FedInvent™ Patents

Patent Details for Tuesday, June 13, 2017 

This page was updated on Monday, March 27, 2023 at 05:14 AM GMT

Department of Health and Human Services (HHS) 

US 09675040 Cleary et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Daniel Cleary (Portland, Oregon);  Carlos I. Fonck (Pasadena, California);  Henry A. Lester (South Pasadena, California);  Michael P. Walsh (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Daniel Cleary (Portland, Oregon);  Carlos I. Fonck (Pasadena, California);  Henry A. Lester (South Pasadena, California);  Michael P. Walsh (Pasadena, California)
ABSTRACT The disclosed device provides uniform illumination of variable intensity for a plant or animal container, e.g., a rodent cage, using infrared and broad spectrum light. Manual control or a timer can be provided. The device can mount on top of the container without need for substantial modification of the cage-or cage configuration.
FILED Tuesday, July 10, 2007
APPL NO 11/825912
ART UNIT 2875 — Optics
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 7/045 (20130101)

Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 1/031 (20130101) Original (OR) Class
A01K 63/06 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 37/0281 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 20/42 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 60/146 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675420 Higgins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) William E. Higgins (State College, Pennsylvania);  Jason D. Gibbs (State College, Pennsylvania)
ABSTRACT Methods and apparatus assist in planning routes through hollow, branching organs in patients to optimize subsequent endoscopic procedures. Information is provided about the organ and a follow-on endoscopic procedure associated with the organ. The most appropriate navigable route or routes to a target region of interest (ROI) within the organ are then identified given anatomical, endoscopic-device, or procedure-specific constraints derived from the information provided. The method may include the step of modifying the viewing direction at each site along a route to give physically meaningful navigation directions or to reflect the requirements of a follow-on live endoscopic procedure. An existing route may further be extended, if necessary, to an ROI beyond the organ. The information provided may include anatomical constraints that define locations or organs to avoid; anatomical constraints that confine the route within specific geometric locations; or a metric for selecting the most appropriate route. For example, the metric may define the closest route to the ROI such that the route satisfies all applicable anatomical, device, and procedural constraints.
FILED Monday, May 18, 2015
APPL NO 14/714836
ART UNIT 3768 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00009 (20130101)
A61B 1/00045 (20130101)
A61B 1/2676 (20130101)
A61B 6/032 (20130101)
A61B 6/466 (20130101)
A61B 6/469 (20130101)
A61B 34/10 (20160201) Original (OR) Class
A61B 2034/105 (20160201)
A61B 2034/107 (20160201)

Image Data Processing or Generation, in General
G06T 19/003 (20130101)
G06T 2207/30061 (20130101)
G06T 2210/41 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675550 Croyle et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Maria A. Croyle (Austin, Texas);  Jun Huk Choi (Austin, Texas);  Stephen Schafer (Austin, Texas)
ABSTRACT Vaccine compositions that may be administered to a subject via the buccal and/or sublingual mucosa are provided. Methods for administration and preparation of such vaccine compositions are also provided.
FILED Friday, January 25, 2013
APPL NO 13/750774
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/006 (20130101) Original (OR) Class
A61K 39/12 (20130101)
A61K 47/26 (20130101)
A61K 2039/541 (20130101)
A61K 2039/5256 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/04 (20130101)
C12N 7/00 (20130101)
C12N 2710/10343 (20130101)
C12N 2710/10351 (20130101)
C12N 2760/14134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675556 Akala et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Howard University (Washington, District of Columbia)
ASSIGNEE(S) Howard University (Washington, District of Columbia)
INVENTOR(S) Emmanuel Oyekanmi Akala (Mitchellville, Maryland);  Simeon Kolawole Adesina (Lanham, Maryland)
ABSTRACT The present invention is directed to a crosslinked or non-crosslinked polymer particle, wherein the crosslinked polymer particle comprises a copolymer of poly(alklyene glycol-graft-lactate) that is crosslinked by at least one hydrolysable monomer. Another embodiment of the present invention is a polymer particle comprising a crosslinked polymer particle that is a product of starting materials comprising (a) a hydrophilic monomer, (b) a hydrophobic monomer, and (c) a hydrolysable crosslinking agent. Another embodiment of the present invention is a polymer particle comprising, a crosslinked copolymer comprises structures represented by Formulas (I), (II), and (III), where Formulas (I), (II) and (III) are defined in the specification. Yet other embodiments of the present invention include a method of preparing a methacrylate terminated macromonomer, a method of preparing a crosslinking agent, and a method of preparing a therapeutic agent loaded nanosphere by dispersion polymerization.
FILED Thursday, December 18, 2014
APPL NO 14/575517
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1635 (20130101) Original (OR) Class
A61K 9/5153 (20130101)
A61K 31/337 (20130101)
A61K 31/704 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/06 (20130101)
B01J 13/16 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 15/00 (20130101)
B82Y 40/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/85 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2982 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675560 Ramamurthi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
ASSIGNEE(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
INVENTOR(S) Anand Ramamurthi (Pepper Pike, Ohio);  Balakrishnan Sivaraman (Westlake, Ohio);  Andrew Sylvester (Richmond, Virginia)
ABSTRACT Fibrinolytic nanoparticles including a polymeric core having a surface that is functionalized with a cationic amphiphilic compound, and a fibrinolytic agent dispersed within the core, are described herein. The fibrinolytic nanoparticles can be used in method of dissolving a blood clot in a subject by administering to the subject a therapeutically effective amount of fibrinolytic nanoparticles.
FILED Thursday, August 28, 2014
APPL NO 14/471616
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101)
A61K 9/5153 (20130101) Original (OR) Class
A61K 47/48023 (20130101)
A61K 47/48915 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675561 Bencherif et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Sidi A. Bencherif (Dorchester, Massachusetts);  Roger Warren Sands (Chicago, Illinois);  Sandeep T. Koshy (Boston, Massachusetts);  David J. Mooney (Sudbury, Massachusetts)
ABSTRACT The invention provides polymer compositions for cell and drug delivery.
FILED Tuesday, January 28, 2014
APPL NO 14/166689
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101)
A61K 9/7007 (20130101) Original (OR) Class
A61K 39/0011 (20130101)
A61K 39/39 (20130101)
A61K 47/36 (20130101)
A61K 47/42 (20130101)
A61K 2039/5152 (20130101)
A61K 2039/55522 (20130101)
A61K 2039/55561 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/50 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 2300/252 (20130101)
A61L 2300/258 (20130101)
A61L 2400/06 (20130101)

Compositions of Macromolecular Compounds
C08L 5/04 (20130101)
C08L 89/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675576 Golub et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York);  Chem-Master International, Inc. (East Setauket, New York)
ASSIGNEE(S) THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York);  CHEM-MASTER INTERNATIONAL, INC. (East Setauket, New York)
INVENTOR(S) Lorne M. Golub (Smithtown, New York);  Francis Johnson (Setauket, New York);  Galina I. Botchkina (Stony Brook, New York);  Iwao Ojima (Port Jefferson, New York)
ABSTRACT The present invention provides a method of inhibiting the growth of or promoting differentiation and destruction of cancer stem cells (CSCs) comprising contacting the cancer stem cells with a compound having the structure:
or a pharmaceutically acceptable salt thereof.
FILED Tuesday, November 24, 2015
APPL NO 14/950033
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/136 (20130101)
A61K 31/136 (20130101)
A61K 31/167 (20130101)
A61K 31/167 (20130101)
A61K 31/216 (20130101) Original (OR) Class
A61K 31/216 (20130101)
A61K 31/337 (20130101)
A61K 31/337 (20130101)
A61K 31/444 (20130101)
A61K 31/444 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675591 Wulff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Heike Wulff (Davis, California);  Nichole Coleman (Davis, California);  David Paul Jenkins (Davis, California)
ABSTRACT The present invention provides methods for treating seizure disorders. The method includes administering to a subject in need thereof 2-amino-6-trifluoromethylthio-benzothiazole, or a pharmaceutically acceptable salt thereof. Methods for the treatment of pain are also described.
FILED Friday, April 15, 2016
APPL NO 15/130796
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/428 (20130101) Original (OR) Class
A61K 31/428 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 277/82 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675602 Moss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S) THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S) Jonathan Moss (Chicago, Illinois);  Mark Lingen (Oak Park, Illinois);  Patrick A. Singleton (Chicago, Illinois);  Joe G. N. Garcia (Chicago, Illinois);  Chun-Su Yuan (Chicago, Illinois)
ABSTRACT The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
FILED Wednesday, August 21, 2013
APPL NO 13/972122
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/46 (20130101) Original (OR) Class
A61K 31/451 (20130101)
A61K 31/451 (20130101)
A61K 31/485 (20130101)
A61K 31/485 (20130101)
A61K 31/513 (20130101)
A61K 31/513 (20130101)
A61K 39/39558 (20130101)
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675607 Messersmith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Northwestern University (Evanston, Illinois);  The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania)
INVENTOR(S) Phillip B. Messersmith (Clarendon Hills, Illinois);  Iossif A. Strehin (Lincolnshire, Illinois);  Ellen Heber-Katz (Philadelphia, Pennsylvania)
ABSTRACT Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.
FILED Thursday, November 13, 2014
APPL NO 14/544003
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4745 (20130101) Original (OR) Class
A61K 47/48215 (20130101)
A61K 47/48784 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 65/333 (20130101)
C08G 65/33396 (20130101)
C08G 2210/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0071 (20130101)

Enzymes
C12Y 114/11002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675620 Shih et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Jean C. Shih (Beverly Hills, California);  Florence M. Hofman (Venice, California);  Thomas C. Chen (La Canada Flintridge, California)
ABSTRACT A pharmaceutical composition and method for treating brain cancer are provided. The method includes administering to a patient in need thereof an effective amount of one or more compounds that include moclobemide, clorgyline, clorgyline's Near-infra-red dye Monoamine Oxidase Inhibitor (NMI), and MHI 148-clorgyline, and their salt thereof. The composition and method are particularly effective in reducing the size of glioblastomas that are temozolomide (TMZ) resistant.
FILED Thursday, February 05, 2015
APPL NO 14/615416
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/15 (20130101)
A61K 31/15 (20130101)
A61K 31/135 (20130101)
A61K 31/135 (20130101)
A61K 31/137 (20130101)
A61K 31/137 (20130101)
A61K 31/138 (20130101)
A61K 31/138 (20130101)
A61K 31/352 (20130101)
A61K 31/352 (20130101)
A61K 31/357 (20130101)
A61K 31/357 (20130101)
A61K 31/366 (20130101)
A61K 31/366 (20130101)
A61K 31/381 (20130101)
A61K 31/381 (20130101)
A61K 31/405 (20130101)
A61K 31/405 (20130101)
A61K 31/495 (20130101)
A61K 31/495 (20130101)
A61K 31/4045 (20130101)
A61K 31/4188 (20130101)
A61K 31/5375 (20130101) Original (OR) Class
A61K 31/5375 (20130101)
A61K 45/06 (20130101)
A61K 49/16 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 209/24 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101)
C12N 2310/14 (20130101)
C12N 2310/531 (20130101)

Enzymes
C12Y 104/03004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675623 Gestwicki et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Jason E. Gestwicki (Moss Beach, California);  Kathryn McMenimen (South Hadley, Massachusetts);  Leah Makley (San Francisco, California)
ABSTRACT The invention provides inhibitors of α-crystallin aggregation and methods of using α-crystallin aggregation inhibitors to, e.g., treat or prevent cataracts in a subject having or at risk of developing cataracts. The invention further provides high throughput methods of screening compounds for modulation of protein thermal stability, the method comprising contacting a protein with each of a plurality of test compounds; and (b) measuring the melting transition (Tm) of the protein in the presence of each of the plurality of test compounds, wherein a compound that decreases or increases the apparent Tm by at least 2 standard deviations is identified as a pharmacological protein chaperone.
FILED Wednesday, July 17, 2013
APPL NO 13/944477
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 31/045 (20130101)
A61K 31/575 (20130101) Original (OR) Class
A61K 47/48969 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Steroids
C07J 9/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 33/68 (20130101)
G01N 2201/10 (20130101)
G01N 2333/4709 (20130101)
G01N 2500/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675633 Heimberger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Amy Heimberger (Houston, Texas);  Jun Wei (Houston, Texas)
ABSTRACT In some aspects, miRNA for the treatment of cancer are provided. In some embodiments, a miRNA (e.g., miR-124, miR-142, and/or miR-138) may be used to promote or enhance immune destruction of a cancer, or reduce the immune suppression of the cancer, in a subject. In other aspects, the miRNA may be used in, or in combination with, an adoptive immunotherapy.
FILED Friday, March 14, 2014
APPL NO 14/775667
ART UNIT 1674 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 31/7105 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675634 Machielse et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Vtesse, Inc. (Gaithersburg, Maryland)
ASSIGNEE(S) Vtesse Inc. (Gaithersburg, Maryland)
INVENTOR(S) Bernardus Nicolaas Machielse (North Potomac, Maryland);  Allan Darling (North Potomac, Maryland)
ABSTRACT This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C.
FILED Friday, October 07, 2016
APPL NO 15/288876
ART UNIT 1673 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/0019 (20130101)
A61K 9/0085 (20130101)
A61K 31/724 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675637 Gladwin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Mark T. Gladwin (Washington, District of Columbia);  Alan N. Schechter (Bethesda, Maryland);  David J. Lefer (Bronx, New York);  Rakesh P. Patel (Birmingham, Alabama);  Christian J. Hunter (Boston, Massachusetts);  Gordon G. Power (Redlands, California);  Daniel B. Kim-Shapiro (Winston-Salem, North Carolina);  Ryszard Pluta (Bethesda, Maryland);  Edward H. Oldfield (Philomont, Virginia);  Richard O. Cannon, III (Potomac, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, acting through Louisiana State University Health Sciences Center (Shreveport, Louisiana);  The UAB Research Foundation (Birmingham, Alabama);  Loma Linda University (Loma Linda, California);  Wake Forest University (Winston-Salem, North Carolina)
INVENTOR(S) Mark T. Gladwin (Washington, District of Columbia);  Alan N. Schechter (Bethesda, Maryland);  David J. Lefer (Bronx, New York);  Rakesh P. Patel (Birmingham, Alabama);  Christian J. Hunter (Boston, Massachusetts);  Gordon G. Power (Redlands, California);  Daniel B. Kim-Shapiro (Winston-Salem, North Carolina);  Ryszard Pluta (Bethesda, Maryland);  Edward H. Oldfield (Philomont, Virginia);  Richard O. Cannon, III (Potomac, Maryland)
ABSTRACT It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension. This discovery provides useful treatments to regulate a subject's blood pressure and blood flow, for example, by the administration of nitrite salts. Provided herein are methods of administering a pharmaceutically-acceptable nitrite salt to a subject, for treating, preventing or ameliorating a condition selected from: (a) ischemia-reperfusion injury (e.g., hepatic or cardiac or brain ischemia-reperfusion injury); (b) pulmonary hypertension (e.g., neonatal pulmonary hypertension); or (c) cerebral artery vasospasm.
FILED Friday, July 09, 2004
APPL NO 10/563683
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 33/00 (20130101) Original (OR) Class
A61K 33/00 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675641 Pelus et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Indiana University Research and Technology Corp. (Indianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) Louis M. Pelus (Indianapolis, Indiana);  Jonathan Hoggatt (Somerville, Massachusetts);  Pratibha Singh (Indianapolis, Indiana)
ABSTRACT This disclosure is directed to the methods of enhancing hematopoietic stem cells (HSPC) and progenitor cell (HSPC) engraftment procedure. Treatment in vivo of a HSPC donor with compounds that reduce PGE2 biosynthesis or PGE2 receptor antagonists alone, or in combination with other hematopoietic mobilization agents such as AMD3100 and G-CSF, increases the circulation of available HSPCs. Compounds that reduce the cellular synthesis of PGE2 include non-steroidal anti-inflammatory compounds such as indomethacin. Treatment ex vivo of HSPC with an effective amount of PGE2 or at least one of its derivatives such as 16,16-dimethyl prostaglandin E2 (dmPGE2), promotes HSPC engraftment. Similar methods may also be used to increase viral-mediated gene transduction efficacy into HSPC.
FILED Wednesday, March 04, 2015
APPL NO 14/638676
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/395 (20130101)
A61K 31/405 (20130101)
A61K 31/4035 (20130101)
A61K 31/4196 (20130101)
A61K 31/5415 (20130101)
A61K 35/14 (20130101) Original (OR) Class
A61K 35/28 (20130101)
A61K 35/50 (20130101)
A61K 35/51 (20130101)
A61K 38/193 (20130101)
A61K 2035/124 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/16 (20130101)
C12N 5/0647 (20130101)
C12N 9/0083 (20130101)
C12N 15/63 (20130101)
C12N 15/86 (20130101)
C12N 2501/02 (20130101)

Enzymes
C12Y 114/99001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675646 Bitar
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina)
ASSIGNEE(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S) Khalil Bitar (Winston-Salem, North Carolina)
ABSTRACT Methods of generating tubular, bioengineered, smooth muscle structures are disclosed as well as bioengineered tissue for tubular organ repair or replacement. The methods can include the steps of obtaining smooth muscle cells; culturing the muscle cells to form a smooth muscle cell construct of directionally oriented smooth muscle cells; disposing the smooth muscle cell construct around a tubular scaffold; and culturing construct and scaffold in a growth media until a smooth muscle cell structure is achieved. The step of obtain smooth muscle cells can further include obtaining autologous smooth muscle cells from a subject. In one preferred embodiment, the muscle cells can first be on a fibrin substrate to form a muscle construct, which is then disposed around a tubular scaffold, for example, a chitosan scaffold. The methods of the present invention can further include connecting two or more tubular structures together to form an elongate composite structure.
FILED Thursday, January 31, 2013
APPL NO 14/375818
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/04 (20130101)
A61F 2/08 (20130101)
A61F 2002/045 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/34 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/20 (20130101)
A61L 27/20 (20130101)
A61L 27/50 (20130101)
A61L 27/3826 (20130101)
A61L 27/3873 (20130101)
A61L 2430/30 (20130101)

Compositions of Macromolecular Compounds
C08L 5/08 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0623 (20130101)
C12N 5/0661 (20130101)
C12N 2501/999 (20130101)
C12N 2533/54 (20130101)
C12N 2533/72 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675649 Bode
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Lars Bode (San Diego, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Lars Bode (San Diego, California)
ABSTRACT The invention provides formulations comprising isolated Disialyllacto-N-tetraose (DSLNT) or variants, isomers, analogs and derivatives thereof.
FILED Friday, February 03, 2012
APPL NO 13/983624
ART UNIT 1673 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Fodder
A23K 10/18 (20160501)
A23K 20/163 (20160501)
A23K 40/10 (20160501)
A23K 50/00 (20160501)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 29/30 (20160801)
A23L 33/40 (20160801)
A23L 33/135 (20160801)

Shaping or Working of Foodstuffs, Not Fully Covered by a Single Other Subclass
A23P 10/28 (20160801)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/702 (20130101)
A61K 35/741 (20130101)
A61K 35/742 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
G01N 2400/00 (20130101)
G01N 2800/38 (20130101)
G01N 2800/065 (20130101)
G01N 2800/067 (20130101)
G01N 2800/7095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675662 Rothblum
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Lawrence Rothblum (Oklahoma City, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Lawrence Rothblum (Oklahoma City, Oklahoma)
ABSTRACT Compositions for inhibition of RNA Polymerase I include peptides of Rpa43. Methods of production and use thereof are also disclosed.
FILED Friday, December 02, 2011
APPL NO 13/309651
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101) Original (OR) Class

Peptides
C07K 2319/10 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675663 Roth et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Jack Roth (Houston, Texas);  David Stewart (Ottawa, Canada);  Charles Lu (Houston, Texas);  Ignacio I. Wistuba (Houston, Texas);  Shaoyu Yan (Pearland, Texas);  Maria I. Nunez (Houston, Texas)
ABSTRACT A method for predicting a subject's response to a TUSC2 therapy is provided. In particular, a subject's response is predicted based on the proportion of cancers cells that are apoptotic. Also provided is a method of treating a subject previously predicted to have a favorable response with a TUSC2 therapy. Methods for treating cancer by administration of a TUSC2 therapeutic in conjunction with an EGFR inhibitor and/or a protein kinase inhibitor are also disclosed. Kits and reagents for use in TUSC2 therapy are provided.
FILED Monday, September 08, 2014
APPL NO 14/480341
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 31/517 (20130101)
A61K 31/7088 (20130101)
A61K 31/7135 (20130101)
A61K 38/17 (20130101)
A61K 38/1709 (20130101) Original (OR) Class
A61K 39/3955 (20130101)
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 48/005 (20130101)
A61K 48/0033 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 16/2863 (20130101)
C07K 16/3023 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)
G01N 2510/00 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675667 Ribbeck et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Katharina Ribbeck (Cambridge, Massachusetts);  Nicole Lynn Kavanaugh (Cambridge, Massachusetts);  Julia Yin-Ting Co (Cambridge, Massachusetts);  Erica Shapiro (Cambridge, Massachusetts)
ABSTRACT A method of altering intercellular interactions between a combination of microorganisms includes contacting a combination of different species of microorganisms with at least one mucin. Isolated compositions include a combination of microorganisms and at least one mucin. One microorganism of the combination inhibits cell growth or promotes cell death of at least one other microorganism of a different species in the combination. The combination of microorganisms with the mucin results an increase in cell growth or a reduction in cell death, respectively, of the at least one other microorganism.
FILED Tuesday, February 09, 2016
APPL NO 15/018965
ART UNIT 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/02 (20130101)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 29/065 (20160801)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0014 (20130101)
A61K 9/20 (20130101)
A61K 9/0053 (20130101)
A61K 35/74 (20130101)
A61K 38/1735 (20130101) Original (OR) Class
A61K 47/42 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/16 (20130101)
C12N 1/20 (20130101)
C12N 1/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675679 Zorrilla et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Eric P. Zorrilla (San Diego, California);  Michael M. Meijler (Omer, Israel);  Kim D. Janda (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Eric P. Zorrilla (San Diego, California);  Michael M. Meijler (Omer, Israel);  Kim D. Janda (La Jolla, California)
ABSTRACT The invention features immunoconjugates for impeding weight gain and treating obesity in a subject. The immuno-conjugates comprise particular ghrelin polypeptides and a suitable carrier moiety.
FILED Wednesday, August 01, 2007
APPL NO 12/374908
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0005 (20130101) Original (OR) Class
A61K 2039/6081 (20130101)

Peptides
C07K 14/60 (20130101)
C07K 2319/31 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675687 Lu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Shan Lu (Hopkinton, Massachusetts);  Shixia Wang (Northborough, Massachusetts)
ABSTRACT Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV are disclosed. The compositions and methods described herein are for the use of a nucleic acid composition that encodes one or more different HIV envelope glycoproteins. The synthetic, codon-optimized DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV polypeptide compositions for inducing an immune response against HIV are also disclosed. Methods for using the polypeptide compositions before, at the same time as, and/or after administration of the DNA compositions are provided.
FILED Thursday, March 13, 2014
APPL NO 14/776682
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/21 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2039/53 (20130101)
A61K 2039/54 (20130101)
A61K 2039/70 (20130101)
A61K 2039/545 (20130101)
A61K 2039/575 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675688 Koelle et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
INVENTOR(S) David M. Koelle (Seattle, Washington);  Zhi Liu (Seattle, Washington);  Lawrence Corey (Mercer Island, Washington)
ABSTRACT A method of identifying an immunologically active antigen of a virus that attacks skin, as well as a method of enriching a population of lymphocytes for T lymphocytes that are specific to a virus that attacks skin. Also provided are HSV antigens and epitopes that are useful for the prevention and treatment of HSV infection that have been identified via the methods of the invention. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection.
FILED Monday, September 21, 2015
APPL NO 14/860623
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/245 (20130101) Original (OR) Class
A61K 2039/5158 (20130101)
A61K 2039/5256 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/16622 (20130101)
C12N 2710/16634 (20130101)
C12N 2710/24143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675689 Diamond et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
U.S. Public Health Service (USPHS)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Don Diamond (Glendora, California);  Zhongde Wang (Mount Pleasant, South Carolina)
ABSTRACT A vaccine comprising an immunologically effective amount of recombinant modified vaccinia Ankara (rMVA) virus which is genetically stable after serial passage and produced by a) constructing a transfer plasmid vector comprising a modified H5 (mH5) promoter operably linked to a DNA sequence encoding a heterologous foreign protein antigen, wherein the expression of said DNA sequence is under the control of the mH5 promoter; b) generating rMVA virus by transfecting one or more plasmid vectors obtained from step a) into wild type MVA virus; c) identifying rMVA virus expressing one or more heterologous foreign protein antigens using one or more selection methods for serial passage; d) conducting serial passage; e) expanding an rMVA virus strain identified by step d); and f) purifying the rMVA viruses from step e) to form the vaccine. One embodiment is directed to a fusion cytomegalovirus (CMV) protein antigen comprising a nucleotide sequence encoding two or more antigenic portions of Immediate-Early Gene-1 or Immediate-Early Gene-2 (IEfusion), wherein the antigenic portions elicit an immune response when expressed by a vaccine.
FILED Friday, November 08, 2013
APPL NO 14/075975
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/245 (20130101)
A61K 39/285 (20130101) Original (OR) Class
A61K 2039/5256 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2710/16134 (20130101)
C12N 2710/24143 (20130101)
C12N 2830/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675711 Suk et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Jung Soo Suk (Baltimore, Maryland);  Justin Scot Hanes (Baltimore, Maryland)
ABSTRACT Nanoparticles gene carriers, particularly nanoparticle gene carriers which exhibit increased rates of diffusion through cystic fibrosis (CF) mucus, as well as methods of making and using thereof, are described herein. The nanoparticle gene carriers are formed from a nucleic acid complexed to one or more biocompatible, polycationic polymers. The nanoparticle gene carriers also contain one or more mucus resistant polymers. In a particularly preferred embodiment, the nanoparticle gene carrier is a nanoparticle formed from one or more nucleic acids, PEI, and a mucus-resistant/diffusive graft copolymer composed of a PEI backbone functionalized by one or more PEG side chains. The nanoparticle gene carriers can efficiently diffuse through CF mucus, and can effectively serve as a vehicle to administer one or more nucleic acids to a patient suffering from CF.
FILED Monday, May 02, 2016
APPL NO 15/144077
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/48192 (20130101)
A61K 47/48215 (20130101)
A61K 48/0041 (20130101) Original (OR) Class
A61K 48/0075 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675713 Rao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Jianghong Rao (Sunnyvale, California);  Kanyi Pu (Mountain View, California);  Adam Shuhendler (Stanford, California)
ABSTRACT For whole animal in-situ and real-time imaging of inflammation, a dual-color fluorescent nanoprobe is provided for the detection of reactive oxygen and nitrogen species (RONS) in inflammatory microenvironments. The nanoprobes of the disclosure are a RONS-responsive energy transferring nanosystem of a fluorescent conjugated polymer core and a PEG-shell linked with RONS-sensing antennae as a FRET acceptor. These nanoprobes allow in vivo imaging of the entire process of inflammation from the release of local tissue distress signals, to the action of leukocytes and macrophages late in the process of inflammation, through to restitution, allowing in whole-body diagnosis and monitoring of inflammatory diseases.
FILED Thursday, June 27, 2013
APPL NO 13/928520
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0032 (20130101)
A61K 49/0054 (20130101)
A61K 49/0093 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675714 Mohapatra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Subhra Mohapatra (Lutz, Florida);  Chunyan Wang (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Subhra Mohapatra (Lutz, Florida);  Chunyan Wang (Tampa, Florida)
ABSTRACT Disclosed herein are theranostic nanoparticles configured for simultaneous delivery of a diagnostic moiety, drug moiety, and a gene therapy moiety. In one embodiment, the theranostic nanoparticles contain a super paramagnetic iron oxide chemotherapeutic loaded on a chitosan functionalized 2D graphene sheet with a gene therapy moiety attached to the surface of the chitosan functionalized 2D graphene sheet. Also disclosed are methods for making and administering theranositic nanoparticles configured for simultaneous delivery of a diagnostic moiety, drug moiety, and a gene therapy moiety.
FILED Friday, February 21, 2014
APPL NO 14/186845
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 48/0041 (20130101)
A61K 49/005 (20130101)
A61K 49/1881 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675803 Richter et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Claus-Peter Richter (Skokie, Illinois);  Petrina LaFaire (Chicago, Illinois);  Xiaodong Tan (Wilmette, Illinois)
ABSTRACT Aspects of the invention include system and method for transmitting neural data extracted from an electrical signal of a non-human mammal to a human. The system includes an electrode implantable into the animal auditory nerve, brainstem, or midbrain of the non-human mammal, configured to record the electrical signal of the non-human mammal, the electrical signal being in the form of sequences of pulses or pulse trains encoding frequency information of the non-human mammal, a processing device electrically coupled with the electrode, configured to process the electrical signal and convert the processed electrical signal into a digital signal, a transmitting device electrically coupled with the processing device, configured to transmit the digital signal, and a receiving device electrically coupled with the transmitting device, configured to receive the transmitted digital signal, convert the received digital signal into a sensory output perceptible to the human, and apply the sensory output to the human.
FILED Thursday, March 24, 2016
APPL NO 15/080075
ART UNIT 3766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0541 (20130101)
A61N 1/36032 (20130101) Original (OR) Class
A61N 1/37217 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675994 Schoenfisch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Mark H. Schoenfisch (Chapel Hill, North Carolina);  Ben Privett (Siler City, North Carolina);  Jae Ho Shin (Seoul, South Korea);  Jonghae Youn (Gyeonggi-do, South Korea)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Kwangwoon University Industry-Academic Collaboration Foundation (Seoul, South Korea)
INVENTOR(S) Mark H. Schoenfisch (Chapel Hill, North Carolina);  Ben Privett (Siler City, North Carolina);  Jae Ho Shin (Seoul, South Korea);  Jonghae Youn (Gyeonggi-do, South Korea)
ABSTRACT Superhydrophobic coatings and compositions and methods for preparing superhydrophobic coatings and compositions are described herein whereby the coatings and compositions are prepared under mild conditions, yet the methods are amenable to chemical functionalization of the coatings and components therein. The methods are useful for tuning and optimizing the physical properties of the coatings. In an embodiment, the coatings comprise nanostructured fluorinated silica colloids.
FILED Friday, June 01, 2012
APPL NO 14/122378
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/02 (20130101) Original (OR) Class

Non-metallic Elements; Compounds Thereof;
C01B 33/128 (20130101)
C01B 33/142 (20130101)
C01B 33/143 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 1/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676676 Hartung, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) John Hartung, Jr. (Evanston, Illinois);  Brendan L. Quigley (Pasadena, California);  Peter K. Dornan (Pasadena, California);  Robert H. Grubbs (South Pasadena, California)
ABSTRACT This invention relates generally to C—H activated ruthenium olefin metathesis catalyst compounds which are stereogenic at the ruthenium center, to their preparation, and the use of such catalysts in the metathesis of olefins and olefin compounds. In particular, the invention relates to the use of C—H activated ruthenium olefin metathesis catalyst compounds in Z-selective olefin metathesis reactions, enantio-selective olefin metathesis reactions, and enantio-Z-selective olefin metathesis reactions. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and industrial and fine chemicals chemistry.
FILED Wednesday, July 01, 2015
APPL NO 14/789848
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/2208 (20130101)
B01J 31/2278 (20130101)
B01J 2231/54 (20130101)
B01J 2231/543 (20130101)
B01J 2531/821 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 37/02 (20130101) Original (OR) Class
C07B 2200/09 (20130101)

Acyclic or Carbocyclic Compounds
C07C 6/04 (20130101)
C07C 6/04 (20130101)
C07C 15/50 (20130101)
C07C 29/32 (20130101)
C07C 29/32 (20130101)
C07C 33/025 (20130101)
C07C 67/293 (20130101)
C07C 67/293 (20130101)
C07C 67/293 (20130101)
C07C 67/293 (20130101)
C07C 67/343 (20130101)
C07C 67/343 (20130101)
C07C 67/475 (20130101)
C07C 67/475 (20130101)
C07C 69/63 (20130101)
C07C 69/78 (20130101)
C07C 69/145 (20130101)
C07C 69/593 (20130101)
C07C 69/608 (20130101)
C07C 2101/08 (20130101)
C07C 2101/14 (20130101)
C07C 2102/08 (20130101)
C07C 2531/22 (20130101)

Heterocyclic Compounds
C07D 207/46 (20130101)
C07D 211/94 (20130101)
C07D 317/12 (20130101)
C07D 471/04 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/1892 (20130101)
C07F 15/0046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676727 Plemper et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Emory University (Atlanta, Georgia);  Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia)
INVENTOR(S) Richard K. Plemper (Decatur, Georgia);  James P. Snyder (Atlanta, Georgia);  Aiming Sun (Atlanta, Georgia)
ABSTRACT This disclosure relates to antiviral compounds disclosed herein and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions. Typically, the pharmaceutical composition comprises a compound of formula I:
or salt, prodrug, or ester thereof wherein X, Y, and R1 and R10 to R13 are described herein.
FILED Thursday, July 07, 2016
APPL NO 15/204285
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/635 (20130101)
A61K 47/10 (20130101)
A61K 47/40 (20130101)

Heterocyclic Compounds
C07D 231/14 (20130101) Original (OR) Class
C07D 401/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676743 Coates et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Geoffrey W. Coates (Lansing, New York);  John W. Kramer (Ithaca, New York)
ABSTRACT Catalysts and methods for the carbonylation of epoxides to substituted 3-hydroxy-δ-lactones and β-lactones are disclosed.
FILED Wednesday, September 04, 2013
APPL NO 14/017803
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 309/30 (20130101) Original (OR) Class
C07D 311/96 (20130101)
C07D 405/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676744 Jiang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Complementary and Integrative Health (NCCIH)
National Cancer Institute (NCI)
APPLICANT(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
ASSIGNEE(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Qing Jiang (West Lafayette, Indiana)
ABSTRACT Long-chain carboxychromanol compounds useful for treating conditions associated with the need to inhibit cyclooxygenase-1, cyclooxygenase-2, and/or 5-lipoxygenase, and pharmaceutical formulations containing the compounds are provided herein.
FILED Friday, August 29, 2014
APPL NO 14/472799
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/12 (20130101)
A61K 31/12 (20130101)
A61K 31/343 (20130101)
A61K 31/343 (20130101)
A61K 31/353 (20130101)
A61K 31/353 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 311/72 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676763 Cunningham et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) James Cunningham (Wellesley, Massachusetts);  Kyungae Lee (Newton, Massachusetts);  Tao Ren (West Roxbury, Massachusetts);  Kartik Chandran (Brooklyn, New York)
ABSTRACT The present invention relates to compositions and methods for the treatment of infection by enveloped viruses, such as Ebola and Lassa fever viruses.
FILED Thursday, October 01, 2015
APPL NO 14/872577
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 311/29 (20130101)

Heterocyclic Compounds
C07D 207/08 (20130101)
C07D 207/09 (20130101)
C07D 207/14 (20130101)
C07D 211/58 (20130101)
C07D 243/08 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 405/04 (20130101)
C07D 417/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676771 Zhao et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Xue Zhi Zhao (Frederick, Maryland);  Steven Smith (Thurmont, Maryland);  Mathieu Metifiot (Saint Andre de Cubzac, France);  Barry Johnson (Chincoteague, Virginia);  Christophe Marchand (Silver Spring, Maryland);  Stephen H. Hughes (Smithsburg, Maryland);  Yves Pommier (Bethesda, Maryland);  Terrence R. Burke, Jr. (Bethesda, Maryland)
ABSTRACT A method of inhibiting drug-resistant HIV-1 integrase in a subject comprising administering to a subject in need thereof a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt or ester thereof, having a structure of:
wherein X is N, C(OH), or CH;
Y is H or OH;
each of Z1-Z5 is independently H or halogen;
R4 is H, OH, NH2, NHR8, NR8R9 or R8;
R5, R6, and R7 is each independently H, halogen, OR8, R8, NHR8, NR8R9, CO2R8, CONR8R9, SO2NR8R9, or R5 and R6 together with the carbon atoms to which R5 and R6 are attached form an optionally-substituted carbocycle or optionally-substituted heterocycle; and
R8 and R9 is each independently H, optionally-substituted alkyl, optionally-substituted alkenyl, optionally-substituted alkynyl, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted cycloalkylene, optionally-substituted heterocycle, optionally-substituted amide, optionally-substituted ester, or R8 and R9 together with the nitrogen to which R8 and R9 are attached form an optionally-substituted heterocycle.
FILED Tuesday, May 13, 2014
APPL NO 14/891309
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/4375 (20130101)
A61K 31/4375 (20130101)
A61K 31/4704 (20130101)
A61K 31/4704 (20130101)
A61K 31/5377 (20130101)
A61K 31/5377 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 215/58 (20130101)
C07D 215/60 (20130101)
C07D 471/04 (20130101) Original (OR) Class
C07D 491/147 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676779 Schwiebert et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) DISCOVERYBIOMED, INC. (Birmingham, Alabama)
ASSIGNEE(S) DiscoveryBiomed, Inc. (Birmingham, Alabama)
INVENTOR(S) Erik Schwiebert (Birmingham, Alabama);  John Streiff (Birmingham, Alabama);  John Dixon (Leicestershire, United Kingdom);  Hongwu Gao (Shanghai, China PRC)
ABSTRACT Novel CFTR corrector compounds that are effective in rescuing halide efflux, delF508-CFTR protein processing, and apical functional chloride ion transport in a cell are provided. Also provided are methods for treating protein folding disorders (e.g., cystic fibrosis). The methods include administering a CFTR corrector compound or pharmaceutically acceptable salt or prodrug thereof. Methods of rescuing halide efflux in a cell, correcting a processing defect of a delF508-CFTR protein in a cell, and correcting functional delF508-CFTR chloride channels in a cell are also provided.
FILED Wednesday, November 20, 2013
APPL NO 14/646063
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101)
C07D 487/04 (20130101) Original (OR) Class
C07D 498/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676782 Conn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) P. Jeffrey Conn (Nashville, Tennessee);  Craig W. Lindsley (Brentwood, Tennessee);  Kyle A. Emmitte (Spring Hill, Tennessee);  Julie L. Engers (Nashville, Tennessee);  Leah C. Konkol (Nashville, Tennessee)
ABSTRACT Described are negative allosteric modulators of metabotropic glutamate receptor 3 (mGlu3), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating depression, cognitive disorders, schizophrenia, Alzheimer's disease, or cancer in a subject. Exemplary negative allosteric modulators of metabotropic glutamate receptor 3 include pyrazolo[1,5-α]pyrazine compounds, such as those of the following formula:
FILED Friday, June 12, 2015
APPL NO 14/738222
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676788 Chain et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia);  University of Hawaii (Honolulu, Hawaii)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Health and Human Services (Washington, District of Columbia);  University of Hawaii (Honolulu, Hawaii)
INVENTOR(S) William J. Chain (Honolulu, Hawaii);  John A. Beutler (Union Bridge, Maryland);  David Fash (Honolulu, Hawaii);  William D. Figg (Fairfax, Virginia);  Zhenwu Li (West Haven, Connecticut);  Cody John Peer (Frederick, Maryland);  Joe William Ramos (Honolulu, Hawaii);  Florian J. Sulzmaier (San Diego, California)
ABSTRACT Disclosed is a compound of formula (I) or formula (II): (Formulas should be inserted here) wherein R1-R6 are as defined herein. Also disclosed are a pharmaceutical composition comprising such a compound and a method of treating or preventing cancer in a mammal in need thereof, comprising administering to the mammal a compound of formula (I) or formula (II).
FILED Thursday, February 05, 2015
APPL NO 15/116887
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/352 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 493/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676792 Gray et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Nathanael S. Gray (Boston, Massachusetts);  David Waller (Somerville, Massachusetts);  Hwan Guen Choi (Boston, Massachusetts);  Jinhua Wang (Boston, Massachusetts);  Xianming Deng (Brookline, Massachusetts)
ABSTRACT The present invention relates to novel pyrimido-diazepinone compounds, methods of modulating protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), LRKK2, EphA2, polo kinase 1, 2, 3, or 4, Ack1, Ack2, Abl, DCAMKL1, ABL1, Abl mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK1, ULK2, PLK4, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and the use of such compounds in the treatment of various diseases, disorders or conditions.
FILED Monday, March 17, 2014
APPL NO 14/775897
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/18 (20130101)
C07D 487/04 (20130101)
C07D 487/14 (20130101)
C07D 487/16 (20130101)
C07D 495/14 (20130101)
C07D 498/04 (20130101)
C07D 498/18 (20130101)
C07D 513/04 (20130101) Original (OR) Class

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676810 Anderson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Paul Anderson (Belmont, Massachusetts);  Pavel Ivanov (Brighton, Massachusetts);  Mohammed Emara (Newton, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Paul Anderson (Belmont, Massachusetts);  Pavel Ivanov (Brighton, Massachusetts);  Mohammed Emara (Newton, Massachusetts)
ABSTRACT Provided herein are neuroprotective molecules containing a sequence of 25-35 contiguous nucleotides that is at least 80% identical to a contiguous sequence between nucleotide 1 and nucleotide 50 of a mature human tRNA and at least four contiguous guanosine-containing nucleotides, where the sequence of 25-35 contiguous nucleotides contains a D-loop stem structure, the at least four contiguous guanosine-containing nucleotides are located at the 5′ end of the neuroprotective molecule, and the neuroprotective molecule contains at least one deoxyribonucleotide. Also provided are methods of inducing or increasing stress granule formation in a cell, decreasing protein translation in a cell, decreasing stress-induced cell death, or treating a neurological disorder associated with neuron death in a subject using at least one of these neuroprotective molecules.
FILED Friday, July 08, 2011
APPL NO 13/808863
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 2310/18 (20130101)
C12N 2310/531 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676812 Covey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Washington University (St. Louis, Missouri);  Sage Therapeutics, Inc. (Cambrige, Massachusetts)
ASSIGNEE(S) Washington University (St. Louis, Missouri);  Sage Therapeutics, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Douglas Covey (St. Louis, Missouri);  Albert Jean Robichaud (Ringoes, New Jersey)
ABSTRACT The present disclosure is generally directed to neuroactive 19-alkoxy-17-substituted steroids as referenced herein, and pharmaceutically acceptable salts thereof, for use as, for example, an anesthetic, and/or in the treatment of disorders relating to GABA function and activity. The present disclosure is further directed to pharmaceutical compositions comprising such compounds.
FILED Wednesday, December 18, 2013
APPL NO 14/652717
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Steroids
C07J 1/0011 (20130101)
C07J 1/0018 (20130101)
C07J 1/0029 (20130101) Original (OR) Class
C07J 5/0015 (20130101)
C07J 7/002 (20130101)
C07J 21/00 (20130101)
C07J 21/006 (20130101)
C07J 21/008 (20130101)
C07J 41/0005 (20130101)
C07J 41/0016 (20130101)
C07J 41/0094 (20130101)
C07J 51/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676816 Thallapuranam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
INVENTOR(S) Suresh Kumar Thallapuranam (Fayetteville, Arkansas);  Srinivas Jayanthi (Fayetteville, Arkansas);  Jacqueline Morris (Fayetteville, Arkansas);  Alicia Brown (Springdale, Arkansas);  David McNabb (Fayetteville, Arkansas);  Ralph Henry (Fayetteville, Arkansas)
ABSTRACT In one aspect, affinity tags for recombinant protein purification are described herein which, in some embodiments, can mitigate or overcome disadvantages of prior affinity tag systems. In some embodiments, for example, affinity tags described herein permit efficient elution of desired recombinant proteins with simplified solution systems, such as alkali metal salt solutions. An affinity tag described herein comprises an amino acid sequence including a repeating amino acid unit of BXXXBXX, wherein B is an amino acid selected from the group consisting of histidine, lysine and arginine and X is an amino acid selected from the group consisting of amino acids other than histidine, lysine and arginine.
FILED Tuesday, January 21, 2014
APPL NO 14/378230
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Separation
B01D 15/22 (20130101)
B01D 15/206 (20130101)
B01D 15/3809 (20130101)
B01D 69/08 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/286 (20130101)
B01J 20/28078 (20130101)

Peptides
C07K 1/22 (20130101) Original (OR) Class
C07K 14/00 (20130101)
C07K 2319/20 (20130101)
C07K 2319/50 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/6424 (20130101)

Enzymes
C12Y 304/21043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676818 Salunke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) University of Kansas (Lawrence, Kansas)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Deepak B. Salunke (Lawrence, Kansas);  Xiaoqiang Guo (Lawrence, Kansas);  Sunil A. David (Lawerence, Kansas)
ABSTRACT The present disclosure is directed to a novel class of toll-like receptor 2-agonistic (TLR2) lipopeptide compounds having specific structures, and synthetic methods of making the compounds. These compounds provide high potency of agonistic activities with human, other than murine, TLR2, and are useful as vaccine adjuvants. Vaccines are perhaps one of the most successful medical interventions against infectious disease.
FILED Friday, January 17, 2014
APPL NO 14/761805
ART UNIT 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 39/39 (20130101)
A61K 2039/55516 (20130101)

Peptides
C07K 5/0606 (20130101)
C07K 5/06086 (20130101) Original (OR) Class
C07K 14/705 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676823 Reshetnyak et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Rhode Island Council on Postsecondary Education (statutory successor to Board of Governors for Higher Education, State of Rhode Island and Providence Plantations) (Warick, Rhode Island);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) Rhode Island Council on Postsecondary Education (statutory successor to Board of Governors for Higher Education, State of Rhode Island and Providence Plantations) (Warwick, Rhode Island);  Yale University (New Haven, Connecticut)
INVENTOR(S) Yana K. Reshetnyak (South Kingstown, Rhode Island);  Oleg A. Andreev (South Kingstown, Rhode Island);  Ursula Lehnert (Richmond, United Kingdom);  Donald M. Engelman (New Haven, Connecticut)
ABSTRACT A polypeptide with a predominantly hydrophobic sequence long enough to span a membrane lipid bilayer as a transmembrane helix (TM) and comprising one or more dissociable groups inserts across a membrane spontaneously in a pH-dependant fashion placing one terminus inside cell. The polypeptide conjugated with various functional moieties delivers and accumulates them at cell membrane with low extracellular pH. The functional moiety conjugated with polypeptide terminus placed inside cell are translocated through the cell membrane in cytosol. The peptide and its variants or non-peptide analogs can be used to deliver therapeutic, prophylactic, diagnostic, imaging, gene regulation, cell regulation, or immunologic agents to or inside of cells in vitro or in vivo in tissue at low extracellular pH.
FILED Tuesday, April 22, 2014
APPL NO 14/258964
ART UNIT 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 47/48246 (20130101)

Peptides
C07K 14/001 (20130101) Original (OR) Class
C07K 14/215 (20130101)
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676824 Wei et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) GenVec, Inc. (Gaithersburg, Maryland)
ASSIGNEE(S) GenVec, Inc. (Gaithersburg, Maryland)
INVENTOR(S) Lisa Wei (Gaithersburg, Maryland);  Douglas E. Brough (Gaithersburg, Maryland);  Christopher Lazarski (Germantown, Maryland)
ABSTRACT Herpes Simplex Virus (HSV) antigens that elicit an HSV-specific immune response and can be used to treat or prevent HSV infection are provided. Nucleic acid sequences, polypeptides, vectors, and compositions, as well as methods to induce an immune response against HSV, treat or prevent HSV disease, induce a T cell response against HSV, and induce an antibody response against HSV also are provided.
FILED Thursday, May 16, 2013
APPL NO 14/403397
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/245 (20130101)
A61K 2039/53 (20130101)
A61K 2039/545 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/10043 (20130101)
C12N 2710/16622 (20130101)
C12N 2710/16634 (20130101)
C12N 2799/022 (20130101)
C12N 2800/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676836 Spudich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) John Lee Spudich (Houston, Texas);  Elena G. Govorunova (Houston, Texas);  Oleg A. Sineshchekov (Houston, Texas)
ABSTRACT Methods and compositions are used to identify and characterize new channelrhodopsins derived from algae and several of which are red-shifted. The rhodopsin domain of these red-shifted channelrhodopsins can be cloned and expressed in mammalian systems and used in optogenetic applications and as therapeutic agents. Also provided are methods and compositions for use in red-shifting the absorbance maxima of channelrhodopsins in order to improve their utility for use in vivo.
FILED Wednesday, July 01, 2015
APPL NO 14/789702
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/405 (20130101)
C07K 14/705 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/16 (20130101)
C12N 1/20 (20130101)
C12N 5/04 (20130101)
C12N 5/0602 (20130101)
C12N 5/0621 (20130101)
C12N 15/00 (20130101)
C12N 15/09 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676842 Bansal
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) NovelMed Therapeutics, Inc. (Cleveland, Ohio)
ASSIGNEE(S) NOVELMED THERAPEUTICS, INC. (Cleveland, Ohio)
INVENTOR(S) Rekha Bansal (Twinsburg, Ohio)
ABSTRACT A method of inhibiting alternative complement pathway activation in a mammal includes administering an amount of an antibody and/or fragment thereof that specifically binds to an epitope of the N terminus end of properdin effective to the inhibit alternative complement pathway in the subject.
FILED Wednesday, June 11, 2014
APPL NO 14/301872
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/34 (20130101)
C07K 2317/54 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676844 McAllister et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia);  THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S) Virginia Commonwealth University (Richmond, Virginia);  The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Janette M. McAllister (Hummelstown, Pennsylvania);  Jerome F. Strauss (Richmond, Virginia);  Neil D. Christensen (Harrisburg, Pennsylvania)
ABSTRACT Pharmaceutical compositions and methods for the treatment of DENND1 A. V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1 A. V2 and methods for using the same are provided.
FILED Wednesday, November 19, 2014
APPL NO 15/036119
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/24 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 2333/4706 (20130101)
G01N 2800/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676846 Dimitrov et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Dimiter S. Dimitrov (Frederick, Maryland);  Zhongyu Zhu (Frederick, Maryland);  Qi Zhao (Frederick, Maryland)
ABSTRACT Disclosed herein are human monoclonal antibodies that specifically bind both IGF-I and IGF-II with picomolar affinity and potently inhibit the IGF-IR signal transduction function. These antibodies are active in both an IgG and a scFv format. Bispecific forms of these antibodies are also disclosed. Nucleic acids encoding these antibodies, vectors including these nucleic acids, and host cells transformed with these vectors are also disclosed herein. Also disclosed are pharmaceutical compositions including these antibodies. Methods are provided for treating a subject with cancer and for inhibiting phosphorylation of the insulin-like growth factor-I receptor. Methods are also provided for diagnosing cancer.
FILED Friday, August 21, 2015
APPL NO 14/832803
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/22 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/31 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/57484 (20130101)
G01N 2333/475 (20130101)
G01N 2800/7028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676856 Chen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Lieping Chen (Hamden, Connecticut)
ABSTRACT Presented herein are therapeutic agents that modulate one or more immune functions and uses of such therapeutic agents in the prevention, treatment and management of diseases. In one aspect, the therapeutic agents modulate one or more signal transduction pathways induced by the binding of B7-H7 to B7-HrCR, or the binding of B7-H2 to either ICOS, CD28, or CTLA-4. In another aspect, the therapeutic agents modulate the binding of B7-H7 to B7-H7CR, or the binding of B7-H2 to either ICOS, CD28, or CTLA-4. The therapeutic agents can be used in the prevention, treatment and/or management of diseases in which it might be useful to modulate one or more immune functions (e.g., cancer, infectious disease, autoimmune disease, and transplantation rejection). In another aspect, presented herein are methods for identifying receptor-ligand interactions.
FILED Monday, August 11, 2014
APPL NO 14/456457
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)

Peptides
C07K 14/70521 (20130101)
C07K 14/70532 (20130101)
C07K 16/2818 (20130101)
C07K 16/2827 (20130101) Original (OR) Class
C07K 2316/95 (20130101)
C07K 2316/96 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/73 (20130101)
C07K 2317/74 (20130101)
C07K 2317/76 (20130101)
C07K 2319/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676857 Dimitrov et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Dimiter S. Dimitrov (Frederick, Maryland);  Tianlei Ying (Frederick, Maryland)
ABSTRACT Fc domains and CH3 domains are disclosed that bind the neonatal Fc (FcRn) receptor and are at least 99% monomeric. Monomeric Fc domain molecules and CH3 domain molecules are disclosed herein that include a monomeric Fc domain or a monomeric CH3 domain and an effector molecule. In some embodiments, the monomeric Fc or monomeric CH3 domain include amino acid substitutions and/or CDR insertions in the beta strands such that they specifically bind an antigen. Methods for using these monomeric Fc domains, monomeric CH3 domains, monomeric Fc domain molecules and CH3 domain molecules are also provided.
FILED Thursday, March 14, 2013
APPL NO 14/385133
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/005 (20130101)
C07K 16/00 (20130101)
C07K 16/283 (20130101) Original (OR) Class
C07K 16/1045 (20130101)
C07K 2317/52 (20130101)
C07K 2317/94 (20130101)
C07K 2317/524 (20130101)
C07K 2317/526 (20130101)
C07K 2317/565 (20130101)
C07K 2317/569 (20130101)
C07K 2319/30 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/16111 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676858 Bigner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DUKE UNIVERSITY (Durham, North Carolina);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
ASSIGNEE(S) Duke University (Durham, North Carolina);  The United States of America as represented by the secretary, Department of Health and Human Services (NIH) (Washington, District of Columbia)
INVENTOR(S) Darell Bigner (Mebane, North Carolina);  Chien-Tsun Kuan (Cary, North Carolina);  John Sampson (Durham, North Carolina);  Bryan Choi (Durham, North Carolina);  Ira H. Pastan (Potomac, Maryland);  Patrick C. Gedeon (Durham, North Carolina)
ABSTRACT We have constructed bispecific antibody engaging molecules which have one arm that specifically engages a tumor cell which expresses the human EGFRvIII mutant protein on its surface, and a second arm that specifically engages T cell activation ligand CD3. The engaging molecules are highly cytotoxic and antigen-specific. These may be used as therapeutic agents.
FILED Friday, June 07, 2013
APPL NO 14/406161
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/2809 (20130101)
C07K 16/2863 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/31 (20130101)
C07K 2317/56 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676867 Marasco et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute Inc. (Brookline, Massachusetts)
INVENTOR(S) Wayne A. Marasco (Wellesley, Massachusetts);  Agnes Lo (Jamaica Plain, Massachusetts);  Chen Xu (Beijing, China PRC)
ABSTRACT The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby.
FILED Wednesday, May 08, 2013
APPL NO 13/889924
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/2013 (20130101)
A61K 39/3955 (20130101)
A61K 51/1045 (20130101)
A61K 51/1075 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/30 (20130101)
C07K 16/40 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676870 Shi
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Guo-Ping Shi (Newton, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Guo-Ping Shi (Newton, Massachusetts)
ABSTRACT The technology described herein is directed to methods of treating cardiovascular and metabolic disorders.
FILED Monday, August 06, 2012
APPL NO 14/236544
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/4291 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676886 Moon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Joong Ho Moon (Weston, Florida);  Tereza Vokata (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Joong Ho Moon (Weston, Florida);  Tereza Vokata (Miami, Florida)
ABSTRACT A novel monomer design for the synthesis of PPE-type polymers containing conjugated segments of well-defined length connected by flexible linkers under Sonogashira reaction conditions is presented. The resulting polymers retain the photophysical properties of a fully conjugated PPE. The extent of incorporation of the flexible units along the backbone is governed by the comonomer feed ratio and can be varied in a statistically predictable fashion.
FILED Monday, August 10, 2015
APPL NO 14/821890
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 238/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677052 Silhavy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Thomas J. Silhavy (Belle Mead, New Jersey);  Marcin Grabowicz (Princeton, New Jersey);  Daniel Kahne (Brookline, Massachusetts);  Matthew Lebar (Mandeville, Louisiana);  Dorothee Andres (Potsdam, Germany)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Thomas J. Silhavy (Belle Mead, New Jersey);  Marcin Grabowicz (Princeton, New Jersey);  Daniel Kahne (Brookline, Massachusetts);  Matthew Lebar (Mandeville, Louisiana);  Dorothee Andres (Potsdam, Germany)
ABSTRACT The present disclosure generally relates to genetic engineering of bacteria. More particularly, the present disclosure describes genetic engineering of E. coli to create mutant O-antigen ligase, as well as novel lipopolysaccharide molecules resulting from that genetic engineering. Methods for using those novel molecules are also described.
FILED Friday, May 08, 2015
APPL NO 14/707718
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101)
A61K 2039/55516 (20130101)
A61K 2039/55572 (20130101)
A61K 2039/55583 (20130101)
A61K 2039/55594 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 13/06 (20130101)
C07H 15/04 (20130101)

Peptides
C07K 4/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/00 (20130101) Original (OR) Class
C12N 9/93 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677064 Edd et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
U.S. Public Health Service (USPHS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Jon F Edd (Arlington, Massachusetts);  Memhet Toner (Charlestown, Massachusetts);  Dino DiCarlo (Los Angeles, California);  Daniel Irimia (Charlestown, Massachusetts)
ABSTRACT Microfluidic devices and methods for the encapsulation of particles within liquid droplets are disclosed. The new methods and devices form 1-100 picoliter-size monodisperse droplets containing the particles, such as single cells, encapsulated in individual liquid droplets. The particles can be encapsulated in droplets of a fluid by passing a fluid containing the particles through a high aspect-ratio microchannel to order the particles in the fluid, followed by forming the fluid into droplets. The resulting fraction of the liquid droplets with a single particle (e.g., a cell) is higher than the corresponding fraction of single-particle liquid droplets predicted by Poisson statistics.
FILED Monday, June 29, 2015
APPL NO 14/754420
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 11/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677066 Rothberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) The University of Rochester (Rochester, New York)
ASSIGNEE(S) The University of Rochester (Rochester, New York)
INVENTOR(S) Lewis Rothberg (Pittsford, New York);  Barbara Stwertka (Rochester, New York)
ABSTRACT Compositions and methods for separating double-stranded nucleic acids out of a mixture comprising single-stranded nucleic acids and/or dNTPs and/or enzymes. The method uses spatially inhomogeneously functionalized nanoporous materials. For example, the compositions and methods of the present invention can be used to purify DNA amplification reaction products.
FILED Friday, May 29, 2015
APPL NO 14/725968
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/02 (20130101)
C08F 222/38 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1006 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 428/2982 (20150115)
Y10T 428/249978 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677068 Weissman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Jonathan Weissman (San Francisco, California);  Nicholas Ingolia (San Francisco, California);  Sina Ghaemmaghami (San Francisco, California);  John Newman (San Francisco, California)
ABSTRACT Methods are provided for, inter alia, detecting nucleic acid molecules resistant to degradation, such as a plurality of RNA molecules bound to a ribosome, using various technologies including deep sequencing.
FILED Friday, February 05, 2016
APPL NO 15/017214
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1034 (20130101)
C12N 15/1041 (20130101) Original (OR) Class
C12N 15/1093 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6809 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/08 (20130101)
C40B 50/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677070 Allison et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Omeros Corporation (Seattle, Washington);  University of Washington Through Its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) Omeros Corporation (Seattle, Washington);  University of Washington Through Its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Daniel S. Allison (Lake Forest Park, Washington);  W. Jason Cummings (Bellevue, Washington);  John B. Leppard (Mukilteo, Washington);  Nancy Maizels (Seattle, Washington);  Larry W. Tjoelker (Kirkland, Washington);  Christi L. Wood (Snohomish, Washington);  Munehisa Yabuki (Seattle, Washington)
ABSTRACT The disclosure relates generally to the targeting of genes to, and their integration into, an immunoglobulin (antibody) heavy chain locus. In particular, the methods described herein contemplate replacing the single rearranged heavy chain V, D, and J genes of a B cell lymphoma such as DT40 with independently rearranged VH-D-JH genes of chicken, in a system for generating immunoglobulin diversity. Also contemplated is replacement of the chicken VH-D-JH with rearranged VH-D-JH genes of other vertebrates including human in a system for generating immunoglobulin diversity, with the exception of any substitution disclosed and claimed in PCT application WO 2009/029315 A2. Also described is construction of a diverse chicken immunoglobulin heavy chain VDJ library in DT40 by homologous gene replacement of the single endogenous rearranged VDJ gene with a chicken VDJ repertoire using the described targeting vectors.
FILED Wednesday, March 13, 2013
APPL NO 13/802255
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 16/00 (20130101)
C07K 16/30 (20130101)
C07K 16/2863 (20130101)
C07K 2317/24 (20130101)
C07K 2317/92 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1082 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677072 Weiner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Louis M. Weiner (Washington, District of Columbia);  Rochelle E. Nasto (Washington, District of Columbia);  Robert Clarke (Washington, District of Columbia);  Erica Golemis (Philadelphia, Pennsylvania);  Ilya Serebriiskii (Rockledge, Pennsylvania)
ASSIGNEE(S) Georgetown University (Washington, District of Columbia)
INVENTOR(S) Louis M. Weiner (Washington, District of Columbia);  Rochelle E. Nasto (Washington, District of Columbia);  Robert Clarke (Washington, District of Columbia);  Erica Golemis (Philadelphia, Pennsylvania);  Ilya Serebriiskii (Rockledge, Pennsylvania)
ABSTRACT The invention relates to methods of inhibiting the growth or proliferation of a cell, the method comprising reducing the expression or activity of at least one gene in the cell selected from the group consisting of BLOC1S1, CDC2L1, CNOT1, DDX54, EIF3I, FANCG, FBP1, IER2, KIF1A, LCK, NR2F1, PNRC1, POLR2A, POLR2B, POLR2C, PRPF6, PSMB4, PSMC5, PSMD1, RPS2, SCNN1A, SF3A3, TAF2, TOB1 and TSC22D4.
FILED Friday, September 14, 2012
APPL NO 14/344773
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2320/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677075 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Colin Michael Calabrese (Evanston, Illinois);  William Morris (Evanston, Illinois)
ABSTRACT Disclosed herein are metal-ligand complexes containing polynucleotides, compounds for making the same, and methods of using the same.
FILED Wednesday, April 23, 2014
APPL NO 14/786569
ART UNIT 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7052 (20130101)
A61K 31/7088 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/581 (20130101)
C07F 15/02 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54346 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677085 Guye et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Patrick Guye (Cambridge, Massachusetts);  Ron Weiss (Newton, Massachusetts);  Mohammad Reza Ebrahimkhani (Somerville, Massachusetts)
ABSTRACT Aspects of the present disclosure are directed to methods and compositions for the production of heterogeneous tissue from human induced pluripotent stem (hiPS) cells.
FILED Tuesday, March 18, 2014
APPL NO 14/218426
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/4705 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0696 (20130101)
C12N 15/85 (20130101) Original (OR) Class
C12N 2510/00 (20130101)
C12N 2799/027 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677088 Nakai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Oregon Health and Science University (Portland, Oregon);  University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon);  University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Hiroyuki Nakai (West Linn, Oregon);  Kei Adachi (Portland, Oregon)
ABSTRACT Disclosed herein are adeno associated viral plasmids and viral vectors. Also disclosed are methods of using adeno associated viral vectors.
FILED Thursday, May 09, 2013
APPL NO 14/399428
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2710/10043 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677089 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Guangping Gao (Westborough, Massachusetts);  James M. Wilson (Glen Mills, Pennsylvania);  Mauricio R. Alvira (Philadelphia, Pennsylvania)
ABSTRACT Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles.
FILED Wednesday, March 30, 2016
APPL NO 15/084615
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/761 (20130101)
A61K 38/45 (20130101)
A61K 38/177 (20130101)
A61K 38/4846 (20130101)
A61K 48/00 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/705 (20130101)
C07K 14/755 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/644 (20130101)
C12N 9/1018 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14152 (20130101)
C12N 2830/008 (20130101)
C12N 2830/48 (20130101)
C12N 2830/85 (20130101)

Enzymes
C12Y 201/03003 (20130101)
C12Y 304/21022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677110 Cunningham
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Wayne State University (Detroit, Michigan)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Philip R. Cunningham (Troy, Michigan)
ABSTRACT The “instant evolution” system was initially developed in E. coli, primarily because of the ease with which this organism can be genetically manipulated. Because many of the functionally important regions of rRNA are conserved among bacteria, drug leads developed against conserved targets in the E. coli system may produce broad-spectrum anti-infectives. In order to develop a system to produce narrow-spectrum anti-infectives, herein we disclose methods for identifying functional mutant P. aeruginosa ribosomes suitable as drug targets and for identifying drug candidates that do not bind to the human 16S rRNA.
FILED Monday, June 22, 2015
APPL NO 14/746043
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101)
C12N 15/70 (20130101)
C12N 15/1034 (20130101)
C12N 15/1086 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/10 (20130101)
C12Q 1/18 (20130101) Original (OR) Class
C12Q 1/025 (20130101)
C12Q 1/6876 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/21 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677115 Naleway et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Marker Gene Technologies, Inc (Eugene, Oregon)
ASSIGNEE(S) Marker Gene Technologies, Inc. (Eugene, Oregon)
INVENTOR(S) John J Naleway (Eugene, Oregon);  Daniel J. Coleman (Corvallis, Oregon)
ABSTRACT The present invention relates to the visualization of acidic organelles based upon organelle enzyme activity. The organelle substrates of the invention are specific for enzyme activity of the organelle and label these organelles, such as lysosomes, rendering them visible and easily observed. Substrates of the present invention include substrates that produce a fluorescent signal. The fluorogenic acidic organelle enzyme substrates of this invention are designed to provide high fluorescence at low pH values and are derivatized to permit membrane permeation through both outer and organelle membranes of intact cells and can be used for staining cells at very low concentrations. They can be used for monitoring enzyme activity in cells at very low concentrations and are not toxic to living cells or tissues.
FILED Tuesday, May 14, 2013
APPL NO 13/986535
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/34 (20130101)
C12Q 1/44 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/531 (20130101)
G01N 33/573 (20130101)
G01N 33/582 (20130101)
G01N 33/5076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677138 Steiling et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts);  THE BRITISH COLUMBIA CANCER AGENCY BRANCH (Vancouver, Canada)
ASSIGNEE(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts);  THE BRITISH COLUMBIA CANCER AGENCY BRANCH (Vancouver, Canada)
INVENTOR(S) Katrina Steiling (Boston, Massachusetts);  Avrum Spira (Newton, Massachusetts);  Marc Lenberg (Brookline, Massachusetts);  Stephen Lam (Vancouver, Canada)
ABSTRACT A novel set of 98 genes expressed in the respiratory tract epithelium that serve as biomarkers for measuring chronic obstructive pulmonary disease (COPD) activity are provided. Methods of classifying the (COPD) status of a subject are provided. Systems for expression-based classification of COPD disease status are provided. Methods of treating COPD are also provided, among other things.
FILED Monday, May 20, 2013
APPL NO 14/402607
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/46 (20130101)
A61K 31/53 (20130101)
A61K 31/56 (20130101)
A61K 31/58 (20130101)
A61K 31/137 (20130101)
A61K 31/198 (20130101)
A61K 31/357 (20130101)
A61K 31/522 (20130101)
A61K 31/575 (20130101)
A61K 31/5377 (20130101)
A61K 38/06 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677989 Sklar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Larry A. Sklar (Albuquerque, New Mexico);  Bruce Edwards (Albuquerque, New Mexico);  Frederick Kuckuck (Emery, South Dakota)
ABSTRACT The present invention, provides a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a plurality of respective source wells into a fluid flow stream; means for introducing a separation gas between each of the plurality of samples in the fluid flow stream; and means for selectively analyzing each of the plurality of samples for the particles. The present invention also provides a flow cytometry method employing such an apparatus.
FILED Tuesday, January 26, 2016
APPL NO 15/006817
ART UNIT 1678 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5085 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1404 (20130101)
G01N 15/1436 (20130101) Original (OR) Class
G01N 15/1459 (20130101)
G01N 21/6428 (20130101)
G01N 21/6486 (20130101)
G01N 35/085 (20130101)
G01N 35/0099 (20130101)
G01N 35/1095 (20130101)
G01N 2015/0065 (20130101)
G01N 2015/149 (20130101)
G01N 2015/1006 (20130101)
G01N 2015/1402 (20130101)
G01N 2015/1413 (20130101)
G01N 2015/1477 (20130101)
G01N 2021/6439 (20130101)
G01N 2201/06113 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 436/2575 (20150115)
Y10T 436/117497 (20150115)
Y10T 436/118339 (20150115)
Y10T 436/119163 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678007 Backman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Vadim Backman (Chicago, Illinois);  Ji Yi (Evanston, Illinois)
ABSTRACT A method and system to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT) is disclosed. Tissue is modeled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. By measuring optical quantities of tissue (including the scattering power of the OCT spectrum, the reflection albedo α defined as the ratio of scattering coefficient μs, and the backscattering coefficient μb), the RI correlation function can be inversely deduced and the full set of optical scattering properties can be obtained.
FILED Friday, October 12, 2012
APPL NO 13/651196
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/4795 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678060 Rodriguez et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Raymond Rodriguez (Davis, California);  Alfredo F. Galvez (West Sacramento, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Raymond Rodriguez (Davis, California);  Alfredo F. Galvez (West Sacramento, California)
ABSTRACT Methods are provided for screening a test compound for anti-neoplastic activity by providing a test compound to a cancer cell and measuring the acetylation of Lysine 16 of the N-terminal tail of histone H4. Methods are also provided for using a test compound for staging a cancer tissue and for measuring the degree of the test compound's anti-neoplastic activity upon a cancer tissue by providing a test compound to a cancer tissue sample and measuring the degree of methylation of nucleotides within the 5′ region in the cancer tissue sample.
FILED Friday, October 10, 2008
APPL NO 12/682892
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/5011 (20130101) Original (OR) Class
G01N 33/6875 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678074 Prokunina et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Liudmila Prokunina (Rockville, Maryland);  Thomas R. O'Brien (Potomac, Maryland);  Brian Muchmore (Potomac, Maryland);  Raymond P. Donnelly (Damascus, Maryland);  Patricia A. Porter-Gill (Little Rock, Arkansas)
ABSTRACT The invention is related to identification of an interferon-analog (IFNL4) protein and genetic association with spontaneous clearance of HCV infection and response to treatment for HCV infection.
FILED Thursday, March 14, 2013
APPL NO 14/388293
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/555 (20130101)
C07K 16/249 (20130101)
C07K 2317/76 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/707 (20130101)
C12Q 1/6883 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101) Original (OR) Class
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678077 Rubin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Mark A. Rubin (New York, New York);  Juan Miguel Mosquera (New York, New York);  Kyung Park (Stamford, Connecticut);  Ya-Lin Chiu (Island Park, New York);  Francesca Demichelis (New York, New York)
ABSTRACT This invention relates to a triple immunostaining assay (ERG/TFF3/HMWCK) for sensitive and specific detection of prostate cancer. Positive staining for at least one of ERG or TFF3 combined with negative staining of HMWCK in a sample such as prostate tissue sample is indicative of cancer.
FILED Wednesday, May 15, 2013
APPL NO 14/401184
ART UNIT 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/18 (20130101)
C07K 16/26 (20130101)
C07K 16/32 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57434 (20130101) Original (OR) Class
G01N 2333/47 (20130101)
G01N 2333/4742 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678084 Pichichero et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Michael Pichichero (Rochester, New York);  Kyle Liu (Rochester, New York)
ASSIGNEE(S) Rochester General Hospital Research Institute (Rochester, New York)
INVENTOR(S) Michael Pichichero (Rochester, New York);  Kyle Liu (Rochester, New York)
ABSTRACT Compositions and methods related to diagnosis of ear infections and acute otitis media.
FILED Monday, June 04, 2012
APPL NO 13/488293
ART UNIT 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101) Original (OR) Class
G01N 2333/52 (20130101)
G01N 2333/5428 (20130101)
G01N 2333/70525 (20130101)
G01N 2800/14 (20130101)
G01N 2800/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678088 Whitesides et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Defense Science and Engineering Graduate Fellowship (NDSEG)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Children's Medical Center Corporation (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Children's Medical Center Corporation (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) George M. Whitesides (Newton, Massachusetts);  Ashok A. Kumar (Medford, Massachusetts);  Jonathan W. Hennek (Somerville, Massachusetts);  Caeul Lim (Boston, Massachusetts);  Yovany Moreno (Cambridge, Massachusetts);  Charles R. Mace (Auburn, New York);  Manoj T. Duraisingh (Cambridge, Massachusetts);  Matthew R. Patton (Cambridge, Massachusetts);  Si-yi Ryan Lee (Cambridge, Massachusetts);  Gaetana D'Alesio-Spina (Cambridge, Massachusetts);  Carlo Brugnara (Boston, Massachusetts);  Thomas P. Stossel (Boston, Massachusetts)
ABSTRACT An aqueous multi-phase system for diagnosis of sickle cell disease is described, including two or more phase-separated phases including: a first aqueous phase including a first phase component and having a first density between about 1.025 g/cm3 and about 1.095 g/cm3; and a second aqueous phase including a second phase component and having a second density between about 1.100 g/cm3 and about 1.140 g/cm3; wherein the first density is lower than the second density; and each of the first and second phase components include at least one polymer.
FILED Monday, April 28, 2014
APPL NO 14/785980
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/05 (20130101)
G01N 33/80 (20130101) Original (OR) Class
G01N 33/491 (20130101)
G01N 2015/003 (20130101)
G01N 2015/0073 (20130101)
G01N 2015/0076 (20130101)
G01N 2800/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678089 Montgomery
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) BloodCenter Research Foundation (Milwaukee, Wisconsin);  The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S) BLOOD CENTER RESEARCH FOUNDATION (Milwaukee, Wisconsin);  THE MEDICAL COLLEGE OF WISCONSIN, INC. (Milwaukee, Wisconsin)
INVENTOR(S) Robert Montgomery (Cedarburg, Wisconsin)
ABSTRACT Methods and kits for measuring levels of von Willebrand factor function in a sample without using a platelet aggregation agonist, such as ristocetin, comprising recombinant glycoprotein Ibα having a combination of G233V, D235Y and M239V mutations and an agent to detect a complex between the recombinant glycoprotein Ibα and von Willebrand factor.
FILED Monday, September 15, 2014
APPL NO 14/485926
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/745 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/86 (20130101) Original (OR) Class
G01N 33/554 (20130101)
G01N 33/5008 (20130101)
G01N 2333/47 (20130101)
G01N 2333/705 (20130101)
G01N 2333/755 (20130101)
G01N 2800/224 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678105 Gimzewski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) James K. Gimzewski (Topanga, California);  Sarah E. Cross (El Granada, California);  Yusheng Jin (North Hills, California);  Jianyu Rao (Culver City, California)
ABSTRACT Described herein is the analysis of nanomechanical characteristics of cells. In particular, changes in certain local nanomechanical characteristics of ex vivo human cells can correlate with presence of a human disease, such as cancer, as well as a particular stage of progression of the disease. Also, for human patients that are administered with a therapeutic agent, changes in local nanomechanical characteristics of ex vivo cells collected from the patients can correlate with effectiveness of the therapeutic agent in terms of impeding or reversing progression of the disease. By exploiting this correlation, systems and related methods can be advantageously implemented for disease state detection and therapeutic agent selection and monitoring.
FILED Friday, January 03, 2014
APPL NO 14/146961
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 35/00 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 20/00 (20130101)
G01Q 30/14 (20130101)
G01Q 30/025 (20130101) Original (OR) Class
G01Q 60/366 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678189 Mekkaoui
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Choukri Mekkaoui (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Choukri Mekkaoui (Boston, Massachusetts)
ABSTRACT Systems and methods are provided for mapping myocardial tissue architecture based on diffusion tensor imaging (DTI). A set of eigenvectors is derived from diffusion tensor data, where each eigenvector describes the diffusion of spins along one of the Cartesian directions. A radial coordinate axis and a circumferential plane are determined based on anatomical information of the subject, such as from an image depicting the epicardial surface of the subject's heart, A longitudinal coordinate axis and a circumferential coordinate axis are determined based on the radial coordinate axis and circumferential plane, A fiber architecture matrix (FAM) is then computed for locations in the subject's heart based on projecting the set of eigenvectors onto a local coordinate system defined by the circumferential, radial, and longitudinal axes, Maps that represent myocardial tissue architecture can then be generated using the FAM for locations within the subject's heart.
FILED Thursday, April 03, 2014
APPL NO 14/781637
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0044 (20130101)
A61B 5/055 (20130101)
A61B 2576/023 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5602 (20130101) Original (OR) Class
G01R 33/56341 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101)
G06T 11/003 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/30048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679113 Hanina et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) AIC Innovations Group, Inc. (New York, New York)
ASSIGNEE(S) AIC Innovations Group, Inc. (New York, New York)
INVENTOR(S) Adam Hanina (New York, New York);  Gordon Kessler (Mt. Kisco, New York);  Lei Guan (Harrison, New Jersey)
ABSTRACT A medication management system is described that is operable to determine whether a user is actually following a protocol, provide additional assistance to a user, starting with instructions, video instructions, and the like, and moving up to contact from a medication administrator if it is determined that the user would need such assistance in any medical adherence situation, including clinical trial settings, home care settings, healthcare administration locations, such as nursing homes, clinics, hospitals and the like. Suspicious activity on the part of a patient or other user of the system is identified and can be noted to a healthcare provider or other service provider where appropriate.
FILED Wednesday, June 10, 2015
APPL NO 14/735394
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1128 (20130101)
A61B 5/4833 (20130101)

Electric Digital Data Processing
G06F 19/3456 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00 (20130101)
G06K 9/00771 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/22 (20130101)

Pictorial Communication, e.g Television
H04N 7/183 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679341 Kocis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina At Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Keith C. Kocis (Chapel Hill, North Carolina);  Daniel J. Kocis, Jr. (Manorville, New York)
ABSTRACT A method for evaluating a hospital patient's risk of mortality includes collecting data from physiologic signals generated by patient monitors, physiologic signals of organ function, and demographic information for a patient. A measure of the variability of at least one of the physiologic signals is determined. Data and the measure of variability are analyzed to determine whether a value for a particular physiologic or demographic variable falls within a critical interval for the variable that indicates that the value is predictive of mortality or survival. Each time a value for a physiological or demographic variable for the patient falls within a critical interval, the occurrence of an event for the patient is recorded. The number of events for the patient is counted over a time period. Output perceptible by human user that indicates the patient's risk of mortality or likelihood of survival is generated based on the count.
FILED Wednesday, December 19, 2012
APPL NO 13/721010
ART UNIT 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Electric Digital Data Processing
G06F 19/345 (20130101)
G06F 19/3431 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 50/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679409 Black et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Brown University (Providence, Rhode Island)
ASSIGNEE(S) Brown University (Providence, Rhode Island)
INVENTOR(S) Michael J. Black (Tuebingen, Germany);  Peng Guan (Mountain View, California)
ABSTRACT Systems, methods, and computer-readable storage media for simulating realistic clothing. The system generates a clothing deformation model for a clothing type, wherein the clothing deformation model factors a change of clothing shape due to rigid limb rotation, pose-independent body shape, and pose-dependent deformations. Next, the system generates a custom-shaped garment for a given body by mapping, via the clothing deformation model, body shape parameters to clothing shape parameters. The system then automatically dresses the given body with the custom-shaped garment.
FILED Friday, February 15, 2013
APPL NO 14/372140
ART UNIT 2614 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 17/5009 (20130101)
G06F 2217/32 (20130101)

Image Data Processing or Generation, in General
G06T 17/00 (20130101) Original (OR) Class
G06T 19/20 (20130101)
G06T 2210/16 (20130101)
G06T 2219/2016 (20130101)
G06T 2219/2021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680693 Barford et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Paul R. Barford (Madison, Wisconsin);  Jeffery Thomas Kline (Madison, Wisconsin);  Sangnam Nam (Madison, Wisconsin);  David John Plonka (Madison, Wisconsin);  Amos Ron (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Paul R. Barford (Madison, Wisconsin);  Jeffery Thomas Kline (Madison, Wisconsin);  Sangnam Nam (Madison, Wisconsin);  David John Plonka (Madison, Wisconsin);  Amos Ron (Madison, Wisconsin)
ABSTRACT A network anomaly detector evaluates two complementary measurements of network statistics, a time variation and correlation among those statistics, to provide an extremely robust detection of network anomalies. In one embodiment, the variability and correspondence are compared against historically derived thresholds to provide for a system that accommodates to local network conditions and evolving network qualities.
FILED Thursday, November 29, 2007
APPL NO 12/516766
ART UNIT 2468 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/064 (20130101) Original (OR) Class
H04L 41/142 (20130101)
H04L 43/16 (20130101)
H04L 43/045 (20130101)
H04L 63/1425 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 09675572 Lewis
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Michael Lewis (Rockville, Maryland)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S) Michael Lewis (Rockville, Maryland)
ABSTRACT The invention encompasses intravenous pharmaceutical compositions containing omega-3 fatty acids and methods of treating traumatic brain injury, traumatic spinal cord injury and/or stroke using these pharmaceutical compositions.
FILED Friday, April 22, 2011
APPL NO 13/637239
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/107 (20130101)
A61K 31/201 (20130101)
A61K 31/201 (20130101)
A61K 31/202 (20130101) Original (OR) Class
A61K 31/202 (20130101)
A61K 47/14 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675577 D'Agostino et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Dominic Paul D'Agostino (Tampa, Florida);  Patrick Arnold (Champaign, Illinois);  Shannon Kesl (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Dominic Paul D'Agostino (Tampa, Florida);  Patrick Arnold (Champaign, Illinois);  Shannon Kesl (Tampa, Florida)
ABSTRACT Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.
FILED Monday, September 21, 2015
APPL NO 14/860092
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 2/52 (20130101)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/19 (20130101)
A61K 31/20 (20130101)
A61K 31/20 (20130101)
A61K 31/22 (20130101)
A61K 31/22 (20130101)
A61K 31/23 (20130101) Original (OR) Class
A61K 31/23 (20130101)
A61K 31/047 (20130101)
A61K 31/047 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675684 Schmaljohn
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by The Secretary of The Army (Washington, District of Columbia)
INVENTOR(S) Connie Schmaljohn (Middletown, Maryland)
ABSTRACT A synthetic, codon-optimized Hantaan virus (HTNV) full-length M gene open reading frame that consists of a unique nucleotide sequence encoding HTNV proteins. This synthetic gene was cloned into a plasmid to form the first optimized HTNV full-length M gene that elicits neutralizing antibodies in animals when delivered in combination with a similarly optimized Puumala virus (PUUV) DNA vaccine. The invention obviates the need for an extraneous gene sequence that was previously required for expression of the non-optimized HTNV gene. The synthetic gene is engineered into a molecular vaccine system to prevent hemorrhagic fever with renal syndrome (HFRS) caused by infection with HTNV, SEOV, or DOBV. Alternatively, it can be combined with the optimized PUUV DNA vaccine to protect against HFRS caused by any hantavirus.
FILED Thursday, September 24, 2015
APPL NO 14/756608
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0021 (20130101)
A61K 9/0073 (20130101)
A61K 9/5115 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/70 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/12122 (20130101)
C12N 2760/12134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676227 Frantz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Jesse A. Frantz (Landover, Maryland);  Jason D. Myers (Alexandria, Virginia);  Robel Y. Bekele (Washington, District of Columbia);  Jasbinder S. Sanghera (Ashburn, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jesse A. Frantz (Landover, Maryland);  Jason D. Myers (Alexandria, Virginia);  Robel Y. Bekele (Washington, District of Columbia);  Jasbinder S. Sanghera (Ashburn, Virginia)
ABSTRACT A method for forming a wet-etchable, sacrificial lift-off layer or layers compatible with high temperature processing, a sacrificial layer, defined as consisting of a single film of one material or multiple films of multiple materials, that can tolerate high temperatures, is deposited on a substrate, called the original substrate, by sputtering or another suitable technique (e.g. evaporation, pulsed laser deposition, wet chemistry, etc.). Intermediate steps result in a lift-off layer attached to the lift-off substrate, that allow for separating the product from the original substrate.
FILED Friday, March 07, 2014
APPL NO 14/201009
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Producing Decorative Effects; Mosaics; Tarsia Work; Paperhanging
B44C 1/227 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02002 (20130101)
H01L 31/1896 (20130101)
H01L 31/03928 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/541 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676317 Holz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Kevin Holz (San Diego, California);  Aaron Burmeister (San Diego, California);  Abraham Hart (San Diego, California);  Narek Pezeshkian (Glendale, California);  Hoa G. Nguyen (San Diego, California)
ABSTRACT A system includes a remotely-operated ground vehicle having first and second lift members, a first lift mechanism coupled to the first lift member, and a second lift mechanism coupled to the second lift member, where the first and second lift mechanisms are positioned at different angles with respect to a ground surface. The first and second lift members may be positioned at opposite sides of a front end of the vehicle and may be controlled by a single motor. The lift mechanisms may have a body portion including first and second prongs separated by an opening, with a plurality of magnets embedded within the body portion near the intersection of the first and second prongs. A communication relay may be secured to each lift mechanism via the opening and a magnetic coupling between the magnets embedded within the body portion and magnets embedded within the communication relay.
FILED Monday, June 22, 2015
APPL NO 14/746712
ART UNIT 3652 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 5/00 (20130101)

Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects
B60P 1/54 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676625 Petrie et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Mark A. Petrie (Santa Clara, California);  David Stout (Palo Alto, California);  Paul E. Penwell (Sausalito, California);  Sigridur Suman (Hayward, California);  Allen Dodge (Newark, California)
ASSIGNEE(S) Ardica Technologies, Inc. (San Francisco, California)
INVENTOR(S) Mark A. Petrie (Santa Clara, California);  David Stout (Palo Alto, California);  Paul E. Penwell (Sausalito, California);  Sigridur Suman (Hayward, California);  Allen Dodge (Newark, California)
ABSTRACT Systems and methods for producing microcrystalline alpha alane are provided herein. An exemplary process for producing microcrystalline alpha alane includes reacting lithium aluminum hydride and aluminum chloride in a solvent to produce alane etherate, filtering alane etherate from the reactant, combining the filtered alane etherate with a lithium borohydride solution to produce solids that include microcrystalline alane etherate, removing remaining solvent from the solids, creating a slurry from the solids and an aromatic solvent, and heating the slurry to convert the microcrystalline alane etherate to microcrystalline alpha alane.
FILED Wednesday, November 07, 2012
APPL NO 13/671090
ART UNIT 1768 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 6/06 (20130101) Original (OR) Class

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/065 (20130101)
H01M 10/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676630 Cornwell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Charles F. Cornwell (Vicksburg, Mississippi);  Charles P. Marsh (Urbana, Illinois);  Charles R. Welch (Vicksburg, Mississippi);  Benjamin Ulmen (Urbana, Illinois);  Dustin L. Majure (Madison, Mississippi)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S) Charles F. Cornwell (Vicksburg, Mississippi);  Charles P. Marsh (Urbana, Illinois);  Charles R. Welch (Vicksburg, Mississippi);  Benjamin Ulmen (Urbana, Illinois);  Dustin L. Majure (Madison, Mississippi)
ABSTRACT Carbon nanotubes have excellent mechanical properties such as low density, high stiffness, and exceptional strength making them ideal candidates for reinforcement material in a wide range of high-performance composites. Fibers with increased tensile strengths are produced by employing plasma treatment under various conditions. Tensile strength is improved by at least 35%, relative to an untreated fiber. Methods of making such high strength carbon nanotube fibers via plasma processing are disclosed.
FILED Tuesday, May 28, 2013
APPL NO 13/903979
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 31/0253 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676823 Reshetnyak et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Rhode Island Council on Postsecondary Education (statutory successor to Board of Governors for Higher Education, State of Rhode Island and Providence Plantations) (Warick, Rhode Island);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) Rhode Island Council on Postsecondary Education (statutory successor to Board of Governors for Higher Education, State of Rhode Island and Providence Plantations) (Warwick, Rhode Island);  Yale University (New Haven, Connecticut)
INVENTOR(S) Yana K. Reshetnyak (South Kingstown, Rhode Island);  Oleg A. Andreev (South Kingstown, Rhode Island);  Ursula Lehnert (Richmond, United Kingdom);  Donald M. Engelman (New Haven, Connecticut)
ABSTRACT A polypeptide with a predominantly hydrophobic sequence long enough to span a membrane lipid bilayer as a transmembrane helix (TM) and comprising one or more dissociable groups inserts across a membrane spontaneously in a pH-dependant fashion placing one terminus inside cell. The polypeptide conjugated with various functional moieties delivers and accumulates them at cell membrane with low extracellular pH. The functional moiety conjugated with polypeptide terminus placed inside cell are translocated through the cell membrane in cytosol. The peptide and its variants or non-peptide analogs can be used to deliver therapeutic, prophylactic, diagnostic, imaging, gene regulation, cell regulation, or immunologic agents to or inside of cells in vitro or in vivo in tissue at low extracellular pH.
FILED Tuesday, April 22, 2014
APPL NO 14/258964
ART UNIT 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 47/48246 (20130101)

Peptides
C07K 14/001 (20130101) Original (OR) Class
C07K 14/215 (20130101)
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676895 Harkal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
APPLICANT(S) Umesh D. Harkal (Fargo, North Dakota);  Andrew J. Muehlberg (Fargo, North Dakota);  Peter A. Edwards (Cokato, Minnesota);  Dean C. Webster (Fargo, North Dakota)
ASSIGNEE(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
INVENTOR(S) Umesh D. Harkal (Fargo, North Dakota);  Andrew J. Muehlberg (Fargo, North Dakota);  Peter A. Edwards (Cokato, Minnesota);  Dean C. Webster (Fargo, North Dakota)
ABSTRACT The invention relates to novel aqueous coating compositions containing epoxy urethane (glycidyl carbamate) functional resin. An aqueous coating composition comprises a polyfunctional oligomer having at least two epoxy urethane functional groups and a polyalkylene oxide chain, an optional surfactant, and water. The aqueous coating compositions of the invention can be dispersed in water with or without added surfactants to form a dispersion containing no volatile organic solvent. The invention provides a method for making aqueous coating compositions containing epoxy urethane functional resin as well. Water-dispersible epoxy urethane compounds of the aqueous coating compositions are also provided.
FILED Tuesday, July 20, 2010
APPL NO 12/840019
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/706 (20130101)
C08G 18/2805 (20130101)
C08G 18/2845 (20130101) Original (OR) Class
C08G 59/5026 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 163/00 (20130101)
C09D 163/06 (20130101)
C09D 175/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676916 Gupta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) Nikhil Gupta (Ossining, New York);  Vasanth Chakravarthy Shunmugasamy (Brooklyn, New York)
ABSTRACT A multifunctional syntactic foam including a matrix material and hollow particles, where a first and second material property of the syntactic foam are tailored on the basis of the wall thickness and volume fraction of the hollow particles.
FILED Monday, July 28, 2014
APPL NO 14/444677
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/32 (20130101) Original (OR) Class
C08J 2205/044 (20130101)
C08J 2331/02 (20130101)
C08J 2363/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/088 (20130101)
G01N 33/20 (20130101)
G01N 33/44 (20130101)
G01N 2203/0094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677075 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Colin Michael Calabrese (Evanston, Illinois);  William Morris (Evanston, Illinois)
ABSTRACT Disclosed herein are metal-ligand complexes containing polynucleotides, compounds for making the same, and methods of using the same.
FILED Wednesday, April 23, 2014
APPL NO 14/786569
ART UNIT 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7052 (20130101)
A61K 31/7088 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/581 (20130101)
C07F 15/02 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54346 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677601 Jacquemin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Joseph W. Jacquemin (Panama City Beach, Florida);  Pedro Bracho (Lynn Haven, Florida)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Joseph W. Jacquemin (Panama City Beach, Florida);  Pedro Bracho (Lynn Haven, Florida)
ABSTRACT A pivoting joint assembly includes a base, a plate, and at least one bolt. The base has one or more semi-spherical sockets with each socket having a centrally-positioned hole extending through the base. The plate has one or more semi-spherical sockets recessed within the plate with aligned semi-spherical protrusions extending from the plate. The plate has a hole extending through a central portion of each of the plate's sockets and a corresponding protrusion aligned therewith. Each protrusion is partially fitted in a corresponding socket in the base. Each bolt has a head and a post extending from the head. The head includes a semi-spherical portion adjacent to the post. The post extends through aligned holes in the plate and base. The post is coupled to the base such that the semi-spherical portion of bolt's head nests within one of the plate's sockets.
FILED Thursday, November 06, 2014
APPL NO 14/534981
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 11/06 (20130101)
F16C 11/106 (20130101)
F16C 11/0604 (20130101) Original (OR) Class
F16C 11/0685 (20130101)
F16C 11/0695 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 403/32032 (20150115)
Y10T 403/32311 (20150115)
Y10T 403/32573 (20150115)
Y10T 403/32639 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677662 Maners et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Brian Scott Maners (Cloverdale, Indiana);  David Russell Bockmiller (Keller, Texas)
ASSIGNEE(S) Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Brian Scott Maners (Cloverdale, Indiana);  David Russell Bockmiller (Keller, Texas)
ABSTRACT The present disclosure provides a lubricating system for a dual splined hollow shaft. A fluid dam is formed circumferentially within the hollow shaft to control the lubrication of the dual splines. The fluid dam includes a pair of sidewalls extending radially inward from the inner wall of the hollow shaft to a height defined by a top wall. A channel formed through the pair of sidewalls permits the movement of lubricant between splines of the hollow shaft. An egress port extends from the top wall of the dam through the outer wall of the hollow shaft to permit lubricant to exit the hollow shaft.
FILED Tuesday, December 16, 2008
APPL NO 12/316782
ART UNIT 3654 — Material and Article Handling
CURRENT CPC
Couplings for Transmitting Rotation; Clutches; Brakes
F16D 2001/103 (20130101)
F16D 2300/06 (20130101)

Gearing
F16H 57/043 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677741 Hsu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Chia Wei Hsu (Cambridge, Massachusetts);  Wenjun Qiu (Chicago, Illinois);  Bo Zhen (Cambridge, Massachusetts);  Ofer Shapira (Cambridge, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT Transparent displays enable many useful applications, including heads-up displays for cars and aircraft as well as displays on eyeglasses and glass windows. Unfortunately, transparent displays made of organic light-emitting diodes are typically expensive and opaque. Heads-up displays often require fixed light sources and have limited viewing angles. And transparent displays that use frequency conversion are typically energy inefficient. Conversely, the present transparent displays operate by scattering visible light from resonant nanoparticles with narrowband scattering cross sections and small absorption cross sections. More specifically, projecting an image onto a transparent screen doped with nanoparticles that selectively scatter light at the image wavelength(s) yields an image on the screen visible to an observer. Because the nanoparticles scatter light at only certain wavelengths, the screen is practically transparent under ambient light. Exemplary transparent scattering displays can be simple, inexpensive, scalable to large sizes, viewable over wide angular ranges, energy efficient, and transparent simultaneously.
FILED Monday, April 04, 2016
APPL NO 15/090348
ART UNIT 2875 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for
F21V 9/08 (20130101)
F21V 9/12 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 5/0242 (20130101)
G02B 5/0278 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/19 (20130101)
G02F 1/0126 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 21/62 (20130101)

Displaying; Advertising; Signs; Labels or Name-plates; Seals
G09F 13/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677817 Dudis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Douglas S. Dudis (Tipp City, Ohio);  Joel E. Schmidt (Pasadena, California);  Douglas J. Miller (Cedarville, Ohio)
ABSTRACT Ammonium carbamate-based methods and systems for management of thermal loads, particularly low-quality, high-flux thermal loads. The increase in temperature in heat sensitive devices is mitigated by the endothermic decomposition of ammonium carbamate into carbon dioxide and ammonia gases. This process has an energy density an order of magnitude greater than conventional thermal management materials and is particularly useful for temperatures between 20° C. and 100° C. Systems incorporating ammonium carbamate may be controlled by regulating the fluid flow, overhead pressure, temperature, or combinations thereof.
FILED Wednesday, February 27, 2013
APPL NO 13/778685
ART UNIT 3744 — Optics
CURRENT CPC
Kitchen Equipment; Coffee Mills; Spice Mills; Apparatus for Making Beverages
A47J 36/28 (20130101)

Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 81/3484 (20130101)

Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment
F25J 2205/24 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 5/02 (20130101)
F28D 15/00 (20130101) Original (OR) Class
F28D 20/02 (20130101)
F28D 20/003 (20130101)
F28D 20/0034 (20130101)
F28D 20/0056 (20130101)
F28D 2021/0022 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 23/00 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/142 (20130101)
Y02E 60/145 (20130101)
Y02E 60/147 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677863 Palathingal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Mohan J. Palathingal (Oradell, New Jersey);  Kip Hess (Sparta, New Jersey);  Gregory M. Kolasa (Wantage, New Jersey);  Sung Chung (Dover, New Jersey);  Marco Duca (Mt. Arlington, New Jersey)
ABSTRACT A kinetic energy penetrator for use in small caliber ammunition, which penetrator can utilize composite material small sabots. A large shear area in the sabot having a small number of decreasingly sized buttress grooves, mate to the penetrator shaft making use of composite material sabots feasible. Lightening of the penetrator through substitution of composite material sabots results in greater velocity with higher kinetic energy on lethal impact. The fewer grooves aerodynamically lessen drag and likewise tend to boost velocity plus lethal impact.
FILED Tuesday, January 26, 2016
APPL NO 15/006679
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 14/061 (20130101) Original (OR) Class
F42B 14/062 (20130101)
F42B 14/068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677949 Han
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) NUTECH VENTURES (Lincoln, Nebraska)
INVENTOR(S) Ming Han (Lincoln, Nebraska)
ABSTRACT An in-line fiber-optic temperature sensor is disclosed. In an implementation, the in-line fiber-optic temperature sensor includes an optically transmissive fiber, a reflector, a microstructured fiber defining a channel therein for receiving a fluid, and a Fabry-Perot cavity in fluid communication with the microstructured fiber. The microstructured fiber can be retained between the optically transmissive fiber and the reflector. The Fabry-Perot cavity defined by a material and configured to receive a gas having an index of refraction that changes in a known way with temperature and pressure changes in fluid communication with the channel of the microstructured fiber. The in-line fiber-optic temperature sensor also includes a chamber defined between the optically transmissive fiber and the microstructured fiber for connecting in fluid communication with a vacuum/pressure source for changing pressure. The in-line fiber-optic temperature sensor also includes a sensor for determining an optical interferometric reflection spectrum associated with the Fabry-Perot cavity.
FILED Tuesday, October 28, 2014
APPL NO 14/526168
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/45 (20130101)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 1/26 (20130101)
G01K 11/125 (20130101)
G01K 11/3206 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678004 Bartoli et al.
FUNDED BY
Department of Defense (DOD)
National Science Foundation (NSF)
APPLICANT(S) Lehigh University (Bethlehem, Pennsylvania)
ASSIGNEE(S) LEHIGH UNIVERSITY (, None)
INVENTOR(S) Filbert Bartoli (Center Valley, Pennsylvania);  Qiaoqiang Gan (East Amherst, New York);  Yongkang Gao (Bethlehem, Pennsylvania)
ABSTRACT An optical device includes a transparent substrate and a conductive layer disposed over an upper surface of the transparent substrate. The conductive layer defines at least one groove inwardly extending from an upper surface and includes an aperture that is spaced apart from the at least one groove. An interface between the upper surface of the conductive layer and an ambient medium defines an optical branch along which surface plasmon polariton modes are excited in response to at least partially coherent light being received by the optical device.
FILED Wednesday, March 09, 2016
APPL NO 15/064738
ART UNIT 2886 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/01 (20130101)
G01N 21/45 (20130101) Original (OR) Class
G01N 21/553 (20130101)
G01N 21/554 (20130101)
G01N 21/7703 (20130101)
G01N 2021/458 (20130101)
G01N 2021/5903 (20130101)
G01N 2021/7779 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/1226 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678013 Bratkovski et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Alexandre M. Bratkovski (Mountain View, California);  Zhiyong Li (Foster City, California);  Wei Wu (Palo Alto, California);  Min Hu (Sunnyvale, California);  R. Stanley Williams (Portola Valley, California);  Ansoon Kim (Mountain View, California)
ASSIGNEE(S) Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S) Alexandre M. Bratkovski (Mountain View, California);  Zhiyong Li (Foster City, California);  Wei Wu (Palo Alto, California);  Min Hu (Sunnyvale, California);  R. Stanley Williams (Portola Valley, California);  Ansoon Kim (Mountain View, California)
ABSTRACT Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a substrate and a sensing member formed on a surface of the substrate. The sensing member includes collapsible signal amplifying structures and an area surrounding the collapsible signal amplifying structures that enables self-positioning of droplets exposed thereto toward the collapsible signal amplifying structures.
FILED Friday, April 20, 2012
APPL NO 14/394295
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5088 (20130101)
B01L 2300/161 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0819 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/648 (20130101)
G01N 21/658 (20130101) Original (OR) Class
G01N 35/00009 (20130101)
G01N 2035/00019 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678032 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Universitat Autonoma de Barcelona (Bellaterra, Spain)
ASSIGNEE(S) The Regents Of The University Of California (Oakland, California);  Universitat Autonoma De Barcelona (Bellatera (Barcelona), Spain)
INVENTOR(S) Joseph Wang (San Diego, California);  Joshua Ray Windmiller (Del Mar, California);  Aoife O'Mahony (San Diego, California);  Xavier Cetó (La Figuerosa, Spain);  Manel Del Valle (Terrassa, Spain)
ABSTRACT Methods, systems, and devices are disclosed for the identification of chemical agents and determination of their level of exposure using electrochemical detection and advanced signal processing. In one aspect, a method includes collecting a sample from a surface containing a chemical agent to an electrode on a sensor such that the chemical agent transfers on the electrode, detecting an electrochemical signal of the chemical agent on the electrode to transduce chemical information associated with the chemical agent to an electrical signal, processing the electrical signal to obtain electrochemical spectral signature data to identify the chemical agent and generating a series of coefficients of the electrochemical spectral signature data to reduce the data, and classifying the chemical information based on the series of coefficients among preselected data sets to determine a level of exposure to the chemical agent.
FILED Tuesday, October 29, 2013
APPL NO 14/439641
ART UNIT 1759 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/48 (20130101)
G01N 27/307 (20130101) Original (OR) Class
G01N 33/0057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678038 Austin et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Robert H. Austin (Princeton, New Jersey);  Zhaoning Yu (Princeton, New Jersey);  Jonas O. Tegenfeldt (Lund, Sweden);  Stephen Y. Chou (Princeton, New Jersey);  Han Cao (San Diego, California)
ABSTRACT Nanochannel arrays that enable high-throughput macromolecular analysis are disclosed. Also disclosed are methods of preparing nanochannel arrays and nanofluidic chips. Methods of analyzing macromolecules, such as entire strands of genomic DNA, are also disclosed, as well as systems for carrying out these methods.
FILED Friday, November 15, 2013
APPL NO 14/081322
ART UNIT 1759 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/447 (20130101)
G01N 27/44791 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678062 Ildstad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
ASSIGNEE(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S) Suzanne T. Ildstad (Prospect, Kentucky);  Mary Jane Elliott (Brandenburg, Kentucky)
ABSTRACT Methods of expanding FCs or stem cells are provided herein, as are methods of screening for compounds that increase expression of DOCK2 or decrease expression of Arhgap18, either of which improves engraftment.
FILED Friday, September 21, 2012
APPL NO 14/346505
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0639 (20130101)
C12N 2501/998 (20130101)
C12N 2502/1171 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5029 (20130101)
G01N 33/5073 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678077 Rubin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Mark A. Rubin (New York, New York);  Juan Miguel Mosquera (New York, New York);  Kyung Park (Stamford, Connecticut);  Ya-Lin Chiu (Island Park, New York);  Francesca Demichelis (New York, New York)
ABSTRACT This invention relates to a triple immunostaining assay (ERG/TFF3/HMWCK) for sensitive and specific detection of prostate cancer. Positive staining for at least one of ERG or TFF3 combined with negative staining of HMWCK in a sample such as prostate tissue sample is indicative of cancer.
FILED Wednesday, May 15, 2013
APPL NO 14/401184
ART UNIT 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/18 (20130101)
C07K 16/26 (20130101)
C07K 16/32 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57434 (20130101) Original (OR) Class
G01N 2333/47 (20130101)
G01N 2333/4742 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678088 Whitesides et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Defense Science and Engineering Graduate Fellowship (NDSEG)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Children's Medical Center Corporation (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Children's Medical Center Corporation (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) George M. Whitesides (Newton, Massachusetts);  Ashok A. Kumar (Medford, Massachusetts);  Jonathan W. Hennek (Somerville, Massachusetts);  Caeul Lim (Boston, Massachusetts);  Yovany Moreno (Cambridge, Massachusetts);  Charles R. Mace (Auburn, New York);  Manoj T. Duraisingh (Cambridge, Massachusetts);  Matthew R. Patton (Cambridge, Massachusetts);  Si-yi Ryan Lee (Cambridge, Massachusetts);  Gaetana D'Alesio-Spina (Cambridge, Massachusetts);  Carlo Brugnara (Boston, Massachusetts);  Thomas P. Stossel (Boston, Massachusetts)
ABSTRACT An aqueous multi-phase system for diagnosis of sickle cell disease is described, including two or more phase-separated phases including: a first aqueous phase including a first phase component and having a first density between about 1.025 g/cm3 and about 1.095 g/cm3; and a second aqueous phase including a second phase component and having a second density between about 1.100 g/cm3 and about 1.140 g/cm3; wherein the first density is lower than the second density; and each of the first and second phase components include at least one polymer.
FILED Monday, April 28, 2014
APPL NO 14/785980
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/05 (20130101)
G01N 33/80 (20130101) Original (OR) Class
G01N 33/491 (20130101)
G01N 2015/003 (20130101)
G01N 2015/0073 (20130101)
G01N 2015/0076 (20130101)
G01N 2800/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678152 Maliuk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
National Security Agency (NSA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Dzmitry S. Maliuk (Addison, Texas);  Franco Stellari (Waldwick, New Jersey);  Alan J. Weger (Mohegan Lake, New York);  Peilin Song (Lagrangeville, New York)
ABSTRACT A scan chain latch circuit, a method of operating a latch circuit in a scan chain, and a computer-readable medium having stored thereon a data structure defining a scan chain latch circuit for instantiation on a semiconductor die are disclosed. In an embodiment, the scan chain latch circuit comprises a first latch for holding one data value, a second latch for holding another data value, and a multiplexor. The one data value is applied to a first data input of the multiplexor and the another data value is applied to a second data input of the multiplexor. An alternating clock signal is applied to a select input of the multiplexor to control the output of the multiplexor, wherein the output of the multiplexor toggles between the two data values held in the two latches at a defined frequency.
FILED Tuesday, April 26, 2016
APPL NO 15/138737
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/3177 (20130101)
G01R 31/31723 (20130101) Original (OR) Class
G01R 31/31727 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678186 Alexson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Dimitri Arthur Alexson (Fairfax, Virginia);  Doran Dakota Smith (Rockville, Maryland)
ABSTRACT A probe for use in Magnetic Resonance Force Microscopy (MRFM) to provide an image of a sample comprising: a magnetic field source adapted to orient the spin of the nuclei in a sample; a detector capable of detecting a magnetic field comprising an oscillator; at least one conductor substantially surrounding the oscillator for forming a RF antenna for transmitting a radio frequency electromagnetic field; whereby the at least one conductor transmits a radio frequency electromagnetic field that influences the nuclei in the sample, and whereby the detector detects how the nuclei are influenced through the oscillations of the oscillator to provide identification information concerning the content of the sample. Also included is a method for magnetic resonance force microscopy of a sample.
FILED Thursday, January 31, 2013
APPL NO 13/755115
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/08 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 60/52 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/46 (20130101) Original (OR) Class
G01R 33/323 (20130101)
G01R 33/34053 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678209 Ruff et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) William C Ruff (Catonsville, Maryland);  Barry Lee Stann (Edgewater, Maryland);  Mark M Giza (Kensington, Maryland);  William B. Lawler (Annapolis, Maryland)
ABSTRACT A system comprising a laser for transmitting a beam of light towards a target area; a controller for controlling the output of the laser; a receiver for collecting reflected pulses of light reflected from the target area, the receiver comprising a plurality of receive elements, each of the receive elements having a different field of view; a combiner for combining the outputs of the receive elements into one composite signal of the target area; an interface circuitry for converting the composite signal into an image; display unit displaying output from interface circuitry.
FILED Thursday, March 21, 2013
APPL NO 13/848312
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4816 (20130101)
G01S 7/4861 (20130101)
G01S 17/42 (20130101)
G01S 17/89 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 6/06 (20130101)
G02B 26/0833 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678215 Ramlall
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
INVENTOR(S) Rohan Y. Ramlall (Brentwood, California)
ABSTRACT A method for predicting a GPS pseudorange error includes receiving a first plurality of pseudorange errors at a plurality of different times for a plurality of global positioning system (GPS) satellites. The method also includes creating, using a processor, a first matrix. Each element of the first matrix is determined using a portion of the first plurality of pseudorange errors. The method yet further includes creating, using the processor, a second matrix that includes at least a portion of the first plurality of pseudorange errors. A size of the second matrix is determined by comparing each element of the first matrix to a predetermined threshold. The method still further includes predicting, using the processor, a second plurality of pseudorange errors for the plurality of GPS satellites using the first plurality of pseudorange errors and the second matrix.
FILED Tuesday, April 01, 2014
APPL NO 14/242168
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/005 (20130101)
G01C 21/165 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 19/23 (20130101)
G01S 19/40 (20130101) Original (OR) Class
G01S 19/47 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678271 Thacker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Oracle International Corporation (Redwood City, California)
ASSIGNEE(S) ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California)
INVENTOR(S) Hiren D. Thacker (San Diego, California);  Ashok V. Krishnamoorthy (San Diego, California);  Xuezhe Zheng (San Diego, California);  John E. Cunningham (San Diego, California)
ABSTRACT A chip package includes an optical integrated circuit (such as a hybrid integrated circuit) and an integrated circuit that are proximate to each other in the chip package. The integrated circuit includes electrical circuits that modulate data, communicate data, and serialize/deserialize data, and the optical integrated circuit communicates optical signals with very high bandwidth. Moreover, a front surface of the integrated circuit is electrically coupled to a top surface of an interposer, and a top surface of the integrated circuit is electrically coupled to a front surface of the optical integrated circuit. Furthermore, a bottom surface of the optical integrated circuit faces the top surface of the interposer, and the front surface of the optical integrated circuit is optically coupled to an optical-fiber receptacle, which in turn is optically coupled to an optical-fiber connector.
FILED Monday, January 26, 2015
APPL NO 14/605650
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/30 (20130101)
G02B 6/32 (20130101)
G02B 6/4219 (20130101)
G02B 6/4257 (20130101)
G02B 6/4274 (20130101)
G02B 6/12004 (20130101) Original (OR) Class
G02B 2006/12061 (20130101)
G02B 2006/12142 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/49827 (20130101)
H01L 23/49838 (20130101)
H01L 23/49894 (20130101)
H01L 25/167 (20130101)
H01L 2224/16225 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/15311 (20130101)

Transmission
H04B 10/803 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678276 Goldsmith et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Randall Howard Goldsmith (Madison, Wisconsin);  Kassandra Ann Knapper (Madison, Wisconsin);  Kevin Daniel Heylman (Madison, Wisconsin)
ABSTRACT Optical microresonator platforms are provided comprising a substrate having a surface, a plurality of SiO2 pillars, and a plurality of SiO2 whispering gallery mode (WGM) optical microresonators, each SiO2 pillar extending from the surface of the substrate and terminating in a corresponding SiO2 WGM optical microresonator of the plurality of SiO2 WGM optical microresonators, wherein the substrate, the plurality of SiO2 pillars and the plurality of SiO2 WGM optical microresonators form a monolithic structure, and further wherein the substrate is substantially transparent to visible light. The substrate may be a SiO2 substrate and the SiO2 WGM optical microresonator may be a SiO2 optical microtoroid.
FILED Thursday, January 07, 2016
APPL NO 14/990296
ART UNIT 2883 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/7746 (20130101)
G01N 2201/08 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/13 (20130101)
G02B 6/12004 (20130101)
G02B 6/29341 (20130101) Original (OR) Class
G02B 2006/12038 (20130101)
G02B 2006/12169 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678289 Schultz et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Mark D. Schultz (Ossining, New York);  Shurong Tian (Mount Kisco, New York)
ABSTRACT An optical coupling system includes a substrate, an electronic die comprising a plurality of coupling holes for passing light, an optical element die attached to a bottom surface of the electronic die, the electronic die attached to the substrate such that the electronic die covers a cavity in the substrate and the optical element die resides within the cavity of the substrate. The system may also include a thermally conductive lid that covers and contacts the electronic die and the substrate and has a coupling aperture that enables light that passes through the coupling holes to pass through the thermally conductive lid. The system may also include an optical cable coupler comprising a coupling section that laterally fits within the coupling aperture and a body section disposed above the coupling section that is laterally larger than the coupling section. A method for providing the above system is also disclosed herein.
FILED Wednesday, December 02, 2015
APPL NO 14/956484
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/4242 (20130101)
G02B 6/4244 (20130101)
G02B 6/4245 (20130101)
G02B 6/4267 (20130101)
G02B 6/4269 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679091 Choi
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kwong-Kit Choi (Brookeville, Virginia)
ABSTRACT A method for designing a photodetector comprising an array of pixels: selecting at a material composition for the photodetector; determining a configuration of at least one pixel in the array of pixels using a computer simulation, each pixel comprising an active region and a diffractive region, and a photodetector/air interface through which light enters, the computer simulation operating to process different configurations of the pixel to determine an optimal configuration for a predetermined wavelength or wavelength range occurring when waves reflected by the diffractive element form a constructive interference pattern inside the active region to thereby increase the quantum efficiency of the photodetector. An infrared photodetector produced by the method.
FILED Friday, January 18, 2013
APPL NO 13/745338
ART UNIT 2896 — AI & Simulation/Modeling
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Electric Digital Data Processing
G06F 17/5045 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1446 (20130101)
H01L 27/14601 (20130101)
H01L 27/14603 (20130101)
H01L 27/14683 (20130101)
H01L 31/09 (20130101)
H01L 31/0232 (20130101)
H01L 31/035236 (20130101)
H01L 31/035281 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679216 Pinkus et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Alan R Pinkus (Bellbrook, Ohio);  David W Dommett (Beavercreek, Ohio);  Harry Lee Task (Tuscon, Arizona)
ABSTRACT A system and method are provided for assessing a resolution of an optical sensor. An image is obtained from the optical sensor. A target area is selected from the image. The selected area is subjected to a thresholding process to generate a binary image. Pixels at a center of the binary image are tagged. The remaining pixels of the binary image are looped through, where pixels that are not already tagged, are touching a tagged pixel, and are of the same color of previously tagged pixels are tagged. A plurality of distances associated with each corner of the binary image is calculated from the corner to the nearest tagged pixel in a row or column of pixels. At least two shortest distances of the calculated plurality of distances are selected to determine an orientation of an object defined by the tagged pixels in the generated binary image.
FILED Thursday, May 05, 2016
APPL NO 15/147122
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/38 (20130101)
G06K 9/40 (20130101)
G06K 9/52 (20130101)
G06K 9/209 (20130101)
G06K 9/2081 (20130101)
G06K 9/3208 (20130101) Original (OR) Class
G06K 9/3241 (20130101)
G06K 9/4604 (20130101)
G06K 9/4652 (20130101)
G06K 9/6201 (20130101)
G06K 2009/4666 (20130101)

Image Data Processing or Generation, in General
G06T 7/60 (20130101)
G06T 2207/20021 (20130101)

Pictorial Communication, e.g Television
H04N 17/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679241 Nugent et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) KnowmTech, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) KnowmTech, LLC (Santa Fe, New Mexico)
INVENTOR(S) Alex Nugent (Santa Fe, New Mexico);  Timothy Molter (Oberstdorf, Germany)
ABSTRACT A thermodynamic random access memory includes one or more AHaH (Anti-Hebbian and Hebbian) node wherein read out of data is accomplished via a common summing electrode through memristive components and wherein multiple input cells are simultaneously active. A ktRAM architecture comprising a memory wherein each input synapse or “bit” of the memory interacts on or with a common electrode through a common “dendritic” electrode, and wherein each input can be individually driven. Each input constitutes a memory cell driving a common electrode.
FILED Friday, August 15, 2014
APPL NO 14/460668
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/063 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679247 Koutra et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Danai Koutra (Pittsburgh, Pennsylvania);  David M. Lubensky (Brookfield, Connecticut);  Hanghang Tong (Ossining, New York)
ABSTRACT A method of building a soft linkage between a plurality of graphs includes initializing a correspondence between type-1 and type-2 objects in the plurality of graphs, and reducing a cost function by alternately updating the type-1 correspondence and updating the type-2 correspondence.
FILED Thursday, September 19, 2013
APPL NO 14/032105
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/022 (20130101) Original (OR) Class
G06N 5/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679261 Hoover et al.
FUNDED BY
Department of Defense (DOD)
Defense Logistics Agency (DLA)
APPLICANT(S) ACCENTURE GLOBAL SOLUTIONS LIMITED (Dublin, Ireland)
ASSIGNEE(S) ACCENTURE GLOBAL SOLUTIONS LIMITED (Dublin, Ireland)
INVENTOR(S) James Hoover (Mechanicsburg, Pennsylvania);  Jeffrey Scott Miller (Fairfax Station, Virginia);  Lisa Wester (Alexandria, Virginia);  Randall C. Gowat (Arlington, Virginia)
ABSTRACT A machine learning classifier based procurement system determines a price risk score, a supplier risk score, and an item risk score for bids based on classifications performed by a machine learning classifier. The scores are compared to respective thresholds to determine if any of the bids are associated with a high-risk procurement.
FILED Wednesday, February 22, 2017
APPL NO 15/439183
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/30294 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 99/005 (20130101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/067 (20130101)
G06Q 10/0635 (20130101)
G06Q 30/0611 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679360 Fleischer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Office of Sponsored Research (OSR)
APPLICANT(S) Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) Trustees Of Princeton University (Princeton, New Jersey)
INVENTOR(S) Jason W. Fleischer (Princeton, New Jersey);  Chien-Hung Lu (Princeton, New Jersey);  Stefan Muenzel (Princeton, New Jersey)
ABSTRACT A relatively high-resolution image from a conventional camera can be computationally combined with a relatively low-resolution wavefront measurement from, for example, a Shack-Hartmann sensor in order to construct a relatively high-resolution light-field image.
FILED Friday, May 09, 2014
APPL NO 14/274600
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 9/00 (20130101)
G01J 2009/002 (20130101)

Image Data Processing or Generation, in General
G06T 3/4061 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679409 Black et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Brown University (Providence, Rhode Island)
ASSIGNEE(S) Brown University (Providence, Rhode Island)
INVENTOR(S) Michael J. Black (Tuebingen, Germany);  Peng Guan (Mountain View, California)
ABSTRACT Systems, methods, and computer-readable storage media for simulating realistic clothing. The system generates a clothing deformation model for a clothing type, wherein the clothing deformation model factors a change of clothing shape due to rigid limb rotation, pose-independent body shape, and pose-dependent deformations. Next, the system generates a custom-shaped garment for a given body by mapping, via the clothing deformation model, body shape parameters to clothing shape parameters. The system then automatically dresses the given body with the custom-shaped garment.
FILED Friday, February 15, 2013
APPL NO 14/372140
ART UNIT 2614 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 17/5009 (20130101)
G06F 2217/32 (20130101)

Image Data Processing or Generation, in General
G06T 17/00 (20130101) Original (OR) Class
G06T 19/20 (20130101)
G06T 2210/16 (20130101)
G06T 2219/2016 (20130101)
G06T 2219/2021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679645 Elmegreen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Bruce G. Elmegreen (Goldens Bridge, New York);  Glenn J. Martyna (Croton on Hudson, New York);  Dennis M. Newns (Yorktown Heights, New York);  Alejandro G. Schrott (New York, New York)
ABSTRACT A nonvolatile memory storage device includes a ferroelectric (FE) material coupled with a piezoresistive (PR) material through an inherent piezoelectric response of the FE material, wherein an electrical resistance of the PR material is dependent on a compressive stress applied thereto, the compressive stress caused by a remanent strain of the FE material resulting from a polarization of the FE material, such that a polarized state of the FE material results in a first resistance value of the PR material, and a depolarized state of the FE material results in a second resistance value of the PR material.
FILED Tuesday, December 22, 2015
APPL NO 14/977752
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/22 (20130101)
G11C 11/221 (20130101)
G11C 11/2275 (20130101)
G11C 13/00 (20130101)
G11C 13/0002 (20130101)
G11C 13/0004 (20130101)
G11C 13/0069 (20130101) Original (OR) Class
G11C 2013/0095 (20130101)
G11C 2213/79 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679654 Rumberg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S) WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia)
INVENTOR(S) Brandon David Rumberg (Morgantown, West Virginia);  David W. Graham (Morgantown, West Virginia)
ABSTRACT Aspects of a continuous-time memory cell circuit are described. In various embodiments, the memory cell circuit may comprise a memory cell, a current source coupled to the memory cell, and circuitry for programming the memory cell at an adaptive rate, based on a target voltage for programming, using a feedback loop between a gate terminal of the memory cell and a reference control input. Based on the circuitry for programming, the memory cell may be programmed according to various voltage and/or current references, by linear injection and/or tunneling mechanisms. According to various aspects, the circuitry for programming drives a memory cell to converge to a voltage target for programming within a short period of time and to a suitable level of accuracy.
FILED Friday, November 13, 2015
APPL NO 14/940683
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 16/06 (20130101)
G11C 16/10 (20130101) Original (OR) Class
G11C 16/26 (20130101)
G11C 16/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679766 Hite et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jennifer K. Hite (Arlington, Virginia);  Francis J. Kub (Arnold, Maryland);  Charles R. Eddy, Jr. (Columbia, Maryland);  Nelson Garces (Alexandria, Virginia)
ABSTRACT Disclosed herein is a method of: depositing a patterned mask layer on an N-polar GaN epitaxial layer of a sapphire, silicon, or silicon carbide substrate; depositing an AlN inversion layer on the open areas; removing any remaining mask; and depositing a III-N epitaxial layer to simultaneously produce N-polar material and III-polar material. Also disclosed herein is: depositing an AlN inversion layer on an N-polar bulk III-N substrate and depositing a III-N epitaxial layer to produce III-polar material. Also disclosed herein is: depositing an inversion layer on a III-polar bulk III-N substrate and depositing a III-N epitaxial layer to produce N-polar material. Also disclosed herein is a composition having: a bulk III-N substrate; an inversion layer on portions of the substrate; and a III-N epitaxial layer on the inversion layer. The III-N epitaxial layer is of the opposite polarity of the surface of the substrate.
FILED Friday, May 20, 2016
APPL NO 15/159976
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0237 (20130101)
H01L 21/0242 (20130101)
H01L 21/0254 (20130101) Original (OR) Class
H01L 21/0262 (20130101)
H01L 21/02378 (20130101)
H01L 21/02381 (20130101)
H01L 21/02389 (20130101)
H01L 21/02439 (20130101)
H01L 21/02458 (20130101)
H01L 21/02494 (20130101)
H01L 21/02502 (20130101)
H01L 21/02639 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679779 Taylor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) David P. Taylor (Hawthorne, California);  Margaret H. Abraham (Portola Valley, California)
ABSTRACT Embodiments of the present invention provide systems and methods for depositing materials on either side of a freestanding film using selectively thermally-assisted chemical vapor deposition (STA-CVD), and structures formed using same. A freestanding film, which is suspended over a cavity defined in a substrate, is exposed to a fluidic CVD precursor that reacts to form a solid material when exposed to heat. The freestanding film is then selectively heated in the presence of the precursor. The CVD precursor preferentially deposits on the surface(s) of the freestanding film.
FILED Tuesday, March 12, 2013
APPL NO 13/797549
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 2203/0109 (20130101)

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00373 (20130101)
B81C 2201/0176 (20130101)
B81C 2201/0188 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/01 (20130101)
C23C 16/04 (20130101)
C23C 16/18 (20130101)
C23C 16/46 (20130101)
C23C 16/481 (20130101)
C23C 16/483 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/024 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/285 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/3065 (20130101)
H01L 21/28506 (20130101) Original (OR) Class
H01L 27/13 (20130101)
H01L 28/40 (20130101)
H01L 28/87 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680061 Jain et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Sensor Electronic Technology, Inc. (Columbia, South Carolina)
ASSIGNEE(S) Sensor Electronic Technology, Inc. (Columbia, South Carolina)
INVENTOR(S) Rakesh Jain (Columbia, South Carolina);  Maxim S. Shatalov (Columbia, South Carolina);  Alexander Dobrinsky (Loudonville, New York);  Michael Shur (Latham, New York)
ABSTRACT A device having a layer with a patterned surface for improving the growth of semiconductor layers, such as group III nitride-based semiconductor layers with a high concentration of aluminum, is provided. The patterned surface can include a substantially flat top surface and a plurality of stress reducing regions, such as openings. The substantially flat top surface can have a root mean square roughness less than approximately 0.5 nanometers, and the stress reducing regions can have a characteristic size between approximately 0.1 microns and approximately five microns and a depth of at least 0.2 microns. A layer of group-III nitride material can be grown on the first layer and have a thickness at least twice the characteristic size of the stress reducing regions.
FILED Monday, July 18, 2016
APPL NO 15/212659
ART UNIT 2823 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0242 (20130101)
H01L 21/0243 (20130101)
H01L 21/0254 (20130101)
H01L 21/0265 (20130101)
H01L 21/02458 (20130101)
H01L 21/02639 (20130101)
H01L 21/02658 (20130101)
H01L 29/34 (20130101)
H01L 29/205 (20130101)
H01L 29/778 (20130101)
H01L 29/2003 (20130101)
H01L 29/7787 (20130101)
H01L 29/66462 (20130101)
H01L 33/06 (20130101)
H01L 33/007 (20130101)
H01L 33/10 (20130101)
H01L 33/12 (20130101)
H01L 33/22 (20130101) Original (OR) Class
H01L 33/24 (20130101)
H01L 33/32 (20130101)
H01L 2933/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680158 Huang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Yu Huang (Los Angeles, California);  Yujing Li (Los Angeles, California)
ABSTRACT A fuel cell includes: (1) an anode; (2) a cathode; and (3) an electrolyte disposed between the anode and the cathode. At least one of the anode and the cathode includes an electro-catalyst dispersed on a hybrid support, the hybrid support includes a first, carbon-based support and a second support different from the first, carbon-based support, and a weight percentage of the second support is at least 10% relative to a combined weight of the first, carbon-based support and the second support.
FILED Monday, April 29, 2013
APPL NO 14/397628
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/921 (20130101)
H01M 4/926 (20130101)
H01M 4/8605 (20130101)
H01M 4/9083 (20130101) Original (OR) Class
H01M 2008/1095 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680385 Pietrantonio et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) GE Aviation Systems LLC (Grand Rapids, Michigan)
ASSIGNEE(S) GE AVIATION SYSTEMS LLC (Grand Rapids, Michigan)
INVENTOR(S) Michael Pietrantonio (Winter Springs, Florida);  Michael Carl Ludwig (Margate, Florida);  Mohamed Aly Elsayed (Pompano Beach, Florida)
ABSTRACT A power converter includes a circuit board having an elongated anode receiving an input voltage and an input current and an elongated cathode providing an output voltage and an output current, and a plurality of diodes electrically arranged in parallel between the anode and cathode. The parallel diodes convert the input voltage to an output voltage, convert the input current to an output current.
FILED Tuesday, November 04, 2014
APPL NO 14/532928
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/14 (20130101)
H02M 3/3378 (20130101)
H02M 3/33546 (20130101) Original (OR) Class
H02M 2001/0058 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/1432 (20130101)
H05K 7/20927 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 70/1491 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680472 Trivedi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) INTEL CORPORATION (Santa Clara, California)
ASSIGNEE(S) INTEL CORPORATION (Santa Clara, California)
INVENTOR(S) Amit R. Trivedi (Atlanta, Georgia);  Jaydeep P. Kulkarni (Portland, Oregon);  Carlos Tokunaga (Hillsboro, Oregon);  Muhammad M. Khellah (Tigard, Oregon);  James W. Tschanz (Portland, Oregon)
ABSTRACT Embodiments include apparatuses, methods, and systems for voltage level shifting a data signal between a low voltage domain and a high voltage domain. In embodiments, a voltage level shifter circuit may include adaptive keeper circuitry, enhanced interruptible supply circuitry, and/or capacitive boosting circuitry to reduce a minimum voltage of the low voltage domain that is supported by the voltage level shifter circuit. Other embodiments may be described and claimed.
FILED Tuesday, June 14, 2016
APPL NO 15/182486
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 19/018521 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680561 Cannon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Corey Cannon (Bloomington, Indiana);  Andrew Martin (Ellettsville, Indiana);  Brian Brackee (Bloomington, Indiana)
ABSTRACT An efficient and reliable way to send various information including position location information (PLI) and emergency messages (EM) using or within a mobile satellite system (MSS) using different message formats including short message (e.g., short burst data (SBD), etc.), between mobile users as provided. Embodiments also use global positioning systems (GPS) used in some cases with the PLI system. Various embodiments improve communications efficiency and reliability of message transmission through various types of MSS. Embodiments include a method or approach to interface SBD PLI messages from mobile end user terminals (EUT) to common operating picture (COP) application programs as provided. Exemplary methods interface and translate MSS short messages (e.g., SBD) to extensible markup language (XML) message format and communicate converted messages to COP application program within a computer using a TCP/IP interface.
FILED Thursday, February 04, 2016
APPL NO 15/015354
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission
H04B 7/18513 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 4/22 (20130101)
H04W 4/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680928 Medard et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) NATIONAL SCIENCE FOUNDATION (Arlington, Virginia)
INVENTOR(S) Muriel Medard (Cambridge, Massachusetts);  Supratim Deb (Cambridge, Massachusetts);  Ralf Koetter (Champaign, Illinois)
ABSTRACT A method and computer program product for providing a random linear coding approach to distributed data storage is presented. A file is broken into a plurality of pieces. For every peer (peer means storage-location with limited storage space), the number of coded-pieces the peer can store is determined. Each of the coded-piece is determined by taking random linear combination of all the pieces of the entire file. The associate code-vector is stored for every coded-piece. The file is retrieved by collecting code-vectors and the coded-pieces from the peers and viewing the collected code-vectors as a matrix. When a dimension of the matrix is equal to the number of pieces of the file, the file is recovered using the collection of code vectors in the matrix.
FILED Wednesday, July 01, 2015
APPL NO 14/788968
ART UNIT 2441 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 17/30209 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/104 (20130101)
H04L 67/1095 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09681250 Luo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S) University of Maryland (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Yuancheng Luo (College Park, Maryland);  Ramani Duraiswami (Highland, Maryland);  Dmitry N. Zotkin (Greenbelt, Maryland)
ABSTRACT A system for generating and outputting three-dimensional audio data using head-related transfer functions (HRTFs) includes a processor configured to perform operations comprising: using a collection of previously measured HRTFs for audio signals corresponding to multiple directions for at least one subject; performing non-parametric Gaussian process hyper-parameter training on the collection of previously measured HRTFs to generate one or more predicted HRTFs that are different from the previously measured HRTFs; and generating and outputting three-dimensional audio data based on at least the one or more predicted HRTFs.
FILED Tuesday, May 27, 2014
APPL NO 14/120522
ART UNIT 2656 — Digital Audio Data Processing
CURRENT CPC
Stereophonic Systems
H04S 5/00 (20130101)
H04S 7/303 (20130101) Original (OR) Class
H04S 7/304 (20130101)
H04S 2400/15 (20130101)
H04S 2420/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09681529 Kuo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Spencer Kuo (River Edge, New Jersey);  Skip Williams (Dayton, Ohio);  Daniel Bivolaru (Hampton, Virginia);  Campbell Carter (Dayton, Ohio)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Spencer Kuo (River Edge, New Jersey);  Skip Williams (Dayton, Ohio);  Daniel Bivolaru (Hampton, Virginia);  Campbell Carter (Dayton, Ohio)
ABSTRACT A plasma torch module combining arc and microwave discharges is disclosed. One embodiment serves to enhance the size and enthalpy of the plasma torch and has a very large operational range of the airflow rate, from subsonic to supersonic flow speed. Increase of airflow in the torch operation can increase not only the size of the torch plasma and the cycle energy of the arc discharge but also the lifetime of the torch module and the torch can operate stably with very low airflow.
FILED Monday, January 08, 2007
APPL NO 11/621034
ART UNIT 3742 — Digital Communications
CURRENT CPC
Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/46 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09681592 Tuan et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) The Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S) Christopher Tuan (Omaha, Nebraska);  Lim Nguyen (Bellevue, Nebraska)
ABSTRACT Conductive concrete mixtures are described that are configured to provide EMP shielding and reflect and/or absorb, for instance, EM waves propagating through the conductive concrete mixture. The conductive concrete mixtures include cement, water, conductive carbon material, magnetic material, and metallic conductive material. The conductive carbon material may include conductive carbon particles, conductive carbon powder, and/or coke breeze. The metallic conductive material may include steel fibers, and the magnetic material may include taconite. The conductive concrete mixture may also include supplementary cementitious materials (SCM). A method of making a concrete structure includes pouring a concrete mixture to form conductive concrete, and positioning a first conductive screen within the conductive concrete proximate to an exterior surface of the conductive concrete. The method also includes positioning a second conductive screen within the conductive concrete in electrical contact with the first conductive screen.
FILED Tuesday, June 24, 2014
APPL NO 14/392258
ART UNIT 3638 — Static Structures, Supports and Furniture
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/022 (20130101)
C04B 14/024 (20130101)
C04B 14/48 (20130101)
C04B 14/305 (20130101)
C04B 14/308 (20130101)
C04B 18/146 (20130101)
C04B 28/04 (20130101)
C04B 28/04 (20130101)
C04B 2103/32 (20130101)
C04B 2111/94 (20130101)
C04B 2111/00258 (20130101)

General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings
E04B 1/92 (20130101)
E04B 2001/925 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/16 (20130101)
H01B 1/18 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 9/0003 (20130101) Original (OR) Class

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/94 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 09675561 Bencherif et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Sidi A. Bencherif (Dorchester, Massachusetts);  Roger Warren Sands (Chicago, Illinois);  Sandeep T. Koshy (Boston, Massachusetts);  David J. Mooney (Sudbury, Massachusetts)
ABSTRACT The invention provides polymer compositions for cell and drug delivery.
FILED Tuesday, January 28, 2014
APPL NO 14/166689
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101)
A61K 9/7007 (20130101) Original (OR) Class
A61K 39/0011 (20130101)
A61K 39/39 (20130101)
A61K 47/36 (20130101)
A61K 47/42 (20130101)
A61K 2039/5152 (20130101)
A61K 2039/55522 (20130101)
A61K 2039/55561 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/50 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 2300/252 (20130101)
A61L 2300/258 (20130101)
A61L 2400/06 (20130101)

Compositions of Macromolecular Compounds
C08L 5/04 (20130101)
C08L 89/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675717 Kim et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The University of Toledo (Toledo, Ohio)
ASSIGNEE(S) The University of Toledo (Toldeo, Ohio)
INVENTOR(S) Dong-Shik Kim (Sylvania, Ohio);  Youngwoo Seo (Toledo, Ohio)
ABSTRACT The antifouling coating is a composite material consisting of fluorinated electroactive bipolymers and magnetic particles. This composite material is coated on a solid surface to make a smooth durable grassy coating. The coating generates electrical current when an electrolytic liquid flows over it, which prevents bacterial cells from attaching to the surface. It prevents virus and protein attachment. It also prevents chemical corrosion of a surface. The composite material itself, and the antifouling method that uses fluoride compounds and electrical current that is generated by the fluid flow are disclosed for a patent. The composite material can be applied to medical devices, biomedical devices, industrial equipment, ship's hulls, food processing equipment, food processors, drinking water distribution systems, and home electrical appliances.
FILED Friday, May 30, 2014
APPL NO 14/291795
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/03 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 2003/2265 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/16 (20130101)
C09D 5/23 (20130101)
C09D 5/24 (20130101)
C09D 5/1687 (20130101)
C09D 7/1216 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09675902 Lipkens et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) FloDesign Sonics, Inc. (Wilbraham, Massachusetts)
ASSIGNEE(S) FLODESIGN SONICS, INC. (Wilbraham, Massachusetts)
INVENTOR(S) Bart Lipkens (Hampden, Massachusetts);  Jason Dionne (Simsbury, Massachusetts);  Ari Mercado (Agawam, Massachusetts);  Brian Dutra (Rockland, Massachusetts);  Walter M. Presz, Jr. (Wilbraham, Massachusetts);  Thomas J. Kennedy, III (Wilbraham, Massachusetts);  Louis Masi (Longmeadow, Massachusetts)
ABSTRACT An acoustic standing wave is utilized to separate components from a multi-component fluid, such as oil from an oil-water mixture, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allows for trapping of the oil as the oil coalesces, agglomerates, and becomes more buoyant than the water.
FILED Tuesday, January 19, 2016
APPL NO 15/000573
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 17/04 (20130101) Original (OR) Class
B01D 43/00 (20130101)

Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/0644 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 47/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676621 Chen et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Junhong Chen (Kenosha, Wisconsin);  Shun Mao (Milwaukee, Wisconsin);  Ganhua Lu (Milwaukee, Wisconsin)
ASSIGNEE(S) UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Junhong Chen (Kenosha, Wisconsin);  Shun Mao (Milwaukee, Wisconsin);  Ganhua Lu (Milwaukee, Wisconsin)
ABSTRACT The disclosure provides a field-effect transistor (FET)-based biosensor and uses thereof. In particular, to FET-based biosensors using thermally reduced graphene-based sheets as a conducting channel decorated with nanoparticle-biomolecule conjugates. The present disclosure also relates to FET-based biosensors using metal nitride/graphene hybrid sheets. The disclosure provides a method for detecting a target biomolecule in a sample using the FET-based biosensor described herein.
FILED Friday, February 17, 2012
APPL NO 13/399288
ART UNIT 1677 — Material and Article Handling
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4145 (20130101)
G01N 27/4146 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676676 Hartung, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) John Hartung, Jr. (Evanston, Illinois);  Brendan L. Quigley (Pasadena, California);  Peter K. Dornan (Pasadena, California);  Robert H. Grubbs (South Pasadena, California)
ABSTRACT This invention relates generally to C—H activated ruthenium olefin metathesis catalyst compounds which are stereogenic at the ruthenium center, to their preparation, and the use of such catalysts in the metathesis of olefins and olefin compounds. In particular, the invention relates to the use of C—H activated ruthenium olefin metathesis catalyst compounds in Z-selective olefin metathesis reactions, enantio-selective olefin metathesis reactions, and enantio-Z-selective olefin metathesis reactions. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and industrial and fine chemicals chemistry.
FILED Wednesday, July 01, 2015
APPL NO 14/789848
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/2208 (20130101)
B01J 31/2278 (20130101)
B01J 2231/54 (20130101)
B01J 2231/543 (20130101)
B01J 2531/821 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 37/02 (20130101) Original (OR) Class
C07B 2200/09 (20130101)

Acyclic or Carbocyclic Compounds
C07C 6/04 (20130101)
C07C 6/04 (20130101)
C07C 15/50 (20130101)
C07C 29/32 (20130101)
C07C 29/32 (20130101)
C07C 33/025 (20130101)
C07C 67/293 (20130101)
C07C 67/293 (20130101)
C07C 67/293 (20130101)
C07C 67/293 (20130101)
C07C 67/343 (20130101)
C07C 67/343 (20130101)
C07C 67/475 (20130101)
C07C 67/475 (20130101)
C07C 69/63 (20130101)
C07C 69/78 (20130101)
C07C 69/145 (20130101)
C07C 69/593 (20130101)
C07C 69/608 (20130101)
C07C 2101/08 (20130101)
C07C 2101/14 (20130101)
C07C 2102/08 (20130101)
C07C 2531/22 (20130101)

Heterocyclic Compounds
C07D 207/46 (20130101)
C07D 211/94 (20130101)
C07D 317/12 (20130101)
C07D 471/04 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/1892 (20130101)
C07F 15/0046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676679 Alabugin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S) Igor V. Alabugin (Tallahassee, Florida);  Kamalkishore Pati (Tallahassee, Florida)
ABSTRACT The present disclosure is directed to a traceless directing group in a radical cascade. The chemo- and regioselectivity of the initial attack in skipped oligoalkynes is controlled by a propargyl alkoxy moiety. Radical translocations lead to the boomerang return of radical center to the site of initial attack where it assists to the elimination of the directing functionality via β-scission in the last step of the cascade. In some aspects, the reaction of the present invention is catalyzed by a stannane moiety, which allows further via facile reactions with electrophiles as well as Stille and Suzuki cross-coupling reactions. This selective radical transformation opens a new approach for the controlled transformation of skipped oligoalkynes into polycyclic ribbons of tunable dimensions.
FILED Tuesday, November 03, 2015
APPL NO 14/930860
ART UNIT 1671 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 1/325 (20130101) Original (OR) Class
C07C 1/325 (20130101)
C07C 1/325 (20130101)
C07C 13/62 (20130101)
C07C 13/66 (20130101)
C07C 17/26 (20130101)
C07C 17/26 (20130101)
C07C 17/26 (20130101)
C07C 22/08 (20130101)
C07C 25/22 (20130101)
C07C 41/18 (20130101)
C07C 41/18 (20130101)
C07C 43/21 (20130101)
C07C 45/67 (20130101)
C07C 45/67 (20130101)
C07C 49/84 (20130101)
C07C 253/30 (20130101)
C07C 253/30 (20130101)
C07C 253/30 (20130101)
C07C 255/52 (20130101)
C07C 255/54 (20130101)
C07C 2103/40 (20130101)
C07C 2103/54 (20130101)

Heterocyclic Compounds
C07D 221/18 (20130101)
C07D 317/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676708 Toscano et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) John P. Toscano (Glen Arm, Maryland);  Art D. Sutton (Mount Pleasant, Wisconsin)
ABSTRACT Protected HNO donors designed to undergo non-enzymatic release at neutral pH via an intramolecular cyclization-elimination are disclosed. The rate of cyclization, and therefore HNO release, can be controlled by substituents and chain length. Thus, biologically useful HNO donors having tunable HNO release rates are provided.
FILED Wednesday, October 30, 2013
APPL NO 14/439800
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/27 (20130101)
A61K 31/265 (20130101)
A61K 31/4152 (20130101)
A61K 45/06 (20130101)

Acyclic or Carbocyclic Compounds
C07C 311/48 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676743 Coates et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Geoffrey W. Coates (Lansing, New York);  John W. Kramer (Ithaca, New York)
ABSTRACT Catalysts and methods for the carbonylation of epoxides to substituted 3-hydroxy-δ-lactones and β-lactones are disclosed.
FILED Wednesday, September 04, 2013
APPL NO 14/017803
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 309/30 (20130101) Original (OR) Class
C07D 311/96 (20130101)
C07D 405/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676823 Reshetnyak et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Rhode Island Council on Postsecondary Education (statutory successor to Board of Governors for Higher Education, State of Rhode Island and Providence Plantations) (Warick, Rhode Island);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) Rhode Island Council on Postsecondary Education (statutory successor to Board of Governors for Higher Education, State of Rhode Island and Providence Plantations) (Warwick, Rhode Island);  Yale University (New Haven, Connecticut)
INVENTOR(S) Yana K. Reshetnyak (South Kingstown, Rhode Island);  Oleg A. Andreev (South Kingstown, Rhode Island);  Ursula Lehnert (Richmond, United Kingdom);  Donald M. Engelman (New Haven, Connecticut)
ABSTRACT A polypeptide with a predominantly hydrophobic sequence long enough to span a membrane lipid bilayer as a transmembrane helix (TM) and comprising one or more dissociable groups inserts across a membrane spontaneously in a pH-dependant fashion placing one terminus inside cell. The polypeptide conjugated with various functional moieties delivers and accumulates them at cell membrane with low extracellular pH. The functional moiety conjugated with polypeptide terminus placed inside cell are translocated through the cell membrane in cytosol. The peptide and its variants or non-peptide analogs can be used to deliver therapeutic, prophylactic, diagnostic, imaging, gene regulation, cell regulation, or immunologic agents to or inside of cells in vitro or in vivo in tissue at low extracellular pH.
FILED Tuesday, April 22, 2014
APPL NO 14/258964
ART UNIT 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 47/48246 (20130101)

Peptides
C07K 14/001 (20130101) Original (OR) Class
C07K 14/215 (20130101)
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677064 Edd et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
U.S. Public Health Service (USPHS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Jon F Edd (Arlington, Massachusetts);  Memhet Toner (Charlestown, Massachusetts);  Dino DiCarlo (Los Angeles, California);  Daniel Irimia (Charlestown, Massachusetts)
ABSTRACT Microfluidic devices and methods for the encapsulation of particles within liquid droplets are disclosed. The new methods and devices form 1-100 picoliter-size monodisperse droplets containing the particles, such as single cells, encapsulated in individual liquid droplets. The particles can be encapsulated in droplets of a fluid by passing a fluid containing the particles through a high aspect-ratio microchannel to order the particles in the fluid, followed by forming the fluid into droplets. The resulting fraction of the liquid droplets with a single particle (e.g., a cell) is higher than the corresponding fraction of single-particle liquid droplets predicted by Poisson statistics.
FILED Monday, June 29, 2015
APPL NO 14/754420
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 11/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677274 Saiidi
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Board of Regents of the Nevada System of Higher Education on behalf of the University of Nevada, Reno (Reno, Nevada)
ASSIGNEE(S) Board of Regents of the Nevada System of Higher Education on behalf of the University of Nevada, Reno (Reno, Nevada)
INVENTOR(S) Mehdi Saiidi (Reno, Nevada)
ABSTRACT Disclosed herein are support column structures which can be used to support bridges, buildings or other structures. In some cases, a support column structure can be deconstructable and include one or more removable elements. In some cases, a support column structure can include shape memory alloy reinforcing bars. In some cases, a removable element of a support column structure can include an engineered cementitious composite. In some cases, a removable element includes one or more sleeves to separate an engineered cementitious composite from one or more shape memory alloy reinforcing bars. Methods include assembling and disassembling a support column structure.
FILED Thursday, October 01, 2015
APPL NO 14/873052
ART UNIT 3633 — Static Structures, Supports and Furniture
CURRENT CPC
Construction of Bridges, or Viaducts; Assembly of Bridges
E01D 19/02 (20130101)

Foundations; Excavations; Embankments; Underground or Underwater Structures
E02D 27/01 (20130101)
E02D 27/42 (20130101)
E02D 2300/00 (20130101)

Structural Elements; Building Materials
E04C 3/34 (20130101) Original (OR) Class
E04C 3/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677741 Hsu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Chia Wei Hsu (Cambridge, Massachusetts);  Wenjun Qiu (Chicago, Illinois);  Bo Zhen (Cambridge, Massachusetts);  Ofer Shapira (Cambridge, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT Transparent displays enable many useful applications, including heads-up displays for cars and aircraft as well as displays on eyeglasses and glass windows. Unfortunately, transparent displays made of organic light-emitting diodes are typically expensive and opaque. Heads-up displays often require fixed light sources and have limited viewing angles. And transparent displays that use frequency conversion are typically energy inefficient. Conversely, the present transparent displays operate by scattering visible light from resonant nanoparticles with narrowband scattering cross sections and small absorption cross sections. More specifically, projecting an image onto a transparent screen doped with nanoparticles that selectively scatter light at the image wavelength(s) yields an image on the screen visible to an observer. Because the nanoparticles scatter light at only certain wavelengths, the screen is practically transparent under ambient light. Exemplary transparent scattering displays can be simple, inexpensive, scalable to large sizes, viewable over wide angular ranges, energy efficient, and transparent simultaneously.
FILED Monday, April 04, 2016
APPL NO 15/090348
ART UNIT 2875 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for
F21V 9/08 (20130101)
F21V 9/12 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 5/0242 (20130101)
G02B 5/0278 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/19 (20130101)
G02F 1/0126 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 21/62 (20130101)

Displaying; Advertising; Signs; Labels or Name-plates; Seals
G09F 13/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677999 Dasgupta
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purnendu K Dasgupta (Arlington, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Purnendu K Dasgupta (Arlington, Texas)
ABSTRACT A system for increasing light throughput in cavity enhanced spectrometry, and a model for cavity enhanced absorption measurements are presented. The cavity has an entrance mirror, an opposed exit mirror and a detector positioned adjacent the exit mirror. An input aperture is defined in the entrance mirror to allow light from a source to enter the cavity. The input aperture improves light throughput without significant departure from the theoretically predicted amplification of absorbance. This results in improvement of detection limits, even with mirrors of modest reflectivity and inexpensive detectors.
FILED Thursday, March 26, 2015
APPL NO 14/670269
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/031 (20130101)
G01N 21/31 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678004 Bartoli et al.
FUNDED BY
Department of Defense (DOD)
National Science Foundation (NSF)
APPLICANT(S) Lehigh University (Bethlehem, Pennsylvania)
ASSIGNEE(S) LEHIGH UNIVERSITY (, None)
INVENTOR(S) Filbert Bartoli (Center Valley, Pennsylvania);  Qiaoqiang Gan (East Amherst, New York);  Yongkang Gao (Bethlehem, Pennsylvania)
ABSTRACT An optical device includes a transparent substrate and a conductive layer disposed over an upper surface of the transparent substrate. The conductive layer defines at least one groove inwardly extending from an upper surface and includes an aperture that is spaced apart from the at least one groove. An interface between the upper surface of the conductive layer and an ambient medium defines an optical branch along which surface plasmon polariton modes are excited in response to at least partially coherent light being received by the optical device.
FILED Wednesday, March 09, 2016
APPL NO 15/064738
ART UNIT 2886 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/01 (20130101)
G01N 21/45 (20130101) Original (OR) Class
G01N 21/553 (20130101)
G01N 21/554 (20130101)
G01N 21/7703 (20130101)
G01N 2021/458 (20130101)
G01N 2021/5903 (20130101)
G01N 2021/7779 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/1226 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678007 Backman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Vadim Backman (Chicago, Illinois);  Ji Yi (Evanston, Illinois)
ABSTRACT A method and system to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT) is disclosed. Tissue is modeled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. By measuring optical quantities of tissue (including the scattering power of the OCT spectrum, the reflection albedo α defined as the ratio of scattering coefficient μs, and the backscattering coefficient μb), the RI correlation function can be inversely deduced and the full set of optical scattering properties can be obtained.
FILED Friday, October 12, 2012
APPL NO 13/651196
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/4795 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678037 Liang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents Of The University Of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Xiaogan Liang (Ann Arbor, Michigan);  Katsuo Kurabayashi (Ann Arbor, Michigan)
ABSTRACT Atomically layered transition metal dichalcogenides (TMDCs) exhibit a significant potential to enable low-cost transistor biosensors that permit single-molecule-level quantification of biomolecules. Two different principles for operating such biosensors are presented. In one arrangement, antibody receptors are functionalized on an insulating layer deposited onto the channel of the transistor. The charge introduced through antigen-antibody binding is capacitively coupled with the channel and shifts the threshold voltage without significantly changing the transconductance. In another arrangement, antibodies are functionalized directly on the channel of the transistor. Antigen-antibody binding events mainly modulate the ON-state transconductance, which is attributed to the disordered potential formed in channel material.
FILED Thursday, October 08, 2015
APPL NO 14/878616
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4146 (20130101) Original (OR) Class
G01N 33/6863 (20130101)
G01N 2333/525 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/7781 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678276 Goldsmith et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Randall Howard Goldsmith (Madison, Wisconsin);  Kassandra Ann Knapper (Madison, Wisconsin);  Kevin Daniel Heylman (Madison, Wisconsin)
ABSTRACT Optical microresonator platforms are provided comprising a substrate having a surface, a plurality of SiO2 pillars, and a plurality of SiO2 whispering gallery mode (WGM) optical microresonators, each SiO2 pillar extending from the surface of the substrate and terminating in a corresponding SiO2 WGM optical microresonator of the plurality of SiO2 WGM optical microresonators, wherein the substrate, the plurality of SiO2 pillars and the plurality of SiO2 WGM optical microresonators form a monolithic structure, and further wherein the substrate is substantially transparent to visible light. The substrate may be a SiO2 substrate and the SiO2 WGM optical microresonator may be a SiO2 optical microtoroid.
FILED Thursday, January 07, 2016
APPL NO 14/990296
ART UNIT 2883 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/7746 (20130101)
G01N 2201/08 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/13 (20130101)
G02B 6/12004 (20130101)
G02B 6/29341 (20130101) Original (OR) Class
G02B 2006/12038 (20130101)
G02B 2006/12169 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678323 Orth et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Antony Orth (Somerville, Massachusetts);  Kenneth B. Crozier (West Melbourne, Australia)
ABSTRACT A microscope includes a multi-wavelength emitting laser light source. A microscope objective is configured to receive and expand input light emitted from the light source, and a dichroic mirror is configured to reflect the expanded input light. A micro lens array with a plurality of micro lenses splits the reflected and expanded input light onto a fluorescence producing sample. A lens collectively captures the fluorescence for each micro lens in the plurality of micro lenses, and a camera receives the fluorescence from the lens and produces an image of the sample based on the received fluorescence.
FILED Wednesday, June 10, 2015
APPL NO 14/735534
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/16 (20130101) Original (OR) Class
G02B 21/361 (20130101)
G02B 21/365 (20130101)

Image Data Processing or Generation, in General
G06T 5/50 (20130101)
G06T 2207/10024 (20130101)
G06T 2207/10052 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/10064 (20130101)
G06T 2207/20208 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678497 Karypis et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) George Karypis (Bloomington, Minnesota);  Dominique Welle LaSalle (St. Paul, Minnesota)
ABSTRACT Multiple parallel slave processes and a master process are assigned to a node executing an operating system such that the operating system maintains a ready queue comprising a list of one or more processes that are ready to be executed by at least one processing core. A parallel slave process takes an action that causes the operating system to keep the parallel slave process out of the ready queue. Based on receiving an indication that the parallel slave process is to be kept out of the ready queue, the master process sets the parallel slave process to a blocking state, selects a second parallel slave process that is in a runnable state but is currently kept from being in the ready queue, and takes an action that causes the operating system to add the parallel slave process that is in the runnable state to the ready queue.
FILED Thursday, August 28, 2014
APPL NO 14/471707
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/0421 (20130101) Original (OR) Class
G05B 2219/2231 (20130101)

Electric Digital Data Processing
G06F 9/4843 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679093 Kulathumani et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S) WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia)
INVENTOR(S) Vinod Kulathumani (Morgantown, West Virginia);  David W. Graham (Morgantown, West Virginia);  Brandon David Rumberg (Morgantown, West Virginia)
ABSTRACT According to some embodiments, a sensor network may be provided with re-programmable and/or reconfigurable analog circuitry configured to monitor data collected by the sensor network. The re-programmable and/or reconfigurable analog circuitry may also generate a wakeup signal in response to a defined wakeup event detected by the sensor network.
FILED Friday, February 20, 2015
APPL NO 14/627011
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Electric Digital Data Processing
G06F 1/32 (20130101)
G06F 1/3203 (20130101)
G06F 1/3206 (20130101)
G06F 15/7867 (20130101)
G06F 17/5054 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 4/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679360 Fleischer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Office of Sponsored Research (OSR)
APPLICANT(S) Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) Trustees Of Princeton University (Princeton, New Jersey)
INVENTOR(S) Jason W. Fleischer (Princeton, New Jersey);  Chien-Hung Lu (Princeton, New Jersey);  Stefan Muenzel (Princeton, New Jersey)
ABSTRACT A relatively high-resolution image from a conventional camera can be computationally combined with a relatively low-resolution wavefront measurement from, for example, a Shack-Hartmann sensor in order to construct a relatively high-resolution light-field image.
FILED Friday, May 09, 2014
APPL NO 14/274600
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 9/00 (20130101)
G01J 2009/002 (20130101)

Image Data Processing or Generation, in General
G06T 3/4061 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679671 Yoon
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Florida Research Foundation (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA REASEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Yong-Kyu Yoon (Gainesville, Florida)
ABSTRACT Various examples are provided for low ohmic loss radial superlattice conductors. In one example, among others, a conductor includes a plurality of radially distributed layers that include a non-permalloy core, a permalloy layer disposed on and encircling the non-permalloy core, and a non-permalloy layer disposed on and encircling the permalloy layer. The non-permalloy core and non-permalloy layer can include the same or different materials such as, e.g., aluminum, copper, silver, and gold. In some implementations, the non-permalloy core includes a void containing air or a non-conductive material such as, e.g., a polymer. The permalloy layer can include materials such as, e.g., NiFe, FeCo, NiFeCo, or NiFeMo. In another example, a via connector includes the plurality of radially distributed layers including the permalloy layer and the non-permalloy layer disposed on and encircling the permalloy layer. The via connector can extend through glass, silicon, organic, or other types of substrates.
FILED Friday, July 11, 2014
APPL NO 14/904457
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/02 (20130101) Original (OR) Class
H01B 7/30 (20130101)
H01B 11/18 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/66 (20130101)
H01L 23/49827 (20130101)
H01L 23/49866 (20130101)
H01L 23/49894 (20130101)
H01L 2223/6622 (20130101)
H01L 2223/6627 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680117 Bartoli et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Lehigh University (Bethlehem, Pennsylvania)
ASSIGNEE(S) LEHIGH UNIVERSITY (, None)
INVENTOR(S) Filbert Joseph Bartoli (Center Valley, Pennsylvania);  Beibei Zeng (Bethlehem, Pennsylvania)
ABSTRACT A thin film organic photovoltaic device or solar cell in one embodiment includes an organic active bilayer and an ultrathin two-dimensional metallic nanogrid as a transparent conducting electrode which receives incident light. The nanogrid excites surface plasmonic resonances at an interface between the nanogrid and active bilayer from the incident light to enhance photon absorption in the active bilayer below the nanogrid. In another embodiment, spatially separated nanograting electrodes may alternatively be formed by double one-dimensional nanogratings disposed on opposite sides of the organic active bilayer. The spatially separated nanogratings may be oriented perpendicular to each other.
FILED Thursday, April 03, 2014
APPL NO 14/781778
ART UNIT 1754 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/054 (20141201)
H01L 51/0037 (20130101)
H01L 51/0053 (20130101)
H01L 51/0091 (20130101)
H01L 51/424 (20130101)
H01L 51/442 (20130101)
H01L 51/445 (20130101)
H01L 51/447 (20130101) Original (OR) Class
H01L 2251/301 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680161 Yang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Hong Yang (Champaign, Illinois);  Jianbo Wu (Savoy, Illinois)
ABSTRACT A noble metal-based electrocatalyst comprises a bimetallic particle comprising a noble metal and a non-noble metal and having a polyhedral shape. The bimetallic particle comprises a surface-segregated composition where an atomic ratio of the noble metal to the non-noble metal is higher in a surface region and in a core region than in a sub-surface region between the surface and core regions. A method of treating a noble metal-based electrocatalyst comprises annealing a bimetallic particle comprising a noble metal and a non-noble metal and having a polyhedral shape at a temperature in the range of from about 100° C. to about 1100° C.
FILED Tuesday, July 15, 2014
APPL NO 14/331697
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/921 (20130101)
H01M 4/926 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680520 Gollakota et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) University of Washington through its Center For Commercialization (Seattle, Washington)
ASSIGNEE(S) University of Washington Through Its Center For Commercialization (Seattle, Washington)
INVENTOR(S) Shyamnath Gollakota (Seattle, Washington);  Joshua R. Smith (Seattle, Washington);  Vincent Liu (Seattle, Washington);  Aaron N. Parks (Seattle, Washington);  Vamsi Talla (Seattle, Washington)
ABSTRACT Apparatuses, systems, ambient backscatter transceivers, and methods for modulating a backscatter of an ambient RF signal are described. An example system may include an ambient backscatter transceiver comprising an antenna that is configured to receive a backscattered ambient radio frequency (RF) signal. The ambient backscatter transceiver is configured to demodulate the backscattered ambient RF signal to retrieve first data. The backscattered ambient RF signal is generated by backscattering an ambient RF signal at a first frequency. The ambient RF signal is encoded with modulated to provide second data at a second frequency.
FILED Thursday, July 09, 2015
APPL NO 14/795719
ART UNIT 2634 — Digital Communications
CURRENT CPC
Transmission
H04B 1/40 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680693 Barford et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Paul R. Barford (Madison, Wisconsin);  Jeffery Thomas Kline (Madison, Wisconsin);  Sangnam Nam (Madison, Wisconsin);  David John Plonka (Madison, Wisconsin);  Amos Ron (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Paul R. Barford (Madison, Wisconsin);  Jeffery Thomas Kline (Madison, Wisconsin);  Sangnam Nam (Madison, Wisconsin);  David John Plonka (Madison, Wisconsin);  Amos Ron (Madison, Wisconsin)
ABSTRACT A network anomaly detector evaluates two complementary measurements of network statistics, a time variation and correlation among those statistics, to provide an extremely robust detection of network anomalies. In one embodiment, the variability and correspondence are compared against historically derived thresholds to provide for a system that accommodates to local network conditions and evolving network qualities.
FILED Thursday, November 29, 2007
APPL NO 12/516766
ART UNIT 2468 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/064 (20130101) Original (OR) Class
H04L 41/142 (20130101)
H04L 43/16 (20130101)
H04L 43/045 (20130101)
H04L 63/1425 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680928 Medard et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) NATIONAL SCIENCE FOUNDATION (Arlington, Virginia)
INVENTOR(S) Muriel Medard (Cambridge, Massachusetts);  Supratim Deb (Cambridge, Massachusetts);  Ralf Koetter (Champaign, Illinois)
ABSTRACT A method and computer program product for providing a random linear coding approach to distributed data storage is presented. A file is broken into a plurality of pieces. For every peer (peer means storage-location with limited storage space), the number of coded-pieces the peer can store is determined. Each of the coded-piece is determined by taking random linear combination of all the pieces of the entire file. The associate code-vector is stored for every coded-piece. The file is retrieved by collecting code-vectors and the coded-pieces from the peers and viewing the collected code-vectors as a matrix. When a dimension of the matrix is equal to the number of pieces of the file, the file is recovered using the collection of code vectors in the matrix.
FILED Wednesday, July 01, 2015
APPL NO 14/788968
ART UNIT 2441 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 17/30209 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/104 (20130101)
H04L 67/1095 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09681250 Luo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S) University of Maryland (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Yuancheng Luo (College Park, Maryland);  Ramani Duraiswami (Highland, Maryland);  Dmitry N. Zotkin (Greenbelt, Maryland)
ABSTRACT A system for generating and outputting three-dimensional audio data using head-related transfer functions (HRTFs) includes a processor configured to perform operations comprising: using a collection of previously measured HRTFs for audio signals corresponding to multiple directions for at least one subject; performing non-parametric Gaussian process hyper-parameter training on the collection of previously measured HRTFs to generate one or more predicted HRTFs that are different from the previously measured HRTFs; and generating and outputting three-dimensional audio data based on at least the one or more predicted HRTFs.
FILED Tuesday, May 27, 2014
APPL NO 14/120522
ART UNIT 2656 — Digital Audio Data Processing
CURRENT CPC
Stereophonic Systems
H04S 5/00 (20130101)
H04S 7/303 (20130101) Original (OR) Class
H04S 7/304 (20130101)
H04S 2400/15 (20130101)
H04S 2420/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09681307 Taher et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Tanim Taher (Austin, Texas);  Dennis Roberson (Chicago, Illinois)
ASSIGNEE(S) Illinois Institute of Technology (Chicago, Illinois)
INVENTOR(S) Tanim Taher (Austin, Texas);  Dennis Roberson (Chicago, Illinois)
ABSTRACT A method and apparatus for determining and sharing RF spectrum availability. The method includes automatically sensing and analyzing a spectrum to identify used and/or unused portions of the spectrum, and automatically communicating the used and/or unused portions of the spectrum to a spectrum owner or a spectrum user. The invention has particular use in automatically identifying and quantifying current spectrum users, automatically reporting the current spectrum users to a spectrum owner, and/or allocating unused spectrum portions to users.
FILED Tuesday, September 22, 2015
APPL NO 14/861321
ART UNIT 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Wireless Communication Networks
H04W 16/14 (20130101) Original (OR) Class
H04W 72/10 (20130101)
H04W 72/085 (20130101)
H04W 72/0453 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09681389 Wentzloff et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) David D. Wentzloff (Ann Arbor, Michigan);  Jonathan K. Brown (Brookline, Massachusetts);  Kuo-Ken Huang (Ann Arbor, Michigan);  Elnaz Ansari (Ann Arbor, Michigan);  Ryan R. Rogel (Austin, Texas)
ABSTRACT An integrated ultra wideband transceiver. The transceiver comprises a transmitter, a receiver, and at least one on-chip monopole antenna electrically connected to at least one of the transmitter or receiver for transmitting and/or receiving electrical signals. The transceiver further comprises a clock generator comprising a temperature-compensated relaxation oscillator, a baseband controller electrically connected to, and configured to exert a measure of control over, at least one the transmitter, receiver, or clock generator, and a micro-battery operative to provide operating power to each of the transmitter, receiver, clock generator, and baseband controller.
FILED Monday, February 17, 2014
APPL NO 14/768143
ART UNIT 2633 — Digital Communications
CURRENT CPC
Pulse Technique
H03K 3/0231 (20130101)
H03K 5/24 (20130101)

Transmission
H04B 1/40 (20130101)
H04B 1/7183 (20130101)
H04B 1/71635 (20130101)
H04B 1/71637 (20130101)

Wireless Communication Networks
H04W 52/029 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 09676054 Bonnen et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Ford Global Technologies, LLC (Dearborn, Michigan)
ASSIGNEE(S) FORD GLOBAL TECHNOLOGIES, LLC (Dearborn, Michigan)
INVENTOR(S) John Joseph Francis Bonnen (Milford, Michigan);  Sergey Fedorovich Golovashchenko (Beverly Hills, Michigan);  Alexander Mamutov (Dearborn, Michigan);  Lloyd Douglas Maison (Brownstown Township, Michigan);  Scott Alwyn Dawson (Royal Oak, Michigan);  James deVries (Redford, Michigan)
ABSTRACT A cartridge assembly for a tool includes a cartridge body or casing that contains a conductor. A conductor is connected to a pulse generator or source of stored charge that is discharged to vaporize the conductor and create an electro-hydraulic or electro-magnetic shockwave that is used to impact or pulse weld two parts together.
FILED Friday, August 08, 2014
APPL NO 14/454968
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 20/06 (20130101) Original (OR) Class
B23K 20/2275 (20130101)
B23K 20/2336 (20130101)
B23K 2201/06 (20130101)
B23K 2203/10 (20130101)
B23K 2203/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676621 Chen et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Junhong Chen (Kenosha, Wisconsin);  Shun Mao (Milwaukee, Wisconsin);  Ganhua Lu (Milwaukee, Wisconsin)
ASSIGNEE(S) UWM Research Foundation, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Junhong Chen (Kenosha, Wisconsin);  Shun Mao (Milwaukee, Wisconsin);  Ganhua Lu (Milwaukee, Wisconsin)
ABSTRACT The disclosure provides a field-effect transistor (FET)-based biosensor and uses thereof. In particular, to FET-based biosensors using thermally reduced graphene-based sheets as a conducting channel decorated with nanoparticle-biomolecule conjugates. The present disclosure also relates to FET-based biosensors using metal nitride/graphene hybrid sheets. The disclosure provides a method for detecting a target biomolecule in a sample using the FET-based biosensor described herein.
FILED Friday, February 17, 2012
APPL NO 13/399288
ART UNIT 1677 — Material and Article Handling
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4145 (20130101)
G01N 27/4146 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676743 Coates et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Geoffrey W. Coates (Lansing, New York);  John W. Kramer (Ithaca, New York)
ABSTRACT Catalysts and methods for the carbonylation of epoxides to substituted 3-hydroxy-δ-lactones and β-lactones are disclosed.
FILED Wednesday, September 04, 2013
APPL NO 14/017803
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 309/30 (20130101) Original (OR) Class
C07D 311/96 (20130101)
C07D 405/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676807 Zaworotko et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Michael Zaworotko (Tampa, Florida);  Mona H. Mohamed (Tampa, Florida);  Sameh Elsaidi (Tampa, Florida)
ABSTRACT Embodiments of the present disclosure provide for multi-component metal-organic materials (MOMs), systems including the MOM, systems for separating components in a gas, methods of separating polarizable gases from a gas mixture, and the like.
FILED Thursday, October 31, 2013
APPL NO 14/437986
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/204 (20130101)
B01D 2257/504 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 1/08 (20130101)
C07F 3/06 (20130101)
C07F 11/005 (20130101)
C07F 15/045 (20130101)
C07F 15/065 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676830 Wogulis et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Mark Wogulis (Davis, California);  Matthew Sweeney (Sacramento, California);  Tia Heu (Elk Grove, California)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Mark Wogulis (Davis, California);  Matthew Sweeney (Sacramento, California);  Tia Heu (Elk Grove, California)
ABSTRACT The present invention relates to chimeric GH61 polypeptides having cellulolytic enhancing activity. The present invention also relates to polynucleotides encoding the chimeric GH61 polypeptides; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the chimeric GH61 polypeptides.
FILED Friday, November 18, 2011
APPL NO 13/883923
ART UNIT 1662 — Plants
CURRENT CPC
Peptides
C07K 14/38 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677054 Thompson et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) David N Thompson (Idaho Falls, Idaho);  William A Apel (Jackson, Wyoming);  Vicki S Thompson (Idaho Falls, Idaho);  David W Reed (Idaho Falls, Idaho);  Jeffrey A Lacey (Idaho Falls, Idaho)
ABSTRACT Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for glycosylating and/or post-translationally modifying proteins using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
FILED Monday, December 21, 2015
APPL NO 14/977349
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1048 (20130101)
C12N 9/1051 (20130101) Original (OR) Class
C12N 9/1288 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/00 (20130101)
C12P 21/005 (20130101)

Enzymes
C12Y 204/00 (20130101)
C12Y 204/01083 (20130101)
C12Y 207/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677193 Kellerman et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Varian Semiconductor Equipment Associates, Inc. (Gloucester, Massachusetts)
ASSIGNEE(S) Varian Semiconductor Equipment Associates, Inc. (Gloucester, Massachusetts)
INVENTOR(S) Peter L. Kellerman (Essex, Massachusetts);  Gregory D. Thronson (Groveland, Massachusetts);  Dawei Sun (Nashua, New Hampshire)
ABSTRACT In one embodiment, a sheet production apparatus comprises a vessel configured to hold a melt of a material. A cooling plate is disposed proximate the melt and is configured to form a sheet of the material on the melt. A first gas jet is configured to direct a gas toward an edge of the vessel. A sheet of a material is translated horizontally on a surface of the melt and the sheet is removed from the melt. The first gas jet may be directed at the meniscus and may stabilize this meniscus or increase local pressure within the meniscus.
FILED Tuesday, April 01, 2014
APPL NO 14/242566
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 9/00 (20130101)
C30B 11/00 (20130101)
C30B 15/00 (20130101)
C30B 15/002 (20130101)
C30B 15/06 (20130101)
C30B 15/22 (20130101)
C30B 15/24 (20130101)
C30B 15/34 (20130101)
C30B 28/10 (20130101)
C30B 29/06 (20130101)
C30B 29/52 (20130101)
C30B 29/64 (20130101)
C30B 35/00 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 117/1048 (20150115)
Y10T 117/1092 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677439 Gupta et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Cummins Inc. (Columbus, Indiana)
ASSIGNEE(S) Cummins Inc. (Columbus, Indiana)
INVENTOR(S) Aniket Gupta (Wuhan, China PRC);  Michael J. Cunningham (Greenwood, Indiana);  Michael J. Ruth (Franklin, Indiana);  Krishna P. Chilumukuru (Columbus, Indiana)
ABSTRACT Systems and methods are provided for managing low temperature NOx and HC emissions, such as during a cold start of an internal combustion engine. The systems and methods include storing NOx and HC emissions at low temperatures and passively releasing and treating these emissions as the temperature of the exhaust system increases.
FILED Tuesday, January 20, 2015
APPL NO 14/600262
ART UNIT 3748 — Static Structures, Supports and Furniture
CURRENT CPC
Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines
F01N 3/035 (20130101) Original (OR) Class
F01N 3/103 (20130101)
F01N 3/106 (20130101)
F01N 3/108 (20130101)
F01N 3/208 (20130101)
F01N 3/0807 (20130101)
F01N 3/0835 (20130101)
F01N 3/0842 (20130101)
F01N 9/00 (20130101)
F01N 9/002 (20130101)
F01N 13/009 (20140603)
F01N 13/0093 (20140603)
F01N 13/0097 (20140603)
F01N 2340/02 (20130101)
F01N 2570/12 (20130101)
F01N 2570/14 (20130101)
F01N 2610/02 (20130101)
F01N 2610/06 (20130101)
F01N 2610/146 (20130101)
F01N 2610/1406 (20130101)
F01N 2610/1453 (20130101)
F01N 2900/1402 (20130101)
F01N 2900/1404 (20130101)
F01N 2900/1602 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/24 (20130101)
Y02T 10/47 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677713 Aceves et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  Universidad de Guanajuato (Salamanca, Mexico)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  Universidad de Guanajuto (Guanajuato, Mexico)
INVENTOR(S) Salvador M. Aceves (Livermore, California);  Elias Rigoberto Ledesma-Orozco (Salamanca Gto., Mexico);  Francisco Espinosa-Loza (Livermore, California);  Guillaume Petitpas (Livermore, California);  Vernon A. Switzer (Livermore, California)
ABSTRACT A pressure vessel apparatus for cryogenic capable storage of hydrogen or other cryogenic gases at high pressure includes an insert with a parallel inlet duct, a perpendicular inlet duct connected to the parallel inlet. The perpendicular inlet duct and the parallel inlet duct connect the interior cavity with the external components. The insert also includes a parallel outlet duct and a perpendicular outlet duct connected to the parallel outlet duct. The perpendicular outlet duct and the parallel outlet duct connect the interior cavity with the external components.
FILED Tuesday, November 24, 2015
APPL NO 14/950527
ART UNIT 3728 — Fluid Handling and Dispensing
CURRENT CPC
Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 51/1644 (20130101)

Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 1/12 (20130101)
F17C 13/001 (20130101) Original (OR) Class
F17C 2201/0104 (20130101)
F17C 2203/03 (20130101)
F17C 2203/0629 (20130101)
F17C 2203/0643 (20130101)
F17C 2203/0646 (20130101)
F17C 2205/0352 (20130101)
F17C 2221/012 (20130101)
F17C 2270/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677741 Hsu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Chia Wei Hsu (Cambridge, Massachusetts);  Wenjun Qiu (Chicago, Illinois);  Bo Zhen (Cambridge, Massachusetts);  Ofer Shapira (Cambridge, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT Transparent displays enable many useful applications, including heads-up displays for cars and aircraft as well as displays on eyeglasses and glass windows. Unfortunately, transparent displays made of organic light-emitting diodes are typically expensive and opaque. Heads-up displays often require fixed light sources and have limited viewing angles. And transparent displays that use frequency conversion are typically energy inefficient. Conversely, the present transparent displays operate by scattering visible light from resonant nanoparticles with narrowband scattering cross sections and small absorption cross sections. More specifically, projecting an image onto a transparent screen doped with nanoparticles that selectively scatter light at the image wavelength(s) yields an image on the screen visible to an observer. Because the nanoparticles scatter light at only certain wavelengths, the screen is practically transparent under ambient light. Exemplary transparent scattering displays can be simple, inexpensive, scalable to large sizes, viewable over wide angular ranges, energy efficient, and transparent simultaneously.
FILED Monday, April 04, 2016
APPL NO 15/090348
ART UNIT 2875 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for
F21V 9/08 (20130101)
F21V 9/12 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 5/0242 (20130101)
G02B 5/0278 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/19 (20130101)
G02F 1/0126 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 21/62 (20130101)

Displaying; Advertising; Signs; Labels or Name-plates; Seals
G09F 13/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677792 Auringer et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Astronautics Corporation of America (Milwaukee, Wisconsin)
ASSIGNEE(S) ASTRONAUTICS CORPORATION OF AMERICA (Milwaukee, Wisconsin)
INVENTOR(S) Jon Jay Auringer (Poynette, Wisconsin);  Andre Michael Boeder (Monona, Wisconsin);  Jeremy Jonathan Chell (Madison, Wisconsin);  John Paul Leonard (Cambridge, Wisconsin);  Carl Bruno Zimm (Madison, Wisconsin)
ABSTRACT An active magnetic regenerative (AMR) refrigerator apparatus can include at least one AMR bed with a first end and a second end and a first heat exchanger (HEX) with a first end and a second end. The AMR refrigerator can also include a first pipe that fluidly connects the first end of the first HEX to the first end of the AMR bed and a second pipe that fluidly connects the second end of the first HEX to the first end of the AMR bed. The first pipe can divide into two or more sub-passages at the AMR bed. The second pipe can divide into two or more sub-passages at the AMR bed. The sub-passages of the first pipe and the second pipe can interleave at the AMR bed.
FILED Friday, December 12, 2014
APPL NO 14/569450
ART UNIT 3744 — Optics
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 21/00 (20130101) Original (OR) Class
F25B 2321/002 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 30/66 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677916 Hegyi et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California)
INVENTOR(S) Alex Hegyi (San Francisco, California);  Peter Kiesel (Palo Alto, California);  Ajay Raghavan (Mountain View, California)
ABSTRACT An optical coupler includes at least one input waveguide and a plurality of output waveguides. The optical coupler spatially disperses optical signals carried on the input waveguide according to wavelength to the output waveguides. The input waveguides and the output waveguides are arranged to provide crosstalk between optical signals carried on the output waveguides.
FILED Tuesday, July 15, 2014
APPL NO 14/331318
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 5/3539 (20130101)
G01D 5/35316 (20130101)
G01D 5/35383 (20130101) Original (OR) Class

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/246 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2201/088 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/3606 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/2938 (20130101)
G02B 6/12009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678219 Harpring et al.
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) Lawrence J. Harpring (North Augusta, South Carolina);  Eduardo B. Farfan (Aiken, South Carolina);  John R. Gordon (Aiken, South Carolina);  Gerald T. Jannik (North Augusta, South Carolina);  Trevor Q. Foley (Aiken, South Carolina)
ABSTRACT A position determination system and method is provided that may be used for obtaining position and orientation information of a detector in a contaminated room. The system includes a detector, a sensor operably coupled to the detector, and a motor coupled to the sensor to move the sensor around the detector. A CPU controls the operation of the motor to move the sensor around the detector and determines distance and angle data from the sensor to an object. The method includes moving a sensor around the detector and measuring distance and angle data from the sensor to an object at incremental positions around the detector.
FILED Tuesday, August 11, 2015
APPL NO 14/823196
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/167 (20130101)
G01T 1/169 (20130101) Original (OR) Class
G01T 7/00 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678225 Feng
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Patrick L. Feng (Livermore, California)
ABSTRACT An ionizing radiation detector or scintillator system includes a scintillating material comprising an organic crystalline compound selected to generate photons in response to the passage of ionizing radiation. The organic compound has a crystalline symmetry of higher order than monoclinic, for example an orthorhombic, trigonal, tetragonal, hexagonal, or cubic symmetry. A photodetector is optically coupled to the scintillating material, and configured to generate electronic signals having pulse shapes based on the photons generated in the scintillating material. A discriminator is coupled to the photon detector, and configured to discriminate between neutrons and gamma rays in the ionizing radiation based on the pulse shapes of the output signals.
FILED Monday, November 10, 2014
APPL NO 14/537466
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/208 (20130101) Original (OR) Class
G01T 1/2018 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679087 Hamann et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Hendrik F. Hamann (Yorktown Heights, New York);  Sergio Adolfo Bermudez Rodriguez (Croton on Hudson, New York);  Hans-Dieter Wehle (Talheim, Germany)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Hendrik F. Hamann (Yorktown Heights, New York);  Sergio Adolfo Bermudez Rodriguez (Croton on Hudson, New York);  Hans-Dieter Wehle (Talheim, Germany)
ABSTRACT Techniques for modeling a data center are provided. In one aspect, a method for determining data center efficiency is provided. The method includes the following steps. Target parameters for the data center are obtained. Technology pre-requisite parameters for the data center are obtained. An optimum data center efficiency is determined given the target parameters for the data center and the technology pre-requisite parameters for the data center.
FILED Wednesday, September 12, 2012
APPL NO 13/612059
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/50 (20130101)
G06F 17/5004 (20130101) Original (OR) Class
G06F 2217/78 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09679705 Ma et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Beihai Ma (Naperville, Illinois);  Manoj Narayanan (Woodridge, Illinois);  Stephen E. Dorris (LaGrange Park, Illinois);  Uthamalingam Balachandran (Willowbrook, Illinois)
ABSTRACT The present invention provides copper substrate coated with a lead-lanthanum-zirconium-titanium (PLZT) ceramic film, which is prepared by a method comprising applying a layer of a sol-gel composition onto a copper foil. The sol-gel composition comprises a precursor of a ceramic material suspended in 2-methoxyethanol. The layer of sol-gel is then dried at a temperature up to about 250° C. The dried layer is then pyrolyzed at a temperature in the range of about 300 to about 450° C. to form a ceramic film from the ceramic precursor. The ceramic film is then crystallized at a temperature in the range of about 600 to about 750° C. The drying, pyrolyzing and crystallizing are performed under a flowing stream of an inert gas.
FILED Wednesday, February 25, 2015
APPL NO 14/631536
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/491 (20130101)
C04B 35/624 (20130101)
C04B 2235/441 (20130101)
C04B 2235/443 (20130101)
C04B 2235/449 (20130101)
C04B 2235/768 (20130101)
C04B 2235/3227 (20130101)
C04B 2235/3232 (20130101)
C04B 2235/3244 (20130101)
C04B 2235/3296 (20130101)
C04B 2235/6562 (20130101)
C04B 2235/6565 (20130101)
C04B 2235/6584 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/1204 (20130101)
C23C 18/1208 (20130101)
C23C 18/1225 (20130101)
C23C 18/1241 (20130101)
C23C 18/1254 (20130101)
C23C 18/1283 (20130101)
C23C 18/1295 (20130101)
C23C 26/00 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 4/1218 (20130101)
H01G 4/1245 (20130101)
H01G 13/04 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 428/266 (20150115)
Y10T 428/24355 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680414 Chen et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Changyao Chen (Wilmette, Illinois);  Omar Daniel Lopez (Chicago, Illinois);  David A. Czaplewski (Naperville, Illinois)
ABSTRACT This invention comprises a nonlinear micro- and nano-mechanical resonator that can maintain frequency of operation and amplitude of operation for a period of time after all external power has been removed from the device. Utilizing specific nonlinear dynamics of the micromechanical resonator, mechanical energy at low frequencies can be input and stored in higher frequencies modes, thus using the multiple degrees of freedom of the resonator to extend its energy storage capacity. Furthermore, the energy stored in multiple vibrational modes can be used to maintain the resonator oscillating for a fixed period of time, even without an external power supply. This is the first demonstration of an “autonomous” frequency source that can maintain a constant frequency and vibrating amplitude when no external power is provided, making it ideal for applications requiring an oscillator in low power, or limited and intermittent power supplies.
FILED Friday, February 12, 2016
APPL NO 15/042912
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 7/02 (20130101)

Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 5/30 (20130101) Original (OR) Class

Control of Amplification
H03G 3/20 (20130101)

Pulse Technique
H03K 5/003 (20130101)
H03K 5/13 (20130101)
H03K 2005/00286 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680640 Hughes et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Richard John Hughes (Los Alamos, New Mexico);  Jane Elizabeth Nordholt (Los Alamos, New Mexico);  Charles Glen Peterson (Los Alamos, New Mexico)
ABSTRACT Techniques and tools for implementing protocols for secure multi-party communication after quantum key distribution (“QKD”) are described herein. In example implementations, a trusted authority facilitates secure communication between multiple user devices. The trusted authority distributes different quantum keys by QKD under trust relationships with different users. The trusted authority determines combination keys using the quantum keys and makes the combination keys available for distribution (e.g., for non-secret distribution over a public channel). The combination keys facilitate secure communication between two user devices even in the absence of QKD between the two user devices. With the protocols, benefits of QKD are extended to multi-party communication scenarios. In addition, the protocols can retain benefit of QKD even when a trusted authority is offline or a large group seeks to establish secure communication within the group.
FILED Monday, January 05, 2015
APPL NO 14/589261
ART UNIT 2494 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/083 (20130101)
H04L 9/0852 (20130101) Original (OR) Class
H04L 9/0883 (20130101)
H04L 63/062 (20130101)

Wireless Communication Networks
H04W 12/04 (20130101)
H04W 88/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680641 Nordholt et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Jane E. Nordholt (Los Alamos, New Mexico);  Richard John Hughes (Los Alamos, New Mexico);  Raymond Thorson Newell (Santa Fe, New Mexico);  Charles Glen Peterson (Los Alamos, New Mexico);  Danna Rosenberg (Watertown, Massachusetts);  Kevin Peter McCabe (Los Alamos, New Mexico);  Kush T. Tyagi (Los Alamos, New Mexico);  Nicholas Dallmann (Las Alamos, New Mexico)
ABSTRACT Techniques and tools for quantum key distribution (“QKD”) between a quantum communication (“QC”) card, base station and trusted authority are described herein. In example implementations, a QC card contains a miniaturized QC transmitter and couples with a base station. The base station provides a network connection with the trusted authority and can also provide electric power to the QC card. When coupled to the base station, after authentication by the trusted authority, the QC card acquires keys through QKD with a trust authority. The keys can be used to set up secure communication, for authentication, for access control, or for other purposes. The QC card can be implemented as part of a smart phone or other mobile computing device, or the QC card can be used as a fillgun for distribution of the keys.
FILED Monday, April 06, 2015
APPL NO 14/679626
ART UNIT 2433 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/083 (20130101)
H04L 9/0852 (20130101) Original (OR) Class
H04L 9/0897 (20130101)
H04L 9/3231 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 09677681 Ramspacher et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Daniel J. Ramspacher (Washington, District of Columbia);  Caitlin E. Bacha (Bowie, Maryland)
ABSTRACT A valve assembly for an in-space propulsion system includes an inlet tube, an outlet tube, a valve body coupling the inlet tube to the outlet tube and defining a propellant flow path, a valve stem assembly disposed within the valve body, an actuator body coupled to the valve body, the valve stem assembly extending from an interior of the valve body to an interior of the actuator body, and an actuator assembly disposed within the actuator body and coupled to the valve stem assembly, the actuator assembly including a shape memory actuator member that when heated to a transition temperature is configured to enable the valve stem assembly to engage the outlet tube and seal the propellant flow path.
FILED Friday, March 14, 2014
APPL NO 14/211136
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Jet-propulsion Plants
F02K 9/00 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 31/025 (20130101) Original (OR) Class
F16K 31/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678025 Fesmire et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) James E. Fesmire (Titusville, Florida);  Wesley L. Johnson (Titusville, Florida)
ABSTRACT A test apparatus for thermal energy measurement of disk-shaped test specimens has a cold mass assembly locatable within a sealable chamber with a guard vessel having a guard chamber to receive a liquid fluid and a bottom surface to contact a cold side of a test specimen, and a test vessel having a test chamber to receive a liquid fluid and encompassed on one side by a center portion of the bottom surface shared with the guard vessel. A lateral wall assembly of the test vessel is closed by a vessel top, the lateral wall assembly comprising an outer wall and an inner wall having opposing surfaces that define a thermal break including a condensable vapor pocket to inhibit heat transfer through the lateral wall from the guard vessel to the test vessel. A warm boundary temperature surface is in thermal communication with a lower surface of the test specimen.
FILED Thursday, March 06, 2014
APPL NO 14/199768
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 25/72 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680286 McCorkel
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Joel McCorkel (Washington, District of Columbia)
ABSTRACT A tunable laser system includes a tunable laser, an adjustable laser cavity for producing one or more modes of laser light emitted from the tunable laser, a first optical parametric oscillator positioned in a light path of the adjustable laser cavity, and a controller operable to simultaneously control parameters of at least the tunable laser, the first optical parametric oscillator, and the adjustable laser cavity to produce a range of wavelengths emitted from the tunable laser system. A method of operating a tunable laser system includes using a controller to simultaneously control parameters of a tunable laser, an adjustable laser cavity for producing one or more modes of laser light emitted from the tunable laser, and a first optical parametric oscillator positioned in a light path of the adjustable laser cavity, to produce a range of wavelengths emitted from the tunable laser system.
FILED Tuesday, September 29, 2015
APPL NO 14/868898
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/48 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/39 (20130101)
G02F 1/3551 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/105 (20130101)
H01S 3/0811 (20130101)
H01S 3/0813 (20130101)
H01S 3/1083 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09680527 Lin et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Michael R. Lin (Ellicott City, Maryland);  David J. Petrick (Severna Park, Maryland);  Kevin M. Ballou (Highland, Maryland);  Daniel C. Espinosa (Tampa, Florida);  Edward F. James (Westminster, Maryland);  Matthew A. Kliesner (Madison, Alabama)
ABSTRACT Embodiments may provide a radiation hardened 10BASE-T Ethernet interface circuit suitable for space flight and in compliance with the IEEE 802.3 standard for Ethernet. The various embodiments may provide a 10BASE-T Ethernet interface circuit, comprising a field programmable gate array (FPGA), a transmitter circuit connected to the FPGA, a receiver circuit connected to the FPGA, and a transformer connected to the transmitter circuit and the receiver circuit. In the various embodiments, the FPGA, transmitter circuit, receiver circuit, and transformer may be radiation hardened.
FILED Wednesday, September 16, 2015
APPL NO 14/855992
ART UNIT 2634 — Digital Communications
CURRENT CPC
Pulse Technique
H03K 19/17744 (20130101)

Transmission
H04B 3/54 (20130101) Original (OR) Class
H04B 3/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 09677984 Zachariah et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) University of Maryland (College Park, Maryland)
ASSIGNEE(S) University of Maryland (College Park, Maryland)
INVENTOR(S) Michael R. Zachariah (Potomac, Maryland);  Mingdong Li (Germantown, Maryland);  George W. Mulholland (Gaithersburg, Maryland)
ABSTRACT A method for extracting shape information for particles with similar shape and corresponding system of a tandem differential mobility analyzer (DMA) and pulse field differential mobility analyzer (PFDMA) system, that executes at least generating a steady state aerosol concentration; passing aerosol flow from the aerosol concentration thru a bipolar charger to produce a known charge distribution; passing aerosol thru a DMA with set sheath and aerosol flows and a set voltage to generate a mono-mobility aerosol; passing mono-mobility aerosol thru a PFDMA system; and measuring mobility as a function of electric field by varying the duty cycle of the pulse in the PFDMA system. Alternatively, the method and system relate to separating particles with different shapes by adjusting the duty cycle of the pulse to reach a higher or lower electric field than in the DMA in which the mono-mobility aerosol was generated; and separating particles based on shape.
FILED Monday, February 02, 2015
APPL NO 14/611904
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/0266 (20130101) Original (OR) Class
G01N 2015/0277 (20130101)
G01N 2015/0288 (20130101)
G01N 2015/0294 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678045 Zhu et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S) Board of Regents, The University Of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Jinying Zhu (Round Rock, Texas);  Michael R. Haberman (Austin, Texas);  Xiaowei Dai (Austin, Texas)
ABSTRACT Provided are devices, systems, and methods for the testing of materials and structures. For example, the devices, systems, and methods are optionally used for the non-destructive testing of a material or structure. Furthermore, the devices, systems, and methods may optionally use a high-amplitude, air-coupled acoustic source for non-destructive testing of materials and structures.
FILED Friday, August 30, 2013
APPL NO 14/014877
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/34 (20130101) Original (OR) Class
G01N 29/2431 (20130101)
G01N 29/2456 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/28 (20130101)
G10K 15/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678473 Rosen et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) CELLOPTIC, INC. (Rockville, Maryland)
ASSIGNEE(S) CELLOPTIC, INC. (Rockville, Maryland)
INVENTOR(S) Joseph Rosen (Omer, Illinois);  Gary Brooker (Rockville, Maryland);  Nisan Siegel (Silver Spring, Maryland)
ABSTRACT An apparatus for producing a hologram includes a collimation lens configured to receive incoherent light emitted from an object; a spatial light modulator (SLM) that includes at least one diffractive lens which is configured to receive the incoherent light from the collimation lens and split the incoherent light into two beams that interfere with each other; and a camera configured to record the interference pattern of the two beams to create a hologram, wherein a ratio between a distance from the SLM to the camera and a focal length of the diffractive lens is greater than 1.
FILED Friday, December 07, 2012
APPL NO 14/363380
ART UNIT 2872 — Optics
CURRENT CPC
Holographic Processes or Apparatus
G03H 1/0005 (20130101) Original (OR) Class
G03H 1/06 (20130101)
G03H 1/041 (20130101)
G03H 1/0443 (20130101)
G03H 2001/005 (20130101)
G03H 2001/0224 (20130101)
G03H 2001/0447 (20130101)
G03H 2223/23 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 09675902 Lipkens et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) FloDesign Sonics, Inc. (Wilbraham, Massachusetts)
ASSIGNEE(S) FLODESIGN SONICS, INC. (Wilbraham, Massachusetts)
INVENTOR(S) Bart Lipkens (Hampden, Massachusetts);  Jason Dionne (Simsbury, Massachusetts);  Ari Mercado (Agawam, Massachusetts);  Brian Dutra (Rockland, Massachusetts);  Walter M. Presz, Jr. (Wilbraham, Massachusetts);  Thomas J. Kennedy, III (Wilbraham, Massachusetts);  Louis Masi (Longmeadow, Massachusetts)
ABSTRACT An acoustic standing wave is utilized to separate components from a multi-component fluid, such as oil from an oil-water mixture, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allows for trapping of the oil as the oil coalesces, agglomerates, and becomes more buoyant than the water.
FILED Tuesday, January 19, 2016
APPL NO 15/000573
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 17/04 (20130101) Original (OR) Class
B01D 43/00 (20130101)

Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/0644 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 47/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09676779 Schwiebert et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) DISCOVERYBIOMED, INC. (Birmingham, Alabama)
ASSIGNEE(S) DiscoveryBiomed, Inc. (Birmingham, Alabama)
INVENTOR(S) Erik Schwiebert (Birmingham, Alabama);  John Streiff (Birmingham, Alabama);  John Dixon (Leicestershire, United Kingdom);  Hongwu Gao (Shanghai, China PRC)
ABSTRACT Novel CFTR corrector compounds that are effective in rescuing halide efflux, delF508-CFTR protein processing, and apical functional chloride ion transport in a cell are provided. Also provided are methods for treating protein folding disorders (e.g., cystic fibrosis). The methods include administering a CFTR corrector compound or pharmaceutically acceptable salt or prodrug thereof. Methods of rescuing halide efflux in a cell, correcting a processing defect of a delF508-CFTR protein in a cell, and correcting functional delF508-CFTR chloride channels in a cell are also provided.
FILED Wednesday, November 20, 2013
APPL NO 14/646063
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101)
C07D 487/04 (20130101) Original (OR) Class
C07D 498/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09677110 Cunningham
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Wayne State University (Detroit, Michigan)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Philip R. Cunningham (Troy, Michigan)
ABSTRACT The “instant evolution” system was initially developed in E. coli, primarily because of the ease with which this organism can be genetically manipulated. Because many of the functionally important regions of rRNA are conserved among bacteria, drug leads developed against conserved targets in the E. coli system may produce broad-spectrum anti-infectives. In order to develop a system to produce narrow-spectrum anti-infectives, herein we disclose methods for identifying functional mutant P. aeruginosa ribosomes suitable as drug targets and for identifying drug candidates that do not bind to the human 16S rRNA.
FILED Monday, June 22, 2015
APPL NO 14/746043
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101)
C12N 15/70 (20130101)
C12N 15/1034 (20130101)
C12N 15/1086 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/10 (20130101)
C12Q 1/18 (20130101) Original (OR) Class
C12Q 1/025 (20130101)
C12Q 1/6876 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/21 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 09678152 Maliuk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
National Security Agency (NSA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Dzmitry S. Maliuk (Addison, Texas);  Franco Stellari (Waldwick, New Jersey);  Alan J. Weger (Mohegan Lake, New York);  Peilin Song (Lagrangeville, New York)
ABSTRACT A scan chain latch circuit, a method of operating a latch circuit in a scan chain, and a computer-readable medium having stored thereon a data structure defining a scan chain latch circuit for instantiation on a semiconductor die are disclosed. In an embodiment, the scan chain latch circuit comprises a first latch for holding one data value, a second latch for holding another data value, and a multiplexor. The one data value is applied to a first data input of the multiplexor and the another data value is applied to a second data input of the multiplexor. An alternating clock signal is applied to a select input of the multiplexor to control the output of the multiplexor, wherein the output of the multiplexor toggles between the two data values held in the two latches at a defined frequency.
FILED Tuesday, April 26, 2016
APPL NO 15/138737
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/3177 (20130101)
G01R 31/31723 (20130101) Original (OR) Class
G01R 31/31727 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678289 Schultz et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Mark D. Schultz (Ossining, New York);  Shurong Tian (Mount Kisco, New York)
ABSTRACT An optical coupling system includes a substrate, an electronic die comprising a plurality of coupling holes for passing light, an optical element die attached to a bottom surface of the electronic die, the electronic die attached to the substrate such that the electronic die covers a cavity in the substrate and the optical element die resides within the cavity of the substrate. The system may also include a thermally conductive lid that covers and contacts the electronic die and the substrate and has a coupling aperture that enables light that passes through the coupling holes to pass through the thermally conductive lid. The system may also include an optical cable coupler comprising a coupling section that laterally fits within the coupling aperture and a body section disposed above the coupling section that is laterally larger than the coupling section. A method for providing the above system is also disclosed herein.
FILED Wednesday, December 02, 2015
APPL NO 14/956484
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/4242 (20130101)
G02B 6/4244 (20130101)
G02B 6/4245 (20130101)
G02B 6/4267 (20130101)
G02B 6/4269 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Education (ED) 

US 09677186 Braun et al.
FUNDED BY
Department of Education (ED)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Trevor Braun (Seattle, Washington);  Daniel T. Schwartz (Seattle, Washington)
ABSTRACT A bipolar electrochemistry printer and method are disclosed wherein electrolytic deposition onto a conductive substrate is accomplished by inducing ionic current in an electrolytic cell disposed above the substrate to undergo charge transfer at the conductive substrate, such that a portion of the substrate becomes a bipolar electrode. The ohmic current in the substrate undergoes a second charge transfer back to ionic current and returning to the cathode of the electrolytic cell. In an alternative embodiment the printing is similarly accomplished by electrolytic etching.
FILED Tuesday, March 24, 2015
APPL NO 14/666554
ART UNIT 1756 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/12 (20130101)
C25D 3/38 (20130101)
C25D 5/026 (20130101) Original (OR) Class
C25D 17/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 09678024 Wilson et al.
FUNDED BY
Department of Homeland Security (DHS)
Countering Weapons of Mass Destruction Office (CWMD)
Domestic Nuclear Detection Office (DNDO)
Science and Technology Directorate (DHS-ST)
APPLICANT(S) Passport Systems, Inc. (Billerica, Massachusetts)
ASSIGNEE(S) Passport Systems, Inc. (Billerica, Massachusetts)
INVENTOR(S) Cody M. Wilson (Watertown, Massachusetts);  William Bertozzi (Lexington, Massachusetts);  Daniel L. Higgs (Weymouth, Massachusetts);  Stephen E. Korbly (Acton, Massachusetts);  Robert J. Ledoux (Harvard, Massachusetts)
ABSTRACT Methods and systems are disclosed wherein neutrons are produced by a photon induced process 2D(γ,n) and the ensuing neutrons are thermalized and captured by hydrogen producing a 2.223 MeV gamma that is used to identify and quantify the presence of hydrogen and which, when combined with NRF signals from certain isotopes, can be used to establish the nature of a hydrogenous compound or a mixture of hydrogenous materials or a mixture of hydrogenous materials with other non-hydrogenous materials. The method is useful to establish, e.g., the presence and quantification of explosives, toxic substances and general contraband as well as the flow of materials in a production line or shipping venue.
FILED Friday, April 08, 2016
APPL NO 15/094490
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/223 (20130101)
G01N 23/2208 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 09680139 Hill et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Transit Administration (FTA)
APPLICANT(S) Proterra Inc. (Greenville, South Carolina)
ASSIGNEE(S) Proterra Inc. (Greenville, South Carolina)
INVENTOR(S) Dale Hill (New Braunfels, Texas);  Michael Walker (Daly City, California);  Shaun Onorato (Superior, Colorado);  Donald Morris (Littleton, Colorado);  Stephen Misencik (Raleigh, North Carolina);  John Winkel (Thornton, Colorado)
ABSTRACT The invention provides for a high occupancy or heavy-duty vehicle with a battery propulsion power source, which may include lithium titanate batteries. The vehicle may be all-battery or may be a hybrid, and may have a composite body. The vehicle battery system may be housed within the floor of the vehicle and may have different groupings and arrangements.
FILED Monday, January 11, 2016
APPL NO 14/992900
ART UNIT 3618 — Semiconductors/Memory
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 1/04 (20130101)
B60K 6/20 (20130101)
B60K 2001/0438 (20130101)

Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 3/0046 (20130101)
B60L 11/126 (20130101)
B60L 11/185 (20130101)
B60L 11/1853 (20130101)
B60L 11/1864 (20130101)
B60L 11/1874 (20130101)
B60L 11/1877 (20130101)
B60L 11/1879 (20130101)
B60L 2200/18 (20130101)
B60L 2200/26 (20130101)
B60L 2200/28 (20130101)
B60L 2270/40 (20130101)

Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for
B60R 16/04 (20130101)

Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 10/24 (20130101)

Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology
B60Y 2200/14 (20130101)
B60Y 2200/15 (20130101)
B60Y 2200/1432 (20130101)

Motor Vehicles; Trailers
B62D 29/00 (20130101)
B62D 29/02 (20130101)
B62D 47/02 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/206 (20130101)
H01M 2/1077 (20130101)
H01M 2/1083 (20130101) Original (OR) Class
H01M 4/485 (20130101)
H01M 10/42 (20130101)
H01M 10/052 (20130101)
H01M 10/613 (20150401)
H01M 10/4207 (20130101)
H01M 2010/4271 (20130101)
H01M 2220/20 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/6217 (20130101)
Y02T 10/6269 (20130101)
Y02T 10/7005 (20130101)
Y02T 10/7011 (20130101)
Y02T 10/7061 (20130101)
Y02T 10/7072 (20130101)
Y02T 10/7077 (20130101)
Y02T 90/14 (20130101)
Y02T 90/121 (20130101)
Y02T 90/128 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Treasury (TREASURY) 

US 09675295 Kron et al.
FUNDED BY
Department of the Treasury (TREASURY)
Internal Revenue Service (IRS)
APPLICANT(S) BioFluid Technology, Inc. (Bryn Mawr, Pennsylvania)
ASSIGNEE(S) BioFluid Technology, Inc. (Bryn Mawr, Pennsylvania)
INVENTOR(S) Reuben E Kron (Bryn Mawr, Pennsylvania);  Stephen J Kron (Chicago, Illinois)
ABSTRACT Provided are devices and methods suitable for immobilizing tissue and for use in non-invasive methods of assessing lower urinary tract symptoms as well as in surgical application.
FILED Friday, January 15, 2016
APPL NO 14/996373
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/205 (20130101)
A61B 5/208 (20130101)
A61B 5/6834 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 09675931 Holmes et al.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S) ENERGY AND ENVIRONMENTAL RESEARCH CENTER FOUNDATION (Grand Forks, North Dakota)
ASSIGNEE(S) Energy and Environmental Research Center Foundation (Grand Forks, North Dakota)
INVENTOR(S) Michael J. Holmes (Thompson, North Dakota);  John H. Pavlish (East Grand Forks, Minnesota);  Edwin S. Olson (Grand Forks, North Dakota)
ABSTRACT A system and method is provided for the removal of mercury from flue gas. Effective removal of mercury is obtained by oxidation of elemental mercury, with highly reactive halogen species derived from dissociation of halogen compounds at moderate temperatures brought into contact with the flue gas with or without the addition of carbon.
FILED Monday, October 12, 2015
APPL NO 14/880463
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/64 (20130101) Original (OR) Class
B01D 2251/404 (20130101)
B01D 2257/602 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US D789649 Spears et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washintgon, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Michael LeRoy Spears (Chantilly, Virginia);  Joel L. Dewnandan (Bladenburg, Maryland);  Donald Eugene Irwin (Fredericksburg, Virginia);  Joram Shenhar (Fairfax, Virginia);  William Albert Tartal (Baltimore, Maryland)
ABSTRACT
FILED Friday, September 18, 2015
APPL NO 29/539922
ART UNIT 2919 — Design
CURRENT CPC
Miscellaneous
D99/28
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 09678231 Davis et al.
FUNDED BY
APPLICANT(S) Robert Terry Davis (Satellite Beach, Florida);  Paul Armin Nyffenegger (Rockledge, Florida);  Mark Andrew Tinker (Merritt Island, Florida);  Jonathan Marshall Volk (Melbourne, Florida);  Kyle Burton Johnston (Melbourne, Florida);  Paul Thurston Richards (Melbourne, Florida)
ASSIGNEE(S) Quantum Technology Sciences, Inc. (Cocoa Beach, Florida)
INVENTOR(S) Robert Terry Davis (Satellite Beach, Florida);  Paul Armin Nyffenegger (Rockledge, Florida);  Mark Andrew Tinker (Merritt Island, Florida);  Jonathan Marshall Volk (Melbourne, Florida);  Kyle Burton Johnston (Melbourne, Florida);  Paul Thurston Richards (Melbourne, Florida)
ABSTRACT Methods or systems for identifying seismic or acoustic signals of interest originating with moving motorized vehicles or footstep movement or stationary or moving machinery. A related system for monitoring an area includes a plurality of sensing devices each comprising a frame and a piezo-electric sensor element. A monitoring device is coupled to receive information from each of the sensing devices. One method includes providing a processing chain coupled to receive signal data from a sensor device which receives the signals, including a detection stage, a Joint Time Frequency (JTF) domain stage, and a classification stage. The detection stage identifies presence of signals that emerge from the background. The JTF domain stage estimates the state of the signals of interest over time. The classification stage assesses the previously derived information to form a decision about source identity. In one embodiment, the detector stage performs detections on a single cycle basis.
FILED Monday, March 19, 2012
APPL NO 13/423607
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/80 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/00 (20130101)
G01V 1/34 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09678331 Miller
FUNDED BY
APPLICANT(S) RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S) RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S) Kirk A. Miller (Dallas, Texas)
ABSTRACT An optical path switching device is configured to selectively direct electromagnetic radiation toward one detector of a plurality of detectors. The switching device includes a platform, a mirror mount rotatably mounted on the platform by a bearing, a mirror coupled to the mirror mount, and an active actuator configured to rotate the mirror mount with respect to the platform a predetermined amount to direct electromagnetic radiation toward a desired detector.
FILED Thursday, January 28, 2016
APPL NO 15/009292
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/0816 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/2254 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 13, 2017.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20170613.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital