FedInvent™ Patents
Patent Details for Tuesday, April 24, 2018
This page was updated on Monday, March 27, 2023 at 05:31 AM GMT
Department of Health and Human Services (HHS)
| US 09949480 | Turos et al. |
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| FUNDED BY |
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| APPLICANT(S) | Edward Turos (Wesley Chapel, Florida); Kevin D. Revell (Murray, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Edward Turos (Wesley Chapel, Florida); Kevin D. Revell (Murray, Kentucky) |
| ABSTRACT | The present invention provides N-alkylthio β-lactams and disulfide compounds (e.g., alkyl-coenzyme A asymmetric disulfides or aryl-alkyl disulfides), compositions containing such compounds, and methods of their use as anti-bacterial agents. |
| FILED | Wednesday, July 29, 2015 |
| APPL NO | 14/812799 |
| ART UNIT | 1673 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 41/12 (20130101) A01N 43/44 (20130101) Original (OR) Class A01N 57/16 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/105 (20130101) A61K 31/397 (20130101) A61K 31/7076 (20130101) Acyclic or Carbocyclic Compounds C07C 321/28 (20130101) Heterocyclic Compounds C07D 205/08 (20130101) C07D 213/71 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/16 (20130101) C07H 19/207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949634 | Buckland et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bioptigen, Inc. (Morrisville, North Carolina) |
| ASSIGNEE(S) | Bioptigen, Inc. (Morrisville, North Carolina) |
| INVENTOR(S) | Eric L. Buckland (Hickory, North Carolina); Andrew Murnan (Saratoga Springs, New York); Nestor O. Farmiga (Rochester, New York); Robert H. Hart (Cary, North Carolina); Christopher Saxer (Chapel Hill, North Carolina) |
| ABSTRACT | Optical coherence tomography (OCT) imaging systems are provided including a source of broadband optical radiation coupled to a sample arm of the OCT imaging system; a beam shaping optical assembly in the sample arm, the beam shaping optical assembly being configured to receive optical radiation from the source as a beam of optical radiation and to shape the spatial profile of the beam of optical radiation; a scan mirror assembly coupled to the beam shaping optical assembly; and objective lens assembly coupled to the beam shaping optical assembly. The beam shaping optical assembly includes a lens assembly configured to change a NA of the OCT system without changing a focus; to change a focus of the OCT system without changing a NA of the system; or to change both the NA and the focus of the OCT system responsive to a control input. |
| FILED | Wednesday, June 04, 2014 |
| APPL NO | 14/295664 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) Original (OR) Class A61B 3/1025 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02038 (20130101) G01B 9/02042 (20130101) G01B 9/02091 (20130101) Optical Elements, Systems, or Apparatus G02B 19/0014 (20130101) G02B 23/2407 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949659 | Armoundas |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Antonis Armoundas (Lincoln, Massachusetts) |
| ABSTRACT | A system and method for determining and controlling a cardiac condition of a subject are provided. In some aspects, the method includes acquiring ECG signals using one or more electrodes configured to sense a cardiac activity of a subject, and analyzing the ECG signals to delineate cardiac waveforms on a beat-to-beat basis. The method also includes identifying, in the delineated cardiac waveforms, characteristic points associated with different phases of cardiac activity, and for each delineated cardiac waveform, computing an ischemic index using the ECG signals corresponding to a ventricular depolarization period and a ventricular repolarization period, wherein the ventricular depolarization period and the ventricular repolarization period are defined by the identified characteristic points. The method further includes determining a cardiac condition of the subject using each computed ischemic index. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 14/671395 |
| ART UNIT | 3766 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/026 (20130101) A61B 5/042 (20130101) A61B 5/0456 (20130101) A61B 5/0464 (20130101) Original (OR) Class A61B 5/04085 (20130101) A61B 5/04525 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) A61M 2230/04 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36592 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949709 | Yi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Byong Yong Yi (Fulton, Maryland); Nilesh N. Mistry (Cary, North Carolina); Xinsheng Cedric Yu (Pasadena, Maryland); Giovanni Lasio (Bel Air, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Byong Yong Yi (Fulton, Maryland); Nilesh N. Mistry (Cary, North Carolina); Xinsheng Cedric Yu (Pasadena, Maryland); Giovanni Lasio (Bel Air, Maryland) |
| ABSTRACT | Techniques for suppression of motion artifacts in medical imaging include obtaining projections at different times within a time interval from a medical imaging system operating on a subject. A stationary projection is determined for a first subset of the projections in which a signal source and detector array of the imaging system are in a first configuration relative to the subject. An image of the subject based on the stationary projection is displayed. For any subset, the stationary projection is a minimum value for each pixel among the subset of projections if a signal passing through a moving object of interest inside the subject is expected to cause an increase in a pixel value. Alternatively, the stationary projection is a maximum value for each pixel among the subset of projections if the signal passing through the object of interest is expected to cause a decrease in a pixel value. |
| FILED | Tuesday, June 23, 2015 |
| APPL NO | 15/319604 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/42 (20130101) A61B 6/50 (20130101) A61B 6/461 (20130101) A61B 6/4085 (20130101) A61B 6/5264 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949722 | Mauldin, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | F. William Mauldin, Jr. (Charlottesville, Virginia); Shiying Wang (Charlottesville, Virginia); John A. Hossack (Charlottesville, Virginia); Alexander L. Klibanov (Charlottesville, Virginia) |
| ABSTRACT | An ultrasound system and method that can include: a receive beamformer configured to receive signals from a transducer; a processor coupled to the receive beamformer, the processor configured to: analyze echo data reflected from a region of interest, the echo data elicited by a transmitted pulse sequence; using the echo data, determine a central tendency of a signal magnitude from regions of adherent microbubbles over time within the region of interest; determine a time series of the signal magnitude; using the time series, determine an initial signal magnitude parameter; obtain a saturated signal parameter and a residual signal parameter using the time series; and determine a relative indication of information indicative of the residual signal magnitude versus the saturated signal magnitude. |
| FILED | Wednesday, December 03, 2014 |
| APPL NO | 14/559422 |
| ART UNIT | 3768 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) Original (OR) Class A61B 8/587 (20130101) A61B 8/0891 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 2207/10132 (20130101) G06T 2207/30104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949950 | Benoit et al. |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | Danielle Benoit (Rochester, New York); J. Edward Puzas (Pittsford, New York); Maureen Newman (Rochester, New York); Tzong-Jen Sheu (Rochester, New York) |
| ABSTRACT | The present invention provides compositions and methods for providing controllable local delivery of a therapeutic agent to promote bone formation. In certain embodiments, the invention is used as a treatment for a subject with osteoporosis, bone cancer or bone fracture. The invention provides a therapeutic agent that is tethered to a polymer to form a therapeutic-tethered macromer, where the therapeutic agent is controllably released from the conjugate by degradation of the tether. In certain embodiments, the therapeutic agent is an inhibitor of GSK3β. In certain embodiments, the composition of the invention is specifically targeted to a site in need of bone formation. |
| FILED | Monday, September 14, 2015 |
| APPL NO | 14/853772 |
| ART UNIT | 1676 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class A61K 47/48176 (20130101) A61K 47/48246 (20130101) A61K 47/48869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949965 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Taekyu Lee (Brentwood, Tennessee); Jason P. Burke (Houston, Texas); Edward T. Olejniczak (Nashville, Tennessee); Johannes Belmar (Nashville, Tennessee); Zhiguo Bian (Nashville, Tennessee); Stephen W. Fesik (Nashville, Tennessee) |
| ABSTRACT | The present invention provides for compounds that inhibit the activity of an anti-apoptotic Bcl-2 family member Myeloid cell leukemia-1 (Mcl-1) protein. The present invention also provides for pharmaceutical compositions as well as methods for using compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 14/885181 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/542 (20130101) A61K 31/554 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/5383 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 471/08 (20130101) C07D 498/06 (20130101) C07D 513/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949980 | Lambert et al. |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Paul F. Lambert (Madison, Wisconsin); Paul G. Ahlquist (Madison, Wisconsin); Dohun Pyeon (Greenwood Village, Colorado); Hao Shun Huang (Madison, Wisconsin) |
| ABSTRACT | A method of inhibiting HPV virus infection is disclosed. In one embodiment, the method involves exposing a papillomavirus to an effective amount of a compound selected from the group consisting of Compound 13, Compound 14, and analogs of Compounds 13 and 14. In another embodiment, the method involves administering an inhibitor selected from the group consisting of Compound 13, Compound 14, and analogs of Compounds 13 and 14 to a susceptible tissue or cell. |
| FILED | Tuesday, June 02, 2015 |
| APPL NO | 14/728028 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 9/0034 (20130101) A61K 31/53 (20130101) Original (OR) Class A61K 31/166 (20130101) A61K 31/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949995 | Bonomo et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleaveland, Ohio) |
| INVENTOR(S) | Robert Bonomo (Cleveland, Ohio); Fabio Prati (Modena MO, Italy); Emilia Caselli (Modena MO, Italy); Chiara Romagnoli (Modena MO, Italy) |
| ABSTRACT | A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one β-lactam antibiotic and at least one triazolylmethyl boronic acid. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257706 |
| ART UNIT | 1671 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) Original (OR) Class A61K 31/407 (20130101) A61K 31/546 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950007 | Self et al. |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | William T. Self (Oviedo, Florida); Ella Bossy-Wetzel (Winter Park, Florida); Sudipta Seal (Orlando, Florida); Janet Dowding (Winter Garden, Florida) |
| ABSTRACT | A method of treating a subject with elevated levels of peroxynitrite includes administering a therapeutically effective amount of cerium oxide nanoparticles to the subject, wherein the cerium oxide nanoparticles reduce the level of peroxynitrite in the subject. |
| FILED | Monday, June 08, 2015 |
| APPL NO | 14/733185 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950026 | Szeto |
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| APPLICANT(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL RESEARCH FOUNDATION, INC. (Ithaca, New York) |
| INVENTOR(S) | Hazel H. Szeto (New York, New York) |
| ABSTRACT | The invention provides a method for reducing oxidative damage in a mammal, a removed organ, or a cell in need thereof. The method comprises administering an effective amount of an aromatic cationic peptide. The aromatic cationic peptide has (a) at least one net positive charge; (b) a minimum of three amino acids; (c) a maximum of about twenty amino acids, (d) a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3 pm is the largest number that is less than or equal to r+1; (e) a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 3a or 2a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1; and (f) at least one tyrosine or tryptophan amino acid. |
| FILED | Tuesday, December 01, 2015 |
| APPL NO | 14/955412 |
| ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/07 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 38/10 (20130101) Peptides C07K 5/1019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950037 | Teague et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma); Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma); Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| INVENTOR(S) | Tracy Kent Teague (Tulsa, Oklahoma); Jonathan D. Wren (Norman, Oklahoma); Siva Kumar Gandhapudi (Oklahoma City, Oklahoma); Julie Harris Marino (Tulsa, Oklahoma); Chibing Tan (Broken Arrow, Oklahoma); Ashlee Allison Rempel (Tulsa, Oklahoma); Charles Justin Van De Wiele (Tulsa, Oklahoma) |
| ABSTRACT | Therapies using IL-18 alone or in combination with IL-7 for rebuilding weakened immune systems by increasing progenitor cell yields from bone marrow stem cells and/or increasing stem cell engraftment in bone marrow. |
| FILED | Friday, November 20, 2015 |
| APPL NO | 14/947722 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 38/20 (20130101) Original (OR) Class A61K 38/2046 (20130101) A61K 38/2046 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950043 | Feldman |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Brian Jay Feldman (Berkeley, California) |
| ABSTRACT | Modulation of the ADAMTS1 signaling pathway alters the commitment of progenitor cells to a muscle fate; and increases muscle mass. |
| FILED | Friday, November 15, 2013 |
| APPL NO | 14/442704 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 38/4886 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0659 (20130101) C12N 9/6494 (20130101) C12N 2501/734 (20130101) Enzymes C12Y 304/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950044 | Dempsey |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Edward C. Dempsey (Aurora, Colorado) |
| ABSTRACT | The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming from the inventor's discovery that Neprilysin is expressed at reduced levels in disease tissues. |
| FILED | Thursday, October 09, 2014 |
| APPL NO | 14/510738 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/4886 (20130101) Original (OR) Class A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6494 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/96419 (20130101) G01N 2333/96497 (20130101) G01N 2500/10 (20130101) G01N 2800/7014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950047 | Bae et al. |
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| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Jooeun Bae (West Roxbury, Massachusetts); Nikhil C. Munshi (Needham, Massachusetts); Kenneth C. Anderson (Wellesley, Massachusetts) |
| ABSTRACT | The disclosure features, inter alia, immunogenic XBP1-, CD138-, and CS1-derived peptides (and pharmaceutical compositions thereof). The peptides can be used in a variety of methods such as methods for inducing an immune response, methods for producing an antibody, and methods for treating a cancer (e.g., breast cancer, colon cancer, pancreatic cancer, a blood cancer, e.g., leukemia or a plasma cell disorder such as multiple myeloma or Waldenstrom's macroglobulinemia). The peptides (and pharmaceutical compositions comprising the peptides) can be used, e.g., in a method of treating a precancerous condition such as smoldering multiple myeloma. The peptides can also be included in MHC molecule multimer compositions and used in, e.g., methods for detecting a T cell in a population of cells. |
| FILED | Tuesday, November 05, 2013 |
| APPL NO | 14/440442 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/193 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) A61K 38/1774 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/55511 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950057 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Madison, Wisconsin); Jihui Ping (Madison, Wisconsin) |
| ABSTRACT | The invention provides a composition useful to prepare high titer influenza viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, that confer enhanced growth in cells in culture, such as MDCK cells, or in eggs. |
| FILED | Tuesday, July 15, 2014 |
| APPL NO | 14/332121 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950060 | Harrison et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Stephen C. Harrison (Brighton, Massachusetts); Bing Chen (Chestnut Hill, Massachusetts); Dan H. Barouch (Boston, Massachusetts); Joseph P. Nkoloa (Watertown, Massachusetts); Michael Scott Seaman (West Roxbury, Massachusetts) |
| ABSTRACT | Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided. |
| FILED | Tuesday, May 16, 2017 |
| APPL NO | 15/596312 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Original (OR) Class A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16051 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950063 | Reed et al. |
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| FUNDED BY |
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| APPLICANT(S) | Infectious Disease Research Institute (Seattle, Washington) |
| ASSIGNEE(S) | Infectious Disease Research Institute (Seattle, Washington) |
| INVENTOR(S) | Steven G. Reed (Bellevue, Washington); Darrick Carter (Seattle, Washington) |
| ABSTRACT | Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogeneous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier. |
| FILED | Tuesday, December 23, 2014 |
| APPL NO | 14/581062 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 39/04 (20130101) A61K 39/008 (20130101) A61K 39/0011 (20130101) A61K 39/35 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 45/06 (20130101) A61K 2039/55511 (20130101) A61K 2039/55572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950072 | Hanes et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Justin Scot Hanes (Baltimore, Maryland); Peter Anthony Campochiaro (Baltimore, Maryland); Jie Fu (Baltimore, Maryland) |
| ABSTRACT | Controlled release dosage formulations for the delivery of one or more HIF-1 inhibitors are provided. The controlled release formulations contain one or more HIF-1 inhibitors conjugated to or dispersed in a polymeric vehicle. The one or more HIF-1 inhibitors can be dispersed or encapsulated in a polymeric matrix. In some embodiments, the one or more HIF-1 inhibitors are covalently bound to a polymer, forming a polymer-drug conjugate. Polymeric vehicles can be formed into implants, microparticles, nanoparticles, or combinations thereof. Controlled release HIF-1 formulations provide prolonged therapeutic benefit while lowering side effects by releasing low levels of one or more HIF-1 inhibitors and/or HIF-1 inhibitor conjugates over a prolonged period of time. Controlled release dosage formulations can be used to treat or prevent a disease or disorder in a patient associated with vascularization, including cancer, obesity, and ocular diseases such as wet AMD. |
| FILED | Monday, January 19, 2015 |
| APPL NO | 14/599853 |
| ART UNIT | 1673 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/16 (20130101) A61K 9/0048 (20130101) A61K 31/704 (20130101) A61K 47/50 (20170801) A61K 47/488 (20130101) A61K 47/48192 (20130101) A61K 47/48215 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950075 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | The University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Son N. Nguyen (Amherst, Massachusetts); Cedric E. Bobst (Northampton, Massachusetts); Igor A. Kaltashov (Leverett, Massachusetts) |
| ABSTRACT | The invention in some aspects provides compounds useful for targeting bacterial infections. In some embodiments, the compounds comprise a transferrin receptor ligand covalently linked to a bactericidal agent. In some embodiments, the bactericidal agent is a bactericidal peptide, such as a glycoside hydrolase (e.g., lysozyme). |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776082 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/47 (20130101) A61K 47/483 (20130101) Original (OR) Class A61K 47/644 (20170801) Peptides C07K 14/79 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 9/2462 (20130101) Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950081 | Williams |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nature Technology Corporation (Lincoln, Nebraska) |
| ASSIGNEE(S) | Nature Technology Corporation (Lincoln, Nebraska) |
| INVENTOR(S) | James A. Williams (Lincoln, Nebraska) |
| ABSTRACT | Improved DNA vaccine plasmids are disclosed that contain novel immunostimulatory RNA compositions. The improved plasmids eliminate all extraneous sequences, incorporate a novel antibiotic free short RNA based selectable marker, increase eukaryotic expression using a novel chimeric promoter, improve yield and stability during bacterial production, and improve immunostimulation. These vectors are utilized in immunization to elicit improved immune responses or therapy to induce type 1 interferon production. |
| FILED | Monday, June 29, 2015 |
| APPL NO | 14/753438 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 48/00 (20130101) A61K 48/0066 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/55561 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/117 (20130101) C12N 2310/11 (20130101) C12N 2310/17 (20130101) C12N 2310/111 (20130101) C12N 2310/532 (20130101) C12N 2320/30 (20130101) C12N 2320/50 (20130101) C12N 2710/10322 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2800/106 (20130101) C12N 2800/107 (20130101) C12N 2830/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950097 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hyun-Su Lee (Wayne, Pennsylvania); Russell Composto (Philadelphia, Pennsylvania); David M. Eckmann (Wynnewood, Pennsylvania); Noreen J. Hickok (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hyun-Su Lee (Wayne, Pennsylvania); Russell Composto (Philadelphia, Pennsylvania); David M. Eckmann (Wynnewood, Pennsylvania); Noreen J. Hickok (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention relates to a multifunctional chitosan grafted surface. Specifically, the invention relates to a chitosan modified with a quaternary ammonium salt (CH-Q) grafted surface that provides various functional properties, including stability (pH 3-9) and unique pH dependent swelling and antibacterial properties. |
| FILED | Tuesday, February 07, 2012 |
| APPL NO | 13/983847 |
| ART UNIT | 1673 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/085 (20130101) Original (OR) Class A61L 31/10 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0004 (20130101) B29C 47/0021 (20130101) B29C 49/0005 (20130101) B29C 51/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950101 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Smith (Lyndhurst, Ohio); Markus Lorenz (Karlsruhe, Germany); David Dudzinski (Strongsville, Ohio); Hsiang Ming Chen (Latham, New York); Peter A. Chapman, Jr. (East Schodack, New York); Charles J. Prisco (Saratoga Springs, New York); Nicholas G. Vitale (Albany, New York); Stephan Weber (Lyndhurst, Ohio) |
| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | William Smith (Lyndhurst, Ohio); Markus Lorenz (Karlsruhe, Germany); David Dudzinski (Strongsville, Ohio); Hsiang Ming Chen (Latham, New York); Peter A. Chapman, Jr. (East Schodack, New York); Charles J. Prisco (Saratoga Springs, New York); Nicholas G. Vitale (Albany, New York); Stephan Weber (Lyndhurst, Ohio) |
| ABSTRACT | A blood pump (20) includes a stator assembly comprising a motor stator (52), a fluid inlet (24), and a fluid outlet (26). A rotor assembly includes a motor rotor (54) and an impeller (40) rotatable about an axis (44) to move fluid from the inlet (24) to the outlet (26). An outflow sheath (300) directs the flow along the outside of the pump (20). |
| FILED | Monday, May 14, 2012 |
| APPL NO | 13/470631 |
| ART UNIT | 3766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/12 (20130101) A61M 1/101 (20130101) A61M 1/122 (20140204) A61M 1/125 (20140204) A61M 1/127 (20130101) A61M 1/1008 (20140204) A61M 1/1012 (20140204) A61M 1/1015 (20140204) A61M 1/1031 (20140204) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950987 | Sang |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina Agricultural and Technical State University (Greensboro, North Carolina) |
| ASSIGNEE(S) | North Carolina Agricultural and Technical State University (Greensboro, North Carolina) |
| INVENTOR(S) | Shengmin Sang (Concord, North Carolina) |
| ABSTRACT | The present invention provides novel aspirin derivatives useful for preventing and/or treating cancer. The novel compounds of this invention may be particularly useful for the prevention and/or treatment of cancers affecting the gastrointestinal system, such as colorectal cancer. |
| FILED | Monday, November 20, 2017 |
| APPL NO | 15/817844 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/616 (20130101) Acyclic or Carbocyclic Compounds C07C 49/86 (20130101) C07C 49/835 (20130101) C07C 69/78 (20130101) Original (OR) Class C07C 69/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951007 | Malladi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Venkata L. Malladi (Miami, Florida); Adam J. Sobczak (Boca Raton, Florida); Lisa Schneper (Miramar, Florida); Kalai Mathee (Miami, Florida); Stanislaw F. Wnuk (Miami, Florida) |
| ABSTRACT | Compounds of Formula (I) are disclosed herein and their use in inhibiting quorum sensing in bacteria. |
| FILED | Tuesday, January 19, 2016 |
| APPL NO | 15/000176 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/4015 (20130101) A61K 31/4025 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 207/12 (20130101) C07D 207/267 (20130101) Original (OR) Class C07D 207/273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951014 | Silverman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Qing Jing (Morton Grove, Illinois); Soosung Kang (Incheon, South Korea); Heng-Yen Wang (Evanston, Illinois) |
| ABSTRACT | Compounds and related methods for inhibition of mammalian and bacterial nitric oxide synthase. |
| FILED | Wednesday, November 04, 2015 |
| APPL NO | 14/932587 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/444 (20130101) Heterocyclic Compounds C07D 213/73 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 401/06 (20130101) C07D 401/10 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951024 | Zheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio); University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio); Univeristy of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Yi Zheng (Cincinnati, Ohio); Matthew Wortman (Ft Wright, Kentucky) |
| ABSTRACT | Provided are inhibitors of Rho GTPase activation, and, in particular, compounds that inhibit RhoA activation by an RhoGEF. Also provided are related pharmaceutical compositions and methods. Also provided are methods of inhibiting Rho GTPase activation. Also provided are methods of screening for compounds that inhibit Rho GTPase activation by a RhoGEF. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/644476 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/498 (20130101) A61K 31/4152 (20130101) Heterocyclic Compounds C07D 231/36 (20130101) Original (OR) Class C07D 403/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951046 | Herz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Algomedix, Inc. (Mill Creek, Washington) |
| ASSIGNEE(S) | Algomedix, Inc. (Mill Creek, Washington) |
| INVENTOR(S) | Jeffrey M. Herz (Mill Creek, Washington); Edward A Kesicki (Bothell, Washington) |
| ABSTRACT | This disclosure relates to polycyclic heteroaromatic compounds useful as TRPA1 modulators, as well as compositions and methods of treating pain that include the compounds. |
| FILED | Wednesday, July 06, 2016 |
| APPL NO | 15/203774 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/46 (20130101) A61K 31/46 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/415 (20130101) A61K 31/415 (20130101) A61K 31/444 (20130101) A61K 31/485 (20130101) A61K 31/485 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/497 (20130101) A61K 31/497 (20130101) A61K 31/498 (20130101) A61K 31/498 (20130101) A61K 31/513 (20130101) A61K 31/513 (20130101) A61K 31/536 (20130101) A61K 31/536 (20130101) A61K 31/537 (20130101) A61K 31/537 (20130101) A61K 31/538 (20130101) A61K 31/538 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/4045 (20130101) A61K 31/4045 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/4545 (20130101) A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 491/107 (20130101) C07D 491/113 (20130101) C07D 495/10 (20130101) C07D 498/04 (20130101) C07D 513/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951055 | Dockendorff et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Chris Dockendorff (Milwaukee, Wisconsin); Willmen Youngsaye (Cumberland, Rhode Island); Partha Pratim Nag (Somerville, Massachusetts); Timothy A. Lewis (Marlborough, Massachusetts); Sivaraman Dandapani (Malden, Massachusetts); Benito Munoz (Newtonville, Massachusetts); Patrick Faloon (Cambridge, Massachusetts); Thomas Nieland (Somerville, Massachusetts); Monty Krieger (Needham, Massachusetts); Miao Yu (Quincy, Massachusetts) |
| ABSTRACT | This application describes compounds and methods that can inhibit Scavenger receptor class B, type I (SR-BI) activity, which compounds and methods can used, for example, to mediate high-density lipoprotein (HDL) lipid uptake and treat hepatitis C viral infections. |
| FILED | Monday, October 21, 2013 |
| APPL NO | 14/436626 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 277/44 (20130101) C07D 417/04 (20130101) Original (OR) Class C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 491/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951069 | Fuller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rodin Therapeutics, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Rodin Therapeutics, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, II (Stonington, Connecticut) |
| ABSTRACT | Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2). |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 15/867982 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951074 | Bradner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | James E. Bradner (Weston, Massachusetts); Dennis Buckley (Boston, Massachusetts) |
| ABSTRACT | The present disclosure provides compounds of Formula (I), and pharmaceutically compositions thereof. Compounds of Formula (I) have been found to bind bromodomains and/or bromodomain-containing proteins (e.g., bromo and extra terminal (BET) proteins). Also provided are methods, uses, and kits of the compounds and pharmaceutical compositions for inhibiting the activity (e.g., increased activity) of bromodomains and/or bromodomain-containing proteins and for treating and/or preventing in a subject diseases associated with bromodomains or bromodomain-containing proteins (e.g., proliferative diseases, cardiovascular diseases, viral infections, fibrotic diseases, neurological diseases, metabolic diseases, endocrine diseases, and radiation poisoning). The compounds, pharmaceutical compositions, and kits are also useful for male contraception. |
| FILED | Tuesday, February 07, 2017 |
| APPL NO | 15/426660 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 475/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951097 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (La Jolla, California) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wei Zhu (Urbana, Illinois); Steffen Lindert (San Diego, California); Yonghui Zhang (Beijing, China PRC); William Sinko (La Jolla, California); Kai Li (Urbana, Illinois); James Andrew McCammon (La Jolla, California); Eric Oldfield (Champaign, Illinois) |
| ABSTRACT | With the rise in resistance to antibiotics such as methicillin, there is a need for new drugs. The invention provides small molecules that inhibit cellular drug targets such as UPPS and FPPS by interacting with binding pockets, thereby preventing enzyme function. Compounds described herein are also active against Staphylococcus aureus (MIC90˜0.25 μg/mL), can potently synergize with methicillin (fractional inhibitory concentration index=0.25), and are protective in a mouse infection model. The invention therefore provides numerous compounds for anti-bacterial treatments and for restoring sensitivity to drugs such as methicillin, using combination therapies. |
| FILED | Wednesday, December 04, 2013 |
| APPL NO | 14/649153 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/167 (20130101) A61K 31/506 (20130101) A61K 31/551 (20130101) A61K 31/4178 (20130101) A61K 31/4439 (20130101) A61K 31/7034 (20130101) A61K 31/7056 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 233/24 (20130101) C07D 239/06 (20130101) C07D 239/28 (20130101) C07D 243/04 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/26 (20130101) Original (OR) Class C07H 15/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951099 | Verdine et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Gregory L. Verdine (Boston, Massachusetts); Christian E. Schafmeister (Somerville, Massachusetts) |
| ABSTRACT | The present invention provides novel stabilized crosslinked compounds having secondary structure motifs, libraries of these novel compounds, and methods for the synthesis of these compounds libraries thereof. The synthesis of these novel stabilized compounds involves (1) synthesizing a peptide from a selected number of natural or non-natural amino acids, wherein the peptide comprises at least two moieties capable of undergoing reaction to promote carbon-carbon bond formation; and (2) contacting the peptide with a reagent to generate at least one crosslinker and to effect stabilization of a secondary structure motif. The present invention, in a preferred embodiment, provides stabilized p53 donor helical peptides. Additionally, the present invention provides methods for disrupting the p53/MDM2 binding interaction comprising (1) providing a crosslinked stabilized α-helical structure; and (2) contacting the crosslinked stabilized α-helical structure with MDM2. |
| FILED | Thursday, October 06, 2016 |
| APPL NO | 15/287513 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/02 (20130101) Peptides C07K 1/00 (20130101) Original (OR) Class C07K 1/04 (20130101) C07K 1/10 (20130101) C07K 1/047 (20130101) C07K 1/113 (20130101) C07K 14/001 (20130101) C07K 14/4746 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951102 | Miller, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Francis J. Miller, Jr. (Coralville, Iowa); Jennifer Streeter (Iowa City, Iowa) |
| ABSTRACT | An isolated peptide or fusion having the peptide useful to interfere with the phosphorylation of Nox1, block or inhibit binding of NoxA1 activation domain (AD) to Nox1, and/or prevent or inhibit assembly of the p47phox/NoxA1 complex with Nox1, or a vector encoding the peptide or fusion thereof, and methods of using the peptide, fusion or vector are provided. |
| FILED | Friday, April 17, 2015 |
| APPL NO | 14/689803 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class C07K 2319/01 (20130101) C07K 2319/09 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951106 | Guan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yongjun Guan (Clarksville, Maryland); George Lewis (Baltimore, Maryland); Anthony Devico (Alexandria, Virginia); Mohammad Sajadi (Cockeysville, Maryland); Tongyun Liu (Abingdon, Maryland); Marzena Pazgier (Mt. Airy, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Yongjun Guan (Clarksville, Maryland); George Lewis (Baltimore, Maryland); Anthony Devico (Alexandria, Virginia); Mohammad Sajadi (Cockeysville, Maryland); Tongyun Liu (Abingdon, Maryland); Marzena Pazgier (Mt. Airy, Maryland) |
| ABSTRACT | Fusion proteins comprising a portion of the HIV-1 Env protein (gp120 and gp140) and single-chain fragment V regions (ScFv) of an enhancing antibody that exhibits binding specificity for HIV-1 Env protein are disclosed that may serve in immunogenic formulations for vaccination against HIV-1 infection, as well as methods of generating an immune response using the fusion proteins. |
| FILED | Wednesday, December 04, 2013 |
| APPL NO | 14/649565 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/162 (20130101) C07K 16/1063 (20130101) C07K 2317/31 (20130101) C07K 2317/34 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) C07K 2318/10 (20130101) C07K 2319/00 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951107 | Rome et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Regets of the University of California (Oakland, California); The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Leonard H. Rome (Los Angeles, California); Valerie A. Kickhoefer (Sherman Oaks, California); Glen Nemerow (La Jolla, California); Cheng-Yu Lai (La Jolla, California); Christopher Wiethoff (Downers Grove, Illinois); Mu Han (Los Angeles, California) |
| ABSTRACT | The invention relates to compositions of vault complexes containing recombinant membrane lytic proteins, such as an adenovirus protein VI lytic domain, and methods of using the vault complexes to facilitate delivery and entry of a biomolecule into a cell or subject. |
| FILED | Thursday, September 24, 2015 |
| APPL NO | 14/863750 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/435 (20130101) C07K 14/485 (20130101) C07K 2319/00 (20130101) C07K 2319/70 (20130101) C07K 2319/75 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1077 (20130101) C12N 15/87 (20130101) C12N 15/88 (20130101) C12N 2710/10322 (20130101) Enzymes C12Y 204/0203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951111 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Howard M. Johnson (Gainesville, Florida); Chulbul M. Ahmed (Gainesville, Florida) |
| ABSTRACT | The subject invention pertains to agonist peptides of type I interferons and methods of using the peptides. These peptides are based on the amino acid sequence of the C-terminus region of the type I IFN molecules and are capable of binding to the cytoplasmic domain of type I IFN receptors. Surprisingly, these peptides were found to possess the same or similar biological activity as that associated with the full-length, mature type I IFN proteins, even though these peptides do not bind to the extracellular domain of the type I IFN receptors. In one embodiment, the peptide is a peptide of IFNα. In another embodiment, the peptide is a peptide of IFNβ. Exemplified peptides of the invention include those having SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:38, SEQ ID NO:39, and SEQ ID NO:40. The subject peptides have been shown to effect increased resistance to viral infection. Peptides of the invention can be used to treat or prevent viral infections, to treat oncological disorders, and to treat autoimmune disorders, such as multiple sclerosis. |
| FILED | Wednesday, December 11, 2013 |
| APPL NO | 14/103564 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/16 (20130101) A61K 38/17 (20130101) A61K 38/21 (20130101) A61K 38/212 (20130101) A61K 38/215 (20130101) A61K 38/217 (20130101) A61K 38/1709 (20130101) A61K 45/06 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 16/2866 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951117 | Russell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Stephen James Russell (Rochester, Minnesota); Shruthi Naik (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials related to vesicular stomatitis viruses. For example, vesicular stomatitis viruses, nucleic acid molecules encoding VSV polypeptides, methods for making vesicular stomatitis viruses, and methods for using vesicular stomatitis viruses to treat cancer are provided. |
| FILED | Wednesday, August 24, 2016 |
| APPL NO | 15/246189 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/766 (20130101) A61K 38/215 (20130101) A61K 48/005 (20130101) Peptides C07K 14/565 (20130101) C07K 14/705 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/20232 (20130101) C12N 2760/20243 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951118 | Kitchen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Scott G. Kitchen (Los Angeles, California); Jerome A. Zack (Tarzana, California); Otto O. Yang (Los Angeles, California); Irvin Chen (Palos Verdes Estates, California); Masakazu Kamata (Los Angeles, California) |
| ABSTRACT | The HIV-specific cytotoxic T lymphocyte (CTL) response is a critical component in controlling HIV replication and is an important part of the ultimate failure to eradicate the virus. Disclosed herein are methods for genetically enhancing the HIV-specific CTL response to allow long-term viral suppression or viral clearance. Human hematopoietic stem cells (HSCs) were genetically modified such that they differentiate into mature CTLs that will kill HIV infected cells. As disclosed herein, the functional effector cells are not human leukocyte antigen (HLA)-restricted. As disclosed herein, stem cells are transduced with non-HLA restricted chimeric antigen receptors (CARs) that allow the recognition of HIV or HIV-infected cells when expressed by a CTL. These CARs are hybrid molecules that contain an extracellular HIV recognition domain and an intracellular TCR-zeta signaling domain. The CTL response may be enhanced through the targeting of T cell inhibitory receptors. The methods and compositions disclosed herein may be used to engineer antiviral immunity and HIV-specific CTL responses in vivo. Also disclosed herein are methods and compositions for the treatment of chronic viral infections such as HIV. |
| FILED | Friday, August 01, 2014 |
| APPL NO | 14/908476 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/28 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70514 (20130101) Original (OR) Class C07K 16/1045 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0647 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951122 | Marasco et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Burnham Institute for Medical Research (La Jolla, California) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); BURNHAM INSTITUTE FOR MEDICAL RESEARCH (La Jolla, California) |
| INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts); Jianhua Sui (Waltham, Massachusetts); Robert C. Liddington (La Jolla, California) |
| ABSTRACT | The invention provides human scFv antibodies and monoclonal antibodies that neutralize influenza virus. Also provided are methods of treating and/or preventing a influenza related disease or disorder such bird flu The invention also provides methods of vaccinating a patient against influenza. Also provided are methods of diagnosing influenza-related diseases or disorders and methods of detecting the presence of a influenza in a sample. |
| FILED | Monday, August 12, 2013 |
| APPL NO | 13/965092 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 14/005 (20130101) C07K 16/1018 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/52 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951149 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Rensselaer Polytechnic Institute (Troy, New York); NUTECH VENTURES (Lincoln, Nebraska) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Rensselaer Polyechnic Institute (Troy, New York); NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Jian Liu (Chapel Hill, North Carolina); Yongmei Xu (Durham, North Carolina); Robert J. Linhardt (Albany, New York); Edward Harris (Lincoln, Nebraska) |
| ABSTRACT | Methods and systems for synthesizing heparin compounds are provided. The chemoenzymatic synthesis of structurally homogeneous low molecular weight heparins that have a reversible anticoagulant activity is provided. Also disclosed are heparin compounds having anticoagulant activity, including a binding affinity to antithrombin and an anti-Xa activity, but no detectable anti-lla activity. Additionally, provided are synthetic, low-molecular weight heparin compounds with reversible anticoagulant activity, where the anticoagulant activity is reversible by protamine. |
| FILED | Tuesday, June 17, 2014 |
| APPL NO | 14/898865 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0003 (20130101) C08B 37/0075 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 5/10 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) C12P 19/18 (20130101) C12P 19/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951311 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
| INVENTOR(S) | Hua Gu (New York, New York); Richard Hodes (Bethesda, Maryland); Jeffrey J. Chiang (Herndon, Virginia); Ihnkyung Jang (Jupiter, Florida) |
| ABSTRACT | The invention provides an isolated, purified population of human cells comprising CD8+ T cells with reduced Cbl-b activity. The invention provides uses of such cells in methods for inducing or enhancing an anti-tumor immune response in a subject. These methods comprise: (a) providing a cell population, from a subject or from another source, which comprises CD8+ T cells, (b) reducing Cbl-b activity in the CD8+ T-cells, (c) administering the cells of step (b) to the subject. The invention provides methods for making CD8+ T cells that do not require stimulation through a co-receptor in order for the cell to become activated or proliferated in response to contact via its T cell receptor. Such methods are based upon reducing function of Cbl-b. The invention also provides methods for identifying agents which affect Cbl-b expression or activity. |
| FILED | Friday, April 01, 2016 |
| APPL NO | 15/089016 |
| ART UNIT | 1674 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/57 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2501/998 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 2333/9015 (20130101) G01N 2333/70514 (20130101) G01N 2333/70517 (20130101) G01N 2333/70539 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951315 | Schlegel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Richard Schlegel (Rockville, Maryland); Xuefeng Liu (Gaithersburg, Maryland) |
| ABSTRACT | The present invention is directed towards methods of culturing non-keratinocyte epithelial cells, with the methods comprising culturing non-keratinocyte epithelial cells in the presence of feeder cells and a calcium-containing medium while inhibiting the activity of Rho kinase (ROCK) in the feeder cell, the non-keratinocyte epithelial cells or both during culturing. |
| FILED | Wednesday, February 10, 2016 |
| APPL NO | 15/040783 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) C12N 5/0625 (20130101) C12N 5/0631 (20130101) C12N 5/0683 (20130101) Original (OR) Class C12N 5/0688 (20130101) C12N 2500/05 (20130101) C12N 2500/40 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/33 (20130101) C12N 2501/39 (20130101) C12N 2501/727 (20130101) C12N 2502/13 (20130101) C12N 2502/1323 (20130101) C12N 2503/02 (20130101) C12N 2510/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951316 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Yanhong Shi (Arcadia, California); Man Lun Yip (Honolulu, Hawaii); Wendong Li (Duarte, California) |
| ABSTRACT | Described herein, inter alia, are methods and compositions useful for induced pluripotent stem cell reprogramming. |
| FILED | Wednesday, January 07, 2015 |
| APPL NO | 14/591341 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 2501/603 (20130101) C12N 2506/02 (20130101) C12N 2506/1307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951317 | Smith et al. |
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| FUNDED BY |
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| APPLICANT(S) | NOVAVAX, INC. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | NOVAVAX, INC. (Gaithersburg, Maryland) |
| INVENTOR(S) | Gale Smith (Gaithersburg, Maryland); Yingyun Wu (Clarksburg, Maryland); Michael J. Massare (Mt. Airy, Maryland); Peter M. Pushko (Frederick, Maryland); Margaret Nathan (Montgomery Village, Maryland); Thomas Kort (Germantown, Maryland); Robin Robinson (Gaithersburg, Maryland) |
| ABSTRACT | This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs. |
| FILED | Thursday, October 06, 2016 |
| APPL NO | 15/287433 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/5258 (20130101) A61K 2039/55505 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/01 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 9/2402 (20130101) C12N 2710/14143 (20130101) C12N 2760/16122 (20130101) C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2760/16171 (20130101) C12N 2760/16222 (20130101) C12N 2760/16223 (20130101) C12N 2760/16251 (20130101) C12N 2770/20022 (20130101) C12N 2770/20023 (20130101) C12N 2770/20051 (20130101) C12N 2800/22 (20130101) Enzymes C12Y 302/01018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951321 | Hanzel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| INVENTOR(S) | David K. Hanzel (Palo Alto, California); Geoff Otto (Brookline, Massachusetts); Paul S. Peluso (Newark, California); Thang Pham (Mountain View, California); David R. Rank (Pacific Grove, California); Fred Christians (Los Altos Hills, California); Arekadiusz Bibillo (Cupertino, California); Insil Park (Fremont, California); Sonya Clark (Oakland, California); John Lyle (Fremont, California) |
| ABSTRACT | Compositions that include polymerases with features for improving entry of nucleotide analogs into active site regions and for coordinating with the nucleotide analogs in the active site region are provided. Methods of making the polymerases and of using the polymerases in sequencing and DNA replication and amplification as well as kinetic models of polymerase activity and computer-implemented methods of using the models are also provided. |
| FILED | Tuesday, December 06, 2016 |
| APPL NO | 15/370461 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1252 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Enzymes C12Y 207/07007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951330 | Crary et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | John Crary (Brooklyn, New York); Ismael Santa-Maria Perez (New York, New York) |
| ABSTRACT | This invention relates to the treatment and prevention of Alzheimer's disease (AD), tangle-predominant dementia (TPD) and other diseases associated with abnormal tau expression, e.g., tauopathies, using the 3′untranslated region (UTR) of the tau messenger RNA (mRNA) as a target, specifically using microRNAs that regulate the expression of tau. This invention is also in the field of screening for, identifying, and diagnosing such diseases. Specifically, this invention provides biomarkers for these diseases in the form of microRNAs. |
| FILED | Friday, July 11, 2014 |
| APPL NO | 14/903164 |
| ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951335 | Li |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Jian-Dong Li (Marietta, Georgia) |
| ABSTRACT | The present invention is based, in part, on our studies of molecular pathways that include the deubiquitinase CYLD. Accordingly, the present invention features, inter alia, nucleic acid constructs that express CYLD or a biologically active variant thereof (e.g., a variant including the catalytic domain), nucleic acids that inhibit the expression of a negative regulator of CYLD (e.g., PDE4B or LNK2), nucleic acids that modulate the expression of downstream CYLD targets (e.g., Akt, by inhibiting or promoting the expression of the downstream target), compositions including one or more of these types of constructs (e.g., pharmaceutical compositions), kits including one or more of the compositions described herein and instructions for use, screening methods to identify therapeutic agents {e.g., anti-inflammatory agents) that upregulate CYLD, downregulate a negative regulatory of CYLD, or modulate (e.g., inhibit) a downstream CYLD target (e.g., Akt), and various methods of treatment including the administration of the nucleic acids described above, protein biotherapeutics, and/or small molecules, alone or in combination, to address cancer, inflammation, and fibrosis. The compositions described herein can be used in the preparation of a medicament (e.g., used in the preparation of a medicament to treat cancer, inflammation, fibrosis, or one or more of the more specific conditions described herein). |
| FILED | Tuesday, April 09, 2013 |
| APPL NO | 14/391890 |
| ART UNIT | 1673 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/277 (20130101) A61K 31/685 (20130101) A61K 31/713 (20130101) A61K 31/4015 (20130101) A61K 31/4174 (20130101) A61K 31/7064 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Enzymes C12Y 301/04017 (20130101) C12Y 304/19012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951340 | Lesser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Cambridge, Massachusetts); President and Fellows of Harvard College (Boston, Massachusetts) |
| INVENTOR(S) | Cammie Lesser (Cambridge, Massachusetts); Amy Jo Wagers (Cambridge, Massachusetts); Analise Z. Reeves (Brookline, Massachusetts) |
| ABSTRACT | The methods and compositions described herein relate to the delivery of polypeptides to a target cell, e.g. by utilizing engineered non-pathogenic bacteria comprising a type three secretion system (T3SS) and T3SS-compatible substrates. In one aspect, described herein are non-pathogenic microbial cells that have been engineered to express both a functional type three secretion system (T3SS) and at least one polypeptide that is compatible with the T3SS. Due to the wide variety of polypeptides that can be delivered to a target eukaryotic cell using the compositions and systems described herein, a commensurately wide variety of applications is contemplated, e.g. therapeutics and reprogramming. |
| FILED | Thursday, March 06, 2014 |
| APPL NO | 14/772697 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) Original (OR) Class C12N 15/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951344 | Alper et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Hal Alper (Austin, Texas); Kathleen Curran (Emeryville, California) |
| ABSTRACT | Provided herein are exogenous terminator sequences for use in fungi cell transcriptional termination. |
| FILED | Friday, October 09, 2015 |
| APPL NO | 14/879946 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/80 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951349 | Rabinovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Peter M. Rabinovich (Madison, Connecticut); Sherman M. Weissman (New Haven, Connecticut) |
| ABSTRACT | Compositions for transient but prolonged exogenous mRNA expression through the use of the transcription system of negative strand RNA viruses, and methods of use thereof are disclosed. In some embodiments, the system contains only RNAs and does not include any DNA molecules. The compositions typically include an RNA template unit (rTeUn) that includes a virus regulatory sequences operably linked to a coding sequence of interest. The rTeUn is typically transfected to a host cell's cytoplasm in the presence of virus expression system proteins that mediate replication of the rTeUn and transcription of the transgene. The rTeUn RNA bonded to viral proteins exhibits high resistance to degradation, prolonged duration of expression, and is free of viral genes. The compositions can be used to reprogram cell. For example, the compositions and methods can be used to redirected lymphocytes to target cancer cells, or to dedifferentiate somatic cells into induce pluripotent stem cells. |
| FILED | Thursday, September 27, 2012 |
| APPL NO | 14/343817 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2760/18843 (20130101) C12N 2760/18852 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951353 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Mahendra S. Rao (Timonium, Maryland); Nasir Malik (Bethesda, Maryland); Raymond Funahashi (West Chester, Pennsylvania); Jizhong Zou (Bethesda, Maryland) |
| ABSTRACT | Described herein are recombinant polynucleotide-binding polypeptides, recombinant fusion proteins made with the described polynucleotide-binding polypeptides, methods of using the described recombinant polynucleotide-binding polypeptides and recombinant fusion proteins to modify genomic DNA of cells and, in some embodiments, create recombinant cells. Methods are also provided herein for genetically modifying a neuronal stem cell. Methods are also provided for treating a neurological disorder in a subject that include the administration of genetically modified neuronal stem cells produced by the methods disclosed herein. |
| FILED | Friday, November 14, 2014 |
| APPL NO | 15/035958 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2501/60 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951374 | Murphy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | William L. Murphy (Waunakee, Wisconsin); Siyoung Choi (Ithaca, New York); Xiaohua Yu (Madison, Wisconsin) |
| ABSTRACT | Disclosed are methods for cell transfection and regulating cellular behavior. More particularly, the present disclosure relates to methods of non-viral cell transfection and regulating cellular behavior using mineral coatings that allow for the enhanced transfection of cells. The mineral coatings bind polynucleotides and provide a source of calcium and phosphate ions to enhance transfection. The present disclosure also provides a high throughput platform for screening non-viral transfection of cells. The methods of the present disclosure also provide an advantageous polynucleotide delivery platform because the mineral coatings may be deposited on various medical device materials after being specifically developed using the high throughput screening platform. |
| FILED | Tuesday, February 19, 2013 |
| APPL NO | 13/769993 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951383 | Turner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| INVENTOR(S) | Stephen Turner (Seattle, Washington); Jon Sorenson (Alameda, California); Kevin Travers (Menlo Park, California); Cheryl Heiner (La Honda, California) |
| ABSTRACT | Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Methods are provided that include linking forward and reverse strands of a double stranded segment to form circular template molecules, and obtaining sequence data from the circular template molecule to identify modified bases, for example including the use of bisulfite treatment. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid. |
| FILED | Wednesday, September 21, 2016 |
| APPL NO | 15/271915 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2525/117 (20130101) C12Q 2525/307 (20130101) C12Q 2527/113 (20130101) C12Q 2527/113 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952128 | Carragher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Bridget Carragher (New York, New York); Clinton S. Potter (San Diego, California); Tilak Jain (San Diego, California) |
| ABSTRACT | The invention provides systems or apparatuses for dispensing aqueous materials for electron microscopy (EM). The systems allow dispensing of aqueous materials onto an EM sample grid at individual specimen locations in an ordered array of specimen locations, with each individual specimen location in the array of locations. The systems contain a holder for reversibly receiving an EM sample grid, and a dispenser containing one or more dispensing elements that are configured to discretely dispense one or more aqueous solutions from the dispensing elements onto a plurality of individual specimen locations. The dispenser is able to provide an ordered array of discrete specimen locations discontinuous with one another. In the systems, at least one dispensing element is configured to dispense picoliter volumes of one or more of the aqueous solutions. Additionally, the systems contain a drive mechanism to position the EM sample grid relative to the one or more dispensing elements, as well as one or more reservoirs operably linked to the dispenser for holding the one or more aqueous solutions to be discretely dispensed onto each individual specimen location in the array of locations. |
| FILED | Tuesday, October 04, 2016 |
| APPL NO | 15/285070 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) Original (OR) Class G01N 1/30 (20130101) G01N 1/31 (20130101) G01N 1/312 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) H01J 37/261 (20130101) H01J 2237/20 (20130101) H01J 2237/202 (20130101) H01J 2237/204 (20130101) H01J 2237/208 (20130101) H01J 2237/2007 (20130101) H01J 2237/2602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952148 | Georgakoudi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Irene Georgakoudi (Acton, Massachusetts); Sharad Gupta (Medford, Massachusetts); Martin Hunter (Bradford, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Boston, Massachusetts) |
| INVENTOR(S) | Irene Georgakoudi (Acton, Massachusetts); Sharad Gupta (Medford, Massachusetts); Martin Hunter (Bradford, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
| ABSTRACT | In one aspect, the present invention generally provides methods for characterizing mineralization of a material, e.g., a biomaterial, by illuminating the material with radiation and analyzing radiation scattered from the material in response to the illumination. For example, in some embodiments, a material can be illuminated with polarized radiation at a plurality of wavelengths and the elastically scattered radiation corresponding to two or more of those wavelengths can be collected at two polarizations: one parallel and the other perpendicular to the illumination polarization. A differential intensity of the scattered radiation at the two polarizations can be analyzed as a function of wavelength to obtain information regarding the morphology of mineral deposits in the sample. Further, the total scattered radiation can be analyzed to derive information regarding the level of mineralization. |
| FILED | Thursday, February 19, 2009 |
| APPL NO | 12/867383 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/47 (20130101) Original (OR) Class G01N 2021/4792 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952149 | Superfine et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Richard Superfine (Chapel Hill, North Carolina); Bruce J. Oberhardt (Raleigh, North Carolina); Richard Chasen Spero (Chapel Hill, North Carolina); Michael Richard Falvo (Durham, North Carolina); Briana Lee Fiser (High Point, North Carolina); Russell Morton Taylor, II (Pittsboro, North Carolina); Robert Michael Judith (Chapel Hill, North Carolina) |
| ABSTRACT | Methods, systems, and computer readable media for determining physical properties of a specimen in a portable point of care device are disclosed. According to one aspect, a method includes placing a specimen onto an active surface that includes a plurality of microposts extending outwards from a substrate, wherein each micropost includes a proximal end attached to the substrate and a distal end opposite the proximal end and generating an actuation force in proximity to the micropost array that compels at least some of the microposts to exhibit motion. The method further includes detecting light that is emitted by an illumination source and interacts with the active surface while the at least some microposts exhibit motion in response to the actuation force, measuring data that represents the detected light interacting with the active surface, and determining at least one physical property of the specimen based on the measured data. |
| FILED | Monday, December 02, 2013 |
| APPL NO | 14/648845 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) Original (OR) Class G01N 21/59 (20130101) G01N 21/82 (20130101) G01N 27/22 (20130101) G01N 27/72 (20130101) G01N 33/49 (20130101) G01N 33/4905 (20130101) G01N 2021/825 (20130101) G01N 2201/02 (20130101) G01N 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952198 | Lindsay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS on behalf of ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents On Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Stuart Lindsay (Phoenix, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ABSTRACT | Embodiments of the present disclosure are directed to methods, systems and devices, for analyzing the molecules. For example, in some embodiments, a system is provided which includes a first volume of conducting fluid, a second volume of conducting fluid, an orifice in communication with the first and second volumes of fluid, and means for applying an electric potential difference between the first and second volumes of fluid. In some embodiments, a conjugate product is provided which includes charged polymers each having attached thereto at least one first molecule for analysis, where the product carries a predetermined charge greater than the charge on the first molecule, and upon dissolving a product in the first volume of fluid, the product is directed into the orifice. |
| FILED | Wednesday, March 05, 2014 |
| APPL NO | 14/773072 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/12 (20130101) G01N 27/44704 (20130101) G01N 27/44747 (20130101) G01N 27/44756 (20130101) G01N 33/5438 (20130101) G01N 33/6803 (20130101) G01N 33/6848 (20130101) G01N 33/48721 (20130101) Original (OR) Class G01N 2333/952 (20130101) G01N 2570/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/255 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952199 | Ayyub et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Children's National Medical Center (Washington, District of Columbia); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Children's National Medical Center (Washington, District of Columbia); The United States of America, As Represented By The Secretary, Dept. Of Health And Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Omar Bilal Ayyub (Potomac, Maryland); Adam Michael Behrens (Olney, Maryland); Peter Kofinas (North Bethesda, Maryland); Marshall Lynn Summar (Washington, District of Columbia); Juan Manuel Cabrera-Luque (Rockville, Maryland); Gary Cunningham (Washington, District of Columbia); Anton Simeonov (Bethesda, Maryland); Juan Marugan (Gaithersburg, Maryland) |
| ABSTRACT | The present disclosure relates to a bio-sensor capable of measuring the total concentration of one or a plurality of ammonia or ammonium ions with the use of indophenol reagents in the presence of an ionomer. In some embodiments, the biosensor comprises a perflurinated membrane that comprises an ionomer in contact with an alkaline buffer in a vessel configured to receive a sample, such as whole blood. The disclosure also relates to a method of detecting or quantifying the ammonia or ammonium ion concentration in whole blood in a point of care biosensor without reliance on gas chromatography or any measurement that takes more than about twenty minutes. |
| FILED | Tuesday, September 02, 2014 |
| APPL NO | 14/915602 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 27/327 (20130101) G01N 27/3275 (20130101) G01N 33/84 (20130101) G01N 33/4925 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2800/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952204 | Hickman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Hickman (Orlando, Florida); Xiufang Guo (Oviedo, Florida); Mercedes Gonzalez (Casselberry, Florida); Maria Stancescu (Oviedo, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | James Hickman (Orlando, Florida); Xiufang Guo (Oviedo, Florida); Mercedes Gonzalez (Casselberry, Florida); Maria Stancescu (Oviedo, Florida) |
| ABSTRACT | A method for forming neuromuscular junctions includes forming functional neuromuscular junctions between motoneurons and muscle cells by co-culturing one or more human motoneurons and one or more rat muscle cells in a substantially serum-free medium. A synthetic mammalian neuromuscular junction includes a human motoneuron functionally linked to a rat muscle cell in a substantially serum-free medium. An artificial substrate may be used to support the one or more neuromuscular junctions. |
| FILED | Friday, May 06, 2011 |
| APPL NO | 13/102672 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0697 (20130101) C12N 2500/90 (20130101) C12N 2501/01 (20130101) C12N 2501/13 (20130101) C12N 2501/41 (20130101) C12N 2501/58 (20130101) C12N 2501/105 (20130101) C12N 2501/385 (20130101) C12N 2502/081 (20130101) C12N 2502/1335 (20130101) C12N 2533/20 (20130101) C12N 2535/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) Original (OR) Class G01N 33/6872 (20130101) G01N 33/6887 (20130101) G01N 33/48728 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952205 | Abeytunge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Sanjee Abeytunge (Brooklyn, New York); Yongbiao Li (Dobbs Ferry, New York); Bjorg Larson (Brooklyn, New York); Milind Rajadhyaksha (New York, New York); Ricardo Toledo-Crow (New York, New York) |
| ABSTRACT | Exemplary systems, methods and non-transitory computer-accessible mediums are provided for generating a mosaic image of a large area of tissue with microscopic resolution by acquiring a plurality of rectangular-shaped long strips of images of the tissue and stitching the strips together along their lengths. |
| FILED | Thursday, April 04, 2013 |
| APPL NO | 13/856672 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 33/5091 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/367 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952214 | Siman |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Robert Siman (Wilmington, Delaware) |
| ABSTRACT | The invention relates to methods for providing prognosis, diagnosis, monitoring and treatment of a mild traumatic brain injury (mTBI) in a subject, including a sports-related concussion. The invention further relates to assessing the severity of brain damage resulting from mTBI in a subject, including in a subject who has not undergone a CT scan following the injury. For example, the methods of the invention can be used to determine the suitability for someone who has suffered a sports-related injury to return to play that sport. This invention also relates to methods of predicting risk for developing brain damage and long-term dysfunction in a subject having suffered mTBI. |
| FILED | Monday, November 10, 2014 |
| APPL NO | 14/537642 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2333/47 (20130101) G01N 2333/4703 (20130101) G01N 2800/28 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952216 | Visel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Axel Visel (El Cerrito, California); John L. R. Rubenstein (San Francisco, California); Ying-Jiun (Jasmine) Chen (South San Francisco, California); Len A. Pennacchio (Sebastopol, California); Daniel Vogt (Burlingame, California); Cory Nicholas (San Francisco, California); Arnold Kriegstein (Mill Valley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Axel Visel (El Cerrito, California); John L. R. Rubenstein (San Francisco, California); Ying-Jiun (Jasmine) Chen (South San Francisco, California); Len A. Pennacchio (Sebastopol, California); Daniel Vogt (Burlingame, California); Cory Nicholas (San Francisco, California); Arnold Kriegstein (Mill Valley, California) |
| ABSTRACT | Herein are described a set of novel specific human enhancers for specific forebrain cell types used to study and select for human neural progenitor cells. This approach enables the ability to generate interneurons from human ES, iPS and iN cells, making them available for human transplantation and for molecular/cellular analyzes. These approaches are also directly applicable to generating other neuronal cell types, such as cortical and striatal projection neurons, which have implications for many human diseases. |
| FILED | Friday, October 10, 2014 |
| APPL NO | 14/512306 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2830/008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/56966 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952225 | Bowler |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL JEWISH HEALTH (Denver, Colorado) |
| ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
| INVENTOR(S) | Russell P. Bowler (Denver, Colorado) |
| ABSTRACT | Disclosed are methods of identifying, predicting and treating subjects at risk for exacerbation or the presence of a respiratory disease, by detecting expression levels of one or more proteins associated with the respiratory disease, wherein said one or more proteins is selected from the group of CCL24, IL2RA, APOA4, GC, IgA, LPA, KLK3 F, FAS, NRCAM, TNFRSFIOC, IL12B, IL23A, RAGE, CCL20, ICAM1, SERPINA7, CDH13 and CDH1, and wherein said respiratory disease may be chronic obstructive pulmonary disease or emphysema. |
| FILED | Friday, January 23, 2015 |
| APPL NO | 15/113593 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/50 (20130101) G01N 2800/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952227 | Gruber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York); John B. Pierce Laboratory (New Haven, Connecticut) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York); John B. Pierce Laboratory (New Haven, Connecticut) |
| INVENTOR(S) | David F. Gruber (Fair Lawn, New Jersey); Jean P. Gaffney (Union, New Jersey); Vincent A. Pieribone (Madison, Connecticut) |
| ABSTRACT | Fluorescent proteins (Chlopsid FP I from Kaupichthys hyoproroides and Chlopsid FP II from Kaupichthys n. sp.) are used in a method for detecting bilirubin. The proteins are based on transcriptome analysis of the false moray eels, Kaupichthys hyoproroides and Kaupichthys n. sp., the later representing a heretofore undescribed species. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/348563 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/728 (20130101) Original (OR) Class G01N 2333/43504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952231 | Strongin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Portland State University (Portland, Oregon) |
| ASSIGNEE(S) | Portland State University (Portland, Oregon) |
| INVENTOR(S) | Robert Strongin (Portland, Oregon); Martha Sibrian-Vazquez (Portland, Oregon); Jialu Wang (Portland, Oregon); Lei Wang (Camas, Washington); Jorge O. Escobedo-Cordova (Portland, Oregon) |
| ABSTRACT | Embodiments of methods and compounds for isolating and detecting lysophosphatidic acids (LPAs) are disclosed. Kits for performing the methods also are disclosed. LPAs are isolated from biological samples by liquid-liquid extraction followed by solid phase extraction. LPA species may be separated by HPLC, and the separated species may be identified and quantified. Also disclosed are embodiments of compounds capable of universally detecting a plurality of LPA species with substantially equivalent sensitivity. Embodiments of the disclosed compounds are useful for determination of total LPA concentration in a sample comprising a plurality of LPA species without separation of individual LPA species. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776273 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 491/22 (20130101) C07D 491/107 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953131 | Rossi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | John J. Rossi (Azusa, California); Ola Snove (Oslo, Norway); Ali Ehsani (West Covina, California); Pal Saetrom (Trondheim, Norway); Britta Vallazza (Hagen, Germany); Jane Zhang (South El Monte, California); Lars Aagaard (Ry, Denmark) |
| ABSTRACT | The present invention relates to novel short interfering RNA (siRNA) molecules that are multi-targeted. More specifically, the present invention relates to siRNA molecules that target two or more sequences. In one embodiment, multi-targeting siRNA molecules are designed to incorporate features of siRNA molecules and features of micro-RNA (miRNA) molecules. In another embodiment, multi-targeting siRNA molecules are designed so that each strand is directed to separate targets. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/273094 |
| ART UNIT | 1674 — Data Bases & File Management |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1132 (20130101) C12N 15/1135 (20130101) C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/51 (20130101) C12N 2310/53 (20130101) C12N 2320/30 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/02 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) Original (OR) Class G06F 19/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953209 | Adalsteinsson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Viktor A. Adalsteinsson (Wakefield, Massachusetts); Denis Loginov (Dorchester Center, Massachusetts); J. Christopher Love (Somerville, Massachusetts); Alan Stockdale (Providence, Rhode Island); Todd Gierahn (Brookline, Massachusetts) |
| ABSTRACT | Described herein are systems, methods, and apparatus for automatically identifying and recovering individual cells of interest from a sample of biological matter, e.g., a biological fluid. Also described are methods of enriching a cell type of interest. These systems, methods, and apparatus allow for coordinated performance of two or more of the following, e.g., all with the same device, thereby enabling high throughput: cell enrichment, cell identification, and individual cell recovery for further analysis (e.g., sequencing) of individual recovered cells. |
| FILED | Wednesday, March 30, 2016 |
| APPL NO | 15/085175 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 2300/12 (20130101) B01L 2300/0654 (20130101) B01L 2300/0829 (20130101) B01L 2300/0851 (20130101) B01L 2300/0896 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1425 (20130101) G01N 15/1463 (20130101) G01N 33/4833 (20130101) G01N 35/00029 (20130101) G01N 35/00871 (20130101) G01N 2015/0065 (20130101) G01N 2015/1006 (20130101) G01N 2035/00148 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/26 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/036 (20130101) G06K 9/00147 (20130101) Original (OR) Class G06K 9/4647 (20130101) G06K 9/4652 (20130101) G06K 9/4661 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953246 | Bouchard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Louis Bouchard (Los Angeles, California); Khalid Youssef (Los Angeles, California) |
| ABSTRACT | A noise removal method includes receiving in a de-noising system multiple noisy copies of a target image; providing the noisy copies as input data to the de-noising system in a training phase, and determine a noise distribution for the plurality of noisy copies. The method further includes, for n stages of the de-noising system, transforming the input data into an output; reconstructing the output; and providing the reconstructed output as input data. The method may further include receiving a new image and generating a de-noised image based on the determined noise distribution. |
| FILED | Wednesday, December 16, 2015 |
| APPL NO | 14/971775 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) Original (OR) Class G06K 9/6273 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 2207/10024 (20130101) G06T 2207/10032 (20130101) G06T 2207/10061 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10116 (20130101) G06T 2207/10132 (20130101) G06T 2207/20072 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954362 | Low et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Steven H. Low (La Canada, Canada); Qiuyu Peng (Pasadena, California) |
| ABSTRACT | Node controllers and power distribution networks in accordance with embodiments of the invention enable distributed power control. One embodiment includes a node controller including a distributed power control application; a plurality of node operating parameters describing the operating parameter of a node and a set of at least one node selected from the group consisting of an ancestor node and at least one child node; wherein send node operating parameters to nodes in the set of at least one node; receive operating parameters from the nodes in the set of at least one node; calculate a plurality of updated node operating parameters using an iterative process to determine the updated node operating parameters using the node operating parameters that describe the operating parameters of the node and the set of at least one node, where the iterative process involves evaluation of a closed form solution; and adjust node operating parameters. |
| FILED | Tuesday, May 26, 2015 |
| APPL NO | 14/722075 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/00 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 12/6418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 09949927 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ting Xu (Berkeley, California); He Dong (Albany, California); Jessica Shu (San Francisco, California); Nikhil Dube (Berkeley, California) |
| ABSTRACT | The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer blocks. The conjugates can self-assemble to form helix bundle subunits, which in turn assemble to provide micellar nanocarriers for drug cargos and other agents. Particles containing the conjugates and methods for forming the particles are also disclosed. |
| FILED | Thursday, September 18, 2014 |
| APPL NO | 14/490336 |
| ART UNIT | 1676 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 47/42 (20130101) A61K 47/62 (20170801) A61K 47/6907 (20170801) A61K 51/1227 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950067 | Gainer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Diffusion Pharmaceuticals, LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | Diffusion Pharmaceuticals, LLC (Charlottesville, Virginia) |
| INVENTOR(S) | John L. Gainer (Charlottesville, Virginia); Marc Lanz (Reitnau, Switzerland) |
| ABSTRACT | The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans. |
| FILED | Monday, January 11, 2016 |
| APPL NO | 14/993047 |
| ART UNIT | 1671 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 31/11 (20130101) A61K 31/202 (20130101) A61K 41/0038 (20130101) Original (OR) Class A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Acyclic or Carbocyclic Compounds C07C 57/03 (20130101) C07C 57/13 (20130101) C07C 69/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950096 | Guelcher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Scott A. Guelcher (Franklin, Tennessee); Edna Margarita Prieto (Nashville, Tennessee); Jerald E. Dumas (Atlanta, Georgia); Katarzyna Jadwiga Zienkiewicz (Nashville, Tennessee); Jonathan Page (Mount Juliet, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Scott A. Guelcher (Franklin, Tennessee); Edna Margarita Prieto (Nashville, Tennessee); Jerald E. Dumas (Atlanta, Georgia); Katarzyna Jadwiga Zienkiewicz (Nashville, Tennessee); Jonathan Page (Mount Juliet, Tennessee) |
| ABSTRACT | The present invention encompasses the finding that certain treatments (e.g., surface modifications) to particulate materials can provide surprising and unexpected benefits and/or features to composites and/or compositions as described herein. In some embodiments, such benefits and/or features may render particular composites and/or compositions particularly useful in a certain therapeutic context (e.g, for repair of tibial plateau, femoral head, craniofacial, or lateral mandibular body defects). The present invention demonstrates that certain composites and/or compositions wherein the particular material is or comprises defatted bone have surprising and beneficial attributes. |
| FILED | Wednesday, January 12, 2011 |
| APPL NO | 13/005528 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/46 (20130101) Original (OR) Class A61L 27/48 (20130101) A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/446 (20130101) A61L 2300/406 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950422 | Kornbluh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Roy David Kornbluh (Palo Alto, California); Alexander Steele Kernbaum (Sunnyvale, California); Thomas Low (Belmont, California); Katherine Goss Witherspoon (San Francisco, California); Brian Keith McCoy (Sunnyvale, California); Adam Arnold Edward Ziemba (Menlo Park, California); Paul Michael Birkmeyer (Redwood City, California); Richard M. Mahoney (Los Altos, California) |
| ABSTRACT | A flexible exosuit includes rigid and flexible elements configured to couple forces to a body of a wearer. Further, the flexible exosuit includes flexible linear actuators and clutched compliance elements to apply and/or modulate forces and/or compliances between segments of the body of the wearer. The flexible exosuit further includes electronic controllers, power sources and sensors. The flexible exosuit can be configured to apply forces to the body of the wearer to enable a variety of applications. In some examples, the flexible exosuit can be configured to augment the physical strength or endurance of the wearer. In some examples, the flexible exosuit can be configured to train the wearer to perform certain physical tasks. In some examples, the flexible exosuit can be configured to record physical activities of the wearer. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 14/865029 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class B25J 9/104 (20130101) B25J 9/1615 (20130101) B25J 9/1633 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 28/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/36429 (20130101) G05B 2219/39345 (20130101) G05B 2219/40305 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950790 | Keennon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AeroVironment, Inc. (Monrovia, California) |
| ASSIGNEE(S) | AEROVIRONMENT, INC. (Monrovia, California) |
| INVENTOR(S) | Matthew Todd Keennon (Simi Valley, California); Karl Robert Klingebiel (Simi Valley, California); Alexander Andryukov (Simi Valley, California); Bart Dean Hibbs (Simi Valley, California); John Peter Zwaan (Simi Valley, California) |
| ABSTRACT | Heavier-than-air, aircraft having flapping wings, e.g., ornithopters, where angular orientation control is effected by variable differential sweep angles of deflection of the flappable wings in the course of sweep angles of travel and/or the control of variable wing membrane tension. |
| FILED | Wednesday, March 05, 2014 |
| APPL NO | 14/198418 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 19/00 (20130101) B64C 33/02 (20130101) B64C 33/025 (20130101) Original (OR) Class B64C 2201/10 (20130101) B64C 2201/025 (20130101) B64C 2201/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950802 | Grip et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Robert Erik Grip (Rancho Palos Verdes, California); Blaine Knight Rawdon (San Pedro, California) |
| ABSTRACT | An aircraft wing has a plurality of wing segments mounted on a wing spar by joints that allow relative movement between the spar and the wing segments. Tuning of coefficients of thermal expansion is employed to reduce induced stresses from changes in temperature. |
| FILED | Monday, October 12, 2015 |
| APPL NO | 14/880278 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/18 (20130101) B64C 3/22 (20130101) B64C 3/26 (20130101) B64C 3/182 (20130101) B64C 3/185 (20130101) B64C 3/187 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) Original (OR) Class B64D 2211/00 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/44 (20130101) Y02T 50/62 (20130101) Y02T 50/64 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950961 | Goswami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ramasis Goswami (Alexandria, Virginia); Syed B. Qadri (Fairfax Station, Virginia); Manoj K. Kolel-Veetil (Alexandria, Virginia); Noam Bernstein (Alexandria, Virginia); Raymond M. Gamache (Indian Head, Maryland) |
| ABSTRACT | A method and resulting composition made by: providing boron carbide and a dopant selected from silicon, aluminum, magnesium, and beryllium; and ball milling the boron carbide with the dopant until at least one out of fifteen of the boron and/or carbon atoms of the boron carbide are substituted with the dopant. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/093737 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/563 (20130101) Original (OR) Class C04B 35/62615 (20130101) C04B 2235/401 (20130101) C04B 2235/402 (20130101) C04B 2235/428 (20130101) C04B 2235/761 (20130101) C04B 2235/3821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951221 | Esser-Kahn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Aaron P. Esser-Kahn (Champaign, Illinois); Hefei Dong (Urbana, Illinois); Piyush R. Thakre (Urbana, Illinois); Jason F. Patrick (Urbana, Illinois); Nancy R. Sottos (Champaign, Illinois); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois) |
| ABSTRACT | A thermally degradable polymeric fiber comprising a polymeric fiber matrix including a poly(hydroxyalkanoate) and a metal in the form of a compound selected from the group consisting of an alkaline earth metal oxide, a tin salt of a mono- or di-carboxylic acid, and scandium triflate (Sc(0Tf)3), where the concentration of the metal in the fiber matrix is at least 0.1 wt %. |
| FILED | Tuesday, January 27, 2015 |
| APPL NO | 14/606553 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0007 (20130101) B29C 47/0014 (20130101) B29C 67/202 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/20 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Original (OR) Class Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/06 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/04 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2958 (20150115) Y10T 428/249978 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951392 | Jewett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael C. Jewett (Evanston, Illinois); Jennifer A. Schoborg (Evanston, Illinois); Charles Eric Hodgman (Evanston, Illinois); Mark J. Anderson (Wilmette, Illinois) |
| ABSTRACT | Methods and kits are provided for calibrating a cell-free protein synthesis reaction for optimal activity. The method includes the steps of providing an extract competent for cell-free protein synthesis (CFPS); performing cell-free protein synthesis with the extract; measuring a first reaction end-point where in vitro protein synthesis plateaus; measuring a second reaction end-point where Energy Charge of the extract declines to a level in a range from about 0.40 to about 0.80 of Energy Charge of a control extract; and adjusting Energy Charge of the extract to a level in a range from about 0.80 to about 1.0 of the control extract. |
| FILED | Monday, March 16, 2015 |
| APPL NO | 14/659206 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) C12P 21/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951444 | Dzenis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Yuris Dzenis (Lincoln, Nebraska) |
| ABSTRACT | A method of fabricating a continuous nanofiber is described. The method includes preparing a solution of one or more polymers and one or more solvents and electrospinning the solution by discharging the solution through one or more liquid jets into an electric field to yield one or more continuous nanofibers. The electrospinning process (i) highly orients one or more polymer chains in the one or more continuous nanofibers along a fiber axis of the one or more continuous nanofibers, and (ii) suppresses polymer crystallization in the one or more continuous nanofibers. The one or more continuous nanofibers can have diameters below about 250 nanometers and exhibit an increase in fiber strength and modulus while maintaining strain at failure, resulting in an increase in fiber toughness. |
| FILED | Thursday, December 12, 2013 |
| APPL NO | 14/104930 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) D01D 5/003 (20130101) D01D 5/0038 (20130101) D01D 5/0046 (20130101) D01D 5/0092 (20130101) D01D 10/02 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/02 (20130101) D01F 6/18 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/298 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951640 | Westphal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | William I. Westphal (Avon, Indiana); Clayton C. Smith (New Braunfels, Texas) |
| ABSTRACT | A structure providing compliance and sealing between ceramic or ceramic composite (CMC) part and a metallic part has an interface component for centering the CMC part in the metallic part, thus reducing thermal stress motion of the CMC component. In gas turbine engine applications, the structure comprises a CMC blade track inserted in a clip placed within a metallic hanger. The clip provides for radial compliance and secures controlled leakage of cooling air required to ensure that acceptable temperatures are maintained for the metallic structures. A washer is positioned adjacent to the clip provide for axial orientation of the blade track. |
| FILED | Friday, December 27, 2013 |
| APPL NO | 14/142292 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/00 (20130101) F01D 11/006 (20130101) Original (OR) Class F01D 25/28 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/30 (20130101) F05D 2260/94 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4932 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951643 | Duguay |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Brian Duguay (Berwick, Maine) |
| ABSTRACT | An active clearance control system of a gas turbine engine includes an actuation cylinder, a puller engaged with an air seal segment and damped with respect to the actuation cylinder, and a full-hoop thermal control ring that at least partially supports the air seal segment. The puller may move the air seal segment between an extended radially contracted BOAS position and a retracted radially expanded BOAS position. |
| FILED | Thursday, February 06, 2014 |
| APPL NO | 14/781168 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/14 (20130101) F01D 11/16 (20130101) F01D 11/20 (20130101) F01D 11/22 (20130101) Original (OR) Class F01D 25/24 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) F05D 2270/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951717 | Stambaugh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Craig T. Stambaugh (Tolland, Connecticut) |
| ABSTRACT | This disclosure relates to a variable area nozzle of a gas turbine engine. The variable area nozzle includes, among other things, a control unit, a translatable structure, and a plurality of actuators configured to adjust the position of the translatable structure. The plurality of actuators are fluidly coupled to a common fluid source. The control unit is configured to provide instructions to at least one of the actuators to compensate for an asymmetric load from the translatable structure. |
| FILED | Wednesday, April 15, 2015 |
| APPL NO | 14/687302 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Jet-propulsion Plants F02K 1/76 (20130101) F02K 1/763 (20130101) F02K 1/1223 (20130101) Original (OR) Class F02K 3/10 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2270/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951721 | Kupratis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Daniel Bernard Kupratis (Wallingford, Connecticut); Walter A Ledwith, Jr. (Marlborough, Connecticut); Christopher J Hanlon (Sturbridge, Massachusetts) |
| ABSTRACT | A gas turbine engine includes an auxiliary airflow control system to provide selective communication of a portion of a second stream from a second stream flow path into a third stream flow path, the auxiliary airflow control system in communication with a high temperature flow sourced from the turbine section. |
| FILED | Tuesday, October 21, 2014 |
| APPL NO | 14/519272 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/10 (20130101) Jet-propulsion Plants F02K 3/075 (20130101) Original (OR) Class F02K 3/077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951753 | Sinclair et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nathan A. Sinclair (Santa Barbara, California); David P. Wilkinson (Ventura, California); Jeffrey P. Kilpatrick (Ventura, California) |
| ABSTRACT | In various embodiments, an offshore electrical energy generator is disclosed. The generator includes a buoy configured to float on a body of water. A wind turbine is mounted to the buoy. An air storage tank is configured for submersion. An air compressor is stowed within the buoy and coupled to the wind turbine and configured to charge the air storage tank in response to receiving wind energy collected by the wind turbine. An expansion turbine is stowed within the buoy and is configured to receive compressed air stored within the air storage tank and to decompress the compressed air to generate electrical energy. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/158815 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 15/10 (20130101) F01D 25/10 (20130101) F01D 25/12 (20130101) Wind Motors F03D 9/001 (20130101) F03D 9/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951825 | Darrow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | David A. Darrow (Stratford, Connecticut); Thomas L. Tully, Jr. (Oxford, Connecticut) |
| ABSTRACT | A multi-plate clutch apparatus is provided and includes a multi-plate clutch disposed to occupy clutch and non-clutch positions at which rotation of an input shaft is and is not transmitted to an output shaft, respectively, a drive element disposed about the multi-plate clutch and configured to generate rotational energy and a linear actuator disposed to convert the rotational energy of the drive element to linear movement by which the multi-plate clutch is controllable to occupy one of the clutch and non-clutch positions. |
| FILED | Tuesday, June 24, 2014 |
| APPL NO | 14/915098 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) B64C 27/22 (20130101) B64C 27/82 (20130101) B64C 2027/8236 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 35/00 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 13/52 (20130101) Original (OR) Class F16D 23/12 (20130101) F16D 2023/123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952033 | Martini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Joerg Martini (San Francisco, California); Marshall W. Bern (San Carlos, California); Noble M. Johnson (Menlo Park, California); Peter Kiesel (Palo Alto, California); Doron Kletter (San Mateo, California); Bowen Cheng (Atherton, California); Michael I. Recht (Mountain View, California) |
| ABSTRACT | Spatially modulated light emanating from an object moving along a flow path is used to determine various object characteristics including object length along the flow direction. Light emanating from at least one object moving along in a flow path along a flow direction of a spatial filter is sensed. The intensity of the sensed light is time modulated according to features of the spatial filter. A time varying electrical signal is generated which includes a plurality of pulses in response to the sensed light. Pulse widths of at least some of the pulses are measured at a fraction of a local extremum of the pulses. The length of the object along the flow direction is determined based on the measured pulse widths. |
| FILED | Friday, February 14, 2014 |
| APPL NO | 14/181530 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/043 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) G01N 2015/1447 (20130101) G01N 2015/1493 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/36 (20130101) G01P 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952096 | Kats et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Mikhail A. Kats (Cambridge, Massachusetts); Romain Blanchard (Cambridge, Massachusetts); Patrice Genevet (Cambridge, Massachusetts); Federico Capasso (Cambridge, Massachusetts) |
| ABSTRACT | A spectral encoder includes a thin layer of lossy dielectric material whose thickness varies transversely from 0 to a thickness of about λ/4n (e.g., <100 nm), where λ is the wavelength of incident radiation and n is the dielectric material's refractive index. The dielectric layer reflects (and/or transmits) light at a wavelength that depends on the layer's thickness. Because the dielectric layer's thickness varies, different parts of the dielectric layer may reflect (transmit) light at different wavelengths. For instance, shining white light on a dielectric layer with a linearly varying thickness may produce a rainbow-like reflected (and/or transmitted) beam. Thus, the spectral encoder maps different wavelengths to different points in space. This mapping can be characterized by a transfer matrix which can be used to determine the spectrum of radiation incident on the spectral encoder from the spatial intensity distribution of the radiation reflected (and/or transmitted) by the spectral encoder. |
| FILED | Monday, June 03, 2013 |
| APPL NO | 14/404834 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/021 (20130101) G01J 3/26 (20130101) G01J 3/0205 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 3/0218 (20130101) G01J 3/2803 (20130101) G01J 2003/1213 (20130101) Optical Elements, Systems, or Apparatus G02B 5/22 (20130101) G02B 5/207 (20130101) G02B 5/223 (20130101) G02B 5/286 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02162 (20130101) H01L 31/02168 (20130101) H01L 31/02325 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952156 | Boss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Pamela A. Boss (San Diego, California); Michael D. Putnam (San Diego, California); Gregory W. Anderson (San Diego, California) |
| ABSTRACT | An apparatus comprising: a direct push probe configured to be pushed into a subsurface soil environment; a transparent window mounted to a side of the probe; a white light source mounted within the probe and positioned such that when the white light source is activated only white light exits the window; an ultraviolet (UV) light source mounted within the probe and positioned such that when the UV light source is activated only UV light having a given wavelength exits the window; and an imaging system disposed within the probe and configured to capture a white-light-only-illuminated image and a UV-light-induced-fluorescence image of the subsurface soil environment at a given depth, wherein the imaging system comprises a longpass filter to filter out the UV light having the given wavelength. |
| FILED | Tuesday, June 30, 2015 |
| APPL NO | 14/788141 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6456 (20130101) Original (OR) Class G01N 33/24 (20130101) G01N 2201/062 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952352 | Kirby |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Stephen F. Kirby (Las Cruces, New Mexico) |
| ABSTRACT | A method and system configured to provide a weather forecast for a selected zone is provided. The method and system is configured to receive meteorological reports and locally sensed measurements. The information is transmitted to a weather model preprocessor disposed on the device which generates an analysis field. This information is passed to the weather model which is an executable program also disposed on the device. The weather model processes the analysis field generated by meteorological reports, large-scale initialization data and in-situ sensor values to generate an initial weather forecast. The weather model updates the initial weather forecast with real-time, high-resolution atmospheric measurements to generate a weather forecast more representative of the user's zone than that available from Internet/media outlets. Furthermore, because the weather model is run on the mobile device itself, staleness of the forecast will no longer be an issue, as forecasts can be generated on demand. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 14/866153 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952383 | Engheta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nader Engheta (Berwyn, Pennsylvania); Ashkan Vakil (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Nader Engheta (Berwyn, Pennsylvania); Ashkan Vakil (Philadelphia, Pennsylvania) |
| ABSTRACT | Graphene may support electromagnetic radiation and be able to support a variety of optical devices. In general, graphene may exhibit changeability in properties such as the conductivity and the like of graphene. Graphene may comprise carbon and be of a thickness of a single atomic layer. In another embodiment, Graphene may be thicker than a single atomic layer, but may be able to exhibit changeability in the properties noted above. Disclosed herein is the guiding and manipulating of optical signals on layers of graphene to create waveguides, ribbon waveguides, beamsplitters, lenses, attenuators, mirrors, scatterers, Fourier optics, Luneburg lenses, metamaterials and other optical devices. |
| FILED | Wednesday, June 08, 2011 |
| APPL NO | 13/805755 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) G02B 6/1226 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952438 | Broadhead et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Eric Wayne Broadhead (Wichita, Kansas); Daniel Charles Braasch (Marysville, Washington) |
| ABSTRACT | A method and apparatus for performing a task. The task is performed using a tool. Information received by a display system from the tool is displayed on a viewing area that is substantially transparent in the display system. The viewing area is configured to cover an eye and display the information in the viewing area. |
| FILED | Monday, October 29, 2012 |
| APPL NO | 13/663143 |
| ART UNIT | 2692 — Selective Visual Display Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0176 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952453 | Fainman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, None) |
| INVENTOR(S) | Yeshaiahu Fainman (San Diego, California); Alexei Smolyaninov (San Diego, California); Lin Pang (San Diego, California); Lindsay Freeman (San Diego, California); Maxim Abashin (San Diego, California) |
| ABSTRACT | Techniques, systems, and devices are disclosed for implementing nanostructures in the optical domain that highly localize the incident electromagnetic field to with a large spectral range from the visible to the infrared range. An optical nano antenna device is provided to include a substrate; a central conductive core formed on the substrate; and a peripheral conductive shell formed on the substrate and located peripheral to the central conductive core to surround at least a part of the central conductive core. The central conductive core and peripheral conductive shell form a coaxial structure with a dimension less than an optical wavelength of light. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/179930 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0102 (20130101) Original (OR) Class G02F 1/0136 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/12 (20130101) Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 9/04 (20130101) H01Q 9/0407 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952454 | Long et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James Peter Long (Accokeek, Maryland); Joshua D. Caldwell (Accokeek, Maryland); Jeffrey C. Owrutsky (Silver Spring, Maryland); Orest J. Glembocki (Alexandria, Virginia) |
| ABSTRACT | Optical devices that include one or more structures fabricated from polar-dielectric materials that exhibit surface phonon polaritons (SPhPs), where the SPhPs alter the optical properties of the structure. The optical properties lent to these structures by the SPhPs are altered by introducing charge carriers directly into the structures. The carriers can be introduced into these structures, and the carrier concentration thereby controlled, through optical pumping or the application of an appropriate electrical bias. |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493169 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/009 (20130101) G02F 1/29 (20130101) G02F 1/0126 (20130101) G02F 1/0136 (20130101) Original (OR) Class G02F 1/0333 (20130101) G02F 2202/30 (20130101) G02F 2203/13 (20130101) G02F 2203/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952557 | Shaltout et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Amr Shaltout (West Lafayette, Indiana); Sajid Choudhury (West Lafayette, Indiana); Alexander V. Kildishev (West Lafayette, Indiana); Alexandra Boltasseva (West Lafayette, Indiana); Vladimir M. Shalaev (West Lafayette, Indiana) |
| ABSTRACT | A device for producing a subwavelength hologram. The device comprises a metasurface layer attached to a substrate. The metasurface layer includes an array of plasmonic antennas that simultaneously encode both wavelength and phase information of light directed through the array to produce a hologram. The wavelength is determined by the size of the antennas, and the phase is determined by the orientation of the antennas. |
| FILED | Wednesday, May 11, 2016 |
| APPL NO | 15/152535 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/00 (20130101) G02B 1/002 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/00 (20130101) G02F 1/01 (20130101) Holographic Processes or Apparatus G03H 1/02 (20130101) Original (OR) Class G03H 1/024 (20130101) G03H 1/0244 (20130101) G03H 2001/026 (20130101) G03H 2001/2263 (20130101) G03H 2240/11 (20130101) G03H 2240/21 (20130101) Antennas, i.e Radio Aerials H01Q 15/0006 (20130101) H01Q 15/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953209 | Adalsteinsson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Viktor A. Adalsteinsson (Wakefield, Massachusetts); Denis Loginov (Dorchester Center, Massachusetts); J. Christopher Love (Somerville, Massachusetts); Alan Stockdale (Providence, Rhode Island); Todd Gierahn (Brookline, Massachusetts) |
| ABSTRACT | Described herein are systems, methods, and apparatus for automatically identifying and recovering individual cells of interest from a sample of biological matter, e.g., a biological fluid. Also described are methods of enriching a cell type of interest. These systems, methods, and apparatus allow for coordinated performance of two or more of the following, e.g., all with the same device, thereby enabling high throughput: cell enrichment, cell identification, and individual cell recovery for further analysis (e.g., sequencing) of individual recovered cells. |
| FILED | Wednesday, March 30, 2016 |
| APPL NO | 15/085175 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 2300/12 (20130101) B01L 2300/0654 (20130101) B01L 2300/0829 (20130101) B01L 2300/0851 (20130101) B01L 2300/0896 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1425 (20130101) G01N 15/1463 (20130101) G01N 33/4833 (20130101) G01N 35/00029 (20130101) G01N 35/00871 (20130101) G01N 2015/0065 (20130101) G01N 2015/1006 (20130101) G01N 2035/00148 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/26 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/036 (20130101) G06K 9/00147 (20130101) Original (OR) Class G06K 9/4647 (20130101) G06K 9/4652 (20130101) G06K 9/4661 (20130101) Pictorial Communication, e.g Television H04N 5/2256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953214 | Yin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for the State Universirty of New York (Binghamton, New York) |
| INVENTOR(S) | Lijun Yin (Vestal, New York); Michael Reale (Vestal, New York) |
| ABSTRACT | A gaze direction determining system and method is provided. A two-camera system may detect the face from a fixed, wide-angle camera, estimates a rough location for the eye region using an eye detector based on topographic features, and directs another active pan-tilt-zoom camera to focus in on this eye region. A eye gaze estimation approach employs point-of-regard (PoG) tracking on a large viewing screen. To allow for greater head pose freedom, a calibration approach is provided to find the 3D eyeball location, eyeball radius, and fovea position. Both the iris center and iris contour points are mapped to the eyeball sphere (creating a 3D iris disk) to get the optical axis; then the fovea rotated accordingly and the final, visual axis gaze direction computed. |
| FILED | Wednesday, March 09, 2016 |
| APPL NO | 15/065472 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 3/00 (20130101) G06F 3/013 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0061 (20130101) G06K 9/00248 (20130101) G06K 9/00335 (20130101) Original (OR) Class G06K 9/00597 (20130101) G06K 9/00604 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 2207/30201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953246 | Bouchard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Louis Bouchard (Los Angeles, California); Khalid Youssef (Los Angeles, California) |
| ABSTRACT | A noise removal method includes receiving in a de-noising system multiple noisy copies of a target image; providing the noisy copies as input data to the de-noising system in a training phase, and determine a noise distribution for the plurality of noisy copies. The method further includes, for n stages of the de-noising system, transforming the input data into an output; reconstructing the output; and providing the reconstructed output as input data. The method may further include receiving a new image and generating a de-noised image based on the determined noise distribution. |
| FILED | Wednesday, December 16, 2015 |
| APPL NO | 14/971775 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) Original (OR) Class G06K 9/6273 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 2207/10024 (20130101) G06T 2207/10032 (20130101) G06T 2207/10061 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10116 (20130101) G06T 2207/10132 (20130101) G06T 2207/20072 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953261 | Friedman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Daniel J. Friedman (Sleepy Hollow, New York); Seongwon Kim (Old Tappan, New Jersey); Chung H. Lam (Peekskill, New York); Dharmendra S. Modha (San Jose, California); Bipin Rajendran (White Plains, New York); Jose A. Tierno (Stamford, Connecticut) |
| ABSTRACT | Embodiments of the invention relate to a neuromorphic network for producing spike-timing dependent plasticity. The neuromorphic network includes a plurality of electronic neurons and an interconnect circuit coupled for interconnecting the plurality of electronic neurons. The interconnect circuit includes plural synaptic devices for interconnecting the electronic neurons via axon paths, dendrite paths and membrane paths. Each synaptic device includes a variable state resistor and a transistor device with a gate terminal, a source terminal and a drain terminal, wherein the drain terminal is connected in series with a first terminal of the variable state resistor. The source terminal of the transistor device is connected to an axon path, the gate terminal of the transistor device is connected to a membrane path and a second terminal of the variable state resistor is connected to a dendrite path, such that each synaptic device is coupled between a first axon path and a first dendrite path, and between a first membrane path and said first dendrite path. |
| FILED | Thursday, January 07, 2016 |
| APPL NO | 14/990720 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/06 (20130101) Original (OR) Class G06N 3/08 (20130101) G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/0635 (20130101) Static Stores G11C 11/54 (20130101) G11C 13/0004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953284 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Patrick L. Smith (Arroyo Grande, California); Matthew Phillip Ferringer (Round Hill, Virginia) |
| ABSTRACT | Systems and methods for providing a prioritization of the focus and allocation of available resources and/or funding for due diligence analyses of a variety of candidate projects competing for limited funding are disclosed. Various methods may also determine a confidence level metrics associated with the information and/or estimates associated with the candidate projects. Evolutionary algorithms may be applied to perform multi-objective optimization of objectives based, at least in part, on currently available information and/or estimates associated with the candidate projects. A priority score, for the purpose of allocating due diligence attention and resources to increase confidence levels in assumptions associated with candidate projects, may be determined for a particular project based, at least in part, on the current confidence level associated with that particular project and the percentage of non-dominated projects within which the particular project is included. The optimization may be performed multiple times, such as once for every stakeholder that may have provided information and/or estimates associated with the candidate projects, to identify a plurality of non-dominated solutions to the optimization problem. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/837782 |
| ART UNIT | 3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06313 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953436 | Li |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dunling Li (Rockville, Maryland) |
| ASSIGNEE(S) | BTS Software Solutions, LLC (Columbia, Maryland) |
| INVENTOR(S) | Dunling Li (Rockville, Maryland) |
| ABSTRACT | A method for compressing data is disclosed. The method may include receiving data from one or more data sources. The method may also include selectively classifying the data into one or more data streams, the one or more data streams including at least PCM-encoded data and image data. The method may further include separately compressing the PCM-encoded data and the image data into first and second compressed bit-streams. The method may also include shuffling the first and second compressed bit-streams. |
| FILED | Tuesday, June 25, 2013 |
| APPL NO | 13/927028 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 9/00 (20130101) Original (OR) Class G06T 9/001 (20130101) Pictorial Communication, e.g Television H04N 19/12 (20141101) H04N 19/20 (20141101) H04N 19/50 (20141101) H04N 19/88 (20141101) H04N 19/119 (20141101) H04N 19/174 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953951 | Howard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emmett Howard (Tempe, Arizona); Nicholas Munizza (Gilbert, Arizona); Paul Yee (Chandler, Arizona); Michael Marrs (Phoenix, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Emmett Howard (Tempe, Arizona); Nicholas Munizza (Gilbert, Arizona); Paul Yee (Chandler, Arizona); Michael Marrs (Phoenix, Arizona) |
| ABSTRACT | Some embodiments include a method. The method can comprise: providing a carrier substrate; providing an adhesion modification layer over the carrier substrate; providing a device substrate; and coupling the device substrate and the carrier substrate together, the adhesion modification layer being located between the device substrate and the carrier substrate when the device substrate and the carrier substrate are coupled together. In these embodiments, the adhesion modification layer can be configured so that the device substrate couples indirectly with the carrier substrate by way of the adhesion modification layer with a first bonding force that is greater than a second bonding force by which the device substrate couples with the carrier substrate absent the adhesion modification layer. Other embodiments of related methods and devices are also disclosed. |
| FILED | Friday, November 11, 2016 |
| APPL NO | 15/349511 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/6835 (20130101) H01L 24/29 (20130101) H01L 24/83 (20130101) Original (OR) Class H01L 2221/6835 (20130101) H01L 2221/68318 (20130101) H01L 2221/68381 (20130101) H01L 2224/8309 (20130101) H01L 2224/83359 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954085 | Fay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| ASSIGNEE(S) | University of Notre Dame due Lac (South Bend, Indiana) |
| INVENTOR(S) | Patrick Fay (Granger, Indiana); Lina Cao (Notre Dame, Indiana); Debdeep Jena (Ithaca, New York); Wenjun Li (South Bend, Indiana) |
| ABSTRACT | A tunnel field-effect transistor device includes a p-type GaN source layer, an ntype GaN drain layer, and an interlayer interfaced between the source-layer and the drain layer. These devices employ polarization engineering in GaN/InN heterojunctions to achieve appreciable interband tunneling current densities. In one example, the interlayer includes an Indium Nitride (InN) layer. In one example, the interlayer includes a graded Indium gallium nitride layer and an InN layer. In one example, the interlayer may include a graded Indium gallium nitride (InxGa1-xN) layer and an Indium gallium nitride (InGaN) layer. In one example, the tunnel field-effect transistor device includes an in-line configuration. In one example, the tunnel field-effect transistor device includes a side-wall configuration. In one example, the tunnel field-effect transistor device includes a nanowire cylindrical gate-all-around geometry to achieve a high degree of gate electrostatic control. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 15/194039 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) H01L 29/0669 (20130101) H01L 29/2003 (20130101) H01L 29/42392 (20130101) H01L 29/66522 (20130101) H01L 29/66742 (20130101) H01L 29/66977 (20130101) Original (OR) Class H01L 29/78618 (20130101) H01L 29/78681 (20130101) H01L 29/78696 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954090 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL LABORATORIES LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | David F. Brown (Woodland Hills, California); Keisuke Shinohara (Thousand Oaks, California); Miroslav Micovic (Thousand Oaks, California); Andrea Corrion (Santa Monica, California) |
| ABSTRACT | A monolithically integrated device includes a substrate, a first set of Group III nitride epitaxial layers grown for a first HFET on a first region of the substrate, and a second set of Group III nitride epitaxial layers for a second HFET grown on a second region of the substrate. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/148991 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8252 (20130101) H01L 21/26546 (20130101) H01L 27/095 (20130101) H01L 29/205 (20130101) H01L 29/2003 (20130101) H01L 29/7784 (20130101) Original (OR) Class H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954128 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Richard R. King (Thousand Oaks, California); Moran Haddad (Granada Hills, California); Philip T. Chiu (La Crescenta, California); Xingquan Liu (La Crescenta, California); Christopher M. Fetzer (Valencia, California) |
| ABSTRACT | The present disclosure generally relates to a solar cell device that a first Bragg reflector disposed below a first solar cell and a second Bragg reflector disposed below the first Bragg reflector, wherein the first solar cell comprises a dilute nitride composition and has a first bandgap, wherein the first Bragg reflector is operable to reflect a first range of radiation wavelengths back into the first solar cell and the second Bragg reflector is operable to reflect a third range of wavelengths back into the first solar cell, and the first Bragg reflector and the second Bragg reflector are operable to cool the solar cell device by reflecting a second range of radiation wavelengths that are outside the photogeneration wavelength range of the first solar cell or that are weakly absorbed by the first solar cell. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 14/993800 |
| ART UNIT | 1756 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/056 (20141201) Original (OR) Class H01L 31/0687 (20130101) H01L 31/03042 (20130101) H01L 31/03048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954191 | Bao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Zhenan Bao (Stanford, California); Chao Wang (Sunnyvale, California); Wen Ya Lee (Palo Alto, California); Guillaume Schweicher (Ixelles, Belgium); Desheng Kong (Palo Alto, California) |
| ABSTRACT | An electronic or optoelectronic device includes: (1) a semiconductor layer; (2) a pair of electrodes electrically coupled to the semiconductor layer; and (3) a dielectric layer in contact with the semiconductor layer and including a polar elastomer, where the elastomer has a glass transition temperature Tg that is no greater than 25° C. |
| FILED | Thursday, April 16, 2015 |
| APPL NO | 14/688683 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0036 (20130101) H01L 51/0043 (20130101) H01L 51/0516 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954486 | Ainspan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Herschel A. Ainspan (New Hempstead, New York); Mark A. Ferriss (Tarrytown, New York); Daniel J. Friedman (Sleepy Hollow, New York); Alexander V. Rylyakov (Mount Kisco, New York); Bodhisatwa Sadhu (White Plains, New York); Alberto Valdes-Garcia (Chappaqua, New York) |
| ABSTRACT | An apparatus comprises a digitally controlled circuit having a variable capacitance and a controller configured to adjust a magnitude of the variable capacitance of the digitally controlled circuit. The digitally controlled circuit comprises a plurality of gain elements, the plurality of gain elements comprising one or more positive voltage-to-frequency gain elements and one or more negative voltage-to-frequency gain elements. The controller is configured to adjust the magnitude of the capacitance by adjusting the gain provided by respective ones of the gain elements in an alternating sequence of the positive voltage-to-frequency gain elements and the negative voltage-to-frequency gain elements. |
| FILED | Tuesday, February 02, 2016 |
| APPL NO | 15/013649 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 1/00 (20130101) H03B 5/124 (20130101) H03B 5/1212 (20130101) H03B 5/1215 (20130101) H03B 5/1228 (20130101) Original (OR) Class H03B 5/1243 (20130101) H03B 5/1265 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 11/04 (20130101) H03H 19/006 (20130101) Tuning Resonant Circuits; Selecting Resonant Circuits H03J 2200/10 (20130101) Pulse Technique H03K 3/354 (20130101) H03K 5/04 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/10 (20130101) H03L 7/18 (20130101) H03L 7/093 (20130101) H03L 7/099 (20130101) H03L 7/199 (20130101) H03L 7/0898 (20130101) H03L 7/0992 (20130101) H03L 2207/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954497 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jianxun Zhu (New York, New York); Peter R. Kinget (Summit, New Jersey); Harish Krishnaswamy (New York, New York) |
| ABSTRACT | Circuits for low noise amplifiers with interferer reflecting loops are provided. In some embodiments, circuits for a low noise amplifier with an interferer reflecting loop are provided, the circuits comprising: a low noise amplifier (LNA) having an input and an output; a buffer having an input coupled to the output of the LNA and an output; and notch filter having an input coupled to the output of the buffer and an output coupled to the input of the LNA. |
| FILED | Monday, February 09, 2015 |
| APPL NO | 15/117662 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 1/223 (20130101) H03F 1/342 (20130101) Original (OR) Class H03F 3/72 (20130101) H03F 3/193 (20130101) H03F 3/211 (20130101) H03F 3/45179 (20130101) H03F 3/45645 (20130101) H03F 2200/06 (20130101) H03F 2200/09 (20130101) H03F 2200/78 (20130101) H03F 2200/168 (20130101) H03F 2200/294 (20130101) H03F 2200/411 (20130101) H03F 2203/45311 (20130101) H03F 2203/45418 (20130101) H03F 2203/45424 (20130101) H03F 2203/45512 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954512 | Rinaldi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Matteo Rinaldi (Boston, Massachusetts); Zhenyun Qian (Boston, Massachusetts); Yu Hui (Billerica, Massachusetts) |
| ABSTRACT | A resonator including a piezoelectric plate and an interdigital electrode is provided. A ratio between a thickness of the plate and a pitch of the interdigital electrode may be from about 0.5 to about 1.5. A radiation detector including a resonator and an absorber layer capable of absorbing at least one of infrared and terahertz radiation is provided. A resonator including a piezoelectric plate and a two-dimensional electrically conductive material is provided. |
| FILED | Tuesday, July 11, 2017 |
| APPL NO | 15/646890 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/44 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/1873 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/02 (20130101) H03H 9/13 (20130101) H03H 9/19 (20130101) H03H 9/02244 (20130101) Original (OR) Class H03H 2003/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954527 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | John Michael Wilson (Wake Forest, North Carolina); John W. Poulton (Chapel Hill, North Carolina); Matthew Rudolph Fojtik (Raleigh, North Carolina); Carl Thomas Gray (Apex, North Carolina) |
| ABSTRACT | A balanced, charge-recycling repeater link is disclosed. The link includes a first set of segments operating in a first voltage domain and a second set of segments operating in a second voltage domain. The link is configured to transmit a first signal over at least one segment in the first set of segments and at least one other segment in the second set of segments. Each segment of the link includes at least one active circuit element configured to charge or discharge one or more corresponding interconnects within the link and a level shifter configured to shift the level of a signal on a last interconnect of the segment from the first voltage domain to the second voltage domain or the second voltage domain to the first voltage domain. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/869759 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 19/018528 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954561 | Ray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois); HRL LABORATORIES (Malibu, California) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois); HRL LABORATORIES (Malibu, California) |
| INVENTOR(S) | Gary Alan Ray (Issaquah, Washington); Peter Petre (Oak Park, California); Charles E. Martin (Thousand Okas, California); Shankar R. Rao (Agoura Hills, California) |
| ABSTRACT | A method of processing a plurality of time-varying signals received at a sensor communicatively coupled to a signal data processor to identify at least one parameter of at least one of the plurality of time-varying signals is provided. The method includes receiving, at a plurality of blind source separation (BSS) modules of the signal data processor, signals derived from the plurality of time-varying signals, each BSS module of the plurality of BSS modules including a filtering subsystem having a pipelined architecture and a parallelized architecture. The method also includes generating a plurality of blind source separated signals, and transmitting at least one pulse descriptor word (PDW) parameter vector signal to a computing device of the signal data processor. The method further includes identifying the at least one parameter from the at least one PDW parameter vector signal, and outputting the at least one parameter from the signal data processor. |
| FILED | Monday, September 12, 2016 |
| APPL NO | 15/263016 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/0053 (20130101) Original (OR) Class H04B 1/1638 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954574 | Kwon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wichita State University (Wichita, Kansas); The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | Wichita State University (Wichita, Kansas); The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Hyuck M. Kwon (Wichita, Kansas); Jie Yang (Wichita, Kansas); Khanh D. Pham (Albuquerque, New Mexico) |
| ABSTRACT | Fully connected uplink and downlink fully connected relay network systems using pseudo-noise spreading and despreading sequences subjected to maximizing the signal-to-interference-plus-noise ratio. The relay network systems comprise one or more transmitting units, relays, and receiving units connected via a communication network. The transmitting units, relays, and receiving units each may include a computer for performing the methods and steps described herein and transceivers for transmitting and/or receiving signals. The computer encodes and/or decodes communication signals via optimum adaptive PN sequences found by employing Cholesky decompositions and singular value decompositions (SVD). The PN sequences employ channel state information (CSI) to more effectively and more securely computing the optimal sequences. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 15/527151 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/707 (20130101) Original (OR) Class H04B 7/1851 (20130101) Multiplex Communication H04J 13/10 (20130101) H04J 13/0022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954623 | Dailey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VENCORE LABS, INC. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Vencore Labs, Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | James M. Dailey (Basking Ridge, New Jersey); Anjali Agarwal (Basking Ridge, New Jersey); Paul Toliver (Basking Ridge, New Jersey); Nicholas Peters (Basking Ridge, New Jersey) |
| ABSTRACT | Provided are methods and systems for controlling a phase characteristic of entangled photon pairs. The phase characteristic may be a relative phase difference between photons of the entangled photon pair. Also provided are methods and systems for stabilizing distributed interferometers used in quantum communication systems. |
| FILED | Friday, December 04, 2015 |
| APPL NO | 14/959138 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/70 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954897 | Shen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc (Germantown, Maryland) |
| ASSIGNEE(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| INVENTOR(S) | Dan Shen (Germantown, Maryland); Genshe Chen (Germantown, Maryland); Khanh D. Pham (Germantown, Maryland); Erik Blasch (Germantown, Maryland) |
| ABSTRACT | Methods and systems for providing cyber security, wherein a computer with network access incorporates game theory and utilizes a honeypot to enhance game-theoretic developments over active and passive sensors. To numerically solve the uniquely three-sided game modeled cyber security problem, using a geometric solution based on three-dimensional (3D) action surface and action curve. The methods and systems determine whether the game problem has one Nash equilibrium, multiple Nash equilibriums, or no Nash equilibrium; checks whether the equilibrium is a mixed or pure Nash; and timely computes Nash equilibriums; and follows a fictitious play concept. The solution is adaptive and can be applied for any partially observed cyber security system. |
| FILED | Tuesday, March 01, 2016 |
| APPL NO | 15/057234 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1408 (20130101) H04L 63/1491 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09955087 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Zhenqiang Ma (Middleton, Wisconsin); Munho Kim (Champaign, Illinois) |
| ABSTRACT | Photodetectors based on hydrogen-doped, single-crystalline germanium, including waveguide integrated photodetectors for photonic chip applications are provided. Hydrogen doping provides the single-crystalline germanium with increased radiation absorption in the near infrared region of the electromagnetic spectrum, including at wavelengths of 1550 nm and above. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/395905 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) G02B 2006/12061 (20130101) G02B 2006/12138 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0288 (20130101) H01L 31/1808 (20130101) H01L 31/022408 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09955546 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ryan P. Lu (San Diego, California); Aaron J. Lebsack (San Diego, California); Ayax D. Ramirez (Chula Vista, California); Bienvenido Melvin L. Pascoguin (La Mesa, California) |
| ABSTRACT | A color-changing lighting system includes a color temperature meter for determining a color temperature of visible light within an environment. The color-changing lighting system also includes a microprocessor for converting the color temperature of the visible light to red, green, and blue (RGB) values. The color-changing lighting system further includes a light control unit for calibrating a full spectrum color changing light source to output light having the color temperature of the visible light within the environment, according to the RGB values. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 15/379253 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/0848 (20130101) H05B 33/0854 (20130101) H05B 33/0866 (20130101) H05B 33/0872 (20130101) Original (OR) Class H05B 37/0218 (20130101) H05B 37/0272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 09949611 | Gluesenkamp |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Kyle R. Gluesenkamp (Knoxville, Tennessee) |
| ABSTRACT | A washing machine includes a sealed tub for accepting articles to be washed. A liquid circulation circuit sprays a pressurized liquid (e.g. water, detergent, solvent) around the articles to clean them. The liquid circulation circuit is in thermal contact with a hot side of a thermoelectric device. A heat sink is in thermal contact with both a cold side of the thermoelectric device and a heat sink charging circuit. A liquid is successively directed one or more times through the liquid circulation circuit with the thermoelectric device powered on, and then directed one or more times through the heat sink charging circuit with the thermoelectric device powered off. Finally, the liquid is discharged from the tub after having its temperature lowered by heat exchange to the heat sink. |
| FILED | Tuesday, January 31, 2017 |
| APPL NO | 15/420431 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Domestic Washing or Cleaning; Suction Cleaners in General A47L 15/0047 (20130101) A47L 15/4221 (20130101) A47L 15/4223 (20130101) A47L 15/4225 (20130101) A47L 15/4285 (20130101) A47L 15/4291 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/02 (20130101) F25B 30/00 (20130101) F25B 41/046 (20130101) F25B 2321/0212 (20130101) F25B 2321/0252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949927 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ting Xu (Berkeley, California); He Dong (Albany, California); Jessica Shu (San Francisco, California); Nikhil Dube (Berkeley, California) |
| ABSTRACT | The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer blocks. The conjugates can self-assemble to form helix bundle subunits, which in turn assemble to provide micellar nanocarriers for drug cargos and other agents. Particles containing the conjugates and methods for forming the particles are also disclosed. |
| FILED | Thursday, September 18, 2014 |
| APPL NO | 14/490336 |
| ART UNIT | 1676 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/704 (20130101) A61K 31/704 (20130101) A61K 47/42 (20130101) A61K 47/62 (20170801) A61K 47/6907 (20170801) A61K 51/1227 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950305 | Wegeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert S. Wegeng (Richland, Washington); Paul H. Humble (Kennewick, Washington); Shankar Krishnan (Wilsonville, Oregon); Steven D. Leith (Albany, Oregon); Daniel R. Palo (Chisolm, Minnesota); Robert A. Dagle (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Robert S. Wegeng (Richland, Washington); Paul H. Humble (Kennewick, Washington); Shankar Krishnan (Wilsonville, Oregon); Steven D. Leith (Albany, Oregon); Daniel R. Palo (Chisolm, Minnesota); Robert A. Dagle (Richland, Washington) |
| ABSTRACT | A solar thermochemical processing system is disclosed. The system includes a first unit operation for receiving concentrated solar energy. Heat from the solar energy is used to drive the first unit operation. The first unit operation also receives a first set of reactants and produces a first set of products. A second unit operation receives the first set of products from the first unit operation and produces a second set of products. A third unit operation receives heat from the second unit operation to produce a portion of the first set of reactants. |
| FILED | Thursday, July 26, 2012 |
| APPL NO | 13/559127 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/127 (20130101) Original (OR) Class B01J 2219/00006 (20130101) B01J 2219/089 (20130101) B01J 2219/00159 (20130101) B01J 2219/0883 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/48 (20130101) C01B 3/384 (20130101) C01B 2203/061 (20130101) C01B 2203/0233 (20130101) C01B 2203/0283 (20130101) C01B 2203/0445 (20130101) C01B 2203/0855 (20130101) C01B 2203/1288 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/30 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 3/04 (20130101) Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 3/188 (20130101) Methods of Steam Generation; Steam Boilers F22B 1/006 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/07 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0612 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/129 (20151101) Y02P 20/134 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) Y10T 137/8593 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951008 | Schneider et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William F. Schneider (Granger, Indiana); Joan F. Brennecke (Granger, Indiana); Edward J. Maginn (South Bend, Indiana); Elaine Mindrup (Chicago, Illinois); Burcu Gurkan (South Bend, Indiana); Erica Price (Mishawaka, Indiana); Brett Goodrich (Mishawaka, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| INVENTOR(S) | William F. Schneider (Granger, Indiana); Joan F. Brennecke (Granger, Indiana); Edward J. Maginn (South Bend, Indiana); Elaine Mindrup (Chicago, Illinois); Burcu Gurkan (South Bend, Indiana); Erica Price (Mishawaka, Indiana); Brett Goodrich (Mishawaka, Indiana) |
| ABSTRACT | Some embodiments described herein relate to ionic liquids comprising an anion of a heteraromatic compound such as optionally substituted pyrrolide, optionally substituted pyrazolide, optionally substituted indolide, optionally substituted phospholide, or optionally substituted imidazolide. Methods and devices for gas separation or gas absorption related to these ionic liquids are also described herein. |
| FILED | Wednesday, November 03, 2010 |
| APPL NO | 13/505730 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/1456 (20130101) B01D 53/1493 (20130101) B01D 2252/30 (20130101) B01D 2257/302 (20130101) B01D 2257/404 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) Heterocyclic Compounds C07D 207/32 (20130101) Original (OR) Class C07D 207/33 (20130101) C07D 207/34 (20130101) C07D 207/46 (20130101) C07D 207/323 (20130101) C07D 207/325 (20130101) C07D 209/08 (20130101) C07D 231/12 (20130101) C07D 233/58 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/5407 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/326 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/152 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951095 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Hong-Cai Zhou (College Station, Texas); Tian-Fu Liu (College Station, Texas); Xizhen Lian (College Station, Texas); Lanfang Zou (College Station, Texas); Dawei Feng (College Station, Texas) |
| ABSTRACT | The present invention relates to monocrystalline metal organic frameworks comprising chromium ions and carboxylate ligands and the use of the same, for example their use for storing a gas. The invention also relates to methods for preparing metal organic frameworks comprising chromium, titanium or iron ions and carboxylate ligands. The methods of the invention allow such metal organic frameworks to be prepared in monocrystalline or polycrystalline forms. |
| FILED | Monday, May 11, 2015 |
| APPL NO | 15/307267 |
| ART UNIT | 1671 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/28 (20130101) C07F 11/005 (20130101) Original (OR) Class C07F 15/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951291 | Erdemir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Ali Erdemir (Naperville, Illinois); Anil U. Mane (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Giovanni Ramirez (Argonne, Illinois); Osman Eryilmaz (Argonne, Illinois) |
| ABSTRACT | A lubricant composition includes an oil including a plurality of long-chain hydrocarbon molecules. A quantity of a catalytically active metal-organic additive is mixed with the oil. The metal-organic additive is formulated to fragment the long-chain hydrocarbon molecules of the oil into at least one of dimers and trimers under the influence of at least one of a mechanical loading and a thermal loading. In some embodiments, the metal-organic additive includes a compound of formula II: where: X is Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, Hf, Ta, W, Re, Os, Ir, Pt, Au, Hg, Rf, Db, Sg, Bh, Hs, Mt, Ds, Rg or Cn, and R1, R2, R3 and R4 are alkyl or alkyl halide. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 14/720021 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 169/04 (20130101) Original (OR) Class C10M 2201/062 (20130101) C10M 2205/0285 (20130101) C10M 2207/401 (20130101) C10M 2207/2805 (20130101) C10M 2209/1033 (20130101) C10M 2227/09 (20130101) C10M 2227/081 (20130101) C10M 2229/025 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2210/01 (20130101) C10N 2210/02 (20130101) C10N 2210/03 (20130101) C10N 2210/04 (20130101) C10N 2210/05 (20130101) C10N 2210/06 (20130101) C10N 2210/07 (20130101) C10N 2210/08 (20130101) C10N 2230/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951345 | Steen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eric J. Steen (San Francisco, California); Jeffrey L. Fortman (San Francisco, California); Jeffrey A. Dietrich (San Francisco, California); Jay D. Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a method of producing one or more fatty acid derived dicarboxylic acids in a genetically modified host cell which does not naturally produce the one or more derived fatty acid derived dicarboxylic acids. The invention provides for the biosynthesis of dicarboxylic acid ranging in length from C3 to C26. The host cell can be further modified to increase fatty acid production or export of the desired fatty acid derived compound, and/or decrease fatty acid storage or metabolism. |
| FILED | Wednesday, May 22, 2013 |
| APPL NO | 13/900397 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/0077 (20130101) C12N 15/81 (20130101) Original (OR) Class C12N 15/815 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/40 (20130101) C12P 7/46 (20130101) C12P 7/6409 (20130101) Enzymes C12Y 114/15003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951359 | Elkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | James G. Elkins (Knoxville, Tennessee); Sonya Clarkson (Oak Ridge, Tennessee) |
| ABSTRACT | The present invention relates to microorganisms and polypeptides for detoxifying aldehydes associated with industrial fermentations. In particular, a heat-stable, NADPH- and iron-dependent alcohol dehydrogenase was cloned from Thermoanaerobacter pseudethanolicus 39E and displayed activity against a number of aldehydes including inhibitory compounds that are produced during the dilute-acid pretreatment process of lignocellulosic biomass before fermentation to biofuels. Methods to use the microorganisms and polypeptides of the invention for improved conversion of bio mass to biofuel are provided as well as use of the enzyme in metabolic engineering strategies for producing longer-chain alcohols from sugars using thermophilic, fermentative microorganisms. |
| FILED | Thursday, March 03, 2016 |
| APPL NO | 15/060078 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 17/04 (20130101) Original (OR) Class C12P 2201/00 (20130101) Enzymes C12Y 101/01002 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951397 | Roth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | John Roth (Mckean, Pennsylvania); Jian Cao (Wilmette, Illinois) |
| ABSTRACT | A process and apparatus for forming a sheet metal component using an electric current passing through the component. The process can include providing an incremental forming machine, the machine having at least one arcuate tipped tool and at least electrode spaced a predetermined distance from the arcuate tipped tool. The machine is operable to perform a plurality of incremental deformations on the sheet metal component using the arcuate tipped tool. The machine is also operable to apply an electric direct current through the electrode into the sheet metal component at the predetermined distance from the arcuate tipped tool while the machine is forming the sheet metal component. |
| FILED | Monday, June 02, 2014 |
| APPL NO | 14/293270 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 31/005 (20130101) B21D 37/16 (20130101) Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 1/06 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/09 (20130101) C21D 1/40 (20130101) C21D 7/02 (20130101) Original (OR) Class C21D 7/13 (20130101) C21D 9/0018 (20130101) C21D 9/46 (20130101) C21D 9/48 (20130101) C21D 9/0068 (20130101) C21D 2261/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951398 | Auxier, II et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | John D. Auxier, II (Knoxville, Tennessee); Daniel Hanson (Aiken, South Carolina); Matthew L. Marsh (Knoxville, Tennessee); Howard L. Hall (Knoxville, Tennessee) |
| ABSTRACT | Methods are provided for characterizing samples containing chemical elements such as rare earth elements, actinides, and heavy transition metals by treating the samples to form volatile complexes of the elements (e.g., β-diketonate complexes or other organic ligand complexes of the elements) and then analyzing the complexes, for example, via gas-phase thermochromatography. Also provided are methods for separating and/or recovering such chemical elements. The methods produce less waste and can be performed more rapidly than conventional liquid extraction methods and can provide separated elements of high purity (e.g., 99.9999% purity). |
| FILED | Thursday, July 23, 2015 |
| APPL NO | 14/807463 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 7/007 (20130101) C22B 59/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/12 (20130101) G01N 2030/025 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/02 (20130101) G21F 9/04 (20130101) G21F 9/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951399 | Fassbender et al. |
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| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Michael E. Fassbender (Los Alamos, New Mexico); Valery Radchenko (Los Alamos, New Mexico) |
| ABSTRACT | Protactinium, actinium, radium, radiolanthanides and other radionuclide fission products were separated and recovered from a proton-irradiated thorium target. The target was dissolved in concentrated HCl, which formed anionic complexes of protactinium but not with thorium, actinium, radium, or radiolanthanides. Protactinium was separated from soluble thorium by loading a concentrated HCl solution of the target onto a column of strongly basic anion exchanger resin and eluting with concentrated HCl. Actinium, radium and radiolanthanides elute with thorium. The protactinium that is retained on the column, along with other radionuclides, is eluted may subsequently treated to remove radionuclide impurities to afford a fraction of substantially pure protactinium. The eluate with the soluble thorium, actinium, radium and radiolanthanides may be subjected to treatment with citric acid to form anionic thorium, loaded onto a cationic exchanger resin, and eluted. Actinium, radium and radiolanthanides that are retained can be subjected to extraction chromatography to separate the actinium from the radium and from the radio lanthanides. |
| FILED | Wednesday, April 08, 2015 |
| APPL NO | 14/681320 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 7/006 (20130101) C22B 60/026 (20130101) C22B 60/0295 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/234 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951431 | Jackson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | James E. Jackson (Haslett, Michigan); Chun Ho Lam (East Lansing, Michigan); Christopher M. Saffron (Okemos, Michigan); Dennis J. Miller (Okemos, Michigan) |
| ABSTRACT | A process and related electrode composition are disclosed for the electrocatalytic hydrogenation and/or hydrodeoxygenation of organic substrates such as biomass-derived bio-oil components by the production of hydrogen atoms on a catalyst surface followed by the reaction of the hydrogen atoms with the organic reactants. Biomass fast pyrolysis-derived bio-oil is a liquid mixture containing hundreds of organic compounds with chemical functionalities that are corrosive to container materials and are prone to polymerization. A high surface area skeletal metal catalyst material such as Raney Nickel can be used as the cathode. Electrocatalytic hydrogenation and/or hydrodeoxygenation convert the organic substrates under mild conditions to reduce coke formation and catalyst deactivation. The process converts oxygen-containing functionalities and unsaturated bonds into chemically reduced forms with an increased hydrogen content. The process is operated at mild conditions, which enables it to be a good means for stabilizing bio-oil to a form that can be stored and transported using metal containers and pipes. |
| FILED | Wednesday, October 23, 2013 |
| APPL NO | 14/061460 |
| ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) Original (OR) Class C25B 9/00 (20130101) C25B 11/0415 (20130101) C25B 11/0442 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951976 | Moghaddam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Saeed Moghaddam (Gainesville, Florida); Devesh Chugh (Gainesville, Florida) |
| ABSTRACT | An absorption based heater is constructed on a fluid barrier heat exchanging plate such that it requires little space in a structure. The absorption based heater has a desorber, heat exchanger, and absorber sequentially placed on the fluid barrier heat exchanging plate. The vapor exchange faces of the desorber and the absorber are covered by a vapor permeable membrane that is permeable to a refrigerant vapor but impermeable to an absorbent. A process fluid flows on the side of the fluid barrier heat exchanging plate opposite the vapor exchange face through the absorber and subsequently through the heat exchanger. The absorption based heater can include a second plate with a condenser situated parallel to the fluid barrier heat exchanging plate and opposing the desorber for condensation of the refrigerant for additional heating of the process fluid. |
| FILED | Tuesday, June 02, 2015 |
| APPL NO | 15/316246 |
| ART UNIT | 3744 — Material and Article Handling |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 15/00 (20130101) F25B 15/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952144 | Alexander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | M. Lizabeth Alexander (Richland, Washington); James F. Kelly (Pasco, Washington); Robert L. Sams (Kennewick, Washington); James J. Moran (Richland, Washington); Matthew K. Newburn (West Richland, Washington); Thomas A. Blake (Kennewick, Washington) |
| ABSTRACT | A capillary absorption spectrometer and process are described that provide highly sensitive and accurate stable absorption measurements of analytes in a sample gas that may include isotopologues of carbon and oxygen obtained from gas and biological samples. It further provides isotopic images of microbial communities that allow tracking of nutrients at the single cell level. It further targets naturally occurring variations in carbon and oxygen isotopes that avoids need for expensive isotopically labeled mixtures which allows study of samples taken from the field without modification. The process also permits sampling in vivo permitting real-time ambient studies of microbial communities. |
| FILED | Wednesday, February 17, 2016 |
| APPL NO | 15/046082 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/4338 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/59 (20130101) G01N 21/718 (20130101) G01N 21/3103 (20130101) G01N 21/3504 (20130101) Original (OR) Class G01N 2021/052 (20130101) G01N 2021/0346 (20130101) G01N 2021/399 (20130101) G01N 2021/3125 (20130101) G01N 2021/8578 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02328 (20130101) G02B 6/4296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952216 | Visel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Axel Visel (El Cerrito, California); John L. R. Rubenstein (San Francisco, California); Ying-Jiun (Jasmine) Chen (South San Francisco, California); Len A. Pennacchio (Sebastopol, California); Daniel Vogt (Burlingame, California); Cory Nicholas (San Francisco, California); Arnold Kriegstein (Mill Valley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Axel Visel (El Cerrito, California); John L. R. Rubenstein (San Francisco, California); Ying-Jiun (Jasmine) Chen (South San Francisco, California); Len A. Pennacchio (Sebastopol, California); Daniel Vogt (Burlingame, California); Cory Nicholas (San Francisco, California); Arnold Kriegstein (Mill Valley, California) |
| ABSTRACT | Herein are described a set of novel specific human enhancers for specific forebrain cell types used to study and select for human neural progenitor cells. This approach enables the ability to generate interneurons from human ES, iPS and iN cells, making them available for human transplantation and for molecular/cellular analyzes. These approaches are also directly applicable to generating other neuronal cell types, such as cortical and striatal projection neurons, which have implications for many human diseases. |
| FILED | Friday, October 10, 2014 |
| APPL NO | 14/512306 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2830/008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/56966 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952254 | Briggs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, Minnesota) |
| INVENTOR(S) | Timothy Briggs (Brentwood, California); Bryan Loyola (San Jose, California) |
| ABSTRACT | Various technologies to facilitate coupled electrical and mechanical measurement of conductive materials are disclosed herein. A gripping device simultaneously holds a specimen in place and causes contact to be made between the specimen and a plurality of electrodes connected to an electrical measuring device. An electrical characteristic of the specimen is then measured while a mechanical load is applied to the specimen, and a relationship between the mechanical load and changes in the electrical characteristic can be identified. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/940009 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/0416 (20130101) Original (OR) Class G01R 31/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952331 | Fischbach |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Ephraim Fischbach (West Lafayette, Indiana) |
| ABSTRACT | An apparatus for detecting the presence of a nuclear reactor by the detection of antineutrinos from the reactor can include a radioactive sample having a measurable nuclear activity level and a decay rate capable of changing in response to the presence of antineutrinos, and a detector associated with the radioactive sample. The detector is responsive to at least one of a particle or radiation formed by decay of the radioactive sample. A processor associated with the detector can correlate rate of decay of the radioactive sample to a flux of the antineutrinos to detect the reactor. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 14/866300 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/20 (20130101) G01T 1/1606 (20130101) Original (OR) Class G01T 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954222 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BASF Corporation (Florham Park, New Jersey) |
| ASSIGNEE(S) | BASF Corporation (Florham Park, New Jersey) |
| INVENTOR(S) | Kwo Young (Troy, Michigan); Jean Nei (Southgate, Michigan) |
| ABSTRACT | Heterogeneous metal hydride (MH) compositions comprising a main region comprising a first metal hydride and a secondary region comprising one or more additional components selected from the group consisting of second metal hydrides, metals, metal alloys and further metal compounds are suitable as anode materials for lithium ion cells. The first metal hydride is for example MgH2. Methods for preparing the composition include coating, mechanical grinding, sintering, heat treatment and quenching techniques. |
| FILED | Wednesday, April 22, 2015 |
| APPL NO | 14/693296 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 4/362 (20130101) H01M 4/364 (20130101) H01M 4/366 (20130101) H01M 4/383 (20130101) Original (OR) Class H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954229 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jie Xiao (Richland, Washington); Jun Liu (Richland, Washington); Huilin Pan (Richland, Washington); Wesley A. Henderson (Richland, Washington) |
| ABSTRACT | A device comprising: a lithium sulfur redox flow battery comprising an electrolyte composition comprising: (i) a dissolved Li2Sx electroactive salt, wherein x≥4; (ii) a solvent selected from dimethyl sulfoxide, tetrahydrofuran, or a mixture thereof; and (iii) a supporting salt at a concentration of at least 2 M, as measured by moles of supporting salt divided by the volume of the solvent without considering the volume change of the electrolyte after dissolving the supporting salt. |
| FILED | Friday, October 31, 2014 |
| APPL NO | 14/530442 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/663 (20130101) Original (OR) Class H01M 8/20 (20130101) H01M 12/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954362 | Low et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Steven H. Low (La Canada, Canada); Qiuyu Peng (Pasadena, California) |
| ABSTRACT | Node controllers and power distribution networks in accordance with embodiments of the invention enable distributed power control. One embodiment includes a node controller including a distributed power control application; a plurality of node operating parameters describing the operating parameter of a node and a set of at least one node selected from the group consisting of an ancestor node and at least one child node; wherein send node operating parameters to nodes in the set of at least one node; receive operating parameters from the nodes in the set of at least one node; calculate a plurality of updated node operating parameters using an iterative process to determine the updated node operating parameters using the node operating parameters that describe the operating parameters of the node and the set of at least one node, where the iterative process involves evaluation of a closed form solution; and adjust node operating parameters. |
| FILED | Tuesday, May 26, 2015 |
| APPL NO | 14/722075 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/00 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 12/6418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954527 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | John Michael Wilson (Wake Forest, North Carolina); John W. Poulton (Chapel Hill, North Carolina); Matthew Rudolph Fojtik (Raleigh, North Carolina); Carl Thomas Gray (Apex, North Carolina) |
| ABSTRACT | A balanced, charge-recycling repeater link is disclosed. The link includes a first set of segments operating in a first voltage domain and a second set of segments operating in a second voltage domain. The link is configured to transmit a first signal over at least one segment in the first set of segments and at least one other segment in the second set of segments. Each segment of the link includes at least one active circuit element configured to charge or discharge one or more corresponding interconnects within the link and a level shifter configured to shift the level of a signal on a last interconnect of the segment from the first voltage domain to the second voltage domain or the second voltage domain to the first voltage domain. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/869759 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 19/018528 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954760 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dong Chen (Croton on Hudson, New York); Noel A. Eisley (Yorktown Heights, New York); Philip Heidelberger (Cortlandt Manor, New York) |
| ABSTRACT | A method, system and computer program product are disclosed for routing data packet in a computing system comprising a multidimensional torus compute node network including a multitude of compute nodes, and an I/O node network including a plurality of I/O nodes. In one embodiment, the method comprises assigning to each of the data packets a destination address identifying one of the compute nodes; providing each of the data packets with a toio value; routing the data packets through the compute node network to the destination addresses of the data packets; and when each of the data packets reaches the destination address assigned to said each data packet, routing said each data packet to one of the I/O nodes if the toio value of said each data packet is a specified value. In one embodiment, each of the data packets is also provided with an ioreturn value used to route the data packets through the compute node network. |
| FILED | Tuesday, January 31, 2017 |
| APPL NO | 15/420588 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 15/17387 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 45/00 (20130101) Original (OR) Class H04L 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09955571 | Hatch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Jonathan Douglas Hatch (Cleveland, Missouri); Stephen McGarry Hatch (Blue Springs, Missouri) |
| ABSTRACT | A PCB page blank includes a flexible substrate, a curable adhesive, a conductive layer, and a conductive layer support. The flexible substrate receives an opaque negative circuit pattern thereon. Portions of the curable adhesive not obscured by the circuit pattern may bond to portions of the conductive layer when exposed to light. The bonded portions of the conductive layer shear or tear from non-bonded portions of the conductive layer such that the bonded portions remain with the flexible substrate and the non-bonded portions remain with the conductive layer support when the flexible substrate and the conductive layer support are separated. The flexible substrate and the bonded portions of the conductive layer thus form a PCB prototype with the bonded portions of the conductive layer forming circuit traces of the circuit pattern. |
| FILED | Monday, September 11, 2017 |
| APPL NO | 15/700433 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/028 (20130101) H05K 1/115 (20130101) H05K 1/144 (20130101) H05K 1/0306 (20130101) Original (OR) Class H05K 3/0023 (20130101) H05K 3/0064 (20130101) H05K 3/103 (20130101) H05K 3/125 (20130101) H05K 3/386 (20130101) H05K 3/4611 (20130101) H05K 3/4644 (20130101) H05K 2201/05 (20130101) H05K 2201/09009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 09949693 | Sereno et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anne Bibiana Sereno (Pearland, Texas) |
| ASSIGNEE(S) | CogNeuro Solutions, LLC (Pearland, Texas) |
| INVENTOR(S) | Anne Bibiana Sereno (Pearland, Texas); Saumil S. Patel (Houston, Texas); Yujan Shrestha (Houston, Texas); Stuart Douglass Red (Houston, Texas) |
| ABSTRACT | Portable operatively simple touch screen apparatus uses testing methods and systems that are free of age and language constraints include special signal processing techniques that provide a temporal resolution highly sensitive for probing cognitive function. The embodiments include or make use of one or more modules implemented at least partially in a set of instructions in software and configured to measure user reaction times to visual stimulus on a touch screen device having a capacitive sensor touch-sensitive surface and a detector of audio waves resulting from touch on the touch-sensitive surface. The modules employ recordation of acoustic vibrations resulting from a user's touching a target location on the touch screen surface spaced from a touched starting location on that surface, in one embodiment, to measure temporal response to a visual stimulus placed at the target location. |
| FILED | Tuesday, July 18, 2017 |
| APPL NO | 15/652347 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/162 (20130101) A61B 5/6898 (20130101) Original (OR) Class A61B 5/7475 (20130101) A61B 2560/0487 (20130101) A61B 2562/0204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09949950 | Benoit et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | Danielle Benoit (Rochester, New York); J. Edward Puzas (Pittsford, New York); Maureen Newman (Rochester, New York); Tzong-Jen Sheu (Rochester, New York) |
| ABSTRACT | The present invention provides compositions and methods for providing controllable local delivery of a therapeutic agent to promote bone formation. In certain embodiments, the invention is used as a treatment for a subject with osteoporosis, bone cancer or bone fracture. The invention provides a therapeutic agent that is tethered to a polymer to form a therapeutic-tethered macromer, where the therapeutic agent is controllably released from the conjugate by degradation of the tether. In certain embodiments, the therapeutic agent is an inhibitor of GSK3β. In certain embodiments, the composition of the invention is specifically targeted to a site in need of bone formation. |
| FILED | Monday, September 14, 2015 |
| APPL NO | 14/853772 |
| ART UNIT | 1676 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class A61K 47/48176 (20130101) A61K 47/48246 (20130101) A61K 47/48869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950007 | Self et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | William T. Self (Oviedo, Florida); Ella Bossy-Wetzel (Winter Park, Florida); Sudipta Seal (Orlando, Florida); Janet Dowding (Winter Garden, Florida) |
| ABSTRACT | A method of treating a subject with elevated levels of peroxynitrite includes administering a therapeutically effective amount of cerium oxide nanoparticles to the subject, wherein the cerium oxide nanoparticles reduce the level of peroxynitrite in the subject. |
| FILED | Monday, June 08, 2015 |
| APPL NO | 14/733185 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950096 | Guelcher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Scott A. Guelcher (Franklin, Tennessee); Edna Margarita Prieto (Nashville, Tennessee); Jerald E. Dumas (Atlanta, Georgia); Katarzyna Jadwiga Zienkiewicz (Nashville, Tennessee); Jonathan Page (Mount Juliet, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Scott A. Guelcher (Franklin, Tennessee); Edna Margarita Prieto (Nashville, Tennessee); Jerald E. Dumas (Atlanta, Georgia); Katarzyna Jadwiga Zienkiewicz (Nashville, Tennessee); Jonathan Page (Mount Juliet, Tennessee) |
| ABSTRACT | The present invention encompasses the finding that certain treatments (e.g., surface modifications) to particulate materials can provide surprising and unexpected benefits and/or features to composites and/or compositions as described herein. In some embodiments, such benefits and/or features may render particular composites and/or compositions particularly useful in a certain therapeutic context (e.g, for repair of tibial plateau, femoral head, craniofacial, or lateral mandibular body defects). The present invention demonstrates that certain composites and/or compositions wherein the particular material is or comprises defatted bone have surprising and beneficial attributes. |
| FILED | Wednesday, January 12, 2011 |
| APPL NO | 13/005528 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/46 (20130101) Original (OR) Class A61L 27/48 (20130101) A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/446 (20130101) A61L 2300/406 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950977 | Krishna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Vijay Krishna (Cleveland Heights, Ohio); Brij M. Moudgil (Gainesville, Florida); Benjamin L. Koopman (Gainesville, Florida) |
| ABSTRACT | Polyhydroxyfullerenes (PHFs) having enhanced electron scavenging capabilities have a ratio of non-hydroxyl functional groups to hydroxyl functional groups that is less than or equal to 0.3. When combined with a semiconductor photocatalyst, such as titanium dioxide nanoparticles, the PHFs provide a photocatalyst for degradation of chemical and biological contaminates with an efficiency of at least twice that of titanium dioxide nanoparticles free of PHFs. The PHFs are included in these catalysts at a weight ratio to titanium dioxide of about 0.001 to about 0.003, whereas significantly lower and higher ratios do not achieve the highly improved photodegradation capability. PHFs outside of the desired structure are shown to be of little value for photodegradation, and can be inhibiting to the photocatalytic activity of TiO2. The enhanced electron scavenging PHFs can be employed as a component of materials for solar cells, field effect transistors, and radical scavengers. |
| FILED | Monday, June 22, 2015 |
| APPL NO | 14/745808 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) B01J 23/06 (20130101) B01J 35/004 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/15 (20170801) C01B 32/152 (20170801) Acyclic or Carbocyclic Compounds C07C 39/17 (20130101) Original (OR) Class C07C 2604/00 (20170501) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0047 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951097 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (La Jolla, California) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wei Zhu (Urbana, Illinois); Steffen Lindert (San Diego, California); Yonghui Zhang (Beijing, China PRC); William Sinko (La Jolla, California); Kai Li (Urbana, Illinois); James Andrew McCammon (La Jolla, California); Eric Oldfield (Champaign, Illinois) |
| ABSTRACT | With the rise in resistance to antibiotics such as methicillin, there is a need for new drugs. The invention provides small molecules that inhibit cellular drug targets such as UPPS and FPPS by interacting with binding pockets, thereby preventing enzyme function. Compounds described herein are also active against Staphylococcus aureus (MIC90˜0.25 μg/mL), can potently synergize with methicillin (fractional inhibitory concentration index=0.25), and are protective in a mouse infection model. The invention therefore provides numerous compounds for anti-bacterial treatments and for restoring sensitivity to drugs such as methicillin, using combination therapies. |
| FILED | Wednesday, December 04, 2013 |
| APPL NO | 14/649153 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/167 (20130101) A61K 31/506 (20130101) A61K 31/551 (20130101) A61K 31/4178 (20130101) A61K 31/4439 (20130101) A61K 31/7034 (20130101) A61K 31/7056 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 233/24 (20130101) C07D 239/06 (20130101) C07D 239/28 (20130101) C07D 243/04 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/26 (20130101) Original (OR) Class C07H 15/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951107 | Rome et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Regets of the University of California (Oakland, California); The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Leonard H. Rome (Los Angeles, California); Valerie A. Kickhoefer (Sherman Oaks, California); Glen Nemerow (La Jolla, California); Cheng-Yu Lai (La Jolla, California); Christopher Wiethoff (Downers Grove, Illinois); Mu Han (Los Angeles, California) |
| ABSTRACT | The invention relates to compositions of vault complexes containing recombinant membrane lytic proteins, such as an adenovirus protein VI lytic domain, and methods of using the vault complexes to facilitate delivery and entry of a biomolecule into a cell or subject. |
| FILED | Thursday, September 24, 2015 |
| APPL NO | 14/863750 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/435 (20130101) C07K 14/485 (20130101) C07K 2319/00 (20130101) C07K 2319/70 (20130101) C07K 2319/75 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1077 (20130101) C12N 15/87 (20130101) C12N 15/88 (20130101) C12N 2710/10322 (20130101) Enzymes C12Y 204/0203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951384 | Schnable et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Data2Bio (Ames, Iowa) |
| ASSIGNEE(S) | DATA2BIO (Ames, Iowa) |
| INVENTOR(S) | Patrick S. Schnable (Ames, Iowa); Sanzhen Liu (Ames, Iowa); Wei Wu (Johnston, Iowa) |
| ABSTRACT | Provided herein is technology relating to genotyping and particularly, but not exclusively, to methods for genotyping one or more organisms by genome sequencing. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 14/723678 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/683 (20130101) C12Q 1/683 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2537/159 (20130101) C12Q 2537/159 (20130101) C12Q 2565/514 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951444 | Dzenis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Yuris Dzenis (Lincoln, Nebraska) |
| ABSTRACT | A method of fabricating a continuous nanofiber is described. The method includes preparing a solution of one or more polymers and one or more solvents and electrospinning the solution by discharging the solution through one or more liquid jets into an electric field to yield one or more continuous nanofibers. The electrospinning process (i) highly orients one or more polymer chains in the one or more continuous nanofibers along a fiber axis of the one or more continuous nanofibers, and (ii) suppresses polymer crystallization in the one or more continuous nanofibers. The one or more continuous nanofibers can have diameters below about 250 nanometers and exhibit an increase in fiber strength and modulus while maintaining strain at failure, resulting in an increase in fiber toughness. |
| FILED | Thursday, December 12, 2013 |
| APPL NO | 14/104930 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) D01D 5/003 (20130101) D01D 5/0038 (20130101) D01D 5/0046 (20130101) D01D 5/0092 (20130101) D01D 10/02 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/02 (20130101) D01F 6/18 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/298 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952031 | Hannigan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Corporation for Atmospheric Research (Boulder, Colorado) |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado) |
| INVENTOR(S) | James Hannigan (Boulder, Colorado); William Mankin (Boulder, Colorado) |
| ABSTRACT | An interferometer (10) is provided that has a stage (28) configured to have a linear motion path. A first retroreflector (18) and a second retroreflector (24) are fixedly coupled to the stage (28). A tube (32) is provided, and the stage (28) is configured to reciprocate about the tube (32). A beamsplitter (14) and a 45° mirror (16) are disposed in the tube (32). A detector (22) is configured to detect light passing through the beamsplitter (14), and the beamsplitter (14) is configured to split an incident light beam into a transmitted beam (15) and a reflected beam (17), wherein the transmitted beam (15) passes to the second retroreflector (24) and the reflected beam (17) passes to the first retroreflector (18). The transmitted beam (15) and a reflected beam (17) are focused on the detector (22). |
| FILED | Wednesday, October 26, 2016 |
| APPL NO | 15/334533 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02015 (20130101) Original (OR) Class G01B 9/02043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952096 | Kats et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Mikhail A. Kats (Cambridge, Massachusetts); Romain Blanchard (Cambridge, Massachusetts); Patrice Genevet (Cambridge, Massachusetts); Federico Capasso (Cambridge, Massachusetts) |
| ABSTRACT | A spectral encoder includes a thin layer of lossy dielectric material whose thickness varies transversely from 0 to a thickness of about λ/4n (e.g., <100 nm), where λ is the wavelength of incident radiation and n is the dielectric material's refractive index. The dielectric layer reflects (and/or transmits) light at a wavelength that depends on the layer's thickness. Because the dielectric layer's thickness varies, different parts of the dielectric layer may reflect (transmit) light at different wavelengths. For instance, shining white light on a dielectric layer with a linearly varying thickness may produce a rainbow-like reflected (and/or transmitted) beam. Thus, the spectral encoder maps different wavelengths to different points in space. This mapping can be characterized by a transfer matrix which can be used to determine the spectrum of radiation incident on the spectral encoder from the spatial intensity distribution of the radiation reflected (and/or transmitted) by the spectral encoder. |
| FILED | Monday, June 03, 2013 |
| APPL NO | 14/404834 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/021 (20130101) G01J 3/26 (20130101) G01J 3/0205 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 3/0218 (20130101) G01J 3/2803 (20130101) G01J 2003/1213 (20130101) Optical Elements, Systems, or Apparatus G02B 5/22 (20130101) G02B 5/207 (20130101) G02B 5/223 (20130101) G02B 5/286 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02162 (20130101) H01L 31/02168 (20130101) H01L 31/02325 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952148 | Georgakoudi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Irene Georgakoudi (Acton, Massachusetts); Sharad Gupta (Medford, Massachusetts); Martin Hunter (Bradford, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Boston, Massachusetts) |
| INVENTOR(S) | Irene Georgakoudi (Acton, Massachusetts); Sharad Gupta (Medford, Massachusetts); Martin Hunter (Bradford, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
| ABSTRACT | In one aspect, the present invention generally provides methods for characterizing mineralization of a material, e.g., a biomaterial, by illuminating the material with radiation and analyzing radiation scattered from the material in response to the illumination. For example, in some embodiments, a material can be illuminated with polarized radiation at a plurality of wavelengths and the elastically scattered radiation corresponding to two or more of those wavelengths can be collected at two polarizations: one parallel and the other perpendicular to the illumination polarization. A differential intensity of the scattered radiation at the two polarizations can be analyzed as a function of wavelength to obtain information regarding the morphology of mineral deposits in the sample. Further, the total scattered radiation can be analyzed to derive information regarding the level of mineralization. |
| FILED | Thursday, February 19, 2009 |
| APPL NO | 12/867383 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/47 (20130101) Original (OR) Class G01N 2021/4792 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952227 | Gruber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York); John B. Pierce Laboratory (New Haven, Connecticut) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York); John B. Pierce Laboratory (New Haven, Connecticut) |
| INVENTOR(S) | David F. Gruber (Fair Lawn, New Jersey); Jean P. Gaffney (Union, New Jersey); Vincent A. Pieribone (Madison, Connecticut) |
| ABSTRACT | Fluorescent proteins (Chlopsid FP I from Kaupichthys hyoproroides and Chlopsid FP II from Kaupichthys n. sp.) are used in a method for detecting bilirubin. The proteins are based on transcriptome analysis of the false moray eels, Kaupichthys hyoproroides and Kaupichthys n. sp., the later representing a heretofore undescribed species. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/348563 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/728 (20130101) Original (OR) Class G01N 2333/43504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952231 | Strongin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Portland State University (Portland, Oregon) |
| ASSIGNEE(S) | Portland State University (Portland, Oregon) |
| INVENTOR(S) | Robert Strongin (Portland, Oregon); Martha Sibrian-Vazquez (Portland, Oregon); Jialu Wang (Portland, Oregon); Lei Wang (Camas, Washington); Jorge O. Escobedo-Cordova (Portland, Oregon) |
| ABSTRACT | Embodiments of methods and compounds for isolating and detecting lysophosphatidic acids (LPAs) are disclosed. Kits for performing the methods also are disclosed. LPAs are isolated from biological samples by liquid-liquid extraction followed by solid phase extraction. LPA species may be separated by HPLC, and the separated species may be identified and quantified. Also disclosed are embodiments of compounds capable of universally detecting a plurality of LPA species with substantially equivalent sensitivity. Embodiments of the disclosed compounds are useful for determination of total LPA concentration in a sample comprising a plurality of LPA species without separation of individual LPA species. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776273 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 491/22 (20130101) C07D 491/107 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952557 | Shaltout et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Amr Shaltout (West Lafayette, Indiana); Sajid Choudhury (West Lafayette, Indiana); Alexander V. Kildishev (West Lafayette, Indiana); Alexandra Boltasseva (West Lafayette, Indiana); Vladimir M. Shalaev (West Lafayette, Indiana) |
| ABSTRACT | A device for producing a subwavelength hologram. The device comprises a metasurface layer attached to a substrate. The metasurface layer includes an array of plasmonic antennas that simultaneously encode both wavelength and phase information of light directed through the array to produce a hologram. The wavelength is determined by the size of the antennas, and the phase is determined by the orientation of the antennas. |
| FILED | Wednesday, May 11, 2016 |
| APPL NO | 15/152535 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/00 (20130101) G02B 1/002 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/00 (20130101) G02F 1/01 (20130101) Holographic Processes or Apparatus G03H 1/02 (20130101) Original (OR) Class G03H 1/024 (20130101) G03H 1/0244 (20130101) G03H 2001/026 (20130101) G03H 2001/2263 (20130101) G03H 2240/11 (20130101) G03H 2240/21 (20130101) Antennas, i.e Radio Aerials H01Q 15/0006 (20130101) H01Q 15/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952870 | Lipasti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mikko Lipasti (Lake Mills, Wisconsin); Dibakar Gope (Madison, Wisconsin) |
| ABSTRACT | An apparatus and method for filtering biased conditional branches in a branch predictor in favor of non-biased conditional branches are disclosed. Biased conditional branches, which are consistently skewed toward one direction or outcome, are filtered such that an increased number of non-biased conditional branches which resolve in both directions may be considered. As a result, more useful branches may be captured over larger distances, thereby providing correlations deeper in a global history. In addition, by tracking only the latest occurrences of non-biased conditional branches using a recency stack structure, even more distant branch correlations may be made. |
| FILED | Friday, June 13, 2014 |
| APPL NO | 14/303932 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3806 (20130101) Original (OR) Class G06F 9/3844 (20130101) G06F 9/3848 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954362 | Low et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Steven H. Low (La Canada, Canada); Qiuyu Peng (Pasadena, California) |
| ABSTRACT | Node controllers and power distribution networks in accordance with embodiments of the invention enable distributed power control. One embodiment includes a node controller including a distributed power control application; a plurality of node operating parameters describing the operating parameter of a node and a set of at least one node selected from the group consisting of an ancestor node and at least one child node; wherein send node operating parameters to nodes in the set of at least one node; receive operating parameters from the nodes in the set of at least one node; calculate a plurality of updated node operating parameters using an iterative process to determine the updated node operating parameters using the node operating parameters that describe the operating parameters of the node and the set of at least one node, where the iterative process involves evaluation of a closed form solution; and adjust node operating parameters. |
| FILED | Tuesday, May 26, 2015 |
| APPL NO | 14/722075 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/00 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 12/6418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 09949489 | Shatters et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Robert G. Shatters (Stuart, Florida); Gary A. Luzio (, None); John K. Morgan (Port Saint Lucie, Florida) |
| ABSTRACT | Compositions having at least one compound which inhibits the formation of Hemipteran stylet sheaths and/or degrades hemipteran style sheaths that have already been formed, and thus deters or blocks hemipteran insects from feeding on plants, especially agriculturally important plants and methods of use of such compositions are described. Such compositions can be applied onto plants by spraying, dripping, or other methods and/or can be applied to the soil for uptake by the roots. These compositions and methods prevent and/or reduce the transmission of vascular associated diseases (caused by hemipteran vector-borne pathogens) to plants. |
| FILED | Thursday, April 28, 2016 |
| APPL NO | 15/140666 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 31/02 (20130101) A01N 31/08 (20130101) A01N 37/06 (20130101) A01N 37/44 (20130101) A01N 37/44 (20130101) A01N 43/16 (20130101) A01N 43/90 (20130101) A01N 59/16 (20130101) A01N 63/02 (20130101) Original (OR) Class A01N 63/04 (20130101) A01N 65/08 (20130101) A01N 65/40 (20130101) A01N 65/44 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 304/16006 (20130101) C12Y 304/22002 (20130101) C12Y 304/22003 (20130101) C12Y 304/22004 (20130101) C12Y 304/22006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950059 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture. (Washington, District of Columbia) |
| INVENTOR(S) | Qingzhong Yu (Athens, Georgia); Stephen J. Spatz (Athens, Georgia); Laszlo Zsak (Athens, Georgia) |
| ABSTRACT | Recombinant chimeric viruses based on NDV LaSota strain and containing either ILTV gB or gD are produced. Administration of the chimeric viruses to chickens induces an immune response in the animal against both NDV and ILTV. Immunogenic compositions, plasmids, kits and methods are described. |
| FILED | Friday, February 13, 2015 |
| APPL NO | 15/120237 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/17 (20130101) Original (OR) Class A61K 39/245 (20130101) A61K 2039/525 (20130101) A61K 2039/552 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/16034 (20130101) C12N 2760/18034 (20130101) C12N 2760/18043 (20130101) C12N 2760/18121 (20130101) C12N 2760/18134 (20130101) C12N 2760/18143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950986 | Bischoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth M. Bischoff (Peoria, Illinois); Timothy D. Leathers (Peoria, Illinois); Neil P. Price (Peoria, Illinois); Pennapa Manitchotpisit (Dunlap, Illinois) |
| ABSTRACT | Novel compounds, called liamocins from Aureobasidium pullulans, having the general structure in Formula 1 are disclosed. where R1 is either COCH3 or H; and R2 is between two to ten O-linked 3,5-dihydroxydecanoate; and R3 can be a polyol (e.g., L- or D-glycerol, L- or D-threitol, L- or D-erythritol, L- or D-arabitol, L- or D-xylitol, L- or D-lyxitol, L- or D-ribitol, L- or D-allitol, L- or D-altritol, L- or D-mannitol, L- or D-iditol, L- or D-gulitol, L- or D-glucitol (also called sorbitol), L- or D-galactitol (also called dulcitol), and L- or D-talitol), 2-amino-D-mannitol, 2N-acetylamino-D-mannitol, L-rhamnitol, or D-fucitol; except when R3 is D-mannitol, R2 is not 2 nor 3 O-linked 3,5-dihydroxydecanoate chains. These liamocins described above in addition to D-mannitol liamocin A1, D-mannitol liamocin A2, D-mannitol liamocin B1, and D-mannitol liamocin B2, alone or in combination with each other, can be used to kill certain bacteria and to treat certain bacterial infections. |
| FILED | Monday, March 16, 2015 |
| APPL NO | 15/126182 |
| ART UNIT | 1671 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/36 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/191 (20130101) Acyclic or Carbocyclic Compounds C07C 69/003 (20130101) C07C 69/21 (20130101) C07C 69/33 (20130101) C07C 69/675 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) C12P 19/44 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09950994 | Jones |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tappey H. Jones (Staunton, Virginia) |
| ASSIGNEE(S) | VMI Foundation (Lexington, Virginia); The United States of America, as represented by the secretary of agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Tappey H. Jones (Staunton, Virginia) |
| ABSTRACT | Methods and compositions for pest control, and more particularly for control of ants, e.g., of the subfamily Myrmicinae, using tyramides. |
| FILED | Thursday, November 03, 2011 |
| APPL NO | 13/883204 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/18 (20130101) A01N 37/36 (20130101) A01N 37/42 (20130101) Acyclic or Carbocyclic Compounds C07C 233/18 (20130101) C07C 235/08 (20130101) C07C 235/74 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 09951271 | Arnatt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | Christopher Arnatt (Kirkwood, Missouri); John Elliott (Silver Spring, Maryland) |
| ABSTRACT | The present invention relates to a process for making an asymmetric fluorophore. The asymmetric fluorophore is useful as a stain for staining live cells or fixed cell and provides whole-cell staining of such cells. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/294065 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 2211/1029 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 2001/302 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951272 | Kamplain |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAMSUNG RESEARCH AMERICA, INC. (Mountain View, California) |
| ASSIGNEE(S) | SAMSUNG RESEARCH AMERICA, INC. (Mountain View, California) |
| INVENTOR(S) | Justin W. Kamplain (Bartlesville, Oklahoma) |
| ABSTRACT | A method for preparing semiconductor nanocrystals includes reacting one or more semiconductor nanocrystal precursors in a liquid medium in the presence of a boronic compound at a reaction temperature resulting in semiconductor nanocrystals. Semiconductor nanocrystals are also disclosed. |
| FILED | Monday, February 17, 2014 |
| APPL NO | 14/182101 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 17/20 (20130101) C01B 19/002 (20130101) C01B 19/007 (20130101) C01B 25/082 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/84 (20130101) C01P 2004/52 (20130101) C01P 2004/64 (20130101) C01P 2004/80 (20130101) C01P 2004/86 (20130101) C01P 2006/40 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/08 (20130101) Original (OR) Class C09K 11/63 (20130101) C09K 11/70 (20130101) C09K 11/0805 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/005 (20130101) H01L 33/16 (20130101) H01L 33/26 (20130101) H01L 33/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09951406 | Lass et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland); Tony Ying (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARMENT OF THE TREASURY (Washington, District of Columbia) |
| INVENTOR(S) | Eric A. Lass (Montgomery Village, Maryland); Mark R. Stoudt (Germantown, Maryland); Carelyn Campbell (Germantown, Maryland); Tsineng Tony Ying (Silver Spring, Maryland) |
| ABSTRACT | A primary alloy includes: nickel; copper; zinc; an electrical conductivity from 5.2% International Annealed Copper Standard (IACS) to 5.6% IACS measured in accordance with ASTM E1004-09 (2009); and a disordered crystalline phase wherein atoms of the nickel, cooper, and zinc are randomly arranged in the disordered crystalline phase at room temperature in a post-annealed state. A process for making the primary alloy includes heating a secondary alloy to a first temperature that is greater than or equal to an annealing temperature to form an annealing alloy, the secondary alloy including a secondary phase; and quenching, by cooling the annealing alloy from the first temperature to a second temperature that is less than the annealing temperature, under a condition effective to form the primary alloy including the disordered crystalline phase, wherein the disordered crystalline phase is different than the secondary phase of the secondary alloy. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 14/940199 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/02 (20130101) C22C 9/04 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952293 | Gopman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | Daniel B. Gopman (Bethesda, Maryland); Robert D. Shull (Boyds, Maryland) |
| ABSTRACT | A magnetic piezoelectric composite adjusts magnetic anisotropy strength in a bimetallic member and includes: a piezoelectric layer to produce a strain in response to receipt of a strain voltage; and the bimetallic member disposed on the piezoelectric layer, the bimetallic member including: a plurality of metal layers, such that a second metal layer is interposed between a pair of first metal layers, the bimetallic member being ferromagnetic; and a magnetic anisotropy strength that changes in response to receipt of the strain from the piezoelectric layer. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/395454 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/093 (20130101) Original (OR) Class G01R 33/098 (20130101) Static Stores G11C 11/161 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/0986 (20130101) H01L 43/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 09950715 | Lanza di Scalea |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents Of The University Of California (Oakland, California) |
| INVENTOR(S) | Francesco Lanza di Scalea (San Diego, California) |
| ABSTRACT | In some example implementations, there is provided a method. The method may include generating, by an air-coupled transducer, a first ultrasonic guided wave to cause the generated ultrasonic guided wave to propagate into a rail being tested for one or more defects, wherein a frequency of the first ultrasonic guided wave is controlled by at least changing the frequency of a voltage sent to the air-coupled transducer generating the first ultrasonic guided wave; receiving, by a receiver, a second ultrasonic guided wave, wherein the second ultrasonic guided wave is received from the rail; and analyzing a signal representative of the received second ultrasonic guided wave to detect the one or more defects in the rail. Related systems, methods, and articles of manufacture are also provided. |
| FILED | Tuesday, April 02, 2013 |
| APPL NO | 14/389052 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/02 (20130101) Vehicle Brake Control Systems or Parts Thereof; Brake Control Systems or Parts Thereof, in General; Arrangement of Braking Elements on Vehicles in General; Portable Devices for Preventing Unwanted Movement of Vehicles; Vehicle Modifications to Facilitate Cooling of Brakes B60T 17/18 (20130101) Auxiliary Equipment Specially Adapted for Railways, Not Otherwise Provided for B61K 9/00 (20130101) Original (OR) Class B61K 9/10 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 17/00 (20130101) G01B 17/04 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/04 (20130101) G01N 29/12 (20130101) G01N 29/46 (20130101) G01N 29/2462 (20130101) G01N 29/4436 (20130101) G01N 2291/0425 (20130101) G01N 2291/2623 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09952326 | McDonald et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morristown, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | James Arthur McDonald (Minneapolis, Minnesota); Douglas Mark Weed (Forest Lake, Minnesota) |
| ABSTRACT | A ground-based system to reduce the effect of interference, comprising a plurality of reference receivers, wherein the reference receivers are spaced a distance apart such that a single source of interference is unable to substantially interfere with a subset of the plurality of reference receivers, wherein the subset of the plurality of reference receivers includes at least two reference receivers; and a processing module communicatively coupled to the plurality of reference receivers and configured to receive data from each of the plurality of reference receivers, wherein the processing module is further configured to perform differential calculations on the data to calculate measurement corrections and estimated errors. |
| FILED | Thursday, November 06, 2014 |
| APPL NO | 14/535126 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/07 (20130101) Original (OR) Class G01S 19/21 (20130101) G01S 19/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 09954574 | Kwon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wichita State University (Wichita, Kansas); The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | Wichita State University (Wichita, Kansas); The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Hyuck M. Kwon (Wichita, Kansas); Jie Yang (Wichita, Kansas); Khanh D. Pham (Albuquerque, New Mexico) |
| ABSTRACT | Fully connected uplink and downlink fully connected relay network systems using pseudo-noise spreading and despreading sequences subjected to maximizing the signal-to-interference-plus-noise ratio. The relay network systems comprise one or more transmitting units, relays, and receiving units connected via a communication network. The transmitting units, relays, and receiving units each may include a computer for performing the methods and steps described herein and transceivers for transmitting and/or receiving signals. The computer encodes and/or decodes communication signals via optimum adaptive PN sequences found by employing Cholesky decompositions and singular value decompositions (SVD). The PN sequences employ channel state information (CSI) to more effectively and more securely computing the optimal sequences. |
| FILED | Tuesday, November 17, 2015 |
| APPL NO | 15/527151 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/707 (20130101) Original (OR) Class H04B 7/1851 (20130101) Multiplex Communication H04J 13/10 (20130101) H04J 13/0022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09954613 | Goorjian |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Peter M. Goorjian (Oakland, California) |
| ABSTRACT | Light is used to communicate between objects separated by a large distance. Light beams are received in a telescopic lens assembly positioned in front of a cat's-eye lens. The light can thereby be received at various angles to be output by the cat's-eye lens to a focal plane of the cat's-eye lens, the position of the light beams upon the focal plane corresponding to the angle of the beam received. Lasers and photodetectors are distributed along this focal plane. A processor receives signals from the photodetectors, and selectively signal lasers positioned proximate the photodetectors detecting light, in order to transmit light encoding data through the cat's-eye lens and also through a telescopic lens back in the direction of the received light beams, which direction corresponds to a location upon the focal plane of the transmitting lasers. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 15/710478 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/4257 (20130101) Transmission H04B 10/67 (20130101) H04B 10/118 (20130101) H04B 10/1123 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 09951273 | Nick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Gyeonggi-Do, South Korea) |
| INVENTOR(S) | Robert J. Nick (Pepperell, Massachusetts) |
| ABSTRACT | The present invention relates to a formulation comprising a medium, one or more stabilizers, and one or more particles comprising nanoparticles included within a host material. In certain embodiments, a stabilizer comprises a HALS stabilizer. In certain embodiments, a stabilizer comprises a UVA stabilizer. In certain embodiments, the formulation includes a HALS stabilizer and a UVA stabilizer. In certain embodiments, nanoparticles have light-emissive properties. Other embodiments relate to a powder obtainable from a formulation of the invention, a composition including a powder of the invention, a coating comprising a formulation of the invention, and products and applications including a particle of the invention. In preferred embodiments, a nanoparticle comprises a semiconductor nanocrystal. In certain embodiments, a host material comprises a polymer. In certain embodiments, a host material comprises an inorganic material. A raw batch formulation and particle obtainable therefrom is also disclosed. |
| FILED | Monday, April 04, 2016 |
| APPL NO | 15/089764 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/18 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/18 (20130101) C08F 2220/1883 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/3435 (20130101) C08K 5/3492 (20130101) C08K 9/10 (20130101) C08K 13/02 (20130101) C08K 13/02 (20130101) C08K 2201/001 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 33/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/22 (20130101) C09D 5/24 (20130101) C09D 7/1225 (20130101) C09D 7/1241 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/025 (20130101) C09K 11/703 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/83 (20130101) Y10S 977/834 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 09952762 | Jordan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | J. Bern Jordan (Madison, Wisconsin); David P. Kelso (Madison, Wisconsin); Gregg C. Vanderheiden (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | J. Bern Jordan (Madison, Wisconsin); David P. Kelso (Madison, Wisconsin); Gregg C. Vanderheiden (Madison, Wisconsin) |
| ABSTRACT | An interface system that allows for tactile manipulation of a touch screen for people with disabilities and which provides appropriate tactile marking for the action they wish to carry out and that may afford a sensation that a button is being pressed to a user, is provided. The system includes a touch screen and a tactile button assembly that extends over at least a portion of the touch screen. The tactile button assembly includes tactile buttons with tactile indicia that can be felt by a user. The tactile buttons are arranged with respect to the touch screen so that when a tactile button is pressed by a user, a contact end of the tactile button contacts a button on the touch screen to perform a predetermined task associated with pressing such button on the touch screen. |
| FILED | Monday, August 20, 2012 |
| APPL NO | 13/589628 |
| ART UNIT | 2625 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/039 (20130101) G06F 3/04886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 09951221 | Esser-Kahn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Aaron P. Esser-Kahn (Champaign, Illinois); Hefei Dong (Urbana, Illinois); Piyush R. Thakre (Urbana, Illinois); Jason F. Patrick (Urbana, Illinois); Nancy R. Sottos (Champaign, Illinois); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois) |
| ABSTRACT | A thermally degradable polymeric fiber comprising a polymeric fiber matrix including a poly(hydroxyalkanoate) and a metal in the form of a compound selected from the group consisting of an alkaline earth metal oxide, a tin salt of a mono- or di-carboxylic acid, and scandium triflate (Sc(0Tf)3), where the concentration of the metal in the fiber matrix is at least 0.1 wt %. |
| FILED | Tuesday, January 27, 2015 |
| APPL NO | 14/606553 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0007 (20130101) B29C 47/0014 (20130101) B29C 67/202 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/20 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Original (OR) Class Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/06 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/04 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2958 (20150115) Y10T 428/249978 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 09951102 | Miller, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Francis J. Miller, Jr. (Coralville, Iowa); Jennifer Streeter (Iowa City, Iowa) |
| ABSTRACT | An isolated peptide or fusion having the peptide useful to interfere with the phosphorylation of Nox1, block or inhibit binding of NoxA1 activation domain (AD) to Nox1, and/or prevent or inhibit assembly of the p47phox/NoxA1 complex with Nox1, or a vector encoding the peptide or fusion thereof, and methods of using the peptide, fusion or vector are provided. |
| FILED | Friday, April 17, 2015 |
| APPL NO | 14/689803 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class C07K 2319/01 (20130101) C07K 2319/09 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
European Union (EU)
| US 09952325 | Fernandez-Hernandez |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE EUROPEAN UNION, represented by THE EUROPEAN COMMISSION (Brussels, Belgium) |
| ASSIGNEE(S) | THE EUROPEAN UNION, REPRESENTED BY THE EUROPEAN COMMISSION (Brussels, Belgium) |
| INVENTOR(S) | Ignacio Fernandez-Hernandez (Watermael-Boitsfort, Belgium) |
| ABSTRACT | The invention introduces “crossed” navigation message authentication, which comprises a) generation and transmission of unpredictable bits periodically from satellites currently not connected to the ground mission segment and b) generation of digital signatures for the data from these satellites, and the transmission thereof through satellites that currently are connected to the ground mission segment. An attacker cannot spoof the navigation message as it contains an unpredictable bit pattern that is verified a few seconds later through a digital signature. |
| FILED | Friday, July 04, 2014 |
| APPL NO | 14/904287 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/03 (20130101) G01S 19/05 (20130101) Original (OR) Class G01S 19/215 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 09952216 | Visel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Axel Visel (El Cerrito, California); John L. R. Rubenstein (San Francisco, California); Ying-Jiun (Jasmine) Chen (South San Francisco, California); Len A. Pennacchio (Sebastopol, California); Daniel Vogt (Burlingame, California); Cory Nicholas (San Francisco, California); Arnold Kriegstein (Mill Valley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Axel Visel (El Cerrito, California); John L. R. Rubenstein (San Francisco, California); Ying-Jiun (Jasmine) Chen (South San Francisco, California); Len A. Pennacchio (Sebastopol, California); Daniel Vogt (Burlingame, California); Cory Nicholas (San Francisco, California); Arnold Kriegstein (Mill Valley, California) |
| ABSTRACT | Herein are described a set of novel specific human enhancers for specific forebrain cell types used to study and select for human neural progenitor cells. This approach enables the ability to generate interneurons from human ES, iPS and iN cells, making them available for human transplantation and for molecular/cellular analyzes. These approaches are also directly applicable to generating other neuronal cell types, such as cortical and striatal projection neurons, which have implications for many human diseases. |
| FILED | Friday, October 10, 2014 |
| APPL NO | 14/512306 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2830/008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/56966 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 09951069 | Fuller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rodin Therapeutics, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Rodin Therapeutics, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, II (Stonington, Connecticut) |
| ABSTRACT | Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2). |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 15/867982 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 09952313 | Cho |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Seal Beach, California) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Kwang M. Cho (Los Angeles, California) |
| ABSTRACT | A Radar Calibration Processor (“RCP”) for calibrating the phase of a stepped-chirp signal utilized by a synthetic aperture radar (“SAR”) is disclosed. The RCP includes a periodic phase error (“PPE”) calibrator, first non-periodic phase error (“NPPE”) calibrator in signal communication with the PPE calibrator, and a second NPPE calibrator in signal communication with the first NPPE calibrator. |
| FILED | Friday, September 19, 2014 |
| APPL NO | 14/491354 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4004 (20130101) Original (OR) Class G01S 13/30 (20130101) G01S 13/90 (20130101) G01S 13/282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09953080 | Compton |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Ryan F. Compton (Los Angeles, California) |
| ABSTRACT | Described is system for early detection of civil unrest events. A set of textual social media data having corresponding user identifications is received as input. The textual social media data is filtered with a keyword filter, resulting in a first set of data comprising keywords of interest. The first set of data is then filtered with a future date filter, resulting in a second set of data comprising future dates. The second set of data is filtered based on relevance to a civil unrest event with a text classifier module, resulting in a third set of data that is classified based on relevance to the civil unrest event. The third set of data is then filtered based on a location of interest, resulting in a fourth set of data having user identifications in the location of interest. A location is assigned to the civil unrest event, and a forecast of the civil unrest event is output. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/295101 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30699 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 24, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180424.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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