FedInvent™ Patents
Patent Details for Tuesday, May 29, 2018
This page was updated on Monday, March 27, 2023 at 05:33 AM GMT
Department of Health and Human Services (HHS)
US 09980641 | Lathrop et al. |
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FUNDED BY |
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APPLICANT(S) | Kira L. Lathrop (Glenshaw, Pennsylvania); Joel S. Schuman (Pittsburgh, Pennsylvania); Lawrence E. Kagemann (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Kira L. Lathrop (Glenshaw, Pennsylvania); Joel S. Schuman (Pittsburgh, Pennsylvania); Lawrence E. Kagemann (Pittsburgh, Pennsylvania) |
ABSTRACT | The innovation provides for a system and method available to image and visualize the palisades of Vogt via a non-contact process, analyze the image volumes acquired, evaluate the status of the palisades of Vogt from the data represented therein, and display the data in real-time or as a part of a medical record for ongoing consideration and evaluation. |
FILED | Thursday, March 01, 2012 |
APPL NO | 14/001753 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/0025 (20130101) A61B 3/0041 (20130101) A61B 3/102 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02083 (20130101) G01B 9/02091 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980645 | Durand et al. |
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APPLICANT(S) | Dominique M. Durand (Solon, Ohio); Brian Wodlinger (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Dominique M. Durand (Solon, Ohio); Brian Wodlinger (Pittsburgh, Pennsylvania) |
ABSTRACT | A method and an electrode for monitoring electrical activity in a nerve are provided along with a method of fabricating such an electrode. The electrode includes a cuff formed from a chronically-implantable material that, when implanted, extends at least partially around an external periphery of the nerve. A plurality of contacts are supported by the cuff to be arranged adjacent to different regions of the nerve distributed along a transverse direction of the nerve when the cuff is implanted. A multiplexer is coupled to the cuff to be implanted for receiving electrical signals introduced to the contacts by the nerve and multiplexing, in vivo, the electrical signals to be transmitted to an external receiver over a shared communication channel. |
FILED | Thursday, June 21, 2012 |
APPL NO | 13/529514 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0556 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980660 | Rudy et al. |
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APPLICANT(S) | WASHINGTON UNIVERSITY IN ST. LOUIS (St. Louis, Missouri) |
ASSIGNEE(S) | Washington University in St. Louis (St. Louis, Missouri) |
INVENTOR(S) | Yoram Rudy (St. Louis, Missouri); Yong Wang (St. Louis, Missouri) |
ABSTRACT | A non-transitory computer readable medium stores instructions that, when executed by at least one processor, cause the at least one processor to perform a method that includes computing a transfer matrix representing a relative influence that each respective electrode location for measuring electrical potentials on a patient's body has on an estimation of electrical potentials for locations on a surface of interest prior to the measuring of electrical potentials at the respective electrode locations and receiving electrical potential measurements measured via a plurality of electrodes at respective electrode locations on the patient's body. The method also includes computing the estimation of electrical potentials for the locations on the surface of interest based at least in part on the received electrical potential measurements and the computed transfer matrix and generating image data representing the estimation of electrical potentials. |
FILED | Thursday, January 07, 2016 |
APPL NO | 14/990469 |
ART UNIT | 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04012 (20130101) A61B 5/04085 (20130101) Original (OR) Class A61B 5/6805 (20130101) A61B 6/503 (20130101) A61B 6/5247 (20130101) A61B 8/0883 (20130101) A61B 8/5261 (20130101) A61B 2018/00839 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980668 | Strano et al. |
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APPLICANT(S) | Michael S. Strano (Lexington, Massachusetts); Paul W. Barone (Jamaica Plain, Massachusetts); Jin-Ho Ahn (Cambridge, Massachusetts); Kyungsuk Yum (Cambridge, Massachusetts); Thomas P. McNicholas (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Michael S. Strano (Lexington, Massachusetts); Paul W. Barone (Jamaica Plain, Massachusetts); Jin-Ho Ahn (Cambridge, Massachusetts); Kyungsuk Yum (Cambridge, Massachusetts); Thomas P. McNicholas (Cambridge, Massachusetts) |
ABSTRACT | A composition for sensing an analyte can include a photoluminescent nanostructure complexed to a sensing polymer, where the sensing polymer includes an organic polymer non-covalently bound to the photoluminescent nanostructure and an analyte-binding protein covalently bound to the organic polymer, and where the analyte-binding protein is capable of selectively binding the analyte, and the analyte-binding protein undergoes a substantial conformational change when binding the analyte. Separately, a composition for sensing an analyte, can include a complex, where the complex includes a photoluminescent nanostructure in an aqueous surfactant dispersion and a boronic acid capable of selectively reacting with an analyte. The compositions can be used in devices and methods for sensing an analyte. |
FILED | Tuesday, July 31, 2012 |
APPL NO | 13/562403 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1459 (20130101) Original (OR) Class A61B 5/14532 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/66 (20130101) G01N 33/542 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/54373 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980924 | Meyskens et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Frank L. Meyskens (Irvine, California); Ryan W. Dellinger (Azusa, California) |
ABSTRACT | A chemoprotective method for treating, inhibiting or preventing loss of barrier function in skin caused by ultraviolet (UV) light by using an effective amount of pterostilbene is provided. Pharmaceutical and nutraceutical compositions containing pterostilbene suitable for administration to an individual in order to prevent subsequent UV-mediated loss of barrier function in skin are provided. |
FILED | Thursday, September 03, 2015 |
APPL NO | 14/845173 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0014 (20130101) A61K 31/09 (20130101) Original (OR) Class A61K 47/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980925 | Morad et al. |
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APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | Martin Morad (Charleston, South Carolina); Lars Cleemann (Charleston, South Carolina); Juan Jose Arnaiz-Cot (Charleston, South Carolina) |
ABSTRACT | Methods for modulating Ca2+ signaling in cardiac myocytes by use of xanthohumol are described. Xanthohumol can suppress Ca2+ signaling by suppressing spontaneous activity of the RyR2 receptor. Delivery of xanthohumol to a cardiocyte can be utilized in treatment of cardiac arrhythmia. |
FILED | Tuesday, April 25, 2017 |
APPL NO | 15/496022 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) Original (OR) Class A61K 31/137 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980936 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | Emory University (Atlanta, Georgia); The Board of Regents of the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Xingming Deng (Lilburn, Georgia); Jia Zhou (League City, Texas); Chunyong Ding (Galveston, Texas) |
ABSTRACT | The disclosure relates to BH4 inhibitors and therapeutic uses relates thereto. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, comprising administering therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof. |
FILED | Tuesday, May 05, 2015 |
APPL NO | 15/309382 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/336 (20130101) Original (OR) Class A61K 31/439 (20130101) A61K 31/496 (20130101) Acyclic or Carbocyclic Compounds C07C 15/28 (20130101) C07C 233/78 (20130101) C07C 311/18 (20130101) C07C 2101/02 (20130101) C07C 2103/24 (20130101) Heterocyclic Compounds C07D 207/09 (20130101) C07D 207/27 (20130101) C07D 241/04 (20130101) C07D 303/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980942 | Geiger et al. |
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FUNDED BY |
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APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); UNIVERSITAET ULM (Ulm, Germany) |
INVENTOR(S) | Hartmut Geiger (Ulm, Germany); Maria Carolina Florian (Lonsee, Germany); Yi Zheng (Cincinnati, Ohio) |
ABSTRACT | The present invention relates generally to methods and pharmaceutical compositions for rejuvenating hematopoietic stem cells and progenitor cells from blood, intestinal tissue and dermal tissue by administration of at least one inhibitor of a GT-Pase, such as Cdc42 GTPase. |
FILED | Tuesday, April 30, 2013 |
APPL NO | 14/398386 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 35/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5073 (20130101) G01N 2333/914 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980943 | Burkin et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (Reno, Nevada) |
ASSIGNEE(S) | BOARD OF REGENTS OF THE NEVADA SYSTEMS OF HIGHER EDUCATION ON BEHALF OF THE NEVADA, RENO (Reno, Nevada) |
INVENTOR(S) | Dean Burkin (Sparks, Nevada); Ryan Wuebbles (Sparks, Nevada) |
ABSTRACT | Disclosed herein are α7β1 integrin modulatory agents and methods of using such to treat conditions associated with decreased α7β1 integrin expression or activity, including muscular dystrophy. In one example, methods for treating a subject with muscular dystrophy are disclosed. The methods include administering an effective amount of an α7β1 integrin modulatory agent to the subject with muscular dystrophy, wherein the α7β1 integrin modulatory agent increases α7β1 integrin expression or activity as compared to α7β1 integrin expression or activity prior to treatment, thereby treating the subject with muscular dystrophy. Also disclosed are methods of enhancing muscle regeneration, repair, or maintenance in a subject and methods of enhancing α7β1 integrin expression by use of the disclosed α7β1 integrin modulatory agents. Methods of prospectively preventing or reducing muscle injury or damage in a subject are also disclosed. |
FILED | Friday, June 09, 2017 |
APPL NO | 15/619256 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980951 | Schultz et al. |
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APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
INVENTOR(S) | Michael K. Schultz (Iowa City, Iowa); Jessica Reedy (Iowa City, Iowa); Christopher Pigge (Iowa City, Iowa); Moustafa Tarek Ahmed Ibrahim Gabr (Iowa City, Iowa); Mahboubeh Varmazyad (Iowa City, Iowa); Prabhat C. Goswami (Iowa City, Iowa) |
ABSTRACT | The invention provides a method to treat cancer in an animal comprising administering a tetra-arylethylene cation to the animal. |
FILED | Monday, December 19, 2016 |
APPL NO | 15/383983 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/444 (20130101) Original (OR) Class A61K 31/4409 (20130101) A61K 49/0021 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980956 | Vasilakos et al. |
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FUNDED BY |
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APPLICANT(S) | 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | John Vasilakos (Woodbury, Minnesota); Willem Overwijk (Houston, Texas) |
ABSTRACT | Methods and therapeutic combinations useful for increasing cell-mediated anti-tumor responses are described. The methods include administering to a subject a therapeutically effective amount of an Immune Response Modifier Compound and a therapeutically effective amount of one or more immune checkpoint inhibitor compounds. |
FILED | Friday, July 31, 2015 |
APPL NO | 15/500618 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/127 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 47/10 (20130101) A61K 47/44 (20130101) A61K 2039/505 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980962 | Laberge et al. |
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APPLICANT(S) | Buck Institute for Research on Aging (Novato, California); Unity Biotechnology, Inc. (Brisbane, California); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
ASSIGNEE(S) | UNITY BIOTECHNOLOGY, INC (Brisbane, California); BUCK INSTITUTE FOR RESEARCH ON AGING (Novato, California); MAYO FOUNDATION FOR MEDICAL EDUCATIOIN AND RESEARCH (Rochester, Minnesota) |
INVENTOR(S) | Remi-Martin Laberge (San Francisco, California); Judith Campisi (Berkeley, California); Marco Demaria (Groningen, Netherlands); Nathaniel David (San Francisco, California); Darren J. Baker (Rochester, Minnesota); James L. Kirkland (Rochester, Minnesota); Tamar Tchkonia (Rochester, Minnesota); Jan M. A. van Deursen (Rochester, Minnesota); Yi Zhu (Rochester, Minnesota) |
ABSTRACT | Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders. |
FILED | Wednesday, July 12, 2017 |
APPL NO | 15/647688 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0073 (20130101) A61K 31/404 (20130101) A61K 31/428 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/4375 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980969 | Grimaldi et al. |
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FUNDED BY |
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APPLICANT(S) | Southern Research Institute (Birmingham, Alabama) |
ASSIGNEE(S) | SOUTHERN RESEARCH INSTITUTE (Birmingham, Alabama) |
INVENTOR(S) | Maurizio Grimaldi (Birmingham, Alabama); Judith Varady Hobrath (Pinson, Alabama); Subramaniam Ananthan (Birmingham, Alabama); Joseph A. Maddry (Birmingham, Alabama) |
ABSTRACT | The invention provides methods of enhancing memory and/or learning and prevent neurodegeneration, comprising administering therapeutically effective amounts of certain heterocyclic and aromatic compounds to a patient in need thereof. In one aspect, the invention provides methods of treating patients suffering from a neurodegenerative disease, such as but not limited to, Alzheimer's, Parkinsons's, Lou Gehrig's (ALS) disease, and/or memory or learning impairment. The invention further provides neuronal human cell-based assays that assess NF-kB gene upregulation using a luciferase reporter, wherein the assays identify compounds that are useful in enhancing memory or learning. |
FILED | Monday, July 13, 2015 |
APPL NO | 14/797773 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/136 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/444 (20130101) A61K 31/675 (20130101) A61K 31/5377 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980976 | Budunova et al. |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Irina Budunova (Chicago, Illinois); Gleb Baida (Chicago, Illinois); Joel Dudley (Rye, New York) |
ABSTRACT | Disclosed are methods and pharmaceutical compositions for treating diseases, disorders, and conditions associated with glucocorticoid receptor (GR) expression and activity. The disclosed methods typically include administering to a patient in need thereof a glucocorticoid receptor (GR) agonist and administering to the patient in need thereof a REDD1 inhibitor that inhibits expression or activity of REDD1, wherein the REDD1 inhibitor is administered before, concurrently with, or after the GR agonist is administered. |
FILED | Wednesday, February 17, 2016 |
APPL NO | 15/046075 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/56 (20130101) Original (OR) Class A61K 31/58 (20130101) A61K 31/407 (20130101) A61K 31/429 (20130101) A61K 31/436 (20130101) A61K 31/498 (20130101) A61K 31/542 (20130101) A61K 31/573 (20130101) A61K 31/4164 (20130101) A61K 31/7076 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09980982 | Moore et al. |
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APPLICANT(S) | Richard G. Moore (Cranston, Rhode Island); Rakesh K. Singh (Barrington, Rhode Island) |
ASSIGNEE(S) | Women and Infants Hospital of Rhode Island (Providence, Rhode Island) |
INVENTOR(S) | Richard G. Moore (Cranston, Rhode Island); Rakesh K. Singh (Barrington, Rhode Island) |
ABSTRACT | The invention provides compositions and methods for utilizing human epididymal secretion protein E4 (HE4) in the prevention and treatment of cancer and other human diseases. |
FILED | Wednesday, June 06, 2012 |
APPL NO | 14/124595 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/568 (20130101) A61K 31/592 (20130101) A61K 31/592 (20130101) A61K 31/704 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/4745 (20130101) A61K 31/7105 (20130101) A61K 31/7105 (20130101) A61K 33/24 (20130101) Original (OR) Class A61K 38/17 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/47 (20130101) C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 33/57496 (20130101) G01N 2333/811 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981018 | Byzova |
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FUNDED BY |
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APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
INVENTOR(S) | Tatiana Byzova (Pepper Pike, Ohio) |
ABSTRACT | A method of promoting hair growth of a subject includes administering to follicle cells of the subject a therapeutically effective amount of a TLR2 agonist that promotes TLR2 activation and hair growth of the subject. |
FILED | Monday, December 10, 2012 |
APPL NO | 13/709918 |
ART UNIT | 1676 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/4913 (20130101) A61K 38/00 (20130101) A61K 38/385 (20130101) Original (OR) Class A61K 47/64 (20170801) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 7/00 (20130101) A61Q 19/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981020 | Khalili et al. |
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APPLICANT(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
INVENTOR(S) | Kamel Khalili (Bala Cynwyd, Pennsylvania); Wenhui Hu (Cherry Hill, New Jersey) |
ABSTRACT | A method of inactivating a proviral DNA integrated into the genome of a host cell latently infected with a retrovirus by treating the host cell with a composition comprising a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated endonuclease, and two or more different guide RNAs (gRNAs), wherein each of the at least two gRNAs is complementary to a different target nucleic acid sequence in a long terminal repeat (LTR) in the proviral DNA, and inactivating the proviral DNA. A composition for use in inactivating a proviral DNA integrated into the genome of a host cell latently infected with a retrovirus including isolated nucleic acid sequences comprising a CRISPR-associated endonuclease and a guide RNA, wherein the guide RNA is complementary to a target sequence in a human immunodeficiency virus. |
FILED | Friday, May 06, 2016 |
APPL NO | 15/148261 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 35/12 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2320/30 (20130101) C12N 2740/16063 (20130101) Enzymes C12Y 301/21 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981023 | Paulson et al. |
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FUNDED BY |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | James C. Paulson (Del Mar, California); Matthew MacAuley (San Diego, California); David Nemazee (San Diego, California) |
ABSTRACT | The present invention provides liposomal compositions for inducing immune tolerance. The compounds typically comprise a liposome displaying a specific antigen and also a binding moiety for a sialic acid binding Ig-like lectin (Siglec) expressed on B cells. The invention also provides methods for inducing tolerance to a protein or polypeptide antigen (e.g., a protein antigen) in a subject. The methods involve administering to the subject a pharmaceutical composition thatco-presents both the antigen and a glycan ligand for a Siglec expressed on B lymphocytes. |
FILED | Tuesday, December 06, 2016 |
APPL NO | 15/370313 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/001 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) A61K 2039/55555 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981024 | Seavey et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Matthew Seavey (Secane, Pennsylvania); Yvonne Paterson (Philadelphia, Pennsylvania); Paulo Maciag (Long Grove, Illinois); Duane Sewell (Cheltenham, Pennsylvania) |
ABSTRACT | The present invention provides recombinant Listeria strains comprising an angiogenic factor, recombinant polypeptides comprising an angiogenic factor operatively linked to a polypeptide comprising a PEST-like sequence, recombinant nucleotide molecules encoding same, related vaccines, and immunogenic and therapeutic methods utilizing same. |
FILED | Monday, August 01, 2016 |
APPL NO | 15/225205 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/57 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) A61K 2039/585 (20130101) A61K 2039/6037 (20130101) A61K 2039/6068 (20130101) Peptides C07K 14/71 (20130101) C07K 14/195 (20130101) C07K 14/4748 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981027 | Sawada et al. |
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FUNDED BY |
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APPLICANT(S) | IDEMITSU KOSAN CO., LTD. (Chiyoda-ku, Japan); NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Shinjuku-ku, Japan) |
ASSIGNEE(S) | IDEMITSU KOSAN CO., LTD. (Chiyoda-ku, Japan); NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Shinjuku-ku, Japan) |
INVENTOR(S) | Kazutoshi Sawada (Sodegaura, Japan); Takeshi Matsui (Sodegaura, Japan); Eiji Takita (Sodegaura, Japan); Takashi Hamabata (Shinjuku-ku, Japan); Toshio Sato (Shinjuku-ku, Japan) |
ABSTRACT | The present invention provides an agent for controlling colibacillosis including a fusion protein comprising a subunit of Shiga toxin and a subunit of Escherichia coli heat-labile toxin. |
FILED | Tuesday, November 25, 2014 |
APPL NO | 15/039697 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Fodder A23K 20/00 (20160501) A23K 50/30 (20160501) Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) A61K 39/0258 (20130101) A61K 39/0283 (20130101) Original (OR) Class A61K 2039/542 (20130101) A61K 2039/552 (20130101) Peptides C07K 14/25 (20130101) C07K 14/245 (20130101) C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981034 | Huber et al. |
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FUNDED BY |
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APPLICANT(S) | South Dakota Board of Regents (Pierre, South Dakota) |
ASSIGNEE(S) | South Dakota Board of Regents (Vermillion, South Dakota) |
INVENTOR(S) | Victor Huber (Vermillion, South Dakota); Ying Fang (Brookings, South Dakota) |
ABSTRACT | Disclosed herein are compositions and methods useful for immunizing a subject against disease caused by influenza A. Disclosed methods comprise administering to the subject an immunoprotective dose of an immunogenic composition. In certain aspects, the immunogenic composition is a vaccine comprised of a recombinant chimeric hemagglutinin polypeptide. In certain aspects, the subject is a mammal. In further aspects, the mammal is a pig. In still further aspects, the mammal is a human. |
FILED | Monday, April 18, 2016 |
APPL NO | 15/131989 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/55 (20130101) A61K 2039/552 (20130101) A61K 2039/575 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16121 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16141 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981038 | Mazitschek et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Ralph Mazitschek (Belmont, Massachusetts); Balaram Ghosh (Boston, Massachusetts); James Adam Hendricks (Watertown, Massachusetts); Surya Reis (Boston, Massachusetts); Stephen John Haggarty (Dorchester, Massachusetts) |
ABSTRACT | This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same. Provided herein are inhibitors of HDAC having photoswitchable modulators of protein function with short thermal relaxation kinetics. The compounds are diazo compounds including a substituted or unsubstituted aryl or heteroaryl ring, wherein at least one of the rings is substituted with one or more HDAC targeting elements. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/775340 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0028 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 245/08 (20130101) C07C 259/06 (20130101) C07C 259/10 (20130101) Heterocyclic Compounds C07D 333/20 (20130101) C07D 409/14 (20130101) C07D 491/16 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981043 | Portoghese et al. |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); Philip Portoghese (Minneapolis, Minnesota); Akgun Eyup (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Philip Portoghese (Minneapolis, Minnesota); Akgun Eyup (Minneapolis, Minnesota) |
ABSTRACT | The invention provides analgesic conjugates having a mu opioid receptor agonist linked to a mGluR5 antagonist, and to methods for producing analgesia using such compounds. |
FILED | Friday, February 07, 2014 |
APPL NO | 14/766715 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/53 (20130101) A61K 31/445 (20130101) A61K 31/485 (20130101) A61K 31/4168 (20130101) A61K 31/4418 (20130101) A61K 31/4468 (20130101) A61K 47/481 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981048 | Fox et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Ira Jacob Fox (Pittsburgh, Pennsylvania); Aaron W. Bell (West Mifflin, Pennsylvania); Taichiro N. Nishikawa (Pittsburgh, Pennsylvania); Alejandro Soto-Gutierrez (Pittsburgh, Pennsylvania); Yoram Vodovotz (Sewickley, Pennsylvania) |
ABSTRACT | The presently disclosed invention is directed to the discovery that hepatocyte nuclear factor 4 alpha (HNF4α; also known as NR2A1), a transcription factor, reverses hepatocyte dysfunction in an animal model of cirrhosis, resulting in improvement in hepatic function, treatment of cirrhosis, and prolonged survival. |
FILED | Tuesday, February 11, 2014 |
APPL NO | 14/177928 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/05 (20130101) A61K 31/11 (20130101) A61K 31/11 (20130101) A61K 31/085 (20130101) A61K 31/085 (20130101) A61K 31/343 (20130101) A61K 31/343 (20130101) A61K 45/06 (20130101) A61K 48/005 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14141 (20130101) C12N 2750/14171 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981066 | Dimitrievska et al. |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Sashka Dimitrievska (Branford, Connecticut); Laura Niklason (Greenwich, Connecticut) |
ABSTRACT | The present invention provides anti-thrombogenic compositions, including anti-thrombogenic vascular grafts. In certain embodiments, the compositions comprise decellularized tissue coated with an anti-thrombogenic coating. The present invention also provides methods of preparing anti-thrombogenic compositions and methods of treatment comprising implanting the anti-thrombogenic compositions into a subject in need thereof. |
FILED | Monday, May 19, 2014 |
APPL NO | 14/783897 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) A61K 35/44 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/507 (20130101) Original (OR) Class A61L 27/3625 (20130101) A61L 33/08 (20130101) A61L 33/0011 (20130101) A61L 33/0029 (20130101) A61L 33/0064 (20130101) A61L 2300/42 (20130101) A61L 2300/236 (20130101) A61L 2300/608 (20130101) A61L 2420/02 (20130101) A61L 2420/08 (20130101) A61L 2430/40 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 7/54 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981273 | Javanmard et al. |
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FUNDED BY |
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APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Mehdi Javanmard (Fremont, California); Sam Emaminejad (Stanford, California); Janine Mok (Palo Alto, California); Michael N. Mindrinos (Menlo Park, California) |
ABSTRACT | The procedure of dielectric electrophoresis (dielectrophoresis or DEP) utilizes field-polarized particles that move under the application of positive (attractive) and/or negative (repulsive) applied forces. This invention uses negative dielectric electrophoresis (negative dielectrophoresis or nDEP) within a microchannel separation apparatus to make particles move (detached) or remain stationary (attached). In an embodiment of the present invention, the nDEP force generated was strong enough to detach Ag-Ab (antigen-antibody) bonds, which are in the order of 400 pN (piconewtons) while maintaining the integrity of the system components. |
FILED | Monday, September 30, 2013 |
APPL NO | 14/042585 |
ART UNIT | 1759 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 7/023 (20130101) Original (OR) Class B03C 2201/26 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981915 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | GTx, Inc. (Memphis, Tennessee); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); GTx, INC (Memphis, Tennessee) |
INVENTOR(S) | Yan Lu (Bartlett, Tennessee); James T Dalton (Ann Arbor, Michigan); Wei Li (Germantown, Tennessee); Duane D Miller (Collierville, Tennessee) |
ABSTRACT | The present invention relates to colchicine-binding site compounds having anti-cancer activity, compositions comprising the same, and their use for treating various forms of cancer. |
FILED | Tuesday, May 05, 2015 |
APPL NO | 15/309357 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/437 (20130101) A61K 31/4184 (20130101) A61K 31/4184 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 235/18 (20130101) Original (OR) Class C07D 277/24 (20130101) C07D 403/04 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981943 | Hoekstra et al. |
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APPLICANT(S) | Viamet Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina) |
INVENTOR(S) | William J. Hoekstra (Durham, North Carolina); Christopher M. Yates (Raleigh, North Carolina); Mark Behnke (Poolesville, Maryland); Asaf Alimardanov (North Bethesda, Maryland); Scott A. David (Huntsburg, Ohio); Douglas Franklin Fry (Euclid, Ohio) |
ABSTRACT | The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof. |
FILED | Thursday, March 19, 2015 |
APPL NO | 15/126363 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 213/38 (20130101) C07D 401/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981961 | Radu et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Caius G. Radu (Los Angeles, California); Zheng Li (Oakland, California); Raymond M. Gipson (Los Angeles, California); Jue Wang (Los Angeles, California); Nagichettiar Satyamurthy (Los Angeles, California); Arnon Lavie (Chicago, Illinois); Jennifer M. Murphy (Los Angeles, California); David A. Nathanson (Los Angeles, California); Michael E. Jung (Los Angeles, California) |
ABSTRACT | Provided herein are compounds that bind to dCK and methods for treating cancer. |
FILED | Tuesday, January 31, 2017 |
APPL NO | 15/421258 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/426 (20130101) A61K 31/506 (20130101) A61K 31/513 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) C07B 2200/05 (20130101) Heterocyclic Compounds C07D 417/12 (20130101) C07D 417/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981972 | Cravatt et al. |
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FUNDED BY |
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APPLICANT(S) | ABIDE THERAPEUTICS, INC. (San Diego, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
ASSIGNEE(S) | ABIDE THERAPEUTICS, INC. (San Diego, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
INVENTOR(S) | Benjamin F. Cravatt (La Jolla, California); Armand B. Cognetta (San Diego, California); Jonathan J. Hulce (San Diego, California); Micah J. Niphakis (San Diego, California); Todd K. Jones (Solana Beach, California); Cheryl A. Grice (Encinitas, California) |
ABSTRACT | Provided herein are N-hydroxy bicyclic hydantoin carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of serine hydrolases. Furthermore, the subject compounds and compositions are useful for the treatment of one or more of cancer, pain, diabetes, obesity/metabolic syndrome, epilepsy, traumatic brain injury, and inflammation. |
FILED | Wednesday, May 20, 2015 |
APPL NO | 15/313012 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981980 | Vlaar et al. |
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APPLICANT(S) | UNIVERSITY OF PUERTO RICO (San Juan, Puerto Rico) |
ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
INVENTOR(S) | Cornelis P. Vlaar (San Juan, Puerto Rico); Suranganie Dharmawardhane Flanagan (San Juan, Puerto Rico); Eliud Hernandez-O'Farrill (San Juan, Puerto Rico); Linette Castillo-Pichardo (San Juan, Puerto Rico) |
ABSTRACT | Compounds are disclosed that inhibit RhoGTPases that are useful for inhibiting hyperprofilerative and neoplastic diseases. Specifically, the compounds inhibit the GTPases Rac and Cdc42 that are overactive or overexpressed in signaling pathways in cancer and metastasis. Methods for treatment of cancer and hyperproliferative diseases are disclosed. |
FILED | Thursday, April 27, 2017 |
APPL NO | 15/499532 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/04 (20130101) C07D 409/14 (20130101) C07D 491/048 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981981 | Finley et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Daniel J. Finley (Jamaica Plain, Massachusetts); Randall W. King (Brookline, Massachusetts); Byung-Hoon Lee (Cambridge, Massachusetts); Min J. Lee (Jamaica Plain, Massachusetts); Timothy C. Gahman (Encinitas, California) |
ABSTRACT | Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies. |
FILED | Wednesday, December 17, 2014 |
APPL NO | 14/572927 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) C07D 495/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981990 | Janganati et al. |
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FUNDED BY |
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APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas) |
ASSIGNEE(S) | BIOVENTURES, LLC (Little Rock, Arkansas); THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
INVENTOR(S) | Venumadhav Janganati (Little Rock, Arkansas); Peter Crooks (Little Rock, Arkansas); Narsimha Reddy Penthala (Little Rock, Arkansas); Craig Jordan (Denver, Colorado); Shobanbabu Bommagani (Little Rock, Arkansas); Jessica Ponder (Denver, Colorado) |
ABSTRACT | The present disclosure provides dimers of melampomagnolide B (MMB), including carbamate, carbonate, succinic amide, ester and carboxamide dimers of MMB. These derivatives are useful for treating cancer in humans, in particular in treating leukemia, including acute myelogenous leukemia (AML). A compound comprising Formula (1) wherein: Z is independently selected from the group consisting of CH2, O, C(O), and CH, wherein when Z is CH, Z is connected to Y via a double bond and Y is N. |
FILED | Thursday, December 03, 2015 |
APPL NO | 15/532413 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 519/00 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1852 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981997 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents On Behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Peiming Zhang (Gilbert, Arizona); Subhadip Senapati (Tempe, Arizona); Saikat Manna (Tempe, Arizona) |
ABSTRACT | Chemical linkage reagents, methods of making and method of using the same are provided. Chemical linkage reagents according to at least some of the embodiments of the present disclosure may be incorporated into or operatively-linked with affinity molecules for attachment to silicon oxide surfaces to, for example, measure interactions between an affinity molecule and its targeting biomolecules. |
FILED | Tuesday, October 28, 2014 |
APPL NO | 15/033004 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 315/00 (20130101) C07C 317/28 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/10 (20130101) C07F 7/045 (20130101) C07F 7/1836 (20130101) Original (OR) Class C07F 7/1876 (20130101) Peptides C07K 5/126 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/351 (20130101) C12N 2310/3517 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/42 (20130101) G01Q 70/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982009 | Fedeles et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Bogdan I. Fedeles (Cambridge, Massachusetts); Sorin V. Fedeles (Hamden, Connecticut); Robert G. Croy (Belmont, Massachusetts); Stefan Somlo (Westport, Connecticut); John M. Essigmann (Cambridge, Massachusetts) |
ABSTRACT | The present invention provides compounds of Formula (I) or (II), which are thought to be able to inhibit mTOR (mammalian target of rapamycin) signaling pathway, induce UPR (unfolded protein response), and/or perturb mitochondrial function of a cyst cell (e.g., a cyst cell causing polycystic kidney disease (PKD, e.g., autosomal dominant PKD (ADPKD) or autosomal recessive PKD (ARPKD)) or polycystic liver disease (PLD, e.g., autosomal dominant PLD (ADPLD) or autosomal recessive PLD (ARPLD)). The invention also provides pharmaceutical compositions, kits, and methods involving the compounds described herein for use in treating PKD or PLD, inhibiting the growth of a cyst cell, and/or killing a cyst cell. |
FILED | Wednesday, October 15, 2014 |
APPL NO | 14/515441 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/567 (20130101) Steroids C07J 41/0077 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982015 | McInnes et al. |
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FUNDED BY |
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APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | Campbell McInnes (Irmo, South Carolina); Padmavathy Nandha Premnath (Columbia, South Carolina); Joshua K. Bolger (Florence, South Carolina) |
ABSTRACT | Structural and functional analysis of peptide inhibitor binding to the cyclin D and cyclin A groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation. |
FILED | Friday, June 24, 2016 |
APPL NO | 15/192247 |
ART UNIT | 1675 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/06 (20130101) Peptides C07K 5/1024 (20130101) C07K 7/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982020 | Bashkin et al. |
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FUNDED BY |
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APPLICANT(S) | NanoVir LLC (Kalamazoo, Michigan); THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
ASSIGNEE(S) | |
INVENTOR(S) | James K. Bashkin (St. Louis, Missouri); Terri Grace Edwards (Kalamazoo, Michigan); Christopher Fisher (Kalamazoo, Michigan); George D. Harris, Jr. (Chesterfield, Missouri); Kevin J. Koeller (Richmond Heights, Missouri) |
ABSTRACT | The present invention relates to polyamide compounds and their use in pharmaceutical compositions and in medical applications for the treatment of human papillomavirus infections and/or polyomavirus infections. |
FILED | Wednesday, August 05, 2015 |
APPL NO | 14/818881 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/02 (20130101) C07K 14/00 (20130101) Original (OR) Class C07K 14/001 (20130101) C07K 14/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982023 | Ware et al. |
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FUNDED BY |
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APPLICANT(S) | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (San Diego, California) |
ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
INVENTOR(S) | Carl F. Ware (La Jolla, California); John Sedy (La Jolla, California) |
ABSTRACT | Ligand-specific HVEM variants, compositions comprising such variants, and methods of treating inflammatory diseases comprising administering such variants, are provided. |
FILED | Thursday, November 15, 2012 |
APPL NO | 13/677703 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/03 (20130101) Original (OR) Class C07K 14/70578 (20130101) C07K 16/28 (20130101) C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982025 | O'Keefe et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Barry R. O'Keefe (Frederick, Maryland); Alexander Wlodawer (Frederick, Maryland); Tinoush Moulaei (College Park, Maryland) |
ABSTRACT | The invention provides a construct containing two or more monomeric griffithsin molecules, optionally joined by a linker, as well as conjugate comprising the construct, a nucleic acid encoding the construct or conjugate, vectors, and cells. A nucleic acid encoding the polypeptide or fusion protein, as well as compositions or cells comprising the polypeptide, fusion protein, or nucleic acid also are provided. |
FILED | Thursday, June 05, 2014 |
APPL NO | 14/895349 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/481 (20130101) A61K 47/4823 (20130101) A61K 47/48215 (20130101) A61K 47/48246 (20130101) A61K 47/48284 (20130101) A61K 47/48338 (20130101) Peptides C07K 14/405 (20130101) Original (OR) Class C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982026 | Lifton et al. |
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FUNDED BY |
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APPLICANT(S) | Richard P. Lifton (North Haven, Connecticut); Bixiao Zhao (Plainsboro, New Jersey); Murim Choi (Seoul, South Korea); Goran Akerstrom (Uppsala, Sweden); Gunnar Westin (Uppsala, Sweden); Peyman Bjorklund (Stockholm, Sweden); Per Hellman (Uppsala, Sweden) |
ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
INVENTOR(S) | Richard P. Lifton (North Haven, Connecticut); Bixiao Zhao (Plainsboro, New Jersey); Murim Choi (Seoul, South Korea); Goran Akerstrom (Uppsala, Sweden); Gunnar Westin (Uppsala, Sweden); Peyman Bjorklund (Stockholm, Sweden); Per Hellman (Uppsala, Sweden) |
ABSTRACT | The present invention relates to the discovery that mutations in KCNJ5 are associated with adrenal diseases and disorders. The invention includes compositions and methods for the assessment, characterization and treatment of adrenal diseases and disorders, based upon the presence or absence of a KCNJ5 mutation that is associated with an adrenal disease or disorder. |
FILED | Wednesday, January 04, 2012 |
APPL NO | 13/978098 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/06 (20130101) A61K 51/00 (20130101) Peptides C07K 14/435 (20130101) Original (OR) Class C07K 14/705 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982034 | Wilcox et al. |
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FUNDED BY |
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APPLICANT(S) | PLATELET TARGETED THERAPEUTICS, LLC (Brookfield, Wisconsin) |
ASSIGNEE(S) | PLATELET TARGETED THERAPEUTICS, LLC (Brookfield, Wisconsin) |
INVENTOR(S) | David A. Wilcox (Brookfield, Wisconsin); Sandra L. Haberichter (Greenfield, Wisconsin) |
ABSTRACT | The present disclosure relates to compositions and methods for targeting expression of exogenous genes to platelets. In particular, the present disclosure relates to treatment of hemophilia and other diseases and conditions by targeting expression of exogenous agents (e.g., clotting factors) to platelets. |
FILED | Thursday, October 24, 2013 |
APPL NO | 14/437457 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 48/0058 (20130101) A61K 2035/124 (20130101) Peptides C07K 14/755 (20130101) Original (OR) Class C07K 14/7055 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982037 | Raguram et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | S. Raguram (Hillsborough, New Jersey); Viswanathan Sasisekharan (Cambridge, Massachusetts); Venkataramanan Soundararajan (Windham, New Hampshire); Ram Sasisekharan (Lexington, Massachusetts); Vidya Subramanian (Somerville, Massachusetts); Kannan Tharakaraman (Woburn, Massachusetts) |
ABSTRACT | The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza. |
FILED | Monday, May 15, 2017 |
APPL NO | 15/595407 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982038 | Chan et al. |
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FUNDED BY |
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APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
INVENTOR(S) | Yee-Peng Chan (Bethesda, Maryland); Christopher C. Broder (Silver Spring, Maryland) |
ABSTRACT | The present invention relates to antibodies or antibody fragments that bind, neutralize, and/or inhibit Hendra or Nipah virus. The invention provides antibodies or antibody fragments that selectively bind to the F glycoprotein of Hendra or Nipah virus, and pharmaceutical compositions including such antibodies and/or fragments. The invention further provides polynucleotides encoding the antibodies and fragments of the invention and host cells transformed therewith. Additionally, the invention discloses prophylactic, therapeutic, and diagnostic methods employing the antibodies, fragments, polynucleotides, and/or compositions of the invention. |
FILED | Friday, January 23, 2015 |
APPL NO | 15/112913 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/1027 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982241 | Picker et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Louis Picker (Portland, Oregon); Jay A. Nelson (Lake Oswego, Oregon); Klaus Frueh (Portland, Oregon); Michael A. Jarvis (Portland, Oregon); Scott G. Hansen (Portland, Oregon) |
ABSTRACT | The recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors of this invention encode heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread. |
FILED | Thursday, October 01, 2015 |
APPL NO | 14/872756 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/08 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/13 (20130101) A61K 39/145 (20130101) A61K 39/275 (20130101) A61K 2039/58 (20130101) A61K 2039/552 (20130101) A61K 2039/572 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 14/16 (20130101) C07K 14/045 (20130101) C07K 14/161 (20130101) C07K 14/162 (20130101) C07K 14/163 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/869 (20130101) C12N 2710/16111 (20130101) C12N 2710/16134 (20130101) C12N 2710/16141 (20130101) C12N 2710/16143 (20130101) C12N 2710/16162 (20130101) C12N 2710/16171 (20130101) C12N 2710/24134 (20130101) C12N 2740/15022 (20130101) C12N 2740/15034 (20130101) C12N 2760/14134 (20130101) C12N 2760/16134 (20130101) C12N 2770/32634 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982260 | Kendall et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
INVENTOR(S) | Genevieve C. Kendall (Los Angeles, California); Stanley F. Nelson (Los Angeles, California); M. Carrie Miceli (Los Angeles, California) |
ABSTRACT | This invention relates, e.g., to a method for enhancing exon skipping in a pre-mRNA of interest, comprising contacting the pre-mRNA with an effective amount of a compound such as, for example, Perphenazine, Flupentixol DiHCl, Zuclopenthixol or Corynanthine HCl, or a compound which shares a similar 2-D structure and activity level with one of these compounds, or a pharmaceutically acceptable salt, hydrate, solvate, or isomer of the compound, and, optionally, with an antisense oligonucleotide that is specific for a splicing sequence in the pre-mRNA Methods for treating Duchenne muscular dystrophy (DMD) are disclosed. |
FILED | Tuesday, September 30, 2014 |
APPL NO | 15/025952 |
ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/475 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 31/5415 (20130101) A61K 31/5415 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/321 (20130101) C12N 2310/346 (20130101) C12N 2310/3521 (20130101) C12N 2320/31 (20130101) C12N 2320/31 (20130101) C12N 2320/33 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982276 | Shayakhmetov et al. |
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FUNDED BY |
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APPLICANT(S) | ADCURE BIOTECHNOLOGIES, LLC. (Snellville, Georgia) |
ASSIGNEE(S) | ADCURE BIOTECHNOLOGIES, LLC. (Snellville, Georgia) |
INVENTOR(S) | Dmitry M. Shayakhmetov (Snellville, Georgia); Nelson C. Di Paolo (Avondale Estates, Georgia) |
ABSTRACT | The present invention describes generation and the use of adenovirus variants (Ad) possessing modified capsid penton base protein where mutations in the penton based RGD loop are made to avoid Ad binding to cellular β3-integrins. Specifically, the ablation of Ad penton base interaction with cellular β3-integrins results in reduced activation of inflammation after intravenous Ad administration. Further, the introduction into penton RGD loop of non-RGD containing peptides, which mediate virus entry into the cell via new cellular receptors, allows for the efficient Ad-mediated gene delivery into target cells in vivo after intravascular virus administration and triggers significantly reduced toxicity associated with Ad injection. |
FILED | Friday, March 11, 2016 |
APPL NO | 15/067839 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/10022 (20130101) C12N 2710/10043 (20130101) C12N 2710/10045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982288 | Shimada et al. |
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FUNDED BY |
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APPLICANT(S) | THE NEMOURS FOUNDATION (Jacksonville, Florida) |
ASSIGNEE(S) | THE NEMOURS FOUNDATION (Jacksonville, Florida) |
INVENTOR(S) | Tsutomu Shimada (Wilmington, Delaware); Shunji Tomatsu (Wilmington, Delaware) |
ABSTRACT | Provided is a rapid screening method for detecting mucopolysaccharidosis IVA and mucopolysaccharidosis VII. Biological samples containing glycosaminoglycans are enzymatically digested to converts chondroitin 6-sulfate into ΔDi-6S. ΔDi-6S is assayed by liquid chromatography-tandem mass spectroscopy analysis. Elevated ΔDi-6S, and thus elevated chondroitin 6-sulfate present in the sample, indicates a likelihood that the test subject is afflicted with mucopolysaccharidosis IVA or mucopolysaccharidosis VII. |
FILED | Thursday, April 30, 2015 |
APPL NO | 14/700667 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) C12Q 1/44 (20130101) C12Q 1/527 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/916 (20130101) G01N 2333/938 (20130101) G01N 2400/40 (20130101) G01N 2800/042 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982290 | Janzen et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
INVENTOR(S) | William Perry Janzen (Chapel Hill, North Carolina); Samantha Gail Pattenden (Mebane, North Carolina); Chatura Nadisha Jayakody (Morrisville, North Carolina); Jason Eric Streeter (Chapel Hill, North Carolina); Paul Alexander Dayton (Carrboro, North Carolina); Cameron Champion Wood (Raleigh, North Carolina); Siddharth Kaup Shenoy (Durham, North Carolina) |
ABSTRACT | Methods and systems for using encapsulated microbubbles to process biological samples are disclosed. According to one aspect, a method for using encapsulated microbubbles to process a biological sample includes creating a mixture comprising encapsulated microbubbles mixed with a biological sample and adding activation energy to the mixture to cause at least some of the microbubbles to oscillate or burst and thereby process the sample, including effecting cell lysis, shearing DNA, and/or performing tissue dispersion. |
FILED | Friday, October 04, 2013 |
APPL NO | 14/432747 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1003 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 2001/387 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982301 | Muthukumar et al. |
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FUNDED BY |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Thangamani Muthukumar (New York, New York); Manikkam Suthanthiran (Scarsdale, New York); Ruchuang Ding (Beechurst, New York) |
ABSTRACT | Non-invasive methods for detecting, predicting, and/or monitoring differential diagnosis of kidney transplant dysfunction in kidney transplant patients are described. |
FILED | Wednesday, January 07, 2015 |
APPL NO | 14/591542 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982303 | Rothenberg |
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FUNDED BY |
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APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
INVENTOR(S) | Marc E. Rothenberg (Cincinnati, Ohio) |
ABSTRACT | The disclosure provides methods and compositions for diagnosing a patient eosinophilic esophagitis, the methods based upon the patient's gene expression profile for a panel of genes. The methods can also be used to exclude a diagnosis of chronic esophagitis. |
FILED | Friday, April 15, 2016 |
APPL NO | 15/130162 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982304 | Vogelstein et al. |
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FUNDED BY |
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APPLICANT(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Bel Air, Maryland); Victor Velculescu (Dayton, Maryland); Nickolas Papadopoulos (Towson, Maryland); Sian Jones (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Bel Air, Maryland); Victor Velculescu (Dayton, Maryland); Nickolas Papadopoulos (Towson, Maryland); Sian Jones (Baltimore, Maryland) |
ABSTRACT | Two genes, ARID1A (AT-rich interactive domain-containing protein 1A) and PPP2R1A (protein-phosphatase 2, regulatory subunit 1, alpha), can be used in methods which are useful for detecting cancer, diagnosing cancer, contributing to a diagnosis of cancer, confirming a diagnosis of cancer, identifying appropriate treatments for cancer, monitoring treatment of cancer, and evaluating treatment protocols for cancer, including ovarian clear cell carcinoma, breast cancer, colon cancer, gastric cancer, lung cancer, medulloblastoma, pancreatic cancer, and prostate cancer. |
FILED | Tuesday, September 06, 2011 |
APPL NO | 13/819933 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) A61K 31/7088 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982306 | Yan et al. |
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FUNDED BY |
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APPLICANT(S) | Hai Yan (Chapel Hill, North Carolina); Darell Bigner (Mebane, North Carolina); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Alan Meeker (Pikesville, Maryland); Ralph Hruban (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Luis Diaz (Ellicott City, Maryland); Yuchen Jiao (Baltimore, Maryland) |
ASSIGNEE(S) | Duke University (Durham, North Carolina); The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Hai Yan (Chapel Hill, North Carolina); Darell Bigner (Mebane, North Carolina); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Alan Meeker (Pikesville, Maryland); Ralph Hruban (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Luis Diaz (Ellicott City, Maryland); Yuchen Jiao (Baltimore, Maryland) |
ABSTRACT | We determined the sequence of ATRX and DAXX in 447 cancers from various sites. We found mutations most commonly in pediatric glioblastoma multiformae (GBM) (11.1%), adult GBM (6.5%), oligodendrogliomas (7.7%) and medulloblastomas (1.5%); and showed that Alternative Lengthening of Telomeres (ALT), a telomerase-independent telomere maintenance mechanism found in cancers that have not activated telomerase, perfectly correlated with somatic mutations of either gene. In contrast, neuroblastomas, and adenocarcinomas of the ovary, breast, and pancreas were negative for mutations in ATRX and DAXX. Alterations in ATRX or DAXX define a specific molecular pathway that is closely associated with an alternative telomere maintenance function in human cancers. |
FILED | Thursday, June 28, 2012 |
APPL NO | 14/129850 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983058 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | YuHuang Wang (Laurel, Maryland); Hyejin Kwon (Greenbelt, Maryland); Mijin Kim (Silver Spring, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | YuHuang Wang (Laurel, Maryland); Hyejin Kwon (Greenbelt, Maryland); Mijin Kim (Silver Spring, Maryland) |
ABSTRACT | The present invention relates to near-infrared quantum emitters, and in particular carbon nanostructures with chemically incorporated fluorescent defects, and methods of synthesizing near-infrared emitting nanostructures. |
FILED | Tuesday, May 09, 2017 |
APPL NO | 15/590397 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/128 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 49/006 (20130101) H01L 51/5262 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983107 | Hansma et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Paul K. Hansma (Goleta, California); Connor Randall (Santa Barbara, California); Daniel Bridges (Goleta, California) |
ABSTRACT | The field of the invention generally relates to probes, related devices and methods for measuring material properties. In an embodiment, the present invention provides a test probe for use in a reference point indentation device. The test probe has an end proximal to a tip and an end distal to the tip. The distal end of the test probe has a self-centering mate comprising a countersink of about 90 degrees to about 100 degrees to a depth of between 0.010 in. and 0.035 in. |
FILED | Monday, July 22, 2013 |
APPL NO | 14/392010 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0053 (20130101) A61B 5/4504 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/04 (20130101) G01N 3/40 (20130101) Original (OR) Class G01N 3/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983110 | Kopelman et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Raoul Kopelman (Ann Arbor, Michigan); Mark A. Burns (Ann Arbor, Michigan); Yunzi Li (Ann Arbor, Michigan) |
ABSTRACT | The disclosure provides a label-free viscosity-based analyte detection system using paramagnetic beads as an asynchronous magnetic bead rotation (AMBR) microviscometer. It is disclosed herein that the bead rotation period is linearly proportional to the viscosity of a solution comprising analytes surrounding the paramagnetic bead. Optical measurement of asynchronous microbead motion determines solution viscosity precisely in microscale volumes, thus allowing an estimate of analyte concentration. The results demonstrate the feasibility of viscosity-based analyte detection using AMBR in microscale aqueous volumes. |
FILED | Tuesday, November 04, 2014 |
APPL NO | 14/532907 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2527/153 (20130101) C12Q 2563/137 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/10 (20130101) G01N 11/165 (20130101) Original (OR) Class G01N 2011/0086 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983194 | Bar-Sagi et al. |
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FUNDED BY |
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APPLICANT(S) | Dafna Bar-Sagi (Miller Place, New York); Cosimo Commisso (New York, New York); Rengin G. Soydaner-Azeloglu (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Dafna Bar-Sagi (Miller Place, New York); Cosimo Commisso (New York, New York); Rengin G. Soydaner-Azeloglu (New York, New York) |
ABSTRACT | The present invention is directed to methods of inhibiting both proliferation and survival of cancer cells and for treating a subject having cancer. The present invention is further directed to methods of diagnosing cancer in a subject and identifying cancer therapeutics. |
FILED | Monday, April 02, 2012 |
APPL NO | 14/009013 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/352 (20130101) A61K 31/366 (20130101) A61K 31/407 (20130101) A61K 31/435 (20130101) A61K 31/685 (20130101) A61K 31/4178 (20130101) A61K 31/4965 (20130101) A61K 31/5377 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5005 (20130101) Original (OR) Class G01N 33/5011 (20130101) G01N 2800/7028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983200 | Pavan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | William J. Pavan (Derwood, Maryland); Jorge L. Rodriguez (Bethesda, Maryland); Denise M. Larson (Bethesda, Maryland); Forbes D. Porter, III (Gaithersburg, Maryland) |
ABSTRACT | The present invention features diagnostic compositions and methods for predicting the age of onset of a lysosomal storage disease or a disease associated with a lysosomal defect in subject. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/776440 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) Original (OR) Class G01N 33/582 (20130101) G01N 33/6893 (20130101) G01N 33/6896 (20130101) G01N 2500/10 (20130101) G01N 2800/04 (20130101) G01N 2800/52 (20130101) G01N 2800/2821 (20130101) G01N 2800/2835 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983210 | Wong et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | David T. W. Wong (Beverly Hills, California); Maie A. R. St. John (Los Angeles, California); Yang Li (Los Angeles, California) |
ABSTRACT | A method to detect a biomarker in saliva wherein the biomarker is an extracellular mRNA, comprises detecting the extracellular mRNA in the cell-free saliva; transcriptome analysis of saliva comprises detecting a transcriptome pattern in the cell-free saliva; a method to detect genetic alterations in an organ or in a gene in the organ by analyzing saliva, comprises detecting a transcriptome pattern and/or the mRNA profiling of the gene in cell-free saliva; a method to diagnose an oral or systemic pathology disease or disorder in a subject, comprises: detecting profile of a biomarker associated with the pathology disease or disorder, in particular mRNA and/or protein, in cell-free saliva and/or serum; kits comprising identifier for at least one biomarker for performing at least one of the methods; and use of salivary biomarker salivary and/or serum mRNAs as biomarkers for oral and/or systemic pathology, disease or disorder. |
FILED | Tuesday, February 18, 2014 |
APPL NO | 14/182672 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5017 (20130101) G01N 33/6893 (20130101) G01N 33/57488 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983215 | Speicher et al. |
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FUNDED BY |
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APPLICANT(S) | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (Philadelphia, Pennsylvania); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | David W. Speicher (Berwyn, Pennsylvania); Kurt T. Barnhart (Bryn Mawr, Pennsylvania); Lynn A. Beer (Medford, New Jersey) |
ABSTRACT | Methods and compositions are provided for diagnosing ectopic pregnancy in a mammalian subject by detecting changes in expression of the selected genes, gene fragments or transcripts or expression products, or changes in the expression levels of one or more of proteins or peptide fragments, identified in Table 2 and FIGS. 8 and 9 herein. A selected gene, gene transcript or protein/peptide expression product, or profiles or signatures formed by combinations of same, detected in a biological fluid, preferably sera, of a subject, enables comparison of the corresponding genes, proteins or profiles from that of a reference or control having a normal intrauterine pregnancy. Detection of characteristic changes in the gene profile or protein expression signature of the subject is correlated with a diagnosis of ectopic pregnancy. Various compositions for use in such diagnosis include PCR primer-probe sets or ligands, labeled or immobilized, which are capable of detecting the changes in expression or translation of these targets. |
FILED | Wednesday, December 21, 2016 |
APPL NO | 15/386714 |
ART UNIT | 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2333/471 (20130101) G01N 2333/70503 (20130101) G01N 2560/00 (20130101) G01N 2800/368 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983217 | Bowser et al. |
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FUNDED BY |
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APPLICANT(S) | Dignity Health (Phoenix, Arizona) |
ASSIGNEE(S) | Dignity Health (Phoenix, Arizona) |
INVENTOR(S) | Robert Bowser (Scottsdale, Arizona); Mahlon Collins (Phoenix, Arizona) |
ABSTRACT | The invention relates to diagnosis, prognosis and treatment of neurological diseases. In one embodiment, the present invention provides methods and kits that diagnose whether a subject has a neurological disease or susceptibility to a neurological disease by evaluating nuclear stress body (NSB) levels. Further described are methods and kits that prognose a neurological disease in a subject by monitoring changes in NSB levels. Also described are methods and kits that treat neurological diseases by administering one or more inhibitors of NSB signaling to a patient, as well as compositions containing one or more NSB signaling inhibitors. Medical conditions suitable with various embodiments of the invention include but are not limited to ALS, FTLD, dementia and AD. |
FILED | Friday, November 07, 2014 |
APPL NO | 15/028680 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/18 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2800/28 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09983285 — High spatial and temporal resolution dynamic contrast-enhanced magnetic resonance imaging
US 09983285 | Hu et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Peng Hu (Los Angeles, California); Stanislas Rapacchi (Los Angeles, California) |
ABSTRACT | A method for high spatial and temporal resolution dynamic contrast enhanced magnetic resonance imaging using a random subsampled Cartesian k-space using a Poisson-disk random pattern acquisition strategy and a compressed sensing reconstruction algorithm incorporating magnitude image subtraction is presented. One reconstruction uses a split-Bregman minimization of the sum of the L1 norm of the pixel-wise magnitude difference between two successive temporal frames, a fidelity term and a total variation (TV) sparsity term. |
FILED | Monday, May 11, 2015 |
APPL NO | 14/709089 |
ART UNIT | 3777 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4822 (20130101) G01R 33/5601 (20130101) Original (OR) Class G01R 33/5611 (20130101) G01R 33/5635 (20130101) Image Data Processing or Generation, in General G06T 11/006 (20130101) G06T 2207/10096 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983397 | Horstmeyer et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Roarke W. Horstmeyer (Palo Alto, California); Guoan Zheng (Vernon, Connecticut); Xiaoze Ou (Pasadena, California); Changhuei Yang (South Pasadena, California) |
ABSTRACT | Certain aspects pertain to aperture-scanning Fourier ptychographic imaging devices comprising an aperture scanner that can generate an aperture at different locations at an intermediate plane of an optical arrangement, and a detector that can acquire lower resolution intensity images for different aperture locations, and wherein a higher resolution complex image may be constructed by iteratively updating regions in Fourier space with the acquired lower resolution images. |
FILED | Monday, July 11, 2016 |
APPL NO | 15/206859 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/205 (20130101) Measurement of Nuclear or X-radiation G01T 1/185 (20130101) G01T 3/008 (20130101) Optical Elements, Systems, or Apparatus G02B 21/006 (20130101) G02B 21/008 (20130101) Original (OR) Class G02B 21/16 (20130101) G02B 21/0032 (20130101) G02B 21/0048 (20130101) G02B 21/0056 (20130101) G02B 21/367 (20130101) Pictorial Communication, e.g Television H04N 13/0459 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983399 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Yang Liu (Sewickley, Pennsylvania); Hoa Vinh Pham (Pittsburgh, Pennsylvania); Shikhar Fnu (Pittsburgh, Pennsylvania) |
ABSTRACT | Provided are systems, methods, and other embodiments associated with depth-resolved spatial-domain low-coherence quantitative phase microscopy for high-throughput analysis of 3D nanoscale architectural alterations in unstained tissue and cells. A spatial-domain low-coherence quantitative phase microscopy apparatus includes a drOPD mapping module, a transmission phase imaging module, and a bright-field and transmission phase imaging module. The drOPD mapping module includes a reflection-mode low-coherence spectral interferometry for drOPD mapping of unstained tissue. The transmission phase imaging module includes transmission quantitative phase imaging of unstained and stained tissue and produce an image registration reference. The bright-field and transmission phase imaging module includes bright-field imaging of H&E-stained tissue for nuclei identification and pathology correlation. |
FILED | Friday, February 26, 2016 |
APPL NO | 15/055222 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Optical Elements, Systems, or Apparatus G02B 21/12 (20130101) G02B 21/14 (20130101) G02B 21/0056 (20130101) G02B 21/367 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/337 (20170101) G06T 2207/10028 (20130101) G06T 2207/10056 (20130101) G06T 2207/30024 (20130101) Pictorial Communication, e.g Television H04N 13/0022 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984283 | Davatzikos et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Christos Davatzikos (Philadelphia, Pennsylvania); Ke Zeng (Philadelphia, Pennsylvania); Ali Guray Erus (Philadelphia, Pennsylvania) |
ABSTRACT | Methods, systems, and computer readable media for automated detection of abnormalities in medical images are disclosed. According to a method for automated abnormality detection, the method includes receiving a target image. The method also includes deformably registering to the target image or to a common template a subset of normative images from a plurality of normative images, wherein the subset of normative images is associated with a normal variation of an anatomical feature. The method further includes defining a dictionary using the subset of normative images. The method also includes decomposing, using sparse decomposition and the dictionary, the target image. The method further includes classifying one or more voxels of the target image as normal or abnormal based on results of the sparse decomposition. |
FILED | Tuesday, February 16, 2016 |
APPL NO | 15/044928 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00288 (20130101) Original (OR) Class G06K 9/6247 (20130101) G06K 9/6284 (20130101) G06K 2009/4695 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0014 (20130101) G06T 7/0016 (20130101) G06T 7/337 (20170101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/30016 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984464 | Jia et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Yali Jia (Portland, Oregon); David Huang (Portland, Oregon); Li Liu (Portland, Oregon) |
ABSTRACT | Disclosed are systems and methods to automatically detect choroidal neovascularization (CNV) in the outer retina using OCT angiography. Further disclosed are methods of removing projection artifacts from the outer retina and for combining brightness, orientation, and position information in a context-aware saliency model to quantify CNV area in OCT angiograms. |
FILED | Friday, September 29, 2017 |
APPL NO | 15/721070 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) Original (OR) Class G06T 7/136 (20170101) G06T 2207/10101 (20130101) G06T 2207/20036 (20130101) G06T 2207/20192 (20130101) G06T 2207/30041 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984773 | Gondhalekar et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Ravi L. Gondhalekar (Cambridge, Massachusetts); Francis J. Doyle, III (Cambridge, Massachusetts); Eyal Dassau (Cambridge, Massachusetts) |
ABSTRACT | A state-estimator for the estimation or initialization of the state of a discrete-time state-space dynamical model based on sensor measurements of the model output, comprising fitting a continuous-time function to acquired sensor measurement data-points of each model output, and subsequently sampling the continuous time function at exactly the sample-period of the state-space dynamic model for which the state is being estimated or initialized, in order to construct a model state via a synthesized output trajectory. |
FILED | Saturday, February 04, 2017 |
APPL NO | 15/424824 |
ART UNIT | 2123 — AI & Simulation/Modeling |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) A61M 2005/14208 (20130101) A61M 2205/18 (20130101) A61M 2205/50 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 19/3406 (20130101) G06F 19/3437 (20130101) G06F 19/3468 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) G16H 50/50 (20180101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 09981010 | Davis et al. |
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FUNDED BY |
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APPLICANT(S) | Baylor College of Medicine (Houston, Texas); William Marsh Rice University (Houston, Texas) |
ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas); William Marsh Rice University (Houston, Texas) |
INVENTOR(S) | Alan R. Davis (Missouri City, Texas); Elizabeth A. Davis (Missouri City, Texas); Kevin Moran (Spring, Texas); Ronke M. Olabisi (Piscataway, New Jersey); Jennifer L. West (Durham, North Carolina); Christy Franco (Houston, Texas) |
ABSTRACT | A method and system to induce bone growth by locally delivering bone morphogenetic proteins (BMPs) to the target location for a prolonged period without invasive procedures are disclosed. The new bone growth is induced by delivering cells producing BMPs from transduced viral vectors to the target cite. In various embodiments, the cells are encapsulated in hydrogel microspheres that are non-degradable or degradable by enzymes produced during the bone formation process. Various embodiments may be used to induce spinal fusion or repair critical bone defects. |
FILED | Monday, January 12, 2015 |
APPL NO | 14/594701 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1641 (20130101) A61K 9/5031 (20130101) A61K 35/32 (20130101) A61K 35/33 (20130101) A61K 38/1875 (20130101) Original (OR) Class A61K 2035/128 (20130101) Peptides C07K 14/51 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0652 (20130101) C12N 2510/02 (20130101) C12N 2533/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981240 | Roper et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Christopher S Roper (Santa Monica, California); Adam F. Gross (Santa Monica, California) |
ABSTRACT | Methods to fabricate tightly packed arrays of nanoparticles are disclosed, without relying on organic ligands or a substrate. In some variations, a method of assembling particles into an array comprises dispersing particles in a liquid solution; introducing a triggerable pH-control substance capable of generating an acid or a base; and triggering the pH-control substance to generate an acid or a base within the liquid solution, thereby titrating the pH. During pH titration, the particle-surface charge magnitude is reduced, causing the particles to assemble into a particle array. Other variations provide a device for assembling particles into particle arrays, comprising a droplet-generating microfluidic region; a first-fluid inlet port; a second-fluid inlet port; a reaction microfluidic region, disposed in fluid communication with the droplet-generating microfluidic region; and a trigger source configured to trigger generation of an acid or a base from at least one pH-control substance contained within the reaction microfluidic region. |
FILED | Friday, August 19, 2016 |
APPL NO | 15/241661 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/0075 (20130101) B01J 2219/00331 (20130101) B01J 2219/00585 (20130101) B01J 2219/00599 (20130101) B01J 2219/00686 (20130101) B01J 2219/00754 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 2200/0647 (20130101) B01L 2200/0673 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0062 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/02 (20130101) C01G 49/0045 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/16 (20130101) C01P 2004/40 (20130101) C01P 2004/61 (20130101) C01P 2004/62 (20130101) C01P 2004/64 (20130101) C01P 2004/80 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/10 (20130101) C30B 7/14 (20130101) C30B 29/12 (20130101) C30B 29/22 (20130101) C30B 29/62 (20130101) C30B 33/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981267 | Hart et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Sean J. Hart (Keswick, Virginia); Sarah J. R. Staton (Washington, District of Columbia); Alexander V. Terray (Alexandria, Virginia); Gregory E. Collins (Huntingtown, Maryland) |
ABSTRACT | The combined value of integrating optical forces and electrokinetics allows for the pooled separation vectors of each to be applied, providing for separation based on combinations of features such as size, shape, refractive index, charge, charge distribution, charge mobility, permittivity, and deformability. The interplay of these separation vectors allow for the selective manipulation of analytes with a finer degree of variation. Embodiments include methods of method of separating particles in a microfluidic channel using a device comprising a microfluidic channel, a source of laser light focused by an optic into the microfluidic channel, and a source of electrical field operationally connected to the microfluidic channel via electrodes so that the laser light and the electrical field to act jointly on the particles in the microfluidic channel. Other devices and methods are disclosed. |
FILED | Wednesday, June 15, 2016 |
APPL NO | 15/183531 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0652 (20130101) B01L 2300/0864 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) B01L 2400/0424 (20130101) B01L 2400/0454 (20130101) B01L 2400/0487 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/1081 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981314 | Folgar et al. |
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FUNDED BY |
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APPLICANT(S) | 3D SYSTEMS, INC. (Rock Hill, South Carolina) |
ASSIGNEE(S) | 3D Systems, Inc. (Rock Hill, South Carolina) |
INVENTOR(S) | Luis N. Folgar (Lake Oswego, Oregon); Christian E. Folgar (Langhorne, Pennsylvania) |
ABSTRACT | There are provided techniques for direct printing material into parts made by additive manufacturing, such as parts made by laser sintering. The direct printed material may be a metal, elastomer, ceramic, or any other material. Further, the direct printed material is typically different than the laser sintering material. Other aspects of the invention include using direct printed materials in the laser sintered parts to improve part strength, provide multi-materials, selectively provide electrical conductivity, and/or provide other desirable features to the parts. |
FILED | Monday, November 28, 2016 |
APPL NO | 15/362181 |
ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) B22F 7/02 (20130101) Original (OR) Class B22F 2003/1056 (20130101) B22F 2301/10 (20130101) B22F 2301/255 (20130101) B22F 2302/45 (20130101) B22F 2302/253 (20130101) B22F 2998/10 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/0077 (20130101) B29C 67/0081 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/251 (20130101) B29K 2995/0005 (20130101) B29K 2995/0007 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 80/00 (20141201) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 5/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981377 | Morin et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Stephen A. Morin (Arlington, Massachusetts); Robert F. Shepherd (Brooktondale, New York); Adam Stokes (Watertown, Massachusetts); Filip Ilievski (Santa Clara, California); Ramses V. Martinez (Somerville, Massachusetts); Jamie L. Branch (Topeka, Kansas); Carina R. Fish (Cambridge, Massachusetts); Lihua Jin (Somerville, Massachusetts); Rui M. D. Nunes (Somerville, Massachusetts); Zhigang Suo (Lexington, Massachusetts); George M. Whitesides (Newton, Massachusetts) |
ABSTRACT | Systems and methods for providing flexible robotic actuators are disclosed. Some embodiments of the disclosed subject matter include a soft robot capable of providing a radial deflection motions; a soft tentacle actuator capable of providing a variety of motions and providing transportation means for various types of materials; and a hybrid robotic system that retains desirable characteristics of both soft robots and hard robots. Some embodiments of the disclosed subject matter also include methods for operating the disclosed robotic systems. |
FILED | Monday, September 08, 2014 |
APPL NO | 14/480106 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Domestic Washing or Cleaning; Suction Cleaners in General A47L 9/2836 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) Original (OR) Class B25J 9/1075 (20130101) B25J 9/1697 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/22 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/20305 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981459 | Gibson et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel J. Gibson (Cheverly, Maryland); Mikhail Kotov (Silver Spring, Maryland); Geoff Chin (Arlington, Virginia); Shyam S. Bayya (Ashburn, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Daniel J. Gibson (Cheverly, Maryland); Mikhail Kotov (Silver Spring, Maryland); Geoff Chin (Arlington, Virginia); Shyam S. Bayya (Ashburn, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
ABSTRACT | A method for bonding infrared transmitting glasses into an optical element without interlayer voids by stacking at least two different infrared transmitting glasses inside a vessel where each glass has a different refractive index, a different dispersion, or both, and where the glasses all have similar viscosities, thermal expansion coefficients, and glass transition temperatures; placing a weight on top of the stack; applying a vacuum to the vessel; applying an isostatic pressure of at least 1500 psi; and after releasing the isostatic pressure, annealing at a temperature within 10° C. of the glass transition temperature at a pressure between 0 and 1000 psi. Applying the vacuum, applying the isostatic pressure, and annealing are done sequentially and with no intermediate transitions to ambient temperature or pressure. Also disclosed is the related optical element made by this method. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/210828 |
ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 17/06 (20130101) B32B 33/00 (20130101) B32B 37/003 (20130101) B32B 37/0007 (20130101) B32B 37/18 (20130101) B32B 37/144 (20130101) B32B 37/1009 (20130101) Original (OR) Class B32B 37/1018 (20130101) B32B 38/0036 (20130101) B32B 2037/0092 (20130101) B32B 2037/268 (20130101) B32B 2038/0048 (20130101) B32B 2307/412 (20130101) B32B 2307/418 (20130101) B32B 2309/022 (20130101) B32B 2309/62 (20130101) B32B 2309/68 (20130101) B32B 2309/125 (20130101) B32B 2315/08 (20130101) B32B 2551/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981887 | Laskoski et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Matthew Laskoski (Springfield, Virginia); Teddy M. Keller (Fairfax Station, Virginia) |
ABSTRACT | A method of: reacting a dihydroxybenzene with bromine to form a bromodihydroxybenzene; reacting the bromodihydroxybenzene with trifluoromethanesulfonyl chloride or trifluoromethanesulfonic anhydride to form a bromotrifluoromethanesulfonatobenzene; and reacting the bromotrifluoromethanesulfonatobenzene with phenylacetylene to form a phenylethynylbenzene. |
FILED | Wednesday, January 10, 2018 |
APPL NO | 15/867009 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 2/868 (20130101) Original (OR) Class C07C 37/62 (20130101) C07C 303/28 (20130101) C07C 2531/22 (20130101) C07C 2531/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982009 | Fedeles et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Bogdan I. Fedeles (Cambridge, Massachusetts); Sorin V. Fedeles (Hamden, Connecticut); Robert G. Croy (Belmont, Massachusetts); Stefan Somlo (Westport, Connecticut); John M. Essigmann (Cambridge, Massachusetts) |
ABSTRACT | The present invention provides compounds of Formula (I) or (II), which are thought to be able to inhibit mTOR (mammalian target of rapamycin) signaling pathway, induce UPR (unfolded protein response), and/or perturb mitochondrial function of a cyst cell (e.g., a cyst cell causing polycystic kidney disease (PKD, e.g., autosomal dominant PKD (ADPKD) or autosomal recessive PKD (ARPKD)) or polycystic liver disease (PLD, e.g., autosomal dominant PLD (ADPLD) or autosomal recessive PLD (ARPLD)). The invention also provides pharmaceutical compositions, kits, and methods involving the compounds described herein for use in treating PKD or PLD, inhibiting the growth of a cyst cell, and/or killing a cyst cell. |
FILED | Wednesday, October 15, 2014 |
APPL NO | 14/515441 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/567 (20130101) Steroids C07J 41/0077 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982038 | Chan et al. |
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FUNDED BY |
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APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
INVENTOR(S) | Yee-Peng Chan (Bethesda, Maryland); Christopher C. Broder (Silver Spring, Maryland) |
ABSTRACT | The present invention relates to antibodies or antibody fragments that bind, neutralize, and/or inhibit Hendra or Nipah virus. The invention provides antibodies or antibody fragments that selectively bind to the F glycoprotein of Hendra or Nipah virus, and pharmaceutical compositions including such antibodies and/or fragments. The invention further provides polynucleotides encoding the antibodies and fragments of the invention and host cells transformed therewith. Additionally, the invention discloses prophylactic, therapeutic, and diagnostic methods employing the antibodies, fragments, polynucleotides, and/or compositions of the invention. |
FILED | Friday, January 23, 2015 |
APPL NO | 15/112913 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/1027 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982209 | Junk et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC (Gainesville, Florida) |
INVENTOR(S) | Christopher P. Junk (Wilmington, Delaware); Gregory Scott Blackman (Media, Pennsylvania); Steven R. Lustig (Landenberg, Pennsylvania); Mark D. Wetzel (Newark, Delaware); Wallace Gregory Sawyer (Gainesville, Florida); Brandon A. Krick (Gainesville, Florida) |
ABSTRACT | A low-wear fluoropolymer composite body comprises at least one fluoropolymer and additive particles dispersed therein. Also provided is a process for the fabrication of such a fluoropolymer composite body. The composite body exhibits a low wear rate for sliding motion against a hard counterface, and may be formulated with either melt-processible or non-melt-processible fluoropolymers. |
FILED | Friday, December 20, 2013 |
APPL NO | 14/136672 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/303 (20130101) C04B 26/08 (20130101) C04B 26/08 (20130101) C04B 35/117 (20130101) C04B 2111/00008 (20130101) C04B 2111/00362 (20130101) C04B 2235/444 (20130101) C04B 2235/3217 (20130101) C04B 2235/5454 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/22 (20130101) C08K 2003/2227 (20130101) C08K 2201/005 (20130101) Compositions of Macromolecular Compounds C08L 27/18 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 107/38 (20130101) C10M 125/10 (20130101) Original (OR) Class C10M 2201/062 (20130101) C10M 2201/062 (20130101) C10M 2201/062 (20130101) C10M 2201/105 (20130101) C10M 2213/043 (20130101) C10M 2213/0623 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2210/03 (20130101) C10N 2210/04 (20130101) C10N 2220/082 (20130101) C10N 2230/06 (20130101) C10N 2240/02 (20130101) C10N 2250/08 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/201 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/25 (20150115) Y10T 428/256 (20150115) Y10T 428/257 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982227 | Rao et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
ASSIGNEE(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
INVENTOR(S) | Govind Rao (Ellicott City, Maryland); Yordan Kostov (Columbia, Maryland); Leah Tolosa (Columbia, Maryland); Xudong Ge (Woodstock, Maryland); Douglas Frey (Ellicott City, Maryland) |
ABSTRACT | A portable and mobile bioprocessing system and method for protein manufacturing that is compact, integrated and suited for on-demand production of any type of proteins and for delivery of the produced proteins to patients or for assay purposes. The portable system and method can also be used for efficient on-demand production of any type of protein with point-of-care delivery. |
FILED | Monday, April 11, 2016 |
APPL NO | 15/095305 |
ART UNIT | 1675 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/12 (20130101) C12M 47/10 (20130101) Original (OR) Class C12M 47/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982260 | Kendall et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
INVENTOR(S) | Genevieve C. Kendall (Los Angeles, California); Stanley F. Nelson (Los Angeles, California); M. Carrie Miceli (Los Angeles, California) |
ABSTRACT | This invention relates, e.g., to a method for enhancing exon skipping in a pre-mRNA of interest, comprising contacting the pre-mRNA with an effective amount of a compound such as, for example, Perphenazine, Flupentixol DiHCl, Zuclopenthixol or Corynanthine HCl, or a compound which shares a similar 2-D structure and activity level with one of these compounds, or a pharmaceutically acceptable salt, hydrate, solvate, or isomer of the compound, and, optionally, with an antisense oligonucleotide that is specific for a splicing sequence in the pre-mRNA Methods for treating Duchenne muscular dystrophy (DMD) are disclosed. |
FILED | Tuesday, September 30, 2014 |
APPL NO | 15/025952 |
ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/475 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 31/5415 (20130101) A61K 31/5415 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/321 (20130101) C12N 2310/346 (20130101) C12N 2310/3521 (20130101) C12N 2320/31 (20130101) C12N 2320/31 (20130101) C12N 2320/33 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982304 | Vogelstein et al. |
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FUNDED BY |
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APPLICANT(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Bel Air, Maryland); Victor Velculescu (Dayton, Maryland); Nickolas Papadopoulos (Towson, Maryland); Sian Jones (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Bel Air, Maryland); Victor Velculescu (Dayton, Maryland); Nickolas Papadopoulos (Towson, Maryland); Sian Jones (Baltimore, Maryland) |
ABSTRACT | Two genes, ARID1A (AT-rich interactive domain-containing protein 1A) and PPP2R1A (protein-phosphatase 2, regulatory subunit 1, alpha), can be used in methods which are useful for detecting cancer, diagnosing cancer, contributing to a diagnosis of cancer, confirming a diagnosis of cancer, identifying appropriate treatments for cancer, monitoring treatment of cancer, and evaluating treatment protocols for cancer, including ovarian clear cell carcinoma, breast cancer, colon cancer, gastric cancer, lung cancer, medulloblastoma, pancreatic cancer, and prostate cancer. |
FILED | Tuesday, September 06, 2011 |
APPL NO | 13/819933 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) A61K 31/7088 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982403 | Price |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by The Secretary of The Army (Washington, District of Columbia) |
INVENTOR(S) | Christopher G. Price (Vicksburg, Mississippi) |
ABSTRACT | A vehicle barrier apparatus includes a horizontal barrier component, a vertical barrier component, at least one rigid stabilizer beam having two end surfaces and at least one elongated side surface. One end of the stabilizer beam is affixed to the vertical barrier component. The elongated side surface of the stabilizer beam is affixed to the horizontal barrier component to prevent rotational movement of the vertical barrier component. A lower surface of the horizontal barrier component is a friction-enhanced surface which creates a sliding friction interface upon contact of a moving vehicle with the vertical barrier component. The horizontal barrier is made up of panel components interconnected by link components. |
FILED | Monday, May 16, 2016 |
APPL NO | 15/156065 |
ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Additional Work, Such as Equipping Roads or the Construction of Platforms, Helicopter Landing Stages, Signs, Snow Fences, or the Like E01F 13/02 (20130101) E01F 13/12 (20130101) Original (OR) Class E01F 13/123 (20130101) E01F 15/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982542 | Lewis et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Scott D. Lewis (Vernon, Connecticut); Christopher Corcoran (Manchester, Connecticut) |
ABSTRACT | An airfoil structure for a gas turbine engine includes an airfoil which includes a leading edge and a trailing edge. A platform is located adjacent a first end of the airfoil and includes a core passage that extends through the platform, a mate-face for engaging an adjacent airfoil structure and a set of impingement cooling holes in communication with the core passage that extend through the mate-face adjacent the trialing edge of the airfoil. |
FILED | Friday, July 17, 2015 |
APPL NO | 14/802459 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) F01D 5/187 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2260/201 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982543 | Spangler |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Brandon W. Spangler (Vernon, Connecticut) |
ABSTRACT | An airfoil of a gas turbine engine having a hollow body defining at least one airfoil cavity therein, the hollow body defining an inner diameter and an outer diameter and a baffle positioned within the at least one airfoil cavity and extending over less than an entire length between the inner diameter and the outer diameter, the baffle configured to reduce the cross-sectional area within the at least one airfoil cavity. The at least one airfoil cavity includes a first portion having a length that is defined by an open cavity having a full cross-sectional area and a second portion having a length that is defined by a reduced cross-sectional area, the second portion being the length of the baffle within the at least one airfoil cavity. |
FILED | Wednesday, August 05, 2015 |
APPL NO | 14/818379 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class F01D 5/188 (20130101) F01D 5/189 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2260/20 (20130101) F05D 2260/201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
09982553 — Seal assembly including a notched seal element for arranging between a stator and a rotor
US 09982553 | Miller |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Jonathan L. Miller (Ware, Massachusetts) |
ABSTRACT | A seal assembly with an axis is provided that includes a rotor and a seal element that is connected to a stator with an anti-rotation element. The seal element includes a first element surface, a second element surface and an annular notch. The first element surface axially engages the stator. The second element surface radially engages the rotor. The notch extends into the seal element between the first and the second element surfaces. The stator radially overlaps a portion of the notch. |
FILED | Monday, January 06, 2014 |
APPL NO | 14/771964 |
ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/003 (20130101) F01D 11/08 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Non-positive-displacement Pumps F04D 29/10 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) F05D 2250/182 (20130101) F05D 2260/38 (20130101) Pistons; Cylinders; Sealings F16J 15/26 (20130101) F16J 15/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982790 | Saunders et al. |
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FUNDED BY |
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APPLICANT(S) | Google Inc. (Mountain View, California) |
ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
INVENTOR(S) | John Aaron Saunders (Arlington, Massachusetts); Steve Potter (Bedford, Massachusetts); Haink Tu (Waltham, Massachusetts); Zachary Jackowski (Somerville, Massachusetts); Alex Khripin (Cambridge, Massachusetts) |
ABSTRACT | Examples are provided that describe a rotary hydraulic valve. In one example, a rotary valve comprises a sleeve with a plurality of selector ports and one or more control ports spaced along a length of the sleeve. A spool comprising an internal chamber is provided within the sleeve. The spool includes a plurality of selector openings and one or more control openings spaced along a length of the spool. The rotary valve also comprises a controller for determining a given rotational movement of the spool based on a selection of a pressurized fluid. The rotary valve also comprises a motor coupled to the spool and for rotating the spool within the sleeve based on the given rotational movement. The motor is configured to cause a given alignment of the spool to the sleeve resulting in a pathway through the internal chamber of the spool and out to the sleeve. |
FILED | Wednesday, December 31, 2014 |
APPL NO | 14/587822 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/0833 (20130101) Original (OR) Class F16K 31/042 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/86654 (20150401) Y10T 137/87298 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983012 | Young et al. |
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FUNDED BY |
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APPLICANT(S) | TRX Systems, Inc. (Greenbelt, Maryland) |
ASSIGNEE(S) | TRX SYSTEMS, INC. (Greenbelt, Maryland) |
INVENTOR(S) | Travis Young (Rockville, Maryland); Kamiar Kordari (McLean, Virginia); Benjamin Funk (Hanover, Maryland); Carole Teolis (Glenn Dale, Maryland) |
ABSTRACT | A location and mapping service is described that creates a global database of indoor navigation maps through crowd-sourcing and data fusion technologies. The navigation maps consist of a database of geo-referenced, uniquely described features in the multi-dimensional sensor space (e.g., including structural, RF, magnetic, image, acoustic, or other data) that are collected automatically as a tracked mobile device is moved through a building (e.g. a person with a mobile phone or a robot). The feature information can be used to create building models as one or more tracked devices traverse a building. |
FILED | Thursday, April 14, 2016 |
APPL NO | 15/099361 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/32 (20130101) G01C 21/165 (20130101) G01C 21/206 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0252 (20130101) G01S 19/13 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983055 | Estes |
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FUNDED BY |
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APPLICANT(S) | Lee E Estes (Mattapoisett, Massachusetts) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Lee E Estes (Mattapoisett, Massachusetts) |
ABSTRACT | The present invention provides a meter and method of use for measuring an optical attenuation coefficient in a liquid medium. In operation, a collimated beam, produced by a laser of the attenuation meter apparatus, propagates thru the liquid medium with filtered back-scattered light arriving at a camera of the meter. A light image is formed at a focal plane of the camera. The light image is recorded and analyzed by a microcomputer to provide optical beam attenuations coefficients. |
FILED | Thursday, September 28, 2017 |
APPL NO | 15/718106 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) Original (OR) Class G01J 1/0488 (20130101) G01J 2001/4247 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983058 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | YuHuang Wang (Laurel, Maryland); Hyejin Kwon (Greenbelt, Maryland); Mijin Kim (Silver Spring, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | YuHuang Wang (Laurel, Maryland); Hyejin Kwon (Greenbelt, Maryland); Mijin Kim (Silver Spring, Maryland) |
ABSTRACT | The present invention relates to near-infrared quantum emitters, and in particular carbon nanostructures with chemically incorporated fluorescent defects, and methods of synthesizing near-infrared emitting nanostructures. |
FILED | Tuesday, May 09, 2017 |
APPL NO | 15/590397 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/128 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 49/006 (20130101) H01L 51/5262 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983089 | Kauffman |
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FUNDED BY |
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APPLICANT(S) | University of Dayton (Dayton, Ohio) |
ASSIGNEE(S) | University of Dayton (Dayton, Ohio) |
INVENTOR(S) | Robert E. Kauffman (Centerville, Ohio) |
ABSTRACT | A persistent color change liquid indicator includes a backing layer, a penetration layer, and a reaction layer. The backing layer has an indication color. The penetration layer includes a liquid structure to allow a liquid to travel through the penetration layer to the reaction layer. The penetration layer is opaque when dry and translucent when exposed to the liquid is to allow the indication color to be visible. The reaction layer reacts to the presence of the liquid such that the visibility of the indication color persists after exposure to the liquid ceases. |
FILED | Monday, April 11, 2016 |
APPL NO | 15/095396 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 2201/30 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983111 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Chang-Jin Kim (Beverly Hills, California); Muchen Xu (Los Angeles, California) |
ABSTRACT | A low-profile shear-sensing unit includes a floating plate surrounded by a frame and a displacement sensor that measures in-plane movement of the floating plate. Covered with a surface sample, the floating plate is displaced by the friction drag (i.e., shear) on the surface caused by the flow of fluid and the in-plane displacement is measured by the displacement sensor. The shear force on the sample surface is then obtained by multiplying the measured displacement and the spring constant of the flexure beams, which suspend the floating plate. The floating plate and the flexure beams are formed out of one plate or substrate to achieve monolithic construction with a beam geometry that leads to a high-resolution measurement. |
FILED | Friday, November 18, 2016 |
APPL NO | 15/356062 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 13/02 (20130101) Original (OR) Class G01N 2013/0216 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983132 | Diebold et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Eric D. Diebold (Los Angeles, California); Bahram Jalali (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
ABSTRACT | Apparatus and methods for fluorescence imaging using radiofrequency multiplexed excitation. One apparatus splits an excitation laser beam into two arms of a Mach-Zehnder interferometer. The light in the first beam is frequency shifted by an acousto-optic deflector, which is driven by a phase-engineered radiofrequency comb designed to minimize peak-to-average power ratio. This RF comb generates multiple deflected optical beams possessing a range of output angles and frequency shifts. The second beam is shifted in frequency using an acousto-optic frequency shifter. After combining at a second beam splitter, the two beams are focused to a line on the sample using a conventional laser scanning microscope lens system. The acousto-optic deflectors frequency-encode the simultaneous excitation of an entire row of pixels, which enables detection and de-multiplexing of fluorescence images using a single photomultiplier tube and digital phase-coherent signal recovery techniques. |
FILED | Wednesday, July 27, 2016 |
APPL NO | 15/221065 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/05 (20130101) G01N 21/6408 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 2021/6415 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0076 (20130101) G02B 21/0084 (20130101) G02B 27/1006 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/11 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983162 | Chaum et al. |
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APPLICANT(S) | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (Memphis, Tennessee) |
ASSIGNEE(S) | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (Memphis, Tennessee) |
INVENTOR(S) | Edward Chaum (Memphis, Tennessee); Erno Lindner (Germantown, Tennessee); Jidong Guo (Chungdhun, China PRC) |
ABSTRACT | The present invention is directed to an electrochemical sensor involving an electrode and a coating that surrounds the electrode, the coating comprising a structural component, a water immiscible solvent, a resistance decreasing component, and an ion exchange component, wherein the coating selectively partitions an electrochemically active drug from a fluid or vapor sample whereby an electrochemical signal within the coating can be measured using the electrode. Devices and methods for using this electrochemical sensor are also disclosed. |
FILED | Thursday, March 14, 2013 |
APPL NO | 14/404674 |
ART UNIT | 1759 — Optics |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/1723 (20130101) A61M 2202/048 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/333 (20130101) G01N 27/3275 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983183 | Motayed et al. |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia); George Mason University (Fairfax, Virginia); The George Washington University (Washington, District of Columbia) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia); George Mason University (Fairfax, Virginia); The George Washington University (Washington, District of Columbia) |
INVENTOR(S) | Abhishek Motayed (Rockville, Maryland); Geetha Aluri (Clifton Park, New York); Albert V. Davydov (North Potomac, Maryland); Mulpuri V. Rao (Fairfax Station, Virginia); Vladimir P. Oleshko (Gaithersburg, Maryland); Ritu Bajpai (Santa Clara, California); Mona E. Zaghloul (Bethesda, Maryland); Brian Thomson (Washington, District of Columbia); Baomei Wen (Gaithersburg, Maryland); Ting Xie (Burtonsville, Maryland); Guannan Liu (Portland, Oregon); Ratan Debnath (Damascus, Maryland) |
ABSTRACT | A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte. |
FILED | Wednesday, October 19, 2016 |
APPL NO | 15/297693 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 33/004 (20130101) G01N 33/005 (20130101) G01N 33/0031 (20130101) G01N 33/0037 (20130101) G01N 33/0042 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) G01N 33/0049 (20130101) G01N 33/0054 (20130101) G01N 33/0057 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/245 (20180101) Y02A 50/246 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983209 | Lancaster et al. |
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APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
INVENTOR(S) | Johnathan M. Lancaster (Tampa, Florida); Douglas C. Marchion (Seminole, Florida); Yin Xiong (Tampa, Florida) |
ABSTRACT | The present invention relates to the BAD pathway's influence on development, progression, chemo-sensitivity, and overall survival for multiple human cancers and its potential as a therapeutic target to increase chemo-sensitivity. BAD pathway expression was associated with the development and/or progression of breast, colon, and endometrial cancers, relapse-free survival from breast cancer, and overall survival from ovarian, colon, and brain cancers. Expression was also associated with in vitro sensitivity to a range of cytotoxic agents. pBAD levels were higher in cancer versus immortalized normal cells and chemo-resistant versus—sensitive cancer cells and associated with increased cell proliferation. |
FILED | Monday, November 10, 2014 |
APPL NO | 14/537521 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 33/57415 (20130101) G01N 33/57419 (20130101) G01N 33/57442 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 33/57496 (20130101) G01N 2800/52 (20130101) G01N 2800/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983260 | Yurt et al. |
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FUNDED BY |
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APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia) |
INVENTOR(S) | Abdulkadir Yurt (Brighton, Massachusetts); Selim M. Unlu (Boston, Massachusetts); Bennett B. Goldberg (Newton, Massachusetts); Euan Ramsay (Dublin, California) |
ABSTRACT | A dual-phase interferometric method and device for charge modulation mapping in integrated circuits provides significant improvement in signal to noise ratio over conventional detection configurations. The method and device can be used for failure analysis and testing of advanced technology IC chips for which high sensitivity in modulation mapping is required. |
FILED | Friday, October 11, 2013 |
APPL NO | 14/433732 |
ART UNIT | 2867 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/41 (20130101) G01N 21/1717 (20130101) G01N 2021/1719 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 1/071 (20130101) G01R 31/26 (20130101) G01R 31/311 (20130101) Original (OR) Class G01R 31/2601 (20130101) G01R 31/2851 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983354 | Ptasinski et al. |
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FUNDED BY |
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APPLICANT(S) | Joanna Ptasinski (San Diego, California); Stephen Russell (San Diego, California) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Joanna Ptasinski (San Diego, California); Stephen Russell (San Diego, California) |
ABSTRACT | Methods and devices for a plasmonic circuit are described. A planar plasmonic device is configured with a controlling gate structure and when coupled to a complementary plasmonic device, a switching circuit can be realized. Also, by varying the properties of the complementary plasmonic device, the circuit can also operate as an amplifier. By use of combinations of this plasmonic circuit element, more advanced circuits and logic functions can be arrived at. |
FILED | Thursday, April 10, 2008 |
APPL NO | 12/100512 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/1226 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983359 | Luo et al. |
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FUNDED BY |
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APPLICANT(S) | Oracle International Corporation (Redwood Shores, California) |
ASSIGNEE(S) | Oracle International Corporation (Redwood Shores, California) |
INVENTOR(S) | Ying Luo (San Diego, California); Xuezhe Zheng (San Diego, California); Jin Yao (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
ABSTRACT | An integrated circuit that includes a wavelength-filter layer stack (which may include silicon oxynitride) and an optical substrate (such as a silicon-on-insulator platform) is described. During operation, an optical signal received from an optical fiber or an optical waveguide is wavelength filtered into a set of wavelength-filter optical waveguides by an optical multiplexer/demultiplexer (such as an Echelle grating and/or an array waveguide grating) in the wavelength-filter layer stack. Then, wavelength-filtered optical signals are optically coupled to the optical substrate, where they are received using photodetectors. Alternatively, modulators in the optical substrate modulate wavelength-filtered modulated optical signals, which are then optically coupled to the set of wavelength-filter optical waveguides in the wavelength-filter layer stack. Next, the wavelength-filtered modulated optical signals are combined using the optical multiplexer/demultiplexer, and the resulting optical signal is output to the optical fiber or the optical waveguide. |
FILED | Thursday, August 24, 2017 |
APPL NO | 15/685716 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) G02B 6/1228 (20130101) G02B 6/2938 (20130101) G02B 6/29361 (20130101) G02B 6/29397 (20130101) Original (OR) Class G02B 2006/12097 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983382 | Griffin et al. |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Steven F. Griffin (Kihei, Hawaii); Brandoch Calef (Kihei, Hawaii) |
ABSTRACT | An aperture partitioning element for an imaging system is disclosed. The aperture partitioning element includes a plurality of segments each including a reflective surface and a body. The plurality of segments are each independently moveable in at least one of an x-axis, a y-axis, and a z-axis of the aperture partitioning element. The aperture partitioning element also includes at least one positioner received within the body of a corresponding segment. The at least one positioner is actuated to move the corresponding segment in at least one of the x-axis, the y-axis, and the z-axis. |
FILED | Monday, January 12, 2015 |
APPL NO | 14/594227 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/1827 (20130101) Original (OR) Class G02B 26/06 (20130101) G02B 27/0068 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983420 | Amberg et al. |
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FUNDED BY |
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APPLICANT(S) | Oracle International Corporation (Redwood City, California) |
ASSIGNEE(S) | ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California) |
INVENTOR(S) | Philip Amberg (San Jose, California); Eric Y. Chang (San Mateo, California); Xuezhe Zheng (San Diego, California); Frankie Y. Liu (Palo Alto, California); Ronald Ho (Mountain View, California); Ashok V. Krishnamoorthy (San Diego, California) |
ABSTRACT | In the optical device, a ring-resonator modulator, having an adjustable resonance (center) wavelength, optically couples an optical signal that includes the carrier wavelength from an input optical waveguide to an output optical waveguide. A monitoring mechanism in the optical device, which is optically coupled to the output optical waveguide, monitors a performance metric of an output optical signal from the output waveguide. For example, the monitoring mechanism may monitor: an average optical power associated with the output optical signal, and/or an amplitude of the output optical signal. Moreover, control logic in the optical device adjusts the resonance wavelength based on the monitored performance metric so that the performance metric is optimized. |
FILED | Thursday, October 16, 2014 |
APPL NO | 14/516301 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) Original (OR) Class G02F 1/0147 (20130101) G02F 2201/58 (20130101) G02F 2203/15 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983479 | Tabirian et al. |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia); Beam Engineering for Advanced Measurements Co. (Orlando, Florida) |
ASSIGNEE(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Nelson V. Tabirian (Winter Park, Florida); Sarik R. Nersisyan (Maitland, Florida); Brian R. Kimball (Shrewsbury, Massachusetts); Diane M. Steeves (Franklin, Massachusetts) |
ABSTRACT | An apparatus and method for fabricating high quality one- or two-dimensional diffractive waveplates and arrays that exhibit high diffraction efficiency and capable of inexpensive large volume production. A generally non-holographic and aperiodic polarization converter for converting the polarization of a coherent input light beam of a visible wavelength into a pattern of continuous spatial modulation at the output of the polarization converter. A photoresponsive material characterized by an anisotropy axis according to polarization of the light beam is exposed to a polarization modulation pattern and coated subsequently with an anisotropic material overlayer with ability of producing an optical axis orientation according to and under the influence of the anisotropy axis of the photoresponsive material layer. The diffractive waveplates are obtained when exposure time of photoresponsive material layer exceeds an order of magnitude the time period that is known to produce spatially homogeneous orientation of the anisotropic overlayer. |
FILED | Tuesday, October 08, 2013 |
APPL NO | 14/048557 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/32 (20130101) G02B 5/3083 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/20 (20130101) Original (OR) Class Holographic Processes or Apparatus G03H 2001/0439 (20130101) G03H 2260/51 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983585 | Ross et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Issac M. Ross (Monterey, California); Ronald J. Proulx (Waban, Massachusetts); Joseph M. Greenslade (Camarillo, California); Mark Karpenko (Salinas, California) |
ABSTRACT | The disclosure provides a method and apparatus for determination of a control policy for a rigid body system, where the rigid body system comprises a sensor and a plurality of actuators designed to maneuver the rigid body system and orient the sensor toward a plurality of defined vertices, such as geographic points on the earth surface. A processor receives input data describing an initial state of the rigid body system and further receives a plurality of candidate vertices for potential targeting by the sensor. The processor additionally receives an intrinsic value for each vertex, reflecting the relative desirability of respective vertices in the plurality of vertices. The processor determines an appropriate control policy based on the vertices, the intrinsic values, and the rigid body system through a formulation of the determination process as an optimization problem which actively considers various constraints during the optimization, such as maneuvering and observation constraints. |
FILED | Wednesday, February 08, 2017 |
APPL NO | 15/427858 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/286 (20130101) B64G 1/1021 (20130101) B64G 2001/245 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0094 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 7/185 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983919 | Ly |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Paul Ly (Alhambra, California) |
ABSTRACT | An apparatus and method for testing and troubleshooting systems, such as remote systems, have been developed that provide for a test control system configured to perform testing on a system under test. The test control system may include an electronic device operable to display a system fault code failure matrix visualization that may include fault codes and/or fault locations for one or more subsystems of a SUT. The test control system may also include an aggregated subsystem fault locations database that stores previously identified system or subsystem fault locations of the SUT that may lead to a source of an issue causing a particular fault code for the SUT, where the electronic device is operable to access the aggregated subsystem fault locations database to obtain the various previously identified fault locations. The previously identified system or subsystem fault locations may be based on previous testing of a system or subsystem. |
FILED | Friday, March 18, 2016 |
APPL NO | 15/074517 |
ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 11/079 (20130101) Original (OR) Class G06F 11/0739 (20130101) G06F 11/0769 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984109 | da Silva et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Gabriela Jacques da Silva (Brooklyn, New York); Kun-Lung Wu (Yorktown Heights, New York); Mindi Yuan (Urbana, Illinois) |
ABSTRACT | A system to manage clustering vertices of a streaming graph includes a memory storing a computer program, a vertex structure storing vertices of the graph, and a cluster structure storing clusters of the graph, and a processor. Each cluster structure comprises a plurality of edge structures represent edges of the graph and each edge structure comprises two of the vertices. The processor is configured to execute the program to cluster the vertices using the structures and a maximum cluster size that is constant. |
FILED | Wednesday, March 19, 2014 |
APPL NO | 14/219373 |
ART UNIT | 2155 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 17/30353 (20130101) Original (OR) Class G06F 17/30598 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984143 | Luo et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Gang Luo (Salt Lake City, Utah); Chunqiang Tang (Ossining, New York); Philip Shi-lung Yu (Chappaqua, New York) |
ABSTRACT | There are provided a system and method for resource adaptive, real-time new event detection. The method includes capturing, from among documents in a document streaming environment that includes a plurality of remote streaming document sources, first-story documents. The method further includes storing any of the documents determined to be the first-story documents in a memory. The method also includes classifying the documents as important or non-important based on pre-specified criteria. The method additionally includes storing, in the memory, only information of the documents classified as important, when the memory overflows. The method further includes discarding the documents that are classified as non-important when a document consumption rate from the memory is less than a document insertion rate into the memory. The method additionally includes removing the information of the documents classified as important from the memory subsequent to one of consumption and processing by a consumer. |
FILED | Wednesday, March 25, 2015 |
APPL NO | 14/668561 |
ART UNIT | 2178 — Graphical User Interface and Document Processing |
CURRENT CPC | Electric Digital Data Processing G06F 17/30011 (20130101) G06F 17/30117 (20130101) G06F 17/30312 (20130101) G06F 17/30516 (20130101) G06F 17/30598 (20130101) Original (OR) Class G06F 17/30684 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984147 | Long et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
ASSIGNEE(S) | The Research Foundation for the State University of New York (Binghamton, New York) |
INVENTOR(S) | Bo Long (Palo Alto, California); Zhongfei Mark Zhang (Vestal, New York) |
ABSTRACT | Relational clustering has attracted more and more attention due to its phenomenal impact in various important applications which involve multi-type interrelated data objects, such as Web mining, search marketing, bioinformatics, citation analysis, and epidemiology. A probabilistic model is presented for relational clustering, which also provides a principal framework to unify various important clustering tasks including traditional attributes-based clustering, semi-supervised clustering, co-clustering and graph clustering. The model seeks to identify cluster structures for each type of data objects and interaction patterns between different types of objects. Under this model, parametric hard and soft relational clustering algorithms are provided under a large number of exponential family distributions. The algorithms are applicable to relational data of various structures and at the same time unify a number of state-of-the-art clustering algorithms: co-clustering algorithms, the k-partite graph clustering, and semi-supervised clustering based on hidden Markov random fields. |
FILED | Friday, June 17, 2016 |
APPL NO | 15/186063 |
ART UNIT | 2167 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 17/30598 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 99/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984323 | Amir et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Arnon Amir (Saratoga, California); Pallab Datta (San Jose, California); Dharmendra S. Modha (San Jose, California); Benjamin G. Shaw (San Francisco, California) |
ABSTRACT | Embodiments of the invention provide a method comprising maintaining a library of one or more compositional prototypes. Each compositional prototype is associated with a neurosynaptic program. The method further comprises searching the library based on one or more search parameters. At least one compositional prototype satisfying the search parameters is selected. A neurosynaptic network is generated or extended by applying one or more rules associated with the selected compositional prototypes. |
FILED | Thursday, March 26, 2015 |
APPL NO | 14/669575 |
ART UNIT | 2122 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) Original (OR) Class G06N 3/082 (20130101) G06N 3/105 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984324 | Alvarez-Icaza et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Rodrigo Alvarez-Icaza (Mountain View, California); John V. Arthur (Mountain View, California); Andrew S. Cassidy (San Jose, California); Bryan L. Jackson (Fremont, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California); Jun Sawada (Austin, Texas) |
ABSTRACT | One embodiment provides a system comprising a memory device for maintaining deterministic neural data relating to a digital neuron and a logic circuit for deterministic neural computation and stochastic neural computation. Deterministic neural computation comprises processing a neuronal state of the neuron based on the deterministic neural data maintained. Stochastic neural computation comprises generating stochastic neural data relating to the neuron and processing the neuronal state of the neuron based on the stochastic neural data generated. |
FILED | Wednesday, November 16, 2016 |
APPL NO | 15/353675 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) Original (OR) Class G06N 3/0472 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984326 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Yang Chen (Westlake Village, California); Yongqiang Cao (Newton, Massachusetts); Deepak Khosla (Camarillo, California) |
ABSTRACT | Described is system for simulating spiking neural networks for image and video processing. The system processes an image with a spiking neural network simulator having a plurality of inter-connected modules. Each module comprises a plurality of neuron elements. Processing the image further comprises performing a neuron state update for each module, that includes aggregating input spikes and updating neuron membrane potentials, and performing spike propagation for each module, which includes transferring spikes generated in a current time step. Finally, an analysis result is output. |
FILED | Monday, April 06, 2015 |
APPL NO | 14/680057 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/62 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984438 | Saquib |
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FUNDED BY |
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APPLICANT(S) | Goodrich Corporation (Charlotte, North Carolina) |
ASSIGNEE(S) | Goodrich Corporation (Charlotte, North Carolina) |
INVENTOR(S) | Suhail S. Saquib (Shrewsbury, Massachusetts) |
ABSTRACT | A method of registering images includes identifying a block size for a warp estimation on a block by block basis to improve registration of a first image to a master image, and performing the warp estimation on a block by block basis to produce warp data, wherein the warp data includes a warp vector for each block and its associated uncertainty. The method also includes performing a warp model fit on the warp data to produce reduced noise warp data, and applying the reduced noise warp data to the first image for improved registration of the first image to the master image. |
FILED | Tuesday, February 09, 2016 |
APPL NO | 15/019790 |
ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Image Data Processing or Generation, in General G06T 3/0093 (20130101) Original (OR) Class G06T 5/002 (20130101) G06T 2207/10004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984671 | Ruffa |
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FUNDED BY |
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APPLICANT(S) | Anthony A Ruffa (Hope Valley, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Anthony A Ruffa (Hope Valley, Rhode Island) |
ABSTRACT | An acoustic projector is provided with an enclosure having a semi-permeable membrane on one side. High salinity liquid is injected at the enclosure to increase osmotic pressure. Valves thereafter allow free flooding between the enclosure and surrounding seawater to equalize the pressure. Transient pressure in the enclosure generates a pressure pulse that propagates from the semi-permeable membrane. The timing of the injection by salt jets and the free-flooding valves enables a repeatable acoustic pulse at low frequencies and a determinable upper frequency. If the acoustic projector is mounted to be conformal to the hull of a ship; the acoustic projector includes a free-flowing region on one side of a semi-permeable membrane and valves. When the valves are opened; the other side of the membrane is free-flooded. Salt jets inject high salinity liquid into an enclosure to increase pressure with the result of an acoustic pressure pulse. |
FILED | Monday, September 25, 2017 |
APPL NO | 15/713909 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0622 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 9/121 (20130101) G10K 11/008 (20130101) Original (OR) Class G10K 11/18 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984860 | Walton et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Scott G. Walton (Fairfax, Virginia); David R. Boris (Silver Spring, Maryland); Tzvetelina Petrova (Gaithersburg, Maryland); Eric D. Gillman (Arlington, Virginia) |
ABSTRACT | An apparatus and methods to increase and direct the spatial volume of atmospheric pressure plasma jets. One or more additional gas flows is introduced to intersect the plasma jet. As the plasma jet interacts with these additional gas flows, the direction of propagation of the plasma jet is altered, the plasma expands into the volume defined by the additional gas flow, and the volume and effective surface area of the plasma jet increases accordingly, while the power increase needed to drive the increase in plasma volume scales sub-linearly with the increase in volume. |
FILED | Friday, October 27, 2017 |
APPL NO | 15/795714 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/32449 (20130101) Original (OR) Class H01J 2237/327 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984943 | Warner et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Keith Warner (Whitinsville, Massachusetts); Richard P. D'Onofrio (Norton, Massachusetts); Donna-Ruth W. Yost (Acton, Massachusetts) |
ABSTRACT | In a system for aligning at least two semiconductor structures for coupling, an alignment device includes a mounting structure having at least first and second opposing portions. The alignment device also includes a first mounting portion movably coupled to the first portion of the mounting structure, the first mounting portion configured to couple to a first surface of a first semiconductor structure. The alignment device additionally includes a second mounting portion movably coupled to the second portion of the mounting structure, the second mounting portion configured to couple to a second surface of a second semiconductor structure. The alignment device further includes one or more imaging devices disposed above at least one of the first and second mounting portions of the alignment device, the imaging devices configured to capture and/or or detect alignment marks in at least the first semiconductor structure. A corresponding method for aligning two or more semiconductor structures for coupling is also provided. |
FILED | Thursday, December 22, 2016 |
APPL NO | 15/388625 |
ART UNIT | 2891 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/20 (20130101) Original (OR) Class H01L 24/75 (20130101) H01L 24/83 (20130101) H01L 27/0688 (20130101) H01L 2224/8313 (20130101) H01L 2224/75753 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985177 | Khan et al. |
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FUNDED BY |
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APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | M. Asif Khan (Irmo, South Carolina); Qhalid Fareed (Columbia, South Carolina); Vinod Adivarahan (Columbia, South Carolina) |
ABSTRACT | An ultraviolet light emitting semiconductor chip, its use in a LED, and methods of its fabrication are disclosed. The semiconductor chip can include a buffer layer of AlxGa1-xN, where 0<x≤1 having a thickness from about 10 μm to about 3 mm and defining apertures in the thickness of the buffer layer formed due to lateral overgrowth of the buffer layer over a grooved basal substrate. A n-junction LED layer overlying the buffer layer, a multiple quantum well LED layer overlying the n-junction LED layer, and a p-junction LED layer overlying the multiple quantum well LED layer are also included in the chip, where all of the LED layers comprise AlxGa1-xN, where 0<x≤1. |
FILED | Tuesday, March 22, 2016 |
APPL NO | 15/077138 |
ART UNIT | 2896 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0243 (20130101) H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/02458 (20130101) H01L 21/02647 (20130101) H01L 33/06 (20130101) H01L 33/007 (20130101) H01L 33/12 (20130101) Original (OR) Class H01L 33/20 (20130101) H01L 33/22 (20130101) H01L 33/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985193 | Dial et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Oliver Dial (Yorktown Heights, New York); Jay M. Gambetta (Yorktown Heights, New York); Douglas T. McClure, III (Rye, New York); Matthias Steffen (Cortlandt Manor, New York) |
ABSTRACT | A technique relates a superconducting microwave cavity. An array of posts has different heights in the cavity, and the array supports a localized microwave mode. The array of posts includes lower resonant frequency posts and higher resonant frequency posts. The higher resonant frequency posts are arranged around the lower resonant frequency posts. A first plate is opposite a second plate in the cavity. One end of the lower resonant frequency posts is positioned on the second plate so as to be electrically connected to the second plate. Another end of the lower resonant frequency posts in the array is open so as not to form an electrical connection to the first plate. Qubits are connected to the lower resonant frequency posts in the array of posts, such that each of the qubits is physically connected to one or two of the lower resonant frequency posts in the array of posts. |
FILED | Tuesday, June 30, 2015 |
APPL NO | 14/755181 |
ART UNIT | 2827 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985197 | Hutchison et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Geoffrey R. Hutchison (Pittsburgh, Pennsylvania); Xinfeng Quan (Pittsburgh, Pennsylvania) |
ABSTRACT | A piezoelectric material, comprising: a piezoelectric self-assembling monolayer of oligopeptides; a conductive surface; and a substrate, wherein the conductive surface is located between the piezoelectric self-assembling monolayer of oligopeptides and the substrate. A touch sensitive device, comprising: a first piezoelectric material, comprising: a piezoelectric self-assembling monolayer of oligopeptides containing a dipole moment; a conductive surface; and a substrate; a second piezoelectric material, comprising: a piezoelectric self-assembling monolayer of oligopeptides containing a dipole moment; a conductive surface; and a substrate, wherein the oligopeptides making up the self-assembling monolayer of the first and second piezoelectric materials, respectively, have the same amino acid sequence but have an equal and opposite dipole moment. |
FILED | Friday, December 06, 2013 |
APPL NO | 14/099783 |
ART UNIT | 1675 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/193 (20130101) Original (OR) Class H01L 41/317 (20130101) H01L 41/0805 (20130101) H01L 41/1132 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985460 | Georgakopoulos et al. |
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FUNDED BY |
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APPLICANT(S) | Stavros Georgakopoulos (Boca Raton, Florida); Kun Bao (Miami, Florida) |
ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
INVENTOR(S) | Stavros Georgakopoulos (Boca Raton, Florida); Kun Bao (Miami, Florida) |
ABSTRACT | Novel and advantageous systems and methods for wireless power transfer (WPT) via multiple-resonator conformal strongly coupledmagnetic resonance (CSCMR) are provided. Instead of using a single loop as a resonator, multiple resonators can be used. This leads to lower operating frequency (e.g., 30% decrease), extended WPT range (e.g., 20% increase), and higher WPT efficiency compared to single-resonator systems of the same size. |
FILED | Friday, July 17, 2015 |
APPL NO | 14/802794 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) Original (OR) Class H02J 50/12 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985934 | Salo |
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FUNDED BY |
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APPLICANT(S) | Timothy J. Salo (Saint Paul, Minnesota) |
ASSIGNEE(S) | |
INVENTOR(S) | Timothy J. Salo (Saint Paul, Minnesota) |
ABSTRACT | A method and apparatus where network-layer devices use host-provided, detailed, per-packet, semantic information (DPPS information), which describes the content, meaning, importance, and/or other attributes of particular application data and is associated with each packet, to provide enhanced network services. In some embodiments of the above method, network-layer devices use DPPS information that includes QoS-related information to provide fine-grained, content-aware, and/or complex QoS assurances or similar services. In some embodiments, network-layer devices use DPPS information to provide network-based, application-protocol-independent, rate-adaptation services. In some embodiments, network-layer devices use DPPS information to provide highly efficient, application-protocol-independent, publish/subscribe dissemination services. |
FILED | Tuesday, May 10, 2016 |
APPL NO | 15/151378 |
ART UNIT | 2458 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/14 (20130101) H04L 45/306 (20130101) H04L 45/308 (20130101) H04L 47/24 (20130101) H04L 47/32 (20130101) H04L 47/805 (20130101) H04L 47/806 (20130101) H04L 47/2441 (20130101) H04L 63/06 (20130101) H04L 63/0428 (20130101) Original (OR) Class H04L 67/32 (20130101) H04L 67/327 (20130101) H04L 67/2804 (20130101) H04L 69/22 (20130101) H04L 69/321 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09986162 | Pixton et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
INVENTOR(S) | Bruce M. Pixton (Woodbridge, Virginia); Jay N. Vizgaitis (Alexandria, Virginia) |
ABSTRACT | An optical system that images a scene at two different fields of view, with switching between fields of view enabled by switchable mirrored surface is disclosed. A voltage change across the switchable mirror element generates a change in the reflection and transmission properties of the element, such that the element switches between a mirror state and a lens state. When nested in an annular reflective optic system of a given field of view, the switching element enables the opening of an additional optical path through the center of the reflective optics where a set of refractive optics are assembled into an imaging system for a second field of view. This dual field-of-view system changes field of view with no mechanical movement. |
FILED | Thursday, October 19, 2017 |
APPL NO | 15/787744 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 17/0657 (20130101) G02B 27/0006 (20130101) G02B 27/0081 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/163 (20130101) G02F 1/13306 (20130101) Pictorial Communication, e.g Television H04N 5/2254 (20130101) H04N 5/23238 (20130101) H04N 5/23245 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09986662 | Chainer et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); Pritish R. Parida (Stamford, Connecticut); Joel A. Silberman (Somers, New York) |
ABSTRACT | A cooling system includes a device to be cooled and a cooling device integrated with the device to be cooled. A cooling volume has cavities and active coolant flow controls configured to adjust coolant flow through the cavities. A reservoir is in fluid communication with the cavities and has a liquid outlet and an inlet for a gas or gas-liquid mixture. A two-phase coolant is in the reservoir and cavities. The two-phase coolant has a phase transition temperature between an ambient temperature and an expected device temperature. A capacitance sensor is configured to determine a coolant capacitance in the cavities. A control module is configured to determine a vapor quality and void fraction of the coolant based on the measured capacitance and to increase coolant flow if the determined vapor quality and void fraction indicate a dry-out condition. A secondary cooling line removes heat from the cooling device. |
FILED | Tuesday, June 06, 2017 |
APPL NO | 15/614936 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/06 (20130101) F28D 15/025 (20130101) F28D 15/0266 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20327 (20130101) H05K 7/20336 (20130101) H05K 7/20381 (20130101) Original (OR) Class H05K 7/20809 (20130101) H05K 7/20827 (20130101) H05K 7/20836 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09986663 | Broido et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | David A. Broido (Needham, Massachusetts); Thomas L. Reinecke (Alexandria, Virginia); Lucas R. Lindsay (Alexandria, Virginia) |
ABSTRACT | High thermal conductivity materials and methods of their use for thermal management applications are provided. In some embodiments, a device comprises a heat generating unit (304) and a thermally conductive unit (306, 308, 310) in thermal communication with the heat generating unit (304) for conducting heat generated by the heat generating unit (304) away from the heat generating unit (304), the thermally conductive unit (306, 308, 310) comprising a thermally conductive compound, alloy or composite thereof. The thermally conductive compound may include Boron Arsenide, Boron Antimonide, Germanium Carbide and Beryllium Selenide. |
FILED | Wednesday, January 29, 2014 |
APPL NO | 14/763993 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Couplings for Transmitting Rotation; Clutches; Brakes F16D 69/00 (20130101) F16D 69/02 (20130101) F16D 2066/001 (20130101) F16D 2200/0047 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3731 (20130101) H01L 23/3738 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20481 (20130101) Original (OR) Class H05K 7/20509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 09981313 | Cappillino et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Patrick J. Cappillino (Fremont, California); David B. Robinson (Hayward, California) |
ABSTRACT | A method including encapsulating or capping metallic nanoparticles by a dendrimer or a polymer with binding sites for metal particless or metal ions dispersed in a fluid; modifying the fluid to disrupt the interaction of the dendrimer or polymer with the particles; and subsequently or concomitantly sintering or partially consolidating the zero valent metal. A method including introducing a first metal salt and a second metal salt into a dendrimer or a polymer with binding sites for metals or metal ions; reducing a metal ion of the first metal salt to a zero valent first metal and a metal ion of the second metal salt to a zero valend second metal; disrupting an interaction between the dendrimer or the polymer and the first metal and the second metal; and sintering or partially consolidating the first metal and the second metal. |
FILED | Friday, June 14, 2013 |
APPL NO | 13/917762 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 5/10 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981315 | Rieken et al. |
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FUNDED BY |
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APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Joel R. Rieken (Nevada, Iowa); Andrew J. Heidloff (West Des Moines, Iowa); Iver E. Anderson (Ames, Iowa) |
ABSTRACT | A concentric ring gas atomization nozzle with isolated gas supply manifolds is provided for manipulating the close-coupled atomization gas structure to improve the yield of atomized powders. |
FILED | Wednesday, September 24, 2014 |
APPL NO | 14/121613 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 9/082 (20130101) Original (OR) Class B22F 2009/0892 (20130101) Alloys C22C 32/0026 (20130101) C22C 38/002 (20130101) C22C 38/005 (20130101) C22C 38/06 (20130101) C22C 38/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981338 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Xun Liu (Ann Arbor, Michigan); Shuhuai Lan (Ann Arbor, Michigan); Jun Ni (Ann Arbor, Michigan) |
ABSTRACT | A hybrid Friction Stir Welding approach and device for dissimilar materials joining employing Electro-Plastic Effect. The approach and device include an introduction of high density, short period current pulses into traditional friction stir welding process, which therefore can generate a localized softened zone in the workpiece during plastic stirring without significant additional temperature increase. This material softened zone is created by high density current pulses based on Electro-Plastic Effect and will move along with the friction stir welding tool. Smaller downward force, larger processing window and better joint quality for dissimilar materials are expected to be achieved through this hybrid welding technique. |
FILED | Thursday, June 18, 2015 |
APPL NO | 14/742749 |
ART UNIT | 3742 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/126 (20130101) B23K 20/1245 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981377 | Morin et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Stephen A. Morin (Arlington, Massachusetts); Robert F. Shepherd (Brooktondale, New York); Adam Stokes (Watertown, Massachusetts); Filip Ilievski (Santa Clara, California); Ramses V. Martinez (Somerville, Massachusetts); Jamie L. Branch (Topeka, Kansas); Carina R. Fish (Cambridge, Massachusetts); Lihua Jin (Somerville, Massachusetts); Rui M. D. Nunes (Somerville, Massachusetts); Zhigang Suo (Lexington, Massachusetts); George M. Whitesides (Newton, Massachusetts) |
ABSTRACT | Systems and methods for providing flexible robotic actuators are disclosed. Some embodiments of the disclosed subject matter include a soft robot capable of providing a radial deflection motions; a soft tentacle actuator capable of providing a variety of motions and providing transportation means for various types of materials; and a hybrid robotic system that retains desirable characteristics of both soft robots and hard robots. Some embodiments of the disclosed subject matter also include methods for operating the disclosed robotic systems. |
FILED | Monday, September 08, 2014 |
APPL NO | 14/480106 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Domestic Washing or Cleaning; Suction Cleaners in General A47L 9/2836 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) Original (OR) Class B25J 9/1075 (20130101) B25J 9/1697 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/22 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/20305 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981438 | Monaghan et al. |
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FUNDED BY |
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APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Philip Harold Monaghan (Hockessin, Delaware); John McConnell Delvaux (Fountain Inn, South Carolina); Glenn Curtis Taxacher (Simpsonville, South Carolina) |
ABSTRACT | A pre-form CMC cavity and method of forming pre-form CMC cavity for a ceramic matrix component includes providing a mandrel, applying a base ply to the mandrel, laying-up at least one CMC ply on the base ply, removing the mandrel, and densifying the base ply and the at least one CMC ply. The remaining densified base ply and at least one CMC ply form a ceramic matrix component having a desired geometry and a cavity formed therein. Also provided is a method of forming a CMC component. |
FILED | Tuesday, June 09, 2015 |
APPL NO | 14/734028 |
ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/0028 (20130101) Original (OR) Class Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/282 (20130101) F01D 5/284 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4998 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981758 | Judd et al. |
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FUNDED BY |
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APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Stephen Judd (Los Alamos, New Mexico); Nicholas Dallmann (Los Alamos, New Mexico); Kevin McCabe (Santa Fe, New Mexico); Adam Warniment (Santa Fe, New Mexico) |
ABSTRACT | An adaptable, modular, multi-purpose (AMM) space vehicle backplane may accommodate boards and components for various missions. The AMM backplane may provide a common hardware interface and common board-to-board communications. Components, connectors, test points, and sensors may be embedded directly into the backplane to provide additional functionality, diagnostics, and system access. Other space vehicle sections may plug directly into the backplane. |
FILED | Monday, June 22, 2015 |
APPL NO | 14/745810 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/10 (20130101) B64G 1/66 (20130101) B64G 1/428 (20130101) Original (OR) Class B64G 2001/1092 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/14 (20130101) H05K 7/1439 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981893 | Boyle |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Timothy J. Boyle (Albuquerque, New Mexico) |
ABSTRACT | Lanthanide fluorinated alkoxide derivatives can be synthesized from the alcoholysis reaction of the lanthanide bis-trimethylsilyl amide and an excess amount of hexafluoro iso-propanol. Nanoparticles can be formed from the lanthanide fluorinated alkoxide derivatives by a solvothermal or solution precipitation process. |
FILED | Friday, January 29, 2016 |
APPL NO | 15/010899 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/0062 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Acyclic or Carbocyclic Compounds C07C 29/00 (20130101) C07C 29/70 (20130101) Original (OR) Class C07C 29/70 (20130101) C07C 31/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982068 | Gavvalapalli et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Nagarjuna Gavvalapalli (Urbana, Illinois); Jeffrey S. Moore (Savoy, Illinois); Joaquin Rodriguez-Lopez (Urbana, Illinois); Kevin Cheng (Urbana, Illinois); Mei Shen (Urbana, Illinois); Timothy Lichtenstein (Carol Stream, Illinois) |
ABSTRACT | The invention provides a redox flow battery comprising a microporous or nanoporous size-exclusion membrane, wherein one cell of the battery contains a redox-active polymer dissolved in the non-aqueous solvent or a redox-active colloidal particle dispersed in the non-aqueous solvent. The redox flow battery provides enhanced ionic conductivity across the electrolyte separator and reduced redox-active species crossover, thereby improving the performance and enabling widespread utilization. Redox active poly(vinylbenzyl ethylviologen) (RAPs) and redox active colloidal particles (RACs) were prepared and were found to be highly effective redox species. Controlled potential bulk electrolysis indicates that 94-99% of the nominal charge on different RAPs is accessible and the electrolysis products are stable upon cycling. The high concentration attainable (>2.0 M) for RAPs in common non-aqueous battery solvents, their electrochemical and chemical reversibility, and their hindered transport across porous separators make them attractive materials for non-aqueous redox flow batteries based on size-selectivity. |
FILED | Tuesday, January 19, 2016 |
APPL NO | 15/000910 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 8/30 (20130101) C08F 12/18 (20130101) C08F 12/26 (20130101) C08F 12/32 (20130101) C08F 112/14 (20130101) Original (OR) Class C08F 112/14 (20130101) C08F 212/14 (20130101) C08F 212/14 (20130101) C08F 212/14 (20130101) C08F 212/36 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/02 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) H01M 2300/0025 (20130101) H01M 2300/0028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982332 | Seals |
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FUNDED BY |
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APPLICANT(S) | Roland D. Seals (Oak Ridge, Tennessee) |
ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Roland D. Seals (Oak Ridge, Tennessee) |
ABSTRACT | The present disclosure relates generally to hardface coating systems and methods for metal alloys and other materials for wear and corrosion resistant applications. More specifically, the present disclosure relates to hardface coatings that include a network of titanium monoboride (TiB) needles or whiskers in a matrix, which are formed from titanium (Ti) and titanium diboride (TiB2) precursors by reactions enabled by the inherent energy provided by the process heat associated with coating deposition and, optionally, coating post-heat treatment. These hardface coatings are pyrophoric, thereby generating further reaction energy internally, and may be applied in a functionally graded manner. The hardface coatings may be deposited in the presence of a number of fluxing agents, beta stabilizers, densification aids, diffusional aids, and multimode particle size distributions to further enhance their performance characteristics. |
FILED | Monday, July 13, 2015 |
APPL NO | 14/797344 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 35/34 (20130101) B23K 35/325 (20130101) B23K 35/327 (20130101) Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/10 (20130101) Original (OR) Class C23C 4/067 (20160101) C23C 4/134 (20160101) C23C 10/30 (20130101) C23C 12/02 (20130101) C23C 16/38 (20130101) C23C 18/08 (20130101) C23C 18/1204 (20130101) C23C 18/1241 (20130101) C23C 18/1275 (20130101) C23C 24/085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982523 | Ciezobka et al. |
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FUNDED BY |
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APPLICANT(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
ASSIGNEE(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
INVENTOR(S) | Jordan Ciezobka (Addison, Illinois); Debotyam Maity (Des Plaines, Illinois) |
ABSTRACT | A hydraulic fracturing system and method for enhancing effective permeability of earth formations to increase hydrocarbon production, enhance operation efficiency by reducing fluid entry friction due to tortuosity and perforation, and to open perforations that are either unopened or not effective using traditional techniques, by varying a pump rate and/or a flow rate to a wellbore. |
FILED | Tuesday, March 21, 2017 |
APPL NO | 15/464939 |
ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/26 (20130101) Original (OR) Class E21B 49/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982540 | Weaver |
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FUNDED BY |
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APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
INVENTOR(S) | Adam M. Weaver (Lafayette, Indiana) |
ABSTRACT | An apparatus and method for passing fluid flow through at least a portion of a blade of turbomachinery, such as a gas turbine or the like. The fluid flow is directed through a plurality of flow channels which are interwoven with each other. Each flow channel is non-intersecting with any other flow channel and thus does not contact fluid flowing within any other flow channel. The method and apparatus can be used to reduce heat transfer and thus reduce thermal stresses, particularly in the blade. |
FILED | Friday, September 13, 2013 |
APPL NO | 14/426910 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) F01D 5/187 (20130101) Original (OR) Class F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/183 (20130101) F05D 2250/314 (20130101) F05D 2250/611 (20130101) F05D 2260/2214 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 2900/03043 (20130101) F23R 2900/03045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982663 | Liu |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
INVENTOR(S) | Shaorong Liu (Norman, Oklahoma) |
ABSTRACT | An electroosmotic pump unit includes at least a first pump element, at least a second pump element, and an electrode. Each pump element includes a tube, an electrically grounded fluid inlet, a fluid outlet electrically coupled to the electrode, and a porous monolith immobilized in the tube and having open pores having net surface charges. When the electrode applies a voltage across the monoliths, a fluid supplied to the first pump element flows through the pump elements in a direction from a fluid inlet of the first pump element toward a fluid outlet of the second pump element. A plurality of electroosmotic pump units may be connected in series in a pump assembly. The electroosmotic pump unit, or pump assembly, may be connected to an apparatus such as a HPLC. |
FILED | Friday, October 10, 2014 |
APPL NO | 14/511860 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Separation B01D 61/427 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 19/04 (20130101) F04B 19/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982893 | Rodriguez et al. |
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FUNDED BY |
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APPLICANT(S) | Siemens Energy, Inc. (Orlando, Florida) |
ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
INVENTOR(S) | Jose L. Rodriguez (Lake Mary, Florida); Matthew J. Golsen (Deltona, Florida) |
ABSTRACT | A combustor assembly (17) including guide vanes (44) located between an inner cylinder (24) and a flow sleeve (25). Each guide vane (44) includes a circumferentially angled flow directing portion (60) adjacent to a leading edge (46). The leading edge (46) of at least one guide vane (44) can be located radially inward along the longitudinal axis (54) relative to the leading edge (46) of at least one other of the guide vanes (44). The length of the guide vanes (44) may vary, and the circumferential spacing between a first pair of the guide vanes (44) can be different from a spacing between a second pair of the guide vanes (44). |
FILED | Friday, September 05, 2014 |
APPL NO | 15/506055 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/04 (20130101) F23R 3/54 (20130101) F23R 3/425 (20130101) Original (OR) Class F23R 2900/03043 (20130101) F23R 2900/03045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982920 | Feng et al. |
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FUNDED BY |
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APPLICANT(S) | Carrier Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | CARRIER CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Yinshan Feng (South Windsor, Connecticut); Jinliang Wang (Ellington, Connecticut); Futao Zhao (Farmington, Connecticut); Parmesh Verma (South Windsor, Connecticut); Thomas D. Radcliff (Vernon, Connecticut) |
ABSTRACT | A method of operating a heat transfer system includes starting operation of a first heat transfer fluid vapor/compression circulation loop including a fluid pumping mechanism, a heat exchanger for rejecting thermal energy from a first heat transfer fluid, and a heat absorption side of an internal heat exchanger. A first conduit in a closed fluid circulation loop circulates the first heat transfer fluid therethrough. Operation of a second two-phase heat transfer fluid circulation loop is started after starting operation of the first heat transfer fluid circulation loop. The second heat transfer fluid circulation loop transfers heat to the first heat transfer fluid circulation loop through the internal heat exchanger and includes a heat rejection side of the internal heat exchanger, a liquid pump, and a heat exchanger evaporator. A second conduit in a closed fluid circulation loop circulates a second heat transfer fluid therethrough. |
FILED | Thursday, August 14, 2014 |
APPL NO | 15/029824 |
ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 7/00 (20130101) Original (OR) Class F25B 9/008 (20130101) F25B 23/006 (20130101) F25B 25/005 (20130101) F25B 41/00 (20130101) F25B 2500/26 (20130101) F25B 2500/27 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983066 | Armstrong et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Michael Robert Armstrong (Livermore, California); Harry B. Radousky (San Leandro, California); Joseph Zaug (Livermore, California) |
ABSTRACT | A system for high sensitivity, high time resolution detection of an arbitrary spontaneous emission is disclosed. The system may use a local oscillator (LO) for generating an LO input optical signal, and an linear optical mixer for receiving and mixing the input optical signal and an arbitrary spontaneous emission. The 2D detector generates a first component output and a second component. A subsystem receives the component outputs and produces first and second dispersed spectrum output signals. At least a first ultra-high speed camera is used for imaging one of the first or second dispersed spectrum output signals. |
FILED | Wednesday, September 06, 2017 |
APPL NO | 15/696704 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0218 (20130101) G01J 3/2803 (20130101) G01J 9/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983124 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon State University (Corvallis, Oregon); U.S. Department of Energy (Washington, District of Columbia) |
ASSIGNEE(S) | Oregon State University (Corvallis, Oregon); U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Alan X. Wang (Corvallis, Oregon); Chih-hung Chang (Corvallis, Oregon); Ki-Joong Kim (Corvallis, Oregon); Xinyuan Chong (Corvallis, Oregon); Paul R. Ohodnicki (Allison Park, Pennsylvania) |
ABSTRACT | Disclosed herein are embodiments of sensor devices comprising a sensing component able to determine the presence of, detect, and/or quantify detectable species in a variety of environments and applications. The sensing components disclosed herein can comprise MOF materials, plasmonic nanomaterials, or combinations thereof. In an exemplary embodiment, light guides can be coupled with the sensing components described herein to provide sensor devices capable of increased NIR detection sensitivity in determining the presence of detectable species, such as gases and volatile organic compounds. In another exemplary embodiment, optical properties of the plasmonic nanomaterials combined with MOF materials can be monitored directly to detect analyte species through their impact on external conditions surrounding the particle or as a result of charge transfer to and from the plasmonic material as a result of interactions with the plasmonic material and/or the MOF material. |
FILED | Tuesday, February 09, 2016 |
APPL NO | 15/019811 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/226 (20130101) B01J 20/28007 (20130101) B01J 20/28097 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 21/554 (20130101) G01N 21/3504 (20130101) Original (OR) Class G01N 21/7703 (20130101) G01N 2021/7709 (20130101) G01N 2021/7763 (20130101) G01N 2201/088 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1226 (20130101) G02B 2006/12138 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983151 | Barty |
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FUNDED BY |
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APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Christopher P. J. Barty (Hayward, California) |
ABSTRACT | Ultralow-dose, x-ray or gamma-ray imaging is based on fast, electronic control of the output of a laser-Compton x-ray or gamma-ray source (LCXS or LCGS). X-ray or gamma-ray shadowgraphs are constructed one (or a few) pixel(s) at a time by monitoring the LCXS or LCGS beam energy required at each pixel of the object to achieve a threshold level of detectability at the detector. An example provides that once the threshold for detection is reached, an electronic or optical signal is sent to the LCXS/LCGS that enables a fast optical switch that diverts, either in space or time the laser pulses used to create Compton photons. In this way, one prevents the object from being exposed to any further Compton x-rays or gamma-rays until either the laser-Compton beam or the object are moved so that a new pixel location may be illumination. |
FILED | Thursday, May 07, 2015 |
APPL NO | 15/320047 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 9/24 (20130101) G01N 23/04 (20130101) Original (OR) Class X-ray Technique H05G 2/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983652 | Piga et al. |
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FUNDED BY |
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APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
ASSIGNEE(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
INVENTOR(S) | Leonardo Piga (Austin, Texas); Indrani Paul (Round Rock, Texas); Wei Huang (Frisco, Texas) |
ABSTRACT | Systems, apparatuses, and methods for balancing computation and communication power in power constrained environments. A data processing cluster with a plurality of compute nodes may perform parallel processing of a workload in a power constrained environment. Nodes that finish tasks early may be power-gated based on one or more conditions. In some scenarios, a node may predict a wait duration and go into a reduced power consumption state if the wait duration is predicted to be greater than a threshold. The power saved by power-gating one or more nodes may be reassigned for use by other nodes. A cluster agent may be configured to reassign the unused power to the active nodes to expedite workload processing. |
FILED | Friday, December 04, 2015 |
APPL NO | 14/959669 |
ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/3203 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985159 | Young et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | David L. Young (Golden, Colorado); Pauls Stradins (Golden, Colorado); William Nemeth (Littleton, Colorado) |
ABSTRACT | Methods for forming passivated contacts include implanting compound-forming ions into a substrate to about a first depth below a surface of the substrate, and implanting dopant ions into the substrate to about a second depth below the surface. The second depth may be shallower than the first depth. The methods also include annealing the substrate. |
FILED | Friday, November 11, 2016 |
APPL NO | 15/349630 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/028 (20130101) H01L 31/061 (20130101) Original (OR) Class H01L 31/0288 (20130101) H01L 31/0682 (20130101) H01L 31/0687 (20130101) H01L 31/1804 (20130101) H01L 31/1864 (20130101) H01L 31/02168 (20130101) H01L 31/02363 (20130101) H01L 31/022425 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985292 | Pratt et al. |
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FUNDED BY |
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APPLICANT(S) | Seeo, Inc (Hayward, California) |
ASSIGNEE(S) | Seeo, Inc. (Hayward, California) |
INVENTOR(S) | Russell Clayton Pratt (Foster City, California); Scott Allen Mullin (San Leandro, California); Hany Basam Eitouni (Oakland, California) |
ABSTRACT | A class of polymeric phosphorous esters can be used as binders for battery cathodes. Metal salts can be added to the polymers to provide ionic conductivity. The polymeric phosphorous esters can be formulated with other polymers either as mixtures or as copolymers to provide additional desirable properties. Examples of such properties include even higher ionic conductivity and improved mechanical properties. Furthermore, cathodes that include the polymeric phosphorous esters can be assembled with a polymeric electrolyte separator and an anode to form a complete battery. |
FILED | Monday, November 25, 2013 |
APPL NO | 14/089617 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/131 (20130101) H01M 4/136 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/622 (20130101) Original (OR) Class H01M 2300/0082 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985293 | Cui et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Yi Cui (Stanford, California); Kai Yan (Santa Clara, California); Steven Chu (Menlo Park, California) |
ABSTRACT | A battery includes 1) an anode, 2) a cathode, and 3) an electrolyte disposed between the anode and the cathode. The anode includes a current collector and an interfacial layer disposed over the current collector, and the interfacial layer includes an array of interconnected, protruding regions that define spaces. |
FILED | Thursday, February 02, 2017 |
APPL NO | 15/423376 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1673 (20130101) H01M 4/382 (20130101) H01M 4/628 (20130101) Original (OR) Class H01M 4/661 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985318 | Zhu et al. |
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FUNDED BY |
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APPLICANT(S) | Wildcat Discovery Technologies, Inc. (San Diego, California) |
ASSIGNEE(S) | WILDCAT DISCOVERY TECHNOLOGIES, INC (San Diego, California) |
INVENTOR(S) | Ye Zhu (San Diego, California); Deidre Strand (San Diego, California); Gang Cheng (San Diego, California) |
ABSTRACT | An electrochemical cell including a silicon-based anode and an electrolyte, where the electrolyte is formulated to contain solvents having cyclic sulfone or cyclic sulfite chemical structure. Specific additional solvent and salt combinations yield superior performance in these electrochemical cells. |
FILED | Tuesday, June 21, 2016 |
APPL NO | 15/188905 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2300/0028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985483 | Ouyang et al. |
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FUNDED BY |
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APPLICANT(S) | ABB Technology AG (Zurich, Switzerland) |
ASSIGNEE(S) | ABB Schweiz AG (Baden, Switzerland) |
INVENTOR(S) | Wen Ouyang (Apex, North Carolina); Varagur Ramanan (Cary, North Carolina) |
ABSTRACT | One embodiment is a unique Vernier machine comprising a rotor and a stator. The rotor comprises a back portion and a plurality of permanent magnets. The stator comprises a plurality of ferromagnetic arm structures, a plurality of ferromagnetic pole structures extending from each of the ferromagnetic arm structures in a direction toward the permanent magnets, and a plurality of conductive windings disposed about respective ones of the plurality of ferromagnetic arm structures. The ferromagnetic pole structures are structured to collect magnetic flux from the permanent magnets. The ferromagnetic pole structures of each of said ferromagnetic arm structures are spaced apart from one another according to a non-uniform pattern such that the ferromagnetic pole structures of a given ferromagnetic arm structure have substantially the same angular position relative to the permanent magnets radially opposite from the ferromagnetic pole structures of the given ferromagnetic arm structure. |
FILED | Tuesday, May 24, 2016 |
APPL NO | 15/163364 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Dynamo-electric Machines H02K 1/146 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985554 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Zhong Lin Wang (Merietta, Georgia); Guang Zhu (Atlanta, Georgia); Sihong Wang (Atlanta, Georgia); Long Lin (Atlanta, Georgia) |
ABSTRACT | A generator includes a first member, a second member and a sliding mechanism. The first member includes a first electrode and a first dielectric layer affixed to the first electrode. The first dielectric layer includes a first material that has a first rating on a triboelectric series. The second member includes a second material that has a second rating on the triboelectric series that is different from the first rating. The second member includes a second electrode. The second member is disposed adjacent to the first dielectric layer so that the first dielectric layer is disposed between the first electrode and the second electrode. The sliding mechanism is configured to cause relative lateral movement between the first member and the second member, thereby generating an electric potential imbalance between the first electrode and the second electrode. |
FILED | Tuesday, February 25, 2014 |
APPL NO | 14/189656 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985792 | Hamlet |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Jason Hamlet (Albuquerque, New Mexico) |
ABSTRACT | The various technologies presented herein relate to binding data (e.g., software) to hardware, wherein the hardware is to utilize the data. The generated binding can be utilized to detect whether at least one of the hardware or the data has been modified between an initial moment (enrollment) and a later moment (authentication). During enrollment, an enrollment value is generated that includes a signature of the data, a first response from a PUF located on the hardware, and a code word. During authentication, a second response from the PUF is utilized to authenticate any of the content in the enrollment value, and based upon the authentication, a determination can be made regarding whether the hardware and/or the data have been modified. If modification is detected then a mitigating operation can be performed, e.g., the hardware is prevented from utilizing the data. If no modification is detected, the data can be utilized. |
FILED | Tuesday, March 22, 2016 |
APPL NO | 15/077590 |
ART UNIT | 2497 — Cryptography and Security |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) H04L 9/3278 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985984 | Chavez et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Adrian R. Chavez (Albuquerque, New Mexico); William M. S. Stout (Albuquerque, New Mexico); Jason R. Hamlet (Albuquerque, New Mexico); Erik James Lee (Jackson, Missouri); Mitchell Tyler Martin (Albuquerque, New Mexico) |
ABSTRACT | The various technologies presented herein relate to determining a network attack is taking place, and further to adjust one or more network parameters such that the network becomes dynamically configured. A plurality of machine learning algorithms are configured to recognize an active attack pattern. Notification of the attack can be generated, and knowledge gained from the detected attack pattern can be utilized to improve the knowledge of the algorithms to detect a subsequent attack vector(s). Further, network settings and application communications can be dynamically randomized, wherein artificial diversity converts control systems into moving targets that help mitigate the early reconnaissance stages of an attack. An attack(s) based upon a known static address(es) of a critical infrastructure network device(s) can be mitigated by the dynamic randomization. Network parameters that can be randomized include IP addresses, application port numbers, paths data packets navigate through the network, application randomization, etc. |
FILED | Monday, October 26, 2015 |
APPL NO | 14/923049 |
ART UNIT | 2494 — Cryptography and Security |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/05 (20130101) G05B 2219/1105 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 61/2503 (20130101) H04L 63/1425 (20130101) H04L 63/1441 (20130101) Original (OR) Class H04L 67/10 (20130101) H04L 67/327 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09986627 | Barty |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Christopher P. J. Barty (Hayward, California) |
ABSTRACT | A method of x-ray and gamma-ray generation via laser Compton scattering uses the interaction of a specially-formatted, highly modulated, long duration, laser pulse with a high-frequency train of high-brightness electron bunches to both create narrow bandwidth x-ray and gamma-ray sources and significantly increase the laser to Compton photon conversion efficiency. |
FILED | Tuesday, June 27, 2017 |
APPL NO | 15/635119 |
ART UNIT | 2884 — Optics |
CURRENT CPC | X-ray Technique H05G 2/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09986663 | Broido et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | David A. Broido (Needham, Massachusetts); Thomas L. Reinecke (Alexandria, Virginia); Lucas R. Lindsay (Alexandria, Virginia) |
ABSTRACT | High thermal conductivity materials and methods of their use for thermal management applications are provided. In some embodiments, a device comprises a heat generating unit (304) and a thermally conductive unit (306, 308, 310) in thermal communication with the heat generating unit (304) for conducting heat generated by the heat generating unit (304) away from the heat generating unit (304), the thermally conductive unit (306, 308, 310) comprising a thermally conductive compound, alloy or composite thereof. The thermally conductive compound may include Boron Arsenide, Boron Antimonide, Germanium Carbide and Beryllium Selenide. |
FILED | Wednesday, January 29, 2014 |
APPL NO | 14/763993 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Couplings for Transmitting Rotation; Clutches; Brakes F16D 69/00 (20130101) F16D 69/02 (20130101) F16D 2066/001 (20130101) F16D 2200/0047 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3731 (20130101) H01L 23/3738 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20481 (20130101) Original (OR) Class H05K 7/20509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 09980668 | Strano et al. |
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FUNDED BY |
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APPLICANT(S) | Michael S. Strano (Lexington, Massachusetts); Paul W. Barone (Jamaica Plain, Massachusetts); Jin-Ho Ahn (Cambridge, Massachusetts); Kyungsuk Yum (Cambridge, Massachusetts); Thomas P. McNicholas (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Michael S. Strano (Lexington, Massachusetts); Paul W. Barone (Jamaica Plain, Massachusetts); Jin-Ho Ahn (Cambridge, Massachusetts); Kyungsuk Yum (Cambridge, Massachusetts); Thomas P. McNicholas (Cambridge, Massachusetts) |
ABSTRACT | A composition for sensing an analyte can include a photoluminescent nanostructure complexed to a sensing polymer, where the sensing polymer includes an organic polymer non-covalently bound to the photoluminescent nanostructure and an analyte-binding protein covalently bound to the organic polymer, and where the analyte-binding protein is capable of selectively binding the analyte, and the analyte-binding protein undergoes a substantial conformational change when binding the analyte. Separately, a composition for sensing an analyte, can include a complex, where the complex includes a photoluminescent nanostructure in an aqueous surfactant dispersion and a boronic acid capable of selectively reacting with an analyte. The compositions can be used in devices and methods for sensing an analyte. |
FILED | Tuesday, July 31, 2012 |
APPL NO | 13/562403 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1459 (20130101) Original (OR) Class A61B 5/14532 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/66 (20130101) G01N 33/542 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/54373 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981237 | Brujic et al. |
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FUNDED BY |
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APPLICANT(S) | New York University (New York, New York) |
ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
INVENTOR(S) | Jasna Brujic (New York, New York); Martin Haase (New York, New York) |
ABSTRACT | Multiple emulsions with an “onion” topology are useful vehicles for drug delivery, biochemical assays, and templating materials. They can be assembled by ternary liquid phase separation using microfluidics, but the control over their design is limited because the mechanism of their creation is unknown. Here it is shown that phase separation occurs via self-similar cycles of mass transfer, spinodal decomposition or nucleation, and coalescence into multiple layers. Mapping out the phase diagram demonstrates a linear relation between concentric layer diameters, whose slope depends on the initial ternary composition and the molecular weight of the surfactant. These general rules quantitatively predict the number of droplet layers (multiplicity). Further, self-assembly routes for polymer capsules and liposomes are provided with techniques to assemble lipid-stabilized droplets with ordered internal structures. |
FILED | Tuesday, August 18, 2015 |
APPL NO | 14/829578 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/11 (20130101) A61K 8/14 (20130101) A61K 9/113 (20130101) A61K 2800/10 (20130101) A61K 2800/80 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 5/045 (20130101) B01F 13/0059 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/00 (20130101) Original (OR) Class B01J 13/02 (20130101) B01J 13/06 (20130101) B01J 13/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09981377 | Morin et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Stephen A. Morin (Arlington, Massachusetts); Robert F. Shepherd (Brooktondale, New York); Adam Stokes (Watertown, Massachusetts); Filip Ilievski (Santa Clara, California); Ramses V. Martinez (Somerville, Massachusetts); Jamie L. Branch (Topeka, Kansas); Carina R. Fish (Cambridge, Massachusetts); Lihua Jin (Somerville, Massachusetts); Rui M. D. Nunes (Somerville, Massachusetts); Zhigang Suo (Lexington, Massachusetts); George M. Whitesides (Newton, Massachusetts) |
ABSTRACT | Systems and methods for providing flexible robotic actuators are disclosed. Some embodiments of the disclosed subject matter include a soft robot capable of providing a radial deflection motions; a soft tentacle actuator capable of providing a variety of motions and providing transportation means for various types of materials; and a hybrid robotic system that retains desirable characteristics of both soft robots and hard robots. Some embodiments of the disclosed subject matter also include methods for operating the disclosed robotic systems. |
FILED | Monday, September 08, 2014 |
APPL NO | 14/480106 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Domestic Washing or Cleaning; Suction Cleaners in General A47L 9/2836 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) Original (OR) Class B25J 9/1075 (20130101) B25J 9/1697 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/22 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/20305 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982070 | Matyjaszewski et al. |
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FUNDED BY |
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APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania); Pawel Chmielarz (Pittsburgh, Pennsylvania); Dominik Konkolewicz (West Chester, Ohio); Pawel Krys (Pittsburgh, Pennsylvania); Xiangcheng Pan (Pittsburgh, Pennsylvania); Valerie Williams (Pittsburgh, Pennsylvania) |
ABSTRACT | A process for polymerizing radically (co)polymerizable monomers at a temperature between −10° C. and 110° C. in an aqueous system comprising one or more radically (co)polymerizable monomer(s) is disclosed, and includes a molar excess of a ligand forming a soluble transition metal complex with an added transition metal salt that participates in a reversible reduction-oxidation cycle with one of an added site specific functional initiator and a dormant polymer chain having a radically transferable atom or group. The initial soluble catalyst complex concentration in the higher oxidation state is less than or equal to 2500 ppm. The reaction is conducted in the presence of an activator regenerator. The mole fraction of the soluble lower activator oxidation state transition metal formed by action of the activator regenerator, to transition metal in a higher deactivator oxidation state is less than 10%. The formed polymer chains have a dispersity of less than 1.5. |
FILED | Tuesday, January 12, 2016 |
APPL NO | 14/993632 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/40 (20130101) C08F 4/50 (20130101) C08F 120/28 (20130101) Original (OR) Class C08F 220/54 (20130101) C08F 2438/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982209 | Junk et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC (Gainesville, Florida) |
INVENTOR(S) | Christopher P. Junk (Wilmington, Delaware); Gregory Scott Blackman (Media, Pennsylvania); Steven R. Lustig (Landenberg, Pennsylvania); Mark D. Wetzel (Newark, Delaware); Wallace Gregory Sawyer (Gainesville, Florida); Brandon A. Krick (Gainesville, Florida) |
ABSTRACT | A low-wear fluoropolymer composite body comprises at least one fluoropolymer and additive particles dispersed therein. Also provided is a process for the fabrication of such a fluoropolymer composite body. The composite body exhibits a low wear rate for sliding motion against a hard counterface, and may be formulated with either melt-processible or non-melt-processible fluoropolymers. |
FILED | Friday, December 20, 2013 |
APPL NO | 14/136672 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/303 (20130101) C04B 26/08 (20130101) C04B 26/08 (20130101) C04B 35/117 (20130101) C04B 2111/00008 (20130101) C04B 2111/00362 (20130101) C04B 2235/444 (20130101) C04B 2235/3217 (20130101) C04B 2235/5454 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/22 (20130101) C08K 2003/2227 (20130101) C08K 2201/005 (20130101) Compositions of Macromolecular Compounds C08L 27/18 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 107/38 (20130101) C10M 125/10 (20130101) Original (OR) Class C10M 2201/062 (20130101) C10M 2201/062 (20130101) C10M 2201/062 (20130101) C10M 2201/105 (20130101) C10M 2213/043 (20130101) C10M 2213/0623 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2210/03 (20130101) C10N 2210/04 (20130101) C10N 2220/082 (20130101) C10N 2230/06 (20130101) C10N 2240/02 (20130101) C10N 2250/08 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/201 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/25 (20150115) Y10T 428/256 (20150115) Y10T 428/257 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982344 | Winter et al. |
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FUNDED BY |
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APPLICANT(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
ASSIGNEE(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
INVENTOR(S) | Charles H. Winter (Bloomfield Hills, Michigan); Thomas J. Knisley (Monroe, Michigan) |
ABSTRACT | A method of forming a thin film on a substrate which includes a step of contacting a surface with a precursor compound having a transition metal and one or more alkyl-1,3-diazabutadiene ligands is provided. The resulting modified surface is then contacted with an activating compound. |
FILED | Wednesday, July 20, 2016 |
APPL NO | 15/215153 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/005 (20130101) C07F 13/005 (20130101) C07F 15/025 (20130101) C07F 15/045 (20130101) C07F 15/065 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/45527 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982356 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Joseph Wang (San Diego, California); Wei Gao (La Jolla, California); Sirilak Sattayasamitsathit (San Diego, California) |
ABSTRACT | Methods, structures, devices and systems are disclosed for fabrication of microtube engines using membrane template electrodeposition. Such nanomotors operate based on bubble-induced propulsion in biological fluids and salt-rich environments. In one aspect, fabricating microengines includes depositing a polymer layer on a membrane template, depositing a conductive metal layer on the polymer layer, and dissolving the membrane template to release the multilayer microtubes. |
FILED | Monday, May 23, 2016 |
APPL NO | 15/161615 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/70 (20130101) A61K 47/02 (20130101) A61K 47/34 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) B01J 23/42 (20130101) B01J 23/892 (20130101) B01J 23/8906 (20130101) B01J 23/8913 (20130101) B01J 31/06 (20130101) B01J 35/02 (20130101) B01J 35/0006 (20130101) B01J 35/0033 (20130101) B01J 37/0215 (20130101) B01J 37/0244 (20130101) B01J 2231/005 (20130101) B01J 2531/005 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/02 (20130101) Original (OR) Class C25D 1/006 (20130101) C25D 1/20 (20130101) C25D 3/12 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 99/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48707 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982663 | Liu |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
INVENTOR(S) | Shaorong Liu (Norman, Oklahoma) |
ABSTRACT | An electroosmotic pump unit includes at least a first pump element, at least a second pump element, and an electrode. Each pump element includes a tube, an electrically grounded fluid inlet, a fluid outlet electrically coupled to the electrode, and a porous monolith immobilized in the tube and having open pores having net surface charges. When the electrode applies a voltage across the monoliths, a fluid supplied to the first pump element flows through the pump elements in a direction from a fluid inlet of the first pump element toward a fluid outlet of the second pump element. A plurality of electroosmotic pump units may be connected in series in a pump assembly. The electroosmotic pump unit, or pump assembly, may be connected to an apparatus such as a HPLC. |
FILED | Friday, October 10, 2014 |
APPL NO | 14/511860 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Separation B01D 61/427 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 19/04 (20130101) F04B 19/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983012 | Young et al. |
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FUNDED BY |
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APPLICANT(S) | TRX Systems, Inc. (Greenbelt, Maryland) |
ASSIGNEE(S) | TRX SYSTEMS, INC. (Greenbelt, Maryland) |
INVENTOR(S) | Travis Young (Rockville, Maryland); Kamiar Kordari (McLean, Virginia); Benjamin Funk (Hanover, Maryland); Carole Teolis (Glenn Dale, Maryland) |
ABSTRACT | A location and mapping service is described that creates a global database of indoor navigation maps through crowd-sourcing and data fusion technologies. The navigation maps consist of a database of geo-referenced, uniquely described features in the multi-dimensional sensor space (e.g., including structural, RF, magnetic, image, acoustic, or other data) that are collected automatically as a tracked mobile device is moved through a building (e.g. a person with a mobile phone or a robot). The feature information can be used to create building models as one or more tracked devices traverse a building. |
FILED | Thursday, April 14, 2016 |
APPL NO | 15/099361 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/32 (20130101) G01C 21/165 (20130101) G01C 21/206 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0252 (20130101) G01S 19/13 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983058 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | YuHuang Wang (Laurel, Maryland); Hyejin Kwon (Greenbelt, Maryland); Mijin Kim (Silver Spring, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | YuHuang Wang (Laurel, Maryland); Hyejin Kwon (Greenbelt, Maryland); Mijin Kim (Silver Spring, Maryland) |
ABSTRACT | The present invention relates to near-infrared quantum emitters, and in particular carbon nanostructures with chemically incorporated fluorescent defects, and methods of synthesizing near-infrared emitting nanostructures. |
FILED | Tuesday, May 09, 2017 |
APPL NO | 15/590397 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/128 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 49/006 (20130101) H01L 51/5262 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983111 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Chang-Jin Kim (Beverly Hills, California); Muchen Xu (Los Angeles, California) |
ABSTRACT | A low-profile shear-sensing unit includes a floating plate surrounded by a frame and a displacement sensor that measures in-plane movement of the floating plate. Covered with a surface sample, the floating plate is displaced by the friction drag (i.e., shear) on the surface caused by the flow of fluid and the in-plane displacement is measured by the displacement sensor. The shear force on the sample surface is then obtained by multiplying the measured displacement and the spring constant of the flexure beams, which suspend the floating plate. The floating plate and the flexure beams are formed out of one plate or substrate to achieve monolithic construction with a beam geometry that leads to a high-resolution measurement. |
FILED | Friday, November 18, 2016 |
APPL NO | 15/356062 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 13/02 (20130101) Original (OR) Class G01N 2013/0216 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983183 | Motayed et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia); George Mason University (Fairfax, Virginia); The George Washington University (Washington, District of Columbia) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia); George Mason University (Fairfax, Virginia); The George Washington University (Washington, District of Columbia) |
INVENTOR(S) | Abhishek Motayed (Rockville, Maryland); Geetha Aluri (Clifton Park, New York); Albert V. Davydov (North Potomac, Maryland); Mulpuri V. Rao (Fairfax Station, Virginia); Vladimir P. Oleshko (Gaithersburg, Maryland); Ritu Bajpai (Santa Clara, California); Mona E. Zaghloul (Bethesda, Maryland); Brian Thomson (Washington, District of Columbia); Baomei Wen (Gaithersburg, Maryland); Ting Xie (Burtonsville, Maryland); Guannan Liu (Portland, Oregon); Ratan Debnath (Damascus, Maryland) |
ABSTRACT | A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte. |
FILED | Wednesday, October 19, 2016 |
APPL NO | 15/297693 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 33/004 (20130101) G01N 33/005 (20130101) G01N 33/0031 (20130101) G01N 33/0037 (20130101) G01N 33/0042 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) G01N 33/0049 (20130101) G01N 33/0054 (20130101) G01N 33/0057 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/245 (20180101) Y02A 50/246 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983206 | Bailey et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Ryan C. Bailey (Urbana, Illinois); Matthew S. Luchansky (Allison Park, Pennsylvania); Abraham J. Qavi (Champaign, Illinois); Jared T. Kindt (Champaign, Illinois) |
ABSTRACT | Embodiments of the methods, compositions, and systems provided herein relate to enzymatic enhancement of immunoassays using photonic sensor arrays. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/209746 |
ART UNIT | 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54373 (20130101) Original (OR) Class G01N 2333/55 (20130101) G01N 2333/5412 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983298 | White |
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FUNDED BY |
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APPLICANT(S) | Associated Universities, Inc. (Washington, District of Columbia) |
ASSIGNEE(S) | Associated Universities, LLC (Washington, District of Columbia) |
INVENTOR(S) | Steven White (Arbovale, West Virginia) |
ABSTRACT | Laser rangefinders and methods of using laser rangefinders are disclosed. One embodiment of a laser rangefinder includes a first DDS (direct digital synthesizer) outputting a first reference signal, an isolated laser source that receives the first signal and outputs an optical signal, a collimating lens coupled to the isolated laser source adapted to direct the optical signal to free space, a collecting lens positioned adjacent to the collimating lens adapted to receive a modulated optical signal from free space, a pin diode detector coupled to collecting lens, a second DDS outputting a second reference signal, and a computing device adapted to receive the first reference signal, the second reference signal, and the received modulated optical signal and calculate a distance. |
FILED | Tuesday, February 02, 2016 |
APPL NO | 15/013251 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4818 (20130101) Original (OR) Class G01S 17/10 (20130101) G01S 17/36 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983412 | Fuchs et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
INVENTOR(S) | Henry Fuchs (Chapel Hill, North Carolina); David Scott Dunn (Chapel Hill, North Carolina); Cary Aaron Tippets (Durham, North Carolina) |
ABSTRACT | A head mountable augmented reality see through near eye display system includes a see through augmented reality image focal distance modulator for changing a distance at which augmented reality images appear in focus and including at least one light transmissive surface through which real world objects are viewable. The system further includes a display for generating an augmented reality image and projecting the augmented reality image onto the see through augmented reality image focal distance modulator. The system further includes an augmented reality image focal distance controller for controlling the see through augmented reality image focal distance modulator to cause the augmented reality image to appear in focus a distance corresponding to a vergence distance and for changing the distance at which the augmented reality image appears to be in focus in correspondence with changes in the vergence distance. |
FILED | Thursday, February 02, 2017 |
APPL NO | 15/423198 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/0825 (20130101) G02B 27/0172 (20130101) G02B 27/0179 (20130101) Original (OR) Class G02B 2027/0185 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984147 | Long et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
ASSIGNEE(S) | The Research Foundation for the State University of New York (Binghamton, New York) |
INVENTOR(S) | Bo Long (Palo Alto, California); Zhongfei Mark Zhang (Vestal, New York) |
ABSTRACT | Relational clustering has attracted more and more attention due to its phenomenal impact in various important applications which involve multi-type interrelated data objects, such as Web mining, search marketing, bioinformatics, citation analysis, and epidemiology. A probabilistic model is presented for relational clustering, which also provides a principal framework to unify various important clustering tasks including traditional attributes-based clustering, semi-supervised clustering, co-clustering and graph clustering. The model seeks to identify cluster structures for each type of data objects and interaction patterns between different types of objects. Under this model, parametric hard and soft relational clustering algorithms are provided under a large number of exponential family distributions. The algorithms are applicable to relational data of various structures and at the same time unify a number of state-of-the-art clustering algorithms: co-clustering algorithms, the k-partite graph clustering, and semi-supervised clustering based on hidden Markov random fields. |
FILED | Friday, June 17, 2016 |
APPL NO | 15/186063 |
ART UNIT | 2167 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 17/30598 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 99/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985148 | Sureshkumar et al. |
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FUNDED BY |
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APPLICANT(S) | Radhakrishna Sureshkumar (Syracuse, New York); Miriam Israelowitz (Syracuse, New York) |
ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
INVENTOR(S) | Radhakrishna Sureshkumar (Syracuse, New York); Miriam Israelowitz (Syracuse, New York) |
ABSTRACT | There is set forth herein a method for forming a suspension having nanoparticles. There is also set forth herein a method for making an interface including nanoparticles. A morphology of conductive nanoparticle interface is set forth herein. |
FILED | Wednesday, November 27, 2013 |
APPL NO | 14/092582 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/054 (20141201) H01L 31/1085 (20130101) H01L 31/02168 (20130101) H01L 31/02327 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985231 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
ASSIGNEE(S) | NUtech Ventures, Inc. (Lincoln, Nebraska) |
INVENTOR(S) | Jinsong Huang (Lincoln, Nebraska); Zhengguo Xiao (Lincoln, Nebraska) |
ABSTRACT | Systems and methods are described to form compositionally graded BHJ structures utilizing solvent-fluxing techniques. In implementations, the systems and methods described herein involve a high boiling point additive, a solution of a polymer donor and an acceptor, a substrate material, a working solvent, and a flux solvent for formation of compositionally graded BHJ structures. |
FILED | Friday, February 12, 2016 |
APPL NO | 15/042692 |
ART UNIT | 1756 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0036 (20130101) H01L 51/0037 (20130101) H01L 51/0043 (20130101) H01L 51/0047 (20130101) H01L 51/4253 (20130101) Original (OR) Class H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985296 | Asefa et al. |
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FUNDED BY |
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APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
INVENTOR(S) | Tewodros Asefa (Princeton, New Jersey); Rafael Silva (Piscataway, New Jersey) |
ABSTRACT | Electrocatalytic polyaniline-derived mesoporous carbon nanoparticles and methods of synthesizing and using the same are provided. |
FILED | Friday, March 07, 2014 |
APPL NO | 14/200833 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/00 (20130101) C01B 31/02 (20130101) C01B 37/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/90 (20130101) H01M 4/96 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985460 | Georgakopoulos et al. |
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FUNDED BY |
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APPLICANT(S) | Stavros Georgakopoulos (Boca Raton, Florida); Kun Bao (Miami, Florida) |
ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
INVENTOR(S) | Stavros Georgakopoulos (Boca Raton, Florida); Kun Bao (Miami, Florida) |
ABSTRACT | Novel and advantageous systems and methods for wireless power transfer (WPT) via multiple-resonator conformal strongly coupledmagnetic resonance (CSCMR) are provided. Instead of using a single loop as a resonator, multiple resonators can be used. This leads to lower operating frequency (e.g., 30% decrease), extended WPT range (e.g., 20% increase), and higher WPT efficiency compared to single-resonator systems of the same size. |
FILED | Friday, July 17, 2015 |
APPL NO | 14/802794 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) Original (OR) Class H02J 50/12 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09986440 | Guvenc |
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FUNDED BY |
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APPLICANT(S) | Ismail Guvenc (Raleigh, North Carolina) |
ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
INVENTOR(S) | Ismail Guvenc (Raleigh, North Carolina) |
ABSTRACT | Techniques and systems are disclosed for addressing the challenges in interference and mobility management in broadband, UAV-assisted heterogeneous network (BAHN) scenarios. Implementations include BAHN control components, for example, at a controlling network node of a BAHN. Generally, a component implementing techniques for managing interference and handover in a BAHN gathers state data from network nodes or devices in the BAHN, determines a candidate BAHN model that optimizes interference and handover metrics, and determines and performs model adjustments to the network parameters, BS parameters, and UAV-assisted base station (UABS) device locations and velocities to conform to the optimized candidate BAHN model. Also described is a UABS apparatus having a UAV, communications interface for communicating with a HetNet in accordance with wireless air interface standards, and a computing device suitable for implementing BAHN control or reinforcement learning components. |
FILED | Monday, February 27, 2017 |
APPL NO | 15/443147 |
ART UNIT | 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Transmission H04B 7/18504 (20130101) Wireless Communication Networks H04W 4/22 (20130101) H04W 4/90 (20180201) H04W 16/14 (20130101) H04W 16/22 (20130101) Original (OR) Class H04W 16/28 (20130101) H04W 36/20 (20130101) H04W 76/15 (20180201) H04W 76/025 (20130101) H04W 84/042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09986663 | Broido et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | David A. Broido (Needham, Massachusetts); Thomas L. Reinecke (Alexandria, Virginia); Lucas R. Lindsay (Alexandria, Virginia) |
ABSTRACT | High thermal conductivity materials and methods of their use for thermal management applications are provided. In some embodiments, a device comprises a heat generating unit (304) and a thermally conductive unit (306, 308, 310) in thermal communication with the heat generating unit (304) for conducting heat generated by the heat generating unit (304) away from the heat generating unit (304), the thermally conductive unit (306, 308, 310) comprising a thermally conductive compound, alloy or composite thereof. The thermally conductive compound may include Boron Arsenide, Boron Antimonide, Germanium Carbide and Beryllium Selenide. |
FILED | Wednesday, January 29, 2014 |
APPL NO | 14/763993 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Couplings for Transmitting Rotation; Clutches; Brakes F16D 69/00 (20130101) F16D 69/02 (20130101) F16D 2066/001 (20130101) F16D 2200/0047 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/3731 (20130101) H01L 23/3738 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20481 (20130101) Original (OR) Class H05K 7/20509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 09981389 | Kennedy et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Brett A. Kennedy (Pasadena, California); Matthew A. Frost (Pasadena, California); John M. Leichty (Pasadena, California); Michael J. Hagman (Pasadena, California); James W. Borders (Pasadena, California); Jamie S. Piacentine (Pasadena, California); Charles F. Bergh (Pasadena, California); Allen R. Sirota (Pasadena, California); Kalind C. Carpenter (Pasadena, California) |
ABSTRACT | Manipulators in accordance with various embodiments of the invention can be utilized to implement statically stable robots capable of both dexterous manipulation and versatile mobility. Manipulators in accordance with one embodiment of the invention include: an azimuth actuator; three elbow joints that each include two actuators that are offset to allow greater than 360 degree rotation of each joint; a first connecting structure that connects the azimuth actuator and a first of the three elbow joints; a second connecting structure that connects the first elbow joint and a second of the three elbow joints; a third connecting structure that connects the second elbow joint to a third of the three elbow joints; and an end-effector interface connected to the third of the three elbow joints. |
FILED | Tuesday, March 03, 2015 |
APPL NO | 14/637278 |
ART UNIT | 3652 — Material and Article Handling |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) B25J 15/08 (20130101) Original (OR) Class Motor Vehicles; Trailers B62D 57/032 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/28 (20130101) Y10S 901/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982330 | Manuel et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainsville, Florida) |
INVENTOR(S) | Michele Viola Manuel (Gainesville, Florida); Derek Hsen Dai Hsu (Gainesville, Florida) |
ABSTRACT | Disclosed herein is a shape memory alloy comprising 48 to 50 atomic percent nickel, 15 to 30 atomic percent hathium, 1 to 5 atomic percent aluminum; with the remainder being titanium. Disclosed herein too is a method of manufacturing a shape memory alloy comprising mixing together to form an alloy nickel, hafnium, aluminum and titanium in amounts of 48 to 50 atomic percent nickel, 15 to 30 atomic percent hafnium, 1 to 5 atomic percent aluminum; with the remainder being titanium; solution treating the alloy at a temperature of 700 to 1300° C. for 50 to 200 hours; and aging the alloy at a temperature of 400 to 800° C. for a time period of 50 to 200 hours to form a shape memory alloy. |
FILED | Tuesday, November 25, 2014 |
APPL NO | 14/552988 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Alloys C22C 1/00 (20130101) C22C 27/00 (20130101) C22C 30/00 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/006 (20130101) C22F 1/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09982661 | Trigwell et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Adm. (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Steven Trigwell (Merritt Island, Florida); James E. Fesmire (Titusville, Florida); Tracy L. Gibson (Melbourne, Florida); Martha K. Williams (Titusville, Florida) |
ABSTRACT | A thermal management system includes a first substrate having a first conductive inner surface. A second substrate has a second conductive inner surface. A connecting structure is attached to the first and second substrates to space apart the first and second inner surfaces defining an insulating space for a single architecture. One or more passively-acting elements are attached to the inner surface of at least one substrate and including a shape memory material such as a shape memory alloy (SMA). The SMA passively reacts to the temperature of the first substrate by thermally contacting or separating from the second inner surface of the second substrate for the control of the conduction of heat energy in either direction. |
FILED | Tuesday, March 11, 2014 |
APPL NO | 14/205250 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 5/00 (20130101) F28F 2013/008 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09984785 | Roberson et al. |
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FUNDED BY |
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APPLICANT(S) | Luke B. Roberson (Titusville, Florida); Martha K. Williams (Titusville, Florida); Tracy L. Gibson (Melbourne, Florida); LaNetra C. Tate (Oviedo, Florida); Sarah J. Snyder (Terre Haute, Indiana); Craig R. Fortier (Cocoa, Florida) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of NASA (Washinton, District of Columbia) |
INVENTOR(S) | Luke B. Roberson (Titusville, Florida); Martha K. Williams (Titusville, Florida); Tracy L. Gibson (Melbourne, Florida); LaNetra C. Tate (Oviedo, Florida); Sarah J. Snyder (Terre Haute, Indiana); Craig R. Fortier (Cocoa, Florida) |
ABSTRACT | Systems and methods for forming conductive materials. The conductive materials can be applied using a printer in single or multiple passes onto a substrate. The conductive materials are composed of electrical conductors such as carbon nanotubes (including functionalized carbon nanotubes and metal-coated carbon nanotubes), grapheme, a polycyclic aromatic hydrocarbon (e.g. pentacene and bisperipentacene), metal nanoparticles, an inherently conductive polymer (ICP), and combinations thereof. Once the conductive materials are applied, the materials are dried and sintered to form adherent conductive materials on the substrate. The adherent conductive materials can be used in applications such as damage detection, particle removal, and smart coating systems. |
FILED | Friday, October 21, 2011 |
APPL NO | 13/278710 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/26 (20130101) B05D 5/12 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/006 (20130101) B41M 5/0023 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/18 (20130101) C23C 18/31 (20130101) C23C 18/1262 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 1/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985431 | Wohlfarth |
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FUNDED BY |
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APPLICANT(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
INVENTOR(S) | Scott C. Wohlfarth (Edgerton, Wisconsin) |
ABSTRACT | Embodiments are directed to a current limiter having an inrush limiting stage and a discharge limiting stage. The inrush limiting stage is communicatively coupled in series with the discharge limiting stage. The inrush limiting stage is configured to receive a first input current in a first direction, perform an inrush limiting operation on the first input current and pass an inrush limited output current in the first direction to the discharge limiting stage. The discharge limiting stage is configured to pass the inrush limited output current substantially unchanged in the first direction. The discharge limiting stage is further configured to receive a second input current in a second direction, perform a discharge limiting operation on the second input current and pass a discharge limited output current in the second direction to the inrush limiting stage. The inrush limiting stage is further configured to pass the discharge limited output current substantially unchanged in the second direction. |
FILED | Monday, October 19, 2015 |
APPL NO | 14/886788 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Emergency Protective Circuit Arrangements H02H 9/001 (20130101) H02H 9/02 (20130101) Original (OR) Class H02H 9/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985594 | Quilligan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Gerard T. Quilligan (Gulf Breeze, Florida); Shahid Aslam (Washington, District of Columbia) |
ABSTRACT | A Gated CDS Integrator (GCI) may amplify low-level signals without introducing excessive offset and noise. The GCI may also amplify the low level signals with accurate and variable gain. The GCI may include a modulator preceding a linear amplifier such that offset or noise present in a signal path between the modulator and a demodulator input is translated to a higher out of band frequency. |
FILED | Tuesday, September 08, 2015 |
APPL NO | 14/847907 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Amplifiers H03F 1/26 (20130101) H03F 3/72 (20130101) H03F 3/387 (20130101) Original (OR) Class H03F 3/45475 (20130101) H03F 3/45596 (20130101) H03F 2200/264 (20130101) H03F 2200/271 (20130101) H03F 2200/372 (20130101) H03F 2203/45212 (20130101) H03F 2203/45288 (20130101) H03F 2203/45514 (20130101) Control of Amplification H03G 3/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 09982316 | Qiao et al. |
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FUNDED BY |
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APPLICANT(S) | Virent, Inc. (Madison, Wisconsin) |
ASSIGNEE(S) | Virent, Inc. (Madison, Wisconsin) |
INVENTOR(S) | Ming Qiao (Pewaukee, Wisconsin); Randy D. Cortright (Madison, Wisconsin); Elizabeth Woods (Middleton, Wisconsin) |
ABSTRACT | The present invention provides processes for catalytic deconstruction of biomass using a solvent produced in a bioreforming reaction. |
FILED | Monday, August 21, 2017 |
APPL NO | 15/682125 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/34 (20130101) B01J 23/52 (20130101) B01J 23/462 (20130101) B01J 23/464 (20130101) B01J 23/687 (20130101) B01J 23/6527 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 63/00 (20130101) Acyclic or Carbocyclic Compounds C07C 29/132 (20130101) Polysaccharides; Derivatives Thereof C08B 30/12 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/06 (20130101) C10G 1/065 (20130101) C10G 3/42 (20130101) C10G 3/47 (20130101) C10G 2300/44 (20130101) C10G 2300/805 (20130101) C10G 2300/1011 (20130101) C10G 2300/1014 (20130101) C10G 2400/30 (20130101) Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 1/02 (20130101) Original (OR) Class C13K 13/00 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101) Y02P 30/42 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09983183 | Motayed et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia); George Mason University (Fairfax, Virginia); The George Washington University (Washington, District of Columbia) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia); George Mason University (Fairfax, Virginia); The George Washington University (Washington, District of Columbia) |
INVENTOR(S) | Abhishek Motayed (Rockville, Maryland); Geetha Aluri (Clifton Park, New York); Albert V. Davydov (North Potomac, Maryland); Mulpuri V. Rao (Fairfax Station, Virginia); Vladimir P. Oleshko (Gaithersburg, Maryland); Ritu Bajpai (Santa Clara, California); Mona E. Zaghloul (Bethesda, Maryland); Brian Thomson (Washington, District of Columbia); Baomei Wen (Gaithersburg, Maryland); Ting Xie (Burtonsville, Maryland); Guannan Liu (Portland, Oregon); Ratan Debnath (Damascus, Maryland) |
ABSTRACT | A nanostructure sensing device comprises a semiconductor nanostructure having an outer surface, and at least one of metal or metal-oxide nanoparticle clusters functionalizing the outer surface of the nanostructure and forming a photoconductive nanostructure/nanocluster hybrid sensor enabling light-assisted sensing of a target analyte. |
FILED | Wednesday, October 19, 2016 |
APPL NO | 15/297693 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 33/004 (20130101) G01N 33/005 (20130101) G01N 33/0031 (20130101) G01N 33/0037 (20130101) G01N 33/0042 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) G01N 33/0049 (20130101) G01N 33/0054 (20130101) G01N 33/0057 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/245 (20180101) Y02A 50/246 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 09983102 | Staymates et al. |
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FUNDED BY |
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APPLICANT(S) | Matthew Staymates (Germantown, Maryland); Stefan Robert Lukow (Galloway, New Jersey) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Matthew Staymates (Germantown, Maryland); Stefan Robert Lukow (Galloway, New Jersey) |
ABSTRACT | The apparatus disclosed herein pertains to the detection of trace explosives or narcotics detection. The apparatus comprises the front-end particle dislodge and sample intake portion of a chemical trace detection system utilizing aerodynamic flow as a transport mechanism whereby compounds indicative of explosives or narcotics contamination are liberated from target surfaces of foot or footwear and then transported by air flow to a sample accumulation feature for chemical analysis. The apparatus is intended for inclusion with additional components, such as an efficient pre-concentrator, a thermal desorption unit, and a chemical analyzer/detector to achieve a complete trace detection system. |
FILED | Thursday, April 05, 2012 |
APPL NO | 13/440857 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/22 (20130101) Original (OR) Class G01N 2001/022 (20130101) G01N 2001/024 (20130101) G01N 2001/2223 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 09980863 | Hansen et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
INVENTOR(S) | Andrew H. Hansen (Minneapolis, Minnesota); Gary D. Goldish (Minneapolis, Minnesota); Eric Nickel (Minneapolis, Minnesota) |
ABSTRACT | A manual wheelchair including a collapsible frame having a first lateral member that is connected to first and second braces at their respective first ends. A drive wheel axle extends along a first axis of rotation and engages a drive wheel, the first brace, and a portion of a transmission. A push rim axle extends along a second axis of rotation and engages a push rim wheel, the second brace, and a portion of the transmission, which transmits rotation of the push rim to rotation of the drive wheel. The collapsible frame additionally includes a second lateral member that is connected to the first and second braces as their respective second ends. The first and second braces are configured to release the second lateral member to collapse the manual wheelchair. |
FILED | Monday, October 23, 2017 |
APPL NO | 15/791231 |
ART UNIT | 3618 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/023 (20130101) Original (OR) Class A61G 5/026 (20130101) A61G 5/0825 (20161101) A61G 5/0875 (20161101) A61G 5/1054 (20161101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 09984143 | Luo et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Gang Luo (Salt Lake City, Utah); Chunqiang Tang (Ossining, New York); Philip Shi-lung Yu (Chappaqua, New York) |
ABSTRACT | There are provided a system and method for resource adaptive, real-time new event detection. The method includes capturing, from among documents in a document streaming environment that includes a plurality of remote streaming document sources, first-story documents. The method further includes storing any of the documents determined to be the first-story documents in a memory. The method also includes classifying the documents as important or non-important based on pre-specified criteria. The method additionally includes storing, in the memory, only information of the documents classified as important, when the memory overflows. The method further includes discarding the documents that are classified as non-important when a document consumption rate from the memory is less than a document insertion rate into the memory. The method additionally includes removing the information of the documents classified as important from the memory subsequent to one of consumption and processing by a consumer. |
FILED | Wednesday, March 25, 2015 |
APPL NO | 14/668561 |
ART UNIT | 2178 — Graphical User Interface and Document Processing |
CURRENT CPC | Electric Digital Data Processing G06F 17/30011 (20130101) G06F 17/30117 (20130101) G06F 17/30312 (20130101) G06F 17/30516 (20130101) G06F 17/30598 (20130101) Original (OR) Class G06F 17/30684 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
US 09985193 | Dial et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Oliver Dial (Yorktown Heights, New York); Jay M. Gambetta (Yorktown Heights, New York); Douglas T. McClure, III (Rye, New York); Matthias Steffen (Cortlandt Manor, New York) |
ABSTRACT | A technique relates a superconducting microwave cavity. An array of posts has different heights in the cavity, and the array supports a localized microwave mode. The array of posts includes lower resonant frequency posts and higher resonant frequency posts. The higher resonant frequency posts are arranged around the lower resonant frequency posts. A first plate is opposite a second plate in the cavity. One end of the lower resonant frequency posts is positioned on the second plate so as to be electrically connected to the second plate. Another end of the lower resonant frequency posts in the array is open so as not to form an electrical connection to the first plate. Qubits are connected to the lower resonant frequency posts in the array of posts, such that each of the qubits is physically connected to one or two of the lower resonant frequency posts in the array of posts. |
FILED | Tuesday, June 30, 2015 |
APPL NO | 14/755181 |
ART UNIT | 2827 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/14 (20130101) H01L 39/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
US 09980635 | Manquez Hatta et al. |
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FUNDED BY |
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APPLICANT(S) | EYECARE S.A. (Santiago, Chile) |
ASSIGNEE(S) | EYECARE S.A. (Santiago, Chile) |
INVENTOR(S) | Maria Eliana Manquez Hatta (Santiago, Chile); Humberto Lobos Sucarrat (Santiago, Chile) |
ABSTRACT | A system for preliminary diagnosis of ocular diseases is proposed, in which from capturing a plurality of images of the eyes of a person, a final image, corrected by processing the images by a computer application, is obtained. The already mentioned application calculates the percentage of the colors composing the pupillary reflex of each eye, and compares the results with previous reference pictures obtained from normal cases and clinical cases of ocular diseases. |
FILED | Wednesday, January 14, 2015 |
APPL NO | 14/597213 |
ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/0025 (20130101) Original (OR) Class A61B 3/112 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 09982353 | Masel et al. |
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FUNDED BY |
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APPLICANT(S) | Dioxide Materials, Inc. (Boca Raton, Florida) |
ASSIGNEE(S) | Dioxide Materials, Inc. (Boca Raton, Florida) |
INVENTOR(S) | Richard I. Masel (Boca Raton, Illinois); Zengcai Liu (Boca Raton, Florida) |
ABSTRACT | Water electrolyzers employs base metal catalysts and an anion-conducting polymeric membrane comprising a polymer of styrene, vinylbenzyl-Rs and possibly vinylbenzyl-Rx. Rs is a positively charged cyclic amine group. Rx is at least one constituent selected from the group consisting of —Cl, —OH, and a reaction product between an —OH or —Cl and a species other than a simple amine or a cyclic amine. |
FILED | Monday, January 16, 2017 |
APPL NO | 15/406909 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/10 (20130101) C25B 9/10 (20130101) C25B 13/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 09985198 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | HRL LABORATORIES LLC. (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | David T. Chang (Calabasas, California); Frederic P. Stratton (Beverly Hills, California); Hung Nguyen (Los Angeles, California); Randall L. Kubena (Oak Park, California) |
ABSTRACT | High-yield fabrication methods are provided for making quartz resonators having thicknesses ranging from one micrometer to several hundred micrometers and thus covering the frequency range from HF to UHF. Plasma dry etching is used to form arbitrary resonator geometries. The quartz resonator structure and the through-quartz vias are formed concurrently. The method includes bonding a quartz device wafer to a quartz handle wafer with a temporary adhesive. Mesa structures formed by plasma dry etching enable the resonators to achieve high-Q operation with energy trapping/mode confinement. A thermo-compression bond integrates the quartz resonators to a host wafer (e.g., an oscillator ASIC) to form oscillators. Silicon cap wafers are bonded over the resonators to the ASIC to provide wafer scale hermetic encapsulation of the quartz oscillators. |
FILED | Friday, May 23, 2014 |
APPL NO | 14/286419 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/23 (20130101) H01L 41/29 (20130101) H01L 41/053 (20130101) H01L 41/311 (20130101) Original (OR) Class H01L 41/332 (20130101) H01L 41/0475 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 29, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180529.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page