FedInvent™ Patents

Patent Details for Tuesday, October 31, 2017

This page was updated on Monday, March 27, 2023 at 05:20 AM GMT

Department of Defense (DOD)

09801591 — Fast iterative algorithm for superresolving computed tomography with missing data

US 09801591	Holmes et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Lickenbrock Technologies, LLC (Saint Louis, Missouri)
ASSIGNEE(S)	Lickenbrock Technologies, LLC (St. Louis, Missouri)
INVENTOR(S)	Timothy J. Holmes (Saint Louis, Missouri); Sean M. Larkin (Saint Louis, Missouri)
ABSTRACT	Disclosed is a method, program product, and computer system that provides iterative computed tomography (CT) image reconstruction. The approach produces an image whose resolving power exceeds that of conventional algorithms, and utilizes an inner and out iterative loop, configured by ordered subsets criteria, to perform: projecting a reconstructed image; resampling a resulting calculated projection, thereby enabling super-resolution; calculating a comparison quantity with the collected projection array (e.g., sinogram); backprojecting onto a correction array a function that utilizes the comparison quantity; and generating a new reconstructed image with an operation involving the correction array.
FILED	Friday, October 31, 2014
APPL NO	14/529452
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 6/027 (20130101) A61B 6/032 (20130101) Original (OR) Class A61B 6/037 (20130101) A61B 6/5205 (20130101) Image Data Processing or Generation, in General G06T 11/006 (20130101) G06T 2211/436 (20130101)
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09801893 — Method of treatment for prostate cancer with androgen receptor antagonists and glucocorticoid receptor antagonists

US 09801893	Szmulewitz et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The University of Chicago (Chicago, Illinois)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois)
INVENTOR(S)	Russell Z. Szmulewitz (Chicago, Illinois); Suzanne D. Conzen (Park Ridge, Illinois)
ABSTRACT	Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity.
FILED	Tuesday, February 02, 2016
APPL NO	15/013660
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/567 (20130101) Original (OR) Class A61K 31/567 (20130101) A61K 31/569 (20130101) A61K 31/569 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/4166 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101)
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09801909 — Compositions and methods for combating bacterial infections by killing persister cells with mitomycin C

US 09801909	Wood et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Thomas Wood (Port Matilda, Pennsylvania); Brian Kwan (State College, Pennsylvania); Nityananda Chowdhury (State College, Pennsylvania)
ABSTRACT	The present disclosure provides a method for killing persister cells with mitomycin C and/or cisplatin, or derivatives thereof. Recalcitrant infections are difficult to treat due to persister cells, a subpopulation of all bacterial populations that is highly tolerant against all traditional antibiotics since the cells are dormant and antibiotics are designed to kill growing cells. Here, we show that MMC and cisplatin eradicate persister cells through a growth-independent mechanism, cross-linking DNA. We find both agents are effective against both planktonic cultures and highly robust biofilm cultures for a broad range of bacterial species, including commensal Escherichia coli K-12 as well as pathogenic species of E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In certain approaches cisplatin is superior to MMC.
FILED	Friday, April 01, 2016
APPL NO	15/088915
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/33 (20130101) A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 33/24 (20130101) Original (OR) Class A61K 33/24 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09801931 — Methods and compositions based on Shiga toxin type 2 protein

US 09801931	O'Brien et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S)	Alison D. O'Brien (Bethesda, Maryland); Angela Melton-Celsa (Sterling, Virginia); Michael Smith (Silver Spring, Maryland); James Sinclair (Baltimore, Maryland)
ABSTRACT	The invention is based on the discovery of the epitope in the Stx2 protein for the 11 E1O antibody. The invention features compositions containing non-full length Stx2 polypeptides that include the 11 E1O monoclonal antibody epitope. The invention also features methods of producing anti-Stx2 antibodies specific for the 11 E1O epitope of the Stx2 protein. Additionally, the invention features methods for treating a subject having, or at risk of developing, a Shiga toxin associated disease (e.g., hemolytic uremia syndrome and diseases associated with E. coli and S. dysenteriae infection) with a polypeptide that includes the 11 E1O epitope or with an anti-Stx2 antibody developed using the methods of the invention. Furthermore, the invention features the detection of Stx2 in a sample using the antibodies developed using the methods of the invention.
FILED	Monday, February 23, 2015
APPL NO	14/628667
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0258 (20130101) A61K 39/0283 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/25 (20130101) C07K 16/1232 (20130101) C07K 2317/34 (20130101)
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09801946 — Synthetic polyurethane composite

US 09801946	Guelcher et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Scott A. Guelcher (Thompson Station, Tennessee); Jerald Dumas (Nashville, Tennessee); Edna M. Prieto (Nashville, Tennessee); Anne Talley (Nashville, Tennessee); Andrew Harmata (Nashville, Tennessee); Katarzyna Zienkiewicz (Nashville, Tennessee)
ABSTRACT	Embodiments of the present inventions comprise composites of polyurethane(s), osteoconductive matrix, and, optionally, a growth factor. Embodiments further comprise methods of making such composite and uses thereof. The osteoconductive matrix can be a tricalcium phosphate, bioglass, or the like, and can include particles that are surface modified. Growth factors can be provided in powder form, including bone morphogenic proteins such as rhBMP-2. A composition may be moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells.
FILED	Monday, April 22, 2013
APPL NO	13/868077
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) A61K 38/1875 (20130101) A61K 47/02 (20130101) A61K 47/46 (20130101) Original (OR) Class
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09801957 — Lipid-based nanoparticles

US 09801957	Annapragada et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Ananth Annapragada (Manvel, Texas); Jason L. Eriksen (Houston, Texas); Eric A. Tanifum (Katy, Texas); Indrani Dasgupta (Frederick, Maryland); Stephen C. Cook (Houston, Texas)
ASSIGNEE(S)
INVENTOR(S)	Ananth Annapragada (Manvel, Texas); Jason L. Eriksen (Houston, Texas); Eric A. Tanifum (Katy, Texas); Indrani Dasgupta (Frederick, Maryland); Stephen C. Cook (Houston, Texas)
ABSTRACT	Lipid-based nanoparticle compositions are provided. The compositions generally comprise lipid-hydrophilic polymer-amyloid binding ligand conjugates, and may be liposomal compositions. The compositions, including the liposomal compositions, may be useful for imaging and/or the treatment of amyloid-β plaque deposits characteristic of Alzheimer's Disease.
FILED	Friday, April 06, 2012
APPL NO	13/441816
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48815 (20130101) A61K 49/0466 (20130101) A61K 49/1812 (20130101) Original (OR) Class
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09802254 — Zinc electrodes for batteries

US 09802254	Rolison et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Debra R. Rolison (Arlington, Virginia); Joseph F. Parker (Washington, District of Columbia); Jeffrey W. Long (Alexandria, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Debra R. Rolison (Arlington, Virginia); Joseph F. Parker (Washington, District of Columbia); Jeffrey W. Long (Alexandria, Virginia)
ABSTRACT	A method of: providing an emulsion having a zinc powder and a liquid phase; drying the emulsion to form a sponge; sintering the sponge in an inert atmosphere to form a sintered sponge; heating the sintered sponge in an oxidizing atmosphere to form an oxidized sponge having zinc oxide on the surface of the oxidized sponge; and heating the oxidized sponge in an inert atmosphere at above the melting point of the zinc. A method of: providing an emulsion comprising a zinc powder and a liquid phase; placing the emulsion into a mold, wherein the emulsion is in contact with a metal substrate; and drying the emulsion to form a sponge.
FILED	Tuesday, September 30, 2014
APPL NO	14/501629
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0074 (20130101) B22F 3/11 (20130101) B22F 3/11 (20130101) B22F 3/1017 (20130101) B22F 3/1017 (20130101) B22F 3/1143 (20130101) B22F 3/1146 (20130101) B22F 3/1146 (20130101) B22F 7/002 (20130101) B22F 7/04 (20130101) Original (OR) Class B22F 7/008 (20130101) B22F 2201/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/16 (20130101) C25C 5/00 (20130101) C25C 5/00 (20130101) C25C 5/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/26 (20130101) H01M 4/244 (20130101) H01M 4/0471 (20130101) H01M 4/628 (20130101) H01M 12/08 (20130101) H01M 12/065 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/128 (20130101)
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09802374 — Biopolymer sensor and method of manufacturing the same

US 09802374	Kaplan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Tufts University (Medford, Massachusetts)
ASSIGNEE(S)	TUFTS UNIVERSITY (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Fiorenzo Omenetto (Lexington, Massachusetts); Brian Lawrence (New York, New York); Mark Cronin-Golomb (Reading, Massachusetts); Irene Georgakoudi (Acton, Massachusetts)
ABSTRACT	A method of manufacturing a biopolymer sensor including providing a biopolymer, processing the biopolymer to yield a biopolymer matrix solution, adding a biological material in the biopolymer matrix, providing a substrate, casting the matrix solution on the substrate, and drying the biopolymer matrix solution to form a solidified biopolymer sensor on the substrate. A biopolymer sensor is also provided that includes a solidified biopolymer film with an embedded biological material.
FILED	Friday, August 09, 2013
APPL NO	13/963952
ART UNIT	1677 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/02 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) Original (OR) Class
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09802525 — Rotor blade stands

US 09802525	Gill, III
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S)	Frank Joseph Gill, III (Conshohocken, Pennsylvania)
ABSTRACT	Example stands for supporting a component, such as a rotor blade, are described herein. An example stand described herein includes a blade support having an opening extending from an edge of the blade support towards a center of the blade support. The opening is to receive a rotor blade of an aircraft, for example. The example stand also includes a base to support the blade support above a supporting surface. The blade support is rotatably coupled to the base about a horizontal axis perpendicular to a central axis of the blade support such that the blade support can tilt the rotor blade relative to the supporting surface.
FILED	Tuesday, March 01, 2016
APPL NO	15/057667
ART UNIT	3632 — Static Structures, Supports and Furniture
CURRENT CPC	Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects B60P 3/00 (20130101) Original (OR) Class B60P 3/40 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/0009 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/28 (20130101) F16M 11/041 (20130101) F16M 11/42 (20130101) F16M 11/125 (20130101) F16M 2200/08 (20130101)
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09802698 — Rotor hub for rotary wing aircraft

US 09802698	Capelle et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S)	SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S)	Steven M. Capelle (Derby, Connecticut); Kwok Chin (Stamford, Connecticut); Kevin A. White (Shelton, Connecticut)
ABSTRACT	A rotor hub configured to support and rotate a plurality of rotor blades about an axis of rotation is includes a cylindrical body having a central shaft hole including the axis of rotation. The shaft hole has a radius extending from the axis of rotation radially. A plurality of radial spokes extends from the cylindrical body in a spoke direction. A plurality of arcuate segments extends between the distal ends of adjacent spokes to define a plurality of hub apertures. The spoke direction extends at an angle to the radial direction in both the horizontal plane, and a vertical plane, perpendicular to the horizontal plane. A line defined by the spoke direction does not intersect the axis of rotation. The spoke direction extends at an angle in the horizontal plane in a direction opposite to a direction of rotation of the rotor hub about the axis of rotation.
FILED	Monday, October 12, 2015
APPL NO	14/880921
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Aeroplanes; Helicopters B64C 27/32 (20130101) B64C 27/35 (20130101) Original (OR) Class
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09802818 — Sorting process of nanoparticles and applications of same

US 09802818	Tyler et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE) Division of Materials Research (DMR)
APPLICANT(S)	Timothy P. Tyler (Chicago, Illinois); Anne-Isabelle Henry (Chicago, Illinois); Richard P. Van Duyne (Wilmette, Illinois); Mark C. Hersam (Wilmette, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Timothy P. Tyler (Chicago, Illinois); Anne-Isabelle Henry (Chicago, Illinois); Richard P. Van Duyne (Wilmette, Illinois); Mark C. Hersam (Wilmette, Illinois)
ABSTRACT	In one aspect of the present invention, a method for sorting nanoparticles includes preparing a high-viscosity density gradient medium filled in a container, dispersing nanoparticles into an aqueous solution to form a suspension of the nanoparticles, each nanoparticle having one or more cores and a shell encapsulating the one or more cores, layering the suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container, and centrifugating the layered suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container at a predetermined speed for a predetermined period of time to form a gradient of fractions of the nanoparticles along the container, where each fraction comprises nanoparticles in a respective one of aggregation states of the nanoparticles.
FILED	Tuesday, May 01, 2012
APPL NO	13/461521
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101)
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09802873 — Methods for the production of renewable Dimethyl JP10

US 09802873	Harvey et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin G Harvey (Ridgecrest, California); Heather A Meylemans (Ridgecrest, California); Roxanne L Quintana (Ridgecrest, California)
ABSTRACT	A highly efficient method for the conversion of a natural product into the high density fuel RJ-4 with concomitant evolution of isobutylene for conversion to fuels and polymers, more specifically, embodiments of the invention relate to efficient methods for the conversion of the renewable, linear terpene alcohol, linalool into a drop-in, high density fuel suitable for ramjet or missile propulsion.
FILED	Wednesday, March 30, 2016
APPL NO	15/084592
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2265 (20130101) B01J 31/2278 (20130101) B01J 2231/20 (20130101) B01J 2531/821 (20130101) Acyclic or Carbocyclic Compounds C07C 1/20 (20130101) Original (OR) Class C07C 2/08 (20130101) C07C 2531/22 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 110/10 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 1/06 (20130101) C10L 2200/0469 (20130101) C10L 2270/04 (20130101) C10L 2270/023 (20130101)
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09802975 — Protecting groups for “Z nucleotide” and methods thereof

US 09802975	Lunstad et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Agilent Technologies, Inc. (Loveland, California)
ASSIGNEE(S)	Agilent Technologies, Inc. (Santa Clara, California)
INVENTOR(S)	Benjamin D. Lunstad (Santa Clara, California); Douglas J. Dellinger (Boulder, Colorado)
ABSTRACT	The present disclosure provides nucleoside compounds and oligonucleotides including an unnatural 6-amino-2-pyridone heterocyclic base where the 6-amino and 2-positions are protected. The 2-position of the heterocyclic base can be protected with an acyl-oxy-methyl protecting group. In some embodiments, the protected heterocyclic base has the following structure where AcOM is an acetyl-oxy-methyl group and R is a ribose or deoxyribose sugar: Methods for synthesizing an oligonucleotide are provided in which the subject compounds find use. The method can include protecting an unnatural (e.g., Z) nucleotide with an acetyl-oxy-methyl group; incorporating the protected unnatural nucleotide into a nucleotide sequence on a solid support; and removing the acetyl-oxy-methyl group from the unnatural nucleotide incorporated into the nucleotide sequence. The compounds and methods find use in the synthesis of long oligonucleotides including Z nucleotides.
FILED	Thursday, May 28, 2015
APPL NO	14/724613
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 211/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 7/06 (20130101) C07H 21/00 (20130101) C07H 23/00 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101)
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09803017 — Soluble MIC neutralizing monoclonal antibody for treating cancer

US 09803017	Wu
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
ASSIGNEE(S)	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
INVENTOR(S)	Jennifer Wu (Seattle, Washington)
ABSTRACT	Disclosed are compositions and methods relating to antibodies that bind soluble Major Histocompatibility Complex class I chain-related (sMIC). Specifically, disclosed are antibodies designed or selected to inhibit sMIC (e.g. to neutralize sMIC) shed from MIC+ tumors. Further disclosed are methods of using the antibodies for the treatment of MIC-positive cancers.
FILED	Thursday, July 03, 2014
APPL NO	14/900510
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2833 (20130101) Original (OR) Class C07K 16/2851 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/51 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/515 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2317/624 (20130101) C07K 2317/626 (20130101)
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09803231 — Macromolecule delivery to nanowells

US 09803231	Gray
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	IBIS BIOSCIENCES, INC. (Carlsbad, California)
ASSIGNEE(S)	IBIS BIOSCIENCES, INC. (Carlsbad, California)
INVENTOR(S)	Phillip N. Gray (Carlsbad, California)
ABSTRACT	Provided herein is technology relating to depositing and/or placing a macromolecule at a desired site for an assay and particularly, but not exclusively, to methods and systems for transporting a macromolecule such as a protein, a nucleic acid, or a protein:nucleic acid complex to an assay site, such as the bottom of a nanopore, a nanowell, or a zero mode waveguide.
FILED	Friday, December 28, 2012
APPL NO	14/369642
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2521/543 (20130101) C12Q 2522/101 (20130101) C12Q 2565/631 (20130101)
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09803237 — Slip-induced compartmentalization

US 09803237	Ismagilov et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	California Institute of Technology (Pasadena, California); SlipChip Corporation (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California); SlipChip Corporation (Chicago, Illinois)
INVENTOR(S)	Rustem F. Ismagilov (Altadena, California); Feng Shen (Pasadena, California)
ABSTRACT	The present invention relates to fluidic devices for compartmentalizing samples. In particular, the devices and related systems and methods allow for compartmentalization by using one or more first chambers connect by a first channel (e.g., where the cross-sectional dimension of the first channel is less than the cross-sectional dimension of at least one first chamber).
FILED	Wednesday, April 24, 2013
APPL NO	13/869856
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 7/52 (20130101) B01L 2200/0668 (20130101) B01L 2200/0673 (20130101) B01L 2300/069 (20130101) B01L 2300/161 (20130101) B01L 2300/0681 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/065 (20130101) B01L 2400/0409 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class
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09803258 — Post processing of components that are laser peened

US 09803258	Murphy
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	David S. Murphy (Southington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	David S. Murphy (Southington, Connecticut)
ABSTRACT	A method of post processing a laser peened component to remove a laser remelt layer is proposed. The post processing includes a series of steps including grit blasting, chemical etching and mechanical finishing the component. This will ensure that the mechanical property (i.e., damage tolerance) benefit of laser peening is restored to the surface of the component.
FILED	Monday, August 13, 2012
APPL NO	13/584257
ART UNIT	3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0069 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 9/00 (20130101) B23P 15/02 (20130101) Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents B24B 19/14 (20130101) Abrasive or Related Blasting With Particulate Material B24C 1/00 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 10/005 (20130101) Original (OR) Class Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/286 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49336 (20150115)
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09803265 — Metal matrix composite

US 09803265	Wood et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Contracting Command (ACC)
APPLICANT(S)	Gunite Corporation (Evansville, Indiana)
ASSIGNEE(S)	GUNITE CORPORATION (Evansville, Indiana)
INVENTOR(S)	Thomas D. Wood (Houghton, Michigan); Neil Anderson (Calumet, Michigan); Andrew Halonen (Calumet, Michigan)
ABSTRACT	The present invention relates to a metal matrix composite (MMC). The MMC includes a preform formed from a composition having ceramic particles and ceramic fibers and defining a plurality of voids. The metal matrix composite also includes a support element, such as a metal, disposed within the voids of the preform. The MMC has a wear surface defined by both the preform and the support element.
FILED	Monday, September 28, 2015
APPL NO	14/867440
ART UNIT	3657 — Material and Article Handling
CURRENT CPC	Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 11/245 (20130101) B28B 21/48 (20130101) Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 7/485 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/003 (20130101) B29C 47/0004 (20130101) B29C 47/0021 (20130101) B29C 47/0033 (20130101) B29C 47/38 (20130101) B29C 47/42 (20130101) B29C 47/0059 (20130101) B29C 47/0064 (20130101) B29C 47/402 (20130101) B29C 47/408 (20130101) B29C 47/881 (20130101) B29C 47/884 (20130101) B29C 47/8805 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/06 (20130101) B29K 2909/02 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/565 (20130101) C04B 35/632 (20130101) C04B 35/638 (20130101) C04B 35/806 (20130101) C04B 35/6263 (20130101) C04B 35/6269 (20130101) C04B 35/6316 (20130101) C04B 35/6365 (20130101) C04B 35/62204 (20130101) C04B 35/62635 (20130101) C04B 35/62655 (20130101) C04B 2235/77 (20130101) C04B 2235/526 (20130101) C04B 2235/3418 (20130101) C04B 2235/3826 (20130101) C04B 2235/5228 (20130101) C04B 2235/5248 (20130101) C04B 2235/5264 (20130101) C04B 2235/5268 (20130101) C04B 2235/5296 (20130101) C04B 2235/5436 (20130101) C04B 2235/6021 (20130101) C04B 2235/6562 (20130101) Alloys C22C 29/065 (20130101) Original (OR) Class Couplings for Transmitting Rotation; Clutches; Brakes F16D 65/125 (20130101) F16D 69/028 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 40/63 (20151101) Technical Subjects Covered by Former US Classification Y10T 428/1314 (20150115) Y10T 428/31678 (20150401)
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09803283 — Method of electroless deposition of aluminum or aluminum alloy, an electroless plating composition, and an article including the same

US 09803283	Martin et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Research, Development and Engineering Command (RDECOM)
APPLICANT(S)	HRL LABORATORIES, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	John H. Martin (Los Angeles, California); Joanna A. Kolodziejska (Arcadia, California); John J. Vajo (West Hills, California); Jason A. Graetz (Calabasas, California); Christopher S. Roper (Santa Monica, California)
ABSTRACT	A method for electroless deposition of aluminum on a substrate includes: activating the substrate; providing an aluminum ionic liquid; adding a reducing agent and an additive to the aluminum ionic liquid to form an electroless plating composition, wherein the additive may include a catalyst, an alloying element, or a combination thereof; and immersing the substrate in the electroless plating composition to have an aluminum layer deposited on the substrate. An article includes the electroless deposited aluminum layer.
FILED	Wednesday, January 29, 2014
APPL NO	14/167733
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/31 (20130101) C23C 18/1687 (20130101) Original (OR) Class
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09803485 — Turbine segmented cover plate retention method

US 09803485	Snyder
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana)
ASSIGNEE(S)	Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana)
INVENTOR(S)	Brandon R. Snyder (Indianapolis, Indiana)
ABSTRACT	An improved gas turbine cover plate assembly is disclosed for use in connection with segmented cover plates in turbine configurations where it is not possible to stagger the blades to create assembly clearance. The improved turbine assembly also avoids cover plate loading slots in the disc which can cause high stress features. The improved system also includes a method to axially retain segmented cover plates in relation to a turbine disc using a segmented retainer ring.
FILED	Wednesday, December 11, 2013
APPL NO	14/103106
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/04 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/326 (20130101) F01D 5/3015 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/60 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49321 (20150115)
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09803489 — Low loss baffled serpentine turns

US 09803489	Spangler
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
INVENTOR(S)	Brandon W. Spangler (Vernon, Connecticut)
ABSTRACT	A vane includes a forward rib and an aft rib positioned axially aft of the forward rib. The vane also includes a middle rib positioned axially between the forward rib and the aft rib, such that the forward rib and the middle rib define a forward passage configured to receive a forward baffle and the middle rib and the aft rib define an aft passage configured to receive an aft baffle. The vane also includes an inner surface extending axially from the forward rib to the aft rib, being radially separated from the middle rib via a gap such that air can flow between the aft passage and the forward passage via the gap, and having a radially outward curve from the forward rib to the middle rib and having a radially inward curve from the middle rib to the aft rib.
FILED	Friday, June 26, 2015
APPL NO	14/752143
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 5/187 (20130101) F01D 5/188 (20130101) F01D 5/189 (20130101) F01D 9/041 (20130101) Original (OR) Class F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/232 (20130101) F05D 2240/126 (20130101) F05D 2250/185 (20130101) F05D 2260/22141 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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09803500 — Gas turbine engine airfoil cooling passage configuration

US 09803500	Propheter-Hinckley et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Tracy A. Propheter-Hinckley (Manchester, Connecticut); San Quach (East Hartford, Connecticut)
ABSTRACT	An airfoil for a gas turbine engine includes an airfoil body that extends in a radial direction from a support. The airfoil body has pressure and suction side walls joined at leading and trailing edges to provide an exterior airfoil surface. A chord-wise direction extends between the leading and trailing edges and a thickness direction transverse to chord-wise direction and extending between the pressure and suction side walls. Cooling passages extend from the support into the airfoil body. The cooling passages include adjacent passageways in the thickness direction and are separated by a chord-wise wall. One of the adjacent passageways is adjacent to another passageway in the chord-wise direction and is separated by a rib in the thickness direction. The rib is discontinued at a location along the radial direction to provide an opening that fluidly connects one of the adjacent passageways to the other passageway.
FILED	Monday, April 27, 2015
APPL NO	14/696627
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/22141 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101)
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09803503 — Seal land with air injection for cavity purging

US 09803503	Lavin et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	Jeffrey R. Lavin (East Hartford, Connecticut); Michael J. Murphy (Vernon, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Jeffrey R. Lavin (East Hartford, Connecticut); Michael J. Murphy (Vernon, Connecticut)
ABSTRACT	An exhaust liner assembly including an interface between moveable parts includes a seal liner having a plurality of slots. The size of each slot varies with the circumferential position of the liner assembly to provide a stable cavity pressure within the interface to create a stable barrier about the entire circumference of the exhaust liner assembly.
FILED	Wednesday, April 04, 2012
APPL NO	13/438871
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) F01D 25/12 (20130101) F01D 25/30 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/822 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101)
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09803557 — Gas turbine engine and blocker door assembly

US 09803557	Farah et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Jorge I. Farah (Hartford, Connecticut); Donald W. Peters (Colchester, Connecticut); Adam Covino (Manchester, Connecticut); Curtis C. Cowan (E. Hampton, Connecticut); James R. Harders (Andover, Connecticut); Nicholas W. Kantany (Manchester, Connecticut)
ABSTRACT	A blocker door assembly which may be for a cooling system that may be applied to a gas turbine engine includes a plurality of blocker doors circumferentially spaced about an engine axis. Each blocker door is constructed and arranged to move in a circumferential direction to, at least in-part, control air flow through a passage in an adjacent fixture. A sync-ring is concentrically located about the engine axis, disposed in an annular first duct in direct communication with each passage, and engaged to each one of the plurality of blocker doors for simultaneous operation. The sync-ring is aero-dynamically shaped to reduce surrounding airflow resistance.
FILED	Tuesday, January 20, 2015
APPL NO	14/600951
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/105 (20130101) F01D 17/141 (20130101) F01D 17/143 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/14 (20130101) F02C 9/18 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/10 (20130101) F02K 3/075 (20130101) F02K 3/077 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/411 (20130101) F05D 2260/50 (20130101) F05D 2260/213 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101)
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09803559 — Variable vane and seal arrangement

US 09803559	Burdick et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Andrew D. Burdick (Somers, Connecticut); Thomas J. Praisner (Colchester, Connecticut); Andrew S. Aggarwala (Vernon, Connecticut); Eric A. Hudson (Harwinton, Connecticut); Michael G. McCaffrey (Windsor, Connecticut)
ABSTRACT	One exemplary embodiment of this disclosure relates to a system including an airfoil having a static portion, a moveable portion, and a seal between the static portion and the moveable portion. The seal is moveable separate from the static portion and the moveable portion.
FILED	Friday, February 06, 2015
APPL NO	14/615665
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/148 (20130101) F01D 9/02 (20130101) F01D 11/025 (20130101) F01D 17/162 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 9/20 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/122 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Y02T 50/673 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0536 (20150401)
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09803787 — Magnetically attracted fluid transfer system

US 09803787	Scott et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Gregory P. Scott (Washington, District of Columbia); Carl Glen Henshaw (Port Republic, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Gregory P. Scott (Washington, District of Columbia); Carl Glen Henshaw (Port Republic, Maryland)
ABSTRACT	A magnetic connection system with at least three components for connecting host and target systems. A first magnetic connector is attached to the host system, a second magnetic connector is attached to the target system; a third magnetic connector or puck is positioned between the first connector and the second connector. The first, second, and third connectors fit together with their magnets aligned, and the magnetic attraction is stronger between the puck and the target system connector than the puck and the host system connector. The system can transfer fuel, data, or electricity. In one example, the system transfers fuel from a fuel supply vessel to a target vessel with minimal human effort to attach the fuel connector components. The puck can have a conduit for fuel, data, or electricity that is centrally aligned with a receiving conduit in the target system connector.
FILED	Monday, September 16, 2013
APPL NO	14/028077
ART UNIT	3753 — Fluid Handling and Dispensing
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 27/34 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 37/004 (20130101) Original (OR) Class F16L 55/1015 (20130101)
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09804026 — Photoconductive emitter device with plasmonic electrodes

US 09804026	Jarrahi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) Space and Naval Warfare Systems Center (SPAWAR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Mona Jarrahi (Ann Arbor, Michigan); Christopher W. Berry (Ann Arbor, Michigan); Shang-Hua Yang (Ann Arbor, Michigan)
ABSTRACT	A photoconductive device that includes a semiconductor substrate, an antenna assembly, and a photoconductive assembly with one or more plasmonic contact electrodes. The photoconductive assembly can be provided with plasmonic contact electrodes that are arranged on the semiconductor substrate in a manner that improves the quantum efficiency of the photoconductive device by plasmonically enhancing the pump absorption into the photo-absorbing regions of semiconductor substrate. In one exemplary embodiment, the photoconductive device is arranged as a photoconductive source and is pumped at telecom pump wavelengths (e.g., 1.0-1.6 μm) and produces milliwatt-range power levels in the terahertz (THz) frequency range.
FILED	Wednesday, January 23, 2013
APPL NO	14/372779
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) H01L 31/0224 (20130101) H01L 31/02327 (20130101) H01L 31/035209 (20130101) H01L 33/04 (20130101) H01L 33/38 (20130101)
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09804072 — High temperature heating system

US 09804072	Asif et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Hysitron, Inc. (Eden Prairie, Minnesota)
ASSIGNEE(S)	Hysitron, Inc. (Eden Prairie, Minnesota)
INVENTOR(S)	Syed Amanulla Syed Asif (Bloomington, Minnesota); Edward Cyrankowski (Woodbury, Minnesota); Lucas Paul Keranen (Hutchinson, Minnesota); Ryan Major (Crystal, Minnesota); Yunje Oh (Medina, Minnesota); Oden Lee Warren (New Brighton, Minnesota); Maciej W. Misiak (Eden Prairie, Minnesota)
ABSTRACT	A heating system for use in mechanical testing at scales of microns or less includes a stage heater. The stage heater having a stage plane, and a stage heating element distributed across the stage plane. Two or more support mounts are on opposed sides of the stage plane. A first bridge extends from the stage plane to a first mount of the two or more support mounts, and a second bridge extends from the stage plane to a second mount of the two or more support mounts. The first and second bridges provide a plurality of supports between the stage plane and two or more support mounts to accordingly support the stage plane. In another example, the heating system includes a probe heater configured to heat a probe as part of mechanical testing.
FILED	Wednesday, November 28, 2012
APPL NO	14/361133
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/08 (20130101) G01N 3/18 (20130101) G01N 3/54 (20130101) Original (OR) Class G01N 2203/0078 (20130101) G01N 2203/0226 (20130101) G01N 2203/0282 (20130101) G01N 2203/0286 (20130101) G01N 2203/0482 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 1/023 (20130101) H05B 3/32 (20130101)
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09804120 — Systems and methods for multiplexed electrochemical detection

US 09804120	Kelley et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Governing Council of the University of Toronto (Toronto, Canada)
ASSIGNEE(S)	The Governing Council of the University of Toronto (Toronto, ON, Canada)
INVENTOR(S)	Shana O. Kelley (Toronto, Canada); Edward Hartley Sargent (Toronto, Canada); Brian Lam (Toronto, Canada)
ABSTRACT	Contemplated methods and devices comprise performing electrochemical sample analysis in a multiplexed electrochemical detector having reduced electrical cross-talk. The electrochemical detector includes electrodes that share a common lead from a plurality of leads. The sample, which may be a liquid sample, is introduced into one or more sample wells and a signal is applied to at least one of the electrodes. A response signal is measured while simultaneously applying a substantially fixed potential to each of a remainder of the plurality of leads.
FILED	Monday, November 30, 2015
APPL NO	14/953577
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/001 (20130101) C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 1/6876 (20130101) C12Q 2563/137 (20130101) C12Q 2565/607 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/27 (20130101) G01N 27/403 (20130101) G01N 27/416 (20130101) Original (OR) Class G01N 27/3275 (20130101) G01N 33/5438 (20130101)
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09804121 — Cephalopod proteins as proton conductors

US 09804121	Gorodetsky et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Alon Gorodetsky (Irvine, California); Long Phan (Irvine, California); Ward Walkup (Pasadena, California); David Ordinario (Irvine, California)
ABSTRACT	The disclosed invention relates to novel materials and associated methods for conducting protons, such materials comprising cephalopod proton-conducting proteins such as reflectins. The protonic conductivity of such cephalopod proton-conducting proteins may be modulated by the application of an electric field. The invention further encompasses protonic transistors comprising a cephalopod proton-conducting protein channel. The transistors and related devices of the invention are amenable to use in biological systems for the sensing or manipulation of protonic flows within the biological system.
FILED	Wednesday, December 03, 2014
APPL NO	14/559414
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4167 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0093 (20130101) H01L 51/0558 (20130101)
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09804130 — System and method for providing simulated ultrasound porosity waveforms

US 09804130	Tat et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Hong H. Tat (Redmond, Washington); Gary E. Georgeson (Tacoma, Washington); Richard H. Bossi (Renton, Washington)
ABSTRACT	A system and method is disclosed for generating ultrasound results having a simulated level of porosity for a composite. Data for a set of composite coupons having different levels of porosity is obtained. An attenuation distribution function is fit to a back wall signal generated from the data for each coupon and a library of echo patterns based on such data is created. An interpolated attenuation distribution function is calculated based on an interpolation of two stored attenuation distribution functions having the closest porosity values to the selected level. A main attenuation distribution function value is assigned to one portion of a selected region in a zero porosity coupon and attenuation distribution functions values within a predetermined percentage of the main attenuation distribution function are assigned to other portions of the region. Waveforms associated with the portions are modified based on such values and selected echo patterns from the library.
FILED	Friday, May 08, 2015
APPL NO	14/707403
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/08 (20130101) G01N 15/088 (20130101) G01N 29/11 (20130101) Original (OR) Class G01N 29/4427 (20130101) G01N 2291/015 (20130101) G01N 2291/0231 (20130101)
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09804258 — Surface non-uniformity determination with radio waves

US 09804258	Suarez
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	John Suarez (Brooklyn, New York)
ABSTRACT	Various embodiments that pertain to surface non-uniformity detection through use of radio waves are described. A vehicle can transmit radio waves to an area the vehicle is traveling to, such as a road in front of an automobile. The automobile can receive and process returned radio waves to determine if the road has a non-uniformity, such as a significant pothole or speed bump. If the road has the non-uniformity, then a driver of the automobile can be alerted so the driver can decide if evasive action should be taken and take such action if appropriate.
FILED	Friday, February 27, 2015
APPL NO	14/633814
ART UNIT	3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/412 (20130101) Original (OR) Class G01S 13/87 (20130101) G01S 13/931 (20130101) G01S 2013/9375 (20130101)
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09804600 — Systems and methods for ground plane estimation

US 09804600	Blankespoor et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Google Inc. (Mountain View, California)
ASSIGNEE(S)	Google Inc. (Mountain View, California)
INVENTOR(S)	Kevin Blankespoor (Mountain View, California); Gabriel Nelson (Mountain View, California); Neil Neville (Mountain View, California)
ABSTRACT	Example systems and methods for estimating a ground plane are provided. An example method may include determining an orientation of a body of a robotic device with respect to a gravity aligned reference frame. The method may also include determining the location of one or more contact points between the robotic device and a ground surface. The method may also include determining a ground plane estimation of the ground surface based on the determined orientation of the robotic device with respect to the gravity aligned reference frame and the determined locations of the one or more contact points. The method may also include determining a distance between the body of the robotic device and the determined ground plane estimation. The method may also include providing instructions to adjust a position and/or orientation of the robotic device based on the determined distance and the determined ground plane estimation.
FILED	Wednesday, January 06, 2016
APPL NO	14/988913
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/1615 (20130101) B25J 9/1694 (20130101) B25J 9/1697 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101)
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09804813 — Augmented reality cross-domain solution for physically disconnected security domains

US 09804813	Fugate et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Sunny James Fugate (San Diego, California); Chun-Che Peng (San Diego, California); Daniel C. Grady (San Diego, California)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Sunny James Fugate (San Diego, California); Chun-Che Peng (San Diego, California); Daniel C. Grady (San Diego, California)
ABSTRACT	A method comprising the steps of: displaying primary data having a first sensitivity level on a first display screen that is operatively coupled to a first computer; capturing an image of the first display screen with an image capture device that is operatively coupled to a second computer that is communicatively isolated from the first computer such that no data is shared between the first and second computers; executing with the second computer a display recognition and characterization algorithm to recognize the primary data based only on the captured image of the first display screen; and augmenting the primary data by displaying secondary data on a second display, wherein the secondary data is related to, and has a higher sensitivity level than, the primary data.
FILED	Wednesday, November 26, 2014
APPL NO	14/503010
ART UNIT	2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 2300/8082 (20130101) Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 2027/0138 (20130101) G02B 2027/0178 (20130101) Electric Digital Data Processing G06F 3/147 (20130101) G06F 3/1423 (20130101) Original (OR) Class G06F 21/34 (20130101) G06F 21/42 (20130101) G06F 21/602 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/001 (20130101) G09G 3/002 (20130101) G09G 3/003 (20130101) G09G 5/003 (20130101) G09G 2358/00 (20130101)
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09804849 — Space reduction in processor stressmark generation

US 09804849	Bertran et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Ramon Bertran (Bronx, New York); Pradip Bose (Yorktown Heights, New York); Alper Buyuktosunoglu (White Plains, New York); Timothy J. Slegel (Staatsburg, New York)
ABSTRACT	An aspect includes pruning a design space when generating a maximum power stressmark. A multi-stage design space search process is performed. Each stage includes calculating a number of instructions per cycle (IPC) for each instruction sequence in a set of instruction sequences that place a power stress on a system under analysis, removing one or more of the instruction sequences having an IPC lower than a pruning threshold from the set, evaluating at least one power metric of the remaining instruction sequences in the set, removing one or more of the instruction sequences having at least one power metric evaluated outside of one or more pruning ranges from the set, and passing the remaining instruction sequences in the set to a next stage. A maximum power stressmark is generated based on the evaluating of the at least one power metric from a final stage.
FILED	Tuesday, October 20, 2015
APPL NO	14/887713
ART UNIT	2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 1/28 (20130101) G06F 8/41 (20130101) G06F 9/30083 (20130101) G06F 9/30145 (20130101) Original (OR) Class G06F 9/30181 (20130101) G06F 11/36 (20130101)
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09804997 — Managing non-destructive evaluation data

US 09804997	Sharp et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Etegent Technologies, Ltd. (Cincinnati, Ohio)
ASSIGNEE(S)	Etegent Technologies, Ltd. (Cincinnati, Ohio)
INVENTOR(S)	Thomas D. Sharp (Terrace Park, Ohio); Richard A. Roth, II (Cincinnati, Ohio); Uriah M. Liggett (Independence, Kentucky); Joseph M. Kesler (Cincinnati, Ohio)
ABSTRACT	Methods manage non-destructive evaluation (“NDE”) data. NDE data for an asset is received and at least one alignment algorithm to align the NDE data to a simulated model associated therewith is determined. The NDE data is automatically aligned to the simulated model, a display representation that visually represents the aligned NDE data on the simulated model is generated, and information about the aligned NDE data is exported. Additionally, second NDE data associated with the at least a portion of the asset may also be received, at least one alignment algorithm to align the data determined, and the second NDE data aligned. Respective indications associated with the first and second NDE data may be determined and visually represented on the simulated model. Moreover, a shot descriptor file may be analyzed to determine whether additional NDE data is required to complete an alignment of NDE data.
FILED	Tuesday, June 25, 2013
APPL NO	13/926517
ART UNIT	2863 — Printing/Measuring and Testing
CURRENT CPC	Electric Digital Data Processing G06F 17/10 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 10/06 (20130101)
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09804999 — Signal/noise separation using FrFT rotational parameter obtained in relation to Wigner Distribution

US 09804999	Sud
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Seema Sud (Reston, Virginia)
ABSTRACT	A novel approach provides accurate estimation of the parameter a of a Fractional Fourier Transform (FrFT). A value of a may be selected for which the Wigner Distributions (WDs) of a signal-of-interest (SOI) and interference overlap as little as possible. However, instead of computing the WD for each signal, the FrFT may be computed for each WD, recognizing that the projection of the WD of a signal onto an axis t_ais the energy of the FrFT along the same axis. Since the technique computes a using the SOI and a measure of the interference separately, significant improvements can be made in the estimate, especially at low signal-to-noise ratio (SNR). Once the estimate is obtained, a reduced rank filter may be applied to remove the interference, since minimum mean-square error (MMSE) approaches will again fail when using the low sample support required of non-stationary environments. The technique is not only computationally more efficient than MMSE, but far more robust as well.
FILED	Wednesday, December 09, 2015
APPL NO	14/963329
ART UNIT	2182 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 17/14 (20130101) Original (OR) Class
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09805008 — System and method for encoding standard-formatted images with information

US 09805008	Sample et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	John T. Sample (Pearl River, Louisiana); Elias Z K Ioup (New Orleans, Louisiana)
ABSTRACT	System and method for displaying an encoded standard-formatted image with information including, but not limited to, geospatial information. This information, possibly in mark-up language format, can be quickly accessed and used to modify the image to which it is appended, or it can be ignored because the image itself remains unchanged.
FILED	Thursday, December 18, 2014
APPL NO	14/575766
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 17/218 (20130101) G06F 17/2247 (20130101) G06F 17/2252 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 1/32128 (20130101) H04N 19/00 (20130101) H04N 2201/3202 (20130101) H04N 2201/3216 (20130101) H04N 2201/3233 (20130101) H04N 2201/3253 (20130101)
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09805148 — Modeling and simulation analytical reply method

US 09805148	Chapman
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Michael Chapman (California, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Michael Chapman (California, Maryland)
ABSTRACT	The invention is directed to a method for discrete-event simulation, using dynamic memory in a parallel environment under Cautious Optimistic Control (COC). The method is divided into three sub-processes. The first is the pre-processing phase, which prepares the simulation for event execution. The second is the execution phase, which prepares the simulation for event execution. The third is the post-processing phase, which handles the cleanup of the simulation after the end of event execution. The invention can be integrated into various software architectures for run-time use or in post-processing analysis for data analysis in test and evaluation environments.
FILED	Monday, August 18, 2014
APPL NO	14/462080
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class
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09805227 — Subset selection of RFID tags using light

US 09805227	Hadley et al.
FUNDED BY	Department of Defense (DOD) Defense MicroElectronics Activity (DMEA)
APPLICANT(S)	Ruizhang Technology Limited Company (Shanghai, China PRC)
ASSIGNEE(S)	Ruizhang Technology Limited Company (Shanghai, China PRC)
INVENTOR(S)	Mark Alfred Hadley (Newark, California); James Harold Atherton (Morgan Hill, California); Jay Tu (Pleasanton, California); Edward John Boling (Fremont, California); John Stephen Smith (San Jose, California)
ABSTRACT	Methods and apparatuses for selecting a subset of RFID tags are provided in some embodiments. These methods and apparatuses utilize the susceptibility to light by persistent nodes found in passive tags. Light can be used to intentionally reduce persistence times in a particular subset tags or even an individual tag. Then, persistent nodes can be used as a selection criterion to distinguish previously illuminated tags from non-illuminated tags. In other embodiments, a power circuit receives a RF input source and generates a direct current (DC) output voltage. The circuit includes a bias circuit to supply a gate to source bias, which is independent of the DC output voltage. The circuit further includes a voltage multiplier circuit that is coupled to the bias circuit. The voltage multiplier circuit has MOS transistors with one transistor to receive the gate to source bias.
FILED	Thursday, July 23, 2015
APPL NO	14/807844
ART UNIT	2684 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/0008 (20130101) G06K 7/10009 (20130101) Original (OR) Class G06K 7/10079 (20130101) G06K 19/073 (20130101) G06K 19/077 (20130101) G06K 19/0701 (20130101) G06K 19/0723 (20130101) G06K 19/0728 (20130101) G06K 19/07749 (20130101) Static Stores G11C 5/145 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/217 (20130101)
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09805307 — Determining soft graph correspondence between node sets based on feature representations

US 09805307	Kang et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	U Kang (Pittsburgh, Pennsylvania); Ravindranath Konuru (Tarrytown, New York); Jimeng Sun (White Plains, New York); Hanghang Tong (Ossining, New York)
ABSTRACT	A method for determining a correspondence between a first node set of a first graph and a second node set of a second graph includes building a feature representation for each of the first graph and the second graph, and inferring the correspondence between the first node set and the second node set based on the feature representations.
FILED	Thursday, January 17, 2013
APPL NO	13/744045
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Electric Digital Data Processing G06F 17/3053 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 5/04 (20130101) Original (OR) Class
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09805311 — Event forecasting system

US 09805311	Mohler
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Multidisciplinary University Research Initiative (MURI) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Mathematical Sciences (DMS) Directorate for Social, Behavioral and Economic Sciences (SBE) Division of Behavioral and Cognitive Sciences (BCS)
APPLICANT(S)	George O. Mohler (San Jose, California)
ASSIGNEE(S)	Predpol, Inc. (Santa Cruz, California)
INVENTOR(S)	George O. Mohler (San Jose, California)
ABSTRACT	Generally provided herein is a predictive policing system including at least one crime prediction server constructed to process historical crime data to produce a crime forecast assigning at least one geographic region to at least one crime type for use in crime prevention, deterrence, and disruption practices.
FILED	Monday, February 02, 2015
APPL NO	14/612039
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 7/005 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101)
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09805718 — Clarifying natural language input using targeted questions

US 09805718	Ayan et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	SRI International (Menlo Park, California)
ASSIGNEE(S)	SRI INTERNAITONAL (Menlo Park, California)
INVENTOR(S)	Necip Fazil Ayan (Palo Alto, California); Arindam Mandal (San Mateo, California); Jing Zheng (San Jose, California)
ABSTRACT	A dialog assistant embodied in a computing system can present a clarification question based on a machine-readable version of human-generated conversational natural language input. Some versions of the dialog assistant identify a clarification target in the machine-readable version, determine a clarification type relating to the clarification target, present the clarification question in a conversational natural language manner, and process a human-generated conversational natural language response to the clarification question.
FILED	Friday, April 19, 2013
APPL NO	13/866509
ART UNIT	2658 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Electric Digital Data Processing G06F 17/2785 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/22 (20130101) Original (OR) Class G10L 15/24 (20130101) G10L 15/1815 (20130101) G10L 2015/225 (20130101) Telephonic Communication H04M 3/4936 (20130101)
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09806164 — Controlled synthesis and transfer of large area heterostructures made of bilayer and multilayer transition metal dichalocogenides

US 09806164	Terrones et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Humberto Terrones (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Ana Laura Elias (State College, Pennsylvania); Nestor Perea-Lopez (State College, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Humberto Terrones (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Ana Laura Elias (State College, Pennsylvania); Nestor Perea-Lopez (State College, Pennsylvania)
ABSTRACT	Embodiments are presented herein that provide a TMD system wherein the first layered material is made of heterobilayers or multilayers with semiconducting direct band gaps. The first layered material may be made of multiple layers of different TMD with different stackings, exhibiting smaller direct and indirect band gaps smaller than monolayer systems of TMD.
FILED	Friday, March 28, 2014
APPL NO	14/229181
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/28556 (20130101) H01L 29/45 (20130101) Original (OR) Class H01L 29/417 (20130101)
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09806208 — Method of passivating an iron disulfide surface via encapsulation in a zinc sulfide matrix

US 09806208	Frantz et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jesse A. Frantz (Washington, District of Columbia); Jason D. Myers (Alexandria, Virginia); Colin C. Baker (Alexandria, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Steven C. Erwin (Washington, District of Columbia)
ABSTRACT	A method for passivating the surface of crystalline iron disulfide (FeS₂) by encapsulating it within an epitaxial zinc sulfide (ZnS) matrix. Also disclosed is the related product comprising FeS₂encapsulated by a ZnS matrix in which the sulfur atoms at the FeS₂surfaces are passivated. Additionally disclosed is a photovoltaic (PV) device incorporating FeS₂encapsulated by a ZnS matrix.
FILED	Wednesday, June 07, 2017
APPL NO	15/615935
ART UNIT	1758 — Miscellaneous Articles, Stock Material
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0623 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) H01L 31/0368 (20130101) H01L 31/0384 (20130101) H01L 31/02167 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101)
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09806209 — Passivated iron disulfide surface encapsulated in zinc sulfide

US 09806209	Frantz et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jesse A. Frantz (Washington, District of Columbia); Jason D. Myers (Alexandria, Virginia); Colin C. Baker (Alexandria, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Steven C. Erwin (Washington, District of Columbia)
ABSTRACT	A passivated iron disulfide (FeS₂) surface encapsulated by an epitaxial zinc sulfide (ZnS) capping layer or matrix is provided. Also disclosed are methods for passivating the surface of crystalline iron disulfide by encapsulating it with an epitaxial zinc sulfide capping layer or matrix. Additionally disclosed is a photovoltaic (PV) device incorporating FeS₂encapsulated by ZnS.
FILED	Wednesday, June 07, 2017
APPL NO	15/615940
ART UNIT	1758 — Miscellaneous Articles, Stock Material
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0623 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) H01L 31/0368 (20130101) H01L 31/0384 (20130101) H01L 31/02167 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101)
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09806212 — Ultrathin group II-VI semiconductor layers, group II-VI semiconductor superlattice structures, photovoltaic devices incorporating the same, and related methods

US 09806212	Wu et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	University of Kansas (Lawrence, Kansas); Bing Li (Chengdu, China PRC); Liang-huan Feng (Chengdu, China PRC)
ASSIGNEE(S)	University of Kansas (Lawrence, Kansas)
INVENTOR(S)	Judy Z. Wu (Lawrence, Kansas); Bing Li (Chengdu, China PRC); Liang-huan Feng (Chengdu, China PRC)
ABSTRACT	Disclosed are ultrathin layers of group II-VI semiconductors, group II-VI semiconductor superlattice structures, photovoltaic devices incorporating the layers and superlattice structures and related methods. The superlattice structures comprise an ultrathin layer of a first group II-VI semiconductor alternating with an ultrathin layer of at least one additional semiconductor, e.g., a second group II-VI semiconductor, or a group IV semiconductor, or a group III-V semiconductor.
FILED	Friday, August 09, 2013
APPL NO	14/419768
ART UNIT	1757 — Miscellaneous Articles, Stock Material
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/073 (20130101) H01L 31/0296 (20130101) H01L 31/0336 (20130101) H01L 31/1828 (20130101) H01L 31/03925 (20130101) H01L 31/035236 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/543 (20130101)
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09806217 — Fully integrated CMOS-compatible photodetector with color selectivity and intrinsic gain

US 09806217	Zheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	William Marsh Rice University (Houston, Texas)
ASSIGNEE(S)	William Marsh Rice University (Houston, Texas)
INVENTOR(S)	Bob Yi Zheng (Oceanside, California); Yumin Wang (Houston, Texas); Nancy J. Halas (Houston, Texas); Peter Nordlander (Houston, Texas)
ABSTRACT	A metal-semiconductor-metal photodetecting device and method of manufacturing a metal-semiconductor-metal photodetecting device that includes a p-type silicon substrate with an oxide layer disposed on the p-type silicon substrate. Schotty junctions are disposed adjacent to the oxide layer on the p-type silicon substrate and a plasmonic grating disposed on the oxide layer. The plasmonic grating provides wavelength range selectability for the photodetecting device.
FILED	Thursday, April 30, 2015
APPL NO	14/701273
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/1085 (20130101) Original (OR) Class H01L 31/02327 (20130101)
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09806228 — Patterned layer design for group III nitride layer growth

US 09806228	Jain et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
ASSIGNEE(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
INVENTOR(S)	Rakesh Jain (Columbia, South Carolina); Wenhong Sun (Lexington, South Carolina); Jinwei Yang (Columbia, South Carolina); Maxim S. Shatalov (Columbia, South Carolina); Alexander Dobrinsky (Loudonville, New York); Michael Shur (Latham, New York); Remigijus Gaska (Columbia, South Carolina)
ABSTRACT	A device having a layer with a patterned surface for improving the growth of semiconductor layers, such as group III nitride-based semiconductor layers with a high concentration of aluminum, is provided. The patterned surface can include a substantially flat top surface and a plurality of stress reducing regions, such as openings. The substantially flat top surface can have a root mean square roughness less than approximately 0.5 nanometers, and the stress reducing regions can have a characteristic size between approximately 0.1 microns and approximately five microns and a depth of at least 0.2 microns. A layer of group-III nitride material can be grown on the first layer and have a thickness at least twice the characteristic size of the stress reducing regions.
FILED	Friday, December 23, 2016
APPL NO	15/389479
ART UNIT	2823 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0243 (20130101) H01L 21/0254 (20130101) H01L 21/0265 (20130101) H01L 21/02458 (20130101) H01L 21/02639 (20130101) H01L 29/518 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 33/06 (20130101) Original (OR) Class H01L 33/12 (20130101) H01L 33/22 (20130101) H01L 33/24 (20130101) H01L 33/32 (20130101) H01L 2933/0083 (20130101) H01L 2933/0091 (20130101)
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09806259 — Patterning devices using fluorinated compounds

US 09806259	Katz et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Howard E. Katz (Owings Mills, Maryland); Bal Mukund Dhar (Baltimore, Maryland)
ABSTRACT	A method for producing a spatially patterned structure includes forming a layer of a material on at least a portion of a substructure of the spatially patterned structure, forming a barrier layer of a fluorinated material on the layer of material to provide an intermediate structure, and exposing the intermediate structure to at least one of a second material or radiation to cause at least one of a chemical change or a structural change to at least a portion of the intermediate structure. The barrier layer substantially protects the layer of the material from chemical and structural changes during the exposing. Substructures are produced according to this method.
FILED	Tuesday, August 02, 2016
APPL NO	15/226411
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0035 (20130101) G03F 7/70058 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0014 (20130101) H01L 51/0018 (20130101) Original (OR) Class H01L 51/0023 (20130101) H01L 51/52 (20130101) H01L 51/0097 (20130101) H01L 51/102 (20130101) H01L 51/0541 (20130101) H01L 51/0545 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24479 (20150115)
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09806273 — Field effect transistor array using single wall carbon nano-tubes

US 09806273	Karna et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Shashi P. Karna (Bel Air, Maryland); Govind Mallick (Bel Air, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Shashi P. Karna (Bel Air, Maryland); Govind Mallick (Bel Air, Maryland)
ABSTRACT	A field effect transistor array comprising a substrate and a plurality of single wall carbon nano-tubes disposed on a surface of the substrate. A plurality of electrodes are disposed over the nano-tubes such that the conductive strips are spaced-apart from each other. These electrodes form the contact point for the drain and source of the field effect transistor, while one or more of the nano-carbon tubes form the channel between the source and the drain.
FILED	Monday, April 23, 2007
APPL NO	11/790052
ART UNIT	2811 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0048 (20130101) H01L 51/0545 (20130101) Original (OR) Class
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09806314 — Polymerized ionic liquid block copolymers as battery membranes

US 09806314	Elabd et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	DREXEL UNIVERSITY (Philadelphia, Pennsylvania); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Yossef A. Elabd (College Station, Texas); Karen I. Winey (Philadelphia, Pennsylvania); Yuesheng Ye (Rockville, Maryland); Jae-Hong Choi (Philadelphia, Pennsylvania); Tsen-Shan Sharon Sharick (Philadelphia, Pennsylvania)
ABSTRACT	The present invention is directed to compositions useful for use in separators for use in lithium ion batteries, and membranes, separators, and devices derived therefrom.
FILED	Tuesday, May 03, 2016
APPL NO	15/145215
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/00 (20130101) B01J 41/14 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 220/22 (20130101) C08F 220/34 (20130101) C08F 293/005 (20130101) C08F 2438/02 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2231 (20130101) C08J 2353/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) Original (OR) Class H01M 8/103 (20130101) H01M 8/1018 (20130101) H01M 8/1027 (20130101) H01M 8/1032 (20130101) H01M 8/1067 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 2008/1095 (20130101) H01M 2300/0082 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Y02E 60/521 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/70 (20130101)
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09806365 — Methods of purifying a hydrogen gas stream containing hydrogen sulfide impurities

US 09806365	Benicewicz et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Brian Benicewicz (Columbia, South Carolina); Guoqing Qian (Irmo, South Carolina)
ASSIGNEE(S)	University of South Carolina (Columbia, South Carolina)
INVENTOR(S)	Brian Benicewicz (Columbia, South Carolina); Guoqing Qian (Irmo, South Carolina)
ABSTRACT	Methods for purifying a hydrogen gas stream are provided that can include: introducing the hydrogen gas stream into the hydrogen pumping cell, and collecting a purified hydrogen gas from the hydrogen pumping cell. The hydrogen gas stream can include hydrogen sulfide in an amount of about 10 ppm to about 1,000 ppm, and can have a relative humidity of about 0.1% or more at the operational temperature and pressure of the hydrogen pumping cell.
FILED	Tuesday, September 09, 2014
APPL NO	14/481163
ART UNIT	1754 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Separation B01D 53/22 (20130101) B01D 53/326 (20130101) B01D 2255/1021 (20130101) B01D 2255/1023 (20130101) B01D 2255/1026 (20130101) B01D 2255/20753 (20130101) B01D 2256/16 (20130101) B01D 2257/11 (20130101) B01D 2257/80 (20130101) B01D 2257/102 (20130101) B01D 2257/304 (20130101) B01D 2257/406 (20130101) B01D 2257/504 (20130101) B01D 2257/7022 (20130101) B01D 2257/7025 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/503 (20130101) C01B 3/505 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/10 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0681 (20130101) Original (OR) Class Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/20 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/152 (20151101) Y02P 20/156 (20151101)
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09806420 — Near field tunable parasitic antenna

US 09806420	Church et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Justin A. Church (San Diego, California); Ricardo Santoyo-Mejia (Chula Vista, California)
ABSTRACT	An antenna comprising: a conductive ground plane; a conductive half loop grounded to the ground plane and configured to be fed with a radio frequency (RF) signal; a single, unitary, three-sided, conductive cage positioned so as to cover the half loop; and dielectric mounts disposed between the cage and the ground plane such that the cage is electrically insulated from the ground plane.
FILED	Tuesday, July 07, 2015
APPL NO	14/793526
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 5/35 (20150115) H01Q 7/005 (20130101) Original (OR) Class H01Q 21/24 (20130101)
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09806422 — Antenna-in-package structures with broadside and end-fire radiations

US 09806422	Garcia et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Alberto V. Garcia (Hartsdale, New York); Xiaoxiong Gu (White Plains, New York); Duixian Liu (Scarsdale, New York)
ABSTRACT	Package structures are provided having antenna-in-packages that are integrated with semiconductor RFIC (radio frequency integrated circuit) chips to form compact integrated radio/wireless communications systems that operate in the millimeter wave (mmWave) frequency range with radiation in broadside and end-fire directions.
FILED	Wednesday, December 10, 2014
APPL NO	14/565616
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/077 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/13 (20130101) H01L 24/16 (20130101) H01L 24/17 (20130101) H01L 24/32 (20130101) H01L 24/33 (20130101) H01L 2224/131 (20130101) H01L 2224/131 (20130101) H01L 2224/16225 (20130101) H01L 2224/16225 (20130101) H01L 2224/16227 (20130101) H01L 2224/17517 (20130101) H01L 2224/32013 (20130101) H01L 2224/32014 (20130101) H01L 2224/32225 (20130101) H01L 2224/33181 (20130101) H01L 2224/73204 (20130101) H01L 2224/73253 (20130101) H01L 2924/00012 (20130101) H01L 2924/014 (20130101) H01L 2924/15321 (20130101) H01L 2924/15322 (20130101) Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 9/0407 (20130101) Original (OR) Class H01Q 19/30 (20130101) H01Q 21/28 (20130101) H01Q 23/00 (20130101)
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09806430 — Phase-conjugate configuration of high-gain, dual-polarized sector antennas for a repeater

US 09806430	Coleman et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Research Laboratory (NRL)
APPLICANT(S)	Jeffrey O. Coleman (Kensington, Maryland); William M. Dorsey (Ellicot City, Maryland); Mark G. Parent (Port Tobacco, Maryland); Gary E. Hoover (Chantilly, Virginia); Philip G. Girardi (Reston, Virginia)
ASSIGNEE(S)	Envisioneering, Inc. (Alexandria, Virginia)
INVENTOR(S)	Jeffrey O. Coleman (Kensington, Maryland); William M. Dorsey (Ellicot City, Maryland); Mark G. Parent (Port Tobacco, Maryland); Gary E. Hoover (Chantilly, Virginia); Philip G. Girardi (Reston, Virginia)
ABSTRACT	An antenna system having a transmit assembly with a first set of antenna elements for transmitting signals. Each antenna element in this first set may be disposed from a respective adjacent antenna element by a predetermined azimuthal increment and by a predetermined altitudinal increment. The antenna system further includes a receive assembly having a second set of antenna elements for receiving signals. Each antenna element in this second set may be disposed from a respective adjacent antenna element by a predetermined azimuthal increment and by a predetermined altitudinal increment. The predetermined azimuthal and altitudinal increments of the first set may be substantially similar to the predetermined azimuthal and altitudinal increments, respectively, of the second set.
FILED	Thursday, August 09, 2012
APPL NO	13/570603
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 3/2647 (20130101) H01Q 13/02 (20130101) H01Q 13/0208 (20130101) H01Q 21/00 (20130101) Original (OR) Class H01Q 21/08 (20130101) H01Q 21/205 (20130101)
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09806485 — Photonic devices and methods of using and making photonic devices

US 09806485	Purnawirman et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Purnawirman Purnawirman (Watertown, Massachusetts); Michael R. Watts (Hinghan, Massachusetts); Ehsan Shah Hosseini (Medford, Massachusetts); Jonathan B. Bradley (Boston, Massachusetts); Jie Sun (Cambridge, Massachusetts); Matteo Cherchi (Espoo, Finland)
ASSIGNEE(S)	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambdrige, Massachusetts)
INVENTOR(S)	Purnawirman Purnawirman (Watertown, Massachusetts); Michael R. Watts (Hinghan, Massachusetts); Ehsan Shah Hosseini (Medford, Massachusetts); Jonathan B. Bradley (Boston, Massachusetts); Jie Sun (Cambridge, Massachusetts); Matteo Cherchi (Espoo, Finland)
ABSTRACT	Examples of the present invention include integrated erbium-doped waveguide lasers designed for silicon photonic systems. In some examples, these lasers include laser cavities defined by distributed Bragg reflectors (DBRs) formed in silicon nitride-based waveguides. These DBRs may include grating features defined by wafer-scale immersion lithography, with an upper layer of erbium-doped aluminum oxide deposited as the final step in the fabrication process. The resulting inverted ridge-waveguide yields high optical intensity overlap with the active medium for both the 980 nm pump (89%) and 1.5 μm laser (87%) wavelengths with a pump-laser intensity overlap of over 93%. The output powers can be 5 mW or higher and show lasing at widely-spaced wavelengths within both the C- and L-bands of the erbium gain spectrum (1536, 1561 and 1596 nm).
FILED	Wednesday, February 24, 2016
APPL NO	15/052809
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/17 (20130101) H01S 3/083 (20130101) H01S 3/091 (20130101) H01S 3/0632 (20130101) Original (OR) Class H01S 3/0635 (20130101) H01S 3/1053 (20130101) H01S 3/1608 (20130101) H01S 3/1636 (20130101) H01S 3/2308 (20130101) H01S 3/08059 (20130101) H01S 3/094096 (20130101)
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09806489 — Compact laser cavity

US 09806489	Murray
FUNDED BY	Department of Defense (DOD) Missile Defense Agency (MDA)
APPLICANT(S)	Arete Associates (Northridge, California)
ASSIGNEE(S)	Arete Associates (Northridge, California)
INVENTOR(S)	James Thomas Murray (Longmont, Colorado)
ABSTRACT	A compact laser is provided for in accordance with an exemplary embodiment in the present disclosure includes a compact resonator structure using a non-planar geometry of bulk components. The laser includes a preferred rotational direction of lasing modes and employs bulk components for establishing the preferred rotational direction of lasing modes within resonator. In some embodiments, the preferred rotational direction of lasing modes is established using a reflective element that is outside the resonator structure. In some embodiments, the reflective element induces polarization shifts in the reflected light that are compensated for by a wave plate, which may be outside the resonator structure.
FILED	Thursday, December 03, 2015
APPL NO	14/958831
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0941 (20130101) H01S 3/094084 (20130101) Original (OR) Class
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09806527 — Integrated electronics for perpetual energy harvesting

US 09806527	Olah et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Banpil Photonics, Inc. (Santa Clara, California)
ASSIGNEE(S)	Banpil Photonics, Inc. (Santa Clara, California)
INVENTOR(S)	Robert Olah (Sunnyvale, California); Achyut Kumar Dutta (Sunnyvale, California)
ABSTRACT	An apparatus for perpetually harvesting ambient near ultraviolet to far infrared radiation to provide continual power regardless of the environment, incorporating a system for the harvesting electronics governing power management, storage control, and output regulation. The harvesting electronics address issues of efficiently matching the voltage and current characteristics of the different harvested energy levels, low power consumption, and matching the power output demand. The device seeks to harvest the largely overlooked blackbody radiation through use of a thermal harvester, providing a continuous source of power, coupled with a solar harvester to provide increased power output.
FILED	Friday, June 24, 2016
APPL NO	15/192831
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Systems for Regulating Electric or Magnetic Variables G05F 1/56 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/382 (20130101) Original (OR) Class H02J 3/385 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101)
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09806639 — Dielectric fluids for linear switched capacitive devices

US 09806639	Chen et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Niskayuna, New York)
INVENTOR(S)	Qin Chen (Schenectady, New York); Manoj Ramprasad Shah (Latham, New York); Joo Han Kim (Niskayuna, New York); Stefan Grubic (Albany, New York); Nathaniel Benedict Hawes (Milton, New York)
ABSTRACT	A dielectric fluid includes a first liquid having first dielectric constant and conductivity values. The dielectric fluid also includes a second liquid having second dielectric constant and conductivity values. The first dielectric constant value is greater than the second dielectric constant value and the second electrical conductivity value is less than the first electrical conductivity value. The first and second liquids form an immiscible mixture that has third dielectric constant and conductivity values between the first and second dielectric constant values and the first and second electrical conductivity values, respectively. The first liquid forms a high conductivity phase representative of the first conductivity value, and the second liquid forms a low conductivity phase representative of the second conductivity value. The low conductivity phase is continuous the high conductivity phase is a plurality of droplets non-homogeneously dispersed within, and separated by, the continuous low conductivity phase.
FILED	Wednesday, April 29, 2015
APPL NO	14/699775
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/24 (20130101) Electric Machines Not Otherwise Provided for H02N 1/002 (20130101) Original (OR) Class
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09806678 — Bootstrap class-D wideband RF power amplifier

US 09806678	Diduck
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Eridan Communications, Inc. (San Francisco, California)
ASSIGNEE(S)	Eridan Communications, Inc. (San Francisco, California)
INVENTOR(S)	Quentin Diduck (Santa Clara, California)
ABSTRACT	A high-power, high-frequency radio frequency power amplifier includes an output stage and a single-phase driver. The output stage is arranged in a Class-D amplifier configuration and includes a first depletion mode field effect transistor (FET), a second depletion mode FET, and a bootstrap path that couples the output of the output stage to the gate of the second FET. The first and second depletion mode FETs are switched out-of-phase and between fully-ON and fully-OFF states, under the direction of the single-phase driver. The single-phase driver directly controls the ON/OFF state of the first depletion mode FET and provides a discharge path through which the input gate capacitor of the second depletion mode FET in the output stage can discharge to turn OFF the second depletion mode FET. The bootstrap path provides a current path through which the input gate capacitor of the second depletion mode FET can charge to turn the second depletion mode FET ON.
FILED	Monday, June 29, 2015
APPL NO	14/754656
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Amplifiers H03F 1/42 (20130101) Original (OR) Class H03F 1/0205 (20130101) H03F 1/0233 (20130101) H03F 3/193 (20130101) H03F 3/2173 (20130101) H03F 2200/36 (20130101) H03F 2200/351 (20130101) H03F 2200/451 (20130101)
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09806710 — Voltage-controlled magnetic-based devices having topological insulator/magnetic insulator heterostructure

US 09806710	Flatté
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
ASSIGNEE(S)	UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
INVENTOR(S)	Michael Flatté (Iowa City, Iowa)
ABSTRACT	A voltage-controlled magnetic based device is described that includes a magnetic insulator; a topological insulator adjacent the magnetic insulator; and magnetic dopants within the topological insulator. The magnetic dopants are located within an edge region of the topological insulator to inhibit charge current flow in the topological insulator during a switching operation using an applied electric field generating by applying a switching voltage across two electrodes at opposite sides of the topological insulator. Power dissipation due to carrier-based currents can be avoided or at least minimized by the magnetic dopants at the edges of the topological insulator.
FILED	Thursday, March 31, 2016
APPL NO	15/087244
ART UNIT	2898 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/04 (20130101) H01L 43/06 (20130101) H01L 43/10 (20130101) Pulse Technique H03K 17/80 (20130101) Original (OR) Class H03K 19/18 (20130101)
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09806747 — Circuits and methods for reducing interference that spectrally overlaps a desired signal based on dynamic gain control and/or equalization

US 09806747	Clark et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Christopher J. Clark (Hermosa Beach, California); Robert B. Dybdal (Palos Verdes Estates, California); Fei Wang (San Gabriel, California)
ABSTRACT	A system is provided with circuits and methods for dynamically reducing interference to maintain linear system operation and mitigate interference degradation to desired signal components. The system can include a binning subcircuit system configured to divide the digitized input signal into a plurality of spectral bins each having a power level. A power analysis subcircuit can be coupled to the binning subcircuit and configured to compare a collective power level of spectral bins to a threshold level that would produce nonlinear system operation. Based upon the collective power level exceeding the threshold level, outputting a gain control signal to a variable gain amplifier so that the system remains linear. This dynamic gain control can be applied to systems that receive and/or transmit signals. Residual interference components that degrade signal components can be dynamically removed by excision and the distortion introduced by the excision process can be reduced with equalization circuitry.
FILED	Monday, March 13, 2017
APPL NO	15/457895
ART UNIT	2631 — Digital Communications
CURRENT CPC	Transmission H04B 1/10 (20130101) Original (OR) Class H04B 1/0475 (20130101) H04B 2001/0416 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/265 (20130101)
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09807105 — Adaptive behavior profiling and anomaly scoring through continuous learning

US 09807105	Cheng et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Pau-Chen Cheng (Yorktown Heights, New York); Lawrence Koved (Pleasantville, New York); Kapil K. Singh (Cary, North Carolina)
ABSTRACT	Generating a behavior profile is provided. A newness score is calculated for a data point corresponding to a context of an access request to a resource made by a user of a client device. Newness scores for a plurality of data points corresponding to contexts of a plurality of access requests are aggregated to form an aggregated newness score. In response to determining that the aggregated newness score is greater than or equal to a pre-defined newness score threshold, data points stored in a data point cache and a long-term storage are used to generate a new behavior profile for the user or update an existing behavior profile for the user.
FILED	Wednesday, November 11, 2015
APPL NO	14/938415
ART UNIT	2436 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) Original (OR) Class H04L 67/306 (20130101) H04L 67/2842 (20130101)
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Department of Health and Human Services (HHS)

09801536 — Polarimetric accessory for colposcope

US 09801536	Gandjbakhche et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Amir Gandjbakhche (Potomac, Maryland); Victor Chernomordik (Rockville, Maryland); Moinuddin Hassan (Bristow, Virginia); Alexander Sviridov (Moscow, Russian Federation); Zachary Ulissi (Bethesda, Maryland); Paul D. Smith (Annapolis, Maryland); Albert C. Boccara (Paris, France)
ABSTRACT	A polarization-based colposcopy apparatus includes a polarization exchanging beam splitter pair oriented so that s- and p-polarizations are exchanged. An optical flux from a specimen is directed through the pair, and orthogonal components thereof are alternately or selectively coupled to an array detector. The detected images are processed based on image correlations to reveal specimen structures.
FILED	Thursday, April 04, 2013
APPL NO	14/390354
ART UNIT	2877 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/0002 (20130101) A61B 1/00009 (20130101) A61B 1/042 (20130101) A61B 1/00052 (20130101) A61B 1/00193 (20130101) A61B 1/00197 (20130101) A61B 1/303 (20130101) Original (OR) Class A61B 1/0646 (20130101)
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09801607 — Evaluating arterial pressure, vasomotor activity and their response to diagnostic tests

US 09801607	Shusterman
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Vladimir Shusterman (Pittsburgh, Pennsylvania)
ASSIGNEE(S)
INVENTOR(S)	Vladimir Shusterman (Pittsburgh, Pennsylvania)
ABSTRACT	Method and system for evaluating arterial pressure waves, vascular properties, as well as for diagnostic, physiological and pharmacological testing using various combinations of the following data acquisition and processing steps (some of the steps are optional): 1. Perturbing arterial pressure from its steady state. 2. Measuring the dynamics of at least one parameter related to the passage of arterial pressure waves along blood vessels. 3. Characterizing the magnitude and functional relation of changes in parameters described above in relation to changes in blood pressure during its displacement from and/or return to the steady state. 4. Classifying (comparing) the individual functional relation described above with a databank of parameters/functional relations for different states of vasomotor activity.
FILED	Tuesday, March 04, 2014
APPL NO	14/196738
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0456 (20130101) A61B 5/02007 (20130101) A61B 5/02014 (20130101) A61B 5/02116 (20130101) A61B 5/02125 (20130101) A61B 8/04 (20130101) Original (OR) Class
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09801829 — Methods and systems of making nanostructures

US 09801829	Guo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Peng Guo (Mountain View, California); Charles R. Marin (Gainesville, Florida); Yaping Zhao (Shanghai, China PRC); Richard N. Zare (Stanford, California)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Peng Guo (Mountain View, California); Charles R. Marin (Gainesville, Florida); Yaping Zhao (Shanghai, China PRC); Richard N. Zare (Stanford, California)
ABSTRACT	In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of making nanostructures (e.g., nanoparticles, nanofibers), systems for making nanostructures, and the like.
FILED	Friday, April 27, 2012
APPL NO	13/457609
ART UNIT	1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/70 (20130101) A61K 9/5161 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/2475 (20130101) B01J 2219/00177 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101)
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09801851 — Methods and compositions for the treatment of BCR-ABL positive lymphoblastic leukemias

US 09801851	Singh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee)
ASSIGNEE(S)	St. Jude Children's Research Hospital (Memphis, Tennessee)
INVENTOR(S)	Harpreet Singh (Memphis, Tennessee); Richard T. Williams (Newbury Park, California); Kiplin R. Guy (Memphis, Tennessee)
ABSTRACT	In one aspect, the invention relates to compositions comprising BCR-ABL tyrosine kinase inhibitors and artemisinin analogs, derivatives thereof, or related compounds, which are useful as in treating Philadelphia chromosome positive leukemias; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with BCR-ABL dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED	Thursday, May 23, 2013
APPL NO	14/403561
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) Original (OR) Class A61K 31/357 (20130101) A61K 31/366 (20130101) A61K 31/366 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09801853 — Methods for identifying and using inhibitors of casein kinase 1 epsilon isoform for inhibiting the growth and/or proliferation of MYC-driven tumor cells

US 09801853	Grandori et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Carla Grandori (Seattle, Washington); Masafumi Toyoshima (Seattle, Washington)
ASSIGNEE(S)	Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S)	Carla Grandori (Seattle, Washington); Masafumi Toyoshima (Seattle, Washington)
ABSTRACT	In one aspect, the invention provides a method for inhibiting the growth and/or proliferation of a myc-driven tumor cell comprising the step of contacting the tumor cells with a CSNK1ε inhibitor. In another aspect, the invention provides a method of treating a subject suffering from a tumor comprising myc-driven tumor cells, comprising administering to the subject an amount of a composition comprising a CSNK1ε inhibitor effective to inhibit the growth and/or proliferation of the tumor cells.
FILED	Wednesday, April 06, 2011
APPL NO	13/639258
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 33/24 (20130101)
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09801863 — Inhibitors of short-chain dehydrogenase activity for modulating hematopoietic stem cells and hematopoiesis

US 09801863	Markowitz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio); Board of Regents of the Univeristy of Texas System (Austin, Texas)
INVENTOR(S)	Sanford Markowitz (Cleveland, Ohio); Amar Desai (Cleveland, Ohio); Stanton Gerson (Cleveland, Ohio); Joseph Ready (Austin, Texas)
ABSTRACT	A method of modulating hematopoietic stem cells and hematopoiesis includes administering to a subject in need thereof a 15-PGDH inhibitor.
FILED	Wednesday, November 09, 2016
APPL NO	15/347587
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 31/4365 (20130101) Original (OR) Class A61K 38/193 (20130101)
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09801886 — Thrombocyte inhibition via vivo-morpholino knockdown of alpha IIb

US 09801886	Jagadeeswaran
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Pudur Jagadeeswaran (Denton, Texas)
ASSIGNEE(S)	University of North Texas (Denton, Texas)
INVENTOR(S)	Pudur Jagadeeswaran (Denton, Texas)
ABSTRACT	Novel compounds comprising a guanidine-rich head covalently coupled to one or more oligonucleotide antisense sequences which are useful to modulate blood coagulation by affecting the expression of integrin αIIb or β3 are described herein. This invention also includes pharmaceutical compositions containing these compounds, with or without other therapeutic agents, and to methods of using these compounds as inhibitor of platelet aggregation, as thrombolytics, and/or for the treatment of other thromboembolic disorders. Vivo-MOs, which include eight guanidine groups dendrimerically arranged in the guanidine-rich head and two synthetic antisense morpholino oligonucleotides, are representative compounds of the present invention.
FILED	Friday, January 28, 2011
APPL NO	13/015905
ART UNIT	1674 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) Original (OR) Class Heterocyclic Compounds C07D 413/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/06 (20130101)
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09801893 — Method of treatment for prostate cancer with androgen receptor antagonists and glucocorticoid receptor antagonists

US 09801893	Szmulewitz et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The University of Chicago (Chicago, Illinois)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois)
INVENTOR(S)	Russell Z. Szmulewitz (Chicago, Illinois); Suzanne D. Conzen (Park Ridge, Illinois)
ABSTRACT	Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity.
FILED	Tuesday, February 02, 2016
APPL NO	15/013660
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/567 (20130101) Original (OR) Class A61K 31/567 (20130101) A61K 31/569 (20130101) A61K 31/569 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/4166 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101)
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09801911 — Expansion of alloantigen-reactive regulatory T cells

US 09801911	Tang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Qizhi Tang (San Francisco, California); Jeffrey A. Bluestone (San Francisco, California)
ABSTRACT	The present disclosure relates generally to the manufacture of regulatory T cells (Tregs) for use in immunotherapy. In particular, the present disclosure relates to robust approaches for the expansion of alloantigen-reactive Tregs ex vivo. Alloantigen-reactive Tregs produced in this way are suitable for the induction and/or maintenance of immunologic tolerance in recipients of allogeneic transplants.
FILED	Friday, March 01, 2013
APPL NO	14/382537
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/5377 (20130101) A61K 31/5377 (20130101) A61K 35/17 (20130101) Original (OR) Class A61K 35/17 (20130101) A61K 39/001 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0635 (20130101) C12N 5/0637 (20130101) C12N 2501/04 (20130101) C12N 2501/515 (20130101) C12N 2501/2304 (20130101) C12N 2502/30 (20130101) C12N 2502/1107 (20130101)
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09801912 — ABCB5(+) stem cells for treating ocular disease

US 09801912	Frank et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	VA Boston Healthcare System (Boston, Massachusetts); Schepens Eye Research Institute (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)	VA Boston Healthcare System (Boston, Massachusetts); Schepens Eye Research Institute (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S)	Markus H. Frank (Cambridge, Massachusetts); Natasha Y. Frank (Cambridge, Massachusetts); Bruce Ksander (Boston, Massachusetts); Paraskevi Evi Kolovou (Boston, Massachusetts)
ABSTRACT	Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
FILED	Wednesday, February 19, 2014
APPL NO	14/768885
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0051 (20130101) A61K 35/30 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3834 (20130101) A61L 27/3839 (20130101) A61L 2430/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) C12N 5/0623 (20130101) C12N 5/0668 (20130101)
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09801914 — Prevotella histicola preparations and the treatment of autoimmune conditions

US 09801914	Murray et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Joseph A. Murray (Rochester, Minnesota); Eric V. Marietta (Rochester, Minnesota); Susan H. Barton (Reston, Virginia); Veena Taneja (Rochester, Minnesota); Ashutosh Mangalam (Rochester, Minnesota)
ABSTRACT	This document provides methods and materials related to Prevotella histicola preparations. For example, Prevotella histicola preparations in the form of an oral medicament or dietary supplement (e.g., a pill, tablet, capsule) are provided. In addition, methods and materials for using a Prevotella histicola preparation provided herein as an anti-inflammatory agent are provided.
FILED	Tuesday, December 20, 2016
APPL NO	15/385554
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/135 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 9/0053 (20130101) A61K 35/74 (20130101) Original (OR) Class A61K 35/741 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/01 (20130101)
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09801922 — Compositions and methods of treating cancer

US 09801922	Spitz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Douglas R. Spitz (Iowa City, Iowa); Michael K. Schultz (Iowa City, Iowa); Kyle Kloepping (Iowa City, Iowa); Yueming Zhu (Iowa City, Iowa); Nukhet Aykin-Burns (Iowa City, Iowa); Max S. Wicha (Ann Arbor, Michigan)
ASSIGNEE(S)	UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Douglas R. Spitz (Iowa City, Iowa); Michael K. Schultz (Iowa City, Iowa); Kyle Kloepping (Iowa City, Iowa); Yueming Zhu (Iowa City, Iowa); Nukhet Aykin-Burns (Iowa City, Iowa); Max S. Wicha (Ann Arbor, Michigan)
ABSTRACT	The invention provides compositions and methods to treat cancer with an agent that increases reactive oxygen species (ROS) levels in cancer cell mitochondria (“an XTPP agent”) or a pharmaceutically acceptable salt thereof, an inhibitor of hydroperoxide metabolism and a pharmaceutically acceptable diluent or carrier.
FILED	Thursday, August 02, 2012
APPL NO	14/236879
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/41 (20130101) A61K 31/341 (20130101) A61K 31/662 (20130101) A61K 31/675 (20130101) A61K 31/7004 (20130101) A61K 38/17 (20130101) Original (OR) Class A61K 45/06 (20130101)
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09801928 — Monoclonal antibodies for CSPG4 for the diagnosis and treatment of basal breast carcinoma

US 09801928	Ferrone et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Soldano Ferrone (Boston, Massachusetts); Xinhui Wang (Boston, Massachusetts)
ABSTRACT	It is disclosed herein that condroitin sulfate proteoglycan 4 (CSPG4), also known as high molecular weight melanoma associated antigen, is overexpressed on basal breast carcinoma cells (BBC), specifically triple negative basal breast carcinoma cells (TNBC). Methods for detecting basal breast cancer in a subject are disclosed. Methods are also disclosed for inhibiting the growth of a basal breast cancer cell. These methods include contacting the basal breast cancer cell with an effective amount of an antibody that specifically binds CSPG4. Additional treatment methods, and the use of antibody panels, are also described herein.
FILED	Tuesday, June 23, 2015
APPL NO	14/748123
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/3015 (20130101) C07K 16/3053 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/57415 (20130101) G01N 2333/4722 (20130101)
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09801931 — Methods and compositions based on Shiga toxin type 2 protein

US 09801931	O'Brien et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S)	The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S)	Alison D. O'Brien (Bethesda, Maryland); Angela Melton-Celsa (Sterling, Virginia); Michael Smith (Silver Spring, Maryland); James Sinclair (Baltimore, Maryland)
ABSTRACT	The invention is based on the discovery of the epitope in the Stx2 protein for the 11 E1O antibody. The invention features compositions containing non-full length Stx2 polypeptides that include the 11 E1O monoclonal antibody epitope. The invention also features methods of producing anti-Stx2 antibodies specific for the 11 E1O epitope of the Stx2 protein. Additionally, the invention features methods for treating a subject having, or at risk of developing, a Shiga toxin associated disease (e.g., hemolytic uremia syndrome and diseases associated with E. coli and S. dysenteriae infection) with a polypeptide that includes the 11 E1O epitope or with an anti-Stx2 antibody developed using the methods of the invention. Furthermore, the invention features the detection of Stx2 in a sample using the antibodies developed using the methods of the invention.
FILED	Monday, February 23, 2015
APPL NO	14/628667
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0258 (20130101) A61K 39/0283 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/25 (20130101) C07K 16/1232 (20130101) C07K 2317/34 (20130101)
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09801948 — Antimicrobial compositions and methods of use thereof

US 09801948	Altman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Yale University (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Sidney Altman (Hamden, Connecticut); Alfred Bothwell (Guilford, Connecticut); Choukri Mamoum (Farmington, Connecticut)
ABSTRACT	Antimicrobial compositions including a cell penetrating peptide (CPP) having the amino acid sequence Tyr-Ala-Arg-Val-Arg-Arg-Arg-Gly-Pro-Arg-Gly-Tyr-Ala-Arg-Val-Arg-Arg-Arg-Gly-Pro-Arg-Arg (SEQ ID NO:1) or variant thereof are disclosed. The CPP, which itself has antimicrobial properties, can be advantageously combined with or conjugated to a cargo to increase the delivery, efficacy, or combinations thereof, of the cargo into cells. In preferred embodiments, the CPP is combined with or conjugated to a functional nucleic acid, such as an external guide sequence (EGS) which can target and reduce expression of essential microbial genes or genes than impart resistance to antimicrobial drugs. Methods of using the compositions alone or in combination with traditional antimicrobial drugs to treat infections are also disclosed.
FILED	Friday, September 21, 2012
APPL NO	14/343809
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48092 (20130101) A61K 47/48246 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101)
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09801952 — Magnetic nanostructures as theranostic agents

US 09801952	Dravid
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Vinayak P. Dravid (Glenview, Illinois)
ABSTRACT	The present invention relates to magnetic nanostructures as theranostic agents, which provide dual function as diagnostic and therapeutic agents. In particular, the present invention relates to compositions comprising magnetic nanostructures and their use as targeted therapeutic agents for cancers (e.g., medulloblastoma) and Alzheimer's disease and related diseases and conditions.
FILED	Tuesday, August 04, 2015
APPL NO	14/817710
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 41/0052 (20130101) A61K 47/48623 (20130101) Original (OR) Class A61K 47/48861 (20130101) A61K 49/186 (20130101) A61K 49/1833 (20130101) A61K 49/1875 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2/004 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101)
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09801953 — Nanoparticles carrying nucleic acid cassettes for expressing RNA

US 09801953	Yang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	EMORY UNIVERSITY (Atlanta, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia)
INVENTOR(S)	Lily Yang (Atlanta, Georgia)
ABSTRACT	This disclosure relates to nanoparticles carrying nucleic acid cassettes for expressing RNA. In certain embodiments, the disclosure relates to improved methods for targeted delivery and expression of siRNAs in vivo using DNA-based siRNA-expressing nanocassettes and receptor-targeted nanoparticles. In certain embodiments, the disclosure relates to methods of targeted delivery of survivin siRNA expressing nanocassettes which enhance sensitivity of human cancer cells to anticancer agents.
FILED	Monday, October 14, 2013
APPL NO	14/052947
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/48884 (20130101) A61K 47/48892 (20130101) Original (OR) Class A61K 49/0067 (20130101) A61K 49/1866 (20130101)
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09801954 — Lipid substitution on aminoglycoside based polymers: plasmid delivery, anticancer drug delivery and transgene expression

US 09801954	Rege et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Kaushal Rege (Chandler, Arizona); Bhavani Miryala (Tempe, Arizona); Thrimoorthy Potta (Phoenix, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Kaushal Rege (Chandler, Arizona); Bhavani Miryala (Tempe, Arizona); Thrimoorthy Potta (Phoenix, Arizona)
ABSTRACT	A method to form a lipid-containing aminoglycoside-based polymer, where the method includes reacting an aminoglycoside with a diepoxide to form an aminoglycoside-based polymeric material, and then reacting the aminoglycoside-based polymeric material with an acyl chloride to form the lipid-containing aminoglycoside-based polymer.
FILED	Wednesday, November 05, 2014
APPL NO	15/034425
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/4823 (20130101) A61K 47/48046 (20130101) A61K 47/48192 (20130101) A61K 48/0041 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101)
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09802045 — Method for measuring stable and reproducible electrode-tissue impedance

US 09802045	Hines et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Amy Chu Peishuan Hines (Monterey Park, California); Dao Min Zhou (Saugus, California); Arup Roy (Valencia, California); Rongqing Dai (Valencia, California); Robert J. Greenberg (Los Angeles, California)
ASSIGNEE(S)	Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S)	Amy Chu Peishuan Hines (Monterey Park, California); Dao Min Zhou (Saugus, California); Arup Roy (Valencia, California); Rongqing Dai (Valencia, California); Robert J. Greenberg (Los Angeles, California)
ABSTRACT	The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.
FILED	Thursday, October 25, 2007
APPL NO	11/924436
ART UNIT	3766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36046 (20130101) Original (OR) Class
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09802158 — Ultrafiltration membrane device, bioartificial organ, and related methods

US 09802158	Fissell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan); The Cleveland Clinic Foundation (Cleveland, Ohio)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
INVENTOR(S)	William H. Fissell (Brecksville, Ohio); Shuvo Roy (San Francisco, California); Aaron Fleischman (Beachwood, Ohio); Kenneth G. Goldman (Olmsted Township, Ohio)
ABSTRACT	The present invention relates to ultrafiltration. In particular, the present invention provides nanoporous membranes having pores for generating in vitro and in vivo ultrafiltrate, devices and bioartificial organs utilizing such nanoporous membranes, and related methods (e.g., diagnostic methods, research methods, drug screening). The present invention further provides nanoporous membranes configured to avoid protein fouling with, for example, a polyethylene glycol surface coating.
FILED	Friday, July 29, 2016
APPL NO	15/223941
ART UNIT	1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/267 (20140204) A61M 1/1623 (20140204) Separation B01D 61/18 (20130101) B01D 61/20 (20130101) B01D 61/145 (20130101) Original (OR) Class B01D 67/0034 (20130101) B01D 67/0062 (20130101) B01D 67/0088 (20130101) B01D 2257/70 (20130101) B01D 2313/243 (20130101) B01D 2321/22 (20130101) B01D 2325/028 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 2001/4088 (20130101)
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09802888 — STAT3 inhibitors

US 09802888	Turkson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	UNIVERSITY OF HAWAII (Honolulu, Hawaii); THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Toronto, Canada)
ASSIGNEE(S)	UNIVERSITY OF HAWAII (Honolulu, Hawaii)
INVENTOR(S)	James Turkson (Honolulu, Hawaii); Patrick Gunning (Toronto, Canada); Sina Haftchenary (Toronto, Canada)
ABSTRACT	The present disclosure provides pharmaceutical compositions comprising Stat3 inhibitors and certain pharmaceutically acceptable salts thereof, and methods of use.
FILED	Friday, March 21, 2014
APPL NO	14/779276
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 311/18 (20130101) Original (OR) Class C07C 311/19 (20130101) C07C 2601/14 (20170501)
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09802904 — Inhibitors of the USP1/UAF1 deubiquitinase complex and uses thereof

US 09802904	Maloney et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); University of Delaware (Newark, Delaware)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); University of Delaware (Newark, Delaware)
INVENTOR(S)	David J. Maloney (Point of Rocks, Maryland); Andrew S. Rosenthal (Derwood, Maryland); Ajit Jadhav (Chantilly, Virginia); Thomas S. Dexheimer (Frederick, Maryland); Anton Simeonov (Bethesda, Maryland); Zhihao Zhuang (Wilmington, Delaware); Qin Liang (Elkton, Maryland); Diane K. Luci (Germantown, Maryland)
ABSTRACT	Disclosed are inhibitors of the USP1/UAF1 deubiquitinase complex, for example. of formula (I), wherein R¹, R², and Q are as defined herein, which are useful in treating diseases such as cancer, and improving the efficacy of DNA damaging agents in cancer treatment. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the invention, a method of method of inhibiting a heterodimeric deubiquitinase complex in a cell, and a method of enhancing the chemotherapeutic treatment of cancer in a mammal undergoing treatment with an anti cancer agent. Further disclosed is a method of preparing compounds of the invention.
FILED	Thursday, December 26, 2013
APPL NO	14/655538
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 239/94 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 491/048 (20130101) C07D 495/04 (20130101)
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09802924 — 5-hydroxytryptamine receptor 7 activity modulators and their method of use

US 09802924	Canney et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania)
ASSIGNEE(S)	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania)
INVENTOR(S)	Daniel J. Canney (Ambler, Pennsylvania); Benjamin E. Blass (Eagleville, Pennsylvania); Rong Gao (Eugene, Oregon); Magid Abou-Gharbia (Exton, Pennsylvania)
ABSTRACT	Pharmaceiiticai compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
FILED	Tuesday, March 11, 2014
APPL NO	14/774961
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 307/33 (20130101) C07D 307/94 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) Original (OR) Class
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09802925 — Compositions and methods for treating neurodegenerative diseases

US 09802925	Brownstein
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Azevan Pharmaceuticals, Inc. (Bethlehem, Pennsylvania)
ASSIGNEE(S)	AZEVAN PHARMACEUTICALS, INC. (Bethlehem, Pennsylvania)
INVENTOR(S)	Michael J. Brownstein (Rockville, Maryland)
ABSTRACT	Compounds, and compositions, methods, and uses thereof, are described herein for treating neurodegenerative diseases and disorders. In particular, vasopressin receptor modulators, and compositions, methods and uses thereof, are described herein for treating neuropsychiatric aspects of neurodegenerative diseases such as Huntington's Disease, Parkinson's Disease, and Alzheimer's Disease.
FILED	Friday, March 27, 2015
APPL NO	15/129190
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/422 (20130101) Heterocyclic Compounds C07D 413/04 (20130101) Original (OR) Class C07D 413/14 (20130101)
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09802948 — Inhibitors of late SV40 factor (LSF) as cancer chemotherapeutics

US 09802948	Hansen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Human Resource Development (HRD)
APPLICANT(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S)	TRUSTEES OF BOSTON UNIVERISTY (Boston, Massachusetts)
INVENTOR(S)	Ulla Hansen (Bedford, Massachusetts); Scott Schaus (Boston, Massachusetts); Trevor Grant (Vernon, Connecticut); Joshua Bishop (Belmont, Massachusetts); John Kavouris (Pittsburgh, Pennsylvania); Lisa M. Christadore (Brighton, Massachusetts)
ABSTRACT	The present invention is directed to methods, compositions and kits for treatment of cancer, e.g. heptacellular carcinoma. In some embodiments, the present invention discloses the use of a small-molecule compound of formula (I)-(XXVI) and (III′) as disclosed herein to inhibit transcription factor Late SV40 Factor (LSF) for treatment of cancer, e.g., HCC.
FILED	Friday, December 23, 2016
APPL NO	15/389564
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 215/16 (20130101) C07D 491/056 (20130101) Original (OR) Class
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09802962 — Tricyclic pyrone compounds reduce amyloid beta aggregates

US 09802962	Hua et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	AfaSci, Inc. (Redwood City, California); Kansas State University Research Foundation (Manhattan, Kansas); The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (Manhattan, Kansas); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (Oakland, California); AFASCI, INC. (Redwood City, California)
INVENTOR(S)	Duy H Hua (Manhattan, Kansas); Lee-way Jin (Davis, California); Izumi Maezawa (Sacramento, California); Xinmin Xie (Burlingame, California)
ABSTRACT	Tricyclic pyrone compounds having high oral bioavailability, excellent blood-brain barrier permeability, and low toxicity are presented. Administration of the compounds to Alzheimer's Disease transgenic models resulted in substantially reduced soluble and insoluble Aβ species in the brain without affecting general behavior and motor coordination. Furthermore, in addition to blocking the toxicity and formation of both intraneuronal and extracellular Aβ aggregates, the compounds also increase cellular cholesterol efflux, restore axonal trafficking, and enhance hippocampal synaptic plasticity.
FILED	Tuesday, September 30, 2014
APPL NO	14/503262
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 493/04 (20130101) C07D 519/00 (20130101) Original (OR) Class
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09802966 — Beta-lactamase inhibitors

US 09802966	Burns et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania)
ASSIGNEE(S)	VENATORX PHARMACEUTICALS, INC. (Malvern, Pennsylvania)
INVENTOR(S)	Christopher J. Burns (Malvern, Pennsylvania); Denis Daigle (Street, Maryland); Bin Liu (Plainsboro, New Jersey); Daniel McGarry (Malvern, Pennsylvania); Daniel C. Pevear (Downingtown, Pennsylvania); Robert E. Lee Trout (Collegeville, Pennsylvania)
ABSTRACT	Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
FILED	Monday, October 24, 2016
APPL NO	15/333049
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 45/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class
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09802967 — Polymer coated particles and methods thereof

US 09802967	Lai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Samuel K. Lai (Carrboro, North Carolina); Qi Yang (Chapel Hill, North Carolina)
ABSTRACT	Embodiments of the presently-disclosed subject matter include a composition that comprises a particle, a plurality of surface functional groups on a surface of the particle, and a plurality of coating polymers bound to the surface functional groups and forming a coating on the particle that includes a density ratio of about 0.1 to about 20.0, the density ratio being equal to a Flory radius of the plurality of coating polymers divided by a distance between adjacent surface functional groups. Embodiments of the presently-disclosed subject matter also include methods for making the present compositions as well as methods for using the present compositions to deliver a bioactive agent and treat a subject in need thereof.
FILED	Tuesday, June 17, 2014
APPL NO	14/898652
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/5146 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/02 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/025 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 112/08 (20130101)
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09802984 — Biomimetic peptide and biodegradable delivery platform for the treatment of angiogenesis- and lymphangiogenesis-dependent diseases

US 09802984	Popel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Aleksander S. Popel (Lutherville-Timonium, Maryland); Niranjan B. Pandey (White Marsh, Maryland); Esak Lee (Windsor Mill, Maryland); Jordan J. Green (Nottingham, Maryland); Ron B. Shmueli (Baltimore, Maryland)
ABSTRACT	Mimetic peptides having anti-angiogenic and anti-tumorigenic properties and methods of their use for treating cancer, ocular diseases, such as age-related macular degeneration, and other-angiogenesis-dependent diseases are disclosed. More particularly, an isolated peptide comprising the amino acid sequence LRRFSTAPFAFIDINDVINF, which exhibits anti-angiogenic activity in endothelial cell proliferation, migration, adhesion, and tube formation assays, anti-migratory activity in human breast cancer cells in vitro, anti-angiogenic and anti-tumorigenic activity in vivo in breast cancer xenograft models, and age-related macular degeneration models is disclosed. The isolate peptide also exhibits anti-lymphangiogenic and directly anti-tumorigenic properties.
FILED	Monday, June 09, 2014
APPL NO	14/896521
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) A61K 45/06 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) C12N 2510/00 (20130101)
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09802986 — Recombinant viral vectors

US 09802986	Parks et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	International AIDS Vaccine Initiative (New York, New York)
ASSIGNEE(S)	INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York)
INVENTOR(S)	Christopher L. Parks (New York, New York); Ivo Lorenz (New York, New York); Sanjay K. Phogat (New York, New York); Timothy J. Zamb (New York, New York)
ABSTRACT	The present relation relates to recombinant vesicular stomatitis virus for use as prophylactic and therapeutic vaccines for infectious diseases of AIDS. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
FILED	Thursday, December 17, 2015
APPL NO	14/972272
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16051 (20130101) C12N 2740/16134 (20130101) C12N 2760/20234 (20130101) C12N 2760/20243 (20130101) C12N 2760/20251 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 2333/162 (20130101)
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09802988 — Engineered type IV pilin of Clostridium difficile

US 09802988	Donnenberg
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	University of Maryland, Baltimore (Baltimore, Maryland)
ASSIGNEE(S)	University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S)	Michael Donnenberg (Baltimore, Maryland)
ABSTRACT	The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected with C. difficile, and vaccines comprising type IV pilin proteins, antigenic fragments and variants thereof for therapeutic interventions.
FILED	Wednesday, April 23, 2014
APPL NO	14/259413
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/08 (20130101) Peptides C07K 14/33 (20130101) Original (OR) Class C07K 16/1282 (20130101) C07K 2317/20 (20130101) C07K 2317/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/33 (20130101)
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09803006 — Targeting of herpes simplex virus to specific receptors

US 09803006	Zhou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S)	Guoying Zhou (Madison, Wisconsin); Bernard Roizman (Chicago, Illinois)
ABSTRACT	The invention relates to engineered Herpes simplex virus (HSV) particles that are targeted to one or more specific binding pair members, such as receptors. Also, recombinant vectors for producing such HSV particles are provided. By reducing the affinity of HSV for its natural receptor(s) and increasing the affinity for a selected receptor, the HSV particles of the invention are useful for targeting cells that express the selected receptor, which itself may be a product of genetic engineering. The ability to selectively target cells renders the HSV particles, particularly useful in selectively diagnosing, treating, and imaging cells bearing the selected binding pair member, such as a receptor. The invention also provides for polynucleotide-based therapy to cells bearing the selected binding pair member such as a receptor.
FILED	Monday, January 05, 2015
APPL NO	14/589581
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/2086 (20130101) A61K 47/48269 (20130101) A61K 47/48376 (20130101) A61K 47/48776 (20130101) Peptides C07K 14/5437 (20130101) C07K 16/18 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/8695 (20130101) C12N 2710/16632 (20130101) C12N 2710/16643 (20130101) C12N 2710/16645 (20130101) C12N 2799/028 (20130101) C12N 2810/50 (20130101) C12N 2810/852 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/705 (20130101)
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09803012 — Compositions and methods for regulating SAS1R

US 09803012	Herr et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) Fogarty International Center (FIC) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	John C. Herr (Charlottesville, Virginia); Monika Sachdev (Charlottesville, Virginia); Arabinda Mandal (Charlottesville, Virginia)
ASSIGNEE(S)	UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S)	John C. Herr (Charlottesville, Virginia); Monika Sachdev (Charlottesville, Virginia); Arabinda Mandal (Charlottesville, Virginia)
ABSTRACT	The present invention provides compositions and methods useful for regulating fertilization and for use as a contraceptive based on the discovery herein of an oocyte specific protein, SAS1R (Sperm Acrosomal SLLP1 Receptor), which is a sperm protein receptor. Six SAS1R variants, including the full length SAS1R, were identified. mSLLP1 and SAS1R co-localized to oocytes and to acrosomes of acrosome-reacted sperm. Interactions between mSLLP1 and SAS1R were demonstrated by far-western analysis, in a yeast two-hybrid system under stringent selection conditions, and by immunoprecipitation of SAS1R by anti-mSLLP1 as well as the converse. Purified recombinant SAS1R was found to have protease activity, to inhibit fertilization in-vitro, and to induce an immune response in females. Together, the results suggest SAS1R is a proteolytically active, oocyte and early embryo specific oolemmal metalloprotease receptor for the sperm intra-acrosomal ligand SLLP1 and is a target for regulating fertilization and as a contraceptive.
FILED	Wednesday, May 23, 2012
APPL NO	13/479167
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/4886 (20130101) A61K 39/0006 (20130101) Peptides C07K 16/28 (20130101) Original (OR) Class C07K 2316/96 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/96486 (20130101) G01N 2500/04 (20130101)
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09803017 — Soluble MIC neutralizing monoclonal antibody for treating cancer

US 09803017	Wu
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
ASSIGNEE(S)	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington)
INVENTOR(S)	Jennifer Wu (Seattle, Washington)
ABSTRACT	Disclosed are compositions and methods relating to antibodies that bind soluble Major Histocompatibility Complex class I chain-related (sMIC). Specifically, disclosed are antibodies designed or selected to inhibit sMIC (e.g. to neutralize sMIC) shed from MIC+ tumors. Further disclosed are methods of using the antibodies for the treatment of MIC-positive cancers.
FILED	Thursday, July 03, 2014
APPL NO	14/900510
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2833 (20130101) Original (OR) Class C07K 16/2851 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/51 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/515 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2317/624 (20130101) C07K 2317/626 (20130101)
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09803022 — Mesothelin domain-specific monoclonal antibodies and use thereof

US 09803022	Ho et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Mitchell Ho (Urbana, Maryland); Ira H. Pastan (Potomac, Maryland); Yen T. Phung (Annandale, Virginia); Yifan Zhang (Haymarket, Virginia); Wei Gao (Rockville, Maryland); Raffit Hassan (Gaithersburg, Maryland)
ABSTRACT	Described herein is the use of rabbit hybridoma technology, along with a panel of truncated mesothelin domain fragments, to identify anti-mesothelin mAbs that bind specific regions of mesothelin. In one aspect of the present disclosure, the rabbit mAbs bind an epitope that is not part of Region I. In particular, the identified mAbs (YP187, YP223, YP218 and YP3) bind either Region II (391-486), Region III (487-581) or a native conformation of mesothelin with subnanomolar affinity. These antibodies do not compete for binding with the mesothelin-specific immunotoxin SS1P or mesothelin-specific antibody MORAb-009. In another aspect, disclosed is a high-affinity rabbit mAb that binds Region I of mesothelin (YP158). YP158 binds native mesothelin protein in cancer cells and tissues with high affinity and specificity.
FILED	Thursday, April 28, 2016
APPL NO	15/141006
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/48484 (20130101) A61K 47/48561 (20130101) A61K 47/48569 (20130101) A61K 47/48592 (20130101) A61K 49/0058 (20130101) A61K 51/1054 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/468 (20130101) C07K 16/3023 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2317/624 (20130101) C07K 2319/30 (20130101) C07K 2319/55 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/57492 (20130101) G01N 2333/705 (20130101)
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09803047 — Alternating ring-opening metathesis polymerization

US 09803047	Sampson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI)
APPLICANT(S)	The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S)	The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S)	Nicole S. Sampson (Setauket, New York); Li Tan (Centereach, New York); Kathlyn Parker (Centereach, New York)
ABSTRACT	The invention relates to the field of polymers and olefin polymerization, and more specifically olefin metathesis polymerization. The invention provides regioregular alternating polymers and methods of synthesizing such polymers. To demonstrate, polymers were synthesized and modified with a FRET pair (Trp/Dansyl) post-polymerization.
FILED	Tuesday, February 21, 2017
APPL NO	15/438305
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/74 (20130101) A61K 31/74 (20130101) A61K 47/32 (20130101) A61K 47/48176 (20130101) A61K 47/48192 (20130101) A61K 2300/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 232/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) Original (OR) Class C08G 61/12 (20130101) C08G 61/128 (20130101) C08G 2261/74 (20130101) C08G 2261/124 (20130101) C08G 2261/126 (20130101) C08G 2261/143 (20130101) C08G 2261/145 (20130101) C08G 2261/146 (20130101) C08G 2261/148 (20130101) C08G 2261/149 (20130101) C08G 2261/226 (20130101) C08G 2261/228 (20130101) C08G 2261/418 (20130101) C08G 2261/1424 (20130101) C08G 2261/1426 (20130101) C08G 2261/1428 (20130101) C08G 2261/1432 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1637 (20130101) C09D 165/00 (20130101)
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09803187 — Baulamycins, compositions and methods of use thereof

US 09803187	Sherman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) Fogarty International Center (FIC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); Asociación Instituto Nacional de Biodiversidad (Heredia, Costa Rica)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); ASOCIACION INSTITUTO NACIONAL DE BIODIVERSIDAD (Heredia, Costa Rica)
INVENTOR(S)	David H. Sherman (Ann Arbor, Michigan); Ashootosh Tripathi (Ypsilanti, Michigan); Michael Marie Kaufman-Schofield (Ann Arbor, Michigan); Giselle Tamayo (Heredia, Costa Rica); Pam Schultz (Superior Township, Michigan)
ABSTRACT	Provided herein are compositions of compounds of formula (I), methods of inhibiting a bacterial infection by contacting a cell with a composition comprising a compound of formula (I), and methods of isolating compounds of formula (I) from an extract of Streptomyces tempisquensis.
FILED	Wednesday, May 20, 2015
APPL NO	14/717096
ART UNIT	1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) Acyclic or Carbocyclic Compounds C07C 45/79 (20130101) C07C 49/217 (20130101) C07C 49/245 (20130101) C07C 49/248 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 9/99 (20130101) Original (OR) Class
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09803189 — Virus-like platform for rapid vaccine discovery

US 09803189	Peabody et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	David S. Peabody (Albuquerque, New Mexico); Bryce Chackerian (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	David S. Peabody (Albuquerque, New Mexico); Bryce Chackerian (Albuquerque, New Mexico)
ABSTRACT	The invention is directed to virus-like particles (VLPs) of an RNA bacteriophage that (a) comprises a coat polypeptide of said phage modified by insertion of a heterologous peptide that is displayed on said VLP and (b) encapsidates said bacteriophage mRNA as well as populations of these VLPs, and their uses. The invention is further directed to VLPs that encapsidate heterologous substances, as well as populations of these VLPs and their uses.
FILED	Thursday, August 23, 2007
APPL NO	11/895198
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/5256 (20130101) A61K 2039/5258 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class C12N 2740/16122 (20130101) C12N 2795/18123 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/02 (20130101)
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09803192 — Programmable and reconfigurable microcolumn affinity chromatography device, system, and methods of use thereof

US 09803192	Craighead et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	Harold G. Craighead (Ithaca, New York); Kylan Szeto (Ithaca, New York); Sarah Reinholt (Ithaca, New York); John T. Lis (Ithaca, New York); Abdullah Ozer (Vestal, New York)
ABSTRACT	The present invention generally relates to microcolumn affinity chromatography devices, systems that include the microcolumn affinity chromatography devices of the present disclosure, methods of using the devices and the systems of the present disclosure, and methods of making the devices and the systems of the present disclosure. In certain embodiments, the microcolumn affinity chromatography device is suitable for conducting affinity chromatography in multiple microcolumns in parallel and/or in series.
FILED	Monday, October 06, 2014
APPL NO	14/507819
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Separation B01D 15/22 (20130101) B01D 15/3819 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) C12N 15/1048 (20130101) Original (OR) Class
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09803218 — Recombinant adeno-associated vectors for targeted treatment

US 09803218	Chatterjee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	CITY OF HOPE (Duarte, California)
ASSIGNEE(S)	CITY OF HOPE (Duarte, California)
INVENTOR(S)	Saswati Chatterjee (Altadena, California); Laura Jane Smith (Westford, Massachusetts); Kamehameha K. Wong, Jr. (Altadena, California)
ABSTRACT	Novel adeno-associated virus (AAV) vectors in nucleotide and amino acid forms and uses thereof are provided. The isolates show specific tropism for certain target tissues, such as blood stem cells, liver, heart and joint tissue, and may be used to transduce stem cells for introduction of genes of interest into the target tissues. Certain of the vectors are able to cross tightly controlled biological junctions, such as the blood-brain barrier, which open up additional novel uses and target organs for the vectors, providing for additional methods of gene therapy and drug delivery.
FILED	Friday, October 28, 2016
APPL NO	15/337499
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0075 (20130101) Peptides C07K 14/00 (20130101) C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2750/14122 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2810/6027 (20130101)
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09803237 — Slip-induced compartmentalization

US 09803237	Ismagilov et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	California Institute of Technology (Pasadena, California); SlipChip Corporation (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California); SlipChip Corporation (Chicago, Illinois)
INVENTOR(S)	Rustem F. Ismagilov (Altadena, California); Feng Shen (Pasadena, California)
ABSTRACT	The present invention relates to fluidic devices for compartmentalizing samples. In particular, the devices and related systems and methods allow for compartmentalization by using one or more first chambers connect by a first channel (e.g., where the cross-sectional dimension of the first channel is less than the cross-sectional dimension of at least one first chamber).
FILED	Wednesday, April 24, 2013
APPL NO	13/869856
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 7/52 (20130101) B01L 2200/0668 (20130101) B01L 2200/0673 (20130101) B01L 2300/069 (20130101) B01L 2300/161 (20130101) B01L 2300/0681 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/065 (20130101) B01L 2400/0409 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class
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09803241 — Methods and compositions for determining a graft tolerant phenotype in a subject

US 09803241	Sarwal et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Minnie M. Sarwal (Portola Valley, California); Li Li (Fremont, California)
ABSTRACT	Methods are provided for determining whether a subject has a graft tolerant phenotype. In practicing the subject methods, the expression of at least 5 genes in a sample from the subject, e.g., a blood sample, is assayed to obtain a gene expression result for the at least 5 genes. The obtained gene expression result for the at least 5 genes is then employed to determine whether the subject has a graft tolerant phenotype. Also provided are compositions, systems and kits that find use in practicing the subject methods. The methods and compositions find use in a variety of applications, including the determination of an immunosuppressive therapy regimen.
FILED	Monday, May 05, 2014
APPL NO	14/270206
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/124 (20130101) C12Q 2600/158 (20130101)
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09803243 — Biomarkers for diagnosis of stroke and its causes

US 09803243	Sharp et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) Non-Profit Organization (NPO) American Heart Association (AHA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Frank Sharp (Davis, California); Boryana Stamova (Davis, California); Glen C. Jickling (Sacramento, California)
ABSTRACT	The present invention provides compositions and methods for the diagnosis of the occurrence and cause of stroke.
FILED	Sunday, March 13, 2016
APPL NO	15/068600
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/50 (20130101) G01N 2800/2871 (20130101)
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09803244 — Methods of determining eosinophilic gastritis status based on marker or gene expression

US 09803244	Rothenberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio)
ASSIGNEE(S)	CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio)
INVENTOR(S)	Marc E. Rothenberg (Cincinnati, Ohio); Julie Caldwell (Cincinnati, Ohio)
ABSTRACT	The disclosure provides compositions and methods related to the diagnosis, prognosis, and treatment of inflammatory diseases and disorders, especially allergic inflammatory diseases and disorders.
FILED	Tuesday, April 12, 2016
APPL NO	15/096358
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 39/395 (20130101) A61K 48/00 (20130101) Peptides C07K 16/18 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/06 (20130101) G01N 2800/52 (20130101)
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09803250 — Broad range PCR-based compositions and methods for the detection and identification of fungal pathogens

US 09803250	Fredricks et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	David N. Fredricks (Seattle, Washington); Prasanna D. Khot (Mountlake Terrace, Washington); Daisy L. Ko (Seattle, Washington)
ASSIGNEE(S)	Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S)	David N. Fredricks (Seattle, Washington); Prasanna D. Khot (Mountlake Terrace, Washington); Daisy L. Ko (Seattle, Washington)
ABSTRACT	Disclosed herein are methods for detecting a fungal pathogen in a patient sample, involving isolating the sample, carrying out a PCR reaction on the sample to generate an amplicon that includes a region of the fungal 28S ribosomal RNA gene, and detecting the PCR amplicon. Also disclosed are sequences of primers for specifically detecting a broad range of fungal pathogens in the presence of human ribosomal DNA. In certain embodiments, the amplicon is detected by sequencing or by two-dimensional melt-curve analysis. In yet other embodiments, more than one fungal pathogen is detected in a sample using the methods disclosed herein.
FILED	Tuesday, November 24, 2009
APPL NO	12/625361
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6895 (20130101) Original (OR) Class C12Q 2600/156 (20130101)
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09803251 — Methods of detecting influenza virus

US 09803251	Tong
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Suxiang Tong (Duluth, Georgia)
ABSTRACT	Disclosed herein are methods of detecting influenza virus in a sample from a subject. In some embodiments, the disclosed methods include contacting a sample with at least one primer 10-40 nucleotides in length wherein the at least one primer is capable of hybridizing to an influenza virus polymerase basic protein 1 (PB1) nucleic acid at least 70% identical to the nucleic acid sequence set forth as any one of SEQ ID NOs: 1-3, amplifying the PB1 nucleic acid or a portion thereof to produce an amplified PB1 nucleic acid, and detecting the amplified PB1 nucleic acid, wherein presence of the amplified PB1 nucleic acid indicates presence of influenza virus in the sample from the subject. In some examples, the primers comprise or consist of the nucleic acid sequence set forth as one of SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 9, or SEQ ID NO: 10.
FILED	Thursday, March 07, 2013
APPL NO	14/398383
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class C12Q 2600/158 (20130101)
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09804093 — Ultrasensitive SERS flow detector

US 09804093	Schultz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	University of Notre Dame du Lac (Notre Dame, Indiana)
ASSIGNEE(S)	University of Notre Dame du Lac (South Bend, Indiana)
INVENTOR(S)	Zachary Schultz (Granger, Indiana); Oluwatosin Dada (Everett, Washington); Pierre Negri (South Bend, Indiana); Kevin Jacobs (Mishawaka, Indiana)
ABSTRACT	The invention provides an apparatus and methods for label-free, chemical specific detection in flow for high throughput characterization of analytes in applications such as flow injection analysis, electrophoresis, and chromatography. A surface-enhanced Raman scattering (SERS) flow detector capable of ultrasensitive optical detection on the millisecond time scale has been developed. The device employs hydrodynamic focusing to improve SERS detection in a flow channel where a sheath flow confines analyte molecules eluted from a capillary over a planar SERS-active substrate. Increased analyte interactions with the SERS substrate significantly improve detection sensitivity. Raman experiments at different sheath flow rates showed increased sensitivity compared with the modeling predictions, indicating increased adsorption. At low analyte concentrations, rapid analyte desorption is observed, enabling repeated and high-throughput SERS detection. The flow detector offers substantial advantages over conventional SERS-based assays such as minimal sample volumes and high detection efficiency.
FILED	Tuesday, May 26, 2015
APPL NO	14/722062
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 21/05 (20130101) G01N 21/658 (20130101) Original (OR) Class G01N 2015/0053 (20130101) G01N 2015/1006 (20130101) G01N 2015/1413 (20130101) G01N 2021/058 (20130101)
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09804160 — Protein-protein interaction as biomarkers

US 09804160	Haura
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
ASSIGNEE(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
INVENTOR(S)	Eric B. Haura (Tampa, Florida)
ABSTRACT	The subject invention pertains to materials and methods for the classification of cancers as sensitive or resistant to treatments based on protein-protein interactions, treatment of cancer, identification of biomarkers, identification of protein-protein interaction modulators, and selection of cancer treatments.
FILED	Thursday, September 27, 2012
APPL NO	14/348152
ART UNIT	1678 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) Original (OR) Class G01N 33/57407 (20130101) G01N 33/57484 (20130101) G01N 2800/52 (20130101)
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09804163 — Biomarkers for prostate cancer and methods for their detection

US 09804163	Gildersleeve et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Jeffrey Gildersleeve (Frederick, Maryland); Christopher Campbell (Baltimore, Maryland); Oyindasola Oyelaran (Boston, Massachusetts); James Gulley (Takoma Park, Maryland); Jeffrey Schlom (Potomac, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Jeffrey Gildersleeve (Frederick, Maryland); Christopher Campbell (Baltimore, Maryland); Oyindasola Oyelaran (Boston, Massachusetts); James Gulley (Takoma Park, Maryland); Jeffrey Schlom (Potomac, Maryland)
ABSTRACT	The invention provides a method for predicting the clinical response to a cancer vaccine in a patient having cancer, a method for determining the immune response to a cancer vaccine in a patient having cancer who has been administered a cancer vaccine, a method for determining the long-term survival in a patient having cancer, corresponding kits therefor, as well as methods of for improving the efficacy of a virus-based vaccine.
FILED	Friday, August 05, 2011
APPL NO	13/814337
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/585 (20130101) A61K 2039/5252 (20130101) A61K 2039/5256 (20130101) A61K 2039/55583 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24043 (20130101) C12N 2710/24143 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) Original (OR) Class G01N 33/57469 (20130101) G01N 2400/02 (20130101) G01N 2800/52 (20130101)
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09804167 — Method of overcoming therapeutic limitations of nonuniform distribution of radiopharmaceuticals and chemotherapy drugs

US 09804167	Akudugu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S)	John M. Akudugu (Bellville, South Africa); Venkata S. Neti (Lake Hiawatha, New Jersey); Roger W. Howell (Millington, New Jersey)
ABSTRACT	Disclosed is a method for predicting the optimal amounts of radiopharmaceutical and/or chemotherapy agents to administer to a patient, by determining the level of saturation of the therapeutic agents in the patient's cells. The method comprises measuring cellular incorporation of the candidate therapeutic agents in a target cell population on a cell-by-cell basis. The method is able to identify an optimal cocktail of therapeutic agents for treatment of a disease. A method of high-throughput drug discovery incorporating this method, and a 2-stage targeting method of treating a disease using this method are also disclosed.
FILED	Tuesday, October 28, 2014
APPL NO	14/526041
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 51/0402 (20130101) A61K 51/1051 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) Original (OR) Class G01N 33/5008 (20130101) G01N 33/5011 (20130101)
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09804171 — Diagnostic method for pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorder associated with streptococci infection (PANDAS)

US 09804171	Cunningham et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Moleculera Labs, Inc. (Oklahoma City, Oklahoma); The Board of Regents of the University of Oklahoma (Norman, Oklahoma); National Institutes of Health (Bethesda, Maryland)
ASSIGNEE(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma); Moleculera Labs, Inc. (Oklahoma City, Oklahoma); National Institutes of Health (Bethsesda, Maryland)
INVENTOR(S)	Phina Madeleine Cunningham (Oklahoma City, Oklahoma); Craig David Shimasaki (Edmond, Oklahoma); Susan E. Swedo (McLean, Virginia); Christine Kirvan (Lincoln, California)
ABSTRACT	The present invention provides a panel of at least five clinical analyses or tests (using serum samples) to determine the risk of pediatric acute-onset neuropsychiatric syndrome (PANS) and/or pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS) in an individual. These include enzyme linked immunosorbent assays (ELISAs) to measure antibody titers against neuronal antigens present in the brain; the neuronal antigens include lysoganglioside, tubulin, dopamine receptor D1, dopamine receptor D2, serotonin receptor 5HT2A, and serotonin receptor 5HT2C. Antibody titers against at least four of these neuronal antigens are required in the present methods; preferably antibody tiers against all of these neuronal antigens are measured. A final assay is used to quantify calcium/calmodulin-dependent protein kinase activity using a neuronal cell line. The results of these analyses or tests are then combined using an algorithm to determine whether a PANS or PANDAS diagnosis is appropriate for the individual. Depending on the diagnosis, an appropriate treatment can be determined.
FILED	Tuesday, February 16, 2016
APPL NO	15/045146
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/686 (20130101) Original (OR) Class G01N 33/6854 (20130101) G01N 33/6896 (20130101) G01N 33/56944 (20130101) G01N 2333/315 (20130101) G01N 2333/726 (20130101) G01N 2333/912 (20130101) G01N 2405/10 (20130101) G01N 2469/20 (20130101) G01N 2800/26 (20130101) G01N 2800/28 (20130101) G01N 2800/30 (20130101) G01N 2800/38 (20130101)
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09804175 — Methods and kits for diagnosing osteoarthritis and predicting progression

US 09804175	Attur et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	Mukundan Attur (Woodside, New York); Steven B. Abramson (Rye, New York)
ABSTRACT	This disclosure relates to methods and kits for diagnosing osteoarthritis and for determining the progression of osteoarthritis in a subject.
FILED	Monday, November 17, 2014
APPL NO	14/542757
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 2333/52 (20130101) G01N 2333/475 (20130101) G01N 2333/545 (20130101) G01N 2333/964 (20130101) G01N 2333/96494 (20130101) G01N 2800/56 (20130101) G01N 2800/105 (20130101)
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National Science Foundation (NSF)

09801562 — Cardiac monitoring and diagnostic systems, methods, and devices

US 09801562	Host-Madsen
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	University of Hawaii (Honolulu, Hawaii)
ASSIGNEE(S)	UNIVERSITY OF HAWAII (Honolulu, Hawaii)
INVENTOR(S)	Anders Host-Madsen (Honolulu, Hawaii)
ABSTRACT	The disclosure herein provides cardiac monitoring and diagnostic system, methods, and devices. A cardiac diagnostic system for detecting potential indicators of cardiac disease comprises: a cardiac monitoring device comprising at least one electrode configured to detect an analog electrical cardiac signal of a user; a cardiac signal filter configured to convert the analog electrical cardiac signal to digital electrocardiogram data; an atypical cardiac sequence detector configured to detect atypical cardiac patterns in the electrocardiogram data that are potentially indicative of cardiac disease; and a notification transmitter configured to generate an alert when a detected atypical cardiac pattern is determined to be indicative of cardiac disease.
FILED	Monday, June 01, 2015
APPL NO	14/727706
ART UNIT	3766 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0452 (20130101) A61B 5/04018 (20130101) Original (OR) Class A61B 5/7246 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101)
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09801772 — Human machine interfaces for lower extremity orthotics

US 09801772	Kazerooni et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Katherine Strausser (Berkeley, California); Adam Zoss (Berkeley, California); Tim Swift (Albany, California)
ASSIGNEE(S)	Ekso Bionics, Inc. (Richmond, California); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Homayoon Kazerooni (Oakland, California); Katherine Strausser (Berkeley, California); Adam Zoss (Berkeley, California); Tim Swift (Albany, California)
ABSTRACT	A system and method by which movements desired by a user of a lower extremity orthotic is determined and a control system automatically regulates the sequential operation of powered lower extremity orthotic components to enable the user, having mobility disorders, to walk, as well as perform other common mobility tasks which involve leg movements, perhaps with the use of a gait aid.
FILED	Thursday, October 06, 2011
APPL NO	13/877805
ART UNIT	3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/00 (20130101) Original (OR) Class A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 3/00 (20130101) A61H 3/02 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/1616 (20130101) A61H 2201/1642 (20130101) A61H 2201/5007 (20130101) A61H 2201/5028 (20130101) A61H 2201/5069 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2201/5092 (20130101)
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09801946 — Synthetic polyurethane composite

US 09801946	Guelcher et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Scott A. Guelcher (Thompson Station, Tennessee); Jerald Dumas (Nashville, Tennessee); Edna M. Prieto (Nashville, Tennessee); Anne Talley (Nashville, Tennessee); Andrew Harmata (Nashville, Tennessee); Katarzyna Zienkiewicz (Nashville, Tennessee)
ABSTRACT	Embodiments of the present inventions comprise composites of polyurethane(s), osteoconductive matrix, and, optionally, a growth factor. Embodiments further comprise methods of making such composite and uses thereof. The osteoconductive matrix can be a tricalcium phosphate, bioglass, or the like, and can include particles that are surface modified. Growth factors can be provided in powder form, including bone morphogenic proteins such as rhBMP-2. A composition may be moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells.
FILED	Monday, April 22, 2013
APPL NO	13/868077
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) A61K 38/1875 (20130101) A61K 47/02 (20130101) A61K 47/46 (20130101) Original (OR) Class
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09801962 — Radioactive nanoparticles and methods of making and using the same

US 09801962	Sun et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Xiankai Sun (Coppell, Texas); Yaowu Hao (Southlake, Texas); Sina Moeendarbari (Arlington, Texas)
ABSTRACT	In one aspect, radioactive nanoparticles are described herein. In some embodiments, a radioactive nanoparticle described herein comprises a metal nanoparticle core, an outer metal shell disposed over the metal nanoparticle core, and a metallic radioisotope disposed within the metal nanoparticle core or within the outer metal shell. In some cases, the radioactive nanoparticle has a size of about 30-500 nm in three dimensions. In addition, in some embodiments, the radioactive nanoparticle further comprises an inner metal shell disposed between the metal nanoparticle core and the outer metal shell. The metal nanoparticle core, outer metal shell, and inner metal shell of the radioactive nanoparticle can have various metallic compositions.
FILED	Friday, May 22, 2015
APPL NO	14/719921
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0002 (20130101) A61K 9/5115 (20130101) A61K 49/0065 (20130101) A61K 49/0093 (20130101) A61K 49/183 (20130101) A61K 51/025 (20130101) A61K 51/1251 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1014 (20130101) A61N 5/1077 (20130101) A61N 2005/1024 (20130101) A61N 2005/1089 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/02 (20130101) B01J 13/22 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/025 (20130101) B22F 9/14 (20130101) B22F 2001/0029 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 4/08 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) Y10T 428/2984 (20150115) Y10T 428/2989 (20150115)
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09802163 — Electrically conducting reverse osmosis membranes

US 09802163	Jassby et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); Duke University (Durham, North Carolina)
INVENTOR(S)	David Jassby (Riverside, California); Mark Wiesner (Raleigh, North Carolina); Charles-Francois de Lannnoy (Hamilton, Canada)
ABSTRACT	The disclosure provides composite membranes for use in water purification and filtration.
FILED	Friday, February 13, 2015
APPL NO	14/621795
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 61/025 (20130101) B01D 65/08 (20130101) B01D 67/0079 (20130101) B01D 69/02 (20130101) B01D 69/148 (20130101) B01D 71/021 (20130101) Original (OR) Class B01D 71/56 (20130101) B01D 2325/26 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/441 (20130101) C02F 2303/20 (20130101)
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09802818 — Sorting process of nanoparticles and applications of same

US 09802818	Tyler et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE) Division of Materials Research (DMR)
APPLICANT(S)	Timothy P. Tyler (Chicago, Illinois); Anne-Isabelle Henry (Chicago, Illinois); Richard P. Van Duyne (Wilmette, Illinois); Mark C. Hersam (Wilmette, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Timothy P. Tyler (Chicago, Illinois); Anne-Isabelle Henry (Chicago, Illinois); Richard P. Van Duyne (Wilmette, Illinois); Mark C. Hersam (Wilmette, Illinois)
ABSTRACT	In one aspect of the present invention, a method for sorting nanoparticles includes preparing a high-viscosity density gradient medium filled in a container, dispersing nanoparticles into an aqueous solution to form a suspension of the nanoparticles, each nanoparticle having one or more cores and a shell encapsulating the one or more cores, layering the suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container, and centrifugating the layered suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container at a predetermined speed for a predetermined period of time to form a gradient of fractions of the nanoparticles along the container, where each fraction comprises nanoparticles in a respective one of aggregation states of the nanoparticles.
FILED	Tuesday, May 01, 2012
APPL NO	13/461521
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101)
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09802948 — Inhibitors of late SV40 factor (LSF) as cancer chemotherapeutics

US 09802948	Hansen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Human Resource Development (HRD)
APPLICANT(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S)	TRUSTEES OF BOSTON UNIVERISTY (Boston, Massachusetts)
INVENTOR(S)	Ulla Hansen (Bedford, Massachusetts); Scott Schaus (Boston, Massachusetts); Trevor Grant (Vernon, Connecticut); Joshua Bishop (Belmont, Massachusetts); John Kavouris (Pittsburgh, Pennsylvania); Lisa M. Christadore (Brighton, Massachusetts)
ABSTRACT	The present invention is directed to methods, compositions and kits for treatment of cancer, e.g. heptacellular carcinoma. In some embodiments, the present invention discloses the use of a small-molecule compound of formula (I)-(XXVI) and (III′) as disclosed herein to inhibit transcription factor Late SV40 Factor (LSF) for treatment of cancer, e.g., HCC.
FILED	Friday, December 23, 2016
APPL NO	15/389564
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 215/16 (20130101) C07D 491/056 (20130101) Original (OR) Class
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09802991 — HSP20 inhibits amyloidogenesis and neurotoxicity

US 09802991	Ficht et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
ASSIGNEE(S)	THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S)	Allison Ficht (College Station, Texas); Theresa Good (Pasadena, Maryland); Kenneth Carson (San Antonio, Texas); Sungmun Lee (Seoul, South Korea)
ABSTRACT	The present inventions are compositions and methods of using at least a portion of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
FILED	Friday, March 18, 2016
APPL NO	15/073809
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/44 (20130101) Original (OR) Class C07K 14/4702 (20130101) C07K 14/4711 (20130101) C07K 2319/35 (20130101)
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09803047 — Alternating ring-opening metathesis polymerization

US 09803047	Sampson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Biological Infrastructure (DBI)
APPLICANT(S)	The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S)	The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S)	Nicole S. Sampson (Setauket, New York); Li Tan (Centereach, New York); Kathlyn Parker (Centereach, New York)
ABSTRACT	The invention relates to the field of polymers and olefin polymerization, and more specifically olefin metathesis polymerization. The invention provides regioregular alternating polymers and methods of synthesizing such polymers. To demonstrate, polymers were synthesized and modified with a FRET pair (Trp/Dansyl) post-polymerization.
FILED	Tuesday, February 21, 2017
APPL NO	15/438305
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/74 (20130101) A61K 31/74 (20130101) A61K 47/32 (20130101) A61K 47/48176 (20130101) A61K 47/48192 (20130101) A61K 2300/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 232/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) Original (OR) Class C08G 61/12 (20130101) C08G 61/128 (20130101) C08G 2261/74 (20130101) C08G 2261/124 (20130101) C08G 2261/126 (20130101) C08G 2261/143 (20130101) C08G 2261/145 (20130101) C08G 2261/146 (20130101) C08G 2261/148 (20130101) C08G 2261/149 (20130101) C08G 2261/226 (20130101) C08G 2261/228 (20130101) C08G 2261/418 (20130101) C08G 2261/1424 (20130101) C08G 2261/1426 (20130101) C08G 2261/1428 (20130101) C08G 2261/1432 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1637 (20130101) C09D 165/00 (20130101)
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09803136 — Liquid electrolyte-free, solid-state solar cells with inorganic hole transport materials

US 09803136	Kanatzidis et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Mercouri G. Kanatzidis (Wilmette, Illinois); In Chung (Evanston, Illinois); Byunghong Lee (Evanston, Illinois); Robert P. H. Chang (Glenview, Illinois)
ABSTRACT	Photovoltaic cells incorporating the compounds A/M/X compounds as hole transport materials are provide. The A/M/X compounds comprise one or more A moieties, one or more M atoms and one or more X atoms. The A moieties are selected from organic cations and elements from Group 1 of the periodic table, the M atoms are selected from elements from at least one of Groups 3, 4, 5, 13, 14 or 15 of the periodic table, and the X atoms are selected from elements from Group 17 of the periodic table.
FILED	Thursday, February 21, 2013
APPL NO	13/772794
ART UNIT	1756 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/665 (20130101) Original (OR) Class C09K 2211/10 (20130101) Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 2/00 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 9/04 (20130101) F21V 9/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) H01G 9/2059 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/542 (20130101)
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09803186 — Methyl butenol synthase

US 09803186	Gray et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS)
APPLICANT(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Dennis Gray (Bay City, Michigan); Thomas D Sharkey (East Lansing, Michigan)
ABSTRACT	The present invention provides novels genes encoding methyl butenol (MBO) synthase, methy butenol synthases and their use in methyl butenol production.
FILED	Wednesday, March 02, 2016
APPL NO	15/058746
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) C12P 7/16 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101)
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09803187 — Baulamycins, compositions and methods of use thereof

US 09803187	Sherman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) Fogarty International Center (FIC) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); Asociación Instituto Nacional de Biodiversidad (Heredia, Costa Rica)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); ASOCIACION INSTITUTO NACIONAL DE BIODIVERSIDAD (Heredia, Costa Rica)
INVENTOR(S)	David H. Sherman (Ann Arbor, Michigan); Ashootosh Tripathi (Ypsilanti, Michigan); Michael Marie Kaufman-Schofield (Ann Arbor, Michigan); Giselle Tamayo (Heredia, Costa Rica); Pam Schultz (Superior Township, Michigan)
ABSTRACT	Provided herein are compositions of compounds of formula (I), methods of inhibiting a bacterial infection by contacting a cell with a composition comprising a compound of formula (I), and methods of isolating compounds of formula (I) from an extract of Streptomyces tempisquensis.
FILED	Wednesday, May 20, 2015
APPL NO	14/717096
ART UNIT	1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) Acyclic or Carbocyclic Compounds C07C 45/79 (20130101) C07C 49/217 (20130101) C07C 49/245 (20130101) C07C 49/248 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 9/99 (20130101) Original (OR) Class
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09803292 — Barrier guided growth of microstructured and nanostructured graphene and graphite

US 09803292	Arnold et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Michael S. Arnold (Middleton, Wisconsin); Padma Gopalan (Madison, Wisconsin); Nathaniel S. Safron (Madison, Wisconsin); Myungwoong Kim (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Michael S. Arnold (Middleton, Wisconsin); Padma Gopalan (Madison, Wisconsin); Nathaniel S. Safron (Madison, Wisconsin); Myungwoong Kim (Madison, Wisconsin)
ABSTRACT	Methods for growing microstructured and nanostructured graphene by growing the microstructured and nanostructured graphene from the bottom-up directly in the desired pattern are provided. The graphene structures can be grown via chemical vapor deposition (CVD) on substrates that are partially covered by a patterned graphene growth barrier which guides the growth of the graphene.
FILED	Thursday, August 23, 2012
APPL NO	13/592564
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0453 (20130101) C01B 2204/02 (20130101) C01B 2204/04 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) Original (OR) Class C30B 29/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02425 (20130101) H01L 21/02527 (20130101) H01L 21/02642 (20130101) H01L 21/02664 (20130101) H01L 29/1606 (20130101)
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09804026 — Photoconductive emitter device with plasmonic electrodes

US 09804026	Jarrahi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) Space and Naval Warfare Systems Center (SPAWAR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Mona Jarrahi (Ann Arbor, Michigan); Christopher W. Berry (Ann Arbor, Michigan); Shang-Hua Yang (Ann Arbor, Michigan)
ABSTRACT	A photoconductive device that includes a semiconductor substrate, an antenna assembly, and a photoconductive assembly with one or more plasmonic contact electrodes. The photoconductive assembly can be provided with plasmonic contact electrodes that are arranged on the semiconductor substrate in a manner that improves the quantum efficiency of the photoconductive device by plasmonically enhancing the pump absorption into the photo-absorbing regions of semiconductor substrate. In one exemplary embodiment, the photoconductive device is arranged as a photoconductive source and is pumped at telecom pump wavelengths (e.g., 1.0-1.6 μm) and produces milliwatt-range power levels in the terahertz (THz) frequency range.
FILED	Wednesday, January 23, 2013
APPL NO	14/372779
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) H01L 31/0224 (20130101) H01L 31/02327 (20130101) H01L 31/035209 (20130101) H01L 33/04 (20130101) H01L 33/38 (20130101)
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09804331 — Pre-assembled whispering gallery mode resonance sensors, for use as dip sensors or vapor sensors, for example, and methods for making such sensors

US 09804331	Agarwal et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Monica Agarwal (Troy, New York); Natalie Huiyi Luo (Brooklyn, New York); Iwao Teraoka (Rye, New York)
ASSIGNEE(S)	NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S)	Monica Agarwal (Troy, New York); Natalie Huiyi Luo (Brooklyn, New York); Iwao Teraoka (Rye, New York)
ABSTRACT	A robust sensor, suitable for dipping into fluid wells, includes (a) a stem; (b) a whispering gallery mode (“WGM”) resonator mechanically supported by the stem; and (c) feed and pickup optical fibers optically coupled with the WGM resonator and mechanically coupled with the stem, thereby defining a stem-resonator-fiber assembly, wherein a portion of the stem-resonator-fiber assembly including the WGM resonator can fit within an imaginary cylinder having a diameter of 7 mm (or 2 mm, or even 1 mm). Such a whispering gallery mode (“WGM”) dip sensor, including (1) a stem, (2) a WGM resonator, and (3) feed and pickup optical fibers, may be made by (a) fabricating the WGM resonator and the stem from an optical fiber; (b) fabricating tapers on the feed and pickup fibers; (c) positioning tapers of the feed and pickup fibers relative to the WGM resonator such that an optical coupling between the tapers and the WGM resonator is established; and (d) mechanically coupling the stem with the feed and pickup fibers.
FILED	Tuesday, August 11, 2015
APPL NO	14/823840
ART UNIT	2874 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/7746 (20130101) Optical Elements, Systems, or Apparatus G02B 6/29341 (20130101) Original (OR) Class
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09804423 — On-chip optical polarization controller

US 09804423	Reano et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
ASSIGNEE(S)	Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S)	Ronald M. Reano (Columbus, Ohio); Peng Sun (Carlsbad, California); Qiang Xu (Columbus, Ohio)
ABSTRACT	An example optical polarization controller can include a substantially planar substrate and a waveguide unit cell formed on the substantially planar substrate. The waveguide unit cell can include a first out-of-plane waveguide portion and a second out-of-plane waveguide portion coupled to the first out-of-plane waveguide portion. Each of the first and second out-of-plane waveguide portions can respectively include a core material layer arranged between a first optical cladding layer having a first stress-response property and a second optical cladding layer having a second stress-response property. The first and second stress-response properties can be different such that each of the first and second out-of-plane waveguide portions is deflected by a deflection angle.
FILED	Monday, February 24, 2014
APPL NO	14/770291
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/126 (20130101) G02B 6/136 (20130101) G02B 6/2934 (20130101) G02B 6/3504 (20130101) G02B 6/3596 (20130101) G02B 6/12002 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0136 (20130101) Original (OR) Class G02F 1/0147 (20130101) G02F 2201/06 (20130101) G02F 2202/10 (20130101)
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09804494 — Method for creating topographical patterns in polymers via surface energy patterned films and the marangoni effect

US 09804494	Ellison et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Christopher J. Ellison (Austin, Texas); Joshua M. Katzenstein (Austin, Texas); Dustin W. Janes (Austin, Texas)
ABSTRACT	Using a broadband light source and a photomask, surface energy gradients can be directly transferred into polymer films. The Marangoni effect causes high surface energy regions to rise upon heating the film. This leads to the formation of three-dimensional topography that can be locked in by quenching the polymer by cooling.
FILED	Thursday, August 15, 2013
APPL NO	13/967814
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/02 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/26 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/24802 (20150115)
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09804724 — Haptic device with indirect haptic feedback

US 09804724	Colgate et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	James Edward Colgate (Evanston, Illinois); Michael A. Peshkin (Evanston, Illinois); John Glassmire (Seattle, Washington); Laura Winfield Alexander (Sunbury, Ohio)
ABSTRACT	An indirect haptic device having a substrate having a touch surface, a position sensor of a user's clothed appendage relative to the touch surface, a friction modulator associated with the substrate, a control device connected to the position sensor and the friction modulator, wherein a coefficient of friction on the touch surface is modulated in response to a sensed position of a user's clothed appendage relative to the touch surface and/or a derivative thereof.
FILED	Thursday, August 06, 2015
APPL NO	14/820191
ART UNIT	2696 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/016 (20130101) G06F 3/041 (20130101) G06F 3/045 (20130101) Original (OR) Class G06F 3/0362 (20130101) G06F 3/0414 (20130101) G06F 3/0421 (20130101) G06F 2203/04104 (20130101)
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09805170 — System and methods for performing medical physics calculations

US 09805170	Keyes et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Roy William Keyes (Albuquerque, New Mexico); Christian Romano (Albuquerque, New Mexico); Shuang Luan (Albuquerque, New Mexico); Dorian C. Arnold (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Roy William Keyes (Albuquerque, New Mexico); Christian Romano (Albuquerque, New Mexico); Shuang Luan (Albuquerque, New Mexico); Dorian C. Arnold (Albuquerque, New Mexico)
ABSTRACT	A method of calculating radiation fluence and energy deposition distributions on a networked virtual computational cluster is presented. With this method, complex Monte Carlo simulations that require expansive equipment, personnel, and financial resources can be done efficiently and inexpensively by hospitals and clinics requiring radiation therapy dose calculations.
FILED	Thursday, April 28, 2011
APPL NO	13/643844
ART UNIT	2454 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 9/5083 (20130101) G06F 19/3437 (20130101) G06F 19/3481 (20130101) Original (OR) Class
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09805268 — System and method for processing a video stream to extract highlights

US 09805268	Xing et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Eric Xing (Pittsburgh, Pennsylvania); Bin Zhao (Pittsburgh, Pennsylvania)
ABSTRACT	With the widespread availability of video cameras, we are facing an ever-growing enormous collection of unedited and unstructured video data. Due to lack of an automatic way to generate highlights from this large collection of video streams, these videos can be tedious and time consuming to index or search. The present invention is a novel method of online video highlighting, a principled way of generating a short video highlight summarizing the most important and interesting contents of a potentially very long video, which is costly both time-wise and financially for manual processing. Specifically, the method learns a dictionary from given video using group sparse coding, and updates atoms in the dictionary on-the-fly. A highlight of the given video is then generated by combining segments that cannot be sparsely reconstructed using the learned dictionary. The online fashion of the method enables it to process arbitrarily long videos and starts generating highlights before seeing the end of the video, both attractive characteristics for practical applications.
FILED	Tuesday, July 14, 2015
APPL NO	14/798657
ART UNIT	2484 — Recording and Compression
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00718 (20130101) G06K 9/00751 (20130101) Original (OR) Class G06K 9/00765 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 27/02 (20130101) G11B 27/22 (20130101) G11B 27/3081 (20130101)
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09805311 — Event forecasting system

US 09805311	Mohler
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Multidisciplinary University Research Initiative (MURI) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Mathematical Sciences (DMS) Directorate for Social, Behavioral and Economic Sciences (SBE) Division of Behavioral and Cognitive Sciences (BCS)
APPLICANT(S)	George O. Mohler (San Jose, California)
ASSIGNEE(S)	Predpol, Inc. (Santa Cruz, California)
INVENTOR(S)	George O. Mohler (San Jose, California)
ABSTRACT	Generally provided herein is a predictive policing system including at least one crime prediction server constructed to process historical crime data to produce a crime forecast assigning at least one geographic region to at least one crime type for use in crime prevention, deterrence, and disruption practices.
FILED	Monday, February 02, 2015
APPL NO	14/612039
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 7/005 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101)
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09805705 — Multi-touch piano keyboard

US 09805705	McPherson et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Andrew McPherson (London, United Kingdom); Youngmoo Kim (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Andrew McPherson (London, United Kingdom); Youngmoo Kim (Philadelphia, Pennsylvania)
ABSTRACT	A musical keyboard touch sensor pad having a plurality of integrated sensors disposed in an array is disclosed. The plurality of integrated sensors represents a keyboard key. A processor is electronically coupled to the plurality of integrated sensors. The processor is programmed to receive signals from several of the plurality of integrated sensors and to generate a sound signal based on input from the several of the plurality of integrated sensors. The output is variable based on the number in the plurality and the location of the plurality in the array. An audio output device is electronically coupled to the processor to generate a sound based on the sound signal. A keyboard using a plurality of the sensor pads as well as a method of generating sounds from the keyboard are also disclosed.
FILED	Monday, April 25, 2016
APPL NO	15/137017
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/044 (20130101) G06F 2203/04104 (20130101) Electrophonic Musical Instruments G10H 1/02 (20130101) G10H 1/344 (20130101) G10H 7/06 (20130101) Original (OR) Class G10H 2220/221 (20130101) G10H 2220/275 (20130101)
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09805921 — Ambient infrared laser ablation mass spectrometry (AIRLAB-MS) with plume capture by continuous flow solvent probe

US 09805921	O'Brien et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Jeremy T. O'Brien (Cambridge, Massachusetts); Evan R. Williams (Oakland, California); Hoi-Ying N. Holman (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Jeremy T. O'Brien (Cambridge, Massachusetts); Evan R. Williams (Oakland, California); Hoi-Ying N. Holman (Oakland, California)
ABSTRACT	A new experimental setup for spatially resolved ambient infrared laser ablation mass spectrometry (AIRLAB-MS) that uses an infrared microscope with an infinity-corrected reflective objective and a continuous flow solvent probe coupled to a Fourier transform ion cyclotron resonance mass spectrometer is described. The efficiency of material transfer from the sample to the electrospray ionization emitter was determined using glycerol/methanol droplets containing 1 mM nicotine and is ˜50%. This transfer efficiency is significantly higher than values reported for similar techniques.
FILED	Monday, June 15, 2015
APPL NO	14/740176
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/167 (20130101) H01J 49/0463 (20130101) Original (OR) Class
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09806164 — Controlled synthesis and transfer of large area heterostructures made of bilayer and multilayer transition metal dichalocogenides

US 09806164	Terrones et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Humberto Terrones (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Ana Laura Elias (State College, Pennsylvania); Nestor Perea-Lopez (State College, Pennsylvania)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Humberto Terrones (State College, Pennsylvania); Mauricio Terrones (State College, Pennsylvania); Ana Laura Elias (State College, Pennsylvania); Nestor Perea-Lopez (State College, Pennsylvania)
ABSTRACT	Embodiments are presented herein that provide a TMD system wherein the first layered material is made of heterobilayers or multilayers with semiconducting direct band gaps. The first layered material may be made of multiple layers of different TMD with different stackings, exhibiting smaller direct and indirect band gaps smaller than monolayer systems of TMD.
FILED	Friday, March 28, 2014
APPL NO	14/229181
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/28556 (20130101) H01L 29/45 (20130101) Original (OR) Class H01L 29/417 (20130101)
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09806212 — Ultrathin group II-VI semiconductor layers, group II-VI semiconductor superlattice structures, photovoltaic devices incorporating the same, and related methods

US 09806212	Wu et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	University of Kansas (Lawrence, Kansas); Bing Li (Chengdu, China PRC); Liang-huan Feng (Chengdu, China PRC)
ASSIGNEE(S)	University of Kansas (Lawrence, Kansas)
INVENTOR(S)	Judy Z. Wu (Lawrence, Kansas); Bing Li (Chengdu, China PRC); Liang-huan Feng (Chengdu, China PRC)
ABSTRACT	Disclosed are ultrathin layers of group II-VI semiconductors, group II-VI semiconductor superlattice structures, photovoltaic devices incorporating the layers and superlattice structures and related methods. The superlattice structures comprise an ultrathin layer of a first group II-VI semiconductor alternating with an ultrathin layer of at least one additional semiconductor, e.g., a second group II-VI semiconductor, or a group IV semiconductor, or a group III-V semiconductor.
FILED	Friday, August 09, 2013
APPL NO	14/419768
ART UNIT	1757 — Miscellaneous Articles, Stock Material
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/073 (20130101) H01L 31/0296 (20130101) H01L 31/0336 (20130101) H01L 31/1828 (20130101) H01L 31/03925 (20130101) H01L 31/035236 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/543 (20130101)
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09806226 — Deep ultraviolet light emitting diode

US 09806226	Gaska et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
ASSIGNEE(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
INVENTOR(S)	Remigijus Gaska (Columbia, South Carolina); Maxim S. Shatalov (Columbia, South Carolina); Michael Shur (Latham, New York); Alexander Dobrinsky (Loudonville, New York)
ABSTRACT	A method of fabricating a light emitting diode, which includes an n-type contact layer and a light generating structure adjacent to the n-type contact layer, is provided. The light generating structure includes a set of quantum wells. The contact layer and light generating structure can be configured so that a difference between an energy of the n-type contact layer and an electron ground state energy of a quantum well is greater than an energy of a polar optical phonon in a material of the light generating structure. Additionally, the light generating structure can be configured so that its width is comparable to a mean free path for emission of a polar optical phonon by an electron injected into the light generating structure.
FILED	Tuesday, September 06, 2016
APPL NO	15/257316
ART UNIT	2822 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/04 (20130101) H01L 33/06 (20130101) Original (OR) Class H01L 33/10 (20130101) H01L 33/22 (20130101) H01L 33/0025 (20130101) H01L 33/32 (20130101) H01L 33/38 (20130101) H01L 33/46 (20130101) H01L 33/0075 (20130101) H01L 33/145 (20130101) H01L 33/385 (20130101) H01L 33/405 (20130101) H01L 2933/0058 (20130101)
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09807287 — Variable imaging arrangements and methods therefor

US 09807287	Ng et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S)	Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Yi-Ren Ng (Stanford, California); Patrick M. Hanrahan (Portola Valley, California); Mark A. Horowitz (Menlo Park, California); Marc S. Levoy (Stanford, California)
ABSTRACT	Various approaches to imaging involve selecting directional and spatial resolution. According to an example embodiment, images are computed using an imaging arrangement to facilitate selective directional and spatial aspects of the detection and processing of light data. Light passed through a main lens is directed to photosensors via a plurality of microlenses. The separation between the microlenses and photosensors is set to facilitate directional and/or spatial resolution in recorded light data, and facilitating refocusing power and/or image resolution in images computed from the recorded light data. In one implementation, the separation is varied between zero and one focal length of the microlenses to respectively facilitate spatial and directional resolution (with increasing directional resolution, hence refocusing power, as the separation approaches one focal length).
FILED	Tuesday, June 30, 2015
APPL NO	14/755720
ART UNIT	2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 3/0056 (20130101) G02B 27/0075 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14627 (20130101) Pictorial Communication, e.g Television H04N 5/2173 (20130101) H04N 5/2254 (20130101) Original (OR) Class H04N 5/23212 (20130101) H04N 5/23232 (20130101) H04N 5/23293 (20130101) H04N 13/0235 (20130101)
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Department of Energy (DOE)

09802818 — Sorting process of nanoparticles and applications of same

US 09802818	Tyler et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE) Division of Materials Research (DMR)
APPLICANT(S)	Timothy P. Tyler (Chicago, Illinois); Anne-Isabelle Henry (Chicago, Illinois); Richard P. Van Duyne (Wilmette, Illinois); Mark C. Hersam (Wilmette, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Timothy P. Tyler (Chicago, Illinois); Anne-Isabelle Henry (Chicago, Illinois); Richard P. Van Duyne (Wilmette, Illinois); Mark C. Hersam (Wilmette, Illinois)
ABSTRACT	In one aspect of the present invention, a method for sorting nanoparticles includes preparing a high-viscosity density gradient medium filled in a container, dispersing nanoparticles into an aqueous solution to form a suspension of the nanoparticles, each nanoparticle having one or more cores and a shell encapsulating the one or more cores, layering the suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container, and centrifugating the layered suspension of the nanoparticles on the top of the high-viscosity density gradient medium in the container at a predetermined speed for a predetermined period of time to form a gradient of fractions of the nanoparticles along the container, where each fraction comprises nanoparticles in a respective one of aggregation states of the nanoparticles.
FILED	Tuesday, May 01, 2012
APPL NO	13/461521
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101)
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09802834 — Production of nanocrystalline metal powders via combustion reaction synthesis

US 09802834	Frye et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	John G. Frye (Richland, Washington); Kenneth Scott Weil (Richland, Washington); Curt A. Lavender (Richland, Washington); Jin Yong Kim (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	John G. Frye (Richland, Washington); Kenneth Scott Weil (Richland, Washington); Curt A. Lavender (Richland, Washington); Jin Yong Kim (Richland, Washington)
ABSTRACT	Nanocrystalline metal powders comprising tungsten, molybdenum, rhenium and/or niobium can be synthesized using a combustion reaction. Methods for synthesizing the nanocrystalline metal powders are characterized by forming a combustion synthesis solution by dissolving in water an oxidizer, a fuel, and a base-soluble, ammonium precursor of tungsten, molybdenum, rhenium, or niobium in amounts that yield a stoichiometric burn when combusted. The combustion synthesis solution is then heated to a temperature sufficient to substantially remove water and to initiate a self-sustaining combustion reaction. The resulting powder can be subsequently reduced to metal form by heating in a reducing gas environment.
FILED	Friday, February 05, 2010
APPL NO	12/700923
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0044 (20130101) B22F 9/24 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 33/00 (20130101) C01G 39/02 (20130101) Original (OR) Class C01G 41/02 (20130101) C01G 47/00 (20130101) Alloys C22C 1/045 (20130101) C22C 1/058 (20130101) C22C 27/04 (20130101)
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09803136 — Liquid electrolyte-free, solid-state solar cells with inorganic hole transport materials

US 09803136	Kanatzidis et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Mercouri G. Kanatzidis (Wilmette, Illinois); In Chung (Evanston, Illinois); Byunghong Lee (Evanston, Illinois); Robert P. H. Chang (Glenview, Illinois)
ABSTRACT	Photovoltaic cells incorporating the compounds A/M/X compounds as hole transport materials are provide. The A/M/X compounds comprise one or more A moieties, one or more M atoms and one or more X atoms. The A moieties are selected from organic cations and elements from Group 1 of the periodic table, the M atoms are selected from elements from at least one of Groups 3, 4, 5, 13, 14 or 15 of the periodic table, and the X atoms are selected from elements from Group 17 of the periodic table.
FILED	Thursday, February 21, 2013
APPL NO	13/772794
ART UNIT	1756 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/665 (20130101) Original (OR) Class C09K 2211/10 (20130101) Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 2/00 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 9/04 (20130101) F21V 9/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/20 (20130101) H01G 9/2059 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/032 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/542 (20130101)
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09803142 — Catalysts and methods for converting carbonaceous materials to fuels

US 09803142	Hensley et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Jesse Hensley (Arvada, Colorado); Daniel A. Ruddy (Lafayette, Colorado); Joshua A. Schaidle (Arvada, Colorado); Mayank Behl (Lakewood, Colorado)
ABSTRACT	Catalysts and processes designed to convert DME and/or methanol and hydrogen (H₂) to desirable liquid fuels are described. These catalysts produce the fuels efficiently and with a high selectivity and yield, and reduce the formation of aromatic hydrocarbons by incorporating H₂into the products. Also described are process methods to further upgrade these fuels to higher molecular weight liquid fuel mixtures, which have physical properties comparable with current commercially used liquid fuels.
FILED	Thursday, June 08, 2017
APPL NO	15/617026
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/7057 (20130101) B01J 29/7615 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/02 (20130101) C01B 3/22 (20130101) C01B 3/34 (20130101) C01B 2203/02 (20130101) C01B 2203/06 (20130101) C01B 2203/025 (20130101) C01B 2203/061 (20130101) C01B 2203/0216 (20130101) C01B 2203/0222 (20130101) C01B 2203/0266 (20130101) C01B 2203/0283 (20130101) C01B 2203/1241 (20130101) Acyclic or Carbocyclic Compounds C07C 29/1518 (20130101) C07C 41/01 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/49 (20130101) Original (OR) Class C10G 3/50 (20130101) C10G 50/00 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 2300/1665 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 2200/0492 (20130101) C10L 2290/02 (20130101) C10L 2290/04 (20130101) C10L 2290/42 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) Y02P 30/20 (20151101)
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09803153 — Radiant non-catalytic recuperative reformer

US 09803153	Khinkis et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Mark J. Khinkis (Morton Grove, Illinois); Aleksandr P. Kozlov (Buffalo Grove, Illinois)
ASSIGNEE(S)	Gas Technology Institute (Des Plaines, Illinois)
INVENTOR(S)	Mark J. Khinkis (Morton Grove, Illinois); Aleksandr P. Kozlov (Buffalo Grove, Illinois)
ABSTRACT	A radiant, non-catalytic recuperative reformer has a flue gas flow path for conducting hot exhaust gas from a thermal process and a reforming mixture flow path for conducting a reforming mixture. At least a portion of the reforming mixture flow path is positioned adjacent to the flue gas flow path to permit heat transfer from the hot exhaust gas to the reforming mixture. The reforming mixture flow path contains substantially no material commonly used as a catalyst for reforming hydrocarbon fuel (e.g., nickel oxide, platinum group elements or rhenium), but instead the reforming mixture is reformed into a higher calorific fuel via reactions due to the heat transfer and residence time. In a preferred embodiment, a portion of the reforming mixture flow path is positioned outside of flue gas flow path for a relatively large residence time.
FILED	Monday, December 21, 2015
APPL NO	14/976307
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 12/007 (20130101) B01J 19/248 (20130101) B01J 19/249 (20130101) B01J 19/2425 (20130101) B01J 2219/00081 (20130101) B01J 2219/00085 (20130101) B01J 2219/00087 (20130101) B01J 2219/00099 (20130101) B01J 2219/00157 (20130101) B01J 2219/00159 (20130101) B01J 2219/2453 (20130101) B01J 2219/2458 (20130101) B01J 2219/2462 (20130101) B01J 2219/2479 (20130101) B01J 2219/2482 (20130101) B01J 2219/2486 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/34 (20130101) C01B 2203/148 (20130101) C01B 2203/0216 (20130101) C01B 2203/0222 (20130101) C01B 2203/0811 (20130101) C01B 2203/1235 (20130101) C01B 2203/1241 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/00 (20130101) Original (OR) Class
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09803182 — Ionic liquid-tolerant cellulase enzymes

US 09803182	Gladden et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	The Regents of the University of California (Oakland, California); Sandia Corporation (Livermore, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); Sandia Corporation (Livermore, California)
INVENTOR(S)	John Gladden (Alameda, California); Joshua Park (San Diego, California); Steven Singer (Berkeley, California); Blake Simmons (San Francisco, California); Ken Sale (Livermore, California)
ABSTRACT	The present invention provides ionic liquid-tolerant cellulases and method of producing and using such cellulases. The cellulases of the invention are useful in saccharification reactions using ionic liquid treated biomass.
FILED	Monday, February 02, 2015
APPL NO	14/612201
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) C12N 9/2445 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 302/01021 (20130101)
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09803221 — Engineering microorganisms to increase ethanol production by metabolic redirection

US 09803221	Deng et al.
FUNDED BY	Department of Energy (DOE) BioEnergy Science Center (BESC) Office of Science (DOE-SC)
APPLICANT(S)	Enchi Corporation (Wellesley Hills, Massachusetts); Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S)	Enchi Corporation (Wellesley Hills, Massachusetts); Dartmouth College (Hanover, New Hampshire)
INVENTOR(S)	Yu Deng (West Lebanon, New Hampshire); Daniel G. Olson (Norwich, Vermont); Johannes Pieter van Dijken (Schiedam, Netherlands); Arthur J. Shaw, IV (Grantham, New Hampshire); Aaron Argyros (White River Junction, Vermont); Trisha Barrett (Bradford, Vermont); Nicky Caiazza (Rancho Santa Fe, California); Christopher D. Herring (Lebanon, New Hampshire); Stephen R. Rogers (Hanover, New Hampshire); Frank Agbogbo (Lebanon, New Hampshire)
ABSTRACT	The present invention provides for the manipulation of carbon flux in a recombinant host cell to increase the formation of desirable products. The invention relates to cellulose-digesting organisms that have been genetically modified to allow the production of ethanol at a high yield by redirecting carbon flux at key steps of central metabolism.
FILED	Friday, September 28, 2012
APPL NO	14/348231
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/88 (20130101) C12N 9/1029 (20130101) C12N 9/1205 (20130101) C12N 9/1217 (20130101) C12N 9/1294 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 7/065 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101)
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09803238 — Method and apparatus for purifying nucleic acids and performing polymerase chain reaction assays using an immiscible fluid

US 09803238	Koh et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Chung-Yan Koh (Dublin, California); Yooli Kim Light (Pleasanton, California); Matthew Ernest Piccini (Belmont, California); Anup K. Singh (Danville, California)
ABSTRACT	Embodiments of the present invention are directed toward devices, systems, and methods for purifying nucleic acids to conduct polymerase chain reaction (PCR) assays. In one example, a method includes generating complexes of silica beads and nucleic acids in a lysis buffer, transporting the complexes through an immiscible fluid to remove interfering compounds from the complexes, further transporting the complexes into a density medium containing components required for PCR where the nucleic acids disassociate from the silica beads, and thermocycling the contents of the density medium to achieve PCR. Signal may be detected from labeling agents in the components required for PCR.
FILED	Tuesday, November 26, 2013
APPL NO	14/090040
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class
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09803285 — Electroless atomic layer deposition

US 09803285	Robinson et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	David Bruce Robinson (Hayward, California); Patrick J. Cappillino (Fremont, California); Leah B. Sheridan (Knoxville, Tennessee); John L. Stickney (Athens, Georgia); David M. Benson (Athens, Georgia)
ABSTRACT	A method of electroless atomic layer deposition is described. The method electrolessly generates a layer of sacrificial material on a surface of a first material. The method adds doses of a solution of a second material to the substrate. The method performs a galvanic exchange reaction to oxidize away the layer of the sacrificial material and deposit a layer of the second material on the surface of the first material. The method can be repeated for a plurality of iterations in order to deposit a desired thickness of the second material on the surface of the first material.
FILED	Tuesday, February 25, 2014
APPL NO	14/189866
ART UNIT	1754 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/02 (20130101) C23C 8/06 (20130101) C23C 16/02 (20130101) C23C 18/44 (20130101) C23C 18/1834 (20130101) C23C 28/00 (20130101) Original (OR) Class
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09803487 — Converging flow joint insert system at an intersection between adjacent transitions extending between a combustor and a turbine assembly in a gas turbine engine

US 09803487	Wiebe et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Siemens Energy, Inc. (Orlando, Florida)
ASSIGNEE(S)	SIEMENS ENERGY, INC. (Orlando, Florida)
INVENTOR(S)	David J. Wiebe (Orlando, Florida); Andrew Carlson (Jupiter, Florida); Kyle C. Stoker (North Palm Beach, Florida)
ABSTRACT	A transition duct system for routing a gas flow in a combustion turbine engine is provided. The transition duct system includes one or more converging flow joint inserts forming a trailing edge at an intersection between adjacent transition ducts. The converging flow joint insert may be contained within a converging flow joint insert receiver and may be disconnected from the transition duct bodies by which the converging flow joint insert is positioned. Being disconnected eliminates stress formation within the converging flow joint insert, thereby enhancing the life of the insert. The converging flow joint insert may be removable such that the insert can be replaced once worn beyond design limits.
FILED	Thursday, June 26, 2014
APPL NO	15/318078
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 9/00 (20130101) F01D 9/02 (20130101) F01D 9/023 (20130101) Original (OR) Class F01D 9/047 (20130101) F01D 9/065 (20130101) F01D 25/28 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/14 (20130101) F02C 7/20 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/10 (20130101) F05D 2260/20 (20130101) F05D 2260/94 (20130101) F05D 2260/941 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/46 (20130101) F23R 3/60 (20130101) F23R 3/425 (20130101) F23R 2900/00005 (20130101)
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09804161 — Detector and related, devices, methods and systems

US 09804161	Bearinger
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Jane P. Bearinger (Berwyn, Pennsylvania)
ABSTRACT	Detectors and related methods and systems are described, based on a primary binding compound and a secondary binding compound used in combination with a support to detect a target in a sample.
FILED	Monday, May 13, 2013
APPL NO	13/893315
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/558 (20130101) G01N 33/571 (20130101) Original (OR) Class G01N 33/54366 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 435/97 (20130101) Y10S 435/973 (20130101)
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09805172 — System and methods of resource usage using an interoperable management framework

US 09805172	Heileman et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Gregory L. Heileman (Albuquerque, New Mexico); Pramod A. Jamkhedkar (Albuquerque, New Mexico); Christopher C. Lamb (Albuquerque, New Mexico)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Gregory L. Heileman (Albuquerque, New Mexico); Pramod A. Jamkhedkar (Albuquerque, New Mexico); Christopher C. Lamb (Albuquerque, New Mexico)
ABSTRACT	Generic rights expression language allowing interoperability across different computing environments including resource usage of different applications. A formal framework for usage management provides scaffolding upon which interoperable usage management systems can be built. Certain features of the framework are standardized, such as the operational semantics, including areas free of standards that necessitate choice and innovation to achieve a balance of flexibility and usability for interoperability in usage management systems.
FILED	Wednesday, November 17, 2010
APPL NO	13/510088
ART UNIT	2437 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/10 (20130101) Original (OR) Class G06F 2221/0759 (20130101)
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09805921 — Ambient infrared laser ablation mass spectrometry (AIRLAB-MS) with plume capture by continuous flow solvent probe

US 09805921	O'Brien et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Jeremy T. O'Brien (Cambridge, Massachusetts); Evan R. Williams (Oakland, California); Hoi-Ying N. Holman (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Jeremy T. O'Brien (Cambridge, Massachusetts); Evan R. Williams (Oakland, California); Hoi-Ying N. Holman (Oakland, California)
ABSTRACT	A new experimental setup for spatially resolved ambient infrared laser ablation mass spectrometry (AIRLAB-MS) that uses an infrared microscope with an infinity-corrected reflective objective and a continuous flow solvent probe coupled to a Fourier transform ion cyclotron resonance mass spectrometer is described. The efficiency of material transfer from the sample to the electrospray ionization emitter was determined using glycerol/methanol droplets containing 1 mM nicotine and is ˜50%. This transfer efficiency is significantly higher than values reported for similar techniques.
FILED	Monday, June 15, 2015
APPL NO	14/740176
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/167 (20130101) H01J 49/0463 (20130101) Original (OR) Class
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09806259 — Patterning devices using fluorinated compounds

US 09806259	Katz et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Howard E. Katz (Owings Mills, Maryland); Bal Mukund Dhar (Baltimore, Maryland)
ABSTRACT	A method for producing a spatially patterned structure includes forming a layer of a material on at least a portion of a substructure of the spatially patterned structure, forming a barrier layer of a fluorinated material on the layer of material to provide an intermediate structure, and exposing the intermediate structure to at least one of a second material or radiation to cause at least one of a chemical change or a structural change to at least a portion of the intermediate structure. The barrier layer substantially protects the layer of the material from chemical and structural changes during the exposing. Substructures are produced according to this method.
FILED	Tuesday, August 02, 2016
APPL NO	15/226411
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0035 (20130101) G03F 7/70058 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0014 (20130101) H01L 51/0018 (20130101) Original (OR) Class H01L 51/0023 (20130101) H01L 51/52 (20130101) H01L 51/0097 (20130101) H01L 51/102 (20130101) H01L 51/0541 (20130101) H01L 51/0545 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24479 (20150115)
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09806306 — Impact resistant battery enclosure systems

US 09806306	Tsutsui et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S)	Waterloo Tsutsui (West Lafayette, Indiana); Yuezhong Feng (Henan, China PRC); Weinong Wayne Chen (West Lafayette, Indiana); Thomas Heinrich Siegmund (West Lafayette, Indiana)
ABSTRACT	Battery enclosure arrangements for a vehicular battery system. The arrangements, capable of impact resistance include plurality of battery cells and a plurality of kinetic energy absorbing elements. The arrangements further include a frame configured to encase the plurality of the kinetic energy absorbing elements and the battery cells. In some arrangements the frame and/or the kinetic energy absorbing elements can be made of topologically interlocked materials.
FILED	Monday, November 24, 2014
APPL NO	14/551670
ART UNIT	1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Fire-fighting A62C 3/07 (20130101) A62C 3/16 (20130101) A62C 99/0045 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1077 (20130101) H01M 2/1094 (20130101) Original (OR) Class H01M 2220/20 (20130101)
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09806338 — Nanoporous titanium niobium oxide and titanium tantalum oxide compositions and their use in anodes of lithium ion batteries

US 09806338	Dai et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-BATTELE, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Sheng Dai (Knoxville, Tennessee); Bingkun Guo (Knoxville, Tennessee); Xiao-Guang Sun (Knoxville, Tennessee); Zhenan Qiao (Oak Ridge, Tennessee)
ABSTRACT	Nanoporous metal oxide framework compositions useful as anodic materials in a lithium ion battery, the composition comprising metal oxide nanocrystals interconnected in a nanoporous framework and having interconnected channels, wherein the metal in said metal oxide comprises titanium and at least one metal selected from niobium and tantalum, e.g., TiNb_2-xTa_xO_y(wherein x is a value from 0 to 2, and y is a value from 7 to 10) and Ti₂Nb_10-vTa_vO_w(wherein v is a value from 0 to 2, and w is a value from 27 to 29). A novel sol gel method is also described in which sol gel reactive precursors are combined with a templating agent under sol gel reaction conditions to produce a hybrid precursor, and the precursor calcined to form the anodic composition. The invention is also directed to lithium ion batteries in which the nanoporous framework material is incorporated in an anode of the battery.
FILED	Friday, August 23, 2013
APPL NO	13/974544
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 33/00 (20130101) C01G 35/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2006/12 (20130101) C01P 2006/16 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/485 (20130101) Original (OR) Class H01M 10/0525 (20130101)
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09806366 — Method and system for rebalancing electrolytes in a redox flow battery system

US 09806366	Song et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	ESS TECH, INC. (Portland, Oregon)
ASSIGNEE(S)	ESS Tech, Inc. (Portland, Oregon)
INVENTOR(S)	Yang Song (West Linn, Oregon); Craig E. Evans (West Linn, Oregon)
ABSTRACT	A redox flow battery system is provided. The system includes a positive electrode in fluid communication with a positive electrolyte comprising a first metal ion and a negative electrode in fluid communication with a negative electrolyte comprising a second metal ion. An electrically insulating ion conducting surface is provided separating the positive electrode from the negative electrode. Further, the system includes a catalyst surface in fluid communication with the first metal ion, the second metal ion, or a combination thereof, and hydrogen gas, wherein the hydrogen gas and the first metal ion, the second metal ion, or a combination thereof are fluidly contacted at the catalyst surface.
FILED	Tuesday, October 18, 2016
APPL NO	15/297011
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/20 (20130101) H01M 8/188 (20130101) H01M 8/0693 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101)
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RE046594 — Electrochemical detection of single molecules using abiotic nanopores having electrically tunable dimensions

US RE46594	Sansinena et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS)
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Jose-Maria Sansinena (Los Alamos, New Mexico); Antonio Redondo (Los Alamos, New Mexico); Virginia Olazabal (Los Alamos, New Mexico); Mark A. Hoffbauer (Los Alamos, New Mexico); Elshan A. Akhadov (Los Alamos, New Mexico)
ABSTRACT	A barrier structure for use in an electrochemical stochastic membrane sensor for single molecule detection. The sensor is based upon inorganic nanopores having electrically tunable dimensions. The inorganic nanopores are formed from inorganic materials and an electrically conductive polymer. Methods of making the barrier structure and sensing single molecules using the barrier structure are also described.
FILED	Wednesday, May 28, 2014
APPL NO	14/289445
ART UNIT	3991 — Central Reexamination Unit (Chemical)
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101)
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Department of Commerce (DOC)

09801772 — Human machine interfaces for lower extremity orthotics

US 09801772	Kazerooni et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Katherine Strausser (Berkeley, California); Adam Zoss (Berkeley, California); Tim Swift (Albany, California)
ASSIGNEE(S)	Ekso Bionics, Inc. (Richmond, California); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Homayoon Kazerooni (Oakland, California); Katherine Strausser (Berkeley, California); Adam Zoss (Berkeley, California); Tim Swift (Albany, California)
ABSTRACT	A system and method by which movements desired by a user of a lower extremity orthotic is determined and a control system automatically regulates the sequential operation of powered lower extremity orthotic components to enable the user, having mobility disorders, to walk, as well as perform other common mobility tasks which involve leg movements, perhaps with the use of a gait aid.
FILED	Thursday, October 06, 2011
APPL NO	13/877805
ART UNIT	3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/00 (20130101) Original (OR) Class A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 3/00 (20130101) A61H 3/02 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/1616 (20130101) A61H 2201/1642 (20130101) A61H 2201/5007 (20130101) A61H 2201/5028 (20130101) A61H 2201/5069 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2201/5092 (20130101)
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09804138 — Measurement of total reactive nitrogen, NO_y, together with NO₂, NO, and O₃via cavity ring-down spectroscopy

US 09804138	Brown et al.
FUNDED BY	Department of Commerce (DOC) National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America (Washington, District of Columbia)
INVENTOR(S)	Steven S. Brown (Boulder, Colorado); William P. Dubé (Wheat Ridge, Colorado); Robert J. Wild (Boulder, Colorado)
ABSTRACT	A sensitive, compact detector measures total reactive nitrogen (NO_y), as well as NO₂, NO, and O₃. In all channels, NO₂is directly detected by laser diode based cavity ring-down spectroscopy (CRDS) at 405 nm. Ambient O₃is converted to NO₂in excess NO for the O₃measurement channel. Likewise, ambient NO is converted to NO₂in excess O₃. Ambient NO_yis thermally dissociated at 700 C to form NO₂or NO in a heated quartz inlet. Any NO present in ambient air or formed from thermal dissociation of other reactive nitrogen compounds is converted to NO₂in excess O₃after the thermal converter. The precision and accuracy of this instrument make it a versatile alternative to standard chemiluminescence-based NO_yinstruments.
FILED	Wednesday, May 27, 2015
APPL NO	14/722214
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0016 (20130101) G01N 33/0037 (20130101) Original (OR) Class
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09804891 — Parallelizing multiple signing and verifying operations within a secure routing context

US 09804891	Adalier
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Antara Teknik LLC (Granite Bay, California)
ASSIGNEE(S)	Antara Teknik LLC (Granite Bay, California)
INVENTOR(S)	Mehmet Yavuz Adalier (Granite Bay, California)
ABSTRACT	A networking device continuously and simultaneously receives multiple sign and verify requests, without a priori knowledge of their quantity, type, sequence, length, input data or frequency. The networking device performs the corresponding signature operations and verification operations according to a rule based configuration. Each received sign and verify request is broken into multiple tasks, which are placed into a task pool with priorities, and disassociated from their originating requests and from other tasks. Multiple execution agents (each one a separate general purpose compute unit with its own memory space) repeatedly and simultaneously processes next available tasks from the pool based on priority. Asynchronous worker routines in the agents can pre-calculate certain values for higher level task processing. The output from completed tasks is placed into a repository, and the results in the repository are processed to fulfill the multiple received requests at network line speed.
FILED	Monday, March 21, 2016
APPL NO	15/076540
ART UNIT	2196 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/5038 (20130101) Original (OR) Class G06F 9/5083 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 45/70 (20130101) H04L 63/20 (20130101) H04L 63/123 (20130101) H04L 63/1416 (20130101)
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Department of Homeland Security (DHS)

09804028 — External cavity laser source

US 09804028	Vukovic-Cvijin
FUNDED BY	Department of Homeland Security (DHS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Spectral Sciences, Inc. (Burlington, Massachusetts)
ASSIGNEE(S)	Spectral Sciences, Inc. (Burlington, Massachusetts)
INVENTOR(S)	Pajo Vukovic-Cvijin (Salem, Massachusetts)
ABSTRACT	A tunable laser source that includes multiple gain elements and uses a spatial light modulator in an external cavity to produce spectrally tunable output is claimed. Several designs of the external cavity are described, targeting different performance characteristics and different manufacturing costs for the device. Compared to existing devices, the tunable laser source produces high output power, wide tuning range, fast tuning rate, and high spectral resolution.
FILED	Saturday, February 07, 2015
APPL NO	14/616673
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/18 (20130101) G01J 3/0229 (20130101) G01J 3/433 (20130101) Original (OR) Class G01J 2003/423 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0816 (20130101) H01S 3/08009 (20130101) H01S 5/141 (20130101) H01S 5/1092 (20130101) H01S 5/02248 (20130101) H01S 5/3402 (20130101) H01S 5/4062 (20130101) H01S 5/4087 (20130101)
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09805923 — Mass separators, mass selective detectors, and methods for optimizing mass separation within mass selective detectors

US 09805923	Goodwin et al.
FUNDED BY	Department of Homeland Security (DHS) Science and Technology Directorate (DHS-ST)
APPLICANT(S)	FLIR Detection, Inc. (Stillwater, Oklahoma)
ASSIGNEE(S)	FLIR Detection, Inc. (Stillwater, Oklahoma)
INVENTOR(S)	Michael Goodwin (Brookline, Massachusetts); James Mitchell Wells (Lafayette, Indiana)
ABSTRACT	Mass separators are provided that can include at least one electrode component having a surface, in one cross section, defining at least two runs associated via at least one rise, the rise being orthogonally related to the runs. Mass selective detectors are provided that can include at least a first pair of opposing electrodes with each of the opposing electrodes having a complimentary surface, in one cross section, defining at least two runs associated via a rise. Methods for optimizing mass separation within a mass selective detector are also provided, including providing mass separation parameters; providing one set electrodes within the separator having a surface operatively aligned within the separator, the surface, in one cross section, defining at least two runs associated via a rise, the rise being orthogonally related to the runs; and modifying one or both of the rise and/or runs to achieve the mass separation parameters.
FILED	Wednesday, May 13, 2015
APPL NO	14/711677
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/06 (20130101) H01J 49/26 (20130101) H01J 49/0031 (20130101) H01J 49/423 (20130101) H01J 49/4215 (20130101) H01J 49/4255 (20130101) Original (OR) Class
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09807105 — Adaptive behavior profiling and anomaly scoring through continuous learning

US 09807105	Cheng et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Pau-Chen Cheng (Yorktown Heights, New York); Lawrence Koved (Pleasantville, New York); Kapil K. Singh (Cary, North Carolina)
ABSTRACT	Generating a behavior profile is provided. A newness score is calculated for a data point corresponding to a context of an access request to a resource made by a user of a client device. Newness scores for a plurality of data points corresponding to contexts of a plurality of access requests are aggregated to form an aggregated newness score. In response to determining that the aggregated newness score is greater than or equal to a pre-defined newness score threshold, data points stored in a data point cache and a long-term storage are used to generate a new behavior profile for the user or update an existing behavior profile for the user.
FILED	Wednesday, November 11, 2015
APPL NO	14/938415
ART UNIT	2436 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) Original (OR) Class H04L 67/306 (20130101) H04L 67/2842 (20130101)
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National Aeronautics and Space Administration (NASA)

09802149 — Sorbent-based atmosphere revitalization system

US 09802149	Knox et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S)	James C Knox (Union Grove, Alabama); Lee A. Miller (Huntsville, Alabama)
ABSTRACT	The present invention is a sorbent-based atmosphere revitalization (SBAR) system using treatment beds each having a bed housing, primary and secondary moisture adsorbent layers, and a primary carbon dioxide adsorbent layer. Each bed includes a redirecting plenum between moisture adsorbent layers, inlet and outlet ports connected to inlet and outlet valves, respectively, and bypass ports connected to the redirecting plenums. The SBAR system also includes at least one bypass valve connected to the bypass ports. An inlet channel connects inlet valves to an atmosphere source. An outlet channel connects the bypass valve and outlet valves to the atmosphere source. A vacuum channel connects inlet valves, the bypass valve and outlet valves to a vacuum source. In use, one bed treats air from the atmosphere source while another bed undergoes regeneration. During regeneration, the inlet, bypass, and outlet valves sequentially open to the vacuum source, removing accumulated moisture and carbon dioxide.
FILED	Wednesday, December 16, 2015
APPL NO	14/971256
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/0415 (20130101) B01D 53/0446 (20130101) Original (OR) Class B01D 53/0454 (20130101) B01D 2253/108 (20130101) B01D 2253/116 (20130101) B01D 2257/80 (20130101) B01D 2257/504 (20130101) B01D 2259/4145 (20130101) B01D 2259/4148 (20130101) B01D 2259/4575 (20130101)
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09802209 — Fluidic oscillator having decoupled frequency and amplitude control

US 09802209	Koklu
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY NASA (Washington, District of Columbia)
INVENTOR(S)	Mehti Koklu (Hampton, Virginia)
ABSTRACT	A fluidic oscillator having independent frequency and amplitude control includes a fluidic-oscillator main flow channel having a main flow inlet, a main flow outlet, and first and second control ports disposed at opposing sides thereof. A fluidic-oscillator controller has an inlet and outlet. A volume defined by the main flow channel is greater than the volume defined by the controller. A flow diverter coupled to the outlet of the controller defines a first fluid flow path from the controller's outlet to the first control port and defines a second fluid flow path from the controller's outlet to the second control port.
FILED	Wednesday, May 04, 2016
APPL NO	15/146484
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/08 (20130101) Original (OR) Class Fluid-circuit Elements Predominantly Used for Computing or Control Purposes F15C 1/22 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/003 (20130101) F15D 1/009 (20130101)
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09804199 — Ephemeral electric potential and electric field sensor

US 09804199	Generazio
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY NASA (Washington, District of Columbia)
INVENTOR(S)	Edward R. Generazio (Yorktown, Virginia)
ABSTRACT	Systems, methods, and devices of the various embodiments provide for the minimization of the effects of intrinsic and extrinsic leakage electrical currents enabling true measurements of electric potentials and electric fields. In an embodiment, an ephemeral electric potential and electric field sensor system may have at least one electric field sensor and a rotator coupled to the electric field sensor and be configured to rotate the electric field sensor at a quasi-static frequency. In an embodiment, ephemeral electric potential and electric field measurements may be taken by rotating at least one electric field sensor at a quasi-static frequency, receiving electrical potential measurements from the electric field sensor when the electric field sensor is rotating at the quasi-static frequency, and generating and outputting images based at least in part on the received electrical potential measurements.
FILED	Wednesday, November 19, 2014
APPL NO	14/547390
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 13/0218 (20130101) Original (OR) Class G01R 29/12 (20130101)
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Department of Agriculture (USDA)

09804097 — Crop stand analyzer using reflective laser proximity sensors

US 09804097	Tang et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	Lie Tang (Ames, Iowa); Ji Li (Ames, Iowa); Yin Bao (Ames, Iowa); Jian Jin (Johnston, Iowa); Akash Dev Nakarmi (Ames, Iowa)
ABSTRACT	A crop stand analyzer includes a first plurality of reflective laser proximity sensors, the reflective laser proximity sensors arranged in a vertical row and perpendicularly to a ground surface to detect plant objects, a distance sensor, and a processor operatively connected to the first plurality of reflective laser proximity sensors and the distance sensor. The crop stand analyzer is configured to generate side-view profiles for the plant objects and then extract plant stand information via these profiles.
FILED	Wednesday, May 20, 2015
APPL NO	14/717613
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/84 (20130101) Original (OR) Class G01N 2021/8466 (20130101) G01N 2201/021 (20130101) G01N 2201/06113 (20130101)
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PP028581 — Apple tree rootstock named ‘G.213’

US PP28581	Fazio et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Cornell University (Ithaca, New York); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	Cornell University (Ithaca, New York); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Gennaro Fazio (Geneva, New York); Herb Aldwinckle (Geneva, New York); James Cummins (Alcoa, Tennessee); Terence Robinson (Geneva, New York)
ABSTRACT	The present invention relates to a new and distinct variety of apple tree Malus domestica×Malus robusta hybrid named ‘G.213’. ‘G.213’ is useful in that it can be propagated clonally and used as a rootstock or root system for apple trees as well as for interstems of apple trees. The new variety is a dwarfing rootstock that is resistant to fire blight (Erwinia amylovora) and crown rot (Phytophthora cactorum).
FILED	Wednesday, September 30, 2015
APPL NO	14/756708
ART UNIT	1661 — Plants
CURRENT CPC	Plants PLT/161
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Small Business Administration (SBA)

09804028 — External cavity laser source

US 09804028	Vukovic-Cvijin
FUNDED BY	Department of Homeland Security (DHS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Spectral Sciences, Inc. (Burlington, Massachusetts)
ASSIGNEE(S)	Spectral Sciences, Inc. (Burlington, Massachusetts)
INVENTOR(S)	Pajo Vukovic-Cvijin (Salem, Massachusetts)
ABSTRACT	A tunable laser source that includes multiple gain elements and uses a spatial light modulator in an external cavity to produce spectrally tunable output is claimed. Several designs of the external cavity are described, targeting different performance characteristics and different manufacturing costs for the device. Compared to existing devices, the tunable laser source produces high output power, wide tuning range, fast tuning rate, and high spectral resolution.
FILED	Saturday, February 07, 2015
APPL NO	14/616673
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/18 (20130101) G01J 3/0229 (20130101) G01J 3/433 (20130101) Original (OR) Class G01J 2003/423 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0816 (20130101) H01S 3/08009 (20130101) H01S 5/141 (20130101) H01S 5/1092 (20130101) H01S 5/02248 (20130101) H01S 5/3402 (20130101) H01S 5/4062 (20130101) H01S 5/4087 (20130101)
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09806226 — Deep ultraviolet light emitting diode

US 09806226	Gaska et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
ASSIGNEE(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
INVENTOR(S)	Remigijus Gaska (Columbia, South Carolina); Maxim S. Shatalov (Columbia, South Carolina); Michael Shur (Latham, New York); Alexander Dobrinsky (Loudonville, New York)
ABSTRACT	A method of fabricating a light emitting diode, which includes an n-type contact layer and a light generating structure adjacent to the n-type contact layer, is provided. The light generating structure includes a set of quantum wells. The contact layer and light generating structure can be configured so that a difference between an energy of the n-type contact layer and an electron ground state energy of a quantum well is greater than an energy of a polar optical phonon in a material of the light generating structure. Additionally, the light generating structure can be configured so that its width is comparable to a mean free path for emission of a polar optical phonon by an electron injected into the light generating structure.
FILED	Tuesday, September 06, 2016
APPL NO	15/257316
ART UNIT	2822 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/04 (20130101) H01L 33/06 (20130101) Original (OR) Class H01L 33/10 (20130101) H01L 33/22 (20130101) H01L 33/0025 (20130101) H01L 33/32 (20130101) H01L 33/38 (20130101) H01L 33/46 (20130101) H01L 33/0075 (20130101) H01L 33/145 (20130101) H01L 33/385 (20130101) H01L 33/405 (20130101) H01L 2933/0058 (20130101)
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Department of Justice (DOJ)

09804178 — Materials and methods for rapid and specific detection of cocaine

US 09804178	Roncancio et al.
FUNDED BY	Department of Justice (DOJ) Office of Justice Programs (OJP) National Institute of Justice (NIJ)
APPLICANT(S)	Daniel Roncancio (Miami, Florida); Haixiang Yu (Miami, Florida); Xiaowen Xu (Miami, Florida); Yi Xiao (Miami, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S)	Daniel Roncancio (Miami, Florida); Haixiang Yu (Miami, Florida); Xiaowen Xu (Miami, Florida); Yi Xiao (Miami, Florida)
ABSTRACT	The invention pertains to a rapid and specific aptamer-based method for one-step cocaine detection with minimal reagent requirements based on an aptamer sensor that reports the presence of cocaine via the displacement and unquenching of a bound fluorophore molecule. In certain embodiments, the invention provides novel aptamers, which have reduced background fluorescence, bind a fluorophore molecule tightly, and show an increased signal gain in the presence of cocaine.
FILED	Monday, November 02, 2015
APPL NO	14/930242
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2320/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/946 (20130101) Original (OR) Class
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Department of Transportation (USDOT)

09802631 — Route examining system

US 09802631	Matthews et al.
FUNDED BY	Department of Transportation (USDOT) Federal Railroad Administration (FRA)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Niskayuna, New York)
INVENTOR(S)	Brett Alexander Matthews (Niskayuna, New York); Gregory Boverman (Niskayuna, New York); Yuri Alexeyevich Plotnikov (Niskayuna, New York); Frederick Wilson Wheeler (Niskayuna, New York); Majid Nayeri (Niskayuna, New York); Jeffrey Michael Fries (Grain Valley, Missouri)
ABSTRACT	Systems for examining a route inject one or more electrical examination signals into a conductive route from onboard a vehicle system traveling along the route, detect one or more electrical characteristics of the route based on the one or more electrical examination signals, and detect a break in conductivity of the route responsive to the one or more electrical characteristics decreasing by more than a designated drop threshold for a time period within a designated drop time period. Feature vectors may be determined for the electrical characteristics and compared to one or more patterns in order to distinguish between breaks in the conductivity of the route and other causes for changes in the electrical characteristics.
FILED	Thursday, February 18, 2016
APPL NO	15/047083
ART UNIT	3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 3/10 (20130101) B61L 23/044 (20130101) Original (OR) Class
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Department of Veterans Affairs (DVA)

09801865 — Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with abeta peptide aggregation

US 09801865	Moran
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Valentina Echeverria Moran (Largo, Florida)
ASSIGNEE(S)	The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia); University of South Florida (Tampa, Florida)
INVENTOR(S)	Valentina Echeverria Moran (Largo, Florida)
ABSTRACT	The subject invention concerns materials and methods for treating and/or preventing diseases associated with accumulation of Aβ peptide in neural tissue. The subject invention also concerns materials and methods for treating and/or preventing stress disorders, such as post-traumatic stress disorder (PTSD). In one embodiment, a method of the invention comprises administering a therapeutically effective amount of cotinine, or a pharmaceutically acceptable salt thereof, to a person or animal in need of treatment. The methods of the invention can be used to prevent and/or treat Alzheimer's disease and Parkinson's disease. The subject invention also concerns compositions that comprise cotinine, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or adjuvant. The subject invention concerns materials and methods for detecting and diagnosing conditions associated with accumulation of Aβ peptide in neural tissue, such as Alzheimer's disease and Parkinson's disease, using the chemical cotinine.
FILED	Thursday, September 24, 2009
APPL NO	12/586681
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/4439 (20130101) Original (OR) Class A61K 51/0455 (20130101) Heterocyclic Compounds C07D 401/04 (20130101)
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Department of the Interior (DOI)

09803978 — Laser rod surface elevation table device and method

US 09803978	Vervaeke et al.
FUNDED BY	Department of the Interior (DOI)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of the Interior (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S)	William C. Vervaeke (Duson, Louisiana); Christopher J. Wells (Saline, Louisiana); Ryan M. Twilley (Lafayette, Louisiana); David P. Turnipseed (Breaux Bridge, Louisiana)
ABSTRACT	A laser rod surface elevation table (L-RSET) includes a sensor arm coupled to a stepper motor and a screw frame. A screw interconnects the motor and frame, while a screw carriage interconnects the screw and a sensor carriage. A laser sensor is mounted to the sensor carriage. A controller includes at least one processor operatively coupled to the sensor and motor. The processor processes measurement values in a data structure and performs functions to actuate the motor and sensor. The data structure represents a quasi-unique topographical measurement project, and is configured with the measurement values, including a radius value R which defines an area, a start point value X and a stop point value Y for positioning the screw carriage, a speed value S for speed of advancement of the screw carriage, an interval value I for measurement interval, and a points value N for points of measurement per measurement interval.
FILED	Friday, February 19, 2016
APPL NO	15/047806
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 1/02 (20130101) G01C 11/00 (20130101) G01C 15/00 (20130101) G01C 15/002 (20130101) G01C 15/06 (20130101) Original (OR) Class Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/30 (20130101) G01F 23/66 (20130101) Optical Elements, Systems, or Apparatus G02B 27/1093 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Non-Profit Organization (NPO)

09803243 — Biomarkers for diagnosis of stroke and its causes

US 09803243	Sharp et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) Non-Profit Organization (NPO) American Heart Association (AHA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Frank Sharp (Davis, California); Boryana Stamova (Davis, California); Glen C. Jickling (Sacramento, California)
ABSTRACT	The present invention provides compositions and methods for the diagnosis of the occurrence and cause of stroke.
FILED	Sunday, March 13, 2016
APPL NO	15/068600
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/50 (20130101) G01N 2800/2871 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

09807519 — Method and apparatus for analyzing and visualizing the performance of frequency lowering hearing aids

US 09807519	Brungart
FUNDED BY
APPLICANT(S)	Douglas S. Brungart (Rockville, Maryland)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of Defense (Washington, District of Columbia)
INVENTOR(S)	Douglas S. Brungart (Rockville, Maryland)
ABSTRACT	A method of analyzing performance of frequency lowering hearing aids. The method includes generating a sequentially of noise signals and transmitting acoustical sounds from a sound output device in response to the sequence of noise signals. A sound input device records the acoustical sounds and saves as a first device data. The sound input device with a frequency lowering hearing aid records the acoustical sounds and save as a second device data. The second device data is compared to the first device data and, in response to the comparison, at least one function of the frequency lowering hearing aid is optionally adjusted.
FILED	Monday, August 11, 2014
APPL NO	14/456252
ART UNIT	2655 — Digital Audio Data Processing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/12 (20130101) A61B 5/121 (20130101) A61B 5/04845 (20130101) A61B 5/6817 (20130101) A61B 5/7257 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/30 (20130101) Original (OR) Class H04R 25/353 (20130101) H04R 25/505 (20130101) H04R 29/004 (20130101) H04R 29/008 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 31, 2017.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20171031.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital