FedInvent™ Patents

Patent Details for Tuesday, August 15, 2017

This page was updated on Monday, March 27, 2023 at 05:16 AM GMT

Department of Health and Human Services (HHS)

09730615 — Automated surface-based anatomical analysis based on atlas-based segmentation of medical imaging

US 09730615	Miller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Michael I. Miller (Towson, Maryland); Susumu Mori (Ellicott City, Maryland); Anqi Qiu (Singapore, Singapore)
ASSIGNEE(S)	THE JOHN HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Michael I. Miller (Towson, Maryland); Susumu Mori (Ellicott City, Maryland); Anqi Qiu (Singapore, Singapore)
ABSTRACT	A non-invasive imaging system, including: a non-invasive imaging scanner; a signal processing unit in communication with the imaging scanner to receive an imaging signal from a subject under observation; and a data storage unit in communication with the signal processing unit, wherein the data storage unit stores template data corresponding to a tissue region of the subject, and wherein the signal processing unit is adapted to generate a surface map to encode a property of a subvolume of the tissue region using the template data.
FILED	Tuesday, July 07, 2009
APPL NO	12/999866
ART UNIT	3737 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/103 (20130101) Original (OR) Class A61B 6/037 (20130101) A61B 6/501 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/46 (20170101) G06T 2207/10072 (20130101) G06T 2207/20068 (20130101) G06T 2207/20128 (20130101) G06T 2207/30096 (20130101)
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09730632 — Integrated sleep diagnostic and therapeutic system and method

US 09730632	Kayyali et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Hani Kayyali (Shaker Heights, Ohio); Dan Bishop (Tallmadge, Ohio); Brian M. Kolkowski (Leroy, Ohio)
ASSIGNEE(S)	Cleveland Medical Devices Inc (Cleveland, Ohio)
INVENTOR(S)	Hani Kayyali (Shaker Heights, Ohio); Dan Bishop (Tallmadge, Ohio); Brian M. Kolkowski (Leroy, Ohio)
ABSTRACT	The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself.
FILED	Tuesday, March 29, 2011
APPL NO	13/074901
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/4818 (20130101) Original (OR) Class A61B 5/4836 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/00 (20130101) A61M 16/0003 (20140204)
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09730637 — Layered particles for retrieving DNA released from cells from a gastrointestinal tract sample and methods for making and using them

US 09730637	Simberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Dmitri Simberg (San Diego, California); Yu-Tsueng Liu (San Diego, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Dmitri Simberg (San Diego, California); Yu-Tsueng Liu (San Diego, California)
ABSTRACT	In alternative embodiments, the invention provides compositions such as devices, pills, beads, capsules, products of manufacture, particles, microparticles, nanoparticles, gels, liquid gels, liquid gel capsules, capsules, tablets, geltabs, liquids, sprays, emulsions, suspensions, pastes or yogurts, for the detection and isolation of biomarkers, nucleic acids, proteins or peptides, proteoglycans, lipids, fats, sugars or polysaccharides in the gastrointestinal tract for e.g., detecting the presence of particular exogenous or endogenous nucleic acids, e.g., DNA or RNA, or proteins, in the gastrointestinal tract, for example, to diagnose the presence of an infectious or exogenous agent such as a virus, a fungus, a parasite, a bacteria, intestinal helminths and protozoan parasites, and the like, or a biomarker such as a cancer-causing or cancer-predisposing allele, e.g., mutations of the KRAS2 oncogene in pancreatic cancer. In alternative embodiments, compositions of the invention comprise magnetic particles such as a magnetically-responsive microparticle or nanoparticle; a superparamagnetic bead or polystyrene bead; a superparamagnetic fine particle; a ferrimagnetic particle; or, a magnetic microsphere, nanosphere, microbead or nanobeads. In alternative embodiments, the invention provides methods for detecting, retrieving, capturing or isolating a sample of a nucleic acid, or an anionic, cationic or hydrophobic protein or peptide, a mucin, a phosphoprotein, a proteoglycan or a polysaccharide, in vivo.
FILED	Friday, August 17, 2012
APPL NO	14/238189
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/1473 (20130101) A61B 5/4848 (20130101) A61B 5/6861 (20130101) Original (OR) Class A61B 5/14546 (20130101) A61B 10/0045 (20130101) A61B 2010/0061 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2563/143 (20130101) C12Q 2563/155 (20130101)
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09730877 — Methods for treating hair loss disorders

US 09730877	Christiano et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Angela M. Christiano (Mahwah, New Jersey); Raphael Clynes (West Nyack, New York)
ABSTRACT	The invention provides for methods for treating a hair loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of Transcription inhibitor.
FILED	Friday, August 07, 2015
APPL NO	14/821666
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/41 (20130101) A61K 8/64 (20130101) A61K 8/4953 (20130101) Original (OR) Class A61K 31/52 (20130101) A61K 31/63 (20130101) A61K 31/137 (20130101) A61K 31/277 (20130101) A61K 31/407 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/529 (20130101) A61K 31/553 (20130101) A61K 31/713 (20130101) A61K 31/5377 (20130101) A61K 31/7052 (20130101) A61K 2800/782 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 7/00 (20130101)
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09730888 — Method of enhancing delivery of therapeutic compounds to the eye

US 09730888	Pan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Wayne State University (Detroit, Michigan)
ASSIGNEE(S)	Wayne State University (Detroit, Michigan)
INVENTOR(S)	Zhuo-Hua Pan (Troy, Michigan); Elena Ivanova (White Plains, New York)
ABSTRACT	The invention provides methods for enhancing the delivery of therapeutic compounds to the eye of a subject by administering plasmin or derivatives thereof and the therapeutic compounds to the eye.
FILED	Thursday, March 13, 2014
APPL NO	14/777420
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 36/05 (20130101) A61K 38/16 (20130101) A61K 38/36 (20130101) A61K 38/484 (20130101) A61K 48/0008 (20130101) A61K 48/0075 (20130101) Enzymes C12Y 304/21007 (20130101)
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09730889 — Steroid-sparing effects of beta-adrenergic inverse agonists and uses thereof

US 09730889	Bond et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Richard A. Bond (Houston, Texas); Burton F. Dickey (Houston, Texas); Michael J. Tuvim (Houston, Texas)
ASSIGNEE(S)	University of Houston System (Houston, Texas)
INVENTOR(S)	Richard A. Bond (Houston, Texas); Burton F. Dickey (Houston, Texas); Michael J. Tuvim (Houston, Texas)
ABSTRACT	Provided herein is a pharmaceutical composition combination which comprises (a) a corticosteroid and (b) b-adrenergic receptor antagonist characterised in that active ingredients (a) and (b) form part of a single composition. Further provided is a method of treating a human or animal patient suffering from or susceptible to a respiratory disease or condition, said method comprises simultaneously, concurrently, separately or sequentially administering to the patient an effective amount of a b-adrenergic receptor antagonist and a corticosteroid.
FILED	Tuesday, May 08, 2012
APPL NO	13/466498
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0075 (20130101) Original (OR) Class A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 45/06 (20130101) A61K 47/26 (20130101) A61K 2300/00 (20130101)
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09730908 — SARMs and method of use thereof

US 09730908	Dalton et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Child Health and Human Development (NICHD) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S)	UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
INVENTOR(S)	James T. Dalton (Ann Arbor, Michigan); Duane D. Miller (Collierville, Tennessee); Thamarai Ponnusamy (Memphis, Tennessee); Ramesh Narayanan (Cordove, Tennessee)
ABSTRACT	This invention is directed to substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder such as Duchenne muscular dystrophy or Becker muscular dystrophy.
FILED	Tuesday, December 08, 2015
APPL NO	14/963054
ART UNIT	1672 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Fodder A23K 20/111 (20160501) A23K 50/10 (20160501) A23K 50/30 (20160501) A23K 50/75 (20160501) A23K 50/80 (20160501) Preparations for Medical, Dental, or Toilet Purposes A61K 31/277 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 255/60 (20130101)
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09730913 — High affinity beta lactamase inhibitors

US 09730913	Freire et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Ernesto Freire (Baltimore, Maryland); Rogelio Siles (Cockeysville, Maryland); Patrick C. Ross (College Park, Maryland)
ABSTRACT	Inhibitors of beta lactamases and their use in treating bacterial infections are disclosed.
FILED	Friday, October 12, 2012
APPL NO	14/351280
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 31/41 (20130101) Original (OR) Class A61K 31/41 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 311/13 (20130101) C07C 311/27 (20130101) Heterocyclic Compounds C07D 257/04 (20130101)
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09730917 — Desferrithiocin polyether analogues

US 09730917	Bergeron, Jr.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S)	Raymond J. Bergeron, Jr. (Gainesville, Florida)
ABSTRACT	A relatively non-toxic desazadesferrithiocin analog having the formula: wherein: R₁, R₂, R₄and R₅may be the same or different and may be H, straight or branched chain alkyl having up to 14 carbon atoms, e.g., methyl, ethyl, propyl and butyl, or arylalkyl wherein the aryl portion is hydrocarbyl and the alkyl portion is straight or branched chain, the arylalkyl group having up to 14 carbon atoms, R₂optionally being alkoxy having up to 14 carbon atoms; R₃is [(CH₂)_n—O]_x—[(CH₂)_n—O]_y-alkyl; n is, independently, an integer from 1 to 8; x is an integer from 1 to 8; y is an integer from 0 to 8, and R₃O may occupy any position on the phenyl ring except the 4-position, or a salt, hydrate or solvate thereof; and methods and compositions for treating the effects of trivalent metal, i.e., iron, overload.
FILED	Monday, October 05, 2015
APPL NO	14/875462
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) Original (OR) Class Heterocyclic Compounds C07D 277/12 (20130101)
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09730921 — Compositions and methods for the prevention and treatment of mast cell-induced vascular leakage

US 09730921	Abraham et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Soman N. Abraham (Chapel Hill, North Carolina); Ashley L. St. John (Durham, North Carolina)
ABSTRACT	Disclosed herein are methods of diagnosing and treating infectious disease characterized by a pathology that involves hemorrhaging or pathological vascular leakage.
FILED	Friday, March 15, 2013
APPL NO	14/388140
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Original (OR) Class A61K 31/55 (20130101) A61K 31/352 (20130101) A61K 31/4535 (20130101) A61K 31/4709 (20130101) A61K 38/55 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/6893 (20130101) G01N 2333/175 (20130101) G01N 2333/185 (20130101) G01N 2333/475 (20130101) G01N 2333/5412 (20130101) G01N 2333/96433 (20130101) G01N 2800/26 (20130101) G01N 2800/50 (20130101)
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09730928 — Trizol-1-OL analogs anti-retroviral latency drugs

US 09730928	Planelles et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	Univeristy of Utah Research Foundation (Salt Lake City, None)
INVENTOR(S)	Vincente Planelles (Salt Lake City, Utah); Alberto Bosque-Pardos (Salt Lake City, Utah); Chris M. Ireland (Salt Lake City, Utah); Ryan Van Wagoner (Salt Lake City, Utah); Mary Kay Harper-Ireland (Salt Lake City, Utah); John Alan Maschek (Salt Lake City, Utah)
ABSTRACT	In one aspect, the invention relates to triazol-1-ol compounds, analogs thereof, compositions comprising same, and methods of using same, alone or in combination with other agents, to reactivate latent retroviruses, and more particularly to reactivate latent HIV-1. Such compounds, compositions, and methods can be used, for example, in connection with diagnosing and/or treating a retrovirus, and more specifically HIV-1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED	Friday, June 13, 2014
APPL NO	14/896906
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/53 (20130101) A61K 31/416 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/501 (20130101) Original (OR) Class A61K 31/4192 (20130101) A61K 31/4192 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 231/54 (20130101) C07D 249/04 (20130101) C07D 249/18 (20130101) C07D 253/08 (20130101) C07D 403/04 (20130101) C07D 471/04 (20130101)
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09730935 — Targeting a non-canonical notch signaling pathway for cancer treatment

US 09730935	Lu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Bingwei Lu (Stanford, California); Kyu-Sun Lee (Daejeon, South Korea)
ABSTRACT	Methods and compositions are provided for treating an individual having cancer. Aspects of the methods include administering to the individual an inhibitor of a non-canonical Notch signaling pathway gene in an amount effective to treat the cancer. Also provided are reagents, devices and kits thereof that find use in practicing the subject methods.
FILED	Thursday, December 11, 2014
APPL NO	14/567834
ART UNIT	1674 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/5377 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101)
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09730941 — Methods and compositions for the inhibition of Pin1

US 09730941	Lu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Kun Ping Lu (Newton, Massachusetts); Matthew Brian Boxer (Rockville, Maryland); Mindy Irene Emily Davis (Rockville, Maryland); Rajan Pragani (Rockville, Maryland); Min Shen (Rockville, Maryland); Anton Momtchilov Simeonov (Rockville, Maryland); Shuo Wei (Chestnut Hill, Massachusetts); Xiao Zhen Zhou (Newton, Massachusetts)
ABSTRACT	The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels.
FILED	Friday, June 07, 2013
APPL NO	14/406401
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/185 (20130101) A61K 31/341 (20130101) A61K 31/357 (20130101) A61K 31/365 (20130101) A61K 31/381 (20130101) A61K 31/382 (20130101) A61K 31/402 (20130101) A61K 31/404 (20130101) A61K 31/405 (20130101) A61K 31/427 (20130101) A61K 31/428 (20130101) A61K 31/473 (20130101) A61K 31/473 (20130101) A61K 31/496 (20130101) A61K 31/4025 (20130101) A61K 31/4245 (20130101) A61K 31/4704 (20130101) A61K 31/5377 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101)
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09730942 — Materials and method for inhibiting replication protein A and uses thereof

US 09730942	Turchi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S)	John J. Turchi (Indianapolis, Indiana); Sarah Shuck (Nashville, Tennessee)
ABSTRACT	Targeting uncontrolled cell proliferation and resistance to DNA damaging chemotherapeutics with at least one reagent has significant potential in cancer treatment. Replication Protein A, the eukaryotic single-strand (ss) DNA binding protein, is essential for genomic maintenance and stability via roles in both DNA replication and repair. Reported herein are small molecules that inhibits the in vitro, in vivo, and cellular ssDNA binding activity of RPA, thereby disrupting the eukaryotic cell cycle, inducing cytotoxicity and increasing the efficacy of chemotherapeutic agents damage DNA, and/or disrupt its replication and/or function. These results provide new insights into the mechanism of RPA-ssDNA interactions in chromosome maintenance and stability. This represents a molecularly targeted eukaryotic DNA binding inhibitor and demonstrates the utility of targeting a protein-DNA interaction as a means of studying the cell cycle and providing a therapeutic strategy for cancer treatment.
FILED	Tuesday, January 03, 2017
APPL NO	15/396978
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/4709 (20130101) A61K 31/5377 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/26 (20130101) A61K 47/38 (20130101)
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09730960 — Method for treating or preventing graft versus host disease

US 09730960	McFadden et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Douglas G. McFadden (Gainesville, Florida); Eric C. Bartee (Gainesville, Florida); Christopher R. Cogle (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	Douglas G. McFadden (Gainesville, Florida); Eric C. Bartee (Gainesville, Florida); Christopher R. Cogle (Gainesville, Florida)
ABSTRACT	A method of treating or preventing graft versus host disease (GVHD) in a subject receiving a graft comprising hematopoietic cells is provided. The method comprises contacting the graft ex vivo with an amount of a Myxoma Virus effective to inhibit proliferation of T lymphocytes in the graft and to treat or prevent GVHD in the host subject following infusion of the graft into the subject. After the contacting of the graft with the Myxoma Virus, the method comprises transplanting the virus-treated graft into the subject.
FILED	Monday, June 11, 2012
APPL NO	14/124800
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/17 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 35/768 (20130101) A61K 2035/122 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2710/24041 (20130101)
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09730961 — Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases

US 09730961	Prockop et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Darwin J. Prockop (Philadelphia, Pennsylvania); Joo Youn Oh (Seoul, South Korea); Barry Berkowitz (Framingham, Massachusetts); Gavin W. Roddy (Rochester, Minnesota); Robert Rosa (Holland, Texas)
ASSIGNEE(S)	The Texas A and M University System (College Station, Texas); Temple Therapeutics, Inc. (Framingham, Massachusetts); Scott and White Healthcare (Temple, Texas)
INVENTOR(S)	Darwin J. Prockop (Philadelphia, Pennsylvania); Joo Youn Oh (Seoul, South Korea); Barry Berkowitz (Framingham, Massachusetts); Gavin W. Roddy (Rochester, Minnesota); Robert Rosa (Holland, Texas)
ABSTRACT	The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.
FILED	Thursday, August 13, 2015
APPL NO	14/825788
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 39/00 (20130101) A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) Peptides C07K 16/18 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 2501/25 (20130101) C12N 2501/48 (20130101)
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09730970 — Seaweed extracts, unsaturated aldehydes, and methods of treatment

US 09730970	Luesch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Smithsonian Institution (SI)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); Smithsonian Institution (Washington, District of Columbia)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); Smithsonian Institution (Washington, District of Columbia)
INVENTOR(S)	Hendrik Luesch (Gainesville, Florida); Valerie J. Paul (Fort Pierce, Florida); Ranjala Ratnayake (Gainesville, Florida)
ABSTRACT	The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated diseases and diseases mediated through the activation of the Nrf2-ARE (antioxidant response element) pathway, including proliferative diseases and disorders, Alzheimer's disease, stroke, and certain diseases and disorders of aging and associated with aging and exposure, by use of the extracts, compounds, and compositions thereof.
FILED	Friday, March 14, 2014
APPL NO	14/846544
ART UNIT	1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 36/02 (20130101) A61K 36/05 (20130101) Original (OR) Class A61K 2236/33 (20130101)
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09730975 — Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair

US 09730975	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) National Institute of Mental Health (NIMH)
APPLICANT(S)	THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Gong Chen (State College, Pennsylvania); Gang-Yi Wu (State College, Pennsylvania); Lei Zhang (State College, Pennsylvania); Jiu-Chao Yin (State College, Pennsylvania); Hana Yeh (State College, Pennsylvania); Ning-Xin Ma (State College, Pennsylvania); Grace Lee (State College, Pennsylvania)
ABSTRACT	Provided are methods and compositions from reprogramming human glial cells into human neurons. The reprogramming is achieved using combinations of compounds that can modify signaling via Transforming growth factor beta (TGF-β), Bone morphogenetic protein (BMP), glycogen synthase kinase 3 (GSK-3), and γ-secretase/Notch pathways. The reprogramming is demonstrated using groups of three or four compounds that are chosen from the group thiazovivin, LDN193189, SB431542, TTNPB, CHIR99021, DAPT, VPA, SAG, purmorphamine. Reprogramming is demonstrated using the group of LDN193189/CHIR99021/DAPT, the group of B431542/CHIR99021/DAPT, the group of LDN193189/DAPT/SB431542, the group of LDN193189/CHIR99021/SB431542, a three drug combination of SB431542/CHIR99021/DAPT. Reprogramming using functional analogs of the compounds is also provided, as are pharmaceutical formulations that contain the drug combinations.
FILED	Wednesday, November 25, 2015
APPL NO	14/951723
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4439 (20130101) A61K 38/05 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 2501/15 (20130101) C12N 2501/155 (20130101) C12N 2501/727 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/08 (20130101)
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09730977 — Inhibitors of mitochondrial fission and methods of use thereof

US 09730977	Mochly-Rosen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Daria Mochly-Rosen (Menlo Park, California); Xin Qi (Beachwood, Ohio); Nir Qvit (Menlo Park, California)
ABSTRACT	The present disclosure provides peptides and constructs that inhibit mitochondrial fission, and compositions comprising the peptides or constructs. The present disclosure provides methods of reducing abnormal mitochondrial fission in a cell. Also provided are methods for designing and validating mitochondrial fission inhibitor constructs and peptides, including but not limited to, evaluating the effects of the constructs and peptides on binding of dynamin-1-related protein (Drp1) GTPase activity, Drp1 to mitochondrial fission 1 protein (Fis1), reduction of mitochondrial damage, reduction in cell death, inhibition of mitochondrial fragmentation in a cell under pathological conditions, and reduced loss of neurites in primary dopaminergic neurons in a Parkinsonism cell culture.
FILED	Tuesday, January 05, 2016
APPL NO	14/988403
ART UNIT	1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/08 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 51/08 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/00 (20130101) C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 14/4722 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/914 (20130101) G01N 2333/4703 (20130101) G01N 2500/02 (20130101) G01N 2500/10 (20130101) G01N 2500/20 (20130101)
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09730978 — Compositions for treating dry eye disease

US 09730978	Sullivan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Regents of the University of California (Oakland, California); Schepens Eye Research Institute (Boston, Massachusetts)
ASSIGNEE(S)	Thc Regents of the University of California (Oakland, California); Schepens Eye Research Institute (Boston, Massachusetts)
INVENTOR(S)	Benjamin Sullivan (San Diego, California); Tannin A. Schmidt (Calgary, Canada); David A. Sullivan (Boston, Massachusetts)
ABSTRACT	The present invention provides a pharmaceutical composition, and methods of use thereof, for treating ocular boundary deficiency, symptoms associated therewith, or an undesired condition that is associated with or causes ocular boundary deficiency at the ocular surface. The pharmaceutical composition of the present invention comprises a human PRG4 protein, a lubricant fragment, homolog, or isoform thereof, suspended in an ophthalmically acceptable balanced salt solution. The pharmaceutical composition of the present invention may also comprise one or more ophthalmically acceptable agents selected from the group consisting of an ophthalmically acceptable demulcent, excipient, astringent, vasoconstrictor, emollient, sodium hyaluronate, hyaluronic acid, and surface active phospholipids, in a pharmaceutically acceptable carrier for topical administration.
FILED	Wednesday, April 06, 2016
APPL NO	15/091665
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 31/568 (20130101) A61K 31/568 (20130101) A61K 31/685 (20130101) A61K 31/688 (20130101) A61K 31/715 (20130101) A61K 31/728 (20130101) A61K 38/13 (20130101) A61K 38/13 (20130101) A61K 38/14 (20130101) Original (OR) Class A61K 38/17 (20130101) A61K 38/1709 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 47/24 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09730980 — Method of treating type I diabetes using apolipoprotein A-IV

US 09730980	Tso et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	University of Cincinnati (Cincinnati, Ohio)
ASSIGNEE(S)	University of Cincinnati (Cincinnati, Ohio)
INVENTOR(S)	Patrick Tso (Cincinnati, Ohio); Xiaoming Li (Cincinnati, Ohio)
ABSTRACT	Methods for treating type one diabetes mellitus in a subject in need thereof and pharmaceutical compositions for the treatment of type one diabetes mellitus are disclosed, including combination therapies with insulin. The methods include administering an effective amount of apolipoprotein A-IV to the subject having type I diabetes. The pharmaceutical composition includes apolipoprotein A-IV formulated for administration to a subject for the treatment of type one diabetes mellitus.
FILED	Thursday, July 25, 2013
APPL NO	14/416527
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) A61K 38/28 (20130101) A61K 38/1709 (20130101) Original (OR) Class Peptides C07K 14/775 (20130101)
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09730981 — Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids

US 09730981	Pan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Wayne State University (Detroit, Michigan); Salus University (Elkins Park, Pennsylvania)
ASSIGNEE(S)	Salus University (Elkins Park, Pennsylvania); Wayne State University (Detroit, Michigan)
INVENTOR(S)	Zhuo-Hua Pan (Troy, Michigan); Alexander M. Dizhoor (Dresher, Pennsylvania)
ABSTRACT	Nucleic acid vectors encoding light-gated cation-selective membrane channels, in particular channelrhodopsin-2 (Chop2), converted inner retinal neurons to photosensitive cells in photoreceptor-degenerated retina in an animal model. Such treatment restored visual perception and various aspects of vision. A method of restoring light sensitivity to a retina of a subject suffering from vision loss due to photoreceptor degeneration, as in retinitis pigmentosa or macular degeneration, is provided. The method comprises delivering to the subject by intravitreal or subretinal injection, the above nucleic acid vector which comprises an open reading frame encoding a rhodopsin, to which is operatively linked a promoter and transcriptional regulatory sequences, so that the nucleic acid is expressed in inner retinal neurons. These cells, normally light-insensitive, are converted to a light-sensitive state and transmit visual information to the brain, compensating for the loss, and leading to restoration of various visual capabilities.
FILED	Tuesday, May 21, 2013
APPL NO	13/899198
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 48/005 (20130101) Peptides C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2830/002 (20130101) C12N 2830/008 (20130101)
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09730985 — Method for reducing blood glucose

US 09730985	Ozcan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S)	Umut Ozcan (Jamaica Plains, Massachusetts); Jaemin Lee (Brookline, Massachusetts)
ABSTRACT	A method of reducing blood glucose in a subject has been developed. In preferred embodiments, the method involves administering to the subject a specific activator of endogenous mitogen-activated protein kinase kinase 6 (MKK3), mitogen-activated protein kinase kinase 6 (MKK4), mitogen-activated protein kinase kinase 6 (MKK6), p38 mitogen-activated protein kinase (p38MAPK), mitogen-activated kinase-activated protein kinase 2 (MK2), or a combination thereof, in an effective amount to reduce blood glucose in a subject. In other embodiments, the method involves administering to the subject a specific activator to increase X-box binding protein 1 (XBP1) phosphorylation on Thr48 and Ser61 in an effective amount to reduce blood glucose in the subject. Methods of identifying agents for reducing blood glucose in a subject are also provided.
FILED	Friday, October 16, 2015
APPL NO	14/885626
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/66 (20130101) A61K 38/45 (20130101) Original (OR) Class Enzymes C12Y 207/12002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/573 (20130101) G01N 2333/4703 (20130101) G01N 2440/14 (20130101) G01N 2800/042 (20130101)
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09730988 — Parasitic biological agents for treatment and prevention of graft versus host disease

US 09730988	Ince et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S)	University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S)	Mirac Nedim Ince (Iowa City, Iowa); David E. Elliott (North Liberty, Iowa); George J. Weiner (Iowa City, Iowa)
ABSTRACT	The invention relates to helminthic parasite preparations and their use for treatment or prevention of GVHD in a subject that has undergone a transplant. The invention also related to helminthic parasite preparations and their use for prevention of GVHD in a subject prior to a transplant.
FILED	Friday, April 10, 2015
APPL NO	14/683778
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/001 (20130101) A61K 39/0003 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/577 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/6863 (20130101) G01N 33/6866 (20130101) G01N 33/56972 (20130101) G01N 2333/57 (20130101) G01N 2333/525 (20130101) G01N 2800/52 (20130101) G01N 2800/245 (20130101)
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09730993 — Engineered anthrax lethal toxin for targeted delivery

US 09730993	Leysath et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Clinton Edward Leysath (College Station, Texas); Stephen H Leppla (Rockville, Maryland); Damilola Daniel Phillips (Rockville, Maryland)
ABSTRACT	The present invention provides methods and systems for targeted delivery of a compound to a target cell that over-expresses two different proteinases. Specifically, two different modified protective antigen proteins, each comprising a cleavage site recognized by a distinct proteinase in place of the native proteinase cleavage site recognized by furin, are administered in combination with a compound that contains a protective antigen binding site. Upon cleavage by the two proteinases the two modified protective antigen proteins form a hetero-oligomer, allowing the compound to bind to the hetero-oligomer and subsequently to be translocated into the target cell.
FILED	Thursday, August 22, 2013
APPL NO	14/423408
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/07 (20130101) Original (OR) Class A61K 39/104 (20130101) A61K 47/48346 (20130101) Peptides C07K 14/32 (20130101)
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09730996 — Involucrin-driven retroviral expression cassettes encoding human immunodeficiency virus envelope glycoproteins

US 09730996	Gauduin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Texas Biomedical Research Institute (San Antonio, Texas)
ASSIGNEE(S)	Texas Biomedical Research Institute (San Antonio, Texas)
INVENTOR(S)	Marie-Claire Gauduin (Helotes, Texas); Philippe Blancou (Riaille, France)
ABSTRACT	The present invention provides for novel compositions and methods for delivering genes of interest to stem cells using vectors that contain differentiation-specific transcriptional regulatory elements. For example, stem cells in the internal epithelia could be transfected with a vaccine construct, which has an epithelial cell differentiation-specific promoter driving the expression of viral envelope proteins. When the promoter used is specific for terminally differentiated epithelial cells, then the viral envelope proteins will be expressed only in the upper part of the epithelia and therefore, stimulate the immune response. The infected epithelial stem cells in the basal layer will continue to produce new antigen-expressing cells, without being eliminated by the immune response. This invention will be useful in the development of vaccines against viral agents that target the internal mucosa like HIV.
FILED	Thursday, October 24, 2013
APPL NO	14/062125
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/523 (20130101) A61K 2039/5256 (20130101) A61K 2039/55566 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/86 (20130101) C12N 2740/15034 (20130101) C12N 2740/15041 (20130101)
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09731012 — Laser-actuated therapeutic nanoparticles

US 09731012	Arany et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Praveen Arany (Cambridge, Massachusetts); David J. Mooney (Sudbury, Massachusetts)
ABSTRACT	The invention provides compositions and methods for laser actuated drug delivery. Compositions comprise serum albumin based particles conjugated with therapeutic agents which cab become bioavailable upon actuation of the particles by light, e.g. low power laser.
FILED	Tuesday, March 12, 2013
APPL NO	14/389136
ART UNIT	1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1841 (20130101) A61K 41/0042 (20130101) Original (OR) Class A61K 47/48284 (20130101) A61K 47/48884 (20130101)
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09731014 — Use of SLURP1 as an imunomodulatory molecule in the ocular surface

US 09731014	Swamynathan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Shivalingappa Kottur Swamynathan (Glenshaw, Pennsylvania); Sudha Swamynathan (Glenshaw, Pennsylvania); Kristine-Ann Gallegos Buela (Pittsburgh, Pennsylvania); Robert Lee Hendricks (Pittsburgh, Pennsylvania)
ABSTRACT	Methods for treating inflammation are disclosed, such as for treating ocular inflammation. In some embodiments, the ocular inflammation is inflammation of an ocular surface, such as keratitis. The methods include administering to a subject with inflammation a therapeutically effective amount of SLURP1, or a nucleic acid encoding SLURP1, thereby treating the inflammation.
FILED	Friday, August 07, 2015
APPL NO	14/821567
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) A61K 38/177 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 2300/00 (20130101)
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09731032 — Aptamers for tumor initiating cells

US 09731032	Rich et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
ASSIGNEE(S)	The Cleveland Clinic Foundation (Cleveland, Ohio)
INVENTOR(S)	Jeremy N. Rich (Cleveland, Ohio); Youngmi Kim (Cleveland, Ohio); Anita B. Hjelmeland (Cleveland, Ohio)
ABSTRACT	Aptamers consisting of a single stranded nucleic acids having 100 nucleotides or less that specifically binds to tumor initiating cancer cells are described. The aptamers can be identified by screening a large pool of randomly generated aptamers to obtain a discrete set of aptamers that specifically bind to tumor initiating cancer cells, such as those found in brain cancer or glioblastoma. The aptamers can also be linked or complexed with anticancer agents or imaging agents for use in therapy or diagnosis.
FILED	Tuesday, February 04, 2014
APPL NO	14/763283
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/10 (20130101) A61K 47/48092 (20130101) A61K 47/48907 (20130101) Original (OR) Class A61K 47/48915 (20130101) A61K 49/0002 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/3517 (20130101) C12N 2320/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101)
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09731045 — Shape memory polymer

US 09731045	Gall et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	The Regents of the University of Colorado, a Body Corporate (Denver, Colorado)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
INVENTOR(S)	Kenneth Gall (Atlanta, Georgia); Christopher Yakacki (Denver, Colorado)
ABSTRACT	A polymer is composed of a linear chain acrylate and a multi-functional acrylate cross-linker. The polymerized composition exhibits a transition at a temperature between about 34° C. and about 50° C. The polymerized composition exhibits shape memory effects. In one embodiment, the linear chain is tert-butyl acrylate and the crosslinker is polyethylene glycol dimethacrylate. The resultant shape memory polymers may be used in medical devices to provide devices with different shapes for pre and post implantation.
FILED	Monday, January 06, 2014
APPL NO	14/148617
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/0401 (20130101) A61B 2017/0448 (20130101) A61B 2017/00871 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0811 (20130101) A61F 2002/0835 (20130101) A61F 2002/0858 (20130101) A61F 2002/0864 (20130101) A61F 2002/0882 (20130101) A61F 2002/0888 (20130101) A61F 2210/0014 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) Original (OR) Class A61L 27/50 (20130101) A61L 2400/16 (20130101) A61L 2430/02 (20130101)
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09731052 — Methods for stepwise deposition of silk fibroin coatings

US 09731052	Kaplan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Xianyan Wang (Acton, Massachusetts)
ABSTRACT	The invention provides a method for the controlled assembly of layered silk fibroin coatings using aqueous silk fibroin material. The methods described herein can be used to coat substrates of any material, shape, or size. Importantly, the described methods enable control of the biomaterial surface chemistry, thickness, morphology and structure using layered thin film coatings, or bulk coatings. Furthermore, the methods can be performed in all water and do not require intensive chemical processing enabling controlled entrapment of labile molecules such as, drugs, cytokines, and even cells or viruses to generate functional coatings that can be used in a variety of applications.
FILED	Wednesday, May 06, 2015
APPL NO	14/705509
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/32 (20130101) A61L 15/44 (20130101) A61L 27/50 (20130101) A61L 27/3604 (20130101) A61L 31/10 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 2300/43 (20130101) A61L 2300/416 (20130101) A61L 2400/12 (20130101) A61L 2400/18 (20130101)
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09732037 — 2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors

US 09732037	Silverman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Richard B. Silverman (Winnetka, Illinois); Qing Jing (Morton Grove, Illinois)
ABSTRACT	Aminopyridine compounds, as can be used in conjunction with methods for modulation of nitric oxide synthase activity.
FILED	Monday, August 15, 2016
APPL NO	15/237073
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 213/73 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 401/14 (20130101)
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09732067 — Compounds and methods for activating the apoptotic arm of the unfolded protein response

US 09732067	Golden et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	University of Kansas (Lawrence, Kansas); The Regents of the University of Michigan (Ann Arbor, Michigan); Wayne State University (Detroit, Michigan); Sanford-Burnham Medical Research Institute (La Jolla, California)
ASSIGNEE(S)	University of Kansas (Lawrence, Kansas); Sanford-Burnham Medical Research Institute (La Jolla, California); The Regents of the University of Michigan (Ann Arbor, Michigan); Wayne State University (Detroit, Michigan)
INVENTOR(S)	Jennifer E. Golden (Olathe, Kansas); Jeffrey Aube (Lawrence, Kansas); Daniel P. Flaherty (Overland Park, Kansas); Andrew M. Fribley (Brighton, Michigan); Randal J. Kaufman (San Diego, California); Thomas D. Y. Chung (Carlsbad, California); Anthony B. Pinkerton (San Diego, California); Michael Pablo Hedrick (Carlsbad, California)
ABSTRACT	N-substituted sulfonylphenyl-5-mitrofuranyl-2-carboxamide derived compounds, which selectively activate the apoptotic, but not the adaptive arm, of the Unfolded Protein Response are provided as is their use in the treatment of diseases such as diabetes, Alzheimer's, Parkinson's, hemophilia, lysosomal storage diseases and cancer.
FILED	Tuesday, June 18, 2013
APPL NO	14/408736
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/4525 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 303/36 (20130101) Heterocyclic Compounds C07D 307/71 (20130101) C07D 405/12 (20130101) Original (OR) Class
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09732083 — Tricyclic gyrase inhibitors

US 09732083	Bensen et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Daniel Bensen (Carlsbad, California); Zhiyong Chen (San Diego, California); John Finn (Encinitas, California); Thanh To Lam (San Diego, California); Suk Joong Lee (San Diego, California); Xiaoming Li (San Diego, California); Douglas W. Phillipson (Del Mar, California); Leslie William Tari (San Diego, California); Michael Trzoss (San Diego, California); Junhu Zhang (San Diego, California); Felice C. Lightstone (Fremont, California); Toan B. Nguyen (San Ramon, California); Sergio E. Wong (San Jose, California); Paul Aristoff (Dexter, Michigan); Michael Jung (Los Angeles, California)
ASSIGNEE(S)	MERCK SHARP and DOHME CORP. (New York, New York); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S)	Daniel Bensen (Carlsbad, California); Zhiyong Chen (San Diego, California); John Finn (Encinitas, California); Thanh To Lam (San Diego, California); Suk Joong Lee (San Diego, California); Xiaoming Li (San Diego, California); Douglas W. Phillipson (Del Mar, California); Leslie William Tari (San Diego, California); Michael Trzoss (San Diego, California); Junhu Zhang (San Diego, California); Felice C. Lightstone (Fremont, California); Toan B. Nguyen (San Ramon, California); Sergio E. Wong (San Jose, California); Paul Aristoff (Dexter, Michigan); Michael Jung (Los Angeles, California)
ABSTRACT	Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
FILED	Wednesday, March 14, 2012
APPL NO	13/496188
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 487/14 (20130101)
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09732101 — Bioreversible boronates for delivery of molecules into cells

US 09732101	Raines et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Ronald T. Raines (Madison, Wisconsin); Thomas P. Smith (Madison, Wisconsin)
ABSTRACT	Methods for enhancing cellular uptake of cargo molecules by boronating the cargo molecule, particularly with one or more phenylboronic acid groups. Boronation reagents for reversible boronation of cargo molecules, particularly, cargo molecules having one or more amino groups are provided.
FILED	Monday, July 27, 2015
APPL NO	14/809288
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48061 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class Peptides C07K 2319/43 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 11/00 (20130101) Enzymes C12Y 301/27005 (20130101)
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09732105 — Targeted nitroxide agents

US 09732105	Wipf et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Peter Wipf (Pittsburgh, Pennsylvania); Marie-Celine Frantz (Seine Saint Denis, France)
ABSTRACT	A compound having a structure of:
FILED	Friday, November 13, 2015
APPL NO	14/941466
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 209/46 (20130101) C07D 211/94 (20130101) C07D 295/24 (20130101) C07D 451/14 (20130101) C07D 453/02 (20130101) C07D 471/08 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) C07F 9/598 (20130101) Original (OR) Class
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09732121 — Rational vaccine design for hepatitis C virus

US 09732121	Foung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Thomas R. Fuerst (Damestown, Maryland)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Steven Foung (Stanford, California); Zhen-Yong Keck (Redwood City, California); Thomas R. Fuerst (Damestown, Maryland)
ABSTRACT	Compositions and methods are provided relating to HCV E2 protein and modifications thereto which enhance the immunogenicity of the protein for vaccine development with respect to the generation of a neutralizing immune response.
FILED	Monday, September 22, 2014
APPL NO	14/493153
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/57 (20130101) A61K 2039/55572 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24222 (20130101) C12N 2770/24234 (20130101)
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09732127 — Colorimetric and fluorescent proteins

US 09732127	Borhan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Babak Borhan (Okemos, Michigan); James Geiger (Webberville, Michigan); Wenjing Wang (Cambridge, Massachusetts); Chrysoula Vasileiou (East Lansing, Michigan); Kin Sing Lee (Davis, California); Tetyana Berbasova (East Lansing, Michigan)
ABSTRACT	The invention relates to intracellular lipid binding proteins that bind retinoids and/or dye ligands and that are modified to transmit or emit light at a variety of different wavelengths.
FILED	Thursday, October 15, 2015
APPL NO	14/883944
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 14/47 (20130101) Original (OR) Class C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101)
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09732132 — Therapeutic compositions and methods for disorders associated with neuronal degeneration

US 09732132	Rex et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Tonia S. Rex (Goodlettsville, Tennessee); Timothy A. Sullivan (Savannah, Georgia)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Tonia S. Rex (Goodlettsville, Tennessee); Timothy A. Sullivan (Savannah, Georgia)
ABSTRACT	Disclosed are isolated mutant erythropoietin (EPO) polypeptides, functional fragment thereof, nucleic acid encoding such peptides, vectors including such nucleic acids and compositions including such peptides and nucleic acids. The mutant EPO peptides are unique in that they include a substitution at amino acid position number 76, such as a glutamic acid for arginine substitution at position 76. This substitution inhibits erythropoietic activity while retaining their neuroprotection. Also disclosed are methods of treating or inhibiting neuronal degeneration, reducing or inhibiting one or more symptoms associated with neuronal degeneration and/or glaucoma in a subject. The methods include administering a therapeutically effective amount of a isolated mutant erythropoietin EPO polypeptide, an expression vector encoding such a mutant erythropoietin EPO polypeptide, a viral particle including an expression vector, or a composition, thereby treating or inhibiting neuronal degeneration in the subject.
FILED	Friday, January 13, 2012
APPL NO	13/979451
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/505 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) C12N 7/00 (20130101) C12N 15/00 (20130101) C12N 15/10 (20130101) C12N 15/86 (20130101)
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09732146 — Antibody-mediated transduction of heat shock proteins into living cells

US 09732146	Nishimura et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Robert N. Nishimura (Sepulveda, California); Richard H. Weisbart (Sepulveda, California); James Hansen (Guilford, Connecticut)
ASSIGNEE(S)	The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Robert N. Nishimura (Sepulveda, California); Richard H. Weisbart (Sepulveda, California); James Hansen (Guilford, Connecticut)
ABSTRACT	The invention provides for a fusion protein comprising a 3E10 Fv joined to a Hsp-70, Hsp-27, Hsp-90 or GRP-78 or portion thereof, and optionally, the 3E10 Fv comprising an amino acid sequence AGIH at its amino terminus.
FILED	Friday, March 15, 2013
APPL NO	13/815829
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/48538 (20130101) Peptides C07K 14/47 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/56 (20130101) C07K 2317/77 (20130101) C07K 2317/622 (20130101) C07K 2319/33 (20130101)
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09732317 — Highly efficient gas permeable devices and methods for culturing cells

US 09732317	Wilson
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Wilson Wolf Manufacturing Corporation (New Brighton, Minnesota)
ASSIGNEE(S)	Wilson Wolf Manufacturing Corporation (New Brighton, Minnesota)
INVENTOR(S)	John R. Wilson (New Brighton, Minnesota)
ABSTRACT	This invention relates to methods and devices that improve cell culture efficiency. They include the use of gas permeable culture compartments that reduce the use of space while maintaining uniform culture conditions, and are more suitable for automated liquid handling. They include the integration of gas permeable materials into the traditional multiple shelf format to resolve the problem of non-uniform culture conditions. They include culture devices that use surfaces comprised of gas permeable, plasma charged silicone and can integrate traditional attachment surfaces, such as those comprised of traditional tissue culture treated polystyrene. They include culture devices that integrate gas permeable, liquid permeable membranes. A variety of benefits accrue, including more optimal culture conditions during scale up and more efficient use of inventory space, incubator space, and disposal space. Furthermore, labor and contamination risk are reduced.
FILED	Wednesday, July 02, 2014
APPL NO	14/321933
ART UNIT	1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 23/08 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) Original (OR) Class
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09732320 — Selective differentiation, identification, and modulation of human TH17 cells

US 09732320	Kuchroo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Vijay K. Kuchroo (Newton, Massachusetts); David E. Anderson (Boston, Massachusetts); Estelle Bettelli (Newcastle, Washington); David Hafler (Newton, Massachusetts); Mohammed Oukka (Newcastle, Washington)
ABSTRACT	The embodiments provide for the modulation of both the differentiation and activity of human TH17 cells. More specifically, human TH17 cell differentiation can modulated by TGF-β and IL-21, and their agonists and antagonists. Function of TH17 cells can be modulated by, for example, BLT1 or podoplanin, and their agonists and antagonists. Additionally, the embodiments provide for the identification of TH17 cells. More specifically, human TH17 cells specifically upregulate BLT1 and podoplanin.
FILED	Friday, October 17, 2014
APPL NO	14/517116
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class
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09732322 — Compositions for mesoderm derived ISL1+ multipotent cells (IMPs), epicardial progenitor cells (EPCs) and multipotent C56C cells (C56Cs) and methods of producing and using same

US 09732322	Dalton et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S)	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
INVENTOR(S)	Stephen Dalton (Athens, Georgia); David Reynolds (Kilsyth, Australia)
ABSTRACT	The present invention relates to inter alia, methods for the generation and maintenance of Mesoderm-derived ISL1+ Multipotent Progenitors (IMPs), the production of a number of pluripotent cells including and epicardial pluripotent cells (EPCs) and using these cells to produce endothelial cells, cardiomyocytes, smooth muscle cells, vascular cells and other cells and related methods as otherwise disclosed herein. The invention also relates to compositions comprising a population of cells.
FILED	Thursday, December 10, 2015
APPL NO	14/965222
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 5/0606 (20130101) C12N 5/0656 (20130101) C12N 5/0657 (20130101) Original (OR) Class C12N 5/0661 (20130101) C12N 5/0662 (20130101) C12N 5/0692 (20130101) C12N 2501/11 (20130101) C12N 2501/16 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/165 (20130101) C12N 2501/195 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2502/13 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2533/78 (20130101) C12N 2533/90 (20130101)
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09732337 — RNA nanoparticles and nanotubes

US 09732337	Shapiro et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Bruce A. Shapiro (Gaithersburg, Maryland); Yaroslava G. Yingling (Cary, North Carolina); Eckart Bindewald (Frederick, Maryland); Wojciech Kasprzak (Frederick, Maryland); Luc Jaeger (Goleta, California); Isil Severcan (Niskayuna, New York); Cody Geary (Santa Barbara, California); Kirill Afonin (Frederick, Maryland)
ASSIGNEE(S)	The United Stated of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Bruce A. Shapiro (Gaithersburg, Maryland); Yaroslava G. Yingling (Cary, North Carolina); Eckart Bindewald (Frederick, Maryland); Wojciech Kasprzak (Frederick, Maryland); Luc Jaeger (Goleta, California); Isil Severcan (Niskayuna, New York); Cody Geary (Santa Barbara, California); Kirill Afonin (Frederick, Maryland)
ABSTRACT	The instant invention provides polyvalent RNA nanoparticles comprising RNA motifs as building blocks that can form RNA nanotubes. The polyvalent RNA nanoparticles are suitable for therapeutic or diagnostic use in a number of diseases or disorders.
FILED	Wednesday, June 16, 2010
APPL NO	13/378935
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48092 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 2310/51 (20130101)
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09732349 — In vivo unnatural amino acid expression in the methylotrophic yeast Pichia pastoris

US 09732349	Young et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Travis Young (San Diego, California); Peter G. Schultz (La Jolla, California)
ABSTRACT	The invention provides orthogonal translation systems for the production of polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris. Methods for producing polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris are also provided.
FILED	Monday, January 27, 2014
APPL NO	14/165199
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48384 (20130101) Peptides C07K 2319/00 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/815 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101)
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09732358 — PIV5 as oncolytic agent

US 09732358	He
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S)	Biao He (Bogart, Georgia)
ABSTRACT	The present invention includes the Paramyxovirus Parainfluenza Virus 5 (PIV5) as an oncolytic agent for treating various cancers, including, but not limited to breast cancer, lung cancer and melanoma. PIV5 oncolytic agents include both wild type PIV5 and various recombinant PIV5 constructs. Recombinant PIV5 constructs may include PIV5 lacking the conserved C-terminus of the V protein (PIV5VAC), PIV5 with mutations in the N-terminus of the V/P protein (PIV5CPI−), and PIV5 expressing MDA-7/IL-24 (rPIV5-MDA7), rPIV5-V/P-CPI−, rPIV5-CPI+, rPIV-Rev, rPIV5-RL, rPIV5-P-S157A, rPIV5-P-S308A, rPIV5-L-A1981D, rPIV5-F-S443P, rPIV5-MDA7, rPIV5ASH-CPI−, or rPIV5ASH-Rev. Also included are methods of making and using such oncolytic agents and compositions including such oncolytic agents.
FILED	Thursday, January 24, 2013
APPL NO	14/374070
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/04 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/155 (20130101) A61K 39/205 (20130101) A61K 2039/53 (20130101) A61K 2039/552 (20130101) A61K 2039/585 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2760/16134 (20130101) C12N 2760/16171 (20130101) C12N 2760/18021 (20130101) C12N 2760/18034 (20130101) C12N 2760/18721 (20130101) C12N 2760/18732 (20130101) C12N 2760/18743 (20130101) C12N 2760/18771 (20130101) C12N 2760/20134 (20130101) C12N 2760/20171 (20130101)
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09732359 — Replication-competent adenoviral vectors

US 09732359	Peng et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Istituto Superiore di Sanitá (Rome, Italy)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland); Istituto Superiore di Sanita (Rome, Italy)
INVENTOR(S)	Bo Peng (Rockville, Maryland); Rebecca Voltan (Ferrara, Italy); Barbara Ensoli (Rome, Italy); Marjorie Robert-Guroff (Rockville, Maryland)
ABSTRACT	This invention provides improved replication-competent adenoviral vectors. The improved vectors have both a hybrid regulatory unit that provides for high level transgene expression. The vectors can be use, e.g., for therapeutic or prophylactic purposes.
FILED	Tuesday, December 08, 2015
APPL NO	14/963172
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 2039/575 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/16143 (20130101) C12N 2740/15034 (20130101) C12N 2740/15071 (20130101) C12N 2740/16034 (20130101) C12N 2740/16071 (20130101) C12N 2740/16134 (20130101) C12N 2740/16234 (20130101) C12N 2740/16334 (20130101)
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09732379 — Encoded nanopore sensor for multiplex nucleic acids detection

US 09732379	Gu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S)	The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Li-Qun Gu (Columbia, Missouri); Xinyue Zhang (Columbia, Missouri)
ABSTRACT	The present invention provides a new and improved multiplexed oligonucleotide detection method based on the nanopore technology with one or more probes containing a sequence with complementarity to the target oligonucleotide, a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini and a label attached to the terminus. The improved probes and probe sets enable sensitive, selective, and direct multiplex detection, differentiation and quantification of distinct target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method based on miRNA levels in the patient's tissue sample.
FILED	Friday, March 14, 2014
APPL NO	14/213140
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6825 (20130101) C12Q 1/6876 (20130101) C12Q 2537/143 (20130101) C12Q 2545/114 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101)
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09732381 — Method for sequencing a heteropolymeric target nucleic acid sequence

US 09732381	Stoddart et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S)	David Stoddart (Oxford, United Kingdom); Andrew John Heron (Oxford, United Kingdom); Giovanni Maglia (Kessel-Lo, Belgium); John Hagan Pryce Bayley (Oxford, United Kingdom)
ASSIGNEE(S)	OXFORD UNIVERSITY INNOVATION LIMITED (Oxford, United Kingdom)
INVENTOR(S)	David Stoddart (Oxford, United Kingdom); Andrew John Heron (Oxford, United Kingdom); Giovanni Maglia (Kessel-Lo, Belgium); John Hagan Pryce Bayley (Oxford, United Kingdom)
ABSTRACT	The invention relates to a method for sequencing a heteropolymeric target nucleic acid sequence that involves stochastic sensing. The invention also relates to a method for improving a pore for sequencing a target nucleic acid sequence by modifying one or more sites in the pore.
FILED	Thursday, March 25, 2010
APPL NO	13/260178
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2521/101 (20130101) C12Q 2521/319 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101)
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09732386 — Cell aging as a unique biomarker of major depression

US 09732386	Wolkowitz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	Owen M. Wolkowitz (Palo Alto, California); Synthia H. Mellon (San Francisco, California); Elissa S. Epel (San Francisco, California); Jue Lin (Foster City, California); Elizabeth H. Blackburn (San Francisco, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Owen M. Wolkowitz (Palo Alto, California); Synthia H. Mellon (San Francisco, California); Elissa S. Epel (San Francisco, California); Jue Lin (Foster City, California); Elizabeth H. Blackburn (San Francisco, California)
ABSTRACT	The present invention provides methods of determining whether a subject is a suitable candidate for an anti-depressant treatment to alleviate a mood disorder by measuring telomere length and telomerase activity. The present invention also provides methods of assessing the efficacy of an anti-depressant treatment to alleviate a mood disorder and of predicting whether a subject is at risk of developing depression.
FILED	Friday, June 24, 2011
APPL NO	13/703881
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101)
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09732387 — Biomarker associated with irritable bowel syndrome and Crohn's disease

US 09732387	Merchant et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Juanita L. Merchant (Ann Arbor, Michigan); Helmut Grasberger (Ann Arbor, Michigan)
ABSTRACT	The present invention provides compositions and methods for characterizing irritable bowel syndrome. In particular, the present invention provides compositions and methods for determining polymorphisms associated with IBS-D and Crohn's disease. The present invention further provides compositions and methods for determining a treatment course of action in subjects with IBS-D and Crohn's disease.
FILED	Wednesday, April 03, 2013
APPL NO	14/389961
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) Electric Digital Data Processing G06F 19/3431 (20130101) G06F 19/3456 (20130101)
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09732389 — Methods and compositions for correlating genetic markers with prostate cancer risk

US 09732389	Xu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Jianfeng Xu (Clemmons, North Carolina); Siqun Lilly Zheng (Clemmons, North Carolina); Jielin Sun (Oak Ridge, North Carolina); Andrew Karim Kader (San Diego, California)
ASSIGNEE(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S)	Jianfeng Xu (Clemmons, North Carolina); Siqun Lilly Zheng (Clemmons, North Carolina); Jielin Sun (Oak Ridge, North Carolina); Andrew Karim Kader (San Diego, California)
ABSTRACT	The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and determining a genotype for the subject at a plurality of biallelic polymorphic loci, wherein each of said plurality has an associated allele and an unassociated allele, wherein the genotype is selected from the group consisting of homozygous for the associated allele, heterozygous, and homozygous for the unassociated allele; and b) calculating a cumulative relative risk (CRR) for the subject based on the genotype determined in step (a). A CRR of greater than 1.00 identifies a subject as having an increased risk of developing prostate cancer and also can identify a subject who is a candidate for early PSA screening, prostate biopsy and/or chemoprevention.
FILED	Friday, September 02, 2011
APPL NO	13/818602
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/172 (20130101)
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09733125 — Resonator enhanced raman spectroscopy

US 09733125	Liu et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC) National Institute for Occupational Safety and Health (NIOSH) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania); Washington University (St. Louis, Missouri)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania); Washington University (St. Louis, Missouri)
INVENTOR(S)	Zhiwen Liu (State College, Pennsylvania); Lan Yang (Saint Louis, Missouri); Perry Edwards (State College, Pennsylvania); Corey Janisch (University Park, Pennsylvania); Bo Peng (Saint Louis, Missouri); Sahin Ozdemir (University City, Missouri)
ABSTRACT	Embodiments of the invention provide Raman spectroscopy methods and devices that exploit high quality factor (Q) resonators to enhance Raman signal by several orders of magnitude over the signal typically expected for Raman methods. Embodiments typically include one or more resonators, typically microtoroid microresonators. Embodiments also take advantage of Rayleigh scattering using these microresonators. Embodiments may be particularly useful for non-labeled nanoparticle sensing.
FILED	Wednesday, September 25, 2013
APPL NO	14/431080
ART UNIT	2877 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/26 (20130101) G01J 3/44 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 3/0224 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101)
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09733165 — Methods and apparatus for the isolation and enrichment of circulating tumor cells

US 09733165	Chiu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Daniel T. Chiu (Seattle, Washington); Jason S. Kuo (Seattle, Washington)
ABSTRACT	Embodiments in accordance with the present invention relate to methods and apparatuses for concentrating and isolating Circulating Tumor Cells (CTCs) from body fluids. One embodiment of the present invention includes a micro-fabricated or nano-fabricated device having channels configured for separating and excluding. Embodiments in accordance with the present invention utilize features that reduce the hydrodynamic pressure experienced by the cells during the separation, isolation and concentration processes, and therefore reduce the likelihood of cell lysis or other damage to the cells.
FILED	Friday, January 31, 2014
APPL NO	14/170381
ART UNIT	1677 — Printing/Measuring and Testing
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 3/502753 (20130101) B01L 2200/0668 (20130101) B01L 2300/0681 (20130101) B01L 2400/0409 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class
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09733237 — Methods for identifying candidates for the treatment of neurodegenerative diseases

US 09733237	Wichterle et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Hynek Wichterle (New York, New York); Christopher E Henderson (New York, Japan); Sebastian Thams (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Hynek Wichterle (New York, New York); Christopher E Henderson (New York, Japan); Sebastian Thams (New York, New York)
ABSTRACT	The present invention provides, inter alia, methods for identifying a candidate agent that may be effective to treat or ameliorate an effect of a neurodegenerative disease in a subject. These methods include: (a) contacting a wildtype neuron and a mutant neuron with a stressor which is effective to accelerate the degeneration of the mutant neuron; (b) further contacting the wildtype neuron and the mutant neuron from step (a) with a candidate agent; and (c) determining whether the candidate agent lowers a wildtype to mutant survival ratio or increases both wildtype and mutant neuron survival.
FILED	Thursday, October 31, 2013
APPL NO	14/439620
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/407 (20130101) A61K 31/519 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/5058 (20130101) Original (OR) Class G01N 2333/914 (20130101) G01N 2500/00 (20130101) G01N 2500/10 (20130101) G01N 2800/28 (20130101) G01N 2800/2835 (20130101)
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09733247 — Detection of an immune response

US 09733247	Kwok et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Benaroya Research Institute (Seattle, Washington)
ASSIGNEE(S)	Benaroya Research Institute (Seattle, Washington)
INVENTOR(S)	William W. Kwok (Bellevue, Washington); Erik Wambre (Seattle, Washington)
ABSTRACT	Provided herein are methods of detecting and/or monitoring the presence or severity of an immune disorder in a subject, including detecting a frequency of a Th2a subset of CD4+ T cells in a biological sample of the subject. In some embodiments, the detecting includes: (a) detecting a frequency of CD4+ T cells in a biological sample of said subject; (b) detecting a frequency of a Th2a subset of the CD4+ T cells in the biological sample; and (c) comparing the frequency of the Th2a subset with the frequency of the CD4+ T cells.
FILED	Thursday, January 07, 2016
APPL NO	14/990126
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/35 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/56972 (20130101) G01N 33/56977 (20130101) Original (OR) Class G01N 2333/726 (20130101) G01N 2333/70514 (20130101) G01N 2333/70596 (20130101) G01N 2800/24 (20130101)
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09733250 — Device for capturing circulating cells

US 09733250	Tseng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Hsian-Rong Tseng (Los Angeles, California); Shutao Wang (Los Angeles, California); Hao Wang (Los Angeles, California); Kan Liu (Los Angeles, California)
ABSTRACT	The present invention provides devices and methods for capturing rare cells. The devices and methods described herein can be used to facilitate the diagnosis and monitoring of metastatic cancers.
FILED	Monday, August 24, 2015
APPL NO	14/834024
ART UNIT	1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502761 (20130101) B01L 2200/0668 (20130101) B01L 2300/0636 (20130101) B01L 2300/0816 (20130101) B01L 2300/0877 (20130101) B01L 2300/0887 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54366 (20130101) G01N 33/57492 (20130101) Original (OR) Class
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09733258 — Biomarker for determining mitochondrial damage in friedreich's ataxia

US 09733258	Payne et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S)	R. Mark Payne (Zionsville, Indiana); Gregory R. Wagner (Indianapolis, Indiana); Clifford M. Babbey (Indianapolis, Indiana); P. Melanie Pride (Indianapolis, Indiana)
ABSTRACT	Compositions and methods for screening for a disease or a disorder associated with a deficiency in frataxin in a subject using biomarkers for diseases or disorders associated with a deficiency in frataxin are disclosed. The compositions and methods include determining the acetylation status of mitochondrial proteins. Also disclosed are methods of detecting progression of a disease or a disorder associated with a deficiency in frataxin in a subject and methods of monitoring effectiveness of a therapy for diseases or disorders associated with a deficiency in frataxin.
FILED	Friday, March 01, 2013
APPL NO	14/382367
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48 (20130101) G01N 33/50 (20130101) G01N 33/68 (20130101) G01N 33/5079 (20130101) G01N 33/5735 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2440/10 (20130101) G01N 2500/02 (20130101) G01N 2800/52 (20130101) G01N 2800/285 (20130101)
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09733326 — Selective zero-quantum coherence transfer (Sel-ZQC) method for metabolite imaging in a poorly shimmed magnet field without susceptibility artifact

US 09733326	He
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Qiuhong He (Wexford, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Qiuhong He (Wexford, Pennsylvania)
ABSTRACT	Systems and methods employing spin editing techniques to improve magnetic resonance spectroscopy (MRS) and magnetic resonance spectroscopic imaging (MRSI) are discussed. Using these spin editing techniques, magnetic resonance signals of one or more non-target chemicals (chemicals whose signals are to be filtered out or suppressed) chemicals can be suppressed, so that the signal(s) of a set of target chemicals can be obtained without signals from the one or more non-target chemicals. Information about and differences between the molecular topologies of the first set of chemicals and the one or more unwanted chemicals can be used to design a sequence that suppresses the one or more unwanted chemicals while allowing acquisition of signal(s) from the first set of chemicals. These techniques can be employed to recover sharp peaks despite magnetic field inhomogeneities and susceptibility effects.
FILED	Monday, April 09, 2012
APPL NO	14/004624
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/4312 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/341 (20130101) G01R 33/485 (20130101) Original (OR) Class G01R 33/3415 (20130101) G01R 33/3635 (20130101) G01R 33/4608 (20130101) G01R 33/4633 (20130101) G01R 33/34046 (20130101) G01R 33/56536 (20130101)
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09733465 — Waveguides for enhanced total internal reflection fluorescence microscopy

US 09733465	Mickolajczyk et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Keith Mickolajczyk (University Park, Pennsylvania); Yixin Yan (University Park, Pennsylvania); Yiyang Gong (University Park, Pennsylvania); Haoyu Li (University Park, Pennsylvania); Noel Christopher Giebink (University Park, Pennsylvania); Thomas Jackson (University Park, Pennsylvania); William Hancock (University Park, Pennsylvania)
ABSTRACT	Evanescently-coupled planar waveguides for enhancing total internal reflection fluorescence microscopy are disclosed. The waveguides include multiple thin layers of one or more materials on a cover slip arranged resonantly enhance the optical field at the surface of the layer stack by evanescently coupling to a leaky guided mode.
FILED	Thursday, February 11, 2016
APPL NO	15/041384
ART UNIT	2874 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/648 (20130101) G01N 21/6458 (20130101) G01N 2021/6482 (20130101) Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) G02B 6/2726 (20130101) G02B 6/29331 (20130101) G02B 21/16 (20130101) G02B 21/34 (20130101) Original (OR) Class
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09734122 — System, method and computer-accessible medium for evaluating a malignancy status in at-risk populations and during patient treatment management

US 09734122	Vuskovic et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Marko I. Vuskovic (Bonsall, California); Margaret E. Huflejt (La Jolla, California); Harvey I. Pass (Bronxville, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	Marko I. Vuskovic (Bonsall, California); Margaret E. Huflejt (La Jolla, California); Harvey I. Pass (Bronxville, New York)
ABSTRACT	In accordance with certain exemplary embodiments of the present disclosure, exemplary visualization system, method, procedure and computer-accessible medium can be provided, which individually and/or collectively can be called, e.g., ImmunoRuler (IR). Certain exemplary embodiments of the exemplary IR in accordance with the present disclosure can be used for, e.g., comparing two groups of objects with specific and distinguished properties, such as a group of case subjects with a particular disease and a group of control subjects without that particular disease, and/or a group of subjects with a particular disease who are given a treatment and a group of subjects with the same disease but under another treatment or no treatment at all.
FILED	Friday, March 25, 2011
APPL NO	13/636432
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Electric Digital Data Processing G06F 15/00 (20130101) Original (OR) Class G06F 17/30595 (20130101) G06F 19/24 (20130101) G06F 19/26 (20130101)
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09734573 — Methods and systems for automatically determining magnetic field inversion time of a tissue species

US 09734573	Spottiswoode et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as respresented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia); Siemens Healthcare GmbH (Erlangen, Germany)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia); Siemens Healthcare GmbH (Erlangen, Germany)
INVENTOR(S)	Bruce S. Spottiswoode (Chicago, Illinois); Xiaoguang Lu (West Windsor, New Jersey); Xiaoming Bi (Aurora, Illinois); Hui Xue (Englewood, New Jersey); Christopher Glielmi (Hoboken, New Jersey); Peter Kellman (Bethesda, Maryland); Andreas Greiser (Erlangen, Germany)
ABSTRACT	A computer-implemented method for determining magnetic field inversion time of a tissue species includes generating a T1-mapping image of a tissue of interest, the T1-mapping image comprising a plurality of T1 values within an expected range of T1 values for the tissue of interest. An image mask is created based on predetermined identification information about the tissue of interest. Next, an updated image mask is created based on a largest connected region in the image mask. The updated image mask is applied to the T1-mapping image to yield a masked image. Then, a mean relaxation time value is determined for the largest connected region. The mean relaxation time value is then used to determine a time point for nulling longitudinal magnetization.
FILED	Friday, April 04, 2014
APPL NO	14/245011
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10088 (20130101) G06T 2207/30048 (20130101)
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Department of Defense (DOD)

09730783 — Ultra-low fractional area coverage flow diverter for treating aneurysms and vascular diseases

US 09730783	Carman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Gregory P. Carman (Los Angeles, California); Daniel S. Levi (Pacific Palisades, California); Youngjae Chun (Pittsburgh, Pennsylvania); Fernando Vinuela (Los Angeles, California)
ABSTRACT	A flow diverter is described and fabricated using ultra-thin porous thin-film Nitinol, and is configured for implantation to a treatment site within a vessel for significant reduction in an intra-aneurismal flow velocity and vorticity. Using small size pores in a coverage area of only 10%, a 90% reduction in flow velocity into a pseudo-aneurysm can be achieved, with an almost immediate cessation of flow into an anatomical feature such as aneurysm sac in vivo. The size of the holes can be tailored to be any shape and range in size from 1-400 μm using photolithography and from 5-1000 nm using ebeam lithography.
FILED	Saturday, November 03, 2012
APPL NO	13/668241
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/07 (20130101) Original (OR) Class A61F 2/90 (20130101) A61F 2002/068 (20130101) A61F 2002/075 (20130101) A61F 2002/077 (20130101) A61F 2002/823 (20130101) A61F 2230/0054 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/14 (20130101) A61L 31/022 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0005 (20130101) C23C 14/34 (20130101) C23C 14/185 (20130101) C23C 14/5806 (20130101) C23C 14/5873 (20130101)
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09730813 — Arm prosthetic device

US 09730813	Evans et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Research, Development and Engineering Command (RDECOM)
APPLICANT(S)	DEKA Products Limited Partnership (Manchester, New Hampshire)
ASSIGNEE(S)	DEKA Products Limited Partnership (Manchester, New Hampshire)
INVENTOR(S)	Christopher O. Evans (Amherst, New Hampshire); N. Christopher Perry (Manchester, New Hampshire); Dirk A. van der Merwe (Canterbury, New Hampshire); Keith D. Violette (Sandown, New Hampshire); Stewart M. Coulter (Bedford, New Hampshire); Thomas A. Doyon (Manchester, New Hampshire); David Blumberg, Jr. (Deerfield, New Hampshire)
ABSTRACT	A prosthetic limb including a plurality of segments that provide a user of the prosthetic limb with substantially the same movement capability and function as a human arm. The segments are connectable to one another and connectable to a prosthetic support apparatus. The prosthetic limb includes a controller and at least one antenna in connection with the controller for transmitting and receiving signals, the at least one antenna including a housing of a segment of the prosthetic limb as a radiating element. The prosthetic limb further including a user interface incorporated therein and one or more communication systems for communicating with external devices. The user interface is integrally formed in the housing and includes a status indicator for displaying information. A flexible protective cover is disposed around a portion of the housing and covers the user interface, the flexible protective cover includes a translucent portion over the status indicator.
FILED	Monday, March 16, 2015
APPL NO	14/658840
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) Original (OR) Class A61F 2/68 (20130101) A61F 2/78 (20130101) A61F 2/581 (20130101) A61F 2/582 (20130101) A61F 2/585 (20130101) A61F 2/586 (20130101) A61F 2002/587 (20130101) A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/705 (20130101) A61F 2002/747 (20130101) A61F 2002/764 (20130101) A61F 2002/769 (20130101) A61F 2002/5001 (20130101) A61F 2002/5061 (20130101) A61F 2002/5083 (20130101) A61F 2002/6836 (20130101) A61F 2002/6845 (20130101) A61F 2002/6881 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/7665 (20130101) A61F 2002/7862 (20130101) A61F 2002/30464 (20130101) A61F 2220/0075 (20130101) A61F 2250/008 (20130101) A61F 2250/0074 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 15/0009 (20130101) B25J 18/00 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 41/12 (20130101) F16D 41/105 (20130101)
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09731266 — Linear valve arrays

US 09731266	Stern et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	IntegenX Inc. (Pleasanton, California)
ASSIGNEE(S)	IntegenX Inc. (Pleasanton, California)
INVENTOR(S)	Seth Stern (Palo Alto, California); Stevan B. Jovanovich (Livermore, California)
ABSTRACT	The invention provides systems, devices, methods, and kits for performing an integrated analysis. The integrated analysis can include sample processing, library construction, amplification, and sequencing. The integrated analysis can be performed within one or more modules that are fluidically connected to each other. The one or more modules can be controlled and/or automated by a computer. The integrated analysis can be performed on a tissue sample, a clinical sample, or an environmental sample. The integrated analysis system can have a compact format and return results within a designated period of time.
FILED	Tuesday, July 21, 2015
APPL NO	14/804675
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00389 (20130101) B01J 2219/00599 (20130101) B01J 2219/00716 (20130101) B01J 2219/00722 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 7/52 (20130101) B01L 2200/10 (20130101) B01L 2200/16 (20130101) B01L 2200/0647 (20130101) B01L 2300/087 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2400/043 (20130101) B01L 2400/0481 (20130101) B01L 2400/0655 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 99/0015 (20130101) F16K 99/0059 (20130101) F16K 2099/0084 (20130101)
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09731284 — Process for oxidation of amines in the synthesis of energetic materials

US 09731284	Sanchez et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia); Seton Hall University (South Dramse, New Jersey)
INVENTOR(S)	Peggy A. Sanchez (Sparta, New Jersey); Kimberly Griswold (Flanders, New Jersey); Sergiu M. Gorun (Montclair, New Jersey); Hemantbhai H. Patel (Piscataway, New Jersey)
ABSTRACT	A process for use of composite catalysts for oxidation of amines during synthesis of energetic compounds. This method overcomes the safety concerns associated with dangerous reaction conditions for these energetic materials. The process requires exposing phthalocyanine conjugated to an inorganic substrate to the precursor reactant and activating the composite material to light and oxygen to covert amine groups into oxidized nitrogen species.
FILED	Wednesday, February 24, 2016
APPL NO	15/051884
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/38 (20130101) Original (OR) Class B01J 31/183 (20130101) B01J 2231/70 (20130101) B01J 2531/26 (20130101)
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09731293 — Paired laser and electrokinetic separation, manipulation, and analysis device

US 09731293	Terray et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Alexander V. Terray (Alexandria, Virginia); Sean J. Hart (Keswick, Virginia); Sarah J. R. Staton (Washington, District of Columbia); Gregory E. Collins (Huntingtown, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Alexander V. Terray (Alexandria, Virginia); Sean J. Hart (Keswick, Virginia); Sarah J. R. Staton (Washington, District of Columbia); Gregory E. Collins (Huntingtown, Maryland)
ABSTRACT	The combined value of integrating optical forces and electrokinetics allows for the pooled separation vectors of each to be applied, providing for separation based on combinations of features such as size, shape, refractive index, charge, charge distribution, charge mobility, permittivity, and deformability. The interplay of these separation vectors allow for the selective manipulation of analytes with a finer degree of variation. Embodiments include methods of method of separating particles in a microfluidic channel using a device comprising a microfluidic channel, a source of laser light focused by an optic into the microfluidic channel, and a source of electrical field operationally connected to the microfluidic channel via electrodes so that the laser light and the electrical field to act jointly on the particles in the microfluidic channel. Other devices and methods are disclosed.
FILED	Tuesday, October 01, 2013
APPL NO	14/043384
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0652 (20130101) B01L 2300/0864 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) B01L 2400/0424 (20130101) B01L 2400/0454 (20130101) B01L 2400/0487 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/1081 (20130101)
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09731297 — Assay cartridges and methods of using the same

US 09731297	Glezer et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Congressionally Directed Medical Research Programs (CDMRP) U.S. Army Medical Research and Materiel Command (USAMRMC) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	Eli N. Glezer (Del Mar, California); Stephen Higgins (Gaithersburg, Maryland); Sandor Kovacs (Middletown, Delaware); Sudeep Kumar (Gaithersburg, Maryland); Kenneth Page (Germantown, Maryland); Kristian Roth (Germantown, Maryland); George Sigal (Rockville, Maryland)
ASSIGNEE(S)	MESO SCALE TECHNOLOGIES, LLC. (Rockville, Maryland)
INVENTOR(S)	Eli N. Glezer (Del Mar, California); Stephen Higgins (Gaithersburg, Maryland); Sandor Kovacs (Middletown, Delaware); Sudeep Kumar (Gaithersburg, Maryland); Kenneth Page (Germantown, Maryland); Kristian Roth (Germantown, Maryland); George Sigal (Rockville, Maryland)
ABSTRACT	Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
FILED	Thursday, January 05, 2012
APPL NO	13/343834
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 7/525 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2200/146 (20130101) B01L 2200/0605 (20130101) B01L 2200/0621 (20130101) B01L 2200/0631 (20130101) B01L 2300/087 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) B01L 2400/0487 (20130101) B01L 2400/0688 (20130101) B01L 2400/0694 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101)
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09731471 — Curved high temperature alloy sandwich panel with a truss core and fabrication method

US 09731471	Schaedler et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) Department of the Army (DOA) Research, Development and Engineering Command (RDECOM)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Tobias A. Schaedler (Oak Park, California); Jacob M. Hundley (Los Angeles, California); John H. Martin (Ventura, California); Christopher S. Roper (Santa Monica, California); Eric C. Clough (Santa Monica, California)
ABSTRACT	A lightweight sandwich panel structure with a complex shape and curvature, and a method to fabricate such a panel out of high temperature alloys. Embodiments of a micro-truss core structure that offer high specific strength and stiffness while allowing for curvature, and methods for depositing multiple layers of metals that can be interdiffused into complex alloys, are provided. A core of a panel may be fabricated from a polymer template, which may be shaped, e.g., curved, and coated with metal layers, which may then be heat treated to cause the layers of metal to interdiffuse, to form an alloy.
FILED	Tuesday, December 15, 2015
APPL NO	14/970521
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0053 (20130101) B29C 67/0051 (20130101) B29C 67/0066 (20130101) B29C 2045/0079 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/002 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) Original (OR) Class B32B 15/20 (20130101) B32B 2307/304 (20130101) B32B 2307/306 (20130101) B32B 2607/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/00 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/12 (20130101) C25D 3/562 (20130101)
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09731822 — Modular testable release mechanism

US 09731822	Erian
FUNDED BY	Department of Defense (DOD) Missile Defense Agency (MDA)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Hany F. Erian (Huntington Beach, California)
ABSTRACT	A modular testable release mechanism for payloads incorporates a housing and a flyaway plate separably engaged to the housing. A plurality of symmetrically positioned ejection springs are compressed between the flyaway plate and housing in an engaged position. A bolt extends through a first bore in the flyaway plate and is releasably secured in an actuator mounted on the housing symmetrically surrounded by the ejection springs. The flyaway plate is held in the engaged position with the housing by the bolt.
FILED	Wednesday, March 30, 2016
APPL NO	15/085735
ART UNIT	3652 — Material and Article Handling
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/12 (20130101) Original (OR) Class
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09731982 — Surface modified ceramic filter

US 09731982	Adams
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	UNIVERSITY OF KANSAS (Lawrence, Kansas)
ASSIGNEE(S)	UNIVERSITY OF KANSAS (Lawrence, Kansas)
INVENTOR(S)	Craig D. Adams (North Logan, Utah)
ABSTRACT	A porous ceramic filter having one or more coatings of elemental or compounds of iron, manganese, aluminum, titanium, or mixtures thereof deposited on the surface of the pores.
FILED	Friday, November 16, 2012
APPL NO	13/679800
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 39/20 (20130101) B01D 39/2093 (20130101) B01D 2239/0478 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/288 (20130101) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 41/50 (20130101) C04B 41/85 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/37 (20150501)
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09732132 — Therapeutic compositions and methods for disorders associated with neuronal degeneration

US 09732132	Rex et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Telemedicine and Advanced Technology Research Center (TATRC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Tonia S. Rex (Goodlettsville, Tennessee); Timothy A. Sullivan (Savannah, Georgia)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Tonia S. Rex (Goodlettsville, Tennessee); Timothy A. Sullivan (Savannah, Georgia)
ABSTRACT	Disclosed are isolated mutant erythropoietin (EPO) polypeptides, functional fragment thereof, nucleic acid encoding such peptides, vectors including such nucleic acids and compositions including such peptides and nucleic acids. The mutant EPO peptides are unique in that they include a substitution at amino acid position number 76, such as a glutamic acid for arginine substitution at position 76. This substitution inhibits erythropoietic activity while retaining their neuroprotection. Also disclosed are methods of treating or inhibiting neuronal degeneration, reducing or inhibiting one or more symptoms associated with neuronal degeneration and/or glaucoma in a subject. The methods include administering a therapeutically effective amount of a isolated mutant erythropoietin EPO polypeptide, an expression vector encoding such a mutant erythropoietin EPO polypeptide, a viral particle including an expression vector, or a composition, thereby treating or inhibiting neuronal degeneration in the subject.
FILED	Friday, January 13, 2012
APPL NO	13/979451
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/505 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) C12N 7/00 (20130101) C12N 15/00 (20130101) C12N 15/10 (20130101) C12N 15/86 (20130101)
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09732235 — Corrosion resistant hybrid silanized epoxy ester resins, coatings and surface pre-treatment formulations

US 09732235	Iroh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	University of Cincinnati (Cincinnati, Ohio)
ASSIGNEE(S)	University Of Cincinnati (Cincinnati, Ohio)
INVENTOR(S)	Jude Iroh (Mason, Ohio); Jaspreet S. Beemat (Maricopa, Arizona)
ABSTRACT	A self-healing coating composition for use on metals includes a polyurea, an epoxy ester unsaturated resin, a combination of amine terminated siloxane and epoxy terminated siloxane and an organoclay. The polyurea is a water-soluble, aromatic polyurea and likewise, the epoxy ester is a water-soluble, aromatic epoxy ester. The coating composition is formed in a non-volatile solvent, such as N-Methylpyrrolidone. It can be applied to a metal surface and cured at room temperature to form a coating that is resistant to corrosion. Further the coating self-heals in a manner similar to a chromate coating.
FILED	Tuesday, June 09, 2015
APPL NO	14/734089
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/3243 (20130101) C08G 18/7671 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/346 (20130101) C08K 3/346 (20130101) C08K 3/346 (20130101) Compositions of Macromolecular Compounds C08L 63/10 (20130101) C08L 75/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/08 (20130101) Original (OR) Class C09D 163/10 (20130101) C09D 163/10 (20130101) C09D 175/02 (20130101) C09D 175/04 (20130101) C09D 175/04 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 11/10 (20130101)
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09732273 — Quantum dots, rods, wires, sheets, and ribbons, and uses thereof

US 09732273	Yan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)	Hao Yan (Chandler, Arizona); Zhengtao Deng (Tempe, Arizona); Yan Liu (Chandler, Arizona)
ASSIGNEE(S)	Arizona Board of Regents (Scottsdale, Arizona)
INVENTOR(S)	Hao Yan (Chandler, Arizona); Zhengtao Deng (Tempe, Arizona); Yan Liu (Chandler, Arizona)
ABSTRACT	Described are Zn_xCd_1-xS_ySe_1-y/ZnS_zSe_1-zcore/shell nanocrystals, CdTe/CdS/ZnS core/shell/shell nanocrystals, optionally doped Zn(S,Se,Te) nano- and quantum wires, and SnS quantum sheets or ribbons, methods for making the same, and their use in biomedical and photonic applications, such as sensors for analytes in cells and preparation of field effect transistors.
FILED	Thursday, October 29, 2015
APPL NO	14/926733
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 10/00 (20130101) B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) C01B 19/007 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 9/08 (20130101) C01G 19/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/04 (20130101) C01P 2004/16 (20130101) C01P 2004/17 (20130101) C01P 2004/64 (20130101) C01P 2004/86 (20130101) C01P 2004/88 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/08 (20130101) C09K 11/54 (20130101) C09K 11/565 (20130101) C09K 11/574 (20130101) C09K 11/661 (20130101) C09K 11/0811 (20130101) C09K 11/883 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/22 (20130101) H01L 29/122 (20130101) H01L 29/127 (20130101) H01L 29/0669 (20130101) H01L 29/775 (20130101) H01L 29/66977 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/294 (20150115) Y10T 428/12431 (20150115)
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09732294 — Renewable high density turbine and diesel fuels

US 09732294	Harvey
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin G. Harvey (Ridgecrest, California)
ABSTRACT	A method for synthesizing cyclic hydrocarbons with linear hydrocarbon side chains from a renewable source, or biomass by naturally occurring or bioengineered fungal strains, or hydrodistillation of plants.
FILED	Wednesday, September 02, 2015
APPL NO	14/843840
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/42 (20130101) C10G 45/44 (20130101) C10G 45/60 (20130101) C10G 2300/308 (20130101) C10G 2300/1014 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) Original (OR) Class C10L 2200/0469 (20130101) C10L 2270/04 (20130101) C10L 2270/026 (20130101) C10L 2290/26 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) C12P 7/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/13 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/10 (20151101) Y02P 30/20 (20151101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/678 (20130101)
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09732295 — Diesel and jet fuels based on the oligomerization of butene

US 09732295	Wright et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Michael E Wright (Tremonton, Utah); Benjamin G Harvey (Ridgecrest, California); Roxanne L Quintana (Ridgecrest, California)
ABSTRACT	A renewable biofuel based on a highly efficient batch catalysis methodology for conversion of 1-butene to a new class of potential jet fuel blends. By tuning the catalyst and then using the dimer produced, the carbon use is about 95% or greater. This latter point will be particularly important in the future, where the source of raw materials (i.e., biomass/biofeedstock) is limited.
FILED	Thursday, October 01, 2015
APPL NO	14/872418
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 1/08 (20130101) Original (OR) Class C10L 2200/0469 (20130101) C10L 2270/04 (20130101) C10L 2270/026 (20130101) C10L 2290/543 (20130101)
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09732321 — Engineered craniofacial constructs with composite scaffold

US 09732321	Bassett et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) Armed Forces Institute of Regenerative Medicine (AFIRM) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Erik Bassett (Watertown, Massachusetts); Mack Cheney (Brookline, Massachusetts); Theresa Hadlock (Concord, Massachusetts); Irina Pomerantseva (Wakefield, Massachusetts); Mark Randolph (Chelmsford, Massachusetts); Cathryn Sundback (Harvard, Massachusetts); Joseph Vacanti (Winchester, Massachusetts)
ASSIGNEE(S)	THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); MASSACHUSETTS EYE AND EAR INFIMARY (Boston, Massachusetts)
INVENTOR(S)	Erik Bassett (Watertown, Massachusetts); Mack Cheney (Brookline, Massachusetts); Theresa Hadlock (Concord, Massachusetts); Irina Pomerantseva (Wakefield, Massachusetts); Mark Randolph (Chelmsford, Massachusetts); Cathryn Sundback (Harvard, Massachusetts); Joseph Vacanti (Winchester, Massachusetts)
ABSTRACT	The present invention provides for compositions and constructs for craniofacial reconstruction implants, and methods for making and using same. Specific embodiments provide for a biocompatible scaffold having an auricular shape and a permanent bendable framework within the scaffold, wherein the permanent bendable framework allows deformation and return to pre-deformation shape, and thus maintains the auricular shape of the scaffold.
FILED	Wednesday, February 16, 2011
APPL NO	13/028725
ART UNIT	3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/04 (20130101) A61L 27/24 (20130101) A61L 27/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0655 (20130101) Original (OR) Class C12N 5/0663 (20130101) C12N 2501/15 (20130101) C12N 2502/1317 (20130101) C12N 2533/54 (20130101)
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09732392 — Modular sensor architecture for cell based biosensors

US 09732392	Leonard et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Joshua N. Leonard (Wilmette, Illinois); Rachel M. Dudek (Evanston, Illinois); Nichole M. Daringer (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Joshua N. Leonard (Wilmette, Illinois); Rachel M. Dudek (Evanston, Illinois); Nichole M. Daringer (Evanston, Illinois)
ABSTRACT	The present invention provides modular extracellular sensors, nucleic acids encoding such sensors, and cells expressing such sensors, and methods of employing such sensors and cells for detecting extracellular ligands. In certain embodiments, the extracellular sensors comprise a ligand binding domain, a transmembrane domain, a protease domain, a protease cleavage site, and a transcription factor. In other embodiments, a pair of extracellular receptors is provided where both receptors contain a ligand binding domain and transmembrane domain, and one receptor contains a protease cleavage site and a transcription factor and the other receptor contains a protease domain.
FILED	Friday, August 03, 2012
APPL NO	14/236974
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/582 (20130101) G01N 33/6872 (20130101)
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09732619 — Retaining rings for turbomachine disk and coverplate assemblies

US 09732619	Wilson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Ross Wilson (South Glastonbury, Connecticut); Dwayne K. Mecklenburg (Stafford Springs, Connecticut); Zachary Mott (Glastonbury, Connecticut); David R. Griffin (Tolland, Connecticut)
ABSTRACT	A retaining ring for a turbomachine disk and coverplate assembly includes a ring body defining a coverplate interface side and an opposed disk lip interface side. A flow feature is defined by the ring body on the coverplate interface side to allow airflow between the turbomachine disk coverplate and the ring body such that a pocket defined between the coverplate and the turbomachine disk is in fluid communication with a conditioning flow pathway through the retaining ring.
FILED	Tuesday, March 31, 2015
APPL NO	14/674084
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/081 (20130101) F01D 5/082 (20130101) F01D 5/3007 (20130101) Original (OR) Class F01D 5/3015 (20130101) F01D 25/12 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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09732620 — Snap in platform damper and seal assembly for a gas turbine engine

US 09732620	Hough
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Matthew A. Hough (West Hartford, Connecticut)
ABSTRACT	A turbine assembly includes a first turbine blade circumferentially adjacent to a second turbine blade. The first turbine blade includes a first platform with a first underplatform surface. The second turbine blade includes a second platform with a second underplatform surface. The first underplatform surface and the second underplatform surface at least partially defines a cavity. A damper with a platform rub surface is included adjacent the first underplatform surface and the second underplatform surface. A seal is included with a forward portion, an aft portion, and a damper interface portion therebetween. The damper interface portion extends along a damper underside and the forward portion and the aft portion adjacent the first underplatform surface and the second underplatform surface.
FILED	Wednesday, July 23, 2014
APPL NO	14/339019
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/22 (20130101) F01D 5/323 (20130101) F01D 5/3007 (20130101) F01D 11/006 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/96 (20130101)
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09732624 — Hot environment vane angle measurement

US 09732624	Singh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S)	HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina)
INVENTOR(S)	Bhupindar Singh (West Hartford, Connecticut); Gregory DiVincenzo (Wethersfield, Connecticut)
ABSTRACT	A turbine is provided and includes an outer duct, a turbine casing formed to define a turbine interior, the turbine casing being disposed within the outer duct to define an annulus, a vane element pivotably coupled to the turbine casing via a spindle to extend spanwise into the turbine interior and a sensor element supportively coupled to the outer duct and configured to sense a characteristic of the spindle within the annulus from which a pivot angle of the vane element is derivable.
FILED	Thursday, July 10, 2014
APPL NO	14/328252
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) F01D 17/00 (20130101) F01D 17/02 (20130101) F01D 17/10 (20130101) F01D 17/12 (20130101) F01D 17/14 (20130101) F01D 17/16 (20130101) F01D 17/162 (20130101) F01D 21/003 (20130101) Original (OR) Class F01D 25/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/74 (20130101)
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09732630 — Oil scoop and shaft with axially-oriented hole

US 09732630	Lucas
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	James L. Lucas (Hamden, Connecticut)
ABSTRACT	Aspects of the disclosure are directed to a system associated with an engine of an aircraft. The system includes a shaft configured with at least one axially-oriented hole, and an oil scoop configured to receive oil and provide the oil to the shaft, wherein the oil scoop is manufactured independently from the shaft, and wherein the oil scoop includes at least one retention mechanism for coupling to the shaft after the at least one axially-oriented hole is created in the shaft.
FILED	Friday, March 27, 2015
APPL NO	14/671681
ART UNIT	3654 — Material and Article Handling
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/16 (20130101) F01D 25/18 (20130101) F01D 25/183 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/80 (20130101)
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09732988 — Thermal storage device including a plurality of discrete canisters

US 09732988	Spero et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Thermal Storage Systems (Los Angeles, California)
ASSIGNEE(S)	Thermal Storage Systems (Los Angeles, California)
INVENTOR(S)	Alan J. Spero (Ramona, California); Frank Stephen Wyle (Los Angeles, California); James H. Cohen (Glendale, California)
ABSTRACT	A novel thermal storage device is made up of a plurality of thermal storage canisters. The canisters are in thermal contact with one another so as to form a single thermal storage body. Because the thermal storage device can be broken down into a plurality of discrete thermal storage canisters, it is portable and has a high thermal storage capacity. In a particular embodiment, each canister contains a metal phase change material. In a more particular embodiment, the canisters each have a concave region such that when the canisters are assembled the concave regions, together, define a solar receiver.
FILED	Thursday, May 30, 2013
APPL NO	13/906178
ART UNIT	3743 — Material and Article Handling
CURRENT CPC	Producing or Use of Heat Not Otherwise Provided For F24J 2/46 (20130101) Original (OR) Class
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09733035 — Retractable supressor

US 09733035	Davis
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jason M. Davis (Loogootee, Indiana)
ABSTRACT	A variety of apparatuses and associated methods are provided for providing a retractable suppressor system for gas generator systems such as a firearm. One embodiment includes a suppressor system that includes a retractable structure and housing, a fixed baffle, floating baffles, and springs to displace the floating baffles within the suppressor as the suppressor is extended from the housing along a gas generator system, e.g. a barrel of a firearm and thereby enclose the barrel within the suppressor. Embodiments of the invention permit full retraction, partial retraction/extension, or full extension of an exemplary suppressor with respect to an emission section of the gas generator e.g., firearm muzzle. Embodiments of the invention include an external latch which enables an operator to latch or unlatch the suppressor as it moves from one position to another and prevents accidental activation. Embodiments of the invention are configured to operate with accessory mounting systems.
FILED	Tuesday, November 17, 2015
APPL NO	14/943334
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/30 (20130101) F41A 21/34 (20130101) Original (OR) Class
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09733125 — Resonator enhanced raman spectroscopy

US 09733125	Liu et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC) National Institute for Occupational Safety and Health (NIOSH) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania); Washington University (St. Louis, Missouri)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania); Washington University (St. Louis, Missouri)
INVENTOR(S)	Zhiwen Liu (State College, Pennsylvania); Lan Yang (Saint Louis, Missouri); Perry Edwards (State College, Pennsylvania); Corey Janisch (University Park, Pennsylvania); Bo Peng (Saint Louis, Missouri); Sahin Ozdemir (University City, Missouri)
ABSTRACT	Embodiments of the invention provide Raman spectroscopy methods and devices that exploit high quality factor (Q) resonators to enhance Raman signal by several orders of magnitude over the signal typically expected for Raman methods. Embodiments typically include one or more resonators, typically microtoroid microresonators. Embodiments also take advantage of Rayleigh scattering using these microresonators. Embodiments may be particularly useful for non-labeled nanoparticle sensing.
FILED	Wednesday, September 25, 2013
APPL NO	14/431080
ART UNIT	2877 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/26 (20130101) G01J 3/44 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 3/0224 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101)
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09733185 — Gradient structures interfacing microfluidics and nanofluidics, methods for fabrication and uses thereof

US 09733185	Cao et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Princeton University (Princeton, New Jersey)
ASSIGNEE(S)	Princeton University (Princeton, New Jersey)
INVENTOR(S)	Han Cao (San Diego, California); Jonas O. Tegenfeldt (Lund, Sweden); Stephen Chou (Princeton, New Jersey); Robert H. Austin (Princeton, New Jersey)
ABSTRACT	The present invention relates to a device for interfacing nanofluidic and microfluidic components suitable for use in performing high throughput macromolecular analysis. Diffraction gradient lithography (DGL) is used to form a gradient interface between a microfluidic area and a nanofluidic area. The gradient interface area reduces the local entropic barrier to nanochannels formed in the nanofluidic area. In one embodiment, the gradient interface area is formed of lateral spatial gradient structures for narrowing the cross section of a value from the micron to the nanometer length scale. In another embodiment, the gradient interface area is formed of a vertical sloped gradient structure. Additionally, the gradient structure can provide both a lateral and vertical gradient.
FILED	Tuesday, November 13, 2012
APPL NO	13/675685
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/12 (20130101) B01L 2200/027 (20130101) B01L 2200/0663 (20130101) B01L 2300/0654 (20130101) B01L 2300/0896 (20130101) B01L 2400/086 (20130101) B01L 2400/0415 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00119 (20130101) B81C 2201/0157 (20130101) B81C 2201/0159 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class G01N 33/48721 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/2008 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115)
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09733460 — Method and apparatus for microscopic imaging

US 09733460	Kang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Dongkyun Kang (Somerville, Massachusetts); Minkyu Kim (Boston, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts)
ABSTRACT	Apparatus and method for facilitating a microscopic imaging of at least one anatomical structure can be provided. For example, with a spectrally-encoded confocal microscopy (SECM) system, it is possible to provide at least one first electro-magnetic radiation to the anatomical structure(s). In addition, a mobile device can be provided which can communicate with the SECM system. The mobile device can have a sensor arrangement, and with such sensor arrangement, it is possible to receive at least one second electro-magnetic radiation that is based on the first radiation(s) from at least one section of the SECM system. The mobile device can further include a computer arrangement, with which it is possible to display at least one portion of the anatomical structure(s) as a microscopic image based on the second radiation(s) received by the sensor arrangement.
FILED	Wednesday, January 07, 2015
APPL NO	15/110388
ART UNIT	2486 — Recording and Compression
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/1025 (20130101) A61B 5/0066 (20130101) A61B 5/0068 (20130101) A61B 5/0084 (20130101) A61B 5/6898 (20130101) A61B 2560/045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4795 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0008 (20130101) Original (OR) Class G02B 21/0028 (20130101) G02B 21/0064 (20130101) G02B 23/2453 (20130101) Telephonic Communication H04M 1/215 (20130101)
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09733498 — Disk resonator based on a composite structure

US 09733498	Luo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Oracle International Corporation (Redwood Shores, California)
ASSIGNEE(S)	ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California)
INVENTOR(S)	Ying Luo (San Diego, California); Xuezhe Zheng (San Diego, California); Shiyun Lin (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT	An optical modulator is described. This optical modulator may be implemented using silicon-on-insulator (SOI) technology. In particular, the optical modulator may include a carrier-accumulation-type micro-disk resonator fabricated using optical waveguides having a composite structure. Moreover, the composite structure may embed a metal-oxide semiconductor capacitor in the disk resonator. For example, the composite structure may include polysilicon disposed on an oxide layer, which is disposed on a silicon layer in an SOI platform. The optical modulator may have high modulation efficiency and high-speed operation. In addition, the optical modulator may have a compact footprint with low power consumption.
FILED	Friday, October 09, 2015
APPL NO	14/880045
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/1228 (20130101) G02B 6/12004 (20130101) G02B 2006/12061 (20130101) G02B 2006/12142 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) Original (OR) Class G02F 2001/0151 (20130101) G02F 2202/104 (20130101)
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09733543 — Sub-volt drive 100 GHz bandwidth electro-optic modulator

US 09733543	Dagli
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Nadir Dagli (Goleta, California)
ABSTRACT	Electro-optical modulators and methods of fabrication are disclosed. An electro-optical modulator includes a Mach-Zehnder interferometer formed in a substrate removed semiconductor layer and a coplanar waveguide. Signals from the coplanar waveguide are capacitively coupled to the Mach-Zehnder interferometer through first and second dielectric layers.
FILED	Wednesday, October 05, 2016
APPL NO	15/286275
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/42 (20130101) G02B 6/125 (20130101) G02B 6/132 (20130101) G02B 2006/1204 (20130101) G02B 2006/12047 (20130101) G02B 2006/12054 (20130101) G02B 2006/12078 (20130101) G02B 2006/12128 (20130101) G02B 2006/12142 (20130101) G02B 2006/12159 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0121 (20130101) G02F 1/01708 (20130101) G02F 1/2255 (20130101) Original (OR) Class G02F 1/2257 (20130101) G02F 2001/212 (20130101) G02F 2201/12 (20130101) G02F 2202/20 (20130101) G02F 2202/42 (20130101)
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09733545 — Nonlinear metasurfaces based on plasmonic resonators coupled to intersubband transitions

US 09733545	Belkin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Mikhail Belkin (Austin, Texas); Andrea Alu (Austin, Texas); Jongwon Lee (Austin, Texas); Mykhailo Tymchenko (Austin, Texas)
ABSTRACT	A nonlinear metasurface structure including a multi-quantum-well layer designed for a nonlinear response for a desired nonlinear optical process and an array of nanoantennas coupled to the intersubband transitions of the multi-quantum-well layer. Each nanoantenna in the array is designed to have electromagnetic resonances at or close to all input and output frequencies of a given nonlinear optical process. Nanoantennas allow efficient coupling of any incident and outgoing light polarizations to intersubband transitions. Nanoantennas may further provide significant field enhancement in the multi-quantum-well layer. As a result, the nonlinear metasurface structure can be designed to produce a highly nonlinear response for any polarization and angle of incidence of incoming and outgoing waves in a nonlinear optical process. Due to their very larger nonlinear response, efficient frequency conversion can be produced in these metasurfaces without the stringent phase-matching constraints of bulk nonlinear crystals.
FILED	Thursday, July 30, 2015
APPL NO	14/814176
ART UNIT	2872 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/017 (20130101) G02F 1/3501 (20130101) G02F 1/3556 (20130101) Original (OR) Class G02F 2001/01775 (20130101) G02F 2001/3505 (20130101) G02F 2001/3507 (20130101) G02F 2202/30 (20130101) G02F 2202/108 (20130101) G02F 2203/10 (20130101)
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09733685 — Temperature-aware microprocessor voltage management

US 09733685	Lefurgy et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Charles R. Lefurgy (Austin, Texas); Karthick Rajamani (Austin, Texas); Richard F. Rizzolo (Red Hook, New York); Malcolm S. Allen-Ware (Tuscon, Arizona)
ABSTRACT	A method, system, and computer program product for controlling power supplied to a processor is disclosed. A voltage regulator is set to a first voltage regulator set point, wherein the first voltage regulator set point provides a first load line for operation of the processor. A change in an operation of the processor from a first operating condition along the first load line to a second operating condition along the first load line is determined. The voltage regulator is the set to a second voltage regulator set point and the processor is operated at a third operating condition on a second load line corresponding to the second voltage regulator set point.
FILED	Monday, December 14, 2015
APPL NO	14/967929
ART UNIT	2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Systems for Regulating Electric or Magnetic Variables G05F 1/625 (20130101) Electric Digital Data Processing G06F 1/26 (20130101) Original (OR) Class
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09733995 — Scalable synchronization mechanism for distributed memory

US 09733995	Cole et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Clement T. Cole (Chelmford, Massachusetts); James Dinan (Hudson, Massachusetts); Gabriele Jost (Santa Clara, California); Stanley C. Smith (Hillsboro, Oregon); Robert W. Wisniewski (Ossining, New York); Keith D. Underwood (Albuquerque, New Mexico)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Clement T. Cole (Chelmford, Massachusetts); James Dinan (Hudson, Massachusetts); Gabriele Jost (Santa Clara, California); Stanley C. Smith (Hillsboro, Oregon); Robert W. Wisniewski (Ossining, New York); Keith D. Underwood (Albuquerque, New Mexico)
ABSTRACT	A method comprising receiving control information at a first processing element from a second processing element, synchronizing objects within a shared global memory space of the first processing element with a shared global memory space of a second processing element in response to receiving the control information and generating a completion event indicating the first processing element has been synchronized with the second processing element.
FILED	Wednesday, December 17, 2014
APPL NO	14/573133
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class G06F 12/06 (20130101) G06F 12/0692 (20130101) G06F 2212/1016 (20130101)
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09734069 — Multicast tree-based data distribution in distributed shared cache

US 09734069	Steely, Jr. et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Simon C. Steely, Jr. (Hudson, New Hampshire); William C. Hasenplaugh (Boston, Massachusetts); Samantika S. Sury (Westford, Massachusetts)
ABSTRACT	Systems and methods for multicast tree-based data distribution in a distributed shared cache. An example processing system comprises: a plurality of processing cores, each processing core communicatively coupled to a cache; a tag directory associated with caches of the plurality of processing cores; a shared cache associated with the tag directory; a processing logic configured, responsive to receiving an invalidate request with respect to a certain cache entry, to: allocate, within the shared cache, a shared cache entry corresponding to the certain cache entry; transmit, to at least one of: a tag directory or a processing core that last accessed the certain entry, an update read request with respect to the certain cache entry; and responsive to receiving an update of the certain cache entry, broadcast the update to at least one of: one or more tag directories or one or more processing cores identified by a tag corresponding to the certain cache entry.
FILED	Thursday, December 11, 2014
APPL NO	14/567026
ART UNIT	2135 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 12/084 (20130101) Original (OR) Class G06F 12/0815 (20130101) G06F 12/0822 (20130101) G06F 2212/281 (20130101) G06F 2212/1021 (20130101)
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09734414 — Unified framework for precise vision-aided navigation

US 09734414	Samarasekera et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) United States Marine Corps (USMC)
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI International (Menlo Park, California)
INVENTOR(S)	Supun Samarasekera (Princeton, New Jersey); Rakesh Kumar (West Windsor, New Jersey); Taragay Oskiper (East Windsor, New Jersey); Zhiwei Zhu (Plainsboro, New Jersey); Oleg Naroditsky (Princeton, New Jersey); Harpreet Sawhney (Princeton Junction, New Jersey)
ABSTRACT	A system and method for efficiently locating in 3D an object of interest in a target scene using video information captured by a plurality of cameras. The system and method provide for multi-camera visual odometry wherein pose estimates are generated for each camera by all of the cameras in the multi-camera configuration. Furthermore, the system and method can locate and identify salient landmarks in the target scene using any of the cameras in the multi-camera configuration and compare the identified landmark against a database of previously identified landmarks. In addition, the system and method provide for the integration of video-based pose estimations with position measurement data captured by one or more secondary measurement sensors, such as, for example, Inertial Measurement Units (IMUs) and Global Positioning System (GPS) units.
FILED	Tuesday, August 25, 2015
APPL NO	14/835080
ART UNIT	2451 — Computer Networks
CURRENT CPC	Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 1/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/005 (20130101) G01C 21/165 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) G06K 9/00791 (20130101) Original (OR) Class G06K 9/3216 (20130101) G06K 9/4642 (20130101) G06K 9/6215 (20130101) Image Data Processing or Generation, in General G06T 7/74 (20170101) Pictorial Communication, e.g Television H04N 13/0239 (20130101) H04N 2013/0081 (20130101)
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09734586 — Collision prediction

US 09734586	Luo et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	The Schepens Eye Research Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	The Schepens Eye Research Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Gang Luo (Boston, Massachusetts); Eliezer Peli (Boston, Massachusetts); Shrinivas Pundlik (Boston, Massachusetts)
ABSTRACT	In some implementations, there is provided a method. The method may include receiving data characterizing a plurality of digital video frames; detecting a plurality of features in each of the plurality of digital video frames; determining, from the detected features, a local scale change and a translational motion of one or more groups of features between at least a pair of the plurality of digital video frames; and calculating a likelihood of collision. Related apparatus, systems, techniques, and articles are also described.
FILED	Friday, September 20, 2013
APPL NO	14/430108
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) G06K 9/00805 (20130101) G06K 9/00825 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 7/2033 (20130101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/20076 (20130101) G06T 2207/30261 (20130101) G06T 2210/21 (20130101) G06T 2219/2016 (20130101)
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09734730 — Multi-modal modeling of temporal interaction sequences

US 09734730	Divakaran et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI International (Menlo Park, California)
INVENTOR(S)	Ajay Divakaran (Monmouth Junction, New Jersey); Behjat Siddiquie (Plainsboro, New Jersey); Saad Khan (Hamilton, New Jersey); Jeffrey Lubin (Princeton, New Jersey); Harpreet S. Sawhney (Princeton Junction, New Jersey)
ABSTRACT	A multi-modal interaction modeling system can model a number of different aspects of a human interaction across one or more temporal interaction sequences. Some versions of the system can generate assessments of the nature or quality of the interaction or portions thereof, which can be used to, among other things, provide assistance to one or more of the participants in the interaction.
FILED	Thursday, January 31, 2013
APPL NO	13/755775
ART UNIT	3715 — Amusement and Education Devices
CURRENT CPC	Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/00 (20130101) Original (OR) Class
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09734823 — Method and system for efficient spoken term detection using confusion networks

US 09734823	Kingsbury et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Brian E. D. Kingsbury (Cortlandt Manor, New York); Hong-Kwang Kuo (Pleasantville, New York); Lidia Mangu (Yorktown Heights, New York); Hagen Soltau (Yorktown Heights, New York)
ABSTRACT	Systems and methods for spoken term detection are provided. A method for spoken term detection, comprises receiving phone level out-of-vocabulary (OOV) keyword queries, converting the phone level OOV keyword queries to words, generating a confusion network (CN) based keyword searching (KWS) index, and using the CN based KWS index for both in-vocabulary (IV) keyword queries and the OOV keyword queries.
FILED	Thursday, August 27, 2015
APPL NO	14/837876
ART UNIT	2657 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 13/08 (20130101) G10L 15/02 (20130101) G10L 15/083 (20130101) Original (OR) Class G10L 2015/025 (20130101) G10L 2015/085 (20130101)
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09734946 — Superparamagnetic colloids with enhanced charge stability for high quality magnetically tunable photonic structures

US 09734946	Yin et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Yadong Yin (Riverside, California); Yongxing Hu (Riverside, California)
ABSTRACT	A method of stabilizing electromagnetically charged particles, which includes coating electromagnetically charged particles with a protective layer; and etching the protective layer to produce a porous protective layer on the electromagnetically charged.
FILED	Friday, November 09, 2012
APPL NO	14/357251
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/14 (20130101) B01J 13/20 (20130101) B01J 13/0047 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Optical Elements, Systems, or Apparatus G02B 2006/1213 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0018 (20130101) H01F 1/445 (20130101) H01F 41/005 (20130101) Original (OR) Class
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09734977 — Image intensifier with indexed compliant anode assembly

US 09734977	Costello et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Warfare Center (NAWC)
APPLICANT(S)	Intevac, Inc. (Santa Clara, California)
ASSIGNEE(S)	INTEVAC, INC. (Santa Clara, California)
INVENTOR(S)	Kenneth Costello (Union City, California); Kevin Roderick (San Jose, California)
ABSTRACT	An image intensifier and a method of fabrication are disclosed. The image intensifier contains a photocathode assembly (120) including a vacuum window to generate photoelectrons in response to light, a vacuum package (110) and an anode assembly (130) to receive the photoelectrons. The anode assembly is mounted to the vacuum package via a compliant, springy, support structure (160). The anode additionally includes one or more insulating spacers (140) on the surface facing the photocathode so as to precisely index the position of the anode assembly with respect to the photocathode surface. The photocathode and vacuum window assembly is pressed into the vacuum package to generate a sealed leak tight vacuum envelope. During the photocathode assembly to vacuum package assembly pressing operation, the inner surface of the photocathode assembly contacts the insulating spacer/spacers of the anode assembly, thereby compressing the compliant support structure. This structure and assembly method result in a precisely indexed photocathode to anode assembly sealed image intensifier.
FILED	Thursday, July 16, 2015
APPL NO	14/801807
ART UNIT	2879 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 1/34 (20130101) Original (OR) Class H01J 9/18 (20130101) H01J 31/26 (20130101)
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09735022 — Arrays of long nanostructures in semiconductor materials and methods thereof

US 09735022	Yi et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Alphabet Energy, Inc. (Hayward, California)
ASSIGNEE(S)	ALPHABET ENERGY, INC. (Hayward, California)
INVENTOR(S)	Mingqiang Yi (San Pablo, California); Matthew L. Scullin (San Francisco, California); Gabriel Matus (San Francisco, California); Dawn L. Hilken (Pleasant Hill, California); Chii Guang Lee (Fremont, California); Sylvain Muckenhirn (Santa Barbara, California)
ABSTRACT	An array of nanowires and method thereof. The array of nanowires includes a plurality of nanowires. The plurality of nanowires includes a plurality of first ends and a plurality of second ends respectively. For each of the plurality of nanowires, a corresponding first end selected from the plurality of first ends and a corresponding second end selected from the plurality of second ends are separated by a distance of at least 200 μm. All nanowires of the plurality of nanowires are substantially parallel to each other.
FILED	Thursday, December 11, 2014
APPL NO	14/567793
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3081 (20130101) H01L 21/3085 (20130101) H01L 21/3086 (20130101) Original (OR) Class H01L 27/16 (20130101) H01L 29/0676 (20130101) H01L 31/035227 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2913 (20150115) Y10T 428/24802 (20150115) Y10T 428/249924 (20150401)
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09735088 — Systems and methods for thermal control of integrated circuits

US 09735088	Woolrich et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Kyle A. Woolrich (El Segundo, California); Jonathan M. Allison (Redondo Beach, California); Thomas Rust, III (Manhattan Beach, California); Robert E. Silhavy (Torrance, California)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Kyle A. Woolrich (El Segundo, California); Jonathan M. Allison (Redondo Beach, California); Thomas Rust, III (Manhattan Beach, California); Robert E. Silhavy (Torrance, California)
ABSTRACT	A system includes a carrier defining a plurality of channels. The system includes an integrated circuit (IC) die having a first side and having a second side opposite the first side. The second side of the IC die is coupled to the carrier. The system includes a die attach layer between the carrier and the second side of the IC die. The die attach layer defines one or more openings that enable a fluid to flow from the carrier to the second side of the IC die.
FILED	Tuesday, December 08, 2015
APPL NO	14/963181
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/50 (20130101) H01L 23/46 (20130101) Original (OR) Class H01L 27/0296 (20130101)
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09735306 — Wüstite-based photoelectrodes with lithium, hydrogen, sodium, magnesium, manganese, zinc and nickel additives

US 09735306	Carter et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Emily Ann Carter (Belle Mead, New Jersey); Maytal Caspary Toroker (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); TECHNION RESEARCH and DEVELOPMENT FOUNDATION, LTD (Haifa, Israel)
INVENTOR(S)	Emily Ann Carter (Belle Mead, New Jersey); Maytal Caspary Toroker (Princeton, New Jersey)
ABSTRACT	A photoelectrode, photovoltaic device and photoelectrochemical cell and methods of making are disclosed. The photoelectrode includes an electrode at least partially formed of FeO combined with at least one of lithium, hydrogen, sodium, magnesium, manganese, zinc, and nickel. The electrode may be doped with at least one of lithium, hydrogen, and sodium. The electrode may be alloyed with at least one of magnesium, manganese, zinc, and nickel.
FILED	Tuesday, May 21, 2013
APPL NO	13/899049
ART UNIT	1757 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/07 (20130101) H01L 31/18 (20130101) Original (OR) Class H01L 31/032 (20130101) H01L 31/072 (20130101) H01L 31/0264 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101)
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09735344 — Hybrid hall effect magnetoelectronic gate

US 09735344	Johnson
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Corps of Engineers (USACE) Engineer Research and Development Center (ERDC) Geospatial Research Laboratory (GRL) Department of the Navy (DON) Naval Research Laboratory (NRL) Office of Naval Research (ONR)
APPLICANT(S)	Mark B Johnson (Potomac, Maryland)
ASSIGNEE(S)
INVENTOR(S)	Mark B Johnson (Potomac, Maryland)
ABSTRACT	Hybrid Hall Effect Devices implemented with Spin Transfer Torque write capability are configured as magnetoelectronic (ME) devices. These devices are useable as circuit building blocks in reconfigurable processing systems, including as logic circuits, non-volatile switches and memory cells.
FILED	Monday, August 29, 2016
APPL NO	15/250779
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/06 (20130101) Original (OR) Class H01L 43/10 (20130101) Pulse Technique H03K 17/90 (20130101) H03K 19/1776 (20130101) H03K 19/017581 (20130101)
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09735355 — Electrically actuated switch

US 09735355	Williams
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (Houston, Texas)
ASSIGNEE(S)	Hewlett Packard Enterprise Development LP (Houston, Texas)
INVENTOR(S)	R. Stanley Williams (Portola Valley, California)
ABSTRACT	An electrically actuated switch comprises a first electrode, a second electrode, and an active region disposed therebetween. The active region comprises at least one primary active region comprising at least one material that can be doped or undoped to change its electrical conductivity, and a secondary active region comprising at least one material for providing a source/sink of ionic species that act as dopants for the primary active region(s). Methods of operating the switch are also provided.
FILED	Friday, February 14, 2014
APPL NO	14/181436
ART UNIT	2815 — Semiconductors/Memory
CURRENT CPC	Static Stores G11C 13/0007 (20130101) G11C 13/0009 (20130101) G11C 2213/52 (20130101) G11C 2213/53 (20130101) G11C 2213/56 (20130101) G11C 2213/77 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/2463 (20130101) H01L 45/08 (20130101) Original (OR) Class H01L 45/14 (20130101) H01L 45/145 (20130101) H01L 45/146 (20130101) H01L 45/147 (20130101) H01L 45/1206 (20130101) H01L 45/1233 (20130101) Pulse Technique H03K 17/00 (20130101)
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09735466 — Advanced composite radome and method of manufacturing

US 09735466	Johnson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Ebert Composites Corporation (Chula Vista, California)
ASSIGNEE(S)	Ebert Composites Corporation (Chula Vista, California)
INVENTOR(S)	David W. Johnson (San Diego, California); Scott A. Garrett (San Diego, California); Stephen G. Moyers (Jamul, California)
ABSTRACT	A radome for housing a radar system comprises a plurality of interconnected curved radome thermoplastic composite material panels, each curved radome thermoplastic composite material panel having a plurality of interconnecting edges, a foam core, an inner skin, an outer skin, and a plurality of three-dimensional fiber bundles tying the inner skin and the outer skin to each other through the foam core, inhibiting delamination. The radome includes a hydrophobic exterior surface that is self-cleaning and requires zero maintenance for 25 years.
FILED	Wednesday, July 16, 2014
APPL NO	14/333182
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 51/268 (20130101) B29C 65/562 (20130101) B29C 66/43 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/543 (20130101) B29C 66/721 (20130101) B29C 66/723 (20130101) B29C 66/1142 (20130101) B29C 66/7212 (20130101) B29C 66/7212 (20130101) B29C 66/7392 (20130101) B29C 66/8246 (20130101) B29C 66/72141 (20130101) B29C 66/73921 (20130101) B29C 66/83221 (20130101) B29C 67/0044 (20130101) B29C 70/086 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/12 (20130101) B29K 2027/18 (20130101) B29K 2067/003 (20130101) B29K 2067/003 (20130101) B29K 2071/00 (20130101) B29K 2077/00 (20130101) B29K 2079/085 (20130101) B29K 2081/04 (20130101) B29K 2105/256 (20130101) B29K 2309/08 (20130101) B29K 2309/08 (20130101) B29K 2995/0094 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/773 (20130101) B29L 2031/3456 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/0012 (20130101) Antennas, i.e Radio Aerials H01Q 1/42 (20130101) Original (OR) Class H01Q 1/424 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1036 (20150115)
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09735542 — Ring-modulated laser

US 09735542	Li et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Oracle International Corporation (Redwood City, California)
ASSIGNEE(S)	ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California)
INVENTOR(S)	Guoliang Li (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California); Xuezhe Zheng (San Diego, California); Ying Luo (San Diego, California)
ABSTRACT	An optical source is described. This optical source includes a semiconductor optical amplifier, with a semiconductor other than silicon, which provides a gain medium. In addition, a photonic chip, optically coupled to the semiconductor optical amplifier, includes: an optical waveguide that conveys the optical signal; and a pair of ring-resonator modulators that modulate the optical signal. Furthermore, the pair of ring-resonator modulators is included within an optical cavity in the optical source. For example, the optical cavity may be defined by a reflective coating on one edge of the semiconductor optical amplifier and a reflector on one end of the optical waveguide. Alternatively, the optical cavity may be defined by reflectors on ends of the optical waveguide.
FILED	Thursday, October 24, 2013
APPL NO	14/062624
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/12 (20130101) H01S 5/021 (20130101) H01S 5/142 (20130101) Original (OR) Class H01S 5/0261 (20130101) H01S 5/0265 (20130101) H01S 5/0287 (20130101) H01S 5/1032 (20130101)
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09735549 — Methods for forming photonic integrated circuits based on quantum cascade structures

US 09735549	Goyal et al.
FUNDED BY	Department of Defense (DOD) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Pendar Technologies, LLC (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Pendar Technologies, LLC (Cambridge, Massachusetts)
INVENTOR(S)	Anish K. Goyal (Cambridge, Massachusetts); Laurent Diehl (Somerville, Massachusetts); Christian Pfluegl (Medford, Massachusetts); Christine A. Wang (Bedford, Massachusetts); Mark Francis Witinski (Cambridge, Massachusetts)
ABSTRACT	Photonic integrated circuits (PICs) are based on quantum cascade (QC) structures. In embodiment methods and corresponding devices, a QC layer in a wave confinement region of an integrated multi-layer semiconductor structure capable of producing optical gain is depleted of free charge carriers to create a low-loss optical wave confinement region in a portion of the structure. Ion implantation may be used to create energetically deep trap levels to trap free charge carriers. Other embodiments include modifying a region of a passive, depleted QC structure to produce an active region capable of optical gain. Gain or loss may also be modified by partially depleting or enhancing free charge carrier density. QC lasers and amplifiers may be integrated monolithically with each other or with passive waveguides and other passive devices in a self-aligned manner. Embodiments overcome challenges of high cost, complex fabrication, and coupling loss involved with material re-growth methods.
FILED	Wednesday, July 27, 2016
APPL NO	15/221402
ART UNIT	2894 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/15 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/026 (20130101) H01S 5/2018 (20130101) H01S 5/2063 (20130101) H01S 5/2275 (20130101) H01S 5/3013 (20130101) H01S 5/3402 (20130101) Original (OR) Class
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09735732 — Coupled oscillators

US 09735732	Ferriss et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Mark A. Ferriss (Tarrytown, New York); Daniel J. Friedman (Sleepy Hollow, New York); Wooram Lee (Briarcliff Manor, New York); Bodhisatwa Sadhu (Fishkill, New York); Alberto Valdes Garcia (Chappaqua, New York)
ABSTRACT	An apparatus includes an oscillation ring comprising N oscillators, where N is an even integer that is greater than 3, the N oscillators connected in series in a loop by N connection nodes, each oscillator of the N oscillators comprising a pair of cross-coupled inverting amplifiers. The apparatus also includes N inductors arranged in a star configuration such that each inductor of the N inductors connects to a corresponding connection node of the oscillation ring and a common connection node of the star configuration. The apparatus may also include N capacitor banks. Each of the N capacitor banks may include a plurality of activation switches for loading a corresponding oscillator with capacitance. A method includes providing the above apparatus and activating selected activation switches to adjust an oscillation frequency for the oscillation ring toward a desired value.
FILED	Thursday, June 09, 2016
APPL NO	15/177594
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1215 (20130101) H03B 5/1218 (20130101) H03B 5/1265 (20130101) Original (OR) Class H03B 27/00 (20130101) H03B 2201/0266 (20130101) Pulse Technique H03K 3/0315 (20130101)
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09735769 — Controlling current or mitigating electromagnetic or radiation interference effects using multiple and different semi-conductive channel regions generating structures

US 09735769	Titus
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jeffrey L. Titus (Bloomington, Indiana)
ABSTRACT	Systems and methods for controlling current or mitigating electromagnetic or radiation interference effects using multiple different semi-conductive channel regions generating structures formed by multiple different semi-conductive electrical current or voltage control structures. One embodiment includes providing a first and second metal oxide semiconductor field effect transistor (MOSFET) sections formed on opposite sides of a metal-semiconductor field effect transistor (MESFET) such that operation of the MESFET modulates or controls current otherwise controlled by an electrical path of the MOSFET sections. A control system for determining when an embodiment of the invention is to be operated is also provided to include automated systems including sensors as well as manually operated systems. Automated systems can include radiation sensors as well as other control systems such as high voltage radio frequency transmitter or receiver systems. Methods of operation for a variety of modes are also provided.
FILED	Friday, October 02, 2015
APPL NO	14/873680
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/085 (20130101) H01L 29/495 (20130101) H01L 29/7802 (20130101) H01L 29/7832 (20130101) Pulse Technique H03K 17/162 (20130101) Original (OR) Class
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09735890 — Quantum communications of a two-qubit state

US 09735890	Agarwal et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	VENCORE LABS, INC. (Basking Ridge, New Jersey)
ASSIGNEE(S)	Vencore Labs, Inc. (Basking Ridge, New Jersey)
INVENTOR(S)	Anjali Agarwal (Basking Ridge, New Jersey); James Dailey (Basking Ridge, New Jersey); Paul Toliver (Basking Ridge, New Jersey); Nicholas Peters (Basking Ridge, New Jersey)
ABSTRACT	In one aspect, there is provided a method for transmitting a two-qubit state. The method includes: propagating the two-qubit state onto a transmission waveguide, wherein the propagating includes distributing the two-qubit state about a certain phase; and transmitting the two-qubit state through the transmission waveguide using a pump pulse having the certain phase, wherein the pump pulse is provided in a manner so that the transmission waveguide functions as an optical phase sensitive amplifier (OPSA).
FILED	Friday, November 20, 2015
APPL NO	14/946955
ART UNIT	2634 — Digital Communications
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Transmission H04B 10/70 (20130101) Original (OR) Class Multiplex Communication H04J 1/08 (20130101) H04J 14/00 (20130101)
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09735891 — Wavelength optimization for free-space optical communications

US 09735891	Neuner, III et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
INVENTOR(S)	Burton H. Neuner, III (San Diego, California); Ryan P. Lu (San Diego, California); Ayax D. Ramirez (Chula Vista, California); Michael G. Lovern (Chula Vista, California)
ABSTRACT	A system and method involve propagating, from one or more optical sources connected to a platform, more than one optical signal through a surrounding medium towards a reflective surface. Reflected optical signals, representing the propagated optical signals reflected off of the reflective surface, are then detected using a detection system coupled to the platform. An ideal optical wavelength is then selected for optical communication from the platform within the surrounding medium based upon one or more characteristics of the detected reflected optical signals.
FILED	Wednesday, September 30, 2015
APPL NO	14/870480
ART UNIT	2637 — Optical Communications
CURRENT CPC	Transmission H04B 10/80 (20130101) Original (OR) Class H04B 10/572 (20130101)
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09736112 — Context-aware network and situation management for crypto-partitioned networks

US 09736112	Burnett et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S)	Architecture Technology Corporation (Minneapolis, Minnesota)
INVENTOR(S)	Benjamin L. Burnett (Prior Lake, Minnesota); Deborah K. Charan (Minneapolis, Minnesota); Fabio Pozzo (Eden Prairie, Minnesota); Ranga Ramanujan (Hamel, Minnesota)
ABSTRACT	This disclosure describes a context aware scalable dynamic network whereby network information concerning network elements in an untrusted (Black) network are gathered by network sensors, stored at a network sensor collector, and sent to another network sensor collector in a trusted (Red) network through a one-way guard. At the Red network, the network information from the Black network may be combined with network information from one or more Red networks. The combined network information may then be used to visualize a cross-domain network topology of both Red and Black networks, and to implement network management functions.
FILED	Friday, October 10, 2014
APPL NO	14/512123
ART UNIT	2451 — Computer Networks
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 41/22 (20130101) H04L 41/28 (20130101) H04L 41/0853 (20130101) H04L 41/0856 (20130101) H04L 63/02 (20130101) Original (OR) Class H04L 63/20 (20130101) H04L 63/0272 (20130101)
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09736183 — Verifying access-control policies with arithmetic quantifier-free form constraints

US 09736183	Narain et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	TT GOVERNMENT SOLUTIONS, INC. (Basking Ridge, New Jersey)
ASSIGNEE(S)	VENCORE LABS, INC. (Basking Ridge, New Jersey)
INVENTOR(S)	Sanjai Narain (Madison, New Jersey); Gary Levin (Bedminster, New Jersey)
ABSTRACT	A system and method is provided for verifying an access-control policy against a particular constraint for a multi-step operation. In disclosed embodiments, the method includes expressing the access-control policy as a first quantifier-free form (QFF) constraint and identifying the particular constraint as a second QFF constraint. The method also includes identifying an operation vector and providing copies of the operation vector associated with steps in the multi-step operation. The method also includes determining a third QFF constraint using the first QFF constraint, the second QFF constraint, and the copies of the operation vector. The method also includes solving the third QFF constraint to determine a solution and outputting a result of the solving.
FILED	Monday, July 28, 2014
APPL NO	14/444475
ART UNIT	2458 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 7/60 (20130101) G06F 11/00 (20130101) G06F 13/00 (20130101) G06F 13/362 (20130101) G06F 17/00 (20130101) G06F 21/62 (20130101) G06F 21/604 (20130101) G06F 21/6209 (20130101) G06F 21/6218 (20130101) G06F 2221/2113 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/06823 (20130101) H04L 63/10 (20130101) H04L 63/20 (20130101) Original (OR) Class
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09736860 — Systems and methods for scheduling of a shared resource

US 09736860	Khoury et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
ASSIGNEE(S)	Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S)	Joud Khoury (Boston, Massachusetts); Christophe Jean-Claude Merlin (Malden, Massachusetts); Dan Alan Coffin (Sudbury, Massachusetts)
ABSTRACT	Generally discussed herein are systems, apparatuses, and methods for scheduling node access to a shared resource. A method can include determining a position assignment for each of a plurality of nodes to create a ring schedule, the ring schedule defining time frames in which each node of the plurality of nodes has access to a resource that is shared among the plurality of nodes, the ring schedule comprising a plurality of epochs, and each of the plurality of epochs comprising a plurality of positions that define a time at which access to the resource begins, each of a plurality of nodes including a position assignment each epoch, and updating the ring schedule including permuting positions of the ring schedule with the position assignment remaining static or changing at least one position assignment in an epoch of the plurality of epochs.
FILED	Thursday, July 30, 2015
APPL NO	14/813545
ART UNIT	2464 — Multiplex and VoIP
CURRENT CPC	Wireless Communication Networks H04W 74/04 (20130101) Original (OR) Class
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Department of Energy (DOE)

09730898 — Reversible, on-demand generation of aqueous two-phase microdroplets

US 09730898	Collier et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
INVENTOR(S)	Charles Patrick Collier (Oak Ridge, Tennessee); Scott Thomas Retterer (Knoxville, Tennessee); Jonathan Barton Boreyko (Knoxville, Tennessee); Prachya Mruetusatorn (Knoxville, Tennessee)
ABSTRACT	The present invention provides methods of on-demand, reversible generation of aqueous two-phase microdroplets core-shell microbeads, microparticle preparations comprising the core-shell microbeads, and drug delivery formulation comprising the microparticle preparations. Because these aqueous microdroplets have volumes comparable to those of cells, they provide an approach to mimicking the dynamic microcompartmentation of biomaterial that naturally occurs within the cytoplasm of cells. Hence, the present methods generate femtoliter aqueous two-phase droplets within a microfluidic oil channel using gated pressure pulses to generate individual, stationary two-phase microdroplets with a well-defined time zero for carrying out controlled and sequential phase transformations over time. Reversible phase transitions between single-phase, two-phase, and core-shell microbead states are obtained via evaporation-induced dehydration and water rehydration.
FILED	Tuesday, August 20, 2013
APPL NO	13/970724
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 9/5073 (20130101) Original (OR) Class A61K 9/5089 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101)
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09731249 — Polymeric molecular sieve membranes for gas separation

US 09731249	Dai et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Sheng Dai (Knoxville, Tennessee); Zhenan Qiao (Oak Ridge, Tennessee); Songhai Chai (Oak Ridge, Tennessee)
ABSTRACT	A porous polymer membrane useful in gas separation, the porous polymer membrane comprising a polymeric structure having crosslinked aromatic groups and a hierarchical porosity in which micropores having a pore size less than 2 nm are present at least in an outer layer of the porous polymer membrane, and macropores having a pore size of over 50 nm are present at least in an inner layer of the porous polymer membrane. Also described are methods for producing the porous polymer membrane in which a non-porous polymer membrane containing aromatic rings is subjected to a Friedel-Crafts crosslinking reaction in which a crosslinking molecule crosslinks the aromatic rings in the presence of a Friedel-Crafts catalyst and organic solvent under sufficiently elevated temperature, as well as methods for using the porous polymer membranes for gas or liquid separation, filtration, or purification.
FILED	Wednesday, March 25, 2015
APPL NO	14/667968
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) B01D 67/0006 (20130101) B01D 69/02 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 71/28 (20130101) B01D 2323/30 (20130101) B01D 2325/022 (20130101)
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09732083 — Tricyclic gyrase inhibitors

US 09732083	Bensen et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Daniel Bensen (Carlsbad, California); Zhiyong Chen (San Diego, California); John Finn (Encinitas, California); Thanh To Lam (San Diego, California); Suk Joong Lee (San Diego, California); Xiaoming Li (San Diego, California); Douglas W. Phillipson (Del Mar, California); Leslie William Tari (San Diego, California); Michael Trzoss (San Diego, California); Junhu Zhang (San Diego, California); Felice C. Lightstone (Fremont, California); Toan B. Nguyen (San Ramon, California); Sergio E. Wong (San Jose, California); Paul Aristoff (Dexter, Michigan); Michael Jung (Los Angeles, California)
ASSIGNEE(S)	MERCK SHARP and DOHME CORP. (New York, New York); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S)	Daniel Bensen (Carlsbad, California); Zhiyong Chen (San Diego, California); John Finn (Encinitas, California); Thanh To Lam (San Diego, California); Suk Joong Lee (San Diego, California); Xiaoming Li (San Diego, California); Douglas W. Phillipson (Del Mar, California); Leslie William Tari (San Diego, California); Michael Trzoss (San Diego, California); Junhu Zhang (San Diego, California); Felice C. Lightstone (Fremont, California); Toan B. Nguyen (San Ramon, California); Sergio E. Wong (San Jose, California); Paul Aristoff (Dexter, Michigan); Michael Jung (Los Angeles, California)
ABSTRACT	Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
FILED	Wednesday, March 14, 2012
APPL NO	13/496188
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 487/14 (20130101)
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09732266 — Low-melting elemental metal or fusible alloy encapsulated polymerization initiator for delayed initiation

US 09732266	Hermes
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Robert E. Hermes (White Rock, New Mexico)
ABSTRACT	An encapsulated composition for polymerization includes an initiator composition for initiating a polymerization reaction, and a capsule prepared from an elemental metal or fusible alloy having a melting temperature from about 20° C. to about 200° C. A fluid for polymerization includes the encapsulated composition and a monomer. When the capsule melts or breaks open, the initiator is released.
FILED	Wednesday, November 18, 2015
APPL NO	14/945188
ART UNIT	1768 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/00 (20130101) C09K 8/12 (20130101) Original (OR) Class C09K 8/40 (20130101)
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09732330 — Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes

US 09732330	Thompson et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	David N. Thompson (Idaho Falls, Idaho); William A. Apel (Jackson, Wyoming); Vicki S. Thompson (Idaho Falls, Idaho); Thomas E. Ward (PA Furnace, Pennsylvania)
ABSTRACT	A genetically modified organism comprising: at least one nucleic acid sequence and/or at least one recombinant nucleic acid isolated from Alicyclobacillus acidocaldarius and encoding a polypeptide involved in at least partially degrading, cleaving, transporting, metabolizing, or removing polysaccharides, cellulose, lignocellulose, hemicellulose, lignin, starch, sugars, sugar oligomers, carbohydrates, complex carbohydrates, chitin, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups; and at least one nucleic acid sequence and/or at least one recombinant nucleic acid encoding a polypeptide involved in fermenting sugar molecules to a product. Additionally, enzymatic and/or proteinaceous extracts may be isolated from one or more genetically modified organisms. The extracts are utilized to convert biomass into a product. Further provided are methods of converting biomass into products comprising: placing the genetically modified organism and/or enzymatic extracts thereof in fluid contact with polysaccharides, cellulose, lignocellulose, hemicellulose, lignin, starch, sugars, sugar oligomers, carbohydrates, complex carbohydrates, chitin, heteroxylans, glycosides, and/or xylan-, glucan-, galactan-, or mannan-decorating groups.
FILED	Friday, March 18, 2016
APPL NO	15/074297
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Original (OR) Class C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/14 (20130101) C12P 7/065 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2201/00 (20130101) Enzymes C12Y 302/01139 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101)
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09732349 — In vivo unnatural amino acid expression in the methylotrophic yeast Pichia pastoris

US 09732349	Young et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Travis Young (San Diego, California); Peter G. Schultz (La Jolla, California)
ABSTRACT	The invention provides orthogonal translation systems for the production of polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris. Methods for producing polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris are also provided.
FILED	Monday, January 27, 2014
APPL NO	14/165199
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48384 (20130101) Peptides C07K 2319/00 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/815 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101)
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09732444 — Method of synthesizing silica nanofibers using sound waves

US 09732444	Sharma et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Jaswinder K. Sharma (Oak Ridge, Tennessee); Panos G. Datskos (Knoxville, Tennessee)
ABSTRACT	A method for synthesizing silica nanofibers using sound waves is provided. The method includes providing a solution of polyvinyl pyrrolidone, adding sodium citrate and ammonium hydroxide to form a first mixture, adding a silica-based compound to the solution to form a second mixture, and sonicating the second mixture to synthesize a plurality of silica nanofibers having an average cross-sectional diameter of less than 70 nm and having a length on the order of at least several hundred microns. The method can be performed without heating or electrospinning, and instead includes less energy intensive strategies that can be scaled up to an industrial scale. The resulting nanofibers can achieve a decreased mean diameter over conventional fibers. The decreased diameter generally increases the tensile strength of the silica nanofibers, as defects and contaminations decrease with the decreasing diameter.
FILED	Thursday, August 06, 2015
APPL NO	14/819749
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/10 (20130101) B01J 2219/08 (20130101) B01J 2219/0877 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/12 (20130101) C01B 33/023 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/10 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/298 (20150115)
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09732445 — Low temperature stabilization process for production of carbon fiber having structural order

US 09732445	Rios et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Orlando Rios (Knoxville, Tennessee); Michael Alan McGuire (Knoxville, Tennessee); Karren Leslie More (Knoxville, Tennessee); Wyatt Evan Tenhaeff (Rochester, New York); Paul A. Menchhofer (Clinton, Tennessee); Felix Leonard Paulauskas (Knoxville, Tennessee)
ABSTRACT	A method for producing a carbon fiber, the method comprising: (i) subjecting a continuous carbon fiber precursor having a polymeric matrix in which strength-enhancing particles are incorporated to a stabilization process during which the carbon fiber precursor is heated to within a temperature range ranging from the glass transition temperature to no less than 20° C. below the glass transition temperature of the polymeric matrix, wherein the maximum temperature employed in the stabilization process is below 400° C., for a processing time within said temperature range of at least 1 hour in the presence of oxygen and in the presence of a magnetic field of at least 1 Tesla, while said carbon fiber precursor is held under an applied axial tension; and (ii) subjecting the stabilized carbon fiber precursor, following step (i), to a carbonization process. The stabilized carbon fiber precursor, resulting carbon fiber, and articles made thereof are also described.
FILED	Friday, March 06, 2015
APPL NO	14/640788
ART UNIT	1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 44/464 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) D01F 9/12 (20130101) D01F 9/14 (20130101) Original (OR) Class D01F 9/15 (20130101) D01F 9/16 (20130101) D01F 9/17 (20130101) D01F 9/20 (20130101) D01F 9/21 (20130101) D01F 9/22 (20130101) D01F 9/145 (20130101) D01F 9/155 (20130101) D01F 9/225 (20130101)
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09732561 — Method and apparatus for increasing well productivity

US 09732561	Carter, Jr.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Ernest E. Carter, Jr. (Sugar Land, Texas)
ASSIGNEE(S)	Ernest E. Carter, Jr. (Sugar Land, Texas)
INVENTOR(S)	Ernest E. Carter, Jr. (Sugar Land, Texas)
ABSTRACT	This patent application discloses method and apparatus to cut an extended slot connecting a well to a substantial cross section of a desired producing formation whereby material can flow freely between the formation and the wellbore and at least partially overcome the flow limitations of low permeability formations without the environmental issues associated with hydraulic fracturing. It is further disclosed that the connection between said slot and the formation may be further enhanced by explosive or combustive processes that rapidly generate gas pressure within the large surface area of the slot, thereby changing its characteristics and forcing open additional fractures into the cross section of formation exposed to the slot. The method may significantly increase the recoverable percentage or natural gas from low permeability deposits such as shale and coal.
FILED	Thursday, June 30, 2016
APPL NO	15/198995
ART UNIT	3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 7/04 (20130101) E21B 7/28 (20130101) Original (OR) Class E21B 11/00 (20130101) E21B 11/06 (20130101) E21B 43/04 (20130101) E21B 43/26 (20130101) E21B 43/263 (20130101) E21B 43/305 (20130101)
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09732621 — Air riding seal with purge cavity

US 09732621	Sexton et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Thomas D Sexton (Tequesta, Florida); Jacob A Mills (Jupiter, Florida)
ASSIGNEE(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S)	Thomas D Sexton (Tequesta, Florida); Jacob A Mills (Jupiter, Florida)
ABSTRACT	An air riding seal for a turbine in a gas turbine engine, where an annular piston is axial moveable within an annular piston chamber formed in a stator of the turbine and forms a seal with a surface on the rotor using pressurized air that forms a cushion in a pocket of the annular piston. A purge cavity is formed on the annular piston and is connected to a purge hole that extends through the annular piston to a lower pressure region around the annular piston or through the rotor to an opposite side. The annular piston is sealed also with inner and outer seals that can be a labyrinth seal to form an additional seal than the cushion of air in the pocket to prevent the face of the air riding seal from overheating.
FILED	Thursday, November 20, 2014
APPL NO	14/548492
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/10 (20130101) F01D 11/025 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101)
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09732622 — Self-balancing air riding seal for a turbine

US 09732622	Mills
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Jacob A Mills (Jupiter, Florida)
ASSIGNEE(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S)	Jacob A Mills (Jupiter, Florida)
ABSTRACT	A turbine of a gas turbine engine has an air riding seal that forms a seal between a rotor and a stator of the turbine, the air riding seal including an annular piston movable in an axial direction under the influence of a pressure on one side with a pressure acting on an opposite side that self-balances the air riding seal during the steady state condition of the engine and lifts off the seal during engine transients.
FILED	Tuesday, June 16, 2015
APPL NO	14/740317
ART UNIT	3753 — Fluid Handling and Dispensing
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/02 (20130101) F01D 11/025 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/55 (20130101) Pistons; Cylinders; Sealings F16J 15/342 (20130101) F16J 15/346 (20130101) F16J 15/3448 (20130101)
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09733171 — Acoustic concentration of particles in fluid flow

US 09733171	Ward et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS)
APPLICANT(S)	Michael W. Ward (Los Alamos, New Mexico); Gregory Kaduchak (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Michael W. Ward (Los Alamos, New Mexico); Gregory Kaduchak (Los Alamos, New Mexico)
ABSTRACT	Disclosed herein is a acoustic concentration of particles in a fluid flow that includes a substantially acoustically transparent membrane and a vibration generator that define a fluid flow path therebetween. The fluid flow path is in fluid communication with a fluid source and a fluid outlet and the vibration generator is disposed adjacent the fluid flow path and is capable of producing an acoustic field in the fluid flow path. The acoustic field produces at least one pressure minima in the fluid flow path at a predetermined location within the fluid flow path and forces predetermined particles in the fluid flow path to the at least one pressure minima.
FILED	Tuesday, October 12, 2010
APPL NO	12/903042
ART UNIT	3653 — Printing/Measuring and Testing
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 47/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) Original (OR) Class G01N 2001/4094 (20130101)
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09733228 — Methods of analyzing crude oil

US 09733228	Cooks et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert Graham Cooks (West Lafayette, Indiana); Fred Paul Mark Jjunju (West Lafayette, Indiana); Anyin Li (West Lafayette, Indiana); Iman S. Rogan (Thuwal, Saudi Arabia)
ABSTRACT	The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps.
FILED	Thursday, January 23, 2014
APPL NO	14/426879
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/724 (20130101) G01N 30/7266 (20130101) G01N 33/2823 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/10 (20130101) H01J 49/0031 (20130101) H01J 49/164 (20130101)
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09733287 — Distributed control system for parallel-connected DC boost converters

US 09733287	Goldsmith
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Steven Goldsmith (Minneapolis, Minnesota)
ASSIGNEE(S)	MICHIGAN TECHNOLOGICAL UNIVERSITY (Houghton, Michigan)
INVENTOR(S)	Steven Goldsmith (Minneapolis, Minnesota)
ABSTRACT	The disclosed invention is a distributed control system for operating a DC bus fed by disparate DC power sources that service a known or unknown load. The voltage sources vary in v-i characteristics and have time-varying, maximum supply capacities. Each source is connected to the bus via a boost converter, which may have different dynamic characteristics and power transfer capacities, but are controlled through PWM. The invention tracks the time-varying power sources and apportions their power contribution while maintaining the DC bus voltage within the specifications. A central digital controller solves the steady-state system for the optimal duty cycle settings that achieve a desired power supply apportionment scheme for a known or predictable DC load. A distributed networked control system is derived from the central system that utilizes communications among controllers to compute a shared estimate of the unknown time-varying load through shared bus current measurements and bus voltage measurements.
FILED	Monday, March 17, 2014
APPL NO	14/215373
ART UNIT	2864 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 21/133 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/10 (20130101)
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09733367 — Neutron detection apparatus and method

US 09733367	Derzon et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and EngineeringSolutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Mark S. Derzon (Albuquerque, New Mexico); Theodore T. Borek, III (Albuquerque, New Mexico)
ABSTRACT	An apparatus for neutron detection is provided. The apparatus comprises a sensor medium in electrical contact with an electrode arrangement conformed to collect radiation-generated charge from the sensor medium. The sensor medium comprises a borazine and/or a borazine-based polymer.
FILED	Friday, February 28, 2014
APPL NO	14/193688
ART UNIT	2884 — Optics
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Measurement of Nuclear or X-radiation G01T 3/00 (20130101) Original (OR) Class
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09733625 — Trip optimization system and method for a train

US 09733625	Kumar et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Ajith Kuttannair Kumar (Erie, Pennsylvania); Glenn Robert Shaffer (Erie, Pennsylvania); Paul Kenneth Houpt (Schenectady, New York); Bernardo Adrian Movsichoff (Clifton Park, New York); David So Keung Chan (Niskayuna, New York); Sukru Alper Eker (Danbury, Connecticut)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Ajith Kuttannair Kumar (Erie, Pennsylvania); Glenn Robert Shaffer (Erie, Pennsylvania); Paul Kenneth Houpt (Schenectady, New York); Bernardo Adrian Movsichoff (Clifton Park, New York); David So Keung Chan (Niskayuna, New York); Sukru Alper Eker (Danbury, Connecticut)
ABSTRACT	A system for operating a train having one or more locomotive consists with each locomotive consist comprising one or more locomotives, the system including a locator element to determine a location of the train, a track characterization element to provide information about a track, a sensor for measuring an operating condition of the locomotive consist, a processor operable to receive information from the locator element, the track characterizing element, and the sensor, and an algorithm embodied within the processor having access to the information to create a trip plan that optimizes performance of the locomotive consist in accordance with one or more operational criteria for the train.
FILED	Monday, March 20, 2006
APPL NO	11/385354
ART UNIT	3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 3/006 (20130101) B61L 25/025 (20130101) B61L 25/026 (20130101) B61L 27/0027 (20130101) B61L 2205/04 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/021 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06 (20130101) G06Q 10/063 (20130101)
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09733831 — Generation-based memory synchronization in a multiprocessor system with weakly consistent memory accesses

US 09733831	Ohmacht
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	GLOBALFOUNDRIES INC. (Grand Cayman, Cayman Islands)
ASSIGNEE(S)	GLOBALFOUNDRIES INC. (Grand Cayman, Cayman Islands)
INVENTOR(S)	Martin Ohmacht (Yorktown Heights, New York)
ABSTRACT	In a multiprocessor system, a central memory synchronization module coordinates memory synchronization requests responsive to memory access requests in flight, a generation counter, and a reclaim pointer. The central module communicates via point-to-point communication. The module includes a global OR reduce tree for each memory access requesting device, for detecting memory access requests in flight. An interface unit is implemented associated with each processor requesting synchronization. The interface unit includes multiple generation completion detectors. The generation count and reclaim pointer do not pass one another.
FILED	Tuesday, July 01, 2014
APPL NO	14/320841
ART UNIT	2132 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 3/0604 (20130101) Original (OR) Class G06F 3/0655 (20130101) G06F 3/0671 (20130101) G06F 9/522 (20130101) G06F 9/3004 (20130101) G06F 9/3834 (20130101) G06F 9/30047 (20130101) G06F 9/30087 (20130101) G06F 13/1689 (20130101) G06F 2003/0697 (20130101) Static Stores G11C 7/22 (20130101)
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09735008 — Use of surfactants to control island size and density

US 09735008	Merrell et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Jason Merrell (Draper, Utah); Feng Liu (Salt Lake City, Utah); Gerald B. Stringfellow (Salt Lake City, Utah)
ABSTRACT	Methods of controlling island size and density on an OMVPE growth film may comprise adding a surfactant at a critical concentration level, allowing a growth phase for a first period of time, and ending the growth phase when desired island size and density are achieved. For example, the island size and density of an OMVPE grown InGaN thin film may be controlled by adding an antimony surfactant at a critical concentration level.
FILED	Friday, October 25, 2013
APPL NO	14/063143
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/02 (20130101) C30B 29/403 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/0257 (20130101) H01L 21/0259 (20130101) H01L 21/0262 (20130101) Original (OR) Class H01L 21/02389 (20130101) H01L 21/02398 (20130101) H01L 21/02458 (20130101)
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09735306 — Wüstite-based photoelectrodes with lithium, hydrogen, sodium, magnesium, manganese, zinc and nickel additives

US 09735306	Carter et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Emily Ann Carter (Belle Mead, New Jersey); Maytal Caspary Toroker (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); TECHNION RESEARCH and DEVELOPMENT FOUNDATION, LTD (Haifa, Israel)
INVENTOR(S)	Emily Ann Carter (Belle Mead, New Jersey); Maytal Caspary Toroker (Princeton, New Jersey)
ABSTRACT	A photoelectrode, photovoltaic device and photoelectrochemical cell and methods of making are disclosed. The photoelectrode includes an electrode at least partially formed of FeO combined with at least one of lithium, hydrogen, sodium, magnesium, manganese, zinc, and nickel. The electrode may be doped with at least one of lithium, hydrogen, and sodium. The electrode may be alloyed with at least one of magnesium, manganese, zinc, and nickel.
FILED	Tuesday, May 21, 2013
APPL NO	13/899049
ART UNIT	1757 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/07 (20130101) H01L 31/18 (20130101) Original (OR) Class H01L 31/032 (20130101) H01L 31/072 (20130101) H01L 31/0264 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101)
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09735318 — Epitaxial hexagonal materials on IBAD-textured substrates

US 09735318	Matias et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	iBeam Materials, Inc. (Santa Fe, New Mexico)
ASSIGNEE(S)	iBeam Materials, Inc. (Santa Fe, New Mexico)
INVENTOR(S)	Vladimir Matias (Santa Fe, New Mexico); Christopher Yung (Santa Fe, New Mexico)
ABSTRACT	A multilayer structure including a hexagonal epitaxial layer, such as GaN or other group III-nitride (III-N) semiconductors, a <111> oriented textured layer, and a non-single crystal substrate, and methods for making the same. The textured layer has a crystalline alignment preferably formed by the ion-beam assisted deposition (IBAD) texturing process and can be biaxially aligned. The in-plane crystalline texture of the textured layer is sufficiently low to allow growth of high quality hexagonal material, but can still be significantly greater than the required in-plane crystalline texture of the hexagonal material. The IBAD process enables low-cost, large-area, flexible metal foil substrates to be used as potential alternatives to single-crystal sapphire and silicon for manufacture of electronic devices, enabling scaled-up roll-to-roll, sheet-to-sheet, or similar fabrication processes to be used. The user is able to choose a substrate for its mechanical and thermal properties, such as how well its coefficient of thermal expansion matches that of the hexagonal epitaxial layer, while choosing a textured layer that more closely lattice matches that layer.
FILED	Wednesday, February 10, 2016
APPL NO	15/041017
ART UNIT	2896 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02458 (20130101) H01L 21/02483 (20130101) H01L 21/02488 (20130101) H01L 21/02502 (20130101) H01L 21/02516 (20130101) H01L 27/15 (20130101) H01L 27/32 (20130101) H01L 33/02 (20130101) H01L 33/16 (20130101) H01L 33/32 (20130101) Original (OR) Class
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09735411 — Polymer for use as protective layers and other components in electrochemical cells

US 09735411	Viner et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Sion Power Corporation (Tucson, Arizona); BASF SE (Ludwigshafen, Germany)
ASSIGNEE(S)	Sion Power Corporation (Tucson, Arizona); BASF SE (Ludwigshafen, Germany)
INVENTOR(S)	Veronika G. Viner (Tucson, Arizona); Sven Fleischmann (Ludwigshafen, Germany)
ABSTRACT	Polymers for use as protective layers and other components in electrochemical cells are provided. In some embodiments, the electrochemical cell is a lithium-based electrochemical cell.
FILED	Wednesday, May 27, 2015
APPL NO	14/723132
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/145 (20130101) H01M 2/1653 (20130101) H01M 2/1673 (20130101) Original (OR) Class H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 2300/0085 (20130101)
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09735444 — Hard carbon composite for alkali metal-ion batteries

US 09735444	Ji et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Oregon State University (Corvallis, Oregon); Sharp Laboratories of America, Inc. (Camas, Washington)
ASSIGNEE(S)	Oregon State University (Corvallis, Oregon); Sharp Laboratories of America (Camas, Washington)
INVENTOR(S)	Xiulei Ji (Corvallis, Oregon); Wei Luo (Corvallis, Oregon); Clement Bommier (Corvallis, Oregon); Yuhao Lu (Vancouver, Washington); Sean Vail (Vancouver, Washington); Jong-Jan Lee (Camas, Washington)
ABSTRACT	A method is provided for fabricating a graphene-doped, carbohydrate-derived hard carbon (G-HC) composite material for alkali metal-ion batteries. The method provides graphene oxide (GO) dispersed in an aqueous solution. A carbohydrate is dissolved into the aqueous solution and subsequently the water is removed to create a precipitate. In one aspect, the carbohydrate is sucrose. The precipitate is dehydrated and exposed to a thermal treatment of less than 1200 degrees C. to carbonize the carbohydrate. The result is the formation of a graphene-doped, carbohydrate-derived hard carbon (G-HC) composite. Typically, the G-HC composite is made up of graphene in the range of 0.1 and 20% by weight (wt %), and HC in the range of 80 to 99.9 wt %. The G-HC composite has a specific surface area of less than 10 square meters per gram (m²/g). A G-HC composite suitable for use in alkali metal-ion batteries electrodes is also provided.
FILED	Friday, June 05, 2015
APPL NO	14/731667
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 31/0476 (20130101) C01B 31/0484 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/364 (20130101) H01M 4/587 (20130101) H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49108 (20150115)
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National Science Foundation (NSF)

09731052 — Methods for stepwise deposition of silk fibroin coatings

US 09731052	Kaplan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Xianyan Wang (Acton, Massachusetts)
ABSTRACT	The invention provides a method for the controlled assembly of layered silk fibroin coatings using aqueous silk fibroin material. The methods described herein can be used to coat substrates of any material, shape, or size. Importantly, the described methods enable control of the biomaterial surface chemistry, thickness, morphology and structure using layered thin film coatings, or bulk coatings. Furthermore, the methods can be performed in all water and do not require intensive chemical processing enabling controlled entrapment of labile molecules such as, drugs, cytokines, and even cells or viruses to generate functional coatings that can be used in a variety of applications.
FILED	Wednesday, May 06, 2015
APPL NO	14/705509
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/32 (20130101) A61L 15/44 (20130101) A61L 27/50 (20130101) A61L 27/3604 (20130101) A61L 31/10 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 2300/43 (20130101) A61L 2300/416 (20130101) A61L 2400/12 (20130101) A61L 2400/18 (20130101)
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09731422 — Methods, apparatuses, and systems for micromanipulation with adhesive fibrillar structures

US 09731422	Sitti et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University, a Pennsylvania Non-Profit Corporation (Pittsburgh, Pennsylvania)
INVENTOR(S)	Metin Sitti (Pittsburgh, Pennsylvania); Yi{hacek over (g)}it Mengüç (Somerville, Massachusetts)
ABSTRACT	The present invention are methods for fabrication of micro- and/or nano-scale adhesive fibers and their use for movement and manipulation of objects. Further disclosed is a method of manipulating a part by providing a manipulation device with a plurality of fibers, where each fiber has a tip with a flat surface that is parallel to a backing layer, contacting the flat surfaces on an object, moving the object to a new location, then disengaging the tips from the object.
FILED	Friday, December 21, 2012
APPL NO	14/368079
ART UNIT	3652 — Material and Article Handling
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 7/00 (20130101) B25J 15/008 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/026 (20130101) B29C 39/26 (20130101) B29C 39/36 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/10 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/756 (20130101) B29L 2031/7562 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2913 (20150115)
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09731614 — Mobile wireless power transfer

US 09731614	Sarwat et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Arif Sarwat (Davie, Florida); Shekhar Bhansali (Weston, Florida); Kang Yen (Miami, Florida); Masood Moghaddami (Miami, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Arif Sarwat (Davie, Florida); Shekhar Bhansali (Weston, Florida); Kang Yen (Miami, Florida); Masood Moghaddami (Miami, Florida)
ABSTRACT	Mobile power transfer methods and apparatuses for charging electric vehicles both statically and dynamically are provided. A mobile electric charging station can include a chassis, a power source connected to the chassis, a power control system connected to the chassis and the power source, and a wireless power transmitter deployment structure connected to the chassis and the power control system. The power source can be one more of an electric grid connection, a battery, a generator, and solar panels.
FILED	Thursday, September 29, 2016
APPL NO	15/279801
ART UNIT	2859 — Printing/Measuring and Testing
CURRENT CPC	Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/182 (20130101) B60L 11/1824 (20130101) B60L 11/1829 (20130101) Original (OR) Class B60L 2230/22 (20130101) B60L 2230/30 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101)
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09731983 — Ion exchange methods for treating water hardness

US 09731983	Sengupta et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	LEHIGH UNIVERSITY (Bethlehem, Pennsylvania)
ASSIGNEE(S)	Lehigh University (Bethlehem, Pennsylvania)
INVENTOR(S)	Arup K Sengupta (Bethlehem, Pennsylvania); Surapol Padungthon (Bethlehem, Pennsylvania); Michael German (Nottingham, Maryland); Jinze Li (Bethlehem, Pennsylvania)
ABSTRACT	The present invention includes a novel salt-free water softening method that utilizes an exchange medium (such as a gel exchange polymer, a macroporous exchange polymer, or an inorganic cation exchanger) that is pre-loaded with a polyvalent cation that has low solubility in aqueous phase at nearly neutral pH. The method of the invention does not require use of a sodium salt or mineral acid in the regeneration of the exchange medium.
FILED	Friday, October 04, 2013
APPL NO	14/431158
ART UNIT	1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/05 (20170101) B01J 39/09 (20170101) B01J 39/20 (20130101) B01J 49/06 (20170101) B01J 49/53 (20170101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) Original (OR) Class C02F 2001/425 (20130101) C02F 2101/14 (20130101) C02F 2101/30 (20130101) C02F 2101/105 (20130101) C02F 2103/08 (20130101) C02F 2303/16 (20130101)
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09732235 — Corrosion resistant hybrid silanized epoxy ester resins, coatings and surface pre-treatment formulations

US 09732235	Iroh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	University of Cincinnati (Cincinnati, Ohio)
ASSIGNEE(S)	University Of Cincinnati (Cincinnati, Ohio)
INVENTOR(S)	Jude Iroh (Mason, Ohio); Jaspreet S. Beemat (Maricopa, Arizona)
ABSTRACT	A self-healing coating composition for use on metals includes a polyurea, an epoxy ester unsaturated resin, a combination of amine terminated siloxane and epoxy terminated siloxane and an organoclay. The polyurea is a water-soluble, aromatic polyurea and likewise, the epoxy ester is a water-soluble, aromatic epoxy ester. The coating composition is formed in a non-volatile solvent, such as N-Methylpyrrolidone. It can be applied to a metal surface and cured at room temperature to form a coating that is resistant to corrosion. Further the coating self-heals in a manner similar to a chromate coating.
FILED	Tuesday, June 09, 2015
APPL NO	14/734089
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/3243 (20130101) C08G 18/7671 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/346 (20130101) C08K 3/346 (20130101) C08K 3/346 (20130101) Compositions of Macromolecular Compounds C08L 63/10 (20130101) C08L 75/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/08 (20130101) Original (OR) Class C09D 163/10 (20130101) C09D 163/10 (20130101) C09D 175/02 (20130101) C09D 175/04 (20130101) C09D 175/04 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 11/10 (20130101)
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09732273 — Quantum dots, rods, wires, sheets, and ribbons, and uses thereof

US 09732273	Yan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)	Hao Yan (Chandler, Arizona); Zhengtao Deng (Tempe, Arizona); Yan Liu (Chandler, Arizona)
ASSIGNEE(S)	Arizona Board of Regents (Scottsdale, Arizona)
INVENTOR(S)	Hao Yan (Chandler, Arizona); Zhengtao Deng (Tempe, Arizona); Yan Liu (Chandler, Arizona)
ABSTRACT	Described are Zn_xCd_1-xS_ySe_1-y/ZnS_zSe_1-zcore/shell nanocrystals, CdTe/CdS/ZnS core/shell/shell nanocrystals, optionally doped Zn(S,Se,Te) nano- and quantum wires, and SnS quantum sheets or ribbons, methods for making the same, and their use in biomedical and photonic applications, such as sensors for analytes in cells and preparation of field effect transistors.
FILED	Thursday, October 29, 2015
APPL NO	14/926733
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 10/00 (20130101) B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) C01B 19/007 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 9/08 (20130101) C01G 19/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/04 (20130101) C01P 2004/16 (20130101) C01P 2004/17 (20130101) C01P 2004/64 (20130101) C01P 2004/86 (20130101) C01P 2004/88 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/08 (20130101) C09K 11/54 (20130101) C09K 11/565 (20130101) C09K 11/574 (20130101) C09K 11/661 (20130101) C09K 11/0811 (20130101) C09K 11/883 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/22 (20130101) H01L 29/122 (20130101) H01L 29/127 (20130101) H01L 29/0669 (20130101) H01L 29/775 (20130101) H01L 29/66977 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/294 (20150115) Y10T 428/12431 (20150115)
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09732277 — Field induced and controlled heliconical structure of cholesteric liquid crystal

US 09732277	Lavrentovich et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Kent State University (Kent, Ohio)
ASSIGNEE(S)	KENT STATE UNIVERSITY (Kent, Ohio); THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (Aberdeen, United Kingdom)
INVENTOR(S)	Oleg D. Lavrentovich (Kent, Ohio); Jie V. Xiang (Kent, Ohio); Sergij V. Shiyanovskii (Stow, Ohio); Corrie T. Imrie (Aberdeen, United Kingdom); Daniel A. Paterson (Aberdeen, United Kingdom); John M. Storey (Aberdeen, United Kingdom)
ABSTRACT	A liquid crystal cell includes substrates defining a gap and electrodes having one of (i) an in-plane geometry generating an electric field parallel with the substrates and (ii) a top-down geometry generating an electric field across the gap between the two spaced apart substrates. A liquid crystal material disposed in the gap between the substrates comprises a chiral nematic material formed by a mixture of: 1-(4-cyanobiphenyl-4′-yl)-6-(4-cyanobiphenyl-4′-yloxy)hexane (CB6OCB) or α,ω-bis(4,4-cyanobiphenyl)nonane (CB9CB) dimeric liquid crystal material; at least one additional dimeric liquid crystal material; and a chiral dopant. The liquid crystal material within an operational range of electric field applied by the electrodes exhibits a heliconical state with an oblique angle helicoid director whose helicoid axis is oriented parallel with the electric field and whose helicoid pitch is sized to provide diffraction or Bragg reflection of light in a spectral range of interest impinging on one of the substrates of the liquid crystal cell.
FILED	Thursday, February 25, 2016
APPL NO	15/053643
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/14 (20130101) C09K 19/586 (20130101) Original (OR) Class C09K 2019/0444 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/13718 (20130101) G02F 1/134363 (20130101)
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09732316 — Devices and methods for pharmacokinetic-based cell culture system

US 09732316	Shuler et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S)	Michael Shuler (Ithaca, New York); Gregory T. Baxter (Salinas, California); Aaron Sin (Ithaca, New York); Robert Andrew Harrison (Toronto, Canada); Scott Meyers (Norristown, Pennsylvania)
ABSTRACT	A cell culture device comprising a microscale chamber dimensioned to maintain a cell under conditions that give rise to a value for at least one pharmacokinetic parameter in vitro that is comparable to a value for the same at least one pharmacokinetic parameter obtained with respect to the same type of cell in vivo, wherein the microscale chamber is configured for flow of culture medium, and wherein the at least one pharmacokinetic parameter is selected from tissue size ratio, tissue to blood volume ratio, drug residence time, flow rate, circulatory transit time, liquid residence time, and liquid to cell ratio.
FILED	Friday, February 26, 2016
APPL NO	15/055385
ART UNIT	1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 23/44 (20130101) C12M 41/46 (20130101) Original (OR) Class C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0671 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/5067 (20130101)
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09732352 — Mutations in Solanaceae plants that modulate shoot architecture and enhance yield-related phenotypes

US 09732352	Lippman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS)
APPLICANT(S)	Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
ASSIGNEE(S)	Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
INVENTOR(S)	Zachary Lippman (North Bellmore, New York); Soon-Ju Park (Cold Spring Harbor, New York)
ABSTRACT	Provided herein are genetically-altered Solanaceae plants, compositions related to the Solanaceae plants, and methods of making the Solanaceae plants.
FILED	Wednesday, March 13, 2013
APPL NO	13/799831
ART UNIT	1662 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) A01H 5/08 (20130101) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/827 (20130101) Original (OR) Class C12N 15/8261 (20130101)
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09732365 — Biosynthesis of paclitaxel intermediate

US 09732365	Walker
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	Kevin Walker (Holt, Michigan)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Kevin Walker (Holt, Michigan)
ABSTRACT	The invention relates to methods of making compounds useful for production of paclitaxel and analogs or derivatives thereof.
FILED	Monday, June 18, 2012
APPL NO	14/408515
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/90 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/02 (20130101) Original (OR) Class Enzymes C12Y 501/01011 (20130101)
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09732377 — Microfluidic systems and methods for chromatin immunoprecipitation (ChIP)

US 09732377	Lu et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Chang Lu (Blacksburg, Virginia); Zhenning Cao (Blacksburg, Virginia)
ASSIGNEE(S)	Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
INVENTOR(S)	Chang Lu (Blacksburg, Virginia); Zhenning Cao (Blacksburg, Virginia)
ABSTRACT	An integrated microfluidic chromatin immunoprecipitation assay dramatically improves the collection efficiency of ChIP DNA from cells. Immunoprecipitation of chromatin fragments is conducted in a microfluidic chamber with a large fraction of its volume (e.g., ˜15-40%) occupied by magnetic immunoprecipitation (IP) beads. Oscillating washing of the beads, enabled by, e.g., solenoid valves (controlled by a computer) and high pressure attached to both ends of the microfluidic chamber, effectively removes unbound chromatin and produces high-quality ChIP DNA. ChIP DNA produced by an example device generates excellent results in the subsequent DNA library preparation. The ChIP-seq (i.e., ChIP followed by next-generation sequencing) results match very well with public data generated using much larger cell sample sizes and a conventional approach.
FILED	Friday, October 10, 2014
APPL NO	14/511422
ART UNIT	1677 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0668 (20130101) B01L 2300/0816 (20130101) B01L 2300/0877 (20130101) B01L 2400/043 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 2522/10 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101) G01N 33/54326 (20130101)
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09733091 — Collaborative creation of indoor maps

US 09733091	Kordari et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	TRX Systems, Inc. (Greenbelt, Maryland)
ASSIGNEE(S)	TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S)	Kamiar Kordari (McLean, Virginia); Benjamin Funk (Hanover, Maryland); Carole Teolis (Glenn Dale, Maryland); Jared Napora (Severn, Maryland); John Karvounis (Bowie, Maryland); Dan Hakim (Silver Spring, Maryland); Christopher Giles (Prince Frederick, Maryland); Carol Politi (Bethesda, Maryland)
ABSTRACT	This disclosure provides techniques for the creation of maps of indoor spaces. In these techniques, an individual or a team with no mapping or cartography expertise can contribute to the creation of maps of buildings, campuses or cities. An indoor location system can track the location of contributors in the building. As they walk through indoor spaces, an application may automatically create a map based on data from motion sensors by both tracking the location of the contributors and also inferring building features such as hallways, stairways, and elevators based on the tracked contributors' motions as they move through a structure. With these techniques, the process of mapping buildings can be crowd sourced to a large number of contributors, making the indoor mapping process efficient and easy to scale up.
FILED	Wednesday, February 12, 2014
APPL NO	14/178605
ART UNIT	3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/206 (20130101) Original (OR) Class
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09733125 — Resonator enhanced raman spectroscopy

US 09733125	Liu et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC) National Institute for Occupational Safety and Health (NIOSH) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	The Penn State Research Foundation (University Park, Pennsylvania); Washington University (St. Louis, Missouri)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania); Washington University (St. Louis, Missouri)
INVENTOR(S)	Zhiwen Liu (State College, Pennsylvania); Lan Yang (Saint Louis, Missouri); Perry Edwards (State College, Pennsylvania); Corey Janisch (University Park, Pennsylvania); Bo Peng (Saint Louis, Missouri); Sahin Ozdemir (University City, Missouri)
ABSTRACT	Embodiments of the invention provide Raman spectroscopy methods and devices that exploit high quality factor (Q) resonators to enhance Raman signal by several orders of magnitude over the signal typically expected for Raman methods. Embodiments typically include one or more resonators, typically microtoroid microresonators. Embodiments also take advantage of Rayleigh scattering using these microresonators. Embodiments may be particularly useful for non-labeled nanoparticle sensing.
FILED	Wednesday, September 25, 2013
APPL NO	14/431080
ART UNIT	2877 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/26 (20130101) G01J 3/44 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 3/0224 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101)
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09733545 — Nonlinear metasurfaces based on plasmonic resonators coupled to intersubband transitions

US 09733545	Belkin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Mikhail Belkin (Austin, Texas); Andrea Alu (Austin, Texas); Jongwon Lee (Austin, Texas); Mykhailo Tymchenko (Austin, Texas)
ABSTRACT	A nonlinear metasurface structure including a multi-quantum-well layer designed for a nonlinear response for a desired nonlinear optical process and an array of nanoantennas coupled to the intersubband transitions of the multi-quantum-well layer. Each nanoantenna in the array is designed to have electromagnetic resonances at or close to all input and output frequencies of a given nonlinear optical process. Nanoantennas allow efficient coupling of any incident and outgoing light polarizations to intersubband transitions. Nanoantennas may further provide significant field enhancement in the multi-quantum-well layer. As a result, the nonlinear metasurface structure can be designed to produce a highly nonlinear response for any polarization and angle of incidence of incoming and outgoing waves in a nonlinear optical process. Due to their very larger nonlinear response, efficient frequency conversion can be produced in these metasurfaces without the stringent phase-matching constraints of bulk nonlinear crystals.
FILED	Thursday, July 30, 2015
APPL NO	14/814176
ART UNIT	2872 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/017 (20130101) G02F 1/3501 (20130101) G02F 1/3556 (20130101) Original (OR) Class G02F 2001/01775 (20130101) G02F 2001/3505 (20130101) G02F 2001/3507 (20130101) G02F 2202/30 (20130101) G02F 2202/108 (20130101) G02F 2203/10 (20130101)
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09733746 — Touch interface device having an electrostatic multitouch surface and method for controlling the device

US 09733746	Colgate et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	J. Edward Colgate (Evanston, Illinois); Michael A. Peshkin (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	J. Edward Colgate (Evanston, Illinois); Michael A. Peshkin (Evanston, Illinois)
ABSTRACT	A touch interface device includes a touch surface, a first electrode, and a second electrode. The first electrode is coupled with the touch surface. The first electrode also configured to receive a first haptic actuation electric potential. The second electrode is coupled with the touch surface. The second electrode also is configured to receive a different, second haptic actuation electric potential having an opposite polarity than the first haptic actuation potential. The first and second electrodes generate an electrostatic force that is imparted on one or more appendages of an operator that touches the touch surface above both the first electrode and the second electrode in order to generate a haptic effect.
FILED	Thursday, May 10, 2012
APPL NO	13/468818
ART UNIT	2693 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/016 (20130101) G06F 3/041 (20130101) G06F 3/044 (20130101) G06F 3/045 (20130101) G06F 3/046 (20130101) G06F 3/0412 (20130101) G06F 3/0414 (20130101) Original (OR) Class G06F 3/0416 (20130101) G06F 2203/04101 (20130101) G06F 2203/04105 (20130101) G06F 2203/04112 (20130101) G06F 2203/04113 (20130101)
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09734161 — Streaming representation of moving objects and shapes in a geographic information service

US 09734161	Rishe
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Human Resource Development (HRD)
APPLICANT(S)	Naphtali David Rishe (Miami Beach, Florida)
ASSIGNEE(S)	The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S)	Naphtali David Rishe (Miami Beach, Florida)
ABSTRACT	A geographical information system (GIS) is described that enables querying, analysis and visualization of real-time streaming data pertaining to at least one moving object or entity (e.g., vehicles, people, sensors, weather phenomena, etc.) in conjunction with relatively static multi-temporal geospatial data. An application programming interface is provided to present the GIS functionality for handling dynamically moving objects or entities to clients.
FILED	Monday, March 17, 2014
APPL NO	14/215484
ART UNIT	2162 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 3/0481 (20130101) G06F 17/30241 (20130101) Original (OR) Class
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09734601 — Highly accelerated imaging and image reconstruction using adaptive sparsifying transforms

US 09734601	Bresler et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Yoram Bresler (Urbana, Illinois); Luke A. Pfister (Urbana, Illinois); Saiprasad Ravishankar (Urbana, Illinois)
ABSTRACT	A system executes efficient computational methods for high quality image reconstructions from a relatively small number of noisy (or degraded) sensor imaging measurements or scans. The system includes a processing device and instructions. The processing device executes the instructions to employ transform learning as a regularizer for solving inverse problems when reconstructing an image from the imaging measurements, the instructions executable to: adapt a transform model to a first set of image patches of a first set of images containing at least a first image, to model the first set of image patches as sparse in a transform domain while allowing deviation from perfect sparsity; reconstruct a second image by minimizing an optimization objective comprising a transform-based regularizer that employs the transform model, and a data fidelity term formed using the imaging measurements; and store the second image in the computer-readable medium, the second image displayable on a display device.
FILED	Friday, April 03, 2015
APPL NO	14/678876
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 11/006 (20130101) Original (OR) Class G06T 2211/424 (20130101)
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09735236 — Quantum dot channel (QDC) quantum dot gate transistors, memories and other devices

US 09735236	Jain
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	Faquir Chand Jain (Storrs, Connecticut)
ASSIGNEE(S)
INVENTOR(S)	Faquir Chand Jain (Storrs, Connecticut)
ABSTRACT	This invention describes a field-effect transistor in which the channel is formed in an array of quantum dots. In one embodiment the quantum dots are cladded with a thin layer serving as an energy barrier. The quantum dot channel (QDC) may consist of one or more layers of cladded dots. These dots are realized on a single or polycrystalline substrate. When QDC FETs are realized on polycrystalline or nanocrystalline thin films they may yield higher mobility than in conventional nano- or microcrystalline thin films. These FETs can be used as thin film transistors (TFTs) in a variety of applications. In another embodiment QDC-FETs are combined with: (a) coupled quantum well SWS channels, (b) quantum dot gate 3-state like FETs, and (c) quantum dot gate nonvolatile memories.
FILED	Saturday, March 12, 2016
APPL NO	15/068551
ART UNIT	2823 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Static Stores G11C 16/0408 (20130101) G11C 16/0466 (20130101) G11C 2216/06 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/28273 (20130101) H01L 29/125 (20130101) H01L 29/127 (20130101) H01L 29/158 (20130101) Original (OR) Class H01L 29/0665 (20130101) H01L 29/792 (20130101) H01L 29/1054 (20130101) H01L 29/7881 (20130101) H01L 29/42332 (20130101) H01L 29/42348 (20130101) H01L 29/66825 (20130101) H01L 31/028 (20130101) H01L 31/078 (20130101) H01L 31/035218 (20130101) H01L 31/035236 (20130101) H01L 31/035254 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101)
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09735310 — Damage-and-resist-free laser patterning of dielectric films on textured silicon

US 09735310	Bailly
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Mark Scott Bailly (Chandler, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Mark Scott Bailly (Chandler, Arizona)
ABSTRACT	In accordance with embodiments disclosed herein, there are provided methods and systems for implementing damage-and-resist-free laser patterning of dielectric films on textured silicon. For example, in one embodiment, such means include means for depositing a Silicon nitride (SiNx) or SiOx (silicon oxide) layer onto a crystalline silicon (c-Si) substrate by a Plasma Enhanced Chemical Vapor Deposition (PECVD) processing; depositing an amorphous silicon (a-Si) film on top of the SiNx or SiOx layer; patterning the a-Si film to define an etch mask for the SiNx or SiOx layer; removing the SiNx or SiOx layer via a Buffered Oxide Etch (BOE) chemical etch to expose the c-Si surface; removing the a-Si mask with a hydrogen plasma etch in a PECVD tool to prevent current loss from the mask; and plating the exposed c-Si surface with metal contacts. Other related embodiments are disclosed.
FILED	Thursday, September 29, 2016
APPL NO	15/280247
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/028 (20130101) H01L 31/0682 (20130101) H01L 31/1804 (20130101) Original (OR) Class H01L 31/02167 (20130101) H01L 31/022441 (20130101)
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09735783 — Fine-grain dynamically reconfigurable FPGA architecture

US 09735783	Lin et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Ting-Jung Lin (Taipei, Taiwan); Wei Zhang (Hong Kong, China PRC); Niraj K. Jha (Princeton, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S)	Ting-Jung Lin (Taipei, Taiwan); Wei Zhang (Hong Kong, China PRC); Niraj K. Jha (Princeton, New Jersey)
ABSTRACT	A field programmable gate array (FPGA) and method of reconfiguring a FPGA are disclosed. The FPGA includes a plurality of logic elements interconnected with reconfigurable switches and at least horizontal and vertical direct links A memory is coupled to the reconfigurable switches, the memory being configured to store at least two run time configurations. The reconfigurable switches are reconfigurable based on a selected run time configuration stored in the memory. The memory may be a nanoelectronic random access memory (RAM). The memory may be configured to store the at least two run time configurations for at least four logic elements. Each logic element may include a look-up-table (LUT), a flip-flop, inputs and outputs. Each logic element may include dedicated carry logic. At least four logic elements may be interconnected with diagonal direct links.
FILED	Wednesday, December 04, 2013
APPL NO	14/766617
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 19/0008 (20130101) H03K 19/1776 (20130101) Original (OR) Class H03K 19/17728 (20130101) H03K 19/17736 (20130101) H03K 19/17752 (20130101)
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09736128 — System and method for a practical, secure and verifiable cloud computing for mobile systems

US 09736128	Premnath et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); Cornell University (Ithaca, New York)
ASSIGNEE(S)	The Board of Regents, The University of Texas System (Austin, Texas); Center for Technology Licensing at Cornell University (Ithaca, New York)
INVENTOR(S)	Sriram Nandha Premnath (Dallas, Texas); Zygmunt J. Haas (Richardson, Texas)
ABSTRACT	Disclosed are systems and methods for delegating computations of resource-constrained mobile clients, in which multiple servers interact to construct an encrypted program representing a garbled circuit. Implementing the garbled circuit, garbled outputs are returned. Such implementations ensure privacy of each mobile client's data, even if an executing server has been colluded. The garbled circuit provides secure cloud computing for mobile systems by incorporating cryptographically secure pseudo random number generation that enables a mobile client to efficiently retrieve a result of a computation, as well as verify that an evaluator actually performed the computation. Cloud computation and communication complexity are analyzed to demonstrate the feasibility of the proposed system for mobile systems.
FILED	Wednesday, May 20, 2015
APPL NO	14/717619
ART UNIT	2495 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) H04L 63/08 (20130101) H04L 63/062 (20130101) Original (OR) Class H04L 2209/04 (20130101) H04L 2209/46 (20130101) H04L 2209/50 (20130101)
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09736167 — Enhanced security and safety in telerobotic systems

US 09736167	Chizeck et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S)	University of Washington Through its Center For Commercialization (Seattle, Washington)
INVENTOR(S)	Howard Jay Chizeck (Mercer Island, Washington); Tamara Bonaci (Redmond, Washington); Thomas Lendvay (Seattle, Washington)
ABSTRACT	Methods and systems for securing remotely-operable devices are provided. A security device can receive a plurality of commands to control a remotely-operable device in a remote environment. At least one command in the plurality of commands can include command data that is related to the remotely-operable device. The security device can receive a plurality of responses to the plurality of commands. The security device can process the plurality of commands and the plurality of responses to determine a signature related to an operator that issued the plurality of commands for the remotely-operable device. The security device can determine an identity of the operator based on the signature. The security device can generate an identity report that includes the identity of the operator.
FILED	Thursday, September 17, 2015
APPL NO	14/857731
ART UNIT	2433 — Cryptography and Security
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/1689 (20130101) B25J 13/006 (20130101) Electric Digital Data Processing G06F 21/00 (20130101) G06F 21/316 (20130101) G06F 21/552 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 29/06 (20130101) H04L 63/102 (20130101) Original (OR) Class H04L 63/126 (20130101) H04L 63/1425 (20130101)
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National Aeronautics and Space Administration (NASA)

09730582 — Comprehensive oculomotor behavioral response assessment (COBRA)

US 09730582	Stone et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (Washington, District of Columbia)
INVENTOR(S)	Leland S. Stone (San Francisco, California); Dorion B. Liston (Boulder Creek, California)
ABSTRACT	An eye movement-based methodology and assessment tool may be used to quantify many aspects of human dynamic visual processing using a relatively simple and short oculomotor task, noninvasive video-based eye tracking, and validated oculometric analysis techniques. By examining the eye movement responses to a task including a radially-organized appropriately randomized sequence of Rashbass-like step-ramp pursuit-tracking trials, distinct performance measurements may be generated that may be associated with, for example, pursuit initiation (e.g., latency and open-loop pursuit acceleration), steady-state tracking (e.g., gain, catch-up saccade amplitude, and the proportion of the steady-state response consisting of smooth movement), direction tuning (e.g., oblique effect amplitude, horizontal-vertical asymmetry, and direction noise), and speed tuning (e.g., speed responsiveness and noise). This quantitative approach may provide fast and results (e.g., a multi-dimensional set of oculometrics and a single scalar impairment index) that can be interpreted by one without a high degree of scientific sophistication or extensive training.
FILED	Tuesday, May 12, 2015
APPL NO	14/710260
ART UNIT	2872 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/032 (20130101) A61B 3/0041 (20130101) A61B 3/0091 (20130101) A61B 3/113 (20130101) Original (OR) Class
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09732316 — Devices and methods for pharmacokinetic-based cell culture system

US 09732316	Shuler et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S)	Michael Shuler (Ithaca, New York); Gregory T. Baxter (Salinas, California); Aaron Sin (Ithaca, New York); Robert Andrew Harrison (Toronto, Canada); Scott Meyers (Norristown, Pennsylvania)
ABSTRACT	A cell culture device comprising a microscale chamber dimensioned to maintain a cell under conditions that give rise to a value for at least one pharmacokinetic parameter in vitro that is comparable to a value for the same at least one pharmacokinetic parameter obtained with respect to the same type of cell in vivo, wherein the microscale chamber is configured for flow of culture medium, and wherein the at least one pharmacokinetic parameter is selected from tissue size ratio, tissue to blood volume ratio, drug residence time, flow rate, circulatory transit time, liquid residence time, and liquid to cell ratio.
FILED	Friday, February 26, 2016
APPL NO	15/055385
ART UNIT	1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 23/44 (20130101) C12M 41/46 (20130101) Original (OR) Class C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0671 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/5067 (20130101)
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09733141 — Method for making measurements of the post-combustion residence time in a gas turbine engine

US 09733141	Miles
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Jeffrey H. Miles (Beachwood, Ohio)
ABSTRACT	A method of measuring a residence time in a gas-turbine engine is disclosed that includes measuring a combustor pressure signal at a combustor entrance and a turbine exit pressure signal at a turbine exit. The method further includes computing a cross-spectrum function between the combustor pressure signal and the turbine exit pressure signal, calculating a slope of the cross-spectrum function, shifting the turbine exit pressure signal an amount corresponding to a time delay between the measurement of the combustor pressure signal and the turbine exit pressure signal, and recalculating the slope of the cross-spectrum function until the slope reaches zero.
FILED	Thursday, April 23, 2015
APPL NO	14/694235
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 11/04 (20130101) Original (OR) Class Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101)
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09733203 — Wireless chemical sensing method

US 09733203	Woodard et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (Washington, District of Columbia)
INVENTOR(S)	Stanley E. Woodard (Hampton, Virginia); Donald M. Oglesby (Hertford, Virginia); Bryant D. Taylor (Smithfield, Virginia)
ABSTRACT	A wireless chemical sensor includes an electrical conductor and a material separated therefrom by an electric insulator. The electrical conductor is an unconnected open-circuit shaped for storage of an electric field and a magnetic field. In the presence of a time-varying magnetic field, the first electrical conductor resonates to generate harmonic electric and magnetic field responses. The material is positioned at a location lying within at least one of the electric and magnetic field responses so-generated. The material changes in electrical conductivity in the presence of a chemical-of-interest.
FILED	Thursday, April 28, 2016
APPL NO	15/141217
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/021 (20130101) G01N 27/26 (20130101) Original (OR) Class G01N 27/72 (20130101) G01N 27/122 (20130101)
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09734932 — Negative dielectric constant material based on ion conducting materials

US 09734932	Gordon et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Keith L. Gordon (Hampton, Virginia); Jin Ho Kang (Newport News, Virginia); Cheol Park (Yorktown, Virginia); Peter T. Lillehei (Newport News, Virginia); Joycelyn S. Harrison (Arlington, Virginia)
ABSTRACT	Metamaterials or artificial negative index materials (NIMs) have generated great attention due to their unique and exotic electromagnetic properties. One exemplary negative dielectric constant material, which is an essential key for creating the NIMs, was developed by doping ions into a polymer, a protonated poly (benzimidazole) (PBI). The doped PBI showed a negative dielectric constant at megahertz (MHz) frequencies due to its reduced plasma frequency and an induction effect. The magnitude of the negative dielectric constant and the resonance frequency were tunable by doping concentration. The highly doped PBI showed larger absolute magnitude of negative dielectric constant at just above its resonance frequency than the less doped PBI.
FILED	Tuesday, April 15, 2014
APPL NO	14/253317
ART UNIT	1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/18 (20130101) Compositions of Macromolecular Compounds C08L 79/04 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0009 (20130101) G02F 2202/30 (20130101) G02F 2202/42 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) H01B 3/12 (20130101) H01B 3/38 (20130101) Original (OR) Class
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09735612 — Remotely powered reconfigurable receiver for extreme sensing platforms

US 09735612	Sheldon
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Douglas J. Sheldon (Valencia, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Douglas J. Sheldon (Valencia, California)
ABSTRACT	Unmanned space programs are currently used to enable scientists to explore and research the furthest reaches of outer space. Systems and methods for low power communication devices in accordance with embodiments of the invention are disclosed, describing a wide variety of low power communication devices capable of remotely collecting, processing, and transmitting data from outer space in order to further mankind's goal of exploring the cosmos. Many embodiments of the invention include a Flash-based FPGA, an energy-harvesting power supply module, a sensor module, and a radio module. By utilizing technologies that withstand the harsh environment of outer space, more reliable low power communication devices can be deployed, enhancing the quality and longevity of the low power communication devices, enabling more data to be gathered and aiding in the exploration of outer space.
FILED	Tuesday, October 25, 2011
APPL NO	13/281331
ART UNIT	2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/345 (20130101) Original (OR) Class H02J 17/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) Y10S 901/46 (20130101)
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Small Business Administration (SBA)

09733543 — Sub-volt drive 100 GHz bandwidth electro-optic modulator

US 09733543	Dagli
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Nadir Dagli (Goleta, California)
ABSTRACT	Electro-optical modulators and methods of fabrication are disclosed. An electro-optical modulator includes a Mach-Zehnder interferometer formed in a substrate removed semiconductor layer and a coplanar waveguide. Signals from the coplanar waveguide are capacitively coupled to the Mach-Zehnder interferometer through first and second dielectric layers.
FILED	Wednesday, October 05, 2016
APPL NO	15/286275
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/42 (20130101) G02B 6/125 (20130101) G02B 6/132 (20130101) G02B 2006/1204 (20130101) G02B 2006/12047 (20130101) G02B 2006/12054 (20130101) G02B 2006/12078 (20130101) G02B 2006/12128 (20130101) G02B 2006/12142 (20130101) G02B 2006/12159 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0121 (20130101) G02F 1/01708 (20130101) G02F 1/2255 (20130101) Original (OR) Class G02F 1/2257 (20130101) G02F 2001/212 (20130101) G02F 2201/12 (20130101) G02F 2202/20 (20130101) G02F 2202/42 (20130101)
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09735022 — Arrays of long nanostructures in semiconductor materials and methods thereof

US 09735022	Yi et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Alphabet Energy, Inc. (Hayward, California)
ASSIGNEE(S)	ALPHABET ENERGY, INC. (Hayward, California)
INVENTOR(S)	Mingqiang Yi (San Pablo, California); Matthew L. Scullin (San Francisco, California); Gabriel Matus (San Francisco, California); Dawn L. Hilken (Pleasant Hill, California); Chii Guang Lee (Fremont, California); Sylvain Muckenhirn (Santa Barbara, California)
ABSTRACT	An array of nanowires and method thereof. The array of nanowires includes a plurality of nanowires. The plurality of nanowires includes a plurality of first ends and a plurality of second ends respectively. For each of the plurality of nanowires, a corresponding first end selected from the plurality of first ends and a corresponding second end selected from the plurality of second ends are separated by a distance of at least 200 μm. All nanowires of the plurality of nanowires are substantially parallel to each other.
FILED	Thursday, December 11, 2014
APPL NO	14/567793
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3081 (20130101) H01L 21/3085 (20130101) H01L 21/3086 (20130101) Original (OR) Class H01L 27/16 (20130101) H01L 29/0676 (20130101) H01L 31/035227 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2913 (20150115) Y10T 428/24802 (20150115) Y10T 428/249924 (20150401)
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09735466 — Advanced composite radome and method of manufacturing

US 09735466	Johnson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Ebert Composites Corporation (Chula Vista, California)
ASSIGNEE(S)	Ebert Composites Corporation (Chula Vista, California)
INVENTOR(S)	David W. Johnson (San Diego, California); Scott A. Garrett (San Diego, California); Stephen G. Moyers (Jamul, California)
ABSTRACT	A radome for housing a radar system comprises a plurality of interconnected curved radome thermoplastic composite material panels, each curved radome thermoplastic composite material panel having a plurality of interconnecting edges, a foam core, an inner skin, an outer skin, and a plurality of three-dimensional fiber bundles tying the inner skin and the outer skin to each other through the foam core, inhibiting delamination. The radome includes a hydrophobic exterior surface that is self-cleaning and requires zero maintenance for 25 years.
FILED	Wednesday, July 16, 2014
APPL NO	14/333182
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 51/268 (20130101) B29C 65/562 (20130101) B29C 66/43 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/543 (20130101) B29C 66/721 (20130101) B29C 66/723 (20130101) B29C 66/1142 (20130101) B29C 66/7212 (20130101) B29C 66/7212 (20130101) B29C 66/7392 (20130101) B29C 66/8246 (20130101) B29C 66/72141 (20130101) B29C 66/73921 (20130101) B29C 66/83221 (20130101) B29C 67/0044 (20130101) B29C 70/086 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/12 (20130101) B29K 2027/18 (20130101) B29K 2067/003 (20130101) B29K 2067/003 (20130101) B29K 2071/00 (20130101) B29K 2077/00 (20130101) B29K 2079/085 (20130101) B29K 2081/04 (20130101) B29K 2105/256 (20130101) B29K 2309/08 (20130101) B29K 2309/08 (20130101) B29K 2995/0094 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/773 (20130101) B29L 2031/3456 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/0012 (20130101) Antennas, i.e Radio Aerials H01Q 1/42 (20130101) Original (OR) Class H01Q 1/424 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1036 (20150115)
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09735549 — Methods for forming photonic integrated circuits based on quantum cascade structures

US 09735549	Goyal et al.
FUNDED BY	Department of Defense (DOD) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Pendar Technologies, LLC (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Pendar Technologies, LLC (Cambridge, Massachusetts)
INVENTOR(S)	Anish K. Goyal (Cambridge, Massachusetts); Laurent Diehl (Somerville, Massachusetts); Christian Pfluegl (Medford, Massachusetts); Christine A. Wang (Bedford, Massachusetts); Mark Francis Witinski (Cambridge, Massachusetts)
ABSTRACT	Photonic integrated circuits (PICs) are based on quantum cascade (QC) structures. In embodiment methods and corresponding devices, a QC layer in a wave confinement region of an integrated multi-layer semiconductor structure capable of producing optical gain is depleted of free charge carriers to create a low-loss optical wave confinement region in a portion of the structure. Ion implantation may be used to create energetically deep trap levels to trap free charge carriers. Other embodiments include modifying a region of a passive, depleted QC structure to produce an active region capable of optical gain. Gain or loss may also be modified by partially depleting or enhancing free charge carrier density. QC lasers and amplifiers may be integrated monolithically with each other or with passive waveguides and other passive devices in a self-aligned manner. Embodiments overcome challenges of high cost, complex fabrication, and coupling loss involved with material re-growth methods.
FILED	Wednesday, July 27, 2016
APPL NO	15/221402
ART UNIT	2894 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/15 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/026 (20130101) H01S 5/2018 (20130101) H01S 5/2063 (20130101) H01S 5/2275 (20130101) H01S 5/3013 (20130101) H01S 5/3402 (20130101) Original (OR) Class
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Department of Veterans Affairs (DVA)

09730988 — Parasitic biological agents for treatment and prevention of graft versus host disease

US 09730988	Ince et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S)	University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S)	Mirac Nedim Ince (Iowa City, Iowa); David E. Elliott (North Liberty, Iowa); George J. Weiner (Iowa City, Iowa)
ABSTRACT	The invention relates to helminthic parasite preparations and their use for treatment or prevention of GVHD in a subject that has undergone a transplant. The invention also related to helminthic parasite preparations and their use for prevention of GVHD in a subject prior to a transplant.
FILED	Friday, April 10, 2015
APPL NO	14/683778
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/001 (20130101) A61K 39/0003 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/577 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/6863 (20130101) G01N 33/6866 (20130101) G01N 33/56972 (20130101) G01N 2333/57 (20130101) G01N 2333/525 (20130101) G01N 2800/52 (20130101) G01N 2800/245 (20130101)
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09732146 — Antibody-mediated transduction of heat shock proteins into living cells

US 09732146	Nishimura et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Robert N. Nishimura (Sepulveda, California); Richard H. Weisbart (Sepulveda, California); James Hansen (Guilford, Connecticut)
ASSIGNEE(S)	The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Robert N. Nishimura (Sepulveda, California); Richard H. Weisbart (Sepulveda, California); James Hansen (Guilford, Connecticut)
ABSTRACT	The invention provides for a fusion protein comprising a 3E10 Fv joined to a Hsp-70, Hsp-27, Hsp-90 or GRP-78 or portion thereof, and optionally, the 3E10 Fv comprising an amino acid sequence AGIH at its amino terminus.
FILED	Friday, March 15, 2013
APPL NO	13/815829
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/48538 (20130101) Peptides C07K 14/47 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/56 (20130101) C07K 2317/77 (20130101) C07K 2317/622 (20130101) C07K 2319/33 (20130101)
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National Security Agency (NSA)

09733995 — Scalable synchronization mechanism for distributed memory

US 09733995	Cole et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Clement T. Cole (Chelmford, Massachusetts); James Dinan (Hudson, Massachusetts); Gabriele Jost (Santa Clara, California); Stanley C. Smith (Hillsboro, Oregon); Robert W. Wisniewski (Ossining, New York); Keith D. Underwood (Albuquerque, New Mexico)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Clement T. Cole (Chelmford, Massachusetts); James Dinan (Hudson, Massachusetts); Gabriele Jost (Santa Clara, California); Stanley C. Smith (Hillsboro, Oregon); Robert W. Wisniewski (Ossining, New York); Keith D. Underwood (Albuquerque, New Mexico)
ABSTRACT	A method comprising receiving control information at a first processing element from a second processing element, synchronizing objects within a shared global memory space of the first processing element with a shared global memory space of a second processing element in response to receiving the control information and generating a completion event indicating the first processing element has been synchronized with the second processing element.
FILED	Wednesday, December 17, 2014
APPL NO	14/573133
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class G06F 12/06 (20130101) G06F 12/0692 (20130101) G06F 2212/1016 (20130101)
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09734069 — Multicast tree-based data distribution in distributed shared cache

US 09734069	Steely, Jr. et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Simon C. Steely, Jr. (Hudson, New Hampshire); William C. Hasenplaugh (Boston, Massachusetts); Samantika S. Sury (Westford, Massachusetts)
ABSTRACT	Systems and methods for multicast tree-based data distribution in a distributed shared cache. An example processing system comprises: a plurality of processing cores, each processing core communicatively coupled to a cache; a tag directory associated with caches of the plurality of processing cores; a shared cache associated with the tag directory; a processing logic configured, responsive to receiving an invalidate request with respect to a certain cache entry, to: allocate, within the shared cache, a shared cache entry corresponding to the certain cache entry; transmit, to at least one of: a tag directory or a processing core that last accessed the certain entry, an update read request with respect to the certain cache entry; and responsive to receiving an update of the certain cache entry, broadcast the update to at least one of: one or more tag directories or one or more processing cores identified by a tag corresponding to the certain cache entry.
FILED	Thursday, December 11, 2014
APPL NO	14/567026
ART UNIT	2135 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 12/084 (20130101) Original (OR) Class G06F 12/0815 (20130101) G06F 12/0822 (20130101) G06F 2212/281 (20130101) G06F 2212/1021 (20130101)
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Department of Agriculture (USDA)

09730438 — Container apparatus

US 09730438	Messaros et al.
FUNDED BY	Department of Agriculture (USDA) Animal and Plant Health Inspection Service (APHIS)
APPLICANT(S)	Applied Design Corporation (Boulder, Colorado); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	Applied Design Corporation (Boulder, Colorado); The United States of America, As Represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Michael C. Messaros (Erie, Colorado); Grady E. Barfoot (Denver, Colorado); Jonathan C. Fragoso (Thornton, Colorado); Peter J. Savarie (Lakewood, Colorado); William C. Pitt (Middleton, Virginia)
ABSTRACT	A container apparatus for exposing an article to an external environment, the apparatus including a sidewall with an interior having an inner surface, the sidewall terminating in a first margin and an opposing second margin. The container apparatus also includes a capsule having an outer periphery and an inner void holding the article, the outer periphery is slidably engaged to the sidewall inner surface, the capsule having a split boundary separating the capsule into a plurality of partial capsule elements. The capsule having a closed state with the partial capsule elements being adjacent at the boundary while slidably engaged to the sidewall with the void separated from the environment and the capsule being able to have an open state without the slidable engagement as the partial capsule elements are separated at the boundary with the void open to the environment, thus exposing the article to the environment.
FILED	Tuesday, January 20, 2015
APPL NO	14/601210
ART UNIT	3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 25/00 (20130101) A01M 25/002 (20130101) A01M 25/006 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Department of Commerce (DOC)

09734118 — Serial bus interface to enable high-performance and energy-efficient data logging

US 09734118	Yoon et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Eunbae Yoon (Irvine, California); Pai H. Chou (Irvine, California)
ABSTRACT	A new serial bus interface module that enables constrained sensor systems to better match flash-based storage devices' (SD card) read and write performance. The serial bus interface module augments existing flash-based storage with non-volatile random-access memory to form a hybrid storage system using the most popularly used master-slave bus architecture. Together with PSC-like features, the serial bus interface module not only enables slave-to-slave transfer (therefore eliminating the double-transaction problem) but also reads caching (one source to multi-sink) and buffering while flushing. These transaction types enable multi-sector write for significantly faster speed and lower energy overhead, while the use of non-volatile memory for metadata caching means low risk of file-system corruption in the event of power failure. The serial bus interface also enables the direct data transfer from sensors to storage or communication modules without requiring the microprocessor's intervention.
FILED	Wednesday, October 15, 2014
APPL NO	14/515330
ART UNIT	2181 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 11/3476 (20130101) G06F 12/0238 (20130101) G06F 12/0246 (20130101) G06F 12/0804 (20130101) G06F 12/0868 (20130101) G06F 13/287 (20130101) G06F 13/385 (20130101) G06F 13/1673 (20130101) G06F 13/4282 (20130101) Original (OR) Class G06F 2212/62 (20130101) G06F 2212/214 (20130101) G06F 2212/222 (20130101) G06F 2212/463 (20130101) G06F 2212/466 (20130101) G06F 2212/7203 (20130101) G06F 2212/7208 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/1225 (20130101) Y02B 60/1228 (20130101) Y02B 60/1235 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Environmental Protection Agency (EPA)

09733239 — Reconfigurable microfluidic systems: scalable, multiplexed immunoassays

US 09733239	Jiao et al.
FUNDED BY	Environmental Protection Agency (EPA)
APPLICANT(S)	Hong Jiao (Santa Clara, California); Erik C Jensen (Berkeley, California); Homayun Mehrabani (Emeryville, California); Liran Yosef Haller (Berkeley, California)
ASSIGNEE(S)	HJ Science and Technology, Inc. (Berkeley, California)
INVENTOR(S)	Hong Jiao (Santa Clara, California); Erik C Jensen (Berkeley, California); Homayun Mehrabani (Emeryville, California); Liran Yosef Haller (Berkeley, California)
ABSTRACT	Reconfigurable microfluidic systems are based on networks of microfluidic cavities connected by hydrophobic microfluidic channels. Each cavity is classified as either a reservoir or a node, and includes a pressure port via which gas pressure may be applied. Sequences of gas pressures, applied to reservoirs and nodes according to a fluid transfer rule, enable fluid to be moved from any reservoir to any other reservoir in a system. Systems may be configured with multiple switched interaction regions connected in series for scalable, multiplexed immunoassays. Multiple, switched interaction regions may also be implemented with microvalves.
FILED	Friday, July 24, 2015
APPL NO	14/808939
ART UNIT	1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502738 (20130101) B01L 3/502746 (20130101) B01L 2200/027 (20130101) B01L 2300/14 (20130101) B01L 2300/165 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/088 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/536 (20130101) G01N 33/5302 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Smithsonian Institution (SI)

09730970 — Seaweed extracts, unsaturated aldehydes, and methods of treatment

US 09730970	Luesch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) Smithsonian Institution (SI)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); Smithsonian Institution (Washington, District of Columbia)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); Smithsonian Institution (Washington, District of Columbia)
INVENTOR(S)	Hendrik Luesch (Gainesville, Florida); Valerie J. Paul (Fort Pierce, Florida); Ranjala Ratnayake (Gainesville, Florida)
ABSTRACT	The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated diseases and diseases mediated through the activation of the Nrf2-ARE (antioxidant response element) pathway, including proliferative diseases and disorders, Alzheimer's disease, stroke, and certain diseases and disorders of aging and associated with aging and exposure, by use of the extracts, compounds, and compositions thereof.
FILED	Friday, March 14, 2014
APPL NO	14/846544
ART UNIT	1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/11 (20130101) A61K 36/02 (20130101) A61K 36/05 (20130101) Original (OR) Class A61K 2236/33 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

09733647 — System and method of control of electronic parcel lockers

US 09733647	Irwin et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)	The United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	Donald E. Irwin (Fredericksburg, Virginia); Nan K. McKenzie (Garrett Park, Maryland); William A. Tartal (Baltimore, Maryland); Victoria K. Stephen (Burke, Virginia); Michael J. Amato (Reston, Virginia)
ABSTRACT	A system, apparatus, and method for use in delivery of items to a storage unit. The storage unit can include one or several storage receptacles and a control unit that controls and monitors the status of the one or several storage receptacles. The storage unit may be included in a storage unit system that can include one or several storage units and a central control unit. The central control unit can communicate with the one or several storage units, and can receive status and availability updates from the one or several storage units.
FILED	Wednesday, December 05, 2012
APPL NO	13/706281
ART UNIT	2682 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 1/0485 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 3/00 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/00 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0836 (20130101) Coin-freed or Like Apparatus G07F 7/08 (20130101) G07F 17/10 (20130101) G07F 17/12 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

09731811 — Payload shroud for air vehicle

US 09731811	Atzert et al.
FUNDED BY
APPLICANT(S)	AAI Corporation (Hunt Valley, Maryland)
ASSIGNEE(S)	AAI Corporation (Hunt Valley, Maryland)
INVENTOR(S)	Monica Atzert (Shrewsbury, Pennsylvania); Jason Wallace (Cockeysville, Maryland); Robert Hurn (Baltimore, Maryland); Doug Deardorff (Phoenix, Maryland); Terry Zeleny (Nottingham, Maryland)
ABSTRACT	A UAV includes a body. The body defines a payload opening 14. The payload opening is circular, but any shape may be used. A payload of the UAV is arranged in the payload opening. The payload may be a camera, sensors, a package, etc. A payload shroud may be installed which prohibits or reduced ingress of foreign material via payload opening. A payload shroud may include a diverter. The diverter may act as a barrier wall preventing the water or debris from entering the body of the UAV. The diverter should fit flush with the payload opening in the body of the UAV.
FILED	Friday, December 13, 2013
APPL NO	14/105988
ART UNIT	3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeroplanes; Helicopters B64C 1/36 (20130101) B64C 7/00 (20130101) Original (OR) Class B64C 39/024 (20130101) B64C 2201/021 (20130101) B64C 2201/123 (20130101) B64C 2201/128 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/08 (20130101) B64D 47/08 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09732427 — Tunable nanoporous films on polymer substrates, and method for their manufacture

US 09732427	Poxson et al.
FUNDED BY
APPLICANT(S)	David J. Poxson (Troy, New York); Frank W. Mont (Troy, New York); E. Fred Schubert (Troy, New York); Richard W. Siegel (Menands, New York)
ASSIGNEE(S)	RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
INVENTOR(S)	David J. Poxson (Troy, New York); Frank W. Mont (Troy, New York); E. Fred Schubert (Troy, New York); Richard W. Siegel (Menands, New York)
ABSTRACT	The invention is directed to a composite polymer/nanoporous film system and methods of fabrication of tunable nanoporous coatings on flexible polymer substrates. The porosity of the nanoporous film can be tuned during fabrication to a desired value by adjusting the deposition conditions. Experiments show that SiO₂coatings with tunable porosity fabricated by oblique-angle electron beam deposition can be deposited on polymer substrates. These conformable coatings have many applications, including in the field of optics where the ability to fabricate tunable refractive index coatings on a variety of materials and shapes is of great importance.
FILED	Thursday, August 25, 2011
APPL NO	13/817922
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/10 (20130101) C23C 14/34 (20130101) C23C 14/083 (20130101) C23C 14/226 (20130101) C23C 14/325 (20130101) C23C 16/44 (20130101) C23C 16/50 (20130101) C23C 16/487 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 50/67 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24997 (20150401) Y10T 428/249967 (20150401) Y10T 428/249969 (20150401) Y10T 428/249978 (20150401)
VIEW PATENT	@ USPTO: Full Text PDF

09734166 — Association of visual labels and event context in image data

US 09734166	Cao et al.
FUNDED BY
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Liangliang Cao (Yorktown Heights, New York); Yuan-Chi Chang (Armonk, New York); Quoc-Bao Nguyen (Stamford, Connecticut)
ABSTRACT	A first set of contextual dimensions is generated from one or more textual descriptions associated with a given event, which includes one or more examples. A second set of contextual dimensions is generated from one or more visual features associated with the given event, which includes one or more visual example recordings. A similarity structure is constructed from the first set of contextual dimensions and the second set of contextual dimensions. One or more of the textual descriptions is matched with one or more of the visual features based on the similarity structure.
FILED	Monday, August 26, 2013
APPL NO	13/975497
ART UNIT	2155 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/30017 (20130101) G06F 17/30038 (20130101) G06F 17/30268 (20130101) Original (OR) Class G06F 17/30855 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09736923 — Alloy bonded graphene sheets for enhanced thermal spreaders

US 09736923	Starkovich et al.
FUNDED BY
APPLICANT(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S)	Northrop Grumman Systems Corporation (Fall Church, Virginia)
INVENTOR(S)	John A. Starkovich (Redondo Beach, California); Jesse B. Tice (Torrance, California); Xianglin Zeng (Monterey Park, California); Andrew D. Kostelec (Fullerton, California); Hsiao-Hu Peng (Rancho Palos Verdes, California); Edward M. Silverman (Encino, California)
ABSTRACT	A heat spreader for printed wiring boards and a method of manufacture are disclosed. The heat spreader is made from a plurality of graphene sheets that are thermo-mechanically bonded using an alloy bonding process that forms a metal alloy layer using a low temperature and pressure that does not damage the graphene sheets. The resulting heat spreader has a higher thermal conductivity than graphene sheets alone.
FILED	Tuesday, January 17, 2017
APPL NO	15/407299
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/02 (20130101) F28F 2255/06 (20130101) F28F 2275/02 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0204 (20130101) Original (OR) Class H05K 2201/06 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

What You'll Find On This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, August 15, 2017.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20170815.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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