FedInvent™ Patents
Patent Details for Tuesday, March 27, 2018
This page was updated on Monday, March 27, 2023 at 05:30 AM GMT
Department of Health and Human Services (HHS)
US 09924863 | Buckland et al. |
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FUNDED BY |
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APPLICANT(S) | Bioptigen, Inc. (Morrisville, North Carolina) |
ASSIGNEE(S) | Bioptigen, Inc. (Morrisville, North Carolina) |
INVENTOR(S) | Eric L. Buckland (Hickory, North Carolina); Nestor O. Farmiga (Rochester, New York); Robert H. Hart (Cary, North Carolina); Andrew Murnan (Saratoga Springs, New York); Christopher Saxer (Chapel Hill, North Carolina) |
ABSTRACT | Some embodiments of the present inventive concept provide optical coherence tomography (OCT) systems for integration with a microscope. The OCT system includes a sample arm coupled to the imaging path of a microscope. The sample arm includes an input beam zoom assembly including at least two movable lenses configured to provide shape control for an OCT signal beam; a scan assembly including at least one scanning mirror and configured for telecentric scanning of the OCT signal beam; and a beam expander configured to set the OCT signal beam diameter incident on the microscope objective. The shape control includes separable controls for numerical aperture and focal position of the imaged OCT beam. |
FILED | Thursday, August 25, 2016 |
APPL NO | 15/246578 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/13 (20130101) A61B 3/102 (20130101) Original (OR) Class A61B 3/132 (20130101) A61B 5/0066 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02039 (20130101) G01B 9/02091 (20130101) Optical Elements, Systems, or Apparatus G02B 1/11 (20130101) G02B 21/02 (20130101) G02B 21/006 (20130101) G02B 21/0012 (20130101) G02B 21/025 (20130101) G02B 21/0048 (20130101) G02B 27/0031 (20130101) G02B 27/141 (20130101) G02B 27/0955 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09924867 | Abramoff et al. |
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FUNDED BY |
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APPLICANT(S) | Michael D. Abramoff (University Heights, Iowa); Melndert Niemeijer (Iowa City, Iowa); Xiayu Xu (Iowa City, Iowa); Milan Sonka (Coralville, Iowa); Joseph M. Reinhardt (Iowa City, Iowa) |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); The United States of America, as represented by the Secretary of the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Michael D. Abramoff (University Heights, Iowa); Melndert Niemeijer (Iowa City, Iowa); Xiayu Xu (Iowa City, Iowa); Milan Sonka (Coralville, Iowa); Joseph M. Reinhardt (Iowa City, Iowa) |
ABSTRACT | The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct. |
FILED | Friday, January 20, 2012 |
APPL NO | 13/355386 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) Original (OR) Class A61B 3/0016 (20130101) A61B 3/0058 (20130101) A61B 3/1225 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09924883 | Cui et al. |
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APPLICANT(S) | Xinyan T. Cui (Wexford, Pennsylvania); Carl F. Lagenaur (Pittsburgh, Pennsylvania); Erdrin Azemi (Sunnyvale, California); Noah R. Snyder (Glenshaw, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Xinyan T. Cui (Wexford, Pennsylvania); Carl F. Lagenaur (Pittsburgh, Pennsylvania); Erdrin Azemi (Sunnyvale, California); Noah R. Snyder (Glenshaw, Pennsylvania) |
ABSTRACT | Disclosed herein are neural probes comprising an L1 polypeptide functional fragment thereof on the exterior surface of the probe, devices including such electrodes, and methods of their use. The disclosed embodiments are useful, for example, for in methods of recording and/or stimulating neural signals in a subject. |
FILED | Friday, June 27, 2014 |
APPL NO | 14/317271 |
ART UNIT | 3739 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/688 (20130101) A61B 5/04001 (20130101) Original (OR) Class A61B 5/6868 (20130101) A61B 2562/125 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0526 (20130101) A61N 1/0529 (20130101) A61N 1/0534 (20130101) A61N 1/0551 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925034 | Pathak |
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FUNDED BY |
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APPLICANT(S) | VERILY LIFE SCIENCES LLC (Mountain View, California) |
ASSIGNEE(S) | Verily Life Sciences LLC (Mountain View, California) |
INVENTOR(S) | Anupam Pathak (Los Altos Hills, California) |
ABSTRACT | A system and method for stabilizing unintentional muscle movements are disclosed. In a first aspect, a non-contact sensing system comprises a stabilization unit, at least one non-contact position sensor coupled to the stabilization unit, and a processing unit coupled to the at least one non-contact position sensor, wherein the processing unit transmits motion commands to the stabilization unit to cancel unintentional muscle movements. In a second aspect, the method comprises a processing unit of a non-contact sensing system receiving position data of a stabilization unit that is detected by at least one non-contact position sensor and filtering the position data to identify the unintentional muscle movements. The method includes modeling the position data to create a system model and determining motor commands based upon the system model to cancel the unintentional muscle movements. |
FILED | Wednesday, July 03, 2013 |
APPL NO | 13/935387 |
ART UNIT | 3738 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1101 (20130101) A61B 5/4082 (20130101) A61B 5/4836 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) Original (OR) Class A61F 4/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925172 | Baraban |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Scott C. Baraban (Novato, California) |
ABSTRACT | Provided, inter alia, are methods for treating an epilepsy disorder using clemizole, a clemizole analog, or pharmaceutical salts thereof. |
FILED | Thursday, February 18, 2016 |
APPL NO | 15/047254 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/20 (20130101) A61K 31/20 (20130101) A61K 31/27 (20130101) A61K 31/27 (20130101) A61K 31/36 (20130101) A61K 31/55 (20130101) A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/195 (20130101) A61K 31/195 (20130101) A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/357 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/473 (20130101) A61K 31/473 (20130101) A61K 31/551 (20130101) A61K 31/551 (20130101) A61K 31/4015 (20130101) A61K 31/4166 (20130101) A61K 31/4184 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/5513 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 33/00 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925180 | Hergenrother et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); The Board of Regents of the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Paul J. Hergenrother (Champaign, Illinois); David A. Boothman (Dallas, Texas); Joseph S. Bair (Albany, California); Rahul Palchaudhuri (Cambridge, Massachusetts); Elizabeth I. Parkinson (Champaign, Illinois) |
ABSTRACT | Compositions comprising Formula (I) can be selectively lethal toward a variety of different cancer cell types. The compositions are useful for the management, treatment, control, or adjunct treatment of diseases, where the selective lethality is beneficial in chemotherapeutic therapy. |
FILED | Thursday, March 09, 2017 |
APPL NO | 15/454377 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925184 | Zisman |
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APPLICANT(S) | Pulmokine, Inc. (Rensselaer, New York); GILEAD SCIENCES, INC. (Foster City, California) |
ASSIGNEE(S) | Pulmokine, Inc. (Rensselaer, New York); Gilead Sciences, Inc. (Foster City, California) |
INVENTOR(S) | Lawrence S Zisman (Rensselaer, New York) |
ABSTRACT | Disclosed herein are compounds, compositions, and methods for preventing and treating proliferative diseases associated with aberrant receptor tyrosine kinase (RTK) activity. The therapeutic indications described herein more specifically relate to the non-selective inhibition of RTKs associated with vascular and pulmonary disorders. |
FILED | Friday, October 10, 2014 |
APPL NO | 15/028347 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0075 (20130101) A61K 9/1617 (20130101) A61K 31/497 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/4965 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925190 | Smithgall |
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APPLICANT(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Thomas E. Smithgall (Wexford, Pennsylvania) |
ABSTRACT | A method of treating HIV in a subject, comprising administering to a subject in need thereof a therapeutically effective amount of a compound having a general Formula 1, or a pharmaceutically acceptable salt or ester thereof: wherein R1 is selected from H, optionally-substituted aryl, optionally-substituted heteroaryl, or optionally-substituted aliphatic; each R2 is independently selected from H, halogen, cyano, thioether, oxo, optionally-substituted amino, optionally-substituted heteroaryl, optionally-substituted aryl, or optionally-substituted aliphatic; a is 3 to 7; and the ring designates a heterocyclic or heteroaryl structure. |
FILED | Thursday, February 11, 2016 |
APPL NO | 15/042069 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) A61K 31/501 (20130101) A61K 31/513 (20130101) Original (OR) Class A61K 31/4155 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925202 | Yu et al. |
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APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
INVENTOR(S) | Jane Yu (Cincinnati, Ohio); Chenggang Li (Maineville, Ohio) |
ABSTRACT | Embodiments disclosed herein provide compositions and methods for treating lymphangioleiomyomatosis (LAM) comprising inhibiting COX overexpression and prostaglandin over production by administering at least one COX inhibitor and/or prostaglandin biosynthetic pathway inhibitors. Lymphangioleiomyomatosis (LAM) is a rare lung disease. Some LAM occurances are associated with mutations in the tuberous sclerosis complex (TSC) locus. LAM occurs almost exclusively in women, usually of childbearing age. |
FILED | Tuesday, March 04, 2014 |
APPL NO | 14/771817 |
ART UNIT | 1673 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 31/42 (20130101) A61K 31/42 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/365 (20130101) A61K 31/365 (20130101) A61K 31/405 (20130101) A61K 31/405 (20130101) A61K 31/415 (20130101) A61K 31/415 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/616 (20130101) Original (OR) Class A61K 31/616 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925209 | DeAngelis |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma) |
INVENTOR(S) | Paul L. DeAngelis (Edmond, Oklahoma) |
ABSTRACT | Compositions containing conjugates of heparosan polymer with at least one drug are disclosed, along with methods of production and use thereof. |
FILED | Friday, November 07, 2014 |
APPL NO | 14/536003 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Original (OR) Class A61K 38/21 (20130101) A61K 38/22 (20130101) A61K 38/27 (20130101) A61K 38/28 (20130101) A61K 38/50 (20130101) A61K 38/193 (20130101) A61K 39/395 (20130101) A61K 47/61 (20170801) A61K 2039/505 (20130101) Enzymes C12Y 305/01001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925213 | Gellman et al. |
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APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
INVENTOR(S) | Samuel H. Gellman (Madison, Wisconsin); Shannon S. Stahl (Madison, Wisconsin); Brendan P. Mowery (San Marcos, California); Annelise Barron (Palo Alto, California); Michelle Dohm (Palos Park, Illinois) |
ABSTRACT | Non-natural oligomers have recently shown promise as functional analogs of lung surfactant proteins B and C (SP-B and SP-C), two helical and amphiphilic proteins that are critical for normal respiration. The generation of non-natural mimics of SP-B and SP-C has previously been restricted to step-by-step, sequence-specific synthesis, which results in discrete oligomers that are intended to manifest specific structural attributes. Presented herein an alternative approach to SP-B mimicry that is based on sequence-random copolymers containing cationic and lipophilic subunits. These materials, members of the nylon-3 family, are prepared by ring-opening polymerization of β-lactams. The best of the nylon-3 polymers display promising in vitro surfactant activities in a mixed lipid film. Pulsating bubble surfactometry data indicate that films containing the most surface-active polymers attain adsorptive and dynamic-cycling properties that surpass those of discrete peptides intended to mimic SP-B. Attachment of an N-terminal octadecanoyl unit to the nylon-3 copolymers affords further improvements by reducing the percent surface area compression to reach low minimum surface tension. |
FILED | Friday, May 01, 2015 |
APPL NO | 14/701775 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0082 (20130101) A61K 31/785 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925222 | Mani et al. |
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APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (Bronx, New York) |
ASSIGNEE(S) | Albert Einstein College of Medicine, Inc. (Bronx, New York) |
INVENTOR(S) | Sridhar Mani (Riverdale, New York); Subhajit Mukherjee (Bronx, New York) |
ABSTRACT | Methods are disclosed for treating and preventing gut barrier dysfunction or an illness associated with gut barrier dysfunction in a subject comprising administering to the subject bacterium that produce an indole or an indole metabolite and for identifying compounds and bacteria for use in treatment and prevention of gut barrier dysfunction or an illness associated with gut barrier dysfunction. |
FILED | Wednesday, June 03, 2015 |
APPL NO | 14/729211 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 2035/115 (20130101) Heterocyclic Compounds C07D 211/56 (20130101) C07D 211/92 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Electric Digital Data Processing G06F 19/345 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/145555 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925223 | Kaznessis et al. |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Yiannis J. Kaznessis (New Brighton, Minnesota); Katherine G. Volzing (Princeton, New Jersey); Juan Borrero Del Pino (Cork, Ireland); Gary Dunny (Minneapolis, Minnesota) |
ABSTRACT | Provided herein are genetically modified microbes. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide comprising a pheromone-responsive region. In one embodiment, the pheromone-responsive region is derived from a conjugative plasmid from a member of the genus Enterococcus spp. The pheromone-responsive region includes a pheromone-responsive promoter and an operably linked coding region encoding an antimicrobial peptide. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide comprising a promoter and an operably linked coding sequence encoding an antimicrobial peptide, where expression of the coding region is controlled by a modulator polypeptide and is altered by a modulating agent, and where the coding region encodes an antimicrobial peptide. Also provided herein are methods of using the genetically modified microbes, including methods for inhibiting growth of an Enterococcus spp., a pathogenic E. coli, or a pathogenic Salmonella spp., for treating a subject, and for modifying a subject's gastrointestinal microflora. |
FILED | Wednesday, September 25, 2013 |
APPL NO | 14/431044 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/744 (20130101) Original (OR) Class A61K 38/10 (20130101) A61K 38/16 (20130101) A61K 2035/11 (20130101) Peptides C07K 7/08 (20130101) C07K 14/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/746 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925230 | Budd |
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FUNDED BY |
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APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
ASSIGNEE(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
INVENTOR(S) | Ralph C. Budd (Hinesburg, Vermont) |
ABSTRACT | Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject. |
FILED | Wednesday, July 22, 2015 |
APPL NO | 14/806047 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 35/15 (20130101) A61K 38/06 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/0225 (20130101) A61K 2039/6006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925237 | Healy et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Kevin Edward Healy (Moraga, California); Samuel T. Wall (Oslo, Norway); Krishanu Saha (Cambridge, Massachusetts); David V. Schaffer (Danville, California) |
ABSTRACT | The present invention provides polypeptide-polymer conjugates. A subject polypeptide-polymer conjugate is useful in a variety of applications, which are also provided. |
FILED | Tuesday, July 19, 2016 |
APPL NO | 15/214398 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class A61K 47/4823 (20130101) A61K 47/48176 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925241 | Suh et al. |
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APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
INVENTOR(S) | Jae Myoung Suh (San Diego, California); Michael Downes (San Diego, California); Ronald M. Evans (La Jolla, California); Annette Atkins (San Diego, California); Ruth T. Yu (La Jolla, California) |
ABSTRACT | The present disclosure provides FGF1 mutant proteins, such as those having an N-terminal deletion, point mutation(s), or combinations thereof, which can reduce blood glucose in a mammal. Such mutant FGF1 proteins can be part of a chimeric protein that includes a β-Klotho-binding protein, an FGFR1c-binding protein, a β-Klotho-binding protein and a FGFR1c-binding protein, a C-terminal region from FGF19 or FGF21. In some examples, mutant FGF1 proteins have reduced mitogenic activity. Also provided are nucleic acid molecules that encode such proteins, and vectors and cells that include such nucleic acids. Methods of using the disclosed molecules to reduce blood glucose levels are also provided. |
FILED | Tuesday, October 21, 2014 |
APPL NO | 14/520178 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/421 (20130101) A61K 31/421 (20130101) A61K 31/422 (20130101) A61K 31/422 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/7088 (20130101) A61K 38/1825 (20130101) Original (OR) Class A61K 38/1825 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/501 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925243 | Suh et al. |
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APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
INVENTOR(S) | Jae Myoung Suh (San Diego, California); Michael Downes (San Diego, California); Ronald M. Evans (La Jolla, California); Annette Atkins (San Diego, California); Senyon Choe (Solana Beach, California); Witek Kwiatkowski (San Diego, California) |
ABSTRACT | The present disclosure provides chimeric proteins having an N-terminus coupled to a C-terminus, wherein the N-terminus comprises an N-terminal portion of fibroblast growth factor (FGF) 2 and the C-terminus comprises a portion of an FGF1 protein, wherein the chimeric protein comprises at least 95% sequence identity to SEQ ID NO: 9, 10, 11, 12 or 13. Also provided are nucleic acid molecules that encode such proteins, and vectors and cells that include such nucleic acids. Methods of using the disclosed molecules to reduce blood glucose levels are also provided. |
FILED | Wednesday, April 06, 2016 |
APPL NO | 15/092481 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1825 (20130101) Original (OR) Class A61K 45/06 (20130101) Peptides C07K 14/50 (20130101) C07K 14/501 (20130101) C07K 14/503 (20130101) C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925248 | Khalili et al. |
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FUNDED BY |
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APPLICANT(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
INVENTOR(S) | Kamel Khalili (Bala Cynwyd, Pennsylvania); Wenhui Hu (Cherry Hill, New Jersey) |
ABSTRACT | A method of inactivating a proviral DNA integrated into the genome of a host cell latently infected with a retrovirus by treating the host cell with a composition comprising a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated endonuclease, and two or more different guide RNAs (gRNAs), wherein each of the at least two gRNAs is complementary to a different target nucleic acid sequence in a long terminal repeat (LTR) in the proviral DNA, and inactivating the proviral DNA. A composition for use in inactivating a proviral DNA integrated into the genome of a host cell latently infected with a retrovirus including isolated nucleic acid sequences comprising a CRISPR-associated endonuclease and a guide RNA, wherein the guide RNA is complementary to a target sequence in a human immunodeficiency virus. |
FILED | Friday, August 29, 2014 |
APPL NO | 14/838057 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 35/12 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2320/30 (20130101) C12N 2740/16063 (20130101) Enzymes C12Y 301/21 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925251 | Akopian et al. |
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FUNDED BY |
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APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Tatos Akopian (West Roxbury, Massachusetts); Olga Kandror (Newton, Massachusetts); Alfred Lewis Goldberg (Brookline, Massachusetts); Ravikiran M. Raju (Cambridge, Massachusetts); Meera Unnikrishnan (Sienna, Italy); Eric J. Rubin (Waban, Massachusetts) |
ABSTRACT | The technology described herein relates to treatments for tuberculosis which target the ClpP1P2 protease complex, including ClpC1. Further embodiments relate to assays and screens for modulators of the ClpP1P2 protease complex, including ClpC1. |
FILED | Friday, October 19, 2012 |
APPL NO | 14/352440 |
ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/055 (20130101) A61K 31/055 (20130101) A61K 31/70 (20130101) A61K 38/04 (20130101) A61K 38/12 (20130101) A61K 38/15 (20130101) A61K 38/15 (20130101) A61K 38/55 (20130101) Original (OR) Class A61K 38/482 (20130101) A61K 38/482 (20130101) A61K 39/04 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 5/08 (20130101) C07K 5/0821 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Enzymes C12Y 304/21092 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925257 | Campos-Neto et al. |
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FUNDED BY |
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APPLICANT(S) | The Forsyth Institute (Cambridge, Massachusetts) |
ASSIGNEE(S) | Forsyth Dental Infirmary for Children (Cambridge, Massachusetts) |
INVENTOR(S) | Antonio Campos-Neto (Westborough, Massachusetts); Mark Cayabyab (San Jose, California); Margaret Duncan (Brookline, Massachusetts) |
ABSTRACT | The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed non-pathogenic, commensal bacteria that can express a nucleic acid molecule of a foreign polypeptide, wherein the nucleic acid molecule that encodes the foreign polypeptide is stably integrated into genomic DNA of the bacteria. The foreign polypeptide includes a vaccine antigen that elicits an immunogenic response, an inhibitor of a pathogen, or an immune booster or modulator. |
FILED | Friday, January 23, 2015 |
APPL NO | 14/604215 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/08 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/58 (20130101) A61K 2039/523 (20130101) A61K 2039/541 (20130101) A61K 2039/545 (20130101) Peptides C07K 14/005 (20130101) C07K 14/33 (20130101) C07K 14/35 (20130101) C07K 14/315 (20130101) C07K 2319/02 (20130101) C07K 2319/21 (20130101) C07K 2319/40 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) C12N 2740/15022 (20130101) C12N 2740/15033 (20130101) C12N 2740/16033 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925270 | Maynard et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Heather D. Maynard (Los Angeles, California); Thi Nguyen (Reseda, California) |
ABSTRACT | A heparin mimicking polymer, its conjugate with bFGF, and method of making and using the same are disclosed. In particular, described herein are conjugates of biologic agents (e.g., bFGF) and heparin mimicking polymers having superior stability while retaining full native activity after a variety of stressors. |
FILED | Wednesday, November 28, 2012 |
APPL NO | 14/361167 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/795 (20130101) A61K 38/1825 (20130101) A61K 47/48176 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925271 | Naleway et al. |
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FUNDED BY |
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APPLICANT(S) | Marker Gene Technologies, Inc. (Eugene, Oregon) |
ASSIGNEE(S) | Marker Gene Technologies, Inc (Eugene, Oregon) |
INVENTOR(S) | John Joseph Naleway (Eugene, Oregon); Fiona Karen Harlan (Eugene, Oregon); Jason Scott Lusk (Eugene, Oregon) |
ABSTRACT | The present invention relates to the preparation and use of therapeutic compounds for the treatment of diseases at specific subcellular target areas such as specific cellular organelles. In particular, the therapeutic compounds of the invention are specific for modifying enzyme activity within targeted organelles or structures of cells and tissues. Subcellular organelles and structures that may be specifically targeted by compounds of the present invention include lysosomes, autophagasomes, the endoplasmic reticulum, the Golgi complex, peroxisomes, the nucleus, membranes and the mitochondria. |
FILED | Monday, April 03, 2017 |
APPL NO | 15/477569 |
ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/445 (20130101) A61K 47/64 (20170801) A61K 47/645 (20170801) A61K 47/48246 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925281 | Steinmetz et al. |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Nicole F. Steinmetz (Cleveland, Ohio); Michael Bruckman (Cleveland, Ohio); Lauren Randolph (State College, Pennsylvania) |
ABSTRACT | An imaging nanoparticle comprising a plant virus particle having an interior surface and an exterior surface, an imaging agent that is linked to the interior and/or exterior surface, and a layer of biocompatible mineral such as silica coated over the exterior surface, is described. The imaging nanoparticle can be used in method of generating an image of a tissue region of a subject, by administering to the subject a diagnostically effective amount of an imaging nanoparticle and generating an image of the tissue region of the subject to which the imaging nanoparticle has been distributed. |
FILED | Wednesday, August 05, 2015 |
APPL NO | 14/818812 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/085 (20130101) A61K 49/108 (20130101) A61K 49/1896 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925283 | Weichert et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Jamey Paul Weichert (Fitchburg, Wisconsin); Chorom Pak (Madison, Wisconsin); Benjamin Titz (Madison, Wisconsin); Fotis Asimakopoulos (Madison, Wisconsin); Roberta Marino (Cordova, Tennessee); Mario Otto (Fitchburg, Wisconsin); Kevin R. Kozak (Janesville, Wisconsin) |
ABSTRACT | It is disclosed herein that that certain alkylphosphocholine analogs are preferentially taken up by multiple myeloma tumor cells. The alkylphophocholine analogs are compounds having the formula: or salts thereof, wherein n is an integer from 12 to 24; and R2 is —N+H3, —N+H2X, —N+HX2, or —N+HX3, wherein each X is independently —CH3 or —C2H5. The compounds can be used to treat multiple myeloma or to detect multiple myeloma. In therapeutic treatment, R1 includes a radionuclide that locally delivers therapeutic dosages of radiation to the multiple myeloma tumors cells that preferentially take up the compound. In detection/imaging applications, R1 includes a detection moiety, such as a fluorophore or a radiolabel. |
FILED | Monday, April 11, 2016 |
APPL NO | 15/095641 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0489 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/582 (20130101) G01N 33/57407 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925297 | Grunlan et al. |
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FUNDED BY |
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APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
INVENTOR(S) | Melissa A. Grunlan (College Station, Texas); Dawei Zhang (Beijing, China PRC); Cody A. Schoener (Midland, Michigan); William B. Saunders (College Station, Texas) |
ABSTRACT | A method of making a shape memory polymer (SMP) tissue scaffold includes forming a salt template and adding a macromer solution to the salt template. The macromer solution may include a photoinitiator solution. The method includes drying the SMP scaffold and leaching salt from the SMP scaffold. A coating is then applied to the SMP scaffold. The coating may be applied either before or after heating the SMP scaffold. |
FILED | Sunday, July 24, 2016 |
APPL NO | 15/218043 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/18 (20130101) A61L 27/56 (20130101) A61L 27/446 (20130101) A61L 27/446 (20130101) A61L 2400/08 (20130101) A61L 2400/16 (20130101) A61L 2430/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 2035/0827 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0056 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7532 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925299 | Kaplan et al. |
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FUNDED BY |
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APPLICANT(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
ASSIGNEE(S) | Tufts University (Medord, Massachusetts) |
INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Tim Jia-Ching Lo (Taoyuan, Taiwan); Stephanie McNamara (North Attleboro, Massachusetts) |
ABSTRACT | The disclosure provides ceramic materials comprising calcium phosphate material and silk and processes and methods for preparing and uses thereof. |
FILED | Monday, October 28, 2013 |
APPL NO | 14/437881 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/12 (20130101) A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3821 (20130101) A61L 2300/412 (20130101) A61L 2430/02 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925301 | Kaplan et al. |
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FUNDED BY |
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APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Biman B. Mandal (Kolkata, India) |
ABSTRACT | Provided herein relates to methods for preparing micron range silk fibers (or silk microfibers) and compositions comprising a micron range silk fiber (or a silk microfiber). The micron range silk fibers (or silk microfibers) can be used in various applications ranging from fillers in cosmetics to reinforcement materials to design high strength composites, e.g., reinforced scaffolds. In some embodiments, the silk microfiber-reinforced scaffolds can be used for bone graft applications because of their high compressive strength. |
FILED | Friday, April 05, 2013 |
APPL NO | 14/390362 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/365 (20130101) A61L 27/3604 (20130101) Original (OR) Class A61L 27/3687 (20130101) A61L 27/3821 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/02 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/045 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/02 (20130101) Chemical Treatment of Natural Filamentary or Fibrous Material to Obtain Filaments or Fibres for Spinning; Carbonising Rags to Recover Animal Fibres D01C 3/00 (20130101) Finishing or Dressing of Filaments, Yarns, Threads, Cords, Ropes or the Like D02J 1/00 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/4266 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/36 (20130101) D06M 2101/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925373 | Nirenberg |
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FUNDED BY |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Sheila Nirenberg (New York, New York) |
ABSTRACT | A method improving or restoring neural function in a mammalian subject in need thereof, the method including: using an input receiver to record an input signal generated by a first set of nerve cells; using an encoder unit including a set of encoders to generate a set of coded outputs in response to the input signal; using the encoded outputs to drive an output generator; and using an output generator to activate a second set of nerve cells wherein the second set of nerve cells is separated from the first set of nerve cells by impaired set of signaling cells. In some embodiments, the second set of nerve cells produces a response that is substantially the same as the response in an unimpaired subject. |
FILED | Thursday, March 17, 2016 |
APPL NO | 15/073002 |
ART UNIT | 3766 — Printing/Measuring and Testing |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0079 (20130101) A61F 2009/00863 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 1/0543 (20130101) A61N 1/3605 (20130101) A61N 1/36003 (20130101) Original (OR) Class A61N 1/36036 (20170801) A61N 1/36046 (20130101) A61N 1/36067 (20130101) A61N 1/36139 (20130101) A61N 5/0622 (20130101) A61N 2005/063 (20130101) A61N 2005/0605 (20130101) A61N 2005/0652 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925574 | Christenson et al. |
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FUNDED BY |
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APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
INVENTOR(S) | Mark Christenson (Lincoln, Nebraska); Steven Douglas Comfort (Lincoln, Nebraska) |
ABSTRACT | In one implementation, a direct-push oxidant candle apparatus for the treatment of contaminated groundwater through direct-push installation methods includes: a drive tip positioned at a bottom end of the apparatus, the drive tip having one or more front surfaces that are shaped to create a bore as force is applied to an opposite base surface of the drive tip; a structural pathway that is connected to and extend upwardly from the base surface of the drive tip; one or more oxidant delivery devices that are enclosed within the structural pathway; and one or more fluid supply lines that extend from one or more locations outside of the bore and that terminate at or near a bottom end of the structural pathway so that fluid supplied through the fluid supply lines travels through the structural pathway and along the one or more oxidant delivery devices. |
FILED | Thursday, March 31, 2016 |
APPL NO | 15/086532 |
ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Reclamation of Contaminated Soil B09C 1/002 (20130101) Original (OR) Class B09C 1/08 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 2103/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926271 | Petrukhin et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Albany, New York); Graham Johnson (Sanbornton, New Hampshire); Nicoleta Dobri (New York, New York); Emily Freeman (Albany, New York); Ping Chen (Albany, New York); Michael Conlon (Albany, New York); Lei Zhu (Albany, New York) |
ABSTRACT | The present invention provides Octahydrocyclopentapyrrole compounds having the structure: (structurally represented) wherein psi is absent or present, and when present is a bond; R1, R2, R3, R4, and R5 are each independently H, halogen, CF, or C1-C4 alkyl; R6 is absent or present, and when present is H, OH, or halogen; A is absent or present, and when present is C(O) or C(O)NH; B is substituted or unsubstituted monocycle, bicycle, heteromonocycle, heterobicycle, benzyl, CO2H or (C1-C4 alkyl)-CO2H, wherein when B is CO2H, then A is present and is C(O); and when psi is present, then R6 is absent and when psi is absent, then R6 is present, or a pharmaceutically acceptable salt thereof, for treatment of diseases characterized by excessive lipofuscin accumulation in the retina. |
FILED | Monday, March 13, 2017 |
APPL NO | 15/457821 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 209/52 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 403/04 (20130101) C07D 403/06 (20130101) C07D 403/12 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 498/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926275 | Thakur et al. |
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FUNDED BY |
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APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Ganeshsingh Arjunsingh Thakur (Watertown, Massachusetts); Ritesh B. Tichkule (Somerville, Massachusetts); Pushkar Mukund Kulkarni (Boston, Massachusetts); Abhijit Raghunath Kulkarni (Boston, Massachusetts) |
ABSTRACT | The present technology relates to compounds and compositions of Formulas I, II, VII, and VIII, and methods using such compounds. The compounds and compositions described herein may be used in the treatment or prophylaxis of addiction, metabolic syndrome, obesity, and/or a CB1 receptor-mediated disorder. |
FILED | Friday, August 22, 2014 |
APPL NO | 14/911959 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 213/40 (20130101) C07D 213/74 (20130101) Original (OR) Class C07D 295/135 (20130101) C07D 401/12 (20130101) C07D 405/12 (20130101) C07D 413/10 (20130101) C07D 413/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926290 | Bushweller et al. |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | John H. Bushweller (Crozet, Virginia); Jolanta Grembecka (Ann Arbor, Michigan); Anuradha Illendula (Crozet, Virginia); Lauren Mishra (Tucson, Arizona) |
ABSTRACT | This invention describes the development of targeted small molecule inhibitors of the inv(16) fusion, the causative agent in ˜12% of acute myeloid leukemia (AML). The inv(16) fusion results in expression of the CBFβ-SMMHC fusion protein in the blood cells of afflicted patients. The present invention provides compounds which inhibit the function of both CBFβ and the CBFβ-SMMHC fusion. These compounds block the growth of an inv(16) leukemia cell line as well as increase its apoptosis, while showing minimal effects against non inv(16) cell lines. As a mechanism to develop inhibitors with selectivity for the CBFβ-SMMHC fusion protein, the present invention further provides dimeric derivatives of these compounds which show both increased potency as well as selectivity for CBFβ-SMMHC. These compounds show potent inhibition of an inv(16) leukemia cell line with minimal effects on non inv(16) cell lines. Analysis of the pharmacokinetics of the developed compounds has made it possible to improve the lifetime of the compound in the plasma of mice to a level commensurate with long-term treatment. |
FILED | Monday, December 14, 2015 |
APPL NO | 14/967568 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 235/18 (20130101) C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 405/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926291 | Ouerfelli et al. |
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FUNDED BY |
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APPLICANT(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
INVENTOR(S) | Ouathek Ouerfelli (Fort Lee, New Jersey); Anna Dilhas (Basel, Switzerland); Guangbin Yang (Forest Hills, New York); Hong Zhao (Rego Park, New York) |
ABSTRACT | A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52. |
FILED | Tuesday, December 06, 2016 |
APPL NO | 15/370093 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 209/36 (20130101) C07C 209/36 (20130101) C07C 211/52 (20130101) C07C 213/08 (20130101) C07C 213/08 (20130101) C07C 217/58 (20130101) C07C 227/18 (20130101) C07C 231/12 (20130101) C07C 253/00 (20130101) C07C 253/00 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 255/46 (20130101) C07C 255/46 (20130101) C07C 2601/04 (20170501) Heterocyclic Compounds C07D 213/61 (20130101) C07D 213/64 (20130101) C07D 213/72 (20130101) C07D 213/74 (20130101) C07D 213/76 (20130101) C07D 213/84 (20130101) C07D 213/643 (20130101) C07D 401/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926293 | Stockwell et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Brent R. Stockwell (New York, New York); Matthew Welsch (New York, New York) |
ABSTRACT | The present invention provides, inter alia, compounds having the structure: wherein R7, R8 and n are as disclosed herein, that selectively bind a RAS protein at two or more sites and methods for their synthesis. Compositions and kits containing the compounds, as well as methods of using the compounds and compositions for ameliorating or treating the effects of a disease associated with altered RAS signaling, such as a cancer, in a subject and methods for effecting cancer cell death are also provided herein. Methods of identifying a multivalent compound which binds selectively to a target protein also are provided herein. |
FILED | Tuesday, March 22, 2016 |
APPL NO | 15/077865 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 209/14 (20130101) C07D 295/108 (20130101) C07D 401/12 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 403/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926306 | Walensky |
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FUNDED BY |
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APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Loren D. Walensky (Newton Centre, Massachusetts) |
ABSTRACT | This disclosure features compounds and pharmaceutically acceptable salts thereof that inhibit MCL-1 and/or BFL-1/A1 and compositions containing the same. This disclosure also features combinations that include one or more of the MCL-1/BFL-1/A1 inhibitor compounds described herein, or a pharmaceutically acceptable salt thereof; and one or more additional therapeutic agents (e.g., one or more chemotherapeutic agents (including small molecule and/or anti-body based chemotherapy and/or radiation); e.g., one or more therapeutic agents that modulate apoptosis; e.g., one or more therapeutic agents that bind to and inhibit anti-apoptotic proteins or modulate them indirectly; e.g., one or more therapeutic agents that bind to and inhibit, or indirectly modulate, anti-apoptotic BCL-2, BCL-XL, BCL-w, MCL-1, and/or BFL-1/A1; e.g., one or more therapeutic agents that directly bind to and inhibit anti-apoptotic BCL-2/BCL-XL; e.g., agents such as ABT-199, ABT-263 and ABT-737; e.g., ABT-737), or (where applicable) a pharmaceutically acceptable salt of the one or more therapeutic agents (as well as compositions containing the same). Also featured are methods of using such compounds, salts, combinations, and compositions, e.g., for the treatment or prevention of diseases, disorders, and conditions associated with deregulated apoptosis of cells (e.g., diseased or damaged cells; e.g., insufficient apoptosis of diseased or damaged cells or reduced apoptosis of diseased or damaged cells). |
FILED | Thursday, March 14, 2013 |
APPL NO | 14/386747 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/428 (20130101) A61K 31/454 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 277/42 (20130101) C07D 277/54 (20130101) C07D 277/56 (20130101) C07D 277/60 (20130101) C07D 417/04 (20130101) C07D 417/12 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926309 | Glenn et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jeffrey S. Glenn (Palo Alto, California); Michael A. Gelman (Stanford, California); Brandon Tavshanjian (San Francisco, California); Kevan Shokat (San Francisco, California); Ingrid Choong (Los Altos, California); Mark Smith (San Francisco, California) |
ABSTRACT | Compounds and methods are provided for the treatment of pathogen infections. In some embodiments, the anti-infective compounds have broad spectrum activity against a variety of infective diseases, where the diseases are caused by pathogens containing a basic amino acid PIP-2 pincer (BAAPP) domain that interacts with phosphatidylinositol 4,5-bisphosphate (PIP-2) to mediate pathogen replication. Also provided are methods of inhibiting a PI4-kinase and methods of inhibiting viral infection. In some embodiments, the compound is a PI4-kinase inhibiting compound that is a 5-aryl-thiazole or a 5-hetereoaryl-thiazole. The subject compounds may be formulated or provided to a subject in combination with a second anti-infective agent, e.g. interferon, ribivarin, and the like. |
FILED | Friday, February 26, 2016 |
APPL NO | 15/055403 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 277/42 (20130101) C07D 277/44 (20130101) C07D 277/46 (20130101) C07D 417/04 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926321 | Sun et al. |
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FUNDED BY |
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APPLICANT(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
INVENTOR(S) | Weilin Sun (Princeton, New Jersey); Tony Taldone (Forest Hills, New York); Pallav Patel (Fresh Meadows, New York); Gabriela Chiosis (New York, New York) |
ABSTRACT | The disclosure relates to Compounds of Formulae (IA) and (IB), and pharmaceutically acceptable salts thereof wherein Z1, Z2, Z3, Xa, Xb, Xc, Xd, Y, X2, and X4 are as defined herein, compositions comprising an effective amount of a Compound of Formula (IA) and/or (IB), and methods to treat or prevent a condition, such cancer which overexpresses Her-kinases, comprising administering to an patient in need thereof a therapeutically effective amount of a Compound of Formula (IA) or (IB). The disclosure further relates to compounds of Formulae (IA) and (IB) in which X2 is a leaving for introducing a radiolabeled atom, such as 124I or 131I and to methods of using such compounds in the preparation of radiolabeled compounds, particularly for use in imaging. |
FILED | Friday, May 20, 2016 |
APPL NO | 15/160293 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) Heterocyclic Compounds C07D 473/34 (20130101) Original (OR) Class C07D 473/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926336 | Burns et al. |
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FUNDED BY |
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APPLICANT(S) | VenatoRx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
ASSIGNEE(S) | VENATORX PHARMACEUTICALS (Malvern, Pennsylvania) |
INVENTOR(S) | Christopher J. Burns (Malvern, Pennsylvania); Denis Daigle (Street, Maryland); Bin Liu (Plainsboro, New Jersey); Randy W. Jackson (Livingston, Montana); Jodie Hamrick (New Holland, Pennsylvania); Daniel McGarry (Malvern, Pennsylvania); Daniel C. Pevear (Downingtown, Pennsylvania); Robert E. Lee Trout (Collegeville, Pennsylvania) |
ABSTRACT | Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
FILED | Friday, August 11, 2017 |
APPL NO | 15/675253 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 45/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926340 | Kraus et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas); Biolog Life Science Institute Forschungslabor und Biochemica-Vertrieb GmbH (Bremen, Germany); Cornell University (Ithaca, New York) |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas); Biolog Life Science Institute Forshungslabor und Biochemica-Vertrieb GmbH (Bremen, Germany); Cornell University (Ithica, New York) |
INVENTOR(S) | W. Lee Kraus (Coppell, Texas); Bryan A. Gibson (Dallas, Texas); Frank Schwede (Bremen, Germany); Hening Lin (Ithaca, New York) |
ABSTRACT | The present disclosure provides NAD analogs of the formula: wherein R1, n, and X1 are defined herein, useful for the identification of PARP target proteins and the amino acid sequence wherein the ribose group is attached to the target protein. Also, provided herein are methods of identifying target protein and amino acid sequences. Additionally, the present disclosure provides methods of identifying DNA sequences associated with specific chromatin proteins. |
FILED | Friday, April 01, 2016 |
APPL NO | 15/088561 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91142 (20130101) G01N 2440/40 (20130101) G01N 2458/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926351 | Schellenberger et al. |
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FUNDED BY |
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APPLICANT(S) | Amunix Operating Inc. (Mountain View, California) |
ASSIGNEE(S) | Amunix Operating Inc. (Mountain View, California) |
INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Los Altos Hills, California); Chia-wei Wang (Santa Clara, California); Benjamin Spink (San Carlos, California); Willem P. Stemmer (Los Gatos, California); Nathan Geething (Natick, Massachusetts); Wayne To (Fremont, California); Jeffrey L. Cleland (San Carlos, California) |
ABSTRACT | The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions. |
FILED | Friday, May 13, 2016 |
APPL NO | 15/154223 |
ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/001 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/61 (20130101) C07K 14/545 (20130101) C07K 14/605 (20130101) C07K 14/745 (20130101) C07K 2319/31 (20130101) C07K 2319/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/644 (20130101) C12N 9/6437 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926353 | Wisniewski et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas M. Wisniewski (Staten Island, New York); Fernando Goni (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Thomas M. Wisniewski (Staten Island, New York); Fernando Goni (New York, New York) |
ABSTRACT | The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease. |
FILED | Monday, July 16, 2012 |
APPL NO | 13/550316 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0056 (20130101) A61K 39/0007 (20130101) A61K 2039/64 (20130101) A61K 2039/523 (20130101) Peptides C07K 14/4711 (20130101) Original (OR) Class C07K 16/18 (20130101) C07K 2317/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2333/4709 (20130101) G01N 2800/28 (20130101) G01N 2800/2821 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09926354 — Amyloid precursor protein (APP) based Ã#-secretase inhibitor peptides, and methods of use
US 09926354 | Tan et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
INVENTOR(S) | Jun Tan (Tampa, Florida); Brian Nelson Giunta (Tampa, Florida); Song Li (Tampa, Florida); Huayan Hou (Tampa, Florida); Paul R. Sanberg (Spring Hill, Florida) |
ABSTRACT | The present invention provides fusion peptides, compositions, methods and kits for treating, reducing the risk of, lessening the severity of, preventing, or delaying the onset of amyloid-related disorders, such as Alzheimer's disease and HIV associated neurocognitive impairment. |
FILED | Friday, January 09, 2015 |
APPL NO | 15/107383 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) Peptides C07K 14/4711 (20130101) Original (OR) Class C07K 2319/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926355 | Mohammadi et al. |
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FUNDED BY |
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APPLICANT(S) | New York University (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York) |
ABSTRACT | The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and the C-terminus includes a C-terminal portion of an FGF21 molecule. The portion of the paracrine FGF is modified to decrease binding affinity for heparin and/or heparan sulfate compared to the portion without the modification. The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention. |
FILED | Monday, October 10, 2016 |
APPL NO | 15/289447 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 38/1825 (20130101) A61K 38/1825 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class C07K 14/501 (20130101) C07K 14/503 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/50 (20130101) G01N 2500/02 (20130101) G01N 2800/042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926356 | Mohammadi et al. |
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FUNDED BY |
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APPLICANT(S) | New York University (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York) |
ABSTRACT | The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and the C-terminus includes a C-terminal portion of an FGF19 molecule. The portion of the paracrine FGF is modified to decrease binding affinity for heparin and/or heparan sulfate compared to the portion without the modification. The present invention also relates to pharmaceutical compositions including chimeric proteins according to the present invention, methods for treating a subject suffering from diabetes, obesity, or metabolic syndrome, and methods of screening for compounds with enhanced binding affinity for the βKlotho-FGF receptor complex involving the use of chimeric proteins of the present invention. |
FILED | Monday, October 10, 2016 |
APPL NO | 15/289544 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1825 (20130101) A61K 45/06 (20130101) Peptides C07K 14/50 (20130101) Original (OR) Class C07K 14/501 (20130101) C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926359 | Gross et al. |
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FUNDED BY |
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APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Robert E. Gross (Decatur, Georgia); Nealan G. Laxpati (Atlanta, Georgia); Jack Tung (Duluth, Georgia); Ken Berglund (Kennesaw, Georgia) |
ABSTRACT | This disclosure relates to recombinant proteins, vectors, and methods of treating neurological conditions by exposing neurons to an opsin and luciferase in the presence of a luciferin. In certain embodiments, the disclosure relates to treating or preventing epilepsy or seizures comprising administering an effective amount of a vector that encodes an opsin and luciferase in combination with a luciferin to a subject in need thereof. |
FILED | Friday, October 31, 2014 |
APPL NO | 14/529539 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) Enzymes C12Y 113/12005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926360 | Burrows et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as represented by the Deparment of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Gregory G. Burrows (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon) |
ABSTRACT | The present invention provides, in particular embodiments, for modified recombinant T cell receptor (TCR) ligands (RTLs) comprising a MHC class I or MHC class II component. The modified RTLs have redesigned surface features that preclude or reduce aggregation, wherein the modified molecules retain the ability to bind Ag-peptides, target antigen-specific T cells, inhibit T cell proliferation in an Ag-specific manner and have utility to treat, inter alia, autoimmune disease and other conditions mediated by antigen-specific T cells in vivo. |
FILED | Thursday, December 17, 2015 |
APPL NO | 14/973033 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/86 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926372 | Eriksson et al. |
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FUNDED BY |
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APPLICANT(S) | Ludwig Institute for Cancer Research Ltd (Zurich, Switzerland) |
ASSIGNEE(S) | Ludwig Institute for Cancer Research Ltd (Zurich, Switzerland); The Regents of the University of Michigan (Ann Arbor, Michigan); University of Maryland, Baltimore (Baltimore, Maryland) |
INVENTOR(S) | Ulf Eriksson (Stockholm, Sweden); Linda Fredriksson (Hagersten, Sweden); Daniel Lawrence (Ann Arbor, Michigan); Enming Su (Ann Arbor, Michigan); Manuel Yepes (Atlanta, Georgia); Dudley Strickland (Brookville, Maryland) |
ABSTRACT | Methods and compositions for modulating blood-neural barrier (BNB) for the treatment of CNS conditions such as edema, and for increased drug delivery efficacy across the BNB. The present invention further relates to improved tPA treatment of ischemic cerebrovascular and related diseases in combination with antagonism of the PDGF signaling pathway. The inventive method and composition is particularly suitable for conjunctive therapy of ischemic stroke using tPA and an anti-PDGF-C antagonist or an anti-PDGFR-α antagonist. |
FILED | Thursday, October 06, 2016 |
APPL NO | 15/286818 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/43 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/24 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6454 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926380 | Molldrem et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Jeffrey Molldrem (Houston, Texas); Anna Sergeeva (Houston, Texas) |
ABSTRACT | The specification describes the sequences for antibodies that recognize the HLA-A2-restricted peptide PR-1 in the context of HLA presentation on the surface of cancer cells. Use of these antibodies in the diagnosis and treatment of cancer and immune-related diseases are also provided. |
FILED | Wednesday, July 03, 2013 |
APPL NO | 14/413833 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 45/06 (20130101) A61K 47/6851 (20170801) A61K 47/6871 (20170801) Peptides C07K 16/30 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 16/2833 (20130101) C07K 16/3061 (20130101) C07K 2317/24 (20130101) C07K 2317/32 (20130101) C07K 2317/34 (20130101) C07K 2317/71 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/567 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57488 (20130101) G01N 2333/96433 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926381 | Welt et al. |
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FUNDED BY |
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APPLICANT(S) | Welt Bio-Molecular Pharmaceutlical, LLC (Armonk, New York) |
ASSIGNEE(S) | WELT BIO-MOLECULAR PHARMACEUTICAL, LLC. (Armonk, New York) |
INVENTOR(S) | Sydney Welt (Armonk, New York); David Kostyal (Akron, Ohio); Rachel S Welt (Armonk, New York); Virginia Raymond (Armonk, New York); Jonathan A Welt (Armonk, New York) |
ABSTRACT | The present invention relates to monoclonal antibodies targeting the membrane bound IgM (mIgM) of the B-cell receptor complex found in B-cell lymphomas and leukemias. Monoclonal antibodies designated mAb4-2b, mAb1-1, mAb2-2b and mAb3-2b were produced by hybridoma cell lines (ATCC deposit no. PTA-121716), (ATCC deposit no. PTA-121719), (ATCC deposit no. PTA-121717), and (ATCC deposit no. PTA-121718), respectively. Another aspect of the present invention is the use of anti-B-Cell mIgM antibodies in the treatment of B-cell malignancies, including B-cell lymphomas and leukemias. |
FILED | Monday, December 01, 2014 |
APPL NO | 15/101658 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 16/4283 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/34 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/77 (20130101) C07K 2317/565 (20130101) C07K 2317/732 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/163 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926535 | Kawaoka et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Taisuke Horimoto (Bankyotan, Japan); Shin Murakami (Mito, Japan) |
ABSTRACT | The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes at least five internal genes from an influenza virus isolate that replicates to high titers in embryonated chicken eggs or MDCK cells. |
FILED | Tuesday, January 19, 2016 |
APPL NO | 15/000851 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 2039/525 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/2402 (20130101) C12N 15/85 (20130101) C12N 2760/16051 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2800/107 (20130101) Enzymes C12Y 302/01018 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926545 | Joung et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Benjamin Kleinstiver (Medford, Massachusetts) |
ABSTRACT | Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities and their use in genomic engineering, epigenomic engineering, and genome targeting. |
FILED | Tuesday, July 12, 2016 |
APPL NO | 15/208228 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 2319/71 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/102 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 301/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926546 | Joung et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Benjamin Kleinstiver (Medford, Massachusetts); Vikram Pattanayak (Wellesley, Massachusetts) |
ABSTRACT | Engineered CRISPR-Cas9 nucleases with improved specificity and their use in genomic engineering, epigenomic engineering, genome targeting, and genome editing. |
FILED | Monday, August 29, 2016 |
APPL NO | 15/249756 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) Original (OR) Class C12N 15/902 (20130101) C12N 15/907 (20130101) Enzymes C12Y 301/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926552 | Craighead et al. |
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FUNDED BY |
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APPLICANT(S) | Harold G. Craighead (Ithaca, New York); Juraj Topolancik (San Jose, California); Harvey Tian (Fayetteville, Arkansas); Christopher Wallin (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Harold G. Craighead (Ithaca, New York); Juraj Topolancik (San Jose, California); Harvey Tian (Fayetteville, Arkansas); Christopher Wallin (Ithaca, New York) |
ABSTRACT | The present invention relates to a microfluidic device for extracting and isolating DNA from cells. The device includes a support having an inlet port for receiving a sample containing a cell, an outlet port for dispensing DNA isolated from the cell, and a microfluidic channel disposed within the support and extending from the inlet port to the outlet port. The microfluidic channel includes a micropillar array, an inflow channel disposed between the inlet port and the micropillar array, and an outflow channel disposed between the micropillar array and the outlet port. The micropillar array includes micropillars spatially configured to entrap, by size exclusion, the cell, to immobilize DNA released from the cell, and to maintain the immobilized DNA in elongated or non-elongated form when hydrodynamic force is applied to the microfluidic channel. Systems and methods of making and using the device are also provided herein. |
FILED | Wednesday, June 06, 2012 |
APPL NO | 14/124479 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0663 (20130101) B01L 2400/086 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926564 | Yarden et al. |
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FUNDED BY |
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APPLICANT(S) | Yeda Research and Development Co. Ltd. (Rehovot, Israel) |
ASSIGNEE(S) | Yeda Research and Development Co. Ltd. (Rehovot, Israel) |
INVENTOR(S) | Yosef Yarden (Rehovot, Israel); Michael Sela (Rehovot, Israel); Georg Mahlknecht (Rehovot, Israel); Ruth Maron (Rehovot, Israel); Bilha Schechter (Rehovot, Israel) |
ABSTRACT | Monomeric and multimeric aptamers are provided. Also provided are pharmaceutical compositions which comprise same and methods of using same. |
FILED | Sunday, October 27, 2013 |
APPL NO | 14/439248 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/16 (20130101) C12N 2310/51 (20130101) C12N 2310/51 (20130101) C12N 2310/351 (20130101) C12N 2310/3517 (20130101) C12N 2320/13 (20130101) C12N 2320/30 (20130101) C12N 2330/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/91205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926592 | Armitage et al. |
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FUNDED BY |
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APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania); UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania); UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Bruce A. Armitage (Pittsburgh, Pennsylvania); Patricia L. Opresko (Pittsburgh, Pennsylvania); Danith Ly (Pittsburgh, Pennsylvania); Nathaniel Shank (Pittsburgh, Pennsylvania) |
ABSTRACT | A category of γPNA miniprobes and chimeric γPNA probes is especially useful for detecting RNA and telomeric DNA in a cell sample. In particular, the probes can be used to deliver fluorescent dyes to the telomeres, allowing direct visualization of telomeres in cells. |
FILED | Wednesday, November 14, 2012 |
APPL NO | 14/357874 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/3181 (20130101) C12N 2320/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 2525/107 (20130101) C12Q 2565/101 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926596 | Esfandyarpour et al. |
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FUNDED BY |
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APPLICANT(S) | Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California) |
ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California) |
ABSTRACT | The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices. |
FILED | Tuesday, May 29, 2012 |
APPL NO | 14/119859 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2527/119 (20130101) C12Q 2527/119 (20130101) C12Q 2549/126 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926601 | Gertler et al. |
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FUNDED BY |
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APPLICANT(S) | Frank B. Gertler (Boston, Massachusetts); Christopher Boyce Burge (Belmont, Massachusetts); Irina M. Shapiro (Chestnut Hill, Massachusetts); Wu Albert Cheng (Somerville, Massachusetts); John S. Condeelis (Bronx, New York); Maja H. Oktay (Rye, New York) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Montefiore Medical Center (Bronx, New York); Albert Einstein College of Medicine, Inc. (Bronx, New York) |
INVENTOR(S) | Frank B. Gertler (Boston, Massachusetts); Christopher Boyce Burge (Belmont, Massachusetts); Irina M. Shapiro (Chestnut Hill, Massachusetts); Wu Albert Cheng (Somerville, Massachusetts); John S. Condeelis (Bronx, New York); Maja H. Oktay (Rye, New York) |
ABSTRACT | The present invention provides a method for identifying a tumor as likely to metastasize, or likely to have metastasized, comprising obtaining a sample of the tumor and quantitating alternatively spliced mRNA isoforms of a cell motility gene, a cell adhesion gene and/or an actin cytoskeletal remodeling gene in the sample, or any specified genes or the level of RNA binding proteins compared to a predetermined non-metastasizing control. |
FILED | Friday, February 24, 2012 |
APPL NO | 14/000995 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926602 | Chinnaiyan et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Aann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Arul M. Chinnaiyan (Plymouth, Michigan); Xiaosong Wang (Ann Arbor, Michigan) |
ABSTRACT | The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent gene fusions as diagnostic markers and clinical targets for prostate cancer. |
FILED | Wednesday, June 11, 2014 |
APPL NO | 14/302199 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/7028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926605 | Grandis et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Jennifer R. Grandis (Pittsburgh, Pennsylvania); Vivian Wai Yan Lui (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to HPV-positive as well as HPV-negative screening platforms that are highly serum-dependent, for use as HNSCC models. These HNSCC models die reproducibly in serum-deprived conditions and the introduction of driver mutations (or increased levels of the WT gene) confers enhanced cell survival and proliferation under serum deprivation. These platforms have the major advantages of allowing functional screening of mutations in relevant HNSCC models (HPV-positive and HPV-negative). In addition to oncogene screening, this model can also be used in drug discovery. Specifically, cells expressing mutations that confer increased survival can then be screened against panels of therapeutic agents to determine if the mutation(s) can predict the optimal treatment for patients whose tumors harbor the mutation(s). |
FILED | Friday, January 23, 2015 |
APPL NO | 14/604310 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926606 | Bardelli et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Alberto Bardelli (Turin, Italy); D. Williams Parsons (Bellaire, Texas); Victor Velculescu (Dayton, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland) |
ABSTRACT | Protein kinases are important signaling molecules involved in tumorigenesis. Mutational analysis of the human tyrosine kinase gene family (98 genes) identified somatic alterations in ˜20% of colorectal cancers, with the majority of mutations occurring in NTRK3, FES, GUCY2F and a previously uncharacterized tyrosine kinase gene called MCCK/MLK4. Most alterations were in conserved residues affecting key regions of the kinase domain. These data represent a paradigm for the unbiased analysis of signal transducing genes in cancer and provide useful targets for therapeutic intervention. |
FILED | Monday, December 07, 2015 |
APPL NO | 14/960681 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/485 (20130101) C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926612 | Woods et al. |
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FUNDED BY |
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APPLICANT(S) | Robert J. Woods (Athens, Georgia); Loretta Yang (San Diego, California) |
ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); Glycosensors and Diagnostics, LLC (Athens, Georgia) |
INVENTOR(S) | Robert J. Woods (Athens, Georgia); Loretta Yang (San Diego, California) |
ABSTRACT | Provided are lectenz molecules, which are mutated carbohydrate processing enzymes that are catalytically inactive and that have had their substrate affinity increased by at least 1.2 fold. Further provided are methods for making and methods of using such lectenz. Additional mutated proteins following the lectenz approach are further provided. |
FILED | Thursday, December 10, 2009 |
APPL NO | 13/148289 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/80 (20130101) C12N 9/82 (20130101) C12N 9/2402 (20130101) C12N 15/1089 (20130101) Enzymes C12Y 302/01018 (20130101) Original (OR) Class C12Y 302/01022 (20130101) C12Y 302/01023 (20130101) C12Y 302/01113 (20130101) C12Y 302/01169 (20130101) C12Y 305/01026 (20130101) C12Y 305/01052 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927178 | Srinivas et al. |
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FUNDED BY |
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APPLICANT(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
INVENTOR(S) | Girish Srinivas (Broomfield, Colorado); Steven Charles Gebhard (Golden, Colorado); Robert James Copeland (Metairie, Louisiana); David P. Eisenberg (Denver, Colorado) |
ABSTRACT | A seasonal process that captures stores and uses water in an ambient temperature-dependent manner to improve the efficiency of a natural gas power plant, comprising: (a) providing a natural gas power plant, the natural gas power plant having a flue gas stream, a cooling tower, and a gas turbine; (b) providing a water collection system; (c) providing a water storage facility; wherein the flue gas stream comprises uncondensed water vapor; wherein the water collection system is operably connected to the flue gas stream and the flue gas stream is directed to flow, at least in part, into the water collection system; wherein the water collection system is operably connected to the water storage facility; wherein the water storage facility is operably connected to the cooling tower and the water storage facility is operably connected to the gas turbine; wherein the process comprises the following steps of condensing flue gas water or using water that has been condensed from the flue gas stream based on outdoor ambient dry bulb temperature: (I) Only condensing water from the flue gas stream to produce a condensed water stream if outdoor ambient dry bulb temperature is less than 85° F.; (II) Only using condensed water to spray cool the cooling tower if outdoor ambient dry bulb temperature is at least 85° F.; (III) Only using condensed water to fog cool the gas turbine if outdoor ambient dry bulb temperature is at least 55° F.; wherein condensed water that is not immediately used to cool the cooling tower or to fog cool the gas turbine is stored in the water storage facility; and wherein the process uses a total amount of water on an annual basis to cool the cooling tower and to fog cool the gas turbine that does not exceed the annual amount of water condensed from the flue gas stream. Optionally, the process has a cooling tower that is a dry cooling tower and condensed water is used to spray cool the dry cooling tower, or the cooling tower is a wet cooling tower, or the cooling tower is a hybrid wet-dry cooling tower. The process may further comprise a water collection system having a three stage desiccant cycle and a calcium chloride desiccant that recovers at least about 60 wt % of the water from the flue gas, operates at or above ambient pressure or comprises plastic piping or plastic vessels. Or the process may further comprise using a water collection system having at least one direct contact condensing column that recovers at least about 60 wt % of the water from the flue gas, operates at or above ambient pressure or comprises plastic piping or plastic vessels. Or the process may further comprise using a water collection system having at least one direct contact condenser and a rotating wheel heat exchanger that recovers at least about 60 wt % of the water from the flue gas, operates at or above ambient pressure, or further comprises plastic piping or plastic vessels. The coefficient of performance for the cooling process is optionally at least 2.0. |
FILED | Sunday, May 08, 2016 |
APPL NO | 15/149152 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 9/003 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/31 (20130101) F05D 2220/32 (20130101) F05D 2260/213 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction F28C 1/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927334 | Murthy et al. |
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FUNDED BY |
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APPLICANT(S) | Shashi K. Murthy (Newton, Massachusetts); Adam Hatch (Cambridge, Massachusetts); George Hansmann (Boston, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Shashi K. Murthy (Newton, Massachusetts); Adam Hatch (Cambridge, Massachusetts); George Hansmann (Boston, Massachusetts) |
ABSTRACT | Disclosed herein are hydrogel compositions and methods of making hydrogel compositions. Furthermore, methods of specifically capturing and releasing biological materials from a sample using the disclosed hydrogel compositions are disclosed, including methods of utilizing the compositions in microfluidic devices. |
FILED | Friday, February 03, 2012 |
APPL NO | 13/982680 |
ART UNIT | 1677 — Printing/Measuring and Testing |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/061 (20130101) B01F 13/0059 (20130101) B01F 2005/0623 (20130101) B01F 2005/0636 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/069 (20130101) B01L 2300/0867 (20130101) B01L 2400/0478 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class G01N 33/548 (20130101) G01N 33/54386 (20130101) G01N 33/56966 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927336 | Meisberger et al. |
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FUNDED BY |
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APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Stephen P. Meisberger (Ithaca, New York); Matthew A. Warkentin (Ithaca, New York); Jesse B. Hopkins (Ithaca, New York); Andrea M. Katz (Ithaca, New York); Lois Pollack (Ithaca, New York); Robert E. Thorne (Ithaca, New York) |
ABSTRACT | Apparatus and methods for performing small angle X-ray scattering (SAXS) at low (cryogenic) temperatures for determining the structure of and changes in the structure of proteins, DNA, RNA, and other biological molecules and biomolecular assemblies and structures. A cryogenic, small angle X-ray scattering (SAXS) application sample holder, includes a sample cell including a base portion and at least two parallel walls disposed on the base, wherein the sample cell has a liquid volume capacity defined by the walls and the base portion of 0.001 to 10 microliters. A method for performing cryogenic SAXS on a sample includes the steps of providing a sample biomolecule solution containing an aqueous buffer, a biomolecule, and a cryoprotectant agent, wherein the cryoprotectant agent comprises up to 60% (w/w) of the biomolecule solution, and other known components as necessary to solubilize and stabilize the biomolecule, in a sample holder of claim 1, cryogenically cooling the sample solution in the sample holder at a rate equal to or greater than 100 K/sec without ice formation, and examining the cooled sample using small angle X-ray scattering by passing a beam of X-rays through the sample. |
FILED | Tuesday, June 04, 2013 |
APPL NO | 14/405253 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 23/201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927362 | Kumar et al. |
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FUNDED BY |
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APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Anand T. Kumar (Arlington, Massachusetts); Steven S. Hou (Malden, Massachusetts) |
ABSTRACT | System and method for optical tomographic imaging optimizing analysis of time-domain data as a result of combination of lifetime multiplexing of low-cross-talk asymptotic photons with highly spatially resolved early photons. The tomographic data reconstruction employs a decay amplitude-based asymptotic approach and a matrix equation with a weight matrix that includes two different portions respectively representing time domain sensitivity functions and continuous-tomography weight matrices. System may employ a lifetime fluorescent tomography imaging system. |
FILED | Friday, February 13, 2015 |
APPL NO | 15/118529 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) Original (OR) Class G01N 2201/06113 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927437 | Quintana et al. |
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FUNDED BY |
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APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Francisco J. Quintana (Jamaica Plain, Massachusetts); Lior Mayo (Fivataim, Israel); Howard Weiner (Brookline, Massachusetts); Reza Halse (Boston, Massachusetts) |
ABSTRACT | As described herein, lactosylceramide (LacCer) levels are up-regulated in the CNS during chronic experimental autoimmune encephalomyelitis (EAE), an experimental model of multiple sclerosis (MS). LacCer acts in an autocrine manner to trigger transcriptional programs that promote the recruitment and activation of CNS infiltrating monocytes and microglia, and neurodegeneration. In addition, increased B4GALT6 expression and LacCer levels were detected in CNS MS lesions in human patients. Finally, the inhibition of LacCer synthesis suppressed local CNS innate immunity and neurodegeneration in EAE, and interfered with the activation of human astrocytes in vitro. Thus, B4GALT6 is a therapeutic target for MS and other neuroinflammatory disorders. |
FILED | Friday, December 12, 2014 |
APPL NO | 15/103632 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/445 (20130101) A61K 31/713 (20130101) A61K 31/5375 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) Original (OR) Class G01N 2400/00 (20130101) G01N 2405/00 (20130101) G01N 2800/50 (20130101) G01N 2800/285 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927440 | Hellinga et al. |
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APPLICANT(S) | Homme W. Hellinga (Durham, North Carolina); Malin J. Allert (Raleigh, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Homme W. Hellinga (Durham, North Carolina); Malin J. Allert (Raleigh, North Carolina) |
ABSTRACT | Methods of optimizing mRNA sequences for expression in host cells are provided. Methods of determining the stability of a protein are also provided. Methods of determining the affinity of a ligand for a protein are also provided. |
FILED | Wednesday, November 24, 2010 |
APPL NO | 12/954317 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6803 (20130101) Original (OR) Class Electric Digital Data Processing G06F 19/16 (20130101) G06F 19/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927940 | Miller et al. |
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FUNDED BY |
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APPLICANT(S) | Earl Keith Miller (Cambridge, Massachusetts); Timothy Joseph Buschman (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Earl Keith Miller (Cambridge, Massachusetts); Timothy Joseph Buschman (Cambridge, Massachusetts) |
ABSTRACT | A method of displaying information includes presenting representations of information in a manner accounting for independent cognitive capacities corresponding to a subject's left and right halves of visual space. Weightings of importance may be assigned to the information and used to display the representations in the left half or the right half of the visual space with zero or few other representations. Presenting the representations can also include inspecting content of the information and determining a position on a display to present the content as a function of the information previously, currently, or in the future displayed on the display. In a display system, a presentation unit is configured to present, e.g. generate, representations of information in a manner accounting for the independent cognitive capacities, and a display unit is configured to display the representations. Displaying information can include arranging physical objects in locations of a subject's expected visual space. |
FILED | Friday, June 01, 2012 |
APPL NO | 13/486762 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Electric Digital Data Processing G06F 3/048 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928338 | Tang et al. |
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FUNDED BY |
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APPLICANT(S) | Hua Tang (Stanford, California); Michael Snyder (Stanford, California); Jennifer Li-Pook Than (Menlo Park, California); Konrad J. Karczewski (Stanford, California); Nicholas Johnson (Palo Alto, California); Wing H. Wong (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Hua Tang (Stanford, California); Michael Snyder (Stanford, California); Jennifer Li-Pook Than (Menlo Park, California); Konrad J. Karczewski (Stanford, California); Nicholas Johnson (Palo Alto, California); Wing H. Wong (Stanford, California) |
ABSTRACT | The present disclosure presents a unified system to phase a personal genome for downstream clinical interpretation. In an embodiment, an initial phasing is generated using public datasets, such as haplotypes from the 1000 Genomes Project, and a phasing toolkit. A local perturbation algorithm is applied to improve long range phasing. If available, a Mendelian inheritance pipeline is applied to identify phasing of novel and rare variants. These datasets are merged, followed by correction by any experimental data. This allows for full clinical interpretation of the role of a group of variants in a gene, whether inherited or de novo variants. |
FILED | Friday, June 01, 2012 |
APPL NO | 13/487064 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/22 (20130101) Original (OR) Class G06F 19/24 (20130101) G06F 19/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928344 | Rothenberg et al. |
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FUNDED BY |
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APPLICANT(S) | Marc E. Rothenberg (Cincinnati, Ohio); Ting Wen (Cincinnati, Ohio) |
ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
INVENTOR(S) | Marc E. Rothenberg (Cincinnati, Ohio); Ting Wen (Cincinnati, Ohio) |
ABSTRACT | Embodiments of the invention are directed to methods of diagnosing eosinophilic esophagitis (EoE), or remission therefrom in a subject, wherein the methods include applying a sample from the subject to a diagnostic panel that contains selected markers for EoE, analyzing to obtain relatedness information relative to an EoE cohort and making a determination as to the EoE status of the subject, wherein an analysis indicating grouping with an EoE cohort or a quantitative score similar to that of an EoE cohort are indicative of EoE in the subject. Embodiments of the invention are also directed to methods of monitoring the pathological development or medical prognosis of EoE in a subject. |
FILED | Thursday, June 21, 2012 |
APPL NO | 14/128322 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/49 (20130101) G01N 33/493 (20130101) G01N 33/6893 (20130101) G01N 2800/06 (20130101) G01N 2800/14 (20130101) G01N 2800/24 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) Electric Digital Data Processing G06F 19/20 (20130101) G06F 19/3431 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928617 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Quanzheng Li (Cambridge, Massachusetts); Georges El Fakhri (Brookline, Massachusetts) |
ABSTRACT | A system and method for determining, from registered positron emission tomography (PET) sinogram data and magnetic resonance (MR) image data, an estimated attenuation sinogram uses a data consistency condition to evaluate a gradient of the PET sinogram data using the MR image data. An image of the subject is reconstructed using the estimate attenuation sinogram. |
FILED | Thursday, March 14, 2013 |
APPL NO | 14/440981 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measurement of Nuclear or X-radiation G01T 1/1603 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 09924883 | Cui et al. |
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FUNDED BY |
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APPLICANT(S) | Xinyan T. Cui (Wexford, Pennsylvania); Carl F. Lagenaur (Pittsburgh, Pennsylvania); Erdrin Azemi (Sunnyvale, California); Noah R. Snyder (Glenshaw, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Xinyan T. Cui (Wexford, Pennsylvania); Carl F. Lagenaur (Pittsburgh, Pennsylvania); Erdrin Azemi (Sunnyvale, California); Noah R. Snyder (Glenshaw, Pennsylvania) |
ABSTRACT | Disclosed herein are neural probes comprising an L1 polypeptide functional fragment thereof on the exterior surface of the probe, devices including such electrodes, and methods of their use. The disclosed embodiments are useful, for example, for in methods of recording and/or stimulating neural signals in a subject. |
FILED | Friday, June 27, 2014 |
APPL NO | 14/317271 |
ART UNIT | 3739 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/688 (20130101) A61B 5/04001 (20130101) Original (OR) Class A61B 5/6868 (20130101) A61B 2562/125 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0526 (20130101) A61N 1/0529 (20130101) A61N 1/0534 (20130101) A61N 1/0551 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09924986 | Petrzelka et al. |
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FUNDED BY |
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APPLICANT(S) | Charles River Engineering Solutions and Technologies, LLC (Chapel Hill, North Carolina) |
ASSIGNEE(S) | Charles River Engineering Solutions and Technologies, LLC (Chapel Hill, North Carolina) |
INVENTOR(S) | Joseph E. Petrzelka (Marina del Rey, California); Manas C. Menon (Boston, Massachusetts); Suresh K. Agarwal (Chapel Hill, North Carolina); Dimitris Chatzigeorgiou (Somerville, Massachusetts); Michelle E. Lustrino (Cambridge, Massachusetts); Clara J. Stefanov-Wagner (Cambridge, Massachusetts) |
ABSTRACT | Disclosed are embodiments of an articulating tool having a head that articulates and is capable of maintaining an angle for drilling or placing a fastener into a bone. The articulating tool includes a housing, an articulating head, a rotatable drive shaft, and a driver tip connected to the distal shaft portion. The articulating tool may be constructed and arranged to move between a first position and a second position, wherein in the first position and the second position the articulating head and the rotatable drive shaft are at different angles with respect to the longitudinal axis of the housing. |
FILED | Monday, October 28, 2013 |
APPL NO | 14/065259 |
ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/808 (20130101) Original (OR) Class A61B 17/1631 (20130101) A61B 17/8875 (20130101) A61B 2017/003 (20130101) A61B 2017/00318 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925202 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
INVENTOR(S) | Jane Yu (Cincinnati, Ohio); Chenggang Li (Maineville, Ohio) |
ABSTRACT | Embodiments disclosed herein provide compositions and methods for treating lymphangioleiomyomatosis (LAM) comprising inhibiting COX overexpression and prostaglandin over production by administering at least one COX inhibitor and/or prostaglandin biosynthetic pathway inhibitors. Lymphangioleiomyomatosis (LAM) is a rare lung disease. Some LAM occurances are associated with mutations in the tuberous sclerosis complex (TSC) locus. LAM occurs almost exclusively in women, usually of childbearing age. |
FILED | Tuesday, March 04, 2014 |
APPL NO | 14/771817 |
ART UNIT | 1673 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/18 (20130101) A61K 31/18 (20130101) A61K 31/42 (20130101) A61K 31/42 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/365 (20130101) A61K 31/365 (20130101) A61K 31/405 (20130101) A61K 31/405 (20130101) A61K 31/415 (20130101) A61K 31/415 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/616 (20130101) Original (OR) Class A61K 31/616 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925210 | McCarthy et al. |
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FUNDED BY |
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APPLICANT(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
ASSIGNEE(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
INVENTOR(S) | Simon McCarthy (Portland, Oregon); Barbara McGrath (Portland, Oregon); Sam Kuhn (Portland, Oregon); Jess Kimball (Portland, Oregon); Michael Stolten (New Orleans, Louisiana); Amanda Bennett (New Orleans, Louisiana) |
ABSTRACT | The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid. Chitosan materials can be mixed in solution with one or more of other hydrophilic polymers to create compositional heterogeneity and pharmaceutical agents to achieve controlled release of the agent(s) from the final forms at the site of application. |
FILED | Wednesday, February 04, 2015 |
APPL NO | 14/614316 |
ART UNIT | 1673 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/70 (20130101) A61K 9/1652 (20130101) A61K 9/1694 (20130101) A61K 31/722 (20130101) Original (OR) Class A61K 47/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925249 | Siegel et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
ASSIGNEE(S) | University of Washington Through Its Center For Commercialization (Seattle, Washington) |
INVENTOR(S) | Justin Siegel (Seattle, Washington); David Baker (Seattle, Washington); Sydney Rin Anna Gordon (Seattle, Washington); Ingrid Swanson Pultz (Seattle, Washington); Elizabeth Joy Stanley (Bothell, Washington); Sarah Jane Wolf (Camas, Washington) |
ABSTRACT | The invention provides compositions and methods for treating celiac sprue. |
FILED | Monday, June 26, 2017 |
APPL NO | 15/633065 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/48 (20130101) A61K 38/482 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/50 (20130101) C12N 9/52 (20130101) Enzymes C12Y 304/21 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925254 | Guerry et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Patricia Guerry (Silver Spring, Maryland); Mario Artur Monteiro (Guelph, Canada); Yuening Jiao (Etobicoke, Canada) |
ABSTRACT | The invention relates to immunogenic synthetic constructs capable of inducing an immune response against Campylobacter jejuni (C. jejuni) in a subject comprising one or more monosaccharides comprising one or more MeOPN moieties. Specifically, the invention relates to immunogenic synthetic constructs capable of inducing an immune response against Campylobacter jejuni (C. jejuni) in a subject comprising one or more MeOPN→6 Gal monosaccharides. The invention also relates to compositions comprising the immunogenic synthetic constructs and methods of inducing an immune response against C. jejuni in a subject comprising administering the immunogenic synthetic constructs, and/or compositions comprising the immunogenic synthetic construct, to the subject. |
FILED | Thursday, November 05, 2015 |
APPL NO | 14/933793 |
ART UNIT | 1673 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/105 (20130101) Original (OR) Class A61K 2039/6037 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 11/04 (20130101) C07H 13/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925301 | Kaplan et al. |
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FUNDED BY |
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APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Biman B. Mandal (Kolkata, India) |
ABSTRACT | Provided herein relates to methods for preparing micron range silk fibers (or silk microfibers) and compositions comprising a micron range silk fiber (or a silk microfiber). The micron range silk fibers (or silk microfibers) can be used in various applications ranging from fillers in cosmetics to reinforcement materials to design high strength composites, e.g., reinforced scaffolds. In some embodiments, the silk microfiber-reinforced scaffolds can be used for bone graft applications because of their high compressive strength. |
FILED | Friday, April 05, 2013 |
APPL NO | 14/390362 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/365 (20130101) A61L 27/3604 (20130101) Original (OR) Class A61L 27/3687 (20130101) A61L 27/3821 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/02 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/045 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/02 (20130101) Chemical Treatment of Natural Filamentary or Fibrous Material to Obtain Filaments or Fibres for Spinning; Carbonising Rags to Recover Animal Fibres D01C 3/00 (20130101) Finishing or Dressing of Filaments, Yarns, Threads, Cords, Ropes or the Like D02J 1/00 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/4266 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/36 (20130101) D06M 2101/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925310 | McGrath et al. |
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FUNDED BY |
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APPLICANT(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
ASSIGNEE(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
INVENTOR(S) | Barbara McGrath (Portland, Oregon); Simon McCarthy (Portland, Oregon); Sam Kuhn (Portland, Oregon); Alysha Wold (Portland, Oregon); Michael Stolten (Portland, Oregon); Amanda Bennett (Portland, Oregon) |
ABSTRACT | The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition. |
FILED | Tuesday, December 06, 2016 |
APPL NO | 15/371010 |
ART UNIT | 1673 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/58 (20130101) Original (OR) Class A61L 2400/04 (20130101) Polysaccharides; Derivatives Thereof C08B 37/003 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 89/06 (20130101) C08L 2201/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 2333/545 (20130101) G01N 2400/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925319 | Valiorgue et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Pierre Valiorgue (West Lafayette, Indiana); Justin A. Weibel (West Lafayette, Indiana); Suresh V. Garimella (West Lafayette, Indiana) |
ABSTRACT | Methods and apparatuses for detection of gas bubbles in a microchannel configured for a conductive fluid to flow therethrough. The methods and apparatuses utilize a plate and at least two aligned electrodes embedded within the plate. The plate is configured to be located over the microchannel such that the at least two aligned electrodes are located along a length of the microchannel in the flow direction. Impedance is measured between the electrodes, and the percentage of gas within the fluid flowing through the microchannel is measured based on the measured impedance between the electrodes. |
FILED | Wednesday, March 30, 2016 |
APPL NO | 15/085673 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/16 (20130101) Original (OR) Class A61M 1/3626 (20130101) A61M 2205/0244 (20130101) A61M 2205/702 (20130101) A61M 2205/3317 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925519 | Soliz et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (APG, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jennifer R Soliz (Baltimore, Maryland); Christopher J Karwacki (Churchville, Maryland) |
ABSTRACT | A method and composition of matter for detecting and decontaminating hazardous chemicals, the composition of matter including: a magnetic material for any of chemisorbing, molecularly dissociating, or decomposing a hazardous chemical, wherein the magnetic material changes its magnetic moment upon any of chemisorption, decomposition, and molecular dissociation of the hazardous chemical and the change in magnetic moment is used to detect the presence of the hazardous chemical, and wherein the hazardous chemical includes any of toxic industrial chemicals, chemical warfare agents, and chemical warfare agent related compounds. |
FILED | Wednesday, September 20, 2017 |
APPL NO | 15/710272 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/33 (20130101) A62D 2101/02 (20130101) Separation B01D 53/04 (20130101) B01D 2253/1124 (20130101) B01D 2257/70 (20130101) B01D 2257/204 (20130101) B01D 2257/302 (20130101) B01D 2257/304 (20130101) B01D 2257/306 (20130101) B01D 2257/2064 (20130101) B01D 2257/2066 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/28009 (20130101) Original (OR) Class Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/0054 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/42 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/33 (20130101) G01N 21/35 (20130101) G01N 21/65 (20130101) G01N 27/72 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925520 | Soliz et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jennifer R Soliz (Baltimore, Maryland); Christopher J Karwacki (Churchville, Maryland) |
ABSTRACT | A method and composition of matter for detecting and decontaminating hazardous chemicals, the composition of matter including: a magnetic material for any of chemisorbing, molecularly dissociating, or decomposing a hazardous chemical, wherein the magnetic material changes its magnetic moment upon any of chemisorption, decomposition, and molecular dissociation of the hazardous chemical and the change in magnetic moment is used to detect the presence of the hazardous chemical, and wherein the hazardous chemical includes any of toxic industrial chemicals, chemical warfare agents, and chemical warfare agent related compounds. |
FILED | Thursday, September 21, 2017 |
APPL NO | 15/711195 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/33 (20130101) A62D 2101/02 (20130101) Separation B01D 53/04 (20130101) B01D 2253/1124 (20130101) B01D 2257/70 (20130101) B01D 2257/204 (20130101) B01D 2257/302 (20130101) B01D 2257/304 (20130101) B01D 2257/306 (20130101) B01D 2257/2064 (20130101) B01D 2257/2066 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/28009 (20130101) Original (OR) Class Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/0054 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/42 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/33 (20130101) G01N 21/35 (20130101) G01N 21/65 (20130101) G01N 27/72 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926025 | Blankespoor et al. |
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FUNDED BY |
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APPLICANT(S) | Google Inc. (Mountain View, California) |
ASSIGNEE(S) | Boston Dynamics, Inc. (Mountain View, California) |
INVENTOR(S) | Kevin Blankespoor (Mountain View, California); Marco da Silva (Mountain View, California); Alex Perkins (Mountain View, California) |
ABSTRACT | An example method may include i) determining, by a robot having at least one foot, a representation of a coefficient of friction between the foot and a ground surface; ii) determining, by the robot, a representation of a gradient of the ground surface; iii) based on the determined representations of the coefficient of friction and the gradient, determining a threshold orientation for a target ground reaction force on the foot of the robot during a step; iv) determining the target ground reaction force, where the target ground reaction force comprises a magnitude and an orientation; v) determining an adjusted ground reaction force by adjusting the orientation of the target ground reaction force to be within the determined threshold orientation; and vi) causing the foot of the robot to apply a force on the ground surface equal to and opposing the adjusted ground reaction force during the step. |
FILED | Friday, April 21, 2017 |
APPL NO | 15/493790 |
ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/162 (20130101) B25J 9/1615 (20130101) Motor Vehicles; Trailers B62D 57/032 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) Y10S 901/46 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926496 | Tonkovich et al. |
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FUNDED BY |
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APPLICANT(S) | Velocys, Inc. (Plain City, Ohio) |
ASSIGNEE(S) | Velocys, Inc. (Plain City, Ohio) |
INVENTOR(S) | Anna Lee Tonkovich (Gilbert, Arizona); Ravi Arora (New Albany, Ohio); John Brophy (Bath, United Kingdom); Francis P. Daly (Delaware, Ohio); Soumitra Deshmukh (Dublin, Ohio); Maddalena Fanelli (Columbus, Ohio); Kai Tod Paul Jarosch (Bexley, Ohio); Timothy J. LaPlante (Powell, Ohio); Richard Q. Long (New Albany, Ohio); Terry Mazanec (Solon, Ohio); Daniel Francis Ryan (Brewster, Massachusetts); Laura J. Silva (Dublin, Ohio); Wayne W. Simmons (Dublin, Ohio); Bruce Strangeland (Berkeley, Ohio); Yong Wang (Richland, Washington); Thomas Yuschak (Lewis Center, Ohio); Steven T. Perry (Galloway, Ohio); Jeffrey Dale Marco (South Charleston, Ohio); Michael Alan Marchiando (London, Ohio); Robert Lewis Litt (Westerville, Ohio) |
ABSTRACT | This invention relates to a process for conducting a hydrocracking or a hydrotreating process in a microchannel reactor. This invention also relates to a process and apparatus for flowing a vapor and liquid into a plurality of microchannels in a microchannel processing unit. |
FILED | Wednesday, May 28, 2014 |
APPL NO | 14/288936 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 21/12 (20130101) B01J 23/42 (20130101) B01J 23/75 (20130101) B01J 23/96 (20130101) B01J 35/023 (20130101) B01J 2219/00783 (20130101) B01J 2219/00788 (20130101) B01J 2219/00835 (20130101) B01J 2219/00873 (20130101) B01J 2219/00889 (20130101) B01J 2219/00891 (20130101) B01J 2219/00984 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/32 (20130101) C10G 45/02 (20130101) C10G 47/00 (20130101) C10G 47/02 (20130101) C10G 47/14 (20130101) Original (OR) Class C10G 2300/202 (20130101) C10G 2300/4018 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/582 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926505 | Harvey |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Benjamin G. Harvey (China Lake, California) |
ABSTRACT | A method to generate dense, multi-cyclic diamondoid fuels from bio-derived sesquiterpenes. This process can be conducted with both heterogeneous and homogenous catalysts and produces the targeted isomers in high yield. The resulting multi-cyclic structures impart significantly higher densities and volumetric net heats of combustion while maintaining low viscosities which allow for use at low temperature/high altitude. Moreover, bio-derived sesquiterpenes can be produced from renewable biomass sources. Use of these fuels will decrease Navy dependence on fossil fuels and will also reduce net carbon emissions. |
FILED | Thursday, August 03, 2017 |
APPL NO | 15/667942 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 5/03 (20130101) C07C 5/31 (20130101) C07C 45/68 (20130101) C07C 2603/74 (20170501) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/1608 (20130101) Original (OR) Class C10L 1/1857 (20130101) C10L 10/12 (20130101) C10L 2200/0469 (20130101) C10L 2290/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926534 | Adams et al. |
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FUNDED BY |
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APPLICANT(S) | André A. Adams (Burke, Virginia); Michael Daniele (Arlington, Virginia); Frances S. Ligler (Fuquay Varina, North Carolina) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | André A. Adams (Burke, Virginia); Michael Daniele (Arlington, Virginia); Frances S. Ligler (Fuquay Varina, North Carolina) |
ABSTRACT | A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves. |
FILED | Wednesday, July 01, 2015 |
APPL NO | 14/789440 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2240/001 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 2219/0086 (20130101) B01J 2219/0093 (20130101) B01J 2219/00783 (20130101) B01J 2219/00831 (20130101) B01J 2219/00833 (20130101) B01J 2219/00873 (20130101) B01J 2219/00889 (20130101) B01J 2219/00891 (20130101) B01J 2219/00936 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502746 (20130101) B01L 3/502776 (20130101) B01L 2200/10 (20130101) B01L 2200/12 (20130101) B01L 2200/0636 (20130101) B01L 2300/12 (20130101) B01L 2300/16 (20130101) B01L 2300/0838 (20130101) B01L 2300/0887 (20130101) B01L 2400/084 (20130101) B01L 2400/0487 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/0078 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/006 (20130101) B29K 2995/0056 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2009/00 (20130101) B29L 2023/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 25/10 (20130101) C12M 25/12 (20130101) C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) C12N 5/0697 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/032 (20130101) G02B 2006/0325 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926649 | Keller et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represent by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Teddy M. Keller (Fairfax Station, Virginia); Matthew Laskoski (Springfield, Virginia) |
ABSTRACT | Disclosed is a method of: providing a mixture of a polymer or a resin and a transition metal compound, producing a fiber from the mixture, and heating the fiber under conditions effective to form a carbon nanotube-containing carbonaceous fiber. The polymer or resin is an aromatic polymer or a precursor thereof and the mixture is a neat mixture or is combined with a solvent. Also disclosed are a carbonaceous fiber or carbonaceous nanofiber sheet having at least 15 wt. % carbon nanotubes, a fiber or nanofiber sheet having the a polymer or a resin and the transition metal compound, and a fiber or nanofiber sheet having an aromatic polymer and metal nanoparticles. |
FILED | Tuesday, January 19, 2016 |
APPL NO | 15/000406 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/16 (20170801) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/02 (20130101) D01F 9/12 (20130101) Original (OR) Class D01F 9/14 (20130101) D01F 9/127 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/4242 (20130101) Technical Subjects Covered by Former US Classification Y10T 442/60 (20150401) Y10T 442/658 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926789 | Hagan et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
INVENTOR(S) | Benjamin F. Hagan (Manchester, Connecticut); Ryan Alan Waite (Glastonbury, Connecticut); Dominic J. Mongillo (West Hartford, Connecticut) |
ABSTRACT | A flow splitting baffle for separating a main cooling flow through an inner channel of a component includes a tubular structure defining a tubular cavity and having a longitudinal axis. The flow splitting baffle also includes an inner ring coupled to the tubular structure and extending away from the tubular structure along a plane that is perpendicular to the longitudinal axis. The flow splitting baffle also includes an outer ring parallel to the plane, positioned a first distance from the tubular structure, extending away from the tubular structure and positioned a second distance from the inner ring. The flow splitting baffle also includes a strut perpendicular to the plane, extending from the inner ring to the outer ring and coupled to the inner ring and the outer ring. |
FILED | Friday, May 08, 2015 |
APPL NO | 14/707928 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 5/147 (20130101) F01D 5/189 (20130101) Original (OR) Class F01D 9/065 (20130101) F01D 25/005 (20130101) F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/50 (20130101) F05D 2230/60 (20130101) F05D 2260/20 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926799 | Romanov et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
INVENTOR(S) | Dmitriy A. Romanov (Wells, Maine); Dominic J. Mongillo, Jr. (West Hartford, Connecticut); Paul M. Lutjen (Kennebunkport, Maine) |
ABSTRACT | A gas turbine engine component is provided. The gas turbine engine component has an internal cooling passage having first endwall and a second endwall. A primary inlet aperture is in fluid communication with a coolant supply and the first end of the internal cooling passage. An elongated rib is inside the internal cooling passage and proximate the primary inlet aperture. The elongated rib is configured to direct at least a portion of the coolant from the primary inlet aperture against a proximate one of the first or second endwall and then substantially reverse direction to flow downstream toward a second end of the internal cooling passage. A blade outer air seal (“BOAS”) assembly and a BOAS segment thereof are also provided. |
FILED | Monday, October 12, 2015 |
APPL NO | 14/881047 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) F01D 9/023 (20130101) F01D 11/08 (20130101) Original (OR) Class F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/22141 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927038 | Adamo et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Andrea Adamo (Cambridge, Massachusetts); Alexander P. Clayton (Mascoutac, Illinois); Patrick Louis Heider (Midland, Michigan); Nopphon Weeranoppanant (Cambridge, Massachusetts); Klavs F. Jensen (Lexington, Massachusetts) |
ABSTRACT | Pressure control in fluidic systems is generally described. In some cases, a system comprises a fluid-permeable (e.g., liquid-permeable) medium and a pressure regulator. The medium and the pressure regulator can be positioned between a first fluidic channel and a second fluidic channel. The medium is arranged, in certain cases, such that fluid (e.g., liquid) can be transported from the first fluidic channel, through the medium, and into the second fluidic channel. In certain cases, when a first pressure within the first fluidic channel is below a sum of the permeability pressure differential of the medium with respect to the fluid and a second pressure within the second fluidic channel, the fluid is substantially prevented from being transported through an outlet of the first fluidic channel. |
FILED | Friday, August 09, 2013 |
APPL NO | 14/420683 |
ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502723 (20130101) B01L 3/502738 (20130101) B01L 2200/0673 (20130101) B01L 2200/0684 (20130101) B01L 2300/0681 (20130101) B01L 2300/0864 (20130101) B01L 2300/0874 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 15/14 (20130101) Original (OR) Class F16K 99/0015 (20130101) F16K 99/0057 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/7793 (20150401) Y10T 137/87249 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927060 | Moses et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Matthew S. Moses (Lafayette, Colorado); Christopher Y. Brown (Olney, Maryland); Charbel G. Rizk (Sykesville, Maryland); Jason E. Tiffany (Columbia, Maryland); Michael D. Kutzer (Baltimore, Maryland); David H. Scheidt (Edgewater, Maryland) |
ABSTRACT | A vehicle includes a head section having a selectively actuated first plurality of claws, a tail section having a selectively actuated second plurality of claws, and a linear actuator operably coupling the head section to the tail section. The linear actuator is configured to be selectively extended and retracted. The vehicle is configured to move forward within an enclosed space by extending the linear actuator, while the first plurality of claws is not actuated and the second plurality of claws is actuated, then retracting the linear actuator, while the first plurality of claws is actuated and the second plurality of claws is not actuated. |
FILED | Wednesday, April 20, 2016 |
APPL NO | 15/133251 |
ART UNIT | 3611 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/041 (20130101) A61B 1/00108 (20130101) A61B 1/00156 (20130101) A61B 2034/302 (20160201) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 55/34 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927123 | Hagan |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Benjamin F. Hagan (Manchester, Connecticut) |
ABSTRACT | A fluid transport system for a gas turbine engine includes a plenum configured to provide a fluid, an airfoil having an internal cavity, and a transfer tube arranged to transfer the fluid between the plenum and the internal cavity of the airfoil. The transfer tube includes an inlet, an outlet, a cavity extending from the inlet to the outlet, and at least one partition wall dividing the cavity into multiple flow passages. |
FILED | Monday, October 20, 2014 |
APPL NO | 14/517962 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/065 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/26 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927217 | Carlson et al. |
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FUNDED BY |
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APPLICANT(S) | Valley Tech Systems (Reno, Nevada) |
ASSIGNEE(S) | Valley Tech Systems, Inc. (Reno, Nevada) |
INVENTOR(S) | Russell Carlson (Reno, Nevada); Dustin Barr (Reno, Nevada); Allen Yan (Reno, Nevada) |
ABSTRACT | An attitude control system for a guided missile includes a gas generator, an accumulator coupled to the gas generator, and a valve positioned between the gas generator and the accumulator. The gas generator contains propellant that burns to provide hot gas to pressurize the accumulator. The valve is opened to recharge the accumulator with hot gas and closed when it is full. A vent valve can be included to extinguish the propellant in the gas generator. The accumulator can be coupled to thrusters that use the stored hot gas to adjust the attitude of the guided missile. |
FILED | Tuesday, September 08, 2015 |
APPL NO | 14/847820 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/661 (20130101) Original (OR) Class F42B 15/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927363 | Lin et al. |
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FUNDED BY |
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APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Tempe, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Tempe, Arizona) |
INVENTOR(S) | Zhi-Yuan Lin (Tempe, Arizona); Yong-Hang Zhang (Tempe, Arizona) |
ABSTRACT | Systems and methods for a real-time baseline correction technique for infrared time-resolved photoluminescence are disclosed. |
FILED | Thursday, March 24, 2016 |
APPL NO | 15/080447 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/274 (20130101) G01N 21/6408 (20130101) G01N 21/6489 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927381 | Schindelholz et al. |
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FUNDED BY |
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APPLICANT(S) | LUNA INNOVATIONS INCORPORATED (Roanoke, Virginia) |
ASSIGNEE(S) | Luna Innovations Incorporated (Roanoke, Virginia) |
INVENTOR(S) | Mara Elizabeth Schindelholz (Roanoke, Virginia); Fritz John Friedersdorf (Roanoke, Virginia); Nathan Kelly Brown (Roanoke, Virginia); Jeffrey Coleman Demo (Roanoke, Virginia); Conrad Koeing Andrews (Roanoke, Virginia); Paul Gordon Muskopf (Roanoke, Virginia) |
ABSTRACT | A sensing device includes a pair of contactless electrodes for placement on a coating on a surface of a structure or within or between one or more coatings on or over the surface of the structure. The electrodes function as sensors when activated to generate a current flow through the electrodes at multiple different frequencies. The sensing device also includes contactless control circuitry co-located with or separate from the electrodes that transmits impedance data generated from the activated electrodes. The impedance data is associated with corrosion condition information of the structure and/or the one or more coatings. A data collection system and display system useable with the sensing device are also described. |
FILED | Monday, June 22, 2015 |
APPL NO | 14/746144 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/026 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927397 | Brueck et al. |
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FUNDED BY |
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APPLICANT(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Jeremy Scott Edwards (Albuquerque, New Mexico); Alexander Neumann (Albuquerque, New Mexico); Yuliya Kuznetsova (Albuquerque, New Mexico); Edgar A. Mendoza (Redondo Beach, California); C. Jeffrey Brinker (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Jeremy Scott Edwards (Albuquerque, New Mexico); Alexander Neumann (Albuquerque, New Mexico); Yuliya Kuznetsova (Albuquerque, New Mexico); Edgar A. Mendoza (Redondo Beach, California); C. Jeffrey Brinker (Albuquerque, New Mexico) |
ABSTRACT | Methods and apparatus for long read, label-free, optical nanopore long chain molecule sequencing. In general, the present disclosure describes a novel sequencing technology based on the integration of nanochannels to deliver single long-chain molecules with widely spaced (>wavelength), ˜1-nm aperture “tortuous” nanopores that slow translocation sufficiently to provide massively parallel, single base resolution using optical techniques. A novel, directed self-assembly nanofabrication scheme using simple colloidal nanoparticles is used to form the nanopore arrays atop nanochannels that unfold the long chain molecules. At the surface of the nanoparticle array, strongly localized electromagnetic fields in engineered plasmonic/polaritonic structures allow for single base resolution using optical techniques. |
FILED | Wednesday, November 26, 2014 |
APPL NO | 14/555453 |
ART UNIT | 1757 — Printing/Measuring and Testing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 2200/0663 (20130101) B01L 2400/0421 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927457 | Nootz et al. |
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FUNDED BY |
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APPLICANT(S) | Gero A Nootz (Monterey, California); Fraser Dalgleish (Vero Beach, Florida); William T Rhodes (Boca Raton, Florida); Weilin Hou (Slidell, Louisiana) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Gero A Nootz (Monterey, California); Fraser Dalgleish (Vero Beach, Florida); William T Rhodes (Boca Raton, Florida); Weilin Hou (Slidell, Louisiana) |
ABSTRACT | System and method for remotely sensing the cross-flow orientation of a fluid (including a gaseous fluid) over an extended range. A Fourier transform of beam wander of a single beam can be used to determine the orientation of the flow field. Many applications depend upon accurate flow orientation data to provide correct information such as, for example, citing of turbines on wind farms and atmospheric/ocean weather prediction. |
FILED | Friday, August 22, 2014 |
APPL NO | 14/466131 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 13/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927458 | Bramhavar et al. |
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FUNDED BY |
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APPLICANT(S) | Suraj Deepak Bramhavar (Cambridge, Massachusetts); Paul William Juodawlkis (Arlington, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Suraj Deepak Bramhavar (Cambridge, Massachusetts); Paul William Juodawlkis (Arlington, Massachusetts) |
ABSTRACT | The accelerometers disclosed herein provide excellent sensitivity, long-term stability, and low SWaP-C through a combination of photonic integrated circuit technology with standard micro-electromechanical systems (MEMS) technology. Examples of these accelerometers use optical transduction to improve the scale factor of traditional MEMS resonant accelerometers by accurately measuring the resonant frequencies of very small (e.g., about 1 μm) tethers attached to a large (e.g., about 1 mm) proof mass. Some examples use ring resonators to measure the tether frequencies and some other examples use linear resonators to measure the tether frequencies. Potential commercial applications span a wide range from seismic measurement systems to automotive stability controls to inertial guidance to any other application where chip-scale accelerometers are currently deployed. |
FILED | Friday, May 27, 2016 |
APPL NO | 15/166599 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/093 (20130101) G01P 15/097 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927482 | Halter |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Mark Halter (Washington, Indiana) |
ABSTRACT | Various electrostatic protection testing, monitoring, and human-machine visual interface systems and methods are provided. Embodiments include systems and methods for implementing an automated grounding wrist strap assembly test system and visual interface. Embodiments include a test station interface section, a computer system coupled with the test station interface section, software operable to control the test station and computer system, and a user interface that tracks dates of testing a ground strap or system and generates color coding associated with various status of testing of each tracked strap. Additional embodiments include access control systems that allow or deny access to entryways, access points, equipment stations as well as disabling operation of equipment. Embodiments also include a variety of warning systems that trigger based on pass or fail conditions. |
FILED | Friday, October 30, 2015 |
APPL NO | 14/928600 |
ART UNIT | 2862 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 27/025 (20130101) G01R 31/001 (20130101) G01R 31/021 (20130101) G01R 31/026 (20130101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927574 | Budd et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Russell A. Budd (North Salem, New York); Daniel M. Kuchta (Patterson, New York); Benjamin Giles Lee (New York, New York); Laurent Schares (Sleepy Hollow, New York); Clint Lee Schow (Ossining, New York) |
ABSTRACT | An optical component includes a component body, and at least one angled-facet waveguide formed in the component body, wherein the angled-facet waveguide is substantially mirror-symmetrical in shape relative to a line at or near the center of the angled-facet waveguide. |
FILED | Tuesday, January 31, 2017 |
APPL NO | 15/420668 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 6/136 (20130101) G02B 6/423 (20130101) G02B 6/3652 (20130101) G02B 6/4243 (20130101) G02B 2006/12119 (20130101) G02B 2006/12166 (20130101) G02B 2006/12173 (20130101) G02B 2006/12176 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927578 | Davis |
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FUNDED BY |
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APPLICANT(S) | Edward Davis (Kihei, Hawaii) |
ASSIGNEE(S) | Trex Enterprises Corp. (San Diego, California) |
INVENTOR(S) | Edward Davis (Kihei, Hawaii) |
ABSTRACT | A fiber optic rotary connector providing communication between a first fiber optical bundle and a second fiber optical bundle rotating relative to said first bundle. The fiber optic rotary connector includes a K-mirror comprised of at least three mirror components and a set of gears adapted to rotate said K-mirror at a rotation rate equal to one half of the second bundle rotation rate. In a preferred embodiment the set of gears is a set of magnetic gears. And in another preferred embodiment the set of gears is a set of mechanical gears. Normally the first fiber optic bundle is stationary, but it may be rotating at a slower rate than the second bundle. In preferred embodiments the K mirror is comprised of three flat mirrors and two of the flat mirrors are positioned at about 30 degrees relative to the third flat mirror. |
FILED | Wednesday, September 14, 2011 |
APPL NO | 13/200031 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/32 (20130101) G02B 6/3604 (20130101) Original (OR) Class G02B 6/3664 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927616 | Hsu et al. |
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FUNDED BY |
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APPLICANT(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Chicago, Illinois); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Chicago, Illinois); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | Transparent displays enable many useful applications, including heads-up displays for cars and aircraft as well as displays on eyeglasses and glass windows. Unfortunately, transparent displays made of organic light-emitting diodes are typically expensive and opaque. Heads-up displays often require fixed light sources and have limited viewing angles. And transparent displays that use frequency conversion are typically energy inefficient. Conversely, the present transparent displays operate by scattering visible light from resonant nanoparticles with narrowband scattering cross sections and small absorption cross sections. More specifically, projecting an image onto a transparent screen doped with nanoparticles that selectively scatter light at the image wavelength(s) yields an image on the screen visible to an observer. Because the nanoparticles scatter light at only certain wavelengths, the screen is practically transparent under ambient light. Exemplary transparent scattering displays can be simple, inexpensive, scalable to large sizes, viewable over wide angular ranges, energy efficient, and transparent simultaneously. |
FILED | Tuesday, August 16, 2016 |
APPL NO | 15/237800 |
ART UNIT | 2875 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/0242 (20130101) G02B 5/0278 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/0112 (20130101) G02B 2027/0145 (20130101) G02B 2027/0147 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927706 | Nealey et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Paul Franklin Nealey (Chicago, Illinois); Tzu-Hsuan Chang (Madison, Wisconsin); Shisheng Xiong (Darien, Illinois); Zhenqiang Ma (Middleton, Wisconsin); Michael Scott Arnold (Middleton, Wisconsin); Robert Jacobberger (Madison, Wisconsin) |
ABSTRACT | Provided herein are methods of directed self-assembly (DSA) on atomic layer chemical patterns and related compositions. The atomic layer chemical patterns may be formed from two-dimensional materials such as graphene. The atomic layer chemical patterns provide high resolution, low defect directed self-assembly. For example, DSA on a graphene pattern can be used achieve ten times the resolution of DSA that is achievable on a three-dimensional pattern such as a polymer brush. Assembly of block copolymers on the atomic layer chemical patterns may also facilitate subsequent etch, as the atomic layer chemical patterns are easier to etch than conventional pattern materials. |
FILED | Wednesday, July 20, 2016 |
APPL NO | 15/215016 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 153/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/0227 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/002 (20130101) G03F 7/165 (20130101) Original (OR) Class G03F 7/168 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32009 (20130101) H01J 2237/334 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02527 (20130101) H01L 21/02568 (20130101) H01L 21/3081 (20130101) H01L 21/3086 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927806 | George |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jemin George (Silver Spring, Maryland) |
ABSTRACT | An apparatus and method for estimation of a system having state variables representing the state of the system comprising predicting the estimate of the state variables along with the uncertainties in the state variables; observing a measurement of at least one state variable corrupted with some amount of error; updating the estimates of the state variables using a weighted average, with more weight being given to estimates with higher certainty; and providing an estimator input to update the estimates of the state variables, the estimator input operating to provide asymptotic convergence of the mean estimation error in all of the state variables in the presence of persistent excitation or disturbance that is not asymptotically decaying to zero. |
FILED | Thursday, January 03, 2013 |
APPL NO | 13/733181 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0254 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928033 | Merrill |
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FUNDED BY |
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APPLICANT(S) | NVIDIA CORPORATION (Santa Clara, California) |
ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
INVENTOR(S) | Duane Merrill (Charlottesville, Virginia) |
ABSTRACT | One embodiment of the present invention performs a parallel prefix scan in a single pass that incorporates variable look-back. A parallel processing unit (PPU) subdivides a list of inputs into sequentially-ordered segments and assigns each segment to a streaming multiprocessor (SM) included in the PPU. Notably, the SMs may operate in parallel. Each SM executes write operations on a segment descriptor that includes the status, aggregate, and inclusive-prefix associated with the assigned segment. Further, each SM may execute read operations on segment descriptors associated with other segments. In operation, each SM may perform reduction operations to determine a segment-wide aggregate, may perform look-back operations across multiple preceding segments to determine an exclusive-prefix, and may perform a scan seeded with the exclusive prefix to generate output data. Advantageously, the PPU performs one read operation per input, thereby reducing the time required to execute the prefix scan relative to prior-art parallel implementations. |
FILED | Tuesday, October 01, 2013 |
APPL NO | 14/043626 |
ART UNIT | 2199 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 7/506 (20130101) Original (OR) Class G06F 8/456 (20130101) G06F 2207/5063 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928034 | Merrill, III |
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FUNDED BY |
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APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
INVENTOR(S) | Duane George Merrill, III (Charlotesville, Virginia) |
ABSTRACT | A method, computer readable medium, and system are disclosed for processing a segmented data set. The method includes the steps of receiving a data structure storing a plurality of values segmented into a plurality of sequences; assigning a plurality of processing elements to process the plurality of values; and processing the plurality of values by the plurality of processing elements according to a merge-based algorithm. Each processing element in the plurality of processing elements identifies a portion of values in the plurality of values allocated to the processing element based on the merge-based algorithm. In one embodiment, the processing elements are threads executed in parallel by a parallel processing unit. |
FILED | Wednesday, December 16, 2015 |
APPL NO | 14/971999 |
ART UNIT | 2196 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 7/523 (20130101) Original (OR) Class G06F 9/5066 (20130101) G06F 15/16 (20130101) G06F 2209/5018 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928214 | Avron et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Haim Avron (White Plains, New York); Vikas Sindhwani (Hawthorne, New York); David P. Woodruff (Mountain View, California) |
ABSTRACT | A system, method and computer program product for quickly and approximately solving structured regression problems. In one aspect, the system, method and computer program product are applied to problems that arise naturally in various statistical modeling settings—when the design matrix is a Vandermonde matrix or a sequence of such matrices. Using the Vandermonde matrix structure further accelerates the solution of the regression problem, achieving running times that are faster than “input sparsity”. The modeling framework speedup benefits of randomized regression for solving structured regression problems. |
FILED | Thursday, July 17, 2014 |
APPL NO | 14/333978 |
ART UNIT | 2853 — Printing/Measuring and Testing |
CURRENT CPC | Electric Digital Data Processing G06F 17/10 (20130101) G06F 17/16 (20130101) G06F 17/18 (20130101) Original (OR) Class G06F 17/2785 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928235 | Beller et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Edward G. Katz (Washington, District of Columbia); Alexander C. Tonetti (Washington, District of Columbia) |
ABSTRACT | A mechanism is provided in a data processing system having a processor and a memory storing a store of semantic types and instructions for implementing a natural language processing engine for generating semantically equivalent variants of a natural language term. The mechanism receives an input term for variant analysis. The natural language processing engine executing on the data processing system identifies a semantic type of the input term based on a store of semantic types. The natural language processing engine performs a type-specific series of rule-based expansions of the input term based on the identified semantic type of the input term to form a set of semantically equivalent variants of the input term. The natural language processing engine performs a natural language processing operation using the input term and the set of semantically equivalent variants of the input term. |
FILED | Thursday, July 07, 2016 |
APPL NO | 15/203946 |
ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
CURRENT CPC | Electric Digital Data Processing G06F 17/2785 (20130101) Original (OR) Class G06F 17/2795 (20130101) G06F 17/30654 (20130101) G06F 17/30684 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928278 | Welinder et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Peter Welinder (San Diego, California); Pietro Perona (Altadena, California) |
ABSTRACT | Systems and methods for distributed data annotation in accordance embodiments of the invention are disclosed. In one embodiment of the invention, a distributed data annotation server system includes a storage device configured to store source data, one or more annotators, annotation tasks and a processor, wherein a distributed data annotation application configures the processor to receive source data including one or more pieces of source data, select one or more annotators, create one or more annotation tasks for the selected annotators and source data, request one or more annotations for the source data using the annotation tasks, receive annotations, determine source data metadata for at least one piece of source data using the received annotations, generate annotator metadata for at least one annotator using the received annotations and the source data, and estimate the ground truth for the source data using the source data metadata and the annotator metadata. |
FILED | Thursday, March 06, 2014 |
APPL NO | 14/198873 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 17/301 (20130101) G06F 17/30011 (20130101) G06F 17/30525 (20130101) Original (OR) Class G06F 17/30864 (20130101) G06F 17/30867 (20130101) G06F 17/30997 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/101 (20130101) G06Q 50/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929243 | Corrion et al. |
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FUNDED BY |
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APPLICANT(S) | HRL LABORATORIES, LLC. (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Andrea Corrion (Oak Park, California); Keisuke Shinohara (Thousand Oaks, California); Miroslav Micovic (Thousand Oaks, California); Rongming Chu (Newbury Park, California); David F. Brown (Woodland Hills, California); Alexandros D. Margomenos (Pasadena, California); Shawn D. Burnham (Oxnard, California) |
ABSTRACT | A method of making a stepped field gate for an FET including forming a first passivation layer on a barrier layer, defining a first field plate by using electron beam (EB) lithography and by depositing a first negative EB resist, forming a second passivation layer over first negative EB resist and the first passivation layer, planarizing the first negative EB resist and the second passivation layer, defining a second field plate by using EB lithography and by depositing a second negative EB resist connected to the first negative EB resist, forming a third passivation layer over second negative EB resist and the second passivation layer, planarizing the second negative EB resist and the third passivation layer, removing the first and second negative EB resist, and forming a stepped field gate by using lithography and plating in a void left by the removed first and second negative EB resist. |
FILED | Monday, August 03, 2015 |
APPL NO | 14/816850 |
ART UNIT | 2813 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/78 (20130101) H01L 29/205 (20130101) H01L 29/407 (20130101) H01L 29/495 (20130101) H01L 29/2003 (20130101) H01L 29/42376 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929343 | Snaith et al. |
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FUNDED BY |
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APPLICANT(S) | ISIS INNOVATION LIMITED (Oxfordshire, United Kingdom) |
ASSIGNEE(S) | OXFORD UNIVERSITY INNOVATION LIMITED (Oxford, United Kingdom) |
INVENTOR(S) | Henry Snaith (Oxfordshire, United Kingdom); Tomas Leijtens (Oxfordshire, United Kingdom); Antonio Abate (Oxfordshire, United Kingdom); Alan Sellinger (Golden, Colorado) |
ABSTRACT | The present invention relates to the doping of organic semiconductors and processes for producing layers of p-doped organic semiconductors. Disclosed is a process for p-doping organic semiconductors comprising treating the organic semiconductor with an oxidized salt of the organic semiconductor. A process for producing a layer of a p-doped organic semiconductor comprising producing a p-doped organic semiconductor by treating the organic semiconductor with an oxidized salt of the organic semiconductor; disposing a composition comprising a solvent and the p-doped organic semiconductor on a substrate; and removing the solvent is also described. Also disclosed is a process for producing a layer of a p-doped organic semiconductor comprising: disposing a composition comprising a solvent, the organic semiconductor and a protic ionic liquid on a substrate; and removing the solvent. A process for producing a semiconductor device comprising a process for doping an organic semiconductor according to the invention is also described. Finally, a high purity p-dopant composition is described. |
FILED | Friday, May 30, 2014 |
APPL NO | 14/894187 |
ART UNIT | 2897 — Semiconductors/Memory |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0029 (20130101) H01G 9/2013 (20130101) H01G 9/2027 (20130101) H01G 9/2059 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/002 (20130101) Original (OR) Class H01L 51/005 (20130101) H01L 51/006 (20130101) H01L 51/0035 (20130101) H01L 51/0036 (20130101) H01L 51/0056 (20130101) H01L 51/0059 (20130101) H01L 51/4226 (20130101) H01L 2251/305 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/542 (20130101) Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929365 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The University of Southern California (Los Angeles, California) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Michael Slootsky (Ann Arbor, Michigan); Mark E. Thompson (Anaheim Hills, California) |
ABSTRACT | Arrangements and techniques for providing organic emissive layers are provided, in which the emissive layer includes a first dopant having a dissociative energy level. A second dopant in the emissive layer provides a solid state sink energy level, to which doubly excited excitons and/or polarons may transition instead of to the dissociative energy level, thereby decreasing the undesirable effects of transitions to the dissociative energy level. |
FILED | Thursday, May 28, 2015 |
APPL NO | 14/724238 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1011 (20130101) C09K 2211/1088 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/5016 (20130101) H01L 51/5028 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929461 | Zaghloul et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Sec. of Army (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Amir I. Zaghloul (Bethesda, Maryland); William T. Fraser (Edgewater, Maryland); Theodore K. Anthony (Randallstown, Maryland); Andrew J. Bayba (Beltsville, Maryland) |
ABSTRACT | An antenna having an elongated housing open at one end and defining an interior chamber. A telescoping mast has a carrier attached at a first end and a flexible antenna attached at its other end. The carrier with the attached mast and antenna is movable between a storage position in which the carrier, mast, and antenna are contained within the interior chamber of the housing, and a deployed position in which the mast and attached antenna protrude outwardly from the housing. A spring is positioned between the carrier and the housing which urges the carrier towards its deployed position. A catch mechanism selectively holds the carrier in its stored position and, when released, releases the spring to move the antenna to its deployed position. |
FILED | Thursday, September 21, 2017 |
APPL NO | 15/710919 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/10 (20130101) H01Q 1/36 (20130101) Original (OR) Class H01Q 1/088 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929466 | Gupta et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
INVENTOR(S) | Arpit K. Gupta (San Diego, California); James Buckwalter (San Clemente, California) |
ABSTRACT | Methods and apparatus, including computer program products are provided for self-steering antennas. In one aspect, there is a method. The method may include receiving, at a plurality of antennas, phase shifted versions of a signal. The method may further include determining a phase relationship between the phase shifted versions of the signal. Based on the determined phase relationship, the method may include adjusting a phase of a first local oscillator to remove a phase difference between the phase shifted versions of the signal to change the phase shifted versions of the signal to being in-phase versions of the signal. The method may further include combining the in-phase versions of the signal to steer a beam to a transmitter. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/775556 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/34 (20130101) H01Q 3/42 (20130101) H01Q 3/2605 (20130101) H01Q 3/2652 (20130101) Original (OR) Class Wireless Communication Networks H04W 40/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929690 | Lenert et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Andrej Lenert (Ann Arbor, Michigan); David Bierman (Cambridge, Massachusetts); Walker Chan (Princeton, New Jersey); Ivan Celanovic (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Evelyn N. Wang (Cambridge, Massachusetts); Young Suk Nam (Yongin, South Korea); Kenneth McEnaney (Cornish, New Hampshire); Daniel Kraemer (Providence, Rhode Island); Gang Chen (Carlisle, Massachusetts) |
ABSTRACT | A solar thermal photovoltaic device, and method of forming same, includes a solar absorber and a spectrally selective emitter formed on either side of a thermally conductive substrate. The solar absorber is configured to absorb incident solar radiation. The solar absorber and the spectrally selective emitter are configured with an optimized emitter-to-absorber area ratio. The solar thermal photovoltaic device also includes a photovoltaic cell in thermal communication with the spectrally selective emitter. The spectrally selective emitter is configured to permit high emittance for energies above a bandgap of the photovoltaic cell and configured to permit low emittance for energies below the bandgap. |
FILED | Friday, October 31, 2014 |
APPL NO | 14/529578 |
ART UNIT | 1758 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02164 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929725 | Jariwala et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Deep M. Jariwala (Evanston, Illinois); Vinod K. Sangwan (Syracuse, New York); Weichao Xu (Minneapolis, Minnesota); Hyungil Kim (Woodbury, Minnesota); Tobin J. Marks (Evanston, Illinois); Mark C. Hersam (Wilmette, Illinois) |
ABSTRACT | Van der Waals heterojunctions are extended to semiconducting p-type single-walled carbon nanotube (s-SWCNT) and n-type film that can be solution-processed with high spatial uniformity at the wafer scale. The resulting large-area, low-voltage p-n heterojunctions can exhibit anti-ambipolar transfer characteristics with high on/off ratios. The charge transport can be efficiently utilized in analog circuits such as frequency doublers and keying circuits that are widely used, for example, in telecommunication and wireless data transmission technologies. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/981245 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0017 (20130101) H01L 51/0048 (20130101) H01L 51/105 (20130101) H01L 51/0562 (20130101) H01L 2251/303 (20130101) Pulse Technique H03K 7/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09930325 | Ainspan et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Herschel A Ainspan (New Hempstead, New York); Seongwon Kim (Old Tappan, New Jersey); Franco Stellari (Waldwick, New Jersey); Alan J. Weger (Mohegan Lake, New York) |
ABSTRACT | Methods for testing the resolution of an imaging device include forming a plurality of semiconductor devices having proximal light emitting regions, such that the light emitting regions are grouped into distinct shapes separated by a distance governed by a target resolution size. The semiconductor devices are activated by providing an input signal. Light emissions from one or more of the activated semiconductor devices are suppressed by providing one or more select signals. |
FILED | Thursday, November 12, 2015 |
APPL NO | 14/939788 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) G01J 11/00 (20130101) G01J 2001/4238 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/26 (20130101) Pulse Technique H03K 19/14 (20130101) H03K 19/094 (20130101) Pictorial Communication, e.g Television H04N 17/002 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 09924913 | Majewski et al. |
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FUNDED BY |
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APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
ASSIGNEE(S) | West Virginia University (Morgantown, West Virginia) |
INVENTOR(S) | Stanislaw Majewski (Charlottesville, Virginia); Julie Brefczynski-Lewis (Morgantown, West Virginia) |
ABSTRACT | Various methods, systems and apparatus are provided for brain imaging during virtual reality stimulation. In one example, among others, a system for virtual ambulatory environment brain imaging includes a mobile brain imager configured to obtain positron emission tomography (PET) scans of a subject in motion, and a virtual reality (VR) system configured to provide one or more stimuli to the subject during the PET scans. In another example, a method for virtual ambulatory environment brain imaging includes providing stimulation to a subject through a virtual reality (VR) system; and obtaining a positron emission tomography (PET) scan of the subject while moving in response to the stimulation from the VR system. The mobile brain imager can be positioned on the subject with an array of imaging photodetector modules distributed about the head of the subject. |
FILED | Monday, May 22, 2017 |
APPL NO | 15/601158 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/462 (20130101) A61B 6/466 (20130101) A61B 6/467 (20130101) A61B 6/501 (20130101) A61B 6/4405 (20130101) Original (OR) Class A61B 6/5205 (20130101) A61B 34/30 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926195 | Arnold et al. |
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FUNDED BY |
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APPLICANT(S) | Michael S. Arnold (Ann Arbor, Michigan); Mark C. Hersam (Wilmette, Illinois); Samuel I. Stupp (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Michael S. Arnold (Ann Arbor, Michigan); Mark C. Hersam (Wilmette, Illinois); Samuel I. Stupp (Chicago, Illinois) |
ABSTRACT | The present teachings provide methods for providing populations of single-walled carbon nanotubes that are substantially monodisperse in terms of diameter, electronic type, and/or chirality. Also provided are single-walled carbon nanotube populations provided thereby and articles of manufacture including such populations. |
FILED | Friday, December 03, 2010 |
APPL NO | 12/959990 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 2202/02 (20130101) C01B 2202/22 (20130101) C01B 2202/36 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926547 | Spodsberg et al. |
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FUNDED BY |
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APPLICANT(S) | Nikolaj Spodsberg (Bagsvaerd, Denmark); Brett McBrayer (Sacramento, California); Pierre Cassland (Vellinge, Sweden) |
ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
INVENTOR(S) | Nikolaj Spodsberg (Bagsvaerd, Denmark); Brett McBrayer (Sacramento, California); Pierre Cassland (Vellinge, Sweden) |
ABSTRACT | The present invention relates to isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains. |
FILED | Thursday, April 26, 2012 |
APPL NO | 14/112022 |
ART UNIT | 1663 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Enzymes C12Y 302/01004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926622 | Erylimaz et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Osman L. Erylimaz (Plainfield, Illinois); Harpal Singh (Cuyahoga Falls, Ohio); Aaron C. Greco (Chicago, Illinois); Jair G. Ramirez Gonzalez (Naperville, Illinois); Ali Erdemir (Naperville, Illinois) |
ABSTRACT | A method for making a pitting resistant carbon coating that includes a hydrogenated diamond-like coating (“H-DLC”). The H-DLC is relatively soft and elastic. Unlike hard and/or inelastic coatings in the prior art, the present coatings do not exhibit a loss of adhesion (delamination). A bonding layer may be deposited on a metallic substrate and the deposited H-DLC on the bonding layer. |
FILED | Thursday, November 12, 2015 |
APPL NO | 14/939604 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/25 (20170801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/021 (20130101) C23C 14/024 (20130101) C23C 14/35 (20130101) C23C 14/0605 (20130101) C23C 14/0611 (20130101) Original (OR) Class C23C 14/0635 (20130101) C23C 14/3485 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926791 | Cairo et al. |
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FUNDED BY |
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APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Ronald Ralph Cairo (Simpsonville, South Carolina); Paul Stephen Dimascio (Greer, South Carolina); Jason Robert Parolini (Greer, South Carolina) |
ABSTRACT | A ceramic matrix composite article and a process of fabricating a ceramic matrix composite are disclosed. The ceramic matrix composite article includes a matrix distribution pattern formed by a manifold and ceramic matrix composite plies laid up on the matrix distribution pattern, includes the manifold, or a combination thereof. The manifold includes one or more matrix distribution channels operably connected to a delivery interface, the delivery interface configured for providing matrix material to one or more of the ceramic matrix composite plies. The process includes providing the manifold, forming the matrix distribution pattern by transporting the matrix material through the manifold, and contacting the ceramic matrix composite plies with the matrix material. |
FILED | Friday, December 04, 2015 |
APPL NO | 14/959307 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2709/04 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/282 (20130101) Original (OR) Class F01D 5/284 (20130101) F01D 9/02 (20130101) F01D 9/04 (20130101) F01D 25/24 (20130101) F01D 25/30 (20130101) Jet-propulsion Plants F02K 1/82 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/6033 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1317 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926891 | Zurlo et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | James Richard Zurlo (Madison, Wisconsin); Kenneth Edward Neuman (Waukesha, Wisconsin); Kevin Paul Konkle (West Bend, Wisconsin); Brian Joseph Murphy (Pewaukee, Wisconsin) |
ABSTRACT | A system includes an exhaust gas an exhaust gas recirculation (EGR) mixer which includes a housing and a first passage in the housing. The first passage may be configured to supply an EGR flow into the housing. The system further includes a second passage in the housing, such that the second passage is disposed about the first passage. The second passage is configured to supply at least one fluid flow into the housing. The system also includes a region downstream from the first and second passages, and a fluid outlet downstream from the region. |
FILED | Wednesday, November 18, 2015 |
APPL NO | 14/945322 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Lubricating of Machines or Engines in General; Lubricating Internal Combustion Engines; Crankcase Ventilating F01M 2013/0038 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 25/06 (20130101) F02M 26/06 (20160201) F02M 26/17 (20160201) F02M 26/18 (20160201) F02M 26/19 (20160201) Original (OR) Class F02M 26/36 (20160201) F02M 26/50 (20160201) F02M 35/10222 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927155 | Boeder et al. |
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APPLICANT(S) | Astronautics Corporation of America (Milwaukee, Wisconsin) |
ASSIGNEE(S) | ASTRONAUTICS CORPORATION OF AMERICA (Milwaukee, Wisconsin) |
INVENTOR(S) | Andre Michael Boeder (Monona, Wisconsin); Jeremy Jonathan Chell (Madison, Wisconsin); Steve Alan Jacobs (Madison, Wisconsin); John Paul Leonard (Cambridge, Wisconsin); Jon Jay Auringer (Poynette, Wisconsin); Carl Bruno Zimm (Madison, Wisconsin); Bryant Wayne Mueller (Madison, Wisconsin) |
ABSTRACT | A magnetic refrigeration apparatus includes beds of magnetocaloric material with a hot side and a cold side. The apparatus also includes a magnet to apply a magnetic field to the beds, a heat transfer fluid, a pump to circulate the heat transfer fluid, a hot side heat exchanger, a cold side heat exchanger, and a controller to control the flow of heat transfer fluid from the cold side to the hot side of the beds when the magnetic field on the beds is high at an average flow rate of ΦH for a duration ΔtH. The controller also controls the flow of heat transfer fluid from the hot side of the beds to the cold side of the beds when the magnetic field on the beds is low at an average flow rate of ΦC for a duration ΔtC, where ΔtC>ΔtH and ΦC<ΦH. |
FILED | Thursday, December 11, 2014 |
APPL NO | 14/567835 |
ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 2321/0022 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/66 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927178 | Srinivas et al. |
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FUNDED BY |
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APPLICANT(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
INVENTOR(S) | Girish Srinivas (Broomfield, Colorado); Steven Charles Gebhard (Golden, Colorado); Robert James Copeland (Metairie, Louisiana); David P. Eisenberg (Denver, Colorado) |
ABSTRACT | A seasonal process that captures stores and uses water in an ambient temperature-dependent manner to improve the efficiency of a natural gas power plant, comprising: (a) providing a natural gas power plant, the natural gas power plant having a flue gas stream, a cooling tower, and a gas turbine; (b) providing a water collection system; (c) providing a water storage facility; wherein the flue gas stream comprises uncondensed water vapor; wherein the water collection system is operably connected to the flue gas stream and the flue gas stream is directed to flow, at least in part, into the water collection system; wherein the water collection system is operably connected to the water storage facility; wherein the water storage facility is operably connected to the cooling tower and the water storage facility is operably connected to the gas turbine; wherein the process comprises the following steps of condensing flue gas water or using water that has been condensed from the flue gas stream based on outdoor ambient dry bulb temperature: (I) Only condensing water from the flue gas stream to produce a condensed water stream if outdoor ambient dry bulb temperature is less than 85° F.; (II) Only using condensed water to spray cool the cooling tower if outdoor ambient dry bulb temperature is at least 85° F.; (III) Only using condensed water to fog cool the gas turbine if outdoor ambient dry bulb temperature is at least 55° F.; wherein condensed water that is not immediately used to cool the cooling tower or to fog cool the gas turbine is stored in the water storage facility; and wherein the process uses a total amount of water on an annual basis to cool the cooling tower and to fog cool the gas turbine that does not exceed the annual amount of water condensed from the flue gas stream. Optionally, the process has a cooling tower that is a dry cooling tower and condensed water is used to spray cool the dry cooling tower, or the cooling tower is a wet cooling tower, or the cooling tower is a hybrid wet-dry cooling tower. The process may further comprise a water collection system having a three stage desiccant cycle and a calcium chloride desiccant that recovers at least about 60 wt % of the water from the flue gas, operates at or above ambient pressure or comprises plastic piping or plastic vessels. Or the process may further comprise using a water collection system having at least one direct contact condensing column that recovers at least about 60 wt % of the water from the flue gas, operates at or above ambient pressure or comprises plastic piping or plastic vessels. Or the process may further comprise using a water collection system having at least one direct contact condenser and a rotating wheel heat exchanger that recovers at least about 60 wt % of the water from the flue gas, operates at or above ambient pressure, or further comprises plastic piping or plastic vessels. The coefficient of performance for the cooling process is optionally at least 2.0. |
FILED | Sunday, May 08, 2016 |
APPL NO | 15/149152 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 9/003 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/31 (20130101) F05D 2220/32 (20130101) F05D 2260/213 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction F28C 1/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927352 | Birarda et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Giovanni Birarda (Trieste, Italy); Alexander Probst (Koesslam, Germany); Hoi-Ying Holman (Oakland, California) |
ABSTRACT | Methods are described herein and termed Microbial Community Screening and Profiling (MCSP) for multi-dimensional analysis and non-destructive and label-free detection and analysis, which allow for complementary analytical techniques to be performed on the same sample for such multidimensional analysis. |
FILED | Friday, November 21, 2014 |
APPL NO | 14/550904 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1463 (20130101) G01N 21/35 (20130101) Original (OR) Class G01N 21/65 (20130101) G01N 2021/3595 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927397 | Brueck et al. |
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FUNDED BY |
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APPLICANT(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Jeremy Scott Edwards (Albuquerque, New Mexico); Alexander Neumann (Albuquerque, New Mexico); Yuliya Kuznetsova (Albuquerque, New Mexico); Edgar A. Mendoza (Redondo Beach, California); C. Jeffrey Brinker (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Jeremy Scott Edwards (Albuquerque, New Mexico); Alexander Neumann (Albuquerque, New Mexico); Yuliya Kuznetsova (Albuquerque, New Mexico); Edgar A. Mendoza (Redondo Beach, California); C. Jeffrey Brinker (Albuquerque, New Mexico) |
ABSTRACT | Methods and apparatus for long read, label-free, optical nanopore long chain molecule sequencing. In general, the present disclosure describes a novel sequencing technology based on the integration of nanochannels to deliver single long-chain molecules with widely spaced (>wavelength), ˜1-nm aperture “tortuous” nanopores that slow translocation sufficiently to provide massively parallel, single base resolution using optical techniques. A novel, directed self-assembly nanofabrication scheme using simple colloidal nanoparticles is used to form the nanopore arrays atop nanochannels that unfold the long chain molecules. At the surface of the nanoparticle array, strongly localized electromagnetic fields in engineered plasmonic/polaritonic structures allow for single base resolution using optical techniques. |
FILED | Wednesday, November 26, 2014 |
APPL NO | 14/555453 |
ART UNIT | 1757 — Printing/Measuring and Testing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 2200/0663 (20130101) B01L 2400/0421 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927533 | Coleman et al. |
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FUNDED BY |
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APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
INVENTOR(S) | Jody Rustyn Coleman (Aiken, South Carolina); Eduardo B. Farfan (Aiken, South Carolina) |
ABSTRACT | An instrument for assaying radiation includes a radiation sensor and a collimator that covers at least a portion of the radiation sensor. The collimator defines a first field of view to the radiation sensor. An insert in the collimator defines a second field of view to the radiation sensor that is less than the first field of view. |
FILED | Tuesday, February 05, 2013 |
APPL NO | 13/759372 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/02 (20130101) Measurement of Nuclear or X-radiation G01T 1/169 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/04 (20130101) G21K 1/025 (20130101) G21K 1/046 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927549 | Aldridge et al. |
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FUNDED BY |
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APPLICANT(S) | CARBO Ceramics Inc. (Houston, Texas); SANDIA CORPORATION (Albuquerque, New Mexico) |
ASSIGNEE(S) | CARBO Ceramics Inc. (Houston, Texas); Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | David F. Aldridge (Albuquerque, New Mexico); Lewis C. Bartel (Albuquerque, New Mexico) |
ABSTRACT | Born Scattering Inversion (BSI) systems and methods are disclosed. A BSI system may be incorporated in a well system for accessing natural gas, oil and geothermal reserves in a geologic formation beneath the surface of the Earth. The BSI system may be used to generate a three-dimensional image of a proppant-filled hydraulically-induced fracture in the geologic formation. The BSI system may include computing equipment and sensors for measuring electromagnetic fields in the vicinity of the fracture before and after the fracture is generated, adjusting the parameters of a first Born approximation model of a scattered component of the surface electromagnetic fields using the measured electromagnetic fields, and generating the image of the proppant-filled fracture using the adjusted parameters. |
FILED | Thursday, July 03, 2014 |
APPL NO | 14/323674 |
ART UNIT | 2865 — Printing/Measuring and Testing |
CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/26 (20130101) G01V 3/30 (20130101) Original (OR) Class G01V 3/38 (20130101) G01V 99/00 (20130101) G01V 99/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927616 | Hsu et al. |
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FUNDED BY |
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APPLICANT(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Chicago, Illinois); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Chicago, Illinois); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | Transparent displays enable many useful applications, including heads-up displays for cars and aircraft as well as displays on eyeglasses and glass windows. Unfortunately, transparent displays made of organic light-emitting diodes are typically expensive and opaque. Heads-up displays often require fixed light sources and have limited viewing angles. And transparent displays that use frequency conversion are typically energy inefficient. Conversely, the present transparent displays operate by scattering visible light from resonant nanoparticles with narrowband scattering cross sections and small absorption cross sections. More specifically, projecting an image onto a transparent screen doped with nanoparticles that selectively scatter light at the image wavelength(s) yields an image on the screen visible to an observer. Because the nanoparticles scatter light at only certain wavelengths, the screen is practically transparent under ambient light. Exemplary transparent scattering displays can be simple, inexpensive, scalable to large sizes, viewable over wide angular ranges, energy efficient, and transparent simultaneously. |
FILED | Tuesday, August 16, 2016 |
APPL NO | 15/237800 |
ART UNIT | 2875 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/0242 (20130101) G02B 5/0278 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/0112 (20130101) G02B 2027/0145 (20130101) G02B 2027/0147 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927706 | Nealey et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Paul Franklin Nealey (Chicago, Illinois); Tzu-Hsuan Chang (Madison, Wisconsin); Shisheng Xiong (Darien, Illinois); Zhenqiang Ma (Middleton, Wisconsin); Michael Scott Arnold (Middleton, Wisconsin); Robert Jacobberger (Madison, Wisconsin) |
ABSTRACT | Provided herein are methods of directed self-assembly (DSA) on atomic layer chemical patterns and related compositions. The atomic layer chemical patterns may be formed from two-dimensional materials such as graphene. The atomic layer chemical patterns provide high resolution, low defect directed self-assembly. For example, DSA on a graphene pattern can be used achieve ten times the resolution of DSA that is achievable on a three-dimensional pattern such as a polymer brush. Assembly of block copolymers on the atomic layer chemical patterns may also facilitate subsequent etch, as the atomic layer chemical patterns are easier to etch than conventional pattern materials. |
FILED | Wednesday, July 20, 2016 |
APPL NO | 15/215016 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 153/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/0227 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/002 (20130101) G03F 7/165 (20130101) Original (OR) Class G03F 7/168 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32009 (20130101) H01J 2237/334 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02527 (20130101) H01L 21/02568 (20130101) H01L 21/3081 (20130101) H01L 21/3086 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928033 | Merrill |
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APPLICANT(S) | NVIDIA CORPORATION (Santa Clara, California) |
ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
INVENTOR(S) | Duane Merrill (Charlottesville, Virginia) |
ABSTRACT | One embodiment of the present invention performs a parallel prefix scan in a single pass that incorporates variable look-back. A parallel processing unit (PPU) subdivides a list of inputs into sequentially-ordered segments and assigns each segment to a streaming multiprocessor (SM) included in the PPU. Notably, the SMs may operate in parallel. Each SM executes write operations on a segment descriptor that includes the status, aggregate, and inclusive-prefix associated with the assigned segment. Further, each SM may execute read operations on segment descriptors associated with other segments. In operation, each SM may perform reduction operations to determine a segment-wide aggregate, may perform look-back operations across multiple preceding segments to determine an exclusive-prefix, and may perform a scan seeded with the exclusive prefix to generate output data. Advantageously, the PPU performs one read operation per input, thereby reducing the time required to execute the prefix scan relative to prior-art parallel implementations. |
FILED | Tuesday, October 01, 2013 |
APPL NO | 14/043626 |
ART UNIT | 2199 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 7/506 (20130101) Original (OR) Class G06F 8/456 (20130101) G06F 2207/5063 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928104 | Dally et al. |
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FUNDED BY |
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APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
INVENTOR(S) | William J. Dally (Los Altos Hills, California); James David Balfour (Mountain View, California); Ignacio Llamas Ubieto (Sunnyvale, California) |
ABSTRACT | A system, method, and computer program product are provided for accessing a queue. The method includes receiving a first request to reserve a data record entry in a queue, updating a queue state block based on the first request, and returning a response to the request. A second request is received to commit the data record entry and the queue state block is updated based on the second request. |
FILED | Wednesday, June 19, 2013 |
APPL NO | 13/922189 |
ART UNIT | 2184 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 9/466 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928202 | Hoff |
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FUNDED BY |
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APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
ASSIGNEE(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
INVENTOR(S) | James R. Hoff (Wheaton, Illinois) |
ABSTRACT | A two-to-one multiplexor comprises a first data input configured to hold data provided from a first preceding asynchronous pipeline stage and a second data input configured to hold data provided from a second preceding asynchronous pipeline stage, a 4-phase bundled data protocol facilitating communication between the first and the second data inputs and the first and second preceding asynchronous pipeline stage, an arbitration unit connected to the first data input and the second data input, and configured to select which of the data from the first and the second data inputs is released, a request release unit, and a reset unit wherein the arbitration unit, the request release unit, and the reset unit implement and complete a second 4-phase bundled data protocol facilitating communication with a succeeding asynchronous pipeline stage for transmission of the data chosen by the arbitration unit thereby providing asynchronous multiplexing of the data. |
FILED | Thursday, April 21, 2016 |
APPL NO | 15/134520 |
ART UNIT | 2414 — Multiplex and VoIP |
CURRENT CPC | Electric Digital Data Processing G06F 13/42 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928827 | El-Kady et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Ihab Fathy El-Kady (Albuquerque, New Mexico); Edward S. Bielejec (Albuquerque, New Mexico); Charles M. Reinke (Albuquerque, New Mexico); Susan M. Clark (Albuquerque, New Mexico) |
ABSTRACT | A quantum device includes a phononic crystal defined on a semiconductor substrate. Phononic cavities are defined in the phononic crystal, wherein each phononic cavity contains an implanted acceptor atom. Phononic waveguides are defined in the phononic crystal, wherein each waveguide is coupled to at least one phononic cavity. At least some phononic waveguides are arranged to provide coupling between phononic cavities and ultrasonic transducers. At least some phononic waveguides are arranged to provide coupling between different phononic cavities. |
FILED | Thursday, March 03, 2016 |
APPL NO | 15/060434 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 15/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929209 | Herget et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Philipp Herget (San Jose, California); Eugene J. O'Sullivan (Nyack, New York); Lubomyr T. Romankiw (Briarcliff Manor, New York); Naigang Wang (Ossining, New York); Bucknell C. Webb (Yorktown Heights, New York) |
ABSTRACT | A mechanism is provided for an integrated laminated magnetic device. A substrate and a multilayer stack structure form the device. The multilayer stack structure includes alternating magnetic layers and diode structures formed on the substrate. Each magnetic layer in the multilayer stack structure is separated from another magnetic layer in the multilayer stack structure by a diode structure. |
FILED | Wednesday, January 25, 2017 |
APPL NO | 15/414997 |
ART UNIT | 2897 — Semiconductors/Memory |
CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/14708 (20130101) H01F 10/14 (20130101) H01F 27/24 (20130101) H01F 27/2804 (20130101) H01F 2027/2809 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/22 (20130101) Original (OR) Class H01L 28/10 (20130101) H01L 43/02 (20130101) H01L 43/10 (20130101) H01L 43/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929293 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Jin K. Kim (Albuquerque, New Mexico); John F. Klem (Albuquerque, New Mexico); Eric A. Shaner (Rio Rancho, New Mexico); Benjamin Varberg Olson (Albuquerque, New Mexico); Emil Andrew Kadlec (Albuquerque, New Mexico); Anna Tauke-Pedretti (Albuquerque, New Mexico); Torben Ray Fortune (Albuquerque, New Mexico) |
ABSTRACT | In a superlattice (SL) photodetector, each period of the SL includes first and second semiconductor layers having different compositions, at least one of which comprises indium arsenide (InAs). At least one of these two semiconductor layers has a graded composition. In embodiments, the first semiconductor layer comprises InAs and the second semiconductor layer is a graded layer comprising indium arsenide antimonide (InAsSb), wherein the antimony (Sb) concentration is varied. In examples, the Sb concentration in the second layer gradually increases from the top and bottom toward the middle of the layer. |
FILED | Tuesday, April 04, 2017 |
APPL NO | 15/479134 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/109 (20130101) H01L 31/03046 (20130101) H01L 31/022408 (20130101) H01L 31/035236 (20130101) Original (OR) Class H01L 31/035281 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929296 | Rose |
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FUNDED BY |
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APPLICANT(S) | Douglas H. Rose (San Jose, California) |
ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
INVENTOR(S) | Douglas H. Rose (San Jose, California) |
ABSTRACT | One embodiment relates to a bifacial photovoltaic module having an edge reflector. The module includes a plurality of solar cells in an array, each solar cell having a front side and a back side. A reflector is configured on an edge of the array of solar cells, the first reflector being configured to reflect light onto the front side of a row of solar cells adjacent to the edge. Another embodiment relates to a method of reducing non-uniformity of power generation from a bifacial photovoltaic module. Electrical current produced from solar cells along at least one edge of the array is increased by using a reflective strip facing towards the front side of the solar cells along the edge. Another embodiment relates to a bifacial photovoltaic module having an edge refractor. Other embodiments and features are also disclosed. |
FILED | Tuesday, December 22, 2009 |
APPL NO | 12/644609 |
ART UNIT | 1756 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/048 (20130101) H01L 31/056 (20141201) Original (OR) Class H01L 31/0352 (20130101) H01L 31/0547 (20141201) H01L 31/02363 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929338 | Shi et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents Of The University Of California (Oakland, California) |
ASSIGNEE(S) | The Regents Of The University Of California (Oakland, California) |
INVENTOR(S) | Jing Shi (Riverside, California); Junxue Li (Riverside, California); Yadong Xu (Riverside, California); Mohammed Aldosary (Riverside, California); Chi Tang (Riverside, California); Roger Lake (Riverside, California) |
ABSTRACT | Pure spin current devices are provided. The devices include sandwich structures of metal/magnetic insulator/metal. A first current injected in a first metal layer generates a pure spin current. The spin current can be switched between “on” and “off” states by controlling an in-plane magnetization orientation of the magnetic insulator. In the “on” state, the pure spin current is transmitted from the first metal layer to the second metal layer, through the magnetic insulator layer. The pure spin current in the second metal layer induces generation of a second charge current. In the “off” state, the pure spin current is absorbed at the interface between the first metal layer and the metal insulator. Such structures can serve as pure spin current valve devices or provide analog functionality, as rotating the in-plane magnetization provides analog sinusoidal modulation of the spin current. |
FILED | Monday, October 10, 2016 |
APPL NO | 15/289850 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 37/00 (20130101) H01L 43/04 (20130101) Original (OR) Class H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/14 (20130101) H01L 43/065 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929365 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The University of Southern California (Los Angeles, California) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Michael Slootsky (Ann Arbor, Michigan); Mark E. Thompson (Anaheim Hills, California) |
ABSTRACT | Arrangements and techniques for providing organic emissive layers are provided, in which the emissive layer includes a first dopant having a dissociative energy level. A second dopant in the emissive layer provides a solid state sink energy level, to which doubly excited excitons and/or polarons may transition instead of to the dissociative energy level, thereby decreasing the undesirable effects of transitions to the dissociative energy level. |
FILED | Thursday, May 28, 2015 |
APPL NO | 14/724238 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1011 (20130101) C09K 2211/1088 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/5016 (20130101) H01L 51/5028 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929400 | Rios et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Orlando Rios (Knoxville, Tennessee); Claus Daniel (Knoxville, Tennessee); Wyatt Evan Tenhaeff (Rochester, New York); Surendra K. Martha (Knoxville, Tennessee) |
ABSTRACT | A composite Si-carbon fiber comprising a carbon matrix material with 1-90 wt % silicon embedded therein. The composite carbon fibers are incorporated into electrodes for batteries. The battery can be a lithium ion battery. A method of making an electrode incorporating composite Si-carbon fibers is also disclosed. |
FILED | Monday, September 09, 2013 |
APPL NO | 14/021743 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/362 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/587 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2918 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929429 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | Jun Liu (Richland, Washington); Yuliang Cao (Wuhan, China PRC); Lifen Xiao (Wuhan, China PRC); Jie Xiao (Richland, Washington); Gregory J. Exarhos (Richland, Washington); Birgit Schwenzer (Richland, Washington); Zimin Nie (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Jun Liu (Richland, Washington); Yuliang Cao (Wuhan, China PRC); Lifen Xiao (Wuhan, China PRC); Jie Xiao (Richland, Washington); Gregory J. Exarhos (Richland, Washington); Birgit Schwenzer (Richland, Washington); Zimin Nie (Richland, Washington) |
ABSTRACT | Composite materials containing sulfurized polymers and sulfur-containing particles can be used in lithium-sulfur energy storage devices as a positive electrode. The composite material exhibits relatively high capacity retention and high charge/discharge cycle stability. In one particular instance, the composite comprises a sulfurized polymer having chains that are cross-linked through sulfur bonds. The polymer provides a matrix in which sulfide and/or polysulfide intermediates formed during electrochemical charge-discharge processes of sulfur can be confined through chemical bonds and not mere physical confinement or sorption. |
FILED | Monday, July 30, 2012 |
APPL NO | 13/561701 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 34/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) H01B 1/127 (20130101) H01B 1/128 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/362 (20130101) H01M 4/364 (20130101) H01M 4/382 (20130101) H01M 4/606 (20130101) H01M 4/625 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
09929432 — Low temperature sulfur and sodium metal battery for grid-scale energy storage application
US 09929432 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Gao Liu (Piedmont, California); Dongdong Wang (Berkeley, California) |
ABSTRACT | A re-chargeable battery comprising a non-dendrite forming sodium (Na)/potassium (K) liquid metal alloy anode, a sulfur and polyacrylonitrile (PAN) conductive polymer composite cathode, a polyethyleneoxide (PEO) solid electrolyte, a solid electrolyte interface (SEI) formed on the PEO solid electrolyte; and a cell housing, wherein the anode, cathode, and electrolyte are assembled into the cell housing with the PEO solid electrolyte disposed between the cathode and anode. |
FILED | Friday, March 15, 2013 |
APPL NO | 14/385030 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) H01M 2/1673 (20130101) H01M 4/40 (20130101) H01M 4/604 (20130101) H01M 4/661 (20130101) H01M 10/054 (20130101) Original (OR) Class H01M 10/056 (20130101) H01M 10/0565 (20130101) H01M 10/3918 (20130101) H01M 10/3954 (20130101) H01M 2300/002 (20130101) H01M 2300/0082 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929453 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Jun Lu (Bolingbrook, Illinois); Khalil Amine (Oakbrook, Illinois); Xiaoping Wang (Naperville, Illinois); Xiangyi Luo (Westmont, Illinois); Deborah J. Myers (Lisle, Illinois) |
ABSTRACT | A lithium-air battery cathode catalyst includes core-shell nanoparticles on a carbon support, wherein: a core of the core-shell nanoparticles is platinum metal; and a shell of the core-shell nanoparticles is copper metal; wherein: the core-shell nanoparticles have a weight ratio of the copper metal to the platinum metal from about 4% to about 6% copper to from about 2% to about 12% platinum, with a remaining percentage being the carbon support. |
FILED | Monday, August 04, 2014 |
APPL NO | 14/450772 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 4/921 (20130101) H01M 4/926 (20130101) H01M 4/9041 (20130101) H01M 12/08 (20130101) Original (OR) Class H01M 2004/8689 (20130101) H01M 2300/0028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/128 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929690 | Lenert et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Andrej Lenert (Ann Arbor, Michigan); David Bierman (Cambridge, Massachusetts); Walker Chan (Princeton, New Jersey); Ivan Celanovic (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Evelyn N. Wang (Cambridge, Massachusetts); Young Suk Nam (Yongin, South Korea); Kenneth McEnaney (Cornish, New Hampshire); Daniel Kraemer (Providence, Rhode Island); Gang Chen (Carlisle, Massachusetts) |
ABSTRACT | A solar thermal photovoltaic device, and method of forming same, includes a solar absorber and a spectrally selective emitter formed on either side of a thermally conductive substrate. The solar absorber is configured to absorb incident solar radiation. The solar absorber and the spectrally selective emitter are configured with an optimized emitter-to-absorber area ratio. The solar thermal photovoltaic device also includes a photovoltaic cell in thermal communication with the spectrally selective emitter. The spectrally selective emitter is configured to permit high emittance for energies above a bandgap of the photovoltaic cell and configured to permit low emittance for energies below the bandgap. |
FILED | Friday, October 31, 2014 |
APPL NO | 14/529578 |
ART UNIT | 1758 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02164 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09930806 | Chainer et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); David P. Graybill (Staatsburg, New York); Madhusudan K. Iyengar (Foster City, California); Vinod Kamath (Raleigh, North Carolina); Bejoy J. Kochuparambil (Apex, North Carolina); Roger R. Schmidt (Poughkeepsie, New York); Mark E. Steinke (Durham, North Carolina) |
ABSTRACT | Apparatus and method are provided for facilitating cooling of an electronic component. The apparatus includes a liquid-cooled cold plate and a thermal spreader associated with the cold plate. The cold plate includes multiple coolant-carrying channel sections extending within the cold plate, and a thermal conduction surface with a larger surface area than a surface area of the component to be cooled. The thermal spreader includes one or more heat pipes including multiple heat pipe sections. One or more heat pipe sections are partially aligned to a first region of the cold plate, that is, where aligned to the surface to be cooled, and partially aligned to a second region of the cold plate, which is outside the first region. The one or more heat pipes facilitate distribution of heat from the electronic component to coolant-carrying channel sections of the cold plate located in the second region of the cold plate. |
FILED | Thursday, November 21, 2013 |
APPL NO | 14/086114 |
ART UNIT | 3744 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/02 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20336 (20130101) Original (OR) Class H05K 7/20509 (20130101) H05K 7/20772 (20130101) H05K 7/20936 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09930807 | Chainer et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); David P. Graybill (Staatsburg, New York); Madhusudan K. Iyengar (Foster City, California); Vinod Kamath (Raleigh, North Carolina); Bejoy J. Kochuparambil (Apex, North Carolina); Roger R. Schmidt (Pougkeepsie, New York); Mark E. Steinke (Durham, North Carolina) |
ABSTRACT | Methods are provided for facilitating cooling of an electronic component. The method includes providing a liquid-cooled cold plate and a thermal spreader associated with the cold plate. The cold plate includes multiple coolant-carrying channel sections extending within the cold plate, and a thermal conduction surface with a larger surface area than a surface area of the component to be cooled. The thermal spreader includes one or more heat pipes including multiple heat pipe sections. One or more heat pipe sections are partially aligned to a first region of the cold plate, that is, where aligned to the surface to be cooled, and partially aligned to a second region of the cold plate, which is outside the first region. The one or more heat pipes facilitate distribution of heat from the electronic component to coolant-carrying channel sections of the cold plate located in the second region of the cold plate. |
FILED | Monday, December 08, 2014 |
APPL NO | 14/562879 |
ART UNIT | 3744 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/02 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20336 (20130101) Original (OR) Class H05K 7/20509 (20130101) H05K 7/20772 (20130101) H05K 7/20936 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 09925209 | DeAngelis |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma) |
INVENTOR(S) | Paul L. DeAngelis (Edmond, Oklahoma) |
ABSTRACT | Compositions containing conjugates of heparosan polymer with at least one drug are disclosed, along with methods of production and use thereof. |
FILED | Friday, November 07, 2014 |
APPL NO | 14/536003 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Original (OR) Class A61K 38/21 (20130101) A61K 38/22 (20130101) A61K 38/27 (20130101) A61K 38/28 (20130101) A61K 38/50 (20130101) A61K 38/193 (20130101) A61K 39/395 (20130101) A61K 47/61 (20170801) A61K 2039/505 (20130101) Enzymes C12Y 305/01001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925213 | Gellman et al. |
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FUNDED BY |
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APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
INVENTOR(S) | Samuel H. Gellman (Madison, Wisconsin); Shannon S. Stahl (Madison, Wisconsin); Brendan P. Mowery (San Marcos, California); Annelise Barron (Palo Alto, California); Michelle Dohm (Palos Park, Illinois) |
ABSTRACT | Non-natural oligomers have recently shown promise as functional analogs of lung surfactant proteins B and C (SP-B and SP-C), two helical and amphiphilic proteins that are critical for normal respiration. The generation of non-natural mimics of SP-B and SP-C has previously been restricted to step-by-step, sequence-specific synthesis, which results in discrete oligomers that are intended to manifest specific structural attributes. Presented herein an alternative approach to SP-B mimicry that is based on sequence-random copolymers containing cationic and lipophilic subunits. These materials, members of the nylon-3 family, are prepared by ring-opening polymerization of β-lactams. The best of the nylon-3 polymers display promising in vitro surfactant activities in a mixed lipid film. Pulsating bubble surfactometry data indicate that films containing the most surface-active polymers attain adsorptive and dynamic-cycling properties that surpass those of discrete peptides intended to mimic SP-B. Attachment of an N-terminal octadecanoyl unit to the nylon-3 copolymers affords further improvements by reducing the percent surface area compression to reach low minimum surface tension. |
FILED | Friday, May 01, 2015 |
APPL NO | 14/701775 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0082 (20130101) A61K 31/785 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925223 | Kaznessis et al. |
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FUNDED BY |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Yiannis J. Kaznessis (New Brighton, Minnesota); Katherine G. Volzing (Princeton, New Jersey); Juan Borrero Del Pino (Cork, Ireland); Gary Dunny (Minneapolis, Minnesota) |
ABSTRACT | Provided herein are genetically modified microbes. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide comprising a pheromone-responsive region. In one embodiment, the pheromone-responsive region is derived from a conjugative plasmid from a member of the genus Enterococcus spp. The pheromone-responsive region includes a pheromone-responsive promoter and an operably linked coding region encoding an antimicrobial peptide. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide comprising a promoter and an operably linked coding sequence encoding an antimicrobial peptide, where expression of the coding region is controlled by a modulator polypeptide and is altered by a modulating agent, and where the coding region encodes an antimicrobial peptide. Also provided herein are methods of using the genetically modified microbes, including methods for inhibiting growth of an Enterococcus spp., a pathogenic E. coli, or a pathogenic Salmonella spp., for treating a subject, and for modifying a subject's gastrointestinal microflora. |
FILED | Wednesday, September 25, 2013 |
APPL NO | 14/431044 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/744 (20130101) Original (OR) Class A61K 38/10 (20130101) A61K 38/16 (20130101) A61K 2035/11 (20130101) Peptides C07K 7/08 (20130101) C07K 14/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/746 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925270 | Maynard et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Heather D. Maynard (Los Angeles, California); Thi Nguyen (Reseda, California) |
ABSTRACT | A heparin mimicking polymer, its conjugate with bFGF, and method of making and using the same are disclosed. In particular, described herein are conjugates of biologic agents (e.g., bFGF) and heparin mimicking polymers having superior stability while retaining full native activity after a variety of stressors. |
FILED | Wednesday, November 28, 2012 |
APPL NO | 14/361167 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/795 (20130101) A61K 38/1825 (20130101) A61K 47/48176 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925281 | Steinmetz et al. |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Nicole F. Steinmetz (Cleveland, Ohio); Michael Bruckman (Cleveland, Ohio); Lauren Randolph (State College, Pennsylvania) |
ABSTRACT | An imaging nanoparticle comprising a plant virus particle having an interior surface and an exterior surface, an imaging agent that is linked to the interior and/or exterior surface, and a layer of biocompatible mineral such as silica coated over the exterior surface, is described. The imaging nanoparticle can be used in method of generating an image of a tissue region of a subject, by administering to the subject a diagnostically effective amount of an imaging nanoparticle and generating an image of the tissue region of the subject to which the imaging nanoparticle has been distributed. |
FILED | Wednesday, August 05, 2015 |
APPL NO | 14/818812 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/085 (20130101) A61K 49/108 (20130101) A61K 49/1896 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925504 | Griffiths et al. |
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FUNDED BY |
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APPLICANT(S) | Andrew Griffiths (Strasbourg, France); David Weitz (Cambridge, Massachusetts); Keunho Ahn (San Diego, California); Darren Link (Guilford, Connecticut); Jerome Bibette (Paris, France) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Medical Research Council (London, United Kingdom) |
INVENTOR(S) | Andrew Griffiths (Strasbourg, France); David Weitz (Cambridge, Massachusetts); Keunho Ahn (San Diego, California); Darren Link (Guilford, Connecticut); Jerome Bibette (Paris, France) |
ABSTRACT | The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalizing two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalized into the microcapsules. |
FILED | Wednesday, December 20, 2006 |
APPL NO | 11/643151 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 5/0646 (20130101) B01F 5/0647 (20130101) B01F 5/0655 (20130101) B01F 13/0071 (20130101) Original (OR) Class B01F 13/0076 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/005 (20130101) B01J 2219/0086 (20130101) B01J 2219/00497 (20130101) B01J 2219/00576 (20130101) B01J 2219/00585 (20130101) B01J 2219/00596 (20130101) B01J 2219/00599 (20130101) B01J 2219/00707 (20130101) B01J 2219/00722 (20130101) B01J 2219/00725 (20130101) B01J 2219/00743 (20130101) B01J 2219/00853 (20130101) B01J 2219/00889 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/50273 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 3/502784 (20130101) B01L 2200/0605 (20130101) B01L 2200/0673 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/084 (20130101) B01L 2400/0406 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) Peptides C07K 1/047 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 40/10 (20130101) C40B 50/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2035/1034 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926194 | Panchapakesan |
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FUNDED BY |
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APPLICANT(S) | Balaji Panchapakesan (Louisville, Kentucky) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Balaji Panchapakesan (Louisville, Kentucky) |
ABSTRACT | A device and method detect cellular targets in a bodily source by utilizing a biofunctional pad comprised of a thin film of carbon nanotubes (CNT's). When antibodies are absorbed by the CNT's, cellular targets having markers matching the antibodies may be detected in a bodily source placed upon the biofunctional pad by measuring the conductivity of the thin film using conductive contacts electrically coupled to the thin film, as the binding of the receptors in the cellular targets to the antibodies changes the free energy in the thin film. In many respects, the device functions as a Field Effect Transistor (FET) with the bodily source, e.g., blood, acting as a polyelectrolyte liquid gate electrode to create a varying electrostatic charge or capacitance in the thin film based upon the binding of cellular targets in the source to the antibodies present on the biofunctional pad. |
FILED | Thursday, March 10, 2011 |
APPL NO | 13/045135 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Original (OR) Class B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4146 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1039 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926195 | Arnold et al. |
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FUNDED BY |
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APPLICANT(S) | Michael S. Arnold (Ann Arbor, Michigan); Mark C. Hersam (Wilmette, Illinois); Samuel I. Stupp (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Michael S. Arnold (Ann Arbor, Michigan); Mark C. Hersam (Wilmette, Illinois); Samuel I. Stupp (Chicago, Illinois) |
ABSTRACT | The present teachings provide methods for providing populations of single-walled carbon nanotubes that are substantially monodisperse in terms of diameter, electronic type, and/or chirality. Also provided are single-walled carbon nanotube populations provided thereby and articles of manufacture including such populations. |
FILED | Friday, December 03, 2010 |
APPL NO | 12/959990 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 2202/02 (20130101) C01B 2202/22 (20130101) C01B 2202/36 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926204 | Orlovskaya et al. |
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FUNDED BY |
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APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
INVENTOR(S) | Nina Orlovskaya (Orlando, Florida); Zhilin Xie (Orlando, Florida); Richard G. Blair (Oviedo, Florida) |
ABSTRACT | The presently disclosed and/or claimed inventive concept(s) relates generally to hexagonal osmium boride, OsB2, and methods of producing the same. In one non-limiting embodiment, hexagonal OsB2 is produced by mechanochemical synthesis of osmium and boron in a high energy ball mill. |
FILED | Thursday, January 16, 2014 |
APPL NO | 14/157216 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/645 (20130101) C04B 35/6261 (20130101) C04B 35/58064 (20130101) C04B 2235/76 (20130101) C04B 2235/80 (20130101) C04B 2235/666 (20130101) C04B 2235/761 (20130101) C04B 2235/767 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/5454 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 1/10 (20130101) C30B 29/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926293 | Stockwell et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Brent R. Stockwell (New York, New York); Matthew Welsch (New York, New York) |
ABSTRACT | The present invention provides, inter alia, compounds having the structure: wherein R7, R8 and n are as disclosed herein, that selectively bind a RAS protein at two or more sites and methods for their synthesis. Compositions and kits containing the compounds, as well as methods of using the compounds and compositions for ameliorating or treating the effects of a disease associated with altered RAS signaling, such as a cancer, in a subject and methods for effecting cancer cell death are also provided herein. Methods of identifying a multivalent compound which binds selectively to a target protein also are provided herein. |
FILED | Tuesday, March 22, 2016 |
APPL NO | 15/077865 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 209/14 (20130101) C07D 295/108 (20130101) C07D 401/12 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 403/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926347 | Alper et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Hal Alper (Austin, Texas); Eric Young (Arlington, Massachusetts) |
ABSTRACT | Provided herein are compositions and methods useful for transporting xylose, arabinose and other monosaccharides, into a yeast cell. |
FILED | Wednesday, November 05, 2014 |
APPL NO | 15/034772 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/39 (20130101) C07K 14/40 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926412 | Torkelson et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | John M. Torkelson (Skokie, Illinois); Cynthia Pierre (Chicago, Illinois); Amanda Flores Walker (Mt. Vernon, Indiana) |
ABSTRACT | Solid-state shear pulverization of semi-crystalline polymers and copolymers thereof and related methods for enhanced crystallization kinetics and physical/mechanical properties. |
FILED | Friday, September 11, 2015 |
APPL NO | 14/851856 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/88 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/12 (20130101) Original (OR) Class C08J 2323/06 (20130101) C08J 2323/12 (20130101) C08J 2367/02 (20130101) C08J 2367/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927334 | Murthy et al. |
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FUNDED BY |
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APPLICANT(S) | Shashi K. Murthy (Newton, Massachusetts); Adam Hatch (Cambridge, Massachusetts); George Hansmann (Boston, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Shashi K. Murthy (Newton, Massachusetts); Adam Hatch (Cambridge, Massachusetts); George Hansmann (Boston, Massachusetts) |
ABSTRACT | Disclosed herein are hydrogel compositions and methods of making hydrogel compositions. Furthermore, methods of specifically capturing and releasing biological materials from a sample using the disclosed hydrogel compositions are disclosed, including methods of utilizing the compositions in microfluidic devices. |
FILED | Friday, February 03, 2012 |
APPL NO | 13/982680 |
ART UNIT | 1677 — Printing/Measuring and Testing |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/061 (20130101) B01F 13/0059 (20130101) B01F 2005/0623 (20130101) B01F 2005/0636 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/069 (20130101) B01L 2300/0867 (20130101) B01L 2400/0478 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class G01N 33/548 (20130101) G01N 33/54386 (20130101) G01N 33/56966 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927336 | Meisberger et al. |
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FUNDED BY |
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APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Stephen P. Meisberger (Ithaca, New York); Matthew A. Warkentin (Ithaca, New York); Jesse B. Hopkins (Ithaca, New York); Andrea M. Katz (Ithaca, New York); Lois Pollack (Ithaca, New York); Robert E. Thorne (Ithaca, New York) |
ABSTRACT | Apparatus and methods for performing small angle X-ray scattering (SAXS) at low (cryogenic) temperatures for determining the structure of and changes in the structure of proteins, DNA, RNA, and other biological molecules and biomolecular assemblies and structures. A cryogenic, small angle X-ray scattering (SAXS) application sample holder, includes a sample cell including a base portion and at least two parallel walls disposed on the base, wherein the sample cell has a liquid volume capacity defined by the walls and the base portion of 0.001 to 10 microliters. A method for performing cryogenic SAXS on a sample includes the steps of providing a sample biomolecule solution containing an aqueous buffer, a biomolecule, and a cryoprotectant agent, wherein the cryoprotectant agent comprises up to 60% (w/w) of the biomolecule solution, and other known components as necessary to solubilize and stabilize the biomolecule, in a sample holder of claim 1, cryogenically cooling the sample solution in the sample holder at a rate equal to or greater than 100 K/sec without ice formation, and examining the cooled sample using small angle X-ray scattering by passing a beam of X-rays through the sample. |
FILED | Tuesday, June 04, 2013 |
APPL NO | 14/405253 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 23/201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927417 | Yakovlev et al. |
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FUNDED BY |
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APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
INVENTOR(S) | Vladislav Victorovich Yakovlev (College Station, Texas); Edward S. Fry (College Station, Texas); John David Mason (College Station, Texas); Joel Nathan Bixler (San Antonio, Texas); Michael Thomas Cone (Houston, Texas); Brett Harrison Hokr (Bryan, Texas) |
ABSTRACT | Disclosed is a high reflectivity integrating cavity and device to amplify and detect luminescent emissions produced by small concentrations of materials to be analyzed. Femto or nano molar concentrations of a material can be placed within the high reflectivity integrating cavity. At least the interior surface of the high reflectivity integrating cavity can comprise a coating that, at a designated wavelength of electromagnetic radiation, is transparent and non-absorbing to such designated wavelengths of electromagnetic radiation. In addition to the isotropic field induced by the interior surface of the high reflectivity integrating cavity, the high reflectivity of the interior surface of the high reflectivity integrating cavity leads to very large effective optical path lengths within the interior of the high reflectivity integrating cavity, thereby amplifying the luminescent emissions produced by the sample. |
FILED | Wednesday, January 20, 2016 |
APPL NO | 15/001238 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/645 (20130101) G01N 33/1826 (20130101) Original (OR) Class G01N 2021/6469 (20130101) G01N 2201/065 (20130101) G01N 2201/0697 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927604 | Uyar et al. |
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FUNDED BY |
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APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
INVENTOR(S) | M. Umit Uyar (New York, New York); Stephen Gundry (New York, New York) |
ABSTRACT | A method for tracking three-dimensional movement of an object and focusing thereon is provided. Software repeatedly detects three-dimensional locations of one or more objects and image quality by sampling images at many parameter settings as the objects move in three-dimensional environment. The images are ranked occurring to a fitness score and parameter settings for subsequent images to established using a biologically-inspired algorithm. |
FILED | Monday, September 14, 2015 |
APPL NO | 14/853460 |
ART UNIT | 2488 — Recording and Compression |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/241 (20130101) Original (OR) Class G02B 21/365 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00127 (20130101) G06K 2009/3291 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927616 | Hsu et al. |
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FUNDED BY |
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APPLICANT(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Chicago, Illinois); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Chia Wei Hsu (Cambridge, Massachusetts); Wenjun Qiu (Chicago, Illinois); Bo Zhen (Cambridge, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | Transparent displays enable many useful applications, including heads-up displays for cars and aircraft as well as displays on eyeglasses and glass windows. Unfortunately, transparent displays made of organic light-emitting diodes are typically expensive and opaque. Heads-up displays often require fixed light sources and have limited viewing angles. And transparent displays that use frequency conversion are typically energy inefficient. Conversely, the present transparent displays operate by scattering visible light from resonant nanoparticles with narrowband scattering cross sections and small absorption cross sections. More specifically, projecting an image onto a transparent screen doped with nanoparticles that selectively scatter light at the image wavelength(s) yields an image on the screen visible to an observer. Because the nanoparticles scatter light at only certain wavelengths, the screen is practically transparent under ambient light. Exemplary transparent scattering displays can be simple, inexpensive, scalable to large sizes, viewable over wide angular ranges, energy efficient, and transparent simultaneously. |
FILED | Tuesday, August 16, 2016 |
APPL NO | 15/237800 |
ART UNIT | 2875 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/0242 (20130101) G02B 5/0278 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 2027/0112 (20130101) G02B 2027/0145 (20130101) G02B 2027/0147 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927706 | Nealey et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Paul Franklin Nealey (Chicago, Illinois); Tzu-Hsuan Chang (Madison, Wisconsin); Shisheng Xiong (Darien, Illinois); Zhenqiang Ma (Middleton, Wisconsin); Michael Scott Arnold (Middleton, Wisconsin); Robert Jacobberger (Madison, Wisconsin) |
ABSTRACT | Provided herein are methods of directed self-assembly (DSA) on atomic layer chemical patterns and related compositions. The atomic layer chemical patterns may be formed from two-dimensional materials such as graphene. The atomic layer chemical patterns provide high resolution, low defect directed self-assembly. For example, DSA on a graphene pattern can be used achieve ten times the resolution of DSA that is achievable on a three-dimensional pattern such as a polymer brush. Assembly of block copolymers on the atomic layer chemical patterns may also facilitate subsequent etch, as the atomic layer chemical patterns are easier to etch than conventional pattern materials. |
FILED | Wednesday, July 20, 2016 |
APPL NO | 15/215016 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 153/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/0227 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/002 (20130101) G03F 7/165 (20130101) Original (OR) Class G03F 7/168 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32009 (20130101) H01J 2237/334 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02527 (20130101) H01L 21/02568 (20130101) H01L 21/3081 (20130101) H01L 21/3086 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927940 | Miller et al. |
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FUNDED BY |
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APPLICANT(S) | Earl Keith Miller (Cambridge, Massachusetts); Timothy Joseph Buschman (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Earl Keith Miller (Cambridge, Massachusetts); Timothy Joseph Buschman (Cambridge, Massachusetts) |
ABSTRACT | A method of displaying information includes presenting representations of information in a manner accounting for independent cognitive capacities corresponding to a subject's left and right halves of visual space. Weightings of importance may be assigned to the information and used to display the representations in the left half or the right half of the visual space with zero or few other representations. Presenting the representations can also include inspecting content of the information and determining a position on a display to present the content as a function of the information previously, currently, or in the future displayed on the display. In a display system, a presentation unit is configured to present, e.g. generate, representations of information in a manner accounting for the independent cognitive capacities, and a display unit is configured to display the representations. Displaying information can include arranging physical objects in locations of a subject's expected visual space. |
FILED | Friday, June 01, 2012 |
APPL NO | 13/486762 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Electric Digital Data Processing G06F 3/048 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928150 | Lin et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Hai Lin (Stanford, California); Subhasish Mitra (Palo Alto, California) |
ABSTRACT | A method of operating a test device for a logic-based processing device includes the steps of providing an original set of test instructions, generating one or more Quick Error Detection (QED) test programs, and causing the one or more QED test programs to be executed on the logic-based processing device. Each one of the QED test programs includes the original test program with additional instructions inserted at strategic locations within the original set, wherein the additional instructions and the strategic locations vary between each of the QED test programs. |
FILED | Monday, June 30, 2014 |
APPL NO | 14/318976 |
ART UNIT | 2851 — Printing/Measuring and Testing |
CURRENT CPC | Electric Digital Data Processing G06F 11/263 (20130101) G06F 11/2236 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928278 | Welinder et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Peter Welinder (San Diego, California); Pietro Perona (Altadena, California) |
ABSTRACT | Systems and methods for distributed data annotation in accordance embodiments of the invention are disclosed. In one embodiment of the invention, a distributed data annotation server system includes a storage device configured to store source data, one or more annotators, annotation tasks and a processor, wherein a distributed data annotation application configures the processor to receive source data including one or more pieces of source data, select one or more annotators, create one or more annotation tasks for the selected annotators and source data, request one or more annotations for the source data using the annotation tasks, receive annotations, determine source data metadata for at least one piece of source data using the received annotations, generate annotator metadata for at least one annotator using the received annotations and the source data, and estimate the ground truth for the source data using the source data metadata and the annotator metadata. |
FILED | Thursday, March 06, 2014 |
APPL NO | 14/198873 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 17/301 (20130101) G06F 17/30011 (20130101) G06F 17/30525 (20130101) Original (OR) Class G06F 17/30864 (20130101) G06F 17/30867 (20130101) G06F 17/30997 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/101 (20130101) G06Q 50/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928405 | De la Torre et al. |
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FUNDED BY |
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APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Fernando De la Torre (Pittsburgh, Pennsylvania); Xuehan Xiong (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to a system for detecting and tracking facial features in images and can be used in conjunction with a camera. Given a camera, the system will detect facial landmarks in images. The present invention includes software for real time, accurate facial feature detection and tracking in unconstrained images and videos. The present invention is better, more robust and faster than existing approaches and can be implemented very efficiently allowing real-time processing, even on low-power devices, such as mobile phones. |
FILED | Friday, May 27, 2016 |
APPL NO | 15/166317 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00281 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 2207/10016 (20130101) G06T 2207/20081 (20130101) G06T 2207/30201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09928406 | Bhanu et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Bir Bhanu (Riverside, California); Le An (Riverside, California); Ninad Thakoor (Riverside, California) |
ABSTRACT | A new image-based representation and an associated reference image is disclosed called the emotion avatar image (EAI), and the avatar reference, respectively, which leverages the out-of-plane head rotation. The method is not only robust to outliers but also provides a method to aggregate dynamic information from expressions with various lengths. The approach to facial expression analysis can consist of the following steps: 1) face detection; 2) face registration of video frames with the avatar reference to form the EAI representation; 3) computation of features from EAI using both local binary patterns and local phase quantization; and 4) the classification of the feature as one of the emotion type by using a linear support vector machine classifier. |
FILED | Tuesday, October 01, 2013 |
APPL NO | 14/042873 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00241 (20130101) G06K 9/00281 (20130101) G06K 9/00288 (20130101) Original (OR) Class G06K 9/00315 (20130101) G06K 9/00785 (20130101) G06K 9/6206 (20130101) G06K 9/6212 (20130101) G06K 2009/4666 (20130101) G06K 2209/23 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929725 | Jariwala et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Deep M. Jariwala (Evanston, Illinois); Vinod K. Sangwan (Syracuse, New York); Weichao Xu (Minneapolis, Minnesota); Hyungil Kim (Woodbury, Minnesota); Tobin J. Marks (Evanston, Illinois); Mark C. Hersam (Wilmette, Illinois) |
ABSTRACT | Van der Waals heterojunctions are extended to semiconducting p-type single-walled carbon nanotube (s-SWCNT) and n-type film that can be solution-processed with high spatial uniformity at the wafer scale. The resulting large-area, low-voltage p-n heterojunctions can exhibit anti-ambipolar transfer characteristics with high on/off ratios. The charge transport can be efficiently utilized in analog circuits such as frequency doublers and keying circuits that are widely used, for example, in telecommunication and wireless data transmission technologies. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/981245 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0017 (20130101) H01L 51/0048 (20130101) H01L 51/105 (20130101) H01L 51/0562 (20130101) H01L 2251/303 (20130101) Pulse Technique H03K 7/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09930105 | Reich et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Joshua Reich (New York, New York); Oren Laadan (New York, New York); Vishal Misra (New York, New York); Eliahu Brosh (New York, New York); Jason Nieh (New York, New York); Daniel Stuart Rubenstein (New York, New York); Alexander Sherman (New York, New York) |
ABSTRACT | Methods for distributing and providing access to stored content from remote storage comprising: receiving a first request to access a first portion of stored content from a requestor, wherein the first request is in a file system request format; creating a placeholder for the stored content so that the placeholder has at least one parameter identical to the stored content and the placeholder can hold the first portion of the stored content and at least a second portion of the stored content; requesting the first portion of the stored content from remote storage; receiving the first portion of the stored content from the remote storage; storing the first portion of the stored content in the placeholder; and before the second portion of the stored content has been stored in the placeholder, providing the first portion of the stored content to the requestor using a file system response format. |
FILED | Friday, February 17, 2017 |
APPL NO | 15/435629 |
ART UNIT | 2441 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 21/632 (20130101) H04N 21/4334 (20130101) H04N 21/8456 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09930777 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Alan T. Johnson (Philadelphia, Pennsylvania); Rajatesh R. Gudibande (Philadelphia, Pennsylvania); Zhengqing John Qi (Albany, New York) |
ABSTRACT | The present invention provides methods for fabricating graphene workpieces. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention. |
FILED | Thursday, April 23, 2015 |
APPL NO | 15/305167 |
ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) Original (OR) Class H05K 1/0306 (20130101) H05K 3/06 (20130101) H05K 3/20 (20130101) H05K 3/125 (20130101) H05K 3/1216 (20130101) H05K 3/1275 (20130101) H05K 2201/0323 (20130101) H05K 2203/1338 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 09924706 | Little et al. |
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FUNDED BY |
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APPLICANT(S) | Mississippi State University (Starkville, Mississippi) |
ASSIGNEE(S) | Mississippi State University (Mississippi State, Mississippi) |
INVENTOR(S) | Nathan S. Little (Starkville, Mississippi); John J. Riggins (Starkville, Mississippi); Tor P Schultz (Starkville, Mississippi) |
ABSTRACT | The present invention includes a new type of bait for wood-targeting pest baiting systems and methods of obtaining the bait. Certain embodiments of the present invention include a blue-stained wood either treated with a solution that includes blue-stain fungi or wood naturally infected with blue-stain fungi. Additional embodiments of the present invention include a blue-stained solution that may be applied to a wood substrate or to a non-wood bait matrix. |
FILED | Monday, May 13, 2013 |
APPL NO | 13/893051 |
ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/02 (20130101) A01M 1/2011 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926213 | Vanotti et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Matias B. Vanotti (Florence, South Carolina); Ariel A. Szogi (Florence, South Carolina); Patrick J. Dube (Florence, South Carolina) |
ABSTRACT | A system and method for capture of ammonia and phosphorus from an ammonia and phosphorus containing liquid effluent. The invention allows for the precipitation of phosphorus from said liquid effluent that has been under low aeration and has a pH of greater than about pH 9. |
FILED | Wednesday, June 01, 2016 |
APPL NO | 15/170129 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 19/0031 (20130101) B01D 21/01 (20130101) B01D 53/22 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/20 (20130101) C02F 1/44 (20130101) C02F 1/66 (20130101) C02F 1/5236 (20130101) Original (OR) Class C02F 1/5254 (20130101) C02F 9/00 (20130101) C02F 11/04 (20130101) C02F 2101/16 (20130101) C02F 2101/105 (20130101) C02F 2103/20 (20130101) C02F 2209/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926539 | Pan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Zhiqiang Pan (Oxford, Mississippi); Scott Baerson (Oxford, Mississippi) |
ABSTRACT | Two novel cytochrome P450 genes are isolated from sorghum, each gene encoding a protein having pentadecatrienyl resorcinol hydroxylase activity. Expression vectors containing these sequences are made and used to elevate levels of pentadecatrienyl resorcinol hydroxylase in transgenic cells and organisms. |
FILED | Tuesday, January 26, 2016 |
APPL NO | 15/006221 |
ART UNIT | 1663 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) C12N 9/0073 (20130101) Original (OR) Class C12N 15/82 (20130101) C12N 2820/002 (20130101) C12N 2820/007 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/22 (20130101) C12P 7/66 (20130101) Enzymes C12Y 114/13 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926581 | Obendorf et al. |
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FUNDED BY |
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APPLICANT(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
INVENTOR(S) | Ralph L. Obendorf (Ithaca, New York); Takashi Ueda (Fort Myers, Florida) |
ABSTRACT | The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analog, an insulin mediator homolog, or an insulin mediator inhibitor is also described. The method includes providing a fagopyritol synthase, providing a substrate comprising a galactosyl donor and a galactosyl acceptor, and combining the fagopyritol synthase with the substrate under conditions effective produce a fagopyritol, an insulin mediator, an insulin mediator analog, an insulin mediator homolog, or an insulin mediator inhibitor. |
FILED | Monday, June 27, 2016 |
APPL NO | 15/194232 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1051 (20130101) C12N 15/8245 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/26 (20130101) C12P 19/46 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926608 | Khatib |
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FUNDED BY |
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APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Hasan Khatib (Fitchburg, Wisconsin) |
ABSTRACT | Oligonucleic acid molecules comprising a SNP site at a position corresponding to position 7480 of the bovine signal transducer and activator of transcription (STAT5A) coding sequence (SEQ ID NO: 1). Also disclosed are an array or a kit comprising the same, a method for detecting the SNPs, a method for progeny testing of mammals, a method for increasing human and non-human mammal pregnancy rate in natural and artificial reproduction processes. Further provided are cattle breeding methods for improved milk production traits. |
FILED | Friday, December 04, 2015 |
APPL NO | 14/958951 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2227/101 (20130101) Veterinary Instruments, Implements, Tools, or Methods A61D 19/02 (20130101) A61D 19/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6888 (20130101) Original (OR) Class C12Q 2600/124 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927364 | Chao et al. |
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FUNDED BY |
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APPLICANT(S) | Kuanglin Chao (Ellicott, Maryland); Moon S. Kim (Silver Spring, Maryland); Jianwei Qin (Ellicott City, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia); University of Maryland (College Park, Maryland) |
INVENTOR(S) | Kuanglin Chao (Ellicott, Maryland); Moon S. Kim (Silver Spring, Maryland); Jianwei Qin (Ellicott City, Maryland) |
ABSTRACT | A line-scan laser is directed to a sample so that a Raman-shifted light signal is emitted from the sample. An imaging spectrograph and associated camera and processor acquires the Raman-shifted light signal and processes the signal to thereby identify the composition of the sample. |
FILED | Friday, November 01, 2013 |
APPL NO | 14/069827 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 09924867 | Abramoff et al. |
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FUNDED BY |
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APPLICANT(S) | Michael D. Abramoff (University Heights, Iowa); Melndert Niemeijer (Iowa City, Iowa); Xiayu Xu (Iowa City, Iowa); Milan Sonka (Coralville, Iowa); Joseph M. Reinhardt (Iowa City, Iowa) |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); The United States of America, as represented by the Secretary of the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Michael D. Abramoff (University Heights, Iowa); Melndert Niemeijer (Iowa City, Iowa); Xiayu Xu (Iowa City, Iowa); Milan Sonka (Coralville, Iowa); Joseph M. Reinhardt (Iowa City, Iowa) |
ABSTRACT | The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct. |
FILED | Friday, January 20, 2012 |
APPL NO | 13/355386 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) Original (OR) Class A61B 3/0016 (20130101) A61B 3/0058 (20130101) A61B 3/1225 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09925308 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
INVENTOR(S) | James Chang (Stanford, California); Hung Pham (Milpitas, California); Colin Woon (Chicago, Illinois); Simon Farnebo (Palo Alto, California); Anais Legrand (Palo Alto, California) |
ABSTRACT | The invention provides an injectable composition and method for the minimally invasive, in-situ repair and regeneration of an injured ligament or tendon in a mammalian subject. The composition is also useful for the delivery of growth factors, therapeutic agents and cells into the area of tendon or ligament injury. |
FILED | Tuesday, September 15, 2015 |
APPL NO | 14/855034 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/12 (20130101) A61K 35/16 (20130101) A61K 38/28 (20130101) A61K 38/28 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/50 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/386 (20130101) A61L 27/3633 (20130101) A61L 27/3662 (20130101) A61L 27/3687 (20130101) A61L 27/3804 (20130101) A61L 27/3834 (20130101) A61L 2300/45 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) A61L 2300/402 (20130101) A61L 2300/406 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2430/10 (20130101) A61L 2430/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926360 | Burrows et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States of America as represented by the Deparment of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Gregory G. Burrows (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon) |
ABSTRACT | The present invention provides, in particular embodiments, for modified recombinant T cell receptor (TCR) ligands (RTLs) comprising a MHC class I or MHC class II component. The modified RTLs have redesigned surface features that preclude or reduce aggregation, wherein the modified molecules retain the ability to bind Ag-peptides, target antigen-specific T cells, inhibit T cell proliferation in an Ag-specific manner and have utility to treat, inter alia, autoimmune disease and other conditions mediated by antigen-specific T cells in vivo. |
FILED | Thursday, December 17, 2015 |
APPL NO | 14/973033 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/86 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926565 | Chu |
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FUNDED BY |
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APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Cong-Qiu Chu (Lake Oswego, Oregon) |
ABSTRACT | A recombinant nucleic acid comprising an aptamer that binds CD4 and an RNAi sequence that silences the expression of RORγ2 is described herein. Pharmaceutical compositions comprising the recombinant nucleic acid, particularly topical compositions are also described. Methods of treating inflammatory disease using the pharmaceutical composition are also described. |
FILED | Tuesday, September 22, 2015 |
APPL NO | 14/862065 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 09925209 | DeAngelis |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma) |
INVENTOR(S) | Paul L. DeAngelis (Edmond, Oklahoma) |
ABSTRACT | Compositions containing conjugates of heparosan polymer with at least one drug are disclosed, along with methods of production and use thereof. |
FILED | Friday, November 07, 2014 |
APPL NO | 14/536003 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Original (OR) Class A61K 38/21 (20130101) A61K 38/22 (20130101) A61K 38/27 (20130101) A61K 38/28 (20130101) A61K 38/50 (20130101) A61K 38/193 (20130101) A61K 39/395 (20130101) A61K 47/61 (20170801) A61K 2039/505 (20130101) Enzymes C12Y 305/01001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926351 | Schellenberger et al. |
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FUNDED BY |
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APPLICANT(S) | Amunix Operating Inc. (Mountain View, California) |
ASSIGNEE(S) | Amunix Operating Inc. (Mountain View, California) |
INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Los Altos Hills, California); Chia-wei Wang (Santa Clara, California); Benjamin Spink (San Carlos, California); Willem P. Stemmer (Los Gatos, California); Nathan Geething (Natick, Massachusetts); Wayne To (Fremont, California); Jeffrey L. Cleland (San Carlos, California) |
ABSTRACT | The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions. |
FILED | Friday, May 13, 2016 |
APPL NO | 15/154223 |
ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/001 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/61 (20130101) C07K 14/545 (20130101) C07K 14/605 (20130101) C07K 14/745 (20130101) C07K 2319/31 (20130101) C07K 2319/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/644 (20130101) C12N 9/6437 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926381 | Welt et al. |
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FUNDED BY |
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APPLICANT(S) | Welt Bio-Molecular Pharmaceutlical, LLC (Armonk, New York) |
ASSIGNEE(S) | WELT BIO-MOLECULAR PHARMACEUTICAL, LLC. (Armonk, New York) |
INVENTOR(S) | Sydney Welt (Armonk, New York); David Kostyal (Akron, Ohio); Rachel S Welt (Armonk, New York); Virginia Raymond (Armonk, New York); Jonathan A Welt (Armonk, New York) |
ABSTRACT | The present invention relates to monoclonal antibodies targeting the membrane bound IgM (mIgM) of the B-cell receptor complex found in B-cell lymphomas and leukemias. Monoclonal antibodies designated mAb4-2b, mAb1-1, mAb2-2b and mAb3-2b were produced by hybridoma cell lines (ATCC deposit no. PTA-121716), (ATCC deposit no. PTA-121719), (ATCC deposit no. PTA-121717), and (ATCC deposit no. PTA-121718), respectively. Another aspect of the present invention is the use of anti-B-Cell mIgM antibodies in the treatment of B-cell malignancies, including B-cell lymphomas and leukemias. |
FILED | Monday, December 01, 2014 |
APPL NO | 15/101658 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 16/4283 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/34 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/77 (20130101) C07K 2317/565 (20130101) C07K 2317/732 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/163 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927217 | Carlson et al. |
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FUNDED BY |
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APPLICANT(S) | Valley Tech Systems (Reno, Nevada) |
ASSIGNEE(S) | Valley Tech Systems, Inc. (Reno, Nevada) |
INVENTOR(S) | Russell Carlson (Reno, Nevada); Dustin Barr (Reno, Nevada); Allen Yan (Reno, Nevada) |
ABSTRACT | An attitude control system for a guided missile includes a gas generator, an accumulator coupled to the gas generator, and a valve positioned between the gas generator and the accumulator. The gas generator contains propellant that burns to provide hot gas to pressurize the accumulator. The valve is opened to recharge the accumulator with hot gas and closed when it is full. A vent valve can be included to extinguish the propellant in the gas generator. The accumulator can be coupled to thrusters that use the stored hot gas to adjust the attitude of the guided missile. |
FILED | Tuesday, September 08, 2015 |
APPL NO | 14/847820 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/661 (20130101) Original (OR) Class F42B 15/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 09927287 | Rhoads et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Jeffrey Frederick Rhoads (West Lafayette, Indiana); George Tsu-Chih Chiu (West Lafayette, Indiana); Nikhil Bajaj (West Lafayette, Indiana); Andrew Burke Sabater (Claremont, California) |
ABSTRACT | A device and method for sensing including a sensor having a functional surface layer located to interact with a material to be sensed, the sensor having an output that produces a signal responsive one or more of inertia, stiffness, acceleration, pressure, radiation, chemical compounds, and biological compounds; and further including electronics including: an input coupled to the sensor to receive a first signal therefrom; and a non-linearity provider that applies one or more non-linear operations to the input signal to generate a non-linear second signal. |
FILED | Thursday, December 17, 2015 |
APPL NO | 14/973262 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 13/00 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/00 (20130101) G01P 15/097 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927440 | Hellinga et al. |
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FUNDED BY |
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APPLICANT(S) | Homme W. Hellinga (Durham, North Carolina); Malin J. Allert (Raleigh, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Homme W. Hellinga (Durham, North Carolina); Malin J. Allert (Raleigh, North Carolina) |
ABSTRACT | Methods of optimizing mRNA sequences for expression in host cells are provided. Methods of determining the stability of a protein are also provided. Methods of determining the affinity of a ligand for a protein are also provided. |
FILED | Wednesday, November 24, 2010 |
APPL NO | 12/954317 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6803 (20130101) Original (OR) Class Electric Digital Data Processing G06F 19/16 (20130101) G06F 19/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929365 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); The University of Southern California (Los Angeles, California) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Michael Slootsky (Ann Arbor, Michigan); Mark E. Thompson (Anaheim Hills, California) |
ABSTRACT | Arrangements and techniques for providing organic emissive layers are provided, in which the emissive layer includes a first dopant having a dissociative energy level. A second dopant in the emissive layer provides a solid state sink energy level, to which doubly excited excitons and/or polarons may transition instead of to the dissociative energy level, thereby decreasing the undesirable effects of transitions to the dissociative energy level. |
FILED | Thursday, May 28, 2015 |
APPL NO | 14/724238 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1011 (20130101) C09K 2211/1088 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/5016 (20130101) H01L 51/5028 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 09925510 | Jacobson et al. |
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FUNDED BY |
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APPLICANT(S) | Gen9, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | Gen9, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Joseph Jacobson (Newton, Massachusetts); Larry Li-Yang Chu (Brighton, Massachusetts) |
ABSTRACT | Methods and apparatus relate to the synthesis of high fidelity polynucleotides and to the reduction of sequence errors generated during synthesis of nucleic acids on a solid support. Specifically, design of support-bound template oligonucleotides is disclosed. Assembly methods include cycles of annealing, stringent wash and extension of polynucleotides comprising a sequence region complementary to immobilized template oligonucleotides. The error free synthetic nucleic acids generated therefrom can be used for a variety of applications, including synthesis of biofuels and value-added pharmaceutical products. |
FILED | Friday, November 20, 2015 |
APPL NO | 14/947655 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00608 (20130101) B01J 2219/00722 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1031 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6811 (20130101) C12Q 1/6837 (20130101) C12Q 2525/301 (20130101) C12Q 2565/525 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929725 | Jariwala et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Deep M. Jariwala (Evanston, Illinois); Vinod K. Sangwan (Syracuse, New York); Weichao Xu (Minneapolis, Minnesota); Hyungil Kim (Woodbury, Minnesota); Tobin J. Marks (Evanston, Illinois); Mark C. Hersam (Wilmette, Illinois) |
ABSTRACT | Van der Waals heterojunctions are extended to semiconducting p-type single-walled carbon nanotube (s-SWCNT) and n-type film that can be solution-processed with high spatial uniformity at the wafer scale. The resulting large-area, low-voltage p-n heterojunctions can exhibit anti-ambipolar transfer characteristics with high on/off ratios. The charge transport can be efficiently utilized in analog circuits such as frequency doublers and keying circuits that are widely used, for example, in telecommunication and wireless data transmission technologies. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/981245 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0017 (20130101) H01L 51/0048 (20130101) H01L 51/105 (20130101) H01L 51/0562 (20130101) H01L 2251/303 (20130101) Pulse Technique H03K 7/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 09926408 | Avakian et al. |
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FUNDED BY |
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APPLICANT(S) | PolyOne Corporation (Avon Lake, Ohio) |
ASSIGNEE(S) | PolyOne Corporation (Avon Lake, Ohio) |
INVENTOR(S) | Roger W. Avakian (Solon, Ohio); Ling Hu (Westlake, Ohio) |
ABSTRACT | Reactive extrusion can be used in a continuous, solvent-less preparation of imide oligomers involving two competing reactions among three ingredients, the first reaction between a dianhydride and a diamine and the second reaction between an endcap and the same diamine. The imide oligomer can form a composite via conventional production methods or via formation of a film from imide oligomer re-melted in an extruder before being impregnated into tape or fabric. |
FILED | Wednesday, September 24, 2014 |
APPL NO | 15/024833 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0004 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/105 (20130101) C08G 73/1014 (20130101) C08G 73/1028 (20130101) C08G 73/1067 (20130101) Original (OR) Class C08G 73/1071 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/24 (20130101) C08J 5/042 (20130101) C08J 2379/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/06 (20130101) C08K 7/06 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 179/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09926885 | Gallagher et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Edward J. Gallagher (West Hartford, Connecticut); Byron R. Monzon (Cromwell, Connecticut) |
ABSTRACT | A gas turbine engine includes a bypass flow passage that has an inlet and defines a bypass ratio in a range of approximately 8.5 to 13.5. A fan is arranged within the bypass flow passage. A first turbine is a 5-stage turbine and is coupled with a first shaft, which is coupled with the fan. A first compressor is coupled with the first shaft and is a 3-stage compressor. A second turbine is coupled with a second shaft and is a 2-stage turbine. The fan includes a row of fan blades that extend from a hub. The row includes a number (N) of the fan blades, a solidity value (R) at tips of the fab blades, and a ratio of N/R that is from 14 to 16. |
FILED | Wednesday, September 20, 2017 |
APPL NO | 15/709540 |
ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/14 (20130101) Jet-propulsion Plants F02K 1/06 (20130101) F02K 3/06 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/327 (20130101) F05D 2260/4031 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 09927572 | Kurczveil et al. |
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FUNDED BY |
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APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
INVENTOR(S) | Geza Kurczveil (Palo Alto, California); Di Liang (Santa Barbara, California); Zhihong Huang (Palo Alto, California); Raymond G Beausoleil (Seattle, Washington) |
ABSTRACT | Examples include hybrid silicon photonic device structures. Some examples include a method of integrating a photodetector with a photonic device on a silicon wafer to make a hybrid silicon photonic device structure. A dielectric layer is established on the silicon wafer. A pit is formed in a portion of the dielectric layer and the silicon wafer, wherein a bottom of the pit is silicon. A germanium layer is grown in the pit such that a top of the germanium layer is lower than a top of the silicon wafer. The germanium layer comprises the photodetector. A photonic device material that comprises the photonic device is bonded to the silicon wafer without planarization of the silicon wafer. |
FILED | Wednesday, January 04, 2017 |
APPL NO | 15/397903 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12002 (20130101) G02B 6/12004 (20130101) Original (OR) Class G02B 2006/12061 (20130101) G02B 2006/12121 (20130101) G02B 2006/12123 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09930325 | Ainspan et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Herschel A Ainspan (New Hempstead, New York); Seongwon Kim (Old Tappan, New Jersey); Franco Stellari (Waldwick, New Jersey); Alan J. Weger (Mohegan Lake, New York) |
ABSTRACT | Methods for testing the resolution of an imaging device include forming a plurality of semiconductor devices having proximal light emitting regions, such that the light emitting regions are grouped into distinct shapes separated by a distance governed by a target resolution size. The semiconductor devices are activated by providing an input signal. Light emissions from one or more of the activated semiconductor devices are suppressed by providing one or more select signals. |
FILED | Thursday, November 12, 2015 |
APPL NO | 14/939788 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) G01J 11/00 (20130101) G01J 2001/4238 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/26 (20130101) Pulse Technique H03K 19/14 (20130101) H03K 19/094 (20130101) Pictorial Communication, e.g Television H04N 17/002 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 09927347 | LoPresti et al. |
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FUNDED BY |
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APPLICANT(S) | State of California Department of Transportation (Sacramento, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Thomas LoPresti (Placerville, California); Joseph F. Peterson (Marysville, California) |
ABSTRACT | Pneumatic ram road surface coefficient of friction measuring device is a stationary device that measures the coefficient of friction of a particular spot on a road surface using a known and precise amount of resistance force supplied from a pneumatic ram and a calibration valve. Pneumatic ram road surface coefficient of friction measuring device comprises a testing tire and wheel mounted to a carriage plate that is slideably attached to a framework that pivots around the front end of the framework and is supported by a jack mechanism at the rear end. Pneumatic ram provides resistance to the sliding action of the carriage plate that may be varied using the calibration valve. Pneumatic ram road surface coefficient of friction measuring device further comprises a sliding gauge indicator and coefficient of friction graduations that provide the coefficient of friction reading. |
FILED | Sunday, May 01, 2016 |
APPL NO | 15/143591 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 19/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
US 09926596 | Esfandyarpour et al. |
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FUNDED BY |
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APPLICANT(S) | Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California) |
ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Kosar Baghbani Parizi (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Eric S. Nordman (Palo Alto, California); Richard T. Reel (Hayward, California); Susanne Baumhueter (Redwood City, California); Cheryl Heiner (La Honda, California); Frank Lee (Irvine, California) |
ABSTRACT | The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices. |
FILED | Tuesday, May 29, 2012 |
APPL NO | 14/119859 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2527/119 (20130101) C12Q 2527/119 (20130101) C12Q 2549/126 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
US 09929300 | Stan et al. |
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FUNDED BY |
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APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
INVENTOR(S) | Mark Stan (Albuquerque, New Mexico); Chelsea Mackos (Albuquerque, New Mexico); Jeff Steinfeldt (Rio Rancho, New Mexico) |
ABSTRACT | A solar cell including a sequence of layers of semiconductor material forming a solar cell; a metal contact layer over said sequence of layers; a permanent supporting substrate composed of a carbon fiber reinforced polymer utilizing a conductive polyimide binding resin disposed directly over said metal contact layer and permanently bonding thereto. |
FILED | Monday, February 27, 2017 |
APPL NO | 15/442951 |
ART UNIT | 2829 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0203 (20130101) H01L 31/0725 (20130101) Original (OR) Class H01L 31/0735 (20130101) H01L 31/022441 (20130101) H01L 31/035272 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 09927347 | LoPresti et al. |
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FUNDED BY |
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APPLICANT(S) | State of California Department of Transportation (Sacramento, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Thomas LoPresti (Placerville, California); Joseph F. Peterson (Marysville, California) |
ABSTRACT | Pneumatic ram road surface coefficient of friction measuring device is a stationary device that measures the coefficient of friction of a particular spot on a road surface using a known and precise amount of resistance force supplied from a pneumatic ram and a calibration valve. Pneumatic ram road surface coefficient of friction measuring device comprises a testing tire and wheel mounted to a carriage plate that is slideably attached to a framework that pivots around the front end of the framework and is supported by a jack mechanism at the rear end. Pneumatic ram provides resistance to the sliding action of the carriage plate that may be varied using the calibration valve. Pneumatic ram road surface coefficient of friction measuring device further comprises a sliding gauge indicator and coefficient of friction graduations that provide the coefficient of friction reading. |
FILED | Sunday, May 01, 2016 |
APPL NO | 15/143591 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 19/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 09926849 | Frost et al. |
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FUNDED BY |
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APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morristown, New Jersey) |
ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
INVENTOR(S) | Cristopher Frost (Scottsdale, Arizona); Mariee Hayden (Wisconsin Rapids, Wisconsin); Michael Stephen Crestin (Chandler, Arizona); James Laffan (Phoenix, Arizona); Mingfong Hwang (Phoenix, Arizona); Doug Hollingshead (Phoenix, Arizona); Marc Schmittenberg (Phoenix, Arizona) |
ABSTRACT | An accessory gear box for a gas turbine engine having a drive shaft with a rotational axis and a tower shaft coupled to the drive shaft is provided. The accessory gear box includes a first plurality of gears arranged, which extend along a first axis substantially parallel to the rotational axis of the drive shaft. The accessory gear box includes a second plurality of gears, which extend along a second axis. The accessory gear box includes a first shaft, with one of the first plurality of gears coupled to the first shaft, and one of the second plurality of gears coupled to a second shaft. The one of the second plurality of gears coupled to the first shaft includes a first engagement surface and a second engagement surface, and the second engagement surface is coupled to another one of the second plurality of gears to drive the second shaft. |
FILED | Wednesday, August 26, 2015 |
APPL NO | 14/836484 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/32 (20130101) Original (OR) Class F02C 7/36 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/313 (20130101) F05D 2260/53 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/671 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09927337 | Kombolias |
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FUNDED BY |
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APPLICANT(S) | U.S.A. as represented by Government Publishing Off (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Government Publishing Office (Washington, District of Columbia) |
INVENTOR(S) | Mary Kombolias (Washington, District of Columbia) |
ABSTRACT | Embodiments of the invention include systems and methods for determining adhesive strength of a sample label. For example, the present invention relates to a novel approach for examining the resistance to peel force required to remove a pressure sensitive adhesive (PSA) label from its intended substrate. This approach is encompassed by systems and methods which rely on the creation of one or any combination of at least four test strip types traced and cut from a label adhered to its intended substrate. The test strips may be oriented in at least three ways: along the machine direction of the label's face stock, along the cross direction of the label's face stock, and along an angle diagonal to the intersection of the machine and cross directions of the label's face stock, where the angle does not equal 0°, 90°, 180°, 270°, or 360°. The test strips may be peeled in reference to the position along the label and to and from which they extend. |
FILED | Tuesday, June 30, 2015 |
APPL NO | 14/755704 |
ART UNIT | 2854 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/08 (20130101) Original (OR) Class G01N 19/04 (20130101) G01N 2203/0091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929739 | Zanchi |
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FUNDED BY |
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APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Alfio Zanchi (Huntington Beach, California) |
ABSTRACT | A method of determining Integral Non-Linearity (INL) of an Analog-to-Digital Converter (ADC) is provided. The method includes providing an input signal to the ADC, phase-locking a clock signal of a clock of the ADC to the input signal, generating a plurality of samples at a sampled phase on the input signal for a plurality of sampled phases, applying averaging to the plurality of samples for each sampled phase to generate a reconstructed ADC output signal, and determining the INL of the ADC based on a comparison of the reconstructed ADC output signal to a theoretical ADC output signal. |
FILED | Monday, June 05, 2017 |
APPL NO | 15/613625 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/0612 (20130101) H03M 1/0663 (20130101) H03M 1/0863 (20130101) H03M 1/1019 (20130101) H03M 1/1033 (20130101) Original (OR) Class H03M 1/1235 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09929978 | Naaman |
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FUNDED BY |
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APPLICANT(S) | Ofer Naaman (Ellicott City, Maryland) |
ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
INVENTOR(S) | Ofer Naaman (Ellicott City, Maryland) |
ABSTRACT | A superconducting cross-bar switch system comprises a first input port coupled to a first output port through a first variable inductance coupling element, and a second output port through a third variable inductance coupling element, and a second input port coupled to the first output port through a second variable inductance coupling element, and the second output port through a fourth variable inductance coupling element. A switch controller controls the setting of the cross-bar switch between a Bar state and a Cross state by changing the variable inductance coupling elements between opposing inductance states. This allows for selective routing of signals between the first input port to the first output port and the second input port to the second output port in the Bar state, and the first input port to the second output port and the second input port to the first output port in the Cross state. |
FILED | Wednesday, October 07, 2015 |
APPL NO | 14/877515 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 49/15 (20130101) H04L 49/40 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, March 27, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180327.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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