methods for distributing and providing access to stored content from remote storage comprising; receiving a first request to access a first portion of stored content from a requestor, wherein the first request is in a file system request format; creating a placeholder for the stored content so that the placeholder has at least one parameter identical to the stored content and the placeholder can hold the first portion of the stored content and at least a second portion of the stored content; requesting the first portion of the stored content from remote storage; receiving the first portion of the stored content from the remote storage; storing the first portion of the stored content in the placeholder; and before the second portion of the stored content has been stored in the placeholder, providing the first portion of the stored content to the requestor using a file system response format. |
| FILED | Monday, November 07, 2011 |
| APPL NO | 13/883558 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 21/632 (20130101) H04N 21/4334 (20130101) H04N 21/8456 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 09604305 | Spicer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | John Patrick Spicer (Plymouth, Michigan); Jeffrey A. Abell (Rochester Hills, Michigan); Michael Anthony Wincek (Rochester, Michigan); Debejyo Chakraborty (Sterling Heights, Michigan); Jennifer Bracey (Holly, Michigan); Hui Wang (Highland, Michigan); Peter W. Tavora (Sterling Heights, Michigan); Jeffrey S. Davis (Grand Blanc, Michigan); Daniel C. Hutchinson (Goodrich, Michigan); Ronald L. Reardon (Fenton, Michigan); Shawn Utz (Washington Township, Michigan) |
| ABSTRACT | A system includes a host machine and a status projector. The host machine is in electrical communication with a collection of sensors and with a welding controller that generates control signals for controlling the welding horn. The host machine is configured to execute a method to thereby process the sensory and control signals, as well as predict a quality status of a weld that is formed using the welding horn, including identifying any suspect welds. The host machine then activates the status projector to illuminate the suspect welds. This may occur directly on the welds using a laser projector, or on a surface of the work piece in proximity to the welds. The system and method may be used in the ultrasonic welding of battery tabs of a multi-cell battery pack in a particular embodiment. The welding horn and welding controller may also be part of the system. |
| FILED | Friday, September 21, 2012 |
| APPL NO | 13/624233 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/10 (20130101) Original (OR) Class B23K 31/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604387 | Dooley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James H. Dooley (Federal Way, Washington); David N. Lanning (Federal Way, Washington) |
| ASSIGNEE(S) | Forest Concepts, LLC (Auburn, Washington) |
| INVENTOR(S) | James H. Dooley (Federal Way, Washington); David N. Lanning (Federal Way, Washington) |
| ABSTRACT | Comminution process of wood veneer to produce wood particles, by feeding wood veneer in a direction of travel substantially normal to grain through a counter rotating pair of intermeshing arrays of cutting discs arrayed axially perpendicular to the direction of wood veneer travel, wherein the cutting discs have a uniform thickness (Td), to produce wood particles characterized by a length dimension (L) substantially equal to the Td and aligned substantially parallel to grain, a width dimension (W) normal to L and aligned cross grain, and a height dimension (H) aligned normal to W and L, wherein the W×H dimensions define a pair of substantially parallel end surfaces with end checking between crosscut fibers. |
| FILED | Friday, October 12, 2012 |
| APPL NO | 13/650400 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Removing Bark or Vestiges of Branches; Splitting Wood; Manufacture of Veneer, Wooden Sticks, Wood Shavings, Wood Fibres or Wood Powder B27L 11/00 (20130101) Original (OR) Class B27L 11/02 (20130101) Fibrous Raw Materials or Their Mechanical Treatment D21B 1/061 (20130101) D21B 1/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604890 | Gunnoe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey); University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Thomas Brent Gunnoe (Palmyra, Virginia); George Fortman (Phoenixville, Pennsylvania); Nicholas C. Boaz (Ewing, New Jersey); John T. Groves (Princeton, New Jersey) |
| ABSTRACT | Embodiments of the present disclosure provide for methods of hydrocarbon functionalization, methods and systems for converting a hydrocarbon into a compound including at least one group ((e.g., hydroxyl group) (e.g., methane to methanol)), functionalized hydrocarbons, and the like. |
| FILED | Thursday, June 26, 2014 |
| APPL NO | 14/900621 |
| ART UNIT | 1672 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/24 (20130101) B01J 2219/24 (20130101) B01J 2219/00051 (20130101) Acyclic or Carbocyclic Compounds C07C 17/00 (20130101) C07C 19/00 (20130101) C07C 29/00 (20130101) Original (OR) Class C07C 29/03 (20130101) C07C 29/147 (20130101) C07C 67/035 (20130101) C07C 67/035 (20130101) C07C 67/035 (20130101) C07C 69/14 (20130101) C07C 69/63 (20130101) C07C 2102/42 (20130101) C07C 2103/74 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605037 | Schnorr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | NOVOZYMES A/S (Bagsvaerd, Denmark); NOVOZYMES, INC. (Davis, California) |
| INVENTOR(S) | Kirk Schnorr (Holte, Denmark); Randall Kramer (Lincoln, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Tuesday, June 14, 2016 |
| APPL NO | 15/182170 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/37 (20130101) Original (OR) Class C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) C12N 9/2434 (20130101) C12N 9/2437 (20130101) C12N 9/2445 (20130101) C12N 15/8246 (20130101) C12N 15/8257 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) Enzymes C12Y 302/01021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605269 | Sillers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Ryan Sillers (Lebanon, New Hampshire); Hans Van Dijken (Schiedam HG, Netherlands); Steve Licht (Utica, New York); Arthur J. Shaw, IV (Grantham, New Hampshire); Alan Benjamin Gilbert (Lebanon, New Hampshire); Aaron Argyros (White River Junction, Vermont); Allan C. Froehlich (Lebanon, New Hampshire); John E. McBride (Lyme, New Hampshire); Haowen Xu (Lebanon, New Hampshire); David A. Hogsett (Lebanon, New Hampshire); Vineet B. Rajgarhia (Lebanon, New Hampshire) |
| ASSIGNEE(S) | Lallemand Hungary Liquidity Management LLC (Budapest, Hungary) |
| INVENTOR(S) | William Ryan Sillers (Lebanon, New Hampshire); Hans Van Dijken (Schiedam HG, Netherlands); Steve Licht (Utica, New York); Arthur J. Shaw, IV (Grantham, New Hampshire); Alan Benjamin Gilbert (Lebanon, New Hampshire); Aaron Argyros (White River Junction, Vermont); Allan C. Froehlich (Lebanon, New Hampshire); John E. McBride (Lyme, New Hampshire); Haowen Xu (Lebanon, New Hampshire); David A. Hogsett (Lebanon, New Hampshire); Vineet B. Rajgarhia (Lebanon, New Hampshire) |
| ABSTRACT | One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce lactate or acetate as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non-native gene encodes a first non-native enzyme involved in the metabolic production of lactate or acetate. Another aspect of the invention relates to a process for converting lignocellulosic biomass to lactate or acetate, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism. |
| FILED | Thursday, May 05, 2011 |
| APPL NO | 13/696207 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/16 (20130101) C12N 1/18 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0067 (20130101) C12N 15/74 (20130101) C12N 15/81 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/02 (20130101) C12P 7/04 (20130101) C12P 7/06 (20130101) C12P 7/10 (20130101) C12P 7/28 (20130101) C12P 7/62 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/01 (20130101) C12R 1/645 (20130101) C12R 1/865 (20130101) Enzymes C12Y 102/01012 (20130101) C12Y 112/99006 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605344 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Ying-Bing Jiang (Albuquerque, New Mexico); Joseph L. Cecchi (Albuquerque, New Mexico); Yaqin Fu (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico) |
| ABSTRACT | An atomic layer deposition method is disclosed for preparing polypeptides. The method comprises providing a solid-phase support comprising a reactive amine monolayer in an atomic layer deposition (ALD) chamber. The solid-phase support is contacted with a first protected amino acid substituted with a protecting group by atomic layer deposition, wherein the protecting group is bonded to a non-side chain amino group of the protected amino acid. A carboxylic acid group of the first protected amino acid is reacted with the reactive amine monolayer, thereby coupling the first protected amino acid to the solid-phase support to produce a coupled-product. |
| FILED | Friday, September 12, 2014 |
| APPL NO | 14/917566 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/46 (20130101) C23C 16/45525 (20130101) Original (OR) Class C23C 16/45534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605565 | Muralidharan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Govindarajan Muralidharan (Knoxville, Tennessee) |
| ABSTRACT | An Fe—Ni—Cr alloy is composed essentially of, in terms of weight percent: 1 to 3.5 Al, up to 2 Co, 15 to 19.5 Cr, up to 2 Cu, 23 to 40 Fe, up to 0.3 Hf, up to 4 Mn, 0.15 to 2 Mo, up to 0.15 Si, up to 1.05 Ta, 2.8 to 4.3 Ti, up to 0.5 W, up to 0.06 Zr, 0.02 to 0.15 C, 0.0001 to 0.007 N, balance Ni, wherein, in terms of atomic percent: 6.5≦Al+Ti+Zr+Hf+Ta≦10, 0.33≦Al÷(Al+Ti+Zr+Hf+Ta)≦0.065, 4≦(Fe+Cr)÷(Al+Ti+Zr+Hf+Ta)≦10, the alloy being essentially free of Nb and V. |
| FILED | Wednesday, June 18, 2014 |
| APPL NO | 14/307733 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 19/056 (20130101) C22C 30/00 (20130101) C22C 30/02 (20130101) Cyclically Operating Valves for Machines or Engines F01L 3/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605644 | Huberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| ASSIGNEE(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| INVENTOR(S) | Garlan J. Huberts (Milford, Michigan); Qiuping Qu (Troy, Michigan); Michael Damian Czekala (Canton, Michigan) |
| ABSTRACT | A dual coil ignition system is provided. The dual coil ignition system includes a first inductive ignition coil including a first primary winding and a first secondary winding, and a second inductive ignition coil including a second primary winding and a second secondary winding, the second secondary winding connected in series to the first secondary winding. The dual coil ignition system further includes a diode network including a first diode and a second diode connected between the first secondary winding and the second secondary winding. |
| FILED | Thursday, June 06, 2013 |
| APPL NO | 13/912073 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines F02P 3/04 (20130101) F02P 3/0453 (20130101) F02P 9/002 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 38/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09607748 — Micro-fabricated integrated coil and magnetic circuit and method of manufacturing thereof
| US 09607748 | Mihailovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Teledyne Scientific and Imaging, LLC (Thousand Oaks, California) |
| ASSIGNEE(S) | Teledyne Scientific and Imaging, LLC (Thousand Oaks, California) |
| INVENTOR(S) | Robert E. Mihailovich (Newbury Park, California); Alex P. Papavasiliou (Thousand Oaks, California); Vivek Mehrotra (Simi Valley, California); Philip A. Stupar (Oxnard, California); Robert L. Borwick, III (Thousand Oaks, California); Rahul Ganguli (Oak Park, California); Jeffrey F. DeNatale (Thousand Oaks, California) |
| ABSTRACT | A micro-fabricated electromagnetic device is provided for on-circuit integration. The electromagnetic device includes a core. The core has a plurality of electrically insulating layers positioned alternatingly between a plurality of magnetic layers to collectively form a continuous laminate having alternating magnetic and electrically insulating layers. The electromagnetic device includes a coil embedded in openings of the semiconductor substrate. An insulating material is positioned in the cavity and between the coil and an inner surface of the core. A method of manufacturing the electromagnetic device includes providing a semiconductor substrate having openings formed therein. Windings of a coil are electroplated and embedded in the openings. The insulating material is coated on or around an exposed surface of the coil. Alternating magnetic layers and electrically insulating layers may be micro-fabricated and electroplated as a single and substantially continuous segment on or around the insulating material. |
| FILED | Wednesday, September 03, 2014 |
| APPL NO | 14/476644 |
| ART UNIT | 2896 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 17/0013 (20130101) Original (OR) Class H01F 2017/0066 (20130101) H01F 2017/0086 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/00 (20130101) H01L 28/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608141 | Gershon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Talia S. Gershon (White Plains, New York); Oki Gunawan (Westwood, New Jersey); Richard A. Haight (Mahopac, New York); Yun Seog Lee (White Plains, New York) |
| ABSTRACT | A photovoltaic device includes a substrate, a back contact comprising a stable low-work function material, a photovoltaic absorber material layer comprising Ag2ZnSn(S,Se)4 (AZTSSe) on a side of the back contact opposite the substrate, wherein the back contact forms an Ohmic contact with the photovoltaic absorber material layer, a buffer layer or Schottky contact layer on a side of the absorber layer opposite the back contact, and a top electrode on a side of the buffer layer opposite the absorber layer. |
| FILED | Monday, December 14, 2015 |
| APPL NO | 14/968252 |
| ART UNIT | 1758 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/07 (20130101) H01L 31/0326 (20130101) H01L 31/1864 (20130101) H01L 31/1884 (20130101) H01L 31/022433 (20130101) H01L 31/022441 (20130101) Original (OR) Class H01L 31/022466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608330 | Singleton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John Singleton (Los Alamos, New Mexico); Lawrence M. Earley (Los Alamos, New Mexico); Frank L. Krawczyk (Santa Fe, New Mexico); James M. Potter (Los Alamos, New Mexico); William P. Romero (Los Alamos, New Mexico); Zhi-Fu Wang (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Laboratory (Los Alamos, New Mexico) |
| INVENTOR(S) | John Singleton (Los Alamos, New Mexico); Lawrence M. Earley (Los Alamos, New Mexico); Frank L. Krawczyk (Santa Fe, New Mexico); James M. Potter (Los Alamos, New Mexico); William P. Romero (Los Alamos, New Mexico); Zhi-Fu Wang (Los Alamos, New Mexico) |
| ABSTRACT | A superluminal antenna element integrates a balun element to better impedance match an input cable or waveguide to a dielectric radiator element, thus preventing stray reflections and consequent undesirable radiation. For example, a dielectric housing material can be used that has a cutout area. A cable can extend into the cutout area. A triangular conductor can function as an impedance transition. An additional cylindrical element functions as a sleeve balun to better impedance match the radiator element to the cable. |
| FILED | Tuesday, February 07, 2012 |
| APPL NO | 13/368200 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/085 (20130101) Antennas, i.e Radio Aerials H01Q 9/0485 (20130101) Original (OR) Class H01Q 21/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09608686 | Coulter |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Joshua Oliver Coulter (Kansas City, Missouri) |
| ABSTRACT | A case for cooling a portable electronic device, the case including a housing and a cartridge. The housing holds the electronic device and has a cartridge compartment for retaining the cartridge. The cartridge includes sets of compartments for retaining substances configured to generate an endothermic reaction when mixed or combined. Pairs of compartments are separated by a divider configured to be selectively breached. The duration of the cooling effect may be extended by periodically breaching dividers of additional compartment pairs. The magnitude of the cooling effect may be increased by breaching multiple compartment pairs at once. The case may also include electronic components for monitoring the temperature of the electronic device and automatically initiating an endothermic reaction when the temperature reaches a predetermined threshold. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 14/957650 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/3888 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE46351 | Apel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | William A. Apel (Jackson, Wyoming); Vicki S. Thompson (Idaho Falls, Idaho) |
| ABSTRACT | A method for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method comprises attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to the antigens in the array to form immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, to form an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity. |
| FILED | Wednesday, February 20, 2013 |
| APPL NO | 13/771915 |
| ART UNIT | 1678 — Electrical Circuits and Systems |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) Original (OR) Class Electric Digital Data Processing G06F 19/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 09604061 | Archer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NeuroPace, Inc. (Mountain View, California) |
| ASSIGNEE(S) | NeuroPace, Inc. (Mountain View, California) |
| INVENTOR(S) | Stephen T. Archer (Sunnyvale, California) |
| ABSTRACT | A current management system for use in the stimulation output stage of a neurostimulation system can be programmed to steer different amounts of current through different stimulation electrodes to vary how strongly the tissue adjacent each electrode is stimulated during a particular programmed stimulation episode. An stimulation electrode drive circuit associated with each electrode that is available for stimulation allows independent control of the flow of current through that electrode. A reference electrode is provided in the circuit to source or sink current as necessary to balance the currents going into and out of the patient, so that no stimulation electrode is required to serve that purpose. More specifically, by configuring the circuit to maintain a constant potential at the reference electrode (e.g., a potential that is approximately half way between a top and bottom voltage rail), the reference electrode will source or sink currents as necessary to cause the net current flow into the patient to be equal to the net current flowing out of the patient, thus satisfying Kirchhoff's current law. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/261822 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36125 (20130101) A61N 1/36157 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604880 | Allouche et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Louisiana Tech University Research Foundation, a division of Louisiana Tech University Foundation, Inc. (Ruston, Louisiana) |
| ASSIGNEE(S) | Louisiana Tech Research Corporation (Ruston, Louisiana) |
| INVENTOR(S) | Erez Allouche (Ruston, Louisiana); Yuri Lvov (Ruston, Louisiana); Carlos Montes (Ruston, Louisiana); Anupam Joshi (Ruston, Louisiana) |
| ABSTRACT | A method of controlling the setting time of a geopolymer by coating aluminosilicate particles with nanoparticles to slow the geopolymerization reaction. The coating effectiveness of the nanoparticles may be enhanced by pretreating the aluminosilicate particles with a layer-by-layer assembly of polyelectrolytes. A geopolymer is formed by mixing about 39% to about 66% by weight aluminosilicate source, about 0% to about 40% by weight sand, about 19% to about 33% by weight of alkali activator solution, and about 1% to about 4% nanoparticles. |
| FILED | Wednesday, August 27, 2014 |
| APPL NO | 14/469687 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 12/00 (20130101) C04B 12/04 (20130101) C04B 14/044 (20130101) C04B 14/106 (20130101) C04B 18/08 (20130101) C04B 18/08 (20130101) C04B 18/101 (20130101) C04B 20/1033 (20130101) C04B 20/1074 (20130101) C04B 20/1074 (20130101) C04B 20/1074 (20130101) C04B 20/1074 (20130101) C04B 22/062 (20130101) C04B 28/006 (20130101) Original (OR) Class C04B 28/006 (20130101) C04B 28/006 (20130101) C04B 40/0633 (20130101) C04B 40/0633 (20130101) C04B 2103/20 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 40/165 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605363 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Mei Zhang (Tallahassee, Florida); Shaoli Fang (Richardson, Texas); Ray H. Baughman (Dallas, Texas); Anvar A. Zakhidov (McKinney, Texas); Kenneth Ross Atkinson (Victoria, Australia); Ali E. Aliev (Dallas, Texas); Sergey Li (Dallas, Texas); Chris Williams (Dallas, Texas) |
| ABSTRACT | Fabricating a nanofiber ribbon or sheet with a process that includes providing a primary assembly by arranging carbon nanotube nanofibers in aligned arrays, the arrays having a degree of inter-fiber connectivity, drawing the carbon nanotube nanofibers from the primary assembly into a sheet or ribbon, and depositing the sheet or ribbon on a substrate. |
| FILED | Wednesday, November 25, 2015 |
| APPL NO | 14/952179 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0059 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/02 (20130101) B32B 5/12 (20130101) B32B 18/00 (20130101) B32B 37/12 (20130101) B32B 2262/106 (20130101) B32B 2307/202 (20130101) B32B 2310/00 (20130101) B32B 2313/04 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0226 (20130101) C01B 31/0253 (20130101) C01B 31/0293 (20130101) C01B 2202/06 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/62231 (20130101) C04B 35/62272 (20130101) C04B 35/62281 (20130101) C04B 35/62855 (20130101) C04B 35/62892 (20130101) C04B 35/62897 (20130101) C04B 2235/422 (20130101) C04B 2235/526 (20130101) C04B 2235/5248 (20130101) C04B 2235/5264 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/50 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) D01F 9/127 (20130101) D01F 9/1275 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/16 (20130101) D02G 3/28 (20130101) D02G 3/44 (20130101) Original (OR) Class Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 3/002 (20130101) Treating Textile Materials Using Liquids, Gases or Vapours D06B 15/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2001/1515 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0048 (20130101) H01L 51/5206 (20130101) H01L 51/5234 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8605 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Y02E 60/13 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) Y10S 977/745 (20130101) Y10S 977/752 (20130101) Y10S 977/843 (20130101) Y10S 977/847 (20130101) Y10S 977/848 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 09604056 | Starr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The United States of America Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Philip A. Starr (Mill Valley, California); Coralie de Hemptinne (San Francisco, California); Jill Ostrem (Greenbrae, California); Nicole Swann (El Cerrito, California) |
| ABSTRACT | The present disclosure provides methods for reducing the clinical presentations of a neurological movement disorder in a subject. Aspects of the methods include measuring cortical local field potentials (LFPs) from the subject's brain, calculating a modulation index related to brain synchronization from the LFPs, and administering deep brain stimulation to the subject if the calculated modulation index is outside of a threshold range. Also provided are devices, systems, and kits that may be used in practicing the subject methods. |
| FILED | Monday, March 21, 2016 |
| APPL NO | 15/076303 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0534 (20130101) A61N 1/36067 (20130101) Original (OR) Class A61N 1/36139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604907 | Longo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Regents of The University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Frank M. Longo (Menlo Park, California); Stephen M. Massa (Burlingame, California) |
| ABSTRACT | Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. |
| FILED | Monday, January 27, 2014 |
| APPL NO | 14/165090 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/401 (20130101) A61K 31/4178 (20130101) A61K 38/185 (20130101) Acyclic or Carbocyclic Compounds C07C 215/68 (20130101) Original (OR) Class Peptides C07K 5/0823 (20130101) C07K 5/1016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604931 | Narayanan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GTx, Inc. (Memphis, Tennessee); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | GTx, Inc. (Memphis, Tennessee); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Ramesh Narayanan (Cordova, Tennessee); James T. Dalton (Upper Arlington, Ohio); Ellis Levin (Long Beach, California) |
| ABSTRACT | The present application relates to methods of treating, preventing, delaying the onset of, reducing the incidence of, or reducing the severity of hypertension and of a condition associated with cardiovascular disease. |
| FILED | Monday, October 15, 2012 |
| APPL NO | 13/652187 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/472 (20130101) Heterocyclic Compounds C07D 217/24 (20130101) Original (OR) Class C07D 217/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 09605771 | Sherrit et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Stewart Sherrit (La Crescenta, California); Mircea Badescu (La Canada Flintridge, California); Xiaoqi Bao (San Gabriel, California); Yoseph Bar-Cohen (Seal Beach, California) |
| ABSTRACT | Apparatus, systems and methods for implementing flow cages and flow cage assemblies in association with high pressure fluid flows and fluid valves are provided. Flow cages and flow assemblies are provided to dissipate the energy of a fluid flow, such as by reducing fluid flow pressure and/or fluid flow velocity. In some embodiments the dissipation of the fluid flow energy is adapted to reduce erosion, such as from high-pressure jet flows, to reduce cavitation, such as by controllably increasing the flow area, and/or to reduce valve noise associated with pressure surge. |
| FILED | Wednesday, June 18, 2014 |
| APPL NO | 14/308374 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/025 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 47/08 (20130101) Original (OR) Class Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 55/0279 (20130101) F16L 55/02718 (20130101) F16L 55/02727 (20130101) F16L 55/02736 (20130101) F16L 55/02781 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/206 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09606219 | Murdock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ronald G. Murdock (Portsmouth, Rhode Island); John D. Mackay (McMurray, Pennsylvania); Douglas A. Cummins (Salem, Connecticut) |
| ASSIGNEE(S) | Progeny Systems Corporation (Manassas, Virginia) |
| INVENTOR(S) | Ronald G. Murdock (Portsmouth, Rhode Island); John D. Mackay (McMurray, Pennsylvania); Douglas A. Cummins (Salem, Connecticut) |
| ABSTRACT | A system for locating an object in a GPS-denied environment includes first and second stationary nodes of a network and an object out of synchronization with a common time base of the network. The system includes one or more processors that are configured to estimate distances between the first stationary node and the object and a distance between the second stationary node and the object by comparing time-stamps of messages relayed between the object and the nodes. A position of the object can then be trilaterated using a location of each of the first and second stationary nodes and the measured distances between the object and each of the first and second stationary nodes. |
| FILED | Monday, August 02, 2010 |
| APPL NO | 12/848903 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/14 (20130101) Original (OR) Class G01S 5/0289 (20130101) G01S 11/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 09604301 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YuMing Zhang (Nicholasville, Kentucky); Xiangrong Li (Peabody, Massachusetts); Zeng Shao (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | YuMing Zhang (Nicholasville, Kentucky); Xiangrong Li (Peabody, Massachusetts); Zeng Shao (Lexington, Kentucky) |
| ABSTRACT | The invention discloses a method to determine the weld joint penetration from arc voltage measurements in gas tungsten arc welding (GTAW). It is based on an observation on the dynamic weld pool surface in GTAW—the surface tends to first expand toward the electrode and then be pushed away from the electrode after full penetration is established. For the pool surface in GTAW, localized partial keyholes around the arc axis as in plasma arc welding are not significant. The pool surface is relatively smooth. The arc voltage that reflects changes in the arc length thus first tends to reduce and then increases after full penetration is established. This invention thus tracks the arc voltage until the decrease slope becomes insignificant. Once full penetration is established, the current is reduced to decrease the weld penetration or first decrease the penetration growth for a certain period and then decrease the weld penetration. |
| FILED | Tuesday, November 13, 2012 |
| APPL NO | 13/694231 |
| ART UNIT | 3742 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/09 (20130101) B23K 9/167 (20130101) B23K 9/0282 (20130101) B23K 9/0286 (20130101) B23K 9/0956 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09605363 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Mei Zhang (Tallahassee, Florida); Shaoli Fang (Richardson, Texas); Ray H. Baughman (Dallas, Texas); Anvar A. Zakhidov (McKinney, Texas); Kenneth Ross Atkinson (Victoria, Australia); Ali E. Aliev (Dallas, Texas); Sergey Li (Dallas, Texas); Chris Williams (Dallas, Texas) |
| ABSTRACT | Fabricating a nanofiber ribbon or sheet with a process that includes providing a primary assembly by arranging carbon nanotube nanofibers in aligned arrays, the arrays having a degree of inter-fiber connectivity, drawing the carbon nanotube nanofibers from the primary assembly into a sheet or ribbon, and depositing the sheet or ribbon on a substrate. |
| FILED | Wednesday, November 25, 2015 |
| APPL NO | 14/952179 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0059 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/02 (20130101) B32B 5/12 (20130101) B32B 18/00 (20130101) B32B 37/12 (20130101) B32B 2262/106 (20130101) B32B 2307/202 (20130101) B32B 2310/00 (20130101) B32B 2313/04 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0226 (20130101) C01B 31/0253 (20130101) C01B 31/0293 (20130101) C01B 2202/06 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/62231 (20130101) C04B 35/62272 (20130101) C04B 35/62281 (20130101) C04B 35/62855 (20130101) C04B 35/62892 (20130101) C04B 35/62897 (20130101) C04B 2235/422 (20130101) C04B 2235/526 (20130101) C04B 2235/5248 (20130101) C04B 2235/5264 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/50 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) D01F 9/127 (20130101) D01F 9/1275 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/16 (20130101) D02G 3/28 (20130101) D02G 3/44 (20130101) Original (OR) Class Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 3/002 (20130101) Treating Textile Materials Using Liquids, Gases or Vapours D06B 15/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2001/1515 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0048 (20130101) H01L 51/5206 (20130101) H01L 51/5234 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8605 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Y02E 60/13 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) Y10S 977/745 (20130101) Y10S 977/752 (20130101) Y10S 977/843 (20130101) Y10S 977/847 (20130101) Y10S 977/848 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 09603988 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vital Access Corporation (Salt Lake City, Utah) |
| ASSIGNEE(S) | Vital Access Corporation (Salt Lake City, Utah) |
| INVENTOR(S) | Nathaniel P. Young (Salt Lake City, Utah); Trent J. Perry (Kaysville, Utah); Duane D. Blatter (Salt Lake City, Utah); Christopher M. Phillips (Salt Lake City, Utah); Mark A. Crawford (Sandy, Utah); G. Doug Smith (Sandy, Utah); Steven Johnson (Lehi, Utah) |
| ABSTRACT | Ports for accessing vessels within a patient include passageways that can guide needles or other access devices directly into the vessels. The ports can be implanted subcutaneously within a patient. Some ports may be used in the creation and use of vascular access buttonholes. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 13/723763 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 17/3423 (20130101) A61B 2017/00641 (20130101) A61B 2017/00654 (20130101) A61B 2017/3425 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/14 (20130101) A61M 1/3653 (20130101) Original (OR) Class A61M 1/3659 (20140204) A61M 1/3661 (20140204) A61M 39/0208 (20130101) A61M 2039/0223 (20130101) A61M 2039/0226 (20130101) A61M 2039/0238 (20130101) A61M 2205/0238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09604387 | Dooley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James H. Dooley (Federal Way, Washington); David N. Lanning (Federal Way, Washington) |
| ASSIGNEE(S) | Forest Concepts, LLC (Auburn, Washington) |
| INVENTOR(S) | James H. Dooley (Federal Way, Washington); David N. Lanning (Federal Way, Washington) |
| ABSTRACT | Comminution process of wood veneer to produce wood particles, by feeding wood veneer in a direction of travel substantially normal to grain through a counter rotating pair of intermeshing arrays of cutting discs arrayed axially perpendicular to the direction of wood veneer travel, wherein the cutting discs have a uniform thickness (Td), to produce wood particles characterized by a length dimension (L) substantially equal to the Td and aligned substantially parallel to grain, a width dimension (W) normal to L and aligned cross grain, and a height dimension (H) aligned normal to W and L, wherein the W×H dimensions define a pair of substantially parallel end surfaces with end checking between crosscut fibers. |
| FILED | Friday, October 12, 2012 |
| APPL NO | 13/650400 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Removing Bark or Vestiges of Branches; Splitting Wood; Manufacture of Veneer, Wooden Sticks, Wood Shavings, Wood Fibres or Wood Powder B27L 11/00 (20130101) Original (OR) Class B27L 11/02 (20130101) Fibrous Raw Materials or Their Mechanical Treatment D21B 1/061 (20130101) D21B 1/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 09606028 | Detweiller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Carrick Detweiller (Lincoln, Nebraska); John-Paul Ore (Seward, Nebraska); Baoliang Zhao (Lincoln, Nebraska); Sebastian Elbaum (Lincoln, Nebraska) |
| ABSTRACT | In one aspect, a vehicle includes an aerial propulsion system, an altitude sensor system, a water sampling system, and a control system. The water sampling system includes a water sampling extension configured to extend away from the vehicle, one or more water sample receptacles, and a water pump. The control system is configured to perform operations including: guiding, using the aerial propulsion system, the vehicle over a water source; causing, using sensor data from the altitude sensor system, the vehicle to descend towards the water source so that the water sampling extension contacts the water source; and causing, using the water sampling system, the water pump to pump water from the water source into the one or more water sample receptacles through the water sampling extension while the vehicle is in flight over the water source. |
| FILED | Friday, February 13, 2015 |
| APPL NO | 14/621733 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/12 (20130101) B64C 2201/024 (20130101) B64C 2201/141 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/14 (20130101) Original (OR) Class G01N 2001/021 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/08 (20130101) G01S 15/025 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/042 (20130101) G05D 1/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 09607246 | Jebara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Tony Jebara (New York, New York); Pannagadatta Shivaswamy (San Mateo, California) |
| ABSTRACT | A system, apparatus, method, and computer-readable medium for optimizing classifiers are disclosed. The optimization process can include receiving one or more training examples. The optimization process can further include assigning a loss parameter to each training example. The optimization process can further include optimizing each loss parameter of each training sample based on a sample variance of each training example using a non-linear function. The optimization process can further include estimating a classifier from the one or more weighted training samples. The optimization process can further include assigning a loss parameter to the classifier based on a number of training examples that the classifier correctly classified and a number of training examples that the classifier incorrectly classified. The optimization process can further include adding the weighted classifier to an overall classifier. |
| FILED | Tuesday, July 30, 2013 |
| APPL NO | 13/953813 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Original (OR) Class G06K 9/6257 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 09607282 | Brosius, III |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SkyBitz, Inc. (Herndon, Virginia) |
| ASSIGNEE(S) | SkyBitz, Inc. (Herndon, Virginia) |
| INVENTOR(S) | John W. Brosius, III (Frederick, Maryland) |
| ABSTRACT | A multi-mode asset tracking and monitoring system and method is provided that enables comprehensive reporting of asset position, status, and alerts. In one embodiment, the multi-mode system and method is based on the addition of a local network monitoring system to a wide area satellite network monitoring system. In this example, the local network monitoring system would add container presence and status monitoring in crowded environments (e.g., within a port facility, on-board a ship, etc.), while the wide area satellite network monitoring system would provide tracking and monitoring coverage when the container is in dispersed environments. Both the local and wide area monitoring systems work together to provide end-to-end container tracking and monitoring to thereby ensure continuous container tracking and monitoring from container loading to container unloading. |
| FILED | Friday, January 17, 2014 |
| APPL NO | 14/158195 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/08 (20130101) G06Q 10/0833 (20130101) Original (OR) Class G06Q 50/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 09604072 | Brezinski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Donna J. Brezinski (Winchester, Massachusetts) |
| ASSIGNEE(S) | LITTLE SPARROWS TECHNOLOGIES LLC (Winchester, Massachusetts) |
| INVENTOR(S) | Donna J. Brezinski (Winchester, Massachusetts) |
| ABSTRACT | Disclosed is a portable phototherapy device capable of emitting electromagnetic radiation of a wavelength and intensity sufficient to obtain a desired phototherapeutic effect to a subject, without being in direct physical contact with said subject. The device is portable, capable of being flattened, folded, rolled, compressed, or otherwise collapsed, to a size smaller than that of its operating size. The device may be of any size or shape, and may optionally comprise a frame support. The device may be powered by a variety of sources, including one or more batteries. The device may be configured to deliver electromagnetic radiation sufficient to obtain one or more of a variety of desired phototherapeutic effects. |
| FILED | Tuesday, March 12, 2013 |
| APPL NO | 13/794891 |
| ART UNIT | 3769 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/06 (20130101) Original (OR) Class A61N 5/0614 (20130101) A61N 5/0618 (20130101) A61N 5/0621 (20130101) A61N 5/0624 (20130101) A61N 2005/0652 (20130101) A61N 2005/0662 (20130101) A61N 2005/0665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 09604301 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YuMing Zhang (Nicholasville, Kentucky); Xiangrong Li (Peabody, Massachusetts); Zeng Shao (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | YuMing Zhang (Nicholasville, Kentucky); Xiangrong Li (Peabody, Massachusetts); Zeng Shao (Lexington, Kentucky) |
| ABSTRACT | The invention discloses a method to determine the weld joint penetration from arc voltage measurements in gas tungsten arc welding (GTAW). It is based on an observation on the dynamic weld pool surface in GTAW—the surface tends to first expand toward the electrode and then be pushed away from the electrode after full penetration is established. For the pool surface in GTAW, localized partial keyholes around the arc axis as in plasma arc welding are not significant. The pool surface is relatively smooth. The arc voltage that reflects changes in the arc length thus first tends to reduce and then increases after full penetration is established. This invention thus tracks the arc voltage until the decrease slope becomes insignificant. Once full penetration is established, the current is reduced to decrease the weld penetration or first decrease the penetration growth for a certain period and then decrease the weld penetration. |
| FILED | Tuesday, November 13, 2012 |
| APPL NO | 13/694231 |
| ART UNIT | 3742 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/09 (20130101) B23K 9/167 (20130101) B23K 9/0282 (20130101) B23K 9/0286 (20130101) B23K 9/0956 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
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APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20170328.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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