FedInvent™ Patents
Patent Details for Tuesday, May 23, 2017
This page was updated on Monday, March 27, 2023 at 05:13 AM GMT
Department of Health and Human Services (HHS)
US 09655512 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | David Huang (Portland, Oregon); Yan Li (Portland, Oregon); Ou Tan (Portland, Oregon); Maolong Tang (Portland, Oregon) |
ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | David Huang (Portland, Oregon); Yan Li (Portland, Oregon); Ou Tan (Portland, Oregon); Maolong Tang (Portland, Oregon) |
ABSTRACT | This invention discloses methods and systems for measuring corneal epithelial thickness and power, stromal thickness, subepitheila corneal power and topography. The systems and methods disclosed herein are non-invasive, non-contact and automated imaging methods which preferably makes use of Fourier-domain optical tomography. Also disclosed herein are scanning patterns and image analysis methods for utilizing and analyzing Fourier-domain optical coherence tomography images to obtain information about conical epithelial and stromal properties as well as parameters useful for evaluating the properties. The methods and systems described herein are useful as eye disease diagnostic tools and eye surgery planning tools. |
FILED | Friday, April 06, 2012 |
APPL NO | 13/441733 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/1005 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/60 (20130101) G06T 2207/10101 (20130101) G06T 2207/30041 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655521 | Iftimia et al. |
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FUNDED BY |
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APPLICANT(S) | Physical Sciences, Inc. (Andover, Massachusetts) |
ASSIGNEE(S) | Physical Sciences, Inc. (Andover, Massachusetts); Memorial Sloan-Kettering Cancer Center (New York, New York) |
INVENTOR(S) | Nicusor V. Iftimia (Chelmsford, Massachusetts); Mircea Mujat (Acton, Massachusetts); R. Daniel Ferguson (Melrose, Massachusetts); Ankit H. Patel (Methuen, Massachusetts); Milind Rajadhyaksha (New York, New York) |
ABSTRACT | A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path. |
FILED | Thursday, January 31, 2013 |
APPL NO | 13/755741 |
ART UNIT | 3737 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/0068 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655522 | Li et al. |
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APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
INVENTOR(S) | Debiao Li (South Pasadena, California); Behzad Sharif (Los Angeles, California); Daniel S. Berman (Los Angeles, California); Jianing Pang (Beverly Hills, California) |
ABSTRACT | The present invention teaches systems and methods for a simple cardiac MRI approach that (1) continuously acquires data; (2) covers the entire heart with high isotropic resolution within a few minutes; and (3) requires no physiological gating and minimal user intervention. Applications of the inventive systems and methods include, but are in no way limited to cardiac cine, myocardial perfusion, coronary MRA, delayed enhancement imaging, myocardial T1-weighted imaging for fibrosis imaging, and myocardial T2-weighted imaging for edema imaging. |
FILED | Thursday, October 08, 2015 |
APPL NO | 14/878937 |
ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) Original (OR) Class A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4826 (20130101) G01R 33/4838 (20130101) G01R 33/5602 (20130101) G01R 33/5608 (20130101) G01R 33/5611 (20130101) G01R 33/5635 (20130101) G01R 33/56325 (20130101) G01R 33/56366 (20130101) G01R 33/56509 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) Image Data Processing or Generation, in General G06T 7/337 (20170101) G06T 2207/10016 (20130101) G06T 2207/10088 (20130101) G06T 2207/30048 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655523 | Hillman et al. |
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APPLICANT(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Sean A. Burgess (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Sean A. Burgess (New York, New York) |
ABSTRACT | Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM). |
FILED | Tuesday, December 29, 2009 |
APPL NO | 12/655325 |
ART UNIT | 3737 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0064 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/0071 (20130101) A61B 5/0073 (20130101) A61B 5/0075 (20130101) A61B 5/0088 (20130101) A61B 5/444 (20130101) A61B 5/445 (20130101) A61B 2562/0238 (20130101) A61B 2562/0242 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/457 (20130101) G01J 3/2889 (20130101) Optical Elements, Systems, or Apparatus G02B 23/2476 (20130101) G02B 26/101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655527 | Wang et al. |
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APPLICANT(S) | Washington University (St. Louis, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Lihong Wang (Creve Coeur, Missouri); Zijian Guo (St. Louis, Missouri) |
ABSTRACT | Accurately quantifying optical absorption coefficient using acoustic spectra of photoacoustic signals. Optical absorption is closely associated with many physiological parameters, such as the concentration and oxygen saturation of hemoglobin, and it can be used to quantify the concentrations of non-fluorescent molecules. A sample is illuminated by, for example, a pulsed laser and following the absorption of optical energy, a photoacoustic pressure is generated via thermo-elastic expansion. The acoustic waves then propagate and are detected by a transducer. The optical absorption coefficient of the sample is quantified from spectra of the measured photoacoustic signals. Factors, such as system bandwidth and acoustic attenuation, may affect the quantification but are canceled by dividing the acoustic spectra measured at multiple optical wavelengths. |
FILED | Thursday, June 11, 2015 |
APPL NO | 14/736768 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0095 (20130101) Original (OR) Class A61B 5/417 (20130101) A61B 5/7257 (20130101) A61B 5/14542 (20130101) A61B 5/14546 (20130101) A61B 8/13 (20130101) A61B 8/5215 (20130101) A61B 2576/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655535 | Narayan et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California) |
ABSTRACT | A system and method to target a biological rhythm disorder, such as a heart rhythm disorder include processing cardiac signals via a computing device to determine a shape in a region of tissue defined by a source associated with the biological rhythm disorder that migrates spatially on or within the shape, and identifying at least one portion of the tissue proximate to the shape to enable selective modification of the at least one portion of tissue in order to terminate or alter the heart rhythm disorder. |
FILED | Thursday, February 18, 2016 |
APPL NO | 15/047266 |
ART UNIT | 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/042 (20130101) A61B 5/046 (20130101) A61B 5/0464 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/4029 (20130101) A61B 5/4064 (20130101) A61B 5/4839 (20130101) A61B 18/1492 (20130101) A61B 2018/00357 (20130101) A61B 2018/00577 (20130101) A61B 2018/00839 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655545 | Ji et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
INVENTOR(S) | Songbai Ji (Lebanon, New Hampshire); David W. Roberts (Lyme, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire) |
ABSTRACT | An apparatus and method for measuring mechanical properties of tissue has a stereo optical surgical microscope with at least one objective lens and at least two digital cameras such that paired images obtained from the digital cameras form stereo pairs, and a digital image processing system adapted to determine surface topography of tissue from the stereo pairs of images and a resulting surface displacement map as a result from indentation. The apparatus has an one indenter; and mechanical modeling routines stored in memory of the image processing system, the mechanical modeling routines capable of constructing computer models of mechanical properties of tissue, and fitting parameters of the computer model to observed surface displacement maps generated by coregistering surface topography of tissue with and without the indenter positioned on the tissue. In an embodiment, fitted parameters of the computer model are displayed and used to adjust a surgical plan. An apparatus and method for measuring mechanical properties of tissue has a stereo optical surgical microscope with at least one objective lens and at least two digital cameras such that paired images obtained from the digital cameras form stereo pairs, and a digital image processing system adapted to determine surface topography of tissue from the stereo pairs of images and a resulting surface displacement map as a result from indentation. The apparatus has an one indenter; and mechanical modeling routines stored in memory of the image processing system, the mechanical modeling routines capable of constructing computer models of mechanical properties of tissue, and fitting parameters of the computer model to observed surface displacement maps generated by coregistering surface topography of tissue with and without the indenter positioned on the tissue. In an embodiment, fitted parameters of the computer model are displayed and used to adjust a surgical plan. |
FILED | Monday, September 17, 2012 |
APPL NO | 14/345029 |
ART UNIT | 3768 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0053 (20130101) A61B 5/0077 (20130101) A61B 5/1079 (20130101) Original (OR) Class A61B 90/20 (20160201) A61B 2090/364 (20160201) A61B 2090/371 (20160201) Optical Elements, Systems, or Apparatus G02B 21/0012 (20130101) G02B 21/367 (20130101) Image Data Processing or Generation, in General G06T 7/344 (20170101) G06T 2200/04 (20130101) G06T 2207/10012 (20130101) G06T 2207/10056 (20130101) G06T 2207/30016 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655595 | Glossop et al. |
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APPLICANT(S) | Arcitrax Inc. (Toronto, Canada); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | Arcitrax Inc. (Ontario, Canada); The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Neil Glossop (Toronto, Canada); Bradford Wood (North Bethesda, Maryland) |
ABSTRACT | Methods, systems, and devices for assisting or performing an image-guided prostate procedure are disclosed. A needle assembly includes a needle guide, a needle device, a position sensor and additional features. The position sensor allows for the tracking of the needle assembly. A method for performing image-guided prostate procedures includes pre-operative procedures and intra-operative procedures. The pre-operative procedures include imaging studies to model the prostate and identify targets. The pre-operative procedures models are used during a prostate procedure to track the target and the devices used for the procedure. A system for performing image-guided procedures includes the needle assembly and other components. |
FILED | Friday, June 14, 2013 |
APPL NO | 13/918413 |
ART UNIT | 3768 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/066 (20130101) A61B 5/4887 (20130101) A61B 10/0241 (20130101) Original (OR) Class A61B 10/0275 (20130101) A61B 17/3403 (20130101) A61B 34/20 (20160201) A61B 90/37 (20160201) A61B 2017/00092 (20130101) A61B 2017/00274 (20130101) A61B 2017/3413 (20130101) A61B 2034/2051 (20160201) A61B 2090/365 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655679 | Desai et al. |
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APPLICANT(S) | UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION (College Park, Maryland) |
ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
INVENTOR(S) | Jaydev P. Desai (Bethesda, Maryland); Elif Ayvali (College Park, Maryland) |
ABSTRACT | A steerable probe having high-power-density actuators positioned at joints along the length of the probe. The actuators are moveable about and between a straight position and a curved position in response to selective actuation. |
FILED | Wednesday, May 01, 2013 |
APPL NO | 13/875204 |
ART UNIT | 3779 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3417 (20130101) A61B 17/3421 (20130101) A61B 19/201 (20130101) Original (OR) Class A61B 90/11 (20160201) A61B 90/39 (20160201) A61B 2017/003 (20130101) A61B 2017/00867 (20130101) A61B 2034/2055 (20160201) A61B 2090/3735 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655720 | Bluestein et al. |
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APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York); The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
INVENTOR(S) | Danny Bluestein (Melville, New York); Thomas E. Claiborne (Bayport, New York); Marvin J. Slepian (Tucson, Arizona) |
ABSTRACT | A polymeric valve which may include a heart valve, and also may include a trileaflet heart valve includes a stent having a base and a plurality of outwardly extending posts from the base and equidistant from each other. A plurality of leaflets each connected to a corresponding one of the posts at one end, and each of the leaflets connected to the base. Each of the leaflets having an operative end opposite the end connected to the post, and the operative ends of the leaflets being biased in a closed position such that the operative ends abut each other. The operative ends are configured to rhythmically open and close in relation to each other, and the leaflets include multiple cross sectional thicknesses at different portions of the leaflets. |
FILED | Friday, October 12, 2012 |
APPL NO | 14/351455 |
ART UNIT | 3738 — Optics |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2412 (20130101) A61F 2/2415 (20130101) Original (OR) Class A61F 2/2418 (20130101) A61F 2250/0036 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655774 | Tai et al. |
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APPLICANT(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
INVENTOR(S) | Yu-Chong Tai (Pasadena, California); Nicholas Scianmarello (Pasadena, California); Dongyang Kang (Pasadena, California); Jungwook Park (Pasadena, California); Mark S. Humayun (Glendale, California); Karthik Murali (Los Angeles, California); Amir H. Kashani (Pasadena, California); Hossein Nazari Khanamiri (South Pasadena, California) |
ABSTRACT | A medical device having a permeable bag connected by a non-permeable cannula to a discharge sac is described along with a manufacturing process and surgical implantation method. The permeable portions of the device have pores that are sized to be permeable to a predetermined class of small molecules, such as oxygen, nitrous oxide, or other therapeutic agents. Once absorbed inside the device, the small molecules are then passively transported, by a concentration gradient of the small molecules, to the discharge sac to be disbursed. A metal tube or other strip can be included in the cannula to assist a surgeon in orienting the device within the body. |
FILED | Friday, June 19, 2015 |
APPL NO | 14/744439 |
ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Original (OR) Class A61F 2240/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/10 (20130101) B29C 41/36 (20130101) B29C 65/02 (20130101) B29C 66/54 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/919 (20130101) B29C 66/949 (20130101) B29C 66/1142 (20130101) B29C 66/3242 (20130101) B29C 66/73754 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/005 (20130101) B29K 2083/005 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7548 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655815 | Xiang et al. |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Rong Xiang (San Diego, California); He Zhou (San Diego, California); Ralph A Reisfeld (La Jolla, California) |
ABSTRACT | A DNA vaccine suitable for eliciting an immune response against cancer cells comprises a DNA construct operably encoding a cancer-associated Inhibitor of Apoptosis-family protein and an immunoactive gene product, such as a cytokine or a ligand for a natural killer cell surface receptor, in a pharmaceutically acceptable carrier. A preferred cytokine is CCL21. Preferred ligands for a natural killer cell surface receptor include human MICA, human MICB, human ULBP1, human ULBP2, and human ULBP3. The cancer-associated Inhibitor of Apoptosis (IAP)-family protein is preferably a survivin protein or livin protein. Method of inhibiting tumor growth by administering the vaccine of the invention to a mammal is also described. |
FILED | Monday, May 05, 2014 |
APPL NO | 14/269998 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/05 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 6/00 (20130101) A61K 39/0011 (20130101) A61K 2039/53 (20130101) A61K 2039/523 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655839 | Fagerberg et al. |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
INVENTOR(S) | Marcelle Matos Nascimento Fagerberg (Gainesville, Florida); Robert A. Burne (Gainesville, Florida) |
ABSTRACT | The present disclosure provides probiotic arginolytic oral compositions, methods of making probiotic arginolytic oral compositions, and methods of using probiotic arginolytic oral compositions to increase arginolytic activity in the oral cavity and/or to treat and/or prevent caries. |
FILED | Wednesday, February 12, 2014 |
APPL NO | 14/767181 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/99 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 31/7004 (20130101) A61K 35/741 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 11/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/315 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655882 | Zack et al. |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Donald J. Zack (Baltimore, Maryland); Zhiyong Yang (Baltimore, Maryland); Cynthia Berlinicke (Baltimore, Maryland); Harry Quigley (Baltimore, Maryland) |
ABSTRACT | Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed. |
FILED | Thursday, February 19, 2015 |
APPL NO | 14/626524 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/404 (20130101) Original (OR) Class A61K 31/404 (20130101) A61K 31/496 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655914 | Cheng et al. |
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APPLICANT(S) | University of South Florida (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Jin Q. Cheng (Tampa, Florida); Said M. Sebti (Tampa, Florida) |
ABSTRACT | This application relates to combination therapies including triciribine compounds and epidermal growth factor receptor inhibitor compounds, particularly erlotinib-like compounds and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/998352 |
ART UNIT | 1673 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/517 (20130101) A61K 31/5377 (20130101) A61K 31/7064 (20130101) Original (OR) Class A61K 31/7076 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655950 | Geskin et al. |
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APPLICANT(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Larisa Geskin (Pittsburgh, Pennsylvania); Oleg E. Akilov (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to methods and materials for more effectively treating patients with interferon. It is based on the discovery that clinical response to interferon (IFN) therapy is mediated in part by inhibition of activation of MDSC and such inhibition can be observed after a test dose of interferon; a significant decrease of reactive oxygen species (ROS) production by MDSC (as a measure of their activation) after IFN therapy is predictive of overall response to immunotherapy in cancer patients. |
FILED | Thursday, November 06, 2014 |
APPL NO | 14/535198 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/212 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) G01N 33/5011 (20130101) G01N 33/57407 (20130101) G01N 2333/90 (20130101) G01N 2333/978 (20130101) G01N 2333/4706 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655952 | Lanza et al. |
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APPLICANT(S) | Washington University (St. Louis, Missouri) |
ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
INVENTOR(S) | Gregory M. Lanza (St. Louis, Missouri); Dipanjan Pan (St. Louis, Missouri); Allan Doctor (St. Louis, Missouri); Philip C. Spinella (St. Louis, Missouri) |
ABSTRACT | The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood. |
FILED | Tuesday, August 09, 2016 |
APPL NO | 15/232298 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0026 (20130101) A61K 9/51 (20130101) A61K 9/107 (20130101) A61K 38/42 (20130101) Original (OR) Class A61K 38/42 (20130101) A61K 38/063 (20130101) A61K 38/063 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655953 | Muro Galindo et al. |
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FUNDED BY |
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APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Silvia Muro Galindo (Silver Spring, Maryland); Vladimir R. Muzykantov (Bryn Athyn, Pennsylvania); Edward Howard Schuchman (Haworth, New Jersey) |
ABSTRACT | The present invention relates to compositions and methods for delivering lysosomal proteins. The compositions and methods described herein permit the targeted delivery of exogenous lysosomal proteins to cell surface proteins that allow their internalization via non-clathrin pathways. The present invention further relates to the use of the compositions and methods for enzyme replacement therapy of lysosomal storage diseases. Nucleic acids, recombinant cells and kits useful for making and using the compositions of the invention are also provided. |
FILED | Thursday, October 16, 2014 |
APPL NO | 14/516231 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 47/48561 (20130101) Peptides C07K 16/2821 (20130101) C07K 2317/77 (20130101) C07K 2319/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/04012 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) Y10T 428/2991 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655963 | Suzuki et al. |
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FUNDED BY |
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APPLICANT(S) | THE UAB RESEARCH FOUNDATION (Birmingham, Alabama); US ARMY WALTER REED ARMY MEDICAL CENTER, CHIEF, OFFICE OF RESEARCH, MARKETING and POLICY DEV (Washington, District of Columbia); JUNTENDO UNIVERSITY SCHOOL OF MEDICINE, DIVISION OF NEPHROLOGY, DEPARTMENT OF INTERNAL MEDICINE (Tokyo, Japan); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee) |
ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); US Army Walter Reed Army Medical Center, Chief, Office Of Research, Marketing and Policy Dev Walter Reed Army Institute of Research (Washington, District of Columbia); Juntendo University School of Medicine, Division of Nephrology, Department of Internal Medicine (Tokyo, Japan); University of Tennessee Research Foundation (Memphis, Tennessee) |
INVENTOR(S) | Hitoshi Suzuki (Hoover, Alabama); Run Fan (Omaha, Nebraska); Bruce A. Julian (Birmingham, Alabama); Jan Novak (Pelham, Alabama); Zina Moldoveanu (Birmingham, Alabama); Zhixin Zhang (Omaha, Nebraska); Milan Tomana (Birmingham, Alabama); Jiri Mestecky (Birmingham, Alabama); Robert J. Wyatt (Memphis, Tennessee); Yasuhiko Tomino (Tokyo, Japan); Yusuke Suzuki (Tokyo, Japan); Stephen Olson (Rockville, Maryland); Matthew B. Renfrow (Birmingham, Alabama) |
ABSTRACT | Provided are methods of diagnosing IgA nephropathy in a subject. Optionally, the methods comprise isolating an IgG from the subject and determining whether the IgG binds to a galactose-deficient IgA1. Optionally, the methods comprise providing a biological sample from the subject and detecting in the sample a mutation in a IGH gene, wherein the mutation is in a nucleotide sequence encoding a complementarity determining region 3 (CDR3) of a IGH variable region. Optionally, the methods comprise determining a level of IgG specific for a galactose-deficient IgA1 in the subject. Also provided are methods of treating or reducing the risk of developing IgA nephropathy in a subject. |
FILED | Friday, June 27, 2014 |
APPL NO | 14/318082 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39541 (20130101) Original (OR) Class Peptides C07K 16/4283 (20130101) C07K 2317/41 (20130101) C07K 2317/55 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/6893 (20130101) G01N 2800/347 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655973 | Mann |
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FUNDED BY |
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APPLICANT(S) | Vascular Biosciences (San Diego, California) |
ASSIGNEE(S) | Vascular Biosciences (San Diego, California) |
INVENTOR(S) | David M. Mann (San Diego, California) |
ABSTRACT | Disclosed are compositions and methods useful for oral delivery of targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. The disclosed targeting is useful for oral delivery of therapeutic and detectable agents to diseased tissue in an animal. |
FILED | Monday, March 11, 2013 |
APPL NO | 14/383818 |
ART UNIT | 1676 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 47/42 (20130101) Original (OR) Class A61K 47/48238 (20130101) Peptides C07K 7/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655993 | Kaplan et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Fiorenzo Omenetto (Wakefield, Massachusetts); Jeffrey K. Marchant (Littleton, Massachusetts); Noorjahan Panjwani (Medford, Massachusetts); Brian Lawrence (Minneapolis, Minnesota) |
ABSTRACT | This invention relates to a lamellae tissue layer, comprising a grooved silk fibroin substrate comprising tissue-specific cells. The silk fibroin substrates provides an excellent means of controlling and culturing cell and extracellular matrix development. A multitude of lamellae tissue layers can be used to create a tissue-engineered organ, such as a tissue-engineered cornea. The tissue-engineered organ is non-immunogenic and biocompatible. |
FILED | Tuesday, July 07, 2015 |
APPL NO | 14/793464 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/56 (20130101) A61L 27/225 (20130101) A61L 27/227 (20130101) A61L 27/3604 (20130101) Original (OR) Class A61L 27/3804 (20130101) A61L 27/3839 (20130101) A61L 27/3891 (20130101) A61L 2300/412 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0621 (20130101) C12N 2533/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656059 | Greenberg et al. |
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FUNDED BY |
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APPLICANT(S) | Second Sight Medical Products, Inc. (San Fernando, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Robert J Greenberg (Los Angeles, California); David D Zhou (Saugus, California); Jordan Matthew Neysmith (Pasadena, California); Kelly H McClure (Simi Valley, California); Jianing Wei (Valencia, California); Neil H Talbot (La Crecenta, California); James S Little (Newhall, California) |
ABSTRACT | A cochlear stimulation device comprising an electrode array designed to provide enhanced charge injection capacity necessary for neural stimulation. The electrode array comprises electrodes with high surface area or a fractal geometry and correspondingly high electrode capacitance and low electrical impedance. The resultant electrodes have a robust surface and sufficient mechanical strength to withstand physical stress vital for long term stability. The device further comprises wire traces having a multilayer structure which provides a reduced width for the conducting part of the electrode array. The cochlear prosthesis is attached by a grommet to the cochleostomy that is made from a single piece of biocompatible polymer. The device, designed to achieve optimum neural stimulation by appropriate electrode design, is a significant improvement over commercially available hand-built devices. |
FILED | Friday, October 17, 2014 |
APPL NO | 14/517638 |
ART UNIT | 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0472 (20130101) A61N 1/0541 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656066 | Nuccitelli et al. |
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FUNDED BY |
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APPLICANT(S) | Pulse Biosciences, Inc. (Burlingame, California) |
ASSIGNEE(S) | PULSE BIOSCIENCES, INC. (Burlingame, California) |
INVENTOR(S) | Richard Lee Nuccitelli (Millbrae, California); Pamela Nuccitelli (Millbrae, California); Joanne Lum (San Francisco, California); Kaying Lui (Millbrae, California); Brian Athos (San Francisco, California); Mark Kreis (San Francisco, California); Zachary Mallon (San Francisco, California); Jon Berridge (Oakland, California) |
ABSTRACT | Nanosecond pulsed electric field (nsPEF) treatments of a tumor are adjusted based on size and type of a tumor to stimulate an immune response against the tumor and other tumors in a subject. Calreticulin expression on tumor cells can be detected to confirm treatment. An immune response biomarker can be measured, and further nsPEF treatments can be performed if needed to stimulate or further stimulate the immune response. Cancers that have metastasized may be treated by directly treating a tumor that is most accessible. The treatment can be combined with CD47-blocking antibodies, doxorubicin, CTLA-4-blocking antibodies, and/or PD-1-blocking antibodies. Electrical characteristics of nsPEF treatments can be based on the size, type, and/or strength of tumors and/or a quantity of tumors in the subject. |
FILED | Wednesday, July 22, 2015 |
APPL NO | 14/805828 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/1477 (20130101) A61B 2018/0016 (20130101) A61B 2018/00613 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/32 (20130101) A61N 1/36 (20130101) Original (OR) Class A61N 1/40 (20130101) A61N 1/327 (20130101) A61N 1/0412 (20130101) A61N 1/0424 (20130101) A61N 1/37229 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) C12N 15/87 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656069 | Danilov et al. |
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FUNDED BY |
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APPLICANT(S) | Yuri P. Danilov (Middleton, Wisconsin); Mitchell E. Tyler (Madison, Wisconsin); Kurt A. Kaczmarek (Madison, Wisconsin) |
ASSIGNEE(S) | |
INVENTOR(S) | Yuri P. Danilov (Middleton, Wisconsin); Mitchell E. Tyler (Madison, Wisconsin); Kurt A. Kaczmarek (Madison, Wisconsin) |
ABSTRACT | A method to provide non-invasive neurostimulation to enhance a subject's proficiency in an exercise includes: (a) engaging a subject in an exercise, the subject having no cognitive, physical or emotional impairment with respect to the exercise; (b) providing stimulation of at least one of the subject's trigeminal nerve, facial nerve or hypoglossal nerve by delivering electrical pulses generated by a signal generator to the subject's skin via at least one electrode in contact with the subject's skin, the delivery of electrical pulses being (i) contemporaneously with and independent of the subject's engagement in the exercise, and (ii) independent of the subject's surrounding environment; and (c) repeating steps (a) and (b) on a periodic basis. |
FILED | Monday, July 11, 2016 |
APPL NO | 15/207029 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0456 (20130101) A61N 1/0476 (20130101) A61N 1/0548 (20130101) A61N 1/36014 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656078 | Danilov et al. |
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FUNDED BY |
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APPLICANT(S) | Yuri P. Danilov (Middleton, Wisconsin); Mitchell E. Tyler (Madison, Wisconsin); Kurt A. Kaczmarek (Madison, Wisconsin) |
ASSIGNEE(S) | |
INVENTOR(S) | Yuri P. Danilov (Middleton, Wisconsin); Mitchell E. Tyler (Madison, Wisconsin); Kurt A. Kaczmarek (Madison, Wisconsin) |
ABSTRACT | In a patient suffering from neural impairment, stimulation is provided to sensory surfaces of the face and/or neck, or more generally to areas of the body that stimulate the trigeminal nerve, while performing an activity intended to stimulate a brain function to be rehabilitated. The simulation may then be continued after the performance of the activity has ceased. It has been found that the patient's performance of the activity is then improved after stimulation has ceased. Moreover, it tends to improve to a greater extent, and/or for a longer time, when the post-activity stimulation is applied, as compared to when post activity stimulation is not applied. |
FILED | Friday, February 06, 2015 |
APPL NO | 14/615766 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/361 (20130101) A61N 1/0548 (20130101) A61N 1/36067 (20130101) A61N 1/36078 (20130101) A61N 1/36092 (20130101) A61N 1/36096 (20130101) A61N 1/36103 (20130101) Original (OR) Class Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656293 | Kuan et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Aaron T. Kuan (Cambridge, Massachusetts); Jene A. Golovchenko (Lexington, Massachusetts) |
ABSTRACT | In a method for forming nanopores, two opposing surfaces of a membrane are exposed to an electrically conducting liquid environment. A nanopore nucleation voltage pulse, having a first nucleation pulse amplitude and duration, is applied between the two membrane surfaces, through the liquid environment. After applying the nanopore nucleation voltage pulse, the electrical conductance of the membrane is measured and compared to a first prespecified electrical conductance. Then at least one additional nanopore nucleation voltage pulse is applied between the two membrane surfaces, through the liquid environment, if the measured electrical conductance is no greater than the first prespecified electrical conductance. At least one nanopore diameter tuning voltage pulse, having a tuning pulse voltage amplitude and duration, is applied between the two membrane surfaces, through the liquid environment, if the measured electrical conductance is greater than the first prespecified electrical conductance and no greater than a second prespecified electrical conductance. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/213243 |
ART UNIT | 1754 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Separation B01D 67/0034 (20130101) B01D 67/0062 (20130101) B01D 67/0065 (20130101) B01D 69/02 (20130101) B01D 2323/35 (20130101) B01D 2325/02 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/34 (20130101) Original (OR) Class Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/00 (20130101) C25F 3/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656953 | Sebti et al. |
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FUNDED BY |
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APPLICANT(S) | University of South Florida (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Said M. Sebti (Tampa, Florida); Srikumar Chellappan (Tampa, Florida); Nicholas James Lawrence (Tampa, Florida) |
ABSTRACT | The disclosed modulators of Rb:Raf-1 interactions are potent, selective disruptors of Rb:Raf-1 binding, with IC50 values ranging from 80 nM to 500 nM. Further, these compounds are surprisingly effective in inhibiting a wide variety of cancer cells, including osteosarcoma, epithelial lung carcinoma, non-small cell lung carcinoma, three different pancreatic cancer cell lines, two different glioblastoma cell lines, metastatic breast cancer, melanoma, and prostate cancer. Moreover, the disclosed compounds effectively disrupt angiogenesis and significantly inhibited tumors in nude mice derived from human epithelial lung carcinoma tumors. Accordingly, the disclosed compounds, pharmaceutical compositions comprising the compounds, methods of inhibiting cell proliferation, methods of treating subjects with cancer, and methods of preparing the disclosed compounds are provided. |
FILED | Monday, February 03, 2014 |
APPL NO | 14/171273 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 279/06 (20130101) C07C 323/45 (20130101) Original (OR) Class C07C 335/32 (20130101) Heterocyclic Compounds C07D 213/53 (20130101) C07D 215/12 (20130101) C07D 233/30 (20130101) C07D 233/84 (20130101) C07D 235/28 (20130101) C07D 249/12 (20130101) C07D 249/14 (20130101) C07D 277/40 (20130101) C07D 277/42 (20130101) C07D 317/56 (20130101) C07D 317/58 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656981 | Spigelman et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Igor Spigelman (Los Angeles, California); Herbert H. Seltzman (Raleigh, North Carolina); Craig Shiner (Durham, North Carolina) |
ABSTRACT | Peripherally acting cannabinoid agonist compounds, pharmaceutical compositions, and methods of using them are presented. |
FILED | Friday, July 19, 2013 |
APPL NO | 14/416026 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 13/465 (20130101) C07C 39/04 (20130101) C07C 43/215 (20130101) C07C 49/788 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/12 (20130101) C07D 215/12 (20130101) C07D 215/14 (20130101) C07D 217/02 (20130101) C07D 295/03 (20130101) C07D 295/037 (20130101) C07D 295/073 (20130101) C07D 295/096 (20130101) C07D 307/52 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656994 | Bannister et al. |
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FUNDED BY |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Thomas D. Bannister (Palm Beach Gardens, Florida); Claes R. Wahlestedt (Palm Beach, Florida); Yen Ting Chen (Palm Beach Gardens, Florida); Shaun P. Brothers (Port St. Lucie, Florida); Hasib Salah-Uddin (Jupiter, Florida); Xiaohong Pan (Palm Beach Gardens, Florida) |
ABSTRACT | The invention provides modulators of the nociceptin receptor (NOP), including both agonists and antagonists. A compound of the invention can be a selective modulator of NOP with respect to the μ- and κ-opioid receptors (MOP and KOP), thus providing a therapeutic method for the treatment of conditions wherein selective NOP modulation is medically indicated and MOP or KOP modulation may be less desirable. A compound of the invention can be a NOP full agonist, partial agonist, inverse agonist, positive or negative allosteric modulator, or a functionally biased agonist. A compound of the invention can be used for the treatment of an anxiety state, post-traumatic stress disorder, addictive disorders (including overuse of alcohol, tobacco, and drugs of abuse such as cocaine, amphetamines, and opitates), misregulated food intake and/or energy expenditure, cough, sleep disorders, migraine, pain, depression, or neurodegenerative disorders such as Parkinsons disease or Alzheimers disease. |
FILED | Friday, March 21, 2014 |
APPL NO | 14/779191 |
ART UNIT | 1672 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 405/14 (20130101) C07D 417/14 (20130101) C07D 451/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657013 | Cuconati et al. |
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FUNDED BY |
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APPLICANT(S) | Baruch S. Blumberg Institute (Doylestown, Pennsylvania); Drexel University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Baruch S. Blumberg Institute (Doylestown, Pennsylvania); Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Andrea Cuconati (Oreland, Pennsylvania); Haitao Guo (Lansdale, Pennsylvania); Timothy M. Block (Doylestown, Pennsylvania); Ju-Tao Guo (Lansdale, Pennsylvania); Xiaodong Xu (Doylestown, Pennsylvania); Huagang Lu (Plainsboro, New Jersey); Dawei Cai (Doylestown, Pennsylvania) |
ABSTRACT | Pharmaceutical compositions of the invention comprise covalently closed circular DNA formation inhibitors having a disease-modifying action in the treatment of diseases associated with the formation of covalently closed circular DNA that include hepatitis B infection, and any disease involving formation of covalently closed circular DNA. |
FILED | Thursday, February 28, 2013 |
APPL NO | 14/382074 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/445 (20130101) A61K 31/505 (20130101) A61K 31/4409 (20130101) A61K 31/4465 (20130101) Acyclic or Carbocyclic Compounds C07C 311/21 (20130101) C07C 317/32 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 211/26 (20130101) C07D 211/34 (20130101) C07D 211/60 (20130101) C07D 213/40 (20130101) C07D 213/56 (20130101) C07D 213/76 (20130101) C07D 235/08 (20130101) C07D 239/26 (20130101) C07D 263/56 (20130101) C07D 277/64 (20130101) C07D 295/135 (20130101) C07D 295/155 (20130101) C07D 401/12 (20130101) C07D 471/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657046 | Umetsu et al. |
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FUNDED BY |
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APPLICANT(S) | Dale T. Umetsu (Newton, Massachusetts); Rosemarie H. De Kruyff (Newton, Massachusetts); Ya-Jen Chang (Brookline, Massachusetts); Petr Illarionov (Birmingham, United Kingdom) |
ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); University of Birmingham (Birmingham, United Kingdom) |
INVENTOR(S) | Dale T. Umetsu (Newton, Massachusetts); Rosemarie H. De Kruyff (Newton, Massachusetts); Ya-Jen Chang (Brookline, Massachusetts); Petr Illarionov (Birmingham, United Kingdom) |
ABSTRACT | The inventors demonstrate that treatment of young, suckling mice with a glycolipid derived from Helicobacter pylori activates NKT cells in a CD1d-restricted fashion, and is protective against AHR in a model of allergen-induced asthma. The inventors further found that this protective effect can be transferred by NKT cells exposed to the glycolipid, and is associated with the expansion of a suppressive double-negative NKT cells and Foxp3+ TReg cells. The inventors also demonstrate herein that pre-treatment of adult mice with a glycolipid derived from Helicobacter pylori partially suppresses airway hyperreactivity and inhibits BAL inflammation in an ozone-exposure model. Accordingly, provided herein are compositions and methods for the treatment and prevention of inflammatory diseases, such as asthma or autoimmune diseases, in a subject in need thereof. |
FILED | Tuesday, May 24, 2011 |
APPL NO | 13/699436 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/56 (20130101) A61K 31/70 (20130101) A61K 31/704 (20130101) A61K 35/15 (20130101) A61K 35/15 (20130101) A61K 35/17 (20130101) A61K 35/17 (20130101) A61K 2039/572 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657053 | Thacher et al. |
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FUNDED BY |
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APPLICANT(S) | ORPHAGEN PHARMACEUTICALS (San Diego, California) |
ASSIGNEE(S) | ORPHAGEN PHARMACEUTICALS (San Diego, California) |
INVENTOR(S) | Scott Thacher (San Diego, California); Xiaolin Li (San Diego, California); Robert Babine (Carlsbad, California); Bruno Tse (San Francisco, California) |
ABSTRACT | Methods for modulating (inhibiting or stimulating) retinoid-related orphan receptor γ (RORγ) activity. This modulation has numerous effects, including inhibition of TH-17 cell function and/or TH-17 cell activity, and inhibition of re-stimulation of TH-17 cells, which are beneficial to treatment of inflammation and autoimmune disorders. Stimulation of RORγ results in stimulation of TH-17 cell function and/or activity which is beneficial for immune-enhancing compositions (e.g., vaccines). |
FILED | Wednesday, February 13, 2013 |
APPL NO | 13/766076 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) Acyclic or Carbocyclic Compounds C07C 311/21 (20130101) Heterocyclic Compounds C07D 249/12 (20130101) C07D 401/14 (20130101) C07D 493/10 (20130101) Steroids C07J 9/00 (20130101) C07J 9/005 (20130101) Original (OR) Class C07J 21/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657060 | Carroll et al. |
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FUNDED BY |
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APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Michael C. Carroll (Wellesley, Massachusetts); Francis D. Moore (Medfield, Massachusetts); Herbert B. Hechtman (Chestnut Hill, Massachusetts) |
ABSTRACT | The invention provides natural IgM antibody inhibitors that may be used to treat various inflammatory diseases or disorders. |
FILED | Tuesday, April 09, 2013 |
APPL NO | 13/859054 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/00 (20130101) A61K 2039/57 (20130101) A61K 2039/505 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 16/00 (20130101) C07K 16/18 (20130101) C07K 16/28 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657066 | Pastan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Ira H. Pastan (Potomac, Maryland); Masanori Onda (Rockville, Maryland); Wenhai Liu (Plantsville, Connecticut) |
ABSTRACT | The invention provides a Pseudomonas exotoxin A (PE) comprising an amino acid sequence having a substitution of one or more of amino acid residues E420, D463, Y481, L516, R563, D581, D589, and K606, wherein the amino acid residues are defined by reference to SEQ ID NO: 1. The invention further provides related chimeric molecules, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions. Methods of treating or preventing cancer in a mammal, methods of inhibiting the growth of a target cell, methods of producing the PE, and methods of producing the chimeric molecule are further provided by the invention. |
FILED | Friday, October 30, 2015 |
APPL NO | 14/927645 |
ART UNIT | 1676 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/164 (20130101) A61K 47/48484 (20130101) Peptides C07K 14/21 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 16/1214 (20130101) C07K 16/2851 (20130101) C07K 16/2896 (20130101) C07K 2317/34 (20130101) C07K 2317/56 (20130101) C07K 2317/622 (20130101) C07K 2319/01 (20130101) C07K 2319/55 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657073 | Distelhorst et al. |
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FUNDED BY |
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APPLICANT(S) | Clark Distelhorst (Shaker Heights, Ohio); Yiping Rong (Baoshan, China PRC) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Clark Distelhorst (Shaker Heights, Ohio); Yiping Rong (Baoshan, China PRC) |
ABSTRACT | A protease resistant polypeptide includes an amino acid sequence that has a sequence identity at least 80% homologous to about 10 to 80 consecutive amino acids of SEQ ID NO:1. |
FILED | Thursday, September 01, 2011 |
APPL NO | 13/819980 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) A61K 45/06 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4703 (20130101) Original (OR) Class C07K 14/4747 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657075 | Mohammadi et al. |
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FUNDED BY |
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APPLICANT(S) | New York University (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York) |
ABSTRACT | The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and the C-terminus includes a C-terminal portion of an FGF23 molecule. The portion of the paracrine FGF is modified to decrease binding affinity for heparin and/or heparan sulfate compared to the portion without the modification. The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, methods for treating a subject suffering from a disorder, and methods of screening for compounds with enhanced binding affinity for the αKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/839051 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1825 (20130101) A61K 38/1825 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657077 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Shulin Li (Houston, Texas); Jeffry Cutrera (Houston, Texas); Xueqing Xia (Houston, Texas) |
ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE (, None); UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
INVENTOR(S) | Shulin Li (Houston, Texas); Jeffry Cutrera (Houston, Texas); Xueqing Xia (Houston, Texas) |
ABSTRACT | A mini-peptide and its analogs have been found to target gene products to tumors. The peptide, named Carcinoma Homing Peptide (CHP), increased the tumor accumulation of the reporter gene products in five independent tumor models, including one human xenogeneic model. A CHP-IL-12 fusion gene was also developed using CHP and the p40 subunit of IL-12. The product from CHP-IL-12 fusion gene therapy increased accumulation of IL-12 in the tumor environment. In three tumor models, CHP-IL-12 gene therapy inhibited distal tumor growth. In a spontaneous lung metastasis model, inhibition of metastatic tumor growth was improved compared to wild-type IL-12 gene therapy, and in a squamous cell carcinoma model, toxic liver lesions were reduced. The receptor for CHP was identified as vimentin. CHP can be used to improve the efficacy and safety of targeted cancer treatments. |
FILED | Thursday, February 09, 2012 |
APPL NO | 13/370011 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/208 (20130101) Peptides C07K 7/06 (20130101) C07K 14/5434 (20130101) Original (OR) Class C07K 2319/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 33/57419 (20130101) G01N 33/57423 (20130101) G01N 33/57492 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657078 | Castillo et al. |
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FUNDED BY |
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APPLICANT(S) | PharmaIN Corporation (Bothell, Washington) |
ASSIGNEE(S) | PHARMAIN CORPORATION (Bothell, Washington) |
INVENTOR(S) | Gerardo M. Castillo (Bothell, Washington); Elijah Bolotin (Bothell, Washington) |
ABSTRACT | The invention describes compositions of peptide analogs that are active in blood or cleavable in blood to release an active peptide. The peptide analogs have a general formula: A-(Cm)x-Peptide (SEQ ID NO: 76), wherein A is hydrophobic moiety or a metal binding moiety, e.g., a chemical group or moiety containing 1) an alkyl group having 6 to 36 carbon units, 2) a nitrilotriacetic acid group, 3) an imidiodacetic acid group, or 4) a moiety of formula (ZyHisw)p (SEQ ID NO: 50), wherein Z is any amino acid residue other than histidine, His is histidine, y is an integer from 0-6; w is an integer from 1-6; and p is an integer from 1-6; wherein if A has alkyl group with 6 to 36 carbon units x is greater than 0; and Cm is a cleavable moiety consisting of glycine or alanine or lysine or arginine or N-Arginine or N-lysine, wherein x is an integer between 0-6 and N may be any amino acid or none. The peptide analogs are complexed with polymeric carrier to provide enhanced half-life. |
FILED | Monday, June 15, 2015 |
APPL NO | 14/739312 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/48038 (20130101) Peptides C07K 7/16 (20130101) C07K 14/485 (20130101) C07K 14/575 (20130101) C07K 14/57563 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657096 | Dimitrov et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Dimiter S. Dimitrov (Frederick, Maryland); Weizao Chen (Frederick, Maryland) |
ABSTRACT | Antibodies and antibody fragments that bind to insulin-like growth factor (IGF) 1 receptor (IGF-1R) or IGF-2, as well as methods of using the antibodies for inhibiting the IGF-mediated signaling pathway, inhibiting IGF-1R signaling, and treating cancer, are described. A method of detecting the presence of IGF-1R or IGF-2 in a sample using the disclosed antibodies and antibody fragments is also described. |
FILED | Wednesday, May 13, 2015 |
APPL NO | 14/710875 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39591 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/22 (20130101) Original (OR) Class C07K 16/2863 (20130101) C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 2333/71 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657101 | Ravetch et al. |
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FUNDED BY |
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APPLICANT(S) | The Rockefeller University (New York, New York) |
ASSIGNEE(S) | The Rockefeller University (New York, New York) |
INVENTOR(S) | Jeffrey V. Ravetch (New York, New York); Rene G. Ott (New York, New York) |
ABSTRACT | The present invention provides reagents, methods and systems for predicting the inhibitory activity of an antibody or variant thereof comprising: determining a binding affinity of the antibody or variant thereof to a Fc activating receptor; determining a binding affinity of the antibody or variant thereof to a Fc inhibitory receptor, and calculating the ratio of said activating binding affinity to said inhibitory binding affinity (A/I ratio), wherein the magnitude of said ratio is less than one (1). |
FILED | Tuesday, December 03, 2013 |
APPL NO | 14/095542 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657103 | Torres et al. |
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FUNDED BY |
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APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Victor J. Torres (New York, New York); Ashley L. Dumont (New York, New York) |
ABSTRACT | The present invention relates to methods of treating and preventing Staphylococcus aureus infection and/or a condition resulting from a S. aureus infection a subject that involves administering a CD11b inhibitor. The present invention further relates to a non-human transgenic animal expressing human CD11b and its use in methods of identifying novel therapeutics for the treatment and prevention of Staphylococcus aureus infection and/or a condition resulting from a S. aureus infection. |
FILED | Friday, March 15, 2013 |
APPL NO | 14/398293 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1741 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/31 (20130101) C07K 14/473 (20130101) C07K 14/4354 (20130101) C07K 14/70553 (20130101) C07K 16/2845 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2319/21 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56938 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657105 | Forman et al. |
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FUNDED BY |
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APPLICANT(S) | Stephen Forman (Duarte, California); Armen Mardiros (Glendale, California); Christine E. Brown (Duarte, California); Uma Maheswara Rao Jonnalagadda (Troy, Michigan) |
ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | Stephen Forman (Duarte, California); Armen Mardiros (Glendale, California); Christine E. Brown (Duarte, California); Uma Maheswara Rao Jonnalagadda (Troy, Michigan) |
ABSTRACT | A family of chimeric antigen receptors (CARs) containing a CD123 specific scFv was developed to target different epitopes on CD123. In some embodiments, such a CD123 chimeric antigen receptor (CD123CAR) gene includes an anti-CD123 scFv region fused in frame to a modified IgG4 hinge region comprising an S228P substitution, an L235E substitution, and optionally an N297Q substitution; a costimulatory signaling domain; and a T cell receptor (TCR) zeta chain signaling domain. When expressed in healthy donor T cells (CD4/CD8), the CD123CARs redirect T cell specificity and mediated potent effector activity against CD123+ cell lines as well as primary AML patient samples. Further, T cells obtained from patients with active AML can be modified to express CD123CAR genes and are able to lyse autologous AML blasts in vitro. Finally, a single dose of 5.0×106 CAR123 T cells results in significantly delayed leukemic progression in mice. These results suggest that CD123CAR-transduced T cells may be used as an immunotherapy for the treatment of high risk AML. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/844048 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/2866 (20130101) Original (OR) Class C07K 2317/622 (20130101) C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657269 | Arya et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Bira Arya (Ellicott City, Maryland); Purevdorj B. Olkhanud (Parkville, Maryland); Monica Bodogai (Baltimore, Maryland) |
ABSTRACT | Regulatory B cells (tBreg) are disclosed herein. These regulatory B cells express CD25 (CD25+) a pan B cell marker such as B220 (B220+), and also express CD19 (CD19+). These regulatory B cells suppress resting and activated T cells in cell contact-dependent manner. Methods for generating these regulatory B cells are also disclosed herein, as are methods for using these regulatory B cells to produce regulatory T cells (Treg). In some embodiments, methods for treating an immune-mediated disorder, such as an autoimmune disease, transplant rejection, graft-versus-host disease or inflammation, are disclosed. These methods include increasing regulatory B cell number or activity and/or by administering autologous regulatory B cells. Methods for treating cancer are also disclosed herein. These methods include decreasing regulatory B cell activity and/or number. |
FILED | Wednesday, November 25, 2015 |
APPL NO | 14/952768 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2035/122 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0635 (20130101) C12N 5/0637 (20130101) Original (OR) Class C12N 2502/30 (20130101) C12N 2502/1107 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657272 | Schlegel et al. |
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FUNDED BY |
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APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
INVENTOR(S) | Richard Schlegel (Rockville, Maryland); Xuefeng Liu (Gaithersburg, Maryland) |
ABSTRACT | The present invention is directed towards methods of culturing non-keratinocyte epithelial cells, with the methods comprising culturing non-keratinocyte epithelial cells in the presence of feeder cells and a calcium-containing medium while inhibiting the activity of Rho kinase (ROCK) in the feeder cell, the non-keratinocyte epithelial cells or both during culturing. |
FILED | Friday, September 26, 2014 |
APPL NO | 14/498089 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) C12N 5/0625 (20130101) C12N 5/0631 (20130101) C12N 5/0683 (20130101) Original (OR) Class C12N 5/0688 (20130101) C12N 2500/05 (20130101) C12N 2500/40 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/33 (20130101) C12N 2501/39 (20130101) C12N 2501/727 (20130101) C12N 2502/13 (20130101) C12N 2502/1323 (20130101) C12N 2503/02 (20130101) C12N 2510/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657292 | Rivera et al. |
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FUNDED BY |
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APPLICANT(S) | Juan Rivera (Mechanicsburg, Pennsylvania); Nicolas Charles (Asnieres sur Seine, France) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Juan Rivera (Mechanicsburg, Pennsylvania); Nicolas Charles (Asnieres sur Seine, France) |
ABSTRACT | The invention features compositions comprising agents that inhibit or reduce self-reactive IgE and/or basophils, and related methods of using the compositions for treating or preventing lupus, lupus nephritis, and lupus-related disorders. |
FILED | Wednesday, November 24, 2010 |
APPL NO | 13/989744 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) A61K 31/5383 (20130101) A61K 31/5383 (20130101) A61K 39/395 (20130101) A61K 39/39533 (20130101) A61K 39/39566 (20130101) A61K 39/39566 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/4291 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657350 | Elenitoba-Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Kojo Elenitoba-Johnson (Ann Arbor, Michigan); Thirunavukkarasu Velusamy (Ann Arbor, Michigan); Nallasivam Palanisamy (Ann Arbor, Michigan); Anagh Sahasrabuddhe (Ann Arbor, Michigan); Megan Lim (Ann Arbor, Michigan); Arul Chinnaiyan (Plymouth, Michigan) |
ABSTRACT | Provided herein are kits, compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent RNA fusions as diagnostic markers and clinical targets for leukemia. |
FILED | Tuesday, May 06, 2014 |
APPL NO | 14/271175 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57426 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657361 | Munoz-Jordan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Dept of Health and Human Services (Washington, District of Columbia); Jorge L. Munoz-Jordan (Puerto Rico, Puerto Rico); Edgardo Vergne (Sabanera, Puerto Rico); Gilberto Santiago (Guaynabo, Puerto Rico) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Jorge L. Munoz-Jordan (Puerto Rico, Puerto Rico); Edgardo Vergne (Sabanera, Puerto Rico); Gilberto Santiago (Guaynabo, Puerto Rico) |
ABSTRACT | Processes for detecting Dengue virus (DENV) nucleic acid in a sample are provided including producing an amplification product by amplifying DENV nucleotide sequence and detection of an amplification by hybridization of a probe or other technique. The processes use primers or probes with introduced mutations and or degenerate bases that provide excellent superiority in detection and serotyping of DENV in a sample. |
FILED | Thursday, October 25, 2012 |
APPL NO | 14/354972 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/701 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658060 | Molnar et al. |
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FUNDED BY |
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APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Alyosha Molnar (Ithaca, New York); Albert Wang (Ithaca, New York); Patrick Gill (Sunnyvale, California) |
ABSTRACT | An angle-sensitive pixel (ASP) device that uses the Talbot effect to detect the local intensity and incident angle of light includes a phase grating disposed above a photodiode assembly or a phase grating disposed above an analyzer grating that is disposed above a photodiode assembly. When illuminated by a plane wave, the upper grating generates a self-image at a selected Talbot depth. Several such structures, tuned to different incident angles, are sufficient to extract local incident angle and intensity. Arrays of such structures are sufficient to localize light sources in three dimensions without any additional optics. |
FILED | Monday, August 18, 2014 |
APPL NO | 14/462039 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/14 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 2201/062 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/782 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1446 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658139 | Hering et al. |
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FUNDED BY |
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APPLICANT(S) | TSI Incorporated (Shoreview, Minnesota) |
ASSIGNEE(S) | TSI INCORPORATED (Shoreview, Minnesota); AEROSOL DYNAMICS INC. (Berkley, California) |
INVENTOR(S) | Susanne V. Hering (Berkeley, California); Gregory S. Lewis (Berkeley, California); Arantzazu Eiguren Fernandez (El Cerrito, California); Frederick Quant (Shoreview, Minnesota); Kenneth R. Farmer, II (Lake Elmo, Minnesota) |
ABSTRACT | A system and a method is described herein for the collection of small particles in a concentrated manner, whereby particles are deposited onto a solid surface or collected into a volume of liquid. The collected samples readily interface to any of a number of different elemental, chemical, or biological or other analysis techniques. |
FILED | Wednesday, August 28, 2013 |
APPL NO | 14/012818 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2202 (20130101) Original (OR) Class G01N 1/2208 (20130101) G01N 1/2211 (20130101) G01N 15/065 (20130101) G01N 2001/2217 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658142 | Richardson et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | David Richardson (Chandler, Arizona); Thai Tran (Phoenix, Arizona); Dmitry Derkach (Gilbert, Arizona); Colleen Ziegler (Tempe, Arizona) |
ABSTRACT | Methods and apparatuses are provided for extraction and collection of sets of one or more cells from a formalin-fixed paraffin embedded tissue sample. A laser is used to remove sets of one or more cells from an immobilized sample within a microfluidic device, and a fluid flow element washes the removed set of one or more cells away from the immobilized sample, preferably to be collected in a downstream sample collection device. Morphological and/or positional information may be preserved to permit at least one technique (e.g., amplification, sequencing, and/or analytical, optionally performed after cells are lysed downstream of the microfluidic device) to be related to the original spatial location of the set of one or more cells in the immobilized sample. |
FILED | Thursday, April 14, 2016 |
APPL NO | 15/099121 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) Original (OR) Class G01N 2001/2886 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658222 | Moll et al. |
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FUNDED BY |
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APPLICANT(S) | MBIO DIAGONISTICS, INC. (Boulder, Colorado) |
ASSIGNEE(S) | Mbio Diagnostics, Inc. (Boulder, Colorado) |
INVENTOR(S) | Kevin D. Moll (Boulder, Colorado); Kurt R. Vogel (Boulder, Colorado); Marie J. Delaney (Boulder, Colorado); Michael J. Lochhead (Boulder, Colorado); Christopher J. Myatt (Boulder, Colorado) |
ABSTRACT | A cartridge for processing a sample includes (a) a planar waveguide with upper and lower planar surfaces defining an optical axis therebetween, wherein the upper planar surface has a plurality of capture molecules bound thereto, (b) a lens portion, coupled to the planar waveguide, for focusing and refracting a light beam propagating parallel to, but offset from, the optical axis such that the light beam couples into the planar waveguide and propagates therein along the optical axis at a non-zero, internal propagation angle β relative to the upper planar surface, and (c) a sample chamber for positioning the sample in contact with the plurality of capture molecules such that a target analyte of the sample is detectable through (i) an assay involving the target analyte and the capture molecules and (ii) evanescent illumination of the assay using the light beam within the planar waveguide. |
FILED | Monday, December 14, 2015 |
APPL NO | 14/968583 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 3/502715 (20130101) B01L 9/52 (20130101) B01L 2300/0636 (20130101) B01L 2300/0654 (20130101) B01L 2300/0825 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/648 (20130101) G01N 21/6452 (20130101) G01N 21/7703 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 2021/6439 (20130101) G01N 2201/0221 (20130101) G01N 2201/0612 (20130101) Optical Elements, Systems, or Apparatus G02B 6/003 (20130101) G02B 6/0095 (20130101) G02B 6/4291 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658224 | Siegel et al. |
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FUNDED BY |
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APPLICANT(S) | Donald Siegel (Philadelphia, Pennsylvania); Carlos F. Barbas, III (Solana Beach, California) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); The Scripps Research Insitute (La Jolla, California) |
INVENTOR(S) | Donald Siegel (Philadelphia, Pennsylvania); Carlos F. Barbas, III (Solana Beach, California) |
ABSTRACT | The present invention relates to novel methods for detecting a member of a known binding pair in a sample, including a cell, where one member of the pair (termed the “receptor”) is expressed by a bacteriophage, which phage is then used to detect the presence of the other member of the pair (termed the “ligand” or “target”). Rather than detecting the binding of the phage using antibody-based technology, the present invention relates to detecting marker molecule associated with the phage. In one aspect, the invention relates to identifying an antigen-bearing moiety (e.g., a red blood cell antigen) of interest present on a cell, e.g., a red blood cell, using antibody-displaying bacteriophage, as well as detecting anti-red blood cell auto- or alloantibodies and/or complement in a sample, using antiglobulin reagent-displaying bacteriophage and detecting a marker molecule associated with the phage. In one aspect, the phenotype of the phage is not linked with the genotype of the phage. |
FILED | Tuesday, November 14, 2006 |
APPL NO | 12/085618 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/555 (20130101) Original (OR) Class G01N 33/6854 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658228 | Miklos et al. |
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FUNDED BY |
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APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland University Junior University (Palo Alto, California) |
INVENTOR(S) | David B. Miklos (Stanford, California); Bita Sahaf (Palo Alto, California); Leonore A. Herzenberg (Stanford, California) |
ABSTRACT | The described invention comprises a method for detecting the onset or monitoring the recurrence of chronic graft versus host disease (cGVHD) in a transplantation patient. The method comprises isolating peripheral blood mononuclear cells (PBMCs) from the transplantation patient and analyzing the isolated PBMCs to detect a biomarker specific for a donor cell. The detection of the biomarker is indicative of the onset or recurrence of cGVHD in the transplantation patient. |
FILED | Tuesday, March 12, 2013 |
APPL NO | 13/796344 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) Original (OR) Class G01N 2333/70503 (20130101) G01N 2800/245 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658233 | Baron et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey Baron (North Potomac, Maryland); Youn Hee Jee (Bethesda, Maryland) |
ABSTRACT | The invention provides methods and kits for diagnosing a growth in a subject by providing a sample of a growth taken from a subject, determining the level of midkine or pleiotrophin in the sample by an immunoassay, and comparing the level of midkine or pleiotrophin determined from the sample with a control. An increased level of midkine or pleiotrophin in the sample as compared to the control is diagnostic of a malignant growth, whereas an equivalent or decreased level of midkine or pleiotrophin in the sample as compared to the control is diagnostic of a benign growth. |
FILED | Friday, February 17, 2017 |
APPL NO | 15/435880 |
ART UNIT | 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/543 (20130101) G01N 33/57488 (20130101) Original (OR) Class G01N 2333/475 (20130101) G01N 2800/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658470 | Applegate et al. |
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FUNDED BY |
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APPLICANT(S) | Raymond A. Applegate (Houston, Texas); Jason D. Marsack (Houston, Texas); Konrad Pesudovs (Gleneig, Australia); Yue Shi (Houston, Texas) |
ASSIGNEE(S) | University of Houston System (Houston, Texas) |
INVENTOR(S) | Raymond A. Applegate (Houston, Texas); Jason D. Marsack (Houston, Texas); Konrad Pesudovs (Gleneig, Australia); Yue Shi (Houston, Texas) |
ABSTRACT | Provided herein is a computer program product comprising a non-transitory computer-readable medium storing an algorithm to optimize a wavefront guided correction for a custom ophthalmic lens. The correction is determined from inputs of quantified wavefront error and registration uncertainty and a metric predictive of a visual performance task of interest and provides a level of visual performance within a user-defined performance range. Also provided is a method for optimizing a wavefront guided correction for a custom ophthalmic lens via inputting residual wavefront error values and quantified translational and rotational movements into an algorithm configured to determine the optimal wavefront guided correction therefrom and a custom ophthalmic lens comprising the correction. |
FILED | Thursday, February 27, 2014 |
APPL NO | 14/191902 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/04 (20130101) Original (OR) Class G02C 7/027 (20130101) G02C 2202/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659044 | Sarrafzadeh et al. |
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FUNDED BY |
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APPLICANT(S) | Majid Sarrafzadeh (Anaheim Hills, California); Jonathan S. Woodbridge (Los Angeles, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Majid Sarrafzadeh (Anaheim Hills, California); Jonathan S. Woodbridge (Los Angeles, California) |
ABSTRACT | A saliency function is computed to indicate the saliency of each of a plurality of data points in a dataset. For each local maximum in the saliency function, a segment of the dataset is inserted into an index. |
FILED | Thursday, July 19, 2012 |
APPL NO | 14/233091 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Electric Digital Data Processing G06F 17/30244 (20130101) G06F 17/30321 (20130101) Original (OR) Class G06F 17/30477 (20130101) Computer Systems Based on Specific Computational Models G06N 5/048 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659145 | Sayood et al. |
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FUNDED BY |
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APPLICANT(S) | Khalid Sayood (Lincoln, Nebraska); Sam Way (Boulder, Colorado); Ozkan Ufuk Nalbantoglu (Lincoln, Nebraska); George Garrity (Okemos, Michigan) |
ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska); NamesforLife, LLC (Lansing, Michigan) |
INVENTOR(S) | Khalid Sayood (Lincoln, Nebraska); Sam Way (Boulder, Colorado); Ozkan Ufuk Nalbantoglu (Lincoln, Nebraska); George Garrity (Okemos, Michigan) |
ABSTRACT | DNA sequences are analyzed using latent semantic analysis. A set of nucleotide sequences is received in which the set has a first number of sequences. A set of basis vectors is determined, in which the set has a second number of basis vectors, the second number being smaller than the first number. Each basis vector represents a specific combination of predetermined nucleotide segments. For each of the nucleotide sequences, an approximate representation of the nucleotide sequence is determined based on a combination of the basis vectors. For each pair of nucleotide sequences, a distance between the pair of nucleotide sequences is determined according the distance between the approximate representation of the pair of nucleotide sequences. The set of nucleotide sequences are classified based on the distances between the pairs of nucleotide sequences. |
FILED | Tuesday, July 30, 2013 |
APPL NO | 13/954925 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Electric Digital Data Processing G06F 19/22 (20130101) Original (OR) Class G06F 19/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659146 | Bray et al. |
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FUNDED BY |
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APPLICANT(S) | Tyler Stuart Bray (Chicago, Illinois); Juliesta Elaine Sylvester (Chicago, Illinois); Stephen Joseph Kron (Oak Park, Illinois) |
ASSIGNEE(S) | |
INVENTOR(S) | Tyler Stuart Bray (Chicago, Illinois); Juliesta Elaine Sylvester (Chicago, Illinois); Stephen Joseph Kron (Oak Park, Illinois) |
ABSTRACT | This invention is a novel method for analysis of data that is produced by test equipment. The preferred embodiment is data produced by liquid chromatography tandem mass spectrometry (LC-MS/MS) equipment, using industry standard methods to generate the initial data from the test equipment. The invention is a method for processing of the data to promptly produce accurate, reliable, and meaningful data that can be used for critical decisions. The unique benefit of the method is to correct the multiple measurement and calculation errors that are inherent in the operation of laboratory equipment. Prior methods result in errors based on circumstances that are difficult to control, accuracy-related errors in machine measurements, and fundamental mathematical errors in the data processing software that is used with the laboratory equipment. As an added benefit, this novel method allows comprehensive simultaneous measurement and calculation of correlation of any and all peptide pairs in a single measurement, with the capability to support repeated measurements with changed conditions over time. This novel method allows robust, detailed, and comprehensive measurements of peptide activity and function, which results in substantial improvements over prior methods in accuracy, reliability, and efficiency. |
FILED | Monday, May 02, 2011 |
APPL NO | 13/068026 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 2570/00 (20130101) Electric Digital Data Processing G06F 19/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659216 | Nikitin et al. |
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FUNDED BY |
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APPLICANT(S) | Alexei V. Nikitin (Lawrence, Kansas); Mark G. Frei (Oviedo, Florida); Naresh C. Bhavaraju (Lawrence, Kansas); Ivan Osorio (Leawood, Kansas); Ruslan L. Davidchack (Wigston, United Kingdom) |
ASSIGNEE(S) | Flint Hills Scientific, L.L.C. (Lawrence, Kansas) |
INVENTOR(S) | Alexei V. Nikitin (Lawrence, Kansas); Mark G. Frei (Oviedo, Florida); Naresh C. Bhavaraju (Lawrence, Kansas); Ivan Osorio (Leawood, Kansas); Ruslan L. Davidchack (Wigston, United Kingdom) |
ABSTRACT | A method, computer program, and system for real-time signal analysis providing characterization of temporally-evolving densities and distributions of signal features of arbitrary-type signals in a moving time window by tracking output of order statistic filters (also known as percentile, quantile, or rank-order filters). Given a raw input signal of arbitrary type, origin, or scale, the present invention enables automated quantification and detection of changes in the distribution of any set of quantifiable features of that signal as they occur in time. Furthermore, the present invention's ability to rapidly and accurately detect changes in certain features of an input signal can also enable prediction in cases where the detected changes associated with an increased likelihood of future signal changes. |
FILED | Monday, September 10, 2012 |
APPL NO | 13/608551 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Electric Digital Data Processing G06F 17/10 (20130101) G06F 17/18 (20130101) G06F 19/24 (20130101) G06F 19/345 (20130101) G06F 19/3437 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00536 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659351 | Aliaga et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
INVENTOR(S) | Daniel Gerardo Aliaga (West Lafayette, Indiana); Carlos Roberto Montalto Cruz (Seattle, Washington); Ignacio Garcia Dorado (West Lafayette, Indiana) |
ABSTRACT | A method to generate an output image that improves observation of a target image viewed on a medium by an optical system is disclosed. The method includes receiving at least one target image by a processing system, receiving at least one parameter by the processing system, defining an error signal associated with the difference between calculated optical system observation of intermediate images and the at least one target image, minimizing the error signal, and generating an output image associated with the intermediate image having the minimized error. |
FILED | Thursday, March 12, 2015 |
APPL NO | 14/656681 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/00 (20130101) A61B 3/032 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) Original (OR) Class G06T 5/003 (20130101) G06T 2207/20056 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659368 | Alsop et al. |
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FUNDED BY |
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APPLICANT(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | David Alsop (Newton, Massachusetts); Li Zhao (Cambridge, Massachusetts) |
ABSTRACT | Systems and methods for generating a medical image of a subject that includes functional information. First, two medical images are acquired. One is weighted based on functional information reflecting physiological functions of the subject and the other weighted based on anatomic information of the subject. A difference image between the two images are generated. By subjecting the difference image and the second image to a localized kernel, a local similarity image is generated. Using the local similarity image, an improved difference image is generated. Lastly, by subtracting the improved difference image from the first image, an enhanced medical image that retains the functional information reflecting physiological functions of the subject is generated. |
FILED | Friday, May 15, 2015 |
APPL NO | 14/714015 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/20221 (20130101) G06T 2207/30016 (20130101) G06T 2207/30104 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US RE46412 | Desjardins et al. |
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FUNDED BY |
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APPLICANT(S) | Adrien Desjardins (London, United Kingdom); Benjamin J. Vakoc (Arlington, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts) |
ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Adrien Desjardins (London, United Kingdom); Benjamin J. Vakoc (Arlington, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts) |
ABSTRACT | Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro-magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third electro-magnetic radiations can be simultaneously detected, with the signals being associated with information for the sample at a plurality of depths thereof. The depths can be determined using at least one of the third electro-magnetic radiations without a need to utilize another one of the third electro-magnetic radiations. |
FILED | Wednesday, February 19, 2014 |
APPL NO | 14/184537 |
ART UNIT | 3992 — Central Reexamination Unit (Electrical) |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02043 (20130101) G01B 9/02087 (20130101) G01B 9/02091 (20130101) G01B 2290/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4795 (20130101) Original (OR) Class G01N 2021/4714 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 09655521 | Iftimia et al. |
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FUNDED BY |
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APPLICANT(S) | Physical Sciences, Inc. (Andover, Massachusetts) |
ASSIGNEE(S) | Physical Sciences, Inc. (Andover, Massachusetts); Memorial Sloan-Kettering Cancer Center (New York, New York) |
INVENTOR(S) | Nicusor V. Iftimia (Chelmsford, Massachusetts); Mircea Mujat (Acton, Massachusetts); R. Daniel Ferguson (Melrose, Massachusetts); Ankit H. Patel (Methuen, Massachusetts); Milind Rajadhyaksha (New York, New York) |
ABSTRACT | A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path. |
FILED | Thursday, January 31, 2013 |
APPL NO | 13/755741 |
ART UNIT | 3737 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/0068 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655815 | Xiang et al. |
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FUNDED BY |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Rong Xiang (San Diego, California); He Zhou (San Diego, California); Ralph A Reisfeld (La Jolla, California) |
ABSTRACT | A DNA vaccine suitable for eliciting an immune response against cancer cells comprises a DNA construct operably encoding a cancer-associated Inhibitor of Apoptosis-family protein and an immunoactive gene product, such as a cytokine or a ligand for a natural killer cell surface receptor, in a pharmaceutically acceptable carrier. A preferred cytokine is CCL21. Preferred ligands for a natural killer cell surface receptor include human MICA, human MICB, human ULBP1, human ULBP2, and human ULBP3. The cancer-associated Inhibitor of Apoptosis (IAP)-family protein is preferably a survivin protein or livin protein. Method of inhibiting tumor growth by administering the vaccine of the invention to a mammal is also described. |
FILED | Monday, May 05, 2014 |
APPL NO | 14/269998 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/05 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 6/00 (20130101) A61K 39/0011 (20130101) A61K 2039/53 (20130101) A61K 2039/523 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655953 | Muro Galindo et al. |
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FUNDED BY |
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APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Silvia Muro Galindo (Silver Spring, Maryland); Vladimir R. Muzykantov (Bryn Athyn, Pennsylvania); Edward Howard Schuchman (Haworth, New Jersey) |
ABSTRACT | The present invention relates to compositions and methods for delivering lysosomal proteins. The compositions and methods described herein permit the targeted delivery of exogenous lysosomal proteins to cell surface proteins that allow their internalization via non-clathrin pathways. The present invention further relates to the use of the compositions and methods for enzyme replacement therapy of lysosomal storage diseases. Nucleic acids, recombinant cells and kits useful for making and using the compositions of the invention are also provided. |
FILED | Thursday, October 16, 2014 |
APPL NO | 14/516231 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 47/48561 (20130101) Peptides C07K 16/2821 (20130101) C07K 2317/77 (20130101) C07K 2319/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/04012 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) Y10T 428/2991 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655963 | Suzuki et al. |
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FUNDED BY |
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APPLICANT(S) | THE UAB RESEARCH FOUNDATION (Birmingham, Alabama); US ARMY WALTER REED ARMY MEDICAL CENTER, CHIEF, OFFICE OF RESEARCH, MARKETING and POLICY DEV (Washington, District of Columbia); JUNTENDO UNIVERSITY SCHOOL OF MEDICINE, DIVISION OF NEPHROLOGY, DEPARTMENT OF INTERNAL MEDICINE (Tokyo, Japan); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee) |
ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); US Army Walter Reed Army Medical Center, Chief, Office Of Research, Marketing and Policy Dev Walter Reed Army Institute of Research (Washington, District of Columbia); Juntendo University School of Medicine, Division of Nephrology, Department of Internal Medicine (Tokyo, Japan); University of Tennessee Research Foundation (Memphis, Tennessee) |
INVENTOR(S) | Hitoshi Suzuki (Hoover, Alabama); Run Fan (Omaha, Nebraska); Bruce A. Julian (Birmingham, Alabama); Jan Novak (Pelham, Alabama); Zina Moldoveanu (Birmingham, Alabama); Zhixin Zhang (Omaha, Nebraska); Milan Tomana (Birmingham, Alabama); Jiri Mestecky (Birmingham, Alabama); Robert J. Wyatt (Memphis, Tennessee); Yasuhiko Tomino (Tokyo, Japan); Yusuke Suzuki (Tokyo, Japan); Stephen Olson (Rockville, Maryland); Matthew B. Renfrow (Birmingham, Alabama) |
ABSTRACT | Provided are methods of diagnosing IgA nephropathy in a subject. Optionally, the methods comprise isolating an IgG from the subject and determining whether the IgG binds to a galactose-deficient IgA1. Optionally, the methods comprise providing a biological sample from the subject and detecting in the sample a mutation in a IGH gene, wherein the mutation is in a nucleotide sequence encoding a complementarity determining region 3 (CDR3) of a IGH variable region. Optionally, the methods comprise determining a level of IgG specific for a galactose-deficient IgA1 in the subject. Also provided are methods of treating or reducing the risk of developing IgA nephropathy in a subject. |
FILED | Friday, June 27, 2014 |
APPL NO | 14/318082 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39541 (20130101) Original (OR) Class Peptides C07K 16/4283 (20130101) C07K 2317/41 (20130101) C07K 2317/55 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/6893 (20130101) G01N 2800/347 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655967 | Gurtner et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Geoffrey C. Gurtner (Palo Alto, California); Michael T. Longaker (Stanford, California); Victor W. Wong (San Francisco, California) |
ABSTRACT | The formation of scars at a wound site is reduced by contacting the wound site with an effective dose of an inhibitor of focal adhesion kinase (FAK) activity or expression. Blockade of FAK is sufficient to prevent mechanical and inflammatory stimuli from activating MCP-1 pathways. In addition to these chemokine-mediated mechanisms, inhibition of FAK may control fibrosis by blocking fibroblast collagen production. Pharmacologic blockade of FAK significantly reduces scar formation in vivo. |
FILED | Wednesday, December 05, 2012 |
APPL NO | 13/706186 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656050 | Gregory et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon Biomedical Engineering Institute (Wilsonville, Oregon) |
ASSIGNEE(S) | Oregon Biomedical Engineering Institute (Wilsonville, Oregon) |
INVENTOR(S) | Kenton W. Gregory (Portland, Oregon); Lauryn L. Baranowski (Selah, Washington); Arjun Kalyanpur (Edison, New Jersey); Seanna Vine (Newburyport, Massachusetts); Grant Blackwell (Bristol, United Kingdom); Benjamin Margolis (San Bruno, California); Steven Dell (Carlsbad, California) |
ABSTRACT | Embodiments herein comprise a hemostatic composition comprising a plurality of liquid expandable articles capable of expanding upon contact with a liquid. A suitable composition comprises a plurality of liquid-expandable articles that may be mechanically uncoupled from one another and therefore may be capable of moving independently from one another. The plurality of liquid-expandable articles may comprise a compressed material capable of a high-degree of expansion upon liquid contact. |
FILED | Tuesday, September 02, 2014 |
APPL NO | 14/475281 |
ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00008 (20130101) A61F 13/00025 (20130101) A61F 13/00034 (20130101) A61F 13/36 (20130101) A61F 13/44 (20130101) A61F 13/00063 (20130101) A61F 2013/00106 (20130101) A61F 2013/00472 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/44 (20130101) A61L 15/425 (20130101) A61L 24/0015 (20130101) A61L 2300/44 (20130101) A61L 2300/418 (20130101) A61L 2400/04 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 29/02 (20130101) Original (OR) Class A61M 2205/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656290 | Ehrenberg et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia) |
INVENTOR(S) | Isaac M. Ehrenberg (Brookline, Massachusetts); Bae-Ian Wu (Beavercreek, Ohio); Sanjay Emani Sarma (Lexington, Massachusetts) |
ABSTRACT | A new 3D stencil mask guides deposition of a shaped structure, typically an electromagnetic device component, onto a non-planar surface. The 3D stencil mask includes islands and bridges from prior art two-dimensional lettering stencils, but raises the islands and stencils above the side of the 3D stencil mask facing a non-planar surface, forming undercuts, so that material particles, such as from vacuum metal deposition, will form connected shapes. The 3D stencil mask is also configures so that the dimensions of the resulting electromagnetic structures are altered from a simple projected image of a structure designed for a planar surface so that the electromagnetic properties of the deposited structure are more nearly the same as those of a corresponding structure on a planar surface. |
FILED | Monday, July 07, 2014 |
APPL NO | 14/325351 |
ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Apparatus for Applying Fluent Materials to Surfaces, in General B05C 21/005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656297 | Liu |
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FUNDED BY |
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APPLICANT(S) | Jiong Liu (East Brunswick, New Jersey) |
ASSIGNEE(S) | NEI Corporation (Somerset, New Jersey) |
INVENTOR(S) | Jiong Liu (East Brunswick, New Jersey) |
ABSTRACT | A pretreatment solution and process for pretreating steel substrates with an aqueous solution to form a thin partially crosslinked layer that passivates the steel surface and inhibits the formation of flash rust, in which the thin partially crosslinked layer is dried in ambient air, and the dried layer enhances the cathodic disbondment resistance of the overlying paint system. In the process an aqueous precursor solution (A) containing at least one amino-functional silane, at least one of a dissolved silicate or a dissolved aluminate and at least a metal salt; is mixed with an aqueous precursor solution (B) containing at least an epoxy resin. The molar amount of amino-functional silane in precursor solution (A) is at considerably lower than the stoichiometric amount that is needed for completing the crosslinking reaction with the epoxy resin in precursor solution (B) so that unreacted epoxy groups are made available for further crosslinking with the overlying paint. |
FILED | Monday, June 24, 2013 |
APPL NO | 13/924836 |
ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 5/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656704 | Couture et al. |
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FUNDED BY |
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APPLICANT(S) | iRobot Corporation (Bedford, Massachusetts) |
ASSIGNEE(S) | IROBOT DEFENSE HOLDINGS, INC. (Chelmsford, Massachusetts) |
INVENTOR(S) | Adam P. Couture (Allston, Massachusetts); Richard Page (Middleton, Massachusetts); John P. O'Brien (Newton, Massachusetts); Mikhail Filippov (Arlington, Massachusetts); Andrew Shein (Winchester, Massachusetts) |
ABSTRACT | A robotic vehicle (10,100,150A,150B150C,160,1000,1000A,1000B,1000C) includes a chassis (20,106,152,162) having front and rear ends (20A,152A,20B,152B) and supported on right and left driven tracks (34,44,108,165). Right and left elongated flippers (50,60,102,154,164) are disposed on corresponding sides of the chassis and operable to pivot. A linkage (70,156,166) connects a payload deck assembly (D1,D2,D3,80,158,168,806), configured to support a removable functional payload, to the chassis. The linkage has a first end (70A) rotatably connected to the chassis at a first pivot (71), and a second end (70B) rotatably connected to the deck at a second pivot (73). Both of the first and second pivots include independently controllable pivot drivers (72,74) operable to rotatably position their corresponding pivots (71,73) to control both fore-aft position and pitch orientation of the payload deck (D1,D2,D3,80,158,168,806) with respect to the chassis (20,106,152,162). |
FILED | Friday, May 16, 2014 |
APPL NO | 14/280123 |
ART UNIT | 3611 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 5/005 (20130101) B25J 11/0025 (20130101) Motor Vehicles; Trailers B62D 55/065 (20130101) B62D 55/075 (20130101) Original (OR) Class B62D 57/024 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656733 | Legg |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey D. Legg (Chula Vista, California) |
ABSTRACT | A life preserver locator system for assisting in locating and rescuing persons located in body of water. The life preserver locator system includes a water permeable envelope attachable to a life preserving aid and having a deployable water-activated signal assembly. In one embodiment, the deployable water-activated signal assembly includes a water-activated gas inflator mechanism that on exposure to water, such as saltwater, automatically actuates to inflate a balloon. The balloon deploys from the envelope into the air on a cable attached to the life preserver locator system allowing establishment of a line of sight from a person in the water and a rescue vessel to the balloon. In one embodiment, a light emitting device, such as strobe light, on the balloon automatically activates to emit light, to assist the person in the water in locating the life preserving aid. When the person reaches the life preserving aid, the person can activate a switch on the water-activated signal assembly changing the appearance of the emitted light. |
FILED | Monday, April 25, 2016 |
APPL NO | 15/137285 |
ART UNIT | 3617 — Electrical Circuits and Systems |
CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 9/18 (20130101) B63C 9/20 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656859 | Meyer et al. |
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FUNDED BY |
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APPLICANT(S) | David J. Meyer (Fairfax, Virginia); Brian P. Downey (Alexandria, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | David J. Meyer (Fairfax, Virginia); Brian P. Downey (Alexandria, Virginia) |
ABSTRACT | A process for fabricating a suspended microelectromechanical system (MEMS) structure comprising epitaxial semiconductor functional layers that are partially or completely suspended over a substrate. A sacrificial release layer and a functional device layer are formed on a substrate. The functional device layer is etched to form windows in the functional device layer defining an outline of a suspended MEMS device to be formed from the functional device layer. The sacrificial release layer is then etched with a selective release etchant to remove the sacrificial release layer underneath the functional layer in the area defined by the windows to form the suspended MEMS structure. |
FILED | Thursday, April 16, 2015 |
APPL NO | 14/687943 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00539 (20130101) Original (OR) Class B81C 2201/0107 (20130101) B81C 2201/0132 (20130101) B81C 2201/0143 (20130101) B81C 2201/0159 (20130101) B81C 2201/0177 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657024 | Punnonen et al. |
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FUNDED BY |
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APPLICANT(S) | STATegics, Inc. (South San Francisco, California) |
ASSIGNEE(S) | STATegics, Inc. (South San Francisco, California) |
INVENTOR(S) | Juha Punnonen (Belmont, California); Jeffrey R. Spencer (South San Francisco, California); Timothy J. Church (San Mateo, California); Connie S. Tettenborn (Belmont, California); Karen Lariosa-Willingham (Mountain View, California); Dmitri Leonoudakis (San Rafael, California); James L. Miller (Los Altos, California) |
ABSTRACT | Disclosed herein are erythropoietin-mimetic compounds of Formula I, which modulate the survival, function, or differentiation of, for example, kidney cells, neurons, erythroid cells, or other erythropoietin-responsive cells. The present invention also relates to compounds and methods that preferentially modulate cells expressing the tissue-protective erythropoietin receptor. The compounds of the invention are useful in preventing and treating diseases, such as anemia, organ injury, and diseases of the central nervous system, and as an adjunct to cellular treatments, such as stem cell therapies. |
FILED | Wednesday, November 20, 2013 |
APPL NO | 14/646651 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657145 | Sotzing et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
ASSIGNEE(S) | THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
INVENTOR(S) | Gregory Allen Sotzing (Storrs, Connecticut); Aaron Baldwin (Canterbury, Connecticut) |
ABSTRACT | Disclosed are transition metal or group II metal ester polymers where the metal is an alkaline earth, transition metal or aluminum; methods of manufacture, and uses thereof. The metal ester polymers exhibit both high dielectric constant and low conductivity suitable for use as dielectric insulating materials. |
FILED | Tuesday, November 24, 2015 |
APPL NO | 14/950940 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/00 (20130101) Original (OR) Class C08G 79/10 (20130101) C08G 79/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657484 | Lazzaro et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Matthew Lazzaro (Churchville, Maryland); William Toth (Ocean, New Jersey) |
ABSTRACT | Various embodiments are described that relate to a rapid deployment communications tile. As opposed to running various data and/or power wires, a construction crew can use set of tiles that have built in data and/or power transmission capabilities. These tiles can be keyed such that they interlock together to form a relatively uniform surface, such that the surface can also be used as a floor. Further, the tiles can have hardware components that enable the data and/or power transmission capabilities. These hardware components can be environmentally protected such that their performance is not subject to environmental factors. |
FILED | Thursday, February 12, 2015 |
APPL NO | 14/620707 |
ART UNIT | 3633 — Static Structures, Supports and Furniture |
CURRENT CPC | Finishing Work on Buildings, e.g Stairs, Floors E04F 15/105 (20130101) Original (OR) Class E04F 2201/095 (20130101) E04F 2201/098 (20130101) E04F 2290/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657642 | Kanjiyani et al. |
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FUNDED BY |
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APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morristown, New Jersey) |
ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
INVENTOR(S) | Shezan Kanjiyani (Glendale, Arizona); John Gintert (Tempe, Arizona); Rajiv Rana (Tempe, Arizona); Lorenzo Crosatti (Phoenix, Arizona); Bradley Reed Tucker (Chandler, Arizona); Ed Zurmehly (Phoenix, Arizona) |
ABSTRACT | A turbine section includes a stator assembly having an inner diameter end wall, an outer diameter end wall, and a stator vane; a turbine rotor assembly including a rotor blade extending into the mainstream gas flow path; a housing including an annular shroud that circumscribes the rotor blade and at least partially defines the mainstream hot gas flow path; a first baffle arranged to define a first cavity with the outer diameter end wall of the stator assembly; a second baffle; and a third baffle arranged to define a second cavity with the second baffle and a third cavity with the shroud. The first cavity is fluidly coupled to the second cavity and the second cavity is fluidly coupled to the third cavity such that cooling air flows from the first cavity to the second cavity and from the second cavity to the third cavity. |
FILED | Thursday, March 27, 2014 |
APPL NO | 14/227924 |
ART UNIT | 3748 — Static Structures, Supports and Furniture |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) F01D 11/08 (20130101) F01D 25/12 (20130101) F01D 25/14 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/10 (20130101) F02C 7/18 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2260/201 (20130101) F05D 2260/205 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657756 | Bostiga et al. |
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FUNDED BY |
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APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
INVENTOR(S) | Richard H. Bostiga (Ellington, Connecticut); Charles E. Reuter (Granby, Connecticut) |
ABSTRACT | An actuator system having various features is disclosed. An actuator system may have a first and a second electrohydraulic servo valve. A control selector may connect one of the electrohydraulic servo valves to a cylinder and may isolate the other electrohydraulic servo valve to ameliorate leakage in response to a switching solenoid valve operating. In this manner, one electrohydraulic servo valve may be connected to a cylinder to operate the cylinder, and the other electrohydraulic servo valve may be isolated from the cylinder, for example, to provide a standby electrohydraulic servo valve. |
FILED | Thursday, August 14, 2014 |
APPL NO | 14/460055 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 18/00 (20130101) Original (OR) Class F15B 20/005 (20130101) F15B 2211/30565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657884 | Carte et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | David B. Carte (Colorado Springs, Colorado); Marko Podplatnik (Ljubjana, Slovenia); Nathan Tangeman (Colorado Springs, Colorado); Nathan Davies (Colorado Springs, Colorado); Ryan Boedeker (Colorado Springs, Colorado); Kyle Fitle (Colorado Springs, Colorado); Christopher Caldrone (Colorado Springs, Colorado); Kelsey Brush (Colorado Springs, Colorado) |
ABSTRACT | A pipe crawler for crawling inside a pipe having an inside wall includes a front leg assembly that has front legs and feet. It also includes a rear leg assembly that has rear legs and feet. The rear leg assembly is disposed at a distance from the front leg assembly. A midsection operably couples the front leg assembly to the rear leg assembly and is configured to extend and contract the distance between the front leg assembly and the rear leg assembly. A plurality of lever arms are pivotably coupled between the front legs and their corresponding assemblies. The lever arms, in response to a force applied in an orientation traveling from the front of the pipe crawler to the rear of the pipe crawler, are configured to redirect a portion of the force into a normal force between the feet and the pipe inside wall. |
FILED | Monday, April 27, 2015 |
APPL NO | 14/697589 |
ART UNIT | 3617 — Fluid Handling and Dispensing |
CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 55/34 (20130101) F16L 55/44 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658040 | Vasudevan et al. |
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FUNDED BY |
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APPLICANT(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
INVENTOR(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
ABSTRACT | Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics. |
FILED | Tuesday, June 21, 2016 |
APPL NO | 15/188093 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Weapon Sights; Aiming F41G 7/222 (20130101) F41G 7/2293 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) F42B 10/42 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658087 | Baur et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey W. Baur (Liberty Township, Ohio); Matthew R. Maschmann (Columbia, Missouri); Gregory J. Ehlert (Miamisburg, Ohio); Benjamin T. Dickinson (Destin, Florida); David M. Phillips (Dayton, Ohio) |
ABSTRACT | A method for making an artificial hair sensor, comprising the steps of: (a) depositing an electrode at each end of a microcapillary having an inside surface; (b) coating a structural fiber with alumina; (c) placing the alumina coated structural fiber inside the microcapillary, wherein part of the alumina coated structural fiber is in a spaced annular relationship with the microcapillary inside surface and part of the fiber extends outside the microcapillary; (d) placing the microcapillary and alumina coated structural fiber inside a heated furnace chamber; and, (e) injecting a vaporized catalyst into the heated furnace chamber. The vaporized catalyst may be a solution of ferrocene in xylene. The microcapillary may be made of glass. |
FILED | Wednesday, May 06, 2015 |
APPL NO | 14/705944 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/56 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658105 | Bayya et al. |
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FUNDED BY |
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APPLICANT(S) | Shyam S. Bayya (Ashburn, Virginia); Daniel J. Gibson (Cheverly, Maryland); Vinh Q. Nguyen (Fairfax, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Jay Vizgaitis (Alexandria, Virginia) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
INVENTOR(S) | Shyam S. Bayya (Ashburn, Virginia); Daniel J. Gibson (Cheverly, Maryland); Vinh Q. Nguyen (Fairfax, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Jay Vizgaitis (Alexandria, Virginia) |
ABSTRACT | A compact multispectral imaging system comprising a set of optical elements capable of simultaneously focusing light from one or more spectral bands (SWIR, MWIR, and LWIR) to a common focal plane and a detector capable of capturing the multispectral image, wherein the optical elements comprise optics made from new optical materials or in combination with existing optical materials that transmit in multispectral wavelength regions. |
FILED | Wednesday, September 09, 2015 |
APPL NO | 14/848555 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0208 (20130101) G01J 3/2823 (20130101) Original (OR) Class G01J 2003/2826 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658139 | Hering et al. |
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FUNDED BY |
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APPLICANT(S) | TSI Incorporated (Shoreview, Minnesota) |
ASSIGNEE(S) | TSI INCORPORATED (Shoreview, Minnesota); AEROSOL DYNAMICS INC. (Berkley, California) |
INVENTOR(S) | Susanne V. Hering (Berkeley, California); Gregory S. Lewis (Berkeley, California); Arantzazu Eiguren Fernandez (El Cerrito, California); Frederick Quant (Shoreview, Minnesota); Kenneth R. Farmer, II (Lake Elmo, Minnesota) |
ABSTRACT | A system and a method is described herein for the collection of small particles in a concentrated manner, whereby particles are deposited onto a solid surface or collected into a volume of liquid. The collected samples readily interface to any of a number of different elemental, chemical, or biological or other analysis techniques. |
FILED | Wednesday, August 28, 2013 |
APPL NO | 14/012818 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2202 (20130101) Original (OR) Class G01N 1/2208 (20130101) G01N 1/2211 (20130101) G01N 15/065 (20130101) G01N 2001/2217 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658314 | Parks et al. |
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FUNDED BY |
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APPLICANT(S) | Brandon Scott Parks (South Park, Pennsylvania); Walter J. Keller, III (Bridgeville, Pennsylvania); Jennting Timothy Hsu (Bethel Park, Pennsylvania) |
ASSIGNEE(S) | Nokomis, Inc. (Charleroi, Pennsylvania) |
INVENTOR(S) | Brandon Scott Parks (South Park, Pennsylvania); Walter J. Keller, III (Bridgeville, Pennsylvania); Jennting Timothy Hsu (Bethel Park, Pennsylvania) |
ABSTRACT | A system for identifying a real-world geographic location of an emission source emitting electromagnetic energy includes a platform configured for movement and an apparatus disposed on the platform and configured to collect and process, in a passive manner and during movement of the platform, at least a pair of successive samples of the electromagnetic energy emission and define angular and spatial coordinates of the emission source. The apparatus includes at least a pair of antennas, a receiver coupled to antennas and a processor executing a predetermined logic. |
FILED | Friday, March 02, 2012 |
APPL NO | 13/410586 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/04 (20130101) Original (OR) Class G01S 5/0221 (20130101) G01S 5/0278 (20130101) G01S 5/0284 (20130101) G01S 5/0294 (20130101) G01S 19/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658318 | Forero et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED STATED OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
INVENTOR(S) | Pedro A. Forero (San Diego, California); Paul A. Baxley (San Diego, California) |
ABSTRACT | A system and a method involve acoustic source localization for multiple acoustic sources using passive sonar. Tracks are constructed based on source location maps (SLMs) that reveal the locations of the sources over a grid of tentative source locations. The proposed estimator for the SLMs performs coherent processing of broadband acoustic measurements, capitalizes on the sparse structure of the SLMs, and uses the prior SLM estimate to capture temporal information about the locations of the sources. |
FILED | Wednesday, January 27, 2016 |
APPL NO | 15/008322 |
ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/808 (20130101) G01S 5/18 (20130101) G01S 5/22 (20130101) Original (OR) Class G01S 15/04 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/001 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/44 (20130101) H04R 1/406 (20130101) H04R 3/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658398 | Budd et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Russell A. Budd (North Salem, New York); Daniel M. Kuchta (Patterson, New York); Benjamin Giles Lee (New York, New York); Laurent Schares (Sleepy Hollow, New York); Clint Lee Schow (Ossining, New York) |
ABSTRACT | A system comprises a first optical component comprising at least one waveguide and at least one self-alignment feature; and a second optical component comprising at least another waveguide and at least another self-alignment feature; wherein the self-alignment feature of the second optical component engage to assist in optically-coupling the waveguide of the first optical component and the waveguide of the second optical component when the first optical component has a manufacturing tolerance in a given geometric dimension and is mounted in the second optical component. |
FILED | Tuesday, April 12, 2016 |
APPL NO | 15/096996 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 6/423 (20130101) G02B 6/3652 (20130101) G02B 2006/12119 (20130101) G02B 2006/12166 (20130101) G02B 2006/12173 (20130101) G02B 2006/12176 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658404 | Ohnstein et al. |
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FUNDED BY |
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APPLICANT(S) | Honeywell International Inc. (Morristown, New Jersey) |
ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
INVENTOR(S) | Thomas Ohnstein (Roseville, Minnesota); Daniel Youngner (Maple Grove, Minnesota); Mary Salit (Plymouth, Minnesota); Jeff A. Ridley (Shorewood, Minnesota) |
ABSTRACT | Methods, apparatuses, and systems for design, fabrication, and use of an optical bench, as well as alignment and attachment of optical fibers are described herein. One apparatus includes an apparatus body, a first channel within the apparatus body for positioning of a first optical fiber directed along a first axis and a second channel within the apparatus body for positioning of a second optical fiber directed along a second axis, wherein the first axis is orthogonal to the second axis. The apparatus also includes a third optical fiber directed along the second axis and an optical element positioned along the first channel and second channel to focus a first light beam from the first optical fiber along the first axis and focus a second light beam from the second optical fiber along the second axis. |
FILED | Tuesday, April 14, 2015 |
APPL NO | 14/686501 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/32 (20130101) G02B 6/3616 (20130101) G02B 6/3636 (20130101) G02B 6/3652 (20130101) Original (OR) Class G02B 6/3664 (20130101) G02B 6/3692 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658510 | Kippelen et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Bernard Kippelen (Atlanta, Georgia); Canek Fuentes-Hernandez (Atlanta, Georgia); James June Fan Hsu (Atlanta, Georgia) |
ABSTRACT | An optical device capable of an ultrafast and large change of its reflection or absorption coefficient upon being excited by an ultrafast optical pulse with wavelength in the visible, near-infrared, or infrared spectral regions. The optical device includes, in sequential order, a first thick metallic layer, a first dielectric layer, a second thin metallic layer, and a second dielectric layer. The optical device acts as a nonlinear mirror that presents a large reflectance at low irradiance and a low reflectance at large irradiance. The optical device can further act as a nonlinear mirror that presents a linear and nonlinear reflectance with a large angular bandwidth. |
FILED | Friday, December 20, 2013 |
APPL NO | 14/764100 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/17 (20130101) G02F 1/19 (20130101) G02F 1/21 (20130101) Original (OR) Class G02F 1/0126 (20130101) G02F 1/355 (20130101) G02F 1/3523 (20130101) G02F 2001/211 (20130101) G02F 2203/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658512 | Tabirian et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia); Beam Engineering for Advanced Measurements Co. (Orlando, Florida) |
ASSIGNEE(S) | Beam Engineering for Advanced Materials Co. (Orlando, Florida); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Nelson V. Tabirian (Winter Park, Florida); Sarik R. Nersisyan (Winter Park, Florida); Brian R. Kimball (Shrewsbury, Massachusetts); Diane M. Steeves (Franklin, Massachusetts) |
ABSTRACT | A cycloidal diffractive waveplate (50) comprising first and second substrate layers (52, 54), a liquid crystal layer (60C, 60H) provided between the first and second substrate layers, and transparent positive electrodes (56) and transparent negative electrodes (58) provided on the first substrate layer. The liquid crystal layer has a diffractive state (60C) in which the optical axes of the liquid crystal molecules are periodically rotated across a plane of the waveplate and a non-diffractive state (60H) in which the optical axes of the liquid crystal molecules are all orientated in the same direction in the plane of the waveplate. The electrodes (56, 58) are arranged in an alternating series, such that when an electric voltage is applied to the electrodes an electric field is produced in the plane of the waveplate and the liquid crystal layer is switched from the diffractive state to the non-diffractive state. A method of manufacturing the cycloidal diffractive waveplate is also provided. |
FILED | Tuesday, January 28, 2014 |
APPL NO | 14/165615 |
ART UNIT | 2871 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) Original (OR) Class G02F 1/134363 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49155 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658940 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Tong Chen (Yorktown Heights, New York); John Kevin O'Brien (South Salem, New York); Zehra Noman Sura (Yorktown Heights, New York) |
ABSTRACT | Software-managed resources are used to utilize effective-to-real memory address translation for synchronization among processes executing on processor cores in a multi-core computing system. A failure to find a pre-determined effective memory address translation in an effective-to-real memory address translation table on a first processor core triggers an address translation exception in a second processor core and causes an exception handler on the second processor core to start a new process, thereby acting as a means to achieve synchronization among processes on the first processor core and the second processor core. The specific functionality is implemented in the exception handler, which is tailored to respond to the exception based on the address that generated it. |
FILED | Thursday, March 19, 2015 |
APPL NO | 14/662789 |
ART UNIT | 2136 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 8/65 (20130101) G06F 8/751 (20130101) G06F 9/4552 (20130101) G06F 11/28 (20130101) G06F 11/073 (20130101) G06F 11/0772 (20130101) G06F 11/0793 (20130101) G06F 11/3632 (20130101) Original (OR) Class G06F 12/1027 (20130101) G06F 2212/684 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658987 | Avron et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Haim Avron (White Plains, New York); Kenneth L. Clarkson (Madison, New Jersey); Huy Le Nguyen (Princeton, New Jersey); David P. Woodruff (Mountain View, California) |
ABSTRACT | Embodiments of the invention relate to sketching for M-estimators for performing regression. One embodiment includes providing one or more sets of input data. A matrix A and a vector b are generated using the input data. A processor device is used for processing the matrix A and the vector b based on a randomized sketching matrix S. A vector x that minimizes a normalized measure function is determined based on the matrix A and the vector b. A relationship between the input data is determined based on the vector x. |
FILED | Thursday, May 15, 2014 |
APPL NO | 14/279177 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659189 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Wenke Lee (Atlanta, Georgia); Alexandra Boldyreva (Atlanta, Georgia); Chung Pak Ho (Atlanta, Georgia); Billy Lau (Atlanta, Georgia); Chengyu Song (Atlanta, Georgia) |
ABSTRACT | The disclosed technology includes techniques for improving data privacy in mobile communications over public cloud services. According to certain implementations, a novel conceptual layer may be interposed between the “application” layer and the “user” layer. In some implementations, the conceptual layer may be at least partially embodied by a transparent window or pane overlaid on top of existing app graphical user interfaces to: (1) intercept plaintext user input before transforming the input and feeding it to an underlying app; and (2) reverse transform output data from the app before displaying the plaintext data to the user. Accordingly, the conceptual layer may serve as a protective layer while preserving the original application workflow and look-and-feel. |
FILED | Tuesday, October 14, 2014 |
APPL NO | 14/513680 |
ART UNIT | 2492 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/6263 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0435 (20130101) Wireless Communication Networks H04W 12/00 (20130101) H04W 12/02 (20130101) H04W 88/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659257 | Hodgin |
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FUNDED BY |
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APPLICANT(S) | AlphaTRAC, Inc. (Westminster, Colorado) |
ASSIGNEE(S) | AlphaTRAC, Inc. (Westminster, Colorado) |
INVENTOR(S) | Charles Reed Hodgin (Westminster, Colorado) |
ABSTRACT | A method and system that provide for decision support and/or training support in crisis decision-making situations are provided. In one implementation, a method identifies patterns from known cases based on information from a crisis event. Each of the known cases includes attributes and at least one outcome. The method also identifies a first subset of the known cases that relate to the identified patterns from the known cases. The method also analyzes the identified patterns to determine a cue that, if answered, will provide a second subset of the known cases including a more converged range of decision outcomes than the first subset. |
FILED | Monday, February 25, 2013 |
APPL NO | 13/776486 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0454 (20130101) G06N 99/005 (20130101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 31/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659737 | Eden et al. |
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FUNDED BY |
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APPLICANT(S) | J. Gary Eden (Champaign, Illinois); Sung-Jin Park (Champaign, Illinois); JeKwon Yoon (Paju-Si, South Korea); Kwang-Soo Kim (Champaign, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | J. Gary Eden (Champaign, Illinois); Sung-Jin Park (Champaign, Illinois); JeKwon Yoon (Paju-Si, South Korea); Kwang-Soo Kim (Champaign, Illinois) |
ABSTRACT | Microstructured, irregular surfaces pose special challenges but coatings of the invention can uniformly coat irregular and microstructured surfaces with one or more thin layers of phosphor. Preferred embodiment coatings are used in microcavity plasma devices and the substrate is, for example, a device electrode with a patterned and microstructured dielectric surface. A method for forming a thin encapsulated phosphor coating of the invention applies a uniform paste of metal or polymer layer to the substrate. In another embodiment, a low temperature melting point metal is deposited on the substrate. Polymer particles are deposited on a metal layer, or a mixture of a phosphor particles and a solvent are deposited onto the uniform glass, metal or polymer layer. Sequential soft and hard baking with temperatures controlled to drive off the solvent will then soften or melt the lowest melting point constituents of the glass, metal or polymer layer, partially or fully embed the phosphor particles into glass, polymer, or metal layers, which partially or fully encapsulate the phosphor particles and/or serve to anchor the particles to a surface. |
FILED | Thursday, July 14, 2011 |
APPL NO | 13/183255 |
ART UNIT | 2879 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/222 (20130101) H01J 29/20 (20130101) Original (OR) Class H01J 61/44 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24421 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659824 | Cheng et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Joy Cheng (San Jose, California); Matthew E. Colburn (Schenectady, New York); Michael A. Guillorn (Yorktown Heights, New York); Chi-Chun Liu (Altamont, New York); Melia Tjio (San Jose, California); HsinYu Tsai (White Plains, New York) |
ABSTRACT | Guiding pattern portions are formed on a surface of a lithographic material stack that is disposed on a surface of a semiconductor substrate. A copolymer layer is then formed between each neighboring pair of guiding pattern portions and thereafter a directed self-assembly process is performed that causes phase separation of the various polymeric domains of the copolymer layer. Each guiding pattern portion is selectively removed, followed by the removal of each first phase separated polymeric domain. Each second phase separated polymeric domain remains and is used as an etch mask in forming semiconductor fins in an upper semiconductor material portion of the semiconductor substrate. |
FILED | Tuesday, April 28, 2015 |
APPL NO | 14/697693 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0273 (20130101) H01L 21/845 (20130101) H01L 21/3081 (20130101) H01L 21/3086 (20130101) H01L 21/823431 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660286 | McNeilly |
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FUNDED BY |
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APPLICANT(S) | Frank J. McNeilly (Portsmouth, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Frank J. McNeilly (Portsmouth, Rhode Island) |
ABSTRACT | An anode/cathode system is disclosed for use in a Benthic microbial fuel cell. Carbon cloth forms at least a portion of the anode and is disposed on one side of a water oxygen impermeable layer, which can be weighted around a periphery thereof to hold the anode against a water-sediment interface. Carbon cloth flaps or strands can be attached to the other side of the impermeable layer to form the cathode. The anode and cathode can be divided into sections with each section having an electrical lead coupled thereto. The system is deployed onto the seafloor with the anode side in contact with the water-sediment interface. |
FILED | Monday, March 24, 2014 |
APPL NO | 14/222771 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/02 (20130101) H01M 8/16 (20130101) Original (OR) Class H01M 2250/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660322 | Liu |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Yong Liu (San Marino, California) |
ABSTRACT | Apparatus, systems and methods provide for compensating for pointing errors that may occur when using a coarse positioning mechanism for pointing a payload toward a target. According to aspects of the disclosure, a coarse positioning mechanism is configured to compensate for pointing errors that may occur when pointing a payload toward a target over a large angular FOV. The coarse positioning mechanism may be configured for a variety of applications, such as precision tracking applications and precision pointing applications over a large angular FOV. The coarse positioning mechanism may include adjustment mechanisms for one or more axes that are used to adjust the pointing direction of the target. |
FILED | Tuesday, February 18, 2014 |
APPL NO | 14/182860 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/125 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660582 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Mahdi Jamali (Minneapolis, Minnesota) |
ABSTRACT | A device including a spin channel to transport a spin current, a nano-oscillator, and a magnetoresistive device that receives the spin current from the nano-oscillator. The nano-oscillator includes a magnetization state that oscillates between a first state and a second state in response to an input voltage or current. The oscillation of the nano-oscillator may induce the spin current within the spin channel. The magnetoresistive device includes a magnetization state that is set based at least in part on the received spin current. |
FILED | Friday, August 19, 2016 |
APPL NO | 15/241169 |
ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 25/00 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 5/3909 (20130101) G11B 5/3958 (20130101) G11B 2005/3996 (20130101) Static Stores G11C 11/161 (20130101) G11C 11/1673 (20130101) G11C 11/1675 (20130101) G11C 19/0808 (20130101) G11C 19/0841 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/3254 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/08 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 15/006 (20130101) Original (OR) Class Pulse Technique H03K 19/16 (20130101) H03K 19/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660654 | Matheny et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Matthew Matheny (Diamond Bar, California); Michael L. Roukes (Pasadena, California); Michael C. Cross (Arroyo Grande, California); Luis Guillermo Villanueva Torrijo (Los Angeles, California); Rassul Karabalin (Los Angeles, California) |
ABSTRACT | Synchronization of oscillators based on anharmonic nanoelectromechanical resonators. Experimental implimentation allows for unprecedented observation and control of parameters governing the dynamics of synchronization. Close quantitative agreement is found between experimental data and theory describing reactively coupled Duffing resonators with fully saturated feedback gain. In the synchonized state, a significant reduction in the phase noise of the oscillators is demonstrated, which is key for applications such as sensors and clocks. Oscillator networks constructed from nanomechanical resonators form an important laboratory to commercialize and study synchronization—given their high-quality factors, small footprint, and ease of co-integration with modern electronic signal processing technologies. Networks can be made including one-, two-, and three-dimensional networks. Triangular and square lattices can be made. |
FILED | Friday, October 25, 2013 |
APPL NO | 14/063905 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/11 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/30 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660757 | Beranek et al. |
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FUNDED BY |
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APPLICANT(S) | Mark Beranek (Hollywood, Maryland); Robert Boyd (St. Leonard, Maryland); Nicholas Peterson (Lexington Park, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Mark Beranek (Hollywood, Maryland); Robert Boyd (St. Leonard, Maryland); Nicholas Peterson (Lexington Park, Maryland) |
ABSTRACT | The present invention is directed to a low latency fiber optic local area network with a network and a plurality of nodes connected through optical fibers. Each node has a plurality of bi-directional input/output interfaces. Each bi-directional input/output interface has a demultiplexer, at least one optical power coupler, a plurality of wavelength converters, and a plurality of internal optical waveguides. The internal optical waveguides extend from each wavelength converter and are for communication with the demultiplexer, the input fiber optic interface, and the optical fiber. Each optical power coupler has a fiber optic output interface for communication with other nodes, and each demultiplexer has a input fiber optic interface for communication with other nodes. |
FILED | Tuesday, June 09, 2015 |
APPL NO | 14/734186 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Transmission H04B 10/272 (20130101) H04B 10/278 (20130101) Multiplex Communication H04J 14/028 (20130101) H04J 14/0282 (20130101) Original (OR) Class H04J 14/0284 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 09655573 | Majewski et al. |
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FUNDED BY |
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APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
ASSIGNEE(S) | WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia) |
INVENTOR(S) | Stanislaw Majewski (Charlottesville, Virginia); Julie Brefczynski-Lewis (Morgantown, West Virginia) |
ABSTRACT | Various methods, systems and apparatus are provided for brain imaging during virtual reality stimulation. In one example, among others, a system for virtual ambulatory environment brain imaging includes a mobile brain imager configured to obtain positron emission tomography (PET) scans of a subject in motion, and a virtual reality (VR) system configured to provide one or more stimuli to the subject during the PET scans. In another example, a method for virtual ambulatory environment brain imaging includes providing stimulation to a subject through a virtual reality (VR) system; and obtaining a positron emission tomography (PET) scan of the subject while moving in response to the stimulation from the VR system. The mobile brain imager can be positioned on the subject with an array of imaging photodetector modules distributed about the head of the subject. |
FILED | Tuesday, December 15, 2015 |
APPL NO | 14/969597 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/462 (20130101) A61B 6/466 (20130101) A61B 6/467 (20130101) A61B 6/501 (20130101) A61B 6/4405 (20130101) Original (OR) Class A61B 6/5205 (20130101) A61B 34/30 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656061 | Cela et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | The University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Carlos Jose Cela (Salt Lake City, Utah); Gianluca Lazzi (Salt Lake City, Utah) |
ABSTRACT | The present embodiments are directed to implantable electrode arrays having virtual electrodes. The virtual electrodes may improve the resolution of the implantable electrode array without the burden of corresponding complexity of electronic circuitry and wiring. In a particular embodiment, a virtual electrode may include one or more passive elements to help steer current to a specific location between the active electrodes. For example, a passive element may be a metalized layer on a substrate that is adjacent to, but not directly connected to an active electrode. In certain embodiments, an active electrode may be directly coupled to a power source via a conductive connection. Beneficially, the passive elements may help to increase the overall resolution of the implantable array by providing additional stimulation points without requiring additional wiring or driver circuitry for the passive elements. |
FILED | Friday, September 11, 2015 |
APPL NO | 14/852147 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0551 (20130101) Original (OR) Class A61N 1/0553 (20130101) A61N 1/36185 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656205 | Singh et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Surinder Prabhjot Singh (Schenectady, New York); Harish Radhakrishna Acharya (Clifton Park, New York); Robert James Perry (Niskayuna, New York); John Brian McDermott (Rexford, New York) |
ABSTRACT | A system and method for treatment of a medium is disclosed. The system includes a plurality of separator zones and a plurality of heat transfer zones. Each of the separator zone and the heat transfer zone among the plurality of separator zones and heat transfer zones respectively, are disposed alternatively in a flow duct. Further, each separator zone includes an injector device for injecting a sorbent into the corresponding separator zone. Within the corresponding separator zone, the injected sorbent is reacted with a gaseous medium flowing in the flow duct, so as to generate a reacted gaseous medium and a reacted sorbent. Further, each heat transfer zone exchanges heat between the reacted gaseous medium fed from the corresponding separator zone and a heat transfer medium. |
FILED | Friday, June 28, 2013 |
APPL NO | 13/931421 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/62 (20130101) Original (OR) Class B01D 53/78 (20130101) B01D 53/83 (20130101) B01D 53/343 (20130101) B01D 53/1406 (20130101) B01D 53/1475 (20130101) B01D 2252/2041 (20130101) B01D 2252/20421 (20130101) B01D 2252/20484 (20130101) B01D 2252/20489 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2259/65 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101) Y02C 10/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656243 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Donghai Wang (State College, Pennsylvania); Fang Dai (State College, Pennsylvania); Ran Yi (State College, Pennsylvania); Jianto Zai (State College, Pennsylvania) |
ABSTRACT | We provide a mesoporous silicon material (PSi) prepared via a template-free and HF-free process. The production process is facile and scalable, and it may be conducted under mild reaction conditions. The silicon may be produced directly by the reduction of a silicon-halogenide precursor (for example, SiCl4) with an alkaline alloy (for example, NaK alloy). The resulting Si-salt matrix is then annealed for the pore formation and crystallite growth. Final product is obtained by removal of the salt by-products with water. |
FILED | Thursday, July 10, 2014 |
APPL NO | 14/328136 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/06 (20130101) Original (OR) Class B01J 35/004 (20130101) B01J 35/1019 (20130101) B01J 35/1023 (20130101) B01J 35/1042 (20130101) B01J 35/1047 (20130101) B01J 35/1061 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/033 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) H01M 4/622 (20130101) H01M 4/623 (20130101) H01M 8/0606 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/324 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656728 | Mundon |
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FUNDED BY |
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APPLICANT(S) | Oscilla Power, Inc. (Seattle, Washington) |
ASSIGNEE(S) | Oscilla Power, Inc. (Seattle, Washington) |
INVENTOR(S) | Timothy R Mundon (Seattle, Washington) |
ABSTRACT | A system for transporting a buoy and a heave plate. The system includes a buoy and a heave plate. An outer surface of the buoy has a first geometrical shape. A surface of the heave plate has a geometrical shape complementary to the first geometrical shape of the buoy. The complementary shapes of the buoy and the heave plate facilitate coupling of the heave plate to the outer surface of the buoy in a transport mode. |
FILED | Friday, July 24, 2015 |
APPL NO | 14/808436 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/18 (20130101) B63B 22/20 (20130101) Original (OR) Class Hydraulic Engineering E02B 9/08 (20130101) Machines or Engines for Liquids F03B 13/20 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2230/60 (20130101) F05B 2260/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/34 (20130101) Dynamo-electric Machines H02K 7/1876 (20130101) Electric Machines Not Otherwise Provided for H02N 2/18 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656881 | Steinhour |
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FUNDED BY |
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APPLICANT(S) | Leif Alexi Steinhour (Berkeley, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Leif Alexi Steinhour (Berkeley, California) |
ABSTRACT | Systems, methods, and apparatus are provided for purifying and pumping liquids, and more particularly, for purifying and pumping water. The apparatus includes a chamber including a top portion and a bottom portion. A surface configured to be heated is proximate the bottom portion of the chamber. A baffle is disposed within the chamber and above the surface. The baffle is disposed at an angle relative to a vertical direction. The chamber further includes an inlet and a first outlet. The surface heats a liquid in the chamber, causing the liquid to boil. In operation, bubbles rise from the surface and are forced in a horizontal direction by the baffle disposed in the chamber. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/210226 |
ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Separation B01D 1/04 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/14 (20130101) Original (OR) Class C02F 1/325 (20130101) C02F 2201/3228 (20130101) C02F 2303/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656926 | Thoma et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Steven G. Thoma (Albuquerque, New Mexico); Mark C Grubelich (Albuquerque, New Mexico); Mathias C. Celina (Albuquerque, New Mexico); Mark R. Vaughn (Albuquerque, New Mexico); Steven D. Knudsen (Stanley, New Mexico) |
ABSTRACT | A self-consuming structure is disclosed that is formed from a self-consuming composition based on an epoxy or polyurethane having fuel and/or oxidizer molecularly dispersed and/or as particulates in the epoxy or polyurethane. The composition may be used to form self-consuming structural components. |
FILED | Wednesday, July 17, 2013 |
APPL NO | 13/943959 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/10 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 33/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656937 | Held et al. |
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FUNDED BY |
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APPLICANT(S) | Virent, Inc. (Madison, Wisconsin) |
ASSIGNEE(S) | Virent, Inc. (Madison, Wisconsin) |
INVENTOR(S) | Andrew Held (Madison, Wisconsin); Elizabeth Woods (Middleton, Wisconsin); Randy Cortright (Madison, Wisconsin); Matthew Gray (Highlands Ranch, Colorado) |
ABSTRACT | The present invention provides processes, methods, and systems for converting biomass-derived feedstocks to liquid fuels and chemicals. The method generally includes the reaction of a hydrolysate from a biomass deconstruction process with hydrogen and a catalyst to produce a reaction product comprising one of more oxygenated compounds. The process also includes reacting the reaction product with a condensation catalyst to produce C4+ compounds useful as fuels and chemicals. |
FILED | Tuesday, June 28, 2016 |
APPL NO | 15/195596 |
ART UNIT | 1671 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 27/04 (20130101) C07C 29/60 (20130101) C07C 29/132 (20130101) C07C 29/132 (20130101) C07C 29/132 (20130101) C07C 29/132 (20130101) C07C 31/12 (20130101) C07C 31/20 (20130101) C07C 31/125 (20130101) C07C 41/09 (20130101) C07C 45/59 (20130101) C07C 45/60 (20130101) Original (OR) Class C07C 51/377 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/42 (20130101) C10G 3/52 (20130101) C10G 2300/1014 (20130101) C10G 2300/1018 (20130101) C10G 2400/22 (20130101) C10G 2400/30 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) C10L 2200/0469 (20130101) C10L 2270/04 (20130101) C10L 2270/023 (20130101) C10L 2270/026 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657304 | Benning et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Christoph Benning (East Lansing, Michigan); Sanjaya (East Lansing, Michigan) |
ABSTRACT | The invention relates to genetically modified agricultural plants with increased oil content in vegetative tissues, as well as to expression systems, plant cells, seeds and vegetative tissues related thereto. |
FILED | Wednesday, July 10, 2013 |
APPL NO | 13/938784 |
ART UNIT | 1662 — Plants |
CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657400 | Swala et al. |
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FUNDED BY |
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APPLICANT(S) | Dana Ray Swala (Schenectady, New York); Richard Scott Bourgeois (Albany, New York); Steven Paraszczak (Clifton Park, New York); Donald Joseph Buckley (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Dana Ray Swala (Schenectady, New York); Richard Scott Bourgeois (Albany, New York); Steven Paraszczak (Clifton Park, New York); Donald Joseph Buckley (Schenectady, New York) |
ABSTRACT | The present techniques provide a novel electrolyzer and methods for welding components of such electrolyzers. The techniques may use conductors, such as resistance wires, placed in paths around the internal structural features and edges of the components. The conductors may be incorporated into the components during manufacture by injection molding, or other molding techniques, or may be tacked or otherwise applied to the surface of the components after manufacture. When current, a field or other excitation is applied to the conductors, the plastic surrounding the wire is melted. If this plastic is in direct contact with an adjoining component, a strong, hermetic seal may be formed between the two components, including the internal structural features. |
FILED | Tuesday, June 10, 2008 |
APPL NO | 12/136383 |
ART UNIT | 1754 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/342 (20130101) B29C 65/362 (20130101) B29C 65/3476 (20130101) B29C 65/3632 (20130101) B29C 65/3676 (20130101) B29C 66/54 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/543 (20130101) B29C 66/919 (20130101) B29C 66/949 (20130101) B29C 66/5414 (20130101) B29C 66/91411 (20130101) B29C 66/91651 (20130101) B29C 66/91933 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/06 (20130101) B29K 2023/06 (20130101) B29K 2023/12 (20130101) B29K 2023/12 (20130101) B29K 2025/00 (20130101) B29K 2025/06 (20130101) B29K 2025/08 (20130101) B29K 2027/12 (20130101) B29K 2027/12 (20130101) B29K 2063/00 (20130101) B29K 2063/00 (20130101) B29K 2069/00 (20130101) B29K 2069/00 (20130101) B29K 2071/00 (20130101) B29K 2071/00 (20130101) B29K 2071/12 (20130101) B29K 2071/12 (20130101) B29K 2077/00 (20130101) B29K 2077/00 (20130101) B29K 2079/08 (20130101) B29K 2079/08 (20130101) B29K 2079/085 (20130101) B29K 2079/085 (20130101) B29K 2081/04 (20130101) B29K 2081/04 (20130101) B29K 2081/06 (20130101) B29K 2081/06 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/00 (20130101) Original (OR) Class C25B 9/18 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/366 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657966 | Litwin et al. |
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FUNDED BY |
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APPLICANT(S) | Robert Zachary Litwin (Canoga Park, California); David Wait (Canoga Park, California); Robert T. Lancet (Canoga Park, California) |
ASSIGNEE(S) | SOLARRESERVE (Santa Monica, California) |
INVENTOR(S) | Robert Zachary Litwin (Canoga Park, California); David Wait (Canoga Park, California); Robert T. Lancet (Canoga Park, California) |
ABSTRACT | Thermocline storage tanks for solar power systems are disclosed. A thermocline region is provided between hot and cold storage regions of a fluid within the storage tank cavity. One example storage tank includes spaced apart baffles fixed relative to the tank and arranged within the thermocline region to substantially physically separate the cavity into hot and cold storage regions. In another example, a flexible baffle separated the hot and cold storage regions and deflects as the thermocline region shifts to accommodate changing hot and cold volumes. In yet another example, a controller is configured to move a baffle within the thermocline region in response to flow rates from hot and cold pumps, which are used to pump the fluid. |
FILED | Wednesday, December 16, 2009 |
APPL NO | 12/639056 |
ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Producing or Use of Heat Not Otherwise Provided For F24J 2/34 (20130101) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/0039 (20130101) F28D 2020/0047 (20130101) F28D 2020/0091 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 2265/14 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) Y02E 60/142 (20130101) Y02E 70/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658137 | Harvey et al. |
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FUNDED BY |
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APPLICANT(S) | Chris Harvey (French Camp, California); Jerry Carter (Livermore, California); David M. Chambers (Johns Creek, Georgia) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Chris Harvey (French Camp, California); Jerry Carter (Livermore, California); David M. Chambers (Johns Creek, Georgia) |
ABSTRACT | A magnetically-induced SPME fiber actuation system includes a SPME fiber holder and a SPME fiber holder actuator, for holding and magnetically actuating a SPME fiber assembly. The SPME fiber holder has a plunger with a magnetic material to which the SPME fiber assembly is connected, and the magnetic SPME fiber holder actuator has an elongated barrel with a loading chamber for receiving the SPME fiber assembly-connected SPME fiber holder, and an external magnet which induces axial motion of the magnetic material of the plunger to extend/retract the SPME fiber from/into the protective needle of the SPME fiber assembly. |
FILED | Wednesday, June 18, 2014 |
APPL NO | 14/308503 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) Original (OR) Class G01N 1/405 (20130101) G01N 2030/009 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658350 | Stowe et al. |
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FUNDED BY |
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APPLICANT(S) | Ashley C. Stowe (Knoxville, Tennessee); Brenden Wiggins (Oak Ridge, Tennessee); Arnold Burger (Nashville, Tennessee) |
ASSIGNEE(S) | CONSOLIDATED NUCLEAR SECURITY, LLC (Oak Ridge, Tennessee); FISK UNIVERSITY (Nashville, Tennessee) |
INVENTOR(S) | Ashley C. Stowe (Knoxville, Tennessee); Brenden Wiggins (Oak Ridge, Tennessee); Arnold Burger (Nashville, Tennessee) |
ABSTRACT | A radiation detection device, including: a support structure; and a chalcopyrite crystal coupled to the support structure; wherein, when the chalcopyrite crystal is exposed to radiation, a visible spectrum of the chalcopyrite crystal changes from an initial color to a modified color. The visible spectrum of the chalcopyrite crystal is changed back from the modified color to the initial color by annealing the chalcopyrite crystal at an elevated temperature below a melting point of the chalcopyrite crystal over time. The chalcopyrite crystal is optionally a 6LiInSe2 crystal. The radiation is comprised of neutrons that decrease the 6Li concentration of the chalcopyrite crystal via a 6Li(n,α) reaction. The initial color is yellow and the modified color is one of orange and red. The annealing temperature is between about 450 degrees C. and about 650 degrees C. and the annealing time is between about 12 hrs and about 36 hrs. |
FILED | Wednesday, June 03, 2015 |
APPL NO | 14/729715 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 11/12 (20130101) C30B 29/46 (20130101) C30B 33/02 (20130101) Measurement of Nuclear or X-radiation G01T 3/00 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/67098 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658444 | O'Neill |
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FUNDED BY |
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APPLICANT(S) | National Security Technologies, LLC (Las Vegas, Nevada) |
ASSIGNEE(S) | National Security Technologies, LLC (Las Vegas, Nevada) |
INVENTOR(S) | Mary Morabito O'Neill (Santa Barbara, California) |
ABSTRACT | An autofocus system includes an imaging device, a lens system and a focus control actuator that is configured to change a focus position of the imaging device in relation to a stage. The electronic control unit is configured to control the focus control actuator to a plurality of predetermined focus positions, and activate the imaging device to obtain an image at predetermined positions and then apply a spatial filter to the obtained images. This generates a filtered image for the obtained images. The control unit determines a focus score for the filtered images such that the focus score corresponds to a degree of focus in the obtained images. The control unit identifies a best focus position by comparing the focus score of the filtered images, and controls the focus control actuator to the best focus position corresponding to the highest focus score. |
FILED | Wednesday, November 12, 2014 |
APPL NO | 14/539962 |
ART UNIT | 2488 — Recording and Compression |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/23212 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658612 | Spicer et al. |
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FUNDED BY |
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APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
INVENTOR(S) | John Patrick Spicer (Plymouth, Michigan); Wayne W. Cai (Troy, Michigan); Debejyo Chakraborty (Novi, Michigan); Keith Mink (Clarkston, Michigan) |
ABSTRACT | A vibration welding system includes vibration welding equipment having a welding horn and anvil, a host machine, a check station, and a welding robot. At least one displacement sensor is positioned with respect to one of the welding equipment and the check station. The robot moves the horn and anvil via an arm to the check station, when a threshold condition is met, i.e., a predetermined amount of time has elapsed or a predetermined number of welds have been completed. The robot moves the horn and anvil to the check station, activates the at least one displacement sensor, at the check station, and determines a status condition of the welding equipment by processing the received signals. The status condition may be one of the alignment of the vibration welding equipment and the wear or degradation of the vibration welding equipment. |
FILED | Tuesday, December 02, 2014 |
APPL NO | 14/557923 |
ART UNIT | 2127 — AI & Simulation/Modeling |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/10 (20130101) B23K 20/26 (20130101) B23K 31/12 (20130101) B23K 2201/36 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4065 (20130101) Original (OR) Class G05B 2219/45146 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659145 | Sayood et al. |
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FUNDED BY |
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APPLICANT(S) | Khalid Sayood (Lincoln, Nebraska); Sam Way (Boulder, Colorado); Ozkan Ufuk Nalbantoglu (Lincoln, Nebraska); George Garrity (Okemos, Michigan) |
ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska); NamesforLife, LLC (Lansing, Michigan) |
INVENTOR(S) | Khalid Sayood (Lincoln, Nebraska); Sam Way (Boulder, Colorado); Ozkan Ufuk Nalbantoglu (Lincoln, Nebraska); George Garrity (Okemos, Michigan) |
ABSTRACT | DNA sequences are analyzed using latent semantic analysis. A set of nucleotide sequences is received in which the set has a first number of sequences. A set of basis vectors is determined, in which the set has a second number of basis vectors, the second number being smaller than the first number. Each basis vector represents a specific combination of predetermined nucleotide segments. For each of the nucleotide sequences, an approximate representation of the nucleotide sequence is determined based on a combination of the basis vectors. For each pair of nucleotide sequences, a distance between the pair of nucleotide sequences is determined according the distance between the approximate representation of the pair of nucleotide sequences. The set of nucleotide sequences are classified based on the distances between the pairs of nucleotide sequences. |
FILED | Tuesday, July 30, 2013 |
APPL NO | 13/954925 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Electric Digital Data Processing G06F 19/22 (20130101) Original (OR) Class G06F 19/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659205 | Demos |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Stavros Demos (Livermore, California) |
ABSTRACT | Systems and methods are disclosed for obtaining at least a pair of biometric traits of a person and without contact with the person. In one embodiment a system is disclosed which makes use of a plurality of illumination modules and an imaging module, where a single image is acquired with a color encoded imaging sensor. Parallel and orthogonally polarized images are obtained by at least one sensor of the imaging module from illuminations produced by the illumination modules. A processing subsystem uses mathematical applied operations between the acquired images to selectively produce at least one image of at least one specific biometric trait, such as a finger print, a palm print, a finger-vein, a palm vein, or hand geometry. The biometric trait can be subsequently used for biometric verification and identification. |
FILED | Monday, June 09, 2014 |
APPL NO | 14/299867 |
ART UNIT | 2488 — Recording and Compression |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00013 (20130101) Original (OR) Class G06K 9/00885 (20130101) G06K 9/00892 (20130101) G06K 9/2018 (20130101) G06K 2009/00932 (20130101) Pictorial Communication, e.g Television H04N 5/2354 (20130101) H04N 7/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659706 | Qiu et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
INVENTOR(S) | Jizheng Qiu (West Lebanon, New Hampshire); Charles R. Sullivan (West Lebanon, New Hampshire) |
ABSTRACT | A method of forming a radially anisotropic toroidal magnetic core includes providing apparatus having a first magnet for providing a radial magnetic field extending across a cavity from an axial spindle to a surrounding second magnetic element, placing a substrate in the cavity, the substrate having a hole fitting around the head of the spindle; and sputter-depositing a film of ferromagnetic material onto the substrate. In an embodiment, the spindle is magnetically coupled to a first pole of the first magnet, the second magnetic element is coupled to a second pole of the first magnet, and a thermally conductive, nonmagnetic, insert separates the spindle and the second magnetic element. |
FILED | Monday, September 24, 2012 |
APPL NO | 14/346659 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/458 (20130101) C23C 16/4583 (20130101) C23C 16/4584 (20130101) Static Stores G11C 19/08 (20130101) G11C 19/0808 (20130101) G11C 19/0816 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 3/02 (20130101) H01F 7/02 (20130101) H01F 7/0273 (20130101) H01F 41/02 (20130101) Original (OR) Class H01F 41/18 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49075 (20150115) Y10T 29/49076 (20150115) Y10T 29/49078 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659797 | Burckel et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | David Bruce Burckel (Albuquerque, New Mexico); Robert L. Jarecki, Jr. (Albuquerque, New Mexico); Patrick Sean Finnegan (Albuquerque, New Mexico) |
ABSTRACT | Wafer scale oblique angle etching of a semiconductor substrate is performed in a conventional plasma etch chamber by using a fixture that supports a multiple number of separate Faraday cages. Each cage is formed to include an angled grid surface and is positioned such that it will be positioned over a separate one of the die locations on the wafer surface when the fixture is placed over the wafer. The presence of the Faraday cages influences the local electric field surrounding each wafer die, re-shaping the local field to be disposed in alignment with the angled grid surface. The re-shaped plasma causes the reactive ions to follow a linear trajectory through the plasma sheath and angled grid surface, ultimately impinging the wafer surface at an angle. The selected geometry of the Faraday cage angled grid surface thus determines the angle at with the reactive ions will impinge the wafer. |
FILED | Wednesday, September 17, 2014 |
APPL NO | 14/489362 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) H01L 21/3085 (20130101) H01L 21/67069 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660026 | Okandan et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Murat Okandan (Edgewood, New Mexico); Bruce L. Draper (Albuquerque, New Mexico); Paul J. Resnick (Albuquerque, New Mexico) |
ABSTRACT | There is provided an electronic device and a method for its manufacture. The device comprises an elongate silicon nanowire less than 0.5 μm in cross-sectional dimensions and having a hexagonal cross-sectional shape due to annealing-induced energy relaxation. The method, in examples, includes thinning the nanowire through iterative oxidation and etching of the oxidized portion. |
FILED | Thursday, November 17, 2016 |
APPL NO | 15/354196 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0675 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/306 (20130101) H01L 21/3065 (20130101) H01L 29/0669 (20130101) Original (OR) Class H01L 29/0673 (20130101) H01L 29/0847 (20130101) H01L 29/1037 (20130101) H01L 29/7853 (20130101) H01L 29/42376 (20130101) H01L 29/42392 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660125 | Plesniak et al. |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Adam P. Plesniak (Huntington Beach, California); John C. Hall (Rancho Palos Verdes, California) |
ABSTRACT | A method of making a solar concentrator may include forming a receiving wall having an elongated wall, a first side wall and a second side wall; attaching the first side wall and the second side wall to a reflecting wall to form a housing having an internal volume with an opening; forming a lip on the receiving wall and the reflecting wall; attaching a cover to the receiving wall and the reflecting wall at the lip to seal the opening into the internal volume, thereby creating a rigid structure; and mounting at least one receiver having at least one photovoltaic cell on the elongated wall to receive solar radiation entering the housing and reflected by the receiving wall, the receiver having an axis parallel with a surface normal of the photovoltaic cell, such that the axis is disposed at a non-zero angle relative to the vertical axis of the opening. |
FILED | Tuesday, January 27, 2015 |
APPL NO | 14/606316 |
ART UNIT | 1757 — Semiconductors/Memory |
CURRENT CPC | Producing or Use of Heat Not Otherwise Provided For F24J 2/06 (20130101) F24J 2/08 (20130101) F24J 2/08 (20130101) F24J 2/10 (20130101) F24J 2/12 (20130101) F24J 2/14 (20130101) F24J 2/50 (20130101) F24J 2/464 (20130101) F24J 2/1057 (20130101) F24J 2/5243 (20130101) F24J 2002/1085 (20130101) F24J 2002/4692 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/052 (20130101) H01L 31/052 (20130101) H01L 31/054 (20141201) H01L 31/0547 (20141201) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) Y02E 10/45 (20130101) Y02E 10/52 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49355 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660241 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Sharp Laboratories of America, Inc. (Camas, Washington) |
ASSIGNEE(S) | Sharp Laboratories of America, Inc. (Camas, Washington) |
INVENTOR(S) | Long Wang (Vancouver, Washington); Yuhao Lu (Vancouver, Washington); Jong-Jan Lee (Camas, Washington); Sean Vail (Vancouver, Washington) |
ABSTRACT | A method is provided for forming a sodium-containing particle electrolyte structure. The method provides sodium-containing particles (e.g., NASICON), dispersed in a liquid phase polymer, to form a polymer film with sodium-containing particles distributed in the polymer film. The liquid phase polymer is a result of dissolving the polymer in a solvent or melting the polymer in an extrusion process. In one aspect, the method forms a plurality of polymer film layers, where each polymer film layer includes sodium-containing particles. For example, the plurality of polymer film layers may form a stack having a top layer and a bottom layer, where with percentage of sodium-containing particles in the polymer film layers increasing from the bottom layer to the top layer. In another aspect, the sodium-containing particles are coated with a dopant. A sodium-containing particle electrolyte structure and a battery made using the sodium-containing particle electrolyte structure are also presented. |
FILED | Thursday, March 06, 2014 |
APPL NO | 14/198755 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 17/02 (20130101) C01B 19/02 (20130101) C01B 25/003 (20130101) C01B 31/00 (20130101) C01B 33/021 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 3/12 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 1/02 (20130101) C01D 15/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/14 (20130101) H01M 2/1653 (20130101) H01M 2/1686 (20130101) Original (OR) Class H01M 4/04 (20130101) H01M 4/38 (20130101) H01M 4/049 (20130101) H01M 4/56 (20130101) H01M 4/58 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/136 (20130101) H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 4/387 (20130101) H01M 4/0404 (20130101) H01M 4/0416 (20130101) H01M 4/0452 (20130101) H01M 4/0471 (20130101) H01M 4/485 (20130101) H01M 4/0495 (20130101) H01M 4/0497 (20130101) H01M 4/505 (20130101) H01M 4/587 (20130101) H01M 4/628 (20130101) H01M 4/1391 (20130101) H01M 4/1395 (20130101) H01M 4/1397 (20130101) H01M 4/5825 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0042 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49108 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660265 | Visco et al. |
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FUNDED BY |
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APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
ASSIGNEE(S) | POLYPLUS BATTERY COMPANY (Berkeley, California) |
INVENTOR(S) | Steven J. Visco (Berkeley, California); Nikolay Goncharenko (Walnut Creek, California); Vitaliy Nimon (San Francisco, California); Alexei Petrov (Walnut Creek, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California); Bruce D. Katz (Moraga, California); Valentina Loginova (Walnut Creek, California) |
ABSTRACT | Lithium sulfur battery cells that use water as an electrolyte solvent provide significant cost reductions. Electrolytes for the battery cells may include water solvent for maintaining electroactive sulfur species in solution during cell discharge and a sufficient amount of a cycle life-enhancing compound that facilitates charging at the cathode. The combination of these two components enhances one or more of the following cell attributes: energy density, power density and cycle life. For instance, in applications where cost per Watt-Hour (Wh) is paramount, such as grid storage and traction applications, the use of an aqueous electrolyte in combination with inexpensive sulfur as the cathode active material can be a key enabler for the utility and automotive industries, for example, providing a cost effective and compact solution for load leveling, electric vehicles and renewable energy storage. Sulfur cathodes, and methods of fabricating lithium sulfur cells, in particular for loading lithium sulfide into the cathode structures, provide further advantages. |
FILED | Friday, March 13, 2015 |
APPL NO | 14/657695 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/40 (20130101) H01M 4/38 (20130101) H01M 4/74 (20130101) H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/405 (20130101) H01M 4/485 (20130101) H01M 4/587 (20130101) H01M 4/661 (20130101) H01M 4/663 (20130101) H01M 4/667 (20130101) H01M 4/806 (20130101) H01M 4/808 (20130101) H01M 4/5815 (20130101) Original (OR) Class H01M 10/36 (20130101) H01M 2300/0002 (20130101) H01M 2300/0014 (20130101) H01M 2300/0037 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660268 | Song et al. |
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FUNDED BY |
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APPLICANT(S) | Sharp Laboratories of America, Inc. (Camas, Washington) |
ASSIGNEE(S) | Sharp Laboratories of America, Inc. (Camas, Washington) |
INVENTOR(S) | Jie Song (Vancouver, Washington); Yuhao Lu (Camas, Washington); Xin Zhao (Vancouver, Washington) |
ABSTRACT | An alkali-ion battery is provided with a transition metal cyanometallate (TMCM) sheet cathode and a non-alkaline metal anode. The fabrication method mixes TMCM powders, conductive additives, and a polytetrafluoroethylene binder with a solution containing water, forming a wet paste. The wet paste is formed into a free-standing sheet of cathode active material, which is laminated to a cathode current collector, forming a cathode electrode. The free-standing sheet of cathode active material has a thickness typically in the range of 100 microns to 2 millimeters. The cathode electrode is assembled with a non-alkaline metal anode electrode and an ion-permeable membrane interposed between the cathode electrode and anode electrode, forming an assembly. The assembly is dried at a temperature of greater than 100 degrees C. The dried assembly is then inserted into a container (case) and electrolyte is added. Thick anodes made from free-standing sheets of active material can be similarly formed. |
FILED | Friday, October 30, 2015 |
APPL NO | 14/928559 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Ammonia; Cyanogen; Compounds Thereof C01C 3/11 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/162 (20130101) H01M 2/1626 (20130101) H01M 2/1646 (20130101) H01M 4/56 (20130101) H01M 4/136 (20130101) H01M 4/381 (20130101) H01M 4/387 (20130101) H01M 4/622 (20130101) H01M 4/623 (20130101) H01M 4/1397 (20130101) H01M 4/5825 (20130101) Original (OR) Class H01M 10/054 (20130101) H01M 10/0585 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660299 | Xu et al. |
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FUNDED BY |
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APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
INVENTOR(S) | Jeff Qiang Xu (San Antonio, Texas); Joe Steiber (Spring Branch, Texas); Craig M. Wall (San Antonio, Texas); Robert Smith (Fair Lawn, New Jersey); Cheuk Ng (San Antonio, Texas) |
ABSTRACT | A method and system for strain-based estimation of the state of health of a battery, from an initial state to an aged state, is provided. A strain gauge is applied to the battery. A first strain measurement is performed on the battery, using the strain gauge, at a selected charge capacity of the battery and at the initial state of the battery. A second strain measurement is performed on the battery, using the strain gauge, at the selected charge capacity of the battery and at the aged state of the battery. The capacity degradation of the battery is estimated as the difference between the first and second strain measurements divided by the first strain measurement. |
FILED | Tuesday, December 10, 2013 |
APPL NO | 14/102197 |
ART UNIT | 2859 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3679 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/42 (20130101) Original (OR) Class H01M 10/48 (20130101) H01M 10/4285 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660311 | Visco et al. |
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FUNDED BY |
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APPLICANT(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California); Alexei Petrov (Walnut Creek, California); Nikolay Goncharenko (Walnut Creek, California) |
ASSIGNEE(S) | POLYPLUS BATTERY COMPANY (Berkeley, California) |
INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California); Alexei Petrov (Walnut Creek, California); Nikolay Goncharenko (Walnut Creek, California) |
ABSTRACT | Aqueous Li/Air secondary battery cells are configurable to achieve high energy density and prolonged cycle life. The cells include a protected a lithium metal or alloy anode and an aqueous catholyte in a cathode compartment. The aqueous catholyte comprises an evaporative-loss resistant and/or polyprotic active compound or active agent that partakes in the discharge reaction and effectuates cathode capacity for discharge in the acidic region. This leads to improved performance including one or more of increased specific energy, improved stability on open circuit, and prolonged cycle life, as well as various methods, including a method of operating an aqueous Li/Air cell to simultaneously achieve improved energy density and prolonged cycle life. |
FILED | Friday, August 17, 2012 |
APPL NO | 13/588911 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 12/08 (20130101) Original (OR) Class H01M 2300/0005 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/128 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660520 | Perreault et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | David J. Perreault (Andover, Massachusetts); Seungbum Lim (Cambridge, Massachusetts); David M. Otten (Newton, Massachusetts) |
ABSTRACT | A power converter circuit rectifies a line voltage and applies the rectified voltage to a stack of capacitors. Voltages on the capacitors are coupled to a plurality of regulating converters to be converted to regulated output signals. The regulated output signals are combined and converted to a desired DC output voltage of the power converter. Input currents of the regulating converters are modulated in a manner that enhances the power factor of the power converter. |
FILED | Tuesday, April 08, 2014 |
APPL NO | 14/758033 |
ART UNIT | 2838 — Electrical Circuits and Systems |
CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/4208 (20130101) H02M 1/4225 (20130101) H02M 1/4241 (20130101) Original (OR) Class H02M 3/158 (20130101) H02M 3/33569 (20130101) H02M 7/06 (20130101) H02M 2001/007 (20130101) H02M 2001/0074 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 70/126 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09661733 | Elizondo-Decanini |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Juan M. Elizondo-Decanini (Albuquerque, New Mexico) |
ABSTRACT | Switching devices are provided. The switching devices include an input electrode, having a main electrode and a trigger electrode, and an output electrode. The main electrode and the trigger electrode are separated from the output electrode by a main gap and a trigger gap, respectively. During operation, the trigger electrode compresses and amplifies a trigger voltage signal causing the trigger electrode to emit a pulse of energy. This pulse of energy form plasma near the trigger electrode, either by arcing across the trigger gap, or by arcing from the trigger electrode to the main electrode. This plasma decreases the breakdown voltage of the main gap. Simultaneously, or near simultaneously, a main voltage signal propagates through the main electrode. The main voltage signal emits a main pulse of energy that arcs across the main gap while the plasma formed by the trigger pulse is still present. |
FILED | Friday, September 30, 2016 |
APPL NO | 15/281991 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/48 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09661737 | Trbojevic |
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FUNDED BY |
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APPLICANT(S) | Dejan Trbojevic (Wading River, New York) |
ASSIGNEE(S) | The United States of America, as represented by the Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Dejan Trbojevic (Wading River, New York) |
ABSTRACT | A non-scaling fixed field alternating gradient accelerator includes a racetrack shape including a first straight section connected to a first arc section, the first arc section connected to a second straight section, the second straight section connected to a second arc section, and the second arc section connected to the first straight section; an matching cells configured to match particle orbits between the first straight section, the first arc section, the second straight section, and the second arc section. The accelerator includes the matching cells and an associated matching procedure enabling the particle orbits at varying energies between an arc section and a straight section in the racetrack shape. |
FILED | Friday, May 23, 2014 |
APPL NO | 14/285706 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 13/08 (20130101) H05H 13/085 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 09655553 | Plumley et al. |
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FUNDED BY |
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APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | John B. Plumley (Albuquerque, New Mexico); Erin D. Milligan (Placitas, New Mexico); Marek Osinski (Albuquerque, New Mexico) |
ABSTRACT | The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided. |
FILED | Thursday, September 10, 2015 |
APPL NO | 14/850221 |
ART UNIT | 3777 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1455 (20130101) Original (OR) Class A61B 5/1459 (20130101) A61B 5/4058 (20130101) A61B 5/6852 (20130101) A61B 5/6877 (20130101) A61B 5/14735 (20130101) A61B 2562/0233 (20130101) A61B 2562/0285 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09655679 | Desai et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MARYLAND, OFFICE OF TECHNOLOGY COMMERCIALIZATION (College Park, Maryland) |
ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
INVENTOR(S) | Jaydev P. Desai (Bethesda, Maryland); Elif Ayvali (College Park, Maryland) |
ABSTRACT | A steerable probe having high-power-density actuators positioned at joints along the length of the probe. The actuators are moveable about and between a straight position and a curved position in response to selective actuation. |
FILED | Wednesday, May 01, 2013 |
APPL NO | 13/875204 |
ART UNIT | 3779 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3417 (20130101) A61B 17/3421 (20130101) A61B 19/201 (20130101) Original (OR) Class A61B 90/11 (20160201) A61B 90/39 (20160201) A61B 2017/003 (20130101) A61B 2017/00867 (20130101) A61B 2034/2055 (20160201) A61B 2090/3735 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656001 | Mayes et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Sarah Mayes (Austin, Texas); Christine E. Schmidt (Gainesville, Florida) |
ABSTRACT | A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components. |
FILED | Monday, July 20, 2015 |
APPL NO | 14/803258 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/195 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) A61L 31/041 (20130101) Original (OR) Class A61L 31/041 (20130101) A61L 31/041 (20130101) A61L 31/145 (20130101) A61L 31/148 (20130101) A61L 2300/43 (20130101) A61L 2300/62 (20130101) A61L 2300/414 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656262 | Paliwal et al. |
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FUNDED BY |
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APPLICANT(S) | Saurabh Paliwal (Mountain View, California); Zhizhong Yin (Timonium, Maryland); Raymond Cheong (Timonium, Maryland) |
ASSIGNEE(S) | EUVEDA BIOSCIENCES, INC. (Timonium, Maryland) |
INVENTOR(S) | Saurabh Paliwal (Mountain View, California); Zhizhong Yin (Timonium, Maryland); Raymond Cheong (Timonium, Maryland) |
ABSTRACT | Microfluidic devices have been developed to perform a range of high-throughput biochemical and cell-based assays over recent years. A design for a microfluidic device has been developed that resembles a microtiter plate, by placing the test chambers (each test chamber contains cells) and top-loading drug inlets (at least one per test chamber) in a grid according to the ANSI/SBS standards, yet offers the miniaturization and fluid handling advantages of microfluidics. This ensures that the device design is compatible with fluid handling and imaging equipment already in use for drug screening. A range of topologies have been determined that allow placement of various elements of this microfluidic network within the grid alignment constraints. A resistance equalization methodology has also been developed to reduce variability across assays run in different chambers of the microfluidic device. Additionally, it offers orders of magnitude miniaturization over multiwell plates, and potentially more reliable fluid handling. |
FILED | Tuesday, June 10, 2014 |
APPL NO | 14/301319 |
ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 2300/0829 (20130101) B01L 2300/0864 (20130101) B01L 2300/0874 (20130101) B01L 2300/0883 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656414 | Fourkas et al. |
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FUNDED BY |
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APPLICANT(S) | John T. Fourkas (Bethesda, Maryland); Christopher N. LaFratta (Brighton, Massachusetts) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | John T. Fourkas (Bethesda, Maryland); Christopher N. LaFratta (Brighton, Massachusetts) |
ABSTRACT | The present invention relates to microfluidic devices that comprise a 3-D microfluidic network of microchannels of arbitrary complexity and to a method for fabricating such devices. In particular, the invention relates to a method of forming microfluidic devices having 3-D microfluidic networks that contain open or closed loop microchannels using a single-step molding process without the need for layer-by-layer fabrication, and to the resultant microfluidic devices. The networks of such microfluidic devices may comprise one or more microchannel circuits which may be discrete or interconnected. |
FILED | Monday, February 24, 2014 |
APPL NO | 14/187673 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/405 (20130101) B29C 33/3857 (20130101) B29C 39/006 (20130101) B29C 39/36 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/756 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/2224 (20150401) Y10T 137/8593 (20150401) Y10T 137/85938 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656900 | Jain et al. |
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FUNDED BY |
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APPLICANT(S) | Himanshu Jain (Bethlehem, Pennsylvania); Hassan Mohamady Mohamed Moawad (Bethlehem, Pennsylvania) |
ASSIGNEE(S) | Lehigh University (Bethlehem, Pennsylvania) |
INVENTOR(S) | Himanshu Jain (Bethlehem, Pennsylvania); Hassan Mohamady Mohamed Moawad (Bethlehem, Pennsylvania) |
ABSTRACT | Provided herein are methods for preparing nano-macroporous glass articles, such as bioscaffolds, from starting materials such as phosphosilicate glasses made by melt-quench methods, mixed with a soluble pore former such as a sugar, followed by steps of dissolving, heating, and leaching to yield a glass composition having a highly interconnected system of both macropores and large scale nanoporosity. |
FILED | Thursday, January 26, 2012 |
APPL NO | 13/358858 |
ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 19/06 (20130101) C03B 32/02 (20130101) Original (OR) Class Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 11/005 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/268 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658162 | Wickramasinghe |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | H. Kumar Wickramasinghe (Irvine, California) |
ABSTRACT | An apparatus and method for measuring amplitude and/or phase of a molecular vibration uses a polarization modulated pump beam and a stimulating Stokes beam on a probe of a scanning probe microscope to detect a Raman scattered Stokes beam from the sample. The detected Raman scattered Stokes beam is used to derive at least one of the amplitude and the phase of the molecular vibration. |
FILED | Monday, March 09, 2015 |
APPL NO | 14/642655 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) G01J 3/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2021/655 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658206 | Siwy et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Zuzanna S. Siwy (Irvine, California); Kenneth J. Shea (Irvine, California); Ken Healy (Auburn, Alabama); Laura Michele Innes (Cerritos, California); Matthew Schiel (Irvine, California); Matthew Pevarnik (Irvine, California) |
ABSTRACT | A method for multiplex characterization of individual particles by their size, shape, mechanical properties (deformability), and chemical affinity to recognition agents. The analysis can be performed from concentrated solutions. The method detects transient sticking of particles in the pore and points to its location along a pore axis. If a pore is decorated with a recognition agent for an analyte present in a solution, it is possible to distinguish specific binding at the place of the recognition agent, and non-specific adsorption of the analyte. The method confirms whether any individual particle or hydrogel completely translocates the pore and allows unambiguous detection and characterization of multiple particles or hydrogels in the pore, which would previously corrupt the results, so that higher analyte concentrations can be used for faster analysis. High aspect ratio of the pores (ratio of pore length and diameter) together with the pattern of ion current pulses also allow passage of the same particle or cell multiple times without letting the cell exit the pore. |
FILED | Friday, May 09, 2014 |
APPL NO | 14/274404 |
ART UNIT | 1759 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1218 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658443 | Broxton et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Michael J. Broxton (San Francisco, California); Marc S. Levoy (Stanford, California); Noy Cohen (Stanford, California); Logan Grosenick (San Francisco, California); Samuel Yang (Stanford, California); Karl A. Deisseroth (Stanford, California) |
ABSTRACT | Images are detected in a manner that addresses various challenges as discussed herein. As may be consistent with one or more embodiments, aspects are directed to an apparatus having sets of photosensors that detect light rays received at different angles from a specimen via a microlens array, with the light rays detected by each set of photosensors representing an aliased view of the specimen. An output indicative of aliased views of the specimen is provided. Certain embodiments further include a logic circuit that processes the output and generates a deconvolved volume image by combining aliased views of the specimen as detected by the photosensors. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/209777 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0006 (20130101) G02B 21/367 (20130101) Original (OR) Class G02B 27/0075 (20130101) Pictorial Communication, e.g Television H04N 5/225 (20130101) H04N 13/0232 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658510 | Kippelen et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Bernard Kippelen (Atlanta, Georgia); Canek Fuentes-Hernandez (Atlanta, Georgia); James June Fan Hsu (Atlanta, Georgia) |
ABSTRACT | An optical device capable of an ultrafast and large change of its reflection or absorption coefficient upon being excited by an ultrafast optical pulse with wavelength in the visible, near-infrared, or infrared spectral regions. The optical device includes, in sequential order, a first thick metallic layer, a first dielectric layer, a second thin metallic layer, and a second dielectric layer. The optical device acts as a nonlinear mirror that presents a large reflectance at low irradiance and a low reflectance at large irradiance. The optical device can further act as a nonlinear mirror that presents a linear and nonlinear reflectance with a large angular bandwidth. |
FILED | Friday, December 20, 2013 |
APPL NO | 14/764100 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/17 (20130101) G02F 1/19 (20130101) G02F 1/21 (20130101) Original (OR) Class G02F 1/0126 (20130101) G02F 1/355 (20130101) G02F 1/3523 (20130101) G02F 2001/211 (20130101) G02F 2203/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659189 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Wenke Lee (Atlanta, Georgia); Alexandra Boldyreva (Atlanta, Georgia); Chung Pak Ho (Atlanta, Georgia); Billy Lau (Atlanta, Georgia); Chengyu Song (Atlanta, Georgia) |
ABSTRACT | The disclosed technology includes techniques for improving data privacy in mobile communications over public cloud services. According to certain implementations, a novel conceptual layer may be interposed between the “application” layer and the “user” layer. In some implementations, the conceptual layer may be at least partially embodied by a transparent window or pane overlaid on top of existing app graphical user interfaces to: (1) intercept plaintext user input before transforming the input and feeding it to an underlying app; and (2) reverse transform output data from the app before displaying the plaintext data to the user. Accordingly, the conceptual layer may serve as a protective layer while preserving the original application workflow and look-and-feel. |
FILED | Tuesday, October 14, 2014 |
APPL NO | 14/513680 |
ART UNIT | 2492 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/6263 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0435 (20130101) Wireless Communication Networks H04W 12/00 (20130101) H04W 12/02 (20130101) H04W 88/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659210 | De la Torre et al. |
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FUNDED BY |
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APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Fernando De la Torre (Pittsburgh, Pennsylvania); Xuehan Xiong (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to a system for detecting and tracking facial features in images and can be used in conjunction with a camera. Given a camera, the system will detect facial landmarks in images. The present invention includes software for real time, accurate facial feature detection and tracking in unconstrained images and videos. The present invention is better, more robust and faster than existing approaches and can be implemented very efficiently allowing real-time processing, even on low-power devices, such as mobile phones. |
FILED | Tuesday, January 13, 2015 |
APPL NO | 14/596148 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00241 (20130101) Original (OR) Class G06K 9/00268 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 2207/10004 (20130101) G06T 2207/20081 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659351 | Aliaga et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
INVENTOR(S) | Daniel Gerardo Aliaga (West Lafayette, Indiana); Carlos Roberto Montalto Cruz (Seattle, Washington); Ignacio Garcia Dorado (West Lafayette, Indiana) |
ABSTRACT | A method to generate an output image that improves observation of a target image viewed on a medium by an optical system is disclosed. The method includes receiving at least one target image by a processing system, receiving at least one parameter by the processing system, defining an error signal associated with the difference between calculated optical system observation of intermediate images and the at least one target image, minimizing the error signal, and generating an output image associated with the intermediate image having the minimized error. |
FILED | Thursday, March 12, 2015 |
APPL NO | 14/656681 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/00 (20130101) A61B 3/032 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) Original (OR) Class G06T 5/003 (20130101) G06T 2207/20056 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659372 | Nguyen et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Truong Nguyen (San Diego, California); Ho Chan (La Jolla, California); Ramsin Khoshabeh (San Diego, California) |
ABSTRACT | A method for disparity estimation of stereo video data receives a sequence of frames of stereo video data. Image-based disparity estimation is initially conducted on a frame-by-frame basis to produce initial disparity estimates. A plurality of initial disparity estimates is grouped into a space-time volume. Disparity error is reduced in the space-time volume to refine the initial disparity estimates. |
FILED | Tuesday, May 14, 2013 |
APPL NO | 14/389873 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0022 (20130101) Original (OR) Class G06T 2207/10021 (20130101) Pictorial Communication, e.g Television H04N 13/025 (20130101) H04N 13/0048 (20130101) H04N 13/0488 (20130101) H04N 2013/0081 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660168 | Hall et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Matthew J. Hall (Austin, Texas); Li Shi (Austin, Texas) |
ABSTRACT | A thermoelectric power generator for converting thermal energy into electrical energy. The thermoelectric power generator includes a heat exchanger configured to extract thermal energy from an exhaust gas stream. The heat exchanger includes fins in contact with a boundary of the heat exchanger, where the fins are directly connected to a first set of thermoelectric modules. A second set of thermoelectric modules are directly connected to the boundary of the heat exchanger. The first and second sets of thermoelectric modules are configured to convert the thermal energy to electrical energy. By eliminating the metal wall that previously existed between the thermoelectric modules and the fins, the thermoelectric power generator improves the heat transfer between the exhaust gas and the thermoelectric modules, eliminates the thermal fatigue failures at the bond between the metal wall and the thermoelectric modules as well as allows for a higher density of thermoelectric modules. |
FILED | Thursday, October 02, 2014 |
APPL NO | 14/505068 |
ART UNIT | 1757 — Semiconductors/Memory |
CURRENT CPC | Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 5/025 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/30 (20130101) H01L 35/32 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660416 | Kumar et al. |
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FUNDED BY |
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APPLICANT(S) | LEHIGH UNIVERSITY (Bethlehem, Pennsylvania) |
ASSIGNEE(S) | Lehigh University (Bethlehem, Pennsylvania) |
INVENTOR(S) | Sushil Kumar (Center Valley, Pennsylvania); Chongzhao Wu (Bethlehem, Pennsylvania) |
ABSTRACT | A distributed antenna-coupling feedback scheme and specially designed distributed feedback (DFB) metallic cavity and grating for laser application and in particular to plasmonic lasers ensuring a predesigned phase condition such that a mode traveling inside a waveguide is coupled/phase-locked to a mode traveling on the top metal improving the beam quality of the laser. |
FILED | Wednesday, December 30, 2015 |
APPL NO | 14/984652 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/12 (20130101) Original (OR) Class H01S 5/1046 (20130101) H01S 5/3402 (20130101) H01S 2302/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660995 | Reiter et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
INVENTOR(S) | Michael Kendrick Reiter (Chapel Hill, North Carolina); Apu Chandrasen Kapadia (Bloomington, Indiana); Alana Libonati (Carrboro, North Carolina) |
ABSTRACT | The subject matter described herein includes methods, systems, and computer readable media for combating mobile device theft with user notarization. One method includes providing a supplicant video notarization system application executable on a supplicant device for initiating an interactive video call between a supplicant and a notary as a condition to the supplicant accessing a protected electronic resource. The method further includes providing a notary video notarization system application executable on a notary device through which the notary receives the interactive video call and interacts with the supplicant via the interactive video call to confirm the identity of the supplicant and that video of the supplicant provided in the call is live. |
FILED | Thursday, February 20, 2014 |
APPL NO | 14/769160 |
ART UNIT | 2438 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) G06F 21/88 (20130101) G06F 21/6245 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/10 (20130101) Original (OR) Class H04L 63/0428 (20130101) Pictorial Communication, e.g Television H04N 7/141 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09661051 | Panwar |
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FUNDED BY |
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APPLICANT(S) | Shivendra Panwar (Freehold, New Jersey) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Shivendra Panwar (Freehold, New Jersey) |
ABSTRACT | Video streaming applications are a major contributor to the recent dramatic rise of data traffic in cellular networks. Mobile users in a cellular network often experience fluctuating data rates, which might affect the quality of video they view in a streaming service. Although replacing such video streaming services with video downloading/renting services could potentially allow such mobile users to enjoy consistently higher quality videos, such services typically cost a lot more than video streaming services because of legal copyright pricing and management issues. By downloading enhancement layers but streaming base layers of the content, mobile users can enjoy download-quality videos with a service (legally) classified as a streaming service. |
FILED | Monday, September 28, 2015 |
APPL NO | 14/867503 |
ART UNIT | 2458 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 65/80 (20130101) H04L 65/604 (20130101) H04L 65/607 (20130101) Original (OR) Class H04L 65/4084 (20130101) H04L 67/02 (20130101) H04L 67/42 (20130101) H04L 67/2842 (20130101) H04L 69/02 (20130101) Wireless Communication Networks H04W 84/042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 09655525 | Lee |
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FUNDED BY |
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APPLICANT(S) | Salutron, Inc. (Fremont, California) |
ASSIGNEE(S) | SALUTRON INC. (Newark, California) |
INVENTOR(S) | Yong Jin Lee (Seoul, South Korea) |
ABSTRACT | Described herein are user-wearable devices that include an optical sensor, and methods for use therewith. In certain embodiments, an optical sensor of a user-wearable device (e.g., a wrist-worn device) is used to detect blue light that is incident on the optical sensor and to produce a blue light detection signal indicative thereof, and thus, indicative of the response of the user's intrinsically photosensitive Retinal Ganglion Cells (ipRGCs). In dependence on the blue light detection signal, there is a determination of a metric indicative of an amount of blue light detected by the optical sensor. The metric is compared to a corresponding threshold, and a user notification is triggered in dependence on results of the comparing, wherein the user notification informs a person wearing the user-wearable device to adjust their exposure to light. |
FILED | Wednesday, March 18, 2015 |
APPL NO | 14/661856 |
ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) Original (OR) Class A61B 5/0205 (20130101) A61B 5/681 (20130101) A61B 5/1118 (20130101) A61B 5/02416 (20130101) A61B 5/4857 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09656426 | Snyder et al. |
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FUNDED BY |
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APPLICANT(S) | MADE IN SPACE, INC. (Moffett Field, California) |
ASSIGNEE(S) | MADE IN SPACE, INC. (Moffett Field, California) |
INVENTOR(S) | Michael Snyder (Mountain View, California); Jason Dunn (Mountain View, California); Michael Chen (Mountain View, California); Aaron Kemmer (Mountain View, California); Noah Paul-Gin (San Fransisco, California); Matthew Napoli (Sunnyvale, California); Eddie Gonzalez (San Fransisco, California); Michael Pless (Lodi, California) |
ABSTRACT | Additive manufacturing devices operable in various external force environments are disclosed. In an aspect, an additive manufacturing device operable in microgravity is disclosed. In other aspects, devices which are operable in high-vibration environments or varying external force environments are disclosed. Additive manufacturing devices herein may produce parts from metal, polymer, or other feedstocks. |
FILED | Monday, December 14, 2015 |
APPL NO | 14/968112 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Separation B01D 45/14 (20130101) B01D 46/0032 (20130101) B01D 46/46 (20130101) B01D 46/442 (20130101) B01D 46/444 (20130101) B01D 46/448 (20130101) B01D 50/002 (20130101) Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 11/01 (20130101) B22D 11/10 (20130101) B22D 11/16 (20130101) B22D 23/00 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/0055 (20130101) B29C 67/0059 (20130101) B29C 67/0074 (20130101) B29C 67/0081 (20130101) B29C 67/0085 (20130101) Original (OR) Class B29C 67/0088 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 50/02 (20141201) B33Y 99/00 (20141201) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657251 | Richmond et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Robert Chaffee Richmond (Madison, Alabama); Harry F. Schramm, Jr. (Winchester, Tennessee); Francis G. Defalco (Houston, Texas) |
ABSTRACT | A wear and/or friction reducing additive for a lubricating fluid in which the additive is a combination of a moderately hydrophilic single-phase compound and an anti-wear and/or anti-friction aqueous salt solution. The aqueous salt solution produces a coating on boundary layer surfaces. The lubricating fluid can be an emulsion-free hydrophobic oil, hydraulic fluid, antifreeze, water, or a water-based lubricant. Preferably, the moderately hydrophilic single-phase compound is sulfonated castor oil and the aqueous salt solution additionally contains boric acid and zinc oxide. The emulsions produced by the aqueous salt solutions, the moderately hydrophilic single-phase compounds, or the combination thereof provide targeted boundary layer organizers that significantly enhance the anti-wear and/or anti-friction properties of the base lubricant by decreasing wear and/or friction of sliding and/or rolling surfaces at boundary layers. |
FILED | Wednesday, February 17, 2016 |
APPL NO | 15/045749 |
ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 125/26 (20130101) C10M 133/46 (20130101) C10M 141/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657489 | Harper |
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FUNDED BY |
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APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | David William Harper (Madison, Alabama) |
ABSTRACT | A structural support having fractal-stiffening and method of fabricating the support is presented where an optimized location of at least three nodes is predetermined prior to fabricating the structural support where a first set of webs is formed on one side of the support and joined to the nodes to form a first pocket region. A second set of webs is formed within the first pocket region forming a second pocket region where the height of the first set of webs extending orthogonally from the side of the support is greater than the second set of webs extending orthogonally from the support. |
FILED | Monday, June 15, 2015 |
APPL NO | 14/739539 |
ART UNIT | 3635 — Static Structures, Supports and Furniture |
CURRENT CPC | Aeroplanes; Helicopters B64C 1/08 (20130101) B64C 1/12 (20130101) Structural Elements; Building Materials E04C 2/08 (20130101) E04C 2/32 (20130101) E04C 2/384 (20130101) E04C 2/427 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 7/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09657858 | Ramspacher et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Daniel J. Ramspacher (Washington, District of Columbia); James A. Richard (Grant, Alabama) |
ABSTRACT | A non-pyrotechnic, normally-closed, zero-leak valve is a replacement for the pyrovalve used for both in-space and launch vehicle applications. The valve utilizes a magnetostrictive alloy for actuation, rather than pyrotechnic charges. The alloy, such as Terfenol-D, experiences magnetostriction, i.e. a gross elongation, when exposed to a magnetic field. This elongation fractures a parent metal seal, allowing fluid flow through the valve. The required magnetic field is generated by redundant coils that are isolated from the working fluid. |
FILED | Monday, September 28, 2015 |
APPL NO | 14/868041 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 17/40 (20130101) Original (OR) Class F16K 31/0679 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/1744 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658251 | Cairns et al. |
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FUNDED BY |
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APPLICANT(S) | WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia) |
ASSIGNEE(S) | WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia) |
INVENTOR(S) | Darran Robert Cairns (Morgantown, West Virginia); Wade W. Huebsch (Morgantown, West Virginia); Konstantinos A. Sierros (Morgantown, West Virginia); Matthew S. Shafran (Austin, Texas) |
ABSTRACT | Disclosed are various embodiments of methods and systems related to stimulus responsive nanoparticles. In one embodiment includes a stimulus responsive nanoparticle system, the system includes a first electrode, a second electrode, and a plurality of elongated electro-responsive nanoparticles dispersed between the first and second electrodes, the plurality of electro-responsive nanorods configured to respond to an electric field established between the first and second electrodes. |
FILED | Friday, May 01, 2015 |
APPL NO | 14/701608 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/30 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660623 | Prokop et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Norman Prokop (South Euclid, Ohio); Michael Krasowski (Chagrin Falls, Ohio) |
ABSTRACT | A two input time domain correlator may perform analog correlation. In order to achieve high throughput rates with reduced or minimal computational overhead, the input data streams may be hard limited through adaptive thresholding to yield two binary bit streams. Correlation may be achieved through the use of a Hamming distance calculation, where the distance between the two bit streams approximates the time delay that separates them. The resulting Hamming distance approximates the correlation time delay with high accuracy. |
FILED | Monday, December 02, 2013 |
APPL NO | 14/094006 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 17/15 (20130101) Pulse Technique H03K 5/125 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660680 | Krasowski et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Michael J. Krasowski (Chagrin Falls, Ohio); Norman F. Prokop (South Euclid, Ohio); Lawrence C. Greer, III (Avon, Ohio); Jennifer M. Nappier (Bay Village, Ohio) |
ABSTRACT | An apparatus and method are provided for communicating over power lines. The apparatus includes a coupling modem that is situated between a power line and a device. The coupling modem is configured to demodulate a signal received from the power line into a sine signal and a cosine signal. The coupling modem is also configured to modulate a communicated bit stream received from the device into a transmitted signal in order to impose the transmitted signal onto the power line. |
FILED | Friday, July 31, 2015 |
APPL NO | 14/815189 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Transmission H04B 1/38 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660908 | Murphy |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Brandon M. Murphy (Huntsville, Alabama) |
ABSTRACT | A method and apparatus for processing a plurality of data packets. A data packet is received. A determination is made as to whether a portion of the data packet follows a selected digital recorder standard protocol based on a header of the data packet. Raw data in the data packet is converted into human-readable information in response to a determination that the portion of the data packet follows the selected digital recorder standard protocol. |
FILED | Monday, October 27, 2014 |
APPL NO | 14/524546 |
ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 11/321 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0829 (20130101) H04L 43/0835 (20130101) H04L 45/74 (20130101) Original (OR) Class H04L 47/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 09655864 | Freyman et al. |
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FUNDED BY |
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APPLICANT(S) | Toby Freyman (Lexington, Massachusetts); Quynh Pham (Metheun, Massachusetts); Robert F. Mulligan (Arlington, Massachusetts); Abby N. Picard (Jamaica Plain, Massachusetts); Xuri Yan (Brighton, Massachusetts) |
ASSIGNEE(S) | Arsenal Medical, Inc. (Watertown, Massachusetts) |
INVENTOR(S) | Toby Freyman (Lexington, Massachusetts); Quynh Pham (Metheun, Massachusetts); Robert F. Mulligan (Arlington, Massachusetts); Abby N. Picard (Jamaica Plain, Massachusetts); Xuri Yan (Brighton, Massachusetts) |
ABSTRACT | The present invention relates generally to the field of electrospun fibers. In particular, the present invention relates to core-sheath fibers and related electrospinning methods. The fibers of the invention comprise poorly water soluble drugs and/or proteins. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/211900 |
ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/70 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 38/1825 (20130101) A61K 47/34 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/34 (20130101) D01D 5/0069 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 15/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658301 | Walsworth |
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FUNDED BY |
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APPLICANT(S) | Ronald Walsworth (Newton, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Ronald Walsworth (Newton, Massachusetts) |
ABSTRACT | Absorption based detection of spin states of spin impurities within a solid-state spin system, such as NV centers in diamond, is implemented by measuring the absorption intensity of an optical signal applied to the spin impurities, i.e. change in intensity of the optical signal after the signal has been transmitted through the solid-state spin system. During optical excitation of the spin impurities, microwave pulses are applied to the sample at a frequency tuned to the ESR frequency. The relative populations of the spin states of the impurities, which provides information regarding variables of interest such as an external magnetic field or a quantum information protocol, is determined from the ratio of the absorption intensity of the optical signal when the microwave pulses are turned on, to the absorption intensity of the optical signal when the microwave pulses turned off. |
FILED | Tuesday, June 12, 2012 |
APPL NO | 14/125072 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/323 (20130101) Original (OR) Class G01R 33/1284 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09660721 | Polzik et al. |
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FUNDED BY |
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APPLICANT(S) | Kobenhavns Universitet (Copenhagen K, Denmark) |
ASSIGNEE(S) | Kobenhavns Universitet (Copenhagen K, Denmark); Danmarks Tekniske Universitet (Kongens Lyngby, Denmark); National Institute of Standards and Technology, The United States Of America, as Represented by The Secretary Of Commerce (Washington, District of Columbia) |
INVENTOR(S) | Eugene Simon Polzik (Copenhagen O, Denmark); Albert Schliesser (Copenhagen K, Denmark); Silvan Schmid (Copenhagen O, Denmark); Anders Sondberg Sorensen (Rodovre, Denmark); Jacob M. Taylor (Washington, District of Columbia); Koji Usami (Nakahara-ku, Japan); Tolga Bagci (Ankara, Turkey); Anders Simonsen (Copenhagen NV, Denmark); Luis Guillermo Villanueva (Neuchatel, Switzerland); Emil Zeuthen (Copenhagen N, Denmark); Juergen Appel (Soberg, Denmark) |
ABSTRACT | An optical detector for detecting radio frequency (RF) signals, the optical detector comprising a light source and a photodetector, and an electrical circuit comprising a position dependent capacitor and a bias voltage source adapted for providing a bias voltage for biasing the position dependent capacitor, the position dependent capacitor comprising an electrode and a membrane being displaceable in reaction to RF signals incident on the membrane, the membrane being metallized, has a thickness of less than 1 μm and a quality factor, Qm, of at least 20,000, and the distance between the membrane and the electrode being less than 10 μm. |
FILED | Friday, July 11, 2014 |
APPL NO | 14/328871 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Transmission H04B 10/00 (20130101) Original (OR) Class H04B 2210/006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 09656639 | Brooks |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Ernie Brooks (Glynco, Georgia) |
ABSTRACT | Aspects of the disclosure provide a system and methods for inducing a skid in a vehicle. The system includes a mobile controller corresponding to a vehicle and communicatively coupled to a brake system of the vehicle, and a remote controller in wireless communication with the mobile controller. The remote controller is configured to receive a selection of the mobile controller for issuance of a braking command including a braking setting. In response to receipt of the braking command, the selected mobile controller is configured to operate the brake system of the vehicle to induce a skid in the vehicle according to the braking setting. |
FILED | Friday, September 30, 2016 |
APPL NO | 15/281703 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Vehicle Brake Control Systems or Parts Thereof; Brake Control Systems or Parts Thereof, in General; Arrangement of Braking Elements on Vehicles in General; Portable Devices for Preventing Unwanted Movement of Vehicles; Vehicle Modifications to Facilitate Cooling of Brakes B60T 7/18 (20130101) Original (OR) Class B60T 8/176 (20130101) B60T 2270/10 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0016 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658139 | Hering et al. |
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FUNDED BY |
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APPLICANT(S) | TSI Incorporated (Shoreview, Minnesota) |
ASSIGNEE(S) | TSI INCORPORATED (Shoreview, Minnesota); AEROSOL DYNAMICS INC. (Berkley, California) |
INVENTOR(S) | Susanne V. Hering (Berkeley, California); Gregory S. Lewis (Berkeley, California); Arantzazu Eiguren Fernandez (El Cerrito, California); Frederick Quant (Shoreview, Minnesota); Kenneth R. Farmer, II (Lake Elmo, Minnesota) |
ABSTRACT | A system and a method is described herein for the collection of small particles in a concentrated manner, whereby particles are deposited onto a solid surface or collected into a volume of liquid. The collected samples readily interface to any of a number of different elemental, chemical, or biological or other analysis techniques. |
FILED | Wednesday, August 28, 2013 |
APPL NO | 14/012818 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2202 (20130101) Original (OR) Class G01N 1/2208 (20130101) G01N 1/2211 (20130101) G01N 15/065 (20130101) G01N 2001/2217 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09659189 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Wenke Lee (Atlanta, Georgia); Alexandra Boldyreva (Atlanta, Georgia); Chung Pak Ho (Atlanta, Georgia); Billy Lau (Atlanta, Georgia); Chengyu Song (Atlanta, Georgia) |
ABSTRACT | The disclosed technology includes techniques for improving data privacy in mobile communications over public cloud services. According to certain implementations, a novel conceptual layer may be interposed between the “application” layer and the “user” layer. In some implementations, the conceptual layer may be at least partially embodied by a transparent window or pane overlaid on top of existing app graphical user interfaces to: (1) intercept plaintext user input before transforming the input and feeding it to an underlying app; and (2) reverse transform output data from the app before displaying the plaintext data to the user. Accordingly, the conceptual layer may serve as a protective layer while preserving the original application workflow and look-and-feel. |
FILED | Tuesday, October 14, 2014 |
APPL NO | 14/513680 |
ART UNIT | 2492 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/6263 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0435 (20130101) Wireless Communication Networks H04W 12/00 (20130101) H04W 12/02 (20130101) H04W 88/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 09656262 | Paliwal et al. |
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FUNDED BY |
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APPLICANT(S) | Saurabh Paliwal (Mountain View, California); Zhizhong Yin (Timonium, Maryland); Raymond Cheong (Timonium, Maryland) |
ASSIGNEE(S) | EUVEDA BIOSCIENCES, INC. (Timonium, Maryland) |
INVENTOR(S) | Saurabh Paliwal (Mountain View, California); Zhizhong Yin (Timonium, Maryland); Raymond Cheong (Timonium, Maryland) |
ABSTRACT | Microfluidic devices have been developed to perform a range of high-throughput biochemical and cell-based assays over recent years. A design for a microfluidic device has been developed that resembles a microtiter plate, by placing the test chambers (each test chamber contains cells) and top-loading drug inlets (at least one per test chamber) in a grid according to the ANSI/SBS standards, yet offers the miniaturization and fluid handling advantages of microfluidics. This ensures that the device design is compatible with fluid handling and imaging equipment already in use for drug screening. A range of topologies have been determined that allow placement of various elements of this microfluidic network within the grid alignment constraints. A resistance equalization methodology has also been developed to reduce variability across assays run in different chambers of the microfluidic device. Additionally, it offers orders of magnitude miniaturization over multiwell plates, and potentially more reliable fluid handling. |
FILED | Tuesday, June 10, 2014 |
APPL NO | 14/301319 |
ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 2300/0829 (20130101) B01L 2300/0864 (20130101) B01L 2300/0874 (20130101) B01L 2300/0883 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658040 | Vasudevan et al. |
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FUNDED BY |
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APPLICANT(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
INVENTOR(S) | Srikanth Vasudevan (Shelton, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
ABSTRACT | Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics. |
FILED | Tuesday, June 21, 2016 |
APPL NO | 15/188093 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Weapon Sights; Aiming F41G 7/222 (20130101) F41G 7/2293 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) F42B 10/42 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09658314 | Parks et al. |
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FUNDED BY |
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APPLICANT(S) | Brandon Scott Parks (South Park, Pennsylvania); Walter J. Keller, III (Bridgeville, Pennsylvania); Jennting Timothy Hsu (Bethel Park, Pennsylvania) |
ASSIGNEE(S) | Nokomis, Inc. (Charleroi, Pennsylvania) |
INVENTOR(S) | Brandon Scott Parks (South Park, Pennsylvania); Walter J. Keller, III (Bridgeville, Pennsylvania); Jennting Timothy Hsu (Bethel Park, Pennsylvania) |
ABSTRACT | A system for identifying a real-world geographic location of an emission source emitting electromagnetic energy includes a platform configured for movement and an apparatus disposed on the platform and configured to collect and process, in a passive manner and during movement of the platform, at least a pair of successive samples of the electromagnetic energy emission and define angular and spatial coordinates of the emission source. The apparatus includes at least a pair of antennas, a receiver coupled to antennas and a processor executing a predetermined logic. |
FILED | Friday, March 02, 2012 |
APPL NO | 13/410586 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/04 (20130101) Original (OR) Class G01S 5/0221 (20130101) G01S 5/0278 (20130101) G01S 5/0284 (20130101) G01S 5/0294 (20130101) G01S 19/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 09655366 | Beck et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Wonderful Orchards, LLC (Shafter, California) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Wonderful Orchards, LLC (Shafter, California) |
INVENTOR(S) | John J Beck (Rocklin, California); Bradley S Higbee (Shafter, California) |
ABSTRACT | The present invention relates to formulations of volatile organic compounds having effects on the navel orangeworm moth (NOW). In some embodiments, the blends of volatile organic compounds attract navel orangeworm moths. In other embodiments, the blends disrupt ovipositional activity of the female NOW. The invention also relates to traps baited with any one or more of the disclosed volatile blends, which are effective for controlling NOW. |
FILED | Friday, September 18, 2015 |
APPL NO | 14/858654 |
ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 31/02 (20130101) A01N 31/02 (20130101) A01N 31/04 (20130101) A01N 31/04 (20130101) A01N 31/04 (20130101) A01N 31/04 (20130101) A01N 31/04 (20130101) A01N 31/04 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 35/04 (20130101) A01N 35/04 (20130101) A01N 35/04 (20130101) A01N 35/04 (20130101) A01N 35/04 (20130101) A01N 35/04 (20130101) A01N 35/04 (20130101) A01N 37/02 (20130101) A01N 37/02 (20130101) A01N 37/02 (20130101) A01N 37/02 (20130101) A01N 37/10 (20130101) A01N 37/10 (20130101) A01N 37/10 (20130101) A01N 37/14 (20130101) A01N 37/40 (20130101) A01N 37/40 (20130101) A01N 37/40 (20130101) A01N 37/40 (20130101) A01N 43/90 (20130101) Original (OR) Class A01N 43/90 (20130101) A01N 43/90 (20130101) A01N 43/90 (20130101) A01N 43/90 (20130101) A01N 49/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 09655535 | Narayan et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California) |
ABSTRACT | A system and method to target a biological rhythm disorder, such as a heart rhythm disorder include processing cardiac signals via a computing device to determine a shape in a region of tissue defined by a source associated with the biological rhythm disorder that migrates spatially on or within the shape, and identifying at least one portion of the tissue proximate to the shape to enable selective modification of the at least one portion of tissue in order to terminate or alter the heart rhythm disorder. |
FILED | Thursday, February 18, 2016 |
APPL NO | 15/047266 |
ART UNIT | 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/042 (20130101) A61B 5/046 (20130101) A61B 5/0464 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/4029 (20130101) A61B 5/4064 (20130101) A61B 5/4839 (20130101) A61B 18/1492 (20130101) A61B 2018/00357 (20130101) A61B 2018/00577 (20130101) A61B 2018/00839 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 09655523 | Hillman et al. |
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FUNDED BY |
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APPLICANT(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Sean A. Burgess (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Sean A. Burgess (New York, New York) |
ABSTRACT | Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM). |
FILED | Tuesday, December 29, 2009 |
APPL NO | 12/655325 |
ART UNIT | 3737 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0064 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/0071 (20130101) A61B 5/0073 (20130101) A61B 5/0075 (20130101) A61B 5/0088 (20130101) A61B 5/444 (20130101) A61B 5/445 (20130101) A61B 2562/0238 (20130101) A61B 2562/0242 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/457 (20130101) G01J 3/2889 (20130101) Optical Elements, Systems, or Apparatus G02B 23/2476 (20130101) G02B 26/101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 23, 2017.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
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THE PANEL
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FUNDED BY
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APPLICANT(S) and ASSIGNEES
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Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
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FILED
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
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CURRENT CPC
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The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
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