FedInvent™ Patents
Patent Details for Tuesday, July 04, 2017
This page was updated on Monday, March 27, 2023 at 05:15 AM GMT
Department of Health and Human Services (HHS)
US 09693692 | Deisseroth et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Karl Deisseroth (Palo Alto, California); Raag D. Airan (Menlo Park, California); Leslie A. Meltzer (Palo Alto, California) |
ABSTRACT | Various aspects are directed to systems and methods for assessing neural activity of a neural region having multiple subfields. In certain embodiments, a method includes evoking a cellular electrical response in at least one subfield due to neural activity in the neural region, capturing image data of the electrical response at a level sufficiently detailed in space and time to differentiate between polarization-based events of two respective portions of the subfield, and then assessing neural activity by correlating space and time information, from the captured data, for the two respective portions of the sub-field. Other more specific aspects of the invention involve different preparation and neural stimulation approaches which can vary depending on the application. |
FILED | Friday, February 08, 2013 |
APPL NO | 13/763132 |
ART UNIT | 3768 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) Original (OR) Class A61B 5/4848 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/6452 (20130101) G01N 2021/217 (20130101) G01N 2021/218 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09693732 | Tarler |
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APPLICANT(S) | Matthew D Tarler (Avon, Ohio) |
ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
INVENTOR(S) | Matthew D Tarler (Avon, Ohio) |
ABSTRACT | The present invention is related, in general, to an electrode patch and/or a wireless system for measuring the physiological condition of a subject, and more particularly to an electrode patch for ECG monitoring. The present invention further includes a method of sensing, analyzing and/or transmitting or relaying a physiological signal. The wireless system and/or electrode patch of the present invention is preferably lightweight and compact. The electrode patch preferably additionally provides a low, power system for extended battery life and use. The electrode patch and wireless system of the present invention still further preferably allows for good and reliable measurement of physiological signals form the subject. The electrode patch is still preferably simple to apply as a single patch, but versatile enough to be reconfigured as more than one patch. |
FILED | Thursday, August 27, 2015 |
APPL NO | 14/837432 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0478 (20130101) A61B 5/0492 (20130101) A61B 5/0496 (20130101) A61B 5/04085 (20130101) A61B 5/6833 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09693954 | Mooney et al. |
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APPLICANT(S) | David J. Mooney (Sudbury, Massachusetts); William W. Yuen (Chicago, Illinois); Praveen Arany (Fairfax, Virginia) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | David J. Mooney (Sudbury, Massachusetts); William W. Yuen (Chicago, Illinois); Praveen Arany (Fairfax, Virginia) |
ABSTRACT | The invention provides methods and compositions for local manipulation of regenerative processes via exogenous factor delivery. |
FILED | Monday, June 27, 2011 |
APPL NO | 13/805840 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/30756 (20130101) A61F 2002/30766 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0087 (20130101) Original (OR) Class A61K 31/16 (20130101) A61K 31/16 (20130101) A61K 31/335 (20130101) A61K 31/335 (20130101) A61K 31/381 (20130101) A61K 31/381 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/4192 (20130101) A61K 31/4192 (20130101) A61K 35/12 (20130101) A61K 35/28 (20130101) A61K 35/28 (20130101) A61K 35/545 (20130101) A61K 35/545 (20130101) A61K 38/185 (20130101) A61K 38/185 (20130101) A61K 38/1808 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 38/1866 (20130101) A61K 38/1866 (20130101) A61K 38/1875 (20130101) A61K 38/1875 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09693957 | Lin et al. |
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APPLICANT(S) | Wenbin Lin (Chapel Hill, North Carolina); Demin Liu (Carrboro, North Carolina); Joseph Della Rocca (Chapel Hill, North Carolina); Stephanie A. Kramer (Chapel Hill, North Carolina); Christopher Y. Poon (Carrboro, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Wenbin Lin (Chapel Hill, North Carolina); Demin Liu (Carrboro, North Carolina); Joseph Della Rocca (Chapel Hill, North Carolina); Stephanie A. Kramer (Chapel Hill, North Carolina); Christopher Y. Poon (Carrboro, North Carolina) |
ABSTRACT | Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents. |
FILED | Monday, July 09, 2012 |
APPL NO | 14/131575 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/0019 (20130101) A61K 9/127 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 9/5123 (20130101) A61K 9/5146 (20130101) A61K 31/663 (20130101) A61K 31/675 (20130101) A61K 47/48884 (20130101) A61K 49/00 (20130101) A61K 51/1244 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09693994 | Montminy |
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APPLICANT(S) | Research Development Foundation (Carson City, Nevada) |
ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
INVENTOR(S) | Marc Montminy (La Jolla, California) |
ABSTRACT | In some aspects, methods for treating a bacterial infection in a mammalian subject are provided. In some embodiments, a class IIa HDAC inhibitor such as, e.g., a HDAC4 inhibitor, may be used to treat a bacterial infection such as, e.g., anthrax, pertussis, tuberculosis, or cholera. |
FILED | Thursday, April 09, 2015 |
APPL NO | 14/682263 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/20 (20130101) A61K 31/40 (20130101) Original (OR) Class A61K 31/137 (20130101) A61K 31/165 (20130101) A61K 31/166 (20130101) A61K 39/40 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09693998 | Pavliv et al. |
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APPLICANT(S) | Cumberland Pharmaceuticals Inc. (Nashville, Tennessee); Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | Cumberland Pharmaceuticals, Inc. (Nashville, Tennessee); Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Leo Pavliv (Cary, North Carolina); Bryan Voss (Nashville, Tennessee); James West (Nashville, Tennessee); Erica Carrier (Nashville, Tennessee) |
ABSTRACT | The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof. |
FILED | Monday, May 18, 2015 |
APPL NO | 14/715143 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/421 (20130101) Original (OR) Class A61K 31/422 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09693999 | Dunman et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF ROCHESTER (Rochester, New York); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | University of Rochester (Rochester, New York); Board of Regents of the University of Nebraska (Lincoln, Nebraska); Temple University Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
INVENTOR(S) | Paul M. Dunman (Pittsford, New York); Patrick D. Olson (St. Louis, Missouri); Wayne Childers (New Hope, Pennsylvania) |
ABSTRACT | Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection. |
FILED | Thursday, November 05, 2015 |
APPL NO | 14/933804 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/341 (20130101) A61K 31/402 (20130101) A61K 31/427 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 207/337 (20130101) C07D 307/56 (20130101) C07D 307/68 (20130101) C07D 405/06 (20130101) C07D 417/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/922 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694005 | Njar et al. |
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APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
INVENTOR(S) | Vincent C. O. Njar (Glen Burnie, Maryland); Puranik Purushottamachar (Gaithersburg, Maryland) |
ABSTRACT | Nonsteroid and steroid compounds that cause down-regulation of the androgen receptor (AR), both full length and splice variant, induce apoptosis and inhibit proliferation of inhibiting proliferation and migration of androgen sensitive cancer cells. The steroid compounds and nonsteroid compounds may be agents for the prevention and/or treatment of cancer, including prostate cancer, castration resistant prostate cancer, bladder cancer, pancreatic cancer, hepatocellular carcinoma, benign prostatic hyperplasia (BPH), Kennedy's disease, androgenetic alopecia, breast cancer, androgen-insensitive syndrome, and spinal and bulbar muscular atrophy. |
FILED | Friday, April 04, 2014 |
APPL NO | 14/781437 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4164 (20130101) A61K 31/4184 (20130101) A61K 31/4409 (20130101) A61K 31/4725 (20130101) Original (OR) Class Heterocyclic Compounds C07D 235/08 (20130101) C07D 401/10 (20130101) C07D 401/14 (20130101) C07D 403/10 (20130101) C07D 403/12 (20130101) Steroids C07J 43/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694032 | Katti et al. |
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APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
ASSIGNEE(S) | The Curators of University of Missouri (Columbia, Missouri) |
INVENTOR(S) | Kattesh V. Katti (Columbia, Missouri); Raghuraman Kannan (Columbia, Missouri); Kavita K. Katti (Columbia, Missouri); Nripen Chanda (Columbia, Missouri); Ravi Shukla (Columbia, Missouri) |
ABSTRACT | The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from soy or lentil plant material or a reactive extract thereof of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making biocompatible stabilized gold nanoparticles. The nanoparticles can be introduced in vivo to conduct enhanced imaging. The nanoparticles can also be introduced in vivo to conduct therapy. |
FILED | Friday, October 25, 2013 |
APPL NO | 14/063682 |
ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5176 (20130101) A61K 9/5192 (20130101) A61K 33/24 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2991 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694033 | Yi et al. |
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APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
INVENTOR(S) | Qing Yi (Cleveland, Ohio); Yong Lu (Cleveland, Ohio) |
ABSTRACT | A method of producing a population of CD8+ Tc9 lymphocytes is provided including priming a population of naïve CD8+ T cells by contacting the population of naïve CD8+ T cells with an immunogenic peptide, in the presence of a Tc9 supportive environment, thereby producing a population of CD8+ Tc9 lymphocytes which secrete IL-9. Purified populations of CD8+ Tc9 cells are also disclosed herein, as are method for their use in the treatment of cancer in a subject. |
FILED | Monday, January 26, 2015 |
APPL NO | 14/605112 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) A61K 35/17 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 2501/15 (20130101) C12N 2501/24 (20130101) C12N 2501/2302 (20130101) C12N 2501/2304 (20130101) C12N 2501/2312 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694049 | Burkin et al. |
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APPLICANT(S) | Dean Burkin (Sparks, Nevada); Ryan Wuebbles (Sparks, Nevada); Pam Van Ry (Reno, Nevada) |
ASSIGNEE(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNITVERSITY OF NEVADA, RENO (Reno, Nevada) |
INVENTOR(S) | Dean Burkin (Sparks, Nevada); Ryan Wuebbles (Sparks, Nevada); Pam Van Ry (Reno, Nevada) |
ABSTRACT | Disclosed herein are methods for diagnosing, prognosing and treating muscular dystrophy. The disclosed methods can be used to diagnosis, prognosis or treat a subject with merosin-deficient congenital muscular dystrophy Type 1A (MDC1A), limb-girdle muscular dystrophy (LGMD), facioscapulohumeral (FHMD), Beckers muscular dystrophy (BMD) or Duchenne muscular dystrophy (DMD). Also disclosed are methods of determining the effectiveness of an agent for the treatment of muscular dystrophy. In an example, a method of diagnosing or prognosing a subject with muscular dystrophy includes detecting expression of Galectin-1 or Galectin-3 in a sample obtained from the subject at risk of having or having one or more signs or symptoms associated with muscular dystrophy, thereby diagnosing or prognosing the subject with muscular dystrophy. Also provided are methods of enhancing muscle regeneration, repair, or maintenance in a subject by administering galectin, such as Galectin-1 and/or Galectin-3 to a subject in need thereof. |
FILED | Friday, August 10, 2012 |
APPL NO | 13/572508 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class A61K 38/1732 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2333/42 (20130101) G01N 2333/4724 (20130101) G01N 2500/00 (20130101) G01N 2800/52 (20130101) G01N 2800/2878 (20130101) G01N 2800/2885 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694050 | Phipps et al. |
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APPLICANT(S) | Richard P. Phipps (Pittsford, New York); Collynn F. Woeller (Webster, New York); Steven E. Feldon (Rochester, New York) |
ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Richard P. Phipps (Pittsford, New York); Collynn F. Woeller (Webster, New York); Steven E. Feldon (Rochester, New York) |
ABSTRACT | The present invention relates to methods of treating a condition involving excessive adipogenesis. This method relates to selecting a subject having a condition involving excessive adipogenesis and administering to the selected subject a composition comprising a Thy1 protein or polypeptide fragment thereof, or an agent that enhances Thy1 expression, under conditions effective to treat the condition. The present invention also relates to isolated nucleic acid molecules encoding a Thy1 protein or the fragment thereof and pharmaceutical formulations including such a protein or fragment thereof or an agent that enhances Thy1 expression and a pharmaceutically acceptable carrier. The present invention also relates to methods of inhibiting adipogenesis and/or decreasing adipocyte size, as well as methods of screening a candidate compound for its ability to influence adipogenesis. |
FILED | Monday, October 21, 2013 |
APPL NO | 14/437378 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0048 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 38/1774 (20130101) Peptides C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/113 (20130101) C12N 2310/141 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694051 | Hsu et al. |
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APPLICANT(S) | Sheau Yu Hsu (Menlo Park, California); Chia Lin Chang (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Sheau Yu Hsu (Menlo Park, California); Chia Lin Chang (Palo Alto, California) |
ABSTRACT | Long-acting agonistic analogs for CLR/RAMP receptors are provided that have an extended half-live in vivo. |
FILED | Thursday, April 05, 2012 |
APPL NO | 14/110098 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/22 (20130101) Original (OR) Class A61K 47/48 (20130101) Peptides C07K 14/575 (20130101) C07K 16/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694058 | Ware et al. |
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APPLICANT(S) | Carl F Ware (Solana Beach, California); Timothy C. Cheung (Wollstonecraft, Australia); Theresia A. Banks (San Diego, California) |
ASSIGNEE(S) | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (La Jolla, California) |
INVENTOR(S) | Carl F Ware (Solana Beach, California); Timothy C. Cheung (Wollstonecraft, Australia); Theresia A. Banks (San Diego, California) |
ABSTRACT | The tumor-necrosis factor superfamily member LIGHT (p30; TNFSF-14) is a cytokine for inducing immune responses against tumors. A novel biochemical approach is used to decorate the surface of tumor cells with LIGHT. LIGHT decorated cells can be used to vaccinate and induce effective, sustained immunity against cells expressing neo or pathogen associated antigens. Variants of LIGHT are described that enhance binding to cellular receptors (e.g., LT beta receptor) and decrease regulation by inhibitors (e.g., Decoy Receptor 3) increasing ability to stimulate immunity. |
FILED | Thursday, October 25, 2007 |
APPL NO | 12/446729 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 2039/5152 (20130101) A61K 2039/6006 (20130101) Peptides C07K 14/70575 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) C12N 5/0672 (20130101) C12N 2501/11 (20130101) C12N 2501/33 (20130101) C12N 2501/105 (20130101) C12N 2503/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694060 | Wong |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Albert J. Wong (Menlo Park, California) |
ABSTRACT | Peptides and vaccine compositions comprising peptides based upon EGFRvIII and lacking a glycine at the splice junction are disclosed. The vaccines can induce immune responses against EGFRvIII. Methods of inhibiting formation or growth of EGFvIII tumors, methods of inducing regression of EGFvIII tumors, methods of immunizing against EGFvIII tumors and methods of treating a subjects who have EGFvIII tumors are disclosed. |
FILED | Friday, August 02, 2013 |
APPL NO | 14/417752 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 47/4833 (20130101) A61K 47/48284 (20130101) A61K 2039/6081 (20130101) Peptides C07K 7/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694061 | Wang et al. |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Xinhui Wang (Boston, Massachusetts); Soldano Ferrone (Boston, Massachusetts) |
ABSTRACT | Disclosed herein are isolated human monoclonal antibodies, and functional fragments thereof, that specifically bind HMW-MAA. Nucleic acids encoding these antibodies, expression vectors including these nucleic acid molecules, and isolated host cells that express the nucleic acid molecules are also disclosed. The antibodies can be used to detect HMW-MAA in a sample. Methods of diagnosing cancer, or confirming a diagnosis of cancer, are disclosed herein that utilize these antibodies. Methods of treating a subject with cancer are also disclosed. |
FILED | Tuesday, October 20, 2015 |
APPL NO | 14/887700 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 2039/505 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Peptides C07K 14/705 (20130101) C07K 16/30 (20130101) C07K 16/3053 (20130101) C07K 2316/96 (20130101) C07K 2317/21 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/75 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/62 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) G01N 33/57423 (20130101) G01N 2400/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694072 | North |
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FUNDED BY |
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APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
INVENTOR(S) | William G. North (Hanover, New Hampshire) |
ABSTRACT | The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2. Methods for preventing and treating neuroendocrine cancers are also disclosed. |
FILED | Monday, October 27, 2014 |
APPL NO | 14/524483 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 31/439 (20130101) A61K 33/06 (20130101) A61K 39/39558 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/286 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 2333/70571 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694081 | Burdick et al. |
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FUNDED BY |
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APPLICANT(S) | Jason Alan Burdick (Philadelphia, Pennsylvania); Robert C. Gorman (Lower Gwynedd, Pennsylvania); Joseph H. Gorman, III (Lower Gwynedd, Pennsylvania); Brendan Patrick Purcell (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Jason Alan Burdick (Philadelphia, Pennsylvania); Robert C. Gorman (Lower Gwynedd, Pennsylvania); Joseph H. Gorman, III (Lower Gwynedd, Pennsylvania); Brendan Patrick Purcell (Philadelphia, Pennsylvania) |
ABSTRACT | The invention relates to compositions comprising (i) biocompatible hydrogel and (ii) one or more therapeutic agents contained within said hydrogel; wherein the hydrogel is cross-linked utilizing a cross-linker comprising a peptide sequence that is capable of being degraded by an enzyme; the therapeutic agent being effective as a treatment of a condition related to the presence of the enzyme. |
FILED | Friday, June 17, 2011 |
APPL NO | 13/805501 |
ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 38/10 (20130101) A61K 38/57 (20130101) A61K 38/1866 (20130101) A61K 47/24 (20130101) A61K 47/42 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694082 | Kaplan et al. |
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FUNDED BY |
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APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Tuna Yucel (Medford, Massachusetts); Tim Jia-Ching Lo (Medford, Massachusetts); Gary G. Leisk (Wilmington, Massachusetts) |
ABSTRACT | This invention provides for compositions, methods and devices for rapidly converting silk fibroin solution into a silk fibroin gel using direct application of voltage, in a process called electrogelation. The silk fibroin gel may be reversibly converted back to liquid form by applying reverse voltage or may be converted further to β-sheet structure by applying shear force or other treatments. The electrogelated silk may be used as an extracted bulk gel, spray or stream of gel for processing into materials or devices, or may be used as silk gel coating to devices. Active agents may be embedded in the silk gel for various medical applications. This invention also provides for methods and compositions for preparing adhesive silk pH-gels. For example, the method comprises reducing pH level of a silk fibroin solution to increase the bulk or local proton concentration of the silk fibroin solution, thereby forming adhesive silk gels. |
FILED | Tuesday, July 02, 2013 |
APPL NO | 13/933611 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 41/00 (20130101) A61K 47/42 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/0047 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/227 (20130101) A61L 27/3604 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/193 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694099 | Smith |
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FUNDED BY |
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APPLICANT(S) | FXS Ventures, LLC (Salem, New Hampshire) |
ASSIGNEE(S) | FXS VENTURES, LLC (Salem, New Hampshire) |
INVENTOR(S) | Francis X. Smith (Salem, New Hampshire) |
ABSTRACT | The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water. |
FILED | Thursday, January 14, 2016 |
APPL NO | 14/995400 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 33/12 (20130101) A01N 37/44 (20130101) A01N 43/38 (20130101) A01N 43/50 (20130101) A01N 47/44 (20130101) Purses; Luggage; Hand Carried Bags A45C 11/005 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/18 (20130101) A61L 12/12 (20130101) Original (OR) Class A61L 12/086 (20130101) A61L 12/143 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) C09D 7/1233 (20130101) Optical Elements, Systems, or Apparatus G02B 1/18 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694103 | Alferiev et al. |
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FUNDED BY |
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APPLICANT(S) | Ivan Alferiev (Clementon, New Jersey); Ilia Fishbein (Philadelphia, Pennsylvania); Michael Chorny (Philadelphia, Pennsylvania); Robert J. Levy (Merion Station, Pennsylvania); Benjamin Yellen (Durham, North Carolina); Darryl Williams (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
INVENTOR(S) | Ivan Alferiev (Clementon, New Jersey); Ilia Fishbein (Philadelphia, Pennsylvania); Michael Chorny (Philadelphia, Pennsylvania); Robert J. Levy (Merion Station, Pennsylvania); Benjamin Yellen (Durham, North Carolina); Darryl Williams (Philadelphia, Pennsylvania) |
ABSTRACT | A water-soluble photo-activatable polymer including: a photo-activatable group adapted to be activated by an irradiation source and to form a covalent bond between the water-soluble photo-activatable polymer and a matrix having at least one carbon; a reactive group adapted to covalently react with a biomaterial for subsequent delivery of the biomaterial to a cell; a hydrophilic group; and a polymer precursor. A composition including a monomolecular layer of the water-soluble photo-activatable polymer and a matrix having at least one carbon, wherein the monomolecular layer is covalently attached to the matrix by a covalent bond between the photo-activatable group and the at least one carbon. The composition further includes a biomaterial having a plurality of active groups, wherein the biomaterial is covalently attached to the monomolecular layer by covalent bonding between the active groups and reactive groups. Also provided is a method for delivery of a biomaterial to a cell. |
FILED | Friday, September 07, 2012 |
APPL NO | 13/606672 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/765 (20130101) A61K 31/785 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) Original (OR) Class A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 2400/18 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00637 (20130101) B01J 2219/00648 (20130101) Peptides C07K 17/02 (20130101) C07K 17/06 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/10 (20130101) C08F 8/10 (20130101) C08F 8/10 (20130101) C08F 8/10 (20130101) C08F 8/10 (20130101) C08F 8/10 (20130101) C08F 8/10 (20130101) C08F 8/32 (20130101) C08F 8/34 (20130101) C08F 8/34 (20130101) C08F 8/34 (20130101) C08F 8/34 (20130101) C08F 8/34 (20130101) C08F 120/06 (20130101) C08F 120/06 (20130101) C08F 126/02 (20130101) C08F 126/02 (20130101) C08F 126/02 (20130101) C08F 126/02 (20130101) C08F 126/02 (20130101) C08F 126/02 (20130101) C08F 226/02 (20130101) C08F 271/02 (20130101) C08F 290/00 (20130101) C08F 291/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/91 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/18 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694121 | Alexander et al. |
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FUNDED BY |
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APPLICANT(S) | CardioKinetix, Inc. (Menlo Park, California) |
ASSIGNEE(S) | CardioKinetix, Inc. (Menlo Park, California) |
INVENTOR(S) | Miles D. Alexander (Fremont, California); Matthew L. Pease (Mountain View, California); Barry L Templin (San Jose, California); Serjan D. Nikolic (San Francisco, California) |
ABSTRACT | A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function. |
FILED | Tuesday, February 25, 2014 |
APPL NO | 14/189856 |
ART UNIT | 3738 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 17/12022 (20130101) A61B 17/12122 (20130101) A61B 17/12172 (20130101) A61B 2017/00243 (20130101) A61B 2017/00575 (20130101) A61B 2017/00579 (20130101) A61B 2017/00592 (20130101) A61B 2017/00597 (20130101) A61B 2017/00615 (20130101) A61B 2017/00632 (20130101) A61B 2017/0649 (20130101) A61B 2017/00867 (20130101) A61B 2017/12095 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694180 | Cheung et al. |
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FUNDED BY |
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APPLICANT(S) | Dennis C. Cheung (San Gabriel, California); Jessy Dorn (Los Angeles, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Dennis C. Cheung (San Gabriel, California); Jessy Dorn (Los Angeles, California) |
ABSTRACT | A method of testing subjects' perception of complex shapes created by patterned multi-electrode direct stimulation of a retinal prosthesis is described. The complex shapes can be geometric shapes or characters such as letters of the alphabet and numbers. |
FILED | Friday, April 29, 2011 |
APPL NO | 13/097516 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/36046 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694181 | Bhadra et al. |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Niloy Bhadra (Cleveland Heights, Ohio); Narendra Bhadra (Chesterland, Ohio); Kevin L. Kilgore (Avon Lake, Ohio); Scott Lempka (Cleveland Heights, Ohio); Jesse Wainright (Willoughby Hills, Ohio); Tina Vrabec (Willoughby Hills, Ohio); Manfred Franke (Redwood City, California) |
ABSTRACT | Described herein are methods of treating various neurological disorders using electrical nerve conduction block (ENCB) without causing electrochemical damage. Examples of the various neurological disorders can include pain, muscle spasticity, hyperhidrosis, vertigo, sialorrhea, or the like. The methods can include placing an electrode contact in electrical communication with a nerve that transmits a signal related to the neurological disorder. The method also includes applying an ENCB to the nerve through the electrode contact. The electrode contact can include a high charge capacity material that prevents formation of damaging electrochemical reaction products at a charge delivered by the ENCB. The method also includes blocking transmission of the signal related to the neurological disorder through the nerve with the ENCB to treat the neurological disorder. |
FILED | Tuesday, December 15, 2015 |
APPL NO | 14/969826 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/06 (20130101) A61N 1/20 (20130101) A61N 1/0551 (20130101) A61N 1/3615 (20130101) A61N 1/36057 (20130101) A61N 1/36067 (20130101) A61N 1/36071 (20130101) Original (OR) Class A61N 1/36103 (20130101) A61N 1/36171 (20130101) A61N 1/37247 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694338 | Murphy et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | William Murphy (Waunakee, Wisconsin); Ngoc Nhi Le (Norcross, Georgia) |
ABSTRACT | Hydrogel arrays, methods for preparing hydrogel arrays and methods for screening cell-substrate interactions using the hydrogel arrays are disclosed. Advantageously, the hydrogel arrays include individual hydrogel posts that are completely isolatable, allowing for systematic and independent control of the chemical composition and physical dimensions of each hydrogel post. |
FILED | Thursday, December 18, 2014 |
APPL NO | 14/575084 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/0059 (20130101) B01J 2219/00315 (20130101) B01J 2219/00626 (20130101) B01J 2219/00637 (20130101) B01J 2219/00644 (20130101) B01J 2219/00659 (20130101) B01J 2219/00675 (20130101) B01J 2219/00711 (20130101) B01J 2219/00725 (20130101) B01J 2219/00736 (20130101) B01J 2219/00756 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5026 (20130101) G01N 33/5032 (20130101) G01N 33/5064 (20130101) G01N 33/5073 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694919 | Stokes |
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FUNDED BY |
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APPLICANT(S) | PHS Space Limited (Potters Bar, United Kingdom) |
ASSIGNEE(S) | PHS Space Limited (Hertfordshire, United Kingdom) |
INVENTOR(S) | Peter Hedley Stokes (Pitlochry, United Kingdom) |
ABSTRACT | The invention relates to the protection of spacecraft from debris and to de-orbiting devices of the atmospheric drag type, and to debris sweeping apparatus for the removal of debris from the space environment. The debris shielding apparatus for a spacecraft has a shield unit including a shielding surface for impeding incident debris. The shield unit is attached to the spacecraft body and has a drive mechanism for positioning the shield unit in relation to the spacecraft body. The drive mechanism is capable of moving the shield unit between a stowed first position and a deployed second position. In the deployed second position the plane of the shielding surface is at an angle to the spacecraft body. |
FILED | Thursday, January 28, 2016 |
APPL NO | 15/008723 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/52 (20130101) B64G 1/56 (20130101) Original (OR) Class B64G 1/222 (20130101) B64G 1/242 (20130101) B64G 1/1078 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695108 | Rosen et al. |
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FUNDED BY |
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APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
INVENTOR(S) | Eliot M. Rosen (Fairfax, Virginia); York A. Tomita (Bethesda, Maryland); Milton Brown (Brookeville, Maryland) |
ABSTRACT | The invention encompasses novel compounds and pharmaceutically acceptable salts thereof and compositions including therapeutically or prophylactically effective amounts of such compounds or pharmaceutically acceptable salts thereof. The invention also encompasses methods for treating or preventing diseases and disorders associated with abnormal cell growth, for example, treating or preventing cancer or tumor growth, which methods include administering to a mammal in need thereof a composition comprising a therapeutically or prophylactically effective amount of a compound of the invention or a pharmaceutically acceptable salt thereof. |
FILED | Friday, August 23, 2013 |
APPL NO | 14/423290 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 53/136 (20130101) C07C 57/40 (20130101) C07C 57/42 (20130101) C07C 57/50 (20130101) C07C 69/76 (20130101) C07C 69/92 (20130101) Original (OR) Class C07C 311/42 (20130101) C07C 2101/02 (20130101) C07C 2103/24 (20130101) C07C 2103/26 (20130101) Heterocyclic Compounds C07D 239/42 (20130101) C07D 249/04 (20130101) C07D 257/04 (20130101) C07D 307/33 (20130101) C07D 317/46 (20130101) C07D 317/58 (20130101) C07D 317/68 (20130101) C07D 401/14 (20130101) C07D 405/14 (20130101) C07D 409/14 (20130101) C07D 487/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695127 | Smithgall et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Thomas E. Smithgall (Wexford, Pennsylvania); Lori Ann Emert-Sedlak (Cranberry Township, Pennsylvania); Billy W. Day (Upper St. Clair, Pennsylvania); Jielu Zhao (Pittsburgh, Pennsylvania); Prema Chandrasekhar Iyer (Pittsburgh, Pennsylvania) |
ABSTRACT | Disclosed herein are embodiments of a compound capable of treating HIV. In particular disclosed embodiments, the compound is capable of inhibiting Nef, such as by acting as antagonists of HIV Nef function. Also disclosed are embodiments of a method of making the compound, embodiments of a method of using the compound, and embodiments of a method of identifying HIV Nef antagonists. The disclosed compound may be used alone or in combination with other pharmacologically active agents in order to promote reducing drug resistance and/or cumulative toxicity. |
FILED | Wednesday, November 06, 2013 |
APPL NO | 14/441475 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) A61K 31/415 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/429 (20130101) A61K 31/429 (20130101) A61K 31/655 (20130101) A61K 31/4155 (20130101) A61K 31/4155 (20130101) A61K 31/4178 (20130101) A61K 31/4178 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) A61K 31/5377 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 231/20 (20130101) C07D 231/46 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 403/04 (20130101) C07D 405/04 (20130101) C07D 417/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695133 | Stockwell et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Brent R Stockwell (New York, New York); Matthew Welsch (New York, New York); Wan Seok Yang (New York, New York) |
ABSTRACT | The present invention provides, inter alia, compounds having the structure (1) compositions containing such compounds are also provided. Methods for using such compounds or compositions for treating or ameliorating the effects of a cancer having a cell that harbors an oncogenic RAS mutation, for modulating a lipoxygenase in a ferroptosis cell death pathway, and for depleting reduced glutathione (GSH) in a cell harboring an oncogenic RAS mutation are further provided. |
FILED | Friday, July 12, 2013 |
APPL NO | 14/414669 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 213/61 (20130101) C07D 239/91 (20130101) Original (OR) Class C07D 403/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695153 | Arora et al. |
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FUNDED BY |
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APPLICANT(S) | New York University (New York, New York); The Ohio State University Research Foundation (Columbus, Ohio); The Regents of the University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | New York University (New York, New York); The Ohio State University Research Foundation (Columbus, Ohio); The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Paramjit S. Arora (Cold Spring Harbor, New York); Quintin Pan (Dublin, Ohio); Anna Mapp (Ann Arbor, Michigan) |
ABSTRACT | The present invention relates to oligooxopiperazines for reactivating p53. The oligooxopiperazines comprise two or three oxopiperazine rings and substantially mimic helix αB of the C-terminal transactivation domain of Hypoxia-Inducible Factor 1α. Methods of using the oligooxopiperazines are also disclosed. Exemplary oligooxopiperazines include those of Formula I below (wherein A, R1, R2, R3, R4, and B are as defined herein). |
FILED | Tuesday, January 21, 2014 |
APPL NO | 14/160037 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 403/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695156 | Atwood et al. |
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FUNDED BY |
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APPLICANT(S) | Brown University (Providence, Rhode Island) |
ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
INVENTOR(S) | Walter Atwood (Rumford, Rhode Island); Christian Nelson (Branford, Connecticut); Jason K. Sello (Providence, Rhode Island); Daniel William Carney (San Diego, California) |
ABSTRACT | Provided herein are compounds of Formula (I) or (II): (I) (II) pharmaceutically acceptable salts, tautomers, prodrugs, and stereoisomers thereof, and pharmaceutical compositions thereof, wherein X, RN, R1, R3, R4, p, and m are as defined herein. Such compounds and compositions have been found useful in the treatment or prevention of viral infections, e.g., polyomaviral infections, and are further envisioned useful in treatment or prevention of other pathogenic conditions associated with endosomal trafficking. Methods of treating or preventing an infection by a pathogen secreting an AB5 toxin is also contemplated. |
FILED | Monday, July 15, 2013 |
APPL NO | 14/415177 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Heterocyclic Compounds C07D 403/04 (20130101) C07D 405/04 (20130101) C07D 409/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695193 | Akabas et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); ALBERT EINSTEIN COLLEGE OF MEDICINE INC. (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York) |
INVENTOR(S) | Myles Akabas (Scarsdale, New York); Ithiel James Frame (Bronx, New York); Donald W. Landry (New York, New York); Roman Deniskin (Bronx, New York); Shixian Deng (White Plains, New York); Alison Rinderspacher (Bronx, New York) |
ABSTRACT | Inhibitors of Plasmodium falciparum equilibrative nucleoside transporter type 1 are identified and methods of use as anti-parasitic compounds are provided. |
FILED | Thursday, June 26, 2014 |
APPL NO | 14/898846 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Heterocyclic Compounds C07D 209/12 (20130101) C07D 239/88 (20130101) C07D 311/16 (20130101) C07D 403/12 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) C07D 498/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695224 | Walensky et al. |
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FUNDED BY |
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APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Loren D. Walensky (Newton, Massachusetts); Gregory Bird (Pelham, New Hampshire) |
ABSTRACT | The present invention provides stably crosslinked insulinotropic polypeptides having superior and unexpected benefits in the treatment of conditions involving abnormal glucose homeostasis, e.g., type 2 diabetes and conditions relating to type 2 diabetes. Such benefits include, but are not limited to, extended polypeptide half-life, enhanced alpha-helicity, improved thermal stability and protease resistance, increased functional activity and pharmacologic properties, improved bioavailability when administered by any route, and improved bioavailability and gastrointestinal absorption when delivered orally, as compared to the corresponding unmodified polypeptides. The invention also provides compositions for administering the polypeptides of the invention, as well as methods for preparing and evaluating the polypeptides of the invention. |
FILED | Tuesday, February 09, 2016 |
APPL NO | 15/019678 |
ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/575 (20130101) C07K 14/605 (20130101) Original (OR) Class C07K 14/57563 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695230 | Kwong et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Peter D. Kwong (Washington, District of Columbia); Gary J. Nabel (Cambridge, Massachusetts); Rebecca S. Rudicell (Silver Springs, Maryland); John Mascola (Rockville, Maryland); Mark Connors (Bethesda, Maryland); Ivelin Georgiev (Gaithersburg, Maryland); Jiang Zhu (Ashburn, Virginia); Young Do Kwon (Rockville, Maryland); Tongqing Zhou (Boyds, Maryland); Yongping Yang (Potomac, Maryland); Baoshan Zhang (Bethesda, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Xueling Wu (Potomac, Maryland); Zhi-yong Yang (Potomac, Maryland); Wei Shi (Rockville, Maryland) |
ABSTRACT | Monoclonal neutralizing antibodies that specifically bind to HIV-1 gp120 and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV infection is disclosed. |
FILED | Monday, December 10, 2012 |
APPL NO | 14/363740 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/41 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 33/56988 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695246 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Yong-Jun Liu (Pearland, Texas); Kui Shin Voo (Pearland, Texas); Laura Bover (Pearland, Texas); Naoya Tsurushita (Palo Alto, California); J. Yun Tso (Menlo Park, California); Shankar Kumar (Pleasanton, California) |
ABSTRACT | Human antibodies, preferably recombinant human antibodies, both humanized and chimeric, which specifically bind to human OX40 are disclosed. Preferred antibodies have high affinity for OX40 receptor and activate the receptor in vitro and in vivo. The antibody can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, are useful for modulating receptor activity, e.g., in a human subject suffering from a disorder in which OX40 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies are provided, and methods of synthesizing the recombinant human antibodies, are also provided. |
FILED | Monday, April 13, 2015 |
APPL NO | 14/684550 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2878 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/56 (20130101) C07K 2317/74 (20130101) C07K 2317/75 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695251 | Tsien et al. |
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FUNDED BY |
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APPLICANT(S) | Roger Y. Tsien (La Jolla, California); Tao Jiang (San Diego, California); Elamprakash N. Savariar (San Diego, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Roger Y. Tsien (La Jolla, California); Tao Jiang (San Diego, California); Elamprakash N. Savariar (San Diego, California) |
ABSTRACT | The invention provides compositions useful as molecular probes. In particular, the invention provides activatable cell penetrating peptides comprising a fluorescence donor and a fluorescence acceptor. Exemplary fluorescence donors and fluorescence acceptors include compounds derived from cyanine. Also provided are ratiometric, multispectral, and excitation lifetime imaging methods for detecting the molecular probes provided herein. |
FILED | Friday, August 03, 2012 |
APPL NO | 13/566913 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0095 (20130101) A61K 47/48246 (20130101) A61K 47/48315 (20130101) A61K 47/48338 (20130101) A61K 49/00 (20130101) A61K 49/14 (20130101) A61K 49/0032 (20130101) A61K 49/0043 (20130101) A61K 49/0056 (20130101) A61K 49/085 (20130101) A61K 49/146 (20130101) A61K 51/088 (20130101) Peptides C07K 14/4728 (20130101) C07K 19/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695252 | Greene et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Mark I. Greene (Penn Valley, Pennsylvania); Hongtao Zhang (Paoli, Pennsylvania); Xiaomin Song (Drexel Hill, Pennsylvania); Ramachandran Murali (Beverly Hills, California); Masahide Tone (Los Angeles, California) |
ABSTRACT | Disclosed herein are recombinant protein scaffolds and recombinant multifunctional protein scaffolds for use in producing antigen-binding proteins In addition, nucleic acids encoding such recombinant protein scaffolds, recombinant multifunctional protein scaffolds, and antigen-binding proteins are provided Vectors and cells useful for expression of the described proteins are also provided, as are methods of use. |
FILED | Wednesday, April 02, 2014 |
APPL NO | 14/243614 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) A61K 49/00 (20130101) Peptides C07K 14/70596 (20130101) C07K 16/2896 (20130101) C07K 19/00 (20130101) Original (OR) Class C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695262 | Mohapatra et al. |
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APPLICANT(S) | Subhra Mohapatra (Lutz, Florida); Chunyan Wang (Tampa, Florida) |
ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
INVENTOR(S) | Subhra Mohapatra (Lutz, Florida); Chunyan Wang (Tampa, Florida) |
ABSTRACT | The present invention concerns molecularly imprinted polymers (MIPs) having an affinity for natriuretic peptides, such as atrial natriuretic peptide (ANP). In some embodiments, the MIP is a nanoparticle (a molecularly imprinted polymeric nanoparticle (MIPNP)). Other aspects of the invention include methods of preparing an MIP having affinity for a natriuretic peptide, methods for binding a natriuretic peptide in vitro or in vivo using an MIP of the invention, methods for interfering with the binding of a natriuretic peptide with its receptor in vivo, methods for reducing inflammation, cell growth, cell differentiation, or a cell proliferation disorder, methods for detecting natriuretic peptides, and devices and kits for sequestering and/or detecting natriuretic peptides. |
FILED | Friday, February 24, 2012 |
APPL NO | 14/000326 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 14/58 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/06 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 2333/58 (20130101) G01N 2600/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24802 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695399 | Woodruff et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Teresa K. Woodruff (Chicago, Illinois); Ji-Yong Julie Kim (Elmhurst, Illinois); Joanna E. Burdette (Chicago, Illinois); Spiro Getsios (Chicago, Illinois); Sevim Yildiz Arslan (Chicago, Illinois); Shuo Xiao (Chicago, Illinois); Jie Zhu (Chicago, Illinois) |
ABSTRACT | The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system. |
FILED | Wednesday, January 28, 2015 |
APPL NO | 14/607862 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0682 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/31 (20130101) C12N 2502/243 (20130101) C12N 2513/00 (20130101) C12N 2533/74 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695400 | Yan et al. |
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FUNDED BY |
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APPLICANT(S) | Hai Yan (Chapel Hill, North Carolina); Darell Bigner (Mebane, North Carolina); Genglin Jin (Chapel Hill, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Hai Yan (Chapel Hill, North Carolina); Darell Bigner (Mebane, North Carolina); Genglin Jin (Chapel Hill, North Carolina) |
ABSTRACT | We provide IDH1 gene-defective cell lines (e.g., IDH1R132H heterozygous and IDH1R132H homozygous) derived from dissociated human astrocytoma samples. The cells can be used alone or in combination with each other or other cell types as a tool for determining the impact of IDH1R132H on cellular biology, tumorigenesis, and metabolic profiles. The cell lines may be used to test and identify therapeutic targets and to screen for molecular therapeutic agents. |
FILED | Monday, October 24, 2011 |
APPL NO | 13/878596 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695425 | Rossi et al. |
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FUNDED BY |
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APPLICANT(S) | CITY OF HOPE (Duarte, California) |
ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
INVENTOR(S) | John Rossi (Duarte, California); Katrin Tiemann (Pasadena, California); Jiehua Zhou (Monrovia, California); Britta Vallazza (Hagen, Germany) |
ABSTRACT | In one embodiment, a B cell specific aptamer-siRNA chimera is provided. The B cell specific aptamer-siRNA chimera may include an RNA aptamer that binds BAFF-R and an siRNA molecule conjugated to the RNA aptamer via a nucleotide linker. In another embodiment, a B cell specific RNA aptamer is provided. The RNA aptamer may be a molecule that binds to BAFF-R that has the sequence SEQ ID NO:37, SEQ ID NO:38 or SEQ ID NO:39. In some embodiments, the RNA aptamer is conjugated, via a nucleotide linker, to an siRNA molecule that suppresses expression of one or more target oncogenes in one or more B cells. In one aspect, the one or more target oncogenes are selected from Bcl6, Bcl2, STAT3, Cyclin D1, Cyclin E2 and c-myc. In another embodiment, methods for treating a B cell malignancy in a cancer patient are provided. Such methods may include administering a therapeutically effective amount of a therapeutic composition, the therapeutic composition comprising a B cell specific RNA aptamer that binds BAFF-R. |
FILED | Friday, May 27, 2016 |
APPL NO | 15/166793 |
ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 47/48092 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/115 (20130101) Original (OR) Class C12N 15/1135 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/51 (20130101) C12N 2310/3519 (20130101) C12N 2320/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695427 | DeAngelis et al. |
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FUNDED BY |
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APPLICANT(S) | Paul L. DeAngelis (Edmond, Oklahoma); Nigel J. Otto (Okarche, Oklahoma) |
ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
INVENTOR(S) | Paul L. DeAngelis (Edmond, Oklahoma); Nigel J. Otto (Okarche, Oklahoma) |
ABSTRACT | Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-α1,4-D-GlcNAc-α1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes UDP-GlcUA and UDP-GlcNAc to synthesize a polysaccharide having the structure [-4-D-GlcUA-α1,4-D-GlcNAc-α1-]n. |
FILED | Tuesday, January 31, 2012 |
APPL NO | 13/981886 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 37/0063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1051 (20130101) C12N 15/52 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) C12P 19/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695479 | Vogelstein et al. |
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FUNDED BY |
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APPLICANT(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Donald Williams Parsons (Ellicott City, Maryland); Rebecca J. Leary (Baltimore, Maryland); Meng Li (Baltimore, Maryland); Xiaosong Zhang (Baltimore, Maryland); Sian Jones (Baltimore, Maryland); Gregory J. Riggins (Baltimore, Maryland); Victor Velculescu (Dayton, Maryland); Darell Bigner (Mebane, North Carolina); Hai Yan (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Duke University (Durham, North Carolina) |
INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Donald Williams Parsons (Ellicott City, Maryland); Rebecca J. Leary (Baltimore, Maryland); Meng Li (Baltimore, Maryland); Xiaosong Zhang (Baltimore, Maryland); Sian Jones (Baltimore, Maryland); Gregory J. Riggins (Baltimore, Maryland); Victor Velculescu (Dayton, Maryland); Darell Bigner (Mebane, North Carolina); Hai Yan (Chapel Hill, North Carolina) |
ABSTRACT | Medulloblastoma (MB) is the most common malignant brain tumor of children. To identify the genetic alterations in this tumor type, we searched for copy number alterations using high density microarrays and sequenced all known protein-coding genes and miRNA genes using Sanger sequencing. We found that, on average, each tumor had 11 gene alterations, markedly fewer than in common adult cancers. In addition to alterations in the Hedgehog and Wnt pathways, our analysis led to the discovery of genes not previously known to be altered in MBs. Most notably, inactivating mutations of the histone H3K4 trimethylase genes MLL2 or MLL3 were identified in 16% of MB patients. These results demonstrate key differences between the genetic landscapes of adult and childhood cancers, highlight dysregulation of developmental pathways as an important mechanism underlying MBs, and identify a role for a specific type of histone methylation in human tumorigenesis. |
FILED | Tuesday, November 08, 2011 |
APPL NO | 13/884154 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696228 | Tarler |
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FUNDED BY |
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APPLICANT(S) | Matthew D. Tarler (Avon, Ohio) |
ASSIGNEE(S) | Great Lakes Neurotechnologies Inc. (Cleveland, Ohio) |
INVENTOR(S) | Matthew D. Tarler (Avon, Ohio) |
ABSTRACT | The present invention is related to a sensor for simultaneously measuring both normal and shear forces applied to the sensor, and further a statically responsive sensor for measuring shear forces. The present invention further includes a method of designing an object or a device using these sensors. |
FILED | Thursday, July 07, 2016 |
APPL NO | 15/204284 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Characteristic Features of Footwear; Parts of Footwear A43B 3/0005 (20130101) A43B 5/00 (20130101) Machines, Tools, Equipment or Methods for Manufacturing or Repairing Footwear A43D 1/02 (20130101) Diagnosis; Surgery; Identification A61B 5/0024 (20130101) A61B 5/1038 (20130101) A61B 5/6807 (20130101) A61B 2503/10 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 2230/60 (20130101) A63B 2243/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/16 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696275 | Gillis et al. |
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FUNDED BY |
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APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
INVENTOR(S) | Kevin Gillis (Columbia, Missouri); Jia Yao (Columbia, Missouri) |
ABSTRACT | Methods and apparati for performing measurements of electrical signals in a multi-compartmented fluidic array format where the signal to noise ratio is improved are disclosed. |
FILED | Friday, October 11, 2013 |
APPL NO | 14/052394 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/27 (20130101) G01N 27/417 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696296 | Ramakrishnan et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Parameswaran Ramakrishnan (Pasadena, California); David Baltimore (Pasadena, California) |
ABSTRACT | Serine 350 has been identified as the site of O-GlycNAcylation of c-Rel. Methods are provided for identifying compositions capable of blocking c-Rel activation. The methods generally involve identifying compounds that inhibit O-GlcNAcylation of c-Rel at the serine 350 residue, thereby preventing c-Rel activation and production of c-Rel-dependent cytokines. |
FILED | Tuesday, January 28, 2014 |
APPL NO | 14/166681 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) A61K 31/655 (20130101) A61K 31/7028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) Original (OR) Class G01N 2440/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696297 | Marchetto et al. |
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FUNDED BY |
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APPLICANT(S) | Maria C. N. Marchetto (La Jolla, California); Fred H. Gage (La Jolla, California); Alysson R. Muotri (La Jolla, California) |
ASSIGNEE(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
INVENTOR(S) | Maria C. N. Marchetto (La Jolla, California); Fred H. Gage (La Jolla, California); Alysson R. Muotri (La Jolla, California) |
ABSTRACT | Provided herein are methods and compositions useful in treating neurological disorders. |
FILED | Thursday, December 23, 2010 |
APPL NO | 13/518842 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) Original (OR) Class G01N 2800/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696305 | Pratt et al. |
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FUNDED BY |
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APPLICANT(S) | Puget Sound Blood Center (Seattle, Washington) |
ASSIGNEE(S) | Bloodworks (Seattle, Washington) |
INVENTOR(S) | Kathleen Pratt (Bethesda, Maryland); Kenneth B. Lewis (Seattle, Washington) |
ABSTRACT | Disclosed herein are methods, systems, mediums, and kits for use in phenotyping antibody responses via devices such as surface plasmon resonance devices. Such phenotypes can include total target-specific antibody titers, quantitative isotype distribution of the target-specific antibodies, and/or epitope specificity of the target-specific antibodies. Other methods, systems, mediums, and kits are also disclosed. |
FILED | Wednesday, October 31, 2012 |
APPL NO | 14/354476 |
ART UNIT | 1678 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/564 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696306 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Tae-Wan Kim (East Brunswick, New Jersey); Laura Beth Johnson McIntire (Long Island City, New York); Natalie Landman (New York, New York); Gina Finan (Brooklyn, New York) |
ABSTRACT | Successful CNS drug discovery requires a scalable, highly physiological neuronal model. Using directed differentiation of mouse embryonic stem (mES) cells, including mES cells isolated from a mouse model of Alzheimer's disease (AD), a highly homogeneous primary neuronal model amenable to phenotypic assays for production and synaptotoxicity of amyloid β-peptide was developed. This model furnishes a highly physiological and AD-relevant platform suitable for high throughput small molecule and functional genetic screens, providing specific small molecule compounds identified by such screens. |
FILED | Friday, September 06, 2013 |
APPL NO | 14/020776 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/01 (20130101) A61K 31/03 (20130101) A61K 31/15 (20130101) A61K 31/41 (20130101) A61K 31/085 (20130101) A61K 31/137 (20130101) A61K 31/145 (20130101) A61K 31/473 (20130101) A61K 31/5375 (20130101) A61K 31/7048 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 2501/385 (20130101) C12N 2506/02 (20130101) C12N 2533/50 (20130101) C12N 2533/52 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 33/56966 (20130101) Original (OR) Class G01N 2800/2821 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696313 | Santagata et al. |
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APPLICANT(S) | WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Sandro Santagata (Jamaica Plain, Massachusetts); Susan Lindquist (Chestnut Hill, Massachusetts); Luke J. Whitesell (Somerville, Massachusetts); Tan A. Ince (Miami, Florida) |
ABSTRACT | In some aspects, the invention relates to Heat Shock Protein-1 (HSF1) gene and HSF1 gene products. In some aspects, the invention provides methods of tumor diagnosis, prognosis, treatment-specific prediction, or treatment selection, the methods comprising assessing the level of HSF1 expression or HSF1 activation in a sample obtained from the tumor. In some aspects, the invention relates to the discovery that increased HSF1 expression and increased HSF1 activation correlate with poor outcome in cancer, e.g., breast cancer. |
FILED | Friday, October 05, 2012 |
APPL NO | 14/350328 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 33/57496 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696323 | Brasier et al. |
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FUNDED BY |
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APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Allan Brasier (Galveston, Texas); John E. Wiktorowicz (League City, Texas); Hyunsu Ju (League City, Texas); Nisha Jain Garg (League City, Texas) |
ABSTRACT | Certain embodiments include methods for assessing a subject having a trypanosome infection for the presence or absence of indications of cardiomyopathy. |
FILED | Thursday, September 10, 2015 |
APPL NO | 14/850113 |
ART UNIT | 1678 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 33/56905 (20130101) G01N 2800/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696534 | Shroff et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INTITUTES OF HEALTH (Washington, District of Columbia); Hari Shroff (Washington, District of Columbia); Andrew York (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Hari Shroff (Washington, District of Columbia); Andrew York (Bethesda, Maryland) |
ABSTRACT | A multi-focal selective illumination microscopy (SIM) system for generating multi-focal patterns of a sample is disclosed. The multi-focal SIM system performs a focusing, scaling and summing operation on each multi-focal pattern in a sequence of multi-focal patterns that completely scan the sample to produce a high resolution composite image. |
FILED | Friday, February 22, 2013 |
APPL NO | 14/380392 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 2021/6478 (20130101) G01N 2201/0633 (20130101) Optical Elements, Systems, or Apparatus G02B 21/004 (20130101) G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/0072 (20130101) Original (OR) Class G02B 21/0076 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696535 | Prakash et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
INVENTOR(S) | Manu Prakash (San Francisco, California); James Stanley Cybulski (Palo Alto, California); James C. Clements (Everett, Washington) |
ABSTRACT | An optical device, such as a microscope, is disclosed that can be assembled from flat materials. The optical device can be assembled via a series of folds of a flat material. The optical microscope can include a stage for supporting a sample, an optic stage, and a light source. The optic stage can include one or more lenses. The optical microscope can be capable of obtaining simultaneous images from different forms of microscopy. The optical microscope may have bright field and filter field viewing capabilities wherein a user shifts from bright field to filter field by lateral movement of the stage containing a lens and a light source that cooperate to provide either the bright field or the filter field. |
FILED | Monday, February 11, 2013 |
APPL NO | 14/376010 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 21/0008 (20130101) G02B 21/26 (20130101) G02B 21/0076 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696729 | Ismagilov et al. |
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FUNDED BY |
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APPLICANT(S) | University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Rustem F. Ismagilov (Chicago, Illinois); Bo Zheng (Chicago, Illinois); Cory John Gerdts (Chicago, Illinois) |
ABSTRACT | The present invention provides microfluidic technology enabling rapid and economical manipulation of reactions on the femtoliter to microliter scale. |
FILED | Tuesday, December 22, 2015 |
APPL NO | 14/978341 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/0471 (20130101) B01F 13/0071 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/0059 (20130101) B01J 2219/00522 (20130101) B01J 2219/00585 (20130101) B01J 2219/00599 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0293 (20130101) B01L 3/502746 (20130101) B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) B01L 2300/0838 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 35/08 (20130101) G01N 2035/1034 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0694 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696897 | Garcia |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Maurice Garcia (San Francisco, California) |
ABSTRACT | Provided are methods, systems, devices, and computer programs enabling the measurement of various objects using imaging. The inventions are adaptable to mobile devices such as smartphones, allowing a range of unique measurements to be conveniently made, including length, area, distance, velocity, and height. The methods, systems, devices, and computer programs include the novel application of image-based measurement in medical, research, and other contexts. |
FILED | Friday, October 19, 2012 |
APPL NO | 14/352943 |
ART UNIT | 2485 — Recording and Compression |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/02 (20130101) G01B 11/022 (20130101) Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/0487 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/62 (20170101) G06T 2207/10004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698001 | Coon et al. |
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FUNDED BY |
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APPLICANT(S) | Joshua J. Coon (Middleton, Wisconsin); Michael S. Westphall (Fitchburg, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Joshua J. Coon (Middleton, Wisconsin); Michael S. Westphall (Fitchburg, Wisconsin) |
ABSTRACT | Described herein are mass spectrometry systems and methods which improve the accuracy of isobaric tag-based quantification by alleviating the pervasive problem of precursor interference and co-isolation of impurities through gas-phase purification. During the gas-phase purification, the mass-to-charge ratios of precursor ions within at least a selected range are selectively changed allowing ions having similar unmodified mass-to-charge ratios to be separated before further isolation, fragmentation or analysis. |
FILED | Tuesday, April 03, 2012 |
APPL NO | 13/438209 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/483 (20130101) G01N 33/6848 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/26 (20130101) Original (OR) Class H01J 49/0072 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/24 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 09694035 | Aggarwal et al. |
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FUNDED BY |
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APPLICANT(S) | Mesoblast International Sárl (Meyrin, Switzerland) |
ASSIGNEE(S) | MESOBLAST INTERNATIONAL SARL (Meyrin, Switzerland) |
INVENTOR(S) | Sudeepta Aggarwal (North Potomac, Maryland); Mark F. Pittenger (Severna Park, Maryland); Timothy Varney (Baltimore, Maryland) |
ABSTRACT | Methods of treating autoimmune diseases, allergic responses, cancer, or inflammatory diseases in an animal, promoting wound healing, repairing epithelial damage and promoting angiogenesis in an organ or tissue of an animal by administering to the animal mesenchymal stem cells in an effective amount. |
FILED | Thursday, July 17, 2014 |
APPL NO | 14/334128 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 38/2026 (20130101) A61K 38/2066 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) C12N 5/0663 (20130101) C12N 5/0664 (20130101) C12N 5/0665 (20130101) C12N 5/0666 (20130101) C12N 5/0667 (20130101) C12N 5/0668 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694062 | Aguiar et al. |
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FUNDED BY |
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APPLICANT(S) | Joao Aguiar (Rockville, Maryland); Keith Limbach (Gaithersburg, Maryland); Martha Sedegah (Gaithersburg, Maryland); Thomas Richie (Glenelg, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Joao Aguiar (Rockville, Maryland); Keith Limbach (Gaithersburg, Maryland); Martha Sedegah (Gaithersburg, Maryland); Thomas Richie (Glenelg, Maryland) |
ABSTRACT | The invention provides novel malaria polypeptides expressed at the pre-erythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation. |
FILED | Wednesday, March 19, 2014 |
APPL NO | 14/219390 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/545 (20130101) Peptides C07K 14/445 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2799/04 (20130101) C12N 2799/023 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694072 | North |
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FUNDED BY |
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APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
INVENTOR(S) | William G. North (Hanover, New Hampshire) |
ABSTRACT | The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2. Methods for preventing and treating neuroendocrine cancers are also disclosed. |
FILED | Monday, October 27, 2014 |
APPL NO | 14/524483 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) A61K 31/439 (20130101) A61K 33/06 (20130101) A61K 39/39558 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/286 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 2333/70571 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694082 | Kaplan et al. |
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FUNDED BY |
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APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Tuna Yucel (Medford, Massachusetts); Tim Jia-Ching Lo (Medford, Massachusetts); Gary G. Leisk (Wilmington, Massachusetts) |
ABSTRACT | This invention provides for compositions, methods and devices for rapidly converting silk fibroin solution into a silk fibroin gel using direct application of voltage, in a process called electrogelation. The silk fibroin gel may be reversibly converted back to liquid form by applying reverse voltage or may be converted further to β-sheet structure by applying shear force or other treatments. The electrogelated silk may be used as an extracted bulk gel, spray or stream of gel for processing into materials or devices, or may be used as silk gel coating to devices. Active agents may be embedded in the silk gel for various medical applications. This invention also provides for methods and compositions for preparing adhesive silk pH-gels. For example, the method comprises reducing pH level of a silk fibroin solution to increase the bulk or local proton concentration of the silk fibroin solution, thereby forming adhesive silk gels. |
FILED | Tuesday, July 02, 2013 |
APPL NO | 13/933611 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 41/00 (20130101) A61K 47/42 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/0047 (20130101) A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/227 (20130101) A61L 27/3604 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/193 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694388 | Curran et al. |
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FUNDED BY |
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APPLICANT(S) | Seamus Curran (Pearland, Texas); Kang-Shyang Liao (Houston, Texas); Nigel Alley (Houston, Texas); Amrita Haldar (Houston, Texas); Alexander Wang (Houston, Texas); Renat Tatarin (Houston, Texas) |
ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
INVENTOR(S) | Seamus Curran (Pearland, Texas); Kang-Shyang Liao (Houston, Texas); Nigel Alley (Houston, Texas); Amrita Haldar (Houston, Texas); Alexander Wang (Houston, Texas); Renat Tatarin (Houston, Texas) |
ABSTRACT | A process of fabricating the waterproof coating may include selecting a substrate, utilizing a sol-gel comprising a silane or silane derivative and metal oxide precursor to coat the substrate, and optionally coating the substrate with a hydrophobic chemical agent and/or other chemical agents to create a surface with nanoscopic or microscopic features. The process may utilize an all solution process or controlled environment for fabricating self-cleaning and waterproof coating that prevent wetting or staining of a substrate, or may utilize a controlled environment. |
FILED | Wednesday, May 14, 2014 |
APPL NO | 14/277325 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/185 (20130101) B05D 5/083 (20130101) Original (OR) Class B05D 2350/60 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 23/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694440 | Moor et al. |
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FUNDED BY |
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APPLICANT(S) | James J. Moor (New Hartford, Connecticut); Herbert A. Chin (Portland, Connecticut); Greg Czeladko (Avon, Connecticut); Gene A. Danko (Manchester, Connecticut); Andrew L. Haynes (Glastonbury, Connecticut); Wangen Lin (S. Glastonbury, Connecticut); Vincent Nevins (Chester, Connecticut); Robert P. Schaefer (Vernon Rockville, Connecticut); Eberhardt Privitzer (Los Lunas, New Mexico) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | James J. Moor (New Hartford, Connecticut); Herbert A. Chin (Portland, Connecticut); Greg Czeladko (Avon, Connecticut); Gene A. Danko (Manchester, Connecticut); Andrew L. Haynes (Glastonbury, Connecticut); Wangen Lin (S. Glastonbury, Connecticut); Vincent Nevins (Chester, Connecticut); Robert P. Schaefer (Vernon Rockville, Connecticut); Eberhardt Privitzer (Los Lunas, New Mexico) |
ABSTRACT | An example method of attaching an airfoil for an integrally bladed rotor includes placing a support collar in an installed position around at least a leading edge and trailing edge of an airfoil stub to be repaired in an integrally bladed rotor. The support collar and the airfoil stub together have a midline that is positioned between opposing, laterally outer surfaces of the airfoil stub when the support collar is in the installed position. The method performs linear friction welding to add a replacement airfoil to the airfoil stub. |
FILED | Friday, October 22, 2010 |
APPL NO | 12/909928 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/1205 (20130101) Original (OR) Class B23K 2201/001 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/34 (20130101) F01D 5/3061 (20130101) F01D 25/285 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/80 (20130101) F05D 2230/239 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49321 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694917 | Chao et al. |
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FUNDED BY |
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APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
INVENTOR(S) | Chia-Chun Chao (Rolling Hills Estates, California); Brian E. Kirkpatrick (El Segundo, California); Victor Shiaw-Jong Lin (Oak Park, California); Siegfried W. Janson (Redondo Beach, California) |
ABSTRACT | A deployment algorithm that populate a group of companion satellites around a center satellite, and a control algorithm for maintaining the companion satellites in close formation around the center satellite. |
FILED | Wednesday, June 15, 2016 |
APPL NO | 15/183384 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/26 (20130101) B64G 1/242 (20130101) B64G 1/405 (20130101) B64G 1/1085 (20130101) Original (OR) Class B64G 3/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695051 | Strobel et al. |
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FUNDED BY |
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APPLICANT(S) | CARNEGIE INSTITUTION OF WASHINGTON (Washington, District of Columbia) |
ASSIGNEE(S) | CARNEGIE INSTITUTION OF WASHINGTON (Washington, District of Columbia) |
INVENTOR(S) | Timothy A. Strobel (Washington, District of Columbia); Duck Young Kim (Washington, District of Columbia); Oleksandr O. Kurakevych (Washington, District of Columbia) |
ABSTRACT | The invention relates to a new phase of silicon, Si24, and a method of making the same. Si24 has a quasi-direct band gap, with a direct gap value of 1.34 eV and an indirect gap value of 1.3 eV. The invention also relates to a compound of the formula Na4Si24 and a method of making the same. Na4Si24 may be used as a precursor to make Si24. |
FILED | Tuesday, July 08, 2014 |
APPL NO | 14/903131 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/00 (20130101) C01B 33/02 (20130101) Original (OR) Class C01B 33/06 (20130101) C01B 33/021 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695177 | Sherrill et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | William Matthew Sherrill (Aberdeen, Maryland); Eric Christopher Johnson (Millington, Maryland) |
ABSTRACT | An improved method of preparing tetranitroglycoluril (TNGU) via the in situ decomposition of a nitrimino group with elimination of nitrogen without the use of dinitrogen pentoxide. The compound is useful as a high energy, high density explosive or propellant oxidizer. |
FILED | Monday, September 29, 2014 |
APPL NO | 14/499278 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 25/34 (20130101) C06B 45/00 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695203 | Iacono et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Scott Iacono (Colorado Springs, Colorado); Abby Rose Jennings (Colorado Springs, Colorado) |
ABSTRACT | Fluorinated cyclopentene moieties and fluorinated cyclopentene functionalized silica materials are provided. The fluorinated cyclopentene functionalized silica materials include a silica material having the fluorinated cyclopentene moiety covalently bonded thereto. Exemplary silica materials include a polysilsesquioxane, a nanosilica, a microsilica, a silica gel, a silica aerogel, or combinations thereof. The fluorinated cyclopentene moieties are based on a modification of perfluorocyclopentene (i.e., 1,2,3,3,4,4,5,5-octafluoro-1-cyclopentene) by nucleophilic substitution with an appropriate nucleophile having a reactive functional group. Methods for preparing fluorinated cyclopentene moieties and the corresponding fluorinated cyclopentene functionalized silica materials are also provided. |
FILED | Friday, March 18, 2016 |
APPL NO | 15/074128 |
ART UNIT | 1671 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 43/192 (20130101) C07C 43/247 (20130101) C07C 323/17 (20130101) C07C 2101/10 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/12 (20130101) C07F 7/21 (20130101) Original (OR) Class C07F 7/1836 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695251 | Tsien et al. |
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FUNDED BY |
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APPLICANT(S) | Roger Y. Tsien (La Jolla, California); Tao Jiang (San Diego, California); Elamprakash N. Savariar (San Diego, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Roger Y. Tsien (La Jolla, California); Tao Jiang (San Diego, California); Elamprakash N. Savariar (San Diego, California) |
ABSTRACT | The invention provides compositions useful as molecular probes. In particular, the invention provides activatable cell penetrating peptides comprising a fluorescence donor and a fluorescence acceptor. Exemplary fluorescence donors and fluorescence acceptors include compounds derived from cyanine. Also provided are ratiometric, multispectral, and excitation lifetime imaging methods for detecting the molecular probes provided herein. |
FILED | Friday, August 03, 2012 |
APPL NO | 13/566913 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0095 (20130101) A61K 47/48246 (20130101) A61K 47/48315 (20130101) A61K 47/48338 (20130101) A61K 49/00 (20130101) A61K 49/14 (20130101) A61K 49/0032 (20130101) A61K 49/0043 (20130101) A61K 49/0056 (20130101) A61K 49/085 (20130101) A61K 49/146 (20130101) A61K 51/088 (20130101) Peptides C07K 14/4728 (20130101) C07K 19/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695258 | Mrozek et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Randy A. Mrozek (Baltimore, Maryland); Joseph L. Lenhart (Port Deposit, Maryland); Michael C. Berg (Baltimore, Maryland) |
ABSTRACT | Methods of adjusting the mechanical properties of a polymeric material may include forming a polymer network having a plurality of permanent cross-links and coupled to a plurality of reversible cross-links, wherein the polymer network has a shear storage modulus of greater than about 4×104 Pa; and heating the polymer network using a heat source to dissociate the reversible cross-links, wherein heating the polymer network reduces the shear storage modulus to less than about 4×104 Pa. In some embodiments, a polymeric material may include a polymer network comprising a plurality of permanent cross-links and coupled to a plurality of reversible cross-links that are dissociable with the application of a stimulus and associable with the removal of the stimulus, wherein the shear storage modulus of the polymer network is less than about 4×104 Pa in the presence of the stimulus and greater than about 4×104 Pa in the absence of the stimulus. |
FILED | Monday, June 30, 2014 |
APPL NO | 14/318736 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/00 (20130101) C08F 22/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695368 | Tonkovich et al. |
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FUNDED BY |
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APPLICANT(S) | Velocys, Inc. (Plain City, Ohio) |
ASSIGNEE(S) | Velocys, Inc. (Plain City, Ohio) |
INVENTOR(S) | Anna Lee Tonkovich (Gilbert, Arizona); Ravi Arora (New Albany, Ohio); John Brophy (Bath, United Kingdom); Francis P. Daly (Delaware, Ohio); Soumitra Deshmukh (Dublin, Ohio); Maddalena Fanelli (Columbus, Ohio); Kai Tod Paul Jarosch (Bexley, Ohio); Timothy J. LaPlante (Powell, Ohio); Richard Q. Long (New Albany, Ohio); Terry Mazanec (Solon, Ohio); Daniel Francis Ryan (Brewster, Massachusetts); Laura J. Silva (Dublin, Ohio); Wayne W. Simmons (Dublin, Ohio); Bruce Stangeland (Berkeley, Ohio); Yong Wang (Richland, Washington); Thomas Yuschak (Lewis Center, Ohio); Steven T. Perry (Galloway, Ohio); Jeffrey Dale Marco (South Charleston, Ohio); Michael Alan Marchiando (London, Ohio); Robert Lewis Litt (Westerville, Ohio) |
ABSTRACT | This invention relates to a process for conducting a hydrocracking or a hydrotreating process in a microchannel reactor. This invention also relates to a process and apparatus for flowing a vapor and liquid into a plurality of microchannels in a microchannel processing unit. |
FILED | Thursday, February 11, 2016 |
APPL NO | 15/041119 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 21/12 (20130101) B01J 23/42 (20130101) B01J 23/75 (20130101) B01J 23/96 (20130101) B01J 35/023 (20130101) B01J 2219/00783 (20130101) B01J 2219/00788 (20130101) B01J 2219/00835 (20130101) B01J 2219/00873 (20130101) B01J 2219/00889 (20130101) B01J 2219/00891 (20130101) B01J 2219/00984 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/32 (20130101) C10G 45/02 (20130101) C10G 47/00 (20130101) C10G 47/02 (20130101) C10G 47/14 (20130101) Original (OR) Class C10G 2300/202 (20130101) C10G 2300/4018 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/582 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695415 | Daugherty et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Patrick Sean Daugherty (Santa Barbara, California); Jeffrey Rice (Goleta, California) |
ABSTRACT | Methods of making and using bacterial display polypeptide libraries using circularly permuted OmpX (CPX) variants are disclosed. The invention further relates to methods for enhancing the display of proteins and peptides at the surface of bacteria by optimizing linkers and incorporating mutations at positions 165 and 166 of CPX. |
FILED | Wednesday, May 20, 2015 |
APPL NO | 14/717679 |
ART UNIT | 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/195 (20130101) C07K 14/245 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/1037 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695525 | Kaukler |
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FUNDED BY |
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APPLICANT(S) | William Felix Kaukler (Huntsville, Alabama) |
ASSIGNEE(S) | The Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama) |
INVENTOR(S) | William Felix Kaukler (Huntsville, Alabama) |
ABSTRACT | The present invention relates to a method for the continuous production of low thermal conductivity endless filament yarns with a compact, homogeneous structural morphology. The presently disclosed methods utilize safe and recyclable ionic liquids (IL) to produce carbon fiber precursors from cellulose. The fibers are produced by the carbonization of cellulose carbon fiber precursors. The precursor fiber filaments have an increased tear resistance with simultaneously sufficient elongation, a round or crenulated cross-section, and homogeneous fiber morphology. The filament yarns exhibit performance characteristics similar to those produced from traditional viscous rayon. The resulting fibers are especially suited for aerospace applications in composite materials used at the limits of high temperatures, for instance in structures found in rocket nozzles or atmospheric reentry heat shields on spacecraft. |
FILED | Friday, September 26, 2014 |
APPL NO | 14/498754 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 37/006 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/103 (20130101) D01D 10/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696120 | Moser et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Alex E. Moser (Washington, District of Columbia); David L. Knies (Marbury, Maryland) |
ABSTRACT | An armor system includes a plate operably connected to a plunger, one or more solid bars of brittle material operably contained within a channel or tube, wherein the armor system is configured so that upon impact of a blast shock wave upon the plate, the plate transfers the blast shock wave to the plunger and then to the contents of the channel. Optionally, the channel also contains HFRM. |
FILED | Friday, November 18, 2016 |
APPL NO | 15/355124 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/02 (20130101) Original (OR) Class F41H 5/0492 (20130101) F41H 7/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696138 | Wan et al. |
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FUNDED BY |
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APPLICANT(S) | Xiaoke Wan (Herndon, Virginia); Jian Ge (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Xiaoke Wan (Herndon, Virginia); Jian Ge (Gainesville, Florida) |
ABSTRACT | A scanning monochromatic spatial low-coherent interferometer (S-LCI) can be used to simultaneously measure geometric thickness and refractive index. The probe beam of the scanning S-LCI can be an off-axis converging single wavelength laser beam, and the decomposed incident angles of the beam on the sample can be accurately defined in the Fourier domain. The angle dependent phase shift of a plane parallel plate or other sample can be obtained in a single system measurement. From the angle dependent phase shift, the geometric thickness and refractive index of the sample can be simultaneously obtained. Additionally or alternatively, the S-LCI system can interrogate the sample to profile the location and refractive index of one or more layers within the sample using the disclosed techniques. |
FILED | Tuesday, July 31, 2012 |
APPL NO | 14/236613 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0207 (20130101) G01B 9/0209 (20130101) G01B 9/02021 (20130101) G01B 9/02022 (20130101) G01B 9/02027 (20130101) G01B 11/06 (20130101) Original (OR) Class G01B 11/0675 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/45 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696161 | Belenkii et al. |
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FUNDED BY |
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APPLICANT(S) | Mikhail Belenkii (San Diego, California); Todd Barrett (San Diego, California); Timothy Brinkley (San Diego, California) |
ASSIGNEE(S) | Trex Enterprises Corporation (San Diego, California) |
INVENTOR(S) | Mikhail Belenkii (San Diego, California); Todd Barrett (San Diego, California); Timothy Brinkley (San Diego, California) |
ABSTRACT | A celestial compass kit. The kit includes an inclinometer, a camera system with a special telecentric fisheye lens for imaging at least one celestial object and a processor programmed with a celestial catalog providing known positions at specific times of at least one celestial object and algorithms for automatically calculating target direction information based on the inclination of the system as measured by the inclinometer and the known positions of at least one celestial object as provided by the celestial catalog and as imaged by the camera. The telecentric fisheye lens produces an image on the sensor located at or near the focal plane which remains spatially constant within sub-micron accuracies despite thermally produced changes in the focus of the lens. |
FILED | Tuesday, November 01, 2011 |
APPL NO | 13/373009 |
ART UNIT | 2443 — Computer Networks |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 17/34 (20130101) G01C 21/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696270 | Roy et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Ajit K Roy (Beavercreek, Ohio); Robert Wheeler, IV (Hilliard, Ohio); Sabyashachi Ganguli (Beavercreek, Ohio) |
ABSTRACT | An apparatus for thermal conductance measurement includes a first heater assembly having a beam, a platen disposed at an end of the beam, and a heating element and a Resistance Temperature Device (RDT) disposed on the platen. The embodiment further includes a second heater assembly having a second beam, a second platen disposed at an end of the second beam, and a second heating element and a second Resistance Temperature Device (RDT) disposed on the platen. A test rig is also included, and the first heater and second heater assembly are mated to the test rig and separated by a gap length. |
FILED | Monday, June 09, 2014 |
APPL NO | 14/299021 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/186 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/18 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696295 | Lin et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Jeffrey S. Lin (Silver Spring, Maryland); Andrew S. Pekosz (Towson, Maryland); Andrew B. Feldman (Columbia, Maryland) |
ABSTRACT | Certain embodiments of the present invention include a method for rapidly designing pharmaceutical preparations for preventing viral infection that have adapted to growth in various culturing systems but maintain antigenic similarity to the original virus. The method may include serial passaging a plurality of instances of a targeted virus strain from an infected first animal in respective droplets in second animal cells, in parallel synthesizing antibodies that neutralize the targeted virus strain in a third animal, and selecting the second animal cell-adapted viral lineages that are neutralized by the antibodies to identify second animal cell-adapted viral lineages having antigenic similarity to the targeted virus strain. |
FILED | Wednesday, January 18, 2017 |
APPL NO | 15/408842 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Peptides C07K 16/1018 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16021 (20130101) C12N 2760/16034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696313 | Santagata et al. |
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FUNDED BY |
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APPLICANT(S) | WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Sandro Santagata (Jamaica Plain, Massachusetts); Susan Lindquist (Chestnut Hill, Massachusetts); Luke J. Whitesell (Somerville, Massachusetts); Tan A. Ince (Miami, Florida) |
ABSTRACT | In some aspects, the invention relates to Heat Shock Protein-1 (HSF1) gene and HSF1 gene products. In some aspects, the invention provides methods of tumor diagnosis, prognosis, treatment-specific prediction, or treatment selection, the methods comprising assessing the level of HSF1 expression or HSF1 activation in a sample obtained from the tumor. In some aspects, the invention relates to the discovery that increased HSF1 expression and increased HSF1 activation correlate with poor outcome in cancer, e.g., breast cancer. |
FILED | Friday, October 05, 2012 |
APPL NO | 14/350328 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 33/57496 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696340 | Trusov et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Alexander A. Trusov (Irvine, California); Sergei A. Zotov (Irvine, California); Andrei M. Shkel (Irvine, California) |
ABSTRACT | A multi-axis microelectromechanical-systems (MEMS) inertial measurement unit (IMU) is fabricated in a vacuum sealed single packaged device. An FM vibratory gyroscope and an FM resonant accelerometer both for generating FM output signals is fabricated in the silicon chip using MEMS. A signal processor is coupled to the an FM vibratory gyroscope and to the FM resonant accelerometer for receiving the FM gyroscopic output signals and the FM accelerometer output signals. The signal processor generates simultaneous and decoupled measurement of input acceleration, input rotation rate, and temperature and/or temperature distribution within the IMU, self-calibration of the biases and scale factors of the IMU and its support electronics against temperature variations and other common mode errors, and reduction of the cross axis sensitivity by reducing acceleration errors in the gyroscope and rotation errors in the accelerometer. |
FILED | Friday, February 19, 2016 |
APPL NO | 15/048763 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5783 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) G01P 15/097 (20130101) G01P 15/125 (20130101) G01P 21/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696404 | Doyle et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Daniel D. Doyle (Wyoming, Michigan); Alan L. Jennings (Sahuarita, Arizona); Jonathan T. Black (Blacksburg, Virginia) |
ABSTRACT | A new apparatus and method for tracking a moving object with a moving camera provides a real-time, narrow field-of-view, high resolution and on target image by combining commanded motion with an optical flow algorithm for deriving motion and classifying background. Commanded motion means that movement of the pan, tilt and zoom (PTZ) unit is “commanded” by a computer, instead of being observed by the camera, so that the pan, tilt and zoom parameters are known, as opposed to having to be determined, significantly reducing the computational requirements for tracking a moving object. The present invention provides a single camera pan and tilt system where the known pan and tilt rotations are used to calculate predicted optical flow points in sequential images, so that resulting apparent movement can be subtracted from the movement determined by an optical flow algorithm to determine actual movement, following by use of a Kalman filter algorithm to predict subsequent locations of a determined moving object and command the pan and tilt unit to point the camera in that direction. |
FILED | Wednesday, May 06, 2015 |
APPL NO | 14/705922 |
ART UNIT | 2422 — Cable and Television |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/7864 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/2251 (20130101) H04N 5/23261 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696412 | Kanter et al. |
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FUNDED BY |
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APPLICANT(S) | Gregory S. Kanter (Chicago, Illinois); Daniel R. Reilly (Chicago, Illinois) |
ASSIGNEE(S) | Nucript LLC (Evanston, Illinois) |
INVENTOR(S) | Gregory S. Kanter (Chicago, Illinois); Daniel R. Reilly (Chicago, Illinois) |
ABSTRACT | A system and method for measuring the temporal delay an optical signal experiences along a path is provided it uses single photon sensitive detectors and multiple optical pulse rates. The multiple optical pulse rates are chosen to allow each to be isolated in post-processing even if only a single detector is employed. The detectors can be time-gated at a repetition rate synchronized but different from the optical pulse rates, including the use of a pulsed-pump up-conversion detector. The pulse rate choice allows improved performance, including an extension of the unambiguous temporal delay range. The ability to isolate the pulse rates can also be used for measuring multiple path delays simultaneously or for spectrally resolving path characteristics without requiring the use of spectral filtering. The post-processing function can be segmented to include an initial signal quality estimation step so further processing can be aborted if it is unlikely to succeed. |
FILED | Tuesday, January 20, 2015 |
APPL NO | 14/600112 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/487 (20130101) G01S 7/4865 (20130101) Original (OR) Class G01S 17/10 (20130101) G01S 17/107 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696430 | Park et al. |
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FUNDED BY |
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APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Michael Jihong Park (Somerville, Massachusetts); Charles Coldwell (Belmont, Massachusetts) |
ABSTRACT | Described herein is an unmanned aerial vehicle (UAV) system that incorporates sensor data to statistically minimize the time to autonomously locate a target on the ground. The system uses a two-stage approach to finding the RF target: 1) randomized flight, such as Lévy fight, to search the ground space and, 2) a geo-localization process, such as a simplex minimization process, to home in on the target. |
FILED | Tuesday, August 26, 2014 |
APPL NO | 14/468905 |
ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 23/005 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/39 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0094 (20130101) G05D 1/0202 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696486 | Zheng et al. |
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FUNDED BY |
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APPLICANT(S) | Oracle International Corporation (Redwood City, California) |
ASSIGNEE(S) | ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California) |
INVENTOR(S) | Xuezhe Zheng (San Diego, California); Ivan Shubin (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
ABSTRACT | A photonic integrated circuit (PIC) is described. This PIC includes an inverse facet mirror on a silicon optical waveguide for optical proximity coupling between two silicon-on-insulator (SOI) chips placed face to face. Accurate mirror facets may be fabricated in etch pits using a silicon micro-machining technique, with wet etching of the silicon <110> facet at an angle of 45° when etched through the <100> surface. Moreover, by filling the etch pit with polycrystalline silicon or another filling material that has an index of refraction similar to silicon (such as a silicon-germanium alloy), a reflecting mirror with an accurate angle can be formed at the end of the silicon optical waveguide using: a metal coating, a dielectric coating, thermal oxidation, or selective silicon dry etching removal of one side of the etch pit to define a cavity. |
FILED | Wednesday, July 31, 2013 |
APPL NO | 13/955705 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) Original (OR) Class G02B 6/136 (20130101) G02B 6/4214 (20130101) G02B 2006/12061 (20130101) G02B 2006/12104 (20130101) G02B 2006/12176 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696531 | Hersee |
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FUNDED BY |
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APPLICANT(S) | Stephen D. Hersee (Cudjoe Key, Florida) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Stephen D. Hersee (Cudjoe Key, Florida) |
ABSTRACT | Exemplary embodiments provide solid-state microscope (SSM) devices and methods for processing and using the SSM devices. The solid-state microscope devices can include a light emitter array having a plurality of light emitters with each light emitter individually addressable. During operation, each light emitter can be biased in one of three operating states including an emit state, a detect state, and an off state. The light emitter can include an LED (light emitting diode) including, but not limited to, a nanowire based LED or a planar LED to provide various desired image resolutions for the SSM devices. In an exemplary embodiment, for near-field microscopy, the resolution of the SSM microscope can be essentially defined by the pitch p, i.e., center-to-center spacing between two adjacent light emitters, of the light emitter array. |
FILED | Wednesday, January 07, 2015 |
APPL NO | 14/591773 |
ART UNIT | 2493 — Cryptography and Security |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 21/00 (20130101) G02B 21/002 (20130101) G02B 21/0004 (20130101) Original (OR) Class G02B 21/06 (20130101) G02B 21/36 (20130101) G02B 21/361 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/156 (20130101) H01L 33/06 (20130101) H01L 33/18 (20130101) H01L 33/24 (20130101) H01L 33/0025 (20130101) H01L 33/32 (20130101) H01L 33/36 (20130101) H01L 33/0075 (20130101) H01L 2933/0016 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697461 | Modha |
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FUNDED BY |
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APPLICANT(S) | Dharmendra S. Modha (San Jose, California) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Dharmendra S. Modha (San Jose, California) |
ABSTRACT | In one embodiment, the present invention provides a method for interconnecting neurons in a neural network. At least one node among a first set of nodes is interconnected to at least one node among a second set of nodes, and nodes of the first and second set are arranged in a lattice. At least one node of the first set represents a sensory-motor modality of the neural network. At least one node of the second set is a union of at least two nodes of the first set. Each node in the lattice has an acyclic digraph comprising multiple vertices and directed edges. Each vertex represents a neuron population. Each directed edge comprises multiple synaptic connections. Vertices in different acyclic digraphs are interconnected using an acyclic bottom-up digraph. The bottom-up digraph has a corresponding acyclic top-down digraph. Vertices in the bottom-up digraph are interconnected to vertices in the top-down digraph. |
FILED | Friday, August 24, 2012 |
APPL NO | 13/594045 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class G06N 3/10 (20130101) G06N 3/049 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697462 | Cruz-Albrecht et al. |
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FUNDED BY |
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APPLICANT(S) | Jose M. Cruz-Albrecht (Oak Park, California); Narayan Srinivasa (Oak Park, California); Peter Petre (Oak Park, California); Youngkwan Cho (Los Angeles, California); Aleksey Nogin (Fresno, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Jose M. Cruz-Albrecht (Oak Park, California); Narayan Srinivasa (Oak Park, California); Peter Petre (Oak Park, California); Youngkwan Cho (Los Angeles, California); Aleksey Nogin (Fresno, California) |
ABSTRACT | A synaptic time-multiplexed (STM) neuromorphic network includes a neural fabric that includes nodes and switches to define inter-nodal connections between selected nodes of the neural fabric. The STM neuromorphic network further includes a neuromorphic controller to form subsets of a set of the inter-nodal connections representing a fully connected neural network. Each subset is formed during a different time slot of a plurality of time slots of a time multiplexing cycle of the STM neuromorphic network. In combination, the inter-nodal connection subsets implement the fully connected neural network. A method of synaptic time multiplexing a neuromorphic network includes providing the neural fabric and forming the subsets of the set of inter-nodal connections. |
FILED | Saturday, January 03, 2015 |
APPL NO | 14/588929 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697467 | Riabov et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (White Plains, New York); Octavian Udrea (Ossining, New York) |
ABSTRACT | In at least one embodiment, a method and a system for determining a set of plans that best match a set of preferences. The method may include receiving into a goal specification interface at least one goal to be accomplished by the set of plans; receiving into a preference engine a pattern that includes preferences; generating a planning problem by using the preference engine; generating a set of plans by at least one planner; and providing the set of plans for selection of one plan to deploy. In a further embodiment, the preferences may be an occurrence or non-occurrence of at least one component, an occurrence of one component over another component, an ordering between at least two components, an existence or non-existence of at least one tag in a final stream, an existence of one tag over another tag in the final stream. |
FILED | Wednesday, May 21, 2014 |
APPL NO | 14/283945 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697468 | Reifman et al. |
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FUNDED BY |
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APPLICANT(S) | United States Government, as represented by the Secretary of the Army (Ft. Detrick, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jaques Reifman (New Market, Maryland); Maxim Y. Khitrov (Rockville, Maryland); Andrew T. Reisner (Newtonville, Massachusetts); Liangyou Chen (Hanover Park, Illinois); Thomas McKenna (Frederick, Maryland) |
ABSTRACT | A system is disclosed having a storage, a communications module for interacting with a medical measurement device, an analysis controller, and a test module that allows for the testing and evaluating of decision-support algorithms. A method for testing decision-support algorithms is disclosed having the steps of receiving into storage of a ruggedized, compact computer at least one decision-support algorithm; detecting with a communications module the initiation of a vital-sign monitoring session; receiving and storing vital-sign information into storage by the communications module; pushing the stored vital-sign information by an analysis controller to a test module running the stored at least one decision-support algorithm; and providing at least one output from the decision-support algorithm to at least one of a database and a display. |
FILED | Thursday, March 05, 2015 |
APPL NO | 14/639745 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0255 (20130101) A61B 5/02416 (20130101) A61B 5/02438 (20130101) A61B 5/7221 (20130101) A61B 5/14542 (20130101) A61B 2560/029 (20130101) Electric Digital Data Processing G06F 19/345 (20130101) G06F 19/3412 (20130101) G06F 19/3418 (20130101) Computer Systems Based on Specific Computational Models G06N 5/045 (20130101) Original (OR) Class Transmission Systems for Measured Values, Control or Similar Signals G08C 19/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697830 | Kingsbury et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Brian E. D. Kingsbury (Cortlandt Manor, New York); Lidia Mangu (Yorktown Heights, New York); Michael A. Picheny (White Plains, New York); George A. Saon (Stamford, Connecticut) |
ABSTRACT | A method for spoken term detection, comprising generating a time-marked word list, wherein the time-marked word list is an output of an automatic speech recognition system, generating an index from the time-marked word list, wherein generating the index comprises creating a word loop weighted finite state transducer for each utterance, i, receiving a plurality of keyword queries, and searching the index for a plurality of keyword hits. |
FILED | Thursday, June 25, 2015 |
APPL NO | 14/750604 |
ART UNIT | 2676 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/193 (20130101) Original (OR) Class G10L 2015/085 (20130101) G10L 2015/088 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697877 | Shanbhag et al. |
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FUNDED BY |
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APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
INVENTOR(S) | Naresh Shanbhag (Champaign, Illinois); Mingu Kang (Savoy, Illinois); Min-Sun Keel (Champaign, Illinois) |
ABSTRACT | A compute memory system can include a memory array and a controller that generates N-ary weighted (e.g., binary weighted) access pulses for a set of word lines during a single read operation. This multi-row read generates a charge on a bit line representing a word stored in a column of the memory array. The compute memory system further includes an embedded analog signal processor stage through which voltages from bit lines can be processed in the analog domain. Data is written into the memory array in a manner that stores words in columns instead of the traditional row configuration. |
FILED | Thursday, February 05, 2015 |
APPL NO | 14/614743 |
ART UNIT | 2824 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 7/12 (20130101) Original (OR) Class G11C 7/16 (20130101) G11C 7/1006 (20130101) G11C 8/04 (20130101) G11C 8/08 (20130101) G11C 11/418 (20130101) G11C 11/419 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697924 | Nanni et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Emilio Alessandro Nanni (Cambridge, Massachusetts); William Sproull Graves (Marblehead, Massachusetts); Franz Xaver Kaertner (Newton, Massachusetts); David Eugene Moncton (Newton, Massachusetts) |
ABSTRACT | Coherent electronic current is generated by generating and transmitting an electron bunch along a longitudinal axis. The electron bunch is then directed onto a target, wherein the target imparts a transverse spatial modulation to the electron bunch via diffraction contrast or phase contrast. The transverse spatial modulation of the electron bunch is then transferred to the longitudinal axis via an emittance exchange beamline, creating a periodically modulated distribution of coherent electronic current. |
FILED | Tuesday, March 31, 2015 |
APPL NO | 14/674482 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/06 (20130101) G21K 5/00 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 23/18 (20130101) X-ray Technique H05G 2/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698254 | Friedman et al. |
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FUNDED BY |
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APPLICANT(S) | Adam L. Friedman (Silver Spring, Maryland); Olaf M. T. van 't Erve (Falls Church, Virginia); Connie H. Li (Alexandria, Virginia); Jeremy T. Robinson (Washington, District of Columbia); Berend T. Jonker (Waldorf, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Adam L. Friedman (Silver Spring, Maryland); Olaf M. T. van 't Erve (Falls Church, Virginia); Connie H. Li (Alexandria, Virginia); Jeremy T. Robinson (Washington, District of Columbia); Berend T. Jonker (Waldorf, Maryland) |
ABSTRACT | This disclosure describes a method of making a tunnel barrier-based electronic device, in which the tunnel barrier and transport channel are made of the same material—graphene. A homoepitaxial tunnel barrier/transport device is created using a monolayer chemically modified graphene sheet as a tunnel barrier on another monolayer graphene sheet. This device displays enhanced spintronic properties over heteroepitaxial devices and is the first to use graphene as both the tunnel barrier and channel. |
FILED | Monday, March 20, 2017 |
APPL NO | 15/463229 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/042 (20130101) H01L 21/043 (20130101) H01L 21/02115 (20130101) H01L 21/02293 (20130101) H01L 21/02527 (20130101) H01L 29/45 (20130101) H01L 29/167 (20130101) H01L 29/1606 (20130101) H01L 29/66984 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698564 | Shubin et al. |
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FUNDED BY |
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APPLICANT(S) | Oracle International Corporation (Redwood Shores, California) |
ASSIGNEE(S) | ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California) |
INVENTOR(S) | Ivan Shubin (San Diego, California); Xuezhe Zheng (San Diego, California); Jin-Hyoung Lee (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
ABSTRACT | A multi-chip module (MCM) includes: an interposer, a photonic chip, an optical gain chip, and a waveguide-fiber connector. The photonic chip, which may be electrically coupled to the interposer, may be implemented using a silicon-on-insulator (SOI) technology, and may include an optical waveguide that conveys an optical signal. Moreover, the optical gain chip, which may be electrically coupled to the interposer, may include a III-V compound semiconductor, and may include a second optical waveguide that conveys the optical signal and that is vertically aligned with the optical waveguide relative to a top surface of the interposer. Furthermore, the waveguide-fiber connector may be mechanically coupled to the interposer, and remateably mechanically coupled to an optical fiber coupler that includes the optical fiber. The waveguide-fiber connector may convey the optical signal between the optical waveguide in the photonic chip and the optical fiber. |
FILED | Tuesday, February 09, 2016 |
APPL NO | 15/019631 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/30 (20130101) G02B 6/4292 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/026 (20130101) Original (OR) Class H01S 5/0206 (20130101) H01S 5/1014 (20130101) H01S 5/3013 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698735 | McCue et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Jamin McCue (Columbus, Ohio); Vipul J. Patel (Dayton, Ohio); Waleed Khalil (Dublin, Ohio); Brian Dupaix (Columbus, Ohio); James Wilson (Washington, District of Columbia); Steven R Dooley (Beavercreek, Ohio) |
ABSTRACT | A Low Voltage Differential Signaling (LVDS) compliant receiver includes a differential amplifier having inputs and outputs. A first input coupling capacitor and second input coupling capacitor are electrically coupled to each of the first differential input and the second differential input, respectively. The receiver also includes a first and a second regenerative feedback latching mechanism, and the first regenerative feedback latching mechanism is electrically coupled between the first input coupling capacitor and the first differential output. The second regenerative feedback latching mechanism is electrically coupled between the second input coupling capacitor and the second differential output. An integrated circuit substrate includes each of the differential amplifier, the first differential input, the second differential input, the first differential output, the second differential output, the first regenerative feedback latching apparatus, and the second regenerative feedback latching apparatus are contained thereon. The first and the second input coupling capacitor are on-chip. |
FILED | Monday, December 14, 2015 |
APPL NO | 14/967766 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Amplifiers H03F 1/301 (20130101) Original (OR) Class H03F 3/45179 (20130101) H03F 2203/45112 (20130101) H03F 2203/45116 (20130101) H03F 2203/45156 (20130101) Transmission H04B 1/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698812 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | Jintao Zhang (Princeton, New Jersey); Zhuo Wang (Princeton, New Jersey); Naveen Verma (Princeton, New Jersey) |
ABSTRACT | A multiplying analog to digital converter including an analog to digital converter (ADC) having a sample input and a feedback input and an ADC output configured with a feedback path configured to couple the ADC output to a digital to analog converter. A feedback attenuator is disposed in the feedback path, the feedback attenuator being configured to attenuate a feedback signal coupled to the feedback input, the feedback attenuator being configured to provide analog multiplication observed at the ADC output. A barrel shifter is configured to provide digital multiplication of the ADC output. The feedback attenuator may be configured as a divider network. The feedback attenuator may be configured to provide attenuation using only passive components. The feedback attenuator may be configured as a capacitive divider network. The feedback attenuator may be configured to provide attenuation ranging between 1 and 0.5. |
FILED | Tuesday, September 27, 2016 |
APPL NO | 15/277434 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/442 (20130101) H03M 1/466 (20130101) H03M 1/1071 (20130101) H03M 1/1245 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698844 | Ames |
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FUNDED BY |
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APPLICANT(S) | Blue Line Engineering Company (Colorado Springs, Colorado) |
ASSIGNEE(S) | Blue Line Engineering Company (Colorado Springs, Colorado) |
INVENTOR(S) | Gregory Ames (Colorado Springs, Colorado) |
ABSTRACT | The present invention detects, determines, and mitigates signal-path processing errors. An extracted and inverted reference signal is compared to the carrier signal produced by various functional components to determine the error introduced to that signal by functional components. After the signal has been processed by various signal-processing components, the signal can once again be compared to the inverted reference signal so that a signal-path processing bias can be determined. Using that determination, a signal modification can be initiated to substantially reduce or eliminate all signal-path processing error. |
FILED | Friday, January 29, 2016 |
APPL NO | 15/010719 |
ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Transmission H04B 1/16 (20130101) Original (OR) Class H04B 1/30 (20130101) H04B 17/21 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698913 | Foster et al. |
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FUNDED BY |
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APPLICANT(S) | The John Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHN HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Mark Foster (Baltimore, Maryland); Amit Bhatia (Baltimore, Maryland) |
ABSTRACT | A phase-modulated optical link and methods are provided to suppress distortions in phase-encoded analog photonic links. The phase-modulated optical link includes a distortion compensation element. The distortion compensation element includes an optical comb generator that is seeded by a phase-encoded optical signal. The methods include generating an optical comb seeded by a portion of a phase-encoded optical signal and isolating desired peaks to be combined with a separate portion of the phase-encoded optical signal. |
FILED | Monday, June 08, 2015 |
APPL NO | 14/733360 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Transmission H04B 10/503 (20130101) H04B 10/548 (20130101) H04B 10/2507 (20130101) H04B 10/2575 (20130101) H04B 10/5561 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698915 | Dailey et al. |
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FUNDED BY |
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APPLICANT(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
ASSIGNEE(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
INVENTOR(S) | James Dailey (Basking, New Jersey); Anjali Agarwal (Basking Ridge, New Jersey); Paul Toliver (Basking Ridge, New Jersey); Colin McKinstrie (Basking Ridge, New Jersey); Nicholas Peters (Knoxville, Tennessee) |
ABSTRACT | A system and method for processing an input signal includes a non-linear material component for receiving the signal. The non-linear material component is selected to mix the input signal with an optical pump wave to output an optical signal. The system also includes a parametric amplifier coupled to the non-linear material to obtain the optical signal and to amplify the optical signal to generate an amplified signal and an amplified idler which is a conjugate image of the amplified signal. The system also includes a frequency converter, to obtain the amplified signal and the amplified idler from the parametric amplifier and to convert the amplified signal and the amplified idler into a first output and a second output. The system also includes a first spectral sampling and processing apparatus to obtain and process the first output. |
FILED | Friday, May 27, 2016 |
APPL NO | 15/166916 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Transmission H04B 10/90 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09699096 | Satpathy et al. |
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FUNDED BY |
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APPLICANT(S) | Sudhir Satpathy (Hillsboro, Oregon); Himanshu Kaul (Portland, Oregon); Mark Anders (Hillsboro, Oregon); Sanu Mathew (Hillsboro, Oregon); Gregory Chen (Hillsboro, Oregon); Ram Krishnamurthy (Portland, Oregon) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Sudhir Satpathy (Hillsboro, Oregon); Himanshu Kaul (Portland, Oregon); Mark Anders (Hillsboro, Oregon); Sanu Mathew (Hillsboro, Oregon); Gregory Chen (Hillsboro, Oregon); Ram Krishnamurthy (Portland, Oregon) |
ABSTRACT | Disclosed herein is a router configured for priority-based routing. The router is configured to receive a plurality of packets, wherein each packet is assigned a priority value. The router includes an output circuit configured to select the packet with the highest priority value. The output circuit is configured to forward the priority value of the selected packet to a second router. The output circuit is configured to transfer the selected packet to the second router when the link between the first router and the second router is available. |
FILED | Thursday, December 26, 2013 |
APPL NO | 14/141356 |
ART UNIT | 2476 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/30 (20130101) H04L 47/56 (20130101) H04L 47/2458 (20130101) Original (OR) Class H04L 47/6275 (20130101) H04L 49/109 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09699665 | Learned |
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FUNDED BY |
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APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Rachel E. Learned (Waltham, Massachusetts) |
ABSTRACT | In a radio network having a plurality of first users on channel (FUOCs) and one or more second users on channel (SUOCs), a method and apparatus for a SUOC to select a channel to co-occupy based in part upon the expected impact on the FUOC. The FUOC collects signal parameters associated with the FUOC, such as actual rate, bandwidth, received signal power, and noise power, and uses the signal parameters to calculate the expected impact. In some embodiments, the expected impact is proportional to the ratio of the FUOC's actual rate and the FUOC's possible code rate. |
FILED | Tuesday, December 30, 2014 |
APPL NO | 14/585780 |
ART UNIT | 2476 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/00 (20130101) Wireless Communication Networks H04W 24/00 (20130101) Original (OR) Class H04W 24/02 (20130101) H04W 28/18 (20130101) H04W 84/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 09694190 | Tolosa et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Vanessa Tolosa (Oakland, California); Satinderpall S. Pannu (Pleasanton, California); Heeral Sheth (Oakland, California); Angela C. Tooker (Dublin, California); Kedar G. Shah (San Francisco, California); Sarah H. Felix (Oakland, California) |
ABSTRACT | An implantable device has a cylindrical base, at least one electrode on the cylindrical base, at least one electrically conducting lead on the cylindrical base connected to the electrode wherein the electrically conducting lead has a feature size of <10 micrometers. A protective coating on the cylindrical base covers the at least one electrically conducting lead. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/213733 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/3756 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/02 (20130101) H05K 3/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694352 | Narula et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Chaitanya K. Narula (Knoxville, Tennessee); Xiaofan Yang (Knoxville, Tennessee) |
ABSTRACT | A catalyst composition includes a heterobimetallic zeolite characterized by a chabazite structure loaded with copper ions and at least one trivalent metal ion other than Al3+. The catalyst composition decreases NOx emissions in diesel exhaust and is suitable for operation in a catalytic converter. |
FILED | Wednesday, September 28, 2016 |
APPL NO | 15/278785 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/8628 (20130101) B01D 53/8631 (20130101) B01D 53/9418 (20130101) B01D 2255/50 (20130101) B01D 2255/20738 (20130101) B01D 2255/20761 (20130101) B01D 2258/012 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/061 (20130101) B01J 29/064 (20130101) B01J 29/068 (20130101) B01J 29/072 (20130101) B01J 29/76 (20130101) Original (OR) Class B01J 29/763 (20130101) B01J 29/783 (20130101) B01J 29/7049 (20130101) B01J 29/7065 (20130101) B01J 2229/183 (20130101) B01J 2229/186 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/02 (20130101) C01B 39/06 (20130101) C01B 39/026 (20130101) C01B 39/46 (20130101) C01B 39/065 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694422 | Christoforo et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Mark Greyson Christoforo (Los Altos Hills, California); Saahil Mehra (Saratoga, California); Alberto Salleo (San Francisco, California); Peter Peumans (Herfelingen, Belgium) |
ABSTRACT | In one embodiment, a method is provided for fabrication of a semitransparent conductive mesh. A first solution having conductive nanowires suspended therein and a second solution having nanoparticles suspended therein are sprayed toward a substrate, the spraying forming a mist. The mist is processed, while on the substrate, to provide a semitransparent conductive material in the form of a mesh having the conductive nanowires and nanoparticles. The nanoparticles are configured and arranged to direct light passing through the mesh. Connections between the nanowires provide conductivity through the mesh. |
FILED | Friday, January 09, 2015 |
APPL NO | 14/593840 |
ART UNIT | 2898 — Semiconductors/Memory |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0025 (20130101) B22F 1/0025 (20130101) B22F 1/0044 (20130101) B22F 1/0059 (20130101) Original (OR) Class B22F 3/002 (20130101) B22F 3/002 (20130101) B22F 3/24 (20130101) B22F 3/105 (20130101) B22F 7/004 (20130101) B22F 7/004 (20130101) B22F 2003/248 (20130101) B22F 2301/255 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 9/02 (20130101) Alloys C22C 32/0021 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/123 (20160101) C23C 24/00 (20130101) C23C 24/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1884 (20130101) H01L 31/022466 (20130101) H01L 51/442 (20130101) H01L 51/447 (20130101) H01L 51/5268 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695051 | Strobel et al. |
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FUNDED BY |
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APPLICANT(S) | CARNEGIE INSTITUTION OF WASHINGTON (Washington, District of Columbia) |
ASSIGNEE(S) | CARNEGIE INSTITUTION OF WASHINGTON (Washington, District of Columbia) |
INVENTOR(S) | Timothy A. Strobel (Washington, District of Columbia); Duck Young Kim (Washington, District of Columbia); Oleksandr O. Kurakevych (Washington, District of Columbia) |
ABSTRACT | The invention relates to a new phase of silicon, Si24, and a method of making the same. Si24 has a quasi-direct band gap, with a direct gap value of 1.34 eV and an indirect gap value of 1.3 eV. The invention also relates to a compound of the formula Na4Si24 and a method of making the same. Na4Si24 may be used as a precursor to make Si24. |
FILED | Tuesday, July 08, 2014 |
APPL NO | 14/903131 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/00 (20130101) C01B 33/02 (20130101) Original (OR) Class C01B 33/06 (20130101) C01B 33/021 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695068 | Cho et al. |
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FUNDED BY |
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APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Young I. Cho (Cherry Hill, New Jersey); Alexander Fridman (Philadelphia, Pennsylvania); Alexander Rabinovich (Cherry Hill, New Jersey); Daniel J. Cho (Wayne, Pennsylvania) |
ABSTRACT | The present invention consists of a method of pre-treatment of adulterated water for distillation, including adulterated water produced during hydraulic fracturing (“fracking”) of shale rock during natural gas drilling. In particular, the invention is directed to a method of treating adulterated water, said adulterated water having an initial level of bicarbonate ion in a range of about 250 ppm to about 5000 ppm and an initial level of calcium ion in a range of about 500 ppm to about 50,000 ppm, said method comprising contacting the adulterated water with a non-thermal arc discharge plasma to produce plasma treated water having a level of bicarbonate ion of less than about 100 ppm. Optionally, the plasma treated water may be further distilled. |
FILED | Tuesday, November 05, 2013 |
APPL NO | 14/071990 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/001 (20130101) C02F 1/04 (20130101) C02F 1/4602 (20130101) C02F 1/4608 (20130101) Original (OR) Class C02F 2201/46175 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695094 | Beck et al. |
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FUNDED BY |
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APPLICANT(S) | Virent, Inc. (Madison, Wisconsin) |
ASSIGNEE(S) | Virent, Inc. (Madison, Wisconsin) |
INVENTOR(S) | Taylor Beck (Madison, Wisconsin); Brian Blank (Monona, Wisconsin); Casey Jones (Madison, Wisconsin); Elizabeth Woods (Middleton, Wisconsin); Randy Cortright (Madison, Wisconsin) |
ABSTRACT | Methods, catalysts, and reactor systems for producing in high yield aromatic chemicals and liquid fuels from a mixture of oxygenates comprising di- and polyoxygenates are disclosed. Also disclosed are methods, catalysts, and reactor systems for producing aromatic chemicals and liquid fuels from oxygenated hydrocarbons such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like; and methods, catalysts, and reactor systems for producing the mixture of oxygenates from oxygenated hydrocarbons such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like. The disclosed catalysts for preparing the mixture of oxygenates comprise a NinSnm alloy and a crystalline alumina support. |
FILED | Friday, July 22, 2016 |
APPL NO | 15/217715 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/066 (20130101) B01J 23/14 (20130101) B01J 23/755 (20130101) B01J 23/835 (20130101) B01J 23/888 (20130101) B01J 23/6527 (20130101) B01J 29/46 (20130101) B01J 29/90 (20130101) B01J 37/0201 (20130101) B01J 37/0213 (20130101) B01J 38/02 (20130101) B01J 38/12 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 35/06 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) C07C 1/2072 (20130101) C07C 29/60 (20130101) C07C 45/002 (20130101) C07C 51/377 (20130101) Heterocyclic Compounds C07D 301/02 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/46 (20130101) C10G 3/47 (20130101) C10G 3/48 (20130101) C10G 3/49 (20130101) C10G 3/50 (20130101) C10G 2300/1014 (20130101) C10G 2400/30 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/584 (20151101) Y02P 20/588 (20151101) Y02P 30/20 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695407 | Cascao-Pereira et al. |
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FUNDED BY |
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APPLICANT(S) | Danisco US Inc. (Palo Alto, California) |
ASSIGNEE(S) | DANISCO US INC (, California) |
INVENTOR(S) | Luis Cascao-Pereira (Redwood City, California); Thijs Kaper (Half Moon Bay, California); Bradley R. Kelemen (Menlo Park, California); Amy D. Liu (Sunnyvale, California) |
ABSTRACT | The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions. |
FILED | Thursday, March 19, 2015 |
APPL NO | 14/662932 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 302/01091 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695426 | Liao et al. |
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FUNDED BY |
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APPLICANT(S) | James C. Liao (Los Angeles, California); Shota Atsumi (Davis, California); Anthony F. Cann (Los Angeles, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | James C. Liao (Los Angeles, California); Shota Atsumi (Davis, California); Anthony F. Cann (Los Angeles, California) |
ABSTRACT | Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate. |
FILED | Wednesday, August 12, 2009 |
APPL NO | 12/540334 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) C12P 7/16 (20130101) C12P 7/22 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695433 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Novozymes Inc. (Davis, California) |
ASSIGNEE(S) | Novozymes Inc. (Davis, California) |
INVENTOR(S) | Yu Zhang (Beijing, China PRC); Ye Liu (Beijing, China PRC); Junxin Duan (Beijing, China PRC); Lan Tang (Beijing, China PRC); Brett McBrayer (Sacramento, California) |
ABSTRACT | The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
FILED | Thursday, November 22, 2012 |
APPL NO | 14/356482 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/248 (20130101) C12N 9/2445 (20130101) C12N 15/1137 (20130101) C12N 15/8242 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/141 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) C12P 19/14 (20130101) Enzymes C12Y 302/01008 (20130101) C12Y 302/01021 (20130101) C12Y 302/01037 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/17 (20130101) Y02E 50/343 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695586 | Reading |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Matthew W. Reading (Albuquerque, New Mexico) |
ABSTRACT | Technologies for making self-erecting structures are described herein. An exemplary self-erecting structure comprises a plurality of shape-memory members that connect two or more hub components. When forces are applied to the self-erecting structure, the shape-memory members can deform, and when the forces are removed the shape-memory members can return to their original pre-deformation shape, allowing the self-erecting structure to return to its own original shape under its own power. A shape of the self-erecting structure depends on a spatial orientation of the hub components, and a relative orientation of the shape-memory members, which in turn depends on an orientation of joining of the shape-memory members with the hub components. |
FILED | Monday, May 16, 2016 |
APPL NO | 15/156132 |
ART UNIT | 3633 — Static Structures, Supports and Furniture |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/443 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/34357 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0481 (20130101) Antennas, i.e Radio Aerials H01Q 15/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696077 | Gomes et al. |
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FUNDED BY |
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APPLICANT(S) | Alberto Regio Gomes (St. Joseph, Michigan); Steven J. Kuehl (Stevensville, Michigan); Andrew D. Litch (St. Joseph, Michigan); Guolian Wu (St. Joseph, Michigan) |
ASSIGNEE(S) | Whirlpool Corporation (Benton Harbor, Michigan) |
INVENTOR(S) | Alberto Regio Gomes (St. Joseph, Michigan); Steven J. Kuehl (Stevensville, Michigan); Andrew D. Litch (St. Joseph, Michigan); Guolian Wu (St. Joseph, Michigan) |
ABSTRACT | A refrigerator appliance including a multi-capacity compressor and a refrigerant circuit with two conduits and pressure reducing devices arranged in parallel between an evaporator and a condenser. Refrigerant can flow through one, both or none of the conduits and pressure reducing devices. The appliance also has a heat exchanger in contact with either one pressure reducing device, or one conduit between the pressure reducing device and the valve system. The appliance also includes a controller for priming the compressor above a nominal capacity for a predetermined or calculated duration at the beginning of an ON-cycle. |
FILED | Tuesday, February 21, 2012 |
APPL NO | 13/400804 |
ART UNIT | 3744 — Static Structures, Supports and Furniture |
CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 5/02 (20130101) F25B 40/00 (20130101) F25B 49/022 (20130101) Original (OR) Class F25B 2341/0661 (20130101) F25B 2400/052 (20130101) F25B 2600/0251 (20130101) F25B 2600/0253 (20130101) F25B 2600/2511 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 29/00 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/741 (20130101) Y02B 40/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696216 | DeSilva et al. |
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FUNDED BY |
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APPLICANT(S) | Siemens Energy, Inc. (Orlando, Florida) |
ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
INVENTOR(S) | Upul P. DeSilva (Oviedo, Florida); Heiko Claussen (North Brunswick, New Jersey) |
ABSTRACT | An apparatus for controlling operation of a gas turbine engine including at least one acoustic transmitter/receiver device located on a flow path boundary structure. The acoustic transmitter/receiver device includes an elongated sound passage defined by a surface of revolution having opposing first and second ends and a central axis extending between the first and second ends, an acoustic sound source located at the first end, and an acoustic receiver located within the sound passage between the first and second ends. The boundary structure includes an opening extending from outside the boundary structure to the flow path, and the second end of the surface of revolution is affixed to the boundary structure at the opening for passage of acoustic signals between the sound passage and the flow path. |
FILED | Thursday, March 05, 2015 |
APPL NO | 14/639563 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/00 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/303 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/003 (20130101) G01H 3/00 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/24 (20130101) Original (OR) Class G01K 13/02 (20130101) G01K 2013/024 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696222 | Sumant et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Anirudha V. Sumant (Plainfield, Illinois); Xinpeng Wang (Franklin Park, New Jersey) |
ABSTRACT | A UNCD nanowire comprises a first end electrically coupled to a first contact pad which is disposed on a substrate. A second end is electrically coupled to a second contact pad also disposed on the substrate. The UNCD nanowire is doped with a dopant and disposed over the substrate. The UNCD nanowire is movable between a first configuration in which no force is exerted on the UNCD nanowire and a second configuration in which the UNCD nanowire bends about the first end and the second end in response to a force. The UNCD nanowire has a first resistance in the first configuration and a second resistance in the second configuration which is different from the first resistance. The UNCD nanowire is structured to have a gauge factor of at least about 70, for example, in the range of about 70 to about 1,800. |
FILED | Monday, August 08, 2016 |
APPL NO | 15/231421 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/14 (20130101) G01B 7/18 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/042 (20130101) H01L 21/043 (20130101) H01L 21/308 (20130101) H01L 29/04 (20130101) H01L 29/167 (20130101) H01L 29/0669 (20130101) H01L 29/0673 (20130101) H01L 29/1602 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696256 | Ohodnicki, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | Paul R. Ohodnicki, Jr. (Alison Park, Pennsylvania); John P. Baltrus (Jefferson Hills, Pennsylvania); Thomas D. Brown (Finleyville, Pennsylvania) |
ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Paul R. Ohodnicki, Jr. (Alison Park, Pennsylvania); John P. Baltrus (Jefferson Hills, Pennsylvania); Thomas D. Brown (Finleyville, Pennsylvania) |
ABSTRACT | The disclosure relates to a plasmon resonance-based method for H2 sensing in a gas stream utilizing a hydrogen sensing material. The hydrogen sensing material is comprises Pd-based or Pt-based nanoparticles having an average nanoparticle diameter of less than about 100 nanometers dispersed in an inert matrix having a bandgap greater than or equal to 5 eV, and an oxygen ion conductivity less than approximately 10−7 S/cm at a temperature of 700° C. Exemplary inert matrix materials include SiO2, Al2O3, and Si3N4 as well as modifications to modify the effective refractive indices through combinations and/or doping of such materials. The hydrogen sensing material utilized in the method of this disclosure may be prepared using means known in the art for the production of nanoparticles dispersed within a supporting matrix including sol-gel based wet chemistry techniques, impregnation techniques, implantation techniques, sputtering techniques, and others. |
FILED | Tuesday, October 20, 2015 |
APPL NO | 14/887660 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/554 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696317 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Haw Yang (Princeton Junction, New Jersey); Chih-Hao Hsia (Plainsboro, New Jersey) |
ABSTRACT | Novel Mn2+-doped quantum dots are provided. These Mn2+-doped quantum dots exhibit excellent temperature sensitivity in both organic solvents and water-based solutions. Methods of preparing the Mn2+-doped quantum dots are provided. The Mn2+-doped quantum dots may be prepared via a stepwise procedure using air-stable and inexpensive chemicals. The use of air-stable chemicals can significantly reduce the cost of synthesis, chemical storage, and the risk associated with handling flammable chemicals. Methods of temperature sensing using Mn2+-doped quantum dots are provided. The stepwise procedure provides the ability to tune the temperature-sensing properties to satisfy specific needs for temperature sensing applications. Water solubility may be achieved by passivating the Mn2+-doped quantum dots, allowing the Mn2+-doped quantum dots to probe the fluctuations of local temperature in biological environments. |
FILED | Thursday, October 18, 2012 |
APPL NO | 14/352610 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/89 (20130101) C01P 2004/04 (20130101) C01P 2004/64 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/562 (20130101) C09K 11/565 (20130101) C09K 11/883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 33/588 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2991 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696492 | Cox et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Peter Thomas Rakich (New Haven, Connecticut); Heedeuk Shin (New Haven, Connecticut); Zheng Wang (Austin, Texas) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Jonathan Albert Cox (Albuquerque, New Mexico); Robert L. Jarecki, Jr. (Albuquerque, New Mexico); Peter Thomas Rakich (New Haven, Connecticut); Zheng Wang (Austin, Texas); Heedeuk Shin (New Haven, Connecticut); Aleem Siddiqui (Albuquerque, New Mexico); Andrew Lea Starbuck (Albuquerque, New Mexico) |
ABSTRACT | A radio-frequency photonic devices employs photon-phonon coupling for information transfer. The device includes a membrane in which a two-dimensionally periodic phononic crystal (PnC) structure is patterned. The device also includes at least a first optical waveguide embedded in the membrane. At least a first line-defect region interrupts the PnC structure. The first optical waveguide is embedded within the line-defect region. |
FILED | Thursday, March 03, 2016 |
APPL NO | 15/060388 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) G02B 6/1225 (20130101) Original (OR) Class G02B 2006/12061 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696517 | Gubeli, III et al. |
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FUNDED BY |
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APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
ASSIGNEE(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
INVENTOR(S) | Joseph F. Gubeli, III (Gloucester, Virginia); Michelle D. Shinn (Newport News, Virginia); Michael E. Bevins (Windsor, Virginia); Lawrence Dillon-Townes (Newport News, Virginia); George R. Neil (Williamsburg, Virginia) |
ABSTRACT | The present invention discloses a device and a method for inserting and positioning a target within a free electron laser, particle accelerator, or other such device that generates or utilizes a beam of energy or particles. The system includes a three-point registration mechanism that insures angular and translational accuracy and repeatability of positioning upon multiple insertions within the same structure. |
FILED | Wednesday, March 18, 2015 |
APPL NO | 14/662047 |
ART UNIT | 3631 — Static Structures, Supports and Furniture |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/182 (20130101) G02B 7/1825 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696699 | Cheng |
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FUNDED BY |
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APPLICANT(S) | GENERAL CYBERNATION GROUP, INC. (Rancho Cordova, California) |
ASSIGNEE(S) | CYBOMEDICAL, INC. (Rancho Cordova, California) |
INVENTOR(S) | George Shu-Xing Cheng (Folsom, California) |
ABSTRACT | A Self-Organizing Process Control Architecture is introduced with a Sensing Layer, Control Layer, Actuation Layer, Process Layer, as well as Self-Organizing Sensors (SOS) and Self-Organizing Actuators (SOA). A Self-Organizing Sensor for a process variable with one or multiple input variables is disclosed. An artificial neural network (ANN) based dynamic modeling mechanism as part of the Self-Organizing Sensor is described. As a case example, a Self-Organizing Soft-Sensor for CFB Boiler Bed Height is presented. Also provided is a method to develop a Self-Organizing Sensor. |
FILED | Friday, November 15, 2013 |
APPL NO | 14/082059 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/048 (20130101) G05B 15/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697978 | Jensen |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Aaron Jensen (Boulder Creek, California) |
ABSTRACT | A multi-frequency klystron has an electron gun which generates a beam, a circuit of bunch-align-collect (BAC) tuned cavities that bunch the beam and amplify an RF signal, a collector where the beam is collected and dumped, and a standard output cavity and waveguide coupled to a window to output RF power at a fundamental mode to an external load. In addition, the klystron has additional bunch-align-collect (BAC) cavities tuned to a higher harmonic frequency, and a harmonic output cavity and waveguide coupled via a window to an additional external load. |
FILED | Monday, June 13, 2016 |
APPL NO | 15/181239 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 23/38 (20130101) H01J 23/207 (20130101) H01J 25/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697982 | Baryshev et al. |
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FUNDED BY |
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APPLICANT(S) | Euclid TechLabs, LLC (Solon, Ohio) |
ASSIGNEE(S) | Euclid Techlabs, LLC (Solon, Ohio) |
INVENTOR(S) | Sergey V Baryshev (Lemont, Illinois); Chunguang Jing (Naperville, Illinois); Jiaqi Qiu (Willowbrook, Illinois); Sergey Antipov (Naperville, Illinois); Gwanghui Ha (Lisle, Illinois); June W Lau (Rockville, Maryland); Yimei Zhu (East Setauket, New York) |
ABSTRACT | An ElectroMagnetic-Mechanical Pulser can generate electron pulses at rates up to 50 GHz, energies up to 1 MeV, duty cycles up to 10%, and pulse widths between 100 fs and 10 ps. A modulating Transverse Deflecting Cavity (“TDC”) imposes a transverse modulation on a continuous electron beam, which is then chopped into pulses by an adjustable Chopping Collimating Aperture. Pulse dispersion due to the modulating TDC is minimized by a suppressing section comprising a plurality of additional TDC's and/or magnetic quadrupoles. In embodiments the suppression section includes a magnetic quadrupole and a TDC followed by four additional magnetic quadrupoles. The TDC's can be single-cell or triple-cell. A fundamental frequency of at least one TDC can be tuned by literally or virtually adjusting its volume. TDC's can be filled with vacuum, air, or a dielectric or ferroelectric material. Embodiments are easily switchable between passive, continuous mode and active pulsed mode. |
FILED | Wednesday, April 06, 2016 |
APPL NO | 15/091639 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) Original (OR) Class H01J 37/1472 (20130101) H01J 2237/04 (20130101) H01J 2237/061 (20130101) H01J 2237/1508 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698448 | Burrell et al. |
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FUNDED BY |
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APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Anthony K. Burrell (Naperville, Illinois); Niya Sa (Downers Grove, Illinois); Danielle Lee Proffit (Lemont, Illinois); Albert Lipson (Forest Park, Illinois); Chen Liao (Willowbrook, Illinois); John T. Vaughey (Elmhurst, Illinois); Brian J. Ingram (Chicago, Illinois) |
ABSTRACT | An electrochemical cell includes a high voltage cathode configured to operate at 1.5 volts or greater; an anode including Mg0; and an electrolyte including an ether solvent and a magnesium salt; wherein: a concentration of the magnesium salt in the ether is 1 M or greater. |
FILED | Monday, April 20, 2015 |
APPL NO | 14/690961 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/485 (20130101) H01M 10/054 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698454 | Ives et al. |
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FUNDED BY |
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APPLICANT(S) | R. Lawrence Ives (San Mateo, California); Gerald Lucovsky (Cary, North Carolina); Daniel Zeller (Scottsdale, California) |
ASSIGNEE(S) | Calabazas Creek Research, Inc. (San Mateo, California) |
INVENTOR(S) | R. Lawrence Ives (San Mateo, California); Gerald Lucovsky (Cary, North Carolina); Daniel Zeller (Scottsdale, California) |
ABSTRACT | A process for forming a coating for an RF window which has improved secondary electron emission and reduced multipactor for high power RF waveguides is formed from a substrate with low loss tangent and desirable mechanical characteristics. The substrate has an RPAO deposition layer applied which oxygenates the surface of the substrate to remove carbon impurities, thereafter has an RPAN deposition layer applied to nitrogen activate the surface of the substrate, after which a TiN deposition layer is applied using Titanium tert-butoxide. The TiN deposition layer is capped with a final RPAN deposition layer of nitridation to reduce the bound oxygen in the TiN deposition layer. The resulting RF window has greatly improved titanium layer adhesion, reduced multipactor, and is able to withstand greater RF power levels than provided by the prior art. |
FILED | Tuesday, July 09, 2013 |
APPL NO | 13/937216 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698660 | Reddy et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | Patel Bhageerath Reddy (Niskayuna, New York); Ayman Mohamed Fawzi El-Refaie (Niskayuna, New York); Kum-Kang Huh (Niskayuna, New York) |
ABSTRACT | A system and method for heating ferrite permanent magnets in an electrical machine is disclosed. The permanent magnet machine includes a stator assembly and a rotor assembly, with a plurality of ferrite permanent magnets disposed within the stator assembly or the rotor assembly to generate a magnetic field that interacts with a stator magnetic field to produce a torque. A controller of the electrical machine is programmed to cause a primary field current to be applied to the stator windings to generate the stator magnetic field, so as to cause the rotor assembly to rotate relative to the stator assembly. The controller is further programmed to cause a secondary current to be applied to the stator windings to selectively generate a secondary magnetic field, the secondary magnetic field inducing eddy currents in at least one of the stator assembly and the rotor assembly to heat the ferrite permanent magnets. |
FILED | Friday, October 25, 2013 |
APPL NO | 14/063547 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Dynamo-electric Machines H02K 1/30 (20130101) H02K 1/2766 (20130101) H02K 15/12 (20130101) H02K 15/125 (20130101) H02K 21/12 (20130101) Original (OR) Class H02K 21/26 (20130101) H02K 21/44 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09699078 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Dong Chen (Scarsdale, New York); Philip Heidelberger (Cortlandt Manor, New York); Yutaka Sugawara (Eastchester, New York) |
ABSTRACT | An apparatus and method for extending the scalability and improving the partitionability of networks that contain all-to-all links for transporting packet traffic from a source endpoint to a destination endpoint with low per-endpoint (per-server) cost and a small number of hops. An all-to-all wiring in the baseline topology is decomposed into smaller all-to-all components in which each smaller all-to-all connection is replaced with star topology by using global switches. Stacking multiple copies of the star topology baseline network creates a multi-planed switching topology for transporting packet traffic. Point-to-point unified stacking method using global switch wiring methods connects multiple planes of a baseline topology by using the global switches to create a large network size with a low number of hops, i.e., low network latency. Grouped unified stacking method increases the scalability (network size) of a stacked topology. |
FILED | Tuesday, December 29, 2015 |
APPL NO | 14/982547 |
ART UNIT | 2477 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/46 (20130101) H04L 45/04 (20130101) H04L 45/583 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09699206 | Neil |
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FUNDED BY |
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APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Joshua Charles Neil (Jemez Springs, New Mexico) |
ABSTRACT | Creation of new edges in a network may be used as an indication of a potential attack on the network. Historical data of a frequency with which nodes in a network create and receive new edges may be analyzed. Baseline models of behavior among the edges in the network may be established based on the analysis of the historical data. A new edge that deviates from a respective baseline model by more than a predetermined threshold during a time window may be detected. The new edge may be flagged as potentially anomalous when the deviation from the respective baseline model is detected. Probabilities for both new and existing edges may be obtained for all edges in a path or other subgraph. The probabilities may then be combined to obtain a score for the path or other subgraph. A threshold may be obtained by calculating an empirical distribution of the scores under historical conditions. |
FILED | Friday, January 30, 2015 |
APPL NO | 14/609836 |
ART UNIT | 2498 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/002 (20130101) H04L 63/1408 (20130101) H04L 63/1425 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 2463/144 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09699881 | Biallas |
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FUNDED BY |
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APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
ASSIGNEE(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
INVENTOR(S) | George Herman Biallas (Yorktown, Virginia) |
ABSTRACT | A diaphragm flange for connecting the tubes in a particle accelerator while minimizing beamline impedance. The diaphragm flange includes an outer flange and a thin diaphragm integral with the outer flange. Bolt holes in the outer flange provide a means for bolting the diaphragm flange to an adjacent flange or beam tube having a mating bolt-hole pattern. The diaphragm flange includes a first surface for connection to the tube of a particle accelerator beamline and a second surface for connection to a CF flange. The second surface includes a recessed surface therein and a knife-edge on the recessed surface. The diaphragm includes a thickness that enables flexing of the integral diaphragm during assembly of beamline components. The knife-edge enables compression of a soft metal gasket to provide a leak-tight seal. |
FILED | Thursday, May 14, 2015 |
APPL NO | 14/711824 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 23/003 (20130101) F16L 23/18 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/22 (20130101) Original (OR) Class H05H 2007/222 (20130101) H05H 2007/225 (20130101) H05H 2007/227 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 09693894 | Tai et al. |
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FUNDED BY |
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APPLICANT(S) | Yu-Chong Tai (Pasadena, California); Mark Humayun (Glendale, California); Jason Shih (Yorba Linda, California) |
ASSIGNEE(S) | THE UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Yu-Chong Tai (Pasadena, California); Mark Humayun (Glendale, California); Jason Shih (Yorba Linda, California) |
ABSTRACT | Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. The cannula is shaped to facilitate insertion thereof into a patient's eyeball. |
FILED | Tuesday, June 03, 2014 |
APPL NO | 14/295102 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/0097 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/155 (20130101) A61M 5/14276 (20130101) A61M 5/14593 (20130101) A61M 5/16877 (20130101) A61M 5/16881 (20130101) A61M 37/00 (20130101) A61M 2005/14204 (20130101) A61M 2205/0244 (20130101) A61M 2205/3507 (20130101) A61M 2207/00 (20130101) A61M 2210/0612 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00119 (20130101) B81C 2201/019 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/043 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 99/0001 (20130101) F16K 99/0005 (20130101) F16K 99/0034 (20130101) F16K 99/0057 (20130101) F16K 2099/008 (20130101) F16K 2099/0088 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49236 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09693957 | Lin et al. |
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FUNDED BY |
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APPLICANT(S) | Wenbin Lin (Chapel Hill, North Carolina); Demin Liu (Carrboro, North Carolina); Joseph Della Rocca (Chapel Hill, North Carolina); Stephanie A. Kramer (Chapel Hill, North Carolina); Christopher Y. Poon (Carrboro, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Wenbin Lin (Chapel Hill, North Carolina); Demin Liu (Carrboro, North Carolina); Joseph Della Rocca (Chapel Hill, North Carolina); Stephanie A. Kramer (Chapel Hill, North Carolina); Christopher Y. Poon (Carrboro, North Carolina) |
ABSTRACT | Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents. |
FILED | Monday, July 09, 2012 |
APPL NO | 14/131575 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/0019 (20130101) A61K 9/127 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 9/5123 (20130101) A61K 9/5146 (20130101) A61K 31/663 (20130101) A61K 31/675 (20130101) A61K 47/48884 (20130101) A61K 49/00 (20130101) A61K 51/1244 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694074 | Cunin et al. |
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FUNDED BY |
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APPLICANT(S) | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Paris, France); UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (Montpellier, France); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER (Montpellier, France) |
ASSIGNEE(S) | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Paris, France); UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (Montpellier, France); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER (Montpellier, France) |
INVENTOR(S) | Frederique Cunin (Montpellier, France); Jean-Olivier Durand (Palavas-les-Flots, France); Michael J. Sailor (La Jolla, California); Marcel Garcia (Prades-le-Lez, France); Emilie Secret (Montpellier, France); Magali Gary-Bobo (Castelnau-le-Lez, France); Marie Maynadier (Ceyras, France); Alain Morere (Saint-Gely du Fesc, France) |
ABSTRACT | Disclosed are nanovectors of formula (I) that can be used simultaneously for the targeting, imaging and treatment, by photodynamic therapy, of cancer cells, and to biodegradable silicon nanoparticles containing a variety of photosensitizing molecules, in particular porphyrins, capable of targeting diseased cells and inducing cell death by excitation in the near-infrared region (>600 nm) in monophotonic and biphotonic modes. In formula (I), (AA) is a porous silicon nanoparticle. |
FILED | Tuesday, March 26, 2013 |
APPL NO | 14/388860 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/28 (20130101) A61K 31/315 (20130101) A61K 31/409 (20130101) A61K 41/008 (20130101) A61K 41/0071 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 47/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09694518 | Kotov et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents Of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Nicholas A. Kotov (Ypsilanti, Michigan); Kyoung G. Lee (Ann Arbor, Michigan); Terry Shyu (Ann Arbor, Michigan); Byeong Il Kim (Ann Arbor, Michigan); Bong Gill Choi (Ann Arbor, Michigan); Seok Jae Lee (Yuseong-gu, South Korea) |
ABSTRACT | Disclosed are articles having authentication features, as well as methods for authenticating such articles by forming authentication features to prevent or diminish counterfeiting activities. A surface of an article to be authenticated (or a surface of a component associated with the article) may have a region with a periodic array of nanopillars comprising a polymeric material formed thereon. The array of nanopillars thus defines an authentication feature (e.g., a graphic image or other pattern). In certain aspects, the authentication feature may be substantially invisible to the human eye under normal conditions, but revealed when condensate is created on the surface by exposure to moisture or vapor (e.g., human breath). The methods of forming nanopillar arrays disclosed herein are simple and permit single-step replication with high fidelity. Furthermore, the methods may be used with a variety of substrates, including fabric, textiles, leather, glass, paper, and metals by way of non-limiting example. |
FILED | Monday, June 22, 2015 |
APPL NO | 14/746257 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 37/0053 (20130101) B29C 41/08 (20130101) Original (OR) Class B29C 41/20 (20130101) B29C 2035/0827 (20130101) B29C 2035/0833 (20130101) B29C 2059/023 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/744 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/00 (20141001) B42D 25/45 (20141001) Technical Subjects Covered by Former US Classification Y10T 428/2481 (20150115) Y10T 428/24893 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695223 | Alper et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Hal Alper (Austin, Texas); Eric Young (Arlington, Massachusetts); Sunmi Lee (Austin, Texas) |
ABSTRACT | Provided herein are compositions and methods useful for reducing glucose inhibition in transporting xylose, arabinose and other monosaccharides, into a yeast cell. |
FILED | Thursday, May 21, 2015 |
APPL NO | 14/719206 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/33 (20130101) C07K 14/40 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695275 | Cheng |
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FUNDED BY |
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APPLICANT(S) | THE UNIVERSITY OF AKRON (Akron, Ohio) |
ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
INVENTOR(S) | Gang Cheng (Fairlawn, Ohio) |
ABSTRACT | The present invention is directed to a versatile and high performance zwitterionic CP platform, which integrates all desired functions into one material. This zwitterionic CP consists of the conducting backbone and multifunctional zwitterionic side chains. Non-conducting zwitterionic materials gain electronic conductivity through the conducting backbone and CPs obtain excellent biocompatibility, sensitivity to environmental stimuli and controllable antifouling properties via multifunctional zwitterionic side chains. Unique properties from two distinct materials (conducting materials and zwitterionic materials) are integrated into one material without sacrificing any properties. This platform can potentially be adapted for a range of applications (e.g. bioelectronics, tissue engineering, wound healing, robotic prostheses, biofuel cell, etc.), which all require high performance conducting materials with excellent antifouling/biocompatibility at complex biointerfaces. This conducting material platform will significantly advance the development of conducting polymers in the field of biomedicine and biotechnology. |
FILED | Thursday, October 09, 2014 |
APPL NO | 15/028040 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/126 (20130101) Original (OR) Class C08G 2261/43 (20130101) C08G 2261/94 (20130101) C08G 2261/143 (20130101) C08G 2261/514 (20130101) C08G 2261/1644 (20130101) C08G 2261/3223 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695390 | Weitz et al. |
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FUNDED BY |
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APPLICANT(S) | David A. Weitz (Bolton, Massachusetts); Thomas Franke (Augsburg, Germany); Achim Wixforth (Munich, Germany); Lothar Schmid (Augsburg, Germany); Jeremy Agresti (Richmond, California); Adam R. Abate (San Francisco, California) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Universität Augsburg (Augsburg, Germany) |
INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Thomas Franke (Augsburg, Germany); Achim Wixforth (Munich, Germany); Lothar Schmid (Augsburg, Germany); Jeremy Agresti (Richmond, California); Adam R. Abate (San Francisco, California) |
ABSTRACT | Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one set of embodiments, droplets may be sorted using surface acoustic waves. The droplets may contain cells or other species. In some cases, the surface acoustic waves may be created using a surface acoustic wave generator such as an interdigitated transducer, and/or a material such as a piezoelectric substrate. The piezoelectric substrate may be isolated from the microfluidic substrate except at or proximate the location where the droplets are sorted, e.g., into first or second microfluidic channels. At such locations, the microfluidic substrate may be coupled to the piezoelectric substrate (or other material) by one or more coupling regions. In some cases, relatively high sorting rates may be achieved, e.g., at rates of at least about 1,000 Hz, at least about 10,000 Hz, or at least about 100,000 Hz, and in some embodiments, with high cell viability after sorting. |
FILED | Tuesday, August 23, 2011 |
APPL NO | 13/818146 |
ART UNIT | 1677 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2400/0421 (20130101) B01L 2400/0436 (20130101) B01L 2400/0487 (20130101) B01L 2400/0496 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 47/04 (20130101) Pipe-line Systems; Pipe-lines F17D 3/01 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0391 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696138 | Wan et al. |
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FUNDED BY |
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APPLICANT(S) | Xiaoke Wan (Herndon, Virginia); Jian Ge (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Xiaoke Wan (Herndon, Virginia); Jian Ge (Gainesville, Florida) |
ABSTRACT | A scanning monochromatic spatial low-coherent interferometer (S-LCI) can be used to simultaneously measure geometric thickness and refractive index. The probe beam of the scanning S-LCI can be an off-axis converging single wavelength laser beam, and the decomposed incident angles of the beam on the sample can be accurately defined in the Fourier domain. The angle dependent phase shift of a plane parallel plate or other sample can be obtained in a single system measurement. From the angle dependent phase shift, the geometric thickness and refractive index of the sample can be simultaneously obtained. Additionally or alternatively, the S-LCI system can interrogate the sample to profile the location and refractive index of one or more layers within the sample using the disclosed techniques. |
FILED | Tuesday, July 31, 2012 |
APPL NO | 14/236613 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0207 (20130101) G01B 9/0209 (20130101) G01B 9/02021 (20130101) G01B 9/02022 (20130101) G01B 9/02027 (20130101) G01B 11/06 (20130101) Original (OR) Class G01B 11/0675 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/45 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696304 | Wu et al. |
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FUNDED BY |
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APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
INVENTOR(S) | Jie Wu (Knoxville, Tennessee); Shigetoshi Eda (Knoxville, Tennessee) |
ABSTRACT | Methods are described for detecting pathogens, infectious diseases, and physiological conditions by quantifying change of impedance over time of when a biological sample is applied onto a lab-on-a-chip. The lab-on-a-chip utilizes alternating-current electrokinetic (ACEK) phenomena such that molecules move or are carried in an electric field generated by the application of an electrical signal of predetermined magnitude and frequency to an electrode array of the lab-on-a-chip. |
FILED | Wednesday, December 28, 2016 |
APPL NO | 15/392412 |
ART UNIT | 1677 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/021 (20130101) G01N 33/5438 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696729 | Ismagilov et al. |
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FUNDED BY |
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APPLICANT(S) | University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Rustem F. Ismagilov (Chicago, Illinois); Bo Zheng (Chicago, Illinois); Cory John Gerdts (Chicago, Illinois) |
ABSTRACT | The present invention provides microfluidic technology enabling rapid and economical manipulation of reactions on the femtoliter to microliter scale. |
FILED | Tuesday, December 22, 2015 |
APPL NO | 14/978341 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/0471 (20130101) B01F 13/0071 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/0059 (20130101) B01J 2219/00522 (20130101) B01J 2219/00585 (20130101) B01J 2219/00599 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0293 (20130101) B01L 3/502746 (20130101) B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) B01L 2300/0838 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 35/08 (20130101) G01N 2035/1034 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0694 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697338 | Eiler et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California); Thermo Fisher Scientific (Bremen) GmbH (Bremen, Germany) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THERMO FISHER SCIENTIFIC (BREMEN) GMBH (, Germany) |
INVENTOR(S) | John M. Eiler (Pasadena, California); Johannes Schwieters (Ganderkesee, Germany) |
ABSTRACT | A mass spectrometer including an entrance slit, an energy filter, a momentum filter and a detector array, the entrance slit, energy filter and momentum filter being configured to provide molecular analyte ions to the detector array at a mass resolution of about 20,000 or greater. A method for determining the isotopic composition of an analyte in a sample includes converting the analyte to molecular analyte ions, separating the molecular analyte ions using an entrance slit, separating the molecular analyte ions according to their energy levels, separating the molecular analyte ions according to their momenta, detecting two or more of the molecular analyte ions at a mass resolution of about 20,000 or greater to produce molecular analyte ion data; and analyzing the molecular analyte data to determine the isotopic composition of at least a portion of the analyte. |
FILED | Friday, October 19, 2012 |
APPL NO | 13/656447 |
ART UNIT | 2863 — Printing/Measuring and Testing |
CURRENT CPC | Electric Digital Data Processing G06F 19/703 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697647 | Kamat et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Vineet R. Kamat (Ann Arbor, Michigan); Suyang Dong (Ann Arbor, Michigan) |
ABSTRACT | A method of blending at least one virtual construction jobsite object and at least one real construction jobsite object in a dynamic augmented reality scene of a construction jobsite includes several steps. One step involves capturing a depth map image via a depth sensing device, and capturing a red, green, and blue (RGB) image via an RGB image-capturing device. Another step involves registering the depth map image and the RGB image to a common coordinate system. Yet another step involves projecting the at least one virtual construction jobsite object in a scene of the construction jobsite with the use of geographical information system (GIS) data, computer-aided design (CAD) data, or both types of data, to generate the augmented reality scene of the construction jobsite. And yet another step involves removing hidden surfaces of the at least one virtual construction jobsite object in the augmented reality scene. |
FILED | Tuesday, April 28, 2015 |
APPL NO | 14/698544 |
ART UNIT | 2673 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Image Data Processing or Generation, in General G06T 19/006 (20130101) Original (OR) Class G06T 2200/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698283 | Hardin et al. |
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FUNDED BY |
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APPLICANT(S) | Plant PV (Oakland, California) |
ASSIGNEE(S) | PLANT PV, Inc. (Alameda, California) |
INVENTOR(S) | Brian E. Hardin (Berkeley, California); Stephen T. Connor (San Francisco, California); James Randy Groves (Sunnyvale, California); Craig H. Peters (Oakland, California) |
ABSTRACT | Materials and methods for fabrication of rear tabbing, front busbar, and fine grid line layers for silicon based photovoltaic cells are disclosed. Materials include conductive metallization pastes that contain core-shell nickel based particles. |
FILED | Friday, June 20, 2014 |
APPL NO | 14/311239 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/068 (20130101) H01L 31/022425 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698286 | Ravikumar et al. |
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FUNDED BY |
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APPLICANT(S) | Arvind Ravikumar (Princeton, New Jersey); Claire Gmachl (Princeton, New Jersey); Aidong Shen (Rego Park, New York); Maria Tamargo (Teaneck, New Jersey) |
ASSIGNEE(S) | THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (New York, New York); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | Arvind Ravikumar (Princeton, New Jersey); Claire Gmachl (Princeton, New Jersey); Aidong Shen (Rego Park, New York); Maria Tamargo (Teaneck, New Jersey) |
ABSTRACT | A quantum well infrared photodetector (QWIP) and method of making is disclosed. The QWIP includes a plurality of epi-layers formed into multiple periods of quantum wells, each of the quantum wells being separated by a barrier, the quantum wells and barriers being formed of II-VI semiconductor materials. A multiple wavelength QWIP is also disclosed and includes a plurality of QWIPs stacked onto a single epitaxial structure, in which the different QWIPs are designed to respond at different wavelengths. A dual wavelength QWIP is also disclosed and includes two QWIPs stacked onto a single epitaxial structure, in which one QWIP is designed to respond at 10 μm and the other at 3-5 μm wavelengths. |
FILED | Thursday, February 20, 2014 |
APPL NO | 14/185404 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1013 (20130101) H01L 31/1832 (20130101) H01L 31/1836 (20130101) H01L 31/02966 (20130101) Original (OR) Class H01L 31/035236 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698359 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents, Acting for and on Behalf of Arizona State University (Scottsdale, Arizona) |
ASSIGNEE(S) | ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
INVENTOR(S) | Jian Li (Tempe, Arizona); Eric Turner (Phoenix, Arizona) |
ABSTRACT | Platinum and palladium complexes are disclosed that can be useful as narrow band phosphorescent emitters. Also disclosed are methods for preparing and using the platinum and palladium complexes. |
FILED | Friday, January 15, 2016 |
APPL NO | 14/996522 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0086 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/185 (20130101) C09K 2211/1044 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0087 (20130101) Original (OR) Class H01L 51/5016 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698708 | Wang |
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FUNDED BY |
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APPLICANT(S) | Joseph Wang (San Diego, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Joseph Wang (San Diego, California) |
ABSTRACT | Techniques and systems are disclosed for locomoting fuel-free nanomotors in a fluid. In one aspect of the disclosed technology, a system for locomoting fuel-free nanomotors can include an electrically-driven nanowire diode formed of two or more segments of different electrically conducting materials, a fluid container, and a mechanism that produces an electric field to drive the nanowire diode to locomote in the fluid. In another aspect, a system for locomoting fuel-free nanomotors can include a magnetically-propelled multi-segment nanowire motor formed of a magnetic segment and a flexible joint segment, a fluid container, and a mechanism that generates and controls a magnetic field to drive the multi-segment nanowire motor to locomote in the fluid. The disclosed fuel-free nanomotors can obviate fuel requirements and can be implemented for practical in vitro and in vivo biomedical applications. |
FILED | Wednesday, September 28, 2011 |
APPL NO | 13/876470 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 1/00 (20130101) B82B 1/002 (20130101) B82B 3/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/872 (20130101) H01L 43/12 (20130101) Dynamo-electric Machines H02K 35/00 (20130101) Electric Machines Not Otherwise Provided for H02N 11/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 09695066 | MacCallum et al. |
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FUNDED BY |
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APPLICANT(S) | Paragon Space Development Corporation (Tucson, Arizona) |
ASSIGNEE(S) | Paragon Space Development Corporation (Tucson, Arizona) |
INVENTOR(S) | Taber K. MacCallum (Tucson, Arizona); Laura Katrina Kelsey (Tucson, Arizona) |
ABSTRACT | This disclosure provides water processing apparatuses, systems, and methods for recovering water from wastewater such as urine. The water processing apparatuses, systems, and methods can utilize membrane technology for extracting purified water in a single step. A containment unit can include an ionomer membrane, such as Nafion®, over a hydrophobic microporous membrane, such as polytetrafluoroethylene (PTFE). The containment unit can be filled with wastewater, and the hydrophobic microporous membrane can be impermeable to liquids and solids of the wastewater but permeable to gases and vapors of the wastewater, and the ionomer membrane can be permeable to water vapor but impermeable to one or more contaminants of the gases and vapors. The containment unit can be exposed to a dry purge gas to maintain a water vapor partial pressure differential to drive permeation of the water vapor, and the water vapor can be collected and processed into potable water. |
FILED | Thursday, November 03, 2016 |
APPL NO | 15/343150 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 61/362 (20130101) B01D 61/364 (20130101) B01D 61/366 (20130101) B01D 63/10 (20130101) B01D 63/082 (20130101) B01D 69/12 (20130101) B01D 71/32 (20130101) B01D 71/36 (20130101) B01D 2311/13 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/447 (20130101) C02F 1/448 (20130101) Original (OR) Class C02F 2101/16 (20130101) C02F 2103/002 (20130101) C02F 2103/005 (20130101) C02F 2103/08 (20130101) C02F 2201/001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695531 | Sauti et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Godfrey Sauti (Hampton, Virginia); Jae-Woo Kim (Newport News, Virginia); Emilie J. Siochi (Newport News, Virginia); Kristopher E. Wise (Poquoson, Virginia) |
ABSTRACT | Consolidated carbon nanotube or graphene yarns and woven sheets are consolidated through the formation of a carbon binder formed from the dehydration of sucrose. The resulting materials, on a macro-scale are lightweight and of a high specific modulus and/or strength. Sucrose is relatively inexpensive and readily available, and the process is therefore cost-effective. |
FILED | Wednesday, March 12, 2014 |
APPL NO | 14/206292 |
ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 15/10 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 55/005 (20130101) B29C 70/12 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2005/00 (20130101) B29K 2105/162 (20130101) B29K 2105/167 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0253 (20130101) C01B 31/0273 (20130101) C01B 31/0484 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/24 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 15/00 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/64 (20130101) D04H 1/74 (20130101) D04H 1/587 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) Y10T 442/3049 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696283 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | Aerodyne Research, Inc. (Billerica, Massachusetts) |
ASSIGNEE(S) | Aerodyne Research, Inc. (Billerica, Massachusetts) |
INVENTOR(S) | Zhenhong Yu (Arlington, Massachusetts); Paul L. Kebabian (Billerica, Massachusetts); William Brown (Billerica, Massachusetts); James Assif (Billerica, Massachusetts) |
ABSTRACT | In one embodiment, a photoacoustic effect measurement instrument for measuring a species (e.g., a species of PM) in a gas employs a pair of differential acoustic cells including a sample cell that receives sample gas including the species, and a reference cell that receives a filtered version of the sample gas from which the species has been substantially removed. An excitation light source provides an amplitude modulated beam to each of the acoustic cells. An array of multiple microphones is mounted to each of the differential acoustic cells, and measures an acoustic wave generated in the respective acoustic cell by absorption of light by sample gas therein to produce a respective signal. The microphones are isolated from sample gas internal to the acoustic cell by a film. A preamplifier determines a differential signal and a controller calculates concentration of the species based on the differential signal. |
FILED | Tuesday, October 11, 2016 |
APPL NO | 15/290706 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/02 (20130101) G01N 29/2418 (20130101) Original (OR) Class G01N 2291/021 (20130101) G01N 2291/103 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696411 | McGlone |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Thomas D. McGlone (Williamsburg, Virginia) |
ABSTRACT | The system and method for multi-wavelength optical signal detection enables the detection of optical signal levels significantly below those processed at the discrete circuit level by the use of mixed-signal processing methods implemented with integrated circuit technologies. The present invention is configured to detect and process small signals, which enables the reduction of the optical power required to stimulate detection networks, and lowers the required laser power to make specific measurements. The present invention provides an adaptation of active pixel networks combined with mixed-signal processing methods to provide an integer representation of the received signal as an output. The present invention also provides multi-wavelength laser detection circuits for use in various systems, such as a differential absorption light detection and ranging system. |
FILED | Thursday, January 08, 2015 |
APPL NO | 14/592272 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4816 (20130101) Original (OR) Class G01S 7/4861 (20130101) G01S 7/4913 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/167 (20130101) H01L 31/02019 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696426 | Zuk et al. |
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FUNDED BY |
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APPLICANT(S) | Michigan Aerospace Corporation (Ann Arbor, Michigan) |
ASSIGNEE(S) | Michigan Aerospace Corporation (Ann Arbor, Michigan) |
INVENTOR(S) | David M. Zuk (Ann Arbor, Michigan); Scott Lindemann (Ann arbor, Michigan) |
ABSTRACT | A system for scanning light to define a range gated signal includes a pulsed coherent light source that directs light into the atmosphere, a light gathering instrument that receives the light modified by atmospheric backscatter and transfers the light onto an image plane, a scanner that scans collimated light from the image plane to form a range gated signal from the light modified by atmospheric backscatter, a control circuit that coordinates timing of a scan rate of the scanner and a pulse rate of the pulsed coherent light source so that the range gated signal is formed according to a desired range gate, an optical device onto which an image of the range gated signal is scanned, and an interferometer to which the image of the range gated signal is directed by the optical device. The interferometer is configured to modify the image according to a desired analysis. |
FILED | Monday, March 18, 2013 |
APPL NO | 14/397950 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4817 (20130101) G01S 7/4818 (20130101) G01S 17/95 (20130101) G01S 17/107 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 09696283 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | Aerodyne Research, Inc. (Billerica, Massachusetts) |
ASSIGNEE(S) | Aerodyne Research, Inc. (Billerica, Massachusetts) |
INVENTOR(S) | Zhenhong Yu (Arlington, Massachusetts); Paul L. Kebabian (Billerica, Massachusetts); William Brown (Billerica, Massachusetts); James Assif (Billerica, Massachusetts) |
ABSTRACT | In one embodiment, a photoacoustic effect measurement instrument for measuring a species (e.g., a species of PM) in a gas employs a pair of differential acoustic cells including a sample cell that receives sample gas including the species, and a reference cell that receives a filtered version of the sample gas from which the species has been substantially removed. An excitation light source provides an amplitude modulated beam to each of the acoustic cells. An array of multiple microphones is mounted to each of the differential acoustic cells, and measures an acoustic wave generated in the respective acoustic cell by absorption of light by sample gas therein to produce a respective signal. The microphones are isolated from sample gas internal to the acoustic cell by a film. A preamplifier determines a differential signal and a controller calculates concentration of the species based on the differential signal. |
FILED | Tuesday, October 11, 2016 |
APPL NO | 15/290706 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/02 (20130101) G01N 29/2418 (20130101) Original (OR) Class G01N 2291/021 (20130101) G01N 2291/103 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696426 | Zuk et al. |
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FUNDED BY |
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APPLICANT(S) | Michigan Aerospace Corporation (Ann Arbor, Michigan) |
ASSIGNEE(S) | Michigan Aerospace Corporation (Ann Arbor, Michigan) |
INVENTOR(S) | David M. Zuk (Ann Arbor, Michigan); Scott Lindemann (Ann arbor, Michigan) |
ABSTRACT | A system for scanning light to define a range gated signal includes a pulsed coherent light source that directs light into the atmosphere, a light gathering instrument that receives the light modified by atmospheric backscatter and transfers the light onto an image plane, a scanner that scans collimated light from the image plane to form a range gated signal from the light modified by atmospheric backscatter, a control circuit that coordinates timing of a scan rate of the scanner and a pulse rate of the pulsed coherent light source so that the range gated signal is formed according to a desired range gate, an optical device onto which an image of the range gated signal is scanned, and an interferometer to which the image of the range gated signal is directed by the optical device. The interferometer is configured to modify the image according to a desired analysis. |
FILED | Monday, March 18, 2013 |
APPL NO | 14/397950 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4817 (20130101) G01S 7/4818 (20130101) G01S 17/95 (20130101) G01S 17/107 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696699 | Cheng |
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FUNDED BY |
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APPLICANT(S) | GENERAL CYBERNATION GROUP, INC. (Rancho Cordova, California) |
ASSIGNEE(S) | CYBOMEDICAL, INC. (Rancho Cordova, California) |
INVENTOR(S) | George Shu-Xing Cheng (Folsom, California) |
ABSTRACT | A Self-Organizing Process Control Architecture is introduced with a Sensing Layer, Control Layer, Actuation Layer, Process Layer, as well as Self-Organizing Sensors (SOS) and Self-Organizing Actuators (SOA). A Self-Organizing Sensor for a process variable with one or multiple input variables is disclosed. An artificial neural network (ANN) based dynamic modeling mechanism as part of the Self-Organizing Sensor is described. As a case example, a Self-Organizing Soft-Sensor for CFB Boiler Bed Height is presented. Also provided is a method to develop a Self-Organizing Sensor. |
FILED | Friday, November 15, 2013 |
APPL NO | 14/082059 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/048 (20130101) G05B 15/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09697982 | Baryshev et al. |
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FUNDED BY |
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APPLICANT(S) | Euclid TechLabs, LLC (Solon, Ohio) |
ASSIGNEE(S) | Euclid Techlabs, LLC (Solon, Ohio) |
INVENTOR(S) | Sergey V Baryshev (Lemont, Illinois); Chunguang Jing (Naperville, Illinois); Jiaqi Qiu (Willowbrook, Illinois); Sergey Antipov (Naperville, Illinois); Gwanghui Ha (Lisle, Illinois); June W Lau (Rockville, Maryland); Yimei Zhu (East Setauket, New York) |
ABSTRACT | An ElectroMagnetic-Mechanical Pulser can generate electron pulses at rates up to 50 GHz, energies up to 1 MeV, duty cycles up to 10%, and pulse widths between 100 fs and 10 ps. A modulating Transverse Deflecting Cavity (“TDC”) imposes a transverse modulation on a continuous electron beam, which is then chopped into pulses by an adjustable Chopping Collimating Aperture. Pulse dispersion due to the modulating TDC is minimized by a suppressing section comprising a plurality of additional TDC's and/or magnetic quadrupoles. In embodiments the suppression section includes a magnetic quadrupole and a TDC followed by four additional magnetic quadrupoles. The TDC's can be single-cell or triple-cell. A fundamental frequency of at least one TDC can be tuned by literally or virtually adjusting its volume. TDC's can be filled with vacuum, air, or a dielectric or ferroelectric material. Embodiments are easily switchable between passive, continuous mode and active pulsed mode. |
FILED | Wednesday, April 06, 2016 |
APPL NO | 15/091639 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) Original (OR) Class H01J 37/1472 (20130101) H01J 2237/04 (20130101) H01J 2237/061 (20130101) H01J 2237/1508 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09698283 | Hardin et al. |
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FUNDED BY |
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APPLICANT(S) | Plant PV (Oakland, California) |
ASSIGNEE(S) | PLANT PV, Inc. (Alameda, California) |
INVENTOR(S) | Brian E. Hardin (Berkeley, California); Stephen T. Connor (San Francisco, California); James Randy Groves (Sunnyvale, California); Craig H. Peters (Oakland, California) |
ABSTRACT | Materials and methods for fabrication of rear tabbing, front busbar, and fine grid line layers for silicon based photovoltaic cells are disclosed. Materials include conductive metallization pastes that contain core-shell nickel based particles. |
FILED | Friday, June 20, 2014 |
APPL NO | 14/311239 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/068 (20130101) H01L 31/022425 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 09693557 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Aijun Zhang (Laurel, Maryland); Christina Harris (Silver Spring, Maryland); Tracy C. Leskey (Shepherdstown, West Virginia) |
ABSTRACT | Compositions (feeding deterrent/repellent for Halyomorpha halys) containing at least two compounds selected from tridecane, E-2-decenal, isolongifolanone, isolongifolenone, and at least one isolongifolenone analog having the following formula: wherein R1 is hydrogen, an oxygen, a C1-10 alcohol, aldehyde, alkyl, ether, or esters of said alcohol with a C1-10 saturated or unsaturated, straight or branched acid and R2 is hydrogen, an oxygen, a C1-10 alcohol, aldehyde, alkyl, ether, or esters of said alcohol with a C1-10 saturated or unsaturated, straight or branched acid; optionally there is a double bond between carbons 5 and 6 and R2 is hydrogen; and optionally a carrier or carrier material. Also methods for deterring feeding/repelling Halyomorpha halys involving treating an object or area with a Halyomorpha halys deterring feeding/repelling effective amount of at least one compound selected from the above compounds. |
FILED | Thursday, March 24, 2016 |
APPL NO | 15/079311 |
ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 27/00 (20130101) A01N 27/00 (20130101) A01N 35/02 (20130101) A01N 35/02 (20130101) A01N 45/02 (20130101) Original (OR) Class A01N 45/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09695450 | Browse et al. |
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FUNDED BY |
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APPLICANT(S) | Washington State University Research Foundation (Pullman, Washington) |
ASSIGNEE(S) | Washington State University (Pullman, Washington) |
INVENTOR(S) | John A. Browse (Palouse, Washington); James G. Wallis (Moscow, Idaho); Jennifer L. Watts (Moscow, Idaho) |
ABSTRACT | The amino acid and nucleic acid sequences of a Δ5-desaturase enzyme and a Δ8-desaturase enzyme are disclosed. The nucleic acid sequences can be used to design recombinant DNA constructs and vectors. These vectors can then be used to transform various organisms, including for example, plants and yeast. The transformed organisms will then produce polyunsaturated fatty acids. The amino acid sequences are useful for generating enzyme-specific antibodies that are useful for identifying the desaturases. |
FILED | Wednesday, June 18, 2014 |
APPL NO | 14/308456 |
ART UNIT | 1662 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) C12N 9/0083 (20130101) C12N 15/80 (20130101) C12N 15/85 (20130101) C12N 15/8241 (20130101) C12N 15/8247 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 09697467 | Riabov et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (White Plains, New York); Octavian Udrea (Ossining, New York) |
ABSTRACT | In at least one embodiment, a method and a system for determining a set of plans that best match a set of preferences. The method may include receiving into a goal specification interface at least one goal to be accomplished by the set of plans; receiving into a preference engine a pattern that includes preferences; generating a planning problem by using the preference engine; generating a set of plans by at least one planner; and providing the set of plans for selection of one plan to deploy. In a further embodiment, the preferences may be an occurrence or non-occurrence of at least one component, an occurrence of one component over another component, an ordering between at least two components, an existence or non-existence of at least one tag in a final stream, an existence of one tag over another tag in the final stream. |
FILED | Wednesday, May 21, 2014 |
APPL NO | 14/283945 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09699009 | Ainspan et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Herschel A. Ainspan (New Hempstead, New York); Timothy O. Dickson (Danbury, Connecticut) |
ABSTRACT | A four-level pulse amplitude modulation receiver has a four-level pulse amplitude modulation mode and a non-return-to-zero modulation mode. First, second, and third four-level pulse amplitude modulation samplers are coupled to an input. Each of the samplers has a corresponding output in turn including a corresponding binary decision of the first, second, and third samplers. A four-level pulse amplitude modulation decoder circuit has inputs coupled to the outputs of the samplers. The four-level pulse amplitude modulation decoder circuit is active in the four-level pulse amplitude modulation mode. The receiver also includes a non-return-to-zero majority voting circuit coupled to the outputs of the samplers. The non-return-to-zero majority voting circuit has an output and is configured to output a majority decision of the corresponding binary decisions of the samplers, and is active in the non-return-to-zero modulation mode. |
FILED | Thursday, June 30, 2016 |
APPL NO | 15/199037 |
ART UNIT | 2633 — Digital Communications |
CURRENT CPC | Transmission H04B 1/16 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0332 (20130101) H04L 25/4917 (20130101) Original (OR) Class H04L 27/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 09696115 | Nigro |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Michael A. Nigro (El Paso, Texas) |
ABSTRACT | A reticle for a projectile weapon aiming apparatus including a plurality of aiming marks, the plurality of aiming marks include a first mark positioned at the center of the reticle and at least one additional mark spaced below the first mark along a vertical center axis of the reticle, wherein adjacent marks of the first mark and the at least one additional mark are spaced apart by predetermined distances. First and second horizontal stripes are provided on each side of the plurality of aiming marks respectively, the first and second horizontal stripes offset relative to the vertical center axis with a gap provided therebetween and extending towards the perimeter of the reticle, the first and second horizontal stripes spaced a predetermined distance from a bottom of the reticle measured along the vertical center axis. |
FILED | Tuesday, January 26, 2016 |
APPL NO | 15/006292 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Weapon Sights; Aiming F41G 1/16 (20130101) F41G 1/30 (20130101) F41G 1/38 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 09694047 | Murray et al. |
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FUNDED BY |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Samuel S. Murray (Saugus, California); Elsa J. Murray (Saugus, California); Jeffrey Wang (Sherman Oaks, California); Keyvan Behnam (Simi Valley, California) |
ABSTRACT | The use of autogenous bone graft is the current gold standard in the 1.5 million bone-grafting surgeries performed annually in the United States. Although this practice has resulted in high rates of fusion success, it is associated with increased operative time and blood loss, along with a significant degree of donor-site morbidity. Additionally, in certain settings such as revision cases, multilevel constructs, or in patients with medical co-morbidities, autogenous bone graft may exist in limited quantity and quality. This significant need for a suitable alternative to autogenous bone graft has stimulated great interest in the exploration of bone graft substitutes and extenders. |
FILED | Tuesday, June 30, 2015 |
APPL NO | 14/755408 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/10 (20130101) A61K 38/12 (20130101) Original (OR) Class A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 38/1875 (20130101) A61K 38/1875 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
US 09696197 | Kroes |
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FUNDED BY |
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APPLICANT(S) | Daniel E. Kroes (Baton Rouge, Louisiana) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Department of the Interior (Washington, District of Columbia) |
INVENTOR(S) | Daniel E. Kroes (Baton Rouge, Louisiana) |
ABSTRACT | An automatic surface elevation table (Auto SET) for measuring ground surface movements and land surface subsidence. The Auto SET includes a free-floating foot resting on a sediment surface. A benchmark rod passes through a center of the free-floating foot, and is driven into the sediment surface and extends above the sediment surface. A water level recorder system is attached to the benchmark rod. The water level recorder system includes a water level recorder attached to a top of the benchmark rod, a double block pulley system having an upper end connected to the water level recorder and a lower end connected to the free-floating foot, and a counterweight attached to the upper end of the double block pulley system. The water level recorder system measures movement of the free-floating foot to determine ground surface movements. |
FILED | Tuesday, October 14, 2014 |
APPL NO | 14/514004 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/66 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 09694065 | Pushko et al. |
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FUNDED BY |
|
APPLICANT(S) | MEDIGEN, INC. (Frederick, Maryland) |
ASSIGNEE(S) | MEDIGEN, INC. (Frederick, Maryland) |
INVENTOR(S) | Peter Pushko (Frederick, Maryland); Irina Tretyakova (Frederick, Maryland); Igor Lukashevich (Cockeysville, Maryland) |
ABSTRACT | Described herein are i-DNA™ vectors and vaccines and methods for using the same. The i-DNA™ generates live attenuated vaccines in eukaryotic cells in vitro or in vivo for pathogenic RNA viruses, particularly chikungunya virus (CHIKV). When iDNA is injected into the vaccine recipient, RNA of live attenuated virus is generated by in vivo transcription in the recipient's tissues. This initiates production of progeny attenuated viruses in the tissues of the vaccine recipient, as well as elicitation of an effective immune response protecting against wild-type, non-attenuated virus. |
FILED | Thursday, July 02, 2015 |
APPL NO | 14/790960 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 49/0004 (20130101) A61K 2039/53 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/36121 (20130101) C12N 2770/36122 (20130101) C12N 2770/36134 (20130101) C12N 2770/36151 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09696030 | Kenney et al. |
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FUNDED BY |
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APPLICANT(S) | ALSTOM Technology Ltd (Baden, Switzerland) |
ASSIGNEE(S) | GENERAL ELECTRIC TECHNOLOGY GMBH (Baden, Switzerland) |
INVENTOR(S) | James R. Kenney (Windsor, Connecticut); Armand A. Levasseur (Windsor Locks, Connecticut); Paul J. Chapman (Windsor, Connecticut); Yen-Ming Chen (Broad Brook, Connecticut) |
ABSTRACT | A combustion system is provided for an oxy-combustion furnace. The combustion system includes at least one windbox mountable on the oxy-combustion furnace and having at least one main firing location. At least one primary inlet is positioned in the at least one main firing location for conveying fuel and the first oxidant into the oxy-combustion furnace. At least one secondary inlet is positioned in the at least one main firing location for conveying the second oxidant into the oxy-combustion furnace. The at least one secondary inlet is angularly offset from the at least one primary inlet. |
FILED | Monday, January 28, 2013 |
APPL NO | 13/751591 |
ART UNIT | 3749 — Static Structures, Supports and Furniture |
CURRENT CPC | Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 5/08 (20130101) Original (OR) Class F23C 5/12 (20130101) F23C 9/003 (20130101) Supplying Air or Non-combustible Liquids or Gases to Combustion Apparatus in General; Valves or Dampers Specially Adapted for Controlling Air Supply or Draught in Combustion Apparatus; Inducing Draught in Combustion Apparatus; Tops for Chimneys or Ventilating Shafts; Terminals for Flues F23L 7/007 (20130101) F23L 9/02 (20130101) F23L 2900/07001 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/322 (20130101) Y02E 20/344 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 04, 2017.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20170704.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page