FedInvent™ Patents
Patent Details for Tuesday, May 22, 2018
This page was updated on Monday, March 27, 2023 at 05:32 AM GMT
Department of Health and Human Services (HHS)
US 09974289 | Ebert et al. |
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FUNDED BY |
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APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Benjamin Levine Ebert (Boston, Massachusetts); Jan Krönke (Boston, Massachusetts); Steven A. Carr (Cambridge, Massachusetts); Namrata D. Udeshi (Cambridge, Massachusetts); Emma Fink (Boston, Massachusetts) |
ABSTRACT | The present invention features a knock-in mouse comprising a mutation in an endogenous CRBN locus and methods of use thereof. |
FILED | Friday, March 18, 2016 |
APPL NO | 15/074920 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Original (OR) Class A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/94 (20130101) G01N 33/5011 (20130101) G01N 33/5088 (20130101) G01N 33/57496 (20130101) G01N 2333/47 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974463 | Rutkove et al. |
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APPLICANT(S) | Seward B. Rutkove (Brookline, Massachusetts); Joel L. Dawson (Roslindale, Massachusetts) |
ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Seward B. Rutkove (Brookline, Massachusetts); Joel L. Dawson (Roslindale, Massachusetts) |
ABSTRACT | A device for determining muscle condition of a region of tissue. The device comprises an electrical impedance myography (EIM) portable probe bearing an electrode array. The electrode array comprises excitation electrodes used to apply multi-frequency electrical signals to the region of tissue and pickup electrodes that are used to collect electrical signals resulting from the application of the multi-frequency electrical signals to the region of tissue. To improve accuracy and reproducibility of EIM measurements, the electrode array is reconfigurable to select different subsets of excitation and pickup electrodes so that the electrodes are oriented differently with respect to muscle fibers. Additional devices may be associated with the EIM probe to measure such parameters as temperature, moisture content of the region, quality of contact of electrodes of the electrode array with a surface of the region and pressure with which the EEM probe is applied to the region. The EIM measurements may be adjusted based on these parameters. Also, ultrasound and electrical impedance tomography measurements may supplement the ELM measurements for more complete analysis of the muscle condition. |
FILED | Friday, August 20, 2010 |
APPL NO | 13/391484 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/053 (20130101) Original (OR) Class A61B 5/0536 (20130101) A61B 5/0537 (20130101) A61B 5/4519 (20130101) A61B 5/6843 (20130101) A61B 2560/0252 (20130101) A61B 2560/0276 (20130101) A61B 2562/046 (20130101) A61B 2562/0209 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974521 | Hancu et al. |
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APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | Ileana Hancu (Clifton Park, New York); Robert David Darrow (Scotia, New York); Eric William Fiveland (Niskayuna, New York); Xiaofeng Liu (Niskayuna, New York) |
ABSTRACT | The system and method of the invention pertains to an MR-guided breast biopsy procedure, specifically as to quickly identifying the biopsy location. More particularly, the system utilizes a diagnostic imaging modality such as magnetic resonance imaging (MRI) to locate one or more lesions in a human breast. Non-rigid registration between uncompressed screening images (where the lesion has been previously identified) and the compressed biopsy images enables easier identification of the biopsy site, hence shortening the biopsy procedure. |
FILED | Tuesday, February 10, 2015 |
APPL NO | 14/618316 |
ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0555 (20130101) A61B 5/742 (20130101) A61B 5/4312 (20130101) A61B 10/0233 (20130101) Original (OR) Class A61B 2576/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974612 | Pinter et al. |
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APPLICANT(S) | INTOUCH TECHNOLOGIES, INC. (Goleta, California) |
ASSIGNEE(S) | INTOUCH TECHNOLOGIES, INC. (Goleta, California) |
INVENTOR(S) | Marco Pinter (Santa Barbara, California); Timothy C. Wright (Santa Barbara, California); H. Neal Reynolds (Severna Park, Maryland); Fuji Lai (Goleta, California); Yulun Wang (Goleta, California) |
ABSTRACT | A telepresence device may autonomously check patients. The telepresence device may determine the frequency of checking based on whether the patient has a risk factor. The telepresence device may include an image sensor, a thermal camera, a depth sensor, one or more systems for interacting with patients, or the like. The telepresence device may be configured to evaluate the patient's condition using the one or more sensors. The telepresence device may measure physiological characteristics using Eulerian video magnification, may detect pallor, fluid level, or fluid color, may detect thermal asymmetry, may determine a psychological state from body position or movement, or the like. The telepresence device may determine whether the patient is experiencing a potentially harmful condition, such as sepsis or stroke, and may trigger an alarm if so. To overcome alarm fatigue, the telepresence device may annoy a care provider until the care provider responds to an alarm. |
FILED | Thursday, February 13, 2014 |
APPL NO | 14/091292 |
ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0008 (20130101) A61B 5/0013 (20130101) A61B 5/015 (20130101) A61B 5/0022 (20130101) A61B 5/024 (20130101) A61B 5/0075 (20130101) A61B 5/0077 (20130101) A61B 5/165 (20130101) A61B 5/741 (20130101) A61B 5/742 (20130101) A61B 5/746 (20130101) A61B 5/1128 (20130101) A61B 5/02055 (20130101) A61B 5/4064 (20130101) A61B 5/4809 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) A61B 19/2203 (20130101) Original (OR) Class A61B 34/30 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1689 (20130101) B25J 11/009 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) G05D 2201/0206 (20130101) Electric Digital Data Processing G06F 19/3418 (20130101) Pictorial Communication, e.g Television H04N 7/148 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974745 | Mannino et al. |
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FUNDED BY |
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APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
INVENTOR(S) | Raphael J. Mannino (Glen Gardner, New Jersey); Susan Gould-Fogerite (Annandale, New Jersey); Sara L. Krause-Elsmore (Kearny, New Jersey); David Delmarre (Jersey City, New Jersey); Ruying Lu (New Providence, New Jersey) |
ABSTRACT | Disclosed are novel methods for making cochleates and cochleate compositions that include introducing a cargo moiety to a liposome in the presence of a solvent. Also disclosed are cochleates and cochleate compositions that include an aggregation inhibitor, and optionally, a cargo moiety. Additionally, anhydrous cochleates that include a protonized cargo moiety, a divalent metal cation and a negatively charge lipid are disclosed. Methods of using the cochleate compositions of the invention, including methods of administration, are also disclosed. |
FILED | Thursday, January 30, 2014 |
APPL NO | 14/168752 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1274 (20130101) A61K 9/1277 (20130101) Original (OR) Class A61K 31/00 (20130101) A61K 31/60 (20130101) A61K 31/135 (20130101) A61K 31/167 (20130101) A61K 31/395 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 38/12 (20130101) A61K 38/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974758 | Spiegel et al. |
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FUNDED BY |
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APPLICANT(S) | Enzo Therapeutics, Inc. (Farmingdale, New York); Virginia Commonwealth University (Richmond, Virginia) |
ASSIGNEE(S) | Enzo Therapeutics, Inc. (Farmingdale, New York); Virginia Commonwealth University (Richmond, Virginia) |
INVENTOR(S) | Sarah Spiegel (Richmond, Virginia); Robert Elliot Zipkin (Wynnewood, Pennsylvania); Jeffrey Kroll Adams (Fort Washington, Pennsylvania) |
ABSTRACT | Provided are inhibitors of sphingosine kinase Type I that are useful in a number of applications, indications and diseases, as well as for monitoring pharmacokinetics and patient management. These compounds are applicable to treating tumors of the central nervous system, such as glioblastoma multiforme (GBM). |
FILED | Tuesday, June 14, 2016 |
APPL NO | 15/181826 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/135 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 215/28 (20130101) C07C 217/64 (20130101) C07C 233/18 (20130101) C07C 323/32 (20130101) Heterocyclic Compounds C07D 263/06 (20130101) C07D 295/092 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974759 | Chen |
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FUNDED BY |
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APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
INVENTOR(S) | Peng-Sheng Chen (Indianapolis, Indiana) |
ABSTRACT | Methods of treating orthostatic hypotension are disclosed. The methods include administering to a subject in need thereof an effective amount of a beta 2 (β2) adrenoceptor antagonist, and in particular, the specific β2 adrenoceptor antagonist, 3-(isopropylamino)-1-[(7-methyl-4-indanyl)oxy]butan-2-ol. |
FILED | Thursday, May 29, 2014 |
APPL NO | 14/290362 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) Original (OR) Class A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974767 | Froehner et al. |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Stanley C. Froehner (Seattle, Washington); Nicholas P. Whitehead (Seattle, Washington) |
ABSTRACT | The invention provides methods and compositions for treating neuromuscular diseases including, but not limited to muscular dystrophies. It is demonstrated herein that statin drugs are therapeutic for neuromuscular disease, including, but not limited to muscular dystrophies. |
FILED | Tuesday, July 14, 2015 |
APPL NO | 14/798877 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/40 (20130101) A61K 31/366 (20130101) Original (OR) Class A61K 31/405 (20130101) A61K 31/519 (20130101) A61K 31/4418 (20130101) A61K 31/4985 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974782 | Feng et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Yan Feng (Shanghai, China PRC); Ottavio Arancio (New York, New York); Shixian Deng (White Plains, New York); Donald W. Landry (New York, New York) |
ABSTRACT | The invention provides for compounds that are phosphodiesterase inhibitors. The invention further provides for a method for screening compounds that bind to and modulate a phosphosdiesterase protein. The invention also provides methods for treating conditions associated with accumulated amyloid-beta peptide deposit accumulations by administering a phosphodiesterase-binding compound to a subject. |
FILED | Friday, August 12, 2016 |
APPL NO | 15/235736 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4706 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974788 | Rosenzweig et al. |
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FUNDED BY |
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APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Anthony Rosenzweig (Newton, Massachusetts); Saumya Das (Lexington, Massachusetts); Alan C. Rigby (Newton, Massachusetts) |
ABSTRACT | The present invention relates to the treatment of acquired and genetic heart conditions in a subject by the inhibition of SGK1, including Long QT syndrome and cardiovascular disease, including dilated cardiomyopathy. Cardiovascular diseases treatable by SGK1 inhibition include heart failure, arrhythmia, ischemic injury, ischemic infarction, cardiac fibrosis, vascular proliferation, restenosis, dilated cardiomyopathy, and stent failure. The present invention also identifies selective inhibitors of SGK1. The method comprises administering to the subject a therapeutically effective amount of an inhibitor of SG. |
FILED | Friday, September 26, 2014 |
APPL NO | 15/024943 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) Original (OR) Class A61K 38/43 (20130101) Peptides C07K 16/40 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974789 | Marugan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of Health and Human (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
INVENTOR(S) | Juan Jose Marugan (Gaithersburg, Maryland); Noel Southall (Potomac, Maryland); Ehud Goldin (Rockville, Maryland); Wei Zheng (Potomac, Maryland); Samarjit Patnaik (Gaithersburg, Maryland); Ellen Sidransky (Bethesda, Maryland); Omid Motabar (Darnestown, Maryland); Wendy Westbroek (Rockville, Maryland) |
ABSTRACT | Substituted pyrazolopyrimidines and dihydropyrazolopyrimidines and related compounds, their methods of manufacture, compositions containing these compounds, and methods of use of these compounds in treating lysosomal storage disorders such as Gaucher disease are described herein. The compounds are of general Formula (I) in which variables R1-R7 and X are described in the application. |
FILED | Thursday, April 28, 2016 |
APPL NO | 15/141275 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/5377 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974796 | Desai et al. |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Sanjay A. Desai (Potomac, Maryland); Ajay D. Pillai (Hyderabad, India) |
ABSTRACT | Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein. |
FILED | Monday, July 18, 2016 |
APPL NO | 15/213181 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/50 (20130101) A61K 31/50 (20130101) A61K 31/165 (20130101) A61K 31/165 (20130101) A61K 31/421 (20130101) A61K 31/423 (20130101) A61K 31/423 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/553 (20130101) Original (OR) Class A61K 31/554 (20130101) A61K 31/554 (20130101) A61K 31/4155 (20130101) A61K 31/4155 (20130101) A61K 31/4245 (20130101) A61K 31/4245 (20130101) A61K 31/4355 (20130101) A61K 31/4355 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/4741 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 263/57 (20130101) C07D 281/16 (20130101) C07D 403/08 (20130101) C07D 413/14 (20130101) C07D 417/06 (20130101) C07D 491/048 (20130101) C07D 498/04 (20130101) C07D 513/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974801 | McGavern et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Dorian B. McGavern (Gaithersburg, Maryland); Theodore Roth (Birmingham, Alabama) |
ABSTRACT | Disclosed is a method of treating or preventing a disease or disorder of the central nervous system (CNS) in a patient comprising administering transcranially, for example, directly to the skull, an effective amount of an anti-inflammatory agent to the patient. Examples of the anti-inflammatory agent include glutathione and inhibitors of purinergic receptors such as P2X4, P2X7, P2Y6, and P2Y12 receptors. Examples of disease or disorder of the CNS include brain injury, particularly traumatic brain injury, inflammation, infection, degeneration of brain cells, stroke, brain edema, tumor, Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Also disclosed is a kit comprising at least one anti-inflammatory agent and printed materials containing instructions for transcranially administering the anti-inflammatory agent to the patient having a disease or disorder of the CNS. |
FILED | Monday, April 11, 2016 |
APPL NO | 15/095957 |
ART UNIT | 1675 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 9/7023 (20130101) A61K 31/05 (20130101) A61K 31/22 (20130101) A61K 31/26 (20130101) A61K 31/64 (20130101) A61K 31/235 (20130101) A61K 31/355 (20130101) A61K 31/375 (20130101) A61K 31/385 (20130101) A61K 31/522 (20130101) A61K 31/7076 (20130101) Original (OR) Class A61K 38/05 (20130101) A61K 38/063 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974809 | Furcht et al. |
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FUNDED BY |
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APPLICANT(S) | Leo T. Furcht (Golden Valley, Minnesota); Catherine M. Verfaillie (Leuven, Belgium); Morayma Reyes (Sammamish, Washington) |
ASSIGNEE(S) | ABT Holding Company (Cleveland, Ohio) |
INVENTOR(S) | Leo T. Furcht (Golden Valley, Minnesota); Catherine M. Verfaillie (Leuven, Belgium); Morayma Reyes (Sammamish, Washington) |
ABSTRACT | The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic uses for the isolated cells. |
FILED | Wednesday, April 01, 2009 |
APPL NO | 12/416627 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 48/00 (20130101) A61K 2035/124 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0607 (20130101) C12N 2501/11 (20130101) C12N 2501/105 (20130101) C12N 2501/135 (20130101) C12N 2501/235 (20130101) C12N 2503/00 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 207/07049 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974810 | Furcht et al. |
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FUNDED BY |
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APPLICANT(S) | Leo T. Furcht (Golden Valley, Minnesota); Catherine M. Verfaillie (Leuven, Belgium); Morayma Reyes (Sammamish, Washington) |
ASSIGNEE(S) | ABT Holding Company (Cleveland, Ohio) |
INVENTOR(S) | Leo T. Furcht (Golden Valley, Minnesota); Catherine M. Verfaillie (Leuven, Belgium); Morayma Reyes (Sammamish, Washington) |
ABSTRACT | The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic uses for the isolated cells. |
FILED | Wednesday, April 01, 2009 |
APPL NO | 12/416672 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 48/00 (20130101) A61K 2035/124 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0607 (20130101) C12N 2501/11 (20130101) C12N 2501/105 (20130101) C12N 2501/135 (20130101) C12N 2501/235 (20130101) C12N 2503/00 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 207/07049 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974811 | Furcht et al. |
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FUNDED BY |
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APPLICANT(S) | Leo T. Furcht (Golden Valley, Minnesota); Catherine M. Verfaillie (Leuven, Belgium); Morayma Reyes (Sammamish, Washington) |
ASSIGNEE(S) | ABT Holding Company (Cleveland, Ohio) |
INVENTOR(S) | Leo T. Furcht (Golden Valley, Minnesota); Catherine M. Verfaillie (Leuven, Belgium); Morayma Reyes (Sammamish, Washington) |
ABSTRACT | The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic uses for the isolated cells. |
FILED | Wednesday, April 01, 2009 |
APPL NO | 12/416700 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 48/00 (20130101) A61K 2035/124 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0607 (20130101) C12N 2501/11 (20130101) C12N 2501/105 (20130101) C12N 2501/135 (20130101) C12N 2501/235 (20130101) C12N 2503/00 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 207/07049 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974828 | Ting et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Kang Ting (Beverly Hills, California); Chia Soo (Beverly Hills, California) |
ABSTRACT | This application is drawn to a method of using an isoform NELL-1 peptide, and compositions thereof for bone formation or for treating, preventing, or ameliorating osteoporosis. |
FILED | Wednesday, September 14, 2016 |
APPL NO | 15/265680 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/32 (20130101) A61K 35/32 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0092 (20130101) A61M 2037/0007 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/303 (20130101) Peptides C07K 14/47 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974830 | Debinski et al. |
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FUNDED BY |
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APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
INVENTOR(S) | Waldemar Debinski (Winston-Salem, North Carolina); Jill Wykosky (LaJolla, California); Denise Mazess Herpai (Winston-Salem, North Carolina) |
ABSTRACT | The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme. |
FILED | Tuesday, February 09, 2016 |
APPL NO | 15/018991 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/45 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 38/2086 (20130101) A61K 45/06 (20130101) A61K 47/64 (20170801) A61K 47/642 (20170801) A61K 47/6801 (20170801) A61K 49/0002 (20130101) Peptides C07K 14/52 (20130101) C07K 14/705 (20130101) Enzymes C12Y 204/02036 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974848 | Sampson et al. |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | John H. Sampson (Durham, North Carolina); Duane A. Mitchell (Durham, North Carolina); Kristen A. Batich (Durham, North Carolina); Michael D. Gunn (Durham, North Carolina) |
ABSTRACT | Pre-conditioning a vaccine site with a potent recall antigen such as tetanus/diphtheria (Td) toxoid can significantly improve the lymph node homing and efficacy of tumor antigen-specific DC vaccines. Patients given Td had enhanced DC migration bilaterally and significantly improved survival. In mice, Td pre-conditioning also enhanced bilateral DC migration and suppressed tumor growth in a manner dependent on the chemokines CCL3 and CCL21 and Td-activated CD4+ T cells. Interference with any component of this axis markedly reduced Td-mediated DC migration and antitumor responses. Our clinical studies and corroborating investigations in mice suggest that pre-conditioning with a potent recall antigen represents a viable strategy to increase DC homing to lymph nodes and improve antitumor immunotherapy. |
FILED | Friday, November 14, 2014 |
APPL NO | 15/036878 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/195 (20130101) A61K 39/05 (20130101) A61K 39/08 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/092 (20130101) A61K 39/102 (20130101) A61K 49/06 (20130101) A61K 49/0008 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/58 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/585 (20130101) A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) A61K 2039/55544 (20130101) Peptides C07K 14/33 (20130101) C07K 14/34 (20130101) C07K 14/285 (20130101) C07K 14/523 (20130101) C07K 14/3156 (20130101) C07K 14/4748 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16134 (20130101) C12N 2710/16171 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974849 | Nakagawa et al. |
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APPLICANT(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
ASSIGNEE(S) | Bioventures, LLC (Little Rock, Arkansas) |
INVENTOR(S) | Mayumi Nakagawa (Little Rock, California); Byeong S. Chang (Thousand Oaks, California) |
ABSTRACT | Peptides and compositions for a therapeutic vaccine to treat persons infected with human papilloma virus are presented. Methods of using the compositions and treating persons infected with human papilloma virus, including those at risk of cancer or already with cancer from human papilloma virus, are presented. |
FILED | Saturday, October 11, 2014 |
APPL NO | 15/028760 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/0021 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 47/26 (20130101) A61K 47/183 (20130101) A61K 2039/585 (20130101) A61K 2039/55588 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20022 (20130101) C12N 2710/20034 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974850 | Croyle et al. |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Maria A. Croyle (Austin, Texas); Stephen Clay Schafer (Austin, Texas) |
ABSTRACT | Immunogenic compositions comprising viral vectors and surfactants are provided. Methods for administration and preparation of such compositions are also provided. |
FILED | Friday, March 25, 2016 |
APPL NO | 15/081601 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/543 (20130101) A61K 2039/55555 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/88 (20130101) C12N 2710/10343 (20130101) C12N 2710/10351 (20130101) C12N 2710/10371 (20130101) C12N 2760/14134 (20130101) C12N 2760/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974851 | Jiang et al. |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Baoming Jiang (Duluth, Georgia); Roger I. Glass (Atlanta, Georgia); Yuhuan Wang (Lilburn, Georgia); Jon Gentsch (Atlanta, Georgia) |
ABSTRACT | Immunogenic pharmaceutical compositions including a live, attenuated human rotavirus or an inactivated human rotavirus are provided which are useful for inducing an immunological response against the rotavirus in a subject. Methods of inducing an immunological response to a rotavirus in a subject are provided by administering an immunogenic pharmaceutical composition including a live, attenuated human rotavirus or an inactivated human rotavirus described herein. |
FILED | Friday, July 01, 2016 |
APPL NO | 15/200837 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/15 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) A61K 2039/55505 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2720/12334 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974853 | McCoy et al. |
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APPLICANT(S) | 13 Therapeutics, Inc. (Portland, Oregon) |
ASSIGNEE(S) | 13THERAPEUTICS, INC. (Portland, Oregon) |
INVENTOR(S) | Sharon L. McCoy (Portland, Oregon); Steven H. Hefeneider (Portland, Oregon) |
ABSTRACT | Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-α secretion through interaction with toll-like receptors. Experiments are described illustrating the efficacy of the compounds in treating otitis media. |
FILED | Tuesday, October 06, 2015 |
APPL NO | 14/876298 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/285 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/005 (20130101) C07K 14/07 (20130101) C07K 14/47 (20130101) C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974854 | Diamond |
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APPLICANT(S) | CITY OF HOPE (Duarte, California) |
ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | Don J. Diamond (Glendora, California) |
ABSTRACT | Highly effective vaccine compositions are constructed according to the methods of this invention. The methods are amenable to use with any peptidic antigen sequence and involve covalent attachment of an immunostimulatory nucleotide sequence to an antigenic peptide sequence. Preferred antigenic peptides are fusion peptides made up of one or more CTL epitope peptides in sequence fused to a T helper peptide. |
FILED | Thursday, June 11, 2015 |
APPL NO | 14/736897 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/605 (20130101) A61K 2039/6025 (20130101) A61K 2039/55516 (20130101) A61K 2039/55561 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16022 (20130101) C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974866 | Kabanov et al. |
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APPLICANT(S) | Alexander V. Kabanov (Omaha, Nebraska); Jing Tong (Omaha, Nebraska) |
ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
INVENTOR(S) | Alexander V. Kabanov (Omaha, Nebraska); Jing Tong (Omaha, Nebraska) |
ABSTRACT | The present invention provides polymer-polypeptide conjugates comprising a poly(2-oxazoline) amphiphilic block copolymer linked to a polypeptide and methods of use thereof. |
FILED | Thursday, April 07, 2011 |
APPL NO | 13/634717 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/59 (20170801) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974868 | Gao et al. |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Xiamen University (Xiamen, Fujian, China PRC) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Xiamen University (Xiamen, China PRC) |
INVENTOR(S) | Jinhao Gao (Fujian, China PRC); Xiaoyuan Chen (Potomac, Maryland); Zenghuan Zhao (Chongqing, China PRC) |
ABSTRACT | Disclosed are nanoparticles comprising octapod iron oxide having eight trigonal bipyramidal arms and a method of preparing the same. The nanoparticles are prepared by heating a mixture of a ferric carboxylate, a carboxylic acid, a chloride salt, water, and a non-polar solvent, to a temperature above about 300° C. Also disclosed is a method of magnetic resonance imaging a tissue in a mammal, comprising use of the aforesaid nanoparticles. |
FILED | Monday, June 03, 2013 |
APPL NO | 14/895745 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/06 (20130101) A61K 49/08 (20130101) A61K 49/1818 (20130101) A61K 49/1833 (20130101) Original (OR) Class A61K 49/1851 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974869 | Berkman et al. |
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APPLICANT(S) | Cancer Targeted Technology LLC (Woodinville, Washington) |
ASSIGNEE(S) | Cancer Targeted Technology LLC (Woodinville, Washington) |
INVENTOR(S) | Clifford Berkman (Pullman, Washington); Bea Langton-Webster (Woodinville, Washington); Xiaobing Wang (Redmond, Washington) |
ABSTRACT | Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells. |
FILED | Wednesday, August 24, 2016 |
APPL NO | 15/246483 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/04 (20130101) A61K 51/0489 (20130101) Original (OR) Class A61K 51/0497 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/004 (20130101) C07B 2200/05 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/2458 (20130101) C07F 9/6515 (20130101) C07F 9/6524 (20130101) C07F 9/6527 (20130101) C07F 9/6561 (20130101) C07F 9/65583 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974870 | Achilefu et al. |
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APPLICANT(S) | Washington University (St. Louis, Missouri) |
ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
INVENTOR(S) | Samuel Achilefu (St. Louis, Missouri); Kvar Black (St. Louis, Missouri) |
ABSTRACT | The present invention encompasses compositions comprising two spectrally distinct radionuclides separated by a site susceptible to cleavage. Compositions of the invention may be used to detect enzyme activity and/or image diseases associated with said enzyme activity. |
FILED | Tuesday, June 09, 2015 |
APPL NO | 14/734761 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/088 (20130101) Original (OR) Class A61K 51/1251 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974883 | Khandaker et al. |
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APPLICANT(S) | UNIVERSITY OF CENTRAL OKLAHOMA (Edmond, Oklahoma) |
ASSIGNEE(S) | University of Central Oklahoma (Edmond, Oklahoma) |
INVENTOR(S) | Morshed Khandaker (Edmond, Oklahoma); Shahram Riahinezhad (Edmond, Oklahoma) |
ABSTRACT | The present invention provides processes for combined applications of making grooves on an implant surface, applying MgO nanoparticles with PMMA cement, restricting the cement movement by PCL nanofiber and tethering biomolecules with PCL nanofiber to enhance mechanical stability and osseointegration of PMMA cement with bone. This is achieved through enhanced osteoconductive properties, roughness, and less viable fracture originating sites at the bone-cement interface. Such combined applications of nanoparticle and nanofiber on the mechanical stability and osseointegration of cemented implant is heretofore unknown, but as provided by the present invention can solve the debonding problem of cemented implant from bone. |
FILED | Thursday, August 10, 2017 |
APPL NO | 15/674309 |
ART UNIT | 3738 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/866 (20130101) A61B 2017/564 (20130101) A61B 2017/8655 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2846 (20130101) A61F 2/3601 (20130101) A61F 2/30723 (20130101) A61F 2/30734 (20130101) A61F 2002/30736 (20130101) A61F 2310/00011 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1841 (20130101) A61K 38/1875 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/02 (20130101) A61L 24/06 (20130101) A61L 24/0015 (20130101) A61L 24/102 (20130101) Original (OR) Class A61L 24/108 (20130101) A61L 2300/404 (20130101) A61L 2300/414 (20130101) A61L 2430/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974953 | Greenberg et al. |
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APPLICANT(S) | Robert Jay Greenberg (Los Angeles, California); Kelly Hobart McClure (Simi Valley, California); James Singleton Little (Saugus, California); Rongqing Dai (Valencia, California); Arup Roy (Santa Clarita, California); Richard Agustin Castro (Pasadena, California); John Reinhold (Tarzana, California); Kea-Tiong Tang (Temple City, California); Sumit Yadav (Los Angeles, California); Chunhong Zhou (Pasadena, California); Dao Min Zhou (Saugus, California); Pishoy Maksy (Sherman Oaks, California) |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Robert Jay Greenberg (Los Angeles, California); Kelly Hobart McClure (Simi Valley, California); James Singleton Little (Saugus, California); Rongqing Dai (Valencia, California); Arup Roy (Santa Clarita, California); Richard Agustin Castro (Pasadena, California); John Reinhold (Tarzana, California); Kea-Tiong Tang (Temple City, California); Sumit Yadav (Los Angeles, California); Chunhong Zhou (Pasadena, California); Dao Min Zhou (Saugus, California); Pishoy Maksy (Sherman Oaks, California) |
ABSTRACT | An apparatus for controlling the stimulation of neural tissue which includes a neural stimulator, an input device for providing input to the neural stimulator for neural stimulation, at least one electrode electrically connected to and driven by the neural stimulator and suitable to stimulate neural tissue, a device capable of determining a charge per phase by calculating a discrete integral of the wave form of the input for the at least one electrode, a calculating device for comparing the charge per phase to a predetermined maximum and determining a reduced stimulation for the at least one electrode by the amount necessary not to exceed the predetermined maximum for the at least one electrode, and a current pulse generator for stimulating the neural tissue according to the reduced stimulation level. |
FILED | Monday, March 26, 2012 |
APPL NO | 13/430356 |
ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/0543 (20130101) A61N 1/0551 (20130101) A61N 1/36046 (20130101) Original (OR) Class A61N 1/36142 (20130101) A61N 1/36185 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975066 | Boyd et al. |
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FUNDED BY |
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APPLICANT(S) | Artificial Cell Technologies, Inc. (New Haven, Connecticut) |
ASSIGNEE(S) | ARTIFICIAL CELL TECHNOLOGIES, INC. (New Haven, Connecticut) |
INVENTOR(S) | James Gorham Boyd (Madison, Connecticut); Naveen Palath (Cheshire, Connecticut); Edwin Jonathan Cardenas (Waterford, Connecticut) |
ABSTRACT | Layer by layer (“LBL”) construction of products by tangential flow filtration (TFF), or the like, is described, including computer controlled automation of such procedure for production of a multilayer coated core. |
FILED | Friday, May 22, 2015 |
APPL NO | 14/719363 |
ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 39/00 (20130101) Separation B01D 21/262 (20130101) Original (OR) Class B01D 61/20 (20130101) B01D 61/22 (20130101) B01D 2221/10 (20130101) Apparatus for Applying Fluent Materials to Surfaces, in General B05C 11/10 (20130101) B05C 19/06 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975848 | Smith, III et al. |
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APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Bryn Mawr College (Bryn Mawr, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Bryn Mawr College (Bryn Mawr, Pennsylvania) |
INVENTOR(S) | Amos B. Smith, III (Merion, Pennsylvania); Joseph Sodroski (Medford, Massachusetts); Navid Madani (Newton, Massachusetts); Bruno Melillo (Philadelphia, Pennsylvania); Judith M. LaLonde (Havertown, Pennsylvania); Amy M. Princiotto (Attleboro, Massachusetts) |
ABSTRACT | The disclosure provides compositions and methods for sensitizing primary HIV-1, including transmitted/founder viruses, to neutralization by monoclonal antibodies, e.g., those directed against CD4-induced (CD4i) epitopes and the V3 region. In certain embodiments, the disclosure relates to the use of small molecules as microbicides to inhibit HIV-1 infection directly and to sensitize primary HIV-1 to neutralization by readily elicited antibodies. |
FILED | Thursday, August 13, 2015 |
APPL NO | 15/503207 |
ART UNIT | 1671 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 39/42 (20130101) Acyclic or Carbocyclic Compounds C07C 279/12 (20130101) Original (OR) Class C07C 2602/08 (20170501) Peptides C07K 14/005 (20130101) C07K 16/1063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975863 | Roberts et al. |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Edward Roberts (Fallbrook, California); Hugh Rosen (La Jolla, California); Steven Brown (San Diego, California); Miguel A. Guerrero (San Diego, California); Xuemei Peng (La Jolla, California); Ramulu Poddutoori (La Jolla, California) |
ABSTRACT | Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphingosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided. |
FILED | Friday, September 22, 2017 |
APPL NO | 15/713237 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4245 (20130101) Heterocyclic Compounds C07D 263/32 (20130101) C07D 271/06 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 413/04 (20130101) C07D 413/14 (20130101) C07D 471/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975868 | Ye |
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FUNDED BY |
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APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Keqiang Ye (Lilburn, Georgia) |
ABSTRACT | In certain embodiments, the disclosure relates to 7,8-dihydoxyflavone and 7,8-substituted flavone derivatives, such as those described by formula provided herein, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing diseases or conditions related to BDNF and TrkB activity, such as psychiatric disorders, depression, post-traumatic stress disorder, and autism spectrum disorders, stroke, Rett syndrome, Parkinson's disease, and Alzheimer's disease by administering effective amounts of pharmaceutical compositions comprising compounds disclosed herein to a subject in need thereof. In certain embodiments, it is contemplated that the 7,8-substituted flavone derivatives disclosed herein are prodrugs of 7,8-dihydoxyflavone and analogs. |
FILED | Friday, May 12, 2017 |
APPL NO | 15/593654 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 311/28 (20130101) C07D 311/30 (20130101) Original (OR) Class C07D 311/36 (20130101) C07D 311/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975879 | Abou-Gharbia et al. |
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FUNDED BY |
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APPLICANT(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
INVENTOR(S) | Magid Abou-Gharbia (Exton, Pennsylvania); Wayne E. Childers (New Hope, Pennsylvania); Rogelio L. Martinez (Trenton, New Jersey); Mercy M. Ramanjulu (King of Prussia, Pennsylvania); Benjamin E. Blass (Eagleville, Pennsylvania) |
ABSTRACT | Pharmaceutical compositions of the invention comprise compounds, compositions, methods useful for the treatment of drug addiction, drug withdrawal, and diseases or conditions that involve dysregulation of glutamate homeostasis in it etiology. |
FILED | Wednesday, June 04, 2014 |
APPL NO | 14/895681 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 205/08 (20130101) C07D 403/06 (20130101) Original (OR) Class C07D 471/08 (20130101) C07D 487/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975885 | St. John et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
INVENTOR(S) | Sarah Emma St. John (West Lafayette, Indiana); Andrew D. Mesecar (West Lafayette, Indiana) |
ABSTRACT | This invention pertains to materials and methods for the treatment of patients with coronavirus infection and the control of zoonotic disease outbreaks using broad-spectrum non-covalent coronavirus protease inhibitors. |
FILED | Friday, April 28, 2017 |
APPL NO | 15/581122 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 209/20 (20130101) C07D 211/62 (20130101) C07D 233/64 (20130101) C07D 235/08 (20130101) C07D 249/18 (20130101) C07D 307/81 (20130101) C07D 401/12 (20130101) C07D 409/12 (20130101) C07D 409/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975896 | Marineau et al. |
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APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Jason J. Marineau (Franklin, Massachusetts); James E. Bradner (Weston, Massachusetts); Wei Zhang (Sharon, Massachusetts); Jun Qi (Sharon, Massachusetts); Michael R. McKeown (Brookline, Massachusetts); Harry Hongning Fu (Newton, Massachusetts); Shuai Liu (Dorchester, Massachusetts) |
ABSTRACT | The present invention provides novel compounds of any one of Formulae (I) to (IV), and pharmaceutically compositions thereof. Compounds of any one of Formulae (I) to (IV) are believed to be inhibitors of bromodomain-containing proteins (e.g., bromo and extra terminal proteins (BETs)). Also provided are methods, uses, and kits using the inventive compounds and pharmaceutical compositions for inhibiting the activity of the bromodomain-containing proteins and for treating and/or preventing in a subject in need thereof diseases associated with bromodomain-containing proteins, such as proliferative diseases. |
FILED | Friday, July 25, 2014 |
APPL NO | 14/907339 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Heterocyclic Compounds C07D 413/10 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class C07D 491/048 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975916 | Yin et al. |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Peng Yin (Brookline, Massachusetts); Diming Wei (Cambridge, Massachusetts); Mingjie Dai (Boston, Massachusetts); Cameron Myhrvold (Cambridge, Massachusetts); Yonggang Ke (Atlanta, Georgia); Ralf Jungmann (Cambridge, Massachusetts) |
ABSTRACT | The invention provides SST motifs of controlled size and shape, comprised of a plurality of oligonucleotides, and methods for their synthesis. The motifs are formed, at least in part, by the self-assembly of single stranded oligonucleotides into curved, corrugated or twisted structures. The location of each oligonucleotide in the resultant motif is known. Accordingly, the motifs may be modified with specificity. |
FILED | Wednesday, November 06, 2013 |
APPL NO | 14/440907 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 21/04 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1031 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975918 | Xu et al. |
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APPLICANT(S) | Van Andel Research Institute (Grand Rapids, Michigan); Shanghai Institute of Materia Medica, Chinese Academy of Sciences (Shanghai, China PRC) |
ASSIGNEE(S) | VAN ANDEL RESEARCH INSTITUTE (Grand Rapids, Michigan); SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (Shanghai, China PRC) |
INVENTOR(S) | Huaqiang Eric Xu (Grand Rapids, Michigan); Yuanzheng He (Grand Rapids, Michigan); Karsten Melcher (Grand Rapids, Michigan); Wei Yi (Shanghai, China PRC); Jingjing Shi (Shanghai, China PRC) |
ABSTRACT | The present invention relates to novel glucocorticoid compounds. The invention also relates to methods of using these compounds, the synthesis of these compounds, and to compositions and formulations comprising the glucocorticoid compounds, and uses thereof. |
FILED | Thursday, September 25, 2014 |
APPL NO | 15/024496 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Steroids C07J 3/005 (20130101) C07J 5/0053 (20130101) C07J 71/0047 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975922 | Agris et al. |
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APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
ASSIGNEE(S) | The Research Foundation For The State University of New York (Albany, New York); North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Paul F. Agris (Albany, New York); Carol Hall (Raleigh, North Carolina); Xingqing Xiao (Raleigh, North Carolina) |
ABSTRACT | Disclosed are peptides that exhibit good binding to the anticodon stem and loop of human lysine tRNA species, tRNALys3. The starting point was the 15-amino-acid sequence, RVTHHAFLGAHRTVG, found to bind selectively to hypermodified tRNALys3. The peptide backbone conformation was determined via atomistic simulation of the peptide-ASLLys3complex and then held fixed throughout the search. Analysis of the binding structure and the various contributions to the binding energy shows that: 1) two hydrophilic residues (asparagine (ASN) at site 11 and the cysteine (CYS) at site 12) “recognize” the ASLLys3 due to the VDW energy, and thereby contribute to its binding specificity, and 2) the positively-charged arginines (ARG) at sites 4 and 13 preferentially attract the negatively-charged sugar rings and the phosphate linkages, and thereby contribute to the binding affinity. |
FILED | Tuesday, October 21, 2014 |
APPL NO | 15/030739 |
ART UNIT | 1675 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975923 | Baric et al. |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Ralph Steven Baric (Haw River, North Carolina); Lisa Chon Lindesmith (Apex, North Carolina); Kari Moore Debbink (Durham, North Carolina); Eric Francis Donaldson (Durham, North Carolina); Jesica Anne Swanstrom (Morrisville, North Carolina) |
ABSTRACT | The present invention provides methods and compositions comprising a chimeric norovirus capsid protein comprising a norovirus VP1 major capsid protein backbone comprising a norovirus epitope selected from the group consisting of: a) Epitope A; b) Epitope B; c) Epitope C; d) Epitope D; e) Epitope E; f) Epitope F; and g) any combination of (a) through (f) above, wherein the norovirus epitope is from a norovirus strain that is different from the norovirus VP1 major capsid protein backbone. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/213469 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/16022 (20130101) C12N 2770/16034 (20130101) C12N 2770/36143 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975924 | Rao et al. |
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APPLICANT(S) | THE CATHOLIC UNIVERSITY OF AMERICA (Washington, District of Columbia) |
ASSIGNEE(S) | The Catholic University of America (Washington, District of Columbia) |
INVENTOR(S) | Venigalla B. Rao (Silver Spring, Maryland); Wadad Alsalmi (Washington, District of Columbia) |
ABSTRACT | An approach of producing recombinant trimers that mimic native HIV-1 envelope trimers is developed. A recombinant protein forming the recombinant trimers encompasses a recombinant HIV-1 gp140 fused to a tag through a linker at C-terminus of the recombinant HIV-1 gp140. The linker is sufficiently long so that the tag is accessible for binding by a binding molecule bound on a solid matrix. After expressed in a cell, the recombinant protein is secreted into the culture medium and assembles into recombinant trimers therein. The recombinant trimers may be directly purified from the culture medium. Cleaved and uncleaved trimers from different clade viruses are produced. |
FILED | Thursday, July 23, 2015 |
APPL NO | 14/806742 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/7023 (20130101) A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/54 (20130101) A61K 2039/627 (20130101) Peptides C07K 1/22 (20130101) C07K 1/36 (20130101) C07K 14/005 (20130101) Original (OR) Class C07K 14/162 (20130101) C07K 2319/00 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/40 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16022 (20130101) C12N 2740/16043 (20130101) C12N 2740/16051 (20130101) C12N 2740/16111 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16234 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975925 | Stevens et al. |
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APPLICANT(S) | GLAXOSMITHKLINE BIOLOGICALS S.A. (Rixensart, Belgium); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
ASSIGNEE(S) | GLAXOSMITHKLINE BIOLOGICALS S.A. (Rixensart, Belgium); THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. HEALTH and HUMAN SERVICES (Washington, District of Columbia) |
INVENTOR(S) | James Stevens (Atlanta, Georgia); Ruben Donis (Atlanta, Georgia); David Shore (Atlanta, Georgia); Hongquan Wan (Atlanta, Georgia); Ventzislav Bojidarov Vassilev (Rixensart, Belgium) |
ABSTRACT | Novel influenza antigens, novel immunogenic or vaccine compositions, as well as uses of and methods for producing said antigens and compositions, are described. |
FILED | Tuesday, August 26, 2014 |
APPL NO | 14/914431 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1018 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09975937 — Heterodimers of IL-15 and IL-15R alpha to increase thymic output and to treat lymphopenia
US 09975937 | Pavlakis et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED SSTATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
INVENTOR(S) | George N. Pavlakis (Rockville, Maryland); Barbara K. Felber (Rockville, Maryland); Antonio Valentin (Frederick, Maryland); Cristina Bergamaschi (Frederick, Maryland) |
ABSTRACT | The present invention provides method for promoting the maturation and export of T cells from thymic tissue by contacting the thymic tissue with supraphysiological levels of interleukin (IL)-15. The present invention also provides methods for preventing, alleviating, reducing, and/or inhibiting lymphopenia or peripheral depletion of lymphocytes in a patient in need thereof by administering to the patient IL-15. |
FILED | Monday, October 13, 2014 |
APPL NO | 14/512913 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1793 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) A61K 38/2086 (20130101) A61K 45/06 (20130101) A61K 47/48423 (20130101) A61K 47/48507 (20130101) A61K 48/005 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/54 (20130101) C07K 14/5443 (20130101) Original (OR) Class C07K 14/7155 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/163 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975940 | Weiss |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Michael Weiss (Moreland Hills, Ohio) |
ABSTRACT | A single-chain insulin analogue containing a basic side chain at position A8 (Arginine, Histidine, Lysine, or Ornithine), a basic side chain at position B29 (Arginine, Histidine, Lysine, or Ornithine), and a foreshortened C-domain of length 6-11 residues is provided. Residues C1 and C2 of the C-domain have a net negative charge of −1 or −2; C3 is chosen from a group consisting of Gly, Ala, Pro, or Ser; and the remaining C-domain segment is successively derived from the C-domain of IGF-II (RRSR (SEQ ID NO: 18), SRRSR (SEQ ID NO: 17), VSRRSR (SEQ ID NO: 16), RVSRRSR (SEQ ID NO: 15), or SRVSRRSR (SEQ ID NO: 13)). A method of treating a patient with diabetes mellitus or obesity comprises administering a physiologically effective amount of the insulin analogue or a physiologically acceptable salt thereof to a patient. |
FILED | Tuesday, November 22, 2016 |
APPL NO | 15/358977 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/62 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975942 | Debinski et al. |
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APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
ASSIGNEE(S) | Wake Forest University Health Services (Winston-Salem, North Carolina) |
INVENTOR(S) | Waldemar Debinski (Winston-Salem, North Carolina); Carla Lema Tome (Winston-Salem, North Carolina); Sara Ferluga (Trieste, Italy); Poonam S. Sonawane (Winston-Salem, North Carolina) |
ABSTRACT | Provided herein is a construct comprising, in combination: an EphA3, EphA2 and/or EphB2 binding ligand; and at least one effector molecule. In some embodiments, the at least one effector molecule comprises a therapeutic agent, a nanoparticle, a detectable group, a lipid, or a liposome. In some embodiments, the construct is a fusion protein and/or a covalent conjugate. Further provided is a construct comprising in combination: a ligand that binds to EphA2, EphA3 and/or EphB2; a ligand that binds to IL-13Rα2; and at least one effector molecule. Also provided are methods of use thereof for treating cancer. |
FILED | Tuesday, November 11, 2014 |
APPL NO | 15/035560 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/52 (20130101) C07K 14/705 (20130101) Original (OR) Class C07K 14/5437 (20130101) C07K 2319/01 (20130101) C07K 2319/06 (20130101) C07K 2319/09 (20130101) C07K 2319/30 (20130101) C07K 2319/33 (20130101) C07K 2319/55 (20130101) C07K 2319/74 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975959 | Georgiou et al. |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas); Nicholas Marshall (Austin, Texas); John Blazeck (Austin, Texas); Wei-Cheng Lu (Austin, Texas) |
ABSTRACT | Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids. |
FILED | Friday, August 28, 2015 |
APPL NO | 14/839293 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 39/3955 (20130101) A61K 47/48215 (20130101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 16/2887 (20130101) Original (OR) Class C07K 16/2896 (20130101) C07K 2317/622 (20130101) C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/96 (20130101) Enzymes C12Y 307/01003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976011 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Hao Li (Columbia, Missouri); Qingson Yu (Columbia, Missouri); Liang Chen (Columbia, Missouri); Meng Chen (Columbia, Missouri) |
ASSIGNEE(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
INVENTOR(S) | Hao Li (Columbia, Missouri); Qingson Yu (Columbia, Missouri); Liang Chen (Columbia, Missouri); Meng Chen (Columbia, Missouri) |
ABSTRACT | The present invention provides polymer composites reinforced with high aspect ratio reinforcing fillers selected from calcium phosphate nanofibers, nanoplates, submicron fibers, submicron plates, and combinations thereof. The mechanical and biological properties of the inventive composites are enhanced significantly over current polymer composites and may be employed in various biomedical applications, such as dental restorations. |
FILED | Thursday, July 14, 2011 |
APPL NO | 13/183221 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/08 (20130101) Original (OR) Class C08K 2201/011 (20130101) C08K 2201/016 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976122 | Spencer et al. |
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FUNDED BY |
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APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
INVENTOR(S) | David Spencer (Houston, Texas); Priyadharshini Narayanan (Houston, Texas) |
ABSTRACT | Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible pattern recognition receptor adapter, or adapter fragment, and CD40 activity. Also provided are nucleic acid compositions comprising sequences coding for chimeric proteins that include an inducible CD40 peptide and an inducible pattern recognition receptor adapter or adapter fragment. |
FILED | Thursday, July 21, 2016 |
APPL NO | 15/216008 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/4702 (20130101) C07K 14/4705 (20130101) C07K 14/70578 (20130101) C07K 2319/033 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0639 (20130101) Original (OR) Class C12N 7/00 (20130101) C12N 9/90 (20130101) C12N 15/86 (20130101) C12N 2501/52 (20130101) C12N 2501/70 (20130101) C12N 2501/998 (20130101) C12N 2510/00 (20130101) C12N 2710/10343 (20130101) Enzymes C12Y 502/01008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976137 | Scheinberg et al. |
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FUNDED BY |
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APPLICANT(S) | David A. Scheinberg (New York, New York); Michael R. McDevitt (Bronx, New York); Carlos H. Villa (Philadelphia, Pennsylvania); J. Justin Mulvey (New York, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | David A. Scheinberg (New York, New York); Michael R. McDevitt (Bronx, New York); Carlos H. Villa (Philadelphia, Pennsylvania); J. Justin Mulvey (New York, New York) |
ABSTRACT | Provided herein are methods for delivering a molecule in situ to a cell and for treating a cancer via the in situ delivery. The methods comprise contacting or administering to the cell, as two separate components, a morpholino oligonucleotide comprising a targeting moiety followed by a single wall nanotube construct comprising second morpholino oligonucleotides complementary to the first morpholino oligonucleotides and one or both of a therapeutic or diagnostic payload molecule linked to the single wall nanotube construct. Upon self-assembly of a single wall nanotube complex via hybridization of the first morpholino and second complementary morpholino oligonucleotides at the cell, the payload molecule is delivered. Also provided is the two component self-assembly single wall nanotube system and the single wall nanotube construct comprising the second component. |
FILED | Friday, June 27, 2014 |
APPL NO | 14/318112 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 51/1027 (20130101) A61K 51/1093 (20130101) A61K 51/1203 (20130101) A61K 51/1248 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/351 (20130101) C12N 2310/3233 (20130101) C12N 2320/32 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/842 (20130101) Y10S 977/906 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976138 | Prakash et al. |
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FUNDED BY |
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APPLICANT(S) | Thazha P. Prakash (Carlsbad, California); Eric E. Swayze (Encinitas, California); David Corey (Dallas, Texas); Dongbo Yu (Dallas, Texas) |
ASSIGNEE(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
INVENTOR(S) | Thazha P. Prakash (Carlsbad, California); Eric E. Swayze (Encinitas, California); David Corey (Dallas, Texas); Dongbo Yu (Dallas, Texas) |
ABSTRACT | Described are compounds and methods useful for the treatment and investigation of diseases and disorders associated with expanded repeat-containing RNA molecules. |
FILED | Wednesday, August 29, 2012 |
APPL NO | 14/342176 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/323 (20130101) C12N 2310/341 (20130101) C12N 2310/343 (20130101) C12N 2310/344 (20130101) C12N 2310/351 (20130101) C12N 2310/533 (20130101) C12N 2310/3341 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) C12N 2320/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976140 | Tseng et al. |
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FUNDED BY |
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APPLICANT(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Yu-Hua Tseng (Newton, Massachusetts); Hongbin Zhang (Allston, Massachusetts) |
ABSTRACT | This invention reveals a novel miRNA and a novel miRNA-regulated signaling network which controls brown adipogenesis and thermogenic programs, thereby providing a powerful approach for the treatment of obesity and related metabolic diseases. In this regard, the present invention is also directed towards methods of treatment of obesity and excess weight (overweight) and metabolic disorders caused by or aggravated by a subject being overweight or obese. |
FILED | Friday, June 13, 2014 |
APPL NO | 14/896787 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2320/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976143 | Krainer et al. |
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FUNDED BY |
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APPLICANT(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
ASSIGNEE(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
INVENTOR(S) | Adrian Krainer (Huntington Station, New York); Isabel Aznarez (Queens, New York) |
ABSTRACT | Provided herein are methods and compositions for increasing production of a target protein or functional RNA by a cell. |
FILED | Saturday, October 03, 2015 |
APPL NO | 14/874420 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/805 (20130101) C07K 14/4702 (20130101) C07K 14/4736 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3341 (20130101) C12N 2310/3521 (20130101) C12N 2320/11 (20130101) C12N 2320/33 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 101/01205 (20130101) C12Y 304/24087 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976147 | Kortylewski et al. |
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FUNDED BY |
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APPLICANT(S) | City of Hope (Duarte, California) |
ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | Marcin Tomasz Kortylewski (Monrovia, California); Piotr Marek Swiderski (San Dimas, California) |
ABSTRACT | Described herein, inter alia, are STAT-binding nucleic acids-including compositions and methods of using the same. |
FILED | Friday, May 20, 2016 |
APPL NO | 15/160865 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 47/48092 (20130101) A61K 2039/55561 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/117 (20130101) Original (OR) Class C12N 2310/13 (20130101) C12N 2310/17 (20130101) C12N 2310/315 (20130101) C12N 2310/351 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) C12N 2320/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976166 | Schellenberger et al. |
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FUNDED BY |
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APPLICANT(S) | Amunix Operating Inc. (Mountain View, California) |
ASSIGNEE(S) | AMUNIX OPERATING INC. (Mountain View, California) |
INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Chia-wei Wang (Santa Clara, California); Benjamin Spink (San Carlos, California); Willem P. C. Stemmer (Los Gatos, California); Nathan C. Geething (Santa Clara, California) |
ABSTRACT | The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions. |
FILED | Monday, December 21, 2015 |
APPL NO | 14/977035 |
ART UNIT | 1675 — Plants |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/7155 (20130101) C07K 14/8125 (20130101) C07K 14/70521 (20130101) C07K 16/18 (20130101) C07K 16/32 (20130101) C07K 16/40 (20130101) C07K 16/241 (20130101) C07K 16/244 (20130101) C07K 16/2809 (20130101) C07K 16/2863 (20130101) C07K 16/2878 (20130101) C07K 2317/31 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/31 (20130101) C07K 2319/70 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/625 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976169 | Rosen |
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FUNDED BY |
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APPLICANT(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
INVENTOR(S) | Barry P. Rosen (Coral Gables, Florida) |
ABSTRACT | Disclosed are methods of detecting organic arsenicals using genetically modified cells. |
FILED | Monday, July 15, 2013 |
APPL NO | 14/413256 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Original (OR) Class C12Q 1/18 (20130101) C12Q 1/689 (20130101) C12Q 2600/142 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976176 | Bau et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); New York University (New York, New York) |
INVENTOR(S) | Haim H. Bau (Swarthmore, Pennsylvania); William R. Abrams (Merion, Pennsylvania); Eran Geva (Brooklyn, New York); Michael G. Mauk (Wilmington, Delaware); Changchun Liu (Bala Cynwyd, Pennsylvania); Daniel Malamud (New York, New York); Xianbo Qiu (Philadelphia, Pennsylvania) |
ABSTRACT | Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments, isolate, amplify, and detect nucleic acid in a single chamber. In other embodiments, the devices are adapted to isolate and amplify nucleic acids in a reaction chamber, after which the nucleic acids may be communicated to a pervious medium—such as a lateral flow strip—where the user may label and detect the nucleic acids. |
FILED | Thursday, September 08, 2016 |
APPL NO | 15/259416 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 7/52 (20130101) B01L 2300/0663 (20130101) B01L 2300/0681 (20130101) B01L 2300/1855 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976184 | Vogelstein et al. |
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FUNDED BY |
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APPLICANT(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Jian Wu (Baltimore, Maryland); Luis Diaz (Ellicott City, Maryland); Nickolas Papadopoulos (Towson, Maryland); Hanno Matthaei (Bonn, Germany); Ralph Hruban (Baltimore, Maryland); Anirban Maitra (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Jian Wu (Baltimore, Maryland); Luis Diaz (Ellicott City, Maryland); Nickolas Papadopoulos (Towson, Maryland); Hanno Matthaei (Bonn, Germany); Ralph Hruban (Baltimore, Maryland); Anirban Maitra (Baltimore, Maryland) |
ABSTRACT | To help reveal the pathogenesis of these lesions, we purified the DNA from Intraductal Papillary Mucinous Neoplasm (IPMN) cyst fluids from 19 patients and searched for mutations in 169 genes commonly altered in human cancers. We identified recurrent mutations at codon 201 of GNAS. We found that GNAS mutations were present in 66% of IPMNs and that either KRAS or GNAS mutations could be identified in 96%. In eight cases, we could investigate invasive adenocarcinomas that developed in association with IPMNs containing GNAS mutations. In seven of these eight cases, the GNAS mutations present in the IPMNs were also found in the invasive lesion. GNAS mutations were not found in other types of cystic neoplasms of the pancreas or in invasive adenocarcinomas not associated with IPMNs. These data suggest that GNAS mutations can inform the diagnosis and management of patients with cystic pancreatic lesions. |
FILED | Friday, June 22, 2012 |
APPL NO | 14/128478 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976973 | Watkins et al. |
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FUNDED BY |
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APPLICANT(S) | Nicholas Watkins (Attleboro, Massachusetts); Rashid Bashir (Champaign, Illinois); William Rodriguez (Cambridge, Massachusetts); Xuanhong Cheng (Bethlehem, Pennsylvania); Mehmet Toner (Wellesley, Massachusetts); Grace Chen (Cambridge, Massachusetts); Aaron Oppenheimer (Cambridge, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Board of Trustees of the University of Illinois (Urbana, Illinois); Daktari Diagnostics, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Nicholas Watkins (Attleboro, Massachusetts); Rashid Bashir (Champaign, Illinois); William Rodriguez (Cambridge, Massachusetts); Xuanhong Cheng (Bethlehem, Pennsylvania); Mehmet Toner (Wellesley, Massachusetts); Grace Chen (Cambridge, Massachusetts); Aaron Oppenheimer (Cambridge, Massachusetts) |
ABSTRACT | This disclosure relates to methods and devices to count particles of interest, such as cells. The methods include obtaining a fluid sample that may contain particles of interest; counting all types of particles in a portion of the sample using a first electrical differential counter to generate a first total; removing any particles of interest from the portion of the fluid sample; counting any particles remaining in the portion of the fluid sample using a second electrical differential counter after the particles of interest are removed to generate a second total; and calculating a number of particles of interest originally in the fluid sample by subtracting the second total from the first total, wherein the difference is the number of particles of interest in the sample. These methods and related devices can be used, for example, to produce a robust, inexpensive diagnostic kit for CD4+ T cell counting in whole blood samples. |
FILED | Wednesday, November 09, 2011 |
APPL NO | 13/884580 |
ART UNIT | 1677 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 2200/0652 (20130101) B01L 2300/0877 (20130101) Apparatus for Enzymology or Microbiology; C12M 41/36 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/12 (20130101) G01N 15/1245 (20130101) G01N 27/02 (20130101) Original (OR) Class G01N 33/56972 (20130101) G01N 2015/1006 (20130101) G01N 2015/1486 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977016 | DeLong et al. |
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FUNDED BY |
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APPLICANT(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
INVENTOR(S) | Robert DeLong (Manhattan, Kansas); Miranda Hurst (Rogersville, Missouri) |
ABSTRACT | Methods of characterizing nanoparticles, nanoparticle complexes, and their biomolecular interactions are provided. Concurrent excitation and emission wavelength scans are performed and the optimal fluorescence intensity for the intersect of these wavelengths is determined. The intersect is dependent upon the physical characteristics of the particle and can be used to verify, for example, attachment of biomolecules, amount of biomolecules present, and structure of the attached biomolecule. |
FILED | Friday, November 04, 2016 |
APPL NO | 15/344150 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/68 (20130101) C12Q 2563/107 (20130101) C12Q 2563/155 (20130101) Enzymes C12Y 113/12007 (20130101) C12Y 302/01023 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/54346 (20130101) Original (OR) Class G01N 2021/6421 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977029 | Moller |
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FUNDED BY |
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APPLICANT(S) | David R. Moller (Ellicott City, Maryland) |
ASSIGNEE(S) | |
INVENTOR(S) | David R. Moller (Ellicott City, Maryland) |
ABSTRACT | Sarcoidosis is a multisystem disease characterized by granulomatous inflammation in affected organs. The present invention discloses kits and a system for a blood test using mycobacterial catalase-peroxidase that has a high positive predictive value for confirming a diagnosis of sarcoidosis. |
FILED | Tuesday, November 10, 2015 |
APPL NO | 14/937423 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6866 (20130101) Original (OR) Class G01N 2333/57 (20130101) G01N 2800/24 (20130101) G01N 2800/7095 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977033 | Kumar et al. |
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FUNDED BY |
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APPLICANT(S) | Addanki Pratap Kumar (San Antonio, Texas); Izhar Singh Batth (San Antonio, Texas); Rita Ghosh (San Antonio, Texas); Roble Bedolla (San Antonio, Texas); Ian M. Thompson, Jr. (San Antonio, Texas) |
ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Addanki Pratap Kumar (San Antonio, Texas); Izhar Singh Batth (San Antonio, Texas); Rita Ghosh (San Antonio, Texas); Roble Bedolla (San Antonio, Texas); Ian M. Thompson, Jr. (San Antonio, Texas) |
ABSTRACT | Certain embodiments are directed to methods of identifying a subject having a higher risk of prostate cancer recurrence. The methods can include the step of measuring levels of one or more of FLIP, transcription factor Sp1, and transcription factor Sp3 in a prostate sample from the subject, wherein elevated levels of FLIP, transcription factor Sp1, and transcription factor Sp3 identify a subject as high risk for prostate cancer recurrence. |
FILED | Wednesday, September 11, 2013 |
APPL NO | 14/024348 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/137 (20130101) A61K 31/337 (20130101) A61K 31/573 (20130101) A61K 39/0011 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 33/57434 (20130101) G01N 2333/4706 (20130101) G01N 2800/54 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977035 | Smith |
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FUNDED BY |
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APPLICANT(S) | Ann Smith (Kansas City, Missouri) |
ASSIGNEE(S) | |
INVENTOR(S) | Ann Smith (Kansas City, Missouri) |
ABSTRACT | A method of detecting and measuring the level of total hemopexin and nitrated hemopexin in a sample of a patient in need thereof. The method uses an ELISA for total and nitrated hemopexin. |
FILED | Monday, December 07, 2015 |
APPL NO | 14/961144 |
ART UNIT | 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2800/22 (20130101) G01N 2800/26 (20130101) G01N 2800/2871 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977036 | Schutzer |
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FUNDED BY |
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APPLICANT(S) | Steven E. Schutzer (Water Mill, New York) |
ASSIGNEE(S) | Steven E. Schutzer (New York, New York) |
INVENTOR(S) | Steven E. Schutzer (Water Mill, New York) |
ABSTRACT | Biomarkers and uses thereof, as well as methods for using same for diagnosing first-attack multiple sclerosis are described herein. |
FILED | Friday, August 15, 2014 |
APPL NO | 14/911289 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/136 (20130101) A61K 31/137 (20130101) A61K 31/225 (20130101) A61K 31/277 (20130101) A61K 38/02 (20130101) A61K 38/215 (20130101) Peptides C07K 16/2839 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2333/485 (20130101) G01N 2333/705 (20130101) G01N 2800/285 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977136 | Barrett et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona); inviCRO, LLC (Boston, Massachusetts) |
ASSIGNEE(S) | The Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona); inviCRO, LLC (Boston, Massachusetts) |
INVENTOR(S) | Harrison H. Barrett (Tucson, Arizona); Brian Miller (Tucson, Arizona); Yijun Ding (Aurora, Colorado); Liying Chen (Redmond, Washington); John William Hoppin (Boston, Massachusetts); Luca Caucci (Tucson, Arizona) |
ABSTRACT | The present invention provides methods and systems for 3D imaging of in vivo and ex vivo tissues. The disclosed systems and methods employ an autoradiographic approach where particles emitted by a radioactive composition within the tissue are detected. Once detected, a 3D representation of the source of particles within the tissue is reconstructed for viewing and analysis. |
FILED | Tuesday, October 10, 2017 |
APPL NO | 15/729428 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) A61B 6/4258 (20130101) A61B 6/5205 (20130101) Measurement of Nuclear or X-radiation G01T 1/161 (20130101) G01T 1/2942 (20130101) Original (OR) Class G01T 1/2985 (20130101) G01T 5/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977870 | Hanina et al. |
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FUNDED BY |
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APPLICANT(S) | AIC Innovations Group, Inc. (New York, New York) |
ASSIGNEE(S) | AIC Innovations Group, Inc. (New York, New York) |
INVENTOR(S) | Adam Hanina (New York, New York); Gordon Kessler (Mt. Kisco, New York); Lei Guan (Harrison, New Jersey) |
ABSTRACT | A medication management system is described that is operable to determine whether a user is actually following a protocol, provide additional assistance to a user, starting with instructions, video instructions, and the like, and moving up to contact from a medication administrator if it is determined that the user would need such assistance in any medical adherence situation, including clinical trial settings, home care settings, healthcare administration locations, such as nursing homes, clinics, hospitals and the like. Suspicious activity on the part of a patient or other user of the system is identified and can be noted to a healthcare provider or other service provider where appropriate. |
FILED | Friday, June 09, 2017 |
APPL NO | 15/618944 |
ART UNIT | 2487 — Recording and Compression |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1128 (20130101) A61B 5/4833 (20130101) Electric Digital Data Processing G06F 19/3456 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00 (20130101) G06K 9/00771 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/22 (20130101) Pictorial Communication, e.g Television H04N 7/183 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978159 | Kraus et al. |
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FUNDED BY |
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APPLICANT(S) | Friedrich-Alexander-Universitaet Erlangen-Nuernberg (Erlangen, Germany); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Friedrich-Alexander-Universitaet Erlangen-Nuernberg (Erlangen, Germany) |
INVENTOR(S) | Martin F. G. Kraus (Cambridge, Massachusetts); Benjamin M. Potsaid (Cambridge, Massachusetts); James G. Fujimoto (Cambridge, Massachusetts); Markus Anton Mayer (Cambridge, Massachusetts); Ruediger Bock (Cambridge, Massachusetts); Joachim Hornegger (Cambridge, Massachusetts) |
ABSTRACT | Images of an object, such as OCT scans of a human eye, can include distortions and data gaps due to relative motion of the object and the image acquisition device. Methods and systems for correction of such distortions and data gaps are described herein. Motion-corrected data is arrived at by applying three-dimensional transforms to input three-dimensional data sets that represent at least partially overlapping regions of the imaged object. The three dimensional transforms are computed based on an objective function that accounts for similarity between the transformed three-dimensional data sets and the estimated motion of the object relative to an imaging instrument. Methods and systems described herein advantageously eliminate the need for postulated assumptions and reliance on landmarks and are capable of filling data gaps, thereby producing high quality, undistorted images of objects subject to movement during imaging. Multiple motion-corrected data sets can be merged or combined to produce a data set with improved image quality. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/980466 |
ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/102 (20130101) Image Data Processing or Generation, in General G06T 7/30 (20170101) G06T 7/248 (20170101) G06T 11/006 (20130101) Original (OR) Class G06T 2207/10101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979284 | Jung et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Wanyeong Jung (Ann Arbor, Michigan); Sechang Oh (Ann Arbor, Michigan); Suyoung Bang (Ann Arbor, Michigan); Yoonmyung Lee (Ann Arbor, Michigan); Dennis Sylvester (Ann Arbor, Michigan); David T. Blaauw (Ann Arbor, Michigan) |
ABSTRACT | A self-oscillating DC-DC converter structure is proposed in which an oscillator is completely internalized within the switched-capacitor network. This eliminates power overhead of clock generation and level shifting and enables higher efficiency at lower power levels. Voltage doublers are cascaded to form a complete energy harvester with a wide load range from 5 nW to 5 μW and self-starting operation down to 140 mV. Because each doubler is self-oscillating, the frequency of each stage can be independently modulated, thereby optimizing the overall conversion efficiency. |
FILED | Thursday, February 05, 2015 |
APPL NO | 15/116072 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/36 (20130101) H02M 3/07 (20130101) Original (OR) Class Pulse Technique H03K 3/0315 (20130101) H03K 19/017509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 09974463 | Rutkove et al. |
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FUNDED BY |
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APPLICANT(S) | Seward B. Rutkove (Brookline, Massachusetts); Joel L. Dawson (Roslindale, Massachusetts) |
ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Seward B. Rutkove (Brookline, Massachusetts); Joel L. Dawson (Roslindale, Massachusetts) |
ABSTRACT | A device for determining muscle condition of a region of tissue. The device comprises an electrical impedance myography (EIM) portable probe bearing an electrode array. The electrode array comprises excitation electrodes used to apply multi-frequency electrical signals to the region of tissue and pickup electrodes that are used to collect electrical signals resulting from the application of the multi-frequency electrical signals to the region of tissue. To improve accuracy and reproducibility of EIM measurements, the electrode array is reconfigurable to select different subsets of excitation and pickup electrodes so that the electrodes are oriented differently with respect to muscle fibers. Additional devices may be associated with the EIM probe to measure such parameters as temperature, moisture content of the region, quality of contact of electrodes of the electrode array with a surface of the region and pressure with which the EEM probe is applied to the region. The EIM measurements may be adjusted based on these parameters. Also, ultrasound and electrical impedance tomography measurements may supplement the ELM measurements for more complete analysis of the muscle condition. |
FILED | Friday, August 20, 2010 |
APPL NO | 13/391484 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/053 (20130101) Original (OR) Class A61B 5/0536 (20130101) A61B 5/0537 (20130101) A61B 5/4519 (20130101) A61B 5/6843 (20130101) A61B 2560/0252 (20130101) A61B 2560/0276 (20130101) A61B 2562/046 (20130101) A61B 2562/0209 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974646 | Parel et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
INVENTOR(S) | Jean-Marie Parel (Miami Shores, Florida); Yoh Sawatari (Coral Gables, Florida); Victor L. Perez (Miami, Florida); Andres Bernal (Sunny Isles Beach, Florida) |
ABSTRACT | A keratoprosthesis and system and method of using same for corneal repair. The keratoprosthesis comprises a biocompatible support and an optic member disposed through a channel within the support. The support includes metal, preferably titanium, and treated, such as by sandblasting and/or acid etching, to create textured surfaces that promote soft tissue adhesion. A locking member interconnects the optic member and support. An outer surface of the locking member a collar extending from the support and disposed around the optic member is also metal, preferably titanium, and is similarly treated to promote soft tissue adhesion. A locking member interconnects the optic member and support. The system includes the keratoprosthesis positioned within an isolated soft tissue segment of a non-ocular tissue, such as buccal mucosa, placed on the anterior cornea. The method includes removing corneal epithelium, isolating and transplanting a segment of soft tissue to the de-epithelialized cornea, creating a receiving area in the soft tissue, positioning a keratoprosthesis relative to the receiving area anterior to the cornea, and securing the keratoprosthesis. |
FILED | Wednesday, September 04, 2013 |
APPL NO | 14/426195 |
ART UNIT | 3738 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/142 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974870 | Achilefu et al. |
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FUNDED BY |
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APPLICANT(S) | Washington University (St. Louis, Missouri) |
ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
INVENTOR(S) | Samuel Achilefu (St. Louis, Missouri); Kvar Black (St. Louis, Missouri) |
ABSTRACT | The present invention encompasses compositions comprising two spectrally distinct radionuclides separated by a site susceptible to cleavage. Compositions of the invention may be used to detect enzyme activity and/or image diseases associated with said enzyme activity. |
FILED | Tuesday, June 09, 2015 |
APPL NO | 14/734761 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/088 (20130101) Original (OR) Class A61K 51/1251 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974957 | Choi et al. |
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FUNDED BY |
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APPLICANT(S) | RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
INVENTOR(S) | John S. Choi (Brooklyn, New York); Joseph T. Francis (Brookyn, New York) |
ABSTRACT | Sensory information can be delivered to a subject mammal, for example, for restoring a sense of cutaneous touch and limb motion to the subject mammal. A biomimetic electrical signal is generated based on (a) a stimulation reference signal applied to a somatosensory region of a nervous system of a reference mammal, (b) a stimulated-response signal acquired from a sensory cortex of the reference mammal in response to application of the stimulation reference signal to the thalamic nucleus, and (c) a natural-response signal acquired from the sensory cortex in response to peripheral touch stimuli and/or peripheral nerve stimulation of the reference mammal. The biomimetic electrical signal is applied to a somatosensory region of a nervous system of the subject mammal to induce an activation response, in a sensory cortex of the subject mammal. |
FILED | Tuesday, April 14, 2015 |
APPL NO | 15/304305 |
ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/685 (20130101) A61B 5/4064 (20130101) A61B 5/4827 (20130101) A61B 5/7267 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) A61B 2562/046 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2002/5058 (20130101) A61F 2002/5061 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/0534 (20130101) A61N 1/0551 (20130101) A61N 1/36003 (20130101) A61N 1/36103 (20130101) Original (OR) Class A61N 1/36139 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975135 | Hertel, III et al. |
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FUNDED BY |
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APPLICANT(S) | William M. Hertel, III (Annapolis, Maryland); Richard J. Norcross (Darnestown, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | William M. Hertel, III (Annapolis, Maryland); Richard J. Norcross (Darnestown, Maryland) |
ABSTRACT | The invention is directed to a lightweight apparatus for the redirection and capture of paint overspray and airborne particulates at a surface being painted. The apparatus has a top tubing arrangement, and a bottom tubing arrangement, and blowers that provide air to both tubing arrangements. The invention also has an enclosure having a top opening and a bottom opening. The bottom tubing arrangement is positioned at the bottom opening. The bottom tubing arrangement includes a plurality of perforations creating an airflow that provides a pneumatic seal between the apparatus and the surface being painted, preventing the escape of paint overspray. The top tubing arrangement also includes a plurality of perforations that create an airflow that prevents the escape of paint overspray from the enclosure. Entrained paint overspray and airborne particles within the enclosure are captured by a filter within the enclosure. |
FILED | Friday, November 18, 2016 |
APPL NO | 15/356417 |
ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 15/1214 (20130101) B05B 15/1229 (20130101) Original (OR) Class B05B 15/1248 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975576 | Flaxman |
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FUNDED BY |
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APPLICANT(S) | QINETIQ LIMITED (Farnborough, United Kingdom) |
ASSIGNEE(S) | QINETIQ LIMITED (Hampshire, United Kingdom) |
INVENTOR(S) | Robert John Bonner Flaxman (Guildford, United Kingdom) |
ABSTRACT | Some embodiments are directed to a controlled differential adapted to couple two shafts and steer input, such as those provided in a drive configuration for a skid steered vehicle, the controlled differential including a pair of planet carriers arranged to turn with respective shafts; a pair of ring gears interconnected by a cross-shaft such that the ring gears rotate in common; planet gears and a pair of sun gears, the sun gears being coupled to at least one steer motor to enable rotation of the sun gears in mutually opposite senses upon input from the steer motor. |
FILED | Friday, April 25, 2014 |
APPL NO | 14/896660 |
ART UNIT | 3659 — Material and Article Handling |
CURRENT CPC | Motor Vehicles; Trailers B62D 11/04 (20130101) Original (OR) Class B62D 11/14 (20130101) B62D 55/08 (20130101) Gearing F16H 48/36 (20130101) F16H 2048/364 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975916 | Yin et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Peng Yin (Brookline, Massachusetts); Diming Wei (Cambridge, Massachusetts); Mingjie Dai (Boston, Massachusetts); Cameron Myhrvold (Cambridge, Massachusetts); Yonggang Ke (Atlanta, Georgia); Ralf Jungmann (Cambridge, Massachusetts) |
ABSTRACT | The invention provides SST motifs of controlled size and shape, comprised of a plurality of oligonucleotides, and methods for their synthesis. The motifs are formed, at least in part, by the self-assembly of single stranded oligonucleotides into curved, corrugated or twisted structures. The location of each oligonucleotide in the resultant motif is known. Accordingly, the motifs may be modified with specificity. |
FILED | Wednesday, November 06, 2013 |
APPL NO | 14/440907 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 21/04 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1031 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976130 | Guelta et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Mark A Guelta (White Marsh, Maryland); Melissa M. Dixon (Abingdon, Maryland); Steven P. Harvey (Lutherville, Maryland) |
ABSTRACT | This invention is directed toward a non-wild-type organophosphorus acid anhydrolase enzyme having two site mutations, method of production, and method of use to more effectively degrade toxic organophosphorus compounds and, in particular, toxic chemical GD (3,3-Dimethylbutan-2-ylmethylphosphonofluoridate), than the wild type organophosphorus acid anhydrolase. |
FILED | Friday, December 30, 2016 |
APPL NO | 15/395412 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/465 (20130101) Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/02 (20130101) A62D 2101/02 (20130101) A62D 2101/04 (20130101) A62D 2101/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/08002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976423 | Quach et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | San Quach (East Hartford, Connecticut); Christopher King (Bristol, Connecticut); Steven Bruce Gautschi (Naugatuck, Connecticut); David J. Candelori (Glastonbury, Connecticut) |
ABSTRACT | The systems and methods described herein adapt the orientation, position and/or diffusion angles of showerhead cooling holes depending on the external gas/streamline flow direction. In regions, for example, where the stagnation line is on the pressure side, the breakouts of the showerhead holes substantially face aft (e.g., primarily towards the suction side). The location and positioning of the holes may be oriented according to the direction of incoming gas flows. |
FILED | Wednesday, September 23, 2015 |
APPL NO | 14/862422 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/141 (20130101) F01D 5/186 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/303 (20130101) F05D 2240/305 (20130101) F05D 2240/306 (20130101) F05D 2250/324 (20130101) F05D 2260/202 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/671 (20130101) Y02T 50/673 (20130101) Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976435 | Borja et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Mark Borja (Palm Beach Gardens, Florida); Paul W. Palmer (S. Glastonbury, Connecticut) |
ABSTRACT | A rotating blade tip clearance system includes a control ring carrier defining a centerline axis. The control ring carrier has a connecting portion, a retaining portion radially inward of the connecting portion, and a flange connecting radially between the connecting portion and the retaining portion. The flange isolates the retaining portion of the control ring carrier from the thermal deflection of a case and assists in keeping the control ring carrier aligned about centerline axis A during thermal deflection. The retaining portion includes radially inner and outer diameter sides defining a retaining cavity therebetween. The system includes a control ring within the retaining cavity. The control ring has a different thermal response rate from the control ring carrier so that the control ring thermally deflects slower than the control ring carrier, thereby controlling the rate and/or extent of thermal deflection of the control ring carrier. |
FILED | Thursday, October 15, 2015 |
APPL NO | 14/884015 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 11/18 (20130101) Original (OR) Class F01D 25/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/21 (20130101) F05D 2230/22 (20130101) F05D 2230/30 (20130101) F05D 2240/24 (20130101) F05D 2240/307 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976839 | Rastegar et al. |
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FUNDED BY |
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APPLICANT(S) | Jahangir S Rastegar (Stony Brook, New York); Richard T Murray (Patchogue, New York) |
ASSIGNEE(S) | OMNITEK PARTNERS LLC (Ronkonkoma, New York) |
INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York); Richard T Murray (Patchogue, New York) |
ABSTRACT | A method for generating power in a gravity dropped munition. The method including: attaching a cable from a generator associated with the munition to a portion of an aircraft; separating the munition from the aircraft to pull the cable from the munition; converting the pulling of the cable to a rotation; producing power from the rotation; and providing the power to an internal component of the munition. |
FILED | Friday, July 01, 2016 |
APPL NO | 15/201101 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 25/00 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 11/02 (20130101) F42C 11/008 (20130101) Original (OR) Class F42C 15/40 (20130101) Dynamo-electric Machines H02K 7/108 (20130101) H02K 7/116 (20130101) H02K 7/1807 (20130101) H02K 7/1853 (20130101) Electric Machines Not Otherwise Provided for H02N 2/18 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977046 | Swanson et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
INVENTOR(S) | Paul D. Swanson (San Diego, California); Andrew Wang (San Diego, California); Charles H. Tally, IV (San Diego, California) |
ABSTRACT | A device includes two electrically isolated metalized posts attached in close proximity to each other on a bendable substrate. When the bendable substrate bends concavely with respect to the surface onto which the posts are mounted, the distance between the tops of the two posts decreases. At a fixed bending curvature, the two posts will meet and complete an electrical circuit. The posts comprise a flexible material so that the meeting of the posts has minimal effect on the spring constant or damping coefficient of the harmonic oscillation. |
FILED | Monday, August 08, 2016 |
APPL NO | 15/231662 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/16 (20130101) G01P 15/097 (20130101) G01P 15/135 (20130101) Original (OR) Class G01P 15/0802 (20130101) G01P 2015/0805 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977123 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Lingji Chen (Acton, Massachusetts); Balasubramaniam Ravichandran (Winchester, Massachusetts) |
ABSTRACT | A system and method for projecting target tracks produced by a remote tracker onto a surface of the Earth to obtain projected tracks is provided. Projection bias in a projected track from the remote tracker projected onto a planar map is removed by computing a discrete Frechet distance from a polygonal curve associated with a track derived from the remote tracker to a corresponding polygonal curve on the planar map. A correspondence between the projected track and a track on the planar map is automatically established. A projection bias is removed based on the correspondence. |
FILED | Wednesday, April 29, 2015 |
APPL NO | 14/699645 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/04 (20130101) G01S 13/723 (20130101) G01S 13/867 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977489 | Kelly et al. |
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FUNDED BY |
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APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
ASSIGNEE(S) | WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia) |
INVENTOR(S) | Brandon Michael Kelly (Morgantown, West Virginia); Brandon David Rumberg (Beckley, West Virginia); David W. Graham (Morgantown, West Virginia) |
ABSTRACT | Aspects of a low power memory buffer are described. In one embodiment, a sampling rate of a signal is adjusted to identify extrema of a signal. An extrema pulse is generated and, in response to the extrema pulse, a time segment and potential value of the signal are stored in a memory. In other aspects, rising and falling slopes of the signal are tracked to identify a local maximum and a local minimum of the signal. In this scenario, an extrema pulse is generated for each of the local maximum and minimum, and time segment and potential values are stored for the local maximum and minimum. Generally, the storage of analog values of the signal at an adjusted sampling rate is achieved with low power, and the signal may be reconstructed at a later time. |
FILED | Tuesday, May 17, 2016 |
APPL NO | 15/156670 |
ART UNIT | 2118 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/08 (20130101) G06F 1/10 (20130101) G06F 1/3203 (20130101) G06F 1/3275 (20130101) G06F 1/3293 (20130101) Original (OR) Class G06F 3/05 (20130101) G06F 9/4418 (20130101) G06F 13/24 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0816 (20130101) Wireless Communication Networks H04W 52/02 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/14 (20180101) Y02D 70/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977652 | Wadden et al. |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | John Pierson Wadden (Charlottesville, Virginia); Nathan James Brunelle (Charlottesville, Virginia) |
ABSTRACT | Disclosed embodiments include systems, methods, and computer-readable media for generating pseudo-random numbers. Disclosed embodiments may receive, by the at least one processor, range data indicating a range of numbers. Disclosed embodiments may generate, based on the range data and by the at least one processor, a digitized finite state machine configured to produce pseudo-random output within the range of numbers. Further, disclosed embodiments may provide, by the at least one processor to a specialized pattern-matching device, programmable instructions to implement the digitized finite state machine on the specialized pattern-matching device. Disclosed embodiments may transmit, by the at least one processor to the specialized pattern-matching device, a pseudo-random bit stream for processing by the digitized finite state machine. Disclosed embodiments may receive, by the at least one processor from the specialized pattern-matching device, pseudo-random output from the digitized finite state machine. |
FILED | Wednesday, April 06, 2016 |
APPL NO | 15/091925 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 7/584 (20130101) Original (OR) Class G06F 2207/583 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977897 | Momot |
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FUNDED BY |
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APPLICANT(S) | Leviathan, Inc. (Seattle, Washington) |
ASSIGNEE(S) | Leviathan Security Group, Inc. (Seattle, Washington) |
INVENTOR(S) | Falcon Momot (Seattle, Washington) |
ABSTRACT | Systems, methods and media are shown for detecting a stack pivot programming exploit that involve extracting return addresses from a call stack from a snapshot of a running program and, for each extracted return address, identifying a stack frame and following frame from stack pointer information, checking whether the stack is consistent with the type of stack generated by the operating system and architecture conventions, and alerting that a stack pivot is likely if an anomaly in stack layout is found. Some examples involve determining whether the stack frame and following frame follow consistently in one of ascending or descending addresses. Some examples involve, given a consistent directional polarity and metadata about the directional polarity of the stack specified by one of the microarchitecture, operating system, software, or other configuration, determining whether the observed directional polarity corresponds to the expected directional polarity. |
FILED | Thursday, July 16, 2015 |
APPL NO | 14/801753 |
ART UNIT | 2498 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/54 (20130101) Original (OR) Class G06F 21/554 (20130101) G06F 2221/033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977904 | Khan et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Latifur Khan (Plano, Texas); Zhiqiang Lin (Dallas, Texas); Bhavani Thuraisingham (Dallas, Texas); Justin Sahs (Richardson, Texas); David Sounthiraraj (Richardson, Texas); Garrett Greenwood (Richardson, Texas) |
ABSTRACT | Disclosed are systems and methods for performing automatic, large-scale analysis mobile applications to determine and analyze application vulnerability. The disclosed systems and methods include identifying potentially vulnerable applications, identifying the application entry points that lead to vulnerable behavior, and generating smart input for text fields. Thus, a fully automated framework is implemented to run in parallel on multiple emulators, while collecting vital information. |
FILED | Tuesday, February 24, 2015 |
APPL NO | 14/629876 |
ART UNIT | 2494 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/033 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) Wireless Communication Networks H04W 88/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977972 | Khan et al. |
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FUNDED BY |
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APPLICANT(S) | SRI International (Menlo Park, California) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Saad Masood Khan (Hamilton, New Jersey); Hui Cheng (Bridgewater, New Jersey); Dennis Lee Matthies (Princeton, New Jersey); Harpreet Singh Sawhney (West Windsor, New Jersey); Sang-Hack Jung (Lawrenceville, New Jersey); Chris Broaddus (Philadelphia, Pennsylvania); Bogdan Calin Mihai Matei (Monmouth Junction, New Jersey); Ajay Divakaran (Monmouth Junction, New Jersey) |
ABSTRACT | A computer implemented method for determining a vehicle type of a vehicle detected in an image is disclosed. An image having a detected vehicle is received. A number of vehicle models having salient feature points is projected on the detected vehicle. A first set of features derived from each of the salient feature locations of the vehicle models is compared to a second set of features derived from corresponding salient feature locations of the detected vehicle to form a set of positive match scores (p-scores) and a set of negative match scores (n-scores). The detected vehicle is classified as one of the vehicle models based at least in part on the set of p-scores and the set of n-scores. |
FILED | Tuesday, October 21, 2014 |
APPL NO | 14/519927 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/123 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/08 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00651 (20130101) G06K 9/00785 (20130101) Original (OR) Class G06K 9/4671 (20130101) G06K 9/6269 (20130101) G06K 9/6282 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/20 (20130101) G06T 2207/10012 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978002 | Schneiderman |
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FUNDED BY |
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APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Henry Schneiderman (Pittsburgh, Pennsylvania) |
ABSTRACT | System and method for determining a classifier to discriminate between two classes—object or non-object. The classifier may be used by an object detection program to detect presence of a 3D object in a 2D image. The overall classifier is constructed of a sequence of classifiers, where each such classifier is based on a ratio of two graphical probability models. A discreet-valued variable representation at each node in a Bayesian network by a two-stage process of tree-structured vector quantization is discussed. The overall classifier may be part of an object detector program that is trained to automatically detect different types of 3D objects. Computationally efficient statistical methods to evaluate overall classifiers are disclosed. The Bayesian network-based classifier may also be used to determine if two observations belong to the same category. |
FILED | Tuesday, November 10, 2015 |
APPL NO | 14/937851 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00228 (20130101) G06K 9/00241 (20130101) G06K 9/00288 (20130101) G06K 9/6227 (20130101) G06K 9/6278 (20130101) Original (OR) Class G06K 9/6282 (20130101) G06K 9/6296 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978015 | Nugent et al. |
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FUNDED BY |
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APPLICANT(S) | KnowmTech, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | KnowmTech, LLC (Santa Fe, New Mexico) |
INVENTOR(S) | Alex Nugent (Sante Fe, New Mexico); Tim Molter (Oberstdorf, Germany) |
ABSTRACT | A thermodynamic RAM apparatus includes a physical substrate of addressable adaptive synapses that are temporarily partitioned to emulate adaptive neurons of arbitrary sizes, wherein the physical substrate mates electronically with a digital computing platform for high-throughput and low-power neuromorphic adaptive learning applications. The physical substrate addressable adaptive synapses can be configured as a part of a memristor-based physical neural processing unit. |
FILED | Tuesday, May 05, 2015 |
APPL NO | 14/704394 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978020 | Gambetta et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Jay M. Gambetta (Yorktown Heights, New York); Easwar Magesan (Yorktown Heights, New York) |
ABSTRACT | A technique relates to quantum error correction. Code qubits are configured as target qubits, and the code qubits have a first dephasing time and a first anharmonicity. Syndrome qubits are configured as control qubits, and the syndrome qubits have a second dephasing time and a second anharmonicity. The target qubits and the control qubits are configured to form one or more controlled not (CNOT) gates. The first dephasing time is greater than the second dephasing time and the second anharmonicity is greater than the first anharmonicity. |
FILED | Wednesday, March 29, 2017 |
APPL NO | 15/473011 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/00 (20130101) G06N 99/002 (20130101) Original (OR) Class Pulse Technique H03K 19/00346 (20130101) Coding; Decoding; Code Conversion in General H03M 13/01 (20130101) H03M 13/005 (20130101) H03M 13/154 (20130101) H03M 13/1575 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978021 | Hoover et al. |
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FUNDED BY |
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APPLICANT(S) | Accenture Global Services Limited (Dublin, Ireland) |
ASSIGNEE(S) | Accenture Global Services Limited (Dublin, Ireland) |
INVENTOR(S) | James Hoover (Mechanicsburg, Pennsylvania); Jeffrey Scott Miller (Fairfax Station, Virginia) |
ABSTRACT | A system for database management and presentation processing of a graphical user interface includes a network interface interfacing with multiple data sources comprising internal systems and external systems, one or more processors, and an application service integration and communication layer to receive data including a live data feed. A data storage device stores schemas of data structures, and the data structures may include tables based on types and fields. The application service integration and communication layer normalizes and formats the live data feed according to the predetermined schemas, and stores the normalized and formatted procurement data in the database. A graphical user interface of true conditions assigned to procurement data in the live data feed is displayed. |
FILED | Wednesday, January 06, 2016 |
APPL NO | 14/989572 |
ART UNIT | 3625 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Electric Digital Data Processing G06F 3/0481 (20130101) G06F 17/30294 (20130101) G06F 17/30401 (20130101) G06F 17/30477 (20130101) G06F 17/30557 (20130101) G06F 17/30572 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 5/045 (20130101) G06N 99/005 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) G06Q 10/0635 (20130101) G06Q 30/06 (20130101) G06Q 30/08 (20130101) G06Q 30/0201 (20130101) G06Q 30/0206 (20130101) G06Q 30/0611 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978149 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Lei Zhang (Torrance, California); Kyungnam Kim (Oak Park, California); Deepak Khosla (Camarillo, California) |
ABSTRACT | Described is a system for door detection for use with an unmanned aerial vehicle (UAV). The system receive a video input image from a single monocular camera. Edge points are detected in the video, with the edge points connected to form long edge lines. Orientations of the long edge lines are determined, such that long edge lines having a substantially vertical orientation are designated as initial door line candidates and long edge lines having a non-vertical, non-horizontal orientation are designated for use in detecting a vanishing point. A vanishing point is then detected in the video frame. Thereafter, intensity profile and line properties of the door line candidates are calculated. Finally, it is verified if the door line candidates are real world door lines and, if so, an area between the real world door lines is designated as an open door. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/981131 |
ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0044 (20130101) Original (OR) Class G06T 7/0061 (20130101) G06T 7/0085 (20130101) G06T 2207/10016 (20130101) G06T 2207/20021 (20130101) G06T 2207/20024 (20130101) G06T 2207/30252 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978159 | Kraus et al. |
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FUNDED BY |
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APPLICANT(S) | Friedrich-Alexander-Universitaet Erlangen-Nuernberg (Erlangen, Germany); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Friedrich-Alexander-Universitaet Erlangen-Nuernberg (Erlangen, Germany) |
INVENTOR(S) | Martin F. G. Kraus (Cambridge, Massachusetts); Benjamin M. Potsaid (Cambridge, Massachusetts); James G. Fujimoto (Cambridge, Massachusetts); Markus Anton Mayer (Cambridge, Massachusetts); Ruediger Bock (Cambridge, Massachusetts); Joachim Hornegger (Cambridge, Massachusetts) |
ABSTRACT | Images of an object, such as OCT scans of a human eye, can include distortions and data gaps due to relative motion of the object and the image acquisition device. Methods and systems for correction of such distortions and data gaps are described herein. Motion-corrected data is arrived at by applying three-dimensional transforms to input three-dimensional data sets that represent at least partially overlapping regions of the imaged object. The three dimensional transforms are computed based on an objective function that accounts for similarity between the transformed three-dimensional data sets and the estimated motion of the object relative to an imaging instrument. Methods and systems described herein advantageously eliminate the need for postulated assumptions and reliance on landmarks and are capable of filling data gaps, thereby producing high quality, undistorted images of objects subject to movement during imaging. Multiple motion-corrected data sets can be merged or combined to produce a data set with improved image quality. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/980466 |
ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/102 (20130101) Image Data Processing or Generation, in General G06T 7/30 (20170101) G06T 7/248 (20170101) G06T 11/006 (20130101) Original (OR) Class G06T 2207/10101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978474 | Yaghi et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Omar M. Yaghi (Berkeley, California); Shun Wan (Santa Monica, California); Christian J. Doonan (Eastwood, Australia); Bo Wang (Beijing, China PRC); Hexiang Deng (Albany, California) |
ABSTRACT | The disclosure relates generally to materials that comprise conductive covalent organic frameworks. The disclosure also relates to materials that are useful to store and separate gas molecules and sensors. |
FILED | Monday, February 22, 2016 |
APPL NO | 15/050136 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) B01J 20/26 (20130101) Heterocyclic Compounds C07D 487/22 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/324 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978832 | Martino |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Christopher Adrian Martino (Arnold, Maryland) |
ABSTRACT | A vertical superjunction edge termination structure for the drift region of wide bandgap semiconductor devices that provides a low resistance and high off voltage allowing the breakdown voltage of the superjunction drift region to be raised. |
FILED | Wednesday, August 23, 2017 |
APPL NO | 15/684359 |
ART UNIT | 2823 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/046 (20130101) H01L 21/0475 (20130101) H01L 29/0634 (20130101) Original (OR) Class H01L 29/1608 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979011 | Atwater et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Terrill B. Atwater (Bel Air, Maryland); Paula C. Latorre (Bel Air, Maryland); Ashley L. Ruth (Bel Air, Maryland) |
ABSTRACT | A method of preparing a homogeneously dispersed chlorine-modified lithium manganese-based AB2O4 spinel cathode material is provided. Furthermore, a homogeneously dispersed chlorine-modified lithium manganese-based AB2O4 spinel cathode material is provided. In addition, a lithium or lithium ion rechargeable electrochemical cell is provided incorporating a homogeneously dispersed chlorine-modified lithium manganese-based AB2O4 spinel cathode material in a positive electrode. |
FILED | Friday, September 26, 2014 |
APPL NO | 14/497620 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/1242 (20130101) C01G 53/54 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/32 (20130101) C01P 2002/72 (20130101) C01P 2002/88 (20130101) C01P 2004/61 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/505 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/1315 (20130101) Original (OR) Class H01M 10/0525 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979053 | Vu et al. |
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FUNDED BY |
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APPLICANT(S) | A123 Systems, LLC (Waltham, Massachusetts) |
ASSIGNEE(S) | A123 Systems, LLC (Waltham, Massachusetts) |
INVENTOR(S) | Viet Vu (Canton, Michigan); Michael R. Wixom (Ann Arbor, Michigan) |
ABSTRACT | A rechargeable, hybrid battery system incorporates a high power battery component and a high energy density battery component. The voltage of the high energy density battery varies as a function of its state of charge, but remains greater than the voltage of the high power battery throughout the operating range of the battery system. |
FILED | Wednesday, December 05, 2012 |
APPL NO | 14/364221 |
ART UNIT | 2851 — Printing/Measuring and Testing |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/525 (20130101) H01M 4/587 (20130101) H01M 4/5825 (20130101) H01M 10/441 (20130101) H01M 10/4207 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0052 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979097 | Nipper |
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FUNDED BY |
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APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Joseph P. Nipper (Allen, Texas) |
ABSTRACT | The present disclosure is directed toward methods for forming an expanding lattice notch array antenna that includes a plurality of notch antenna elements extending from a surface of a base plate. The properties and dimensions of the notch antenna elements can be manipulated in order to provide an expanding notch array antenna whereby an area of a base portion of the array is different from an area of a top portion of the array, without increasing an overall height of the notch array antenna. The method includes coupling a first plurality of notch elements to a first surface of a base plate in a first orientation, expanding a second plurality of notch elements from a first state to a second state and coupling the second plurality of notch elements in the second state to the first surface of the base plate in a second orientation. |
FILED | Wednesday, March 16, 2016 |
APPL NO | 15/071457 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/085 (20130101) H01Q 13/085 (20130101) H01Q 21/24 (20130101) H01Q 21/30 (20130101) Original (OR) Class H01Q 21/064 (20130101) H01Q 21/0087 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979160 | Christodoulides et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
INVENTOR(S) | Demetrios Christodoulides (Orlando, Florida); Patrick L. LiKamWa (Orlando, Florida); Parinaz Aleahmad (Orlando, Florida); Ramy El-Ganainy (Orlando, Florida) |
ABSTRACT | An optical circulator is a device that routes optical pulses from port to port in a predetermined manner, e.g. in a 3-port optical circulator, optical pulses entering port 1 are routed out of port 2, while optical pulses entering port 2 exit out of port 3 and optical pulses fed into port 3 exit out of port 3. Currently such an optical circulator is made of discrete components such as magnetooptic garnets, rare-earth magnets and optical polarizers that are packaged together with fiber optic elements. Disclosed herein is a different kind of optical circulator that is monolithically integrated on a single semiconductor substrate and that is applicable for the routing of optical pulses. The embodied invention will enable photonic integrated circuits to incorporate on-chip optical circulator functionality thereby allowing much more complex optical designs to be implemented monolithically. |
FILED | Tuesday, June 20, 2017 |
APPL NO | 15/627964 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/2746 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/22 (20130101) H01S 5/026 (20130101) H01S 5/1003 (20130101) H01S 5/3054 (20130101) H01S 5/5063 (20130101) H01S 5/34326 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979173 | Benavides |
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FUNDED BY |
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APPLICANT(S) | Nicholas David Benavides (Allison Park, Pennsylvania) |
ASSIGNEE(S) | GE ENERGY POWER CONVERSION TECHNOLOGY LIMITED (Warwickshire, United Kingdom) |
INVENTOR(S) | Nicholas David Benavides (Allison Park, Pennsylvania) |
ABSTRACT | A bus bar assembly includes a first main conductor, a second main conductor, and an insulator member provided between the main conductors. The insulator member includes: (i) an insulator component, (ii) a first conductor layer provided on the top surface of the insulator component, and (iii) a second conductor layer provided on the bottom surface of the insulator component, wherein the first conductor layer includes an outer edge around a perimeter thereof, wherein the outer edge is located at least a certain distance from the outer edge around the perimeter of the insulator component, wherein the second conductor layer includes an outer edge around a perimeter thereof, wherein the outer edge is located at least the same certain distance from the outer edge of the insulator component, and wherein the certain distance is sufficient to cause the bus bar assembly to satisfy the creepage requirement of the assembly. |
FILED | Friday, April 29, 2011 |
APPL NO | 13/097654 |
ART UNIT | 2848 — Electrical Circuits and Systems |
CURRENT CPC | Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 5/005 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/4913 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979372 | Hoppenjans et al. |
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FUNDED BY |
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APPLICANT(S) | Indiana Microelectronics, LLC (West Lafayette, Indiana) |
ASSIGNEE(S) | Indiana Microelectronics, LLC (West Lafayette, Indiana) |
INVENTOR(S) | Eric E. Hoppenjans (West Lafayette, Indiana); Steven J. Cuppy (Monticello, Indiana) |
ABSTRACT | Illustrative embodiments of reconfigurable microwave filters, as well as associated systems and methods, are disclosed. In at least one illustrative embodiment, a reconfigurable microwave filter may comprise a plurality of cavity resonators on a common substrate and a plurality of control circuits each configured to control a resonant frequency of one of the plurality of cavity resonators. The reconfigurable microwave filter may also comprise a plurality of feedback circuits each configured to generate a feedback signal that is indicative of the resonant frequency of one of the plurality of cavity resonators and to transmit the feedback signal to one of the plurality of control circuits. |
FILED | Friday, April 24, 2015 |
APPL NO | 14/695662 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/208 (20130101) H01P 1/2053 (20130101) H01P 7/04 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/004 (20130101) H03H 7/0123 (20130101) H03H 7/0153 (20130101) Original (OR) Class Tuning Resonant Circuits; Selecting Resonant Circuits H03J 1/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979738 | Holland et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Gavin D. Holland (Newbury Park, California); Michael D. Howard (Westlake Village, California); Chong Ding (Riverside, California); Tsai-Ching Lu (Thousand Oaks, California) |
ABSTRACT | Described is a system for detecting attacks on networks. A hierarchical representation of activity of a communication network is used to detect and predict sources of misinformation in the communication network. The hierarchical representation includes temporal patterns of communication between at least one pair of nodes, each temporal pattern representing a motif, having a size, in the hierarchical representation. Changes in motifs provide a signal for a misinformation attack. |
FILED | Friday, March 18, 2016 |
APPL NO | 15/075052 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/145 (20130101) H04L 63/1416 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/10 (20130101) H04W 84/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980088 | Manz et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Paul C. Manz (Andover, New Jersey); Fernando J. Maymi (Aguadilla, Puerto Rico); Manuel Rodriguez-Martinez (Cabo Rojo, Puerto Rico) |
ABSTRACT | A method on a first mobile node for facilitating exchange of pertinent data between mobile nodes over a wireless communications network can be provided. The method can include establishing, by the first mobile node, a wireless network connection with at least one other mobile node inside a predefined geospatial area, wherein the wireless network connection is established over the wireless communications network. The method can further include determining that a future position of the first mobile node is outside the predefined geospatial area and transmitting pertinent data residing on the first mobile node over the wireless communications network exclusively to the at least one other mobile node inside the predefined geospatial area, wherein the pertinent data is associated with the predefined geospatial area. |
FILED | Friday, October 31, 2014 |
APPL NO | 14/529512 |
ART UNIT | 2464 — Multiplex and VoIP |
CURRENT CPC | Transmission H04B 7/14 (20130101) Wireless Communication Networks H04W 4/021 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980361 | McDonald |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Michael S. McDonald (Springfield, Virginia) |
ABSTRACT | Embodiments relate to a hallow cathode with integral layers of radiation shielding. The hollow cathode includes an inner cathode tube that forms a gas feed to direct gas toward a downstream end, where the directed gas forms plasma. A heater element is positioned at the downstream end of the inner cathode tube, the heater element to heat the plasma. The hollow cathode further includes an outer cathode tube with a keeper electrode to sustain a bias voltage across a gap at a downstream end of the outer cathode tube for igniting the plasma. The integral layers of radiation shielding are connected by offset radial supports and are incorporated as a single element with either the inner or outer cathode tube, where the integral layers are nested with torturous conductive paths to reduce radiation and conduction losses from the downstream end of the inner cathode tube. |
FILED | Friday, June 16, 2017 |
APPL NO | 15/625898 |
ART UNIT | 2879 — Optics |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/405 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0075 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 09975080 | Luebke et al. |
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FUNDED BY |
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APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | David Luebke (Bethel Park, Pennsylvania); Hunaid Nulwala (Pittsburgh, Pennsylvania); Brian Kail (Pittsburgh, Pennsylvania); Fan Shi (Pittsburgh, Pennsylvania); Robert L Thompson (Pittsburgh, Pennsylvania); Nicholas Siefert (Jefferson Hills, Pennsylvania) |
ABSTRACT | Exemplary embodiments relate to methods for removal of CO2 and other acid gases from gaseous fuels prior to combustion. Exemplary methods may be used for CO2 capture, H2 purification and natural gas sweetening. Exemplary methods use at least one ionic liquid that has excellent CO2 solubility, selectivity over hydrogen, low viscosity, and resistance to H2S. |
FILED | Tuesday, February 16, 2016 |
APPL NO | 15/045201 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/1425 (20130101) B01D 53/1475 (20130101) Original (OR) Class B01D 53/1493 (20130101) B01D 2252/30 (20130101) B01D 2252/2053 (20130101) B01D 2252/2056 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/005 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/104 (20130101) C10L 2290/12 (20130101) C10L 2290/541 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975178 | Qian et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Fang Qian (Santa Cruz, California); Eric Duoss (Dublin, California); Jinkyu Han (San Ramon, California); Thomas Han (Livermore, California); Joshua Kuntz (Livermore, California); Pui Ching Lan (Sacramento, California); Tammy Olson (Livermore, California); Christopher Spadaccini (Oakland, California); Marcus A. Worsley (Hayward, California); Cheng Zhu (Livermore, California) |
ABSTRACT | In one embodiment, a process includes creating a mixture of an aqueous component, nanowires and nanoparticles, and a hydrophobic solvent and allowing migration of the nanowires to the hydrophobic solvent, where the nanoparticles remain in the aqueous component. Moreover, the nanowires and nanoparticles are in the aqueous component before the migration. |
FILED | Friday, July 15, 2016 |
APPL NO | 15/212100 |
ART UNIT | 3653 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Flotation; Differential Sedimentation B03D 1/00 (20130101) B03D 3/00 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0025 (20130101) Original (OR) Class B22F 9/24 (20130101) B22F 2009/245 (20130101) B22F 2301/10 (20130101) B22F 2998/10 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975768 | Varma et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Arvind Varma (West Lafayette, Indiana); Hyun Tae Hwang (West Lafayette, Indiana); Ahmad Al-Kukhun (Hillsboro, Oregon) |
ABSTRACT | A system for generating and purifying hydrogen. To generate hydrogen, the system includes inlets configured to receive a hydrogen carrier and an inert insulator, a mixing chamber configured to combine the hydrogen carrier and the inert insulator, a heat exchanger configured to apply heat to the mixture of hydrogen carrier and the inert insulator, wherein the applied heat results in the generation of hydrogen from the hydrogen carrier, and an outlet configured to release the generated hydrogen. To purify hydrogen, the system includes a primary inlet to receive a starting material and an ammonia filtration subassembly, which may include an absorption column configured to absorb the ammonia into water for providing purified hydrogen at a first purity level. The ammonia filtration subassembly may also include an adsorbent member configured to adsorb ammonia from the starting material into an adsorbent for providing purified hydrogen at a second purity level. |
FILED | Thursday, August 04, 2016 |
APPL NO | 15/228384 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 53/02 (20130101) B01D 53/18 (20130101) B01D 53/1418 (20130101) B01D 53/1493 (20130101) B01D 2252/103 (20130101) B01D 2257/406 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/04 (20130101) C01B 3/047 (20130101) C01B 3/52 (20130101) Original (OR) Class C01B 2203/066 (20130101) C01B 2203/0272 (20130101) C01B 2203/0277 (20130101) C01B 2203/0415 (20130101) C01B 2203/0465 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0606 (20130101) H01M 8/0662 (20130101) H01M 8/0687 (20130101) H01M 8/04067 (20130101) H01M 8/04164 (20130101) H01M 8/04291 (20130101) H01M 2008/1095 (20130101) H01M 2300/0082 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Y02E 60/364 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975804 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Jie Li (Darien, Illinois); Yugang Sun (Naperville, Illinois); Ralph T. Muehleisen (Oak Park, Illinois); Leah B. Guzowski (Chicago, Illinois); Xiaojie Yan (Darien, Illinois); Samuel Dull (Lemont, Illinois); Ioannina Castano (Lemont, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Jie Li (Darien, Illinois); Yugang Sun (Naperville, Illinois); Ralph T. Muehleisen (Oak Park, Illinois); Leah B. Guzowski (Chicago, Illinois); Xiaojie Yan (Darien, Illinois); Samuel Dull (Lemont, Illinois); Ioannina Castano (Lemont, Illinois) |
ABSTRACT | The invention provides a method for producing composite nanoparticles, the method using a first compound capable of transitioning from a monoclinic to a tetragonal rutile crystal state upon heating, and having the steps of subjecting the first compound to a hydrothermal synthesis to create anisotropic crystals of the compound; encapsulating the first compound with a second compound to create a core-shell construct; and annealing the construct as needed. Also provided is a device for continuously synthesizing composite nanoparticles, the device having a first precursor supply and a second precursor supply; a mixer to homogeneously combine the first precursor and second precursor to create a liquor; a first microreactor to subject the liquor to hydrothermic conditions to create an\isotropic particles in a continuous operation mode; and a second microreactor for coating the particles with a third precursor to create a core-shell construct. |
FILED | Thursday, April 13, 2017 |
APPL NO | 15/487276 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 25/02 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 1/02 (20130101) C03C 1/10 (20130101) C03C 3/04 (20130101) C03C 4/02 (20130101) Original (OR) Class C03C 2204/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976058 | Solberg |
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FUNDED BY |
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APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Scott Eugene Solberg (San Jose, California) |
ABSTRACT | The disclosure relates to sealant compositions for forming hermetic seals, methods of use, and hermetically sealed products. The sealant compositions comprise a first inorganic oxide chosen from at least one of MgSiO3, MgO, MgTiO3, CaO, and CaSiO3, a second inorganic oxide chosen from SiO2, at least one solvent, and optionally at least one organic resin binder. |
FILED | Friday, May 29, 2015 |
APPL NO | 14/725780 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 51/02 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 53/06 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 8/24 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 37/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 1/00 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/1003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976137 | Scheinberg et al. |
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FUNDED BY |
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APPLICANT(S) | David A. Scheinberg (New York, New York); Michael R. McDevitt (Bronx, New York); Carlos H. Villa (Philadelphia, Pennsylvania); J. Justin Mulvey (New York, New York) |
ASSIGNEE(S) | |
INVENTOR(S) | David A. Scheinberg (New York, New York); Michael R. McDevitt (Bronx, New York); Carlos H. Villa (Philadelphia, Pennsylvania); J. Justin Mulvey (New York, New York) |
ABSTRACT | Provided herein are methods for delivering a molecule in situ to a cell and for treating a cancer via the in situ delivery. The methods comprise contacting or administering to the cell, as two separate components, a morpholino oligonucleotide comprising a targeting moiety followed by a single wall nanotube construct comprising second morpholino oligonucleotides complementary to the first morpholino oligonucleotides and one or both of a therapeutic or diagnostic payload molecule linked to the single wall nanotube construct. Upon self-assembly of a single wall nanotube complex via hybridization of the first morpholino and second complementary morpholino oligonucleotides at the cell, the payload molecule is delivered. Also provided is the two component self-assembly single wall nanotube system and the single wall nanotube construct comprising the second component. |
FILED | Friday, June 27, 2014 |
APPL NO | 14/318112 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 51/1027 (20130101) A61K 51/1093 (20130101) A61K 51/1203 (20130101) A61K 51/1248 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/351 (20130101) C12N 2310/3233 (20130101) C12N 2320/32 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/842 (20130101) Y10S 977/906 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976155 | Shanklin et al. |
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FUNDED BY |
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APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York); Dow AgroSciences LLC (Indianapolis, Indiana) |
ASSIGNEE(S) | Dow AgroSciences LLC (Indianapolis, Indiana); Brookhaven Science Associates, LLC (Upton, New York) |
INVENTOR(S) | John Shanklin (Shoreham, New York); Tam Huu Nguyen (Lincoln, Nebraska); Terence A. Walsh (Zionsville, Indiana); Mark S. Pidkowich (British Colombia, Canada); Edward J. Whittle (Greenport, New York) |
ABSTRACT | Compositions and methods include genetically encoding and expressing a novel Δ9-18:0-ACP desaturase in plant cells. In some embodiments, nucleic acid molecules encode the novel Δ9-18:0-ACP desaturase. In other embodiments, amino acid sequences have Δ9-18:0-ACP desaturase activity. Methods can involve expression of Δ9-18:0-ACP desaturase in plant cells, plant materials, and whole plants for the purpose of increasing the amount of unusual fatty acids in whole plants, plant seeds, and plant materials, for example, seeds. |
FILED | Friday, April 15, 2016 |
APPL NO | 15/130788 |
ART UNIT | 1663 — Plants |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) C12N 9/0083 (20130101) C12N 15/8247 (20130101) Original (OR) Class Enzymes C12Y 114/19001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976199 | Kuttiyiel et al. |
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FUNDED BY |
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APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
INVENTOR(S) | Kurian A. Kuttiyiel (New Hyde Park, New York); Kotaro Sasaki (Hauppauge, New York); Radoslav R. Adzic (East Setauket, New York) |
ABSTRACT | Embodiments of the disclosure relate to intermetallic nanoparticles. Embodiments include nanoparticles having an intermetallic core including a first metal and a second metal. The first metal may be palladium and the second metal may be at least one of cobalt, iron, nickel, or a combination thereof. The nanoparticles may further have a shell that includes palladium and gold. |
FILED | Wednesday, April 22, 2015 |
APPL NO | 15/305123 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/8913 (20130101) B01J 35/006 (20130101) B01J 35/008 (20130101) B01J 35/0013 (20130101) B01J 35/0033 (20130101) B01J 37/16 (20130101) B01J 2523/00 (20130101) B01J 2523/00 (20130101) B01J 2523/19 (20130101) B01J 2523/824 (20130101) B01J 2523/845 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/025 (20130101) B22F 9/24 (20130101) Alloys C22C 1/0491 (20130101) C22C 5/04 (20130101) Original (OR) Class C22C 19/07 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/921 (20130101) H01M 4/9041 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976220 | Hu et al. |
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FUNDED BY |
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APPLICANT(S) | The California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Shu Hu (Pasadena, California); Nathan S. Lewis (La Canada Flintridge, California) |
ABSTRACT | A photoanode includes a passivation layer on a light absorber. The passivation layer is more resistant to corrosion than the light absorber. The photoanode includes a surface modifying layer that is location on the passivation layer such that the passivation layer is between the light absorber and the surface modifying layer. The surface modifying layer reduces a resistance of the passivation layer to conduction of holes out of the passivation layer. |
FILED | Friday, October 10, 2014 |
APPL NO | 14/512248 |
ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/003 (20130101) Original (OR) Class C25B 11/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976360 | Wassell et al. |
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FUNDED BY |
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APPLICANT(S) | Mark Ellsworth Wassell (Houston, Texas); Daniel E. Burgess (Portland, Connecticut); Jason R. Barbely (East Islip, New York); Fred Lamar Thompson (Somers, Connecticut) |
ASSIGNEE(S) | APS TECHNOLOGY, INC. (Wallingford, Connecticut) |
INVENTOR(S) | Mark Ellsworth Wassell (Houston, Texas); Daniel E. Burgess (Portland, Connecticut); Jason R. Barbely (East Islip, New York); Fred Lamar Thompson (Somers, Connecticut) |
ABSTRACT | A system for damping vibration in a drill string can include a magnetorheological fluid valve assembly having a supply of a magnetorheological fluid. A remanent magnetic field is induced in the valve during operation that can be used to provide the magnetic field for operating the valve so as to eliminate the need to energize the coils except temporarily when changing the amount of damping required. The current to be supplied to the coil for inducing a desired magnetic field in the valve is determined based on the limiting hysteresis curve of the valve and the history of the magnetization of the value using a binary search methodology. The history of the magnetization of the valve is expressed as a series of sets of current and it resulting magnetization at which the current experienced a reversal compared to prior values of the current. |
FILED | Thursday, September 08, 2011 |
APPL NO | 13/228376 |
ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 17/07 (20130101) Original (OR) Class E21B 17/073 (20130101) E21B 44/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976441 | Lacy et al. |
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FUNDED BY |
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APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Benjamin Paul Lacy (Greer, South Carolina); Gary Michael Itzel (Simpsonville, South Carolina); Srikanth Chandrudu Kottilingam (Simpsonville, South Carolina); Sandip Dutta (Greenville, South Carolina); David Edward Schick (Greenville, South Carolina) |
ABSTRACT | An article and method of forming an article are provided. The article includes a body portion separating an inner region and an outer region, an aperture in the body portion, the aperture fluidly connecting the inner region to the outer region, and a conduit extending from an outer surface of the body portion at the aperture and being arranged and disposed to controllably direct fluid from the inner region to the outer region. The method includes providing a body portion separating an inner region and an outer region, providing an aperture in the body portion, and forming a conduit over the aperture, the conduit extending from an outer surface of the body portion and being arranged and disposed to controllably direct fluid from the inner region to the outer region. The article is arranged and disposed for insertion within a hot gas path component. |
FILED | Friday, May 29, 2015 |
APPL NO | 14/725374 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/189 (20130101) F01D 9/02 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) F05D 2260/201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976487 | Hughes et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Michael John Hughes (Pittsburgh, Pennsylvania); Jonathan Dwight Berry (Simpsonville, South Carolina) |
ABSTRACT | A gas turbine that includes a working fluid flowpath extending aftward from a forward injector in a combustor. The combustor may include an inner radial wall, an outer radial wall, and, therebetween, a flow annulus. A staged injector may intersect the flow annulus so to attain an injection point within the working fluid flowpath by which aftward and forward annulus sections are defined. Air directing structure may include an aftward intake section that corresponds to the aftward annulus section and a forward intake section that corresponds to the forward annulus section. The air directing structure may be configured to: direct air entering through the aftward intake section through the aftward annulus section in a forward direction to the staged injector; and direct air entering through the forward intake section through the forward annulus section in an aftward direction to the staged injector. |
FILED | Tuesday, December 22, 2015 |
APPL NO | 14/977993 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) F02C 7/222 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 3/06 (20130101) F23R 3/346 (20130101) F23R 2900/03044 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976915 | DeSilva |
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FUNDED BY |
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APPLICANT(S) | Upul DeSilva (Oviedo, Florida) |
ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
INVENTOR(S) | Upul DeSilva (Oviedo, Florida) |
ABSTRACT | A method and system for determining a temperature of a working gas passing through a passage to a turbine section of a gas turbine engine. The method includes identifying an acoustic frequency at a first location in the engine upstream from the turbine section, and using the acoustic frequency for determining a first temperature value at the first location that is directly proportional to the acoustic frequency and a calculated constant value. A second temperature of the working gas is determined at a second location in the engine and, using the second temperature, a back calculation is performed to determine a temperature value for the working gas at the first location. The first temperature value is compared to the back calculated temperature value to change the calculated constant value to a recalculated constant value. Subsequent first temperature values at the first location may be determined based on the recalculated constant value. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/804132 |
ART UNIT | 2865 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/26 (20130101) G01K 13/02 (20130101) Original (OR) Class G01K 15/005 (20130101) G01K 2013/024 (20130101) G01K 2213/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977609 | Jayasena et al. |
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FUNDED BY |
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APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
INVENTOR(S) | Nuwan S. Jayasena (Sunnyvale, California); Dong Ping Zhang (San Jose, California); Paula Aguilera Diez (San Jose, California) |
ABSTRACT | Systems, apparatuses, and methods for implementing efficient queues and other data structures. A queue may be shared among multiple processors and/or threads without using explicit software atomic instructions to coordinate access to the queue. System software may allocate an atomic queue and corresponding queue metadata in system memory and return, to the requesting thread, a handle referencing the queue metadata. Any number of threads may utilize the handle for accessing the atomic queue. The logic for ensuring the atomicity of accesses to the atomic queue may reside in a management unit in the memory controller coupled to the memory where the atomic queue is allocated. |
FILED | Monday, March 07, 2016 |
APPL NO | 15/063186 |
ART UNIT | 2139 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 3/0613 (20130101) Original (OR) Class G06F 3/0658 (20130101) G06F 3/0673 (20130101) G06F 12/10 (20130101) G06F 12/023 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978469 | Vencelj et al. |
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FUNDED BY |
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APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee); Jozef Stefan Institute (Ljubljana, Slovenia); AISense d.o.o (Podsreda, Slovenia) |
INVENTOR(S) | Matjaz Vencelj (Ljubljana, Slovenia); Ashley C. Stowe (Knoxville, Tennessee); Toni Petrovic (Ljubljana, Slovenia); Jonathan S. Morrell (Farragut, Tennessee); Andrej Kosicek (Podsreda, Slovenia) |
ABSTRACT | A radiation area monitor device/method, utilizing: a radiation sensor having a directional radiation sensing capability; a rotation mechanism operable for selectively rotating the radiation sensor such that the directional radiation sensing capability selectively sweeps an area of interest; and a processor operable for analyzing and storing a radiation fingerprint acquired by the radiation sensor as the directional radiation sensing capability selectively sweeps the area of interest. Optionally, the radiation sensor includes a gamma and/or neutron radiation sensor. The device/method selectively operates in: a first supervised mode during which a baseline radiation fingerprint is acquired by the radiation sensor; and a second unsupervised mode during which a subsequent radiation fingerprint is acquired by the radiation sensor, wherein the subsequent radiation fingerprint is compared to the baseline radiation fingerprint and, if a predetermined difference threshold is exceeded, an alert is issued. |
FILED | Wednesday, December 20, 2017 |
APPL NO | 15/848832 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/16 (20130101) G01T 3/00 (20130101) G01T 7/125 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 3/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978470 | Gelis et al. |
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FUNDED BY |
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APPLICANT(S) | Artem V. Gelis (Naperville, Illinois); Andrew J. Castiglioni (Chicago, Illinois); Dennis Kelley (Indianapolis, Indiana); Anatoliy Galkin (Almaty, Kazakhstan); Nadezhda Bachilova (Almaty, Kazakhstan); Alexandr Klepikov (Almaty, Kazakhstan); Alexandr Blynskiy (Almaty, Kazakhstan); Turgynbek Tolebayev (Almaty, Kazakhstan) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Artem V. Gelis (Naperville, Illinois); Andrew J. Castiglioni (Chicago, Illinois); Dennis Kelley (Indianapolis, Indiana); Anatoliy Galkin (Almaty, Kazakhstan); Nadezhda Bachilova (Almaty, Kazakhstan); Alexandr Klepikov (Almaty, Kazakhstan); Alexandr Blynskiy (Almaty, Kazakhstan); Turgynbek Tolebayev (Almaty, Kazakhstan) |
ABSTRACT | A method for immobilizing liquid radioactive waste is provided, the method having the steps of mixing waste with polymer to form a non-liquid waste; contacting the non-liquid waste with a solidifying agent to create a mixture, heating the mixture to cause the polymer, waste, and filler to irreversibly bind in a solid phase, and compressing the solid phase into a monolith. The invention also provides a method for immobilizing liquid radioactive waste containing tritium, the method having the steps of mixing liquid waste with polymer to convert the liquid waste to a non-liquid waste, contacting the non-liquid waste with a solidifying agent to create a mixture, heating the mixture to form homogeneous, chemically stable solid phase, and compressing the chemically stable solid phase into a final waste form, wherein the polymer comprises approximately a 9:1 weight ratio mixture of styrene block co-polymers and cross linked co-polymers of acrylamides. |
FILED | Monday, December 14, 2015 |
APPL NO | 14/967935 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/162 (20130101) G21F 9/165 (20130101) G21F 9/167 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978474 | Yaghi et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Omar M. Yaghi (Berkeley, California); Shun Wan (Santa Monica, California); Christian J. Doonan (Eastwood, Australia); Bo Wang (Beijing, China PRC); Hexiang Deng (Albany, California) |
ABSTRACT | The disclosure relates generally to materials that comprise conductive covalent organic frameworks. The disclosure also relates to materials that are useful to store and separate gas molecules and sensors. |
FILED | Monday, February 22, 2016 |
APPL NO | 15/050136 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) B01J 20/26 (20130101) Heterocyclic Compounds C07D 487/22 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/324 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978895 | Anderson et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Benjamin John Anderson (Albuquerque, New Mexico); Gregory N. Nielson (Albuquerque, New Mexico); Jose Luis Cruz-Campa (Albuquerque, New Mexico); Murat Okandan (Edgewood, New Mexico); Anthony L. Lentine (Albuquerque, New Mexico); Paul J. Resnick (Albuquerque, New Mexico) |
ABSTRACT | An apparatus, method, and system, the apparatus and system including a flexible microsystems enabled microelectronic device package including a microelectronic device positioned on a substrate; an encapsulation layer encapsulating the microelectronic device and the substrate; a protective layer positioned around the encapsulating layer; and a reinforcing layer coupled to the protective layer, wherein the substrate, encapsulation layer, protective layer and reinforcing layer form a flexible and optically transparent package around the microelectronic device. The method including encapsulating a microelectronic device positioned on a substrate within an encapsulation layer; sealing the encapsulated microelectronic device within a protective layer; and coupling the protective layer to a reinforcing layer, wherein the substrate, encapsulation layer, protective layer and reinforcing layer form a flexible and optically transparent package around the microelectronic device. |
FILED | Thursday, October 31, 2013 |
APPL NO | 14/068189 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/048 (20130101) Original (OR) Class H01L 31/049 (20141201) H01L 31/1892 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978968 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Industry-Academic Cooperation Foundation, Dankook University (Gyeongii-do, South Korea) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Industry-Academic Cooperation Foundation, Dankook University (Gyeonggi-Do, South Korea) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Jun Yeob Lee (Gyeonggi-do, South Korea); Yong Joo Cho (Seoul, South Korea) |
ABSTRACT | Disclosed herein are processes for fabricating organic photosensitive optoelectronic devices with a vertical compositionally graded organic active layer. The processes use either a single-stamp or double-stamp printing technique to transfer the vertical compositionally graded organic active layer from a starting substrate to a device layer. |
FILED | Monday, October 27, 2014 |
APPL NO | 15/030136 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/003 (20130101) H01L 51/0004 (20130101) H01L 51/0034 (20130101) H01L 51/0036 (20130101) H01L 51/0047 (20130101) H01L 51/0094 (20130101) H01L 51/424 (20130101) Original (OR) Class H01L 51/4253 (20130101) H01L 2251/303 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979026 | Chung et al. |
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FUNDED BY |
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APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Hoon Taek Chung (Los Alamos, New Mexico); Piotr Zelenay (Los Alamos, New Mexico) |
ABSTRACT | A catalyst for oxygen reduction reaction (ORR) for a fuel cell was prepared by pyrolyzing a mixture of polyaniline, cyanamide, carbon black, and a non-precious metal salt under an inert atmosphere. The pyrolyzed product was treated to remove acid soluble components and then pyrolyzed again. The resulting powder was used to prepare a cathode for a membrane electrode assembly that was used in a fuel cell. When iron(III) chloride was used as the salt, the resulting catalyst was porous with a web-shaped structure. It displayed a maximum power density of 0.79 W/cm at 0.4 V in H2/O2 at 1.0 bar back pressure. |
FILED | Monday, September 30, 2013 |
APPL NO | 14/042249 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/881 (20130101) H01M 4/8668 (20130101) H01M 4/8807 (20130101) H01M 4/8828 (20130101) H01M 4/9008 (20130101) Original (OR) Class H01M 8/1004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979039 | Gorte et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Raymond J. Gorte (Narberth, Pennsylvania); Tae-Sik Oh (Wynnewood, Pennsylvania) |
ABSTRACT | Disclosed are novel configurations of Direct Carbon Fuel Cells (DCFCs), which optionally comprise a liquid anode. The liquid anode comprises a molten salt/metal, preferably Sb, and a fuel, which has significant elemental carbon content (coal, bio-mass, etc.). The supply of fuel is continuously replenished in the anode. In addition, a stack configuration is suggested where combining a large number of planar or tubular fuel elements. |
FILED | Monday, March 17, 2014 |
APPL NO | 14/785133 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8621 (20130101) H01M 8/124 (20130101) H01M 8/0656 (20130101) H01M 8/1213 (20130101) H01M 8/1233 (20130101) Original (OR) Class H01M 8/1246 (20130101) H01M 2008/1293 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979060 | Zhamu et al. |
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FUNDED BY |
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APPLICANT(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
INVENTOR(S) | Aruna Zhamu (Springboro, Ohio); Bor Z. Jang (Centerville, Ohio) |
ABSTRACT | A flexible, asymmetric electrochemical cell comprising: (A) A sheet of graphene paper as first electrode comprising nano graphene platelets having a platelet thickness less than 1 nm, wherein the first electrode has electrolyte-accessible pores; (B) A thin-film or paper-like first separator and electrolyte; and (C) A thin-film or paper-like second electrode which is different in composition than the first electrode; wherein the separator is sandwiched between the first and second electrode to form a flexible laminate configuration. The asymmetric supercapacitor cells with different NGP-based electrodes exhibit an exceptionally high capacitance, specific energy, and stable and long cycle life. |
FILED | Monday, March 20, 2017 |
APPL NO | 15/463531 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/26 (20130101) H01G 11/36 (20130101) H01G 11/52 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022425 (20130101) H01L 51/0048 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/587 (20130101) H01M 12/005 (20130101) H01M 16/003 (20130101) Original (OR) Class H01M 2300/0045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979320 | Singh et al. |
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FUNDED BY |
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APPLICANT(S) | Deere and Company (Moline, Illinois) |
ASSIGNEE(S) | DEERE and COMPANY (Moline, Illinois) |
INVENTOR(S) | Brij N. Singh (West Fargo, North Dakota); Christopher J. Schmit (Fargo, North Dakota) |
ABSTRACT | A first driver portion comprises a set of first components mounted on or associated with a first circuit board. A second circuit board is spaced apart from the first circuit board. A second driver portion comprises a set of second components mounted on or associated with the second circuit board, where the first driver portion and the second driver portion collectively are adapted to provide input signals to the control terminal of each semiconductor switch of an inverter. A first edge connector is mounted on the first circuit board. A second edge connector is mounted on the second circuit board. An interface board has mating edges that mate with the first edge connector and the second edge connector. |
FILED | Friday, August 26, 2016 |
APPL NO | 15/248241 |
ART UNIT | 2838 — Electrical Circuits and Systems |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 15/18 (20130101) G01R 15/202 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/072 (20130101) H01L 29/1608 (20130101) H01L 29/2003 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 7/003 (20130101) H02M 7/537 (20130101) Original (OR) Class H02M 2001/0009 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 27/06 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/117 (20130101) H05K 1/144 (20130101) H05K 1/165 (20130101) H05K 1/181 (20130101) H05K 2201/042 (20130101) H05K 2201/10151 (20130101) H05K 2201/10166 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979668 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Gregory K. Chen (Portland, Oregon); Mark A. Anders (Hillsboro, Oregon); Himanshu Kaul (Portland, Oregon); Ram K. Krishnamurthy (Portland, Oregon); Aaron T. Stillmaker (West Sacramento, California) |
ABSTRACT | A first packet-switched reservation request is received. Data associated with the first packet-switched reservation request is communicated through a first circuit-switched channel according to a best effort communication scheme. A second packet-switched reservation request is received. Data associated with the second packet-switched reservation request is communicated through a second circuit-switched channel according to a guaranteed throughput communication scheme. |
FILED | Monday, December 22, 2014 |
APPL NO | 14/579303 |
ART UNIT | 2464 — Multiplex and VoIP |
CURRENT CPC | Electric Digital Data Processing G06F 15/7825 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 47/72 (20130101) H04L 47/625 (20130101) Original (OR) Class H04L 49/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980415 | Zhou et al. |
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FUNDED BY |
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APPLICANT(S) | Toyota Motor Engineering and Manufacturing North America, Inc. (Erlanger, Kentucky) |
ASSIGNEE(S) | Toyota Motor Engineering and Manufacturing North America, Inc. (Erlanger, Kentucky) |
INVENTOR(S) | Feng Zhou (South Lyon, Michigan); Ercan Mehmet Dede (Ann Arbor, Michigan) |
ABSTRACT | A modular jet impingement assembly includes an inlet tube fluidly coupled to a fluid inlet, an outlet tube fluidly coupled to a fluid outlet, and a modular manifold having a first distribution recess extending into a first side of the modular manifold, a second distribution recess extending into a second side of the modular manifold, a plurality of inlet connection tubes positioned at an inlet end of the modular manifold, and a plurality of outlet connection tubes positioned at an outlet end of the modular manifold. A first manifold insert is removably positioned within the first distribution recess, a second manifold insert is removably positioned within the second distribution recess, and a first and second heat transfer plate each removably coupled to the modular manifold. The first and second heat transfer plates each comprise an impingement surface. |
FILED | Thursday, August 20, 2015 |
APPL NO | 14/831208 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20927 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 09974474 | Principe et al. |
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FUNDED BY |
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APPLICANT(S) | Jose C. Principe (Gainesville, Florida); Dorothee Maroserro (Paris, France); Tammy Y. Euliano (Gainesville, Florida); Neil Russell Euliano, II (Gainesville, Florida) |
ASSIGNEE(S) | Convergent Engineering, Inc. (Gainesville, Florida); University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Jose C. Principe (Gainesville, Florida); Dorothee Maroserro (Paris, France); Tammy Y. Euliano (Gainesville, Florida); Neil Russell Euliano, II (Gainesville, Florida) |
ABSTRACT | Systems and methods for monitoring uterus contraction activity and progress of labor. The system of the subject invention can comprises (1) a plurality of sensors; (2) an amplifying/filtering means; (3) a computing means; and (4) a graphical user interface. Accurate clinical data, which can be extracted and provided to the user in real-time using the system of the invention, include without limitation, progress of labor, prediction and monitoring of preterm labor, and intrauterine pressure prediction. In a preferred embodiment, the system of the invention includes an intelligence means, such as a neural network system, to analyze and interpret clinical data for use in clinical diagnosis as well as delivery strategy. |
FILED | Tuesday, April 10, 2012 |
APPL NO | 13/443161 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1107 (20130101) A61B 5/4356 (20130101) Original (OR) Class A61B 5/04882 (20130101) A61B 5/7264 (20130101) A61B 2503/02 (20130101) A61B 2562/046 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974932 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Brian J. Kim (Los Angeles, California); Ellis Meng (La Canada Flintridge, California) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Brian J. Kim (Los Angeles, California); Ellis Meng (La Canada Flintridge, California) |
ABSTRACT | A self-monitoring catheter system may detect an obstruction during use of a catheter. The system may include a catheter with an interior lumen that has one or more ports into the lumen; a first and a second electrode; and an impedance measurement instrument that measures changes in the impedance between the first and the second electrodes after the first electrode is exposed to fluid within the catheter lumen, thereby signaling an obstruction during use of the catheter. |
FILED | Monday, August 10, 2015 |
APPL NO | 14/822662 |
ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0538 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 27/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974962 | Talkachova |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Alena Talkachova (Shoreview, Minnesota) |
ABSTRACT | In a method of preventing the formation of alternans in the heart of a patient, the heart is paced to control the TR interval of each heartbeat. The method may be performed using a heart monitoring and pacing device that includes a processor, memory, an electrocardiogram (ECG) sensing circuit, and a pulse generator. In the method, a heartbeat rate of the heart is detected and comparted to a threshold value stored in the memory. The heart is paced using the pulse generator to force the TR period of a limited number of heartbeats toward a targeted TR period, which is stored in the memory. |
FILED | Friday, April 24, 2015 |
APPL NO | 14/695593 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0245 (20130101) A61B 5/0452 (20130101) A61B 5/02405 (20130101) A61B 5/04012 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/025 (20130101) A61N 1/3627 (20130101) Original (OR) Class A61N 1/36507 (20130101) A61N 1/36514 (20130101) A61N 1/36592 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975038 | Bucci et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Liam David Bucci (Irvine, California); Ting-Shuo Chou (Irvine, California); Jeffrey Lawrence Krichmar (Cardiff By The Sea, California) |
ABSTRACT | In one embodiment, a neuromorphic robot includes a curved outer housing, and multiple touch sensors provided on the outer housing, wherein the robot is configured to interpret a touch of a user sensed with the touch sensors. |
FILED | Tuesday, November 04, 2014 |
APPL NO | 14/532353 |
ART UNIT | 3717 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 9/24 (20130101) Original (OR) Class A63F 9/0604 (20130101) A63F 2009/2408 (20130101) A63F 2009/2447 (20130101) Toys, e.g Tops, Dolls, Hoops or Building Blocks A63H 33/005 (20130101) A63H 2200/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40625 (20130101) G05B 2219/40627 (20130101) Computer Systems Based on Specific Computational Models G06N 3/008 (20130101) G06N 3/049 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) Y10S 901/46 (20130101) Y10S 901/47 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975084 | Merkel et al. |
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FUNDED BY |
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APPLICANT(S) | Membrane Technology and Research, Inc. (Newark, California); New York University (New York, New York) |
ASSIGNEE(S) | Membrane Technology and Research, Inc. (Newark, California); New York University (New York, New York) |
INVENTOR(S) | Timothy C Merkel (San Jose, California); Hao Zhang (Fremont, California); Zhenjie He (Fremont, California); Johannes G Wijmans (Menlo Park, California); Yoshiyuki Okamoto (Brooklyn, New York) |
ABSTRACT | A process for separating components or a fluid mixture using membranes comprising a selective layer made from copolymers of an amorphous per fluorinated dioxolane and a fluorovinyl monomer. The resulting membranes have superior selectivity performance for certain fluid components of interest while maintaining fast permeance compared to membranes prepared using conventional perfluoropolymers, such as Teflon® AF, Hyflon® AD, and Cytop®. |
FILED | Tuesday, May 30, 2017 |
APPL NO | 15/608399 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 53/28 (20130101) B01D 53/228 (20130101) Original (OR) Class B01D 61/36 (20130101) B01D 61/362 (20130101) B01D 71/32 (20130101) B01D 71/38 (20130101) B01D 2256/24 (20130101) B01D 2256/245 (20130101) B01D 2257/11 (20130101) B01D 2257/102 (20130101) B01D 2257/108 (20130101) B01D 2257/502 (20130101) B01D 2257/504 (20130101) B01D 2257/7025 (20130101) B01D 2325/04 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/503 (20130101) C01B 21/0444 (20130101) C01B 23/0047 (20130101) C01B 2203/048 (20130101) C01B 2203/0405 (20130101) C01B 2210/007 (20130101) C01B 2210/0012 (20130101) C01B 2210/0031 (20130101) Acyclic or Carbocyclic Compounds C07C 7/144 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/104 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/152 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09975196 — Measurement of three-dimensional welding torch orientation for manual arc welding process
US 09975196 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Illinois Tool Works Inc. (Glenview, Illinois) |
ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
INVENTOR(S) | Yuming Zhang (Nicholasville, Kentucky); WeiJie Zhang (Windsor, Canada) |
ABSTRACT | Methods and systems are provided herein for measuring 3D apparatus (e.g., manual tool or tool accessory) orientation. Example implementations use an auto-nulling algorithm that incorporates a quaternion-based unscented Kalman filter. Example implementations use a miniature inertial measurement unit endowed with a tri-axis gyro and a tri-axis accelerometer. The auto-nulling algorithm serves as an in-line calibration procedure to compensate for the gyro drift, which has been verified to significantly improve the estimation accuracy in three-dimensions, especially in the heading estimation. |
FILED | Friday, October 30, 2015 |
APPL NO | 14/928496 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/0953 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/16 (20130101) G01C 25/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 21/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975817 | Temme et al. |
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FUNDED BY |
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APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
ASSIGNEE(S) | Pivot Bio, Inc. (Berkeley, California) |
INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Oakland, California); Rosemary Clark (Emeryville, California); Emily Tung (Millbrae, California) |
ABSTRACT | Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria's nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant. |
FILED | Wednesday, June 28, 2017 |
APPL NO | 15/636595 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Nitrogenous Fertilisers C05C 1/00 (20130101) C05C 1/00 (20130101) C05C 3/005 (20130101) C05C 3/005 (20130101) C05C 5/005 (20130101) C05C 5/005 (20130101) C05C 11/00 (20130101) C05C 11/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class C05F 11/08 (20130101) C05F 11/08 (20130101) C05F 11/08 (20130101) C05F 11/08 (20130101) Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975916 | Yin et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Peng Yin (Brookline, Massachusetts); Diming Wei (Cambridge, Massachusetts); Mingjie Dai (Boston, Massachusetts); Cameron Myhrvold (Cambridge, Massachusetts); Yonggang Ke (Atlanta, Georgia); Ralf Jungmann (Cambridge, Massachusetts) |
ABSTRACT | The invention provides SST motifs of controlled size and shape, comprised of a plurality of oligonucleotides, and methods for their synthesis. The motifs are formed, at least in part, by the self-assembly of single stranded oligonucleotides into curved, corrugated or twisted structures. The location of each oligonucleotide in the resultant motif is known. Accordingly, the motifs may be modified with specificity. |
FILED | Wednesday, November 06, 2013 |
APPL NO | 14/440907 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 21/04 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1031 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975922 | Agris et al. |
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FUNDED BY |
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APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
ASSIGNEE(S) | The Research Foundation For The State University of New York (Albany, New York); North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Paul F. Agris (Albany, New York); Carol Hall (Raleigh, North Carolina); Xingqing Xiao (Raleigh, North Carolina) |
ABSTRACT | Disclosed are peptides that exhibit good binding to the anticodon stem and loop of human lysine tRNA species, tRNALys3. The starting point was the 15-amino-acid sequence, RVTHHAFLGAHRTVG, found to bind selectively to hypermodified tRNALys3. The peptide backbone conformation was determined via atomistic simulation of the peptide-ASLLys3complex and then held fixed throughout the search. Analysis of the binding structure and the various contributions to the binding energy shows that: 1) two hydrophilic residues (asparagine (ASN) at site 11 and the cysteine (CYS) at site 12) “recognize” the ASLLys3 due to the VDW energy, and thereby contribute to its binding specificity, and 2) the positively-charged arginines (ARG) at sites 4 and 13 preferentially attract the negatively-charged sugar rings and the phosphate linkages, and thereby contribute to the binding affinity. |
FILED | Tuesday, October 21, 2014 |
APPL NO | 15/030739 |
ART UNIT | 1675 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976011 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Hao Li (Columbia, Missouri); Qingson Yu (Columbia, Missouri); Liang Chen (Columbia, Missouri); Meng Chen (Columbia, Missouri) |
ASSIGNEE(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
INVENTOR(S) | Hao Li (Columbia, Missouri); Qingson Yu (Columbia, Missouri); Liang Chen (Columbia, Missouri); Meng Chen (Columbia, Missouri) |
ABSTRACT | The present invention provides polymer composites reinforced with high aspect ratio reinforcing fillers selected from calcium phosphate nanofibers, nanoplates, submicron fibers, submicron plates, and combinations thereof. The mechanical and biological properties of the inventive composites are enhanced significantly over current polymer composites and may be employed in various biomedical applications, such as dental restorations. |
FILED | Thursday, July 14, 2011 |
APPL NO | 13/183221 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/08 (20130101) Original (OR) Class C08K 2201/011 (20130101) C08K 2201/016 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976120 | Blick et al. |
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FUNDED BY |
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APPLICANT(S) | Robert H. Blick (Madison, Wisconsin); Justin Williams (Cambridge, Wisconsin); Minrui Yu (Madison, Wisconsin); Yu Huang (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Robert H. Blick (Madison, Wisconsin); Justin Williams (Cambridge, Wisconsin); Minrui Yu (Madison, Wisconsin); Yu Huang (Madison, Wisconsin) |
ABSTRACT | A scaffold for neurons consists of tubes sized to promote neural growth through the tubes. The tubes may be fixed to a substrate providing electrical or optical paths out from the interior of the tubes from sensors or stimulating probes at one or more locations along the length of the coaxial axons. Steering electrodes at spaces between tubes may be used to selectively promote the growth of interconnections of different axons in a one, two, or three-dimensional fashion. |
FILED | Monday, September 13, 2010 |
APPL NO | 12/880776 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2535/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976939 | Hall et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Benjamin Hall (State College, Pennsylvania); Jonathan Lynch (Boalsburg, Pennsylvania); Edward W. Reutzel (State College, Pennsylvania); Galen Lynch (Cambridge, Massachusetts) |
ABSTRACT | A laser ablation tomography system includes a specimen stage for supporting a specimen. A specimen axis is defined such that a specimen disposed generally on the axis may be imaged. A laser system is operable to produce a laser sheet in a plane intersecting the specimen axis and generally perpendicular thereto. An imaging system is operable to image the area where the laser sheet intersects the specimen axis. |
FILED | Friday, July 29, 2016 |
APPL NO | 15/223382 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/06 (20130101) Original (OR) Class G01N 21/27 (20130101) G01N 2001/045 (20130101) G01N 2001/2886 (20130101) Image Data Processing or Generation, in General G06T 17/00 (20130101) G06T 2200/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976953 | Pagan et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Charlotte (Charlotte, North Carolina); AquiSense Technologies LLC (Walton, Kentucky) |
ASSIGNEE(S) | AquiSense Technologies LLC (Erlanger, Kentucky); The University of North Carolina at Charlotte (Charlotte, North Carolina) |
INVENTOR(S) | Jennifer Godwin Pagan (Charlotte, North Carolina); Edward Brittain Stokes (Charlotte, North Carolina); Paolo Batoni (Charlotte, North Carolina) |
ABSTRACT | The present disclosure relates generally to systems and methods for determining the absorption coefficient and the optical density of a fluid as they relate to the wavelength of incident radiation. Specifically, ultraviolet light-emitting diodes (UV LEDs) or the like that emit ultraviolet (UV) radiation or the like are used as sources for irradiating the interior of an integrating chamber that is designed to increase the path length of the radiation through the fluid, thus enhancing the detection limits of the absorption coefficient and the optical density according to Beer's Law. |
FILED | Wednesday, May 07, 2014 |
APPL NO | 14/271859 |
ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 9/205 (20130101) A61L 2209/11 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 2209/11 (20130101) C02F 2303/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/031 (20130101) G01N 21/33 (20130101) G01N 21/5907 (20130101) Original (OR) Class G01N 2201/065 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976974 | Nguyen et al. |
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FUNDED BY |
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APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Tram Nguyen (Salt Lake City, Utah); Jules John Magda (Salt Lake City, Utah); Seung-Hei Cho (Salt Lake City, Utah); Prashant Tathireddy (Salt Lake City, Utah) |
ABSTRACT | Osmolarity-responsive hydrogel sensors, particularly biosensors, containing quaternary ammonium functionality, which are useful for, inter alia, continuous osmolarity monitoring with no pH interference, are disclosed. Methods of using the osmolarity-responsive hydrogels are also disclosed. |
FILED | Tuesday, January 26, 2016 |
APPL NO | 15/006496 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 7/00 (20130101) G01N 13/04 (20130101) G01N 27/045 (20130101) Original (OR) Class G01N 33/48707 (20130101) G01N 33/48785 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/2404 (20130101) H01R 13/533 (20130101) H01R 43/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977026 | Kaplan et al. |
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FUNDED BY |
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APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
INVENTOR(S) | Daniel L. Kaplan (Tallahassee, Florida); Irina Bruck (Tallahassee, Florida) |
ABSTRACT | Identified herein is a novel post-translational modification of Mcm2, wherein the residue of serines 53 and 108 are phosphorylated. DDK phosphorylates Mcm2 at serines 53 and 108 when stimulated by Treslin. DDK is overexpressed in many human cancers, including colorectal cancer, suggesting that monitoring the phosphorylation of Mcm2 at serines 53 and 108 may detect early cancer with high sensitivity and specificity. It was also found that the homologous modification in budding yeast is required for DNA replication, and the modification occurs in cells during active DNA replication only. In an embodiment, the current invention is an antibody specific for human Mcm2 that is phosphorylated at serines 53 and 108. This antibody was found to be overexpressed in colon cancer cell line HCT 116, as well as other cancer cell lines, compared to normal cells. |
FILED | Wednesday, July 27, 2016 |
APPL NO | 15/221282 |
ART UNIT | 1678 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57419 (20130101) Original (OR) Class G01N 2333/47 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977028 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | Ohio University (Athens, Ohio) |
ASSIGNEE(S) | Ohio University (Athens, Ohio) |
INVENTOR(S) | Hao Chen (Athens, Ohio); Ning Pan (Jinan, China PRC); Pengyuan Liu (Dandong, China PRC) |
ABSTRACT | A mass spectrometry-based method for analyzing an acidic organic target compound includes directing a charged solvent (44) toward a pre-acidified sample (12) comprising the target compound, to thereby ionize the pre-acidified sample (12). The method further includes directing the ionized pre-acidified sample (54) to a mass spectrometer (18), the mass spectrometer (18) being configured to identify and quantify the target compound. |
FILED | Thursday, November 07, 2013 |
APPL NO | 14/441385 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) C12Q 1/6806 (20130101) C12Q 2565/627 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/66 (20130101) G01N 33/6842 (20130101) G01N 33/6848 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/165 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977859 | Nolte et al. |
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FUNDED BY |
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APPLICANT(S) | David D. Nolte (Lafayette, Indiana); Kwan Jeong (Seoul, South Korea) |
ASSIGNEE(S) | PURDUE RESERACH FOUNDATION (West Lafayette, Indiana) |
INVENTOR(S) | David D. Nolte (Lafayette, Indiana); Kwan Jeong (Seoul, South Korea) |
ABSTRACT | Motility contrast imaging (MCI) is a depth-resolved holographic technique to extract cellular and subcellular motion inside tissue. The holographic basis of the measurement technique makes it highly susceptible to mechanical motion. The motility contrast application, in particular, preferably includes increased mechanical stability because the signal is based on time-varying changes caused by cellular motion, not to be confused with mechanical motion of the system. The use of the resulting spectrogram response signatures, or “fingerprint” data, of known compounds is disclosed to screen new compounds for leads as to those having potentially beneficial mechanisms of action. The “fingerprint” data of known toxic compounds can be used to screen new compounds for toxicity. |
FILED | Friday, June 17, 2011 |
APPL NO | 13/704464 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/4845 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) Holographic Processes or Apparatus G03H 1/32 (20130101) G03H 1/0443 (20130101) G03H 1/0866 (20130101) G03H 2001/045 (20130101) G03H 2001/0445 (20130101) G03H 2001/0447 (20130101) G03H 2001/0467 (20130101) G03H 2222/24 (20130101) Electric Digital Data Processing G06F 19/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978288 | Lok et al. |
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FUNDED BY |
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APPLICANT(S) | Benjamin Chak Lum Lok (Gainesville, Florida); David Scott Lind (Martinez, Georgia); Juan Carlos Cendan (Gainesville, Florida); Andrew Brian Raij (Winter Park, Florida); Brent H. Rossen (Gainesville, Florida); Aaron Andrew Kotranza (Gainesville, Florida); Kyle John Johnsen (Athens, Georgia) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Augusta University Research Institute, Inc. (Augusta, Georgia) |
INVENTOR(S) | Benjamin Chak Lum Lok (Gainesville, Florida); David Scott Lind (Martinez, Georgia); Juan Carlos Cendan (Gainesville, Florida); Andrew Brian Raij (Winter Park, Florida); Brent H. Rossen (Gainesville, Florida); Aaron Andrew Kotranza (Gainesville, Florida); Kyle John Johnsen (Athens, Georgia) |
ABSTRACT | A system for providing interaction between a virtual human and a user, the system comprising: a tangible interface providing a physical interface between the user and the virtual human, an imaging system directed towards the physical interface to provide images of the user interacting with the tangible interface; a tracking system tracking at least one position or the user; a microphone capturing speech from the user; a simulation system receiving inputs from the tangible interface, the imaging system, the tracking system and the microphone, the simulation system generating output signals corresponding to the virtual human; and a display presenting the output signals to the user. |
FILED | Thursday, February 11, 2010 |
APPL NO | 13/148706 |
ART UNIT | 2625 — Selective Visual Display Systems |
CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 7/00 (20130101) Original (OR) Class G09B 23/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979240 | Parks et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Aaron N. Parks (Seattle, Washington); Joshua R. Smith (Seattle, Washington) |
ABSTRACT | Examples described herein include systems and methods for multiband harvesting. An example system may include a single wideband antenna followed by several narrowband rectifier chains. Each rectifier chain may include a bandpass filter, a tuned impedance matching network, and a rectifier. The outputs of the rectifiers may be combined using a summation network. The summation network, which may be a diode summation network, may in some examples provide good performance even when only a subset of the narrowband harvesters (e.g. a subset of the rectifier chains) is excited. |
FILED | Thursday, April 07, 2016 |
APPL NO | 15/093459 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/20 (20160201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979284 | Jung et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Wanyeong Jung (Ann Arbor, Michigan); Sechang Oh (Ann Arbor, Michigan); Suyoung Bang (Ann Arbor, Michigan); Yoonmyung Lee (Ann Arbor, Michigan); Dennis Sylvester (Ann Arbor, Michigan); David T. Blaauw (Ann Arbor, Michigan) |
ABSTRACT | A self-oscillating DC-DC converter structure is proposed in which an oscillator is completely internalized within the switched-capacitor network. This eliminates power overhead of clock generation and level shifting and enables higher efficiency at lower power levels. Voltage doublers are cascaded to form a complete energy harvester with a wide load range from 5 nW to 5 μW and self-starting operation down to 140 mV. Because each doubler is self-oscillating, the frequency of each stage can be independently modulated, thereby optimizing the overall conversion efficiency. |
FILED | Thursday, February 05, 2015 |
APPL NO | 15/116072 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/36 (20130101) H02M 3/07 (20130101) Original (OR) Class Pulse Technique H03K 3/0315 (20130101) H03K 19/017509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979323 | Ghule et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Aditya N. Ghule (Madison, Wisconsin); Baoyun Ge (Madison, Wisconsin); Daniel Colin Ludois (Madison, Wisconsin) |
ABSTRACT | A variable speed drive for an electrostatic motor provides feedback control by conversion of measured current phases provided to the motor into a vector in a rotating rotor framework. This vector is used for evaluating corrective voltages and then reconverted to a non-rotating framework for application to the motor electrodes. Current-source drive circuits provide current stabilized outputs making such sophisticated control tractable. |
FILED | Wednesday, November 22, 2017 |
APPL NO | 15/820829 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/008 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979463 | Shafer et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents for Northern Arizona Univ (Flagstaff, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents acting for and on behalf of Northern Arizona University (Flagstaff, Arizona) |
INVENTOR(S) | Michael W. Shafer (Flagstaff, Arizona); Paul G. Flikkema (Flagstaff, Arizona); Joseph Davidson (Flagstaff, Arizona) |
ABSTRACT | Implementations of UAV wildlife monitoring system may include a ground control station wirelessly coupled to a UAV which may include a flight controller, a first radio, a second radio, a first antenna, a second antenna, a very high frequency (VHF) radio receiver, and a computer, all operatively coupled together. The monitoring system may also include a VHF tag configured to be coupled to an animal, wherein when the VHF tag is coupled to the animal, the VHF radio receiver receives a VHF radio signal from the VHF tag using the first antenna, wherein the computer process the VHF radio signal to create the location data from the VHF radio signal, processes the location data, and sends the location data to the second radio, wherein the second radio transmits the location data into a telecommunications channel, and wherein the ground control station receives the location data from the telecommunications channel. |
FILED | Monday, April 17, 2017 |
APPL NO | 15/489604 |
ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/006 (20130101) A01K 29/005 (20130101) Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 31/002 (20130101) Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/12 (20130101) B64C 2201/146 (20130101) B64C 2201/203 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0252 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) G05D 1/0044 (20130101) Transmission H04B 1/10 (20130101) H04B 1/0343 (20130101) H04B 7/18504 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980388 | Tai et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Yu-Chong Tai (Pasadena, California); Han-Chieh Chang (Pasadena, California) |
ABSTRACT | A biocompatible, micro-fabricated ribbon cable is described in which at least one set of conductors diverges laterally into a bypass wing that forms an aperture through the ribbon cable. The bypass wing is folded in a line through the aperture and over a central portion of the ribbon cable, resulting in a ribbon cable with a narrow, stacked region. The narrow region can fit through small incisions in membranes, such as through an incision in a sclera of an eyeball. The ribbon cable can have an integrally-formed electrode array for attaching to a retina of an eyeball and other electronics for sending signals to the electrode array. |
FILED | Friday, December 18, 2015 |
APPL NO | 14/974242 |
ART UNIT | 3766 — Optics |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/36046 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/189 (20130101) Original (OR) Class H05K 3/064 (20130101) H05K 2201/052 (20130101) H05K 2201/0154 (20130101) H05K 2201/1003 (20130101) H05K 2201/10151 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 09975765 | Okojie |
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FUNDED BY |
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APPLICANT(S) | The United States of Americas as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Robert S. Okojie (Strongsville, Ohio) |
ABSTRACT | A process for fabricating relatively thin SiC diaphragms may include fast Reactive Ion Etching (RIE) followed by Dopant Selective Reactive Ion Etching (DSRIE). The process may produce silicon carbide (SiC) diaphragms thinner than 10 microns. These thinner, more sensitive diaphragms may then be used to effectively resolve sub-psi pressures in jet engines, for example. |
FILED | Friday, December 16, 2016 |
APPL NO | 15/381736 |
ART UNIT | 2891 — Semiconductors/Memory |
CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00595 (20130101) Original (OR) Class B81C 2201/0132 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/0042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976912 | Wallace |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | James Kent Wallace (Pasadena, California) |
ABSTRACT | Hybrid sensors comprising Shack-Hartmann Wavefront Sensor (S-HWFS) and Zernike Wavefront Sensor (Z-WFS) capabilities are presented. The hybrid sensor includes a Z-WFS optically arranged in-line with a S-HWFS such that the combined wavefront sensor operates across a wide dynamic range and noise conditions. The Z-WFS may include the ability to introduce a dynamic phase shift in both transmissive and reflective modes. |
FILED | Tuesday, April 14, 2015 |
APPL NO | 14/686616 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/00 (20130101) G01J 9/02 (20130101) G01J 9/0215 (20130101) Original (OR) Class G01J 2009/0226 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977121 | Fink et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Patrick W. Fink (Missouri City, Texas); Gregory Y. Lin (Friendswood, Texas); Timothy F. Kennedy (Sugar Land, Texas); Phong H. Ngo (Friendswood, Texas) |
ABSTRACT | A radio frequency identification (RFID) system includes an RFID interrogator and an RFID tag having a plurality of information sources and a beamforming network. The tag receives electromagnetic radiation from the interrogator. The beamforming network directs the received electromagnetic radiation to a subset of the plurality of information sources. The RFID tag transmits a response to the received electromagnetic radiation, based on the subset of the plurality of information sources to which the received electromagnetic radiation was directed. Method and other embodiments are also disclosed. |
FILED | Friday, June 23, 2017 |
APPL NO | 15/631862 |
ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/765 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/0008 (20130101) G06K 7/10366 (20130101) Antennas, i.e Radio Aerials H01Q 1/2208 (20130101) H01Q 3/40 (20130101) Transmission H04B 7/0408 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977848 | Wang |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Ten-See Wang (Huntsville, Alabama) |
ABSTRACT | Computational fluid dynamics (CFD) computations are performed at time increments using structural properties of the nozzle and flow properties of combustion products flowing through the nozzle. Each CFD computation accounts for movement of the wall geometry of the rocket nozzle due to the flowfield. Structural dynamics computations are performed at each time increment using the CFD computations in order to describe the movement of the wall geometry. Mesh dynamics computations at each time increment redefine the flowfield to account for the movement of the wall geometry. The mesh dynamics computations are based on a spring analogy process. The computations are iterated to solution convergence at each time increment with results being output to an output device. |
FILED | Tuesday, November 25, 2014 |
APPL NO | 14/553234 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 17/10 (20130101) G06F 17/5009 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977978 | Coulter et al. |
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FUNDED BY |
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APPLICANT(S) | San Diego State University Research Foundation (San Diego, California) |
ASSIGNEE(S) | San Diego State University Research Foundation (San Diego, California) |
INVENTOR(S) | Lloyd Lawrence Arthur Coulter (Escondido, California); Douglas A. Stow (San Diego, California) |
ABSTRACT | A method for collecting and processing remotely sensed imagery in order to achieve precise spatial co-registration (e.g., matched alignment) between multi-temporal image sets is presented. Such precise alignment or spatial co-registration of imagery can be used for change detection, image fusion, and temporal analysis/modeling. Further, images collected in this manner may be further processed in such a way that image frames or line arrays from corresponding photo stations are matched, co-aligned and if desired merged into a single image and/or subjected to the same processing sequence. A second methodology for automated detection of moving objects within a scene using a time series of remotely sensed imagery is also presented. Specialized image collection and preprocessing procedures are utilized to obtain precise spatial co-registration (image registration) between multitemporal image frame sets. In addition, specialized change detection techniques are employed in order to automate the detection of moving objects. |
FILED | Wednesday, November 14, 2012 |
APPL NO | 13/676854 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/3216 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 3/0093 (20130101) G06T 7/33 (20170101) G06T 7/254 (20170101) G06T 2207/10032 (20130101) G06T 2207/30181 (20130101) G06T 2207/30212 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09978686 | Spry et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | David J. Spry (Medina, Ohio); Philip G. Neudeck (Olmsted Township, Ohio) |
ABSTRACT | A process of fabrication and the resulting integrated circuit device is made of patterned metal electrical interconnections between semiconductor devices residing on and forming extremely harsh environment integrated circuit chips. The process enables more complicated wide band gap semiconductor integrated circuits with more than one level of interconnect to function for prolonged time periods (over 1000 hours) at much higher temperatures (500 C). |
FILED | Tuesday, February 21, 2017 |
APPL NO | 15/438130 |
ART UNIT | 2896 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/7685 (20130101) H01L 21/31116 (20130101) H01L 21/76802 (20130101) H01L 21/76879 (20130101) H01L 23/5226 (20130101) H01L 23/53266 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979322 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | Di Zhang (Niskayuna, New York); Rui Zhou (Niskayuna, New York); Luis Garces (Niskayuna, New York); Jiangbiao He (Schenectady, New York) |
ABSTRACT | The present disclosure is directed to a system and method for modulating a voltage output of a hybrid converter system having first and second set of Si-based power electronic devices coupled to first and second voltage source, respectively, and a first set of SiC-based power electronic devices coupled to the first and second sets of Si-based power electronic devices. The method includes switching between operational states of the hybrid converter system based on a desired voltage output, wherein each operational state includes one of the Si-based power electronic devices from the first and second sets of Si-based power electronic devices and one of the SiC-based devices from the first set of SiC-based power electronic devices being switched on and the remaining power electronic devices being switched off. Each SiC-based power electronic device of the first set of SiC-based power electronic devices switches at a higher frequency as compared to each Si-based power electronic device of the first and second sets of the Si-based power electronic devices. |
FILED | Friday, June 24, 2016 |
APPL NO | 15/192023 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/487 (20130101) H02M 7/5395 (20130101) Original (OR) Class H02M 2001/0048 (20130101) H02M 2001/0054 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 09974745 | Mannino et al. |
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FUNDED BY |
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APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
INVENTOR(S) | Raphael J. Mannino (Glen Gardner, New Jersey); Susan Gould-Fogerite (Annandale, New Jersey); Sara L. Krause-Elsmore (Kearny, New Jersey); David Delmarre (Jersey City, New Jersey); Ruying Lu (New Providence, New Jersey) |
ABSTRACT | Disclosed are novel methods for making cochleates and cochleate compositions that include introducing a cargo moiety to a liposome in the presence of a solvent. Also disclosed are cochleates and cochleate compositions that include an aggregation inhibitor, and optionally, a cargo moiety. Additionally, anhydrous cochleates that include a protonized cargo moiety, a divalent metal cation and a negatively charge lipid are disclosed. Methods of using the cochleate compositions of the invention, including methods of administration, are also disclosed. |
FILED | Thursday, January 30, 2014 |
APPL NO | 14/168752 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1274 (20130101) A61K 9/1277 (20130101) Original (OR) Class A61K 31/00 (20130101) A61K 31/60 (20130101) A61K 31/135 (20130101) A61K 31/167 (20130101) A61K 31/395 (20130101) A61K 31/7036 (20130101) A61K 31/7048 (20130101) A61K 38/12 (20130101) A61K 38/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09974853 | McCoy et al. |
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FUNDED BY |
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APPLICANT(S) | 13 Therapeutics, Inc. (Portland, Oregon) |
ASSIGNEE(S) | 13THERAPEUTICS, INC. (Portland, Oregon) |
INVENTOR(S) | Sharon L. McCoy (Portland, Oregon); Steven H. Hefeneider (Portland, Oregon) |
ABSTRACT | Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-α secretion through interaction with toll-like receptors. Experiments are described illustrating the efficacy of the compounds in treating otitis media. |
FILED | Tuesday, October 06, 2015 |
APPL NO | 14/876298 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/285 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/005 (20130101) C07K 14/07 (20130101) C07K 14/47 (20130101) C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09975817 | Temme et al. |
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FUNDED BY |
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APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
ASSIGNEE(S) | Pivot Bio, Inc. (Berkeley, California) |
INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Oakland, California); Rosemary Clark (Emeryville, California); Emily Tung (Millbrae, California) |
ABSTRACT | Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria's nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant. |
FILED | Wednesday, June 28, 2017 |
APPL NO | 15/636595 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Nitrogenous Fertilisers C05C 1/00 (20130101) C05C 1/00 (20130101) C05C 3/005 (20130101) C05C 3/005 (20130101) C05C 5/005 (20130101) C05C 5/005 (20130101) C05C 11/00 (20130101) C05C 11/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class C05F 11/08 (20130101) C05F 11/08 (20130101) C05F 11/08 (20130101) C05F 11/08 (20130101) Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976166 | Schellenberger et al. |
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FUNDED BY |
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APPLICANT(S) | Amunix Operating Inc. (Mountain View, California) |
ASSIGNEE(S) | AMUNIX OPERATING INC. (Mountain View, California) |
INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Chia-wei Wang (Santa Clara, California); Benjamin Spink (San Carlos, California); Willem P. C. Stemmer (Los Gatos, California); Nathan C. Geething (Santa Clara, California) |
ABSTRACT | The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions. |
FILED | Monday, December 21, 2015 |
APPL NO | 14/977035 |
ART UNIT | 1675 — Plants |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/7155 (20130101) C07K 14/8125 (20130101) C07K 14/70521 (20130101) C07K 16/18 (20130101) C07K 16/32 (20130101) C07K 16/40 (20130101) C07K 16/241 (20130101) C07K 16/244 (20130101) C07K 16/2809 (20130101) C07K 16/2863 (20130101) C07K 16/2878 (20130101) C07K 2317/31 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/31 (20130101) C07K 2319/70 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/625 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09979060 | Zhamu et al. |
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FUNDED BY |
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APPLICANT(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
INVENTOR(S) | Aruna Zhamu (Springboro, Ohio); Bor Z. Jang (Centerville, Ohio) |
ABSTRACT | A flexible, asymmetric electrochemical cell comprising: (A) A sheet of graphene paper as first electrode comprising nano graphene platelets having a platelet thickness less than 1 nm, wherein the first electrode has electrolyte-accessible pores; (B) A thin-film or paper-like first separator and electrolyte; and (C) A thin-film or paper-like second electrode which is different in composition than the first electrode; wherein the separator is sandwiched between the first and second electrode to form a flexible laminate configuration. The asymmetric supercapacitor cells with different NGP-based electrodes exhibit an exceptionally high capacitance, specific energy, and stable and long cycle life. |
FILED | Monday, March 20, 2017 |
APPL NO | 15/463531 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/26 (20130101) H01G 11/36 (20130101) H01G 11/52 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022425 (20130101) H01L 51/0048 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/587 (20130101) H01M 12/005 (20130101) H01M 16/003 (20130101) Original (OR) Class H01M 2300/0045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 09976182 | Khatib |
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FUNDED BY |
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APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Hasan Khatib (Fitchburg, Wisconsin) |
ABSTRACT | Single nucleotide polymorphic sites at positions 19069 and 25402 of the bovine STAT3 gene are associated with improved fertilization rate and/or improved embryo survival rate. The interactions between these two polymorphisms, and between them and the bovine STAT1 gene and fertilization and early embryonic survival rates were also disclosed. The interactions between STAT3 SNPs, and between STAT1 and STAT3 SNP19069 were highly significant for embryonic survival rate. Also disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods. |
FILED | Thursday, June 11, 2015 |
APPL NO | 14/736298 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6881 (20130101) Original (OR) Class C12Q 2600/124 (20130101) C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976939 | Hall et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Benjamin Hall (State College, Pennsylvania); Jonathan Lynch (Boalsburg, Pennsylvania); Edward W. Reutzel (State College, Pennsylvania); Galen Lynch (Cambridge, Massachusetts) |
ABSTRACT | A laser ablation tomography system includes a specimen stage for supporting a specimen. A specimen axis is defined such that a specimen disposed generally on the axis may be imaged. A laser system is operable to produce a laser sheet in a plane intersecting the specimen axis and generally perpendicular thereto. An imaging system is operable to image the area where the laser sheet intersects the specimen axis. |
FILED | Friday, July 29, 2016 |
APPL NO | 15/223382 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/06 (20130101) Original (OR) Class G01N 21/27 (20130101) G01N 2001/045 (20130101) G01N 2001/2886 (20130101) Image Data Processing or Generation, in General G06T 17/00 (20130101) G06T 2200/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 09975926 | Puckette et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Michael Puckette (Washington, District of Columbia); Max Rasmussen (Washington, District of Columbia); John Neilan (Washington, District of Columbia) |
ABSTRACT | This application is directed generally to minicircle DNA vectors for the vaccination of foot-and-mouth disease (FMD). The transgene expression cassette in the minicircle DNA vector includes: a eukaryotic translation initiation nucleotide sequence, a mutant nucleotide sequence that encodes a foot-and-mouth disease virus (FMDV) capsid polyprotein precursor that contains at least one mutation to eliminate a restriction enzyme recognition site, a nucleotide sequence that encodes a protease that cleaves the FMDV capsid polyprotein precursor into a plurality of FMDV capsid proteins and a translational regulatory element to regulate the expression of the protease. The minicircle DNA vectors can be transfected directly into the cell of a mammalian host. When transfected into the mammalian host cell, virus-like particles can be produced intrinsically to stimulate the mammalian host's immune system to develop adaptive immunity toward foot-and-mouth disease. |
FILED | Tuesday, December 08, 2015 |
APPL NO | 14/962272 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/32122 (20130101) C12N 2770/32123 (20130101) C12N 2770/32134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/09 (20130101) G01N 2469/20 (20130101) G01N 2800/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09977978 | Coulter et al. |
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FUNDED BY |
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APPLICANT(S) | San Diego State University Research Foundation (San Diego, California) |
ASSIGNEE(S) | San Diego State University Research Foundation (San Diego, California) |
INVENTOR(S) | Lloyd Lawrence Arthur Coulter (Escondido, California); Douglas A. Stow (San Diego, California) |
ABSTRACT | A method for collecting and processing remotely sensed imagery in order to achieve precise spatial co-registration (e.g., matched alignment) between multi-temporal image sets is presented. Such precise alignment or spatial co-registration of imagery can be used for change detection, image fusion, and temporal analysis/modeling. Further, images collected in this manner may be further processed in such a way that image frames or line arrays from corresponding photo stations are matched, co-aligned and if desired merged into a single image and/or subjected to the same processing sequence. A second methodology for automated detection of moving objects within a scene using a time series of remotely sensed imagery is also presented. Specialized image collection and preprocessing procedures are utilized to obtain precise spatial co-registration (image registration) between multitemporal image frame sets. In addition, specialized change detection techniques are employed in order to automate the detection of moving objects. |
FILED | Wednesday, November 14, 2012 |
APPL NO | 13/676854 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/3216 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 3/0093 (20130101) G06T 7/33 (20170101) G06T 7/254 (20170101) G06T 2207/10032 (20130101) G06T 2207/30181 (20130101) G06T 2207/30212 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 09976266 | Rosenbaugh et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
ASSIGNEE(S) | NUTECH VENTURES (Lincoln, Nebraska) |
INVENTOR(S) | Scott K. Rosenbaugh (Lincoln, Nebraska); Jennifer D. Schmidt (Eagle, Nebraska); Robert Bielenberg (Lincoln, Nebraska); Ronald K. Faller (Lincoln, Nebraska); Karla A. Lechtenberg (Raymond, Nebraska); John D. Reid (Lincoln, Nebraska); James C. Holloway (Lincoln, Nebraska) |
ABSTRACT | A structural assembly may include a first prefabricated structural element having a first angled face at an end of the first prefabricated structural element; a second prefabricated structural element having a second angled face at an end of the second prefabricated structural element, the end of the second precast barrier segment connected to the end of the first prefabricated structural element; and a coupling assembly connecting the first angled face of the first prefabricated structural element to the second angled face of the second prefabricated structural element. The coupling assembly provides shear and moment continuity across the first and second prefabricated structural elements. This allows for a variable gap due to manufacturing tolerances, construction tolerances, and/or expansion or contraction. |
FILED | Tuesday, April 12, 2016 |
APPL NO | 15/096889 |
ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Additional Work, Such as Equipping Roads or the Construction of Platforms, Helicopter Landing Stages, Signs, Snow Fences, or the Like E01F 15/088 (20130101) Original (OR) Class E01F 15/0407 (20130101) E01F 15/0446 (20130101) E01F 15/0453 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976315 | Pantelides et al. |
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FUNDED BY |
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APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Chris P. Pantelides (Salt Lake City, Utah); Lawrence D. Reaveley (Salt Lake City, Utah) |
ABSTRACT | An elongate member, reinforcement system and associated methods is disclosed. The system can include an elongate member, a structure associated with an end of the elongate member, a support member coupled to the structure and laterally offset from the elongate member extending about an end portion of the elongate member, a support layer surrounding the end portion of the elongate member such that at least a portion of the support member is between the support layer and the elongate member, and a structural filler disposed between the support layer and the elongate member. A load tending to cause relative movement of the end portion of the elongate member and the structure can be transferred through the structural filler and the support member to provide support for the elongate member. |
FILED | Friday, August 08, 2014 |
APPL NO | 14/455570 |
ART UNIT | 3633 — Static Structures, Supports and Furniture |
CURRENT CPC | Scaffolding; Forms; Shuttering; Building Implements or Aids, or Their Use; Handling Building Materials on the Site; Repairing, Breaking-up or Other Work on Existing Buildings E04G 23/0218 (20130101) Original (OR) Class E04G 2023/0251 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/14 (20130101) E04H 9/025 (20130101) E04H 12/12 (20130101) E04H 12/2215 (20130101) Wireless Communication Networks H04W 16/26 (20130101) H04W 24/02 (20130101) H04W 48/12 (20130101) H04W 48/16 (20130101) H04W 52/0219 (20130101) H04W 74/0833 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 09974951 | Ahmed et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation of the City University of New York (New York, New York) |
ASSIGNEE(S) | THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Zaghloul Ahmed (Staten Island, New York); Andrzej Wieraszko (Princeton, New Jersey) |
ABSTRACT | A system and method to treat neuromuscular conditions, including spinal cord injury, by what is characterized as dipole (two point) cortico-muscular stimulation. Two-point stimulation, with oppositely charged electrodes, allows pulsed, direct current to pass through the cortico-muscular pathway. The electrodes are placed on nerves, muscles, or a combination of both, that are on opposite sides of the spinal column, forming a current that passes across the spinal column. Further, an active electrode can be placed on the spinal column and a reference electrode can be placed outside the central nervous system. These methods improve functional recovery of the motor pathway. |
FILED | Tuesday, October 11, 2016 |
APPL NO | 15/290521 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/205 (20130101) Original (OR) Class A61N 1/0551 (20130101) A61N 1/36003 (20130101) A61N 1/36067 (20130101) A61N 1/36071 (20130101) A61N 1/36082 (20130101) A61N 1/36096 (20130101) A61N 1/36103 (20130101) A61N 1/36153 (20130101) A61N 1/36157 (20130101) A61N 1/36171 (20130101) A61N 1/36175 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09976315 | Pantelides et al. |
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FUNDED BY |
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APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Chris P. Pantelides (Salt Lake City, Utah); Lawrence D. Reaveley (Salt Lake City, Utah) |
ABSTRACT | An elongate member, reinforcement system and associated methods is disclosed. The system can include an elongate member, a structure associated with an end of the elongate member, a support member coupled to the structure and laterally offset from the elongate member extending about an end portion of the elongate member, a support layer surrounding the end portion of the elongate member such that at least a portion of the support member is between the support layer and the elongate member, and a structural filler disposed between the support layer and the elongate member. A load tending to cause relative movement of the end portion of the elongate member and the structure can be transferred through the structural filler and the support member to provide support for the elongate member. |
FILED | Friday, August 08, 2014 |
APPL NO | 14/455570 |
ART UNIT | 3633 — Static Structures, Supports and Furniture |
CURRENT CPC | Scaffolding; Forms; Shuttering; Building Implements or Aids, or Their Use; Handling Building Materials on the Site; Repairing, Breaking-up or Other Work on Existing Buildings E04G 23/0218 (20130101) Original (OR) Class E04G 2023/0251 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 9/14 (20130101) E04H 9/025 (20130101) E04H 12/12 (20130101) E04H 12/2215 (20130101) Wireless Communication Networks H04W 16/26 (20130101) H04W 24/02 (20130101) H04W 48/12 (20130101) H04W 48/16 (20130101) H04W 52/0219 (20130101) H04W 74/0833 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 09979401 | Pan et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Chenyun Pan (Atlanta, Georgia); Sourav Dutta (Atlanta, Georgia); Azad Naeemi (Atlanta, Georgia) |
ABSTRACT | Embodiments of the present invention relate generally to logic devices, and more particularly, to magnetoelectric magnetic tunneling junction computational devices. Aspects of the disclosed technology include a stand-alone voltage-controlled magnetoelectric device that satisfies essential requirements for general logic applications, including nonlinearity, gain, concatenability, feedback prevention, and a complete set of Boolean operations based on the majority gate and inverter. Aspects of the present disclosed technology can eliminate the need for any auxiliary FETs to preset or complicated clocking schemes, and prevents the racing condition. |
FILED | Wednesday, July 19, 2017 |
APPL NO | 15/654278 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/14 (20130101) H01F 10/16 (20130101) H01F 10/3218 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/22 (20130101) H01L 43/02 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) Pulse Technique H03K 19/20 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
US 09977644 | Schissler et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Carl Henry Schissler (Carrboro, North Carolina); Dinesh Manocha (Chapel Hill, North Carolina) |
ABSTRACT | Methods, systems, and computer readable media for conducting interactive sound propagation and rending for a plurality of sound sources in a virtual environment scene are disclosed. According to one method, the method includes decomposing a virtual environment scene containing a plurality of sound sources into a plurality of partitions and forming a plurality of source group clusters, wherein each of the source group clusters includes two or more of the sound sources located within a common partition. The method further includes determining, for each of the source group clusters, a single set of sound propagation paths relative to a listener position and generating a simulated output sound at a listener position using sound intensities associated with the determined sets of sound propagation paths. |
FILED | Wednesday, July 29, 2015 |
APPL NO | 14/812785 |
ART UNIT | 2655 — Digital Audio Data Processing |
CURRENT CPC | Electric Digital Data Processing G06F 3/165 (20130101) Original (OR) Class Electrophonic Musical Instruments G10H 2210/136 (20130101) G10H 2210/305 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 27/00 (20130101) Stereophonic Systems H04S 7/30 (20130101) H04S 7/302 (20130101) H04S 7/305 (20130101) H04S 2400/15 (20130101) H04S 2420/07 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 09976123 | Lancaster et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona); The United States Government as Represented by The Department of Veterans Affairs, Department of Vet (Washington, District of Columbia) |
ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
INVENTOR(S) | Jordan Lancaster (Tucson, Arizona); Steve Goldman (Tucson, Arizona) |
ABSTRACT | The present invention provides methods for cellular seeding onto three-dimensional fibroblast constructs, three-dimensional fibroblast constructs seeded with muscle cells, and uses therefore. |
FILED | Thursday, May 21, 2015 |
APPL NO | 14/718309 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/33 (20130101) A61K 35/34 (20130101) A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/367 (20130101) A61L 27/3604 (20130101) A61L 27/3826 (20130101) A61L 2300/64 (20130101) A61L 2430/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0657 (20130101) Original (OR) Class C12N 2502/28 (20130101) C12N 2502/1323 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 09978418 | Estell et al. |
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FUNDED BY |
|
APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
INVENTOR(S) | Timothy William Estell (Ellicott City, Maryland); Bruce Allen Clark (Eldersburg, Maryland); Littleton Kent Riggins (Silver Spring, Maryland); Jeffrey Errol Cade (Elkridge, Maryland); Ronald Franklin Cox (Millersville, Maryland); Martin William Sutton, Jr. (Brooklyn Park, Maryland) |
ABSTRACT | Systems and methods for automating testing of multiple SATA hard drives with multiple motherboards are described herein. In certain embodiments any number of SATA drives may be switchably connected to any number of motherboards, and any number of tests may be performed on combinations of the SATA drives and motherboards without or with only minimal manual intervention between tests. In one embodiment, the system may include an automated selector having a controller adapted to receive a testing instruction and transmit the received testing instruction and a mainboard in communication with the controller. The mainboard may include a logic device to receive the testing instruction from the controller and/or a switch for pairing and unpairing motherboards with SATA storage devices. |
FILED | Monday, October 19, 2015 |
APPL NO | 14/886845 |
ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 11/221 (20130101) G06F 11/0727 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 20/1816 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
US 09977972 | Khan et al. |
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FUNDED BY |
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APPLICANT(S) | SRI International (Menlo Park, California) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Saad Masood Khan (Hamilton, New Jersey); Hui Cheng (Bridgewater, New Jersey); Dennis Lee Matthies (Princeton, New Jersey); Harpreet Singh Sawhney (West Windsor, New Jersey); Sang-Hack Jung (Lawrenceville, New Jersey); Chris Broaddus (Philadelphia, Pennsylvania); Bogdan Calin Mihai Matei (Monmouth Junction, New Jersey); Ajay Divakaran (Monmouth Junction, New Jersey) |
ABSTRACT | A computer implemented method for determining a vehicle type of a vehicle detected in an image is disclosed. An image having a detected vehicle is received. A number of vehicle models having salient feature points is projected on the detected vehicle. A first set of features derived from each of the salient feature locations of the vehicle models is compared to a second set of features derived from corresponding salient feature locations of the detected vehicle to form a set of positive match scores (p-scores) and a set of negative match scores (n-scores). The detected vehicle is classified as one of the vehicle models based at least in part on the set of p-scores and the set of n-scores. |
FILED | Tuesday, October 21, 2014 |
APPL NO | 14/519927 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/123 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/08 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00651 (20130101) G06K 9/00785 (20130101) Original (OR) Class G06K 9/4671 (20130101) G06K 9/6269 (20130101) G06K 9/6282 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/20 (20130101) G06T 2207/10012 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 09976901 | Staver |
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FUNDED BY |
|
APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Neshua, New Hampshire) |
INVENTOR(S) | Philip R Staver (Wilton, New Hampshire) |
ABSTRACT | An optical system with ultra-narrow optical band-pass comprising an objective lens group, and a relay group, having a collimating system, the relay group being in optical communication with the objective lens group. |
FILED | Thursday, August 13, 2015 |
APPL NO | 14/825460 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/26 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 2003/1213 (20130101) Optical Elements, Systems, or Apparatus G02B 1/11 (20130101) G02B 5/26 (20130101) G02B 5/284 (20130101) G02B 13/0095 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 22, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180522.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page