FedInvent™ Patents

Patent Details for Tuesday, May 23, 2017 

This page was updated on Monday, March 27, 2023 at 05:13 AM GMT

Department of Health and Human Services (HHS) 

US 09655512 Huang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) David Huang (Portland, Oregon);  Yan Li (Portland, Oregon);  Ou Tan (Portland, Oregon);  Maolong Tang (Portland, Oregon)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) David Huang (Portland, Oregon);  Yan Li (Portland, Oregon);  Ou Tan (Portland, Oregon);  Maolong Tang (Portland, Oregon)
ABSTRACT This invention discloses methods and systems for measuring corneal epithelial thickness and power, stromal thickness, subepitheila corneal power and topography. The systems and methods disclosed herein are non-invasive, non-contact and automated imaging methods which preferably makes use of Fourier-domain optical tomography. Also disclosed herein are scanning patterns and image analysis methods for utilizing and analyzing Fourier-domain optical coherence tomography images to obtain information about conical epithelial and stromal properties as well as parameters useful for evaluating the properties. The methods and systems described herein are useful as eye disease diagnostic tools and eye surgery planning tools.
FILED Friday, April 06, 2012
APPL NO 13/441733
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/1005 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/60 (20130101)
G06T 2207/10101 (20130101)
G06T 2207/30041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655521 Iftimia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Physical Sciences, Inc. (Andover, Massachusetts)
ASSIGNEE(S) Physical Sciences, Inc. (Andover, Massachusetts);  Memorial Sloan-Kettering Cancer Center (New York, New York)
INVENTOR(S) Nicusor V. Iftimia (Chelmsford, Massachusetts);  Mircea Mujat (Acton, Massachusetts);  R. Daniel Ferguson (Melrose, Massachusetts);  Ankit H. Patel (Methuen, Massachusetts);  Milind Rajadhyaksha (New York, New York)
ABSTRACT A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path.
FILED Thursday, January 31, 2013
APPL NO 13/755741
ART UNIT 3737 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655522 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Debiao Li (South Pasadena, California);  Behzad Sharif (Los Angeles, California);  Daniel S. Berman (Los Angeles, California);  Jianing Pang (Beverly Hills, California)
ABSTRACT The present invention teaches systems and methods for a simple cardiac MRI approach that (1) continuously acquires data; (2) covers the entire heart with high isotropic resolution within a few minutes; and (3) requires no physiological gating and minimal user intervention. Applications of the inventive systems and methods include, but are in no way limited to cardiac cine, myocardial perfusion, coronary MRA, delayed enhancement imaging, myocardial T1-weighted imaging for fibrosis imaging, and myocardial T2-weighted imaging for edema imaging.
FILED Thursday, October 08, 2015
APPL NO 14/878937
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0044 (20130101) Original (OR) Class
A61B 5/055 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4826 (20130101)
G01R 33/4838 (20130101)
G01R 33/5602 (20130101)
G01R 33/5608 (20130101)
G01R 33/5611 (20130101)
G01R 33/5635 (20130101)
G01R 33/56325 (20130101)
G01R 33/56366 (20130101)
G01R 33/56509 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/52 (20130101)

Image Data Processing or Generation, in General
G06T 7/337 (20170101)
G06T 2207/10016 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/30048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655523 Hillman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Non-Profit Organization (NPO)
Wallace H Coulter Foundation (WHCF)
APPLICANT(S) Elizabeth Marjorie Clare Hillman (New York, New York);  Sean A. Burgess (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Elizabeth Marjorie Clare Hillman (New York, New York);  Sean A. Burgess (New York, New York)
ABSTRACT Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).
FILED Tuesday, December 29, 2009
APPL NO 12/655325
ART UNIT 3737 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0064 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0071 (20130101)
A61B 5/0073 (20130101)
A61B 5/0075 (20130101)
A61B 5/0088 (20130101)
A61B 5/444 (20130101)
A61B 5/445 (20130101)
A61B 2562/0238 (20130101)
A61B 2562/0242 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101)
G01J 3/457 (20130101)
G01J 3/2889 (20130101)

Optical Elements, Systems, or Apparatus
G02B 23/2476 (20130101)
G02B 26/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655527 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Lihong Wang (Creve Coeur, Missouri);  Zijian Guo (St. Louis, Missouri)
ABSTRACT Accurately quantifying optical absorption coefficient using acoustic spectra of photoacoustic signals. Optical absorption is closely associated with many physiological parameters, such as the concentration and oxygen saturation of hemoglobin, and it can be used to quantify the concentrations of non-fluorescent molecules. A sample is illuminated by, for example, a pulsed laser and following the absorption of optical energy, a photoacoustic pressure is generated via thermo-elastic expansion. The acoustic waves then propagate and are detected by a transducer. The optical absorption coefficient of the sample is quantified from spectra of the measured photoacoustic signals. Factors, such as system bandwidth and acoustic attenuation, may affect the quantification but are canceled by dividing the acoustic spectra measured at multiple optical wavelengths.
FILED Thursday, June 11, 2015
APPL NO 14/736768
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0095 (20130101) Original (OR) Class
A61B 5/417 (20130101)
A61B 5/7257 (20130101)
A61B 5/14542 (20130101)
A61B 5/14546 (20130101)
A61B 8/13 (20130101)
A61B 8/5215 (20130101)
A61B 2576/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/1702 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655535 Narayan et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Topera, Inc. (Menlo Park, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Topera, Inc. (Menlo Park, California);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Sanjiv Narayan (La Jolla, California);  Carey Robert Briggs (La Jolla, California)
ABSTRACT A system and method to target a biological rhythm disorder, such as a heart rhythm disorder include processing cardiac signals via a computing device to determine a shape in a region of tissue defined by a source associated with the biological rhythm disorder that migrates spatially on or within the shape, and identifying at least one portion of the tissue proximate to the shape to enable selective modification of the at least one portion of tissue in order to terminate or alter the heart rhythm disorder.
FILED Thursday, February 18, 2016
APPL NO 15/047266
ART UNIT 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/042 (20130101)
A61B 5/046 (20130101)
A61B 5/0464 (20130101)
A61B 5/04012 (20130101) Original (OR) Class
A61B 5/4029 (20130101)
A61B 5/4064 (20130101)
A61B 5/4839 (20130101)
A61B 18/1492 (20130101)
A61B 2018/00357 (20130101)
A61B 2018/00577 (20130101)
A61B 2018/00839 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655545 Ji et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Songbai Ji (Lebanon, New Hampshire);  David W. Roberts (Lyme, New Hampshire);  Keith D. Paulsen (Hanover, New Hampshire)
ABSTRACT An apparatus and method for measuring mechanical properties of tissue has a stereo optical surgical microscope with at least one objective lens and at least two digital cameras such that paired images obtained from the digital cameras form stereo pairs, and a digital image processing system adapted to determine surface topography of tissue from the stereo pairs of images and a resulting surface displacement map as a result from indentation. The apparatus has an one indenter; and mechanical modeling routines stored in memory of the image processing system, the mechanical modeling routines capable of constructing computer models of mechanical properties of tissue, and fitting parameters of the computer model to observed surface displacement maps generated by coregistering surface topography of tissue with and without the indenter positioned on the tissue. In an embodiment, fitted parameters of the computer model are displayed and used to adjust a surgical plan. An apparatus and method for measuring mechanical properties of tissue has a stereo optical surgical microscope with at least one objective lens and at least two digital cameras such that paired images obtained from the digital cameras form stereo pairs, and a digital image processing system adapted to determine surface topography of tissue from the stereo pairs of images and a resulting surface displacement map as a result from indentation. The apparatus has an one indenter; and mechanical modeling routines stored in memory of the image processing system, the mechanical modeling routines capable of constructing computer models of mechanical properties of tissue, and fitting parameters of the computer model to observed surface displacement maps generated by coregistering surface topography of tissue with and without the indenter positioned on the tissue. In an embodiment, fitted parameters of the computer model are displayed and used to adjust a surgical plan.
FILED Monday, September 17, 2012
APPL NO 14/345029
ART UNIT 3768 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0053 (20130101)
A61B 5/0077 (20130101)
A61B 5/1079 (20130101) Original (OR) Class
A61B 90/20 (20160201)
A61B 2090/364 (20160201)
A61B 2090/371 (20160201)

Optical Elements, Systems, or Apparatus
G02B 21/0012 (20130101)
G02B 21/367 (20130101)

Image Data Processing or Generation, in General
G06T 7/344 (20170101)
G06T 2200/04 (20130101)
G06T 2207/10012 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/30016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655595 Glossop et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Arcitrax Inc. (Toronto, Canada);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) Arcitrax Inc. (Ontario, Canada);  The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Neil Glossop (Toronto, Canada);  Bradford Wood (North Bethesda, Maryland)
ABSTRACT Methods, systems, and devices for assisting or performing an image-guided prostate procedure are disclosed. A needle assembly includes a needle guide, a needle device, a position sensor and additional features. The position sensor allows for the tracking of the needle assembly. A method for performing image-guided prostate procedures includes pre-operative procedures and intra-operative procedures. The pre-operative procedures include imaging studies to model the prostate and identify targets. The pre-operative procedures models are used during a prostate procedure to track the target and the devices used for the procedure. A system for performing image-guided procedures includes the needle assembly and other components.
FILED Friday, June 14, 2013
APPL NO 13/918413
ART UNIT 3768 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/066 (20130101)
A61B 5/4887 (20130101)
A61B 10/0241 (20130101) Original (OR) Class
A61B 10/0275 (20130101)
A61B 17/3403 (20130101)
A61B 34/20 (20160201)
A61B 90/37 (20160201)
A61B 2017/00092 (20130101)
A61B 2017/00274 (20130101)
A61B 2017/3413 (20130101)
A61B 2034/2051 (20160201)
A61B 2090/365 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655679 Desai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION (College Park, Maryland)
ASSIGNEE(S) University of Maryland (College Park, Maryland)
INVENTOR(S) Jaydev P. Desai (Bethesda, Maryland);  Elif Ayvali (College Park, Maryland)
ABSTRACT A steerable probe having high-power-density actuators positioned at joints along the length of the probe. The actuators are moveable about and between a straight position and a curved position in response to selective actuation.
FILED Wednesday, May 01, 2013
APPL NO 13/875204
ART UNIT 3779 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/3417 (20130101)
A61B 17/3421 (20130101)
A61B 19/201 (20130101) Original (OR) Class
A61B 90/11 (20160201)
A61B 90/39 (20160201)
A61B 2017/003 (20130101)
A61B 2017/00867 (20130101)
A61B 2034/2055 (20160201)
A61B 2090/3735 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655720 Bluestein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York);  THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York);  The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Danny Bluestein (Melville, New York);  Thomas E. Claiborne (Bayport, New York);  Marvin J. Slepian (Tucson, Arizona)
ABSTRACT A polymeric valve which may include a heart valve, and also may include a trileaflet heart valve includes a stent having a base and a plurality of outwardly extending posts from the base and equidistant from each other. A plurality of leaflets each connected to a corresponding one of the posts at one end, and each of the leaflets connected to the base. Each of the leaflets having an operative end opposite the end connected to the post, and the operative ends of the leaflets being biased in a closed position such that the operative ends abut each other. The operative ends are configured to rhythmically open and close in relation to each other, and the leaflets include multiple cross sectional thicknesses at different portions of the leaflets.
FILED Friday, October 12, 2012
APPL NO 14/351455
ART UNIT 3738 — Optics
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/2412 (20130101)
A61F 2/2415 (20130101) Original (OR) Class
A61F 2/2418 (20130101)
A61F 2250/0036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655774 Tai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) California Institute of Technology (Pasadena, California);  University of Southern California (Los Angeles, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California);  University of Southern California (Los Angeles, California)
INVENTOR(S) Yu-Chong Tai (Pasadena, California);  Nicholas Scianmarello (Pasadena, California);  Dongyang Kang (Pasadena, California);  Jungwook Park (Pasadena, California);  Mark S. Humayun (Glendale, California);  Karthik Murali (Los Angeles, California);  Amir H. Kashani (Pasadena, California);  Hossein Nazari Khanamiri (South Pasadena, California)
ABSTRACT A medical device having a permeable bag connected by a non-permeable cannula to a discharge sac is described along with a manufacturing process and surgical implantation method. The permeable portions of the device have pores that are sized to be permeable to a predetermined class of small molecules, such as oxygen, nitrous oxide, or other therapeutic agents. Once absorbed inside the device, the small molecules are then passively transported, by a concentration gradient of the small molecules, to the discharge sac to be disbursed. A metal tube or other strip can be included in the cannula to assist a surgeon in orienting the device within the body.
FILED Friday, June 19, 2015
APPL NO 14/744439
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/0017 (20130101) Original (OR) Class
A61F 2240/001 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 39/10 (20130101)
B29C 41/36 (20130101)
B29C 65/02 (20130101)
B29C 66/54 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/919 (20130101)
B29C 66/949 (20130101)
B29C 66/1142 (20130101)
B29C 66/3242 (20130101)
B29C 66/73754 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2083/005 (20130101)
B29K 2083/005 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/7548 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655815 Xiang et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Rong Xiang (San Diego, California);  He Zhou (San Diego, California);  Ralph A Reisfeld (La Jolla, California)
ABSTRACT A DNA vaccine suitable for eliciting an immune response against cancer cells comprises a DNA construct operably encoding a cancer-associated Inhibitor of Apoptosis-family protein and an immunoactive gene product, such as a cytokine or a ligand for a natural killer cell surface receptor, in a pharmaceutically acceptable carrier. A preferred cytokine is CCL21. Preferred ligands for a natural killer cell surface receptor include human MICA, human MICB, human ULBP1, human ULBP2, and human ULBP3. The cancer-associated Inhibitor of Apoptosis (IAP)-family protein is preferably a survivin protein or livin protein. Method of inhibiting tumor growth by administering the vaccine of the invention to a mammal is also described.
FILED Monday, May 05, 2014
APPL NO 14/269998
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle
A61J 1/05 (20130101) Original (OR) Class

Preparations for Medical, Dental, or Toilet Purposes
A61K 6/00 (20130101)
A61K 39/0011 (20130101)
A61K 2039/53 (20130101)
A61K 2039/523 (20130101)
A61K 2039/55516 (20130101)
A61K 2039/55522 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655839 Fagerberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Marcelle Matos Nascimento Fagerberg (Gainesville, Florida);  Robert A. Burne (Gainesville, Florida)
ABSTRACT The present disclosure provides probiotic arginolytic oral compositions, methods of making probiotic arginolytic oral compositions, and methods of using probiotic arginolytic oral compositions to increase arginolytic activity in the oral cavity and/or to treat and/or prevent caries.
FILED Wednesday, February 12, 2014
APPL NO 14/767181
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 8/99 (20130101) Original (OR) Class
A61K 31/198 (20130101)
A61K 31/7004 (20130101)
A61K 35/741 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 11/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/14 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/315 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655882 Zack et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Donald J. Zack (Baltimore, Maryland);  Zhiyong Yang (Baltimore, Maryland);  Cynthia Berlinicke (Baltimore, Maryland);  Harry Quigley (Baltimore, Maryland)
ABSTRACT Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
FILED Thursday, February 19, 2015
APPL NO 14/626524
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/404 (20130101) Original (OR) Class
A61K 31/404 (20130101)
A61K 31/496 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655914 Cheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Jin Q. Cheng (Tampa, Florida);  Said M. Sebti (Tampa, Florida)
ABSTRACT This application relates to combination therapies including triciribine compounds and epidermal growth factor receptor inhibitor compounds, particularly erlotinib-like compounds and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.
FILED Monday, December 28, 2015
APPL NO 14/998352
ART UNIT 1673 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 31/517 (20130101)
A61K 31/5377 (20130101)
A61K 31/7064 (20130101) Original (OR) Class
A61K 31/7076 (20130101)
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655950 Geskin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Larisa Geskin (Pittsburgh, Pennsylvania);  Oleg E. Akilov (Pittsburgh, Pennsylvania)
ABSTRACT The present invention relates to methods and materials for more effectively treating patients with interferon. It is based on the discovery that clinical response to interferon (IFN) therapy is mediated in part by inhibition of activation of MDSC and such inhibition can be observed after a test dose of interferon; a significant decrease of reactive oxygen species (ROS) production by MDSC (as a measure of their activation) after IFN therapy is predictive of overall response to immunotherapy in cancer patients.
FILED Thursday, November 06, 2014
APPL NO 14/535198
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/212 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/84 (20130101)
G01N 33/5011 (20130101)
G01N 33/57407 (20130101)
G01N 2333/90 (20130101)
G01N 2333/978 (20130101)
G01N 2333/4706 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655952 Lanza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S) Gregory M. Lanza (St. Louis, Missouri);  Dipanjan Pan (St. Louis, Missouri);  Allan Doctor (St. Louis, Missouri);  Philip C. Spinella (St. Louis, Missouri)
ABSTRACT The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
FILED Tuesday, August 09, 2016
APPL NO 15/232298
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0026 (20130101)
A61K 9/51 (20130101)
A61K 9/107 (20130101)
A61K 38/42 (20130101) Original (OR) Class
A61K 38/42 (20130101)
A61K 38/063 (20130101)
A61K 38/063 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655953 Muro Galindo et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Icahn School of Medicine at Mount Sinai (New York, New York);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) Icahn School of Medicine at Mount Sinai (New York, New York);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Silvia Muro Galindo (Silver Spring, Maryland);  Vladimir R. Muzykantov (Bryn Athyn, Pennsylvania);  Edward Howard Schuchman (Haworth, New Jersey)
ABSTRACT The present invention relates to compositions and methods for delivering lysosomal proteins. The compositions and methods described herein permit the targeted delivery of exogenous lysosomal proteins to cell surface proteins that allow their internalization via non-clathrin pathways. The present invention further relates to the use of the compositions and methods for enzyme replacement therapy of lysosomal storage diseases. Nucleic acids, recombinant cells and kits useful for making and using the compositions of the invention are also provided.
FILED Thursday, October 16, 2014
APPL NO 14/516231
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/465 (20130101) Original (OR) Class
A61K 47/48561 (20130101)

Peptides
C07K 16/2821 (20130101)
C07K 2317/77 (20130101)
C07K 2319/035 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)

Enzymes
C12Y 301/04012 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2982 (20150115)
Y10T 428/2991 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655963 Suzuki et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE UAB RESEARCH FOUNDATION (Birmingham, Alabama);  US ARMY WALTER REED ARMY MEDICAL CENTER, CHIEF, OFFICE OF RESEARCH, MARKETING and POLICY DEV (Washington, District of Columbia);  JUNTENDO UNIVERSITY SCHOOL OF MEDICINE, DIVISION OF NEPHROLOGY, DEPARTMENT OF INTERNAL MEDICINE (Tokyo, Japan);  UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama);  US Army Walter Reed Army Medical Center, Chief, Office Of Research, Marketing and Policy Dev Walter Reed Army Institute of Research (Washington, District of Columbia);  Juntendo University School of Medicine, Division of Nephrology, Department of Internal Medicine (Tokyo, Japan);  University of Tennessee Research Foundation (Memphis, Tennessee)
INVENTOR(S) Hitoshi Suzuki (Hoover, Alabama);  Run Fan (Omaha, Nebraska);  Bruce A. Julian (Birmingham, Alabama);  Jan Novak (Pelham, Alabama);  Zina Moldoveanu (Birmingham, Alabama);  Zhixin Zhang (Omaha, Nebraska);  Milan Tomana (Birmingham, Alabama);  Jiri Mestecky (Birmingham, Alabama);  Robert J. Wyatt (Memphis, Tennessee);  Yasuhiko Tomino (Tokyo, Japan);  Yusuke Suzuki (Tokyo, Japan);  Stephen Olson (Rockville, Maryland);  Matthew B. Renfrow (Birmingham, Alabama)
ABSTRACT Provided are methods of diagnosing IgA nephropathy in a subject. Optionally, the methods comprise isolating an IgG from the subject and determining whether the IgG binds to a galactose-deficient IgA1. Optionally, the methods comprise providing a biological sample from the subject and detecting in the sample a mutation in a IGH gene, wherein the mutation is in a nucleotide sequence encoding a complementarity determining region 3 (CDR3) of a IGH variable region. Optionally, the methods comprise determining a level of IgG specific for a galactose-deficient IgA1 in the subject. Also provided are methods of treating or reducing the risk of developing IgA nephropathy in a subject.
FILED Friday, June 27, 2014
APPL NO 14/318082
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39541 (20130101) Original (OR) Class

Peptides
C07K 16/4283 (20130101)
C07K 2317/41 (20130101)
C07K 2317/55 (20130101)
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6854 (20130101)
G01N 33/6893 (20130101)
G01N 2800/347 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655973 Mann
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Vascular Biosciences (San Diego, California)
ASSIGNEE(S) Vascular Biosciences (San Diego, California)
INVENTOR(S) David M. Mann (San Diego, California)
ABSTRACT Disclosed are compositions and methods useful for oral delivery of targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. The disclosed targeting is useful for oral delivery of therapeutic and detectable agents to diseased tissue in an animal.
FILED Monday, March 11, 2013
APPL NO 14/383818
ART UNIT 1676 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/506 (20130101)
A61K 31/519 (20130101)
A61K 38/00 (20130101)
A61K 45/06 (20130101)
A61K 47/42 (20130101) Original (OR) Class
A61K 47/48238 (20130101)

Peptides
C07K 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655993 Kaplan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Tissue Engineering Resource Center (TERC)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) David L. Kaplan (Concord, Massachusetts);  Fiorenzo Omenetto (Wakefield, Massachusetts);  Jeffrey K. Marchant (Littleton, Massachusetts);  Noorjahan Panjwani (Medford, Massachusetts);  Brian Lawrence (Minneapolis, Minnesota)
ABSTRACT This invention relates to a lamellae tissue layer, comprising a grooved silk fibroin substrate comprising tissue-specific cells. The silk fibroin substrates provides an excellent means of controlling and culturing cell and extracellular matrix development. A multitude of lamellae tissue layers can be used to create a tissue-engineered organ, such as a tissue-engineered cornea. The tissue-engineered organ is non-immunogenic and biocompatible.
FILED Tuesday, July 07, 2015
APPL NO 14/793464
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/56 (20130101)
A61L 27/225 (20130101)
A61L 27/227 (20130101)
A61L 27/3604 (20130101) Original (OR) Class
A61L 27/3804 (20130101)
A61L 27/3839 (20130101)
A61L 27/3891 (20130101)
A61L 2300/412 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0621 (20130101)
C12N 2533/50 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656059 Greenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Second Sight Medical Products, Inc. (San Fernando, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Robert J Greenberg (Los Angeles, California);  David D Zhou (Saugus, California);  Jordan Matthew Neysmith (Pasadena, California);  Kelly H McClure (Simi Valley, California);  Jianing Wei (Valencia, California);  Neil H Talbot (La Crecenta, California);  James S Little (Newhall, California)
ABSTRACT A cochlear stimulation device comprising an electrode array designed to provide enhanced charge injection capacity necessary for neural stimulation. The electrode array comprises electrodes with high surface area or a fractal geometry and correspondingly high electrode capacitance and low electrical impedance. The resultant electrodes have a robust surface and sufficient mechanical strength to withstand physical stress vital for long term stability. The device further comprises wire traces having a multilayer structure which provides a reduced width for the conducting part of the electrode array. The cochlear prosthesis is attached by a grommet to the cochleostomy that is made from a single piece of biocompatible polymer. The device, designed to achieve optimum neural stimulation by appropriate electrode design, is a significant improvement over commercially available hand-built devices.
FILED Friday, October 17, 2014
APPL NO 14/517638
ART UNIT 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0472 (20130101)
A61N 1/0541 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656066 Nuccitelli et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Pulse Biosciences, Inc. (Burlingame, California)
ASSIGNEE(S) PULSE BIOSCIENCES, INC. (Burlingame, California)
INVENTOR(S) Richard Lee Nuccitelli (Millbrae, California);  Pamela Nuccitelli (Millbrae, California);  Joanne Lum (San Francisco, California);  Kaying Lui (Millbrae, California);  Brian Athos (San Francisco, California);  Mark Kreis (San Francisco, California);  Zachary Mallon (San Francisco, California);  Jon Berridge (Oakland, California)
ABSTRACT Nanosecond pulsed electric field (nsPEF) treatments of a tumor are adjusted based on size and type of a tumor to stimulate an immune response against the tumor and other tumors in a subject. Calreticulin expression on tumor cells can be detected to confirm treatment. An immune response biomarker can be measured, and further nsPEF treatments can be performed if needed to stimulate or further stimulate the immune response. Cancers that have metastasized may be treated by directly treating a tumor that is most accessible. The treatment can be combined with CD47-blocking antibodies, doxorubicin, CTLA-4-blocking antibodies, and/or PD-1-blocking antibodies. Electrical characteristics of nsPEF treatments can be based on the size, type, and/or strength of tumors and/or a quantity of tumors in the subject.
FILED Wednesday, July 22, 2015
APPL NO 14/805828
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/1477 (20130101)
A61B 2018/0016 (20130101)
A61B 2018/00613 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/05 (20130101)
A61N 1/32 (20130101)
A61N 1/36 (20130101) Original (OR) Class
A61N 1/40 (20130101)
A61N 1/327 (20130101)
A61N 1/0412 (20130101)
A61N 1/0424 (20130101)
A61N 1/37229 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 35/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101)
C12N 15/87 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656069 Danilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Yuri P. Danilov (Middleton, Wisconsin);  Mitchell E. Tyler (Madison, Wisconsin);  Kurt A. Kaczmarek (Madison, Wisconsin)
ASSIGNEE(S)
INVENTOR(S) Yuri P. Danilov (Middleton, Wisconsin);  Mitchell E. Tyler (Madison, Wisconsin);  Kurt A. Kaczmarek (Madison, Wisconsin)
ABSTRACT A method to provide non-invasive neurostimulation to enhance a subject's proficiency in an exercise includes: (a) engaging a subject in an exercise, the subject having no cognitive, physical or emotional impairment with respect to the exercise; (b) providing stimulation of at least one of the subject's trigeminal nerve, facial nerve or hypoglossal nerve by delivering electrical pulses generated by a signal generator to the subject's skin via at least one electrode in contact with the subject's skin, the delivery of electrical pulses being (i) contemporaneously with and independent of the subject's engagement in the exercise, and (ii) independent of the subject's surrounding environment; and (c) repeating steps (a) and (b) on a periodic basis.
FILED Monday, July 11, 2016
APPL NO 15/207029
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0456 (20130101)
A61N 1/0476 (20130101)
A61N 1/0548 (20130101)
A61N 1/36014 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656078 Danilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Yuri P. Danilov (Middleton, Wisconsin);  Mitchell E. Tyler (Madison, Wisconsin);  Kurt A. Kaczmarek (Madison, Wisconsin)
ASSIGNEE(S)
INVENTOR(S) Yuri P. Danilov (Middleton, Wisconsin);  Mitchell E. Tyler (Madison, Wisconsin);  Kurt A. Kaczmarek (Madison, Wisconsin)
ABSTRACT In a patient suffering from neural impairment, stimulation is provided to sensory surfaces of the face and/or neck, or more generally to areas of the body that stimulate the trigeminal nerve, while performing an activity intended to stimulate a brain function to be rehabilitated. The simulation may then be continued after the performance of the activity has ceased. It has been found that the patient's performance of the activity is then improved after stimulation has ceased. Moreover, it tends to improve to a greater extent, and/or for a longer time, when the post-activity stimulation is applied, as compared to when post activity stimulation is not applied.
FILED Friday, February 06, 2015
APPL NO 14/615766
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/361 (20130101)
A61N 1/0548 (20130101)
A61N 1/36067 (20130101)
A61N 1/36078 (20130101)
A61N 1/36092 (20130101)
A61N 1/36096 (20130101)
A61N 1/36103 (20130101) Original (OR) Class

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656293 Kuan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Aaron T. Kuan (Cambridge, Massachusetts);  Jene A. Golovchenko (Lexington, Massachusetts)
ABSTRACT In a method for forming nanopores, two opposing surfaces of a membrane are exposed to an electrically conducting liquid environment. A nanopore nucleation voltage pulse, having a first nucleation pulse amplitude and duration, is applied between the two membrane surfaces, through the liquid environment. After applying the nanopore nucleation voltage pulse, the electrical conductance of the membrane is measured and compared to a first prespecified electrical conductance. Then at least one additional nanopore nucleation voltage pulse is applied between the two membrane surfaces, through the liquid environment, if the measured electrical conductance is no greater than the first prespecified electrical conductance. At least one nanopore diameter tuning voltage pulse, having a tuning pulse voltage amplitude and duration, is applied between the two membrane surfaces, through the liquid environment, if the measured electrical conductance is greater than the first prespecified electrical conductance and no greater than a second prespecified electrical conductance.
FILED Friday, March 14, 2014
APPL NO 14/213243
ART UNIT 1754 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Separation
B01D 67/0034 (20130101)
B01D 67/0062 (20130101)
B01D 67/0065 (20130101)
B01D 69/02 (20130101)
B01D 2323/35 (20130101)
B01D 2325/02 (20130101)

Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/34 (20130101) Original (OR) Class

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/00 (20130101)
C25F 3/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656953 Sebti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Said M. Sebti (Tampa, Florida);  Srikumar Chellappan (Tampa, Florida);  Nicholas James Lawrence (Tampa, Florida)
ABSTRACT The disclosed modulators of Rb:Raf-1 interactions are potent, selective disruptors of Rb:Raf-1 binding, with IC50 values ranging from 80 nM to 500 nM. Further, these compounds are surprisingly effective in inhibiting a wide variety of cancer cells, including osteosarcoma, epithelial lung carcinoma, non-small cell lung carcinoma, three different pancreatic cancer cell lines, two different glioblastoma cell lines, metastatic breast cancer, melanoma, and prostate cancer. Moreover, the disclosed compounds effectively disrupt angiogenesis and significantly inhibited tumors in nude mice derived from human epithelial lung carcinoma tumors. Accordingly, the disclosed compounds, pharmaceutical compositions comprising the compounds, methods of inhibiting cell proliferation, methods of treating subjects with cancer, and methods of preparing the disclosed compounds are provided.
FILED Monday, February 03, 2014
APPL NO 14/171273
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 279/06 (20130101)
C07C 323/45 (20130101) Original (OR) Class
C07C 335/32 (20130101)

Heterocyclic Compounds
C07D 213/53 (20130101)
C07D 215/12 (20130101)
C07D 233/30 (20130101)
C07D 233/84 (20130101)
C07D 235/28 (20130101)
C07D 249/12 (20130101)
C07D 249/14 (20130101)
C07D 277/40 (20130101)
C07D 277/42 (20130101)
C07D 317/56 (20130101)
C07D 317/58 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656981 Spigelman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Igor Spigelman (Los Angeles, California);  Herbert H. Seltzman (Raleigh, North Carolina);  Craig Shiner (Durham, North Carolina)
ABSTRACT Peripherally acting cannabinoid agonist compounds, pharmaceutical compositions, and methods of using them are presented.
FILED Friday, July 19, 2013
APPL NO 14/416026
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 13/465 (20130101)
C07C 39/04 (20130101)
C07C 43/215 (20130101)
C07C 49/788 (20130101)

Heterocyclic Compounds
C07D 209/08 (20130101)
C07D 209/12 (20130101)
C07D 215/12 (20130101)
C07D 215/14 (20130101)
C07D 217/02 (20130101)
C07D 295/03 (20130101)
C07D 295/037 (20130101)
C07D 295/073 (20130101)
C07D 295/096 (20130101)
C07D 307/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656994 Bannister et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Thomas D. Bannister (Palm Beach Gardens, Florida);  Claes R. Wahlestedt (Palm Beach, Florida);  Yen Ting Chen (Palm Beach Gardens, Florida);  Shaun P. Brothers (Port St. Lucie, Florida);  Hasib Salah-Uddin (Jupiter, Florida);  Xiaohong Pan (Palm Beach Gardens, Florida)
ABSTRACT The invention provides modulators of the nociceptin receptor (NOP), including both agonists and antagonists. A compound of the invention can be a selective modulator of NOP with respect to the μ- and κ-opioid receptors (MOP and KOP), thus providing a therapeutic method for the treatment of conditions wherein selective NOP modulation is medically indicated and MOP or KOP modulation may be less desirable. A compound of the invention can be a NOP full agonist, partial agonist, inverse agonist, positive or negative allosteric modulator, or a functionally biased agonist. A compound of the invention can be used for the treatment of an anxiety state, post-traumatic stress disorder, addictive disorders (including overuse of alcohol, tobacco, and drugs of abuse such as cocaine, amphetamines, and opitates), misregulated food intake and/or energy expenditure, cough, sleep disorders, migraine, pain, depression, or neurodegenerative disorders such as Parkinsons disease or Alzheimers disease.
FILED Friday, March 21, 2014
APPL NO 14/779191
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/04 (20130101)
C07D 401/14 (20130101) Original (OR) Class
C07D 405/14 (20130101)
C07D 417/14 (20130101)
C07D 451/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657013 Cuconati et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Baruch S. Blumberg Institute (Doylestown, Pennsylvania);  Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Baruch S. Blumberg Institute (Doylestown, Pennsylvania);  Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Andrea Cuconati (Oreland, Pennsylvania);  Haitao Guo (Lansdale, Pennsylvania);  Timothy M. Block (Doylestown, Pennsylvania);  Ju-Tao Guo (Lansdale, Pennsylvania);  Xiaodong Xu (Doylestown, Pennsylvania);  Huagang Lu (Plainsboro, New Jersey);  Dawei Cai (Doylestown, Pennsylvania)
ABSTRACT Pharmaceutical compositions of the invention comprise covalently closed circular DNA formation inhibitors having a disease-modifying action in the treatment of diseases associated with the formation of covalently closed circular DNA that include hepatitis B infection, and any disease involving formation of covalently closed circular DNA.
FILED Thursday, February 28, 2013
APPL NO 14/382074
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/445 (20130101)
A61K 31/505 (20130101)
A61K 31/4409 (20130101)
A61K 31/4465 (20130101)

Acyclic or Carbocyclic Compounds
C07C 311/21 (20130101)
C07C 317/32 (20130101)

Heterocyclic Compounds
C07D 209/08 (20130101)
C07D 211/26 (20130101)
C07D 211/34 (20130101)
C07D 211/60 (20130101)
C07D 213/40 (20130101)
C07D 213/56 (20130101)
C07D 213/76 (20130101)
C07D 235/08 (20130101)
C07D 239/26 (20130101)
C07D 263/56 (20130101)
C07D 277/64 (20130101)
C07D 295/135 (20130101)
C07D 295/155 (20130101)
C07D 401/12 (20130101)
C07D 471/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657046 Umetsu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Dale T. Umetsu (Newton, Massachusetts);  Rosemarie H. De Kruyff (Newton, Massachusetts);  Ya-Jen Chang (Brookline, Massachusetts);  Petr Illarionov (Birmingham, United Kingdom)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts);  University of Birmingham (Birmingham, United Kingdom)
INVENTOR(S) Dale T. Umetsu (Newton, Massachusetts);  Rosemarie H. De Kruyff (Newton, Massachusetts);  Ya-Jen Chang (Brookline, Massachusetts);  Petr Illarionov (Birmingham, United Kingdom)
ABSTRACT The inventors demonstrate that treatment of young, suckling mice with a glycolipid derived from Helicobacter pylori activates NKT cells in a CD1d-restricted fashion, and is protective against AHR in a model of allergen-induced asthma. The inventors further found that this protective effect can be transferred by NKT cells exposed to the glycolipid, and is associated with the expansion of a suppressive double-negative NKT cells and Foxp3+ TReg cells. The inventors also demonstrate herein that pre-treatment of adult mice with a glycolipid derived from Helicobacter pylori partially suppresses airway hyperreactivity and inhibits BAL inflammation in an ozone-exposure model. Accordingly, provided herein are compositions and methods for the treatment and prevention of inflammatory diseases, such as asthma or autoimmune diseases, in a subject in need thereof.
FILED Tuesday, May 24, 2011
APPL NO 13/699436
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/56 (20130101)
A61K 31/70 (20130101)
A61K 31/704 (20130101)
A61K 35/15 (20130101)
A61K 35/15 (20130101)
A61K 35/17 (20130101)
A61K 35/17 (20130101)
A61K 2039/572 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 15/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657053 Thacher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) ORPHAGEN PHARMACEUTICALS (San Diego, California)
ASSIGNEE(S) ORPHAGEN PHARMACEUTICALS (San Diego, California)
INVENTOR(S) Scott Thacher (San Diego, California);  Xiaolin Li (San Diego, California);  Robert Babine (Carlsbad, California);  Bruno Tse (San Francisco, California)
ABSTRACT Methods for modulating (inhibiting or stimulating) retinoid-related orphan receptor γ (RORγ) activity. This modulation has numerous effects, including inhibition of TH-17 cell function and/or TH-17 cell activity, and inhibition of re-stimulation of TH-17 cells, which are beneficial to treatment of inflammation and autoimmune disorders. Stimulation of RORγ results in stimulation of TH-17 cell function and/or activity which is beneficial for immune-enhancing compositions (e.g., vaccines).
FILED Wednesday, February 13, 2013
APPL NO 13/766076
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/58 (20130101)

Acyclic or Carbocyclic Compounds
C07C 311/21 (20130101)

Heterocyclic Compounds
C07D 249/12 (20130101)
C07D 401/14 (20130101)
C07D 493/10 (20130101)

Steroids
C07J 9/00 (20130101)
C07J 9/005 (20130101) Original (OR) Class
C07J 21/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657060 Carroll et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Michael C. Carroll (Wellesley, Massachusetts);  Francis D. Moore (Medfield, Massachusetts);  Herbert B. Hechtman (Chestnut Hill, Massachusetts)
ABSTRACT The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders.
FILED Tuesday, April 09, 2013
APPL NO 13/859054
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 39/00 (20130101)
A61K 2039/57 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
C07K 16/00 (20130101)
C07K 16/18 (20130101)
C07K 16/28 (20130101)
C07K 2317/34 (20130101)
C07K 2317/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657066 Pastan et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Ira H. Pastan (Potomac, Maryland);  Masanori Onda (Rockville, Maryland);  Wenhai Liu (Plantsville, Connecticut)
ABSTRACT The invention provides a Pseudomonas exotoxin A (PE) comprising an amino acid sequence having a substitution of one or more of amino acid residues E420, D463, Y481, L516, R563, D581, D589, and K606, wherein the amino acid residues are defined by reference to SEQ ID NO: 1. The invention further provides related chimeric molecules, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions. Methods of treating or preventing cancer in a mammal, methods of inhibiting the growth of a target cell, methods of producing the PE, and methods of producing the chimeric molecule are further provided by the invention.
FILED Friday, October 30, 2015
APPL NO 14/927645
ART UNIT 1676 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/164 (20130101)
A61K 47/48484 (20130101)

Peptides
C07K 14/21 (20130101) Original (OR) Class
C07K 16/30 (20130101)
C07K 16/1214 (20130101)
C07K 16/2851 (20130101)
C07K 16/2896 (20130101)
C07K 2317/34 (20130101)
C07K 2317/56 (20130101)
C07K 2317/622 (20130101)
C07K 2319/01 (20130101)
C07K 2319/55 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657073 Distelhorst et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Clark Distelhorst (Shaker Heights, Ohio);  Yiping Rong (Baoshan, China PRC)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Clark Distelhorst (Shaker Heights, Ohio);  Yiping Rong (Baoshan, China PRC)
ABSTRACT A protease resistant polypeptide includes an amino acid sequence that has a sequence identity at least 80% homologous to about 10 to 80 consecutive amino acids of SEQ ID NO:1.
FILED Thursday, September 01, 2011
APPL NO 13/819980
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/17 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/705 (20130101)
C07K 14/4703 (20130101) Original (OR) Class
C07K 14/4747 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657075 Mohammadi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Moosa Mohammadi (Scarsdale, New York);  Regina Goetz (New York, New York)
ABSTRACT The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and the C-terminus includes a C-terminal portion of an FGF23 molecule. The portion of the paracrine FGF is modified to decrease binding affinity for heparin and/or heparan sulfate compared to the portion without the modification. The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, methods for treating a subject suffering from a disorder, and methods of screening for compounds with enhanced binding affinity for the αKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention.
FILED Friday, March 15, 2013
APPL NO 13/839051
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1825 (20130101)
A61K 38/1825 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 14/50 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657077 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Shulin Li (Houston, Texas);  Jeffry Cutrera (Houston, Texas);  Xueqing Xia (Houston, Texas)
ASSIGNEE(S) BOARD OF SUPERVISORS OF LOUISIANA STATE (, None);  UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana)
INVENTOR(S) Shulin Li (Houston, Texas);  Jeffry Cutrera (Houston, Texas);  Xueqing Xia (Houston, Texas)
ABSTRACT A mini-peptide and its analogs have been found to target gene products to tumors. The peptide, named Carcinoma Homing Peptide (CHP), increased the tumor accumulation of the reporter gene products in five independent tumor models, including one human xenogeneic model. A CHP-IL-12 fusion gene was also developed using CHP and the p40 subunit of IL-12. The product from CHP-IL-12 fusion gene therapy increased accumulation of IL-12 in the tumor environment. In three tumor models, CHP-IL-12 gene therapy inhibited distal tumor growth. In a spontaneous lung metastasis model, inhibition of metastatic tumor growth was improved compared to wild-type IL-12 gene therapy, and in a squamous cell carcinoma model, toxic liver lesions were reduced. The receptor for CHP was identified as vimentin. CHP can be used to improve the efficacy and safety of targeted cancer treatments.
FILED Thursday, February 09, 2012
APPL NO 13/370011
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 38/208 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/5434 (20130101) Original (OR) Class
C07K 2319/33 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57415 (20130101)
G01N 33/57419 (20130101)
G01N 33/57423 (20130101)
G01N 33/57492 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657078 Castillo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) PharmaIN Corporation (Bothell, Washington)
ASSIGNEE(S) PHARMAIN CORPORATION (Bothell, Washington)
INVENTOR(S) Gerardo M. Castillo (Bothell, Washington);  Elijah Bolotin (Bothell, Washington)
ABSTRACT The invention describes compositions of peptide analogs that are active in blood or cleavable in blood to release an active peptide. The peptide analogs have a general formula: A-(Cm)x-Peptide (SEQ ID NO: 76), wherein A is hydrophobic moiety or a metal binding moiety, e.g., a chemical group or moiety containing 1) an alkyl group having 6 to 36 carbon units, 2) a nitrilotriacetic acid group, 3) an imidiodacetic acid group, or 4) a moiety of formula (ZyHisw)p (SEQ ID NO: 50), wherein Z is any amino acid residue other than histidine, His is histidine, y is an integer from 0-6; w is an integer from 1-6; and p is an integer from 1-6; wherein if A has alkyl group with 6 to 36 carbon units x is greater than 0; and Cm is a cleavable moiety consisting of glycine or alanine or lysine or arginine or N-Arginine or N-lysine, wherein x is an integer between 0-6 and N may be any amino acid or none. The peptide analogs are complexed with polymeric carrier to provide enhanced half-life.
FILED Monday, June 15, 2015
APPL NO 14/739312
ART UNIT 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 47/48038 (20130101)

Peptides
C07K 7/16 (20130101)
C07K 14/485 (20130101)
C07K 14/575 (20130101)
C07K 14/57563 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657096 Dimitrov et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Dimiter S. Dimitrov (Frederick, Maryland);  Weizao Chen (Frederick, Maryland)
ABSTRACT Antibodies and antibody fragments that bind to insulin-like growth factor (IGF) 1 receptor (IGF-1R) or IGF-2, as well as methods of using the antibodies for inhibiting the IGF-mediated signaling pathway, inhibiting IGF-1R signaling, and treating cancer, are described. A method of detecting the presence of IGF-1R or IGF-2 in a sample using the disclosed antibodies and antibody fragments is also described.
FILED Wednesday, May 13, 2015
APPL NO 14/710875
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39591 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/22 (20130101) Original (OR) Class
C07K 16/2863 (20130101)
C07K 2317/21 (20130101)
C07K 2317/33 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/569 (20130101)
C07K 2319/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 2333/71 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657101 Ravetch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Jeffrey V. Ravetch (New York, New York);  Rene G. Ott (New York, New York)
ABSTRACT The present invention provides reagents, methods and systems for predicting the inhibitory activity of an antibody or variant thereof comprising: determining a binding affinity of the antibody or variant thereof to a Fc activating receptor; determining a binding affinity of the antibody or variant thereof to a Fc inhibitory receptor, and calculating the ratio of said activating binding affinity to said inhibitory binding affinity (A/I ratio), wherein the magnitude of said ratio is less than one (1).
FILED Tuesday, December 03, 2013
APPL NO 14/095542
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)

Peptides
C07K 16/2803 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/59 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657103 Torres et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) NEW YORK UNIVERSITY (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Victor J. Torres (New York, New York);  Ashley L. Dumont (New York, New York)
ABSTRACT The present invention relates to methods of treating and preventing Staphylococcus aureus infection and/or a condition resulting from a S. aureus infection a subject that involves administering a CD11b inhibitor. The present invention further relates to a non-human transgenic animal expressing human CD11b and its use in methods of identifying novel therapeutics for the treatment and prevention of Staphylococcus aureus infection and/or a condition resulting from a S. aureus infection.
FILED Friday, March 15, 2013
APPL NO 14/398293
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1741 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/31 (20130101)
C07K 14/473 (20130101)
C07K 14/4354 (20130101)
C07K 14/70553 (20130101)
C07K 16/2845 (20130101) Original (OR) Class
C07K 2317/76 (20130101)
C07K 2319/21 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56938 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657105 Forman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Stephen Forman (Duarte, California);  Armen Mardiros (Glendale, California);  Christine E. Brown (Duarte, California);  Uma Maheswara Rao Jonnalagadda (Troy, Michigan)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Stephen Forman (Duarte, California);  Armen Mardiros (Glendale, California);  Christine E. Brown (Duarte, California);  Uma Maheswara Rao Jonnalagadda (Troy, Michigan)
ABSTRACT A family of chimeric antigen receptors (CARs) containing a CD123 specific scFv was developed to target different epitopes on CD123. In some embodiments, such a CD123 chimeric antigen receptor (CD123CAR) gene includes an anti-CD123 scFv region fused in frame to a modified IgG4 hinge region comprising an S228P substitution, an L235E substitution, and optionally an N297Q substitution; a costimulatory signaling domain; and a T cell receptor (TCR) zeta chain signaling domain. When expressed in healthy donor T cells (CD4/CD8), the CD123CARs redirect T cell specificity and mediated potent effector activity against CD123+ cell lines as well as primary AML patient samples. Further, T cells obtained from patients with active AML can be modified to express CD123CAR genes and are able to lyse autologous AML blasts in vitro. Finally, a single dose of 5.0×106 CAR123 T cells results in significantly delayed leukemic progression in mice. These results suggest that CD123CAR-transduced T cells may be used as an immunotherapy for the treatment of high risk AML.
FILED Friday, March 15, 2013
APPL NO 13/844048
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/7051 (20130101)
C07K 16/2866 (20130101) Original (OR) Class
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657269 Arya et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Bira Arya (Ellicott City, Maryland);  Purevdorj B. Olkhanud (Parkville, Maryland);  Monica Bodogai (Baltimore, Maryland)
ABSTRACT Regulatory B cells (tBreg) are disclosed herein. These regulatory B cells express CD25 (CD25+) a pan B cell marker such as B220 (B220+), and also express CD19 (CD19+). These regulatory B cells suppress resting and activated T cells in cell contact-dependent manner. Methods for generating these regulatory B cells are also disclosed herein, as are methods for using these regulatory B cells to produce regulatory T cells (Treg). In some embodiments, methods for treating an immune-mediated disorder, such as an autoimmune disease, transplant rejection, graft-versus-host disease or inflammation, are disclosed. These methods include increasing regulatory B cell number or activity and/or by administering autologous regulatory B cells. Methods for treating cancer are also disclosed herein. These methods include decreasing regulatory B cell activity and/or number.
FILED Wednesday, November 25, 2015
APPL NO 14/952768
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2035/122 (20130101)
A61K 2035/124 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0635 (20130101)
C12N 5/0637 (20130101) Original (OR) Class
C12N 2502/30 (20130101)
C12N 2502/1107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657272 Schlegel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Georgetown University (Washington, District of Columbia)
ASSIGNEE(S) Georgetown University (Washington, District of Columbia)
INVENTOR(S) Richard Schlegel (Rockville, Maryland);  Xuefeng Liu (Gaithersburg, Maryland)
ABSTRACT The present invention is directed towards methods of culturing non-keratinocyte epithelial cells, with the methods comprising culturing non-keratinocyte epithelial cells in the presence of feeder cells and a calcium-containing medium while inhibiting the activity of Rho kinase (ROCK) in the feeder cell, the non-keratinocyte epithelial cells or both during culturing.
FILED Friday, September 26, 2014
APPL NO 14/498089
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/067 (20130101)
C12N 5/0625 (20130101)
C12N 5/0631 (20130101)
C12N 5/0683 (20130101) Original (OR) Class
C12N 5/0688 (20130101)
C12N 2500/05 (20130101)
C12N 2500/40 (20130101)
C12N 2501/01 (20130101)
C12N 2501/11 (20130101)
C12N 2501/33 (20130101)
C12N 2501/39 (20130101)
C12N 2501/727 (20130101)
C12N 2502/13 (20130101)
C12N 2502/1323 (20130101)
C12N 2503/02 (20130101)
C12N 2510/04 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657292 Rivera et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Juan Rivera (Mechanicsburg, Pennsylvania);  Nicolas Charles (Asnieres sur Seine, France)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Juan Rivera (Mechanicsburg, Pennsylvania);  Nicolas Charles (Asnieres sur Seine, France)
ABSTRACT The invention features compositions comprising agents that inhibit or reduce self-reactive IgE and/or basophils, and related methods of using the compositions for treating or preventing lupus, lupus nephritis, and lupus-related disorders.
FILED Wednesday, November 24, 2010
APPL NO 13/989744
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/675 (20130101)
A61K 31/5383 (20130101)
A61K 31/5383 (20130101)
A61K 39/395 (20130101)
A61K 39/39533 (20130101)
A61K 39/39566 (20130101)
A61K 39/39566 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 16/2803 (20130101)
C07K 16/4291 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657350 Elenitoba-Johnson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Kojo Elenitoba-Johnson (Ann Arbor, Michigan);  Thirunavukkarasu Velusamy (Ann Arbor, Michigan);  Nallasivam Palanisamy (Ann Arbor, Michigan);  Anagh Sahasrabuddhe (Ann Arbor, Michigan);  Megan Lim (Ann Arbor, Michigan);  Arul Chinnaiyan (Plymouth, Michigan)
ABSTRACT Provided herein are kits, compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent RNA fusions as diagnostic markers and clinical targets for leukemia.
FILED Tuesday, May 06, 2014
APPL NO 14/271175
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57426 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657361 Munoz-Jordan et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Dept of Health and Human Services (Washington, District of Columbia);  Jorge L. Munoz-Jordan (Puerto Rico, Puerto Rico);  Edgardo Vergne (Sabanera, Puerto Rico);  Gilberto Santiago (Guaynabo, Puerto Rico)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Jorge L. Munoz-Jordan (Puerto Rico, Puerto Rico);  Edgardo Vergne (Sabanera, Puerto Rico);  Gilberto Santiago (Guaynabo, Puerto Rico)
ABSTRACT Processes for detecting Dengue virus (DENV) nucleic acid in a sample are provided including producing an amplification product by amplifying DENV nucleotide sequence and detection of an amplification by hybridization of a probe or other technique. The processes use primers or probes with introduced mutations and or degenerate bases that provide excellent superiority in detection and serotyping of DENV in a sample.
FILED Thursday, October 25, 2012
APPL NO 14/354972
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/701 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658060 Molnar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Alyosha Molnar (Ithaca, New York);  Albert Wang (Ithaca, New York);  Patrick Gill (Sunnyvale, California)
ABSTRACT An angle-sensitive pixel (ASP) device that uses the Talbot effect to detect the local intensity and incident angle of light includes a phase grating disposed above a photodiode assembly or a phase grating disposed above an analyzer grating that is disposed above a photodiode assembly. When illuminated by a plane wave, the upper grating generates a self-image at a selected Talbot depth. Several such structures, tuned to different incident angles, are sufficient to extract local incident angle and intensity. Arrays of such structures are sufficient to localize light sources in three dimensions without any additional optics.
FILED Monday, August 18, 2014
APPL NO 14/462039
ART UNIT 2878 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/14 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 2201/062 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/782 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1446 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658139 Hering et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) TSI Incorporated (Shoreview, Minnesota)
ASSIGNEE(S) TSI INCORPORATED (Shoreview, Minnesota);  AEROSOL DYNAMICS INC. (Berkley, California)
INVENTOR(S) Susanne V. Hering (Berkeley, California);  Gregory S. Lewis (Berkeley, California);  Arantzazu Eiguren Fernandez (El Cerrito, California);  Frederick Quant (Shoreview, Minnesota);  Kenneth R. Farmer, II (Lake Elmo, Minnesota)
ABSTRACT A system and a method is described herein for the collection of small particles in a concentrated manner, whereby particles are deposited onto a solid surface or collected into a volume of liquid. The collected samples readily interface to any of a number of different elemental, chemical, or biological or other analysis techniques.
FILED Wednesday, August 28, 2013
APPL NO 14/012818
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2202 (20130101) Original (OR) Class
G01N 1/2208 (20130101)
G01N 1/2211 (20130101)
G01N 15/065 (20130101)
G01N 2001/2217 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658142 Richardson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) David Richardson (Chandler, Arizona);  Thai Tran (Phoenix, Arizona);  Dmitry Derkach (Gilbert, Arizona);  Colleen Ziegler (Tempe, Arizona)
ABSTRACT Methods and apparatuses are provided for extraction and collection of sets of one or more cells from a formalin-fixed paraffin embedded tissue sample. A laser is used to remove sets of one or more cells from an immobilized sample within a microfluidic device, and a fluid flow element washes the removed set of one or more cells away from the immobilized sample, preferably to be collected in a downstream sample collection device. Morphological and/or positional information may be preserved to permit at least one technique (e.g., amplification, sequencing, and/or analytical, optionally performed after cells are lysed downstream of the microfluidic device) to be related to the original spatial location of the set of one or more cells in the immobilized sample.
FILED Thursday, April 14, 2016
APPL NO 15/099121
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/286 (20130101) Original (OR) Class
G01N 2001/2886 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658222 Moll et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MBIO DIAGONISTICS, INC. (Boulder, Colorado)
ASSIGNEE(S) Mbio Diagnostics, Inc. (Boulder, Colorado)
INVENTOR(S) Kevin D. Moll (Boulder, Colorado);  Kurt R. Vogel (Boulder, Colorado);  Marie J. Delaney (Boulder, Colorado);  Michael J. Lochhead (Boulder, Colorado);  Christopher J. Myatt (Boulder, Colorado)
ABSTRACT A cartridge for processing a sample includes (a) a planar waveguide with upper and lower planar surfaces defining an optical axis therebetween, wherein the upper planar surface has a plurality of capture molecules bound thereto, (b) a lens portion, coupled to the planar waveguide, for focusing and refracting a light beam propagating parallel to, but offset from, the optical axis such that the light beam couples into the planar waveguide and propagates therein along the optical axis at a non-zero, internal propagation angle β relative to the upper planar surface, and (c) a sample chamber for positioning the sample in contact with the plurality of capture molecules such that a target analyte of the sample is detectable through (i) an assay involving the target analyte and the capture molecules and (ii) evanescent illumination of the assay using the light beam within the planar waveguide.
FILED Monday, December 14, 2015
APPL NO 14/968583
ART UNIT 2874 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5023 (20130101)
B01L 3/502715 (20130101)
B01L 9/52 (20130101)
B01L 2300/0636 (20130101)
B01L 2300/0654 (20130101)
B01L 2300/0825 (20130101)
B01L 2400/0406 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/648 (20130101)
G01N 21/6452 (20130101)
G01N 21/7703 (20130101)
G01N 33/54373 (20130101) Original (OR) Class
G01N 2021/6439 (20130101)
G01N 2201/0221 (20130101)
G01N 2201/0612 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/003 (20130101)
G02B 6/0095 (20130101)
G02B 6/4291 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658224 Siegel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Donald Siegel (Philadelphia, Pennsylvania);  Carlos F. Barbas, III (Solana Beach, California)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania);  The Scripps Research Insitute (La Jolla, California)
INVENTOR(S) Donald Siegel (Philadelphia, Pennsylvania);  Carlos F. Barbas, III (Solana Beach, California)
ABSTRACT The present invention relates to novel methods for detecting a member of a known binding pair in a sample, including a cell, where one member of the pair (termed the “receptor”) is expressed by a bacteriophage, which phage is then used to detect the presence of the other member of the pair (termed the “ligand” or “target”). Rather than detecting the binding of the phage using antibody-based technology, the present invention relates to detecting marker molecule associated with the phage. In one aspect, the invention relates to identifying an antigen-bearing moiety (e.g., a red blood cell antigen) of interest present on a cell, e.g., a red blood cell, using antibody-displaying bacteriophage, as well as detecting anti-red blood cell auto- or alloantibodies and/or complement in a sample, using antiglobulin reagent-displaying bacteriophage and detecting a marker molecule associated with the phage. In one aspect, the phenotype of the phage is not linked with the genotype of the phage.
FILED Tuesday, November 14, 2006
APPL NO 12/085618
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/555 (20130101) Original (OR) Class
G01N 33/6854 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658228 Miklos et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland University Junior University (Palo Alto, California)
INVENTOR(S) David B. Miklos (Stanford, California);  Bita Sahaf (Palo Alto, California);  Leonore A. Herzenberg (Stanford, California)
ABSTRACT The described invention comprises a method for detecting the onset or monitoring the recurrence of chronic graft versus host disease (cGVHD) in a transplantation patient. The method comprises isolating peripheral blood mononuclear cells (PBMCs) from the transplantation patient and analyzing the isolated PBMCs to detect a biomarker specific for a donor cell. The detection of the biomarker is indicative of the onset or recurrence of cGVHD in the transplantation patient.
FILED Tuesday, March 12, 2013
APPL NO 13/796344
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56972 (20130101) Original (OR) Class
G01N 2333/70503 (20130101)
G01N 2800/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658233 Baron et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Jeffrey Baron (North Potomac, Maryland);  Youn Hee Jee (Bethesda, Maryland)
ABSTRACT The invention provides methods and kits for diagnosing a growth in a subject by providing a sample of a growth taken from a subject, determining the level of midkine or pleiotrophin in the sample by an immunoassay, and comparing the level of midkine or pleiotrophin determined from the sample with a control. An increased level of midkine or pleiotrophin in the sample as compared to the control is diagnostic of a malignant growth, whereas an equivalent or decreased level of midkine or pleiotrophin in the sample as compared to the control is diagnostic of a benign growth.
FILED Friday, February 17, 2017
APPL NO 15/435880
ART UNIT 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/543 (20130101)
G01N 33/57488 (20130101) Original (OR) Class
G01N 2333/475 (20130101)
G01N 2800/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658470 Applegate et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Raymond A. Applegate (Houston, Texas);  Jason D. Marsack (Houston, Texas);  Konrad Pesudovs (Gleneig, Australia);  Yue Shi (Houston, Texas)
ASSIGNEE(S) University of Houston System (Houston, Texas)
INVENTOR(S) Raymond A. Applegate (Houston, Texas);  Jason D. Marsack (Houston, Texas);  Konrad Pesudovs (Gleneig, Australia);  Yue Shi (Houston, Texas)
ABSTRACT Provided herein is a computer program product comprising a non-transitory computer-readable medium storing an algorithm to optimize a wavefront guided correction for a custom ophthalmic lens. The correction is determined from inputs of quantified wavefront error and registration uncertainty and a metric predictive of a visual performance task of interest and provides a level of visual performance within a user-defined performance range. Also provided is a method for optimizing a wavefront guided correction for a custom ophthalmic lens via inputting residual wavefront error values and quantified translational and rotational movements into an algorithm configured to determine the optimal wavefront guided correction therefrom and a custom ophthalmic lens comprising the correction.
FILED Thursday, February 27, 2014
APPL NO 14/191902
ART UNIT 2872 — Optics
CURRENT CPC
Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses
G02C 7/04 (20130101) Original (OR) Class
G02C 7/027 (20130101)
G02C 2202/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659044 Sarrafzadeh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Library of Medicine (NLM)
APPLICANT(S) Majid Sarrafzadeh (Anaheim Hills, California);  Jonathan S. Woodbridge (Los Angeles, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Majid Sarrafzadeh (Anaheim Hills, California);  Jonathan S. Woodbridge (Los Angeles, California)
ABSTRACT A saliency function is computed to indicate the saliency of each of a plurality of data points in a dataset. For each local maximum in the saliency function, a segment of the dataset is inserted into an index.
FILED Thursday, July 19, 2012
APPL NO 14/233091
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/30244 (20130101)
G06F 17/30321 (20130101) Original (OR) Class
G06F 17/30477 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659145 Sayood et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Khalid Sayood (Lincoln, Nebraska);  Sam Way (Boulder, Colorado);  Ozkan Ufuk Nalbantoglu (Lincoln, Nebraska);  George Garrity (Okemos, Michigan)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska);  NamesforLife, LLC (Lansing, Michigan)
INVENTOR(S) Khalid Sayood (Lincoln, Nebraska);  Sam Way (Boulder, Colorado);  Ozkan Ufuk Nalbantoglu (Lincoln, Nebraska);  George Garrity (Okemos, Michigan)
ABSTRACT DNA sequences are analyzed using latent semantic analysis. A set of nucleotide sequences is received in which the set has a first number of sequences. A set of basis vectors is determined, in which the set has a second number of basis vectors, the second number being smaller than the first number. Each basis vector represents a specific combination of predetermined nucleotide segments. For each of the nucleotide sequences, an approximate representation of the nucleotide sequence is determined based on a combination of the basis vectors. For each pair of nucleotide sequences, a distance between the pair of nucleotide sequences is determined according the distance between the approximate representation of the pair of nucleotide sequences. The set of nucleotide sequences are classified based on the distances between the pairs of nucleotide sequences.
FILED Tuesday, July 30, 2013
APPL NO 13/954925
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electric Digital Data Processing
G06F 19/22 (20130101) Original (OR) Class
G06F 19/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659146 Bray et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Tyler Stuart Bray (Chicago, Illinois);  Juliesta Elaine Sylvester (Chicago, Illinois);  Stephen Joseph Kron (Oak Park, Illinois)
ASSIGNEE(S)
INVENTOR(S) Tyler Stuart Bray (Chicago, Illinois);  Juliesta Elaine Sylvester (Chicago, Illinois);  Stephen Joseph Kron (Oak Park, Illinois)
ABSTRACT This invention is a novel method for analysis of data that is produced by test equipment. The preferred embodiment is data produced by liquid chromatography tandem mass spectrometry (LC-MS/MS) equipment, using industry standard methods to generate the initial data from the test equipment. The invention is a method for processing of the data to promptly produce accurate, reliable, and meaningful data that can be used for critical decisions. The unique benefit of the method is to correct the multiple measurement and calculation errors that are inherent in the operation of laboratory equipment. Prior methods result in errors based on circumstances that are difficult to control, accuracy-related errors in machine measurements, and fundamental mathematical errors in the data processing software that is used with the laboratory equipment. As an added benefit, this novel method allows comprehensive simultaneous measurement and calculation of correlation of any and all peptide pairs in a single measurement, with the capability to support repeated measurements with changed conditions over time. This novel method allows robust, detailed, and comprehensive measurements of peptide activity and function, which results in substantial improvements over prior methods in accuracy, reliability, and efficiency.
FILED Monday, May 02, 2011
APPL NO 13/068026
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6848 (20130101)
G01N 2570/00 (20130101)

Electric Digital Data Processing
G06F 19/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659216 Nikitin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Alexei V. Nikitin (Lawrence, Kansas);  Mark G. Frei (Oviedo, Florida);  Naresh C. Bhavaraju (Lawrence, Kansas);  Ivan Osorio (Leawood, Kansas);  Ruslan L. Davidchack (Wigston, United Kingdom)
ASSIGNEE(S) Flint Hills Scientific, L.L.C. (Lawrence, Kansas)
INVENTOR(S) Alexei V. Nikitin (Lawrence, Kansas);  Mark G. Frei (Oviedo, Florida);  Naresh C. Bhavaraju (Lawrence, Kansas);  Ivan Osorio (Leawood, Kansas);  Ruslan L. Davidchack (Wigston, United Kingdom)
ABSTRACT A method, computer program, and system for real-time signal analysis providing characterization of temporally-evolving densities and distributions of signal features of arbitrary-type signals in a moving time window by tracking output of order statistic filters (also known as percentile, quantile, or rank-order filters). Given a raw input signal of arbitrary type, origin, or scale, the present invention enables automated quantification and detection of changes in the distribution of any set of quantifiable features of that signal as they occur in time. Furthermore, the present invention's ability to rapidly and accurately detect changes in certain features of an input signal can also enable prediction in cases where the detected changes associated with an increased likelihood of future signal changes.
FILED Monday, September 10, 2012
APPL NO 13/608551
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electric Digital Data Processing
G06F 17/10 (20130101)
G06F 17/18 (20130101)
G06F 19/24 (20130101)
G06F 19/345 (20130101)
G06F 19/3437 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00536 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659351 Aliaga et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Daniel Gerardo Aliaga (West Lafayette, Indiana);  Carlos Roberto Montalto Cruz (Seattle, Washington);  Ignacio Garcia Dorado (West Lafayette, Indiana)
ABSTRACT A method to generate an output image that improves observation of a target image viewed on a medium by an optical system is disclosed. The method includes receiving at least one target image by a processing system, receiving at least one parameter by the processing system, defining an error signal associated with the difference between calculated optical system observation of intermediate images and the at least one target image, minimizing the error signal, and generating an output image associated with the intermediate image having the minimized error.
FILED Thursday, March 12, 2015
APPL NO 14/656681
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/00 (20130101)
A61B 3/032 (20130101)

Image Data Processing or Generation, in General
G06T 5/001 (20130101) Original (OR) Class
G06T 5/003 (20130101)
G06T 2207/20056 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659368 Alsop et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Beth Israel Deaconess Medical Center (Boston, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) David Alsop (Newton, Massachusetts);  Li Zhao (Cambridge, Massachusetts)
ABSTRACT Systems and methods for generating a medical image of a subject that includes functional information. First, two medical images are acquired. One is weighted based on functional information reflecting physiological functions of the subject and the other weighted based on anatomic information of the subject. A difference image between the two images are generated. By subjecting the difference image and the second image to a localized kernel, a local similarity image is generated. Using the local similarity image, an improved difference image is generated. Lastly, by subtracting the improved difference image from the first image, an enhanced medical image that retains the functional information reflecting physiological functions of the subject is generated.
FILED Friday, May 15, 2015
APPL NO 14/714015
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/50 (20130101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10088 (20130101)
G06T 2207/10104 (20130101)
G06T 2207/10108 (20130101)
G06T 2207/20221 (20130101)
G06T 2207/30016 (20130101)
G06T 2207/30104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE46412 Desjardins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Adrien Desjardins (London, United Kingdom);  Benjamin J. Vakoc (Arlington, Massachusetts);  Guillermo J. Tearney (Cambridge, Massachusetts);  Brett Eugene Bouma (Quincy, Massachusetts)
ASSIGNEE(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
INVENTOR(S) Adrien Desjardins (London, United Kingdom);  Benjamin J. Vakoc (Arlington, Massachusetts);  Guillermo J. Tearney (Cambridge, Massachusetts);  Brett Eugene Bouma (Quincy, Massachusetts)
ABSTRACT Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro-magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third electro-magnetic radiations can be simultaneously detected, with the signals being associated with information for the sample at a plurality of depths thereof. The depths can be determined using at least one of the third electro-magnetic radiations without a need to utilize another one of the third electro-magnetic radiations.
FILED Wednesday, February 19, 2014
APPL NO 14/184537
ART UNIT 3992 — Central Reexamination Unit (Electrical)
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0073 (20130101)

Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02043 (20130101)
G01B 9/02087 (20130101)
G01B 9/02091 (20130101)
G01B 2290/70 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/4795 (20130101) Original (OR) Class
G01N 2021/4714 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 09655521 Iftimia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Physical Sciences, Inc. (Andover, Massachusetts)
ASSIGNEE(S) Physical Sciences, Inc. (Andover, Massachusetts);  Memorial Sloan-Kettering Cancer Center (New York, New York)
INVENTOR(S) Nicusor V. Iftimia (Chelmsford, Massachusetts);  Mircea Mujat (Acton, Massachusetts);  R. Daniel Ferguson (Melrose, Massachusetts);  Ankit H. Patel (Methuen, Massachusetts);  Milind Rajadhyaksha (New York, New York)
ABSTRACT A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path.
FILED Thursday, January 31, 2013
APPL NO 13/755741
ART UNIT 3737 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655815 Xiang et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Rong Xiang (San Diego, California);  He Zhou (San Diego, California);  Ralph A Reisfeld (La Jolla, California)
ABSTRACT A DNA vaccine suitable for eliciting an immune response against cancer cells comprises a DNA construct operably encoding a cancer-associated Inhibitor of Apoptosis-family protein and an immunoactive gene product, such as a cytokine or a ligand for a natural killer cell surface receptor, in a pharmaceutically acceptable carrier. A preferred cytokine is CCL21. Preferred ligands for a natural killer cell surface receptor include human MICA, human MICB, human ULBP1, human ULBP2, and human ULBP3. The cancer-associated Inhibitor of Apoptosis (IAP)-family protein is preferably a survivin protein or livin protein. Method of inhibiting tumor growth by administering the vaccine of the invention to a mammal is also described.
FILED Monday, May 05, 2014
APPL NO 14/269998
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle
A61J 1/05 (20130101) Original (OR) Class

Preparations for Medical, Dental, or Toilet Purposes
A61K 6/00 (20130101)
A61K 39/0011 (20130101)
A61K 2039/53 (20130101)
A61K 2039/523 (20130101)
A61K 2039/55516 (20130101)
A61K 2039/55522 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655953 Muro Galindo et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Icahn School of Medicine at Mount Sinai (New York, New York);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) Icahn School of Medicine at Mount Sinai (New York, New York);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Silvia Muro Galindo (Silver Spring, Maryland);  Vladimir R. Muzykantov (Bryn Athyn, Pennsylvania);  Edward Howard Schuchman (Haworth, New Jersey)
ABSTRACT The present invention relates to compositions and methods for delivering lysosomal proteins. The compositions and methods described herein permit the targeted delivery of exogenous lysosomal proteins to cell surface proteins that allow their internalization via non-clathrin pathways. The present invention further relates to the use of the compositions and methods for enzyme replacement therapy of lysosomal storage diseases. Nucleic acids, recombinant cells and kits useful for making and using the compositions of the invention are also provided.
FILED Thursday, October 16, 2014
APPL NO 14/516231
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/465 (20130101) Original (OR) Class
A61K 47/48561 (20130101)

Peptides
C07K 16/2821 (20130101)
C07K 2317/77 (20130101)
C07K 2319/035 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)

Enzymes
C12Y 301/04012 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2982 (20150115)
Y10T 428/2991 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655963 Suzuki et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE UAB RESEARCH FOUNDATION (Birmingham, Alabama);  US ARMY WALTER REED ARMY MEDICAL CENTER, CHIEF, OFFICE OF RESEARCH, MARKETING and POLICY DEV (Washington, District of Columbia);  JUNTENDO UNIVERSITY SCHOOL OF MEDICINE, DIVISION OF NEPHROLOGY, DEPARTMENT OF INTERNAL MEDICINE (Tokyo, Japan);  UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama);  US Army Walter Reed Army Medical Center, Chief, Office Of Research, Marketing and Policy Dev Walter Reed Army Institute of Research (Washington, District of Columbia);  Juntendo University School of Medicine, Division of Nephrology, Department of Internal Medicine (Tokyo, Japan);  University of Tennessee Research Foundation (Memphis, Tennessee)
INVENTOR(S) Hitoshi Suzuki (Hoover, Alabama);  Run Fan (Omaha, Nebraska);  Bruce A. Julian (Birmingham, Alabama);  Jan Novak (Pelham, Alabama);  Zina Moldoveanu (Birmingham, Alabama);  Zhixin Zhang (Omaha, Nebraska);  Milan Tomana (Birmingham, Alabama);  Jiri Mestecky (Birmingham, Alabama);  Robert J. Wyatt (Memphis, Tennessee);  Yasuhiko Tomino (Tokyo, Japan);  Yusuke Suzuki (Tokyo, Japan);  Stephen Olson (Rockville, Maryland);  Matthew B. Renfrow (Birmingham, Alabama)
ABSTRACT Provided are methods of diagnosing IgA nephropathy in a subject. Optionally, the methods comprise isolating an IgG from the subject and determining whether the IgG binds to a galactose-deficient IgA1. Optionally, the methods comprise providing a biological sample from the subject and detecting in the sample a mutation in a IGH gene, wherein the mutation is in a nucleotide sequence encoding a complementarity determining region 3 (CDR3) of a IGH variable region. Optionally, the methods comprise determining a level of IgG specific for a galactose-deficient IgA1 in the subject. Also provided are methods of treating or reducing the risk of developing IgA nephropathy in a subject.
FILED Friday, June 27, 2014
APPL NO 14/318082
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39541 (20130101) Original (OR) Class

Peptides
C07K 16/4283 (20130101)
C07K 2317/41 (20130101)
C07K 2317/55 (20130101)
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6854 (20130101)
G01N 33/6893 (20130101)
G01N 2800/347 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655967 Gurtner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
Armed Forces Institute of Regenerative Medicine (AFIRM)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Geoffrey C. Gurtner (Palo Alto, California);  Michael T. Longaker (Stanford, California);  Victor W. Wong (San Francisco, California)
ABSTRACT The formation of scars at a wound site is reduced by contacting the wound site with an effective dose of an inhibitor of focal adhesion kinase (FAK) activity or expression. Blockade of FAK is sufficient to prevent mechanical and inflammatory stimuli from activating MCP-1 pathways. In addition to these chemokine-mediated mechanisms, inhibition of FAK may control fibrosis by blocking fibroblast collagen production. Pharmacologic blockade of FAK significantly reduces scar formation in vivo.
FILED Wednesday, December 05, 2012
APPL NO 13/706186
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/506 (20130101)
A61K 31/506 (20130101)
A61K 45/06 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656050 Gregory et al.
FUNDED BY
Department of Defense (DOD)
United States Special Operations Command (SOCOM)
APPLICANT(S) Oregon Biomedical Engineering Institute (Wilsonville, Oregon)
ASSIGNEE(S) Oregon Biomedical Engineering Institute (Wilsonville, Oregon)
INVENTOR(S) Kenton W. Gregory (Portland, Oregon);  Lauryn L. Baranowski (Selah, Washington);  Arjun Kalyanpur (Edison, New Jersey);  Seanna Vine (Newburyport, Massachusetts);  Grant Blackwell (Bristol, United Kingdom);  Benjamin Margolis (San Bruno, California);  Steven Dell (Carlsbad, California)
ABSTRACT Embodiments herein comprise a hemostatic composition comprising a plurality of liquid expandable articles capable of expanding upon contact with a liquid. A suitable composition comprises a plurality of liquid-expandable articles that may be mechanically uncoupled from one another and therefore may be capable of moving independently from one another. The plurality of liquid-expandable articles may comprise a compressed material capable of a high-degree of expansion upon liquid contact.
FILED Tuesday, September 02, 2014
APPL NO 14/475281
ART UNIT 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/00008 (20130101)
A61F 13/00025 (20130101)
A61F 13/00034 (20130101)
A61F 13/36 (20130101)
A61F 13/44 (20130101)
A61F 13/00063 (20130101)
A61F 2013/00106 (20130101)
A61F 2013/00472 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/44 (20130101)
A61L 15/425 (20130101)
A61L 24/0015 (20130101)
A61L 2300/44 (20130101)
A61L 2300/418 (20130101)
A61L 2400/04 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 29/02 (20130101) Original (OR) Class
A61M 2205/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656290 Ehrenberg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
INVENTOR(S) Isaac M. Ehrenberg (Brookline, Massachusetts);  Bae-Ian Wu (Beavercreek, Ohio);  Sanjay Emani Sarma (Lexington, Massachusetts)
ABSTRACT A new 3D stencil mask guides deposition of a shaped structure, typically an electromagnetic device component, onto a non-planar surface. The 3D stencil mask includes islands and bridges from prior art two-dimensional lettering stencils, but raises the islands and stencils above the side of the 3D stencil mask facing a non-planar surface, forming undercuts, so that material particles, such as from vacuum metal deposition, will form connected shapes. The 3D stencil mask is also configures so that the dimensions of the resulting electromagnetic structures are altered from a simple projected image of a structure designed for a planar surface so that the electromagnetic properties of the deposited structure are more nearly the same as those of a corresponding structure on a planar surface.
FILED Monday, July 07, 2014
APPL NO 14/325351
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Apparatus for Applying Fluent Materials to Surfaces, in General
B05C 21/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656297 Liu
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Jiong Liu (East Brunswick, New Jersey)
ASSIGNEE(S) NEI Corporation (Somerset, New Jersey)
INVENTOR(S) Jiong Liu (East Brunswick, New Jersey)
ABSTRACT A pretreatment solution and process for pretreating steel substrates with an aqueous solution to form a thin partially crosslinked layer that passivates the steel surface and inhibits the formation of flash rust, in which the thin partially crosslinked layer is dried in ambient air, and the dried layer enhances the cathodic disbondment resistance of the overlying paint system. In the process an aqueous precursor solution (A) containing at least one amino-functional silane, at least one of a dissolved silicate or a dissolved aluminate and at least a metal salt; is mixed with an aqueous precursor solution (B) containing at least an epoxy resin. The molar amount of amino-functional silane in precursor solution (A) is at considerably lower than the stoichiometric amount that is needed for completing the crosslinking reaction with the epoxy resin in precursor solution (B) so that unreacted epoxy groups are made available for further crosslinking with the overlying paint.
FILED Monday, June 24, 2013
APPL NO 13/924836
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 5/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656704 Couture et al.
FUNDED BY
Department of Defense (DOD)
Assistant Secretary of Defense for Special Operations/Low-Intensity Conflict (ASD SOLIC)
Technical Support Working Group (TSWG)
APPLICANT(S) iRobot Corporation (Bedford, Massachusetts)
ASSIGNEE(S) IROBOT DEFENSE HOLDINGS, INC. (Chelmsford, Massachusetts)
INVENTOR(S) Adam P. Couture (Allston, Massachusetts);  Richard Page (Middleton, Massachusetts);  John P. O'Brien (Newton, Massachusetts);  Mikhail Filippov (Arlington, Massachusetts);  Andrew Shein (Winchester, Massachusetts)
ABSTRACT A robotic vehicle (10,100,150A,150B150C,160,1000,1000A,1000B,1000C) includes a chassis (20,106,152,162) having front and rear ends (20A,152A,20B,152B) and supported on right and left driven tracks (34,44,108,165). Right and left elongated flippers (50,60,102,154,164) are disposed on corresponding sides of the chassis and operable to pivot. A linkage (70,156,166) connects a payload deck assembly (D1,D2,D3,80,158,168,806), configured to support a removable functional payload, to the chassis. The linkage has a first end (70A) rotatably connected to the chassis at a first pivot (71), and a second end (70B) rotatably connected to the deck at a second pivot (73). Both of the first and second pivots include independently controllable pivot drivers (72,74) operable to rotatably position their corresponding pivots (71,73) to control both fore-aft position and pitch orientation of the payload deck (D1,D2,D3,80,158,168,806) with respect to the chassis (20,106,152,162).
FILED Friday, May 16, 2014
APPL NO 14/280123
ART UNIT 3611 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 5/005 (20130101)
B25J 11/0025 (20130101)

Motor Vehicles; Trailers
B62D 55/065 (20130101)
B62D 55/075 (20130101) Original (OR) Class
B62D 57/024 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656733 Legg
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jeffrey D. Legg (Chula Vista, California)
ABSTRACT A life preserver locator system for assisting in locating and rescuing persons located in body of water. The life preserver locator system includes a water permeable envelope attachable to a life preserving aid and having a deployable water-activated signal assembly. In one embodiment, the deployable water-activated signal assembly includes a water-activated gas inflator mechanism that on exposure to water, such as saltwater, automatically actuates to inflate a balloon. The balloon deploys from the envelope into the air on a cable attached to the life preserver locator system allowing establishment of a line of sight from a person in the water and a rescue vessel to the balloon. In one embodiment, a light emitting device, such as strobe light, on the balloon automatically activates to emit light, to assist the person in the water in locating the life preserving aid. When the person reaches the life preserving aid, the person can activate a switch on the water-activated signal assembly changing the appearance of the emitted light.
FILED Monday, April 25, 2016
APPL NO 15/137285
ART UNIT 3617 — Electrical Circuits and Systems
CURRENT CPC
Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects
B63C 9/18 (20130101)
B63C 9/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656859 Meyer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) David J. Meyer (Fairfax, Virginia);  Brian P. Downey (Alexandria, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David J. Meyer (Fairfax, Virginia);  Brian P. Downey (Alexandria, Virginia)
ABSTRACT A process for fabricating a suspended microelectromechanical system (MEMS) structure comprising epitaxial semiconductor functional layers that are partially or completely suspended over a substrate. A sacrificial release layer and a functional device layer are formed on a substrate. The functional device layer is etched to form windows in the functional device layer defining an outline of a suspended MEMS device to be formed from the functional device layer. The sacrificial release layer is then etched with a selective release etchant to remove the sacrificial release layer underneath the functional layer in the area defined by the windows to form the suspended MEMS structure.
FILED Thursday, April 16, 2015
APPL NO 14/687943
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00539 (20130101) Original (OR) Class
B81C 2201/0107 (20130101)
B81C 2201/0132 (20130101)
B81C 2201/0143 (20130101)
B81C 2201/0159 (20130101)
B81C 2201/0177 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657024 Punnonen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) STATegics, Inc. (South San Francisco, California)
ASSIGNEE(S) STATegics, Inc. (South San Francisco, California)
INVENTOR(S) Juha Punnonen (Belmont, California);  Jeffrey R. Spencer (South San Francisco, California);  Timothy J. Church (San Mateo, California);  Connie S. Tettenborn (Belmont, California);  Karen Lariosa-Willingham (Mountain View, California);  Dmitri Leonoudakis (San Rafael, California);  James L. Miller (Los Altos, California)
ABSTRACT Disclosed herein are erythropoietin-mimetic compounds of Formula I, which modulate the survival, function, or differentiation of, for example, kidney cells, neurons, erythroid cells, or other erythropoietin-responsive cells. The present invention also relates to compounds and methods that preferentially modulate cells expressing the tissue-protective erythropoietin receptor. The compounds of the invention are useful in preventing and treating diseases, such as anemia, organ injury, and diseases of the central nervous system, and as an adjunct to cellular treatments, such as stem cell therapies.
FILED Wednesday, November 20, 2013
APPL NO 14/646651
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657145 Sotzing et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
ASSIGNEE(S) THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S) Gregory Allen Sotzing (Storrs, Connecticut);  Aaron Baldwin (Canterbury, Connecticut)
ABSTRACT Disclosed are transition metal or group II metal ester polymers where the metal is an alkaline earth, transition metal or aluminum; methods of manufacture, and uses thereof. The metal ester polymers exhibit both high dielectric constant and low conductivity suitable for use as dielectric insulating materials.
FILED Tuesday, November 24, 2015
APPL NO 14/950940
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 79/00 (20130101) Original (OR) Class
C08G 79/10 (20130101)
C08G 79/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657484 Lazzaro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Matthew Lazzaro (Churchville, Maryland);  William Toth (Ocean, New Jersey)
ABSTRACT Various embodiments are described that relate to a rapid deployment communications tile. As opposed to running various data and/or power wires, a construction crew can use set of tiles that have built in data and/or power transmission capabilities. These tiles can be keyed such that they interlock together to form a relatively uniform surface, such that the surface can also be used as a floor. Further, the tiles can have hardware components that enable the data and/or power transmission capabilities. These hardware components can be environmentally protected such that their performance is not subject to environmental factors.
FILED Thursday, February 12, 2015
APPL NO 14/620707
ART UNIT 3633 — Static Structures, Supports and Furniture
CURRENT CPC
Finishing Work on Buildings, e.g Stairs, Floors
E04F 15/105 (20130101) Original (OR) Class
E04F 2201/095 (20130101)
E04F 2201/098 (20130101)
E04F 2290/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657642 Kanjiyani et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) HONEYWELL INTERNATIONAL INC. (Morristown, New Jersey)
ASSIGNEE(S) HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
INVENTOR(S) Shezan Kanjiyani (Glendale, Arizona);  John Gintert (Tempe, Arizona);  Rajiv Rana (Tempe, Arizona);  Lorenzo Crosatti (Phoenix, Arizona);  Bradley Reed Tucker (Chandler, Arizona);  Ed Zurmehly (Phoenix, Arizona)
ABSTRACT A turbine section includes a stator assembly having an inner diameter end wall, an outer diameter end wall, and a stator vane; a turbine rotor assembly including a rotor blade extending into the mainstream gas flow path; a housing including an annular shroud that circumscribes the rotor blade and at least partially defines the mainstream hot gas flow path; a first baffle arranged to define a first cavity with the outer diameter end wall of the stator assembly; a second baffle; and a third baffle arranged to define a second cavity with the second baffle and a third cavity with the shroud. The first cavity is fluidly coupled to the second cavity and the second cavity is fluidly coupled to the third cavity such that cooling air flows from the first cavity to the second cavity and from the second cavity to the third cavity.
FILED Thursday, March 27, 2014
APPL NO 14/227924
ART UNIT 3748 — Static Structures, Supports and Furniture
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/187 (20130101)
F01D 11/08 (20130101)
F01D 25/12 (20130101)
F01D 25/14 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/10 (20130101)
F02C 7/18 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/81 (20130101)
F05D 2260/201 (20130101)
F05D 2260/205 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/673 (20130101)
Y02T 50/676 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657756 Bostiga et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina)
INVENTOR(S) Richard H. Bostiga (Ellington, Connecticut);  Charles E. Reuter (Granby, Connecticut)
ABSTRACT An actuator system having various features is disclosed. An actuator system may have a first and a second electrohydraulic servo valve. A control selector may connect one of the electrohydraulic servo valves to a cylinder and may isolate the other electrohydraulic servo valve to ameliorate leakage in response to a switching solenoid valve operating. In this manner, one electrohydraulic servo valve may be connected to a cylinder to operate the cylinder, and the other electrohydraulic servo valve may be isolated from the cylinder, for example, to provide a standby electrohydraulic servo valve.
FILED Thursday, August 14, 2014
APPL NO 14/460055
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for
F15B 18/00 (20130101) Original (OR) Class
F15B 20/005 (20130101)
F15B 2211/30565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657884 Carte et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) David B. Carte (Colorado Springs, Colorado);  Marko Podplatnik (Ljubjana, Slovenia);  Nathan Tangeman (Colorado Springs, Colorado);  Nathan Davies (Colorado Springs, Colorado);  Ryan Boedeker (Colorado Springs, Colorado);  Kyle Fitle (Colorado Springs, Colorado);  Christopher Caldrone (Colorado Springs, Colorado);  Kelsey Brush (Colorado Springs, Colorado)
ABSTRACT A pipe crawler for crawling inside a pipe having an inside wall includes a front leg assembly that has front legs and feet. It also includes a rear leg assembly that has rear legs and feet. The rear leg assembly is disposed at a distance from the front leg assembly. A midsection operably couples the front leg assembly to the rear leg assembly and is configured to extend and contract the distance between the front leg assembly and the rear leg assembly. A plurality of lever arms are pivotably coupled between the front legs and their corresponding assemblies. The lever arms, in response to a force applied in an orientation traveling from the front of the pipe crawler to the rear of the pipe crawler, are configured to redirect a portion of the force into a normal force between the feet and the pipe inside wall.
FILED Monday, April 27, 2015
APPL NO 14/697589
ART UNIT 3617 — Fluid Handling and Dispensing
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 55/34 (20130101)
F16L 55/44 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658040 Vasudevan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armament Research, Development and Engineering Center (ARDEC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Srikanth Vasudevan (Shelton, Connecticut);  Paul Suchy (Parma, Ohio);  Matthew C. Birch (Madison, Alabama)
ASSIGNEE(S) Orbital Research Inc. (Cleveland, Ohio)
INVENTOR(S) Srikanth Vasudevan (Shelton, Connecticut);  Paul Suchy (Parma, Ohio);  Matthew C. Birch (Madison, Alabama)
ABSTRACT Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics.
FILED Tuesday, June 21, 2016
APPL NO 15/188093
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Weapon Sights; Aiming
F41G 7/222 (20130101)
F41G 7/2293 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/14 (20130101)
F42B 10/42 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658087 Baur et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as Represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Jeffrey W. Baur (Liberty Township, Ohio);  Matthew R. Maschmann (Columbia, Missouri);  Gregory J. Ehlert (Miamisburg, Ohio);  Benjamin T. Dickinson (Destin, Florida);  David M. Phillips (Dayton, Ohio)
ABSTRACT A method for making an artificial hair sensor, comprising the steps of: (a) depositing an electrode at each end of a microcapillary having an inside surface; (b) coating a structural fiber with alumina; (c) placing the alumina coated structural fiber inside the microcapillary, wherein part of the alumina coated structural fiber is in a spaced annular relationship with the microcapillary inside surface and part of the fiber extends outside the microcapillary; (d) placing the microcapillary and alumina coated structural fiber inside a heated furnace chamber; and, (e) injecting a vaporized catalyst into the heated furnace chamber. The vaporized catalyst may be a solution of ferrocene in xylene. The microcapillary may be made of glass.
FILED Wednesday, May 06, 2015
APPL NO 14/705944
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/56 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658105 Bayya et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Shyam S. Bayya (Ashburn, Virginia);  Daniel J. Gibson (Cheverly, Maryland);  Vinh Q. Nguyen (Fairfax, Virginia);  Jasbinder S. Sanghera (Ashburn, Virginia);  Jay Vizgaitis (Alexandria, Virginia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
INVENTOR(S) Shyam S. Bayya (Ashburn, Virginia);  Daniel J. Gibson (Cheverly, Maryland);  Vinh Q. Nguyen (Fairfax, Virginia);  Jasbinder S. Sanghera (Ashburn, Virginia);  Jay Vizgaitis (Alexandria, Virginia)
ABSTRACT A compact multispectral imaging system comprising a set of optical elements capable of simultaneously focusing light from one or more spectral bands (SWIR, MWIR, and LWIR) to a common focal plane and a detector capable of capturing the multispectral image, wherein the optical elements comprise optics made from new optical materials or in combination with existing optical materials that transmit in multispectral wavelength regions.
FILED Wednesday, September 09, 2015
APPL NO 14/848555
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/0208 (20130101)
G01J 3/2823 (20130101) Original (OR) Class
G01J 2003/2826 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658139 Hering et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) TSI Incorporated (Shoreview, Minnesota)
ASSIGNEE(S) TSI INCORPORATED (Shoreview, Minnesota);  AEROSOL DYNAMICS INC. (Berkley, California)
INVENTOR(S) Susanne V. Hering (Berkeley, California);  Gregory S. Lewis (Berkeley, California);  Arantzazu Eiguren Fernandez (El Cerrito, California);  Frederick Quant (Shoreview, Minnesota);  Kenneth R. Farmer, II (Lake Elmo, Minnesota)
ABSTRACT A system and a method is described herein for the collection of small particles in a concentrated manner, whereby particles are deposited onto a solid surface or collected into a volume of liquid. The collected samples readily interface to any of a number of different elemental, chemical, or biological or other analysis techniques.
FILED Wednesday, August 28, 2013
APPL NO 14/012818
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2202 (20130101) Original (OR) Class
G01N 1/2208 (20130101)
G01N 1/2211 (20130101)
G01N 15/065 (20130101)
G01N 2001/2217 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658314 Parks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Brandon Scott Parks (South Park, Pennsylvania);  Walter J. Keller, III (Bridgeville, Pennsylvania);  Jennting Timothy Hsu (Bethel Park, Pennsylvania)
ASSIGNEE(S) Nokomis, Inc. (Charleroi, Pennsylvania)
INVENTOR(S) Brandon Scott Parks (South Park, Pennsylvania);  Walter J. Keller, III (Bridgeville, Pennsylvania);  Jennting Timothy Hsu (Bethel Park, Pennsylvania)
ABSTRACT A system for identifying a real-world geographic location of an emission source emitting electromagnetic energy includes a platform configured for movement and an apparatus disposed on the platform and configured to collect and process, in a passive manner and during movement of the platform, at least a pair of successive samples of the electromagnetic energy emission and define angular and spatial coordinates of the emission source. The apparatus includes at least a pair of antennas, a receiver coupled to antennas and a processor executing a predetermined logic.
FILED Friday, March 02, 2012
APPL NO 13/410586
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/04 (20130101) Original (OR) Class
G01S 5/0221 (20130101)
G01S 5/0278 (20130101)
G01S 5/0284 (20130101)
G01S 5/0294 (20130101)
G01S 19/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658318 Forero et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATED OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
INVENTOR(S) Pedro A. Forero (San Diego, California);  Paul A. Baxley (San Diego, California)
ABSTRACT A system and a method involve acoustic source localization for multiple acoustic sources using passive sonar. Tracks are constructed based on source location maps (SLMs) that reveal the locations of the sources over a grid of tentative source locations. The proposed estimator for the SLMs performs coherent processing of broadband acoustic measurements, capitalizes on the sparse structure of the SLMs, and uses the prior SLM estimate to capture temporal information about the locations of the sources.
FILED Wednesday, January 27, 2016
APPL NO 15/008322
ART UNIT 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/808 (20130101)
G01S 5/18 (20130101)
G01S 5/22 (20130101) Original (OR) Class
G01S 15/04 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/001 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 1/44 (20130101)
H04R 1/406 (20130101)
H04R 3/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658398 Budd et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Russell A. Budd (North Salem, New York);  Daniel M. Kuchta (Patterson, New York);  Benjamin Giles Lee (New York, New York);  Laurent Schares (Sleepy Hollow, New York);  Clint Lee Schow (Ossining, New York)
ABSTRACT A system comprises a first optical component comprising at least one waveguide and at least one self-alignment feature; and a second optical component comprising at least another waveguide and at least another self-alignment feature; wherein the self-alignment feature of the second optical component engage to assist in optically-coupling the waveguide of the first optical component and the waveguide of the second optical component when the first optical component has a manufacturing tolerance in a given geometric dimension and is mounted in the second optical component.
FILED Tuesday, April 12, 2016
APPL NO 15/096996
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/125 (20130101) Original (OR) Class
G02B 6/423 (20130101)
G02B 6/3652 (20130101)
G02B 2006/12119 (20130101)
G02B 2006/12166 (20130101)
G02B 2006/12173 (20130101)
G02B 2006/12176 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 156/10 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658404 Ohnstein et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Honeywell International Inc. (Morristown, New Jersey)
ASSIGNEE(S) Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S) Thomas Ohnstein (Roseville, Minnesota);  Daniel Youngner (Maple Grove, Minnesota);  Mary Salit (Plymouth, Minnesota);  Jeff A. Ridley (Shorewood, Minnesota)
ABSTRACT Methods, apparatuses, and systems for design, fabrication, and use of an optical bench, as well as alignment and attachment of optical fibers are described herein. One apparatus includes an apparatus body, a first channel within the apparatus body for positioning of a first optical fiber directed along a first axis and a second channel within the apparatus body for positioning of a second optical fiber directed along a second axis, wherein the first axis is orthogonal to the second axis. The apparatus also includes a third optical fiber directed along the second axis and an optical element positioned along the first channel and second channel to focus a first light beam from the first optical fiber along the first axis and focus a second light beam from the second optical fiber along the second axis.
FILED Tuesday, April 14, 2015
APPL NO 14/686501
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/32 (20130101)
G02B 6/3616 (20130101)
G02B 6/3636 (20130101)
G02B 6/3652 (20130101) Original (OR) Class
G02B 6/3664 (20130101)
G02B 6/3692 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658510 Kippelen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Bernard Kippelen (Atlanta, Georgia);  Canek Fuentes-Hernandez (Atlanta, Georgia);  James June Fan Hsu (Atlanta, Georgia)
ABSTRACT An optical device capable of an ultrafast and large change of its reflection or absorption coefficient upon being excited by an ultrafast optical pulse with wavelength in the visible, near-infrared, or infrared spectral regions. The optical device includes, in sequential order, a first thick metallic layer, a first dielectric layer, a second thin metallic layer, and a second dielectric layer. The optical device acts as a nonlinear mirror that presents a large reflectance at low irradiance and a low reflectance at large irradiance. The optical device can further act as a nonlinear mirror that presents a linear and nonlinear reflectance with a large angular bandwidth.
FILED Friday, December 20, 2013
APPL NO 14/764100
ART UNIT 2872 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/17 (20130101)
G02F 1/19 (20130101)
G02F 1/21 (20130101) Original (OR) Class
G02F 1/0126 (20130101)
G02F 1/355 (20130101)
G02F 1/3523 (20130101)
G02F 2001/211 (20130101)
G02F 2203/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658512 Tabirian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia);  Beam Engineering for Advanced Measurements Co. (Orlando, Florida)
ASSIGNEE(S) Beam Engineering for Advanced Materials Co. (Orlando, Florida);  The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Nelson V. Tabirian (Winter Park, Florida);  Sarik R. Nersisyan (Winter Park, Florida);  Brian R. Kimball (Shrewsbury, Massachusetts);  Diane M. Steeves (Franklin, Massachusetts)
ABSTRACT A cycloidal diffractive waveplate (50) comprising first and second substrate layers (52, 54), a liquid crystal layer (60C, 60H) provided between the first and second substrate layers, and transparent positive electrodes (56) and transparent negative electrodes (58) provided on the first substrate layer. The liquid crystal layer has a diffractive state (60C) in which the optical axes of the liquid crystal molecules are periodically rotated across a plane of the waveplate and a non-diffractive state (60H) in which the optical axes of the liquid crystal molecules are all orientated in the same direction in the plane of the waveplate. The electrodes (56, 58) are arranged in an alternating series, such that when an electric voltage is applied to the electrodes an electric field is produced in the plane of the waveplate and the liquid crystal layer is switched from the diffractive state to the non-diffractive state. A method of manufacturing the cycloidal diffractive waveplate is also provided.
FILED Tuesday, January 28, 2014
APPL NO 14/165615
ART UNIT 2871 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/292 (20130101) Original (OR) Class
G02F 1/134363 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49155 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658940 Chen et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Tong Chen (Yorktown Heights, New York);  John Kevin O'Brien (South Salem, New York);  Zehra Noman Sura (Yorktown Heights, New York)
ABSTRACT Software-managed resources are used to utilize effective-to-real memory address translation for synchronization among processes executing on processor cores in a multi-core computing system. A failure to find a pre-determined effective memory address translation in an effective-to-real memory address translation table on a first processor core triggers an address translation exception in a second processor core and causes an exception handler on the second processor core to start a new process, thereby acting as a means to achieve synchronization among processes on the first processor core and the second processor core. The specific functionality is implemented in the exception handler, which is tailored to respond to the exception based on the address that generated it.
FILED Thursday, March 19, 2015
APPL NO 14/662789
ART UNIT 2136 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 8/65 (20130101)
G06F 8/751 (20130101)
G06F 9/4552 (20130101)
G06F 11/28 (20130101)
G06F 11/073 (20130101)
G06F 11/0772 (20130101)
G06F 11/0793 (20130101)
G06F 11/3632 (20130101) Original (OR) Class
G06F 12/1027 (20130101)
G06F 2212/684 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658987 Avron et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Haim Avron (White Plains, New York);  Kenneth L. Clarkson (Madison, New Jersey);  Huy Le Nguyen (Princeton, New Jersey);  David P. Woodruff (Mountain View, California)
ABSTRACT Embodiments of the invention relate to sketching for M-estimators for performing regression. One embodiment includes providing one or more sets of input data. A matrix A and a vector b are generated using the input data. A processor device is used for processing the matrix A and the vector b based on a randomized sketching matrix S. A vector x that minimizes a normalized measure function is determined based on the matrix A and the vector b. A relationship between the input data is determined based on the vector x.
FILED Thursday, May 15, 2014
APPL NO 14/279177
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Electric Digital Data Processing
G06F 17/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659189 Lee et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Wenke Lee (Atlanta, Georgia);  Alexandra Boldyreva (Atlanta, Georgia);  Chung Pak Ho (Atlanta, Georgia);  Billy Lau (Atlanta, Georgia);  Chengyu Song (Atlanta, Georgia)
ABSTRACT The disclosed technology includes techniques for improving data privacy in mobile communications over public cloud services. According to certain implementations, a novel conceptual layer may be interposed between the “application” layer and the “user” layer. In some implementations, the conceptual layer may be at least partially embodied by a transparent window or pane overlaid on top of existing app graphical user interfaces to: (1) intercept plaintext user input before transforming the input and feeding it to an underlying app; and (2) reverse transform output data from the app before displaying the plaintext data to the user. Accordingly, the conceptual layer may serve as a protective layer while preserving the original application workflow and look-and-feel.
FILED Tuesday, October 14, 2014
APPL NO 14/513680
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/6263 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0435 (20130101)

Wireless Communication Networks
H04W 12/00 (20130101)
H04W 12/02 (20130101)
H04W 88/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659257 Hodgin
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) AlphaTRAC, Inc. (Westminster, Colorado)
ASSIGNEE(S) AlphaTRAC, Inc. (Westminster, Colorado)
INVENTOR(S) Charles Reed Hodgin (Westminster, Colorado)
ABSTRACT A method and system that provide for decision support and/or training support in crisis decision-making situations are provided. In one implementation, a method identifies patterns from known cases based on information from a crisis event. Each of the known cases includes attributes and at least one outcome. The method also identifies a first subset of the known cases that relate to the identified patterns from the known cases. The method also analyzes the identified patterns to determine a cue that, if answered, will provide a second subset of the known cases including a more converged range of decision outcomes than the first subset.
FILED Monday, February 25, 2013
APPL NO 13/776486
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/0454 (20130101)
G06N 99/005 (20130101) Original (OR) Class

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 31/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659737 Eden et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) J. Gary Eden (Champaign, Illinois);  Sung-Jin Park (Champaign, Illinois);  JeKwon Yoon (Paju-Si, South Korea);  Kwang-Soo Kim (Champaign, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) J. Gary Eden (Champaign, Illinois);  Sung-Jin Park (Champaign, Illinois);  JeKwon Yoon (Paju-Si, South Korea);  Kwang-Soo Kim (Champaign, Illinois)
ABSTRACT Microstructured, irregular surfaces pose special challenges but coatings of the invention can uniformly coat irregular and microstructured surfaces with one or more thin layers of phosphor. Preferred embodiment coatings are used in microcavity plasma devices and the substrate is, for example, a device electrode with a patterned and microstructured dielectric surface. A method for forming a thin encapsulated phosphor coating of the invention applies a uniform paste of metal or polymer layer to the substrate. In another embodiment, a low temperature melting point metal is deposited on the substrate. Polymer particles are deposited on a metal layer, or a mixture of a phosphor particles and a solvent are deposited onto the uniform glass, metal or polymer layer. Sequential soft and hard baking with temperatures controlled to drive off the solvent will then soften or melt the lowest melting point constituents of the glass, metal or polymer layer, partially or fully embed the phosphor particles into glass, polymer, or metal layers, which partially or fully encapsulate the phosphor particles and/or serve to anchor the particles to a surface.
FILED Thursday, July 14, 2011
APPL NO 13/183255
ART UNIT 2879 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 9/222 (20130101)
H01J 29/20 (20130101) Original (OR) Class
H01J 61/44 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24421 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659824 Cheng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Joy Cheng (San Jose, California);  Matthew E. Colburn (Schenectady, New York);  Michael A. Guillorn (Yorktown Heights, New York);  Chi-Chun Liu (Altamont, New York);  Melia Tjio (San Jose, California);  HsinYu Tsai (White Plains, New York)
ABSTRACT Guiding pattern portions are formed on a surface of a lithographic material stack that is disposed on a surface of a semiconductor substrate. A copolymer layer is then formed between each neighboring pair of guiding pattern portions and thereafter a directed self-assembly process is performed that causes phase separation of the various polymeric domains of the copolymer layer. Each guiding pattern portion is selectively removed, followed by the removal of each first phase separated polymeric domain. Each second phase separated polymeric domain remains and is used as an etch mask in forming semiconductor fins in an upper semiconductor material portion of the semiconductor substrate.
FILED Tuesday, April 28, 2015
APPL NO 14/697693
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0273 (20130101)
H01L 21/845 (20130101)
H01L 21/3081 (20130101)
H01L 21/3086 (20130101)
H01L 21/823431 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660286 McNeilly
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Frank J. McNeilly (Portsmouth, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Frank J. McNeilly (Portsmouth, Rhode Island)
ABSTRACT An anode/cathode system is disclosed for use in a Benthic microbial fuel cell. Carbon cloth forms at least a portion of the anode and is disposed on one side of a water oxygen impermeable layer, which can be weighted around a periphery thereof to hold the anode against a water-sediment interface. Carbon cloth flaps or strands can be attached to the other side of the impermeable layer to form the cathode. The anode and cathode can be divided into sections with each section having an electrical lead coupled thereto. The system is deployed onto the seafloor with the anode side in contact with the water-sediment interface.
FILED Monday, March 24, 2014
APPL NO 14/222771
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/02 (20130101)
H01M 8/16 (20130101) Original (OR) Class
H01M 2250/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660322 Liu
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Yong Liu (San Marino, California)
ABSTRACT Apparatus, systems and methods provide for compensating for pointing errors that may occur when using a coarse positioning mechanism for pointing a payload toward a target. According to aspects of the disclosure, a coarse positioning mechanism is configured to compensate for pointing errors that may occur when pointing a payload toward a target over a large angular FOV. The coarse positioning mechanism may be configured for a variety of applications, such as precision tracking applications and precision pointing applications over a large angular FOV. The coarse positioning mechanism may include adjustment mechanisms for one or more axes that are used to adjust the pointing direction of the target.
FILED Tuesday, February 18, 2014
APPL NO 14/182860
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/125 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660582 Wang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Jian-Ping Wang (Shoreview, Minnesota);  Mahdi Jamali (Minneapolis, Minnesota)
ABSTRACT A device including a spin channel to transport a spin current, a nano-oscillator, and a magnetoresistive device that receives the spin current from the nano-oscillator. The nano-oscillator includes a magnetization state that oscillates between a first state and a second state in response to an input voltage or current. The oscillation of the nano-oscillator may induce the spin current within the spin channel. The magnetoresistive device includes a magnetization state that is set based at least in part on the received spin current.
FILED Friday, August 19, 2016
APPL NO 15/241169
ART UNIT 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 25/00 (20130101)

Information Storage Based on Relative Movement Between Record Carrier and Transducer
G11B 5/3909 (20130101)
G11B 5/3958 (20130101)
G11B 2005/3996 (20130101)

Static Stores
G11C 11/161 (20130101)
G11C 11/1673 (20130101)
G11C 11/1675 (20130101)
G11C 19/0808 (20130101)
G11C 19/0841 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 10/3254 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 43/08 (20130101)

Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 15/006 (20130101) Original (OR) Class

Pulse Technique
H03K 19/16 (20130101)
H03K 19/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660654 Matheny et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Matthew Matheny (Diamond Bar, California);  Michael L. Roukes (Pasadena, California);  Michael C. Cross (Arroyo Grande, California);  Luis Guillermo Villanueva Torrijo (Los Angeles, California);  Rassul Karabalin (Los Angeles, California)
ABSTRACT Synchronization of oscillators based on anharmonic nanoelectromechanical resonators. Experimental implimentation allows for unprecedented observation and control of parameters governing the dynamics of synchronization. Close quantitative agreement is found between experimental data and theory describing reactively coupled Duffing resonators with fully saturated feedback gain. In the synchonized state, a significant reduction in the phase noise of the oscillators is demonstrated, which is key for applications such as sensors and clocks. Oscillator networks constructed from nanomechanical resonators form an important laboratory to commercialize and study synchronization—given their high-quality factors, small footprint, and ease of co-integration with modern electronic signal processing technologies. Networks can be made including one-, two-, and three-dimensional networks. Triangular and square lattices can be made.
FILED Friday, October 25, 2013
APPL NO 14/063905
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/11 (20130101)

Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 5/30 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660757 Beranek et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Mark Beranek (Hollywood, Maryland);  Robert Boyd (St. Leonard, Maryland);  Nicholas Peterson (Lexington Park, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Mark Beranek (Hollywood, Maryland);  Robert Boyd (St. Leonard, Maryland);  Nicholas Peterson (Lexington Park, Maryland)
ABSTRACT The present invention is directed to a low latency fiber optic local area network with a network and a plurality of nodes connected through optical fibers. Each node has a plurality of bi-directional input/output interfaces. Each bi-directional input/output interface has a demultiplexer, at least one optical power coupler, a plurality of wavelength converters, and a plurality of internal optical waveguides. The internal optical waveguides extend from each wavelength converter and are for communication with the demultiplexer, the input fiber optic interface, and the optical fiber. Each optical power coupler has a fiber optic output interface for communication with other nodes, and each demultiplexer has a input fiber optic interface for communication with other nodes.
FILED Tuesday, June 09, 2015
APPL NO 14/734186
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 10/272 (20130101)
H04B 10/278 (20130101)

Multiplex Communication
H04J 14/028 (20130101)
H04J 14/0282 (20130101) Original (OR) Class
H04J 14/0284 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 09655573 Majewski et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Thomas Jefferson National Accelerator Facility (TJNAF)
Federally Funded Research and Development Center (FFRDC)
Operated by Jefferson Science Associates, LLC (JSA) at Newport News, VA
APPLICANT(S) West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S) WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia)
INVENTOR(S) Stanislaw Majewski (Charlottesville, Virginia);  Julie Brefczynski-Lewis (Morgantown, West Virginia)
ABSTRACT Various methods, systems and apparatus are provided for brain imaging during virtual reality stimulation. In one example, among others, a system for virtual ambulatory environment brain imaging includes a mobile brain imager configured to obtain positron emission tomography (PET) scans of a subject in motion, and a virtual reality (VR) system configured to provide one or more stimuli to the subject during the PET scans. In another example, a method for virtual ambulatory environment brain imaging includes providing stimulation to a subject through a virtual reality (VR) system; and obtaining a positron emission tomography (PET) scan of the subject while moving in response to the stimulation from the VR system. The mobile brain imager can be positioned on the subject with an array of imaging photodetector modules distributed about the head of the subject.
FILED Tuesday, December 15, 2015
APPL NO 14/969597
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/037 (20130101)
A61B 6/462 (20130101)
A61B 6/466 (20130101)
A61B 6/467 (20130101)
A61B 6/501 (20130101)
A61B 6/4405 (20130101) Original (OR) Class
A61B 6/5205 (20130101)
A61B 34/30 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656061 Cela et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) The University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Carlos Jose Cela (Salt Lake City, Utah);  Gianluca Lazzi (Salt Lake City, Utah)
ABSTRACT The present embodiments are directed to implantable electrode arrays having virtual electrodes. The virtual electrodes may improve the resolution of the implantable electrode array without the burden of corresponding complexity of electronic circuitry and wiring. In a particular embodiment, a virtual electrode may include one or more passive elements to help steer current to a specific location between the active electrodes. For example, a passive element may be a metalized layer on a substrate that is adjacent to, but not directly connected to an active electrode. In certain embodiments, an active electrode may be directly coupled to a power source via a conductive connection. Beneficially, the passive elements may help to increase the overall resolution of the implantable array by providing additional stimulation points without requiring additional wiring or driver circuitry for the passive elements.
FILED Friday, September 11, 2015
APPL NO 14/852147
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0531 (20130101)
A61N 1/0551 (20130101) Original (OR) Class
A61N 1/0553 (20130101)
A61N 1/36185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656205 Singh et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Surinder Prabhjot Singh (Schenectady, New York);  Harish Radhakrishna Acharya (Clifton Park, New York);  Robert James Perry (Niskayuna, New York);  John Brian McDermott (Rexford, New York)
ABSTRACT A system and method for treatment of a medium is disclosed. The system includes a plurality of separator zones and a plurality of heat transfer zones. Each of the separator zone and the heat transfer zone among the plurality of separator zones and heat transfer zones respectively, are disposed alternatively in a flow duct. Further, each separator zone includes an injector device for injecting a sorbent into the corresponding separator zone. Within the corresponding separator zone, the injected sorbent is reacted with a gaseous medium flowing in the flow duct, so as to generate a reacted gaseous medium and a reacted sorbent. Further, each heat transfer zone exchanges heat between the reacted gaseous medium fed from the corresponding separator zone and a heat transfer medium.
FILED Friday, June 28, 2013
APPL NO 13/931421
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/62 (20130101) Original (OR) Class
B01D 53/78 (20130101)
B01D 53/83 (20130101)
B01D 53/343 (20130101)
B01D 53/1406 (20130101)
B01D 53/1475 (20130101)
B01D 2252/2041 (20130101)
B01D 2252/20421 (20130101)
B01D 2252/20484 (20130101)
B01D 2252/20489 (20130101)
B01D 2257/504 (20130101)
B01D 2258/0283 (20130101)
B01D 2259/65 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/04 (20130101)
Y02C 10/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656243 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Donghai Wang (State College, Pennsylvania);  Fang Dai (State College, Pennsylvania);  Ran Yi (State College, Pennsylvania);  Jianto Zai (State College, Pennsylvania)
ABSTRACT We provide a mesoporous silicon material (PSi) prepared via a template-free and HF-free process. The production process is facile and scalable, and it may be conducted under mild reaction conditions. The silicon may be produced directly by the reduction of a silicon-halogenide precursor (for example, SiCl4) with an alkaline alloy (for example, NaK alloy). The resulting Si-salt matrix is then annealed for the pore formation and crystallite growth. Final product is obtained by removal of the salt by-products with water.
FILED Thursday, July 10, 2014
APPL NO 14/328136
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/06 (20130101) Original (OR) Class
B01J 35/004 (20130101)
B01J 35/1019 (20130101)
B01J 35/1023 (20130101)
B01J 35/1042 (20130101)
B01J 35/1047 (20130101)
B01J 35/1061 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/033 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/386 (20130101)
H01M 4/622 (20130101)
H01M 4/623 (20130101)
H01M 8/0606 (20130101)
H01M 10/0525 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/324 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/56 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656728 Mundon
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Oscilla Power, Inc. (Seattle, Washington)
ASSIGNEE(S) Oscilla Power, Inc. (Seattle, Washington)
INVENTOR(S) Timothy R Mundon (Seattle, Washington)
ABSTRACT A system for transporting a buoy and a heave plate. The system includes a buoy and a heave plate. An outer surface of the buoy has a first geometrical shape. A surface of the heave plate has a geometrical shape complementary to the first geometrical shape of the buoy. The complementary shapes of the buoy and the heave plate facilitate coupling of the heave plate to the outer surface of the buoy in a transport mode.
FILED Friday, July 24, 2015
APPL NO 14/808436
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 22/18 (20130101)
B63B 22/20 (20130101) Original (OR) Class

Hydraulic Engineering
E02B 9/08 (20130101)

Machines or Engines for Liquids
F03B 13/20 (20130101)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2230/60 (20130101)
F05B 2260/02 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/34 (20130101)

Dynamo-electric Machines
H02K 7/1876 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/18 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656881 Steinhour
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Leif Alexi Steinhour (Berkeley, California)
ASSIGNEE(S)
INVENTOR(S) Leif Alexi Steinhour (Berkeley, California)
ABSTRACT Systems, methods, and apparatus are provided for purifying and pumping liquids, and more particularly, for purifying and pumping water. The apparatus includes a chamber including a top portion and a bottom portion. A surface configured to be heated is proximate the bottom portion of the chamber. A baffle is disposed within the chamber and above the surface. The baffle is disposed at an angle relative to a vertical direction. The chamber further includes an inlet and a first outlet. The surface heats a liquid in the chamber, causing the liquid to boil. In operation, bubbles rise from the surface and are forced in a horizontal direction by the baffle disposed in the chamber.
FILED Thursday, March 13, 2014
APPL NO 14/210226
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Separation
B01D 1/04 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/14 (20130101) Original (OR) Class
C02F 1/325 (20130101)
C02F 2201/3228 (20130101)
C02F 2303/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656926 Thoma et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Steven G. Thoma (Albuquerque, New Mexico);  Mark C Grubelich (Albuquerque, New Mexico);  Mathias C. Celina (Albuquerque, New Mexico);  Mark R. Vaughn (Albuquerque, New Mexico);  Steven D. Knudsen (Stanley, New Mexico)
ABSTRACT A self-consuming structure is disclosed that is formed from a self-consuming composition based on an epoxy or polyurethane having fuel and/or oxidizer molecularly dispersed and/or as particulates in the epoxy or polyurethane. The composition may be used to form self-consuming structural components.
FILED Wednesday, July 17, 2013
APPL NO 13/943959
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 45/10 (20130101) Original (OR) Class

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 33/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656937 Held et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Virent, Inc. (Madison, Wisconsin)
ASSIGNEE(S) Virent, Inc. (Madison, Wisconsin)
INVENTOR(S) Andrew Held (Madison, Wisconsin);  Elizabeth Woods (Middleton, Wisconsin);  Randy Cortright (Madison, Wisconsin);  Matthew Gray (Highlands Ranch, Colorado)
ABSTRACT The present invention provides processes, methods, and systems for converting biomass-derived feedstocks to liquid fuels and chemicals. The method generally includes the reaction of a hydrolysate from a biomass deconstruction process with hydrogen and a catalyst to produce a reaction product comprising one of more oxygenated compounds. The process also includes reacting the reaction product with a condensation catalyst to produce C4+ compounds useful as fuels and chemicals.
FILED Tuesday, June 28, 2016
APPL NO 15/195596
ART UNIT 1671 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 27/04 (20130101)
C07C 29/60 (20130101)
C07C 29/132 (20130101)
C07C 29/132 (20130101)
C07C 29/132 (20130101)
C07C 29/132 (20130101)
C07C 31/12 (20130101)
C07C 31/20 (20130101)
C07C 31/125 (20130101)
C07C 41/09 (20130101)
C07C 45/59 (20130101)
C07C 45/60 (20130101) Original (OR) Class
C07C 51/377 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 3/42 (20130101)
C10G 3/52 (20130101)
C10G 2300/1014 (20130101)
C10G 2300/1018 (20130101)
C10G 2400/22 (20130101)
C10G 2400/30 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/02 (20130101)
C10L 2200/0469 (20130101)
C10L 2270/04 (20130101)
C10L 2270/023 (20130101)
C10L 2270/026 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 30/20 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657304 Benning et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Christoph Benning (East Lansing, Michigan);   Sanjaya (East Lansing, Michigan)
ABSTRACT The invention relates to genetically modified agricultural plants with increased oil content in vegetative tissues, as well as to expression systems, plant cells, seeds and vegetative tissues related thereto.
FILED Wednesday, July 10, 2013
APPL NO 13/938784
ART UNIT 1662 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8247 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657400 Swala et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Dana Ray Swala (Schenectady, New York);  Richard Scott Bourgeois (Albany, New York);  Steven Paraszczak (Clifton Park, New York);  Donald Joseph Buckley (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Dana Ray Swala (Schenectady, New York);  Richard Scott Bourgeois (Albany, New York);  Steven Paraszczak (Clifton Park, New York);  Donald Joseph Buckley (Schenectady, New York)
ABSTRACT The present techniques provide a novel electrolyzer and methods for welding components of such electrolyzers. The techniques may use conductors, such as resistance wires, placed in paths around the internal structural features and edges of the components. The conductors may be incorporated into the components during manufacture by injection molding, or other molding techniques, or may be tacked or otherwise applied to the surface of the components after manufacture. When current, a field or other excitation is applied to the conductors, the plastic surrounding the wire is melted. If this plastic is in direct contact with an adjoining component, a strong, hermetic seal may be formed between the two components, including the internal structural features.
FILED Tuesday, June 10, 2008
APPL NO 12/136383
ART UNIT 1754 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 65/342 (20130101)
B29C 65/362 (20130101)
B29C 65/3476 (20130101)
B29C 65/3632 (20130101)
B29C 65/3676 (20130101)
B29C 66/54 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/543 (20130101)
B29C 66/919 (20130101)
B29C 66/949 (20130101)
B29C 66/5414 (20130101)
B29C 66/91411 (20130101)
B29C 66/91651 (20130101)
B29C 66/91933 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2023/06 (20130101)
B29K 2023/06 (20130101)
B29K 2023/12 (20130101)
B29K 2023/12 (20130101)
B29K 2025/00 (20130101)
B29K 2025/06 (20130101)
B29K 2025/08 (20130101)
B29K 2027/12 (20130101)
B29K 2027/12 (20130101)
B29K 2063/00 (20130101)
B29K 2063/00 (20130101)
B29K 2069/00 (20130101)
B29K 2069/00 (20130101)
B29K 2071/00 (20130101)
B29K 2071/00 (20130101)
B29K 2071/12 (20130101)
B29K 2071/12 (20130101)
B29K 2077/00 (20130101)
B29K 2077/00 (20130101)
B29K 2079/08 (20130101)
B29K 2079/08 (20130101)
B29K 2079/085 (20130101)
B29K 2079/085 (20130101)
B29K 2081/04 (20130101)
B29K 2081/04 (20130101)
B29K 2081/06 (20130101)
B29K 2081/06 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 9/00 (20130101) Original (OR) Class
C25B 9/18 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/366 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49002 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657966 Litwin et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Robert Zachary Litwin (Canoga Park, California);  David Wait (Canoga Park, California);  Robert T. Lancet (Canoga Park, California)
ASSIGNEE(S) SOLARRESERVE (Santa Monica, California)
INVENTOR(S) Robert Zachary Litwin (Canoga Park, California);  David Wait (Canoga Park, California);  Robert T. Lancet (Canoga Park, California)
ABSTRACT Thermocline storage tanks for solar power systems are disclosed. A thermocline region is provided between hot and cold storage regions of a fluid within the storage tank cavity. One example storage tank includes spaced apart baffles fixed relative to the tank and arranged within the thermocline region to substantially physically separate the cavity into hot and cold storage regions. In another example, a flexible baffle separated the hot and cold storage regions and deflects as the thermocline region shifts to accommodate changing hot and cold volumes. In yet another example, a controller is configured to move a baffle within the thermocline region in response to flow rates from hot and cold pumps, which are used to pump the fluid.
FILED Wednesday, December 16, 2009
APPL NO 12/639056
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Producing or Use of Heat Not Otherwise Provided For
F24J 2/34 (20130101) Original (OR) Class

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 20/0039 (20130101)
F28D 2020/0047 (20130101)
F28D 2020/0091 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 2265/14 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/40 (20130101)
Y02E 60/142 (20130101)
Y02E 70/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658137 Harvey et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Chris Harvey (French Camp, California);  Jerry Carter (Livermore, California);  David M. Chambers (Johns Creek, Georgia)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Chris Harvey (French Camp, California);  Jerry Carter (Livermore, California);  David M. Chambers (Johns Creek, Georgia)
ABSTRACT A magnetically-induced SPME fiber actuation system includes a SPME fiber holder and a SPME fiber holder actuator, for holding and magnetically actuating a SPME fiber assembly. The SPME fiber holder has a plunger with a magnetic material to which the SPME fiber assembly is connected, and the magnetic SPME fiber holder actuator has an elongated barrel with a loading chamber for receiving the SPME fiber assembly-connected SPME fiber holder, and an external magnet which induces axial motion of the magnetic material of the plunger to extend/retract the SPME fiber from/into the protective needle of the SPME fiber assembly.
FILED Wednesday, June 18, 2014
APPL NO 14/308503
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/10 (20130101) Original (OR) Class
G01N 1/405 (20130101)
G01N 2030/009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658350 Stowe et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Security Complex and PANTEX Plant (Y-12)
NNSA Critical Mission Site
Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S) Ashley C. Stowe (Knoxville, Tennessee);  Brenden Wiggins (Oak Ridge, Tennessee);  Arnold Burger (Nashville, Tennessee)
ASSIGNEE(S) CONSOLIDATED NUCLEAR SECURITY, LLC (Oak Ridge, Tennessee);  FISK UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Ashley C. Stowe (Knoxville, Tennessee);  Brenden Wiggins (Oak Ridge, Tennessee);  Arnold Burger (Nashville, Tennessee)
ABSTRACT A radiation detection device, including: a support structure; and a chalcopyrite crystal coupled to the support structure; wherein, when the chalcopyrite crystal is exposed to radiation, a visible spectrum of the chalcopyrite crystal changes from an initial color to a modified color. The visible spectrum of the chalcopyrite crystal is changed back from the modified color to the initial color by annealing the chalcopyrite crystal at an elevated temperature below a melting point of the chalcopyrite crystal over time. The chalcopyrite crystal is optionally a 6LiInSe2 crystal. The radiation is comprised of neutrons that decrease the 6Li concentration of the chalcopyrite crystal via a 6Li(n,α) reaction. The initial color is yellow and the modified color is one of orange and red. The annealing temperature is between about 450 degrees C. and about 650 degrees C. and the annealing time is between about 12 hrs and about 36 hrs.
FILED Wednesday, June 03, 2015
APPL NO 14/729715
ART UNIT 2884 — Optics
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 11/12 (20130101)
C30B 29/46 (20130101)
C30B 33/02 (20130101)

Measurement of Nuclear or X-radiation
G01T 3/00 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/67098 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658444 O'Neill
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Nevada National Security Site (NNSS)
NNSA Critical Mission Site
Operated by Mission Support and Test Services, LLC at Las Vegas, NV (MSTS)
APPLICANT(S) National Security Technologies, LLC (Las Vegas, Nevada)
ASSIGNEE(S) National Security Technologies, LLC (Las Vegas, Nevada)
INVENTOR(S) Mary Morabito O'Neill (Santa Barbara, California)
ABSTRACT An autofocus system includes an imaging device, a lens system and a focus control actuator that is configured to change a focus position of the imaging device in relation to a stage. The electronic control unit is configured to control the focus control actuator to a plurality of predetermined focus positions, and activate the imaging device to obtain an image at predetermined positions and then apply a spatial filter to the obtained images. This generates a filtered image for the obtained images. The control unit determines a focus score for the filtered images such that the focus score corresponds to a degree of focus in the obtained images. The control unit identifies a best focus position by comparing the focus score of the filtered images, and controls the focus control actuator to the best focus position corresponding to the highest focus score.
FILED Wednesday, November 12, 2014
APPL NO 14/539962
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/367 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/23212 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658612 Spicer et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan)
ASSIGNEE(S) GM Global Technology Operations LLC (Detroit, Michigan)
INVENTOR(S) John Patrick Spicer (Plymouth, Michigan);  Wayne W. Cai (Troy, Michigan);  Debejyo Chakraborty (Novi, Michigan);  Keith Mink (Clarkston, Michigan)
ABSTRACT A vibration welding system includes vibration welding equipment having a welding horn and anvil, a host machine, a check station, and a welding robot. At least one displacement sensor is positioned with respect to one of the welding equipment and the check station. The robot moves the horn and anvil via an arm to the check station, when a threshold condition is met, i.e., a predetermined amount of time has elapsed or a predetermined number of welds have been completed. The robot moves the horn and anvil to the check station, activates the at least one displacement sensor, at the check station, and determines a status condition of the welding equipment by processing the received signals. The status condition may be one of the alignment of the vibration welding equipment and the wear or degradation of the vibration welding equipment.
FILED Tuesday, December 02, 2014
APPL NO 14/557923
ART UNIT 2127 — AI & Simulation/Modeling
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 20/10 (20130101)
B23K 20/26 (20130101)
B23K 31/12 (20130101)
B23K 2201/36 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/4065 (20130101) Original (OR) Class
G05B 2219/45146 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659145 Sayood et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Khalid Sayood (Lincoln, Nebraska);  Sam Way (Boulder, Colorado);  Ozkan Ufuk Nalbantoglu (Lincoln, Nebraska);  George Garrity (Okemos, Michigan)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska);  NamesforLife, LLC (Lansing, Michigan)
INVENTOR(S) Khalid Sayood (Lincoln, Nebraska);  Sam Way (Boulder, Colorado);  Ozkan Ufuk Nalbantoglu (Lincoln, Nebraska);  George Garrity (Okemos, Michigan)
ABSTRACT DNA sequences are analyzed using latent semantic analysis. A set of nucleotide sequences is received in which the set has a first number of sequences. A set of basis vectors is determined, in which the set has a second number of basis vectors, the second number being smaller than the first number. Each basis vector represents a specific combination of predetermined nucleotide segments. For each of the nucleotide sequences, an approximate representation of the nucleotide sequence is determined based on a combination of the basis vectors. For each pair of nucleotide sequences, a distance between the pair of nucleotide sequences is determined according the distance between the approximate representation of the pair of nucleotide sequences. The set of nucleotide sequences are classified based on the distances between the pairs of nucleotide sequences.
FILED Tuesday, July 30, 2013
APPL NO 13/954925
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electric Digital Data Processing
G06F 19/22 (20130101) Original (OR) Class
G06F 19/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659205 Demos
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Stavros Demos (Livermore, California)
ABSTRACT Systems and methods are disclosed for obtaining at least a pair of biometric traits of a person and without contact with the person. In one embodiment a system is disclosed which makes use of a plurality of illumination modules and an imaging module, where a single image is acquired with a color encoded imaging sensor. Parallel and orthogonally polarized images are obtained by at least one sensor of the imaging module from illuminations produced by the illumination modules. A processing subsystem uses mathematical applied operations between the acquired images to selectively produce at least one image of at least one specific biometric trait, such as a finger print, a palm print, a finger-vein, a palm vein, or hand geometry. The biometric trait can be subsequently used for biometric verification and identification.
FILED Monday, June 09, 2014
APPL NO 14/299867
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00013 (20130101) Original (OR) Class
G06K 9/00885 (20130101)
G06K 9/00892 (20130101)
G06K 9/2018 (20130101)
G06K 2009/00932 (20130101)

Pictorial Communication, e.g Television
H04N 5/2354 (20130101)
H04N 7/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659706 Qiu et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Jizheng Qiu (West Lebanon, New Hampshire);  Charles R. Sullivan (West Lebanon, New Hampshire)
ABSTRACT A method of forming a radially anisotropic toroidal magnetic core includes providing apparatus having a first magnet for providing a radial magnetic field extending across a cavity from an axial spindle to a surrounding second magnetic element, placing a substrate in the cavity, the substrate having a hole fitting around the head of the spindle; and sputter-depositing a film of ferromagnetic material onto the substrate. In an embodiment, the spindle is magnetically coupled to a first pole of the first magnet, the second magnetic element is coupled to a second pole of the first magnet, and a thermally conductive, nonmagnetic, insert separates the spindle and the second magnetic element.
FILED Monday, September 24, 2012
APPL NO 14/346659
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/458 (20130101)
C23C 16/4583 (20130101)
C23C 16/4584 (20130101)

Static Stores
G11C 19/08 (20130101)
G11C 19/0808 (20130101)
G11C 19/0816 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 3/02 (20130101)
H01F 7/02 (20130101)
H01F 7/0273 (20130101)
H01F 41/02 (20130101) Original (OR) Class
H01F 41/18 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49075 (20150115)
Y10T 29/49076 (20150115)
Y10T 29/49078 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659797 Burckel et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) David Bruce Burckel (Albuquerque, New Mexico);  Robert L. Jarecki, Jr. (Albuquerque, New Mexico);  Patrick Sean Finnegan (Albuquerque, New Mexico)
ABSTRACT Wafer scale oblique angle etching of a semiconductor substrate is performed in a conventional plasma etch chamber by using a fixture that supports a multiple number of separate Faraday cages. Each cage is formed to include an angled grid surface and is positioned such that it will be positioned over a separate one of the die locations on the wafer surface when the fixture is placed over the wafer. The presence of the Faraday cages influences the local electric field surrounding each wafer die, re-shaping the local field to be disposed in alignment with the angled grid surface. The re-shaped plasma causes the reactive ions to follow a linear trajectory through the plasma sheath and angled grid surface, ultimately impinging the wafer surface at an angle. The selected geometry of the Faraday cage angled grid surface thus determines the angle at with the reactive ions will impinge the wafer.
FILED Wednesday, September 17, 2014
APPL NO 14/489362
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/3065 (20130101)
H01L 21/3085 (20130101)
H01L 21/67069 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660026 Okandan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Murat Okandan (Edgewood, New Mexico);  Bruce L. Draper (Albuquerque, New Mexico);  Paul J. Resnick (Albuquerque, New Mexico)
ABSTRACT There is provided an electronic device and a method for its manufacture. The device comprises an elongate silicon nanowire less than 0.5 μm in cross-sectional dimensions and having a hexagonal cross-sectional shape due to annealing-induced energy relaxation. The method, in examples, includes thinning the nanowire through iterative oxidation and etching of the oxidized portion.
FILED Thursday, November 17, 2016
APPL NO 15/354196
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/0675 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/306 (20130101)
H01L 21/3065 (20130101)
H01L 29/0669 (20130101) Original (OR) Class
H01L 29/0673 (20130101)
H01L 29/0847 (20130101)
H01L 29/1037 (20130101)
H01L 29/7853 (20130101)
H01L 29/42376 (20130101)
H01L 29/42392 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660125 Plesniak et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Adam P. Plesniak (Huntington Beach, California);  John C. Hall (Rancho Palos Verdes, California)
ABSTRACT A method of making a solar concentrator may include forming a receiving wall having an elongated wall, a first side wall and a second side wall; attaching the first side wall and the second side wall to a reflecting wall to form a housing having an internal volume with an opening; forming a lip on the receiving wall and the reflecting wall; attaching a cover to the receiving wall and the reflecting wall at the lip to seal the opening into the internal volume, thereby creating a rigid structure; and mounting at least one receiver having at least one photovoltaic cell on the elongated wall to receive solar radiation entering the housing and reflected by the receiving wall, the receiver having an axis parallel with a surface normal of the photovoltaic cell, such that the axis is disposed at a non-zero angle relative to the vertical axis of the opening.
FILED Tuesday, January 27, 2015
APPL NO 14/606316
ART UNIT 1757 — Semiconductors/Memory
CURRENT CPC
Producing or Use of Heat Not Otherwise Provided For
F24J 2/06 (20130101)
F24J 2/08 (20130101)
F24J 2/08 (20130101)
F24J 2/10 (20130101)
F24J 2/12 (20130101)
F24J 2/14 (20130101)
F24J 2/50 (20130101)
F24J 2/464 (20130101)
F24J 2/1057 (20130101)
F24J 2/5243 (20130101)
F24J 2002/1085 (20130101)
F24J 2002/4692 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/052 (20130101)
H01L 31/052 (20130101)
H01L 31/054 (20141201)
H01L 31/0547 (20141201) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/40 (20130101)
Y02E 10/45 (20130101)
Y02E 10/52 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49355 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660241 Wang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sharp Laboratories of America, Inc. (Camas, Washington)
ASSIGNEE(S) Sharp Laboratories of America, Inc. (Camas, Washington)
INVENTOR(S) Long Wang (Vancouver, Washington);  Yuhao Lu (Vancouver, Washington);  Jong-Jan Lee (Camas, Washington);  Sean Vail (Vancouver, Washington)
ABSTRACT A method is provided for forming a sodium-containing particle electrolyte structure. The method provides sodium-containing particles (e.g., NASICON), dispersed in a liquid phase polymer, to form a polymer film with sodium-containing particles distributed in the polymer film. The liquid phase polymer is a result of dissolving the polymer in a solvent or melting the polymer in an extrusion process. In one aspect, the method forms a plurality of polymer film layers, where each polymer film layer includes sodium-containing particles. For example, the plurality of polymer film layers may form a stack having a top layer and a bottom layer, where with percentage of sodium-containing particles in the polymer film layers increasing from the bottom layer to the top layer. In another aspect, the sodium-containing particles are coated with a dopant. A sodium-containing particle electrolyte structure and a battery made using the sodium-containing particle electrolyte structure are also presented.
FILED Thursday, March 06, 2014
APPL NO 14/198755
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 17/02 (20130101)
C01B 19/02 (20130101)
C01B 25/003 (20130101)
C01B 31/00 (20130101)
C01B 33/021 (20130101)

Ammonia; Cyanogen; Compounds Thereof
C01C 3/12 (20130101)

Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium
C01D 1/02 (20130101)
C01D 15/02 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/14 (20130101)
H01M 2/1653 (20130101)
H01M 2/1686 (20130101) Original (OR) Class
H01M 4/04 (20130101)
H01M 4/38 (20130101)
H01M 4/049 (20130101)
H01M 4/56 (20130101)
H01M 4/58 (20130101)
H01M 4/131 (20130101)
H01M 4/133 (20130101)
H01M 4/134 (20130101)
H01M 4/136 (20130101)
H01M 4/381 (20130101)
H01M 4/382 (20130101)
H01M 4/387 (20130101)
H01M 4/0404 (20130101)
H01M 4/0416 (20130101)
H01M 4/0452 (20130101)
H01M 4/0471 (20130101)
H01M 4/485 (20130101)
H01M 4/0495 (20130101)
H01M 4/0497 (20130101)
H01M 4/505 (20130101)
H01M 4/587 (20130101)
H01M 4/628 (20130101)
H01M 4/1391 (20130101)
H01M 4/1395 (20130101)
H01M 4/1397 (20130101)
H01M 4/5825 (20130101)
H01M 10/052 (20130101)
H01M 10/054 (20130101)
H01M 10/056 (20130101)
H01M 10/0525 (20130101)
H01M 10/0565 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/0042 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49108 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660265 Visco et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) PolyPlus Battery Company (Berkeley, California)
ASSIGNEE(S) POLYPLUS BATTERY COMPANY (Berkeley, California)
INVENTOR(S) Steven J. Visco (Berkeley, California);  Nikolay Goncharenko (Walnut Creek, California);  Vitaliy Nimon (San Francisco, California);  Alexei Petrov (Walnut Creek, California);  Yevgeniy S. Nimon (Danville, California);  Lutgard C. De Jonghe (Lafayette, California);  Bruce D. Katz (Moraga, California);  Valentina Loginova (Walnut Creek, California)
ABSTRACT Lithium sulfur battery cells that use water as an electrolyte solvent provide significant cost reductions. Electrolytes for the battery cells may include water solvent for maintaining electroactive sulfur species in solution during cell discharge and a sufficient amount of a cycle life-enhancing compound that facilitates charging at the cathode. The combination of these two components enhances one or more of the following cell attributes: energy density, power density and cycle life. For instance, in applications where cost per Watt-Hour (Wh) is paramount, such as grid storage and traction applications, the use of an aqueous electrolyte in combination with inexpensive sulfur as the cathode active material can be a key enabler for the utility and automotive industries, for example, providing a cost effective and compact solution for load leveling, electric vehicles and renewable energy storage. Sulfur cathodes, and methods of fabricating lithium sulfur cells, in particular for loading lithium sulfide into the cathode structures, provide further advantages.
FILED Friday, March 13, 2015
APPL NO 14/657695
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/40 (20130101)
H01M 4/38 (20130101)
H01M 4/74 (20130101)
H01M 4/382 (20130101)
H01M 4/386 (20130101)
H01M 4/405 (20130101)
H01M 4/485 (20130101)
H01M 4/587 (20130101)
H01M 4/661 (20130101)
H01M 4/663 (20130101)
H01M 4/667 (20130101)
H01M 4/806 (20130101)
H01M 4/808 (20130101)
H01M 4/5815 (20130101) Original (OR) Class
H01M 10/36 (20130101)
H01M 2300/0002 (20130101)
H01M 2300/0014 (20130101)
H01M 2300/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660268 Song et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sharp Laboratories of America, Inc. (Camas, Washington)
ASSIGNEE(S) Sharp Laboratories of America, Inc. (Camas, Washington)
INVENTOR(S) Jie Song (Vancouver, Washington);  Yuhao Lu (Camas, Washington);  Xin Zhao (Vancouver, Washington)
ABSTRACT An alkali-ion battery is provided with a transition metal cyanometallate (TMCM) sheet cathode and a non-alkaline metal anode. The fabrication method mixes TMCM powders, conductive additives, and a polytetrafluoroethylene binder with a solution containing water, forming a wet paste. The wet paste is formed into a free-standing sheet of cathode active material, which is laminated to a cathode current collector, forming a cathode electrode. The free-standing sheet of cathode active material has a thickness typically in the range of 100 microns to 2 millimeters. The cathode electrode is assembled with a non-alkaline metal anode electrode and an ion-permeable membrane interposed between the cathode electrode and anode electrode, forming an assembly. The assembly is dried at a temperature of greater than 100 degrees C. The dried assembly is then inserted into a container (case) and electrolyte is added. Thick anodes made from free-standing sheets of active material can be similarly formed.
FILED Friday, October 30, 2015
APPL NO 14/928559
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Ammonia; Cyanogen; Compounds Thereof
C01C 3/11 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/162 (20130101)
H01M 2/1626 (20130101)
H01M 2/1646 (20130101)
H01M 4/56 (20130101)
H01M 4/136 (20130101)
H01M 4/381 (20130101)
H01M 4/387 (20130101)
H01M 4/622 (20130101)
H01M 4/623 (20130101)
H01M 4/1397 (20130101)
H01M 4/5825 (20130101) Original (OR) Class
H01M 10/054 (20130101)
H01M 10/0585 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660299 Xu et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Southwest Research Institute (San Antonio, Texas)
ASSIGNEE(S) SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas)
INVENTOR(S) Jeff Qiang Xu (San Antonio, Texas);  Joe Steiber (Spring Branch, Texas);  Craig M. Wall (San Antonio, Texas);  Robert Smith (Fair Lawn, New Jersey);  Cheuk Ng (San Antonio, Texas)
ABSTRACT A method and system for strain-based estimation of the state of health of a battery, from an initial state to an aged state, is provided. A strain gauge is applied to the battery. A first strain measurement is performed on the battery, using the strain gauge, at a selected charge capacity of the battery and at the initial state of the battery. A second strain measurement is performed on the battery, using the strain gauge, at the selected charge capacity of the battery and at the aged state of the battery. The capacity degradation of the battery is estimated as the difference between the first and second strain measurements divided by the first strain measurement.
FILED Tuesday, December 10, 2013
APPL NO 14/102197
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/3679 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/42 (20130101) Original (OR) Class
H01M 10/48 (20130101)
H01M 10/4285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660311 Visco et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Steven J. Visco (Berkeley, California);  Yevgeniy S. Nimon (Danville, California);  Lutgard C. De Jonghe (Lafayette, California);  Alexei Petrov (Walnut Creek, California);  Nikolay Goncharenko (Walnut Creek, California)
ASSIGNEE(S) POLYPLUS BATTERY COMPANY (Berkeley, California)
INVENTOR(S) Steven J. Visco (Berkeley, California);  Yevgeniy S. Nimon (Danville, California);  Lutgard C. De Jonghe (Lafayette, California);  Alexei Petrov (Walnut Creek, California);  Nikolay Goncharenko (Walnut Creek, California)
ABSTRACT Aqueous Li/Air secondary battery cells are configurable to achieve high energy density and prolonged cycle life. The cells include a protected a lithium metal or alloy anode and an aqueous catholyte in a cathode compartment. The aqueous catholyte comprises an evaporative-loss resistant and/or polyprotic active compound or active agent that partakes in the discharge reaction and effectuates cathode capacity for discharge in the acidic region. This leads to improved performance including one or more of increased specific energy, improved stability on open circuit, and prolonged cycle life, as well as various methods, including a method of operating an aqueous Li/Air cell to simultaneously achieve improved energy density and prolonged cycle life.
FILED Friday, August 17, 2012
APPL NO 13/588911
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 12/08 (20130101) Original (OR) Class
H01M 2300/0005 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/128 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660520 Perreault et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David J. Perreault (Andover, Massachusetts);  Seungbum Lim (Cambridge, Massachusetts);  David M. Otten (Newton, Massachusetts)
ABSTRACT A power converter circuit rectifies a line voltage and applies the rectified voltage to a stack of capacitors. Voltages on the capacitors are coupled to a plurality of regulating converters to be converted to regulated output signals. The regulated output signals are combined and converted to a desired DC output voltage of the power converter. Input currents of the regulating converters are modulated in a manner that enhances the power factor of the power converter.
FILED Tuesday, April 08, 2014
APPL NO 14/758033
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/4208 (20130101)
H02M 1/4225 (20130101)
H02M 1/4241 (20130101) Original (OR) Class
H02M 3/158 (20130101)
H02M 3/33569 (20130101)
H02M 7/06 (20130101)
H02M 2001/007 (20130101)
H02M 2001/0074 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 70/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09661733 Elizondo-Decanini
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Juan M. Elizondo-Decanini (Albuquerque, New Mexico)
ABSTRACT Switching devices are provided. The switching devices include an input electrode, having a main electrode and a trigger electrode, and an output electrode. The main electrode and the trigger electrode are separated from the output electrode by a main gap and a trigger gap, respectively. During operation, the trigger electrode compresses and amplifies a trigger voltage signal causing the trigger electrode to emit a pulse of energy. This pulse of energy form plasma near the trigger electrode, either by arcing across the trigger gap, or by arcing from the trigger electrode to the main electrode. This plasma decreases the breakdown voltage of the main gap. Simultaneously, or near simultaneously, a main voltage signal propagates through the main electrode. The main voltage signal emits a main pulse of energy that arcs across the main gap while the plasma formed by the trigger pulse is still present.
FILED Friday, September 30, 2016
APPL NO 15/281991
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/48 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09661737 Trbojevic
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Dejan Trbojevic (Wading River, New York)
ASSIGNEE(S) The United States of America, as represented by the Department of Energy (Washington, District of Columbia)
INVENTOR(S) Dejan Trbojevic (Wading River, New York)
ABSTRACT A non-scaling fixed field alternating gradient accelerator includes a racetrack shape including a first straight section connected to a first arc section, the first arc section connected to a second straight section, the second straight section connected to a second arc section, and the second arc section connected to the first straight section; an matching cells configured to match particle orbits between the first straight section, the first arc section, the second straight section, and the second arc section. The accelerator includes the matching cells and an associated matching procedure enabling the particle orbits at varying energies between an arc section and a straight section in the racetrack shape.
FILED Friday, May 23, 2014
APPL NO 14/285706
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 13/08 (20130101)
H05H 13/085 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 09655553 Plumley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) John B. Plumley (Albuquerque, New Mexico);  Erin D. Milligan (Placitas, New Mexico);  Marek Osinski (Albuquerque, New Mexico)
ABSTRACT The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.
FILED Thursday, September 10, 2015
APPL NO 14/850221
ART UNIT 3777 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1455 (20130101) Original (OR) Class
A61B 5/1459 (20130101)
A61B 5/4058 (20130101)
A61B 5/6852 (20130101)
A61B 5/6877 (20130101)
A61B 5/14735 (20130101)
A61B 2562/0233 (20130101)
A61B 2562/0285 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/588 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09655679 Desai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION (College Park, Maryland)
ASSIGNEE(S) University of Maryland (College Park, Maryland)
INVENTOR(S) Jaydev P. Desai (Bethesda, Maryland);  Elif Ayvali (College Park, Maryland)
ABSTRACT A steerable probe having high-power-density actuators positioned at joints along the length of the probe. The actuators are moveable about and between a straight position and a curved position in response to selective actuation.
FILED Wednesday, May 01, 2013
APPL NO 13/875204
ART UNIT 3779 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/3417 (20130101)
A61B 17/3421 (20130101)
A61B 19/201 (20130101) Original (OR) Class
A61B 90/11 (20160201)
A61B 90/39 (20160201)
A61B 2017/003 (20130101)
A61B 2017/00867 (20130101)
A61B 2034/2055 (20160201)
A61B 2090/3735 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656001 Mayes et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Sarah Mayes (Austin, Texas);  Christine E. Schmidt (Gainesville, Florida)
ABSTRACT A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
FILED Monday, July 20, 2015
APPL NO 14/803258
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/192 (20130101)
A61K 31/195 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/16 (20130101)
A61L 31/041 (20130101) Original (OR) Class
A61L 31/041 (20130101)
A61L 31/041 (20130101)
A61L 31/145 (20130101)
A61L 31/148 (20130101)
A61L 2300/43 (20130101)
A61L 2300/62 (20130101)
A61L 2300/414 (20130101)

Compositions of Macromolecular Compounds
C08L 5/04 (20130101)
C08L 5/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656262 Paliwal et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Saurabh Paliwal (Mountain View, California);  Zhizhong Yin (Timonium, Maryland);  Raymond Cheong (Timonium, Maryland)
ASSIGNEE(S) EUVEDA BIOSCIENCES, INC. (Timonium, Maryland)
INVENTOR(S) Saurabh Paliwal (Mountain View, California);  Zhizhong Yin (Timonium, Maryland);  Raymond Cheong (Timonium, Maryland)
ABSTRACT Microfluidic devices have been developed to perform a range of high-throughput biochemical and cell-based assays over recent years. A design for a microfluidic device has been developed that resembles a microtiter plate, by placing the test chambers (each test chamber contains cells) and top-loading drug inlets (at least one per test chamber) in a grid according to the ANSI/SBS standards, yet offers the miniaturization and fluid handling advantages of microfluidics. This ensures that the device design is compatible with fluid handling and imaging equipment already in use for drug screening. A range of topologies have been determined that allow placement of various elements of this microfluidic network within the grid alignment constraints. A resistance equalization methodology has also been developed to reduce variability across assays run in different chambers of the microfluidic device. Additionally, it offers orders of magnitude miniaturization over multiwell plates, and potentially more reliable fluid handling.
FILED Tuesday, June 10, 2014
APPL NO 14/301319
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502738 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2300/0829 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0874 (20130101)
B01L 2300/0883 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0655 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0018 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656414 Fourkas et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) John T. Fourkas (Bethesda, Maryland);  Christopher N. LaFratta (Brighton, Massachusetts)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) John T. Fourkas (Bethesda, Maryland);  Christopher N. LaFratta (Brighton, Massachusetts)
ABSTRACT The present invention relates to microfluidic devices that comprise a 3-D microfluidic network of microchannels of arbitrary complexity and to a method for fabricating such devices. In particular, the invention relates to a method of forming microfluidic devices having 3-D microfluidic networks that contain open or closed loop microchannels using a single-step molding process without the need for layer-by-layer fabrication, and to the resultant microfluidic devices. The networks of such microfluidic devices may comprise one or more microchannel circuits which may be discrete or interconnected.
FILED Monday, February 24, 2014
APPL NO 14/187673
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 33/405 (20130101)
B29C 33/3857 (20130101)
B29C 39/006 (20130101)
B29C 39/36 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/756 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/2224 (20150401)
Y10T 137/8593 (20150401)
Y10T 137/85938 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656900 Jain et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Himanshu Jain (Bethlehem, Pennsylvania);  Hassan Mohamady Mohamed Moawad (Bethlehem, Pennsylvania)
ASSIGNEE(S) Lehigh University (Bethlehem, Pennsylvania)
INVENTOR(S) Himanshu Jain (Bethlehem, Pennsylvania);  Hassan Mohamady Mohamed Moawad (Bethlehem, Pennsylvania)
ABSTRACT Provided herein are methods for preparing nano-macroporous glass articles, such as bioscaffolds, from starting materials such as phosphosilicate glasses made by melt-quench methods, mixed with a soluble pore former such as a sugar, followed by steps of dissolving, heating, and leaching to yield a glass composition having a highly interconnected system of both macropores and large scale nanoporosity.
FILED Thursday, January 26, 2012
APPL NO 13/358858
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Manufacture, Shaping, or Supplementary Processes
C03B 19/06 (20130101)
C03B 32/02 (20130101) Original (OR) Class

Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 11/005 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/268 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658162 Wickramasinghe
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) H. Kumar Wickramasinghe (Irvine, California)
ABSTRACT An apparatus and method for measuring amplitude and/or phase of a molecular vibration uses a polarization modulated pump beam and a stimulating Stokes beam on a probe of a scanning probe microscope to detect a Raman scattered Stokes beam from the sample. The detected Raman scattered Stokes beam is used to derive at least one of the amplitude and the phase of the molecular vibration.
FILED Monday, March 09, 2015
APPL NO 14/642655
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/44 (20130101)
G01J 3/45 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/65 (20130101) Original (OR) Class
G01N 2021/655 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 30/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658206 Siwy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Zuzanna S. Siwy (Irvine, California);  Kenneth J. Shea (Irvine, California);  Ken Healy (Auburn, Alabama);  Laura Michele Innes (Cerritos, California);  Matthew Schiel (Irvine, California);  Matthew Pevarnik (Irvine, California)
ABSTRACT A method for multiplex characterization of individual particles by their size, shape, mechanical properties (deformability), and chemical affinity to recognition agents. The analysis can be performed from concentrated solutions. The method detects transient sticking of particles in the pore and points to its location along a pore axis. If a pore is decorated with a recognition agent for an analyte present in a solution, it is possible to distinguish specific binding at the place of the recognition agent, and non-specific adsorption of the analyte. The method confirms whether any individual particle or hydrogel completely translocates the pore and allows unambiguous detection and characterization of multiple particles or hydrogels in the pore, which would previously corrupt the results, so that higher analyte concentrations can be used for faster analysis. High aspect ratio of the pores (ratio of pore length and diameter) together with the pattern of ion current pulses also allow passage of the same particle or cell multiple times without letting the cell exit the pore.
FILED Friday, May 09, 2014
APPL NO 14/274404
ART UNIT 1759 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1218 (20130101)
G01N 27/44791 (20130101)
G01N 33/48721 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658443 Broxton et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Michael J. Broxton (San Francisco, California);  Marc S. Levoy (Stanford, California);  Noy Cohen (Stanford, California);  Logan Grosenick (San Francisco, California);  Samuel Yang (Stanford, California);  Karl A. Deisseroth (Stanford, California)
ABSTRACT Images are detected in a manner that addresses various challenges as discussed herein. As may be consistent with one or more embodiments, aspects are directed to an apparatus having sets of photosensors that detect light rays received at different angles from a specimen via a microlens array, with the light rays detected by each set of photosensors representing an aliased view of the specimen. An output indicative of aliased views of the specimen is provided. Certain embodiments further include a logic circuit that processes the output and generates a deconvolved volume image by combining aliased views of the specimen as detected by the photosensors.
FILED Thursday, March 13, 2014
APPL NO 14/209777
ART UNIT 2878 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/0006 (20130101)
G02B 21/367 (20130101) Original (OR) Class
G02B 27/0075 (20130101)

Pictorial Communication, e.g Television
H04N 5/225 (20130101)
H04N 13/0232 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658510 Kippelen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Bernard Kippelen (Atlanta, Georgia);  Canek Fuentes-Hernandez (Atlanta, Georgia);  James June Fan Hsu (Atlanta, Georgia)
ABSTRACT An optical device capable of an ultrafast and large change of its reflection or absorption coefficient upon being excited by an ultrafast optical pulse with wavelength in the visible, near-infrared, or infrared spectral regions. The optical device includes, in sequential order, a first thick metallic layer, a first dielectric layer, a second thin metallic layer, and a second dielectric layer. The optical device acts as a nonlinear mirror that presents a large reflectance at low irradiance and a low reflectance at large irradiance. The optical device can further act as a nonlinear mirror that presents a linear and nonlinear reflectance with a large angular bandwidth.
FILED Friday, December 20, 2013
APPL NO 14/764100
ART UNIT 2872 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/17 (20130101)
G02F 1/19 (20130101)
G02F 1/21 (20130101) Original (OR) Class
G02F 1/0126 (20130101)
G02F 1/355 (20130101)
G02F 1/3523 (20130101)
G02F 2001/211 (20130101)
G02F 2203/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659189 Lee et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Wenke Lee (Atlanta, Georgia);  Alexandra Boldyreva (Atlanta, Georgia);  Chung Pak Ho (Atlanta, Georgia);  Billy Lau (Atlanta, Georgia);  Chengyu Song (Atlanta, Georgia)
ABSTRACT The disclosed technology includes techniques for improving data privacy in mobile communications over public cloud services. According to certain implementations, a novel conceptual layer may be interposed between the “application” layer and the “user” layer. In some implementations, the conceptual layer may be at least partially embodied by a transparent window or pane overlaid on top of existing app graphical user interfaces to: (1) intercept plaintext user input before transforming the input and feeding it to an underlying app; and (2) reverse transform output data from the app before displaying the plaintext data to the user. Accordingly, the conceptual layer may serve as a protective layer while preserving the original application workflow and look-and-feel.
FILED Tuesday, October 14, 2014
APPL NO 14/513680
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/6263 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0435 (20130101)

Wireless Communication Networks
H04W 12/00 (20130101)
H04W 12/02 (20130101)
H04W 88/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659210 De la Torre et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Fernando De la Torre (Pittsburgh, Pennsylvania);  Xuehan Xiong (Pittsburgh, Pennsylvania)
ABSTRACT The present invention relates to a system for detecting and tracking facial features in images and can be used in conjunction with a camera. Given a camera, the system will detect facial landmarks in images. The present invention includes software for real time, accurate facial feature detection and tracking in unconstrained images and videos. The present invention is better, more robust and faster than existing approaches and can be implemented very efficiently allowing real-time processing, even on low-power devices, such as mobile phones.
FILED Tuesday, January 13, 2015
APPL NO 14/596148
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00241 (20130101) Original (OR) Class
G06K 9/00268 (20130101)

Image Data Processing or Generation, in General
G06T 7/73 (20170101)
G06T 2207/10004 (20130101)
G06T 2207/20081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659351 Aliaga et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Daniel Gerardo Aliaga (West Lafayette, Indiana);  Carlos Roberto Montalto Cruz (Seattle, Washington);  Ignacio Garcia Dorado (West Lafayette, Indiana)
ABSTRACT A method to generate an output image that improves observation of a target image viewed on a medium by an optical system is disclosed. The method includes receiving at least one target image by a processing system, receiving at least one parameter by the processing system, defining an error signal associated with the difference between calculated optical system observation of intermediate images and the at least one target image, minimizing the error signal, and generating an output image associated with the intermediate image having the minimized error.
FILED Thursday, March 12, 2015
APPL NO 14/656681
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/00 (20130101)
A61B 3/032 (20130101)

Image Data Processing or Generation, in General
G06T 5/001 (20130101) Original (OR) Class
G06T 5/003 (20130101)
G06T 2207/20056 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659372 Nguyen et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Truong Nguyen (San Diego, California);  Ho Chan (La Jolla, California);  Ramsin Khoshabeh (San Diego, California)
ABSTRACT A method for disparity estimation of stereo video data receives a sequence of frames of stereo video data. Image-based disparity estimation is initially conducted on a frame-by-frame basis to produce initial disparity estimates. A plurality of initial disparity estimates is grouped into a space-time volume. Disparity error is reduced in the space-time volume to refine the initial disparity estimates.
FILED Tuesday, May 14, 2013
APPL NO 14/389873
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0022 (20130101) Original (OR) Class
G06T 2207/10021 (20130101)

Pictorial Communication, e.g Television
H04N 13/025 (20130101)
H04N 13/0048 (20130101)
H04N 13/0488 (20130101)
H04N 2013/0081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660168 Hall et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Matthew J. Hall (Austin, Texas);  Li Shi (Austin, Texas)
ABSTRACT A thermoelectric power generator for converting thermal energy into electrical energy. The thermoelectric power generator includes a heat exchanger configured to extract thermal energy from an exhaust gas stream. The heat exchanger includes fins in contact with a boundary of the heat exchanger, where the fins are directly connected to a first set of thermoelectric modules. A second set of thermoelectric modules are directly connected to the boundary of the heat exchanger. The first and second sets of thermoelectric modules are configured to convert the thermal energy to electrical energy. By eliminating the metal wall that previously existed between the thermoelectric modules and the fins, the thermoelectric power generator improves the heat transfer between the exhaust gas and the thermoelectric modules, eliminates the thermal fatigue failures at the bond between the metal wall and the thermoelectric modules as well as allows for a higher density of thermoelectric modules.
FILED Thursday, October 02, 2014
APPL NO 14/505068
ART UNIT 1757 — Semiconductors/Memory
CURRENT CPC
Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines
F01N 5/025 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/30 (20130101)
H01L 35/32 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660416 Kumar et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) LEHIGH UNIVERSITY (Bethlehem, Pennsylvania)
ASSIGNEE(S) Lehigh University (Bethlehem, Pennsylvania)
INVENTOR(S) Sushil Kumar (Center Valley, Pennsylvania);  Chongzhao Wu (Bethlehem, Pennsylvania)
ABSTRACT A distributed antenna-coupling feedback scheme and specially designed distributed feedback (DFB) metallic cavity and grating for laser application and in particular to plasmonic lasers ensuring a predesigned phase condition such that a mode traveling inside a waveguide is coupled/phase-locked to a mode traveling on the top metal improving the beam quality of the laser.
FILED Wednesday, December 30, 2015
APPL NO 14/984652
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/12 (20130101) Original (OR) Class
H01S 5/1046 (20130101)
H01S 5/3402 (20130101)
H01S 2302/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660995 Reiter et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) Michael Kendrick Reiter (Chapel Hill, North Carolina);  Apu Chandrasen Kapadia (Bloomington, Indiana);  Alana Libonati (Carrboro, North Carolina)
ABSTRACT The subject matter described herein includes methods, systems, and computer readable media for combating mobile device theft with user notarization. One method includes providing a supplicant video notarization system application executable on a supplicant device for initiating an interactive video call between a supplicant and a notary as a condition to the supplicant accessing a protected electronic resource. The method further includes providing a notary video notarization system application executable on a notary device through which the notary receives the interactive video call and interacts with the supplicant via the interactive video call to confirm the identity of the supplicant and that video of the supplicant provided in the call is live.
FILED Thursday, February 20, 2014
APPL NO 14/769160
ART UNIT 2438 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/31 (20130101)
G06F 21/88 (20130101)
G06F 21/6245 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/10 (20130101) Original (OR) Class
H04L 63/0428 (20130101)

Pictorial Communication, e.g Television
H04N 7/141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09661051 Panwar
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Shivendra Panwar (Freehold, New Jersey)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Shivendra Panwar (Freehold, New Jersey)
ABSTRACT Video streaming applications are a major contributor to the recent dramatic rise of data traffic in cellular networks. Mobile users in a cellular network often experience fluctuating data rates, which might affect the quality of video they view in a streaming service. Although replacing such video streaming services with video downloading/renting services could potentially allow such mobile users to enjoy consistently higher quality videos, such services typically cost a lot more than video streaming services because of legal copyright pricing and management issues. By downloading enhancement layers but streaming base layers of the content, mobile users can enjoy download-quality videos with a service (legally) classified as a streaming service.
FILED Monday, September 28, 2015
APPL NO 14/867503
ART UNIT 2458 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 65/80 (20130101)
H04L 65/604 (20130101)
H04L 65/607 (20130101) Original (OR) Class
H04L 65/4084 (20130101)
H04L 67/02 (20130101)
H04L 67/42 (20130101)
H04L 67/2842 (20130101)
H04L 69/02 (20130101)

Wireless Communication Networks
H04W 84/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 09655525 Lee
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Salutron, Inc. (Fremont, California)
ASSIGNEE(S) SALUTRON INC. (Newark, California)
INVENTOR(S) Yong Jin Lee (Seoul, South Korea)
ABSTRACT Described herein are user-wearable devices that include an optical sensor, and methods for use therewith. In certain embodiments, an optical sensor of a user-wearable device (e.g., a wrist-worn device) is used to detect blue light that is incident on the optical sensor and to produce a blue light detection signal indicative thereof, and thus, indicative of the response of the user's intrinsically photosensitive Retinal Ganglion Cells (ipRGCs). In dependence on the blue light detection signal, there is a determination of a metric indicative of an amount of blue light detected by the optical sensor. The metric is compared to a corresponding threshold, and a user notification is triggered in dependence on results of the comparing, wherein the user notification informs a person wearing the user-wearable device to adjust their exposure to light.
FILED Wednesday, March 18, 2015
APPL NO 14/661856
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0075 (20130101) Original (OR) Class
A61B 5/0205 (20130101)
A61B 5/681 (20130101)
A61B 5/1118 (20130101)
A61B 5/02416 (20130101)
A61B 5/4857 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09656426 Snyder et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
NASA Shared Services Center (NSSC)
APPLICANT(S) MADE IN SPACE, INC. (Moffett Field, California)
ASSIGNEE(S) MADE IN SPACE, INC. (Moffett Field, California)
INVENTOR(S) Michael Snyder (Mountain View, California);  Jason Dunn (Mountain View, California);  Michael Chen (Mountain View, California);  Aaron Kemmer (Mountain View, California);  Noah Paul-Gin (San Fransisco, California);  Matthew Napoli (Sunnyvale, California);  Eddie Gonzalez (San Fransisco, California);  Michael Pless (Lodi, California)
ABSTRACT Additive manufacturing devices operable in various external force environments are disclosed. In an aspect, an additive manufacturing device operable in microgravity is disclosed. In other aspects, devices which are operable in high-vibration environments or varying external force environments are disclosed. Additive manufacturing devices herein may produce parts from metal, polymer, or other feedstocks.
FILED Monday, December 14, 2015
APPL NO 14/968112
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Separation
B01D 45/14 (20130101)
B01D 46/0032 (20130101)
B01D 46/46 (20130101)
B01D 46/442 (20130101)
B01D 46/444 (20130101)
B01D 46/448 (20130101)
B01D 50/002 (20130101)

Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 11/01 (20130101)
B22D 11/10 (20130101)
B22D 11/16 (20130101)
B22D 23/00 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 67/0055 (20130101)
B29C 67/0059 (20130101)
B29C 67/0074 (20130101)
B29C 67/0081 (20130101)
B29C 67/0085 (20130101) Original (OR) Class
B29C 67/0088 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/00 (20141201)
B33Y 50/02 (20141201)
B33Y 99/00 (20141201)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657251 Richmond et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Robert Chaffee Richmond (Madison, Alabama);  Harry F. Schramm, Jr. (Winchester, Tennessee);  Francis G. Defalco (Houston, Texas)
ABSTRACT A wear and/or friction reducing additive for a lubricating fluid in which the additive is a combination of a moderately hydrophilic single-phase compound and an anti-wear and/or anti-friction aqueous salt solution. The aqueous salt solution produces a coating on boundary layer surfaces. The lubricating fluid can be an emulsion-free hydrophobic oil, hydraulic fluid, antifreeze, water, or a water-based lubricant. Preferably, the moderately hydrophilic single-phase compound is sulfonated castor oil and the aqueous salt solution additionally contains boric acid and zinc oxide. The emulsions produced by the aqueous salt solutions, the moderately hydrophilic single-phase compounds, or the combination thereof provide targeted boundary layer organizers that significantly enhance the anti-wear and/or anti-friction properties of the base lubricant by decreasing wear and/or friction of sliding and/or rolling surfaces at boundary layers.
FILED Wednesday, February 17, 2016
APPL NO 15/045749
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 125/26 (20130101)
C10M 133/46 (20130101)
C10M 141/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657489 Harper
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) THE BOEING COMPANY (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) David William Harper (Madison, Alabama)
ABSTRACT A structural support having fractal-stiffening and method of fabricating the support is presented where an optimized location of at least three nodes is predetermined prior to fabricating the structural support where a first set of webs is formed on one side of the support and joined to the nodes to form a first pocket region. A second set of webs is formed within the first pocket region forming a second pocket region where the height of the first set of webs extending orthogonally from the side of the support is greater than the second set of webs extending orthogonally from the support.
FILED Monday, June 15, 2015
APPL NO 14/739539
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Aeroplanes; Helicopters
B64C 1/08 (20130101)
B64C 1/12 (20130101)

Structural Elements; Building Materials
E04C 2/08 (20130101)
E04C 2/32 (20130101)
E04C 2/384 (20130101)
E04C 2/427 (20130101)

Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General
E04H 7/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09657858 Ramspacher et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Daniel J. Ramspacher (Washington, District of Columbia);  James A. Richard (Grant, Alabama)
ABSTRACT A non-pyrotechnic, normally-closed, zero-leak valve is a replacement for the pyrovalve used for both in-space and launch vehicle applications. The valve utilizes a magnetostrictive alloy for actuation, rather than pyrotechnic charges. The alloy, such as Terfenol-D, experiences magnetostriction, i.e. a gross elongation, when exposed to a magnetic field. This elongation fractures a parent metal seal, allowing fluid flow through the valve. The required magnetic field is generated by redundant coils that are isolated from the working fluid.
FILED Monday, September 28, 2015
APPL NO 14/868041
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 17/40 (20130101) Original (OR) Class
F16K 31/0679 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/1744 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658251 Cairns et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Goddard Space Flight Center (GSFC)
NASA Shared Services Center (NSSC)
APPLICANT(S) WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia)
ASSIGNEE(S) WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia)
INVENTOR(S) Darran Robert Cairns (Morgantown, West Virginia);  Wade W. Huebsch (Morgantown, West Virginia);  Konstantinos A. Sierros (Morgantown, West Virginia);  Matthew S. Shafran (Austin, Texas)
ABSTRACT Disclosed are various embodiments of methods and systems related to stimulus responsive nanoparticles. In one embodiment includes a stimulus responsive nanoparticle system, the system includes a first electrode, a second electrode, and a plurality of elongated electro-responsive nanoparticles dispersed between the first and second electrodes, the plurality of electro-responsive nanorods configured to respond to an electric field established between the first and second electrodes.
FILED Friday, May 01, 2015
APPL NO 14/701608
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 1/30 (20130101) Original (OR) Class

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660623 Prokop et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Norman Prokop (South Euclid, Ohio);  Michael Krasowski (Chagrin Falls, Ohio)
ABSTRACT A two input time domain correlator may perform analog correlation. In order to achieve high throughput rates with reduced or minimal computational overhead, the input data streams may be hard limited through adaptive thresholding to yield two binary bit streams. Correlation may be achieved through the use of a Hamming distance calculation, where the distance between the two bit streams approximates the time delay that separates them. The resulting Hamming distance approximates the correlation time delay with high accuracy.
FILED Monday, December 02, 2013
APPL NO 14/094006
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 17/15 (20130101)

Pulse Technique
H03K 5/125 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660680 Krasowski et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Michael J. Krasowski (Chagrin Falls, Ohio);  Norman F. Prokop (South Euclid, Ohio);  Lawrence C. Greer, III (Avon, Ohio);  Jennifer M. Nappier (Bay Village, Ohio)
ABSTRACT An apparatus and method are provided for communicating over power lines. The apparatus includes a coupling modem that is situated between a power line and a device. The coupling modem is configured to demodulate a signal received from the power line into a sine signal and a cosine signal. The coupling modem is also configured to modulate a communicated bit stream received from the device into a transmitted signal in order to impose the transmitted signal onto the power line.
FILED Friday, July 31, 2015
APPL NO 14/815189
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Transmission
H04B 1/38 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660908 Murphy
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) Brandon M. Murphy (Huntsville, Alabama)
ABSTRACT A method and apparatus for processing a plurality of data packets. A data packet is received. A determination is made as to whether a portion of the data packet follows a selected digital recorder standard protocol based on a header of the data packet. Raw data in the data packet is converted into human-readable information in response to a determination that the portion of the data packet follows the selected digital recorder standard protocol.
FILED Monday, October 27, 2014
APPL NO 14/524546
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/321 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/0829 (20130101)
H04L 43/0835 (20130101)
H04L 45/74 (20130101) Original (OR) Class
H04L 47/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 09655864 Freyman et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Toby Freyman (Lexington, Massachusetts);  Quynh Pham (Metheun, Massachusetts);  Robert F. Mulligan (Arlington, Massachusetts);  Abby N. Picard (Jamaica Plain, Massachusetts);  Xuri Yan (Brighton, Massachusetts)
ASSIGNEE(S) Arsenal Medical, Inc. (Watertown, Massachusetts)
INVENTOR(S) Toby Freyman (Lexington, Massachusetts);  Quynh Pham (Metheun, Massachusetts);  Robert F. Mulligan (Arlington, Massachusetts);  Abby N. Picard (Jamaica Plain, Massachusetts);  Xuri Yan (Brighton, Massachusetts)
ABSTRACT The present invention relates generally to the field of electrospun fibers. In particular, the present invention relates to core-sheath fibers and related electrospinning methods. The fibers of the invention comprise poorly water soluble drugs and/or proteins.
FILED Friday, March 14, 2014
APPL NO 14/211900
ART UNIT 1789 — Miscellaneous Articles, Stock Material
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/70 (20130101) Original (OR) Class
A61K 31/496 (20130101)
A61K 38/1825 (20130101)
A61K 47/34 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/34 (20130101)
D01D 5/0069 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 1/10 (20130101)

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 15/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658301 Walsworth
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Ronald Walsworth (Newton, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Ronald Walsworth (Newton, Massachusetts)
ABSTRACT Absorption based detection of spin states of spin impurities within a solid-state spin system, such as NV centers in diamond, is implemented by measuring the absorption intensity of an optical signal applied to the spin impurities, i.e. change in intensity of the optical signal after the signal has been transmitted through the solid-state spin system. During optical excitation of the spin impurities, microwave pulses are applied to the sample at a frequency tuned to the ESR frequency. The relative populations of the spin states of the impurities, which provides information regarding variables of interest such as an external magnetic field or a quantum information protocol, is determined from the ratio of the absorption intensity of the optical signal when the microwave pulses are turned on, to the absorption intensity of the optical signal when the microwave pulses turned off.
FILED Tuesday, June 12, 2012
APPL NO 14/125072
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/323 (20130101) Original (OR) Class
G01R 33/1284 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09660721 Polzik et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Kobenhavns Universitet (Copenhagen K, Denmark)
ASSIGNEE(S) Kobenhavns Universitet (Copenhagen K, Denmark);  Danmarks Tekniske Universitet (Kongens Lyngby, Denmark);  National Institute of Standards and Technology, The United States Of America, as Represented by The Secretary Of Commerce (Washington, District of Columbia)
INVENTOR(S) Eugene Simon Polzik (Copenhagen O, Denmark);  Albert Schliesser (Copenhagen K, Denmark);  Silvan Schmid (Copenhagen O, Denmark);  Anders Sondberg Sorensen (Rodovre, Denmark);  Jacob M. Taylor (Washington, District of Columbia);  Koji Usami (Nakahara-ku, Japan);  Tolga Bagci (Ankara, Turkey);  Anders Simonsen (Copenhagen NV, Denmark);  Luis Guillermo Villanueva (Neuchatel, Switzerland);  Emil Zeuthen (Copenhagen N, Denmark);  Juergen Appel (Soberg, Denmark)
ABSTRACT An optical detector for detecting radio frequency (RF) signals, the optical detector comprising a light source and a photodetector, and an electrical circuit comprising a position dependent capacitor and a bias voltage source adapted for providing a bias voltage for biasing the position dependent capacitor, the position dependent capacitor comprising an electrode and a membrane being displaceable in reaction to RF signals incident on the membrane, the membrane being metallized, has a thickness of less than 1 μm and a quality factor, Qm, of at least 20,000, and the distance between the membrane and the electrode being less than 10 μm.
FILED Friday, July 11, 2014
APPL NO 14/328871
ART UNIT 2878 — Optics
CURRENT CPC
Transmission
H04B 10/00 (20130101) Original (OR) Class
H04B 2210/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 09656639 Brooks
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Ernie Brooks (Glynco, Georgia)
ABSTRACT Aspects of the disclosure provide a system and methods for inducing a skid in a vehicle. The system includes a mobile controller corresponding to a vehicle and communicatively coupled to a brake system of the vehicle, and a remote controller in wireless communication with the mobile controller. The remote controller is configured to receive a selection of the mobile controller for issuance of a braking command including a braking setting. In response to receipt of the braking command, the selected mobile controller is configured to operate the brake system of the vehicle to induce a skid in the vehicle according to the braking setting.
FILED Friday, September 30, 2016
APPL NO 15/281703
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Vehicle Brake Control Systems or Parts Thereof; Brake Control Systems or Parts Thereof, in General; Arrangement of Braking Elements on Vehicles in General; Portable Devices for Preventing Unwanted Movement of Vehicles; Vehicle Modifications to Facilitate Cooling of Brakes
B60T 7/18 (20130101) Original (OR) Class
B60T 8/176 (20130101)
B60T 2270/10 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658139 Hering et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) TSI Incorporated (Shoreview, Minnesota)
ASSIGNEE(S) TSI INCORPORATED (Shoreview, Minnesota);  AEROSOL DYNAMICS INC. (Berkley, California)
INVENTOR(S) Susanne V. Hering (Berkeley, California);  Gregory S. Lewis (Berkeley, California);  Arantzazu Eiguren Fernandez (El Cerrito, California);  Frederick Quant (Shoreview, Minnesota);  Kenneth R. Farmer, II (Lake Elmo, Minnesota)
ABSTRACT A system and a method is described herein for the collection of small particles in a concentrated manner, whereby particles are deposited onto a solid surface or collected into a volume of liquid. The collected samples readily interface to any of a number of different elemental, chemical, or biological or other analysis techniques.
FILED Wednesday, August 28, 2013
APPL NO 14/012818
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2202 (20130101) Original (OR) Class
G01N 1/2208 (20130101)
G01N 1/2211 (20130101)
G01N 15/065 (20130101)
G01N 2001/2217 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09659189 Lee et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Wenke Lee (Atlanta, Georgia);  Alexandra Boldyreva (Atlanta, Georgia);  Chung Pak Ho (Atlanta, Georgia);  Billy Lau (Atlanta, Georgia);  Chengyu Song (Atlanta, Georgia)
ABSTRACT The disclosed technology includes techniques for improving data privacy in mobile communications over public cloud services. According to certain implementations, a novel conceptual layer may be interposed between the “application” layer and the “user” layer. In some implementations, the conceptual layer may be at least partially embodied by a transparent window or pane overlaid on top of existing app graphical user interfaces to: (1) intercept plaintext user input before transforming the input and feeding it to an underlying app; and (2) reverse transform output data from the app before displaying the plaintext data to the user. Accordingly, the conceptual layer may serve as a protective layer while preserving the original application workflow and look-and-feel.
FILED Tuesday, October 14, 2014
APPL NO 14/513680
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/6263 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0435 (20130101)

Wireless Communication Networks
H04W 12/00 (20130101)
H04W 12/02 (20130101)
H04W 88/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 09656262 Paliwal et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Saurabh Paliwal (Mountain View, California);  Zhizhong Yin (Timonium, Maryland);  Raymond Cheong (Timonium, Maryland)
ASSIGNEE(S) EUVEDA BIOSCIENCES, INC. (Timonium, Maryland)
INVENTOR(S) Saurabh Paliwal (Mountain View, California);  Zhizhong Yin (Timonium, Maryland);  Raymond Cheong (Timonium, Maryland)
ABSTRACT Microfluidic devices have been developed to perform a range of high-throughput biochemical and cell-based assays over recent years. A design for a microfluidic device has been developed that resembles a microtiter plate, by placing the test chambers (each test chamber contains cells) and top-loading drug inlets (at least one per test chamber) in a grid according to the ANSI/SBS standards, yet offers the miniaturization and fluid handling advantages of microfluidics. This ensures that the device design is compatible with fluid handling and imaging equipment already in use for drug screening. A range of topologies have been determined that allow placement of various elements of this microfluidic network within the grid alignment constraints. A resistance equalization methodology has also been developed to reduce variability across assays run in different chambers of the microfluidic device. Additionally, it offers orders of magnitude miniaturization over multiwell plates, and potentially more reliable fluid handling.
FILED Tuesday, June 10, 2014
APPL NO 14/301319
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502738 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2300/0829 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0874 (20130101)
B01L 2300/0883 (20130101)
B01L 2400/0487 (20130101)
B01L 2400/0655 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0018 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658040 Vasudevan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armament Research, Development and Engineering Center (ARDEC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Srikanth Vasudevan (Shelton, Connecticut);  Paul Suchy (Parma, Ohio);  Matthew C. Birch (Madison, Alabama)
ASSIGNEE(S) Orbital Research Inc. (Cleveland, Ohio)
INVENTOR(S) Srikanth Vasudevan (Shelton, Connecticut);  Paul Suchy (Parma, Ohio);  Matthew C. Birch (Madison, Alabama)
ABSTRACT Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics.
FILED Tuesday, June 21, 2016
APPL NO 15/188093
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Weapon Sights; Aiming
F41G 7/222 (20130101)
F41G 7/2293 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/14 (20130101)
F42B 10/42 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09658314 Parks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Brandon Scott Parks (South Park, Pennsylvania);  Walter J. Keller, III (Bridgeville, Pennsylvania);  Jennting Timothy Hsu (Bethel Park, Pennsylvania)
ASSIGNEE(S) Nokomis, Inc. (Charleroi, Pennsylvania)
INVENTOR(S) Brandon Scott Parks (South Park, Pennsylvania);  Walter J. Keller, III (Bridgeville, Pennsylvania);  Jennting Timothy Hsu (Bethel Park, Pennsylvania)
ABSTRACT A system for identifying a real-world geographic location of an emission source emitting electromagnetic energy includes a platform configured for movement and an apparatus disposed on the platform and configured to collect and process, in a passive manner and during movement of the platform, at least a pair of successive samples of the electromagnetic energy emission and define angular and spatial coordinates of the emission source. The apparatus includes at least a pair of antennas, a receiver coupled to antennas and a processor executing a predetermined logic.
FILED Friday, March 02, 2012
APPL NO 13/410586
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/04 (20130101) Original (OR) Class
G01S 5/0221 (20130101)
G01S 5/0278 (20130101)
G01S 5/0284 (20130101)
G01S 5/0294 (20130101)
G01S 19/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 09655366 Beck et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia);  Wonderful Orchards, LLC (Shafter, California)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia);  Wonderful Orchards, LLC (Shafter, California)
INVENTOR(S) John J Beck (Rocklin, California);  Bradley S Higbee (Shafter, California)
ABSTRACT The present invention relates to formulations of volatile organic compounds having effects on the navel orangeworm moth (NOW). In some embodiments, the blends of volatile organic compounds attract navel orangeworm moths. In other embodiments, the blends disrupt ovipositional activity of the female NOW. The invention also relates to traps baited with any one or more of the disclosed volatile blends, which are effective for controlling NOW.
FILED Friday, September 18, 2015
APPL NO 14/858654
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 27/00 (20130101)
A01N 27/00 (20130101)
A01N 27/00 (20130101)
A01N 27/00 (20130101)
A01N 27/00 (20130101)
A01N 27/00 (20130101)
A01N 27/00 (20130101)
A01N 27/00 (20130101)
A01N 31/02 (20130101)
A01N 31/02 (20130101)
A01N 31/04 (20130101)
A01N 31/04 (20130101)
A01N 31/04 (20130101)
A01N 31/04 (20130101)
A01N 31/04 (20130101)
A01N 31/04 (20130101)
A01N 35/02 (20130101)
A01N 35/02 (20130101)
A01N 35/02 (20130101)
A01N 35/02 (20130101)
A01N 35/02 (20130101)
A01N 35/02 (20130101)
A01N 35/02 (20130101)
A01N 35/04 (20130101)
A01N 35/04 (20130101)
A01N 35/04 (20130101)
A01N 35/04 (20130101)
A01N 35/04 (20130101)
A01N 35/04 (20130101)
A01N 35/04 (20130101)
A01N 37/02 (20130101)
A01N 37/02 (20130101)
A01N 37/02 (20130101)
A01N 37/02 (20130101)
A01N 37/10 (20130101)
A01N 37/10 (20130101)
A01N 37/10 (20130101)
A01N 37/14 (20130101)
A01N 37/40 (20130101)
A01N 37/40 (20130101)
A01N 37/40 (20130101)
A01N 37/40 (20130101)
A01N 43/90 (20130101) Original (OR) Class
A01N 43/90 (20130101)
A01N 43/90 (20130101)
A01N 43/90 (20130101)
A01N 43/90 (20130101)
A01N 49/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 09655535 Narayan et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Topera, Inc. (Menlo Park, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Topera, Inc. (Menlo Park, California);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Sanjiv Narayan (La Jolla, California);  Carey Robert Briggs (La Jolla, California)
ABSTRACT A system and method to target a biological rhythm disorder, such as a heart rhythm disorder include processing cardiac signals via a computing device to determine a shape in a region of tissue defined by a source associated with the biological rhythm disorder that migrates spatially on or within the shape, and identifying at least one portion of the tissue proximate to the shape to enable selective modification of the at least one portion of tissue in order to terminate or alter the heart rhythm disorder.
FILED Thursday, February 18, 2016
APPL NO 15/047266
ART UNIT 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/042 (20130101)
A61B 5/046 (20130101)
A61B 5/0464 (20130101)
A61B 5/04012 (20130101) Original (OR) Class
A61B 5/4029 (20130101)
A61B 5/4064 (20130101)
A61B 5/4839 (20130101)
A61B 18/1492 (20130101)
A61B 2018/00357 (20130101)
A61B 2018/00577 (20130101)
A61B 2018/00839 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 09655523 Hillman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Non-Profit Organization (NPO)
Wallace H Coulter Foundation (WHCF)
APPLICANT(S) Elizabeth Marjorie Clare Hillman (New York, New York);  Sean A. Burgess (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Elizabeth Marjorie Clare Hillman (New York, New York);  Sean A. Burgess (New York, New York)
ABSTRACT Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).
FILED Tuesday, December 29, 2009
APPL NO 12/655325
ART UNIT 3737 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0064 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0071 (20130101)
A61B 5/0073 (20130101)
A61B 5/0075 (20130101)
A61B 5/0088 (20130101)
A61B 5/444 (20130101)
A61B 5/445 (20130101)
A61B 2562/0238 (20130101)
A61B 2562/0242 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101)
G01J 3/457 (20130101)
G01J 3/2889 (20130101)

Optical Elements, Systems, or Apparatus
G02B 23/2476 (20130101)
G02B 26/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 23, 2017.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20170523.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital