FedInvent™ Patents
Patent Details for Tuesday, June 20, 2017
This page was updated on Monday, March 27, 2023 at 05:14 AM GMT
Department of Health and Human Services (HHS)
| US 09681646 | Lawrence et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Jeanne B. Lawrence (Mapleville, Rhode Island); Jun Jiang (Shrewsbury, Massachusetts); Lisa L. Hall (Framingham, Massachusetts) |
| ABSTRACT | Methods and compositions for reducing expression of genes on Chromosome 21 (“Chr 21”) by targeting an XIST transgene to the Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) gene or a Regulator of calcineurin 1 (RCAN1) gene, and cells and transgenic animals comprising an XIST transgene inserted into a DYRK1A or RCAN1 allele, e.g., cells and animals trisomic for human Chr 21 and mouse Chr 16. |
| FILED | Monday, March 17, 2014 |
| APPL NO | 14/215997 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class Peptides C07K 14/4703 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 9/12 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09681647 | Chen et al. |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Huanhuan Chen (Flushing, New York); Steven M. Lipkin (Scarsdale, New York); Xiling Shen (Ithaca, New York) |
| ABSTRACT | Provided are compositions and methods that involve cancer cells which are modified so that they can form orthotopic tumors in a non-human mammal, and wherein metastasis of the tumor can be controlled. The cancer cells, which may be human cancer cells, are modified so that expression of a human chemokine receptor can be modulated. Modulating expression of the human chemokine receptor allows selective initiation of metastasis. Kits which contain the modified cancer cells are provided. A method for identifying agents which can inhibit metastasis using non-human mammals having orthotopic tumors formed using the modified cancer cells is also included. |
| FILED | Wednesday, July 03, 2013 |
| APPL NO | 14/412312 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 67/0278 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Peptides C07K 14/7158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2310/531 (20130101) C12N 2740/15043 (20130101) C12N 2830/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09681808 | Donohue et al. |
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| APPLICANT(S) | Signal Solutions, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | Signal Solutions, LLC (Lexington, Kentucky) |
| INVENTOR(S) | Kevin Donohue (Lexington, Kentucky); Bruce O'Hara (Lexington, Kentucky); Sridhar Sunderam (Lexington, Kentucky); Farid Yaghouby (Lexington, Kentucky) |
| ABSTRACT | Monitoring behavior of a rodent within a cage includes applying a vibration stimulus to a component of the cage and after applying the vibration stimulus, sensing a signal from a piezoelectric sensor within the cage, the sensed signal indicative of a behavioral response of the rodent. A plurality of attributes of the signal can be determined and the attributes can then be stored in a manner that associates the behavioral response of the rodent with the vibration stimulus. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 14/870286 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/0051 (20130101) Original (OR) Class A61B 5/4809 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09681835 | Karmali et al. |
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| APPLICANT(S) | Faisal Karmali (Cambridge, Massachusetts); Csilla Haburcakova (Somerville, Massachusetts); Daniel Michael Merfeld (Lincoln, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| INVENTOR(S) | Faisal Karmali (Cambridge, Massachusetts); Csilla Haburcakova (Somerville, Massachusetts); Daniel Michael Merfeld (Lincoln, Massachusetts) |
| ABSTRACT | A method for predicting whether a patient is afflicted by a vestibular disorder includes assaying vestibular noise; identifying a characteristic of the vestibular noise; and at least in part on the basis of the characteristic of the vestibular noise, providing information for predicting that a patient has a vestibular disorder. |
| FILED | Tuesday, November 15, 2011 |
| APPL NO | 13/885263 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1116 (20130101) A61B 5/1128 (20130101) A61B 5/4023 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09681853 | Vilkomerson |
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| APPLICANT(S) | DVX, LLC (Princeton, New Jersey) |
| ASSIGNEE(S) | DVX, LLC (Princeton, New Jersey) |
| INVENTOR(S) | David Vilkomerson (Princeton, New Jersey) |
| ABSTRACT | The velocity of fluids containing particles that scatter ultrasound can be measured by determining the Doppler shift of the ultrasound scattered by the particles in the fluid. Measuring fluid flow in cylindrical vessels such as blood vessels is an important use of Doppler ultrasound. This invention teaches using various configurations of cylindrical diffraction-grating transducers and cylindrical non-diffraction-grating transducers that suppress the Doppler shift from non-axial components of fluid velocity while being sensitive to the Doppler shift produced by axial velocity components. These configurations thus provide accurate measurement of the net flow down the vessel, even when the fluid flow is curved or not parallel to the vessel wall. |
| FILED | Tuesday, September 02, 2014 |
| APPL NO | 14/475541 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/06 (20130101) A61B 8/488 (20130101) Original (OR) Class A61B 8/0891 (20130101) A61B 8/4455 (20130101) A61B 8/4483 (20130101) A61B 8/4494 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09681893 | Panjabi et al. |
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| APPLICANT(S) | Yale University (New Haven, Connecticut); Rachiotek, LLC (Wellesley, Massachusetts) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut); Rachiotek, LLC (Cambridge, Massachusetts) |
| INVENTOR(S) | Manohar M. Panjabi (Concord, Massachusetts); Jens P. Timm (Carlsbad, California); George Malcolmson, II (New Haven, Connecticut) |
| ABSTRACT | Spine stabilization devices, systems and methods are provided in which a single resilient member or spring is disposed on an elongate element that spans two attachment members attached to different spinal vertebrae. The elongate element passes through at least one of the two attachment members, permitting relative motion therebetween, and terminates in a stop or abutment. A second resilient member is disposed on the elongate element on an opposite side of the sliding attachment member, e.g., in an overhanging orientation. The two resilient members are capable of applying mutually opposing urging forces, and a compressive preload can be applied to one or both of the resilient members. |
| FILED | Friday, April 10, 2015 |
| APPL NO | 14/683270 |
| ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/702 (20130101) A61B 17/7007 (20130101) A61B 17/7026 (20130101) Original (OR) Class A61B 17/7028 (20130101) A61B 17/7041 (20130101) A61B 17/7049 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/22 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682006 | Goldfarb et al. |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Michael Goldfarb (Franklin, Tennessee); Ryan J. Farris (Nashville, Tennessee); Hugo A. Quintero (Irvine, California) |
| ABSTRACT | A apparatus includes an a exoskeleton system with a plurality of sensors for generating signals indicating a current motion and a current arrangement of at least the exoskeleton system, a hip segment, and at least one lower limb. The lower limb includes thigh and shank segments for coupling to a lateral surface of a user's leg. The thigh segment includes a first powered joint coupling the thigh segment to the hip segment, a second powered joint coupling the thigh segment to the shank segment, and a controller coupled to the sensors, the first powered joint, and the second powered joint. The controller is configured for determining a current state of the exoskeleton system and a current intent of the user based on the signals and generating control signals for the first and second powered joints based on the current state and the current intent. |
| FILED | Wednesday, October 09, 2013 |
| APPL NO | 14/049494 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/14 (20130101) A61G 7/109 (20130101) A61G 7/1017 (20130101) A61G 7/1096 (20130101) A61G 2203/36 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0262 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 3/02 (20130101) A61H 3/04 (20130101) A61H 2201/10 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/1463 (20130101) A61H 2201/1628 (20130101) A61H 2201/1676 (20130101) A61H 2201/5005 (20130101) A61H 2201/5007 (20130101) A61H 2201/5069 (20130101) A61H 2201/5084 (20130101) A61H 2201/5097 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0452 (20130101) A61N 1/36003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682060 | Hergenrother et al. |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Paul J. Hergenrother (Champaign, Illinois); Karson S. Putt (Champaign, Illinois); Rahul Palchaudhuri (Cambridge, Massachusetts) |
| ABSTRACT | Apoptosis is generally believed to be a process that requires several hours, in contrast to non-programmed forms of cell death that can occur in minutes. Our findings challenge the time-consuming nature of apoptosis. We describe herein the discovery and characterization of a small molecule, named Raptinal, which initiates intrinsic pathway caspase-dependent apoptosis within minutes, in multiple different cell lines. Comparison to a mechanistically diverse panel of apoptotic stimuli reveals Raptinal-induced apoptosis proceeds with unparalleled speed. The rapid phenotype enabled identification of the critical roles of mitochondrial voltage-dependent anion channel function, mitochondrial membrane potential/coupled respiration, and mitochondrial complex I, III and IV function for apoptosis induction. Use of Raptinal in whole organisms demonstrates its utility to study apoptosis in vivo for a variety of applications. Overall, rapid inducers of apoptosis are powerful tools that will be used in a variety of settings to generate further insight into the apoptotic machinery. |
| FILED | Monday, October 17, 2016 |
| APPL NO | 15/295921 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 31/343 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682070 | Yan et al. |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Chen Yan (Rochester, New York); Jian-Dong Li (Marietta, Georgia); Bradford Berk (Rochester, New York); Kye-Im Jeon (Rochester, New York); Xiangbin Xu (Rochester, New York) |
| ABSTRACT | Pharmaceutical compositions and methods for treating or preventing an inflammatory condition in a patient are disclosed. The pharmaceutical compositions and methods include the use of vincamine or a vincamine derivative, either alone or in combination with one or more additional therapeutic agents, including a steroid (preferably a corticosteroid), an angiotensin II receptor (type 1) antagonist, an angiotensin-converting enzyme (ACE) inhibitor, and a non-steroidal anti-inflammatory drug. |
| FILED | Tuesday, December 15, 2015 |
| APPL NO | 14/970028 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0046 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/4375 (20130101) Original (OR) Class A61K 31/4375 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682078 | Botchwey, III et al. |
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| APPLICANT(S) | Edward A. Botchwey, III (Charlottesville, Virginia); Mary J. Laughlin (Crozet, Virginia); Kevin R. Lynch (Charlottesville, Virginia); Anusuya Das (Charlottesville, Virginia); Anthony Awojoodu (Burtonsville, Maryland) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Edward A. Botchwey, III (Charlottesville, Virginia); Mary J. Laughlin (Crozet, Virginia); Kevin R. Lynch (Charlottesville, Virginia); Anusuya Das (Charlottesville, Virginia); Anthony Awojoodu (Burtonsville, Maryland) |
| ABSTRACT | The present application discloses strategies to recruit and mobilize stem cells using S1P receptor selective agonists and antagonists as wells as regulators of chemokine receptors. In an in vivo ischemic model, S1P1/S1P3 activation with FTY720 impeded inflammatory cell infiltration and recruited endothelial progenitor cells (EPCs) with the potential to increase microvascular remodeling. S1P3 expression on marrow-derived cells was essential for this remodeling. Concurrent systemic S1P3 and CXCR4 antagonism mobilized hematopoietic stem cells (HSCs) with the ability to engraft and repopulate blood cells. Pre-treatment of donor HSCs with FTY720 increased homing toward SDF-1 and improved engraftment in marrow. FTY720-coated bone allografts coupled with systemic administration of VPC01091 enhanced bone allograft integration and new bone formation in bone defects. MSCs pre-treated with FTY720 exhibited increased migration toward SDF-1, a CXCR4+ ligand. The results show that S1P is a very powerful role player in pharmacological marrow-derived stem cell mobilization and recruitment. |
| FILED | Friday, March 16, 2012 |
| APPL NO | 14/006053 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/66 (20130101) A61K 31/135 (20130101) A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/395 (20130101) A61K 31/395 (20130101) A61K 31/495 (20130101) Original (OR) Class A61K 31/4164 (20130101) A61K 31/4164 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682085 | Abdel-Meguid et al. |
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| APPLICANT(S) | Shifa Biomedical Corporation (Malvern, Pennsylvania) |
| ASSIGNEE(S) | Shifa Biomedical Corporation (Malvern, Pennsylvania) |
| INVENTOR(S) | Sherin Salaheldin Abdel-Meguid (Exton, Pennsylvania); Nabil Elshourbagy (Chester, Pennsylvania); Harold Meyers (Weston, Pennsylvania); Shaker A. Mousa (Wynantskill, New York) |
| ABSTRACT | Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), as well as therapeutic methods for use of such compounds to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia. Examples of compounds include thiadiazole, isoxazole, 1,2,4-triazole, thiazole, indole, pyrazole, and pyrrolinone derivatives. |
| FILED | Tuesday, March 11, 2014 |
| APPL NO | 14/767133 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/404 (20130101) A61K 31/415 (20130101) A61K 31/426 (20130101) A61K 31/433 (20130101) A61K 31/4015 (20130101) A61K 31/4155 (20130101) A61K 31/4178 (20130101) A61K 31/4196 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/5377 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682088 | Nieman et al. |
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| APPLICANT(S) | LABORATOIRE HRA-PHARMA (Paris, France); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
| ASSIGNEE(S) | LABORATOIRE HRA-PHARMA (Paris, France); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
| INVENTOR(S) | Lynnette Nieman (Bethesda, Maryland); Andre Ulmann (Paris, France); Diana Blithe (Silver Spring, Maryland); Erin Gainer (Paris, France) |
| ABSTRACT | The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-N,N-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/or for reducing the size of uterine fibroids. |
| FILED | Thursday, October 01, 2015 |
| APPL NO | 14/872320 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/20 (20130101) A61K 31/57 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682090 | Morrissey |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Colm Morrissey (Seattle, Washington) |
| ABSTRACT | Methods for treating a subject having a prostate cancer bone metastasis are disclosed. Methods for prophylactically treating a subject at risk of developing a prostate cancer bone metastasis are also disclosed. The methods for treating a subject having, or at risk of developing, a prostate cancer bone metastasis may include administering a prostatic acid phosphatase inhibiting agent to the subject. The methods for treating a subject having, or at risk of developing, a prostate cancer bone metastasis may also include administering a phosphonic acid to the subject. Further, the phosphonic acid may include a benzylaminophosphonic acid, such as [phenyl[(phenylmethyl)amino]methyl]-phosphonic acid). |
| FILED | Friday, November 13, 2015 |
| APPL NO | 14/941281 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/662 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682105 | Le et al. |
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| FUNDED BY |
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| APPLICANT(S) | Anh D. Le (La Mirada, California); Qunzhou Zhang (San Gabriel, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Anh D. Le (La Mirada, California); Qunzhou Zhang (San Gabriel, California) |
| ABSTRACT | Disclosed are methods of polarizing macrophages to exhibit M2 phenotype, including introducing an effective amount of gingiva-derived mesenchymal stem cells to an environment comprising a population of macrophages such that the macrophages are in fluid communication with the gingiva-derived mesenchymal stem cells. Also disclosed are methods of promoting cutaneous wound healing including administering to a patient an effective amount of human gingiva-derived mesenchymal stem cells, thereby resulting in at least one of accelerated wound closure, rapid re-epithelialization, improved angiogenesis and improved tissue remodeling relative to untreated controls. Also disclosed are methods for attenuating contact hypersensitivity in a patient, the methods including administering to a patient an effective amount of human gingiva-derived mesenchymal stem cells at a time at least timeframe selected from the group consisting of before sensitization, after sensitization and before challenge and after challenge, thereby attenuating contact hypersensitivity. |
| FILED | Thursday, July 14, 2011 |
| APPL NO | 13/809876 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682106 | Kasahara et al. |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Noriyuki Kasahara (Miami, Florida); Robert H. Schiestl (Encino, California); Katrin Hacke (Los Angeles, California); Akos Szakmary (Vienna, Austria); Gay M. Crooks (Sherman Oaks, California) |
| ABSTRACT | A method of radiation-free hematopoietic stem cell (HSC) transplantation comprises administering to a mammalian subject one or two doses of 2 to 10 mg/kg body weight of a purine base analog, such as 6TG as a pre-conditioning step. The method further comprises engrafting into the subject hypoxanthine-guanine phosphoribosyltransferase (HPRT)-deficient donor HSCs within 48 to 72 hours of the pre-conditioning step; and administering to the subject about 1 to 5 mg/kg of the purine base analog every two to four days for two to eight weeks following the engrafting step. The method is performed in the absence of pre-conditioning via radiation. The subject is therefore not treated with myeloablative radiation in preparation for transplantation, and thus the subject is free of myeloablative radiation-induced toxicity. |
| FILED | Monday, May 16, 2016 |
| APPL NO | 15/155776 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 2035/124 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682107 | Shi et al. |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Songtao Shi (Los Angeles, California); Pamela Gehron Robey (Bethesda, Maryland); Stan Gronthos (South Australia, Australia); Masako Miura (Kyoto, Japan) |
| ABSTRACT | The invention generally relates to postnatal dental stem cells and methods for their use. More specifically, the invention relates in one aspect to postnatal dental pulp stem cells, use of the cells to generate dentin, and differentiation of the cells. In another aspect, the invention relates to human postnatal deciduous dental pulp multipotent stem cells, use of the cells to generate dentin, and differentiation of the cells. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/869565 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/30 (20130101) Original (OR) Class A61K 47/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) C12N 5/0618 (20130101) C12N 5/0654 (20130101) C12N 5/0664 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2506/1361 (20130101) C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682120 | Polk et al. |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | D. Brent Polk (Nashville, Tennessee); Fang Yan (Franklin, Tennessee) |
| ABSTRACT | The present invention provides therapeutic and prophylactic compositions for use in treating and preventing disorders involved epithelial cell apoptosis, such as gastrointestinal disorders (e.g., inflammatory bowel disease, Crohn's disease or ulcerative colitis) in a subject, such as a human patient. |
| FILED | Monday, August 24, 2015 |
| APPL NO | 14/833611 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/164 (20130101) Original (OR) Class Peptides C07K 14/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682133 | Crystal et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ronald G. Crystal (New York, New York); Bishnu De (New Hyde Park, New York); Martin Hicks (New York, New York); Jonathan Rosenberg (Cranbury, New Jersey); Stephen M. Kaminsky (Bronx, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Ronald G. Crystal (New York, New York); Bishnu De (New Hyde Park, New York); Martin Hicks (New York, New York); Jonathan Rosenberg (Cranbury, New Jersey); Stephen M. Kaminsky (Bronx, New York) |
| ABSTRACT | The invention is directed to an adenovirus-antigen conjugate comprising (a) a disrupted adenovirus with a coat protein and (b) an antigen conjugated to the coat protein of the disrupted adenovirus, as well as a conjugate comprising (a) a disrupted adenovirus with a coat protein and (b) an antigen conjugated to the coat protein of the disrupted adenovirus. The invention also provides a method of inducing an immune response against an antigen in a human using the aforementioned conjugates. The invention further provides an adeno-associated viral vector comprising a nucleic acid sequence which encodes an antibody directed against cocaine. |
| FILED | Thursday, March 17, 2011 |
| APPL NO | 13/635635 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0013 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/62 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) A61K 2039/6075 (20130101) A61K 2039/55511 (20130101) Peptides C07K 16/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/10342 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682139 | Manoharan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARBUTUS BIOPHARMA CORPORATION (Burnaby, Canada) |
| ASSIGNEE(S) | Arbutus Biopharma Corporation (Burnaby, British Columbia, Canada) |
| INVENTOR(S) | Muthiah Manoharan (Cambridge, Massachusetts); Kallanthottathil G. Rajeev (Cambridge, Massachusetts); Muthusamy Jayaraman (Cambridge, Massachusetts); David Butler (Cambridge, Massachusetts); Jayaprakash K. Nair (Cambridge, Massachusetts); Martin Maier (Cambridge, Massachusetts); Laxman Eltepu (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure wherein R1 and R2 are each independently for each occurrence optionally substituted C10-C30 alkyl, optionally substituted C10-C30 alkenyl, optionally substituted C10-C30 alkynyl, optionally substituted C10-C30 acyl, or -linker-ligand; R3 is H, optionally substituted C1-C10 alkyl, optionally substituted C2-C10 alkenyl, optionally substituted C2-C10 alkynyl, alkylhetrocycle, alkylphosphate, alkylphosphorothioate, alkylphosphorodithioate, alkylphosphonates, alkylamines, hydroxyalkyls, ω-aminoalkyls, ω-(substituted)aminoalkyls, ω-phosphoalkyls, ω-thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40 K), optionally substituted mPEG (mw 120-40 K), heteroaryl, heterocycle, or linker-ligand; E is O, S, N(Q), C(O), N(Q)C(O), C(O)N(Q), (Q)N(CO)O, O(CO)N(Q), S(O), NS(O)2N(Q), S(O)2, N(Q)S(O)2, SS, O═N, aryl, heteroaryl, cyclic or heterocycle; and, Q is H, alkyl, ω-aminoalkyl, ω-(substituted)aminoalky, ω-phosphoalkyl or ω-thiophosphoalkyl. |
| FILED | Tuesday, February 24, 2015 |
| APPL NO | 14/629991 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 31/713 (20130101) A61K 39/00 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 47/28 (20130101) A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) Acyclic or Carbocyclic Compounds C07C 229/08 (20130101) C07C 229/30 (20130101) C07C 237/16 (20130101) C07C 251/38 (20130101) C07C 251/78 (20130101) C07C 271/12 (20130101) C07C 271/20 (20130101) C07C 323/25 (20130101) Heterocyclic Compounds C07D 203/10 (20130101) C07D 317/28 (20130101) C07D 319/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682151 | Tsien et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Roger Tsien (La Jolla, California); Todd Aguilera (San Diego, California); Emilia Olson (Seattle, Washington); Tao Jiang (San Diego, California); Quyen Nguyen (Del Mar, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Tsien (La Jolla, California); Todd Aguilera (San Diego, California); Emilia Olson (Seattle, Washington); Tao Jiang (San Diego, California); Quyen Nguyen (Del Mar, California) |
| ABSTRACT | Disclosed herein, in certain embodiments, is a selective transport molecule with increased in vivo circulation. In some embodiments, a selective transport molecule disclosed herein has the formula (A-X-B-C)-M, wherein C is a cargo moiety; A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and M is a macromolecular carrier. |
| FILED | Thursday, July 15, 2010 |
| APPL NO | 13/384591 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48207 (20130101) A61K 47/48215 (20130101) Original (OR) Class A61K 47/48238 (20130101) A61K 47/48815 (20130101) A61K 49/0032 (20130101) A61K 49/0056 (20130101) Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682157 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Southern Illinois University (Carbondale, Illinois) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (Carbondale, Illinois) |
| INVENTOR(S) | Yong Gao (Carbondale, Illinois); Boyd Goodson (Carbondale, Illinois) |
| ABSTRACT | Composition and method for surface-functionalized SPION-based agents. Such agents can provide highly pH-sensitive MRI contrast in tissue. |
| FILED | Tuesday, November 05, 2013 |
| APPL NO | 14/072637 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/186 (20130101) A61K 49/1857 (20130101) A61K 49/1872 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682170 | Malshe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ajay P. Malshe (Springdale, Arkansas); Wenping Jiang (Fayetteville, Arkansas) |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas); NanoMech, Inc. (Springdale, Arkansas) |
| INVENTOR(S) | Ajay P. Malshe (Springdale, Arkansas); Wenping Jiang (Fayetteville, Arkansas) |
| ABSTRACT | A high-strength coating for dental and orthopedic implants utilizing hydroxyapatite (HAp) nanoparticles provides for a high level of osseointegration through a range of surface pore sizes in the micro- to nanoscale. Zinc oxide (ZnO) nanoparticles may be incorporated with the HAp nanoparticles to form a composite coating material, with ZnO providing infection resistance due to its inherent antimicrobial properties. A textured surface, consisting of “islands” of roughly square coating structures measuring about 250 μm on a side, with spacing of 50-100 μm therebetween, may further promote the osseointegration and antimicrobial properties of the implant coating. |
| FILED | Friday, August 20, 2010 |
| APPL NO | 13/391357 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/32 (20130101) A61L 27/56 (20130101) A61L 27/306 (20130101) Original (OR) Class A61L 2400/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24413 (20150115) Y10T 428/24893 (20150115) Y10T 428/24997 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682232 | Shore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Susan Shore (Ann Arbor, Michigan); David Martel (Ann Arbor, Michigan); Seth Koehler (Baltimore, Maryland) |
| ABSTRACT | Timed stimulation of both somatosensory system and auditory system is controlled, in such a manner, that an individual's brain activity is altered through spike-timing dependent plasticity, thereby reducing or removing tinnitus. |
| FILED | Monday, December 21, 2015 |
| APPL NO | 14/977416 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/128 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/02 (20130101) A61M 2021/0027 (20130101) A61M 2021/0072 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36 (20130101) Original (OR) Class A61N 1/361 (20130101) A61N 1/36032 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682919 | Day et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Billy W. Day (Pittsburgh, Pennsylvania); Waikok Michael Tsang (Pittsburgh, Pennsylvania); Vasiliy N. Korotchenko (Rockville, Maryland) |
| ABSTRACT | Compounds that stimulate fibroblast growth factor production, and thus cell growth are provided. Also provided are compositions comprising the compounds and methods of using the compounds. The compounds can be used to treat wounds, to expand cell populations, such as hematopoietic cells, or to grow tissue in vitro, among other uses. |
| FILED | Monday, August 22, 2016 |
| APPL NO | 15/243089 |
| ART UNIT | 1671 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) Acyclic or Carbocyclic Compounds C07C 211/42 (20130101) C07C 225/20 (20130101) Original (OR) Class Heterocyclic Compounds C07D 495/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682933 | Yan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | British Columbia Cancer Agency Branch (Vancouver, Canada); The University of British Columbia (Vancouver, Canada) |
| ASSIGNEE(S) | British Columbia Cancer Agency Branch (Vancouver, Canada); The University of British Columbia (Vancouver, Canada) |
| INVENTOR(S) | Luping Yan (Vancouver, Canada); Raymond J. Andersen (Vancouver, Canada); Marianne Dorothy Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Carmen Adriana Banuelos (Richmond, Canada) |
| ABSTRACT | Compounds having a structure of Structure I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R4, R6, Y1 and Y2 are as defined herein, and wherein at least one of R3 or R4 is a straight-chain C1-C6 haloalkyl, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided. |
| FILED | Friday, May 29, 2015 |
| APPL NO | 14/726129 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4015 (20130101) Heterocyclic Compounds C07D 207/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682948 | Ye |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Keqiang Ye (Lilburn, Georgia) |
| ABSTRACT | In certain embodiments, the disclosure relates to 7,8-dihydoxyflavone and 7,8-substituted flavone derivatives, such as those described by formula provided herein, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing diseases or conditions related to BDNF and TrkB activity, such as psychiatric disorders, depression, post-traumatic stress disorder, and autism spectrum disorders, stroke, Rett syndrome, Parkinson's disease, and Alzheimer's disease by administering effective amounts of pharmaceutical compositions comprising compounds disclosed herein to a subject in need thereof. In certain embodiments, it is contemplated that the 7,8-substituted flavone derivatives disclosed herein are prodrugs of 7,8-dihydoxyflavone and analogs. |
| FILED | Friday, November 01, 2013 |
| APPL NO | 14/437232 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/352 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 311/28 (20130101) C07D 311/30 (20130101) Original (OR) Class C07D 311/36 (20130101) C07D 311/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682950 | Silverman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); He Huang (Chicago, Illinois); Qing Jing (Morton Grove, Illinois) |
| ABSTRACT | Selective neuronal nitric oxide synthase (nNOS) inhibitor compounds designed with one or more thiophene-2-carboximidamide substituents for improved bioavailability. |
| FILED | Monday, January 25, 2016 |
| APPL NO | 15/005501 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 333/38 (20130101) Original (OR) Class C07D 409/12 (20130101) C07D 409/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682966 | Roberts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Edward Roberts (Fallbrook, California); Miguel A. Guerrero (San Diego, California); Mariangela Urbano (Del Mar, California); Hugh Rosen (La Jolla, California) |
| ABSTRACT | The invention provides novel ligands of Kappa (κ) opioid receptors, such as can be used to modulate a Kappa opioid receptor. Methods of synthesis and methods of use are also provided. Compounds of the invention can be used therapeutically in the treatment of dissociative disorders or pain, or to provide neuroprotection, or to induce diuresis, or to modulate the immune system, or for treatment of one or more of an affective disorders comprising depression or stress/anxiety; an addictive disorder; alcoholism, epilepsy; a cognition deficiency; schizophrenia; Alzheimer's disease; or pain. |
| FILED | Friday, August 16, 2013 |
| APPL NO | 14/421932 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 211/58 (20130101) C07D 401/04 (20130101) C07D 405/14 (20130101) Original (OR) Class C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682983 | Alimardanov et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Washington, District of Columbia) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Dept. of Health and Human Services, National Institutes of Health (Bethesda, Maryland) |
| INVENTOR(S) | Asaf Alimardanov (North Bethesda, Maryland); Gregory D. Cuny (Houston, Texas); Gurmit Singh Grewal (Lexington, Massachusetts); Arthur Lee (Gaithersburg, Maryland); John C. McKew (Boyds, Maryland); Agustin H. Mohedas (Somerville, Massachusetts); Min Shen (Boyds, Maryland); Xin Xu (Potomac, Maryland); Paul B. Yu (Boston, Massachusetts) |
| ABSTRACT | The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds may also be used to reduce circulating levels of ApoB-100 or LDL and treat or prevent acquired or congenital hypercholesterolemia or hyperlipoproteinemia; diseases, disorders, or syndromes associated with defects in lipid absorption or metabolism; or diseases, disorders, or syndromes caused by hyperlipidemia. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/776302 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682990 | Cushman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Mark Stanley Cushman (West Lafayette, Indiana); Daniel Edward Beck (Lafayette, Indiana) |
| ABSTRACT | The invention described herein pertains to substituted indenoisoquinoline compounds as described herein, wherein RA, RD, W, X and Y are defined herein, pharmaceutical compositions and formulations comprising the indenoisoquinoline compounds, their synthesis, and methods for their use in the treatment and/or prevention of cancer. |
| FILED | Monday, May 02, 2016 |
| APPL NO | 15/144311 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 491/056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682993 | Webb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Thomas R Webb (Menlo Park, California); Chandraiah Lagisetti (Collierville, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to compounds having anticancer activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with uncontrolled cellular proliferation using the compounds and compositions. This abstract is intended to be used as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Monday, December 09, 2013 |
| APPL NO | 14/650826 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/351 (20130101) Heterocyclic Compounds C07D 309/10 (20130101) C07D 493/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682994 | Valente et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Susana Valente (Stuart, Florida); Phil S. Baran (San Diego, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Susana Valente (Stuart, Florida); Phil S. Baran (San Diego, California) |
| ABSTRACT | Methods for preventing or treating retroviral infection, such as human immunodeficiency virus, in vivo utilize transcriptional inhibitory compounds. These include cortistatin A and analogs of the cortistatin family. |
| FILED | Tuesday, June 30, 2015 |
| APPL NO | 14/755426 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/4709 (20130101) A61K 31/4725 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 405/04 (20130101) C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683011 | Wnek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Gary E. Wnek (Cleveland, Ohio); Linghui Meng (Cleveland, Ohio) |
| ABSTRACT | A method of forming a cross-linked protein structures includes preparing a solution of protein dissolved in a benign solvent and forming an intermediate protein structure from the solution. The intermediate protein structure can be cross-linked by providing for a specific ratio of chemical cross-linking agents to form the cross-linked protein structure. The solution can be prepared by adding a cross-linker of N-hydroxysuccinimide (NHS) and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC) at a ratio of two-to-one of NHS to EDC to alcohol. PBS buffer (20×) can be added to the solution until the volume ratio of PBS buffer (20×) to alcohol is about one-to-one. About 16 percent by weight of protein can be dissolved in the solution. The solution can be electrospun to form an intermediate protein structure. After a period of time, the protein structure can be cross-linked to form the cross-linked protein structure. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 14/720331 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/22 (20130101) Peptides C07K 1/36 (20130101) C07K 1/107 (20130101) C07K 1/1075 (20130101) Original (OR) Class C07K 14/78 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) D01F 4/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683017 | Wall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Jonathan S. Wall (Knoxville, Tennessee); Timothy E. Sparer (Knoxville, Tennessee); Stephen J. Kennel (Knoxville, Tennessee) |
| ABSTRACT | Disclosed are methods of treating and/or inhibiting a viral infection in a subject. The methods include administering a therapeutically effective amount of heparin-binding peptide. Also disclosed herein are methods for blocking viral binding to a cell. Further disclosed are anti-viral compositions for administration to a subject infected with a virus. Administration of the anti-viral composition inhibits viral infection of the subject. |
| FILED | Thursday, July 16, 2015 |
| APPL NO | 14/801717 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/001 (20130101) C07K 14/035 (20130101) C07K 14/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683020 | Compans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Richard W. Compans (Atlanta, Georgia); Baozhong Wang (Duluth, Georgia); Fu Shi Quan (Gyeonggi-do, South Korea) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Richard W. Compans (Atlanta, Georgia); Baozhong Wang (Duluth, Georgia); Fu Shi Quan (Gyeonggi-do, South Korea) |
| ABSTRACT | This disclosure relates to immunogenic compositions and methods of enhancing an immune response to an antigen. In certain embodiments, the disclosure relates to virus-like carries comprising a TLR5 agonist on the exterior without an antigen. |
| FILED | Tuesday, July 31, 2012 |
| APPL NO | 14/236618 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/64 (20130101) A61K 2039/5258 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/195 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/14043 (20130101) C12N 2760/16122 (20130101) C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/18523 (20130101) C12N 2760/18534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683025 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Qinghong Zhang (Englewood, Colorado); Rui Zhao (Englewood, Colorado); Xiao-Jing Wang (Greenwood Village, Colorado); Melanie Blevins (Denver, Colorado) |
| ABSTRACT | The invention provides a peptide construct comprising a cell penetrating peptide and an inhibitory peptide that interferes with the interaction between E1A and CtBP. The invention also provides related pharmaceutical composition comprising such a peptide construct. Also provided is a conjugate comprising such a peptide construct and a carrier molecule. The invention also provides related pharmaceutical compositions. Also provided are related methods of inhibiting cell proliferation in an individual and methods of treating cancer in by such pharmaceutical compositions. The present application also provides methods of treating an inflammatory disease and inhibiting inflammation in an individual comprising administering to the individual an effective amount of a therapeutic agent comprising an inhibitory peptide that interferes with the interaction between E1A and CtBP. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/775643 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4703 (20130101) Original (OR) Class C07K 2319/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683026 | Hunter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christopher A. Hunter (Swarthmore, Pennsylvania); Jason Scott Stumhofer (Plymouth Meeting, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSLYVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Christopher A. Hunter (Swarthmore, Pennsylvania); Jason Scott Stumhofer (Plymouth Meeting, Pennsylvania) |
| ABSTRACT | Compositions and methods relating to WSX-1 and p28 (IL-30) are provided. In particular, methods of treating inflammatory conditions in mammalian subjects using various WSX-1, p28, EBI3, and gp130 polypeptides and complexes or moieties that bind to or modulate activity of such complexes are described. Isolated or recombinant complexes including soluble WSX-1 or gp130 polypeptides, isolated or recombinant WSX-1 fusion proteins, and isolated or recombinant p28 fusion proteins are also described. |
| FILED | Wednesday, July 18, 2007 |
| APPL NO | 11/880121 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 35/15 (20130101) A61K 35/17 (20130101) A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/54 (20130101) Original (OR) Class C07K 14/7155 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6863 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683030 | Raguram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | S. Raguram (Hillsborough, New Jersey); Viswanathan Sasisekharan (Cambridge, Massachusetts); Venkataramanan Soundararajan (Cambridge, Massachusetts); Ram Sasisekharan (Cambridge, Massachusetts); Vidya Subramanian (Somerville, Massachusetts); Kannan Tharakaraman (Arlington, Massachusetts) |
| ABSTRACT | The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 13/829675 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683039 | Aifantis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iannis Aifantis (Brooklyn, New York); Camille Lobry (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Iannis Aifantis (Brooklyn, New York); Camille Lobry (New York, New York) |
| ABSTRACT | The present invention is directed to methods of treating and preventing acute myeloid leukemia and acute myeloid leukemia relapse disease in a subject that involve administering a Notch receptor agonist. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/212418 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/18 (20130101) A61K 38/19 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 16/18 (20130101) C07K 16/22 (20130101) C07K 16/24 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 2317/73 (20130101) C07K 2317/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683213 | Murphy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | William L. Murphy (Waunakee, Wisconsin); Matthew Brian Parlato (Madison, Wisconsin); James A Molenda (Madison, Wisconsin); Ngoc Nhi Le (Norcross, Georgia) |
| ABSTRACT | Hydrogel compositions and methods of using hydrogel compositions are disclosed. Advantageously, the hydrogel compositions offer the ability to promote cellular expansion and/or cellular differentiation of various cells. |
| FILED | Friday, April 10, 2015 |
| APPL NO | 14/684120 |
| ART UNIT | 1676 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) Original (OR) Class C12N 2533/20 (20130101) C12N 2533/30 (20130101) C12N 2537/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6452 (20130101) G01N 33/4833 (20130101) G01N 2610/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683215 | Melton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Douglas A. Melton (Lexington, Massachusetts); Qiao Zhou (Somerville, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Douglas A. Melton (Lexington, Massachusetts); Qiao Zhou (Somerville, Massachusetts) |
| ABSTRACT | The present invention provides methods of reprogramming cells, for example, directly reprogramming a somatic cell of a first cell type into a somatic cell of a second cell type, are described herein. In particular, the present invention generally relates to methods for reprogramming a cell of an endoderm origin to a cell having pancreatic β-cell characteristics. The present invention also relates to an isolated population comprising reprogrammed cells, compositions and their use in the treatment of diabetes mellitus. In particular, the present invention relates to reprogramming a cell of an endoderm origin to a cell having pancreatic β-cell characteristics by increasing the protein expression of at least one transcription factor selected from Pdx1, Ngn3 or MafA in the cell of endoderm origin to reprogram the cell of an endoderm cell to a cell which exhibits at least one or at least two characteristics of an endogenous pancreatic β-cell. |
| FILED | Monday, August 24, 2009 |
| APPL NO | 13/060123 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) Original (OR) Class C12N 2501/60 (20130101) C12N 2799/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683231 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hai Jiang (Shanghai, China PRC); Justin Pritchard (Boston, Massachusetts); Douglas A. Lauffenburger (Cambridge, Massachusetts); Michael Hemann (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Hai Jiang (Shanghai, China PRC); Justin Pritchard (Boston, Massachusetts); Douglas A. Lauffenburger (Cambridge, Massachusetts); Michael Hemann (Cambridge, Massachusetts) |
| ABSTRACT | The invention is directed to a method of characterizing a mechanism of action of an agent (e.g., a chemotherapeutic agent, a genotoxic agent). The method comprises contacting a plurality of populations of cells with an agent to be assessed, wherein each population of cells have one gene of interest targeted by a small hairpin RNA (shRNA) and wherein said gene of interest regulates cell death and a plurality of genes that regulate cell death are targeted in the plurality of populations of cells. A responsiveness of each population of cells to the agent is determined, thereby obtaining an shRNA signature of the agent, so as to identify one or more genes that mediate a response to the agent, thereby characterizing the mechanism of action of the agent. The invention is also directed an article of manufacture for characterizing a mechanism of action of a chemotherapeutic or genotoxic agent. |
| FILED | Friday, December 16, 2011 |
| APPL NO | 13/993930 |
| ART UNIT | 1674 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1079 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683244 | Weaver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Scott C. Weaver (Galveston, Texas); Farooq Nasar (Pearland, Texas); Rodion V. Gorchakov (Houston, Texas); Hilda Guzman (Galveston, Texas); Naomi Forrester (Galveston, Texas); Gustavo Palacios (New Market, Maryland); Ian W. Lipkin (New York, New York); Robert B. Tesh (Galveston, Texas) |
| ABSTRACT | Embodiments are directed compositions related to Eilat virus and uses thereof. |
| FILED | Friday, June 21, 2013 |
| APPL NO | 13/923527 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2770/36121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683261 | Willey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
| ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | James C. Willey (Toledo, Ohio); Erin L. Crawford (Rossford, Ohio) |
| ABSTRACT | Described herein are compositions for evaluating nucleic acids, standardized mixture for assessing amounts of at least one target nucleic acid in a sample, and kits comprising the same. |
| FILED | Monday, March 16, 2015 |
| APPL NO | 14/659101 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6851 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2545/107 (20130101) C12Q 2545/107 (20130101) C12Q 2545/114 (20130101) C12Q 2545/114 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/166 (20130101) Electric Digital Data Processing G06F 19/20 (20130101) G06F 19/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683262 | Johnson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raymond M. Johnson (Indianapolis, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raymond M. Johnson (Indianapolis, Indiana) |
| ABSTRACT | Methods are provided for isolating CD8+ T cells. Furthermore, methods for purifying a subset of IL-13 expressing CD8 T cells are provided, such methods comprising the steps of marking the CD8+ T cells by labeling CD8, or selectively removing non-CD8 cells, and then purifying a subset of IL-13 expressing CD8+ T cells by marking a human biomarker such as C10orf128. Related antibodies and antiserums are also described, such antibodies related to a cell surface domain peptide for biomarker C10orf128, and human homologs of related mouse “activated” CD8IL-13 cell surface biomarkers Tm4sf19 and 1830127L07Rik. |
| FILED | Monday, March 09, 2015 |
| APPL NO | 14/642546 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/28 (20130101) C07K 2317/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0087 (20130101) C12N 5/0638 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) G01N 2333/295 (20130101) G01N 2333/5437 (20130101) G01N 2333/70517 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683263 | Henderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the secretary, DEPARTMENT OF HEALTH and HUMAN SERVICES (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Wendy A. Henderson (Bethesda, Maryland); Ralph M. Peace (Durham, North Carolina); Nicolaas H. Fourie (Washington, District of Columbia); Sarah K. Abey (Bethesda, Maryland) |
| ABSTRACT | Methods are disclosed herein for identifying a subject with irritable bowel syndrome (IBS). Methods are also disclosed for determining if an agent is effective for the treatment or prevention of IBS. Methods of treating a subject with IBS, such as a subject identified using the disclosed methods, are also provided. |
| FILED | Monday, May 19, 2014 |
| APPL NO | 14/892999 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/113 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683265 | Chiorazzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Feinstein Institute For Medical Research (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institute for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Nicholas Chiorazzi (Tenafly, New Jersey); Rajendra N. Damle (Hatfield, Pennsylvania); Tarun Wasil (Dix Hills, New York) |
| ABSTRACT | The subject invention discloses a method for determining the prognosis and probable clinical course of a subject diagnosed with B-CLL. Specifically, the invention involves comparing CD38 expression in a biological sample from the subject containing B-CLL cells to a baseline level of CD38 expression, wherein an elevated level of CD38 expression in relation to the baseline level of CD38 expression may indicate poor prognosis or aggressive course of disease in the subject. Also disclosed is a method for determining whether the Ig V genes of the B-CLL cells of a B-CLL patient are mutated, comprising comparing CD38 expression in a biological sample from the subject containing B-CLL cells to a baseline level of CD38 expression, wherein a lower level of CD38 expression in relation to the baseline level indicates IG V gene mutation. |
| FILED | Wednesday, June 29, 2016 |
| APPL NO | 15/196550 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1456 (20130101) G01N 33/57426 (20130101) G01N 2015/149 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683268 | Barouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts); WASHINGTON UNIVERSITY (St. Louis, Michigan) |
| ASSIGNEE(S) | Beth Israel Deaconess (Boston, Massachusetts); Washington University (Saint Louis, Missouri) |
| INVENTOR(S) | Dan Barouch (Newton, Massachusetts); Herbert W Virgin (Saint Louis, Missouri); David Wang (Saint Louis, Missouri); Guoyan Zhao (Saint Louis, Missouri); Larissa Thackray (Columbia, Illinois); Scott Handley (Saint Louis, Missouri); Rachel Presti (University City, Missouri) |
| ABSTRACT | The present invention relates to previously undescribed viruses that are associated with significant expansion of the virome, immunodeficiency, and enteropathy during lentiviral infection. The invention also provides methods to detect acquired immune deficiency syndrome (AIDS) or AIDS progression in a subject, methods to diagnose immunodeficiency or enteropathy in a subject, and methods to identify a therapeutic agent to treat the same. |
| FILED | Thursday, September 19, 2013 |
| APPL NO | 14/429559 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10321 (20130101) C12N 2710/20021 (20130101) C12N 2710/22021 (20130101) C12N 2720/00021 (20130101) C12N 2750/14021 (20130101) C12N 2750/14121 (20130101) C12N 2770/16021 (20130101) C12N 2770/32021 (20130101) C12N 2770/32321 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683269 | Gottwein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hvidovre Hospital (Hvidovre, Denmark); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Hvidovre Hospital (Hvidovre, Denmark); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Judith M. Gottwein (Frederiksberg, Denmark); Troels Kasper Hoyer Scheel (Copenhagen, Denmark); Robert Purcell (Bethesda, Maryland); Jens Bukh (Praestø, Denmark) |
| ABSTRACT | The present invention relates to molecular approaches to the production of nucleic acid sequences, which comprises the genome of infectious hepatitis C virus. In particular, the invention provides nucleic acid sequences which comprise the genomes of infectious hepatitis C viruses of either genotype 3a (strain S52) or genotype 4a (strain ED43). The invention therefore relates to the use of the nucleic acid sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and in the development of screening assays for the identification of antiviral agents for HCV. The invention therefore also relates to the use of viral particles derived from laboratory animals infected with S52 and ED43 viruses. |
| FILED | Tuesday, October 14, 2014 |
| APPL NO | 14/514023 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2770/24221 (20130101) C12N 2770/24243 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/707 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683921 | Halden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolf U. Halden (Phoenix, Arizona); Isaac B. Roll (Tempe, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Rolf U. Halden (Phoenix, Arizona); Isaac B. Roll (Tempe, Arizona) |
| ABSTRACT | Contaminant mass collection in saturated sedimentary environments for bioavailability determination. A casing includes a screen between the environment that is subject to sampling, such as a saturated sediment and the device itself. The casing includes a water intake zone, a pump, and sorptive media. The water intake zone, the pump, the screen and the sorptive media, are all operably linked in sequence. The screened casing is secured to form an in situ device; the screen is in fluid communication with the water intake zone and excludes endemic sediments and aquatic life. The in situ device is deployed in the saturated sedimentary environment. The pump operates to concentrate analytes from the selected environment in the sorptive media, where the concentrated analytes include the analyte mass of time-weighted fluid samples. |
| FILED | Tuesday, April 17, 2012 |
| APPL NO | 14/112711 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/08 (20130101) B01D 15/14 (20130101) B01D 24/40 (20130101) B01D 35/26 (20130101) B01D 36/02 (20130101) B01D 61/58 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/444 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) G01N 1/16 (20130101) G01N 1/18 (20130101) G01N 1/405 (20130101) G01N 5/02 (20130101) G01N 15/0631 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683965 | Clemmer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | David E. Clemmer (Bloomington, Indiana); Michael A. Ewing (Bloomington, Indiana) |
| ABSTRACT | A hybrid ion mobility spectrometer includes a single-pass drift tube having an ion inlet at one end and an ion outlet at an opposite end, a multiple-pass drift tube having an ion inlet and an ion outlet each coupled to the single pass drift tube between the ion inlet and the ion outlet thereof, and a set of ion gates each controllable between an open position to pass ions therethrough and a closed position to block ions from passing therethrough. The set of ion gates may be controlled to pass at least some ions traveling through the single-pass drift tube into the multiple-pass drift tube via the ion inlet of the multiple-pass drift tube and to pass at least some ions traveling through the multiple-pass drift tube into the single-pass drift tube via the ion outlet of the multiple-pass drift tube. |
| FILED | Tuesday, September 23, 2014 |
| APPL NO | 15/023575 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683990 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yin Xu (Philadelphia, Pennsylvania); Qin Yu (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Yin Xu (Philadelphia, Pennsylvania); Qin Yu (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to Angiopoietin-3 (Ang-3) and Angiopoietin-4 (Ang-4). The present invention also relates to methods of modulating an activity of Ang-3 or Ang-4. The present invention further relates to methods of treating cancer, diabetes, and arthritis. |
| FILED | Monday, July 30, 2012 |
| APPL NO | 13/562213 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1891 (20130101) A61K 48/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/574 (20130101) G01N 33/5064 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2333/515 (20130101) G01N 2800/042 (20130101) G01N 2800/102 (20130101) G01N 2800/323 (20130101) G01N 2800/325 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683993 | Linder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); OPKO Diagnostics, LLC (Woburn, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); OPKO Diagnostics, LLC (Woburn, Massachusetts) |
| INVENTOR(S) | Vincent Linder (Tewksbury, Massachusetts); Samuel K. Sia (New York, New York); George M. Whitesides (Newton, Massachusetts); Max Narovlyansky (Cambridge, Massachusetts); Adam Carlyn Siegel (New York, New York) |
| ABSTRACT | The present invention relates generally to microfluidic structures, and more specifically, to microfluidic structures and methods including meandering and wide channels. Microfluidic systems can provide an advantageous environment for performing various reactions and analyses due to a reduction in sample and reagent quantities that are required, a reduction in the size of the operating system, and a decrease in reaction time compared to conventional systems. Unfortunately, the small size of microfluidic channels can sometimes result in difficulty in detecting a species without magnifying optics (such as a microscope or a photomultiplier). A series of tightly packed microchannels, i.e., a meandering region, or a wide channel having a dimension on the order of millimeters, can serve as a solution to this problem by creating a wide measurement area. Although this invention mainly describes the use of meandering and wide channels in heterogeneous immunoassays on a microfluidic chip, this invention could be used for amplifying optical signals for other types of reactions and/or assays. |
| FILED | Wednesday, April 10, 2013 |
| APPL NO | 13/860160 |
| ART UNIT | 1677 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 2300/0636 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0883 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/82 (20130101) G01N 33/54366 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683996 | Parsa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew T. Parsa (San Francisco, California); Lewis L. Lanier (San Francisco, California); Courtney Crane (San Francisco, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andrew T. Parsa (San Francisco, California); Lewis L. Lanier (San Francisco, California); Courtney Crane (San Francisco, California) |
| ABSTRACT | The present disclosure is directed toward measurement of expression of one or both of an activating Natural Killer (NK) cell receptor and its ligand(s) on peripheral blood cells as a means to assess solid tumor burden. In particular, the present disclosure provides tools for assessing cancer recurrence or risk thereof following reduction of a solid tumor, and for developing a treatment regime for a cancer patient. |
| FILED | Friday, October 22, 2010 |
| APPL NO | 13/503009 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 33/57415 (20130101) G01N 33/57434 (20130101) G01N 33/57438 (20130101) G01N 33/57492 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683999 | Moller |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David R. Moller (Ellicott, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David R. Moller (Ellicott, Maryland) |
| ABSTRACT | Sarcoidosis is a multisystem disease characterized by granulomatous inflammation in affected organs. We have developed a blood test using mycobacterial catalase-peroxidase that has a high positive predictive value for confirming a diagnosis of sarcoidosis. |
| FILED | Friday, May 16, 2014 |
| APPL NO | 14/279591 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6866 (20130101) Original (OR) Class G01N 2333/57 (20130101) G01N 2800/24 (20130101) G01N 2800/7095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684008 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Edgar A. Brown (Decatur, Georgia); James D. Ross (Decatur, Georgia); Richard A. Blum (Atlanta, Georgia); Stephen P. Deweerth (Decatur, Georgia) |
| ABSTRACT | Disclosed are apparatus and methods that provide the ability to electrical stimulate a physical system, and actively eliminate interference with signal acquisition (artifacts) that arises from the stimulation. The technique implemented in the circuits and methods for eliminating interference connects a discharge path to a physical interface to the system to remove charge that is built-up during stimulation. By placing the discharge path in a feedback loop that includes a recording preamplifier and AC-coupling circuitry, the physical interface is brought back to its pre-stimulation offset voltage. The disclosed apparatus and methods may be used with piezoelectric transducers, ultrasound devices, optical diodes, and polarizable and non-polarizable electrodes. The disclosed apparatus can be employed in implantable devices, in vitro or in vivo setups with vertebrate and invertebrate neural tissue, muscle fibers, pancreatic islet cells, osteoblasts, osteoclasts, bacteria, algae, fungi, protists, and plants. |
| FILED | Thursday, December 19, 2013 |
| APPL NO | 14/133834 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04 (20130101) A61B 5/04001 (20130101) A61B 5/7217 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3704 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4836 (20130101) G01N 37/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684106 | Barbastathis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George Barbastathis (Boston, Massachusetts); Yuan Luo (Taipei, Taiwan); Raymond K. Kostuk (Tucson, Arizona); Jennifer K. Barton (Tucson, Arizona) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Arizona Board of Regents on Behalf of the University of Arizona (Scottsdale, Arizona) |
| INVENTOR(S) | George Barbastathis (Boston, Massachusetts); Yuan Luo (Taipei, Taiwan); Raymond K. Kostuk (Tucson, Arizona); Jennifer K. Barton (Tucson, Arizona) |
| ABSTRACT | A volume holographic imaging system, apparatus, and/or method enables the projection of a two-dimensional (2D) slice of a four-dimensional (4D) probing object. A 4D probing source object is illuminated to emit or scatter an optical field. A holographic element having one or more recorded holograms receives and diffracts the optical field into a diffracted plane beam having spectral information. A 4-f telecentric relay system includes a pupil filter on the relayed conjugate plane of the volume hologram and images the pupil of the volume hologram onto the front focal plane of the collector lens. A collector lens focuses the diffracted plane beam to a 2D slice of the 4D probing source object. The focused 2D slice is projected onto a 2D imaging plane. The holographic element may have multiple multiplexed holograms that are arranged to diffract light from the corresponding slice of the 4D probing source object. |
| FILED | Friday, October 08, 2010 |
| APPL NO | 13/500467 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/32 (20130101) Original (OR) Class Holographic Processes or Apparatus G03H 1/28 (20130101) G03H 1/041 (20130101) G03H 1/0248 (20130101) G03H 2001/0264 (20130101) G03H 2001/0268 (20130101) G03H 2210/45 (20130101) G03H 2223/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684127 | Qi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Minghao Qi (West Lafayette, Indiana); Li Fan (West Lafayette, Indiana); Jian Wang (West Lafayette, Indiana); Leo Tom Varghese (West Lafayette, Indiana) |
| ABSTRACT | An optical device includes a first optical cavity, a second optical cavity, a first light guide and a second light guide. Each of the first and second optical cavities is formed on a semiconductor substrate, and is configured to store light. The first light guide has an input, and is optically coupled to the first optical cavity by a first coupling strength. In addition, the first light guide is optically coupled to the second optical cavity by a second coupling strength. The second light guide has an output, and is coupled to the second optical cavity by a third coupling strength. The first coupling strength is greater than the second coupling strength, and the third coupling strength is greater than the second coupling strength. |
| FILED | Monday, October 15, 2012 |
| APPL NO | 14/382507 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) Original (OR) Class G02B 6/2746 (20130101) G02B 6/12007 (20130101) G02B 6/29343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684282 | Barbastathis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | George Barbastathis (Boston, Massachusetts); Yuan Luo (Taipei, Taiwan); Se Baek Oh (Millbrae, California) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | George Barbastathis (Boston, Massachusetts); Yuan Luo (Taipei, Taiwan); Se Baek Oh (Millbrae, California) |
| ABSTRACT | A volume holographic imaging system, apparatus, and/or method enables the projection of a two-dimensional (2D) slice of a four-dimensional (4D) probing object. A 4D probing source object is illuminated to emit or scatter an optical field. A holographic element having one or more recorded holograms receives and diffracts the optical field into a diffracted plane beam having spectral information. A 4-f telecentric relay system includes a pupil filter on the relayed conjugate plane of the volume hologram and images the pupil of the volume hologram onto the front focal plane of the collector lens. A collector lens focuses the diffracted plane beam to a 2D slice of the 4D probing source object. The focused 2D slice is projected onto a 2D imaging plane. The holographic element may have multiple multiplexed holograms that are arranged to diffract light from the corresponding slice of the 4D probing source object. |
| FILED | Friday, October 08, 2010 |
| APPL NO | 13/500464 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/32 (20130101) Holographic Processes or Apparatus G03H 1/28 (20130101) G03H 1/0248 (20130101) G03H 1/2286 (20130101) Original (OR) Class G03H 2001/0033 (20130101) G03H 2001/0072 (20130101) G03H 2001/266 (20130101) G03H 2001/2244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685174 | Karam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Zahi N. Karam (Ann Arbor, Michigan); Satinder Singh Baveja (Ann Arbor, Michigan); Melvin Mcinnis (Ann Arbor, Michigan); Emily Mower Provost (Ann Arbor, Michigan) |
| ABSTRACT | A system that monitors and assesses the moods of subjects with neurological disorders, like bipolar disorder, by analyzing normal conversational speech to identify speech data that is then analyzed through an automated speech data classifier. The classifier may be based on a vector, separator, hyperplane, decision boundary, or other set of rules to classify one or more mood states of a subject. The system classifier is used to assess current mood state, predicted instability, and/or a change in future mood state, in particular for subjects with bipolar disorder. |
| FILED | Friday, May 01, 2015 |
| APPL NO | 14/702215 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/4803 (20130101) A61B 5/6898 (20130101) A61B 5/7246 (20130101) A61B 5/7264 (20130101) A61B 5/7267 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/22 (20130101) G10L 17/26 (20130101) G10L 25/03 (20130101) G10L 25/27 (20130101) G10L 25/48 (20130101) G10L 25/66 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 09682151 | Tsien et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Roger Tsien (La Jolla, California); Todd Aguilera (San Diego, California); Emilia Olson (Seattle, Washington); Tao Jiang (San Diego, California); Quyen Nguyen (Del Mar, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Tsien (La Jolla, California); Todd Aguilera (San Diego, California); Emilia Olson (Seattle, Washington); Tao Jiang (San Diego, California); Quyen Nguyen (Del Mar, California) |
| ABSTRACT | Disclosed herein, in certain embodiments, is a selective transport molecule with increased in vivo circulation. In some embodiments, a selective transport molecule disclosed herein has the formula (A-X-B-C)-M, wherein C is a cargo moiety; A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and M is a macromolecular carrier. |
| FILED | Thursday, July 15, 2010 |
| APPL NO | 13/384591 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48207 (20130101) A61K 47/48215 (20130101) Original (OR) Class A61K 47/48238 (20130101) A61K 47/48815 (20130101) A61K 49/0032 (20130101) A61K 49/0056 (20130101) Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682168 | Joshi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Neel Satish Joshi (Somerville, Massachusetts); Daniel James Rubin (Cambridge, Massachusetts) |
| ABSTRACT | The disclosed subject matter can provide a nanotube-reinforced polymer composite material comprising a plurality of nanotubes, each nanotube being formed of a plurality of cyclic peptide molecules, disposed within a polymer matrix, such as a biodegradable polymer matrix. A cyclic polymer, such as a cyclic 8-mer, composed of amino acid residues of alternating absolute configurations (D/L, R/S), can self-assemble into nanotubes useful for preparation of the composite polymer material of the invention. For example, the cyclic peptide (QL)4, wherein the glutamine and leucine residues are of opposite absolute configuration, self-assembles into nanotubes, which when formed into a reinforced polymer composite including poly(caprolactone), provides a biocompatible material of greater tensile strength and Young's modulus compared to the poly(caprolactone) material alone. The nanotubes can be prepared by a vapor equilibration technique or by a solvent-nonsolvent precipitation technique. The materials of the invention can be used for implants, stents and the like as well as for synthetic ligaments, tendons, cartilage, and bone for use in the living tissue of a patient in need thereof. For example, a spinal fusion cage comprising a PDLLA polymer matrix with a plurality of nanotubes of the invention can exhibit enhanced stiffness. |
| FILED | Monday, November 26, 2012 |
| APPL NO | 14/360851 |
| ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0092 (20130101) A61K 47/42 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/26 (20130101) A61L 27/44 (20130101) A61L 27/44 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 31/125 (20130101) A61L 31/125 (20130101) A61L 31/129 (20130101) A61L 31/129 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) A61L 2430/10 (20130101) A61L 2430/34 (20130101) A61L 2430/38 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/22 (20130101) C08K 7/22 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 1/02 (20130101) C08L 5/04 (20130101) C08L 5/08 (20130101) C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 89/00 (20130101) C08L 101/16 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0053 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682217 | Franklin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Prytime Medical Devices, Inc (Boerne, Texas) |
| ASSIGNEE(S) | PRYTIME MEDICAL DEVICES, INC. (Boerne, Texas) |
| INVENTOR(S) | Curtis Franklin (Denver, Colorado); Jonathan L. Eliason (Ann Arbor, Michigan) |
| ABSTRACT | A vascular access system and method of use for said system. The vascular access system generally comprises a body member; a shuttle member movably coupled to the body member; and a plurality of access needles fixedly coupled to the shuttle member and extending from the body member to penetrate a patient's skin. |
| FILED | Wednesday, February 26, 2014 |
| APPL NO | 14/191236 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/158 (20130101) A61M 25/06 (20130101) Original (OR) Class A61M 25/065 (20130101) A61M 2005/1585 (20130101) A61M 2005/1586 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682773 | Kennedy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Seal Beach, California) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Dennis K. Kennedy (Mesa, Arizona); Zach Keely Stahlecker (Chandler, Arizona); Saul Opie (Mesa, Arizona) |
| ABSTRACT | Systems and methods for blade attachment are proved. The systems and methods include an aircraft system having a rotor hub including a blade connector and a composite blade including a lug fitting assembly. The lug fitting assembly includes a fitting core including a lug fitting aperture, a lug bushing coupled within the lug fitting aperture, and an outer fitting substantially surrounding the fitting core. |
| FILED | Tuesday, June 25, 2013 |
| APPL NO | 13/926295 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/48 (20130101) Original (OR) Class B64C 2027/4736 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) Y10T 403/7075 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682856 | Whitesides et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George Whitesides (Newton, Massachusetts); Xinyu Liu (Montreal, Canada); XiuJun Li (El Paso, Texas); Martin M. Thuo (Southborough, Massachusetts); Michael O'Brien (Whitefish, Montana); Yu Sun (Toronto, Canada) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George Whitesides (Newton, Massachusetts); Xinyu Liu (Montreal, Canada); XiuJun Li (El Paso, Texas); Martin M. Thuo (Southborough, Massachusetts); Michael O'Brien (Whitefish, Montana); Yu Sun (Toronto, Canada) |
| ABSTRACT | MEMS devices fabricated using inexpensive substrate materials such as paper or fabric, are provided. Using paper as a substrate, low cost, simple to prepare, lightweight, disposable piezoresistive sensors, including accelerometers are prepared. Signal-processing circuitry can also be patterned on the substrate material. The sensors can be utilized as two-dimensional sensors, or the paper substrate material can be folded to arrange the sensors in a three dimensional conformation. For example, three sensors can be patterned on a paper substrate and folded into a cube such that the three sensors are orthogonally positioned on the faces of a cube, permitting simultaneous measurement of accelerations along three orthogonal directions (x-y-z). These paper-based sensors can be mass produced by incorporating highly developed technologies for automatic paper cutting, folding, and screen-printing. Also provided are methods of modifying paper for use as a substrate material in MEMS devices. |
| FILED | Wednesday, July 25, 2012 |
| APPL NO | 13/557861 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/02 (20130101) Original (OR) Class Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/0015 (20130101) Weighing G01G 3/13 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) G01P 15/123 (20130101) G01P 15/0802 (20130101) G01P 2015/0862 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682895 | Patel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rajen B. Patel (Parsippany, New Jersey); Victor Stepanov (Highland Park, New Jersey); Ashok Surapaneni (Hackettstown, New Jersey); Anthony DiStasio (New York, New York) |
| ASSIGNEE(S) | The United State of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Rajen B. Patel (Parsippany, New Jersey); Victor Stepanov (Highland Park, New Jersey); Ashok Surapaneni (Hackettstown, New Jersey); Anthony DiStasio (New York, New York) |
| ABSTRACT | An effective, safe and economical method of manufacture of an insensitive high explosive molding powder usable as a booster HE. The method preferably involving the steps of adding a binder and a crystalline high explosive to water, grinding that suspension in a bead mill until the crystalline high explosive is nano-sized, and precipitating the binder and crystalline high explosive using a spray dryer. Alternatively, an aqueous suspension of the crystalline high explosive can be ground in the bead mill and the binder subsequently added, prior to spray drying. A fatty alcohol, water defoaming/dispersant/surfactant agent can be added to the dissolved binder/suspended crystalline high explosive, to aid in the manufacturability. |
| FILED | Tuesday, March 18, 2014 |
| APPL NO | 14/217964 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0008 (20130101) Original (OR) Class C06B 21/0066 (20130101) C06B 25/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682897 | Harvey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California); Heather A. Meylemans (Ridgecrest, California) |
| ABSTRACT | A method for the efficient synthesis of useful deoxygenated terpenoids from an abundant renewable source, using catalytic conversion of oxygenated terpenoids. Oxygenated terpenoids such as 1,4-cineole and 1,8-cineole are, for example, major components of turpentine and essential oils. These oxygenated terpenoids can also be produced from sugars via a biosynthetic approach. Catalytic deoxygenation of these substrates can be used to efficiently generate commercially important chemicals and high density fuels for turbine or diesel propulsion. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142871 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) Original (OR) Class C07C 13/21 (20130101) C07C 13/23 (20130101) C07C 2101/14 (20130101) C07C 2521/16 (20130101) C07C 2531/10 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 2290/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683024 | Angov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Evelina Angov (Bethesda, Maryland); Elke Bergmann-Leitner (Kensington, Maryland); Christian Ockenhouse (Chevy Chase, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| INVENTOR(S) | Evelina Angov (Bethesda, Maryland); Elke Bergmann-Leitner (Kensington, Maryland); Christian Ockenhouse (Chevy Chase, Maryland) |
| ABSTRACT | A synthetic nucleotide, which transcribes as the cell-traversal protein for ookinetes and sporozoites (CelTOS) antigen of Malaria Plasmodium, and methods of use thereof. |
| FILED | Monday, July 20, 2015 |
| APPL NO | 14/803583 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/015 (20130101) A61K 2039/57 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/445 (20130101) Original (OR) Class C07K 16/205 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56905 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683197 | Aizenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Joanna Aizenberg (Boston, Massachusetts); Benjamin Hatton (Toronto, Canada); Xi Yao (Cambridge, Massachusetts); Michael Aizenberg (Boston, Massachusetts); Wendong Wang (Somerville, Massachusetts) |
| ABSTRACT | The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces (SLIPS) that can be modified as desired. Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of objects, referred to herein as Object A (Solid A or Liquid A). Use of an external stimuli or degradation of the Liquid B can be utilized to change the characteristics of SLIPS structures reversibly or irreversibly that may be desired in a number of different applications. Numerous characteristics, such as adhesion, optical, mechanical, and the like, can be dynamically changed. |
| FILED | Friday, May 02, 2014 |
| APPL NO | 14/268171 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/28 (20130101) A61F 2240/001 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/50 (20130101) A61L 15/425 (20130101) A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 29/14 (20130101) A61L 29/146 (20130101) A61L 2400/10 (20130101) A61L 2400/16 (20130101) A61L 2400/18 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/00 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 3/06 (20130101) B05D 3/007 (20130101) B05D 3/12 (20130101) B05D 3/14 (20130101) B05D 3/207 (20130101) B05D 3/0254 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 171/001 (20130101) Original (OR) Class Pipe-line Systems; Pipe-lines F17D 1/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0324 (20150401) Y10T 428/139 (20150115) Y10T 428/24355 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683281 | Meehan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Robert J. Meehan (Manchester, Connecticut); Neil B. Ridgeway (South Windsor, Connecticut); Christopher J. Millea (Coventry, Connecticut) |
| ABSTRACT | A method of forming a thermal barrier coating on a metal part includes laser cleaning a surface of the metal part to remove undesirable oxides and residues from the surface of the part. It further includes depositing an aluminum containing bondcoat on the part and thermally interdiffusing the bondcoat and the part with a heat treatment. Laser cleaning a surface of the bondcoat to remove oxides and debris from the surface forms an alpha aluminum oxide layer on the bondcoat. A ceramic topcoat is then deposited on the alpha aluminum oxide layer at a temperature above 1800° F. (982° C.). |
| FILED | Friday, April 10, 2015 |
| APPL NO | 14/683820 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/40 (20130101) B23K 26/082 (20151001) B23K 26/122 (20130101) B23K 26/123 (20130101) B23K 2203/10 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/02 (20130101) Original (OR) Class C23C 4/18 (20130101) C23C 4/073 (20160101) C23C 4/134 (20160101) C23C 14/022 (20130101) C23C 14/30 (20130101) C23C 14/083 (20130101) C23C 14/325 (20130101) C23C 28/3215 (20130101) C23C 28/3455 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/13 (20130101) F05D 2230/31 (20130101) F05D 2300/701 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683283 | Shen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mo-How Herman Shen (Dublin, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mo-How Herman Shen (Dublin, Ohio) |
| ABSTRACT | A method to increase the damping of a substrate using a face-centered cubic ferromagnetic damping coating. |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/268748 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/043 (20130101) B32B 2255/06 (20130101) B32B 2603/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/16 (20130101) Original (OR) Class C23C 14/24 (20130101) C23C 14/0635 (20130101) C23C 14/5873 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 5/26 (20130101) Non-positive-displacement Pumps F04D 29/38 (20130101) F04D 29/324 (20130101) F04D 29/668 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/30 (20130101) F05D 2230/30 (20130101) F05D 2300/1723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683443 | Freeman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Ted J. Freeman (Danville, Indiana); Richard C. Uskert (Timonium, Maryland) |
| ABSTRACT | A method for making a gas turbine engine ceramic matrix composite airfoil is disclosed. The method includes fabricating an airfoil preform that has a slotted forward end and a continuous trailing end. The slotted forward end of the airfoil preform is coupled to an airfoil core insert. A ceramic matrix composite covering is applied to cover the slots of the airfoil perform. The continuous trailing end of the airfoil preform is removed to expose the slots. A gas turbine engine airfoil is also disclosed. |
| FILED | Thursday, December 26, 2013 |
| APPL NO | 14/141395 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/04 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/147 (20130101) F01D 5/186 (20130101) Original (OR) Class F01D 5/187 (20130101) F01D 5/282 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/10 (20130101) F05D 2230/50 (20130101) F05D 2240/122 (20130101) F05D 2240/304 (20130101) F05D 2300/6033 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49337 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683514 | Herr |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John David Herr (Bellefonte, Pennsylvania) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John David Herr (Bellefonte, Pennsylvania) |
| ABSTRACT | A powering system includes an engine having a first side and an interface for providing heat to the first side of the engine. The interface includes a combustor having a combustion chamber positioned at least partially in an enclosure that receives a fuel and an oxidizer for combustion of the fuel and oxidizer into a combustion product. A conduit is connected to the combustion chamber for receiving the combustion product. A heat transfer fluid is positioned in the enclosure and engages an external surface of the combustion chamber and an external surface of the conduit within the enclosure. The heat transfer fluid is heated by the combustion product via the external surface of the combustion chamber and the external surface of the conduit such that the heat transfer fluid transfers heat to the first side of the engine. The heat transfer fluid may thereby decouples the engine from the combustor. |
| FILED | Friday, March 16, 2012 |
| APPL NO | 14/006530 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for F02G 1/055 (20130101) F02G 1/057 (20130101) Original (OR) Class F02G 2254/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683803 | Dix et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stephen M. Dix (Fredericksburg, Virginia); Tracy V. White (Dunnsville, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stephen M. Dix (Fredericksburg, Virginia); Tracy V. White (Dunnsville, Virginia) |
| ABSTRACT | A tripod is provided for mounting a machine gun between a front pintle and a traverse-and-elevation (T&E) device, being mechanically alterable between stowage and deployment configurations by means of a curved traverse bar. The tripod includes a head member for receiving the front pintle, a fore leg, first and second rear legs, and the traverse bar. The fore leg connects to the head member at a fore pitch hinge, and extends in the deployment configuration and folds aft beneath the head member in the stowage configuration. The first and second rear legs connect to the head member by corresponding rear lateral hinges. Each rear leg has a rail member that slides longitudinally therealong. The rear legs splay outward from the head member in the deployment configuration and contract substantially parallel in the stowage configuration. The traverse bar includes an elongated member for mounting the T&E device, first and second terminals at opposite ends of the elongated member, and a sprocket. The elongated member has an arc curvature that enables the T&E device to travel along the elongated member with constant elevation of the machine gun. The terminals respectively attach to the first and second legs by respective orifices. The first terminal includes a circular serrated cavity to receive the sprocket that has the first pivot orifice being offset from its axial center. The sprocket is removable to rotate the first pivot orifice for subsequent reinsertion into the serrated cavity. |
| FILED | Wednesday, December 07, 2016 |
| APPL NO | 15/371272 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 23/12 (20130101) Original (OR) Class F41A 27/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683817 | Camp |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Thomas Camp (Colonial Beach, Virginia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James Thomas Camp (Colonial Beach, Virginia) |
| ABSTRACT | A magnetic coupling (MC) circuit is provided for detecting an obscured object. The MC circuit connects to a current measuring instrument and includes a Marx bank having a plurality of stages; a peaking circuit; and an induction loop. Each stage of the Marx bank includes a resistor-capacitor (RC) loop having a first resistor connecting to a breakdown circuit. The Marx bank connects to a fixed potential known as ground. The breakdown circuit includes a breakdown switch, a second resistor and a bank capacitor. The voltage source connects to the Marx bank. The peaking circuit includes a peaking inductor, a peaking capacitor and a peaking switch disposed in parallel. The peaking switch connects the Marx bank to the peaking capacitor. The induction loop includes an impedance inductor connecting to the peaking switch. The instrument measures a first current in absence of the object and a second current in presence of the object, and detects the object based on difference between the first and second currents. |
| FILED | Wednesday, May 20, 2015 |
| APPL NO | 14/718066 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/32 (20130101) F41H 11/136 (20130101) Original (OR) Class Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/101 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/06 (20130101) Pulse Technique H03K 3/53 (20130101) H03K 3/537 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683820 | Patel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Orbital Research Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Mehul Patel (Chandler, Arizona); T. Terry Ng (Sylvania, Ohio); Alan B. Cain (Chesterfield, Missouri); Zak Sowle (Centerville, Ohio); Jack DiCocco (Broadview Heights, Ohio) |
| ABSTRACT | The present invention relates to an aircraft, missile, projectile, or underwater vehicle with an improved control system and a method for increasing the maneuverability or stability of an aircraft, missile, projectile, or underwater vehicle. More particularly, the present invention relates to a method for increasing the maneuverability or stability of an aircraft, missile, underwater vehicle or projectile through the use of removable control surfaces. The technical advantage of the removable control surface system (or “removable control surface”) over other systems is that the removable control surface system enables the aircraft, missile, underwater vehicle or projectile to have two or more design configurations, each configuration being tailored to the aircraft, missile, projectile, or underwater vehicle's specific stability or maneuverability requirements during a specific portion of the flight. |
| FILED | Friday, January 04, 2013 |
| APPL NO | 13/734368 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Weapon Sights; Aiming F41G 7/20 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/02 (20130101) F42B 10/64 (20130101) Original (OR) Class F42B 15/01 (20130101) F42B 19/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09683846 — Resonator fiber optic gyroscope resonance detection demodulator reference phase corrector
| US 09683846 | Strandjord et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Lee K. Strandjord (Tonka Bay, Minnesota); Waymon Ho (Glendale, Arizona); Chuck Croker (Glendale, Arizona) |
| ABSTRACT | A RFOG, comprising: a master laser emitting a reference optical signal; first and second slave lasers emitting first and second optical signals; an optical resonator ring cavity coupled to the lasers, the first and second optical signals propagating in first and second directions through the optical resonator ring cavity; one or more signal generators to inject first and second modulation signals at first and second frequencies on both optical signals; first and second photodetectors that generate first and second signals; first and second demodulators to demodulate the first and second signals using first and second reference signals and the first and second frequencies; a differencing function to output the difference between resonance frequencies of the first and second signals; at least a third demodulator to detect reference phase errors; and at least one phase servo to adjust the phase of at least one of the first and second reference signals. |
| FILED | Monday, November 23, 2015 |
| APPL NO | 14/949552 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/721 (20130101) G01C 19/727 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684025 | Duncan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Adam Duncan (Bloomington, Indiana); Matthew Gadlage (Bloomington, Indiana) |
| ABSTRACT | A method and system for determining short, open, and good connections using digital input and output (IO) structures in a device under test (DUT) continuity test, through the combined methods of using resistance-capacitance (RC) delay, time domain reflectometry (TDR), and forcing voltage on to a single IO pin of the DUT while measuring voltage on remaining IO pins of said DUT. In one embodiment, the combined methods are executed without the DUT in a test socket to produce a first set of test values and also with the DUT in a test socket to produce a second set of test values. The first and second sets of test values are compared to determine if one or more circuits of the DUT have a short circuit, an open circuit, or are a good (have an electrical connection that is not a short circuit or an open circuit) circuit. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 14/554954 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/11 (20130101) G01R 31/024 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684127 | Qi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Minghao Qi (West Lafayette, Indiana); Li Fan (West Lafayette, Indiana); Jian Wang (West Lafayette, Indiana); Leo Tom Varghese (West Lafayette, Indiana) |
| ABSTRACT | An optical device includes a first optical cavity, a second optical cavity, a first light guide and a second light guide. Each of the first and second optical cavities is formed on a semiconductor substrate, and is configured to store light. The first light guide has an input, and is optically coupled to the first optical cavity by a first coupling strength. In addition, the first light guide is optically coupled to the second optical cavity by a second coupling strength. The second light guide has an output, and is coupled to the second optical cavity by a third coupling strength. The first coupling strength is greater than the second coupling strength, and the third coupling strength is greater than the second coupling strength. |
| FILED | Monday, October 15, 2012 |
| APPL NO | 14/382507 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) Original (OR) Class G02B 6/2746 (20130101) G02B 6/12007 (20130101) G02B 6/29343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684309 | Carter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | David W. Carter (Nahant, Massachusetts); Scott A. Rasmussen (Andover, Massachusetts) |
| ABSTRACT | A guidance, navigation and control (GNC) system guides an aircraft based on a special partial differential equation (PDE). The system does not depend on a predetermined desired flight path. To overcome effects of unpredictable wind speed and direction, systems and methods effectively repeatedly determine the worst landing the wind can cause and issue flight control commands that minimize among these worst outcomes. A function C that satisfies the PDE calculates smallest miss distance a guidance system can bring about by appropriately steering an aircraft, given the aircraft's current heading, current location relative to a target and current remaining amount of time to fly. The system repeatedly determines at least a component of a current gradient of the function C. A value of the gradient component is used to select an appropriate flight control command, such as turn left or turn right. |
| FILED | Wednesday, January 06, 2016 |
| APPL NO | 14/989033 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 23/00 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684865 | Ezick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | Significs and Elements, LLC (New York, New York) |
| INVENTOR(S) | James Ezick (Canonsburg, Pennsylvania); Jonathan Springer (Carbondale, Illinois); Nicolas T. Vasilache (New York, New York) |
| ABSTRACT | In a system for enabling configuration of an ensemble of several solvers, such that the ensemble can efficiently solve a constraint problem, for each one of several candidate configurations, an array of scores is computed. The array corresponds to a statistical parameter related to a problem solution, and the computation is based on, at least in part, a set of features associated with the problem. One candidate configuration is assigned to a solver, and based on the array of scores associated with that candidate configuration the same or a different candidate configuration is assigned to a another solver. A system for dynamically reconfiguring an ensemble of solvers obtains runtime data from several solvers, and a new configuration is determined by applying a machine learning and/or heuristic analysis procedure to the runtime data. The configuration of a solver may be updated according to the new configuration while that solver is running. |
| FILED | Wednesday, June 05, 2013 |
| APPL NO | 13/910467 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Original (OR) Class G06N 99/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685088 | Trent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARCHITECTURE TECHNOLOGY, INC. (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barry A. Trent (Chanhassen, Minnesota); Ranga S. Ramanujan (Medina, Minnesota); Fabio F. Pozzo (Minneapolis, Minnesota) |
| ABSTRACT | A communication travel plan generation system for a vehicle is provided. The vehicle includes a communication hub, a system input and at least one controller. The communication hub is housed in the vehicle and is configured to communicate with a plurality of spaced subscriber communication nodes. The system input is configured to receive mission-specific information. The at least one controller is in communication with the system input. Moreover, the at least one controller is configured to apply the mission-specific information to a mission planning system to generate a mission plan of the vehicle. The at least one controller is further configured to implement the communication travel plan generation system to automatically generate travel waypoints for the mission planning system based at least in part on the mission-specific information applied to the mission planning system. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/093826 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0022 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/047 (20130101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0026 (20130101) G08G 5/0034 (20130101) Original (OR) Class G08G 5/0043 (20130101) G08G 5/0086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685208 | Kulkarni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jaydeep P. Kulkarni (Portland, Oregon); Anupama Thaploo (Maricopa, Arizona); Iqbal Rajwani (Roseville, California); Kyung-Hoae Koo (Hillsboro, Oregon); Eric A. Karl (Portland, Oregon); Muhammad Khellah (Tigard, Oregon) |
| ABSTRACT | Embodiments include apparatuses, methods, and systems related to an assist circuit that may be coupled to one or more components of a memory system to selectively lower a supply voltage that is delivered to the component. For example, the assist circuit may be coupled to a plurality of bitcells (e.g., register file bitcells). The assist circuit may selectively lower the supply voltage delivered to the bitcells during at least a portion of a write operation and/or during an inactive state of the bitcells. Additionally, or alternatively, the assist circuit may be coupled to a read circuit to selectively lower the supply voltage delivered to the read circuit during an inactive state of the read circuit. The assist circuit may include a control transistor coupled in parallel with one or more diodes between a main supply rail and a supply node of the bitcells and/or read circuit. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/094755 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 7/12 (20130101) Original (OR) Class G11C 7/22 (20130101) G11C 7/1048 (20130101) G11C 7/1069 (20130101) G11C 11/419 (20130101) G11C 17/16 (20130101) G11C 2207/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685231 | Gadlage et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Gadlage (Bloomington, Indiana); Matthew Kay (Jasper, Indiana); James D. Ingalls (Bedford, Indiana); Adam Duncan (Bloomington, Indiana); Austin Roach (Bloomfield, Indiana) |
| ABSTRACT | An irreproducible and re-emergent unique structure or pattern identifier manufacturing and detection method, system, and apparatus is provided. A non-volatile floating gate charge storage device can include a block of floating gate transistors that can include a semiconductor region, a source region, a drain region, a floating gate region, a tunnel oxide region, an oxide-nitrite-oxide region, and a control gate region. A structure altering stress effect is applied to the block of transistors to create a passage region in a random number of floating gate regions of floating gate transistors which changes charge storage or electrical characteristics of random elements of the block of transistors. The passage region alters charges on a floating gate region to escape in a different manner than pre-alteration form causing the floating gate region to lose its charge. An apparatus for recording and detecting such differences in pre and post alteration can also be provided. |
| FILED | Monday, April 07, 2014 |
| APPL NO | 14/246173 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/0013 (20130101) G06K 19/077 (20130101) Static Stores G11C 16/06 (20130101) G11C 16/0408 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/28273 (20130101) H01L 27/11521 (20130101) H01L 29/7881 (20130101) H01L 29/42324 (20130101) H01L 29/66825 (20130101) H01L 29/66833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685296 | Hoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brad Winston Hoff (Albuquerque, New Mexico); David Michael French (Albuquerque, New Mexico); Donald A. Shiffler (Albuquerque, New Mexico); Susan L. Heidger (Albuquerque, New Mexico); Wilkin W. Tang (Albuquerque, New Mexico) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia) |
| INVENTOR(S) | Brad Winston Hoff (Albuquerque, New Mexico); David Michael French (Albuquerque, New Mexico); Donald A. Shiffler (Albuquerque, New Mexico); Susan L. Heidger (Albuquerque, New Mexico); Wilkin W. Tang (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus for modulating the density of an electron beam as it is emitted from a cathode, comprised of connecting a source of pulsed input power to the input end of a nonlinear transmission line and connecting the output end directly to the cathode of an electron beam diode by a direct electrical connection. |
| FILED | Thursday, June 26, 2014 |
| APPL NO | 14/316766 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 29/52 (20130101) Original (OR) Class H01J 2229/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685349 | Mathews et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Scott A. Mathews (Takoma Park, Maryland); Iyoel Beniam (Washington, District of Columbia); Alberto Piqué (Crofton, Maryland) |
| ABSTRACT | A method of forming and transferring shaped metallic interconnects, comprising providing a donor substrate comprising an array of metallic interconnects, using a laser system to prepare the metallic interconnects, forming shaped metallic interconnects, and transferring the shaped metallic interconnect to an electrical device. An electronic device made from the method of providing a donor ribbon, wherein the donor ribbon comprises an array of metal structures and a release layer on a donor substrate, providing a stencil to the metal structures on the donor substrate, applying a laser pulse through the donor substrate to the metal structures, and directing the metal structures to an electronic device. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/178930 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4828 (20130101) Original (OR) Class H01L 21/76885 (20130101) H01L 24/05 (20130101) H01L 24/43 (20130101) H01L 24/45 (20130101) H01L 24/48 (20130101) H01L 24/85 (20130101) H01L 2224/435 (20130101) H01L 2224/04042 (20130101) H01L 2224/4805 (20130101) H01L 2224/4814 (20130101) H01L 2224/8585 (20130101) H01L 2224/43001 (20130101) H01L 2224/45012 (20130101) H01L 2224/45014 (20130101) H01L 2224/48101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685513 | Kub et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Francis J. Kub (Arnold, Maryland); Travis J. Anderson (Alexandria, Virginia); Karl D. Hobart (Upper Marlboro, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Francis J. Kub (Arnold, Maryland); Travis J. Anderson (Alexandria, Virginia); Karl D. Hobart (Upper Marlboro, Maryland) |
| ABSTRACT | Semiconductor devices that include a semiconductor structure integrated with one or more diamond material layers. A first diamond material layer is formed on a bottom surface and optionally, the side surfaces of the semiconductor structure. In some embodiments, at least a portion of the semiconductor structure is embedded in the diamond. An electrical device can be formed on a top surface of the semiconductor structure. A second diamond material layer can be formed on the top surface of the semiconductor structure. The semiconductor structure can include a III-nitride material such as GaN, which can be embedded within a the first diamond material layer or encased by the first and/or second diamond material layer. |
| FILED | Wednesday, October 23, 2013 |
| APPL NO | 14/060916 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3732 (20130101) H01L 23/5329 (20130101) H01L 29/78 (20130101) H01L 29/205 (20130101) H01L 29/1602 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 29/7787 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685567 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Jinsong Huang (Lincoln, Nebraska); Fawen Guo (Lincoln, Nebraska) |
| ABSTRACT | A photodetector includes an anode that is transparent or partially transparent to light, a cathode and an active layer disposed between the anode and the cathode. The active layer includes a nanocomposite material that has a polymer blended with nanoparticles or organic electron trapping particles. The photodetector has a low dark current when not illuminated by light and has a high conductivity when illuminated by light, in which the light passes the anode and is absorbed by the active layer. |
| FILED | Friday, July 19, 2013 |
| APPL NO | 13/946975 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02 (20130101) Original (OR) Class H01L 51/0036 (20130101) H01L 51/0094 (20130101) H01L 51/426 (20130101) H01L 51/4273 (20130101) H01L 2251/303 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685676 | Ren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhiyong Ren (Superior, Colorado); Casey Forrestal (Wheat Ridge, Colorado); Pei Xu (Las Cruces, New Mexico) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Zhiyong Ren (Superior, Colorado); Casey Forrestal (Wheat Ridge, Colorado); Pei Xu (Las Cruces, New Mexico) |
| ABSTRACT | Bioelectrochemical systems (BES) having configurations with spiral wound structures and with frame-and-plate structures are provided. Systems may allow for production of an electrical current that is at least partially generated by microorganisms connected directly or indirectly to an electrode. A spiral wound or frame-and-plate type bioelectrochemical system that may be used for energy or chemical production, and/or desalination may include an anolyte influent point, a catholyte influent point, electrodes, ion selective membranes, mesh separators, gas collection devices, an exterior containment vessel, and one or more external electrical devices. |
| FILED | Friday, September 14, 2012 |
| APPL NO | 14/345104 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4691 (20130101) C02F 3/005 (20130101) C02F 3/1268 (20130101) C02F 2303/10 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) Original (OR) Class H01M 8/0247 (20130101) H01M 8/04082 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/527 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/15 (20150501) Y02W 10/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686228 | Hom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard V. Hom (Troy, Michigan); Eric M. Nelson (Durham, North Carolina); James C. North (Virginia Beach, Virginia) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Richard V. Hom (Troy, Michigan); Eric M. Nelson (Durham, North Carolina); James C. North (Virginia Beach, Virginia) |
| ABSTRACT | The invention is directed to just-in-time (JIT) retrieval of directory information to reduce network traffic and load on directory servers and/or data sources by requesting only the information that is currently needed from the directory server. In the invention, a request handler operating with the directory server provides this capability. Specifically, the request handler and directory server are configured to receive a request for directory information from a client and to determine a location corresponding to a set of current attribute values for responding to the request. The request handler retrieves the set of current attribute values from at least one of the following: the directory server and an external source. A set of current attributes is returned to the client from the directory server. The request handler propagates information in a JIT manner so that only the information that will be currently used by the client is propagated across the network. |
| FILED | Wednesday, September 29, 2010 |
| APPL NO | 12/893453 |
| ART UNIT | 2159 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30589 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/12084 (20130101) H04L 29/12132 (20130101) H04L 61/1523 (20130101) Original (OR) Class H04L 61/1552 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686233 | Paxton |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Napoleon C. Paxton (Woodbridge, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Napoleon C. Paxton (Woodbridge, Virginia) |
| ABSTRACT | A method is described for calculating a first hash of a packet application layer payload at an inside sensor before a boundary, and storing a first hash data record at a device that has direct access to the inside sensor. A second hash of the packet application layer payload can be calculated at an outside sensor after the boundary, and a second hash data record can be stored at a device that has direct access to the outside sensor. The packet can be transmitted from a client to a server, or from a server to a client, and the boundary is between the client and the server. The first hash data record and second hash data record can include a hash value, an IP address, and a timestamp. Finally, a determination can be made whether the first hash data record and the second hash data record match. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/208314 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/04 (20130101) H04L 43/028 (20130101) H04L 61/2514 (20130101) H04L 61/2585 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686305 | Stirtzinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Securboration, Inc. (Melbourne, Florida) |
| ASSIGNEE(S) | Securboration, Inc. (Melbourne, Florida) |
| INVENTOR(S) | Anthony Stirtzinger (Ponte Vedra Beach, Florida); Keith Shapiro (Saint Louis, Missouri); Brian Warhover (Fairview Heights, Illinois); Bruce McQueary (Indialantic, Florida) |
| ABSTRACT | Systems, methods, and apparatus for identifying anomalous behavior are provided. For example, a method may include receiving raw data, generating a behavior profile for the entity based on the raw data, receiving comparison data, determining whether the comparison data deviates from a pattern of behavior defined in the behavior profile, and identifying the comparison data as anomalous behavior when the comparison data deviates from the pattern of behavior. In one embodiment, the raw data includes recorded activity for the entity. In one embodiment, the behavior profile defines a pattern of behavior for the entity. In one embodiment, a countermeasure is performed upon identifying anomalous behavior. The countermeasure may include at least one of revoking the entity's credentials, denying the entity access to a resource, shutting down access to a port, and denying access to the entity. The method may further include providing a report of the anomalous behavior. |
| FILED | Wednesday, November 20, 2013 |
| APPL NO | 14/085493 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1408 (20130101) H04L 63/1441 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686479 | Marks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Daniel Marks (Durham, North Carolina); David Jones Brady (Durham, North Carolina) |
| ABSTRACT | Methods for stitching multiple sub-images together to form a substantially seamless composite image are disclosed. Overlap regions formed by each pair of neighboring sub-images are periodically examined and key features common to the overlap regions in each sub-image of the pair are identified. A transformation is determined for each sub-image pair based on the positions of these key features. The transformation is split between the sub-images and applied to distort the overlap regions in each sub-image pair such that they are substantially aligned. Applying the transformations to each overlap region in the overall image enables creation of a substantially seamless composite image. In some embodiments, the process wherein the transformations are determined is run as a feedback loop to enable continuing refinement of the transformations. |
| FILED | Tuesday, September 16, 2014 |
| APPL NO | 15/022439 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 5/002 (20130101) Pictorial Communication, e.g Television H04N 5/247 (20130101) H04N 5/265 (20130101) Original (OR) Class H04N 5/23238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686789 | Gormley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EDEN ROCK COMMUNICATIONS, LLC (Bothell, Washington) |
| ASSIGNEE(S) | SPECTRUM EFFECT, INC. (Seattle, Washington) |
| INVENTOR(S) | Eamonn Gormley (Bothell, Washington); Jungnam Yun (Bothell, Washington); Rekha Menon (Bothell, Washington) |
| ABSTRACT | A method for coexistence with a pulsed interference source in a communications network includes receiving a communications signal, determining a first portion of the communications signal that is affected by the pulsed interference source, blanking the first portion of the communications signal, and processing the communications signal. |
| FILED | Friday, August 01, 2014 |
| APPL NO | 14/449918 |
| ART UNIT | 2411 — Multiplex and VoIP |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/2813 (20130101) G01S 7/2928 (20130101) G01S 13/5244 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 5/0078 (20130101) H04L 43/16 (20130101) Wireless Communication Networks H04W 16/14 (20130101) H04W 24/02 (20130101) H04W 72/0446 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 09681846 | Derzon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Mark S. Derzon (Albuquerque, New Mexico); Alex Robinson (Albuquerque, New Mexico); Paul C. Galambos (Albuquerque, New Mexico) |
| ABSTRACT | A radiation generator useful for medical applications, among others, is provided. The radiation generator includes a catheter; a plasma discharge chamber situated within a terminal portion of the catheter, a cathode and an anode positioned within the plasma discharge chamber and separated by a gap, and a high-voltage transmission line extensive through the interior of the catheter and terminating on the cathode and anode so as to deliver, in operation, one or more voltage pulses across the gap. |
| FILED | Tuesday, December 10, 2013 |
| APPL NO | 14/102422 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/4057 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1014 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 35/02 (20130101) X-ray Technique H05G 2/003 (20130101) H05G 2/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682531 | Seals et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Reston, Virginia) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Roland D. Seals (Oak Ridge, Tennessee); Edward B. Ripley (Knoxville, Tennessee); Russell L. Hallman (Knoxville, Tennessee) |
| ABSTRACT | Composite structures having a reinforced material interjoined with a substrate, wherein the reinforced material comprises a compound selected from the group consisting of titanium monoboride, titanium diboride, and combinations thereof. |
| FILED | Tuesday, February 18, 2014 |
| APPL NO | 14/182327 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 35/34 (20130101) B23K 35/325 (20130101) B23K 35/327 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/045 (20130101) Original (OR) Class B32B 15/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 12/02 (20130101) C23C 18/08 (20130101) C23C 18/1204 (20130101) C23C 18/1241 (20130101) C23C 18/1275 (20130101) C23C 26/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24802 (20150115) Y10T 428/24826 (20150115) Y10T 428/31678 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682859 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Reston, Virginia) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Sam W. Brown (Knoxville, Tennessee); Larry S. Spencer (Knoxville, Tennessee); Michael R. Phillips (Harriman, Tennessee); G. Louis Powell (Oak Ridge, Tennessee); Peggy J. Campbell (Clinton, Tennessee) |
| ABSTRACT | A method is provided for extracting hydrogen from lithium hydride. The method includes (a) heating lithium hydride to form liquid-phase lithium hydride; (b) extracting hydrogen from the liquid-phase lithium hydride, leaving residual liquid-phase lithium metal; (c) hydriding the residual liquid-phase lithium metal to form refined lithium hydride; and repeating steps (a) and (b) on the refined lithium hydride. |
| FILED | Tuesday, February 04, 2014 |
| APPL NO | 14/171801 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/22 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/04 (20130101) Original (OR) Class Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/00 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 26/12 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/364 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683225 | Spodsberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novozymes Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California); Novozymes A/S (Bagsvaerd, Denmark) |
| INVENTOR(S) | Nikolaj Spodsberg (Bagsvaerd, Denmark); Tarana Shaghasi (Dixon, California) |
| ABSTRACT | The present invention relates to polypeptides having xylanase activity, catalytic domains, and carbohydrate binding domains, and polynucleotides encoding the polypeptides, catalytic domains, and carbohydrate binding domains. The present invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, and carbohydrate binding domains. |
| FILED | Tuesday, December 18, 2012 |
| APPL NO | 14/353136 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2482 (20130101) Original (OR) Class C12N 15/8257 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 21/02 (20130101) C12P 2203/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683248 | Adney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | William S. Adney (Pittsboro, North Carolina); Gregg T. Beckham (Golden, Colorado); Eric Jarvis (Boulder, Colorado); Michael E. Himmel (Littleton, Colorado); Stephen R. Decker (Berthoud, Colorado); Jeffrey G. Linger (Denver, Colorado); Kara Podkaminer (Boulder, Colorado); John O. Baker (Golden, Colorado); Larry Taylor, II (Berthod, Colorado); Qi Xu (Lakewood, Colorado); Arjun Singh (Lakewood, Colorado) |
| ABSTRACT | Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in hosts such as fungi, which in turn may be cultured to produce chimeric polypeptides. Also disclosed are chimeric polypeptides and their use in the degradation of cellulosic materials. |
| FILED | Monday, December 17, 2012 |
| APPL NO | 14/365200 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/14 (20130101) C12P 19/02 (20130101) Original (OR) Class C12P 19/14 (20130101) Enzymes C12Y 302/01004 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683279 | Muralidharan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Govindarajan Muralidharan (Knoxville, Tennessee); Dane Francis Wilson (Oak Ridge, Tennessee); David Eugene Holcomb (Oak Ridge, Tennessee) |
| ABSTRACT | An alloy is composed essentially of, in terms of weight percent: 6 to 8.5 Cr, 5.5 to 13.5 Mo, 0.4 to 7.5 W, 1 to 2 Ti, 0.7 to 0.85 Mn, 0.05 to 0.3 Al, 0.08 to 0.5 C, 0 to 1 Nb, with the balance Ni, the alloy being characterized by, at 850° C., a yield strength of at least 25 Ksi, a tensile strength of at least 30 Ksi, a creep rupture life at 12 Ksi of at least 45 hours, and a corrosion rate, expressed in weight loss [g/(cm2 sec)]10−11 during a 1000 hour immersion in liquid FLiNaK at 850° C., in the range of 6 to 39. |
| FILED | Thursday, May 15, 2014 |
| APPL NO | 14/277992 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 19/05 (20130101) Original (OR) Class C22C 19/057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683280 | Muralidharan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Govindarajan Muralidharan (Knoxville, Tennessee); Dane Francis Wilson (Oak Ridge, Tennessee); David Eugene Holcomb (Oak Ridge, Tennessee) |
| ABSTRACT | An alloy consists essentially of, in terms of weight percent: 6 to 8.5 Cr, 5.5 to 13.5 Mo, 0.4 to 7.5 W, 1 to 2 Ti, 0.7 to 0.85 Mn, 0.05 to 0.3 Al, up to to 0.1 Co, 0.08 to 0.5 C, 1 to 5 Ta, 1 to 4 Nab, 1 to 3 Hf, balance Ni. The alloy is characterized by, at 850° C., a yield strength of at least 36 Ksi, a tensile strength of at least 40 Ksi, a creep rupture life at 12 Ksi of at least 72.1 hours, and a corrosion rate, expressed in weight loss [g/(cm2sec)]×10−11 during a 1000 hour immersion in liquid FLiNaK at 850° C., in the range of 8 to 25. |
| FILED | Friday, January 10, 2014 |
| APPL NO | 14/152215 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 19/057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683285 | Anders et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andre Anders (El Cerrito, California); Jonathan Kolbeck (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andre Anders (El Cerrito, California); Jonathan Kolbeck (Berkeley, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to blocking macroparticles in deposition processes utilizing plasmas. In one aspect, an apparatus includes a cathode, a substrate holder, a first magnet, a second magnet, and a structure. The cathode is configured to generate a plasma. The substrate holder is configured to hold a substrate. The first magnet is disposed proximate a first side of the cathode. The second magnet is disposed proximate a second side of the substrate holder. A magnetic field exists between the first magnet and the second magnet and a flow of the plasma substantially follows the magnetic field. The structure is disposed between the second side of the cathode and the first side of the substrate holder and is positioned proximate a region where the magnetic field between the first magnet and the second magnet is weak. |
| FILED | Tuesday, March 18, 2014 |
| APPL NO | 14/218434 |
| ART UNIT | 1754 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/35 (20130101) C23C 14/564 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/3405 (20130101) H01J 37/3408 (20130101) H01J 37/3447 (20130101) H01J 2237/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683309 | Swatloski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| ASSIGNEE(S) | Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| INVENTOR(S) | Richard P. Swatloski (Tuscaloosa, Alabama); Patrick S. Barber (Tuscaloosa, Alabama); Terrance Opichka (Tuscaloosa, Alabama); Jonathan R. Bonner (Brookwood, Alabama); Gabriela Gurau (Tuscaloosa, Alabama); Christopher Scott Griggs (Vicksburg, Mississippi); Robin D. Rogers (Tuscaloosa, Alabama) |
| ABSTRACT | Disclosed are methods for electrospinning chitinous biomass solution to form chitin fibers, using ionic liquids or other ion-containing liquids as solvent. Chitin fibers produced thereby and articles containing such chitin fibers are also disclosed. The chitin fiber thus obtained has very high surface area and improved strength over currently commercially available chitin materials. |
| FILED | Wednesday, July 24, 2013 |
| APPL NO | 13/949501 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 5/08 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Original (OR) Class D01D 5/0046 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683515 | Ernst et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cummins, Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | CUMMINS, INC. (Columbus, Indiana) |
| INVENTOR(S) | Timothy C. Ernst (Columbus, Indiana); James A. Zigan (Versailles, Indiana) |
| ABSTRACT | The disclosure describes a non-condensable gas collection, detection, and removal system for a WHR system that helps to maintain cycle efficiency of the WHR system across the life of an engine system associated with the WHR system. A storage volume is configured to collect non-condensable gas received from the working fluid circuit, and a release valve is configured to selectively release non-condensable gas contained within the storage volume. |
| FILED | Wednesday, July 02, 2014 |
| APPL NO | 14/322308 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 23/065 (20130101) Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for F02G 5/02 (20130101) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 21/0014 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683704 | Tamburello et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC. (Aiken, South Carolina) |
| INVENTOR(S) | David A. Tamburello (Aiken, South Carolina); Donald L. Anton (Aiken, South Carolina); Bruce J. Hardy (Graniteville, South Carolina); Claudio Corgnale (Aiken, South Carolina) |
| ABSTRACT | In one aspect, a system for controlling the temperature within a gas adsorbent storage vessel of a vehicle may include an air conditioning system forming a continuous flow loop of heat exchange fluid that is cycled between a heated flow and a cooled flow. The system may also include at least one fluid by-pass line extending at least partially within the gas adsorbent storage vessel. The fluid by-pass line(s) may be configured to receive a by-pass flow including at least a portion of the heated flow or the cooled flow of the heat exchange fluid at one or more input locations and expel the by-pass flow back into the continuous flow loop at one or more output locations, wherein the by-pass flow is directed through the gas adsorbent storage vessel via the by-pass line(s) so as to adjust an internal temperature within the gas adsorbent storage vessel. |
| FILED | Tuesday, November 18, 2014 |
| APPL NO | 14/546107 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/14 (20130101) B60H 1/00271 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 43/12 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 21/06 (20130101) F02M 21/0221 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 11/00 (20130101) F17C 11/007 (20130101) F17C 13/005 (20130101) Original (OR) Class F17C 2227/0395 (20130101) F17C 2250/0631 (20130101) F17C 2270/0168 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 5/02 (20130101) F25B 6/02 (20130101) F25B 41/04 (20130101) F25B 2400/0403 (20130101) F25B 2400/0409 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683976 | Mann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho) |
| ASSIGNEE(S) | BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho) |
| INVENTOR(S) | Nicholas R Mann (Idaho Falls, Idaho); Matthew G Watrous (Idaho Falls, Idaho); Christopher P Oertel (Idaho Falls, Idaho); Christopher A McGrath (Blackfoot, Idaho) |
| ABSTRACT | Containers for a fluid sample containing a radionuclide for measurement of radiation from the radionuclide include an outer shell having one or more ports between an interior and an exterior of the outer shell, and an inner shell secured to the outer shell. The inner shell includes a detector receptacle sized for at least partial insertion into the outer shell. The inner shell and outer shell together at least partially define a fluid sample space. The outer shell and inner shell are configured for maintaining an operating pressure within the fluid sample space of at least about 1000 psi. Systems for measuring radioactivity in a fluid include such a container and a radiation detector received at least partially within the detector receptacle. Methods of measuring radioactivity in a fluid sample include maintaining a pressure of a fluid sample within a Marinelli-type container at least at about 1000 psi. |
| FILED | Thursday, August 13, 2015 |
| APPL NO | 14/826056 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0055 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684221 | Luo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Liang Luo (Ames, Iowa); Jigang Wang (Ames, Iowa); Thomas Koschny (Ames, Iowa); Martin Wegener (Karlsruhe, Germany); Costas M. Soukoulis (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); Martin Wegener (Karlsruhe, Germany) |
| INVENTOR(S) | Liang Luo (Ames, Iowa); Jigang Wang (Ames, Iowa); Thomas Koschny (Ames, Iowa); Martin Wegener (Karlsruhe, Germany); Costas M. Soukoulis (Ames, Iowa) |
| ABSTRACT | Provided are systems and methods to generate single-cycle THz pulses from a few tens of nanometers thin layer of split ring resonators (SRRs) via optical rectification of femtosecond laser pulses. The emitted THz radiation, with a spectrum ranging from about 0.1 to 4 THz, arises exclusively from pumping the magnetic-dipole resonance of SRRs around 200 THz. This resonant enhancement, together with pump polarization dependence and power scaling of the THz emission, underpins the nonlinearity from optically induced circulating currents in SRRs, with a huge effective nonlinear susceptibility of 0.8×10−16 m2/V that far exceeds surface nonlinearities of both thin films and bulk organic/inorganic crystals and sheet nonlinearities of non-centrosymmetric materials such as ZnTe. |
| FILED | Wednesday, January 06, 2016 |
| APPL NO | 14/989565 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/225 (20130101) Original (OR) Class G02F 2203/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684234 | Darling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne LLC (Argonne, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Seth B. Darling (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Yu-Chih Tseng (Westmont, Illinois) |
| ABSTRACT | Simplified methods of multiple-patterning photolithography using sequential infiltration synthesis to modify the photoresist such that it withstands plasma etching better than unmodified resist and replaces one or more hard masks and/or a freezing step in MPL processes including litho-etch-litho-etch photolithography or litho-freeze-litho-etch photolithography. |
| FILED | Friday, May 24, 2013 |
| APPL NO | 13/902169 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class G03F 7/405 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0273 (20130101) H01L 21/3065 (20130101) H01L 21/3081 (20130101) H01L 21/3086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684951 | Wohlberg |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Brendt Wohlberg (Los Alamos, New Mexico) |
| ABSTRACT | Computationally efficient algorithms may be applied for fast dictionary learning solving the convolutional sparse coding problem in the Fourier domain. More specifically, efficient convolutional sparse coding may be derived within an alternating direction method of multipliers (ADMM) framework that utilizes fast Fourier transforms (FFT) to solve the main linear system in the frequency domain. Such algorithms may enable a significant reduction in computational cost over conventional approaches by implementing a linear solver for the most critical and computationally expensive component of the conventional iterative algorithm. The theoretical computational cost of the algorithm may be reduced from O(M3N) to O(MN log N), where N is the dimensionality of the data and M is the number of elements in the dictionary. This significant improvement in efficiency may greatly increase the range of problems that can practically be addressed via convolutional sparse representations. |
| FILED | Wednesday, March 25, 2015 |
| APPL NO | 14/668900 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 17/14 (20130101) Image Data Processing or Generation, in General G06T 5/004 (20130101) Original (OR) Class G06T 2207/20056 (20130101) Coding; Decoding; Code Conversion in General H03M 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685324 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Seung-Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Seung-Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
| ABSTRACT | Exemplary embodiments provide materials and methods of forming high-quality semiconductor devices using lattice-mismatched materials. In one embodiment, a composite film including one or more substantially-single-particle-thick nanoparticle layers can be deposited over a substrate as a nanoscale selective growth mask for epitaxially growing lattice-mismatched materials over the substrate. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 14/610254 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/005 (20130101) C30B 23/025 (20130101) C30B 25/04 (20130101) C30B 25/18 (20130101) C30B 25/183 (20130101) C30B 29/40 (20130101) C30B 29/42 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02381 (20130101) H01L 21/02433 (20130101) H01L 21/02455 (20130101) H01L 21/02458 (20130101) H01L 21/02505 (20130101) H01L 21/02513 (20130101) Original (OR) Class H01L 21/02538 (20130101) H01L 21/02546 (20130101) H01L 21/02636 (20130101) H01L 21/02642 (20130101) H01L 21/02647 (20130101) H01L 29/267 (20130101) H01L 29/0665 (20130101) H01L 29/0688 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685580 | Cruz-Campa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico); The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jose Luis Cruz-Campa (Waltham, Massachusetts); Xiaowang Zhou (Livermore, California); David Zubia (El Paso, Texas) |
| ABSTRACT | A photovoltaic solar cell comprises a nano-patterned substrate layer. A plurality of nano-windows are etched into an intermediate substrate layer to form the nano-patterned substrate layer. The nano-patterned substrate layer is positioned between an n-type semiconductor layer composed of an n-type semiconductor material and a p-type semiconductor layer composed of a p-type semiconductor material. Semiconductor material accumulates in the plurality of nano-windows, causing a plurality of heterojunctions to form between the n-type semiconductor layer and the p-type semiconductor layer. |
| FILED | Wednesday, September 14, 2016 |
| APPL NO | 15/265374 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/06 (20130101) H01L 31/065 (20130101) H01L 31/073 (20130101) H01L 31/0352 (20130101) H01L 31/0725 (20130101) H01L 31/1832 (20130101) Original (OR) Class H01L 31/03529 (20130101) H01L 31/035281 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/543 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685600 | Washington, II et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Aaron L. Washington, II (Aiken, South Carolina); Joseph A. Teprovich (Aiken, South Carolina); Ragaiy Zidan (Aiken, South Carolina) |
| ABSTRACT | Methods for enhancing characteristics of superconductive fullerenes and devices incorporating the fullerenes are disclosed. Enhancements can include increase in the critical transition temperature at a constant magnetic field; the existence of a superconducting hysteresis over a changing magnetic field; a decrease in the stabilizing magnetic field required for the onset of superconductivity; and/or an increase in the stability of superconductivity over a large magnetic field. The enhancements can be brought about by transmitting electromagnetic radiation to the superconductive fullerene such that the electromagnetic radiation impinges on the fullerene with an energy that is greater than the band gap of the fullerene. |
| FILED | Wednesday, February 18, 2015 |
| APPL NO | 14/625219 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/0213 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/24 (20130101) H01L 39/123 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685651 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ESS TECH, INC. (Portland, Oregon) |
| ASSIGNEE(S) | ESS Tech, Inc. (Portland, Oregon) |
| INVENTOR(S) | Craig Evans (West Linn, Oregon); Yang Song (West Linn, Oregon) |
| ABSTRACT | In one example, a system for a flow cell for a flow battery, comprising: a first flow field; and a polymeric frame, comprising: a top face; a bottom face, opposite the top face; a first side; a second side, opposite the first side; a first electrolyte inlet located on the top face and the first side of the polymeric frame; a first electrolyte outlet located on the top face and the second side of the polymeric frame; a first electrolyte inlet flow path located within the polymeric frame and coupled to the first electrolyte inlet; and a first electrolyte outlet flow path located within the polymeric frame and coupled to the first electrolyte outlet. In this way, shunt currents may be minimized by increasing the length and/or reducing the cross-sectional area of the electrolyte inlet and electrolyte outlet flow paths. |
| FILED | Thursday, September 05, 2013 |
| APPL NO | 14/019491 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/361 (20130101) Original (OR) Class H01M 2/362 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/4757 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685652 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jianlin Li (Knoxville, Tennessee); Beth L. Armstrong (Clinton, Tennessee); Claus Daniel (Knoxville, Tennessee); David L. Wood, III (Knoxville, Tennessee) |
| ABSTRACT | A method of making a battery electrode includes the steps of dispersing an active electrode material and a conductive additive in water with at least one dispersant to create a mixed dispersion; treating a surface of a current collector to raise the surface energy of the surface to at least the surface tension of the mixed dispersion; depositing the dispersed active electrode material and conductive additive on a current collector; and heating the coated surface to remove water from the coating. |
| FILED | Tuesday, January 06, 2015 |
| APPL NO | 14/590572 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/068 (20130101) B05D 3/142 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 99/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/62 (20130101) H01M 4/136 (20130101) H01M 4/139 (20130101) H01M 4/0404 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 4/1391 (20130101) H01M 4/1397 (20130101) H01M 4/5825 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/948 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685684 | Lambert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Timothy N. Lambert (Albuquerque, New Mexico); Michael Hibbs (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus includes an electrochemical half-cell comprising: an electrolyte, an anode; and an ionomeric barrier positioned between the electrolyte and the anode. The anode may comprise a multi-electron vanadium phosphorous alloy, such as VPx, wherein x is 1-5. The electrochemical half-cell is configured to oxidize the vanadium and phosphorous alloy to release electrons. A method of mitigating corrosion in an electrochemical cell includes disposing an ionomeric barrier in a path of electrolyte or ion flow to an anode and mitigating anion accumulation on the surface of the anode. |
| FILED | Tuesday, July 16, 2013 |
| APPL NO | 13/943566 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 12/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685765 | Sinclair et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael B. Sinclair (Albuquerque, New Mexico); Larry K. Warne (Albuquerque, New Mexico); Lorena I. Basilio (Albuquerque, New Mexico); William L. Langston (Albuquerque, New Mexico); Salvatore Campione (Albuquerque, New Mexico); Igal Brener (Albuquerque, New Mexico); Sheng Liu (Albuquerque, New Mexico) |
| ABSTRACT | A new monolithic resonator metasurface design achieves ultra-high Q-factors while using only one resonator per unit cell. The metasurface relies on breaking the symmetry of otherwise highly symmetric resonators to induce intra-resonator mixing of bright and dark modes (rather than inter-resonator couplings), and is scalable from the near-infrared to radio frequencies and can be easily implemented in dielectric materials. The resulting high-quality-factor Fano metasurface can be used in many sensing, spectral filtering, and modulation applications. |
| FILED | Wednesday, August 03, 2016 |
| APPL NO | 15/227440 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/12 (20130101) Original (OR) Class H01S 5/1042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685904 | Cioffi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Philip Michael Cioffi (Schaghticoke, New York); Maja Harfman Todorovic (Niskayuna, New York); Michael Scott Herzog (Voorheesville, New York); Charles Steven Korman (Niskayuna, New York); Donald M. Doherty (Schenectady, New York); Neil Anthony Johnson (Niskayuna, New York) |
| ABSTRACT | A micro-inverter assembly includes a housing having an opening formed in a bottom surface thereof, and a direct current (DC)-to-alternating current (AC) micro-inverter disposed within the housing at a position adjacent to the opening. The micro-inverter assembly further includes a micro-inverter DC connector electrically coupled to the DC-to-AC micro-inverter and positioned within the opening of the housing, the micro-inverter DC connector having a plurality of exposed electrical contacts. |
| FILED | Wednesday, October 16, 2013 |
| APPL NO | 14/055024 |
| ART UNIT | 1756 — Electrical Circuits and Systems |
| CURRENT CPC | Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/00 (20130101) H02S 40/32 (20141201) H02S 40/34 (20141201) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685953 | Sadowski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Sunnyvale, California) |
| INVENTOR(S) | Greg Sadowski (Cambridge, Massachusetts) |
| ABSTRACT | In one form, a logic circuit includes an asynchronous logic circuit, a synchronous logic circuit, and an interface circuit coupled between the asynchronous logic circuit and the synchronous logic circuit. The asynchronous logic circuit has a plurality of asynchronous outputs for providing a corresponding plurality of asynchronous signals. The synchronous logic circuit has a plurality of synchronous inputs corresponding to the plurality of asynchronous outputs, a stretch input for receiving a stretch signal, and a clock output for providing a clock signal. The synchronous logic circuit provides the clock signal as a periodic signal but prolongs a predetermined state of the clock signal while the stretch signal is active. The asynchronous interface detects whether metastability could occur when latching any of the plurality of the asynchronous outputs of the asynchronous logic circuit using said clock signal, and activates the stretch signal while the metastability could occur. |
| FILED | Friday, September 09, 2016 |
| APPL NO | 15/261438 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 19/00315 (20130101) Original (OR) Class H03K 19/01855 (20130101) H03K 19/018521 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686125 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Schweitzer Engineering Laboratories, Inc. (Pullman, Washington) |
| ASSIGNEE(S) | Schwetizer Engineering Laboratories, Inc. (Pullman, Washington) |
| INVENTOR(S) | Rhett Smith (Kuna, Idaho); Marc Ryan Berner (Monroe, Washington); Jason A. Dearien (Moscow, Idaho); Josh Powers (Pullman, Washington) |
| ABSTRACT | The present disclosure pertains to systems and methods for assessing reliability of communication links in a software defined network (SDN). In one embodiment, a system may include an SDN architecture subsystem configured to generate SDN architecture information and a bandwidth subsystem configured to generate bandwidth information. A latency subsystem may receive the bandwidth information from the bandwidth subsystem and may be configured to generate latency information using the bandwidth information. A failover subsystem may receive the SDN architecture information, the bandwidth information, and the latency information and generate a failover assessment and a failover route for the communication link. A reliability assessment subsystem may receive the SDN architecture information, the bandwidth information, and the latency information, and the failover assessment and generate a reliability assessment. A traffic routing subsystem may receive the reliability assessment and route data traffic to the failover route based on the reliability assessment. |
| FILED | Monday, July 20, 2015 |
| APPL NO | 14/803661 |
| ART UNIT | 2416 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/147 (20130101) H04L 41/0654 (20130101) Original (OR) Class H04L 47/122 (20130101) H04L 49/557 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686844 | Coleman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua Coleman (Santa Fe, New Mexico); Carl Ekdahl (Santa Fe, New Mexico); John Oertel (Los Alamos, New Mexico) |
| ABSTRACT | An intense X-ray or EUV light source may be driven by the Smith-Purcell effect. The intense light source may utilize intense electron beams and Bragg crystals. This may allow the intense light source to range from the extreme UV range up to the hard X-ray range. |
| FILED | Friday, April 01, 2016 |
| APPL NO | 15/088366 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | X-ray Technique H05G 2/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 09681647 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Huanhuan Chen (Flushing, New York); Steven M. Lipkin (Scarsdale, New York); Xiling Shen (Ithaca, New York) |
| ABSTRACT | Provided are compositions and methods that involve cancer cells which are modified so that they can form orthotopic tumors in a non-human mammal, and wherein metastasis of the tumor can be controlled. The cancer cells, which may be human cancer cells, are modified so that expression of a human chemokine receptor can be modulated. Modulating expression of the human chemokine receptor allows selective initiation of metastasis. Kits which contain the modified cancer cells are provided. A method for identifying agents which can inhibit metastasis using non-human mammals having orthotopic tumors formed using the modified cancer cells is also included. |
| FILED | Wednesday, July 03, 2013 |
| APPL NO | 14/412312 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 67/0278 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Peptides C07K 14/7158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2310/531 (20130101) C12N 2740/15043 (20130101) C12N 2830/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682157 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Southern Illinois University (Carbondale, Illinois) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (Carbondale, Illinois) |
| INVENTOR(S) | Yong Gao (Carbondale, Illinois); Boyd Goodson (Carbondale, Illinois) |
| ABSTRACT | Composition and method for surface-functionalized SPION-based agents. Such agents can provide highly pH-sensitive MRI contrast in tissue. |
| FILED | Tuesday, November 05, 2013 |
| APPL NO | 14/072637 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/186 (20130101) A61K 49/1857 (20130101) A61K 49/1872 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682168 | Joshi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Neel Satish Joshi (Somerville, Massachusetts); Daniel James Rubin (Cambridge, Massachusetts) |
| ABSTRACT | The disclosed subject matter can provide a nanotube-reinforced polymer composite material comprising a plurality of nanotubes, each nanotube being formed of a plurality of cyclic peptide molecules, disposed within a polymer matrix, such as a biodegradable polymer matrix. A cyclic polymer, such as a cyclic 8-mer, composed of amino acid residues of alternating absolute configurations (D/L, R/S), can self-assemble into nanotubes useful for preparation of the composite polymer material of the invention. For example, the cyclic peptide (QL)4, wherein the glutamine and leucine residues are of opposite absolute configuration, self-assembles into nanotubes, which when formed into a reinforced polymer composite including poly(caprolactone), provides a biocompatible material of greater tensile strength and Young's modulus compared to the poly(caprolactone) material alone. The nanotubes can be prepared by a vapor equilibration technique or by a solvent-nonsolvent precipitation technique. The materials of the invention can be used for implants, stents and the like as well as for synthetic ligaments, tendons, cartilage, and bone for use in the living tissue of a patient in need thereof. For example, a spinal fusion cage comprising a PDLLA polymer matrix with a plurality of nanotubes of the invention can exhibit enhanced stiffness. |
| FILED | Monday, November 26, 2012 |
| APPL NO | 14/360851 |
| ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0092 (20130101) A61K 47/42 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/26 (20130101) A61L 27/44 (20130101) A61L 27/44 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 31/125 (20130101) A61L 31/125 (20130101) A61L 31/129 (20130101) A61L 31/129 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) A61L 2430/10 (20130101) A61L 2430/34 (20130101) A61L 2430/38 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/22 (20130101) C08K 7/22 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 1/02 (20130101) C08L 5/04 (20130101) C08L 5/08 (20130101) C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 67/04 (20130101) C08L 89/00 (20130101) C08L 101/16 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0053 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683077 | Coates et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Geoffrey W. Coates (Ithaca, New York); Stephen Lee (Ithaca, New York); Zengquan Qin (Copley, Ohio); Nicholas J. Robertson (Ithaca, New York) |
| ABSTRACT | Copolymers of propylene oxide and carbon dioxide and homopolymers of propylene oxide are made using two dimensional double metal cyanide complexes having the formula Co[M(CN)4] or hydrated or partially dehydrated form thereof. There is no propylene carbonate by product in the copolymerization. |
| FILED | Thursday, March 26, 2015 |
| APPL NO | 14/669882 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Ammonia; Cyanogen; Compounds Thereof C01C 3/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 64/34 (20130101) C08G 64/0208 (20130101) Original (OR) Class C08G 65/2603 (20130101) C08G 65/2663 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683081 | Stahl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Shannon S. Stahl (Madison, Wisconsin); Samuel H. Gellman (Madison, Wisconsin); Sarah E. Lee (Madison, Wisconsin); Mehmet F. Ilker (Istanbul, Turkey); Bernard Weisblum (Madison, Wisconsin); Denis Kissounko (Broomfield, Colorado) |
| ABSTRACT | Disclosed is a method of making β-polypeptides. The method includes polymerizing β-lactam-containing monomers in the presence of a base initiator and a co-initiator which is not a metal-containing molecule to yield the product β-polypeptides. Specifically disclosed are methods wherein the base initiator is potassium t-butoxide, lithium bis(trimethylsilyl)amide (LiN(TMS)2), potassium bis(trimethyl-silyl)amide, and sodium ethoxide, and the reaction is carried out in a solvent such as chloroform, dichloromethane, dimethylsulfoxide, or tetrahydrofuran. |
| FILED | Tuesday, July 21, 2015 |
| APPL NO | 14/804619 |
| ART UNIT | 1676 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Heterocyclic Compounds C07D 205/08 (20130101) C07D 205/12 (20130101) Peptides C07K 1/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683993 | Linder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); OPKO Diagnostics, LLC (Woburn, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); OPKO Diagnostics, LLC (Woburn, Massachusetts) |
| INVENTOR(S) | Vincent Linder (Tewksbury, Massachusetts); Samuel K. Sia (New York, New York); George M. Whitesides (Newton, Massachusetts); Max Narovlyansky (Cambridge, Massachusetts); Adam Carlyn Siegel (New York, New York) |
| ABSTRACT | The present invention relates generally to microfluidic structures, and more specifically, to microfluidic structures and methods including meandering and wide channels. Microfluidic systems can provide an advantageous environment for performing various reactions and analyses due to a reduction in sample and reagent quantities that are required, a reduction in the size of the operating system, and a decrease in reaction time compared to conventional systems. Unfortunately, the small size of microfluidic channels can sometimes result in difficulty in detecting a species without magnifying optics (such as a microscope or a photomultiplier). A series of tightly packed microchannels, i.e., a meandering region, or a wide channel having a dimension on the order of millimeters, can serve as a solution to this problem by creating a wide measurement area. Although this invention mainly describes the use of meandering and wide channels in heterogeneous immunoassays on a microfluidic chip, this invention could be used for amplifying optical signals for other types of reactions and/or assays. |
| FILED | Wednesday, April 10, 2013 |
| APPL NO | 13/860160 |
| ART UNIT | 1677 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 2300/0636 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0883 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/82 (20130101) G01N 33/54366 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684127 | Qi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Minghao Qi (West Lafayette, Indiana); Li Fan (West Lafayette, Indiana); Jian Wang (West Lafayette, Indiana); Leo Tom Varghese (West Lafayette, Indiana) |
| ABSTRACT | An optical device includes a first optical cavity, a second optical cavity, a first light guide and a second light guide. Each of the first and second optical cavities is formed on a semiconductor substrate, and is configured to store light. The first light guide has an input, and is optically coupled to the first optical cavity by a first coupling strength. In addition, the first light guide is optically coupled to the second optical cavity by a second coupling strength. The second light guide has an output, and is coupled to the second optical cavity by a third coupling strength. The first coupling strength is greater than the second coupling strength, and the third coupling strength is greater than the second coupling strength. |
| FILED | Monday, October 15, 2012 |
| APPL NO | 14/382507 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) Original (OR) Class G02B 6/2746 (20130101) G02B 6/12007 (20130101) G02B 6/29343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685214 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Christopher S. Lynch (Sherman Oaks, California); Jizhai Cui (Los Angeles, California); Joshua Hockel (Los Angeles, California); Gregory P. Carman (Los Angeles, California) |
| ABSTRACT | Devices and methods for controlling magnetic anisotropy and orientation of magnetic single domain structures between stable states are provided based on piezoelectric thin films and patterned electrodes. By using patterned electrodes, piezoelectric strain is manipulated to achieve a highly localized biaxial strain in a piezoelectric substrate and rotate the magnetic anisotropy of magnetic materials. Reorientation of a magnetic single domain between different stable states is accomplished by pulsing voltage across pairs of electrodes. Since only a small region surrounding the electrodes is strained, the methods can be applied to arrays of indexed magnetic elements and to piezoelectric thin films clamped to silicon base substrates. |
| FILED | Monday, June 15, 2015 |
| APPL NO | 14/740147 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/14 (20130101) G11C 11/161 (20130101) G11C 11/1673 (20130101) Original (OR) Class G11C 11/1675 (20130101) G11C 2013/0095 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/047 (20130101) H01L 41/0926 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685559 | Duan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xiangfeng Duan (Los Angeles, California); Woojong Yu (Los Angeles, California); Yuan Liu (Los Angeles, California); Yu Huang (Los Angeles, California) |
| ABSTRACT | A vertically stacked heterostructure device includes: (1) a substrate; and (2) vertically stacked layers disposed over the substrate and including (a) a source electrode including a layer of graphene; (b) a drain electrode; and (c) a semiconducting channel disposed between the source electrode and the drain electrode. During operation of the device, a current is configured to flow between the source electrode and the drain electrode through the semiconducting channel. |
| FILED | Friday, December 20, 2013 |
| APPL NO | 14/654164 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/45 (20130101) H01L 29/1606 (20130101) H01L 29/7869 (20130101) Original (OR) Class H01L 29/41733 (20130101) H01L 29/41775 (20130101) H01L 29/66742 (20130101) H01L 29/66969 (20130101) H01L 29/78642 (20130101) H01L 29/78681 (20130101) H01L 29/78684 (20130101) H01L 29/78693 (20130101) H01L 29/78696 (20130101) H01L 31/032 (20130101) H01L 31/113 (20130101) H01L 31/022408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685878 | Balda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Juan Carlos Balda (Fayetteville, Arkansas); Andres Escobar Mejia (Fayetteville, Arkansas) |
| ABSTRACT | An electric power transmission system and method that provides a power electronic interface system for connecting a plurality of alternating current transmission lines by one or more direct current transmission lines. The system includes dc-link converters, frequency transformers connected to the converters, and multilevel converters are connected to a direct current transmission line. |
| FILED | Tuesday, December 02, 2014 |
| APPL NO | 14/558439 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/4585 (20130101) Original (OR) Class H02M 7/4807 (20130101) H02M 7/7575 (20130101) H02M 2007/4835 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686306 | Chizeck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Howard Jay Chizeck (Seattle, Washington); Tamara Bonaci (Seattle, Washington) |
| ABSTRACT | Methods and systems for securing remotely-operable devices are provided. A remotely-operable device can receive a command related to a component of the remotely-operable device operating in an environment. The remotely-operable device can include a reality-rules database (RRDB) that is configured to store a plurality of reality rules with each reality rule relating to a constraint on the remotely-operable device. The remotely-operable device can determine a reasonableness value for the command based on a constraint, where the constraint is determined based on a constraint related to at least one reality rule of the plurality of reality rules stored in the RRDB. The remotely-operable device can encode the reasonableness value for the command in a feedback message. The remotely-operable device can send the encoded feedback message from the remotely-operable device. |
| FILED | Wednesday, October 30, 2013 |
| APPL NO | 14/438722 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Electric Digital Data Processing G06F 19/3418 (20130101) G06F 19/3481 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/12 (20130101) H04L 63/1416 (20130101) H04L 63/1441 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09686867 | Rus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniela Rus (Weston, Massachusetts); Robert J. Wood (Cambridge, Massachusetts); Cagdas Denizel Onal (Cambridge, Massachusetts); Michael Tolley (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachussetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniela Rus (Weston, Massachusetts); Robert J. Wood (Cambridge, Massachusetts); Cagdas Denizel Onal (Cambridge, Massachusetts); Michael Tolley (Cambridge, Massachusetts) |
| ABSTRACT | Methods to systematize the development of machines using inexpensive, fast, and convenient fabrication processes are disclosed. In an embodiment, a folding pattern and corresponding circuit design can provide the blueprints for fabrication. The folding pattern may be provided (e.g. laser machined) on a flat sheet of substrate material, such as a polymer. The circuit pattern may be generated by etching or applying (e.g. sputtering) a copper foil layer onto the substrate. Circuit components and actuators may then be added at specified locations. The flat substrate may then be folded along the predefined locations to form the final machine. The machine may operate autonomously to perform a task. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 13/723364 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/028 (20130101) H05K 1/189 (20130101) Original (OR) Class H05K 3/0005 (20130101) H05K 3/06 (20130101) H05K 3/0052 (20130101) H05K 2201/052 (20130101) H05K 2201/053 (20130101) H05K 2201/0909 (20130101) H05K 2201/09063 (20130101) H05K 2203/1453 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4913 (20150115) Y10T 29/49155 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 09681620 | Hu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Gongshe Hu (Pocatello, Idaho) |
| ABSTRACT | The present disclosure relates to barley plants having grain with ultra-high beta-glucan content, methods for constructing said barley plants, grain therefrom and uses thereof. In an exemplary embodiment, present disclosure provides a barley plant having grain with ultra-high beta-glucan content known as CM1. |
| FILED | Thursday, April 10, 2014 |
| APPL NO | 14/249584 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683021 | Harris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Delbert L. Harris (Ames, Iowa); Matthew M. Erdman (Ames, Iowa) |
| ABSTRACT | The invention relates to a polypeptide of a protective antigenic determinant (PAD polypeptide) of porcine reproductive and respiratory syndrome virus (PRRSV) and nucleic acids encoding a PAD polypeptide. The PAD polypeptide and nucleic acids encoding a PAD polypeptide are useful in the development of antibodies directed to PAD, vaccines effective in providing protection against PRRSV infection, and diagnostic assays detecting the presence of PAD antibodies generated by a PAD-specific vaccine. The invention also discloses methods of generating antibodies to PAD, for vaccinating a pig to provide protection from PRRSV infections, a method of preparing the vaccine, a method of treating PRRSV infections in a pig, and a method of detecting antibodies to PAD of PRRSV. |
| FILED | Thursday, May 15, 2014 |
| APPL NO | 14/278015 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/295 (20130101) A61K 2039/552 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/10022 (20130101) C12N 2770/10034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 09682071 | Nicolls et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERMUNE, INC. (Brisbane, California); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | INTERMUNE, INC. (Brisbane, California); THE BOARD OF TRUSTEES OF THE LELAND STANFORD (Palo Alto, California) |
| INVENTOR(S) | Mark R. Nicolls (Palo Alto, California); Karl Kossen (Brisbane, California); Alan Cohen (Menlo Park, California) |
| ABSTRACT | The disclosure relates to methods of preserving or improving microvascular integrity in a patient in need thereof comprising administering pirfenidone therapy to the patient. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/772241 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/4412 (20130101) A61K 31/4418 (20130101) Original (OR) Class A61K 31/4427 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09683239 | Chu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Cong-Qiu Chu (Lake Oswego, Oregon) |
| ABSTRACT | A recombinant nucleic acid comprising an aptamer that binds CD4 and an RNAi sequence that silences the expression of RORγ2 is described herein. Pharmaceutical compositions comprising the recombinant nucleic acid, particularly topical compositions are also described. Methods of treating inflammatory disease using the pharmaceutical composition are also described. |
| FILED | Tuesday, September 22, 2015 |
| APPL NO | 14/862065 |
| ART UNIT | 1674 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 09685913 | Quilligan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Gerard T. Quilligan (Gulf Breeze, Florida); Shahid Aslam (Washington, District of Columbia) |
| ABSTRACT | An autozero amplifier may include a window comparator network to monitor an output offset of a differential amplifier. The autozero amplifier may also include an integrator to receive a signal from a latched window comparator network, and send an adjustment signal back to the differential amplifier to reduce an offset of the differential amplifier. |
| FILED | Thursday, September 10, 2015 |
| APPL NO | 14/850602 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 1/26 (20130101) Original (OR) Class H03F 3/45076 (20130101) H03F 2203/45116 (20130101) H03F 2203/45152 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685976 | Ardalan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micro RDC (Colorado Springs, Colorado) |
| ASSIGNEE(S) | MICROELECTRONICS RESEARCH and DEVELOPMENT CORP. (Colorado Springs, Colorado) |
| INVENTOR(S) | Sasan Ardalan (Alberquerque, New Mexico) |
| ABSTRACT | The invention relates to an improved K-Delta-1-Sigma Modulators (KG1Ss) that achieve multi GHz sampling rates with 90 nm and 45 nm CMOS processes, and that provide the capability to balance performance with power in many applications. The improved KD1Ss activate all paths when high performance is needed (e.g. high bandwidth), and reduce the effective bandwidth by shutting down multiple paths when low performance is required. The improved KD1Ss can adjust the baseband filtering for lower bandwidth, and can provide large savings in power consumption while maintaining the communication link, which is a great advantage in space communications. The improved KD1Ss herein provides a receiver that adjusts to accommodate a higher rate when a packet is received at a low bandwidth, and at a initial lower rate, power is saved by turning off paths in the KD1S Analog to Digital Converter, and where when a higher rate is required, multiple paths are enabled in the KD1S to accommodate the higher band widths. |
| FILED | Tuesday, June 23, 2015 |
| APPL NO | 14/747699 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 3/42 (20130101) H03M 3/454 (20130101) H03M 3/496 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 09682085 | Abdel-Meguid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shifa Biomedical Corporation (Malvern, Pennsylvania) |
| ASSIGNEE(S) | Shifa Biomedical Corporation (Malvern, Pennsylvania) |
| INVENTOR(S) | Sherin Salaheldin Abdel-Meguid (Exton, Pennsylvania); Nabil Elshourbagy (Chester, Pennsylvania); Harold Meyers (Weston, Pennsylvania); Shaker A. Mousa (Wynantskill, New York) |
| ABSTRACT | Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), as well as therapeutic methods for use of such compounds to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia. Examples of compounds include thiadiazole, isoxazole, 1,2,4-triazole, thiazole, indole, pyrazole, and pyrrolinone derivatives. |
| FILED | Tuesday, March 11, 2014 |
| APPL NO | 14/767133 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/404 (20130101) A61K 31/415 (20130101) A61K 31/426 (20130101) A61K 31/433 (20130101) A61K 31/4015 (20130101) A61K 31/4155 (20130101) A61K 31/4178 (20130101) A61K 31/4196 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/5377 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685088 | Trent et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARCHITECTURE TECHNOLOGY, INC. (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barry A. Trent (Chanhassen, Minnesota); Ranga S. Ramanujan (Medina, Minnesota); Fabio F. Pozzo (Minneapolis, Minnesota) |
| ABSTRACT | A communication travel plan generation system for a vehicle is provided. The vehicle includes a communication hub, a system input and at least one controller. The communication hub is housed in the vehicle and is configured to communicate with a plurality of spaced subscriber communication nodes. The system input is configured to receive mission-specific information. The at least one controller is in communication with the system input. Moreover, the at least one controller is configured to apply the mission-specific information to a mission planning system to generate a mission plan of the vehicle. The at least one controller is further configured to implement the communication travel plan generation system to automatically generate travel waypoints for the mission planning system based at least in part on the mission-specific information applied to the mission planning system. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/093826 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0022 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/047 (20130101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0026 (20130101) G08G 5/0034 (20130101) Original (OR) Class G08G 5/0043 (20130101) G08G 5/0086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 09681808 | Donohue et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Signal Solutions, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | Signal Solutions, LLC (Lexington, Kentucky) |
| INVENTOR(S) | Kevin Donohue (Lexington, Kentucky); Bruce O'Hara (Lexington, Kentucky); Sridhar Sunderam (Lexington, Kentucky); Farid Yaghouby (Lexington, Kentucky) |
| ABSTRACT | Monitoring behavior of a rodent within a cage includes applying a vibration stimulus to a component of the cage and after applying the vibration stimulus, sensing a signal from a piezoelectric sensor within the cage, the sensed signal indicative of a behavioral response of the rodent. A plurality of attributes of the signal can be determined and the attributes can then be stored in a manner that associates the behavioral response of the rodent with the vibration stimulus. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 14/870286 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/0051 (20130101) Original (OR) Class A61B 5/4809 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684957 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hong Wu (Tempe, Arizona); Kun Deng (Phoenix, Arizona); Jianming Liang (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Hong Wu (Tempe, Arizona); Kun Deng (Phoenix, Arizona); Jianming Liang (Phoenix, Arizona) |
| ABSTRACT | Systems, methods, and media for detecting an anatomical object in a medical device image are provided. In some embodiments, system for detecting an anatomical object in a medical device image are provided, the systems comprising: at least one hardware processor that: applies the medical device image to a classifier having a plurality of stages, wherein a first stage of the plurality of stages and a second stage of the plurality of stages each includes a strong learner formed from a plurality of weak learners, and the weak learners in the second stage include a plurality of the weak learners included in the first stage; and identifies the medical device image as being positive or negative of showing the anatomical object based on the application the medical device image to be classifier. |
| FILED | Monday, February 13, 2012 |
| APPL NO | 13/984808 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6231 (20130101) G06K 9/6257 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 09686268 | Resch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CLEVERSAFE, INC. (Chicago, Illinois) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Jason K. Resch (Chicago, Illinois); Wesley Leggette (Chicago, Illinois); Bart Cilfone (Chicago, Illinois) |
| ABSTRACT | A method begins by a processing module receiving a dispersed storage network (DSN) access request that includes a requester identifier (ID), wherein the requester ID is associated with a certificate chain. When the certificate chain is valid, the method continues with the processing module accessing registry information for the DSN. The method continues with the processing module identifying one of a plurality of access control lists based on at least one of information associated with the requester ID and information associated with the certificate chain, identifying one or more entries of the one of the plurality of access control lists based on the information associated with the certificate chain to produce one or more identified entries, and generating, for the DSN access request, permissions from one or more sets of permissions associated with the one or more identified entries. |
| FILED | Monday, January 06, 2014 |
| APPL NO | 14/148118 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3265 (20130101) H04L 63/0823 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 09681808 | Donohue et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Signal Solutions, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | Signal Solutions, LLC (Lexington, Kentucky) |
| INVENTOR(S) | Kevin Donohue (Lexington, Kentucky); Bruce O'Hara (Lexington, Kentucky); Sridhar Sunderam (Lexington, Kentucky); Farid Yaghouby (Lexington, Kentucky) |
| ABSTRACT | Monitoring behavior of a rodent within a cage includes applying a vibration stimulus to a component of the cage and after applying the vibration stimulus, sensing a signal from a piezoelectric sensor within the cage, the sensed signal indicative of a behavioral response of the rodent. A plurality of attributes of the signal can be determined and the attributes can then be stored in a manner that associates the behavioral response of the rodent with the vibration stimulus. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 14/870286 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/0051 (20130101) Original (OR) Class A61B 5/4809 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 09683855 | Bonnell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Clayton C. Bonnell (Fairfax, Virginia); Neri G. Terry, Jr. (Springfield, Virginia); Kurt J. Schulz (Ballwin, Missouri) |
| ABSTRACT | A method and system for generating a location identification grid and for using a location identification grid. The location identification grid can include a first geographic area that correspond to a pre-existing area. This pre-existing area can correspond to a postal code such as a zip code, a telephone code such as, an area code, or any other desired pre-existing area. The location identification grid can be subdivided into smaller geographic areas to allow more accurate identification of a location. The location identification grid can include a second geographic area. The second geographic area can be a subdivision of the first geographic area. The location identification grid can be used with signals that identify a location within a location identification grid. These signals can include a first component corresponding to the first geographic area and the second component corresponding to one or more second geographic areas. |
| FILED | Tuesday, September 08, 2015 |
| APPL NO | 14/848120 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/00 (20130101) G01C 21/20 (20130101) G01C 21/34 (20130101) Original (OR) Class G01C 21/3667 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 29/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 09681648 | Roh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POSTECH ACADEMY-INDUSTRY FOUNDATION (Gyeongsangbuk-do, South Korea) |
| ASSIGNEE(S) | POSTECH ACADEMY-INDUSTRY FOUNDATION (, South Korea) |
| INVENTOR(S) | Tae Young Roh (Gyeongsangbuk-do, South Korea); Seung-Jae Lee (Gyeongsangbuk-do, South Korea); Murat Artan (Gyeongsangbuk-do, South Korea); Yuna Kim (Seoul, South Korea); Hong Gil Nam (Daegu, South Korea) |
| ABSTRACT | Provided are transgenic Caenorhabditis elegans (C. elegans) overexpressing DNA methyltransferase 3a (Dnmt3a) and a method of producing the same. According to the method, a specific mechanism and related factors for DNA methylation mediated by Dnmt3a may be found, and a critical gene for regulating the life span of C. elegans may be identified, and therefore C. elegans may be used as an animal model for screening a drug for a DNA methylation-related disease. |
| FILED | Wednesday, October 14, 2015 |
| APPL NO | 14/882977 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0336 (20130101) Original (OR) Class A01K 2217/00 (20130101) A01K 2227/703 (20130101) A01K 2267/0331 (20130101) A01K 2267/0393 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) C12N 2015/859 (20130101) C12N 2015/8536 (20130101) C12N 2015/8572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09682123 | Leibel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Rudolph L. Leibel (New York, New York); Kazuhisa Watanabe (Shimotsuke, Japan); Wendy K. Chung (Hackensack, New Jersey); Stuart G. Fischer (New Rochelle, New York); Charles Leduc (Hackensack, New Jersey); Elizabeth Watson (New York, New York); Maria Laura Cremona (Englewood, New Jersey) |
| ABSTRACT | The invention provides methods for treating metabolic disease in a subject and methods for increasing the expression of ILDR2 in a subject. The invention further provides a method for identifying an agent which modulates expression of an Ildr2 RNA comprising contacting a cell with an agent; determining expression of the Ildr2 RNA in the presence and the absence of the agent; and comparing expression of the Ildr2 RNA in the presence and the absence of the agent, wherein a change in the expression of the Ildr2 RNA in the presence of the agent is indicative of an agent which modulates the level of expression of the RNA. |
| FILED | Monday, December 22, 2014 |
| APPL NO | 14/579913 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/075 (20130101) A01K 2217/206 (20130101) A01K 2227/105 (20130101) A01K 2267/0362 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 38/1774 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 48/00 (20130101) Peptides C07K 14/70503 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09684146 | Marcinuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Adam J. Marcinuk (Lyndeborough, New Hampshire); Michael J. Shaw (Concord, New Hampshire); David E. Thompson (Nashua, New Hampshire) |
| ABSTRACT | A temperature insensitive locking apparatus for use with large optical mounts having at least one locking nut having an internal threaded portion adjacent to an internal tapered portion, at least one flexurized spring collet attached to a rigid base structure having an external threaded portion and a plurality of tapered flexures, a pivot shaft engaged with an optical yoke on a rotational axis of symmetry wherein when the internal threads of the locking nut engage with the external threads of the flexurized spring collet an increased level of a radial clamping force is provided around the pivot shaft. |
| FILED | Friday, September 19, 2014 |
| APPL NO | 14/769895 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 11/103 (20130101) Optical Elements, Systems, or Apparatus G02B 7/008 (20130101) Original (OR) Class G02B 7/181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09685258 | Silverman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia); Minnesota Wire and Cable (St. Paul, Minnesota) |
| ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia); Minnesota Wine and Cable (St. Paul, Minnesota) |
| INVENTOR(S) | Edward M. Silverman (Encino, California); James Grant (Redondo Beach, California); Thomas Kukowski (Apple Valley, Minnesota); Michael Matuszewski (Eagan, Minnesota); Kevin Voigt (St. Paul, Minnesota); Thomas Swanson (Chicago City, Minnesota); Phillip Hayes (Torrance, California) |
| ABSTRACT | A cable comprising hybrid carbon nanotube (CNT) shielding includes at least one conducting wire; at least one insulating layer covering at least one of the at least one conducting wire; a metallic foil component configured for lower frequency shielding function; and a CNT tape component configured for higher frequency shielding function. |
| FILED | Friday, November 09, 2012 |
| APPL NO | 13/673063 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 99/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 11/183 (20130101) H01B 11/1008 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 9/0518 (20130101) H01R 24/20 (20130101) H01R 2103/00 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 15/02 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/932 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 20, 2017.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20170620.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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