FedInvent™ Patents

Patent Details for Tuesday, June 06, 2017

This page was updated on Monday, March 27, 2023 at 05:14 AM GMT

Department of Health and Human Services (HHS)

09668463 — Mouse model for engraftment potential

US 09668463	Thomson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Cellular Dynamics International, Inc. (Madison, Wisconsin)
ASSIGNEE(S)
INVENTOR(S)	James Thomson (Madison, Wisconsin); Brian McIntosh (Verona, Wisconsin); Igor Slukvin (Madison, Wisconsin)
ABSTRACT	Disclosed herein is the generation of a permissive murine strain (NSGW) that exhibits enhanced levels of human chimerism without pre-conditioning.
FILED	Thursday, October 02, 2014
APPL NO	15/026856
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) A01K 67/0271 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101)
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09668666 — System and method for reconstructing cardiac activation information

US 09668666	Narayan et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); Topera, Inc. (Menlo Park, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California); Ruchir Sehra (Scottsdale, Arizona)
ABSTRACT	In a system and method for reconstructing cardiac activation information, an analysis cardiac signal and a reference cardiac signal are accessed and processed to determine a first point of change in the analysis cardiac signal at which a derivative of the analysis cardiac signal diverges with respect to a derivative of the reference cardiac signal. The signals are processed to determine a second point of change in the analysis cardiac signal at which a different derivative of the analysis cardiac signal with respect to a different derivative of the reference cardiac signal. An activation onset time is assigned in the analysis cardiac signal at a point based on a mathematical association of the first point of change and the second point of change to define cardiac activation indicating a beat in the analysis cardiac signal.
FILED	Tuesday, November 17, 2015
APPL NO	14/944096
ART UNIT	3766 — Semiconductors/Memory
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0255 (20130101) A61B 5/0468 (20130101) A61B 5/0472 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/7207 (20130101) A61B 5/7278 (20130101)
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09668804 — Automated cell patch clamping method and apparatus

US 09668804	Kodandaramaiah et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) NIH Office of the Director (NIHOD) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	Suhasa Bangalore Kodandaramaiah (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Crag Richard Forest (Atlanta, Georgia); Brian Yichiun Chow (Cambridge, Massachusetts); Giovanni Talei Franzesi (Boston, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Suhasa Bangalore Kodandaramaiah (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Crag Richard Forest (Atlanta, Georgia); Brian Yichiun Chow (Cambridge, Massachusetts); Giovanni Talei Franzesi (Boston, Massachusetts)
ABSTRACT	In an automated methodology for carrying out in vivo cell patch clamping, a cell patch clamping device is automatically moved into position and targeted to a neuron. Neuron contact is determined by analyzing the temporal series of measured resistance levels at the cell patch clamping device as it is moved. The difference between successive resistance levels is computed and compared to a threshold, which must be exceeded for a minimum number of computations before neuron contact is assumed. Pneumatic control methods are used to achieve gigaseal formation and cell break-in, leading to whole-cell patch clamp formation. An automated robotic system capable of performing this methodology automatically performs patch clamping in vivo, automatically detecting cells by analyzing the temporal sequence of electrode impedance changes. By continuously monitoring the patching process and rapidly executing actions triggered by specific measurements, the robot can rapidly find neurons in the living brain and establish recordings.
FILED	Tuesday, November 13, 2012
APPL NO	13/676082
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0538 (20130101) A61B 5/04001 (20130101) A61B 5/6885 (20130101) A61B 18/14 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 2503/40 (20130101)
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09668825 — Dental and endodontic filling materials and methods

US 09668825	Chow et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	ADA Foundation (Chicago, Illinois)
ASSIGNEE(S)	ADA Foundation (Chicago, Illinois)
INVENTOR(S)	Laurence C. Chow (Potomac, Maryland); Shozo Takagi (Gaithersburg, Maryland)
ABSTRACT	Disclosed are endodontic filling materials and methods. A method for filling a dental root canal may include providing a hydrosetting filling material and inserting the hydrosetting filling material into the dental root canal, the material setting in the root canal to form a biocompatible filling. The hydrosetting filling material comprises a hydrogel former and a filler. The hydrogel former is at least one of a reactive organic hydrogel formers, an inorganic hydrogel formers, and a non-reactive organic hydrogel formers, and the filler is at least one of a self-hardening and a non-hardening filler. Plural filling material precursor compositions that collectively contain hydrogel formers and fillers may be provided.
FILED	Tuesday, July 21, 2015
APPL NO	14/805137
ART UNIT	1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 5/04 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 6/0038 (20130101)
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09668889 — Percutaneous osseointegrated prosthetic implant system

US 09668889	Holt et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Brian Mueller Holt (Topanga, California); Kent N. Bachus (Salt Lake City, Utah); Sujee Jeyapalina (Salt Lake City, Utah); James Peter Beck (Salt Lake City, Utah); Roy Bloebaum (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Brian Mueller Holt (Topanga, California); Kent N. Bachus (Salt Lake City, Utah); Sujee Jeyapalina (Salt Lake City, Utah); James Peter Beck (Salt Lake City, Utah); Roy Bloebaum (Salt Lake City, Utah)
ABSTRACT	An implant system for securing a prosthesis to a selected bone of a subject including a stem and an abutment. The stem includes a porous region that promotes osseointegration of the selected bone following implantation of the stem. The abutment is secured to the stem and is configured for secure attachment to the prosthesis. The stem and the abutment include ultra-low friction and/or highly polished surfaces at select locations that inhibit bio-adhesion.
FILED	Wednesday, June 06, 2012
APPL NO	14/123719
ART UNIT	3738 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 2008/0046 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/78 (20130101) Original (OR) Class A61F 2/2814 (20130101) A61F 2002/3694 (20130101) A61F 2002/7887 (20130101) A61F 2002/30013 (20130101) A61F 2002/30332 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2270/0421 (20130101)
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09668988 — Controlled release oral pharmaceutical dosage forms comprising MGBG

US 09668988	McKearn et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Pathologica LLC (Burlingame, California)
ASSIGNEE(S)	Pathologica LLC (San Francisco, California)
INVENTOR(S)	John McKearn (Saint Louis, Missouri); Jeremy Blitzer (San Francisco, California)
ABSTRACT	Disclosed herein are controlled-release oral pharmaceutical dosage forms comprising MGBG, and their application for the improved treatment of diseases with reduced side effects and/or longer time at maximum concentration.
FILED	Tuesday, September 09, 2014
APPL NO	14/480847
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/2054 (20130101) A61K 9/2846 (20130101) A61K 9/4808 (20130101) A61K 9/4866 (20130101) A61K 9/4891 (20130101) A61K 9/5026 (20130101) A61K 9/5047 (20130101) A61K 31/155 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 211/13 (20130101) C07C 243/16 (20130101) C07C 251/12 (20130101) C07C 251/78 (20130101)
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09669011 — Methods of use of cyclopamine analogs

US 09669011	Castro et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Infinity Pharmaceuticals, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	Infinity Pharmaceuticals, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Alfredo C. Castro (Winchester, Massachusetts); Michael J. Grogan (Winchester, Massachusetts); Karen J. McGovern (Groton, Massachusetts); Martin R. Tremblay (Melrose, Massachusetts)
ABSTRACT	The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
FILED	Monday, August 31, 2015
APPL NO	14/841001
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/17 (20130101) A61K 31/56 (20130101) A61K 31/58 (20130101) A61K 31/69 (20130101) A61K 31/196 (20130101) A61K 31/198 (20130101) A61K 31/454 (20130101) A61K 31/519 (20130101) A61K 31/573 (20130101) A61K 31/664 (20130101) A61K 31/704 (20130101) A61K 31/4355 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7076 (20130101) A61K 38/21 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Heterocyclic Compounds C07D 307/94 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 491/04 (20130101) C07D 491/10 (20130101) C07D 491/048 (20130101) C07D 491/107 (20130101) Steroids C07J 69/00 (20130101)
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09669016 — Antiparasitic effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives

US 09669016	Maldonado et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); UNIVERSITY OF SASKATCHEWAN (Saskatoon, Canada)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); UNIVERSITY OF SASKATCHEWAN (Saskatchewan, Canada)
INVENTOR(S)	Rosa A. Maldonado (El Paso, Texas); Miguel A. Vasquez (El Paso, Texas); Jonathan R. Dimmock (Saskatoon, Canada); Umashankar Das (Saskatoon, Canada)
ABSTRACT	Embodiments are directed to compositions and methods for treating parasitic infections. Compounds have been identified from a library of anti-cancer drugs that serve as suitable agents for targeting trypanosomatids.
FILED	Monday, June 27, 2016
APPL NO	15/193589
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 31/132 (20130101) A61K 31/4545 (20130101) Original (OR) Class A61K 45/06 (20130101)
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09669036 — Modulation of reactivation of a latent virus

US 09669036	Roizman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S)	Bernard Roizman (Chicago, Illinois); Guoying Zhou (Madison, Wisconsin); Te Du (Chicago, Illinois)
ABSTRACT	The disclosure relates to methods of controlling the state of a virus (lytic or lysogenic) in an individual, such as a method of reactivating a latent virus in an individual, comprising administering one or more agents that modulates the activity of signal transducer and activator of transcription 3 (STAT3) or any of p300, CBP or p300/CBP. Also contemplated are methods further comprising administering an HDAC modulating agent, such as an HDAC inhibiting agent or an HDAC activating agent.
FILED	Wednesday, May 14, 2014
APPL NO	14/891200
ART UNIT	1672 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/40 (20130101) A61K 31/165 (20130101) A61K 31/167 (20130101) A61K 31/185 (20130101) A61K 31/255 (20130101) A61K 31/436 (20130101) A61K 31/517 (20130101) A61K 31/4045 (20130101) A61K 31/4192 (20130101) A61K 31/4375 (20130101) A61K 31/4402 (20130101) A61K 31/4406 (20130101) A61K 31/4745 (20130101) A61K 31/5377 (20130101) Original (OR) Class A61K 45/06 (20130101)
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09669059 — Butyrogenic bacteria as probiotics to treat clostridium difficile

US 09669059	Wang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S)	Gary P. Wang (Gainesville, Florida)
ABSTRACT	The subject invention pertains to the use of certain bacterial strains, particularly butyrogenic bacteria, for preparing a composition to treat and/or prevent Clostridium difficile infection. In particular, the invention relates to the use of butyrate-producing anaerobic fermenters of gut commensals in pharmaceutical or food compositions.
FILED	Sunday, March 09, 2014
APPL NO	14/773432
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/135 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Indexing Scheme Relating to Lactic or Propionic Acid Bacteria Used in Foodstuffs or Food Preparation A23Y 2240/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/74 (20130101) A61K 35/741 (20130101) Original (OR) Class A61K 35/744 (20130101) A61K 35/744 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101)
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09669070 — Treatment and prevention of radiation injury using MFG-E8

US 09669070	Wang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Feinstein Institute For Medical Research (Manhasset, New York)
ASSIGNEE(S)	The Feinstein Institute For Medical Research (Manhasset, New York)
INVENTOR(S)	Ping Wang (Roslyn, New York)
ABSTRACT	Methods and compositions are disclosed for treating and preventing radiation injury using milk fat globule epidermal growth factor-factor VIII (MFG-E8).
FILED	Wednesday, September 10, 2014
APPL NO	14/481959
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1808 (20130101) Original (OR) Class
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09669092 — Antagonism of the VIP signaling pathway

US 09669092	Waller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Edmund K. Waller (Atlanta, Georgia); Jian-Ming Li (Atlanta, Georgia); Mohammad S. Hossain (Liburn, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia)
INVENTOR(S)	Edmund K. Waller (Atlanta, Georgia); Jian-Ming Li (Atlanta, Georgia); Mohammad S. Hossain (Liburn, Georgia)
ABSTRACT	Inhibition of the VIP signaling pathway using VIP antagonists is contemplated. Methods of treating or preventing a viral infection comprising administering a VIP antagonist to a subject in need thereof are also contemplated.
FILED	Tuesday, January 31, 2012
APPL NO	13/979003
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/17 (20130101) A61K 38/04 (20130101) A61K 38/16 (20130101) A61K 38/2278 (20130101) A61K 39/245 (20130101) A61K 39/3955 (20130101) Original (OR) Class
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09669094 — Methods for increasing susceptibility to apoptosis by administering an inhibitor of kallikrein 6 polypeptide activity

US 09669094	Scarisbrick
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Isobel A. Scarisbrick (Rochester, Minnesota)
ABSTRACT	This document provides methods and materials involved in modulating a cell's ability to be resistant to apoptosis. For example, methods and materials for exposing cells to KLK6 polypeptides, or increased KLK6 polypeptide activity, to promote resistance to apoptosis are provided. In addition, methods and materials for reducing the ability of KLK6 polypeptides to promote resistance to apoptosis are provided.
FILED	Thursday, August 08, 2013
APPL NO	13/962686
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 38/4853 (20130101) A61K 39/39558 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6445 (20130101) Enzymes C12Y 304/21008 (20130101)
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09669108 — Meditopes and meditope-binding antibodies and uses thereof

US 09669108	Williams et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	City of Hope (Duarte, California)
ASSIGNEE(S)	City of Hope (Duarte, California)
INVENTOR(S)	John C. Williams (Monrovia, California); David A. Horne (Duarte, California); Yuelong Ma (Duarte, California); Heng Wei Chang (Foster City, California); Joshua M. Donaldson (Lumberton, New Jersey); Cindy Zer (Duarte, California); Krzysztof Bzymek (Pasadena, California); Kendra N. Avery (Pasadena, California); Jun Xie (Duarte, California)
ABSTRACT	Antibodies and meditopes that bind to the antibodies are provided, as well as complexes, compositions and combinations containing the meditopes and antibodies, and methods of producing, using, testing, and screening the same, including therapeutic and diagnostic methods and uses.
FILED	Wednesday, August 06, 2014
APPL NO	14/453586
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48346 (20130101) A61K 47/48669 (20130101) A61K 47/48746 (20130101) Original (OR) Class A61K 51/1087 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/18 (20130101) C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 2299/00 (20130101) C07K 2317/34 (20130101) C07K 2317/40 (20130101) C07K 2317/55 (20130101) C07K 2317/92 (20130101) C07K 2317/567 (20130101) C07K 2317/622 (20130101)
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09669112 — Animal model of neuronal injury

US 09669112	Akassoglou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The J. David Gladstone Institutes (San Francisco, California)
ASSIGNEE(S)	THE J. DAVID GLADSTONE INSTITUTES (San Francisco, California)
INVENTOR(S)	Katerina Akassoglou (San Francisco, California); Jae Kyu Ryu (San Francisco, California)
ABSTRACT	The present invention provides non-human animal models of neuronal injury and/or cognitive dysfunction and methods of making and using such animal models. The animal models of the invention are particularly suited to assessing neurodegeneration in selected regions of interest in the CNS, and thus especially useful for testing the therapeutic efficacy of agents targeting neurodegeneration associated with aging, neurodegenerative diseases, autoimmunity and trauma (e.g., ischemia).
FILED	Wednesday, November 20, 2013
APPL NO	14/646429
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) A01K 2207/10 (20130101) A01K 2227/105 (20130101) A01K 2267/035 (20130101) A01K 2267/0318 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Original (OR) Class Peptides C07K 14/75 (20130101)
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09669129 — Ophthalmic and contact lens solutions using carnitine

US 09669129	Smith
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	FXS VENTURES, LLC (Salem, New Hampshire)
ASSIGNEE(S)	FXS VENTURES, LLC (Salem, New Hampshire)
INVENTOR(S)	Francis X. Smith (Salem, New Hampshire)
ABSTRACT	The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R₁, R₂, R₃and R₄are —H or low molecular weight radicals, and R₅is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
FILED	Wednesday, September 02, 2015
APPL NO	14/843066
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 33/12 (20130101) A01N 37/44 (20130101) A01N 43/38 (20130101) A01N 43/50 (20130101) A01N 47/44 (20130101) Purses; Luggage; Hand Carried Bags A45C 11/005 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/18 (20130101) A61L 12/12 (20130101) Original (OR) Class A61L 12/086 (20130101) A61L 12/143 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 7/1233 (20130101) Optical Elements, Systems, or Apparatus G02B 1/18 (20150115)
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09669209 — Method of making a flexible circuit electrode array

US 09669209	Neysmith et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Second Sight Medical Products, Inc. (Sylmar, California)
ASSIGNEE(S)	Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S)	Jordan Neysmith (Mountain View, California); Robert Greenberg (Los Angeles, California); James Little (Arvada, Colorado); Brian Mech (Santa Clarita, California); Neil Talbot (La Crescenta, California); Qingfang Yao (Valencia, California); Dao Min Zhou (Saugus, California)
ABSTRACT	A flexible circuit electrode array with more than one layer of metal traces comprising: a polymer base layer; more than one layer of metal traces, separated by polymer layers, deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; and a polymer top layer deposited on said polymer base layer and said metal traces. Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow.
FILED	Monday, April 18, 2016
APPL NO	15/132177
ART UNIT	3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 1/0543 (20130101) Original (OR) Class A61N 1/36046 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) H05K 1/118 (20130101) H05K 3/0014 (20130101) H05K 3/0017 (20130101) H05K 3/0041 (20130101) H05K 3/188 (20130101) H05K 3/388 (20130101) H05K 3/4644 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49156 (20150115) Y10T 29/49158 (20150115)
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09669232 — Method for non-invasive brain stimulation

US 09669232	Khizroev et al.
FUNDED BY	Department of Defense (DOD) Defense MicroElectronics Activity (DMEA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF)
APPLICANT(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S)	Sakhrat Khizroev (Coral Gables, Florida); Madhavan P. N. Nair (Coral Gables, Florida)
ABSTRACT	Magneto-electric nanoparticles in a subject interact with an external magnetic field to cause stimulation of neural networks in the subject. Electric signals in the neural network are coupled to magnetic dipoles induced in the nanoparticles to cause changes in electric pulse sequences of the subject's brain.
FILED	Thursday, February 04, 2016
APPL NO	15/015760
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/40 (20130101) A61N 2/02 (20130101) A61N 2/006 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0045 (20130101)
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09669345 — Systems and methods for controlling particulate release from large equipment

US 09669345	Esswein et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Eric J. Esswein (Conifer, Colorado); Michael Breitenstein (Cincinnati, Ohio); John E. Snawder (Williamstown, Kentucky); Michael Gerard Gressel (Cincinnati, Ohio); Jerry L. Kratzer (Cincinnati, Ohio)
ABSTRACT	A containment system for reducing the release of harmful respirable particles through surface openings in equipment that carries sand includes a filter-receiving member configured to be coupled over an opening in a surface of the equipment and a filter member configured to be coupled to the filter-receiving member. The filter-receiving member can have a first side, a second side, and a passageway extending from the first side to the second side. The filter can have a porosity that permits air to flow through the filter member and restricts the flow of solid particulates.
FILED	Monday, January 11, 2016
APPL NO	14/992963
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 46/02 (20130101) Original (OR) Class B01D 46/4272 (20130101) B01D 2275/203 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4987 (20150115) Y10T 29/49826 (20150115)
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09670141 — (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and related compounds as GABA aminotransferase inactivators for the treatment of epilepsy, addiction and hepatocellular carcinoma

US 09670141	Silverman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Richard B. Silverman (Winnetka, Illinois); Kenji Takaya (Osaka, Japan); Hoang V. Le (Evanston, Illinois); Jose I. Juncosa (Salisbury, Maryland)
ABSTRACT	Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
FILED	Monday, October 10, 2016
APPL NO	15/289480
ART UNIT	1672 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 229/48 (20130101) Original (OR) Class
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09670158 — Amorphous tecovirimat preparation

US 09670158	Tyavanagimatt et al.
FUNDED BY	Department of Health and Human Services (HHS) Assistant Secretary for Preparedness and Response (ASPR) Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S)	SIGA TECHNOLOGIES, INC. (Corvallis, Oregon)
ASSIGNEE(S)	SIGA TECHNOLOGIES, INC. (Corvallis, Oregon)
INVENTOR(S)	Shanthakumar R. Tyavanagimatt (Corvallis, Oregon); N K Peter Samuel (Corvallis, Oregon); Joseph Paz (Corvallis, Oregon); Ying Tan (Walnut Creek, California); Dennis E. Hruby (Albany, Oregon)
ABSTRACT	Disclosed are methods for the preparation of amorphous N-[(3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl]-4-(trifluoromethyl)-benzamide for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus. Also disclosed are methods for the preparation of amorphous solid dispersion of N-[(3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop[f]isoindol-2(1H)-yl]-4-(trifluoromethyl)-benzamide.
FILED	Friday, July 11, 2014
APPL NO	14/903083
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1694 (20130101) A61K 31/4035 (20130101) A61K 47/38 (20130101) Heterocyclic Compounds C07D 209/70 (20130101) Original (OR) Class C07D 209/76 (20130101)
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09670162 — Mitochondrial aldehyde dehyrogenase-2 modulators and methods of use thereof

US 09670162	Yang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junio (Palo Alto, California)
INVENTOR(S)	Wenjin Yang (Foster City, California); Che-Hong Chen (Fremont, California); Daria Mochly-Rosen (Menlo Park, California)
ABSTRACT	The present disclosure provides compounds of formula (I) that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity, and methods of preparing these compounds.
FILED	Thursday, March 13, 2014
APPL NO	14/774071
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 233/66 (20130101) C07C 233/73 (20130101) C07C 233/78 (20130101) C07C 233/87 (20130101) C07C 235/48 (20130101) C07C 235/60 (20130101) C07C 237/32 (20130101) C07C 311/16 (20130101) C07C 311/17 (20130101) C07C 311/29 (20130101) C07C 311/40 (20130101) C07C 317/32 (20130101) C07C 2101/02 (20130101) C07C 2101/04 (20130101) C07C 2101/08 (20130101) Heterocyclic Compounds C07D 213/81 (20130101) C07D 213/82 (20130101) Original (OR) Class C07D 213/89 (20130101) C07D 317/58 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101)
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09670197 — Small molecule modifiers of the Hec1-Nek2 interaction in G2/M

US 09670197	Lee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Wen-Hwa Lee (Irvine, California); Jiewen Zhu (Irvine, California); Chun-Mei Hu (Taipei, Taiwan)
ABSTRACT	Certain embodiments of the present invention provide selected compounds having a molecular structure according to Formula 1: In Formula 1, Z is —CO—, —SO—, or —SO₂—; Ar is phenyl, heteroaryl, or heterocycloalkyl; Het is heteroaryl; R is R″, X, or NR₁R₂; R′ is R₃, or OR₃; R″ is R₄, or OR₄; R₁and R₂are each independently H, alkyl, or acyl; R₃is H, heteroaryl, or alkyl; R₄is H, heteroaryl, or C_nH_2n+1(n>2); and X is F, Br, I, CN, or NO₂. In some embodiments, compounds having a molecular structure according to Formula 1 have the property of inhibiting a growth of a cell line selected from HeLa and MB468 with a sub-micromolar IC₅₀.
FILED	Friday, July 08, 2016
APPL NO	15/205997
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 417/12 (20130101) Original (OR) Class C07D 417/14 (20130101)
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09670198 — Nicotinic acetylcholine receptor modulators

US 09670198	Zaveri et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Astraea Therapeutics (Mountain View, California)
ASSIGNEE(S)	Astraea Therapeutics, LLC (Mountain View, California)
INVENTOR(S)	Nurulain Zaveri (Saratoga, California); Faming Jiang (Mountain View, California)
ABSTRACT	Provided herein are novel and selective high affinity α3β4 nicotinic acetycholine receptor ligands and pharmaceutical compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, drug addiction or pain using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of selectively antagonizing receptors such as, for example, the α3β4 nicotinic acetycholine receptor using the compounds and compositions disclosed herein.
FILED	Tuesday, January 20, 2015
APPL NO	14/601194
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) Heterocyclic Compounds C07D 451/14 (20130101) Original (OR) Class C07D 519/00 (20130101)
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09670225 — HIV-1 protease inhibitors and uses thereof

US 09670225	Ghosh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana); Hiroaki Mitsuya (Kumamoto, Japan)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana); National University Corporation Kumamoto University (Kumamoto, Japan)
INVENTOR(S)	Arun K. Ghosh (West Lafayette, Indiana); Venkateswara Rao Kalapala (Pradesh, India); Hiroaki Mitsuya (Kumamoto, Japan)
ABSTRACT	Various embodiments of the present invention are directed to compounds of the formula (I) or a pharmaceutically acceptable salt, polymorph, prodrug, solvate or clathrate thereof, wherein X¹, X², X³, R¹, R², R¹¹, and n are defined herein. These compounds are useful as inhibitors of HIV-1 protease and, as a result, are useful in the treatment of HIV infection.
FILED	Friday, May 15, 2015
APPL NO	15/311806
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 493/08 (20130101) Original (OR) Class
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09670236 — Class of HDAC inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury

US 09670236	Hukriede et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Neil Hukriede (Allison Park, Pennsylvania); Billy W. Day (Pittsburgh, Pennsylvania); Lee A. McDermott (Pittsburgh, Pennsylvania)
ABSTRACT	Compounds and compositions are provided that inhibit histone deacylase activity and which expand renal progenitor cell populations and improve kidney function in a damaged kidney. Methods of use of the compounds and compositions are provided.
FILED	Thursday, October 31, 2013
APPL NO	14/439855
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 317/22 (20130101) C07C 317/44 (20130101) C07C 321/28 (20130101) C07C 323/16 (20130101) C07C 323/20 (20130101) C07C 323/47 (20130101) C07C 323/52 (20130101) C07C 323/60 (20130101) C07C 323/62 (20130101) Heterocyclic Compounds C07D 213/75 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/4841 (20130101) Original (OR) Class
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09670244 — Oxysterol compounds and the hedgehog pathway

US 09670244	Parhami et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Farhad Parhami (Los Angeles, California); Michael E. Jung (Los Angeles, California); Jennifer R. Dwyer (Los Angeles, California); Khanhlinh Nguyen (Los Angeles, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Farhad Parhami (Los Angeles, California); Michael E. Jung (Los Angeles, California); Jennifer R. Dwyer (Los Angeles, California); Khanhlinh Nguyen (Los Angeles, California)
ABSTRACT	This invention relates, for example, to synthetic oxysterols. Also described are methods for using the compounds, including treating subjects in need thereof, and pharmaceutical compositions and kits for implementing methods of the invention.
FILED	Tuesday, February 27, 2007
APPL NO	12/224430
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Steroids C07J 9/00 (20130101) Original (OR) Class
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09670247 — Contraceptive agents

US 09670247	Blanco et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Gustavo Blanco (Overland Park, Kansas); Gunda I. Georg (St. Paul, Minnesota); Shameem Sultana Syeda (St. Paul, Minnesota)
ASSIGNEE(S)	The University of Kansas (Lawrence, Kansas); Regents of The University of Minnesota (St. Paul, Minnesota)
INVENTOR(S)	Gustavo Blanco (Overland Park, Kansas); Gunda I. Georg (St. Paul, Minnesota); Shameem Sultana Syeda (St. Paul, Minnesota)
ABSTRACT	The invention provides compounds of formula I, II, III, or IV: wherein R¹to R¹¹, X, and Y have any of the values defined in the specification. The compounds inhibit Na, K-ATPase α4 and are useful as contraceptive agents.
FILED	Monday, July 01, 2013
APPL NO	13/932778
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 49/653 (20130101) C07C 49/757 (20130101) C07C 247/14 (20130101) C07C 281/18 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) C07D 249/06 (20130101) Steroids C07J 1/0011 (20130101) C07J 7/00 (20130101) C07J 7/002 (20130101) C07J 17/005 (20130101) C07J 19/00 (20130101) C07J 19/005 (20130101) C07J 41/0005 (20130101) C07J 41/005 (20130101) C07J 41/0027 (20130101) C07J 43/003 (20130101) Original (OR) Class C07J 51/00 (20130101) C07J 71/0026 (20130101)
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09670253 — Antiviral vaccines with improved cellular immunogenicity

US 09670253	Barouch et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Dan H. Barouch (Boston, Massachusetts); Bette T. Korber (Los Alamos, New Mexico); William M. Fischer (Los Alamos, New Mexico)
ABSTRACT	The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects.
FILED	Thursday, February 26, 2015
APPL NO	14/632869
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 39/235 (20130101) A61K 39/275 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/24043 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) C12N 2740/16322 (20130101) C12N 2740/16334 (20130101)
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09670254 — VMP-like sequences of pathogenic Borrelia species and strains

US 09670254	Norris
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Steven J. Norris (Houston, Texas)
ABSTRACT	The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.
FILED	Tuesday, July 21, 2015
APPL NO	14/804882
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/02 (20130101) Peptides C07K 14/20 (20130101) Original (OR) Class C07K 17/08 (20130101) C07K 17/12 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/56911 (20130101) G01N 2333/20 (20130101) G01N 2469/20 (20130101) G01N 2800/26 (20130101)
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09670259 — Method of inhibiting angiogenesis using inhibitors of G-protein-coupled receptor kinase interacting protein-1 (GIT1)

US 09670259	Berk et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Bradford C. Berk (Pittsford, New York); Jinjiang Pang (Rochester, New York); Syamantak Majumder (Rochester, New York)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Bradford C. Berk (Pittsford, New York); Jinjiang Pang (Rochester, New York); Syamantak Majumder (Rochester, New York)
ABSTRACT	The present invention is directed to methods and compositions comprising G-protein-coupled receptor kinase interacting protein-1 (GIT1) inhibitors that are suitable for inhibiting angiogenesis in a subject and treating related conditions.
FILED	Friday, March 14, 2014
APPL NO	14/775936
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) A61K 38/16 (20130101) A61K 38/1709 (20130101) A61K 39/3955 (20130101) A61K 47/48346 (20130101) Peptides C07K 14/4722 (20130101) Original (OR) Class C07K 16/28 (20130101)
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09670264 — Water soluble G-protein coupled receptor

US 09670264	Liu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Renyu Liu (Media, Pennsylvania); Jeffery G Saven (Philadelphia, Pennsylvania); Jose Manuel Perez-Aguilar (New York, New York); Felipe Matsunaga (Olmsted Township, Ohio); Jin Xi (Media, Pennsylvania)
ABSTRACT	Described herein are recombinant integral membrane proteins having multiple transmembrane domains that have been engineered to be less hydrophobic, through alteration of the amino acid sequence of the native protein, but retain the ability to bind their natural ligand. The decreased hydrophobicity of the described proteins makes them more water soluble than the native protein, which allows the described proteins to be expressed in bacteria in large quantities and isolated in the absence of membranes, all while retaining the ability to interact with known ligands.
FILED	Friday, April 25, 2014
APPL NO	14/786578
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 2319/21 (20130101) C07K 2319/42 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/566 (20130101) G01N 2500/04 (20130101)
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09670266 — Method and composition for crystallizing G protein-coupled receptors

US 09670266	Kobilka et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Brian Kobilka (Palo Alto, California); Daniel Rosenbaum (Burlingame, California)
ABSTRACT	Certain embodiments provide a method for crystallizing a GPCR. The method may employ a fusion protein comprising: a) a first portion of a G-protein coupled receptor (GPCR), where the first portion comprises the TM1, TM2, TM3, TM4 and TM5 regions of the GPCR; b) a stable, folded protein insertion; and c) a second portion of the GPCR, where the second portion comprises the TM6 and TM7 regions of the GPCR.
FILED	Friday, April 10, 2015
APPL NO	14/684217
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/705 (20130101) C07K 14/723 (20130101) Original (OR) Class C07K 14/70571 (20130101) C07K 2319/00 (20130101) C07K 2319/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2462 (20130101)
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09670281 — Binding-triggered transcriptional switches and methods of use thereof

US 09670281	Lim et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Wendell A. Lim (San Francisco, California); Leonardo Morsut (San Francisco, California); Kole T. Roybal (San Francisco, California)
ABSTRACT	The present disclosure provides binding-triggered transcriptional switch polypeptides, nucleic acids comprising nucleotide sequences encoding the binding-triggered transcriptional switch polypeptides, and host cells genetically modified with the nucleic acids. The present disclosure also provides chimeric Notch receptor polypeptides, nucleic acids comprising nucleotide sequences encoding the chimeric Notch receptor polypeptides, and host cells transduced and/or genetically modified with the nucleic acids. The present disclosure provides transgenic organisms comprising a nucleic acid encoding a binding triggered transcriptional switch polypeptide and/or a chimeric Notch receptor polypeptide of the present disclosure. Binding triggered transcriptional switch polypeptides and chimeric Notch receptor polypeptides of the present disclosure are useful in a variety of applications, which are also provided.
FILED	Tuesday, April 12, 2016
APPL NO	15/096971
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 48/00 (20130101) Peptides C07K 14/705 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 2317/22 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/32 (20130101) C07K 2319/33 (20130101) C07K 2319/60 (20130101) C07K 2319/74 (20130101)
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09670283 — Depletion of plasmacytoid dendritic cells

US 09670283	Su
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Lishan Su (Chapel Hill, North Carolina)
ABSTRACT	The present invention relates to antibodies targeted to BDCA2 that deplete plasmacytoid dendritic cells (pDC) and methods of using the antibodies to treat disorders associated with pDC.
FILED	Wednesday, April 06, 2016
APPL NO	15/092275
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/39541 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2851 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101)
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09670288 — Osteoprotegerin in neuroprotection

US 09670288	Stankovic et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
ASSIGNEE(S)	Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
INVENTOR(S)	Konstantina Stankovic (Boston, Massachusetts); Michael McKenna (Southborough, Massachusetts); Shyan-Yuan Kao (Needham, Massachusetts); Albert Edge (Brookline, Massachusetts)
ABSTRACT	Methods for treating neurodegeneration, e.g., sensorineural hearing loss, or a demyelinating disease, using bisphosphonates, ERK kinase inhibitors, and osteoprotegerin (OPG) proteins or nucleic acids.
FILED	Tuesday, March 18, 2014
APPL NO	14/218507
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/675 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 38/1793 (20130101) A61K 39/3955 (20130101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 16/2878 (20130101) C07K 2317/76 (20130101)
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09670447 — Microfabricated polymeric vessel mimetics

US 09670447	Das et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Chandan Das (Little Rock, Arkansas); Ashley A. Jaeger (North Bethesda, Maryland); Thomas J. Pohida (Monrovia, Maryland); Michael M. Gottesman (Bethesda, Maryland); Randall H. Pursley (Gaithersburg, Maryland); Philip G. McQueen (Silver Spring, Maryland); Nicole Y. Morgan (Bethesda, Maryland)
ABSTRACT	The present disclosure is directed to embodiments of microstructured membranes, methods of fabricating microstructured membranes, bioreactors housing microstructured membranes, and methods of using bioreactors and microstructured membranes. In some embodiments, the present disclosure allows culturing of cellular tissues in an environment which more accurately resembles a native environment. In some more specific embodiments, the present disclosure allows culturing of tumor cells on a membrane having a microfabricated pattern which mimics a native vasculature system.
FILED	Tuesday, January 28, 2014
APPL NO	14/166744
ART UNIT	3738 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/005 (20130101) Apparatus for Enzymology or Microbiology; C12M 25/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 2533/30 (20130101)
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09670463 — Inhibition and enhancement of reprogramming by chromatin modifying enzymes

US 09670463	Onder et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)	Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S)	Tamer T. Onder (Cambridge, Massachusetts); George Q. Daley (Weston, Massachusetts)
ABSTRACT	Methods and compositions are provided for the production of stem cells and induced pluripotent stem cells, and for uses thereof.
FILED	Sunday, October 14, 2012
APPL NO	14/351717
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 2501/065 (20130101)
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09670464 — Methods for reprogramming somatic cells

US 09670464	Jaenisch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S)	WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (Cambridge, Massachusetts)
INVENTOR(S)	Rudolf Jaenisch (Brookline, Massachusetts); Konrad Hochedlinger (Cambridge, Massachusetts)
ABSTRACT	The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
FILED	Monday, October 26, 2015
APPL NO	14/923321
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0273 (20130101) A01K 67/0275 (20130101) A01K 2217/05 (20130101) A01K 2227/105 (20130101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 15/85 (20130101) C12N 15/8509 (20130101) C12N 15/8775 (20130101) C12N 2501/603 (20130101) C12N 2506/1307 (20130101) C12N 2830/003 (20130101) C12N 2830/006 (20130101)
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09670485 — Partitioning of DNA sequencing libraries into host and microbial components

US 09670485	Bustamante et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Carlos D. Bustamante (Emerald Hills, California); Meredith L. Carpenter (San Mateo, California)
ABSTRACT	Described herein is a method for isolating microbial DNA from a sample that comprises host DNA and microbial DNA. In some embodiments, the method may comprise: obtaining a tagged DNA sample, wherein the tagged DNA sample contains host DNA and microbial DNA, both comprising an appended universal adaptor; b) hybridizing the extracted DNA, in solution, with affinity-tagged RNA probes generated by in vitro transcribing, in the presence of an affinity-tagged ribonucleotide, a library of fragmented host DNA that has been ligated to an RNA promoter adaptor; c) binding the product of step b) with a capture agent that is tethered to a substrate, in the presence of RNA oligonucleotides that are complementary to or have the same sequence as one or more strands of the universal adaptor, thereby capturing the host DNA on the substrate; and d) collecting the unbound DNA, wherein the unbound DNA comprises the microbial DNA.
FILED	Tuesday, February 10, 2015
APPL NO	14/619011
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) C12N 15/1006 (20130101) C12N 15/1013 (20130101) C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2525/191 (20130101) C12Q 2537/159 (20130101)
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09670486 — RNAi-based method of screening and characterizing drug combinations

US 09670486	Pritchard et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Justin Pritchard (Boston, Massachusetts); Douglas A. Lauffenburger (Cambridge, Massachusetts); Michael Hemann (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Justin Pritchard (Boston, Massachusetts); Douglas A. Lauffenburger (Cambridge, Massachusetts); Michael Hemann (Cambridge, Massachusetts)
ABSTRACT	In one aspect, the invention is directed to a method of characterizing a mechanism of action of a combination of agents. The method comprises contacting a plurality of populations of cells with a combination of agents to be assessed, wherein each population of cells have one gene of interest targeted by a small hairpin RNA (shRNA) and wherein the gene of interest regulates cell death and a plurality of genes that regulate cell death are targeted in the plurality of populations of cells. A responsiveness of each population of cells to the combination of agents is determined, thereby obtaining an shRNA signature of the combination of agents so as to identify one or more genes that mediate a response to the combination of agents, thereby characterizing the mechanism of action of the combination of agents. In another aspect, the invention is directed to a method of determining whether a patient population treated with a first agent would benefit from a treatment using the first agent in combination with one or more additional agents. In yet another aspect, the invention is directed to method of determining whether a formulation of one or more agents maintains a mechanism of action of the one or more agents when unformulated.
FILED	Friday, December 16, 2011
APPL NO	13/994057
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1079 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101)
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09670495 — Pan-yeast autonomously replicating sequence

US 09670495	Dunham et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
ASSIGNEE(S)	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
INVENTOR(S)	Maitreya Dunham (Seattle, Washington); Ivan Liachko (Seattle, Washington)
ABSTRACT	A DNA sequence that functions as an origin in many different yeast species. From 1 to 17 mutations can be introduced into this sequence to improve its function across multiple yeasts. The resulting synthetic DNA sequence confers stable plasmid replication function in all yeast species tested, including but not limited to Saccharomyces cerevisiae, Lachancea kluyveri, Kluyveromyces lactis, Kluyveromyces wickerhammii, Hansenula polymorpha, and Pichia pastoris. Also provided are sequences that function as an optimal origin in the industrially useful Pichia pastoris.
FILED	Tuesday, February 25, 2014
APPL NO	14/770074
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/69 (20130101) C12N 15/81 (20130101) Original (OR) Class C12N 15/815 (20130101)
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09670507 — Directed evolution and in vivo panning of virus vectors

US 09670507	Xiao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Xiao Xiao (Chapel Hill, North Carolina); Lin Yang (Chapel Hill, North Carolina)
ABSTRACT	The present invention provides methods of achieving directed evolution of viruses by in vivo screening or “panning” to identify viruses comprising scrambled AAV capsids having characteristics of interest, e.g., tropism profile and/or neutralization profile (e.g., ability to evade neutralizing antibodies). The invention also provides scrambled AAV capsids and virus particles comprising the same.
FILED	Tuesday, June 28, 2016
APPL NO	15/195035
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) A61K 38/00 (20130101) A61K 38/1719 (20130101) A61K 48/0058 (20130101) Peptides C07K 14/005 (20130101) C07K 14/705 (20130101) C07K 14/4716 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14151 (20130101)
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09670527 — Enrichment of nucleic acids by complimentary capture

US 09670527	Vogelstein et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Bert Vogelstein (Balitmore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Jian Wu (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Bert Vogelstein (Balitmore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Jian Wu (Baltimore, Maryland)
ABSTRACT	Assays can be used to detect mutations found in neoplasms of the pancreas, as well as for other neoplasms and other uses. Nucleic acids can be captured from body fluids such as cyst fluids. Thousands of oligonucleotides can be synthesized in parallel, amplified and ligated together. The ligated products can be further amplified. The amplified, ligated products are used to capture complementary DNA sequences, which can be analyzed, for example by massively parallel sequencing.
FILED	Thursday, June 28, 2012
APPL NO	14/130007
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 2535/122 (20130101) C12Q 2563/131 (20130101) C12Q 2563/149 (20130101) C12Q 2565/518 (20130101)
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09670539 — Synthesis of cleavable fluorescent nucleotides as reversible terminators for DNA sequencing by synthesis

US 09670539	Ju et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Jingyue Ju (Englewood Cliffs, New Jersey); Huanyan Cao (Changzhou, China PRC); Zengmin Li (New York, New York); Qinglin Meng (Foster City, California); Jia Guo (Chandler, Arizona); Shenglong Zhang (Fort Lee, New Jersey); Lin Yu (New York, New York)
ABSTRACT	This invention provides novel azido linkers for deoxynucleotide analogs having a detectable marker attached thereto.
FILED	Monday, September 21, 2015
APPL NO	14/859853
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/06 (20130101) C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 19/16 (20130101) C07H 19/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2525/301 (20130101) C12Q 2537/157 (20130101)
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09670540 — Methods and devices for DNA sequencing and molecular diagnostics

US 09670540	Barany et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Francis A. Barany (New York, New York); Steven A. Soper (Baton Rouge, Louisiana); George Grills (Trumansburg, New York); Yu-wei Cheng (Beachwood, Ohio); Jianmin Huang (Elmhurst, New York); Hong Wang (Mesa, Arizona); Malgorzata A. Witek (Chapel Hill, North Carolina); Daniel Sang-won Park (Baton Rouge, Louisiana); Michael C. Murphy (Baton Rouge, Louisiana); Robin Lindsey McCarley (Prairieville, Louisiana); Mateusz L. Hupert (Chapel Hill, North Carolina)
ASSIGNEE(S)	Cornell University (Ithaca, New York); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Francis A. Barany (New York, New York); Steven A. Soper (Baton Rouge, Louisiana); George Grills (Trumansburg, New York); Yu-wei Cheng (Beachwood, Ohio); Jianmin Huang (Elmhurst, New York); Hong Wang (Mesa, Arizona); Malgorzata A. Witek (Chapel Hill, North Carolina); Daniel Sang-won Park (Baton Rouge, Louisiana); Michael C. Murphy (Baton Rouge, Louisiana); Robin Lindsey McCarley (Prairieville, Louisiana); Mateusz L. Hupert (Chapel Hill, North Carolina)
ABSTRACT	The present invention is directed to methods for capturing, amplifying and identifying one or more of a plurality of target nucleotide sequences in a sample. The present invention is further directed to a device comprising a solid support having a plurality of wells or pillars and a plurality of oligonucleotides attached to the wells or pillars. Other aspects of the invention are directed to methods of making such devices.
FILED	Monday, July 23, 2012
APPL NO	14/234011
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/197 (20130101) C12Q 2525/313 (20130101) C12Q 2535/122 (20130101) C12Q 2563/131 (20130101) C12Q 2565/543 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/585 (20130101)
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09670543 — Detection and treatment of polycystic kidney disease

US 09670543	Germino et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Johns Hopkins University School of Medicine (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University School of Medicine (Baltimore, Maryland)
INVENTOR(S)	Gregory G. Germino (Chevy Chase, Maryland); Terry J. Watnick (Chevy Chase, Maryland); Bunyong Phakdeekitcharoen (Bangkok, Thailand)
ABSTRACT	Compositions useful for examining the PKD1 gene are provided. In addition, methods for detecting mutations of the PKD1 gene, which can be associated with autosomal dominant polycystic kidney disease in humans, are provided. Methods for diagnosing a mutant PKD1 gene sequence in a subject also are provided, as are methods of treating a subject having a PKD1-associated disorder.
FILED	Monday, August 12, 2013
APPL NO	13/965083
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101)
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09670548 — Methods of diagnosing colorectal cancer by detecting FADA expression

US 09670548	Han
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Yiping Han (Beachwood, Ohio)
ABSTRACT	A method of identifying a subject with increased risk of colorectal cancer includes obtaining a biological sample from the subject, measuring the level of Fusobacterium nucleatum in the biological sample, and comparing the measured level to a control level, wherein an increased measured level compared to the control level is indicative of increased risk of colorectal cancer in the subject.
FILED	Friday, January 24, 2014
APPL NO	14/163395
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101)
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09670549 — Gene expression signatures of neoplasm responsiveness to therapy

US 09670549	Mock et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) U.S. Public Health Service (USPHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Beverly A. Mock (Bethesda, Maryland); John K. Simmons (Washington, District of Columbia); Aleksandra Michalowski (Middletown, Maryland); Jyoti Patel (Germantown, Maryland)
ABSTRACT	Gene signatures for determining whether a neoplasm (such as a multiple myeloma neoplasm) is sensitive to mTORi/HDACi combination therapy and/or for determining the prognosis of a neoplasm in a subject are described. Some embodiments include determining whether a neoplasm is sensitive to mTORi/HDACi combination therapy by predicting whether mTORi/HDACi combination therapy will successfully treat the neoplasm, for example increasing survival of the subject with the neoplasm. In some embodiments, determining the prognosis includes predicting the outcome (such as chance of survival) of the subject with a neoplasm. Also disclosed are reagents, for example arrays, for use with the disclosed methods, as well as computer implementation of the disclosed methods.
FILED	Monday, November 12, 2012
APPL NO	14/357191
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 31/4045 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2800/52 (20130101) Electric Digital Data Processing G06F 19/20 (20130101)
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09671391 — IL-34 receptor assays and uses thereof

US 09671391	Stanely et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Center for Research Resources (NCRR)
APPLICANT(S)	ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York)
ASSIGNEE(S)	ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York)
INVENTOR(S)	Evan Richard Stanely (New York, New York); Sayan Nandi (Bronx, New York); Yee-Guide Yeung (Hartsdale, New York)
ABSTRACT	Methods are disclosed for identifying activators and inhibitors of actions of interleukin-34 (IL-34) that are independent of the colony stimulating factor-1 (CSF-1) receptor (CSF-1R) and play a role in development, homeostasis and disease.
FILED	Monday, May 19, 2014
APPL NO	14/891405
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/244 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5058 (20130101) Original (OR) Class G01N 2333/916 (20130101)
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09671403 — Biosensor for detecting multiple epitopes on a target

US 09671403	Heyduk et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Saint Louis University (St. Louis, Missouri); Mediomics LLC (St. Louis, Missouri)
ASSIGNEE(S)	MEDIOMICS, LLC (St. Louis, Missouri); SAINT LOUIS UNIVERSITY (St. Louis, Missouri)
INVENTOR(S)	Tomasz Heyduk (Ballwin, Missouri); Ling Tian (St. Louis, Missouri)
ABSTRACT	The present invention encompasses a method for detecting a target comprising a repeating epitope.
FILED	Monday, March 30, 2015
APPL NO	14/673336
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/56916 (20130101) Original (OR) Class G01N 2333/245 (20130101) G01N 2333/255 (20130101)
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09671405 — Identifying taxane sensitivity in prostate cancer patients

US 09671405	Giannakakou et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Cornell University (Ithaca, New York); University of Washington (Seattle, Washington)
ASSIGNEE(S)	Cornell University (Ithaca, New York); University of Washington (Seattle, Washington)
INVENTOR(S)	Paraskevi Giannakakou (Tenafly, New Jersey); Stephen R. Plymate (Seattle, Washington)
ABSTRACT	The invention relates to detection and/or treatment of a subset of prostate cancer patients who may benefit from taxane treatment. The method comprises testing whether an androgen receptor (AR) splice variant is present in a test sample obtained from the patient, wherein the androgen receptor variant can be ARv5,6,7.
FILED	Thursday, September 19, 2013
APPL NO	14/429657
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 2333/723 (20130101)
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09671412 — Beclin 1 phosphorylation

US 09671412	Levine et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Beth C. Levine (Dallas, Texas); Richard C. Wang (Dallas, Texas); Yongjie Wei (Dallas, Texas)
ABSTRACT	Antibodies specific for human Beclin 1 protein phosphorylated Ser234, Ser295, Tyr229, Tyr233 or Try352 are useful in diagnosing diseases such as cancer and impaired autophagy. The invention further relates to human Beclin 1 mutated at Ser234, Ser295, Tyr229, Tyr233 or Try352 with a phospho-silencing residue and uses thereof.
FILED	Tuesday, March 24, 2015
APPL NO	14/667372
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/82 (20130101) C07K 14/4702 (20130101) C07K 16/18 (20130101) C07K 16/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) Original (OR) Class G01N 33/57484 (20130101) G01N 2440/14 (20130101) G01N 2800/52 (20130101)
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09671414 — Assays and methods of treatment relating to vitamin D insufficiency

US 09671414	Thadhani et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Ravi Thadhani (Boston, Massachusetts); S. Ananth Karumanchi (Chestnut Hill, Massachusetts); Anders Hayden Berg (Dedham, Massachusetts); Ishir Bhan (West Newton, Massachusetts)
ABSTRACT	Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.
FILED	Friday, May 02, 2014
APPL NO	14/888765
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/592 (20130101) A61K 31/593 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/82 (20130101) Original (OR) Class G01N 2333/765 (20130101)
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09671481 — Method for reducing power deposition in magnetic resonance imaging using multiband pulses and multichannel transmission

US 09671481	Ugurbil
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of Mental Health (NIMH)
APPLICANT(S)	Kamil Ugurbil (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Kamil Ugurbil (Minneapolis, Minnesota)
ABSTRACT	A method is provided for substantially simultaneously manipulating spins in a plurality of slice locations using a magnetic resonance imaging (“MRI”) system that includes a radio frequency (“RF”) coil array composed of a plurality of RF coil elements, and in which power deposition, which may be measured as specific absorption rate (“SAR”), is reduce A plurality of slice locations to be substantially simultaneously manipulated with the MRI system are selected, and an RF transmission map (B₁⁺map) is provided for each of the plurality of RF coil elements. A subset of slice locations to be manipulated by each of the RF coil elements is then selected using the provided RF transmission maps. Using the selected subsets of slice locations, an RF pulse to be transmitted by each of the RF coil elements is designed. The designed RF pulses are then substantially simultaneously transmitted by the MRI system to substantially simultaneously manipulate spins in each o the plurality of slice locations.
FILED	Tuesday, December 20, 2011
APPL NO	13/995875
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/543 (20130101) Original (OR) Class G01R 33/3415 (20130101) G01R 33/4835 (20130101) G01R 33/5612 (20130101)
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09672631 — Medical image reporting system and method

US 09672631	Higgins et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	William E. Higgins (State College, Pennsylvania); Jason D. Gibbs (State College, Pennsylvania); Kun-Chang Yu (State College, Pennsylvania); Michael W. Graham (State College, Pennsylvania); Kongkuo Lu (State College, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	William E. Higgins (State College, Pennsylvania); Jason D. Gibbs (State College, Pennsylvania); Kun-Chang Yu (State College, Pennsylvania); Michael W. Graham (State College, Pennsylvania); Kongkuo Lu (State College, Pennsylvania)
ABSTRACT	This invention relates generally to medical imaging and, in particular, to a method and system for reconstructing a model path through a branched tubular organ. Novel methodologies and systems segment and define accurate endoluminal surfaces in airway trees, including small peripheral bronchi. An automatic algorithm is described that searches the entire lung volume for airway branches and poses airway-tree segmentation as a global graph-theoretic optimization problem. A suite of interactive segmentation tools for cleaning and extending critical areas of the automatically segmented result is disclosed. A model path is reconstructed through the airway tree.
FILED	Monday, February 16, 2009
APPL NO	12/866758
ART UNIT	3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/12 (20170101) G06T 7/162 (20170101) Original (OR) Class G06T 2207/20044 (20130101) G06T 2207/30061 (20130101)
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09672788 — Reducing visual crowding, increasing attention and improving visual span

US 09672788	Rosen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S)	Sarah Rosen (Hoboken, New Jersey); Denis G. Pelli (New York, New York)
ABSTRACT	Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for modifying displayed text in a gaze-contingent way to reduce crowding, thus increasing the observer's visual span, and thus increasing the observer's reading rate. The trick is to introduce only a few differences between characters (not enough to produce a pattern) of text so as to reduce crowding. For example, differences between characters near the left and right extremes of the observer's estimated visual span can be altered to reduce crowding.
FILED	Friday, October 19, 2012
APPL NO	14/352869
ART UNIT	2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Electric Digital Data Processing G06F 3/013 (20130101) G06F 17/214 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0061 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 2207/10048 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/02 (20130101) Original (OR) Class G09G 5/26 (20130101) G09G 2320/0666 (20130101) G09G 2354/00 (20130101)
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09673030 — Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry

US 09673030	Jones et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)	Dean P. Jones (Decatur, Georgia); Quinlyn A. Soltow (Atlanta, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia)
INVENTOR(S)	Dean P. Jones (Decatur, Georgia); Quinlyn A. Soltow (Atlanta, Georgia)
ABSTRACT	Described herein are computer-readable storage mediums, methods and systems useful for analyzing samples via mass spectrometry. Aspects described herein include methods for normalizing mass spectrometry data that include providing a reference set of mass spectrometry data obtained from a first external standard sample having one or more isotopic standards, wherein the reference set of mass spectrometry data comprises one or more m/z intensity ratios. Methods described herein are useful for reducing errors based on instrument response and ionization efficiencies and improve reproducibility of data from instrument to instrument and from day to day.
FILED	Tuesday, May 17, 2011
APPL NO	13/109642
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Electric Digital Data Processing G06F 17/10 (20130101) G06F 19/12 (20130101) G06F 19/24 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0009 (20130101) Original (OR) Class H01J 49/0036 (20130101)
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RE046423 — Compositions of engineered human arginases and methods for treating cancer

US RE46423	Georgiou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	AERASE, INC. (Austin, Texas)
ASSIGNEE(S)	AERASE, INC. (Austin, Texas)
INVENTOR(S)	George Georgiou (Austin, Texas); Everett Stone (Austin, Texas)
ABSTRACT	Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise deficient in, argininosuccinate synthetase, with enzymes that deplete L-Arginine in serum. In one embodiment, the present invention contemplates an arginase protein, such as a human Arginase I protein, comprising at least one amino acid substitution and a metal cofactor, said protein comprising an increased catalytic activity when compared with a native human Arginase I.
FILED	Thursday, May 14, 2015
APPL NO	14/711916
ART UNIT	3991 — Central Reexamination Unit (Chemical)
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/50 (20130101) Original (OR) Class A61K 47/48215 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) Enzymes C12Y 305/03001 (20130101)
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Department of Defense (DOD)

09668652 — System, apparatus and method for utilizing optical dispersion for fourier-domain optical coherence tomography

US 09668652	Vakoc et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Benjamin Vakoc (Arlington, Massachusetts); Meena Siddiqui (Boston, Massachusetts); Serhat Tozburun (Malden, Massachusetts)
ABSTRACT	An apparatus can be provided which can include a laser arrangement which can be configured to provide a laser radiation, and can include an optical cavity. The optical cavity can include a dispersive optical first arrangement which can be configured to receive and disperse at least one first electro-magnetic radiation so as to provide at least one second electro-magnetic radiation. Such cavity can also include an active optical modulator second arrangement which can be configured to receive and modulate the at least one second radiation so as to provide at least one third electro-magnetic radiation. The optical cavity can further include a dispersive optical third arrangement which can be configured to receive and disperse at least one third electro-magnetic radiation so as to provide at least one fourth electro-magnetic radiation. For example, actions by the first, second and third arrangements can cause a spectral filtering of the fourth electro-magnetic radiation(s) relative to the first electro-magnetic radiation(s). The laser radiation can be associated with the fourth radiation(s), and a wavelength of the laser radiation can be controlled by the spectral filtering caused by the actions by the first, second and third arrangements.
FILED	Friday, July 25, 2014
APPL NO	14/907028
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Original (OR) Class A61B 5/0075 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02007 (20130101) G01B 9/02008 (20130101) G01B 9/02014 (20130101) G01B 9/02044 (20130101) G01B 9/02091 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1062 (20130101) H01S 3/08004 (20130101)
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09668689 — Event dosimeter device and methods thereof

US 09668689	Borkholder et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	David A. Borkholder (Canandaigua, New York); Gregory T. A. Kovacs (Palo Alto, California); Jeffrey Rogers (Alexandria, Virginia)
ASSIGNEE(S)	Rochester Institute of Technology (Rochester, New York); Defense Advanced Research Projects Agency (Arlington, Virginia)
INVENTOR(S)	David A. Borkholder (Canandaigua, New York); Gregory T. A. Kovacs (Palo Alto, California); Jeffrey Rogers (Alexandria, Virginia)
ABSTRACT	A method including a dosimetry device having at least one sensor in a housing and a dosimetry processing device with a memory. The dosimtery processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the sensor; storing the readings; conducting an analysis of the stored readings to determine an injury risk assessment; and outputting at least one of the conducted analysis of the determined injury risk assessment or the stored readings.
FILED	Friday, April 15, 2016
APPL NO	15/130074
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/1112 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/6803 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 1/02 (20130101) F41H 1/04 (20130101) Blasting F42D 5/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115)
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09668846 — Textile-templated electrospun anisotropic scaffolds for tissue engineering and regenerative medicine

US 09668846	Lelkes et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Natick Soldier Systems Center (NSSC)
APPLICANT(S)	Peter I. Lelkes (Cherry Hill, New Jersey); H. Gozde Senel (Philadelphia, Pennsylvania); David Brookstein (Fort Washington, Pennsylvania); Muthu Govindaraj (Harleysville, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania); Philadelphia University (Philadelphia, Pennsylvania)
INVENTOR(S)	Peter I. Lelkes (Cherry Hill, New Jersey); H. Gozde Senel (Philadelphia, Pennsylvania); David Brookstein (Fort Washington, Pennsylvania); Muthu Govindaraj (Harleysville, Pennsylvania)
ABSTRACT	The present invention includes an anisotropic scaffold, which is prepared by electrospinning a solution of matrix material upon a textile template. The present invention further includes a method of preparing such scaffold. The anisotropic scaffold of the invention finds use in tissue engineering and regenerative medicine.
FILED	Monday, May 23, 2011
APPL NO	13/699442
ART UNIT	1676 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0063 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/3826 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 89/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/08 (20130101)
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09668889 — Percutaneous osseointegrated prosthetic implant system

US 09668889	Holt et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Brian Mueller Holt (Topanga, California); Kent N. Bachus (Salt Lake City, Utah); Sujee Jeyapalina (Salt Lake City, Utah); James Peter Beck (Salt Lake City, Utah); Roy Bloebaum (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Brian Mueller Holt (Topanga, California); Kent N. Bachus (Salt Lake City, Utah); Sujee Jeyapalina (Salt Lake City, Utah); James Peter Beck (Salt Lake City, Utah); Roy Bloebaum (Salt Lake City, Utah)
ABSTRACT	An implant system for securing a prosthesis to a selected bone of a subject including a stem and an abutment. The stem includes a porous region that promotes osseointegration of the selected bone following implantation of the stem. The abutment is secured to the stem and is configured for secure attachment to the prosthesis. The stem and the abutment include ultra-low friction and/or highly polished surfaces at select locations that inhibit bio-adhesion.
FILED	Wednesday, June 06, 2012
APPL NO	14/123719
ART UNIT	3738 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 2008/0046 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/78 (20130101) Original (OR) Class A61F 2/2814 (20130101) A61F 2002/3694 (20130101) A61F 2002/7887 (20130101) A61F 2002/30013 (20130101) A61F 2002/30332 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2270/0421 (20130101)
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09669098 — Metal-organic frameworks with exceptionally large pore aperatures

US 09669098	Yaghi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Energy (DOE)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Omar M. Yaghi (Berkeley, California); Hiroyasu Furukawa (Berkeley, California); Hexiang Deng (Albany, California)
ABSTRACT	The disclosure relates to metal organic frameworks or isoreticular metal organic frameworks, methods of production thereof, and methods of use thereof.
FILED	Monday, July 13, 2015
APPL NO	14/797312
ART UNIT	1671 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/24 (20130101) Original (OR) Class Separation B01D 53/02 (20130101) B01D 2253/204 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0225 (20130101) B01J 20/226 (20130101) B01J 20/28016 (20130101) B01J 20/28066 (20130101) B01J 20/28073 (20130101) B01J 20/28076 (20130101) B01J 2220/58 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/02 (20130101) C07F 3/06 (20130101) C07F 5/025 (20130101) C07F 7/2224 (20130101) Peptides C07K 14/435 (20130101)
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09669232 — Method for non-invasive brain stimulation

US 09669232	Khizroev et al.
FUNDED BY	Department of Defense (DOD) Defense MicroElectronics Activity (DMEA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF)
APPLICANT(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S)	Sakhrat Khizroev (Coral Gables, Florida); Madhavan P. N. Nair (Coral Gables, Florida)
ABSTRACT	Magneto-electric nanoparticles in a subject interact with an external magnetic field to cause stimulation of neural networks in the subject. Electric signals in the neural network are coupled to magnetic dipoles induced in the nanoparticles to cause changes in electric pulse sequences of the subject's brain.
FILED	Thursday, February 04, 2016
APPL NO	15/015760
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/40 (20130101) A61N 2/02 (20130101) A61N 2/006 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0045 (20130101)
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09669416 — Electrospraying systems and associated methods

US 09669416	Velásquez-García et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Luis Fernando Velásquez-García (Newton, Massachusetts); Frances Ann Hill (Cambridge, Massachusetts); Philip James Ponce De Leon (Shenorock, New York)
ABSTRACT	Electrospraying systems and associated methods are generally described.
FILED	Friday, June 14, 2013
APPL NO	13/918742
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/14 (20130101) B05B 5/025 (20130101) B05B 5/0255 (20130101) Original (OR) Class B05B 5/0536 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/007 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0069 (20130101)
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09669539 — Magnetic drill system

US 09669539	Scheid et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Eric Scheid (Bloomington, Indiana); Brad Moan (Greenwood, Indiana); Travis Bohnert (Raeford, North Carolina)
ABSTRACT	An auto-feeding permanent magnet drill comprising a first permanent magnet capable of being removeably coupled to a magnetic material. A coupler plate couples to the first permanent magnet. A drill frame couples to the coupler plate, the coupler plate providing an interface to couple the first permanent magnet to the frame. User interfaces are provided to enable control for powering the drill, enabling a drill or cutter bit auto-feed feature, enabling a lubrication system and enabling a mechanical adjustment system. An electric drill is coupled to the frame, the electric drill coupled to the auto-feed feature and electronically coupled to the user interfaces. A lubrication reservoir couples to a second permanent magnet capable of coupling the lubrication reservoir to a magnetic material or work surface. A flexible distribution tube delivers lubricant from the lubrication reservoir to a nozzle, the nozzle oriented towards the cutting surface and capable of distributing lubricating fluid to the cutting surface or rotating drill bit components during a drilling operation.
FILED	Monday, March 23, 2015
APPL NO	14/666269
ART UNIT	3722 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Turning; Boring B23B 45/02 (20130101) B23B 2250/12 (20130101) B23B 2260/122 (20130101) B23B 2260/128 (20130101) B23B 2270/32 (20130101) B23B 2270/483 (20130101) Details, Components, or Accessories for Machine Tools, e.g Arrangements for Copying or Controlling; Machine Tools in General Characterised by the Construction of Particular Details or Components; Combinations or Associations of Metal-working Machines, Not Directed to a Particular Result B23Q 9/00 (20130101) B23Q 11/10 (20130101) B23Q 11/1092 (20130101) Workshop Equipment, e.g for Marking-out Work; Storage Means for Workshops B25H 1/0071 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 408/03 (20150115) Y10T 408/16 (20150115) Y10T 408/44 (20150115) Y10T 408/46 (20150115) Y10T 408/172 (20150115) Y10T 408/554 (20150115)
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09669599 — Galvanic-corrosion-resistant composite material having a self-extingushing barrier layer

US 09669599	Tsang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The Government of The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The Government of the United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Joseph W. Tsang (Ridgecrest, California); Raymond J. Meilunas (Lexington Park, Maryland); Benjamin Harvey (Ridgecrest, California); Matthew Davis (Ridgecrest, California)
ABSTRACT	A composite material composition that is simultaneously resistant to fire and galvanic corrosion; and, a method of manufacturing a composite material that has a fire resistant polycyuranate outermost barrier layer in composite structures.
FILED	Thursday, January 29, 2015
APPL NO	14/121015
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/22 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/31547 (20150401)
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09669925 — Air vehicle flight mechanism and control method for non-sinusoidal wing flapping

US 09669925	Keennon et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	AeroVironment, Inc. (Monrovia, California)
ASSIGNEE(S)	AEROVIRONMENT, INC. (Monrovia, California)
INVENTOR(S)	Matthew Todd Keennon (Simi Valley, California); Alexander Andryukov (Simi Valley, California); Karl Robert Klingebiel (Simi Valley, California); Henry Thome Won (Sherman Oaks, California)
ABSTRACT	A flapping wing driving apparatus includes at least one crank gear capstan rotatably coupled to a crank gear, the at least one crank gear capstan disposed radially offset from a center of rotation of the crank gear; a first wing capstan coupled to a first wing, the first wing capstan having a first variable-radius drive pulley portion; and a first drive linking member configured to drive the first wing capstan, the first drive linking member windably coupled between the first variable-radius drive pulley portion and one of the at least one crank gear capstan; wherein the first wing capstan is configured to non-constantly, angularly rotate responsive to a constant angular rotation of the crank gear.
FILED	Friday, August 16, 2013
APPL NO	13/969258
ART UNIT	3634 — Static Structures, Supports and Furniture
CURRENT CPC	Aeroplanes; Helicopters B64C 33/02 (20130101) B64C 39/003 (20130101) Original (OR) Class B64C 39/028 (20130101) B64C 2201/025 (20130101) B64C 2201/042 (20130101)
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09670066 — Carbon particles

US 09670066	Lipka et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Stephen M. Lipka (Nicholasville, Kentucky); Christopher R. Swartz (Lexington, Kentucky)
ASSIGNEE(S)	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S)	Stephen M. Lipka (Nicholasville, Kentucky); Christopher R. Swartz (Lexington, Kentucky)
ABSTRACT	A composition generally includes carbon particles. The particles are prepared by dissolving a carbohydrate-based precursor in water to form a precursor solution and placing the precursor solution in a pressure vessel. The precursor solution is placed in a pressure vessel. The pressure vessel is heated to a reaction temperature to form carbon particles. The carbon particles are subjected to a chemical activation and a physical activation. The composition includes, by weight, about 5% to about 30% oxygen.
FILED	Friday, November 22, 2013
APPL NO	14/087219
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 31/02 (20130101) C01B 31/08 (20130101) Original (OR) Class C01B 31/10 (20130101) C01B 31/12 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/34 (20130101) H01G 11/42 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) Y10T 428/2982 (20150115)
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09670317 — Hydrophobic polymer for water proofing, anti-corrosion, and anti-fouling applications

US 09670317	Lai et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	William W. Lai (Ridgecrest, California); Benjamin G. Harvey (Ridgecrest, California); Alfred J. Baca (Ridgecrest, California); Heather Meylemans (Ridgecrest, California)
ABSTRACT	A material that can be used either as a standalone or coating additive that would both repel water and resist corrosion would greatly benefit the Navy. A method of making hydrophobic polymer, including combining a perylene derived monomer with a bisphenol derived monomer to produce a polymer mixture, and condensing said polymer mixture to produce a hydrophobic polymer.
FILED	Tuesday, March 29, 2016
APPL NO	15/084239
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/40 (20130101) Original (OR) Class C08G 2150/90 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/08 (20130101) C09D 5/1662 (20130101) C09D 171/00 (20130101)
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09670589 — Alkali uranium fluorophosphate-based crystals and methods of fabrication

US 09670589	Mann et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	James M Mann (Springboro, Ohio); Eric Hunt (Glen Rock, Pennsylvania)
ABSTRACT	A method of synthesizing alkali uranium fluorophosphate crystals. The method includes combining a uranium-based feedstock with a mineralizer solution. The mineralizer solution includes an alkali nutrient, a phosphate, and a fluoride. The feedstock and mineralizer solution are pressurized and a thermal gradient applied thereto such that a first portion of the feedstock and the mineralizer solution is heated to a temperature that is greater than a temperature of a second portion of the feedstock and the mineralizer solution. Uranium nutrient enters the mineralizer solution from the feedstock in the first portion and uranium nutrient precipitates to spontaneously form crystals in the second portion.
FILED	Tuesday, March 22, 2016
APPL NO	15/077347
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 25/45 (20130101) C01B 25/455 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/006 (20130101) C01G 43/06 (20130101) C01G 43/025 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/76 (20130101) C01P 2002/77 (20130101) C01P 2006/60 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7709 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/10 (20130101) Original (OR) Class C30B 7/14 (20130101) C30B 29/12 (20130101) C30B 29/14 (20130101) C30B 29/16 (20130101)
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09670781 — Gas turbine engines with turbine rotor blades having improved platform edges

US 09670781	Halfmann et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	HONEYWELL INTERNATIONAL INC. (Morristown, New Jersey)
ASSIGNEE(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
INVENTOR(S)	Steve Halfmann (Chandler, Arizona); Mark C. Morris (Phoenix, Arizona); Jason Smoke (Phoenix, Arizona); Brandan Wakefield (Phoenix, Arizona); Bob Mitlin (Scottsdale, Arizona)
ABSTRACT	A turbine rotor blade is provided. The turbine rotor blade includes a root, a platform coupled to the root, and an airfoil extending from the platform. The platform has a leading edge, a trailing edge, a suction side edge, and a pressure side edge. The pressure side edge includes a first concave portion.
FILED	Tuesday, September 17, 2013
APPL NO	14/028734
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) Original (OR) Class F01D 5/22 (20130101) F01D 5/141 (20130101) F01D 5/3007 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/80 (20130101) F05D 2250/75 (20130101) F05D 2250/184 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49336 (20150115)
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09671216 — Modulated laser for atom interferometers

US 09671216	Narducci et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Francesco Narducci (Dowell, Maryland); Brandi Gerstner (Lexington Park, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Francesco Narducci (Dowell, Maryland); Brandi Gerstner (Lexington Park, Maryland)
ABSTRACT	The present invention is directed to a modulated which includes a semiconductor laser being driven by direct current for frequency tuning, and an AC current with two radio frequencies that can generate repump and Raman frequencies, such that only one laser is needed to produce all the frequencies required to operate an atom interferometer. The present invention is also directed to a method of double modulating a laser to produce all required frequencies for an atom interferometer.
FILED	Monday, February 08, 2016
APPL NO	15/017829
ART UNIT	2881 — Optics
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02007 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/042 (20130101) H01S 5/0078 (20130101) H01S 5/0687 (20130101)
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09671224 — Methods resolving the elevation of a tracked personnel or assets

US 09671224	Karvounis et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	TRX Systems, Inc. (Greenbelt, Maryland)
ASSIGNEE(S)	TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S)	John Karvounis (Bowie, Maryland); Jared Napora (Severn, Maryland); Benjamin E. Funk (Hanover, Maryland); Dan Hakim (Silver Spring, Maryland); Christopher Giles (Elkton, Maryland); Carole Teolis (Glenn Dale, Maryland)
ABSTRACT	Methods and systems are described for determining the elevation of tracked personnel or assets (trackees) that can take input from mounted sensors on each trackee (including barometric, inertial, magnetometer, radio frequency ranging and signal strength, light and GPS sensors), external constraints (including ranging constraints, feature constraints, and user corrections), and terrain elevation data. An example implementation of this method for determining elevation of persons on foot is described. But this method is not limited to computing elevation of personnel or to on foot movements.
FILED	Wednesday, June 12, 2013
APPL NO	13/916024
ART UNIT	2853 — Printing/Measuring and Testing
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 5/00 (20130101) Original (OR) Class G01C 5/06 (20130101) G01C 21/206 (20130101)
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09671301 — Small-scale pressure sensors

US 09671301	Carroll et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	David L. Carroll (Winston-Salem, North Carolina); Faith M. Coldren (Strasbourg, France); Nicole H. Levi (Winston-Salem, North Carolina); Lawrence X. Webb (Winston-Salem, North Carolina); William D. Wagner (Clemmons, North Carolina); Thomas L. Smith (Winston-Salem, North Carolina); Brian Werner (Lancaster, Pennsylvania); J. Baxter Mcguirt (Winston-Salem, North Carolina); Manoj Namboothiry (West Lafayette, Indiana)
ASSIGNEE(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S)	David L. Carroll (Winston-Salem, North Carolina); Faith M. Coldren (Strasbourg, France); Nicole H. Levi (Winston-Salem, North Carolina); Lawrence X. Webb (Winston-Salem, North Carolina); William D. Wagner (Clemmons, North Carolina); Thomas L. Smith (Winston-Salem, North Carolina); Brian Werner (Lancaster, Pennsylvania); J. Baxter Mcguirt (Winston-Salem, North Carolina); Manoj Namboothiry (West Lafayette, Indiana)
ABSTRACT	The present invention provides a method of sensing pressure in a region of interest by providing a plurality of metallic particles operatively associated with one another in the region of interest (for example, wherein the metallic particles sustain a plasmon upon excitation), and with the metallic particles configured or positioned in relationship to one another so that a physical property of the particles (for example, the energy of the plasmon) varies in response to pressure; measuring the physical property of the metallic particles that varies in response to pressure; and then determining the pressure in the region of interest from the detected physical property (e.g., resistance, energy of the plasmon). Compositions, articles and formulations for carrying out the method in industrial and biomedical applications are also described.
FILED	Friday, September 28, 2007
APPL NO	12/443249
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/03 (20130101) A61B 5/445 (20130101) A61B 2562/0247 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 11/02 (20130101) Original (OR) Class
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09671362 — ph sensor with bonding agent disposed in a pattern

US 09671362	Horkheimer et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Honeywell International Inc. (Morristown, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Donald Horkheimer (Minneapolis, Minnesota); Paul S. Fechner (Plymouth, Minnesota); David S. Willits (Long Lake, Minnesota)
ABSTRACT	Embodiments described herein provide for a pH sensor that comprises a substrate and an ion sensitive field effect transistor (ISFET) die. The ISFET die includes an ion sensing part that is configured to be exposed to a medium such that it outputs a signal related to the pH level of the medium. The ISFET die is bonded to the substrate with at least one composition of bonding agent material disposed between the ISFET die and the substrate. One or more strips of the at least one composition of bonding agent material is disposed between the substrate and the ISFET die in a first pattern.
FILED	Monday, July 29, 2013
APPL NO	13/952879
ART UNIT	2896 — Optics
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/1292 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 27/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/414 (20130101) Original (OR) Class G01N 27/4148 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/33 (20130101) H01L 24/83 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/35 (20130101) H01L 2924/01322 (20130101) H01L 2924/01322 (20130101) H01L 2924/12042 (20130101) H01L 2924/12042 (20130101)
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09671405 — Identifying taxane sensitivity in prostate cancer patients

US 09671405	Giannakakou et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Cornell University (Ithaca, New York); University of Washington (Seattle, Washington)
ASSIGNEE(S)	Cornell University (Ithaca, New York); University of Washington (Seattle, Washington)
INVENTOR(S)	Paraskevi Giannakakou (Tenafly, New Jersey); Stephen R. Plymate (Seattle, Washington)
ABSTRACT	The invention relates to detection and/or treatment of a subset of prostate cancer patients who may benefit from taxane treatment. The method comprises testing whether an androgen receptor (AR) splice variant is present in a test sample obtained from the patient, wherein the androgen receptor variant can be ARv5,6,7.
FILED	Thursday, September 19, 2013
APPL NO	14/429657
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 2333/723 (20130101)
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09671443 — Device and method for measuring static charge on flying insects

US 09671443	Bertrand
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Jacques C. Bertrand (Gainesville, Florida)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jacques C. Bertrand (Gainesville, Florida)
ABSTRACT	A device and method of use for measuring the electrical charge of flying insects. The inventive device comprises measuring the charge induced by a flying insect and measuring the average of charge deposited on a metal screen due to the impact of multiple of insects on the screen.
FILED	Wednesday, September 11, 2013
APPL NO	14/023541
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/02 (20130101) A01M 1/06 (20130101) A01M 1/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/60 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 27/2611 (20130101) Original (OR) Class G01R 29/24 (20130101)
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09671493 — Automated scheduling of radar-cued camera system for optimizing visual inspection (detection) of radar targets

US 09671493	Khosla et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Deepak Khosla (Camarillo, California); David J. Huber (Calabasas, California); Yang Chen (Westlake Village, California)
ABSTRACT	Described is system for optimizing visual inspection of radar targets. The system detects radar hits with a radar system comprising radar and a radar-cued camera. The camera has a current state comprising a current slew position and a current zoom level. The radar hits are stored, and a set of metrics are determined for each radar hit. A track value (TV) metric is determined that combines the set of metrics for each zoom level of the camera. The camera sends a set of commands based on the TV metric, such that the camera slews from the current state to a new state. The new state is a position of a radar hit with the largest TV metric and a corresponding zoom level. Given the new state, an image is captured and processed to generate captured tracks. The current state of the camera is updated to reflect the new state.
FILED	Friday, September 19, 2014
APPL NO	14/491877
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/867 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/23296 (20130101)
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09671521 — Method and system for buried land mine detection through derivative analysis of laser interferometry

US 09671521	Louchard
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Eric M. Louchard (Miami, Florida)
ABSTRACT	A method of detecting land mines includes pre-processing a raw laser interferometer image, processing pre-processed image by calculating one or more derivatives having one or more peaks, along vectors extending in at least two different directions, mapping the peaks of said derivatives to create a derivative map, and detecting an anomalous signature in the derivative map.
FILED	Wednesday, July 15, 2015
APPL NO	14/800145
ART UNIT	2886 — Optics
CURRENT CPC	Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/28 (20130101) G01V 1/226 (20130101) G01V 8/12 (20130101) Original (OR) Class G01V 2210/48 (20130101) G01V 2210/121 (20130101)
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09671538 — Optical elements comprising cholesteric liquid crystal polymers

US 09671538	Pau et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The Arizona Board of Regents on Behalf of the Univeristy of Arizona (Tucson, Arizona)
ASSIGNEE(S)	The Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Stanley Pau (Tucson, Arizona); Wei-Liang Hsu (Norwalk, Connecticut)
ABSTRACT	A linear photopolymerizable polymer (LPP) layer is situated to align liquid crystal molecules in a cholesteric liquid crystal polymer (Ch-LCP) layer situated at or on the LPP layers. The Ch-LCP layer includes a patterned area and an unpatterned area. The patterned area and the un-patterned area have different optical properties. The Ch-LCP layer can be tuned to transmit light of a desired frequency and handedness. Single and multiple-layered LPP/Ch-LCP and/or LPP/LCP structures can be provided as patterned polarizers, patterned retarders and other devices.
FILED	Monday, November 18, 2013
APPL NO	14/440493
ART UNIT	2871 — Optics
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/36 (20130101) C09K 19/56 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3016 (20130101) Original (OR) Class
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09671563 — Through-substrate optical coupling to photonics chips

US 09671563	Doany et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Fuad Doany (Katonah, New York); Benjamin G. Lee (New York, New York); Clint L. Schow (Ossining, New York)
ABSTRACT	An optoelectronic integrated circuit for coupling light to or from an optical waveguide formed in an optical device layer in a near-normal angle to that layer. In an embodiment, the integrated circuit comprises a semiconductor body including a metal-dielectric stack, an optical device layer, a buried oxide layer and a semiconductor substrate arranged in series between first and second opposite sides of the semiconductor body. At least one optical waveguide is formed in the optical device layer for guiding light in a defined plane in that device layer. Diffractive coupling elements are disposed in the optical device layer to couple light from the waveguide toward the second surface of the semiconductor body at a near-normal angle to the defined plane in the optical device layer. In an embodiment, an optical fiber is positioned against the semiconductor body for receiving the light from the coupling elements.
FILED	Monday, March 14, 2016
APPL NO	15/069532
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/30 (20130101) Original (OR) Class G02B 6/32 (20130101) G02B 6/124 (20130101) G02B 6/136 (20130101) G02B 6/3652 (20130101) G02B 6/4214 (20130101) G02B 6/12002 (20130101) G02B 6/29323 (20130101) G02B 2006/12104 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/167 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101)
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09671670 — Inductance-tuned electro-optic modulators

US 09671670	Hollis et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Mark A. Hollis (Concord, Massachusetts); Reuel B. Swint (Billerica, Massachusetts); Dominic Siriani (Boston, Massachusetts); Joseph P. Donnelly (Carlisle, Massachusetts); Paul William Juodawlkis (Arlington, Massachusetts)
ASSIGNEE(S)	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S)	Mark A. Hollis (Concord, Massachusetts); Reuel B. Swint (Billerica, Massachusetts); Dominic Siriani (Boston, Massachusetts); Joseph P. Donnelly (Carlisle, Massachusetts); Paul William Juodawlkis (Arlington, Massachusetts)
ABSTRACT	An electro-optic modulator imparts the information contained in an electrical signal traveling along a transmission line onto an optical carrier by using signal-related variations in the electrical signal's voltage to modulate the refractive index or absorption in an electro-optic material through which the optical carrier propagates. For optimal bandwidth and modulation efficiency, the microwave and optical waves should be matched in velocity. However, conventional microwave transmission lines have a microwave velocity that is somewhat higher than the optical group velocity in typical optical waveguides. Tuning a microwave transmission line's capacitance reduces the microwave velocity, but also reduces the impedance below the 50Ω impedance of most microwave components. Conversely, tuning the microwave transmission line's inductance makes it possible to match the microwave velocity to the optical group velocity over bandwidths of 100 GHz or greater while maintaining a microwave impedance of 50Ω.
FILED	Tuesday, June 03, 2014
APPL NO	14/294422
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) G02B 2006/12097 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/01708 (20130101) G02F 1/01716 (20130101) G02F 1/2255 (20130101) Original (OR) Class G02F 1/2257 (20130101) G02F 2001/212 (20130101) G02F 2201/12 (20130101)
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09671672 — Method for generating a single photon for quantum information processing

US 09671672	Gammon et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Daniel Gammon (Waldorf, Maryland); Samuel Carter (Waldorf, Maryland); Allan S. Bracker (Alexandria, Virginia); Patrick Vora (Alexandria, Virginia)
ABSTRACT	A solid-state device for generating a single photon for quantum information processing, the device including: a quantum dot molecule including: a first singly-charged quantum dot; and a second singly-charged quantum dot; wherein the first singly-charged quantum dot is adjacent to the second singly-charged quantum dot; and a tunnel barrier that separates the first singly-charged quantum dot from the second singly-charged quantum dot.
FILED	Monday, March 20, 2017
APPL NO	15/463970
ART UNIT	2874 — Optics
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0126 (20130101) G02F 1/3556 (20130101) Original (OR) Class G02F 2001/01791 (20130101) G02F 2202/32 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Static Stores G11C 13/047 (20130101) G11C 13/048 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/774 (20130101)
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09671953 — Systems and methods using drawings which incorporate biometric data as security information

US 09671953	Wang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Cliff Xiaogang Wang (Cary, North Carolina); Wesley E. Snyder (Raleigh, North Carolina); Benjamin S. Riggan (Cary, North Carolina)
ABSTRACT	Systems and methods using drawings as security information are disclosed. According to an aspect, a computing device may include a touchscreen display configured to receive information for drawing a security picture. Further, the computing device may include a security manager configured to determine one or more characteristics associated with input of the gesture information. The security manager may also be configured to authenticate a user based on the drawn security picture and the one or more characteristics associated with input of the gesture information.
FILED	Thursday, February 27, 2014
APPL NO	14/192164
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 3/04883 (20130101) Original (OR) Class G06F 21/36 (20130101)
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09672008 — Pausible bisynchronous FIFO

US 09672008	Keller et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Energy (DOE)
APPLICANT(S)	NVIDIA Corporation (Santa Clara, California)
ASSIGNEE(S)	NVIDIA Corporation (Santa Clara, California)
INVENTOR(S)	Benjamin Andrew Keller (Oakland, California); Matthew Rudolph Fojtik (Raleigh, North Carolina); Brucek Kurdo Khailany (Austin, Texas)
ABSTRACT	A system, method, and computer program product are provided for a pausible bisynchronous FIFO. Data is written synchronously with a first clock signal of a first clock domain to an entry of a dual-port memory array and an increment signal is generated in the first clock domain. The increment signal is determined to transition near an edge of a second dock signal, where the second clock signal is a pausible clock signal. A next edge of the second clock signal of the second clock domain is delayed and the increment signal to the second clock domain and is transmitted.
FILED	Friday, November 20, 2015
APPL NO	14/948175
ART UNIT	2824 — Semiconductors/Memory
CURRENT CPC	Electric Digital Data Processing G06F 5/06 (20130101) Original (OR) Class G06F 2205/061 (20130101) Static Stores G11C 7/222 (20130101) G11C 8/16 (20130101) G11C 2207/2254 (20130101) G11C 2207/2272 (20130101)
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09672263 — Reliability engineering data integration

US 09672263	diPilla
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Michael A. diPilla (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Michael A. diPilla (Philadelphia, Pennsylvania)
ABSTRACT	Exemplary practice of the present invention provides an electronic system for integrating information from various network sources. The inventive system includes a server computer and at least one client computer (e.g., tablet). According to the software logic resident in the server computer, information is transmitted from various online resources (e.g., web-accessible collections of data) to an enterprise service bus (ESB), and the ESB collates some or all of the information received and stores the collated information in a network database. According to the software logic resident in each client computer, the collated information stored in the network database is downloaded onto an online webpage, parsed, stored in a local database, synched, and downloaded onto an offline webpage. A client can direct the server to collate a particular segment of information, thus affording the client offline access to pertinent, well-organized information on a portable, wireless platform such as a tablet.
FILED	Monday, June 23, 2014
APPL NO	14/312273
ART UNIT	2154 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/30575 (20130101) Original (OR) Class
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09672358 — Methods and apparatus for detecting malware samples with similar image sets

US 09672358	Long et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	INVINCEA, INC. (Fairfax, Virginia)
ASSIGNEE(S)	Invincea, Inc. (Fairfax, Virginia)
INVENTOR(S)	Alexander Mason Long (Sterling, Virginia); Joshua Daniel Saxe (Washington, District of Columbia)
ABSTRACT	An apparatus can include a processor that can extract, from an input binary file, an image data structure, and can scale the image data structure to a predetermined size, and/or modify the image data structure to represent a grayscale image. The processor can calculate a modified pixel value for each pixel in the image data structure, and can define a binary vector based on the modified pixel value for each pixel in the image data structure. The processor can also identify a set of nearest neighbor binary vectors for the binary vector based on a comparison between the binary vector and a set of reference binary vectors stored in a malware detection database. The processor can then determine a malware status of the input binary file based on the set of nearest neighbor binary vectors satisfying a similarity criterion associated with a known malware image from a known malware file.
FILED	Friday, November 04, 2016
APPL NO	15/343844
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/565 (20130101) Original (OR) Class
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09672394 — System and method for securing backscatter wireless communication

US 09672394	Han et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	University of Houston System (Houston, Texas); Trustees of Princeton University (Princeton, New Jersey); University of Miami (Miami, Florida)
ASSIGNEE(S)	UNIVERSITY OF MIAMI (Miami, Florida); UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Zhu Han (Sugar Land, Texas); Walid Saad (Coral Gables, Florida); Harold Vincent Poor (Princeton, New Jersey)
ABSTRACT	A system and method for securing backscatter communication. In one embodiment, a backscatter communication system includes a reader. The reader is configured to receive backscatter transmissions. The reader includes a transmitter configured to emit a radio frequency signal to induce backscatter communication. The transmitter includes a continuous wave (CW) carrier signal generator and a noise signal generator. The CW carrier signal generator produces a CW carrier signal. The noise signal generator generates a noise signal. The transmitter is configured to combine the CW carrier signal and the noise signal, and to transmit the combined signal to induce backscatter communication.
FILED	Tuesday, August 27, 2013
APPL NO	14/010650
ART UNIT	2686 — Cryptography and Security
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) Original (OR) Class Transmission H04B 5/0056 (20130101) H04B 5/0062 (20130101)
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09672593 — Lens distortion correction using a neurosynaptic system

US 09672593	Andreopoulos et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Alexander Andreopoulos (San Jose, California); Daniel F. Gruhl (San Jose, California); Michael Karasick (White Plains, New York); Dharmendra S. Modha (San Jose, California)
ABSTRACT	Embodiments of the invention provide a system and circuit for image distortion correction. The system includes neurosynaptic core circuits that: receive a set of inputs comprising image dimensions and pixel distortion coefficients for one or more image frames via one or more input core circuits, map each distorted pixel to zero or more undistorted pixels by processing the set of inputs corresponding to each pixel of the one or more image frames by the one or more input core circuits, and route corresponding pixel intensity values of each distorted pixel to output undistorted pixels for each image frame via one or more output core circuits.
FILED	Wednesday, June 25, 2014
APPL NO	14/315303
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/4604 (20130101) Image Data Processing or Generation, in General G06T 3/4046 (20130101) Original (OR) Class G06T 5/006 (20130101) G06T 2207/20084 (20130101)
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09672880 — Radiation upset detection

US 09672880	Buck et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Honeywell International Inc. (Morristown, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Timothy Merrill Buck (Oakdale, Minnesota); Paris D. Wiley (Tampa, Florida)
ABSTRACT	A radiation upset detector is provided. The radiation upset detector includes at least one radiation sensitive memory initialized with at least one respective known-signature word; and at least one radiation hardened logic circuitry communicatively coupled to the at radiation sensitive memory to check the known-signature word at at least a kHz rate to detects errors. Responsive to detecting an error in the known-signature word in the radiation sensitive memory, the radiation hardened logic circuitry sends an action command. At least one of: a memory size of the memory; a number of circuits in the logic circuitry; a clock rate for the checking the known-signature word; and at least one corruption threshold is selected based on system reliability requirements of the protected system including at least one of: an overall operational reliability requirement of the protected system; a probability of detection success; false alarm rates; and a required speed of detection.
FILED	Friday, October 10, 2014
APPL NO	14/511709
ART UNIT	2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Static Stores G11C 5/005 (20130101) G11C 7/02 (20130101) G11C 7/20 (20130101) Original (OR) Class G11C 11/4125 (20130101) G11C 29/52 (20130101)
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09672886 — Fast and low-power sense amplifier and writing circuit for high-speed MRAM

US 09672886	Wang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Kang L. Wang (Santa Monica, California); Pedram Khalili Amiri (Los Angeles, California); Hochul Lee (Los Angeles, California); Juan G. Alzate (Los Angeles, California)
ABSTRACT	A fast and low-power sense amplifier and writing circuit for high-speed Magnetic RAM (MRAM) which provides the long retention times and endurance of magnetic tunnel junction (MTJ) cells, while providing faster access speeds, verified writes, and an increased sensing margin. A high-speed and low-power pre-read and write sense amplifier (PWSA) provide VCMA effect precessional switching of MTJ cells which include pre-read and comparison steps which reduce power consumption. An embodiment of the PWSA circuit is described with write and pre-charge circuit, S and D latches, comparison circuit, and a differential amplifier and control circuit.
FILED	Tuesday, May 05, 2015
APPL NO	14/704936
ART UNIT	2827 — Semiconductors/Memory
CURRENT CPC	Static Stores G11C 11/16 (20130101) G11C 11/161 (20130101) G11C 11/1673 (20130101) Original (OR) Class G11C 11/1675 (20130101)
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09672943 — Apparatus for magnetic and electrostatic confinement of plasma

US 09672943	Rostoker et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Norman Rostoker (Oakland, California); Michl W. Binderbauer (Ladera Ranch, California)
ABSTRACT	A system and method for containing plasma and forming a Field Reversed Configuration (FRC) magnetic topology are described in which plasma ions are contained magnetically in stable, non-adiabatic orbits in the FRC. Further, the electrons are contained electrostatically in a deep energy well, created by tuning an externally applied magnetic field. The simultaneous electrostatic confinement of electrons and magnetic confinement of ions avoids anomalous transport and facilitates classical containment of both electrons and ions. In this configuration, ions and electrons may have adequate density and temperature so that upon collisions ions are fused together by nuclear force, thus releasing fusion energy. Moreover, the fusion fuel plasmas that can be used with the present confinement system and method are not limited to neutronic fuels only, but also advantageously include advanced fuels.
FILED	Thursday, June 02, 2016
APPL NO	15/172069
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Fusion Reactors G21B 1/05 (20130101) G21B 1/052 (20130101) Original (OR) Class Nuclear Power Plant G21D 7/00 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/03 (20130101) H05H 1/10 (20130101) H05H 1/12 (20130101) H05H 1/14 (20130101) H05H 1/16 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/122 (20130101) Y02E 30/126 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09673047 — Solid phase epitaxy of 3C—SiC on Si(001)

US 09673047	Li et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Connie H. Li (Alexandria, Virginia); Glenn G. Jernigan (Waldorf, Maryland); Berend T. Jonker (Waldorf, Maryland); Ramasis Goswami (Alexandria, Virginia); Carl S. Hellberg (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Connie H. Li (Alexandria, Virginia); Glenn G. Jernigan (Waldorf, Maryland); Berend T. Jonker (Waldorf, Maryland); Ramasis Goswami (Alexandria, Virginia); Carl S. Hellberg (Bethesda, Maryland)
ABSTRACT	A method of making a SiC buffer layer on a Si substrate comprising depositing an amorphous carbon layer on a Si(001) substrate, controlling the thickness of the amorphous carbon layer by controlling the time of the step of depositing the amorphous carbon layer, and forming a deposited film. A 3C—SiC buffer layer on Si(001) comprising a porous buffer layer of 3C—SiC on a Si substrate wherein the porous buffer layer is produced through a solid state reaction.
FILED	Thursday, October 01, 2015
APPL NO	14/872308
ART UNIT	2896 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02381 (20130101) H01L 21/02433 (20130101) H01L 21/02447 (20130101) H01L 21/02513 (20130101) H01L 21/02527 (20130101) H01L 21/02529 (20130101) H01L 21/02587 (20130101) Original (OR) Class H01L 21/02612 (20130101) H01L 21/02631 (20130101) H01L 21/02658 (20130101) H01L 29/045 (20130101)
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09673380 — Temperature and field stable relaxor-PT piezoelectric single crystals

US 09673380	Hackenberger et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Wesley S. Hackenberger (State College, Pennsylvania); Jun Luo (State College, Pennsylvania); Shujun Zhang (State College, Pennsylvania); Fei Li (State College, Pennsylvania); Thomas R. Shrout (Pennsylvania Furnance, Pennsylvania); Kevin A. Snook (State College, Pennsylvania); Raffi Sahul (State College, Pennsylvania)
ASSIGNEE(S)
INVENTOR(S)	Wesley S. Hackenberger (State College, Pennsylvania); Jun Luo (State College, Pennsylvania); Shujun Zhang (State College, Pennsylvania); Fei Li (State College, Pennsylvania); Thomas R. Shrout (Pennsylvania Furnance, Pennsylvania); Kevin A. Snook (State College, Pennsylvania); Raffi Sahul (State College, Pennsylvania)
ABSTRACT	The application is directed to piezoelectric single crystals having shear piezoelectric coefficients with enhanced temperature and/or electric field stability. These piezoelectric single crystal may be used, among other things, for vibration sensors as well as low frequency, compact sonar transducers with improved and/or enhanced performance.
FILED	Monday, November 24, 2014
APPL NO	14/551513
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 11/00 (20130101) C30B 29/30 (20130101) C30B 29/32 (20130101) C30B 33/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/18 (20130101) H01L 41/1875 (20130101) Original (OR) Class
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09673390 — Phase transformation in transition metal dichalcogenides

US 09673390	Reed et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of the Navy (DON)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Evan J. Reed (Stanford, California); Karel-Alexander Duerloo (Palo Alto, California); Yao Li (Palo Alto, California)
ABSTRACT	Devices including transition metal dichalcognides and methods of forming and operating such devices are disclosed. In one disclosed method, a layer of a transition metal dichalcogenide is provided, and a phase transformation of at least a region of the layer of the transition metal dichalcogenide is induced.
FILED	Friday, February 20, 2015
APPL NO	14/627296
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/03 (20130101) G02F 1/0054 (20130101) G02F 2203/11 (20130101) Static Stores G11C 13/0004 (20130101) G11C 13/047 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/24 (20130101) H01L 29/665 (20130101) H01L 45/06 (20130101) Original (OR) Class H01L 45/142 (20130101) H01L 45/143 (20130101) H01L 45/144 (20130101) H01L 45/1206 (20130101) H01L 45/1226 (20130101) H01L 45/1233 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09673504 — Miniaturized multi-section directional coupler using multi-layer MMIC process

US 09673504	Meharry
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	David E. Meharry (Lexington, Massachusetts)
ABSTRACT	A miniaturized multi-sectioned, directional coupler using a multi-layer MMIC process, the coupler comprising, a monolithic microwave integrated circuit, having a central section with a relatively tight coupling, surrounded by sections of lighter coupling, the relatively tight coupling being comprised of a pair of spiral coupled lines, and the lighter coupling being comprised of meandered edge couple lines with capacitive loading of the lines in several places.
FILED	Monday, August 17, 2015
APPL NO	14/827991
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/185 (20130101) H01P 5/187 (20130101) Original (OR) Class H01P 9/006 (20130101)
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09674076 — Set up of direct mapped routers located across independently managed compute and storage networks

US 09674076	Besaw et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Nathan A. Besaw (Defiance, Ohio); Bret G. Bidwell (Hopewell Junction, New York); John Dorfner (Rhinebeck, New York); Aruna V. Ramanan (Poughkeepsie, New York)
ABSTRACT	Embodiments relate to setting up direct mapped routers located across independently managed compute and storage networks for enabling multiple modes of communication over the cross-coupled links between the networks. An aspect includes identifying a characteristic of a local entity based on a unique location identifier assigned to the local entity and learning a characteristic of a remote entity based on a location identifier received over a cross-coupled link between the local entity and the remote entity. A port on a local entity router is then correlated with the received location identifier of the remote entity. A route is then built in the direct mapped router table at a location pointed to by the location identifier of the remote entity. An optimistic failover route is established from a storage entity to a compute entity when a cross-coupled link between the storage entity and the compute entity is broken.
FILED	Thursday, August 13, 2015
APPL NO	14/825392
ART UNIT	2452 — Computer Networks
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0654 (20130101) H04L 45/22 (20130101) Original (OR) Class H04L 45/28 (20130101)
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09674406 — Using dynamic mode decomposition for real-time background/foreground separation in video

US 09674406	Kutz et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Science Foundation (NSF)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	UNIVERSITY OF WASHINGTON (Seattle, Washington)
INVENTOR(S)	Jose Nathan Kutz (Seattle, Washington); Jacob Grosek (Seattle, Washington); Steven Brunton (Seattle, Washington); Xing Fu (Seattle, Washington); Seth Pendergrass (Seattle, Washington)
ABSTRACT	The technique of dynamic mode decomposition (DMD) is disclosed herein for the purpose of robustly separating video frames into background (low-rank) and foreground (sparse) components in real-time. Foreground/background separation is achieved at the computational cost of just one singular value decomposition (SVD) and one linear equation solve, thus producing results orders of magnitude faster than robust principal component analysis (RPCA). Additional techniques, including techniques for analyzing the video for multi-resolution time-scale components, and techniques for reusing computations to allow processing of streaming video in real time, are also described herein.
FILED	Monday, August 17, 2015
APPL NO	14/828396
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Pictorial Communication, e.g Television H04N 5/144 (20130101) H04N 5/2226 (20130101) Original (OR) Class
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09674616 — Dynamic acoustic impedance matching device and method

US 09674616	Ruffa
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Anthony A. Ruffa (Hope Valley, Rhode Island)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Anthony A. Ruffa (Hope Valley, Rhode Island)
ABSTRACT	A dynamic acoustic impedance matching device for an acoustic signal transmitted or received in a medium by a transducer includes a particle flow in an acoustic signal path of the transducer. The particle flow has an acoustic impedance between an acoustic impedance of the transducer and an acoustic impedance of the medium.
FILED	Friday, July 27, 2012
APPL NO	13/560398
ART UNIT	2651 — Videophones and Telephonic Communications
CURRENT CPC	Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 11/00 (20130101) Original (OR) Class H04R 23/004 (20130101)
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09674836 — Method and system for coexistence of radar and communication systems

US 09674836	Gormley et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	EDEN ROCK COMMUNICATIONS, LLC (Bothell, Washington)
ASSIGNEE(S)	SPECTRUM EFFECT, INC. (Seattle, Washington)
INVENTOR(S)	Eamonn Gormley (Bothell, Washington); Jungnam Yun (Bothell, Washington); Rekha Menon (Bothell, Washington)
ABSTRACT	A method for coexistence with a pulsed interference source in a communications network includes identifying transmission time intervals (TTIs) that are affected by pulses from the pulsed interference source and changing a transmission parameter for the TTIs that are affected by pulses.
FILED	Tuesday, July 29, 2014
APPL NO	14/446151
ART UNIT	2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 5/0078 (20130101) H04L 43/16 (20130101) Wireless Communication Networks H04W 16/14 (20130101) H04W 24/02 (20130101) H04W 72/0446 (20130101) Original (OR) Class
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Department of Energy (DOE)

09668884 — Method of making self-cleaning skin-like prosthetic polymer surfaces

US 09668884	Simpson et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	John T. Simpson (Clinton, Tennessee); Ilia N. Ivanov (Knoxville, Tennessee); Jason Shibata (Manhattan Beach, California)
ABSTRACT	An external covering and method of making an external covering for hiding the internal endoskeleton of a mechanical (e.g., prosthetic) device that exhibits skin-like qualities is provided. The external covering generally comprises an internal bulk layer in contact with the endoskeleton of the prosthetic device and an external skin layer disposed about the internal bulk layer. The external skin layer is comprised of a polymer composite with carbon nanotubes embedded therein. The outer surface of the skin layer has multiple cone-shaped projections that provide the external skin layer with superhydrophobicity. The carbon nanotubes are preferably vertically aligned between the inner surface and outer surface of the external skin layer in order to provide the skin layer with the ability to transmit heat. Superhydrophobic powders may optionally be used as part of the polymer composite or applied as a coating to the surface of the skin layer to enhance superhydrophobicity.
FILED	Monday, August 26, 2013
APPL NO	13/975434
ART UNIT	3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/76 (20130101) A61F 2/78 (20130101) A61F 2/586 (20130101) A61F 2/5044 (20130101) Original (OR) Class A61F 2002/5001 (20130101) A61F 2002/5055 (20130101) A61F 2002/5089 (20130101) A61F 2002/7665 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24612 (20150115)
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09668885 — Method of making self-cleaning skin-like prosthetic polymer surfaces

US 09668885	Simpson et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	John T. Simpson (Clinton, Tennessee); Ilia N. Ivanov (Knoxville, Tennessee); Jason Shibata (Manhattan Beach, California)
ABSTRACT	An external covering and method of making an external covering for hiding the internal endoskeleton of a mechanical (e.g., prosthetic) device that exhibits skin-like qualities is provided. The external covering generally comprises an internal bulk layer in contact with the endoskeleton of the prosthetic device and an external skin layer disposed about the internal bulk layer. The external skin layer is comprised of a polymer composite with carbon nanotubes embedded therein. The outer surface of the skin layer has multiple cone-shaped projections that provide the external skin layer with superhydrophobicity. The carbon nanotubes are preferably vertically aligned between the inner surface and outer surface of the external skin layer in order to provide the skin layer with the ability to transmit heat. Superhydrophobic powders may optionally be used as part of the polymer composite or applied as a coating to the surface of the skin layer to enhance superhydrophobicity.
FILED	Monday, August 26, 2013
APPL NO	13/975472
ART UNIT	3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/76 (20130101) A61F 2/78 (20130101) A61F 2/586 (20130101) A61F 2/5044 (20130101) Original (OR) Class A61F 2002/5001 (20130101) A61F 2002/5055 (20130101) A61F 2002/5089 (20130101) A61F 2002/7665 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24612 (20150115)
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09669098 — Metal-organic frameworks with exceptionally large pore aperatures

US 09669098	Yaghi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Energy (DOE)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Omar M. Yaghi (Berkeley, California); Hiroyasu Furukawa (Berkeley, California); Hexiang Deng (Albany, California)
ABSTRACT	The disclosure relates to metal organic frameworks or isoreticular metal organic frameworks, methods of production thereof, and methods of use thereof.
FILED	Monday, July 13, 2015
APPL NO	14/797312
ART UNIT	1671 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/24 (20130101) Original (OR) Class Separation B01D 53/02 (20130101) B01D 2253/204 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0225 (20130101) B01J 20/226 (20130101) B01J 20/28016 (20130101) B01J 20/28066 (20130101) B01J 20/28073 (20130101) B01J 20/28076 (20130101) B01J 2220/58 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/02 (20130101) C07F 3/06 (20130101) C07F 5/025 (20130101) C07F 7/2224 (20130101) Peptides C07K 14/435 (20130101)
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09669141 — Tissue-engineered pumps and valves and uses thereof

US 09669141	Parker et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California)
INVENTOR(S)	Kevin Kit Parker (Cambridge, Massachusetts); Josue A. Goss (Cambridge, Massachusetts); Sung-Jin Park (Lexington, Massachusetts); Andrew K. Capulli (Billerica, Massachusetts); Holly M. Golecki (Acton, Massachusetts); Janna C. Nawroth (Boston, Massachusetts); John O. Dabiri (Pasadena, California)
ABSTRACT	The present invention provides tissue-engineered pumps and valves, methods of fabricating such pumps and valves, and methods of use of such pumps and valves.
FILED	Friday, July 19, 2013
APPL NO	14/415945
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2415 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/12 (20130101) A61M 1/122 (20140204) A61M 1/127 (20130101) A61M 1/1003 (20140204) Original (OR) Class A61M 1/1037 (20130101) A61M 1/1053 (20130101) A61M 1/1098 (20140204) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5061 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49405 (20150115)
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09669329 — Extended residence time centrifugal contactor design modification and centrifugal contactor vane plate valving apparatus for extending mixing zone residence time

US 09669329	Wardle
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Kent E. Wardle (Brookfield, Illinois)
ABSTRACT	The present invention provides an annular centrifugal contactor, having a housing adapted to receive a plurality of flowing liquids; a rotor on the interior of the housing; an annular mixing zone, wherein the annular mixing zone has a plurality of fluid retention reservoirs with ingress apertures near the bottom of the annular mixing zone and egress apertures located above the ingress apertures of the annular mixing zone; and an adjustable vane plate stem, wherein the stem can be raised to restrict the flow of a liquid into the rotor or lowered to increase the flow of the liquid into the rotor.
FILED	Tuesday, September 30, 2014
APPL NO	14/501898
ART UNIT	1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 11/048 (20130101) Original (OR) Class B01D 15/1807 (20130101) B01D 2011/002 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 14/005 (20130101) B01J 19/18 (20130101) B01J 2219/00024 (20130101) B01J 2219/00094 (20130101) B01J 2219/185 (20130101)
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09669371 — Hydrogen generation systems utilizing sodium silicide and sodium silica gel materials

US 09669371	Wallace et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Intelligent Energy Limited (Loughborough, United Kingdom)
ASSIGNEE(S)	Intelligent Energy Limited (Loughborough, United Kingdom)
INVENTOR(S)	Andrew P. Wallace (Davis, California); John M. Melack (Winters, California); Michael Lefenfeld (New York, New York)
ABSTRACT	Systems, devices, and methods combine reactant materials and aqueous solutions to generate hydrogen. The reactant materials can sodium silicide or sodium silica gel. The hydrogen generation devices are used in fuels cells and other industrial applications. One system combines cooling, pumping, water storage, and other devices to sense and control reactions between reactant materials and aqueous solutions to generate hydrogen. Multiple inlets of varied placement geometries deliver aqueous solution to the reaction. The reactant materials and aqueous solution are churned to control the state of the reaction. The aqueous solution can be recycled and returned to the reaction. One system operates over a range of temperatures and pressures and includes a hydrogen separator, a heat removal mechanism, and state of reaction control devices. The systems, devices, and methods of generating hydrogen provide thermally stable solids, near-instant reaction with the aqueous solutions, and a non-toxic liquid by-product.
FILED	Monday, June 08, 2015
APPL NO	14/733596
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/02 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 3/06 (20130101) C01B 3/065 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0606 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/324 (20130101) Y02E 60/362 (20130101)
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09669379 — Solar thermochemical reactor, methods of manufacture and use thereof and thermogravimeter

US 09669379	Klausner et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC (Gainesville, Florida)
INVENTOR(S)	James F. Klausner (Gainesville, Florida); Joerg Petrasch (Gainesville, Florida)
ABSTRACT	A solar thermochemical reactor contains an outer member, an inner member disposed within an outer member, wherein the outer member surrounds the inner member and wherein the outer member has an aperture for receiving solar radiation. An inner cavity and an outer cavity are formed by the inner member and outer member and a reactive material that is capable of being magnetically stabilized is disposed in the outer cavity between the inner member and the outer member.
FILED	Friday, December 21, 2012
APPL NO	14/367495
ART UNIT	1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/42 (20130101) B01J 19/02 (20130101) B01J 19/087 (20130101) Original (OR) Class B01J 19/127 (20130101) B01J 2208/00451 (20130101) B01J 2219/085 (20130101) B01J 2219/0263 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/042 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/07 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Y02E 60/364 (20130101)
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09669464 — Methods of deoxygenating metals having oxygen dissolved therein in a solid solution

US 09669464	Zhang et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Ying Zhang (Salt Lake City, Utah); Zhigang Zak Fang (Salt Lake City, Utah); Pei Sun (Salt Lake City, Utah); Yang Xia (Salt Lake City, Utah); Chengshang Zhou (Salt Lake City, Utah)
ABSTRACT	A method of deoxygenating metal can include forming a mixture of: a metal having oxygen dissolved therein in a solid solution, at least one of metallic magnesium and magnesium hydride, and a magnesium-containing salt. The mixture can be heated at a deoxygenation temperature for a period of time under a hydrogen-containing atmosphere to form a deoxygenated metal. The deoxygenated metal can then be cooled. The deoxygenated metal can optionally be subjected to leaching to remove by-products, followed by washing and drying to produce a final deoxygenated metal.
FILED	Thursday, July 21, 2016
APPL NO	15/216549
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0048 (20130101) B22F 1/0085 (20130101) B22F 9/22 (20130101) Original (OR) Class Alloys C22C 14/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101)
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09669551 — Robotic hand and fingers

US 09669551	Salisbury et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Curt Michael Salisbury (Albuquerque, New Mexico); Kevin J. Dullea (Albuquerque, New Mexico)
ABSTRACT	Technologies pertaining to a robotic hand are described herein. The robotic hand includes one or more fingers releasably attached to a robotic hand frame. The fingers can abduct and adduct as well as flex and tense. The fingers are releasably attached to the frame by magnets that allow for the fingers to detach from the frame when excess force is applied to the fingers.
FILED	Thursday, September 10, 2015
APPL NO	14/850664
ART UNIT	3652 — Material and Article Handling
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 15/08 (20130101) B25J 15/0009 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/31 (20130101) Y10S 901/38 (20130101)
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09670064 — Production of heavy water

US 09670064	Spencer et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) National Security Complex and PANTEX Plant (Y-12) NNSA Critical Mission Site Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S)	Consolidated Nuclear Security, LLC (Reston, Virginia)
ASSIGNEE(S)	Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Larry S. Spencer (Knoxville, Tennessee); Sam W. Brown (Knoxville, Tennessee); Michael R. Phillips (Harriman, Tennessee)
ABSTRACT	Disclosed are methods and apparatuses for producing heavy water. In one embodiment, a catalyst is treated with high purity air or a mixture of gaseous nitrogen and oxygen with gaseous deuterium all together flowing over the catalyst to produce the heavy water. In an alternate embodiment, the deuterium is combusted to form the heavy water. In an alternate embodiment, gaseous deuterium and gaseous oxygen is flowed into a fuel cell to produce the heavy water. In various embodiments, the deuterium may be produced by a thermal decomposition and distillation process that involves heating solid lithium deuteride to form liquid lithium deuteride and then extracting the gaseous deuterium from the liquid lithium deuteride.
FILED	Thursday, September 27, 2012
APPL NO	13/628186
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 10/007 (20130101) Non-metallic Elements; Compounds Thereof; C01B 5/02 (20130101) Original (OR) Class Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101)
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09670237 — Phosphonium-based ionic liquids and their use in the capture of polluting gases

US 09670237	Dai et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	Sheng Dai (Knoxville, Tennessee); Congmin Wang (Hangzhou, China PRC); Huimin Luo (Knoxville, Tennessee); De-en Jiang (Knoxville, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Sheng Dai (Knoxville, Tennessee); Congmin Wang (Hangzhou, China PRC); Huimin Luo (Knoxville, Tennessee); De-en Jiang (Knoxville, Tennessee)
ABSTRACT	An ionic liquid composition having the following chemical structural formula: wherein R¹, R², R³, and R⁴are independently selected from hydrocarbon groups containing at least 1 and up to 20 carbon atoms, and X⁻is a cyclic anion that possesses a negatively-charged group reactive with a gaseous electrophilic species, particularly carbon dioxide or sulfur dioxide. Methods for capturing a gaseous electrophilic species, such as CO₂or SO₂, by contacting the gaseous electrophilic species with an ionic liquid according to Formula (1) are also described.
FILED	Thursday, September 22, 2011
APPL NO	13/240275
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 17/0064 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/5407 (20130101) Original (OR) Class Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101)
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09670253 — Antiviral vaccines with improved cellular immunogenicity

US 09670253	Barouch et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Dan H. Barouch (Boston, Massachusetts); Bette T. Korber (Los Alamos, New Mexico); William M. Fischer (Los Alamos, New Mexico)
ABSTRACT	The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects.
FILED	Thursday, February 26, 2015
APPL NO	14/632869
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 39/235 (20130101) A61K 39/275 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/24043 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) C12N 2740/16222 (20130101) C12N 2740/16234 (20130101) C12N 2740/16271 (20130101) C12N 2740/16322 (20130101) C12N 2740/16334 (20130101)
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09670258 — Positive modulator of bone morphogenic protein-2

US 09670258	Zamora et al.
FUNDED BY	Department of Energy (DOE) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	Ferring B.V. (Hoofddorp, Netherlands); Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S)	Ferring B.V. (Hoofddorp, Netherlands); Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S)	Paul O. Zamora (Gaithersburg, Maryland); Louis A. Pena (Poquott, New York); Xinhua Lin (Plainview, New York); Takahashi Kazuyuki (Germantown, Maryland)
ABSTRACT	Compounds of the present invention of formula I and formula II are disclosed in the specification and wherein the compounds are modulators of Bone Morphogenic Protein activity. Compounds are synthetic peptides having a non-growth factor heparin binding region, a linker, and sequences that bind specifically to a receptor for Bone Morphogenic Protein. Uses of compounds of the present invention in the treatment of bone lesions, degenerative joint disease and to enhance bone formation are disclosed.
FILED	Thursday, August 18, 2016
APPL NO	15/240977
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) A61K 38/00 (20130101) A61K 38/1875 (20130101) A61K 47/48246 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/51 (20130101) C07K 14/475 (20130101) C07K 14/503 (20130101) C07K 14/4705 (20130101) Original (OR) Class C07K 2319/00 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101)
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09670308 — Device and method for treatment of openings in vascular and septal walls

US 09670308	Singhal et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas)
INVENTOR(S)	Pooja Singhal (Dublin, California); Thomas S. Wilson (San Leandro, California); Elizabeth Cosgriff-Hernandez (College Station, Texas); Duncan J. Maitland (College Station, Texas)
ABSTRACT	A device, system and method for treatment of an opening in vascular and/or septal walls including patent foramen ovale. The device has wings/stops on either end, an axis core covered in a shape memory foam and is deliverable via a catheter to the affected opening, finally expanding into a vascular or septal opening where it is held in place by the expandable shape memory stops or wings.
FILED	Tuesday, March 12, 2013
APPL NO	13/797727
ART UNIT	3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 2017/00592 (20130101) A61B 2017/00606 (20130101) A61B 2017/00623 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/14 (20130101) C08G 18/73 (20130101) C08G 18/165 (20130101) C08G 18/6622 (20130101) Original (OR) Class C08G 63/00 (20130101) C08G 63/6852 (20130101) C08G 71/04 (20130101) C08G 2101/005 (20130101) C08G 2101/0083 (20130101) C08G 2230/00 (20130101) C08G 2280/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/00 (20130101) C08J 2375/06 (20130101)
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09670587 — Roll-to-roll light directed electrophoretic deposition system and method

US 09670587	Pascall et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Levermore National Security, LLC (Livermore, California)
INVENTOR(S)	Andrew J. Pascall (Livermore, California); Joshua Kuntz (Livermore, California)
ABSTRACT	A roll-to-roll light directed electrophoretic deposition system and method advances a roll of a flexible electrode web substrate along a roll-to-roll process path, where a material source is positioned to provide on the flexible electrode web substrate a thin film colloidal dispersion of electrically charged colloidal material dispersed in a fluid. A counter electrode is also positioned to come in contact with the thin film colloidal dispersion opposite the flexible electrode web substrate, where one of the counter electrode and the flexible electrode web substrate is a photoconductive electrode. A voltage source is connected to produce an electric potential between the counter electrode and the flexible electrode web substrate to induce electrophoretic deposition on the flexible electrode web substrate when the photoconductive electrode is rendered conductive, and a patterned light source is arranged to illuminate the photoconductive electrode with a light pattern and render conductive illuminated areas of the photoconductive electrode so that a patterned deposit of the electrically charged colloidal material is formed on the flexible electrode web substrate.
FILED	Wednesday, February 03, 2016
APPL NO	15/015062
ART UNIT	1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/22 (20130101) Original (OR) Class
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09670598 — Method of manufacturing tin-doped indium oxide nanofibers

US 09670598	Ozcan et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Soydan Ozcan (Oak Ridge, Tennessee); Amit K Naskar (Knoxville, Tennessee)
ABSTRACT	A method of making indium tin oxide nanofibers includes the step of mixing indium and tin precursor compounds with a binder polymer to form a nanofiber precursor composition. The nanofiber precursor composition is co-formed with a supporting polymer to form a composite nanofiber having a precursor composition nanofiber completely surrounded by the supporting polymer composition. The supporting polymer composition is removed from the composite nanofiber to expose the precursor composition nanofiber. The precursor composition nanofiber is then heated in the presence of oxygen such as O₂to form indium tin oxide and to remove the binder polymer to form an indium tin oxide nanofiber. A method of making metal oxide nanofibers is also disclosed.
FILED	Monday, March 30, 2015
APPL NO	14/673130
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 19/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/16 (20130101) C01P 2004/90 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/34 (20130101) D01D 5/36 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/08 (20130101) Original (OR) Class
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09671301 — Small-scale pressure sensors

US 09671301	Carroll et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	David L. Carroll (Winston-Salem, North Carolina); Faith M. Coldren (Strasbourg, France); Nicole H. Levi (Winston-Salem, North Carolina); Lawrence X. Webb (Winston-Salem, North Carolina); William D. Wagner (Clemmons, North Carolina); Thomas L. Smith (Winston-Salem, North Carolina); Brian Werner (Lancaster, Pennsylvania); J. Baxter Mcguirt (Winston-Salem, North Carolina); Manoj Namboothiry (West Lafayette, Indiana)
ASSIGNEE(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S)	David L. Carroll (Winston-Salem, North Carolina); Faith M. Coldren (Strasbourg, France); Nicole H. Levi (Winston-Salem, North Carolina); Lawrence X. Webb (Winston-Salem, North Carolina); William D. Wagner (Clemmons, North Carolina); Thomas L. Smith (Winston-Salem, North Carolina); Brian Werner (Lancaster, Pennsylvania); J. Baxter Mcguirt (Winston-Salem, North Carolina); Manoj Namboothiry (West Lafayette, Indiana)
ABSTRACT	The present invention provides a method of sensing pressure in a region of interest by providing a plurality of metallic particles operatively associated with one another in the region of interest (for example, wherein the metallic particles sustain a plasmon upon excitation), and with the metallic particles configured or positioned in relationship to one another so that a physical property of the particles (for example, the energy of the plasmon) varies in response to pressure; measuring the physical property of the metallic particles that varies in response to pressure; and then determining the pressure in the region of interest from the detected physical property (e.g., resistance, energy of the plasmon). Compositions, articles and formulations for carrying out the method in industrial and biomedical applications are also described.
FILED	Friday, September 28, 2007
APPL NO	12/443249
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/03 (20130101) A61B 5/445 (20130101) A61B 2562/0247 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 11/02 (20130101) Original (OR) Class
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09671327 — Ultrasensitive biochemical sensing device and method of sensing analytes

US 09671327	Pinchuk
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Anatoliy Pinchuk (Colorado Springs, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
INVENTOR(S)	Anatoliy Pinchuk (Colorado Springs, Colorado)
ABSTRACT	Systems and methods biochemically sense a concentration of a ligand using a sensor having a substrate having a metallic nanoparticle array formed onto a surface of the substrate. A light source is incident on the surface. A matrix is deposited over the nanoparticle array and contains a protein adapted to binding the ligand. A detector detects s-polarized and p-polarized light from the reflective surface. Spacing of nanoparticles in the array and wavelength of light are selected such that plasmon resonance occurs with an isotropic point such that −s and −p polarizations of the incident light result in substantially identical surface Plasmon resonance, wherein binding of the ligand to the protein shifts the resonance such that differences between the −S and −P polarizations give in a signal indicative of presence of the ligand.
FILED	Friday, March 16, 2012
APPL NO	13/422718
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) Original (OR) Class G01N 21/554 (20130101) G01N 33/54373 (20130101)
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09671536 — Electronic displays using optically pumped luminescent semiconductor nanocrystals

US 09671536	Weiss et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Shimon Weiss (Pinole, California); Michael C. Schlamp (Plainsboro, New Jersey); A. Paul Alivisatos (Oakland, California)
ABSTRACT	A multicolor electronic display is based on an array of luminescent semiconductor nanocrystals. Nanocrystals which emit tight of different colors are grouped into pixels. The nanocrystals are optically pumped to produce a multicolor display. Different sized nanocrystals are used to produce the different colors. A variety of pixel addressing systems can be used.
FILED	Monday, November 09, 2015
APPL NO	14/935765
ART UNIT	2879 — Optics
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Optical Elements, Systems, or Apparatus G02B 5/207 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/1333 (20130101) G02F 1/133362 (20130101) G02F 1/133509 (20130101) G02F 1/133528 (20130101) G02F 1/133617 (20130101) G02F 2202/36 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/3211 (20130101) H01L 51/5012 (20130101) H01L 2251/5369 (20130101)
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09672008 — Pausible bisynchronous FIFO

US 09672008	Keller et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Energy (DOE)
APPLICANT(S)	NVIDIA Corporation (Santa Clara, California)
ASSIGNEE(S)	NVIDIA Corporation (Santa Clara, California)
INVENTOR(S)	Benjamin Andrew Keller (Oakland, California); Matthew Rudolph Fojtik (Raleigh, North Carolina); Brucek Kurdo Khailany (Austin, Texas)
ABSTRACT	A system, method, and computer program product are provided for a pausible bisynchronous FIFO. Data is written synchronously with a first clock signal of a first clock domain to an entry of a dual-port memory array and an increment signal is generated in the first clock domain. The increment signal is determined to transition near an edge of a second dock signal, where the second clock signal is a pausible clock signal. A next edge of the second clock signal of the second clock domain is delayed and the increment signal to the second clock domain and is transmitted.
FILED	Friday, November 20, 2015
APPL NO	14/948175
ART UNIT	2824 — Semiconductors/Memory
CURRENT CPC	Electric Digital Data Processing G06F 5/06 (20130101) Original (OR) Class G06F 2205/061 (20130101) Static Stores G11C 7/222 (20130101) G11C 8/16 (20130101) G11C 2207/2254 (20130101) G11C 2207/2272 (20130101)
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09672293 — Systems and methods for automatically identifying and linking names in digital resources

US 09672293	Parker et al.
FUNDED BY	Department of Energy (DOE) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	Charles T. Parker (East Lansing, Michigan); Catherine M. Lyons (Edinburgh, United Kingdom); Gerald P. Roston (Saline, Michigan); George M. Garrity (Okemos, Michigan)
ASSIGNEE(S)	NAMESFORLIFE, LLC (East Lansing, Michigan)
INVENTOR(S)	Charles T. Parker (East Lansing, Michigan); Catherine M. Lyons (Edinburgh, United Kingdom); Gerald P. Roston (Saline, Michigan); George M. Garrity (Okemos, Michigan)
ABSTRACT	The present invention provides systems and methods for automatically identifying name-like-strings in digital resources, matching these name-like-string against a set of names held in an expertly curated database, and for those name-like-strings found in said database, enhancing the content by associating additional matter with the name, wherein said matter includes information about the names that is held within said database and pointers to other digital resources which include the same name and it synonyms.
FILED	Tuesday, January 12, 2010
APPL NO	12/685964
ART UNIT	2162 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/30864 (20130101) G06F 17/30887 (20130101) Original (OR) Class
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09673369 — Thermoelectric materials based on tetrahedrite structure for thermoelectric devices

US 09673369	Morelli et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Donald T. Morelli (White Lake, Michigan); Xu Lu (Lansing, Michigan); Vidvuds Ozolins (Los Angeles, California)
ABSTRACT	Thermoelectric materials based on tetrahedrite structures for thermoelectric devices and methods for producing thermoelectric materials and devices are disclosed.
FILED	Wednesday, July 03, 2013
APPL NO	14/413196
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/547 (20130101) C04B 35/645 (20130101) C04B 35/6262 (20130101) C04B 35/62645 (20130101) C04B 2235/77 (20130101) C04B 2235/80 (20130101) C04B 2235/81 (20130101) C04B 2235/662 (20130101) C04B 2235/3262 (20130101) C04B 2235/3272 (20130101) C04B 2235/3281 (20130101) C04B 2235/3284 (20130101) C04B 2235/3291 (20130101) C04B 2235/3294 (20130101) C04B 2235/6562 (20130101) C04B 2235/6565 (20130101) C04B 2235/6567 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) Original (OR) Class H01L 35/18 (20130101)
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09673447 — Method of operating a lithium-ion cell having a high-capacity cathode

US 09673447	Chen et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Guorong Chen (Dayton, Ohio); Yanbo Wang (Xenia, Ohio); Qing Fang (Dayton, Ohio); Xiqing Wang (Dayton, Ohio); Aruna Zhamu (Springboro, Ohio); Bor Z. Jang (Centerville, Ohio)
ASSIGNEE(S)	Nanotek Instruments, Inc. (Dayton, Ohio)
INVENTOR(S)	Guorong Chen (Dayton, Ohio); Yanbo Wang (Xenia, Ohio); Qing Fang (Dayton, Ohio); Xiqing Wang (Dayton, Ohio); Aruna Zhamu (Springboro, Ohio); Bor Z. Jang (Centerville, Ohio)
ABSTRACT	A method of operating a lithium-ion cell comprising (a) a cathode comprising a carbon or graphitic material having a surface area to capture and store lithium thereon; (b) an anode comprising an anode active material; (c) a porous separator disposed between the two electrodes; (d) an electrolyte in ionic contact with the two electrodes; and (e) a lithium source disposed in at least one of the two electrodes to obtain an open circuit voltage (OCV) from 0.5 volts to 2.8 volts when the cell is made; wherein the method comprises: (A) electrochemically forming the cell from the OCV to either a first lower voltage limit (LVL) or a first upper voltage limit (UVL), wherein the first LVL is no lower than 0.1 volts and the first UVL is no higher than 4.6 volts; and (B) cycling the cell between a second LVL and a second UVL.
FILED	Thursday, April 12, 2012
APPL NO	13/506324
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/0445 (20130101) H01M 4/483 (20130101) H01M 4/587 (20130101) H01M 4/1393 (20130101) Original (OR) Class H01M 10/44 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101)
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09673452 — Graphene oxide as a sulfur immobilizer in high performance lithium/sulfur cells

US 09673452	Zhang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Yuegang Zhang (Cupertino, California); Elton J. Cairns (Walnut Creek, California); Liwen Ji (Richland, Washington); Mumin Rao (El Cerrito, California)
ABSTRACT	The loss of sulfur cathode material as a result of polysulfide dissolution causes significant capacity fading in rechargeable lithium/sulfur cells. Embodiments of the invention use a chemical approach to immobilize sulfur and lithium polysulfides via the reactive functional groups on graphene oxide. This approach obtains a uniform and thin (˜tens of nanometers) sulfur coating on graphene oxide sheets by a chemical reaction-deposition strategy and a subsequent low temperature thermal treatment process. Strong interaction between graphene oxide and sulfur or polysulfides demonstrate lithium/sulfur cells with a high reversible capacity of 950-1400 mAh g⁻¹, and stable cycling for more than 50 deep cycles at 0.1 C.
FILED	Friday, September 28, 2012
APPL NO	14/347600
ART UNIT	1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 31/26 (20130101) Heterocyclic Compounds C07D 303/38 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) H01M 4/583 (20130101) Original (OR) Class H01M 4/625 (20130101) H01M 10/0566 (20130101)
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09673478 — Multi-layer coatings for bipolar rechargeable batteries with enhanced terminal voltage

US 09673478	Farmer et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Joseph C. Farmer (Tracy, California); James Kaschmitter (Pleasanton, California); Steve Pierce (Pleasanton, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Joseph C. Farmer (Tracy, California); James Kaschmitter (Pleasanton, California); Steve Pierce (Pleasanton, California)
ABSTRACT	A method for producing a multi-layer bipolar coated cell according to one embodiment includes applying a first active cathode material above a substrate to form a first cathode; applying a first solid-phase ionically-conductive electrolyte material above the first cathode to form a first electrode separation layer; applying a first active anode material above the first electrode separation layer to form a first anode; applying an electrically conductive barrier layer above the first anode; applying a second active cathode material above the anode material to form a second cathode; applying a second solid-phase ionically-conductive electrolyte material above the second cathode to form a second electrode separation layer; applying a second active anode material above the second electrode separation layer to form a second anode; and applying a metal material above the second anode to form a metal coating section. In another embodiment, the anode is formed prior to the cathode. Cells are also disclosed.
FILED	Wednesday, May 12, 2010
APPL NO	12/778978
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/622 (20130101) H01M 4/661 (20130101) H01M 10/044 (20130101) Original (OR) Class H01M 10/0418 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49115 (20150115)
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09673483 — Reactive sintering of ceramic lithium ion electrolyte membranes

US 09673483	Badding et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	CORNING INCORPORATED (Corning, New York)
ASSIGNEE(S)	Corning Incorporated (Corning, New York)
INVENTOR(S)	Michael Edward Badding (Campbell, New York); Indrajit Dutta (Horseheads, New York); Sriram Rangarajan Iyer (Cupertino, California); Brian Alan Kent (Horseheads, New York); Nadja Teresia Lonnroth (Corning, New York)
ABSTRACT	Disclosed herein are methods for making a solid lithium ion electrolyte membrane, the methods comprising combining a first reactant chosen from amorphous, glassy, or low melting temperature solid reactants with a second reactant chosen from refractory oxides to form a mixture; heating the mixture to a first temperature to form a homogenized composite, wherein the first temperature is between a glass transition temperature of the first reactant and a crystallization onset temperature of the mixture; milling the homogenized composite to form homogenized particles; casting the homogenized particles to form a green body; and sintering the green body at a second temperature to form a solid membrane. Solid lithium ion electrolyte membranes manufactured according to these methods are also disclosed herein.
FILED	Monday, January 19, 2015
APPL NO	14/599692
ART UNIT	1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 25/45 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 19/06 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) H01M 2300/0071 (20130101)
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09673667 — System and method for preventing stator permanent magnet demagnetization during vacuum pressure impregnation

US 09673667	Raminosoa et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Tsarafidy Raminosoa (Niskayuna, New York); James Pellegrino Alexander (Ballston Lake, New York); Ayman Mohamed Fawzi EL-Refaie (Niskayuna, New York)
ABSTRACT	A permanent magnet electrical machine includes a stator having conductive windings wound thereon and one or more permanent magnets embedded in the stator. A magnetic keeper element is positioned on the stator so as to form a magnetic flux path with the permanent magnets, with the magnetic keeper element closing the magnetic flux path of the permanent magnets by providing a low reluctance flux path to magnetic flux generated by the permanent magnets. A vacuum pressure impregnation (VPI) process is performed on the stator to increase a thermal conductivity of the windings, with the VPI process including a curing step that is performed at a selected temperature. The magnetic keeper element sets an operating point of the permanent magnets to an internal flux density level above a demagnetization threshold associated with the selected temperature at which the curing step is performed.
FILED	Tuesday, July 22, 2014
APPL NO	14/337469
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Dynamo-electric Machines H02K 1/17 (20130101) Original (OR) Class H02K 3/30 (20130101) H02K 15/03 (20130101) H02K 15/12 (20130101) H02K 21/38 (20130101) H02K 21/44 (20130101)
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09674026 — Beam position monitor for energy recovered linac beams

US 09674026	Powers et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Thomas Jefferson National Accelerator Facility (TJNAF) Federally Funded Research and Development Center (FFRDC) Operated by Jefferson Science Associates, LLC (JSA) at Newport News, VA
APPLICANT(S)	JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia)
ASSIGNEE(S)	JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia)
INVENTOR(S)	Thomas Powers (Poquoson, Virginia); Pavel Evtushenko (Yorktown, Virginia)
ABSTRACT	A method of determining the beam position in an energy recovered linac (ERL). The method makes use of in phase and quadrature (I/Q) demodulation techniques to separate the pickup signal generated by the electromagnetic fields generated by the first and second pass beam in the energy recovered linac. The method includes using analog or digital based I/Q demodulation techniques in order to measure the relative amplitude of the signals from a position sensitive beam pickup such as a button, strip line or microstripline beam position monitor.
FILED	Thursday, May 26, 2016
APPL NO	15/165498
ART UNIT	2634 — Digital Communications
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1049 (20130101) A61N 5/1069 (20130101) A61N 5/1077 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/3827 (20130101) Original (OR) Class
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09674406 — Using dynamic mode decomposition for real-time background/foreground separation in video

US 09674406	Kutz et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Science Foundation (NSF)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	UNIVERSITY OF WASHINGTON (Seattle, Washington)
INVENTOR(S)	Jose Nathan Kutz (Seattle, Washington); Jacob Grosek (Seattle, Washington); Steven Brunton (Seattle, Washington); Xing Fu (Seattle, Washington); Seth Pendergrass (Seattle, Washington)
ABSTRACT	The technique of dynamic mode decomposition (DMD) is disclosed herein for the purpose of robustly separating video frames into background (low-rank) and foreground (sparse) components in real-time. Foreground/background separation is achieved at the computational cost of just one singular value decomposition (SVD) and one linear equation solve, thus producing results orders of magnitude faster than robust principal component analysis (RPCA). Additional techniques, including techniques for analyzing the video for multi-resolution time-scale components, and techniques for reusing computations to allow processing of streaming video in real time, are also described herein.
FILED	Monday, August 17, 2015
APPL NO	14/828396
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Pictorial Communication, e.g Television H04N 5/144 (20130101) H04N 5/2226 (20130101) Original (OR) Class
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National Science Foundation (NSF)

09668804 — Automated cell patch clamping method and apparatus

US 09668804	Kodandaramaiah et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) NIH Office of the Director (NIHOD) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Engineering (ENG) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	Suhasa Bangalore Kodandaramaiah (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Crag Richard Forest (Atlanta, Georgia); Brian Yichiun Chow (Cambridge, Massachusetts); Giovanni Talei Franzesi (Boston, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Suhasa Bangalore Kodandaramaiah (Somerville, Massachusetts); Edward Stuart Boyden (Chestnut Hill, Massachusetts); Crag Richard Forest (Atlanta, Georgia); Brian Yichiun Chow (Cambridge, Massachusetts); Giovanni Talei Franzesi (Boston, Massachusetts)
ABSTRACT	In an automated methodology for carrying out in vivo cell patch clamping, a cell patch clamping device is automatically moved into position and targeted to a neuron. Neuron contact is determined by analyzing the temporal series of measured resistance levels at the cell patch clamping device as it is moved. The difference between successive resistance levels is computed and compared to a threshold, which must be exceeded for a minimum number of computations before neuron contact is assumed. Pneumatic control methods are used to achieve gigaseal formation and cell break-in, leading to whole-cell patch clamp formation. An automated robotic system capable of performing this methodology automatically performs patch clamping in vivo, automatically detecting cells by analyzing the temporal sequence of electrode impedance changes. By continuously monitoring the patching process and rapidly executing actions triggered by specific measurements, the robot can rapidly find neurons in the living brain and establish recordings.
FILED	Tuesday, November 13, 2012
APPL NO	13/676082
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0538 (20130101) A61B 5/04001 (20130101) A61B 5/6885 (20130101) A61B 18/14 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 2503/40 (20130101)
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09669141 — Tissue-engineered pumps and valves and uses thereof

US 09669141	Parker et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California)
INVENTOR(S)	Kevin Kit Parker (Cambridge, Massachusetts); Josue A. Goss (Cambridge, Massachusetts); Sung-Jin Park (Lexington, Massachusetts); Andrew K. Capulli (Billerica, Massachusetts); Holly M. Golecki (Acton, Massachusetts); Janna C. Nawroth (Boston, Massachusetts); John O. Dabiri (Pasadena, California)
ABSTRACT	The present invention provides tissue-engineered pumps and valves, methods of fabricating such pumps and valves, and methods of use of such pumps and valves.
FILED	Friday, July 19, 2013
APPL NO	14/415945
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2415 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/12 (20130101) A61M 1/122 (20140204) A61M 1/127 (20130101) A61M 1/1003 (20140204) Original (OR) Class A61M 1/1037 (20130101) A61M 1/1053 (20130101) A61M 1/1098 (20140204) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5061 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49405 (20150115)
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09669232 — Method for non-invasive brain stimulation

US 09669232	Khizroev et al.
FUNDED BY	Department of Defense (DOD) Defense MicroElectronics Activity (DMEA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF)
APPLICANT(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S)	Sakhrat Khizroev (Coral Gables, Florida); Madhavan P. N. Nair (Coral Gables, Florida)
ABSTRACT	Magneto-electric nanoparticles in a subject interact with an external magnetic field to cause stimulation of neural networks in the subject. Electric signals in the neural network are coupled to magnetic dipoles induced in the nanoparticles to cause changes in electric pulse sequences of the subject's brain.
FILED	Thursday, February 04, 2016
APPL NO	15/015760
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/40 (20130101) A61N 2/02 (20130101) A61N 2/006 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0045 (20130101)
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09669388 — Catalysis by metal nanoparticles dispersed within a hierarchically porous carbon material

US 09669388	Bakker et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Board of Trustees of The University of Alabama (Tuscaloosa, Alabama)
ASSIGNEE(S)	The Board Trustees of The University of Alabama (Tuscaloosa, Alabama)
INVENTOR(S)	Martin G. Bakker (Tuscaloosa, Alabama); Franchessa Maddox Sayler (Tuscaloosa, Alabama); Kevin Shaughnessy (Tuscaloosa, Alabama)
ABSTRACT	Disclosed are hierarchically porous carbon materials with a plurality of discreet nanoparticles dispersed on their carbon phase. The materials possess a continuous network of pores that spans the porous material, permitting the flow of fluids into and through the material. The porous materials can be used as heterogeneous catalysts.
FILED	Tuesday, December 08, 2015
APPL NO	14/962342
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) Original (OR) Class B01J 21/185 (20130101) B01J 23/42 (20130101) B01J 23/44 (20130101) B01J 23/72 (20130101) B01J 23/462 (20130101) B01J 23/464 (20130101) B01J 23/755 (20130101) B01J 35/002 (20130101) B01J 35/006 (20130101) B01J 35/08 (20130101) B01J 35/0013 (20130101) B01J 35/0053 (20130101) B01J 35/109 (20130101) B01J 35/1061 (20130101) B01J 35/1066 (20130101) B01J 35/1071 (20130101) B01J 35/1076 (20130101) B01J 35/1095 (20130101) B01J 37/06 (20130101) B01J 37/08 (20130101) B01J 37/16 (20130101) B01J 37/0018 (20130101) B01J 37/18 (20130101) B01J 37/084 (20130101) B01J 37/088 (20130101) B01J 37/0201 (20130101) B01J 37/0207 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/52 (20130101) C04B 35/52 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/0032 (20130101) C04B 38/045 (20130101) C04B 38/0054 (20130101) C04B 38/0054 (20130101) C04B 38/0058 (20130101) C04B 38/0058 (20130101) C04B 38/0064 (20130101) C04B 38/0064 (20130101) C04B 38/0615 (20130101) Acyclic or Carbocyclic Compounds C07C 2/861 (20130101) C07C 2/861 (20130101) C07C 15/52 (20130101) C07C 41/30 (20130101) C07C 67/343 (20130101) C07C 67/343 (20130101) C07C 69/618 (20130101) C07C 209/36 (20130101) C07C 209/36 (20130101) C07C 211/46 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 255/50 (20130101) C07C 255/57 (20130101) C07C 2521/18 (20130101) C07C 2523/44 (20130101)
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09670074 — Nanoporous silica polyamine composites with surface-bound zirconium (IV) and methods of use

US 09670074	Rosenberg et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The University of Montana (Missoula, Montana)
ASSIGNEE(S)	The University of Montana (Missoula, Montana)
INVENTOR(S)	Edward Rosenberg (Missoula, Montana); Varadharajan Kailasam (Towanda, Pennsylvania); Daniel Nielsen (Burlington, Vermont)
ABSTRACT	Silica polyamine composites (SPC) made from silanized amorphous nano-porous silica gel and poly(allylamine) (BP-1) were functionalized with phosphorus acid using the Mannich reaction, resulting in a phosphonic acid modified composite (BPAP). Zirconium (IV) was immobilized on BPAP. Arsenate anions strongly adsorbed on the ZrBPAP composite in the pH range 2 to 8, while arsenite only adsorbed well at pH 10. Regeneration of the resin was carried out successfully for As(V) and As(III) using 2M-H₂SO₄. Four adsorption/desorption cycles were performed for As(V) at pH 4 without significant decrease in the uptake performance. ZrBPAP capture capacity and kinetics for arsenate were tested for longevity over 1000 cycles with only a marginal loss of performance.
FILED	Wednesday, November 06, 2013
APPL NO	14/073742
ART UNIT	1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/345 (20130101) B01J 20/3204 (20130101) B01J 20/3236 (20130101) B01J 20/3272 (20130101) B01J 20/3433 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) Original (OR) Class C02F 1/285 (20130101) C02F 2101/103 (20130101)
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09670264 — Water soluble G-protein coupled receptor

US 09670264	Liu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Renyu Liu (Media, Pennsylvania); Jeffery G Saven (Philadelphia, Pennsylvania); Jose Manuel Perez-Aguilar (New York, New York); Felipe Matsunaga (Olmsted Township, Ohio); Jin Xi (Media, Pennsylvania)
ABSTRACT	Described herein are recombinant integral membrane proteins having multiple transmembrane domains that have been engineered to be less hydrophobic, through alteration of the amino acid sequence of the native protein, but retain the ability to bind their natural ligand. The decreased hydrophobicity of the described proteins makes them more water soluble than the native protein, which allows the described proteins to be expressed in bacteria in large quantities and isolated in the absence of membranes, all while retaining the ability to interact with known ligands.
FILED	Friday, April 25, 2014
APPL NO	14/786578
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 2319/21 (20130101) C07K 2319/42 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/566 (20130101) G01N 2500/04 (20130101)
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09670589 — Alkali uranium fluorophosphate-based crystals and methods of fabrication

US 09670589	Mann et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	James M Mann (Springboro, Ohio); Eric Hunt (Glen Rock, Pennsylvania)
ABSTRACT	A method of synthesizing alkali uranium fluorophosphate crystals. The method includes combining a uranium-based feedstock with a mineralizer solution. The mineralizer solution includes an alkali nutrient, a phosphate, and a fluoride. The feedstock and mineralizer solution are pressurized and a thermal gradient applied thereto such that a first portion of the feedstock and the mineralizer solution is heated to a temperature that is greater than a temperature of a second portion of the feedstock and the mineralizer solution. Uranium nutrient enters the mineralizer solution from the feedstock in the first portion and uranium nutrient precipitates to spontaneously form crystals in the second portion.
FILED	Tuesday, March 22, 2016
APPL NO	15/077347
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 25/45 (20130101) C01B 25/455 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/006 (20130101) C01G 43/06 (20130101) C01G 43/025 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/76 (20130101) C01P 2002/77 (20130101) C01P 2006/60 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7709 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/10 (20130101) Original (OR) Class C30B 7/14 (20130101) C30B 29/12 (20130101) C30B 29/14 (20130101) C30B 29/16 (20130101)
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09671409 — Ultrathin calcinated films on a gold surface for highly effective laser desorption/ionization of biomolecules

US 09671409	Cheng et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Quan Cheng (Irvine, California); Jicheng Duan (Irvine, California); Matthew James Linman (Riverside, California)
ABSTRACT	A nanoscale calcinated silicate film fabricated on a gold substrate for highly effective, matrix-free laser desorption ionization mass spectrometry (LDI-MS) analysis of biomolecules. The calcinated film is prepared by a layer-by-layer (LbL) deposition/calcination process wherein the thickness of the silicate layer and its surface properties are precisely controlled. The film exhibits outstanding efficiency in LDI-MS with extremely low background noise in the low-mass region, allowing for effective analysis of low mass weight samples and detection of large biomolecules including amino acids, peptides and proteins. Additional advantages for the calcinated film include ease of preparation and modification, high reproducibility, low cost and excellent reusability. Experimental parameters that influence LDI on calcinated films have been systemically investigated. Presence of citric acid in the sample significantly enhances LDI performance by facilitating protonation of the analyte and reducing fragmentation. The wetting property and surface roughness appear to be important factors that manipulate LDI performance of the analytes. This new substrate presents a marked advance in the development of matrix-free mass spectrometric methods and is uniquely suited for analysis of biomolecules over a broad mass range with high sensitivity.
FILED	Friday, November 06, 2015
APPL NO	14/934755
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/14 (20130101) C23C 18/165 (20130101) C23C 18/1212 (20130101) C23C 18/1241 (20130101) C23C 18/1283 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6851 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115)
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09673399 — Floating evaporative assembly of aligned carbon nanotubes

US 09673399	Arnold et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Michael Scott Arnold (Middleton, Wisconsin); Harold T. Evensen (Verona, Wisconsin); Gerald Joseph Brady (Madison, Wisconsin); Padma Gopalan (Madison, Wisconsin); Yongho Joo (Madison, Wisconsin)
ABSTRACT	High density films of semiconducting single-walled carbon nanotubes having a high degree of nanotube alignment are provided. Also provided are methods of making the films and field effect transistors (FETs) that incorporate the films as conducting channel materials. The single-walled carbon nanotubes are deposited from a thin layer of organic solvent containing solubilized single-walled carbon nanotubes that is continuously supplied to the surface of an aqueous medium, inducing evaporative self-assembly upon contacting a solid substrate.
FILED	Wednesday, June 29, 2016
APPL NO	15/196325
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/18 (20130101) B05D 1/202 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0226 (20130101) C01B 31/0273 (20130101) C01B 2202/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/037 (20130101) C09D 11/52 (20130101) C09D 11/106 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0669 (20130101) H01L 51/0007 (20130101) H01L 51/0039 (20130101) Original (OR) Class H01L 51/0043 (20130101) H01L 51/0048 (20130101) H01L 51/0558 (20130101) H01L 51/0566 (20130101)
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09673527 — Folded patch antenna platform

US 09673527	Yoon et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Yong-Kyu Yoon (Gainesville, Florida); Gloria Jung-a Kim (Gainesville, Florida); Xiaoyu Cheng (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	Yong-Kyu Yoon (Gainesville, Florida); Gloria Jung-a Kim (Gainesville, Florida); Xiaoyu Cheng (Gainesville, Florida)
ABSTRACT	Various systems and methods are provided for folded patch antennas. In one embodiment, among others, a folded patch antenna includes a patch disposed on an outer side of a flexible substrate and a ground plane disposed on an inner side of the flexible substrate opposite the patch. The flexible substrate is folded to form an enclosed cavity defined by the inner side of the flexible substrate. The ground plane may provide electromagnetic interference (EMI) shielding of the cavity. In another embodiment, among others, a folded patch antenna platform includes a flexible substrate, a folded patch antenna, and a transceiver mounted on the flexible substrate. The folded patch antenna includes a patch communicatively coupled to the transceiver and a ground plane, which are disposed on opposite sides of the flexible substrate.
FILED	Friday, July 06, 2012
APPL NO	14/126950
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/24 (20130101) H01Q 1/38 (20130101) H01Q 1/273 (20130101) H01Q 5/364 (20150115) H01Q 9/0414 (20130101) H01Q 9/0442 (20130101) Original (OR) Class
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09673729 — Power processing methods and apparatus for photovoltaic systems

US 09673729	Perreault et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	David Perreault (Brookline, Massachusetts); Robert Pilawa-Podgurski (Cambridge, Massachusetts); Charles Sullivan (West Lebanon, New Hampshire); Alexander Latham (Norwich, Vermont)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Darmouth College (Hanover, New Hampshire)
INVENTOR(S)	David Perreault (Brookline, Massachusetts); Robert Pilawa-Podgurski (Cambridge, Massachusetts); Charles Sullivan (West Lebanon, New Hampshire); Alexander Latham (Norwich, Vermont)
ABSTRACT	High power output may be obtained from a photovoltaic (PV) system by controlling each photovoltaic cell of a solar array individually to operate at its maximum power point. Each cell may have associated power electronics and control circuitry that may be integrated together on a chip which may be advantageously implemented in CMOS, enabling reductions in cost and size. A perturb and observe algorithm may be used to find the maximum power point by measuring the power produced at different operating points, and modifying the operating point in the direction of increased power production. In one aspect, performance of a perturb and observe algorithm may be improved in the presence of noise.
FILED	Thursday, June 23, 2011
APPL NO	13/805452
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Systems for Regulating Electric or Magnetic Variables G05F 1/67 (20130101) G05F 1/571 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02021 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/383 (20130101) H02J 3/385 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/44 (20130101) Original (OR) Class H02M 2001/0077 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/563 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/685 (20150401) Y10T 307/707 (20150401)
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09673960 — Full duplex reconfigurable antenna self-interference cancellation systems

US 09673960	Eltawil et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Regents Of The University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Ahmed Mohamed Eltawil (Oakland, California); Elsayed A. Ahmed (Oakland, California); Bedri A. Cetiner (North Logan, Utah)
ABSTRACT	Embodiments of full-duplex systems with reconfigurable antennas are described. In one embodiment, a full-duplex reconfigurable antenna transceiver includes a transmit chain, a receive chain, and a reconfigurable antenna having a plurality of reconfigurable modes. The transceiver may also include an antenna controller configured to set a mode of the reconfigurable antenna. According to other aspects, the transceiver may also include a signal processor configured to transmit a set of training symbols during a training interval. The antenna controller may be further configured to select a respective mode of the reconfigurable antenna for each training symbol in the set of training symbols. Additionally, the antenna controller may be configured to calculate a received Signal-of-Interest to Interferer Ratio (SIR) for each training symbol of the set of training symbols. In this context, a full-duplex system utilizing a reconfigurable antenna may achieve significant rate improvement compared to half-duplex systems.
FILED	Friday, December 19, 2014
APPL NO	14/576295
ART UNIT	2464 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 1/525 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/14 (20130101) H04L 5/1453 (20130101) H04L 5/1461 (20130101) Original (OR) Class Wireless Communication Networks H04W 24/10 (20130101) H04W 88/06 (20130101)
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09674210 — Determining risk of malware infection in enterprise hosts

US 09674210	Oprea et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	EMC Corporation (Hopkinton, Massachusetts); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	EMC IP Holding Company LLC (Hopkinton, Massachusetts); University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Alina M. Oprea (Arlington, Massachusetts); Ting-Fang Yen (Waltham, Massachusetts); Viktor Heorhiadi (Chapel Hill, North Carolina); Michael Kendrick Reiter (Chapel Hill, North Carolina); Ari Juels (Brookline, Massachusetts)
ABSTRACT	A processing device comprises a processor coupled to a memory and is configured to obtain data characterizing host devices of a computer network of an enterprise. The data is applied to a logistic regression model to generate malware infection risk scores for respective ones of the host devices. The malware infection risk scores indicate likelihoods that the respective host devices will become infected with malware. The logistic regression model incorporates features of the host devices including at least user demographic features, virtual private network (VPN) activity features and web activity features of the host devices, and the data characterizing the host devices comprises data for the incorporated features. Proactive measures are taken to prevent malware infection in a subset of the host devices based at least in part on the malware infection risk scores. The processing device may be implemented in the computer network or an associated network security system.
FILED	Wednesday, November 26, 2014
APPL NO	14/554492
ART UNIT	2435 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0272 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 67/22 (20130101)
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09674406 — Using dynamic mode decomposition for real-time background/foreground separation in video

US 09674406	Kutz et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Science Foundation (NSF)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	UNIVERSITY OF WASHINGTON (Seattle, Washington)
INVENTOR(S)	Jose Nathan Kutz (Seattle, Washington); Jacob Grosek (Seattle, Washington); Steven Brunton (Seattle, Washington); Xing Fu (Seattle, Washington); Seth Pendergrass (Seattle, Washington)
ABSTRACT	The technique of dynamic mode decomposition (DMD) is disclosed herein for the purpose of robustly separating video frames into background (low-rank) and foreground (sparse) components in real-time. Foreground/background separation is achieved at the computational cost of just one singular value decomposition (SVD) and one linear equation solve, thus producing results orders of magnitude faster than robust principal component analysis (RPCA). Additional techniques, including techniques for analyzing the video for multi-resolution time-scale components, and techniques for reusing computations to allow processing of streaming video in real time, are also described herein.
FILED	Monday, August 17, 2015
APPL NO	14/828396
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Pictorial Communication, e.g Television H04N 5/144 (20130101) H04N 5/2226 (20130101) Original (OR) Class
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National Aeronautics and Space Administration (NASA)

09669921 — Active aircraft pylon noise control system

US 09669921	Thomas et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (Washington, District of Columbia)
INVENTOR(S)	Russell H. Thomas (Yorktown, Virginia); Michael J. Czech (Issaquah, Washington); Alaa A. Elmiligui (Virginia Beach, Virginia)
ABSTRACT	An active pylon noise control system for an aircraft includes a pylon structure connecting an engine system with an airframe surface of the aircraft and having at least one aperture to supply a gas or fluid therethrough, an intake portion attached to the pylon structure to intake a gas or fluid, a regulator connected with the intake portion via a plurality of pipes, to regulate a pressure of the gas or fluid, a plenum chamber formed within the pylon structure and connected with the regulator, and configured to receive the gas or fluid as regulated by the regulator, and a plurality of injectors in communication with the plenum chamber to actively inject the gas or fluid through the plurality of apertures of the pylon structure.
FILED	Monday, May 04, 2015
APPL NO	14/703288
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeroplanes; Helicopters B64C 7/02 (20130101) Original (OR) Class B64C 21/04 (20130101) B64C 2220/00 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/26 (20130101)
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09671332 — Miniature tunable laser spectrometer for detection of a trace gas

US 09671332	Christensen
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Lance E. Christensen (Baldwin Park, California)
ABSTRACT	An open-path laser spectrometer (OPLS) for measuring a concentration of a trace gas, the OPLS including an open-path multi-pass analysis region including a first mirror, a second mirror at a distance and orientation from the first mirror, and a support structure for locating the mirrors, a laser coupled to the analysis region and configured to emit light of a wavelength range and to enable a plurality of reflections of the emitted light between the mirrors, a detector coupled to the analysis region and configured to detect a portion of the emitted light impinging on the detector and to generate a corresponding signal, and an electronic system coupled to the laser and the detector, and configured to adjust the wavelength range of the emitted light from the laser based on the generated signal, and to measure the concentration of the trace gas based on the generated signal.
FILED	Thursday, January 23, 2014
APPL NO	14/162578
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/031 (20130101) G01N 21/39 (20130101) Original (OR) Class G01N 21/3504 (20130101) G01N 2021/399 (20130101) G01N 2021/3513 (20130101) G01N 2201/0221 (20130101)
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09671507 — Solid-state neutron detector device

US 09671507	Bensaoula et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	University of Houston System (Houston, Texas)
ASSIGNEE(S)	UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S)	Abdelhak Bensaoula (Houston, Texas); David Starikov (Houston, Texas); Rajeev Pillai (Manvel, Texas)
ABSTRACT	The structure and methods of fabricating a high efficiency compact solid state neutron detector based on III-Nitride semiconductor structures deposited on a substrate. The operation of the device is based on absorption of neutrons, which results in generation of free carriers.
FILED	Tuesday, March 24, 2015
APPL NO	14/667409
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Measurement of Nuclear or X-radiation G01T 3/08 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/115 (20130101) H01L 31/1804 (20130101) H01L 31/1856 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09673448 — Electrodes, lithium-ion batteries, and methods of making and using same

US 09673448	Yushin et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Glenn Research Center (GLENN) NASA Shared Services Center (NSSC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York)
ASSIGNEE(S)	Sila Nanotechnologies Inc. (Alameda, California); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York)
ABSTRACT	Described herein are improved composite anodes and lithium-ion batteries made therefrom. Further described are methods of making and using the improved anodes and batteries. In general, the anodes include a porous composite having a plurality of agglomerated nanocomposites. At least one of the plurality of agglomerated nanocomposites is formed from a dendritic particle, which is a three-dimensional, randomly-ordered assembly of nanoparticles of an electrically conducting material and a plurality of discrete non-porous nanoparticles of a non-carbon Group 4A element or mixture thereof disposed on a surface of the dendritic particle. At least one nanocomposite of the plurality of agglomerated nanocomposites has at least a portion of its dendritic particle in electrical communication with at least a portion of a dendritic particle of an adjacent nanocomposite in the plurality of agglomerated nanocomposites.
FILED	Tuesday, October 14, 2014
APPL NO	14/513920
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/18 (20130101) H01B 1/24 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/137 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/587 (20130101) H01M 4/602 (20130101) H01M 4/625 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/12 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101)
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Department of Commerce (DOC)

09668825 — Dental and endodontic filling materials and methods

US 09668825	Chow et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	ADA Foundation (Chicago, Illinois)
ASSIGNEE(S)	ADA Foundation (Chicago, Illinois)
INVENTOR(S)	Laurence C. Chow (Potomac, Maryland); Shozo Takagi (Gaithersburg, Maryland)
ABSTRACT	Disclosed are endodontic filling materials and methods. A method for filling a dental root canal may include providing a hydrosetting filling material and inserting the hydrosetting filling material into the dental root canal, the material setting in the root canal to form a biocompatible filling. The hydrosetting filling material comprises a hydrogel former and a filler. The hydrogel former is at least one of a reactive organic hydrogel formers, an inorganic hydrogel formers, and a non-reactive organic hydrogel formers, and the filler is at least one of a self-hardening and a non-hardening filler. Plural filling material precursor compositions that collectively contain hydrogel formers and fillers may be provided.
FILED	Tuesday, July 21, 2015
APPL NO	14/805137
ART UNIT	1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 5/04 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 6/0038 (20130101)
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09670541 — Manipulation of microparticles in microfluidic systems

US 09670541	Mehta et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Advanced Technology Program (NIST-ATP)
APPLICANT(S)	Caliper Life Sciences, Inc. (Hopkinton, Massachusetts)
ASSIGNEE(S)	CALIPER LIFE SCIENCES, INC. (Hopkinton, Massachusetts)
INVENTOR(S)	Tammy Burd Mehta (San Jose, California); Anne R. Kopf-Sill (Portola Valley, California); J. Wallace Parce (Palo Alto, California); Andrea W. Chow (Los Altos, California); Luc J. Bousse (Los Altos, California); Michael R. Knapp (Palo Alto, California); Theo T. Nikiforov (San Jose, California); Steve Gallagher (Palo Alto, California)
ABSTRACT	An array of transportable particle sets is used in a microfluidic device for performing chemical reactions in the microfluidic device. The microfluidic device comprises a main channel and intersecting side channels, the main channel and side channels forming a plurality of intersections. The array of particle sets is disposed in the main channel, and the side channels are coupled to reagents. As the particle sets are transported through the intersections of the main channel and the side channels, reagents are flowed through the side channels into contact with each array member (or selected array members), thereby providing a plurality of chemical reactions in the microfluidic system.
FILED	Tuesday, August 11, 2015
APPL NO	14/823571
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0059 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00317 (20130101) B01J 2219/00459 (20130101) B01J 2219/00468 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/0668 (20130101) B01L 2400/043 (20130101) B01L 2400/0409 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/186 (20130101) C12Q 2527/125 (20130101) C12Q 2535/101 (20130101) C12Q 2563/173 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44756 (20130101) G01N 35/0098 (20130101) G01N 2035/00574 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115)
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09670591 — Defect reduction in seeded aluminum nitride crystal growth

US 09670591	Bondokov et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York)
ASSIGNEE(S)	CRYSTAL IS, INC. (Green Island, New York)
INVENTOR(S)	Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York)
ABSTRACT	Bulk single crystal of aluminum nitride (AlN) having an areal planar defect density ≦100 cm⁻². Methods for growing single crystal aluminum nitride include melting an aluminum foil to uniformly wet a foundation with a layer of aluminum, the foundation forming a portion of an AlN seed holder, for an AlN seed to be used for the AlN growth. The holder may consist essentially of a substantially impervious backing plate.
FILED	Wednesday, August 13, 2014
APPL NO	14/458825
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/00 (20130101) C30B 23/025 (20130101) Original (OR) Class C30B 29/403 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02389 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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Department of Veterans Affairs (DVA)

09668666 — System and method for reconstructing cardiac activation information

US 09668666	Narayan et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); Topera, Inc. (Menlo Park, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California); Ruchir Sehra (Scottsdale, Arizona)
ABSTRACT	In a system and method for reconstructing cardiac activation information, an analysis cardiac signal and a reference cardiac signal are accessed and processed to determine a first point of change in the analysis cardiac signal at which a derivative of the analysis cardiac signal diverges with respect to a derivative of the reference cardiac signal. The signals are processed to determine a second point of change in the analysis cardiac signal at which a different derivative of the analysis cardiac signal with respect to a different derivative of the reference cardiac signal. An activation onset time is assigned in the analysis cardiac signal at a point based on a mathematical association of the first point of change and the second point of change to define cardiac activation indicating a beat in the analysis cardiac signal.
FILED	Tuesday, November 17, 2015
APPL NO	14/944096
ART UNIT	3766 — Semiconductors/Memory
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0255 (20130101) A61B 5/0468 (20130101) A61B 5/0472 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/7207 (20130101) A61B 5/7278 (20130101)
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09668889 — Percutaneous osseointegrated prosthetic implant system

US 09668889	Holt et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	Brian Mueller Holt (Topanga, California); Kent N. Bachus (Salt Lake City, Utah); Sujee Jeyapalina (Salt Lake City, Utah); James Peter Beck (Salt Lake City, Utah); Roy Bloebaum (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Brian Mueller Holt (Topanga, California); Kent N. Bachus (Salt Lake City, Utah); Sujee Jeyapalina (Salt Lake City, Utah); James Peter Beck (Salt Lake City, Utah); Roy Bloebaum (Salt Lake City, Utah)
ABSTRACT	An implant system for securing a prosthesis to a selected bone of a subject including a stem and an abutment. The stem includes a porous region that promotes osseointegration of the selected bone following implantation of the stem. The abutment is secured to the stem and is configured for secure attachment to the prosthesis. The stem and the abutment include ultra-low friction and/or highly polished surfaces at select locations that inhibit bio-adhesion.
FILED	Wednesday, June 06, 2012
APPL NO	14/123719
ART UNIT	3738 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 2008/0046 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/78 (20130101) Original (OR) Class A61F 2/2814 (20130101) A61F 2002/3694 (20130101) A61F 2002/7887 (20130101) A61F 2002/30013 (20130101) A61F 2002/30332 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2270/0421 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09672718 — Nestable anti-ligative bed linen system and device

US 09672718	Shilts et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Steven J Shilts (San Diego, California); Brook Hjelm (Ramona, California)
ASSIGNEE(S)
INVENTOR(S)	Steven J Shilts (San Diego, California); Brook Hjelm (Ramona, California)
ABSTRACT	A nestable anti-ligative bed linen device and system comprising individual bed linen units wherein a plurality of such units may nest therein and be securely positioned in place on a mattress. Said individual bed linen unit of this system comprising a blanket attached to a cover sheet at a point of union at their common ends. Said union positioned towards the edge of said common ends to allow space for nesting. Said union positioned underneath a mattress by a given distance to allow multiple bed linen units to securely position on a mattress in nested form. The anti-ligative features include a union positioned at a location on said bed linen unit to prevent a lanyard from being formed. Other anti-ligative features include quilted thick tear resistant material and a built in pillow. Additional safety mechanisms are included such as a motion sensor and alarm.
FILED	Tuesday, March 31, 2015
APPL NO	14/675411
ART UNIT	2685 — Selective Communication
CURRENT CPC	Chairs; Sofas; Beds A47C 21/022 (20130101) A47C 31/105 (20130101) Household or Table Equipment A47G 9/02 (20130101) A47G 9/10 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) Original (OR) Class
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Small Business Administration (SBA)

09671507 — Solid-state neutron detector device

US 09671507	Bensaoula et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	University of Houston System (Houston, Texas)
ASSIGNEE(S)	UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S)	Abdelhak Bensaoula (Houston, Texas); David Starikov (Houston, Texas); Rajeev Pillai (Manvel, Texas)
ABSTRACT	The structure and methods of fabricating a high efficiency compact solid state neutron detector based on III-Nitride semiconductor structures deposited on a substrate. The operation of the device is based on absorption of neutrons, which results in generation of free carriers.
FILED	Tuesday, March 24, 2015
APPL NO	14/667409
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Measurement of Nuclear or X-radiation G01T 3/08 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/115 (20130101) H01L 31/1804 (20130101) H01L 31/1856 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09672293 — Systems and methods for automatically identifying and linking names in digital resources

US 09672293	Parker et al.
FUNDED BY	Department of Energy (DOE) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	Charles T. Parker (East Lansing, Michigan); Catherine M. Lyons (Edinburgh, United Kingdom); Gerald P. Roston (Saline, Michigan); George M. Garrity (Okemos, Michigan)
ASSIGNEE(S)	NAMESFORLIFE, LLC (East Lansing, Michigan)
INVENTOR(S)	Charles T. Parker (East Lansing, Michigan); Catherine M. Lyons (Edinburgh, United Kingdom); Gerald P. Roston (Saline, Michigan); George M. Garrity (Okemos, Michigan)
ABSTRACT	The present invention provides systems and methods for automatically identifying name-like-strings in digital resources, matching these name-like-string against a set of names held in an expertly curated database, and for those name-like-strings found in said database, enhancing the content by associating additional matter with the name, wherein said matter includes information about the names that is held within said database and pointers to other digital resources which include the same name and it synonyms.
FILED	Tuesday, January 12, 2010
APPL NO	12/685964
ART UNIT	2162 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/30864 (20130101) G06F 17/30887 (20130101) Original (OR) Class
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09673448 — Electrodes, lithium-ion batteries, and methods of making and using same

US 09673448	Yushin et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Glenn Research Center (GLENN) NASA Shared Services Center (NSSC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York)
ASSIGNEE(S)	Sila Nanotechnologies Inc. (Alameda, California); Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York)
ABSTRACT	Described herein are improved composite anodes and lithium-ion batteries made therefrom. Further described are methods of making and using the improved anodes and batteries. In general, the anodes include a porous composite having a plurality of agglomerated nanocomposites. At least one of the plurality of agglomerated nanocomposites is formed from a dendritic particle, which is a three-dimensional, randomly-ordered assembly of nanoparticles of an electrically conducting material and a plurality of discrete non-porous nanoparticles of a non-carbon Group 4A element or mixture thereof disposed on a surface of the dendritic particle. At least one nanocomposite of the plurality of agglomerated nanocomposites has at least a portion of its dendritic particle in electrical communication with at least a portion of a dendritic particle of an adjacent nanocomposite in the plurality of agglomerated nanocomposites.
FILED	Tuesday, October 14, 2014
APPL NO	14/513920
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/18 (20130101) H01B 1/24 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/137 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/587 (20130101) H01M 4/602 (20130101) H01M 4/625 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/12 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101)
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Department of Agriculture (USDA)

09668479 — Modulating germination of Paenibacillus larvae

US 09668479	Abel-Santos
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY (Las Vegas, Nevada)
ASSIGNEE(S)	The Board of Regents of the Nevada System of Higher Education on Behalf of the University of Nevada, Las Vegas (Las Vegas, Nevada)
INVENTOR(S)	Ernesto Abel-Santos (Las Vegas, Nevada)
ABSTRACT	Materials and methods for stimulating or inhibiting germination of Paenibacillus larvae spores, including methods for inhibiting P. larvae germination to reduce foulbrood in honey bees.
FILED	Friday, December 19, 2014
APPL NO	14/578091
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 31/08 (20130101) A01N 43/38 (20130101) Original (OR) Class
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09669004 — Daidzein analogs as treatment for cancer

US 09669004	Wang et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana); UNITED STATES DEPARTMENT OF AGRICULTURE (New Orleans, Louisiana); XAVIER UNIVERSITY OF LOUISIANA (New Orleans, Louisiana)
ASSIGNEE(S)	The Administrators of the Tulane Educational Fund (New Orleans, Louisiana); United States Department of Agriculture (New Orleans, Louisiana); Xavier University of Louisiana (New Orleans, Louisiana)
INVENTOR(S)	Guangdi Wang (New Orleans, Louisiana); Matthew E. Burow (New Orleans, Louisiana); Stephen M. Boue (New Orleans, Louisiana); Thomas E. Wiese (New Orleans, Louisiana); Quan Jiang (New Orleans, Louisiana)
ABSTRACT	Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.
FILED	Thursday, January 15, 2015
APPL NO	14/597252
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/353 (20130101) Original (OR) Class Heterocyclic Compounds C07D 311/38 (20130101) C07D 493/04 (20130101)
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National Security Agency (NSA)

09674025 — 4-level pulse amplitude modulation transmitter architectures utilizing quadrature clock phases

US 09674025	Dickson et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Timothy O. Dickson (Danbury, Connecticut); Bongjin Kim (Falcon Heights, Minnesota)
ABSTRACT	A four-level pulse amplitude modulation transmitter and corresponding method are provided. The transmitter includes a most significant bit processing section and a least significant bit processing section. The transmitter further includes at least one termination resistor connected to respective outputs of the processing sections to provide a transmitter output. Each of the processing sections include a set of retiming latches arranged in a parallel for aligning input parallel data and providing parallel aligned latched outputs responsive to one phase of a quarter-rate four-phase quadrature clock. Each of the processing sections further includes a serializer for serializing the parallel aligned latched outputs to provide a serialized output using quarter-rates of the quarter-rate four-phase quadrature clock. Each of the processing sections also include an output driver for driving the serialized output.
FILED	Tuesday, July 01, 2014
APPL NO	14/320736
ART UNIT	2632 — Digital Communications
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 27/364 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

D0789022 — Indoor parcel lockers

US D789022	Spears et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)	UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S)	Michael LeRoy Spears (Chantilly, Virginia); Joel L. Dewnandan (Bladenburg, Maryland); Donald Eugene Irwin (Fredericksburg, Virginia); Joram Shenhar (Fairfax, Virginia); William Albert Tartal (Baltimore, Maryland)
ABSTRACT
FILED	Friday, September 18, 2015
APPL NO	29/539926
ART UNIT	2912 — Design
CURRENT CPC	Miscellaneous D99/29
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 06, 2017.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20170606.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital