FedInvent™ Patents

Patent Details for Tuesday, June 05, 2018

This page was updated on Monday, March 27, 2023 at 05:33 AM GMT

Department of Health and Human Services (HHS)

09986724 — Genetically modified non-human animals and methods of use thereof

US 09986724	Flavell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland)
ASSIGNEE(S)	Regeneron Pharmaceuticals, Inc. (Tarrytown, New York); Yale University (New Haven, Connecticut); Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland)
INVENTOR(S)	Richard Flavell (Guilford, Connecticut); Till Strowig (Braunschweig, Germany); Markus G. Manz (Zollikon, Switzerland); Chiara Borsotti (Bronxville, New York); Madhav Dhodapkar (New Haven, Connecticut); Andrew J. Murphy (Croton-on-Hudson, New York); Sean Stevens (Del Mar, California); George D. Yancopoulos (Yorktown Heights, New York)
ABSTRACT	Genetically modified non-human animals are provided that may be used to model human hematopoietic cell development, function, or disease. The genetically modified non-human animals comprise a nucleic acid encoding human IL-6 operably linked to an IL-6 promoter. In some instances, the genetically modified non-human animal expressing human IL-6 also expresses at least one of human M-CSF, human IL-3, human GM-CSF, human SIRPa or human TPO. In some instances, the genetically modified non-human animal is immunodeficient. In some such instances, the genetically modified non-human animal is engrafted with healthy or diseased human hematopoietic cells. Also provided are methods for using the subject genetically modified non-human animals in modeling human hematopoietic cell development, function, and/or disease, as well as reagents and kits thereof that find use in making the subject genetically modified non-human animals and/or practicing the subject methods.
FILED	Friday, June 24, 2016
APPL NO	15/192903
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 67/0278 (20130101) Original (OR) Class A01K 2207/15 (20130101) A01K 2217/15 (20130101) A01K 2217/052 (20130101) A01K 2217/072 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/01 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Peptides C07K 14/535 (20130101) C07K 14/5403 (20130101) C07K 14/5412 (20130101)
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09986734 — Human and large-mammal lung bioreactor

US 09986734	Raredon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	YALE UNIVERSITY (New Haven, Connecticut); RAREDON RESOURCES, INC. (Northampton, Massachusetts)
ASSIGNEE(S)	Yale University (New Haven, Connecticut); Raredon Resources, Inc. (Northampton, Massachusetts)
INVENTOR(S)	Micha Sam Brickman Raredon (Somerville, Massachusetts); Tom Raredon (Northampton, Massachusetts); Laura Niklason (New Haven, Connecticut)
ABSTRACT	The present invention provides a bioreactor for large-mammal lung tissue. The bioreactor is capable of hydraulic driven negative-pressure and positive-pressure perfusion and ventilation. Perfusion and ventilation is delivered at physiological rates and is easily controllable. In one embodiment, the bioreactor comprises a support scaffold to support the size of a large-mammal lung tissue. In another embodiment, the bioreactor comprises a pleural sack that provides a small isolated fluid chamber which surrounds an engineered lung, thereby minimizing the amount of culture media needed. The present invention also provides an in vitro model for examining the function of a test agent and compositions and methods for alleviating a lung defect in a large-mammal.
FILED	Thursday, June 25, 2015
APPL NO	14/749889
ART UNIT	1799 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0263 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 35/42 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3804 (20130101) A61L 27/3839 (20130101) A61L 27/3895 (20130101) A61L 2430/40 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/00 (20130101) C12M 23/50 (20130101) C12M 23/52 (20130101) C12M 25/14 (20130101) C12M 29/10 (20130101) C12M 41/46 (20130101) C12M 41/48 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0688 (20130101) C12N 2533/90 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101)
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09986740 — Methods of identifying insect-TRPA1 modulators

US 09986740	Garrity et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	BRANDEIS UNIVERSITY (Waltham, Massachusetts)
ASSIGNEE(S)	Brandeis University (Waltham, Massachusetts)
INVENTOR(S)	Paul Garrity (Waltham, Massachusetts); Kyeongjin Kang (Waltham, Massachusetts)
ABSTRACT	The invention provides a screening method for identifying an insect-specific TRPA1 modulator by comparing modulation of an insect TRPA1 and a mammalian TRPA1. The invention further provides method of insect control by applying to an insect a insect-specific TRPA1 modulator identified by the screening method.
FILED	Monday, September 26, 2016
APPL NO	15/276682
ART UNIT	1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 35/02 (20130101) A01N 43/36 (20130101) A01N 47/48 (20130101) Original (OR) Class Fodder A23K 50/90 (20160501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/5085 (20130101) G01N 33/6872 (20130101) G01N 35/10 (20130101) G01N 2333/705 (20130101) G01N 2333/43552 (20130101) G01N 2333/43573 (20130101) G01N 2500/02 (20130101)
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09986905 — Predicting retinal degeneration based on three-dimensional modeling of oxygen concentration

US 09986905	McHugh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Schepens Eye Research Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	The Schepens Eye Research Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Kevin McHugh (Allston, Massachusetts); Magali Saint-Geniez (Somerville, Massachusetts); Leo Kim (Boston, Massachusetts)
ABSTRACT	In some example implementations, there is provided a method for predicting retinal degeneration in multiple eye diseases. The method may include receiving three-dimensional data representative of a plurality of layers of a retina of a subject under test; determining, from the received data, oxygen concentration at one or more of the plurality of layers; detecting, based on the determined oxygen concentration, a region of at least one a high oxygen concentration in the retina or a low oxygen concentration in the retina; and comparing the detected region to reference data to determine whether the retina including the detected region suffers from or will suffer from at least one of a retinal disease or a degeneration of the retina. Related apparatus are also disclosed.
FILED	Wednesday, April 23, 2014
APPL NO	14/786952
ART UNIT	2872 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/12 (20130101) A61B 3/0025 (20130101) Original (OR) Class A61B 3/102 (20130101) A61B 3/1005 (20130101) A61B 5/0066 (20130101) A61B 5/1455 (20130101) A61B 5/7275 (20130101)
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09986915 — Systems and methods for a short wave infrared device

US 09986915	Carr et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Boston, Massachusetts)
INVENTOR(S)	Jessica Carr (Fairmont, West Virginia); Oliver Bruns (Boston, Massachusetts); Moungi Bawendi (Cambridge, Massachusetts); Tulio Valdez (Simsbury, Connecticut)
ABSTRACT	Systems and methods for a short wave infrared (SWIR) otoscope device are provided. The SWIR otoscope device can capture images of a patient's middle ear to aid in diagnosing one of a plurality of maladies. In one embodiment, the SWIR otoscope device can include a SWIR detector, a light source, and a plurality of optics that can enable the SWIR otoscope device to capture images of the middle ear of a patient.
FILED	Wednesday, July 27, 2016
APPL NO	15/221517
ART UNIT	3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/07 (20130101) A61B 1/00009 (20130101) A61B 1/32 (20130101) A61B 1/227 (20130101) A61B 1/0646 (20130101) A61B 1/0684 (20130101) A61B 5/12 (20130101) A61B 5/0086 (20130101) Original (OR) Class A61B 5/7282 (20130101)
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09986973 — Method for shear wave ultrasound vibrometry with interleaved push and detection pulses

US 09986973	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Shigao Chen (Rochester, Minnesota); James F. Greenleaf (Rochester, Minnesota)
ASSIGNEE(S)	MAYO Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Shigao Chen (Rochester, Minnesota); James F. Greenleaf (Rochester, Minnesota)
ABSTRACT	A shear wave dispersion ultrasound vibrometry (“SDUV”) method for measuring a mechanical property of a subject is provided. Particularly, a set of ultrasonic vibration tone bursts is applied to a vibration origin in the subject so that harmonic vibratory motion is imparted to a tissue of interest. The set of vibration tone bursts effectively act like a single vibration pulse that imparts vibratory motion at larger amplitudes than achievable with a single pulse. Multiple ultrasonic detection pulses are then applied to two or more locations in the tissue of interest in order to measure shear waves propagating outward from the vibration origin. From these measurements, phase or amplitude information related to the shear wave propagation is determined and used to calculate a shear wave speed. Using the shear wave speed information, mechanical properties of the tissue are calculated.
FILED	Friday, April 22, 2011
APPL NO	13/092574
ART UNIT	3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/48 (20130101) Original (OR) Class A61B 8/485 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52022 (20130101) G01S 7/52042 (20130101)
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09987089 — Device and a method for imaging-guided photothermal laser therapy for cancer treatment

US 09987089	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	UNIVERSITY OF CENTRAL OKLAHOMA (Edmond, Oklahoma)
ASSIGNEE(S)	University of Central Oklahoma (Edmond, Oklahoma)
INVENTOR(S)	Wei R. Chen (Edmond, Oklahoma); Feifan Zhou (Edmond, Oklahoma); Zhifang Li (Fujian, China PRC); Hui Li (Fujian, China PRC)
ABSTRACT	This invention relates to a device and a method for monitoring and optimizing photothermal therapy, using a high-power continuous-wave laser beam and a pulsed laser beam, both transmitted through a single soft, multi-mode optical fiber with a diffuse active tip, to interstitially irradiate the target tissue at the same time. The continuous-wave laser light induces photothermal effect and increases tissue temperature and the pulsed laser light produces a photoacoustic signal. The photoacoustic signal intensity is used to monitor the temperature changes in the target tissue and to guide the irradiation of the high-power laser to optimize the photothermal effect by adjusting the light intensity and irradiation time.
FILED	Monday, July 13, 2015
APPL NO	14/797430
ART UNIT	3769 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0095 (20130101) A61B 5/4836 (20130101) A61B 18/22 (20130101) Original (OR) Class A61B 2018/00702 (20130101) A61B 2018/00761 (20130101) A61B 2018/00791 (20130101) A61B 2018/2005 (20130101) A61B 2018/2025 (20130101) A61B 2018/2261 (20130101)
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09987135 — Devices and methods for treating functional tricuspid valve regurgitation

US 09987135	Lederman et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Robert J. Lederman (Chevy Chase, Maryland); Kanishka Ratnayaka (Washington, District of Columbia); Toby Rogers (Washington, District of Columbia)
ABSTRACT	Disclosed here are devices and methods for treating functional tricuspid valve regurgitation and related conditions. Disclosed devices are adapted for applying force to an area of a patient's heart along or near the atrioventricular groove, and can include a tensioning element configured to be delivered by a flexible member guided through a catheter and positioned generally along or near the atrioventricular groove, and a compression member positionable along the tensioning element and over a desired segment of the atrioventricular groove to develop force to be applied to an adjacent area of the heart by selective tensioning of the tensioning element.
FILED	Thursday, March 13, 2014
APPL NO	14/776488
ART UNIT	3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2442 (20130101) A61F 2/2481 (20130101) Original (OR) Class A61F 2002/2484 (20130101) A61F 2220/0016 (20130101)
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09987242 — Treatment of Levodopa-induced Dyskinesias

US 09987242	Surmeier et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Dalton James Surmeier (Evanston, Illinois); Weixing Shen (Wilmette, Illinois); Zhong Xie (North Riverside, Illinois)
ABSTRACT	Provided herein are compositions and methods for the treatment and prevention of levodopa-induced dyskinesias (LID). In particular, M4 muscarinic receptor (M4R) positive allosteric modulators (PAMs) are administered to reduce dyskinetic behavior.
FILED	Thursday, May 05, 2016
APPL NO	15/147092
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 31/4365 (20130101) A61K 31/4365 (20130101) A61K 31/5025 (20130101) A61K 31/5025 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09987243 — Use of trans-palmitoleate in identifying and treating metabolic disease

US 09987243	Mozaffarian et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	Dariush Mozaffarian (Boston, Massachusetts); Haiming Cao (Bethesda, Maryland); Gokhan S. Hotamisligil (Wellesley, Massachusetts)
ABSTRACT	The present invention provides for a novel lipokine, trans-C16:1n7-palmitoleate, which also serves as a biomarker for metabolic status. More specifically, low concentrations of trans-C16:1n7-palmitoleate the serum indicates a risk of metabolic disease. Additionally, administering trans C16:1n7-palmitoleate to a subject (via pharmaceutical, nutraceutical, or other means), positively impacts glucose metabolism.
FILED	Friday, August 26, 2016
APPL NO	15/248310
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/12 (20160801) A23L 33/40 (20160801) A23L 33/115 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) A61K 31/201 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 57/03 (20130101)
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09987258 — Histone deacetylase as a modulator of PDL1 expression and activity

US 09987258	Villagra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
ASSIGNEE(S)	H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida)
INVENTOR(S)	Alejandro V. Villagra (Tampa, Florida); Eduardo M. Sotomayor (Tampa, Florida)
ABSTRACT	Disclosed herein is a method for modulating Program Death Receptor Ligand 1 (PDL1) in a cancer cell, comprising contacting the cell with a composition comprising a histone deacetylase (HDAC) inhibitor. Also disclosed is a method for treating a tumor in a subject, comprising administering to the subject a therapeutically effective amount of a composition comprising a histone deacetylase (HDAC) inhibitor and a composition comprising a therapeutically effective amount of a Program Death Receptor Ligand 1 (PDL1) inhibitor, a Programmed Death 1 receptor (PD1) inhibitor, or a combination thereof.
FILED	Monday, April 06, 2015
APPL NO	15/120065
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/416 (20130101) A61K 31/422 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4045 (20130101) A61K 31/4406 (20130101) A61K 45/06 (20130101)
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09987261 — Substituted diazaspiroalkanes as androgen receptor modulators

US 09987261	Jung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Michael E. Jung (Los Angeles, California); Charles L. Sawyers (New York, New York); Samedy Ouk (Los Angeles, California); Chris Tran (New York, New York); John Wongvipat (New York, New York)
ABSTRACT	Described herein, inter alia, are compounds useful for the prevention or treatment of hyperproliferative diseases or disorders.
FILED	Monday, June 13, 2016
APPL NO	15/181030
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/48 (20130101) A61K 31/4439 (20130101) Original (OR) Class Heterocyclic Compounds C07D 401/04 (20130101)
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09987265 — Methods for treating post traumatic stress disorder

US 09987265	Brownstein
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Azevan Pharmaceuticals, Inc. (Bethlehem, Pennsylvania)
ASSIGNEE(S)	AZEVAN PHARMACEUTICALS, INC. (Bethlehem, Pennsylvania)
INVENTOR(S)	Michael J. Brownstein (Rockville, Maryland)
ABSTRACT	Compounds and compositions are described herein for treating post traumatic stress disorder.
FILED	Thursday, April 21, 2016
APPL NO	15/134549
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/397 (20130101) A61K 31/422 (20130101) A61K 31/439 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/4178 (20130101) A61K 31/4545 (20130101) Original (OR) Class A61K 31/5377 (20130101) Heterocyclic Compounds C07D 413/04 (20130101) C07D 413/14 (20130101)
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09987275 — Targeting PARP1 for treatment of TSC and cancers

US 09987275	Lee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Po-Shun Lee (Boston, Massachusetts); Jane Yu (Boston, Massachusetts); Yang Sun (Boston, Massachusetts)
ABSTRACT	The present invention relates to methods of treating a condition associated with mTORC1 hyperactivation or TSC2-deficient cancer, the method comprising administering to a subject having the cancer a pharmaceutically-effective amount of a poly(ADP-ribose) polymerase 1 (PARP1) inhibitor. In some embodiments, the condition associated with mTORC1 hyperactivation is tuberous sclerosis complex (TSC). In some embodiments, the condition associated with mTORC1 hyperactivation is lymphangioleiomyomatosis (LAM). In some embodiments, the condition associated with mTORC1 hyperactivation is TSC2-deficient cancer.
FILED	Thursday, April 23, 2015
APPL NO	15/305883
ART UNIT	1674 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/502 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/713 (20130101) A61K 31/4725 (20130101) A61K 31/4985 (20130101) A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) Enzymes C12Y 204/0203 (20130101)
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09987280 — SIRT1 inhibitors and stem cell rejuvenation

US 09987280	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	City of Hope (Duarte, California)
ASSIGNEE(S)	City of Hope (Duarte, California)
INVENTOR(S)	WenYong Chen (Temple, California); Zhiqiang Wang (Covina, California)
ABSTRACT	Provided herein are, inter alia, methods and compositions for treating or preventing diseases using SIRT1 inhibitors. The methods provided herein are particularly useful for treating or preventing age-related hematological diseases as well as cancerous hematological diseases. Further provided herein are hematopoietic cells useful for treating or preventing hematological diseases.
FILED	Monday, August 11, 2014
APPL NO	14/456484
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/513 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 2035/124 (20130101)
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09987286 — Compositions and methods for the treatment of addiction, psychiatric disorders, and neurodegenerative disease

US 09987286	Goeders et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) U.S. Public Health Service (USPHS)
APPLICANT(S)	Embera NeuroTherapeutics, Inc. (Sudbury, Massachusetts); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)	EMBERA NEUROTHERAPEUTICS, INC. (Sudbury, Massachusetts); BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY and AGRICULTURAL and MECHANICAL COLLEGE (Baton Rouge, Louisiana)
INVENTOR(S)	Nicholas E. Goeders (Shreveport, Louisiana); Barbara S. Fox (Wayland, Massachusetts); Glenn Guerin (Shreveport, Louisiana)
ABSTRACT	The present invention features, inter alia, pharmaceutically acceptable compositions that include metyrapol as the sole pharmaceutically active agent; compositions that include metyrapol and at least one additional pharmaceutically active agent; compositions in which the agent targeting the HPA axis is, itself, new or modified (e.g., a bi-specific antibody designed to traverse the blood-brain barrier or a known compound redesigned by, for example, conjugation to a substance that traverses the blood-brain barrier); and compositions in which the agent targeting the HPA axis is newly formulated in such a way that it fails to significantly inhibit cortisol production in the adrenal gland. For example, the composition can be formulated to include a dosage that is too low to reduce plasma cortisol levels or formulated to preferentially affect the skin.
FILED	Thursday, June 11, 2015
APPL NO	14/736619
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/55 (20130101) A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/5513 (20130101) Original (OR) Class A61K 31/5513 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09987294 — Mitochondria-targeted anti-tumor agents

US 09987294	Altieri et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Dario C. Altieri (Worcester, Massachusetts); Byoung Heon Kang (Shrewsbury, Massachusetts)
ABSTRACT	Described are mitochondria-targeted anti-tumor agents, and methods of making and using the same for the treatment of disorders associated with unwanted cell proliferation.
FILED	Tuesday, March 15, 2016
APPL NO	15/070657
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) Original (OR) Class A61K 47/48023 (20130101) A61K 47/48092 (20130101) A61K 47/48192 (20130101) A61K 47/48315 (20130101) Heterocyclic Compounds C07D 225/06 (20130101)
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09987299 — Methods of improving RNAi in well-differentiated airway epithelia

US 09987299	McCray, Jr. et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S)	University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S)	Paul B. McCray, Jr. (Iowa City, Iowa); Beverly L. Davidson (Iowa City, Iowa); Michael A. Apicella (Iowa City, Iowa); Sateesh Krishnamurthy (Iowa City, Iowa)
ABSTRACT	The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a facilitating agent followed by contacting the cell with a therapeutic RNAi agent, wherein the facilitating agent comprises a Platelet-activating factor receptor (PAFR) ligand.
FILED	Monday, May 04, 2015
APPL NO	14/703536
ART UNIT	1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/685 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 31/715 (20130101) A61K 31/7024 (20130101) A61K 31/7024 (20130101) A61K 31/7032 (20130101) A61K 31/7032 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09987302 — Methods of treating DNA damage

US 09987302	Otterbein
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Leo E. Otterbein (Beverly, Massachusetts)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S)	Leo E. Otterbein (Beverly, Massachusetts)
ABSTRACT	The present invention relates to methods and compositions of treating patients suffering from, or at risk for, DNA damage and to increase life span, i.e., prevent or slow the aging process in all species. The treatment includes administering to the patient a pharmaceutical composition that includes carbon monoxide.
FILED	Wednesday, August 08, 2012
APPL NO	14/236756
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 2005/1094 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2270/0421 (20130101)
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09987308 — Method and compositions for cellular immunotherapy

US 09987308	Riddell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Stanley R. Riddell (Sammamish, Washington); Michael Hudecek (Leipzig, Germany)
ASSIGNEE(S)	Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S)	Stanley R. Riddell (Sammamish, Washington); Michael Hudecek (Leipzig, Germany)
ABSTRACT	The present invention provides methods and compositions to confer and/or augment immune responses mediated by cellular immunotherapy, such as by adoptively transferring genetically modified tumor specific CD8+ T cells in the presence of tumor-specific, subset specific genetically modified CD4+ T cells, wherein the CD4+ T cells confer and/or augment a CD8+ T cells ability to sustain anti-tumor reactivity and increase and/or maximize tumor-specific proliferation of the tumor-specific CD8+ T cells of interest. Pharmaceutical formulations produced by the method, and methods of using the same, are also described.
FILED	Friday, March 23, 2012
APPL NO	14/006641
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 2035/122 (20130101) A61K 2035/124 (20130101) A61K 2039/57 (20130101) A61K 2039/572 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/28 (20130101) C07K 16/2803 (20130101) C07K 16/3061 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/515 (20130101) C12N 2510/00 (20130101)
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09987309 — Direct reprogramming of cells to cardiac myocyte fate

US 09987309	Dzau et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Victor J. Dzau (Durham, North Carolina); Maria Mirotsou (Durham, North Carolina); Tilanthi Jayawardena (Durham, North Carolina)
ASSIGNEE(S)	DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S)	Victor J. Dzau (Durham, North Carolina); Maria Mirotsou (Durham, North Carolina); Tilanthi Jayawardena (Durham, North Carolina)
ABSTRACT	A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
FILED	Friday, July 08, 2011
APPL NO	13/808311
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/33 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/3804 (20130101) A61L 27/3839 (20130101) A61L 29/16 (20130101) A61L 31/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) C12N 2501/65 (20130101) C12N 2501/999 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101)
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09987329 — Methods for treating peripheral nerve damage

US 09987329	Rosenblatt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	Mark Rosenblatt (New York, New York); Victor H. Guaiquil (Bronx, New York); Zan Pan (New York, New York); Natalia Karagianni (New York, New York)
ABSTRACT	VEGF-B, as well as a combination of VEGF-B and VEGF-A, mediates peripheral nerve repair. Methods to treat damage to the peripheral nervous system are described.
FILED	Thursday, March 12, 2015
APPL NO	15/124986
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/1866 (20130101) Original (OR) Class
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09987330 — Methods of treating or preventing pruritis by blocking natriuretic polypeptide B

US 09987330	Hoon et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Mark A. Hoon (Kensington, Maryland); Santosh K. Mishra (Rockville, Maryland)
ABSTRACT	Disclosed is a method of treating, reducing, or preventing pruritis in a mammal, the method comprising administering at least one natriuretic polypeptide b (Nppb) blocking agent to a mammal in an amount effective to treat or prevent pruritis in the mammal. An in vitro method of identifying a compound that inhibits Nppb activity is also disclosed.
FILED	Thursday, December 04, 2014
APPL NO	15/039982
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/052 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/035 (20130101) A01K 2267/0393 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/22 (20130101) Original (OR) Class A61K 38/164 (20130101) A61K 38/1796 (20130101) A61K 38/2242 (20130101) A61K 45/06 (20130101) A61K 47/62 (20170801) Peptides C07K 16/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) C12N 15/8509 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/02 (20130101)
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09987331 — Treating cardiovascular or renal diseases

US 09987331	Ikeda et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Yasuhiro Ikeda (Rochester, Minnesota); Stephen James Russell (Rochester, Minnesota); Alessandro Cataliotti (Rochester, Minnesota); John C. Burnett, Jr. (Rochester, Minnesota); Jason M. Tonne (Rochester, Minnesota)
ABSTRACT	This document provides methods and materials for treating cardiovascular and/or renal diseases. For example, AAV9 vectors designed to express natriuretic polypeptides, nucleic acid molecules encoding natriuretic polypeptides, methods for making AAV9 vectors, and methods for using such vectors or molecules to treat cardiovascular and/or renal diseases are provided.
FILED	Friday, February 17, 2017
APPL NO	15/436426
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/2242 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101)
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09987336 — Attenuating or treating sepsis or septic shock

US 09987336	Hasko et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Rutgers, the State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Gyorgy Hasko (Gillette, New Jersey); Zoltan Nemeth (Randolph, New Jersey)
ABSTRACT	Methods for attenuating or treating, or reducing the mortality of sepsis or septic shock using an ectonucleotidase such as CD39 or CD73 are provided.
FILED	Friday, August 09, 2013
APPL NO	14/420462
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/46 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 45/06 (20130101) Enzymes C12Y 301/03005 (20130101) C12Y 306/01005 (20130101)
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09987343 — Haemophilus influenzae type IV pili

US 09987343	Bakaletz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	NATIONWIDE CHILDREN'S HOSPITAL, INC. (Columbus, Ohio)
ASSIGNEE(S)	NATIONWIDE CHILDREN'S HOSPITAL, INC. (Columbus, Ohio)
INVENTOR(S)	Lauren O. Bakaletz (Hilliard, Ohio); Robert S. Munson, Jr. (Columbus, Ohio)
ABSTRACT	The invention described herein relates to a Haemophilus influenzae (H. influenzae) regulon encoding type IV pili. In particular, the invention relates to type IV pili from nontypeable H. influenzae (NTHi) and from H. influenzae strains a, b, c, e and f. The invention provides isolated H. influenzae pilus polynucleotides and polypeptides encoded by the polynucleotides as well as polynucleotides and polypeptides encoded by the polynucleotides involved in the assembly/disassembly of the structure. The invention also relates to uses of these polynucleotides and/or polypeptides including methods for eliciting an immune response to H. influenzae and methods of treating and preventing H. influenzae related pathological conditions.
FILED	Wednesday, December 21, 2016
APPL NO	15/387055
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/102 (20130101) Original (OR) Class Peptides C07K 14/285 (20130101) C07K 16/1242 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101)
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09987346 — Methods and compositions for vaccinating a subject for a sexually transmitted pathogen

US 09987346	Massari et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Tufts University (Boston, Massachusetts); Boston Medical Center Corporation (Boston, Massachusetts); The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts); Boston Medical Center Corporation (Boston, Massachusetts); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Paola Massari (Cambridge, Massachusetts); Guillermo Madico (Natick, Massachusetts); Luis de la Maza (Irvine, California)
ABSTRACT	Purified Chlamydia major outer membrane protein (MOMP) has been observed to induce protection against genital and respiratory challenge in mice. MOMP contains variable domains that are highly immunogenic and elicit cross-serovar neutralizing monoclonal and polyclonal antibodies and T cell responses in animal and human models. Examples herein provide a method for vaccinating a subject against Chlamydia using a composition that is a recombinant Neisseria porin that contains at least one antigenic variable domain of Chlamydia. The variable domains are inserted into the amino acid sequence of the Neisseria porin at a position encoding a surface-exposed loop of the Neisseria porin. The vaccine further contains an adjuvant that induces a Th1 response greater than a Th2 response.
FILED	Friday, March 03, 2017
APPL NO	15/448767
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/118 (20130101) Original (OR) Class A61K 2039/575 (20130101) A61K 2039/6068 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/22 (20130101) C07K 14/295 (20130101)
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09987353 — Virus like vesicles (VLVS) based vaccines to prevent or treat chronic hepatitis B virus (HBV) infection

US 09987353	Robek et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	YALE UNIVERSITY (New Haven, Connecticut); Sandra E. Osborne (Granbury, Texas)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Michael Robek (Slingerlands, New York); John Rose (Guilford, Connecticut); Tracy Reynolds (New Haven, Connecticut)
ABSTRACT	The present invention relates to the discovery of compositions and methods for therapeutic immunization for treatment of chronic hepatitis B. Methods of the invention include a method generating an evolved high titer hybrid-hepatitis B virus (HBV) vector, methods of treating and/or preventing HBV, and methods of inducing a memory T and B cell immune response against HBV infection in a subject administered the VLV composition produced thereby. Furthermore, the invention encompasses a pharmaceutical composition for vaccinating a subject to protect the subject against infection with HBV.
FILED	Monday, May 11, 2015
APPL NO	15/305180
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/292 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2730/10134 (20130101) C12N 2730/10143 (20130101) C12N 2770/36143 (20130101) C12N 2810/6081 (20130101)
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09987355 — Vaccine composition containing synthetic adjuvant

US 09987355	Reed et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Infectious Disease Research Institute (Seattle, Washington)
ASSIGNEE(S)	Infectious Disease Research Institute (Seattle, Washington)
INVENTOR(S)	Steven G. Reed (Bellevue, Washington); Darrick Carter (Seattle, Washington)
ABSTRACT	Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogeneous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier.
FILED	Friday, June 28, 2013
APPL NO	13/930953
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 39/04 (20130101) A61K 39/008 (20130101) A61K 39/0011 (20130101) A61K 39/35 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 45/06 (20130101) A61K 2039/55511 (20130101) A61K 2039/55572 (20130101)
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09987356 — Anti-CD40 antibodies and methods of administering thereof

US 09987356	Reimann et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Keith A. Reimann (Marblehead, Massachusetts); Rijian Wang (Saugus, Massachusetts); Christian P. Larsen (Atlanta, Georgia)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Emory University (Atlanta, Georgia)
INVENTOR(S)	Keith A. Reimann (Marblehead, Massachusetts); Rijian Wang (Saugus, Massachusetts); Christian P. Larsen (Atlanta, Georgia)
ABSTRACT	The present invention relates to antibodies specific for a particular epitope on CD40 and antibodies that bind CD40 and have particular functional characteristics. The present invention also relates to fragments of these antibodies, uses of the antibodies for reduction or treatment of transplant rejection and graft-versus-host disease, and methods for making the antibodies.
FILED	Monday, March 12, 2012
APPL NO	14/004552
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 38/13 (20130101) A61K 38/13 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 39/39541 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/18 (20130101) C07K 16/2866 (20130101) C07K 16/2875 (20130101) C07K 16/2878 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101)
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09987358 — Nanostars and nanoconstructs for detection, imaging, and therapy

US 09987358	Vo-Dinh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Tuan Vo-Dinh (Chapel Hill, North Carolina); Hsiangkuo Yuan (Chalfont, Pennsylvania); Andrew Fales (Duham, North Carolina); Christopher Khoury (Durham, North Carolina)
ABSTRACT	A polymer-free synthesis method is provided for preparation of monodisperse nanostars. The nanostars can be used for treating and imaging cells in in vivo or ex vivo. The modes of treatment include use of a nanostar modified with a photo-activatable drug, which drug is activated by the photo-response of the nanostar to electromagnetic stimulation; use of a nanostar modified with a thermally-activatable drug, which drug is activated by a thermal response of the nanostar to electromagnetic stimulation; and the thermal response of the nanostar itself to electromagnetic stimulation, which can directly or indirectly cause the death of an undesirable cell.
FILED	Wednesday, January 18, 2017
APPL NO	15/408563
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) Original (OR) Class A61K 49/1821 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101)
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09987371 — Compositions and methods for polynucleotide transfection

US 09987371	Wickline et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Washington University (St. Louis, Missouri)
ASSIGNEE(S)	WASHINGTON UNIVERSITY (Saint Louis, Missouri)
INVENTOR(S)	Samuel A. Wickline (St. Louis, Missouri); Kirk Hou (St. Louis, Missouri)
ABSTRACT	A pharmaceutical composition comprising a peptide-polynucleotide complex, and methods of use thereof.
FILED	Thursday, July 02, 2015
APPL NO	14/790408
ART UNIT	1676 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 38/00 (20130101) A61K 47/42 (20130101) A61K 47/6455 (20170801) A61K 47/48323 (20130101) Original (OR) Class Peptides C07K 19/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3513 (20130101) C12N 2320/32 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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09987379 — Molecular probes for imaging of myelin

US 09987379	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Yanming Wang (Beachwood, Ohio); Chunying Wu (Mayfield Heights, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Yanming Wang (Beachwood, Ohio); Chunying Wu (Mayfield Heights, Ohio)
ABSTRACT	A molecular probe for labeling myelin includes a fluorescent trans-stilbene derivative.
FILED	Wednesday, September 30, 2009
APPL NO	13/121742
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/10 (20130101) A61K 49/0021 (20130101) A61K 49/0032 (20130101) A61K 49/0052 (20130101) A61K 49/085 (20130101) Original (OR) Class A61K 51/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 2405/10 (20130101) G01N 2800/285 (20130101)
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09987380 — Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same

US 09987380	Li et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Zibo Li (San Gabriel, California); Francois P. Gabbai (College Station, Texas); Peter S. Conti (Pasadena, California); Todd W. Hudnall (College Station, Texas); Tzu-Pin Lin (College Station, Texas); Shuanglong Liu (Alhambra, California); Chiun-Wei Huang (Alhambra, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Zibo Li (San Gabriel, California); Francois P. Gabbai (College Station, Texas); Peter S. Conti (Pasadena, California); Todd W. Hudnall (College Station, Texas); Tzu-Pin Lin (College Station, Texas); Shuanglong Liu (Alhambra, California); Chiun-Wei Huang (Alhambra, California)
ABSTRACT	A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof: wherein R₁-R₇may be independently selected from hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, X is selected from the group consisting of C and N; and A is selected of hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, alkyl, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, including phenyl and aminophenyl, and heteroaryl.
FILED	Friday, July 13, 2012
APPL NO	13/549309
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/0021 (20130101) A61K 51/00 (20130101) A61K 51/0423 (20130101) A61K 51/0446 (20130101) Original (OR) Class A61K 51/0455 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101)
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09987468 — Reduced force device for intravascular access and guidewire placement

US 09987468	Bagwell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	Actuated Medical, Inc. (Bellefonte, Pennsylvania)
ASSIGNEE(S)	Actuated Medical, Inc. (Bellefonte, Pennsylvania)
INVENTOR(S)	Roger B Bagwell (Bellefonte, Pennsylvania); Ryan S Clement (State College, Pennsylvania); Maureen L Mulvihill (Bellefonte, Pennsylvania); Casey A Scruggs (Middleburg, Pennsylvania); Kevin A Snook (State College, Pennsylvania)
ABSTRACT	A device for penetrating tissue with reduced force and placing a guidewire is provided. The device includes a driving actuator generating reciprocating motion. A penetrating member having a lumen dimensioned to accommodate a guidewire is provided. A coupler mechanically connects the driving actuator and the penetrating member to transfer the reciprocating motion to the penetrating member. The penetrating member may be coaxial or axially offset from the driving actuator. At least one frictional member facilitates the movement of the guidewire through the lumen for placement at the target tissue. The frictional member(s) may be operated manually or by a guidewire actuator. A housing may also be provided including a channel also dimensioned to accommodate the guidewire, and may further include the frictional member(s) for facilitating movement of the guidewire. The channel and lumen are aligned to permit placement of the guidewire at the target site.
FILED	Friday, July 08, 2016
APPL NO	15/205357
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/15003 (20130101) A61B 5/150137 (20130101) A61B 5/150389 (20130101) A61B 10/025 (20130101) A61B 10/0233 (20130101) A61B 17/3401 (20130101) A61B 17/3415 (20130101) A61B 17/3476 (20130101) A61B 17/320068 (20130101) A61B 2010/0208 (20130101) A61B 2017/00115 (20130101) A61B 2017/00123 (20130101) A61B 2090/064 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/3287 (20130101) A61M 25/06 (20130101) A61M 25/0084 (20130101) A61M 25/09041 (20130101) Original (OR) Class A61M 2025/09116 (20130101)
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09987505 — Method for modifying glomerular permeability and function with focused ultrasound

US 09987505	Jolesz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Ferenc Jolesz (Brookline, Massachusetts); Krisztina Fischer (Brookline, Massachusetts); Nathan McDannold (Boston, Massachusetts)
ASSIGNEE(S)	The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Ferenc Jolesz (Brookline, Massachusetts); Krisztina Fischer (Brookline, Massachusetts); Nathan McDannold (Boston, Massachusetts)
ABSTRACT	A method for noninvasively changing the permeability of a region of a subject that includes a desired tissue is provided. More specifically, low-power focused ultrasound (FUS) is employed to alter the permeability of the glomerulus so as to alter the glomerular ultrafiltration coefficient. By employing FUS after administering a microbubble contrast agent to a subject, glomerular filtration is temporarily increased and the clearance of larger molecules, which are normally not filtered by the kidney, is allowed. This method offers new treatment opportunities for renal disease management.
FILED	Thursday, August 20, 2009
APPL NO	13/058945
ART UNIT	3777 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 2090/374 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101)
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09988341 — Bacterial topoisomerase inhibitors and use thereof

US 09988341	Tse-Dinh et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Yuk-Ching Tse-Dinh (Coral Gables, Florida); Marcello Angelo Giulianotti (Vero Beach, Florida); Richard Allen Houghten (Port St. Lucie, Florida)
ASSIGNEE(S)	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida); TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (Port St. Lucie, Florida)
INVENTOR(S)	Yuk-Ching Tse-Dinh (Coral Gables, Florida); Marcello Angelo Giulianotti (Vero Beach, Florida); Richard Allen Houghten (Port St. Lucie, Florida)
ABSTRACT	The present invention provides novel compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
FILED	Wednesday, April 19, 2017
APPL NO	15/491679
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 211/30 (20130101) Original (OR) Class
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09988343 — Inhibitors of histone deacetylase

US 09988343	Mazitschek et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Ralph Mazitschek (Belmont, Massachusetts); Teru Hideshima (Brookline, Massachusetts); Kenneth C. Anderson (Wellesley, Massachusetts); Stephen J. Haggarty (Gloucester, Massachusetts); Balaram Ghosh (Hyderabad, India)
ABSTRACT	The present invention relates to compounds which inhibit histone deacetylase activity and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing these compounds. The present invention also relates to methods of treating and preventing hematological cell proliferative disorders, such as multiple myeloma, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
FILED	Wednesday, November 05, 2014
APPL NO	15/034276
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/455 (20130101) A61K 31/455 (20130101) A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/4402 (20130101) A61K 31/4402 (20130101) A61K 31/4406 (20130101) A61K 31/4409 (20130101) A61K 31/4409 (20130101) A61K 31/4965 (20130101) A61K 31/4965 (20130101) A61K 38/05 (20130101) A61K 38/05 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 237/40 (20130101) Original (OR) Class C07C 237/42 (20130101) Heterocyclic Compounds C07D 213/81 (20130101) C07D 213/82 (20130101) C07D 239/42 (20130101) C07D 241/24 (20130101)
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09988371 — Benzimidazole analogues and related methods

US 09988371	Li et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Arizona Board of Regents, on Behalf of the University of Arizona (Tucson, Arizona); Universita' Federico II (Naples, Italy)
ASSIGNEE(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); UNIVERSITA' FEDERICO II (, Italy)
INVENTOR(S)	Hong-yu Li (Tucson, Arizona); Brendan Frett (Tucson, Arizona); Massimo Santoro (Naples, Italy); Francesca Carlomagno (Naples, Italy)
ABSTRACT	The invention relates to compounds of the formula (VIII) wherein the moieties R₁, R₂, R₃, R₄, and R₅are as defined in the specification, and salts thereof, as well as their use, methods of use for them, methods of their synthesis, and the like. The compounds are protein tyrosine kinase inhibitors and can be used in the treatment of various cancer diseases and cancer-associated pain.
FILED	Wednesday, June 03, 2015
APPL NO	15/315490
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/422 (20130101) A61K 31/506 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 413/12 (20130101) C07D 413/14 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Enzymes C12Y 207/10002 (20130101)
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09988374 — Cytochrome P450 inhibitors and uses thereof

US 09988374	Panicker
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	ANGION BIOMEDICA CORP. (Uniondale, New York)
ASSIGNEE(S)	ANGION BIOMEDICA CORP. (Uniondale, New York)
INVENTOR(S)	Bijoy Panicker (Holtsville, New York)
ABSTRACT	The present invention provides compounds having the general structural formula (I) (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.
FILED	Tuesday, August 11, 2015
APPL NO	15/503267
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) Heterocyclic Compounds C07D 417/06 (20130101) Original (OR) Class
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09988407 — Prodrugs of prostate specific membrane antigen (PSMA) inhibitor

US 09988407	Slusher et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR v.v.i. (Prague, Czech Republic)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR V.V.I. (Prague, Czech Republic)
INVENTOR(S)	Barbara Slusher (Kingsville, Maryland); Rana Rais (West Firendship, Maryland); Marcela Krecmerova (Prague, Czech Republic); Tomas Tichy (Prague, Czech Republic); Pavel Majer (Sykesville, Maryland); Andrej Jancarik (Koprivnice, Czech Republic)
ABSTRACT	Methods and compounds are disclosed for treating a disease or condition by inhibiting PSMA (Prostate Specific Membrane Antigen) using prodrugs of 2-PMPA.
FILED	Thursday, August 06, 2015
APPL NO	15/502105
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/3808 (20130101) C07F 9/4075 (20130101) C07F 9/4084 (20130101) C07F 9/4087 (20130101) C07F 9/4465 (20130101) C07F 9/65586 (20130101) Original (OR) Class
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09988424 — Immunogens comprising human immunodeficiency virus V1/V2 polypeptides

US 09988424	Haynes et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center (VRC)
APPLICANT(S)	DUKE UNIVERSITY (Durham, North Carolina); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia); NEW YORK UNIVERSITY (New York, New York)
ASSIGNEE(S)	DUKE UNIVERSITY (Durham, North Carolina); U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (Fort Detrick, Maryland); NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S)	Barton F. Haynes (Durham, North Carolina); Huaxin Liao (Durham, North Carolina); Jerome Kim (Fort Detrick, Maryland); Nelson Michael (Fort Detrick, Maryland); Susan B. Zolla-Pazner (New York, New York)
ABSTRACT	The invention is generally directed to V1V2 immunogens.
FILED	Wednesday, December 05, 2012
APPL NO	14/363131
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/162 (20130101) C07K 16/1063 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24043 (20130101) C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101)
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09988434 — Optimal interstrand bridge for collagen mimics

US 09988434	Raines et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Ronald T. Raines (Madison, Wisconsin); Ismet C. Tanrikulu (Madison, Wisconsin)
ABSTRACT	Novel collagen-mimetic peptides are disclosed comprising the formula (Xaa-Yaa-Gly)_n, where the amino acid at one of the Xaa positions is substituted with a homocysteine residue. Also disclosed are multi-stranded novel collagen-mimetic peptides comprising a first strand as described above that is covalently bonded with a disulfide bridge to a second strand comprising the formula (Xaa-Yaa-Gly)_m, where the amino acid at one of the Yaa positions is substituted with a cysteine residue. Disulfide formation between the terminal thiol sulfur of the homocysteine residue of the first strand and the terminal thiol sulfur of the cysteine residue of the second strand reveals unstrained bridges that enhance the structure and substantially improve the stability of collagen triple helices as compared to other possible disulfide or thioether bridges. Thus, the disclosed collagen mimetic peptides have improved stability, and can be used to produce optimized collagen-like fibrillar assemblies for wound healing and other biomedical applications.
FILED	Friday, September 11, 2015
APPL NO	14/852011
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/0033 (20130101) A61L 26/0066 (20130101) Peptides C07K 14/78 (20130101) Original (OR) Class
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09988612 — T7 RNA polymerase variants with expanded substrate range and enhanced transcriptional yield

US 09988612	Ellington et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Andrew D. Ellington (Austin, Texas); Adam J. Meyer (Austin, Texas)
ABSTRACT	Disclosed are T7 RNA polymerase variants with enhanced transcriptional activity. T7 RNA polymerase variants are known which have the ability to incorporate modified ribonucleotides into growing RNA molecules. However, these variants have relatively low levels of transcriptional activity. Presented herein are mutations that increase the transcriptional activity of the variants with broad substrate range.
FILED	Friday, March 20, 2015
APPL NO	15/127617
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1247 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2320/51 (20130101) C12N 2330/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 207/07006 (20130101)
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09988623 — Methods of X-aptamer generation and compositions thereof

US 09988623	Gorenstein et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Child Health and Human Development (NICHD) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Board of Regents of the University of Texas System (Austin, Texas); AM Biotechnologies, LLC (Houston, Texas)
ASSIGNEE(S)	AM Biotechnologies, LLC (Houston, Texas); Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	David G Gorenstein (Houston, Texas); Weiguo He (Pearland, Texas); David E Volk (Dickinson, Texas); Miguel-Angel Elizondo-Riojas (Houston, Texas); Ross Durland (The Woodlands, Texas); Johnnie Engelhardt (West Columbia, Texas)
ABSTRACT	Provided herein are methods for a novel bead-based next-generation “X-aptamer” selection scheme that extends aptamer technology to include X-modified bases, thus resulting in X-aptamers, at any position along the sequence because the aptamers are chemically synthesized via a split-pool scheme on individual beads. Also provides are application to a wide range of commonly used DNA modifications, including, but not limited to, monothioate and dithioate backbone substitutions. This new class of aptamer allows chemical modifications introduced to any of the bases in the aptamer sequence as well as the phosphate backbones and can be extended to other carbohydrate-based systems.
FILED	Thursday, October 10, 2013
APPL NO	14/051363
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1048 (20130101) C12N 15/1058 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/315 (20130101) C12N 2310/351 (20130101) C12N 2320/11 (20130101) C12N 2330/31 (20130101)
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09988630 — Methods and compositions for the specific inhibition of gene expression by double-stranded RNA

US 09988630	Rossi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	CITY OF HOPE (Duarte, California); INTEGRATED DNA TECHNOLOGIES, INC. (Coralville, Iowa)
ASSIGNEE(S)	City of Hope (Duarte, California); Integrated DNA Technologies, Inc. (Coralville, Iowa)
INVENTOR(S)	John J. Rossi (Alta Loma, California); Mark A. Behlke (Coralville, Iowa); Dongho Kim (Los Angeles, California)
ABSTRACT	The invention provides compositions and methods for selectively reducing the expression of a gene product from a desired target gene, as well as treating diseases caused by expression of the gene. The method involves introducing into the environment of a cell an amount of a double-stranded RNA (dsRNA) such that a sufficient portion of the dsRNA can enter the cytoplasm of the cell to cause a reduction in the expression of the target gene. The dsRNA has a first oligonucleotide sequence that is between 26 and about 30 nucleotides in length and a second oligonucleotide sequence that anneals to the first sequence under biological conditions. In addition, a region of one of the sequences of the dsRNA having a sequence length of from about 19 to about 23 nucleotides is complementary to a nucleotide sequence of the RNA produced from the target gene.
FILED	Monday, June 13, 2016
APPL NO	15/181162
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/33 (20130101) C12N 2310/51 (20130101) C12N 2320/30 (20130101) C12N 2320/50 (20130101) C12N 2320/51 (20130101) C12N 2330/30 (20130101)
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09988631 — Pharmaceutical composition comprising Nanog shRNA, and method of using Nanog shRNA to treat cancer

US 09988631	Jessup et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	John Milburn Jessup (Potomac, Maryland); Nikolay Korokhov (Germantown, Maryland)
ABSTRACT	The present description relates to an inhibitory RNA molecule, comprising an oligonucleotide that selectively knocks down expression a Nanog pseudogene expressed in many human cancers, a replicating viral vector capable of encoding such inhibitory RNA molecule, pharmaceutical compositions comprising said vector, and methods of treating cancer by administration of said pharmaceutical composition.
FILED	Wednesday, October 26, 2016
APPL NO	15/334666
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/32 (20130101) C12N 2710/10032 (20130101) C12N 2710/10043 (20130101) C12N 2710/10045 (20130101) C12N 2799/022 (20130101) C12N 2799/028 (20130101) C12N 2820/007 (20130101) C12N 2830/008 (20130101)
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09988633 — Compositions and methods to promote erythropoiesis

US 09988633	Bresnick et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Emery H. Bresnick (Middleton, Wisconsin); Yoon A. Kang (San Francisco, California); Skye McIver (Madison, Wisconsin)
ABSTRACT	Described herein are compositions and methods for enhancing erythropoiesis in an individual in need thereof. Specifically agents that decrease the expression of Exosc10, such as inhibitory nucleic acid molecules, produce an increase in red blood cell production in the individual.
FILED	Wednesday, August 16, 2017
APPL NO	15/678362
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/14 (20130101) C12N 2310/15 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) Enzymes C12Y 301/13 (20130101)
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09988665 — Methods for determining protein binding specificity using peptide libraries

US 09988665	Denu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	John M. Denu (McFarland, Wisconsin); Adam L. Garske (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	John M. Denu (McFarland, Wisconsin); Adam L. Garske (Madison, Wisconsin)
ABSTRACT	A method for determining protein binding specificity using a screen of a peptide library is provided. The method can be used to determine binding specificity for human NAD⁺-dependent deacetylase SIRT1, and to identify the most efficiently deacetylated peptide sequences. The method can be also used to screen a combinatorial H4 histone N-terminal tail peptide library to examine the binding preferences of a α-phos (S1) H4 antibody toward all known possible H4 histone modification states.
FILED	Friday, August 12, 2011
APPL NO	13/208894
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) Original (OR) Class Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) G01N 2333/98 (20130101)
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09988667 — Device and methods for epigenetic analysis

US 09988667	Craighead et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) National Science Foundation (NSF)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Harold G. Craighead (Ithaca, New York); Benjamin R. Cipriany (Ithaca, New York); Stephen Levy (Ithaca, New York); Paul Soloway (Ithaca, New York)
ABSTRACT	Provided herein are methods and devices for single object detection. The methods and devices can be used to identify a plurality of epigenetic markers on a genetic material, or a chromatin, encompassing fragments thereof. The invention provides for the characterization of the genetic material flowing through a channel in a continuous body of fluid based on detection of one or more properties of the genetic material. The methods and systems provided herein allow genome-wide, high-throughput epigenetic analysis and overcome a variety of limitations common to bulk analysis techniques.
FILED	Friday, August 26, 2016
APPL NO	15/249275
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0663 (20130101) B01L 2300/0654 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2561/113 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101)
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09988674 — Full interrogation of nuclease DSBs and sequencing (find-seq)

US 09988674	Joung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	J. Keith Joung (Winchester, Massachusetts); Shengdar Tsai (Charlestown, Massachusetts)
ABSTRACT	Sensitive, unbiased methods for genome-wide detection of potential off-target nuclease cleavage sites in DNA, e.g., in cell type-specific genomic DNA samples.
FILED	Monday, September 12, 2016
APPL NO	15/262972
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6855 (20130101) Original (OR) Class C12Q 2521/301 (20130101) C12Q 2521/319 (20130101) C12Q 2521/501 (20130101) C12Q 2525/191 (20130101) C12Q 2525/301 (20130101) C12Q 2535/122 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/06 (20130101)
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09988679 — MSP nanopores and related methods

US 09988679	Gundlach et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	University of Washington (Seattle, Washington); The UAB Research Foundation (Birmingham, Alabama)
ASSIGNEE(S)	University of Washington (Seattle, Washington); The UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S)	Jens H. Gundlach (Seattle, Washington); Michael Niederweis (Homewood, Alabama); Thomas Z. Butler (Seattle, Washington); Mikhail Pavlenok (Birmingham, Alabama); Mark A. Troll (Seattle, Washington); Suja Sukumaran (Dublin, California)
ABSTRACT	Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.
FILED	Friday, April 14, 2017
APPL NO	15/488311
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/00 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101)
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09988680 — Non-natural nucleosides as theranostic agents

US 09988680	Berdis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Anthony J. Berdis (Cleveland Heights, Ohio); Irene Lee (Cleveland Heights, Ohio); Edward Motea (Dallas, Texas)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Anthony J. Berdis (Cleveland Heights, Ohio); Irene Lee (Cleveland Heights, Ohio); Edward Motea (Dallas, Texas)
ABSTRACT	A composition for monitoring DNA damage includes a 3-ethynyl-5-nitroindolyl-2′-deoxyribose compound or pharmaceutically acceptable salt thereof and a detectable moiety with a click-reactive functional group that is complementary to the alkyne group of the compound.
FILED	Tuesday, September 04, 2012
APPL NO	14/342502
ART UNIT	1673 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/044 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101)
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09988687 — Companion diagnostics for cancer and screening methods to identify companion diagnostics for cancer based on splicing variants

US 09988687	Lee et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Norman Lee (Dayton, Maryland); Bi-Dar Wang (Potomac, Maryland)
ASSIGNEE(S)	THE GEORGE WASHINGTON UNIVERISTY (, District of Columbia)
INVENTOR(S)	Norman Lee (Dayton, Maryland); Bi-Dar Wang (Potomac, Maryland)
ABSTRACT	A method of classifying a patient for eligibility for cancer therapy based on the presence or absence of splicing variants in a sample of the patient's cancer tissue. Also, a method of screening cancer therapies for efficacy against splicing variants. More specifically, the methods relate to novel splicing variants of genes associated with cancer risk and survival, particularly splicing variants of PIK3CD, FGFR3, TSC2, RASGRP2, ITGA4, MET, NF1 and BAK1. Also more specifically, the methods relate to classifying a patient for eligibility for cancer therapy involving the use of GS-1101.
FILED	Thursday, March 05, 2015
APPL NO	14/639219
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101)
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09989471 — Device for spectroscopic detection and monitoring of biologically relevant molecules

US 09989471	Marks et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF)
APPLICANT(S)	The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	The Texas A and M University System (College Station, Texas)
INVENTOR(S)	Haley L. Marks (Brighton, Massachusetts); Gerard L. Coté (College Station, Texas); Mitchell B. Robinson (Willow Park, Texas); Po-Jung Huang (College Station, Texas); Jun Kameoka (College Station, Texas)
ABSTRACT	There is a need in the point-of-care diagnostic community for an efficient and portable method for testing blood and other biological fluids that can be easily translated across multiple applications. An aspect of the invention described involves monitoring the optical properties of molecularly-mediated nanoparticle assemblies though an optically transparent and magnetically active microfluidic chip, which has recently emerged as an attractive method for biomarker detection as it is an efficient tool for monitoring the binding events that take place in a sensing assay. In one embodiment, this device is directed towards two-nanoparticle assays that rely on the assembly or disassembly of plasmonic and magnetic nanoparticles in response to a certain analyte. A further embodiment is directed to a spiral microfluidic using inertial forces to filter fluid components by size, connected to a magnetically active channel comprised of a nickel micropad array, optically transparent microchannel, and permanent magnets.
FILED	Monday, February 13, 2017
APPL NO	15/431604
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 21/658 (20130101) Original (OR) Class G01N 2021/651 (20130101)
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09989497 — Front end circuitry with analog sampling and decoding for ultrasound imaging systems and methods of use

US 09989497	Walker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	William F. Walker (Earlysville, Virginia); Michael I. Fuller (Williamsburg, Virginia); Karthik Ranganathan (Cambridge, Massachusetts); John A. Hossack (Charlottesville, Virginia); Travis N. Blalock (Charlottesville, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	William F. Walker (Earlysville, Virginia); Michael I. Fuller (Williamsburg, Virginia); Karthik Ranganathan (Cambridge, Massachusetts); John A. Hossack (Charlottesville, Virginia); Travis N. Blalock (Charlottesville, Virginia)
ABSTRACT	Pulse-echo imaging systems and methods are provided, including a transmit code sequencer and a pulse generation circuit, The transmit code sequencer is configured to input a transmit code sequence to the pulse generation circuit. A transducer is configured to receive electrical signals provided as pulses using coded excitation according to the transmit code sequence, and to transduce the electrical signals to pulses of energy other than electrical signals. The transducer is further configured to receive echoes of the pulses of energy other than electrical signals and convert the echoes to received electrical signals generate using coded excitation. A receive circuit is configured to receive the received electrical signals generate using coded excitation, perform analog sampling of the received electrical signals generate using coded excitation, and provide a weighted, summed digital signal by processing the analog samples. At least one example of a pulse imaging system described is configured for ultrasonic pulse-echoes. At least one example of a pulse imaging system described is a medical diagnostic imaging system.
FILED	Tuesday, August 18, 2009
APPL NO	12/543452
ART UNIT	3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 8/00 (20130101) A61B 8/4483 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/0654 (20130101) Original (OR) Class G01N 2291/02475 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52026 (20130101) G01S 7/52046 (20130101) G01S 7/52079 (20130101) G01S 15/8959 (20130101)
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09989515 — Devices with fluidic nanofunnels, associated methods, fabrication and analysis systems

US 09989515	Ramsey et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	John Michael Ramsey (Chapel Hill, North Carolina); Laurent Menard (Cary, North Carolina); Jinsheng Zhou (Chapel Hill, North Carolina); Michael Rubinstein (Chapel Hill, North Carolina); Sergey Panyukov (Moscow, Russian Federation)
ABSTRACT	Methods of forming a chip with fluidic channels include forming (e.g., milling) at least one nanofunnel with a wide end and a narrow end into a planar substrate, the nanofunnel having a length, with width and depth dimensions that both vary over its length and forming (e.g., milling) at least one nanochannel into the planar substrate at an interface adjacent the narrow end of the nanofunnel.
FILED	Thursday, February 07, 2013
APPL NO	14/368971
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502761 (20130101) B01L 2200/0663 (20130101) B01L 2300/0858 (20130101) B01L 2300/0864 (20130101) B01L 2300/0896 (20130101) B01L 2400/0421 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) Original (OR) Class G01N 33/54366 (20130101)
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09989530 — Methods and materials for the detection of dengue virus infection

US 09989530	Raychaudhuri et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	InBios International, Inc. (Seattle, Washington)
ASSIGNEE(S)	InBios International, Inc. (Seattle, Washington)
INVENTOR(S)	Syamal Raychaudhuri (Seattle, Washington); Raymond L. Houghton (Bothell, Washington); Stanislaw Morkowski (Seattle, Washington); Yvonne Stevens (Bellevue, Washington); Mohua Bose (Redmond, Washington); James William Needham (Seattle, Washington); Hongjing Chen (Seattle, Washington)
ABSTRACT	The present invention provides monoclonal antibodies that are specific for the Dengue non-structural glycoprotein NS1 in monomeric and/or oligomeric (primarily dimeric) form, together with methods, including ELISA and lateral flow assays, that employ the disclosed antibodies for the early detection of Dengue virus infection. Diagnostic kits for the detection of Dengue infection are also provided, such kits including the disclosed monoclonal and/or polyclonal antibodies.
FILED	Tuesday, November 22, 2016
APPL NO	15/359421
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/1081 (20130101) C07K 2317/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/558 (20130101) G01N 33/54366 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/185 (20130101)
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09989533 — Anti-TNF induced apoptosis (ATIA) diagnostic markers and therapies

US 09989533	Liu
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Zhenggang Liu (Germantown, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Zhenggang Liu (Germantown, Maryland)
ABSTRACT	The invention features diagnostic and therapeutic methods and compositions featuring Anti-TNF Induced Apoptosis (ATIA). ATIA is useful as a diagnostic marker for cancer, in particular for glioblastoma. ATIA is also a therapeutic target in diseases such as cancer. The invention encompasses combination therapies where knockdown of ATIA is used in combination with other treatment. The invention also features kits for use in the diagnostic and therapeutic methods.
FILED	Thursday, May 27, 2010
APPL NO	13/322863
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/82 (20130101) C07K 14/4747 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) Original (OR) Class G01N 2800/52 (20130101) G01N 2800/56 (20130101)
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09989540 — Diagnostic and monitoring system for Huntington's disease

US 09989540	Potkin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Steven Potkin (Irvine, California); Leslie Thompson (Irvine, California); Zhiqun Tan (Irvine, California); Charles Glabe (Irvine, California)
ABSTRACT	The invention provides assays that identify Huntington's disease and monitor the progression and severity of conditions associated with variant Huntingtin protein (Httn). In particular, the invention provides assays that monitor the severity and progression of Huntington's Disease as well as predict the onset of symptoms. The invention also provides assays for identifying drugs for treating Huntington's disease.
FILED	Friday, May 09, 2014
APPL NO	14/889142
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 2800/52 (20130101) G01N 2800/2835 (20130101)
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09989610 — Multiband slice accelerated imaging with balanced slice-selective gradients

US 09989610	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Siemens Healthcare GmbH (Erlangen, Germany); Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	Siemens Healthcare GmbH (Erlangen, Germany); Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Dingxin Wang (Apple Valley, Minnesota); Vibhas Deshpande (Austin, Texas); Xiufeng Li (Shoreview, Minnesota); Kamil Ugurbil (Minneapolis, Minnesota)
ABSTRACT	A computer-implemented method for performing multi-band slice accelerated imaging includes performing a low-resolution fast multi-dimensional reference scan to obtain a coil sensitivity map. A multiband imaging scan is performed to acquire a plurality of k-space lines representative of an anatomical area of interest. A multi-band signal corresponding to the plurality of k-space lines is separated into a plurality of image slices using a parallel imaging reconstruction technique and the coil sensitivity map.
FILED	Thursday, October 23, 2014
APPL NO	14/521976
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4835 (20130101) G01R 33/5611 (20130101) Original (OR) Class G01R 33/5616 (20130101) G01R 33/5617 (20130101)
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09989611 — Systems and methods for image reconstruction using variable-density spiral trajectory

US 09989611	Zhao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Li Zhao (Charlottesville, Virginia); Craig H. Meyer (Charlottesville, Virginia)
ABSTRACT	In image reconstruction using a variable-density spiral trajectory, a method includes acquiring magnetic resonance (MR) data, which includes determining a multi-level undersampling pattern based on sampling distance and probability functions, and determining a desired variable-density spiral trajectory based on the undersampling pattern. Acquiring the MR data also includes generating spiral gradient waveforms based on the desired trajectory, and tracing a variable-density spiral trajectory using the spiral gradient waveforms. After tracing, the MR data can be sub-sampled based on the variable-density spiral trajectory. One or more images can be reconstructed based on the acquired MR data.
FILED	Thursday, April 02, 2015
APPL NO	14/677877
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4818 (20130101) G01R 33/4824 (20130101) G01R 33/5611 (20130101) Original (OR) Class
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09990856 — Systems and methods for providing vibration feedback in robotic systems

US 09990856	Kuchenbecker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Katherine J. Kuchenbecker (Philadelphia, Pennsylvania); Will McMahan (Philadelphia, Pennsylvania); Ernest D. Gomez (Philadelphia, Pennsylvania); Karlin Bark (Menlo Park, California)
ABSTRACT	Systems and methods for training an operator of a robotic surgery system are disclosed. One such method includes enabling the operator to perform a test procedure, recording vibrations of a surgical tool of the robotic surgery system during the test procedure, and generating a score for the operator based at least in part on the recorded vibrations of the surgical tool.
FILED	Friday, March 15, 2013
APPL NO	13/833122
ART UNIT	3715 — Amusement and Education Devices
CURRENT CPC	Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) Original (OR) Class G09B 23/285 (20130101)
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09991391 — Pristine and functionalized graphene materials

US 09991391	Dai et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Hongjie Dai (Cupertino, California); Xiaolin Li (Menlo Park, California); Xiaoming Sun (Beijing, China PRC)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Hongjie Dai (Cupertino, California); Xiaolin Li (Menlo Park, California); Xiaoming Sun (Beijing, China PRC)
ABSTRACT	Disclosed are dispersed graphene sheets, ribbons, graphene molecules and the like which are pristine in the plane, i.e., free of significant defects and chemical modifications such as oxidation. The materials could be functionalized at the edges. These materials are dispersed in solutions rather than in aggregated or insoluble forms as their parent starting materials. Also disclosed is a method comprising the steps of intercalating an insoluble graphitic material. The method may comprise exfoliating graphite and re-intercalating the resultant material with an acid composition, such as oleum, and a strong organic base such as tetrabutylammonium hydroxide in a solvent solution to form a homogenous suspension, which is then agitated to form dispersed graphene materials. The materials may be solubilized with a hydrophilic polymer and can be further manipulated by transfer into different solvents, formation of films, application to optical and electronic devices, and other applications. The materials are solubilized by functional groups mostly at the edges.
FILED	Friday, July 24, 2009
APPL NO	12/508754
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) C01B 32/22 (20170801) C01B 32/225 (20170801) C01B 2204/02 (20130101) C01B 2204/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/778 (20130101) H01L 29/1606 (20130101) H01L 29/78684 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115)
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Department of Defense (DOD)

09986720 — Mixed odor delivery device (MODD)

US 09986720	DeGreeff et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Lauryn E. DeGreeff (Washington, District of Columbia); Michael P. Malito (Washington, District of Columbia); Andrew Brandon (Williamsport, Pennsylvania); Christopher J. Katilie (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Lauryn E. DeGreeff (Washington, District of Columbia); Michael P. Malito (Washington, District of Columbia); Andrew Brandon (Williamsport, Pennsylvania); Christopher J. Katilie (Washington, District of Columbia)
ABSTRACT	An apparatus for training canines to detect complex hazardous substances from an odor mixture developed from at least two separated material components having at least two separated odors respectively. The training apparatus has a chamber base unit having at least two vial wells configured to hold separate containers of the material components and a chamber top unit having a first side facing the chamber base and a second side opposite the first side. The first side of the chamber top unit and the chamber base unit define a primary vapor mixing chamber in fluid communication with the vial wells. A mechanical seal between the chamber top and the chamber base seals the primary vapor mixing chamber. A passageway extends through the chamber top unit connecting the primary vapor mixing chamber to the second side of the chamber top unit.
FILED	Tuesday, December 22, 2015
APPL NO	14/978040
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 15/02 (20130101) Original (OR) Class
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09986915 — Systems and methods for a short wave infrared device

US 09986915	Carr et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Boston, Massachusetts)
INVENTOR(S)	Jessica Carr (Fairmont, West Virginia); Oliver Bruns (Boston, Massachusetts); Moungi Bawendi (Cambridge, Massachusetts); Tulio Valdez (Simsbury, Connecticut)
ABSTRACT	Systems and methods for a short wave infrared (SWIR) otoscope device are provided. The SWIR otoscope device can capture images of a patient's middle ear to aid in diagnosing one of a plurality of maladies. In one embodiment, the SWIR otoscope device can include a SWIR detector, a light source, and a plurality of optics that can enable the SWIR otoscope device to capture images of the middle ear of a patient.
FILED	Wednesday, July 27, 2016
APPL NO	15/221517
ART UNIT	3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 1/07 (20130101) A61B 1/00009 (20130101) A61B 1/32 (20130101) A61B 1/227 (20130101) A61B 1/0646 (20130101) A61B 1/0684 (20130101) A61B 5/12 (20130101) A61B 5/0086 (20130101) Original (OR) Class A61B 5/7282 (20130101)
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09986921 — Detection and monitoring of atrial fibrillation

US 09986921	Chon et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Worcester Polytechnic Institute (Worcester, Massachusetts)
ASSIGNEE(S)	WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts)
INVENTOR(S)	Ki H. Chon (Worcester, Massachusetts); Jowoon Chong (Worcester, Massachusetts)
ABSTRACT	A real-time arrhythmia discrimination method is used in smartphones, which can discriminate between NSR, AF, PACs and PVCs using pulsatile time series collected from a smartphone's camera. To increase the sensitivity of AF detection and add the new capabilities of PVC and PAC identification, the arrhythmia discrimination method of these teachings combines Root Mean Square of Successive RR Differences (RMSSD), Shannon Entropy (ShE) and turning point ratio (TPR), with the Poincare plot, and utilizes the features of pulse rise/fall time and amplitude for arrhythmia discrimination.
FILED	Friday, May 01, 2015
APPL NO	14/702601
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0464 (20130101) A61B 5/02405 (20130101) Original (OR) Class A61B 5/6898 (20130101) A61B 5/7282 (20130101)
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09986924 — Implantable biomedical devices on bioresorbable substrates

US 09986924	Rogers et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Energy (DOE)
APPLICANT(S)	THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois); Trustees of Tufts College (Medford, Massachusetts); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Urbana, Illinois); Fiorenzo Omenetto (Wakefield, Massachusetts); David L. Kaplan (Concord, Massachusetts); Brian Litt (Bala Cynwyd, Pennsylvania); Jonathan Viventi (Philadelphia, Pennsylvania); Yonggang Huang (Glencoe, Illinois); Jason Amsden (Eddington, Maine)
ABSTRACT	Provided herein are implantable biomedical devices and methods of administering implantable biomedical devices, making implantable biomedical devices, and using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment.
FILED	Tuesday, December 24, 2013
APPL NO	14/140299
ART UNIT	3739 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/04 (20130101) Original (OR) Class A61B 5/05 (20130101) A61B 5/6867 (20130101) A61B 2562/0285 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/047 (20130101) A61L 31/148 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/0551 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101)
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09987096 — System and method for MRI-guided breast interventions

US 09987096	Larson et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	MRI Robotics LLC (Saint Paul, Minnesota)
ASSIGNEE(S)	MRI Robotics LLC (Saint Paul, Minnesota)
INVENTOR(S)	Blake Timothy Larson (Saint Paul, Minnesota); Arthur Guy Erdman (New Brighton, Minnesota)
ABSTRACT	A method and apparatus for radially compressing bodily tissue and performing medical procedures from a selected one of a plurality of circumferential positions and angles, a selected one of a plurality of different elevations and elevational angles. Some embodiments include a tissue-compression fixture having members that are configured to be moved to radially compress bodily tissue such that each of a plurality of areas of biological tissue are exposed between the plurality of members, and wherein the fixture is compatible with use in an MRI machine in operation; an actuator having a receiver for a medical-procedure probe; and a computer system operatively coupled to the actuator to move the probe. The computer receives user commands, and based on the commands, moves the actuator to a selected one of a plurality of different positions around the tissue-compression fixture and then extends the probe into the patient.
FILED	Tuesday, January 31, 2017
APPL NO	15/421070
ART UNIT	3737 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0555 (20130101) A61B 5/708 (20130101) A61B 10/0041 (20130101) A61B 10/0266 (20130101) A61B 90/11 (20160201) A61B 90/17 (20160201) Original (OR) Class A61B 2010/045 (20130101) A61B 2090/374 (20160201) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/30 (20130101) G01R 33/286 (20130101) G01R 33/5608 (20130101)
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09987241 — Enzyme conjugate and prodrug cancer therapy

US 09987241	Harrison, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S)	Roger G. Harrison, Jr. (Norman, Oklahoma); John J. Krais (Abington, Pennsylvania)
ABSTRACT	A method and composition for treating a cancerous tumor in a subject by targeting the tumor's vasculature using an enzyme conjugate comprising a ligand which binds to endothelial cells in the tumor vasculature and converts a prodrug administered to the subject into an anticancer drug in the tumor vasculature.
FILED	Friday, September 25, 2015
APPL NO	14/865650
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/664 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 38/51 (20130101) A61K 45/06 (20130101) A61K 47/67 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Enzymes C12Y 404/01001 (20130101)
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09987749 — Control interface for robotic humanoid avatar system and related methods

US 09987749	Nagendran et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S)	University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S)	Arjun Nagendran (Oakland, California); Brian Kelly (Winter Garden, Florida)
ABSTRACT	A system and method for controlling a humanoid robot from a remote location are provided. One or more sensing devices are used to sense positions and movements of a user at an inhabiter station. A computing device generates a virtual character based upon the sensed positions and movements of the user and provides a plurality of outputs for controlling the humanoid robot based upon motion of the virtual character. The computing device includes a master controller to generate the virtual character and its behaviors and to transmit instructions to control motion of the humanoid robot to a slave controller located at the humanoid robot, providing smooth and natural motion of the humanoid robot. The method permits switching between multiple virtual characters in a single scene to control and alter the behavior of one or more humanoid robots located in several geographic locations.
FILED	Monday, August 17, 2015
APPL NO	14/827701
ART UNIT	3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Manipulators; Chambers Provided With Manipulation Devices B25J 9/0081 (20130101) B25J 9/1605 (20130101) B25J 9/1615 (20130101) B25J 9/1689 (20130101) Original (OR) Class Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/36436 (20130101) G05B 2219/36442 (20130101) G05B 2219/40116 (20130101) G05B 2219/40264 (20130101)
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09987996 — Vehicle with at least one multipurpose equipment item mounted on a winch and associated methods of use

US 09987996	Brown
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Surface Warfare Center (NSWC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Christopher A. Brown (Bloomington, Indiana)
ABSTRACT	A vehicle recovery or anchoring system is provided including a winch coupled to a vehicle, a cable retractably disposed in the winch, a selectively removable dual use vehicle component and anchoring structure (DUVCAC), e.g., a spare tire, and a retaining structure that is configured to retract and hold the DUVCAC or extend the same based on operation of the winch. The cable is adapted to selectively couple and decouple with the retaining structure, wherein the cable is passed through a section of the DUVCAC and be drawn against the vehicle and/or winch. Different types of retaining structures are provided including retaining structures that are formed with additional anchoring elements, e.g., folding spades, as well as different structures, e.g., cable sections or loops, to couple with the DUVCAC. Different cable configurations as well as coupling arrangements are also provided. Various methods are also provided.
FILED	Thursday, September 03, 2015
APPL NO	14/845210
ART UNIT	3638 — Static Structures, Supports and Furniture
CURRENT CPC	Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 9/06 (20130101) Original (OR) Class Motor Vehicles; Trailers B62D 43/02 (20130101)
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09988316 — Protective internal coatings for porous substrates

US 09988316	Sambasivan et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Warfare Center (NAWC)
APPLICANT(S)	Applied Thin Films Inc. (Skokie, Illinois)
ASSIGNEE(S)	Applied Thin Films, Inc. (Skokie, Illinois)
INVENTOR(S)	Sankar Sambasivan (Chicago, Illinois); Vikram Sharad Kaul (Atlanta, Georgia); Francis Richard Chapman (Mount Prospect, Illinois)
ABSTRACT	A material contains open pores in which the channels and pores that are internally coated with at least one layer of phosphorus-containing alumina. Such material is formed by infiltrating a porous material one or more times with a non-colloidal, low-viscosity liquid coating precursor, drying, and curing the coating precursor to form a phosphorus-containing alumina layer within pores of the material.
FILED	Tuesday, February 03, 2015
APPL NO	14/612482
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 35/83 (20130101) C04B 35/195 (20130101) C04B 35/522 (20130101) C04B 35/522 (20130101) C04B 35/565 (20130101) C04B 35/565 (20130101) C04B 35/584 (20130101) C04B 35/584 (20130101) C04B 35/584 (20130101) C04B 35/806 (20130101) C04B 35/806 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/0054 (20130101) C04B 38/0096 (20130101) Original (OR) Class C04B 38/0096 (20130101) C04B 38/0096 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/85 (20130101) C04B 41/4515 (20130101) C04B 41/5092 (20130101) C04B 41/5092 (20130101) C04B 2235/3206 (20130101) C04B 2235/3208 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/125 (20130101) C23C 18/1216 (20130101) C23C 18/1229 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/514 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/268 (20150115) Y10T 428/24997 (20150401) Y10T 428/249921 (20150401) Y10T 428/249967 (20150401) Y10T 428/249969 (20150401) Y10T 428/249978 (20150401)
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09988424 — Immunogens comprising human immunodeficiency virus V1/V2 polypeptides

US 09988424	Haynes et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center (VRC)
APPLICANT(S)	DUKE UNIVERSITY (Durham, North Carolina); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia); NEW YORK UNIVERSITY (New York, New York)
ASSIGNEE(S)	DUKE UNIVERSITY (Durham, North Carolina); U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (Fort Detrick, Maryland); NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S)	Barton F. Haynes (Durham, North Carolina); Huaxin Liao (Durham, North Carolina); Jerome Kim (Fort Detrick, Maryland); Nelson Michael (Fort Detrick, Maryland); Susan B. Zolla-Pazner (New York, New York)
ABSTRACT	The invention is generally directed to V1V2 immunogens.
FILED	Wednesday, December 05, 2012
APPL NO	14/363131
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/162 (20130101) C07K 16/1063 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24043 (20130101) C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101)
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09988426 — Broad spectrum conjugate vaccine to prevent Klebsiella pneumoniae and Pseudomonas aeruginosa infections

US 09988426	Simon et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Raphael Simon (Baltimore, Maryland); Alan Cross (Chevy Chase, Maryland); Sharon Tennant (Baltimore, Maryland)
ASSIGNEE(S)	UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S)	Raphael Simon (Baltimore, Maryland); Alan Cross (Chevy Chase, Maryland); Sharon Tennant (Baltimore, Maryland)
ABSTRACT	The present invention is drawn to conjugates and vaccine compositions comprising a Pseudomonas flagellin or an antigenic fragment or derivative thereof linked to one or more Klebsiella surface polysaccharide antigens, such as Klebsiella pneumoniae O polysaccharide from serovars O1, O2a, O2a,c, O3, O4, O5, O7, O8 and 012. The present invention also provides serovar reagent strains to produce the conjugates and vaccine compositions and methods of inducing an immune response with the conjugates and vaccine compositions.
FILED	Friday, September 18, 2015
APPL NO	15/509041
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/104 (20130101) A61K 39/0266 (20130101) A61K 47/4833 (20130101) A61K 2039/70 (20130101) Peptides C07K 14/21 (20130101) C07K 14/26 (20130101) Original (OR) Class
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09988612 — T7 RNA polymerase variants with expanded substrate range and enhanced transcriptional yield

US 09988612	Ellington et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Andrew D. Ellington (Austin, Texas); Adam J. Meyer (Austin, Texas)
ABSTRACT	Disclosed are T7 RNA polymerase variants with enhanced transcriptional activity. T7 RNA polymerase variants are known which have the ability to incorporate modified ribonucleotides into growing RNA molecules. However, these variants have relatively low levels of transcriptional activity. Presented herein are mutations that increase the transcriptional activity of the variants with broad substrate range.
FILED	Friday, March 20, 2015
APPL NO	15/127617
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1247 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2320/51 (20130101) C12N 2330/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 207/07006 (20130101)
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09988617 — Engineered heme-binding compositions and uses thereof

US 09988617	Super et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Michael Super (Lexington, Massachusetts); Alexander L. Watters (Melrose, Massachusetts); Philip T. Snell (Lexington, Massachusetts); Donald E. Ingber (Boston, Massachusetts)
ABSTRACT	Described herein are heme-binding compositions and methods relating to their use, e.g. methods of treatment of, for example, sepsis and rhabdomyolysis.
FILED	Wednesday, May 21, 2014
APPL NO	14/892252
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/805 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 9/2474 (20130101) Original (OR) Class Enzymes C12Y 302/01035 (20130101)
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09988623 — Methods of X-aptamer generation and compositions thereof

US 09988623	Gorenstein et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Child Health and Human Development (NICHD) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Board of Regents of the University of Texas System (Austin, Texas); AM Biotechnologies, LLC (Houston, Texas)
ASSIGNEE(S)	AM Biotechnologies, LLC (Houston, Texas); Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	David G Gorenstein (Houston, Texas); Weiguo He (Pearland, Texas); David E Volk (Dickinson, Texas); Miguel-Angel Elizondo-Riojas (Houston, Texas); Ross Durland (The Woodlands, Texas); Johnnie Engelhardt (West Columbia, Texas)
ABSTRACT	Provided herein are methods for a novel bead-based next-generation “X-aptamer” selection scheme that extends aptamer technology to include X-modified bases, thus resulting in X-aptamers, at any position along the sequence because the aptamers are chemically synthesized via a split-pool scheme on individual beads. Also provides are application to a wide range of commonly used DNA modifications, including, but not limited to, monothioate and dithioate backbone substitutions. This new class of aptamer allows chemical modifications introduced to any of the bases in the aptamer sequence as well as the phosphate backbones and can be extended to other carbohydrate-based systems.
FILED	Thursday, October 10, 2013
APPL NO	14/051363
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1048 (20130101) C12N 15/1058 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/315 (20130101) C12N 2310/351 (20130101) C12N 2320/11 (20130101) C12N 2330/31 (20130101)
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09988631 — Pharmaceutical composition comprising Nanog shRNA, and method of using Nanog shRNA to treat cancer

US 09988631	Jessup et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	John Milburn Jessup (Potomac, Maryland); Nikolay Korokhov (Germantown, Maryland)
ABSTRACT	The present description relates to an inhibitory RNA molecule, comprising an oligonucleotide that selectively knocks down expression a Nanog pseudogene expressed in many human cancers, a replicating viral vector capable of encoding such inhibitory RNA molecule, pharmaceutical compositions comprising said vector, and methods of treating cancer by administration of said pharmaceutical composition.
FILED	Wednesday, October 26, 2016
APPL NO	15/334666
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/32 (20130101) C12N 2710/10032 (20130101) C12N 2710/10043 (20130101) C12N 2710/10045 (20130101) C12N 2799/022 (20130101) C12N 2799/028 (20130101) C12N 2820/007 (20130101) C12N 2830/008 (20130101)
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09988659 — In vivo conversion of nucleosides in plasmid DNA

US 09988659	Benner et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Steven A Benner (Gainesville, Florida); Ryan Shaw (Gainesville, Florida)
ASSIGNEE(S)
INVENTOR(S)	Steven A Benner (Gainesville, Florida); Ryan Shaw (Gainesville, Florida)
ABSTRACT	The instant invention provides for the assembly of large DNA oligonucleotide constructs by the self-assembly of multiple oligonucleotide fragments, wherein the assembly is guided by the hybridization between non-standard nucleotides that form non-standard nucleobase pairs orthogonal to the standard T:A and C:G nucleobase pairs. Adding nucleobase pairs increases the information density of the fragments, minimizing off-target hybridization. The invention further provides rules and methods for converting non-standard pairs into standard pairs using polymerase copying with conversion.
FILED	Tuesday, March 18, 2014
APPL NO	14/218405
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class
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09988687 — Companion diagnostics for cancer and screening methods to identify companion diagnostics for cancer based on splicing variants

US 09988687	Lee et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Norman Lee (Dayton, Maryland); Bi-Dar Wang (Potomac, Maryland)
ASSIGNEE(S)	THE GEORGE WASHINGTON UNIVERISTY (, District of Columbia)
INVENTOR(S)	Norman Lee (Dayton, Maryland); Bi-Dar Wang (Potomac, Maryland)
ABSTRACT	A method of classifying a patient for eligibility for cancer therapy based on the presence or absence of splicing variants in a sample of the patient's cancer tissue. Also, a method of screening cancer therapies for efficacy against splicing variants. More specifically, the methods relate to novel splicing variants of genes associated with cancer risk and survival, particularly splicing variants of PIK3CD, FGFR3, TSC2, RASGRP2, ITGA4, MET, NF1 and BAK1. Also more specifically, the methods relate to classifying a patient for eligibility for cancer therapy involving the use of GS-1101.
FILED	Thursday, March 05, 2015
APPL NO	14/639219
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101)
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09988746 — Partially degradable fibers and microvascular materials formed from the fibers

US 09988746	Dong et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Hefei Dong (Urbana, Illinois); Stephen J. Pety (Urbana, Illinois); Nancy R. Sottos (Champaign, Illinois); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois)
ABSTRACT	A partially degradable polymeric fiber includes a thermally degradable polymeric core and a coating surrounding at least a portion of the core. The thermally degradable polymeric core includes a polymeric matrix including a poly(hydroxyalkanoate), and a metal selected from the group consisting of an alkali earth metal and a transition metal, in the core polymeric matrix. The concentration of the metal in the polymeric matrix is at least 0.1 wt %. The partially degradable polymeric fiber may be used to form a microvascular system containing one or more microfluidic channels.
FILED	Friday, September 27, 2013
APPL NO	14/040287
ART UNIT	1789 — Miscellaneous Articles, Stock Material
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 15/00 (20130101) D03D 25/005 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2509/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/145 (20130101) H01M 2/162 (20130101) H01M 2/1653 (20130101) H01M 10/052 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/294 (20150115) Y10T 428/2933 (20150115) Y10T 442/30 (20150401)
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09988912 — Thermal regulation channels for turbomachine components

US 09988912	Waite et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Ryan A. Waite (South Windsor, Connecticut); Benjamin F. Hagan (Manchester, Connecticut)
ABSTRACT	A turbomachine component (e.g., a blade, vane, or any other suitable component) is defined at least partially in a radial direction and an axial direction orthogonal to the radial direction and includes a body defining an outer surface configured to be in thermal communication with a gas path flow in the axial direction. The component includes a thermal regulation channel system defined within the body which includes at least one radial channel configured to allow thermal regulation flow in the radial direction, and at least one axial channel configured to allow thermal regulation flow in the axial direction.
FILED	Friday, May 08, 2015
APPL NO	14/707988
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class F01D 25/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/50 (20130101) F05D 2240/12 (20130101) F05D 2260/202 (20130101) F05D 2260/232 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) Y02T 50/676 (20130101)
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09988932 — Bi-cast turbine nozzles and methods for cooling slip joints therein

US 09988932	Riahi et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	HONEYWELL INTERNATIONAL INC. (Morristown, New Jersey)
ASSIGNEE(S)	HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
INVENTOR(S)	Ardeshir Riahi (Scottsdale, Arizona); Lorenzo Crosatti (Phoenix, Arizona)
ABSTRACT	Bi-cast turbine nozzles and methods for cooling the same are provided. The bi-cast turbine nozzle comprises an endwall. A vane is coupled to the endwall. The vane comprises an end portion and a leading edge and a trailing edge interconnected by a pressure sidewall and a suction sidewall. A slip joint is provided between the end portion and the endwall. A plurality of cooling holes is defined through the endwall. The plurality of cooling holes is disposed adjacent the periphery of the slip joint along the pressure sidewall of the vane and in proximity to the leading edge of the vane.
FILED	Friday, December 06, 2013
APPL NO	14/099289
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) F01D 5/18 (20130101) F01D 5/22 (20130101) F01D 5/145 (20130101) F01D 5/186 (20130101) F01D 9/00 (20130101) F01D 9/041 (20130101) F01D 9/042 (20130101) F01D 25/12 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101) Y02T 50/676 (20130101)
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09988934 — Gas turbine engines including channel-cooled hooks for retaining a part relative to an engine casing structure

US 09988934	Spangler
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S)	Brandon W. Spangler (Vernon, Connecticut)
ABSTRACT	A gas turbine engine is provided. The gas turbine engine includes an engine casing structure and a part retained relative to the engine casing structure by a channel-cooled hook. The channel-cooled hook includes at least a portion of a hook cooling channel. A vane assembly for the gas turbine engine is also provided.
FILED	Thursday, July 23, 2015
APPL NO	14/807703
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/042 (20130101) F01D 25/12 (20130101) Original (OR) Class F01D 25/14 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/22141 (20130101)
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09989043 — System and method for processor-based security

US 09989043	Lee et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Teleputers, LLC (Princeton, New Jersey)
ASSIGNEE(S)	Teleputers, LLC (Princeton, New Jersey)
INVENTOR(S)	Ruby B. Lee (Princeton, New Jersey); David Champagne (London, United Kingdom)
ABSTRACT	A system and method for processor-based security is provided, for on-chip security and trusted computing services for software applications. A processor is provided having a processor core, a cache memory, a plurality of registers for storing at least one hash value and at least one encryption key, a memory interface, and at least one on-chip instruction for creating a secure memory area in a memory external to the processor, and a hypervisor program executed by the processor. The hypervisor program instructs the processor to execute the at least one on-chip instruction to create a secure memory area for a software area for a software module, and the processor encrypts data written to, and decrypts data read from, the external memory using the at least one encryption key and the verifying data read from the external memory using the at least one hash value.
FILED	Tuesday, October 10, 2017
APPL NO	15/729401
ART UNIT	2497 — Cryptography and Security
CURRENT CPC	Positive-displacement Machines for Liquids; Pumps F04B 33/00 (20130101) Original (OR) Class Electric Digital Data Processing G06F 21/57 (20130101) G06F 21/72 (20130101) G06F 21/575 (20130101)
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09989078 — Swirling jet actuator for control of separated and mixing flows

US 09989078	Taira et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S)	The Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S)	Kunihiko Taira (Tallahassee, Florida); Farrukh Alvi (Tallahassee, Florida); Phillip Munday (Niceville, Florida)
ABSTRACT	The present invention includes a method of controlling a fluid flow using momentum and/or vorticity injections. Actively controlling an actuator allows for direct, precise, and independent control of the momentum and swirl entering into the fluid system. The perturbations are added to the flow field in a systematic mater providing tunable control input, thereby modifying behavior thereof in a predictable manner to improve the flow characteristics.
FILED	Monday, August 29, 2016
APPL NO	15/250330
ART UNIT	3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeroplanes; Helicopters B64C 21/08 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/007 (20130101) F15D 1/009 (20130101) Original (OR) Class F15D 1/12 (20130101)
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09989355 — Method and apparatus for conducting real-time process control of particle and fiber generation

US 09989355	Skinner et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Jack L. Skinner (Butte, Montana); Joshua D. Beisel (Butte, Montana); Marvin J. Franson (Butte, Montana); Bryce Hill (Butte, Montana)
ASSIGNEE(S)
INVENTOR(S)	Jack L. Skinner (Butte, Montana); Joshua D. Beisel (Butte, Montana); Marvin J. Franson (Butte, Montana); Bryce Hill (Butte, Montana)
ABSTRACT	A linear stage moves a laser along the collection plate of an electrospinning device. The stage supports the laser that is moved through the electrospinning/electrospraying deposition field by a continuous rotation servo motor. Stage movement is controlled by a control unit. Signal voltages collected are sectioned into concentric layers so that the extinction coefficient for each layer can be calculated without including the extinction coefficient from the previous layer. The extinction coefficients were used in the Beer-Lambert law to determine the diameter of fibers being deposited on the collection plate as well as the concentration of fibers deposited indicating deposition speed.
FILED	Friday, July 15, 2016
APPL NO	15/212144
ART UNIT	2877 — Optics
CURRENT CPC	Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0061 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/08 (20130101) Original (OR) Class
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09989359 — Nondestructive, absolute determination of thickness of or depth in dielectric materials

US 09989359	Little, Jr.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Evisive, Inc. (Baton Rouge, Louisiana)
ASSIGNEE(S)	Evisive, Inc. (Baton Rouge, Louisiana)
INVENTOR(S)	Jack R. Little, Jr. (Baton Rouge, Louisiana)
ABSTRACT	Enhanced measurement of thickness in bulk dielectric materials is disclosed. Microwave radiation is partially reflected at interfaces where the dielectric constant changes (e.g., the back wall of a part). The reflected microwaves are combined with a portion of the outgoing beam at each of at least two separate detectors. A pair of sinusoidal or quasi-sinusoidal waves results. Thickness or depth measurement is enhanced by exploiting the phase and amplitude relationships between multiple sinusoidal or quasi-sinusoidal standing waves at detectors sharing a common microwave source. These relationships are used to determine an unambiguous relationship between the signal and the thickness or depth.
FILED	Monday, September 22, 2014
APPL NO	15/023297
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 15/02 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) G01N 22/02 (20130101)
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09989625 — Sky polarization and sun sensor system and method

US 09989625	Aycock et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Polaris Sensor Technologies, Inc. (Huntsville, Alabama)
ASSIGNEE(S)	Polaris Sensor Technologies, Inc. (Huntsville, Alabama)
INVENTOR(S)	Todd Michael Aycock (Huntsville, Alabama); David B. Chenault (Huntsville, Alabama); Arthur Lompado (Huntsville, Alabama); J. Larry Pezzaniti (Huntsville, Alabama)
ABSTRACT	A system for determining a new orientation and/or position of an object comprises a sky polarimeter configured to record image data of the sky, a signal processing unit, and logic configured to receive and store in memory the image data received from the sky polarimeter. The logic calculates the Stokes parameters (S₀, S₁, S₂,), DoLP, and AoP from the image data, detects obscurants and filters the obscurants (such as clouds and trees) from the image data to produce a filtered image. The logic is further configured to find the Sun and zenith in the filtered image, and to determine the roll, pitch, yaw, latitude and longitude of the object using the filtered image. A method for determining a new position/orientation of an object comprises recording raw image data using a sky polarimeter, calculating S₀, S₁, S₂, DoLP, and AoP from the image data, detecting obscurants and filtering the obscurants from the image data to produce a filtered image, obtaining last known position/orientation data of the object, finding the Sun and zenith in the filtered image, and determining the roll, pitch, yaw, latitude and longitude of the object using the filtered image.
FILED	Thursday, August 18, 2016
APPL NO	15/240663
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/7862 (20130101) G01S 5/163 (20130101) Original (OR) Class G01S 5/0263 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00671 (20130101) G06K 9/4604 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 2207/20061 (20130101) G06T 2207/30181 (20130101) Pictorial Communication, e.g Television H04N 7/183 (20130101)
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09989677 — Ultra-thin, planar, plasmonic metadevices

US 09989677	Shalaev et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Air Force Research Laboratory (AFRL) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S)	Vladimir Shalaev (West Lafayette, Indiana); Alexander Kildishev (West Lafayette, Indiana); Xingjie Ni (West Lafayette, Indiana); Satoshi Ishii (Hyogo, Japan)
ABSTRACT	An ultra-thin planar device is used for arbitrary waveform formation on a micrometer scale, regardless of the incident light's polarization. Patterned perforations are made in a 30 nm-thick metal film, creating discrete phase shifts and forming a desired wavefront of cross-polarized, scattered light. The signal-to-noise ratio of these devices is at least one order of magnitude higher than current metallic nano-antenna designs. The focal length of a lens built on such principle can also be adjusted by changing the wavelength of the incident light. All proposed embodiments can be embedded, for example, on a chip or at the end of an optical fiber.
FILED	Wednesday, September 04, 2013
APPL NO	14/427052
ART UNIT	2872 — Optics
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/834 (20130101)
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09989702 — Polarization rotator for silicon photonics

US 09989702	Doany et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Fuad E. Doany (Katonah, New York); Nicolas Dupuis (New York, New York); Benjamin G. Lee (New York, New York); Frank R. Libsch (White Plains, New York); Jeonghwan Song (Heverlee, Belgium)
ABSTRACT	A photonic waveguide structure for performing polarization rotation includes a first waveguide layer including input and output waveguides. The input and output waveguides are separate and discontinuous structures. The input and output waveguides are configured in the first waveguide layer to have a lateral offset therebetween. The photonic waveguide structure further includes a second waveguide layer including a waveguide structure disposed under or over the first waveguide layer. The waveguide structure includes a polarization conversion region configured within the second waveguide layer to overlap the input or output waveguides in the first waveguide layer.
FILED	Tuesday, November 24, 2015
APPL NO	14/950359
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/126 (20130101) Original (OR) Class G02B 6/1221 (20130101) G02B 6/1228 (20130101) G02B 6/2726 (20130101) G02B 6/2766 (20130101) G02B 27/0012 (20130101)
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09989730 — Alignment of an optical component

US 09989730	Ohnstein et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Honeywell International Inc. (Morristown, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Thomas Ohnstein (Roseville, Minnesota); Bernard S. Fritz (Eagan, Minnesota); Daniel Youngner (Maple Grove, Minnesota)
ABSTRACT	Methods, apparatuses, and systems for alignment of an optical component are described herein. One method includes forming a pit in a substrate, placing an optical component in the pit, and aligning the optical component such that an edge of the optical component is in physical contact with an alignment edge of the pit.
FILED	Tuesday, July 14, 2015
APPL NO	14/798941
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 7/1822 (20130101) Original (OR) Class
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09989785 — In-situ ring-resonator-modulator calibration

US 09989785	Amberg et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Oracle International Corporation (Redwood City, California)
ASSIGNEE(S)	Oracle International Corporation (Redwood Shores, California)
INVENTOR(S)	Philip Amberg (El Cajon, California); Eric Y. Chang (San Mateo, California); Frankie Y. Liu (Palo Alto, California)
ABSTRACT	In an optical device, a ring-resonator modulator, having an adjustable resonance (center) wavelength, receives an optical signal that includes a carrier wavelength from an input-output optical waveguide. Then, a monitoring mechanism monitors a performance metric (such as an average power or a signal swing) of a monitor optical signal from the ring-resonator modulator. Moreover, control logic in the optical device adjusts the resonance wavelength based on the monitored performance metric so that the resonance wavelength is locked to the carrier wavelength. In particular, the control logic may apply a change to an adjustment signal that is provided to the ring-resonator modulator. If the change increases the performance metric, the control logic may continue to modify the resonance wavelength. Otherwise, the control logic may modify the resonance wavelength by applying one or more changes, having an opposite sign to the change, to the adjustment signal.
FILED	Tuesday, August 19, 2014
APPL NO	14/463654
ART UNIT	2874 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0121 (20130101) Original (OR) Class G02F 1/3132 (20130101) G02F 2201/58 (20130101) G02F 2203/15 (20130101)
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09989831 — Chip-scale two-dimensional optical phased array with simplified controls

US 09989831	Pruessner et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Marcel W. Pruessner (Chevy Chase, Maryland); William S. Rabinovich (Silver Spring, Maryland); Rita Mahon (Silver Spring, Maryland); Peter G. Goetz (Springfield, Virginia)
ABSTRACT	A device includes an optical splitter comprising a plurality of splitter outputs. The splitter outputs are out of phase and include a non-uniform phase front. The device includes a one-dimensional phase compensation array communicating with the optical splitter. The phase compensation array receives the non-uniform phase front and outputs a uniform phase front. The phase compensation array includes a plurality of array outputs. The device includes a tunable linear gradient phase shifter communicating with said phase compensation array to impart a linearly-varying phase shift across said plurality of array outputs, thereby steering a beam along a first angle in a first plane. The device includes a waveguide grating out-coupler communicating with said linear gradient phase shifter, and a uniform phase shifter communicating with the waveguide grating out-coupler. The uniform phase shifter steers the flat phase front along a second angle in a second plane perpendicular to said first plane.
FILED	Thursday, March 02, 2017
APPL NO	15/447297
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/124 (20130101) G02B 6/2813 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) Original (OR) Class G02F 2201/06 (20130101)
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09990266 — Data recorder for full event capture

US 09990266	Moffatt
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Sikorsky Aircraft Corporation (Stratford, Connecticut)
ASSIGNEE(S)	SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut)
INVENTOR(S)	Ronald Moffatt (Rochester, New York)
ABSTRACT	Embodiments are directed to capturing data associated with an occurrence of an event via a battery-powered recorder, comprising: storing analog data in a delay circuit while a recording circuit is powered off, detecting, by a trigger circuit, the occurrence of the event while the recording circuit is powered off, powering-on the recording circuit based on the detection of the event, converting samples of analog data associated with the event provided by the delay circuit to a digital format while the recording circuit powers on, and storing the converted digital samples after the recording circuit has powered on, wherein a time delay associated with the delay circuit is greater than a time it takes for the recording circuit to power-on.
FILED	Thursday, December 26, 2013
APPL NO	14/140713
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 2560/0242 (20130101) A61B 2562/0247 (20130101) Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 19/01 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/14 (20130101) G01L 5/0052 (20130101) G01L 9/008 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 1/127 (20130101) Electric Digital Data Processing G06F 11/3476 (20130101) Original (OR) Class Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 20/10527 (20130101)
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09990687 — Systems and methods for fast and repeatable embedding of high-dimensional data objects using deep learning with power efficient GPU and FPGA-based processing platforms

US 09990687	Kaufhold et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Deep Learning Analytics, LLC (Arlington, Virginia)
ASSIGNEE(S)	Deep Learning Analytics, LLC (Arlington, Virginia)
INVENTOR(S)	John Patrick Kaufhold (Arlington, Virginia); Michael Jeremy Trammell (Portland, Oregon)
ABSTRACT	Embodiments of the present invention are directed to providing new systems and methods for using deep learning techniques to generate embeddings for high dimensional data objects that can both simulate prior art embedding algorithms and also provide superior performance compared to the prior art methods. Deep learning techniques used by embodiments of the present invention to embed high dimensional data objects may comprise the following steps: (1) generating an initial formal embedding of selected high-dimensional data objects using any of the traditional formal embedding techniques; (2a) designing a deep embedding architecture, which includes choosing the types and numbers of inputs and outputs, types and number of layers, types of units/nonlinearities, and types of pooling, for example, among other design choices, typically in a convolutional neural network; (2b) designing a training strategy; (2c) tuning the parameters of a deep embedding architecture to reproduce, as reliably as possible, the generated embedding for each training sample; (3) optionally deploying the trained deep embedding architecture to convert new high dimensional data objects into approximately the same embedded space as found in step (1); and optionally (4) feeding the computed embeddings of high dimensional objects to an application in a deployed embodiment.
FILED	Thursday, March 09, 2017
APPL NO	15/454845
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) Image Data Processing or Generation, in General G06T 1/005 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 1/32154 (20130101) H04N 1/32267 (20130101)
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09990736 — Robust anytime tracking combining 3D shape, color, and motion with annealed dynamic histograms

US 09990736	Held et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	David Held (Stanford, California); Jesse Levinson (Stanford, California); Sebastian Thrun (Stanford, California); Silvio Savarese (Stanford, California)
ABSTRACT	Velocity controllers in accordance with embodiments of the invention enable velocity estimation for tracked objects. One embodiment includes a tracker controller, including: a processor; and a memory containing: a velocity tracker application; a state space describing relationships between measured locations, calculated locations, and changes in locations, where the calculated locations in the state space correspond to unoccluded points on the surface of the tracked object; wherein the processor is configured by the velocity tracker application to: pre-process the state space to identify a tracked object; estimate a velocity of the tracked object using a location history calculated from the measured locations of the tracked object within the state space and a motion model calculated from the state space; and return the velocity of the tracked object.
FILED	Monday, July 17, 2017
APPL NO	15/652013
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/207 (20170101) G06T 7/277 (20170101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/20016 (20130101) G06T 2207/20076 (20130101)
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09990766 — Method and system for predicting collision probability of space objects via graphics processing unit

US 09990766	Jia et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Intelligent Fusion Technology, Inc (Germantown, Maryland)
ASSIGNEE(S)	INTELLIGENT FUSION TECHNOLOGY, INC (Germantown, Maryland)
INVENTOR(S)	Bin Jia (Germantown, Maryland); Kui Liu (Germantown, Maryland); Genshe Chen (Germantown, Maryland); Khanh D. Pham (Kirtland AFB, New Mexico); Erik Blasch (Rome, New York)
ABSTRACT	Method and system for predicting collision probability of space objects are provided. Space objects are allocated according to a total number thereof for parallel computation in a GPU device. Initial orbit states of the space objects are generated by an initial-orbit-state generation kernel of the GPU device. Orbit propagation for each space object is performed based on the initial orbit state to predict a state of each space object by an orbit propagation kernel of the GPU device. The predicted states of the space objects are collected by a predicted-orbit-state collection kernel of the GPU device. A real-time visualization and rendering of the predicted space objects are performed in a form of point cloud during interactions between CPU threads and GPU kernels. A CPU host predicts a collision probability of any two space objects among the multitude of space objects, according to the interactions between the CPU threads and the GPU kernels.
FILED	Thursday, October 29, 2015
APPL NO	14/927428
ART UNIT	2617 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 17/00 (20130101) Original (OR) Class G06T 19/006 (20130101) G06T 2210/21 (20130101)
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09991113 — Systems and methods for fabricating single-crystalline diamond membranes

US 09991113	Kim et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Jeehwan Kim (Cambridge, Massachusetts); Dirk Robert Englund (Cambridge, Massachusetts); Mark A. Hollis (Concord, Massachusetts); Travis Wade (Harvard, Massachusetts); Michael Geis (Acton, Massachusetts); Richard Molnar (Harvard, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Jeehwan Kim (Cambridge, Massachusetts); Dirk Robert Englund (Cambridge, Massachusetts); Mark A. Hollis (Concord, Massachusetts); Travis Wade (Harvard, Massachusetts); Michael Geis (Acton, Massachusetts); Richard Molnar (Harvard, Massachusetts)
ABSTRACT	A buffer layer is employed to fabricate diamond membranes and allow reuse of diamond substrates. In this approach, diamond membranes are fabricated on the buffer layer, which in turn is disposed on a diamond substrate that is lattice-matched to the diamond membrane. The weak bonding between the buffer layer and the diamond substrate allows ready release of the fabricated diamond membrane. The released diamond membrane is transferred to another substrate to fabricate diamond devices, while the diamond substrate is reused for another fabrication.
FILED	Monday, June 05, 2017
APPL NO	15/613396
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0245 (20130101) H01L 21/0262 (20130101) H01L 21/02376 (20130101) H01L 21/02444 (20130101) H01L 21/02527 (20130101) Original (OR) Class H01L 21/02598 (20130101) H01L 21/02645 (20130101) H01L 21/6835 (20130101) H01L 21/30604 (20130101) H01L 21/32133 (20130101) H01L 29/04 (20130101) H01L 29/1602 (20130101) H01L 2221/68363 (20130101) H01L 2221/68381 (20130101) H01L 2221/68386 (20130101)
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09991311 — Dual active layer semiconductor device and method of manufacturing the same

US 09991311	Smith et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Joseph T. Smith (Tempe, Arizona); Michael Marrs (Phoenix, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Joseph T. Smith (Tempe, Arizona); Michael Marrs (Phoenix, Arizona)
ABSTRACT	Some embodiments include an imaging system. The imaging system includes an active matrix pixel array having a flexible substrate and a pixel. The pixel includes a transistor over the flexible substrate, and the transistor includes multiple active layers having a first active layer and a second active layer over the first active layer. Further, the active matrix pixel array also includes a photodiode over the transistor, and the photodiode includes an N-type layer over the transistor, an I layer over the N-type layer, and a P-type layer over the I layer. Meanwhile, the imaging system also includes a flexible scintillator layer over the active matrix pixel array. Other embodiments of related systems and methods are also disclosed.
FILED	Monday, March 09, 2015
APPL NO	14/642563
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/6835 (20130101) H01L 27/14636 (20130101) H01L 27/14663 (20130101) Original (OR) Class H01L 29/66765 (20130101) H01L 29/78603 (20130101) H01L 31/105 (20130101) H01L 31/03926 (20130101) H01L 2221/6835 (20130101) H01L 2924/3025 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0393 (20130101) H05K 2201/068 (20130101) H05K 2201/0145 (20130101) H05K 2201/0154 (20130101) H05K 2201/10128 (20130101)
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09991354 — Metal nitride alloy contact for semiconductor

US 09991354	Anderson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Travis J. Anderson (Alexandria, Virginia); Virginia D. Wheeler (Alexandria, Virginia); David Shahin (Springfield, Virginia); Andrew D. Koehler (Alexandria, Virginia); Karl D. Hobart (Alexandria, Virginia); Francis J. Kub (Arnold, Maryland); Marko J. Tadjer (Springfield, Virginia)
ABSTRACT	Systems and methods are provided that enable the production of semiconductor devices having a metal nitride layer in direct contact with a semiconductor layer to form a Schottky diode, such as a TiN gate on an AlGaN/GaN high electron mobility transistor (HEMT). Metal nitrides offer exceptional thermal stability and a lower diffusion coefficient. Technology enabled by embodiments of the present disclosure improves the reliability of GaN-based microwave power transistors.
FILED	Tuesday, May 16, 2017
APPL NO	15/596933
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) H01L 29/401 (20130101) H01L 29/475 (20130101) Original (OR) Class H01L 29/778 (20130101) H01L 29/872 (20130101) H01L 29/2003 (20130101)
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09991360 — Method for forming III-V semiconductor structures including aluminum-silicon nitride passivation

US 09991360	Shealy et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	James R. Shealy (Ithaca, New York); Richard Brown (Ithaca, New York)
ASSIGNEE(S)	CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	James R. Shealy (Ithaca, New York); Richard Brown (Ithaca, New York)
ABSTRACT	A method for fabricating a semiconductor structure includes forming a semiconductor layer over a substrate and forming an aluminum-silicon nitride layer upon the semiconductor layer. When the semiconductor layer in particular comprises a III-V semiconductor material such as a group III nitride semiconductor material or a gallium nitride semiconductor material, the aluminum-silicon nitride material provides a superior passivation in comparison with a silicon nitride material.
FILED	Monday, June 28, 2010
APPL NO	13/380150
ART UNIT	2822 — Semiconductors/Memory
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/4846 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/644 (20130101) C12N 9/6437 (20130101) Enzymes C12Y 304/21021 (20130101) C12Y 304/21022 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/318 (20130101) H01L 21/02145 (20130101) H01L 21/02271 (20130101) H01L 23/291 (20130101) H01L 23/3171 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/7787 (20130101) H01L 29/42316 (20130101) H01L 29/66462 (20130101) Original (OR) Class H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101)
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09991391 — Pristine and functionalized graphene materials

US 09991391	Dai et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Hongjie Dai (Cupertino, California); Xiaolin Li (Menlo Park, California); Xiaoming Sun (Beijing, China PRC)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Hongjie Dai (Cupertino, California); Xiaolin Li (Menlo Park, California); Xiaoming Sun (Beijing, China PRC)
ABSTRACT	Disclosed are dispersed graphene sheets, ribbons, graphene molecules and the like which are pristine in the plane, i.e., free of significant defects and chemical modifications such as oxidation. The materials could be functionalized at the edges. These materials are dispersed in solutions rather than in aggregated or insoluble forms as their parent starting materials. Also disclosed is a method comprising the steps of intercalating an insoluble graphitic material. The method may comprise exfoliating graphite and re-intercalating the resultant material with an acid composition, such as oleum, and a strong organic base such as tetrabutylammonium hydroxide in a solvent solution to form a homogenous suspension, which is then agitated to form dispersed graphene materials. The materials may be solubilized with a hydrophilic polymer and can be further manipulated by transfer into different solvents, formation of films, application to optical and electronic devices, and other applications. The materials are solubilized by functional groups mostly at the edges.
FILED	Friday, July 24, 2009
APPL NO	12/508754
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) C01B 32/22 (20170801) C01B 32/225 (20170801) C01B 2204/02 (20130101) C01B 2204/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/778 (20130101) H01L 29/1606 (20130101) H01L 29/78684 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115)
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09991407 — Process for creating high efficiency photovoltaic cells

US 09991407	Dutta
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Achyut Kumar Dutta (Sunnyvale, California)
ASSIGNEE(S)	Banpil Photonics Inc. (Santa Clara, California)
INVENTOR(S)	Achyut Kumar Dutta (Sunnyvale, California)
ABSTRACT	A novel method to fabricate the high-efficiency solar cells are provided by this application. The cells are based on micro (or nano) structures that not only increase the surface area but also have the capability of self-concentrating the solar spectrum incident onto the cell. These photovoltaic cells have a larger power generation capability per unit physical area than conventional cells. These cells will have enormous applications in space, commercial, residential and industrial sectors.
FILED	Tuesday, June 22, 2010
APPL NO	12/821125
ART UNIT	2823 — Miscellaneous Articles, Stock Material
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/072 (20130101) Original (OR) Class H01L 31/0236 (20130101) H01L 31/0352 (20130101)
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09991512 — Thermally conductive lithium ion electrodes and batteries

US 09991512	Shevchenko et al.
FUNDED BY	Department of Defense (DOD) Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Elena Shevchenko (Riverside, Illinois); Anirudha V. Sumant (Plainfield, Illinois); Alexander Balandin (Riverside, California); Bonil Koo (Walnut Creek, California); Christopher Johnson (Naperville, Illinois); Tijana Rajh (Naperville, Illinois); Eungje Lee (Naperville, Illinois)
ABSTRACT	A thermally conductive electrochemical cell comprises a lithium ion-containing liquid electrolyte contacting a cathode and anode. The cathode and anode are in the form of electroactive sheets separated from each other by a membrane that is permeable to the electrolyte. One or more of the cathode and anode comprises two or more layers of carbon nanotubes, one of which layers includes electrochemically active nanoparticles and/or microparticles disposed therein or deposited on the nanotubes thereof. The majority of the carbon nanotubes in each of the layers are oriented generally parallel to the layers. Optionally, one or more of the layers includes an additional carbon material such as graphene, nanoparticulate diamond, microparticulate diamond, and a combination thereof.
FILED	Thursday, July 02, 2015
APPL NO	14/790449
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 10/052 (20130101)
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09991545 — Metal-air flow batteries using oxygen enriched electrolyte

US 09991545	Zheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Communications-Electronics Research, Development and Engineering Center (CERDEC) Department of Energy (DOE)
APPLICANT(S)	FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
ASSIGNEE(S)	FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
INVENTOR(S)	Jian-ping Zheng (Tallahassee, Florida); Petru Andrei (Tallahassee, Florida); Annadanesh Shellikeri (Tallahassee, Florida); Xujie Chen (Tallahassee, Florida)
ABSTRACT	A metal air flow battery includes an electrochemical reaction unit and an oxygen exchange unit. The electrochemical reaction unit includes an anode electrode, a cathode electrode, and an ionic conductive membrane between the anode and the cathode, an anode electrolyte, and a cathode electrolyte. The oxygen exchange unit contacts the cathode electrolyte with oxygen separate from the electrochemical reaction unit. At least one pump is provided for pumping cathode electrolyte between the electrochemical reaction unit and the oxygen exchange unit. A method for producing an electrical current is also disclosed.
FILED	Wednesday, June 28, 2017
APPL NO	15/635777
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/96 (20130101) H01M 4/382 (20130101) H01M 8/20 (20130101) Original (OR) Class H01M 8/04276 (20130101) H01M 12/08 (20130101) H01M 2300/0002 (20130101) H01M 2300/0037 (20130101)
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09991562 — Symmetrical and unsymmetrical organosilicon molecules and electrolyte compositions and electrochemical devices containing them

US 09991562	Hamers et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Warfare Center (NAWC)
APPLICANT(S)	Silatronix, Inc. (Madison, Wisconsin)
ASSIGNEE(S)	Silatronix, Inc. (Madison, Wisconsin)
INVENTOR(S)	Robert J Hamers (Madison, Wisconsin); Robert C West (Madison, Wisconsin); José A Peña Hueso (Madison, Wisconsin); Monica L Usrey (Madison, Wisconsin); Jian Dong (Fort Collins, Colorado)
ABSTRACT	Described are organosilicon electrolyte compositions having improved thermostability and electrochemical properties and electrochemical devices that contain the organosilicon electrolyte compositions.
FILED	Friday, September 06, 2013
APPL NO	14/426531
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2300/0037 (20130101)
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09991578 — Systems and methods for mode suppression in a cavity

US 09991578	Rogers
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	Shawn David Rogers (Johns Creek, Georgia)
ABSTRACT	Systems and methods for mode suppression in a cavity are provided. In certain implementations, an apparatus comprises a cavity for propagating electromagnetic signals therein, wherein the electromagnetic signals propagate multiple times through the cavity; and an absorbing material applied to a first side of the cavity, wherein the absorbing material absorbs the electromagnetic signals. Further, an apparatus includes at least one transmitting antenna configured to couple electromagnetic energy into the cavity; and at least one receiving antenna configured to couple electromagnetic energy from the cavity.
FILED	Tuesday, October 20, 2015
APPL NO	14/918416
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/162 (20130101) H01P 3/12 (20130101) H01P 3/122 (20130101) H01P 3/127 (20130101) Original (OR) Class H01P 7/06 (20130101) Antennas, i.e Radio Aerials H01Q 17/00 (20130101)
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09991605 — Frequency-scaled ultra-wide spectrum element

US 09991605	Elsallal et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The MITRE Corporation (McLean, Virginia); The United States of America, as Represented By The Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	THE MITRE CORPORATION (McLean, Virginia); The United States of America, as Rep. by the Sec. of Navy (Washington, District of Columbia)
INVENTOR(S)	Wajih Elsallal (Acton, Massachusetts); Jamie Hood (Owatonna, Minnesota); Al Locker (Westford, Massachusetts); Rick Kindt (Arlington, Virginia)
ABSTRACT	An antenna element including a base plate, a first ground clustered pillar projecting from the base plate, a second ground clustered pillar projecting from the base plate and spaced apart from a first side of the first ground clustered pillar, a first ground member projecting from the base plate between the first ground clustered pillar and the second ground clustered pillar, wherein a distal end of the first ground member is configured to capacitively couple to the second ground clustered pillar, and a first signal member projecting from the base plate between the first ground clustered pillar and the first ground member, wherein the first signal member is electrically insulated from the base plate, the first ground clustered pillar, and the first ground member, and a distal end of the first signal member is configured to capacitively couple to the first ground clustered pillar.
FILED	Tuesday, June 16, 2015
APPL NO	14/544934
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 3/30 (20130101) H01Q 13/085 (20130101) H01Q 21/24 (20130101) H01Q 21/062 (20130101) H01Q 21/064 (20130101) Original (OR) Class
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09991678 — Dispersion compensated diffractive optical element beam combiner

US 09991678	Thielen et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
ASSIGNEE(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S)	Peter A. Thielen (Long Beach, California); William H. Long, Jr. (Torrance, California); Eric C. Cheung (Torrance, California); Gregory D. Goodno (Los Angeles, California)
ABSTRACT	An optical system, such as a fiber laser amplifier, including a plurality of optical sources, such as fiber amplifiers, each generating a beam. In one embodiment, the system includes first and second diffraction gratings that correct the angle of the propagation direction of the beams to remove angular dispersion caused by a diffractive optical element (DOE). In another embodiment, the system includes a single diffraction grating, where the optical beams pass through the grating twice to also remove the angular dispersion caused by the DOE.
FILED	Tuesday, June 09, 2015
APPL NO	14/734959
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0812 (20130101) H01S 3/0826 (20130101) H01S 3/1055 (20130101) H01S 3/1305 (20130101) H01S 3/2308 (20130101) H01S 3/06754 (20130101) H01S 3/08009 (20130101) H01S 3/10007 (20130101) H01S 3/10023 (20130101) H01S 5/143 (20130101) H01S 5/4012 (20130101) Original (OR) Class
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09991837 — Systems and methods for vibration and noise manipulation in switched reluctance machine drivetrains

US 09991837	Vaks et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Continuous Solutions LLC (Portland, Oregon)
ASSIGNEE(S)	Continuous Solutions LLC (Portland, Oregon)
INVENTOR(S)	Nir Vaks (Portland, Oregon); Nyah Zarate (Portland, Oregon); Xiaoqi Wang (Portland, Oregon)
ABSTRACT	Systems and methods to manipulate the noise and vibration of a switched reluctance machine (SRM), capable of being implemented in a controller. By use of vibration sensors and a real-time optimizer, the noise and vibration profile of an SRM and associated load can be modified in order to meet multiple control objectives, such as torque ripple mitigation (TRM), harmonic spectrum shaping, and efficiency improvement. The systems and methods can be adapted to high power, high pole count, and high speed applications, and applications where electrical or mechanical imbalance exists.
FILED	Monday, May 22, 2017
APPL NO	15/601823
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 25/086 (20130101) H02P 25/092 (20160201) H02P 25/098 (20160201) Original (OR) Class
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09991863 — Rounded and curved integrated tethers for quartz resonators

US 09991863	Kubena et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	HRL LABORATORIES LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Randall L. Kubena (Oak Park, California); Deborah J. Kirby (Calabasas, California); David T. Chang (Calabasas, California)
ABSTRACT	A piezoelectric quartz shear-mode resonator includes plasma etched quartz tethers, each including a mount. The tethers are for mounting the resonator to a semiconductor substrate for the purpose of isolating the thermally-induced stress from the mounts from the active resonating region, wherein the quartz tethers have rounded corners.
FILED	Tuesday, April 07, 2015
APPL NO	14/680902
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/0076 (20130101) Original (OR) Class H03H 9/19 (20130101) H03H 2003/027 (20130101)
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09991874 — 8GHz-20GHz noise cancelling transversal reconfigurable notch filter

US 09991874	LaRocca et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
ASSIGNEE(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S)	Timothy R. LaRocca (Torrance, California); Denpol Kultran (Torrance, California)
ABSTRACT	A tunable analog noise-cancelling transversal reconfigurable filter for filtering an RF signal. The filter includes a noise-cancelling balun responsive to the RF signal and providing gain and noise suppression, and a time delay network responsive to the signal from the balun. The time delay network includes a single continuous three-dimensional air coaxial line where a separate tap is provided between sections of the line. The filter also includes a multiplication and summing network having a plurality of multiplication stages, where each stage is fed by a voltage signal from at least one of the taps, and each stage includes a multiplication amplifier that amplifies the voltage signal. A tuning element provides a multiplication coefficient to the amplified signal. Each amplified signal in each stage is added on an output line, where the multiplication and summing network operates under Millman's Theorem.
FILED	Wednesday, November 02, 2016
APPL NO	15/341829
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Impedance Networks, e.g Resonant Circuits; Resonators H03H 11/26 (20130101) H03H 11/32 (20130101) H03H 11/0427 (20130101) Original (OR) Class H03H 2011/0488 (20130101)
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09991968 — Devices and methods for electromagnetic signal phase discrimination using SQUID arrays and electro-optical materials

US 09991968	Taylor et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Benjamin J. Taylor (Escondido, California); Anna M. Leese de Escobar (Encinitas, California); Susan Anne Elizabeth Berggren (San Diego, California)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin J. Taylor (Escondido, California); Anna M. Leese de Escobar (Encinitas, California); Susan Anne Elizabeth Berggren (San Diego, California)
ABSTRACT	An electromagnetic signal is received at first and second Superconducting Quantum Interference Device (SQUID) SQUID arrays. The first and second SQUID arrays output respective voltage signals corresponding to the electromagnetic signal as received at the first and second SQUID arrays. The first and second SQUID arrays are spaced apart such that there is a phase difference between the electromagnetic signal as received at the first and second SQUID arrays. The phase difference results in a voltage amplitude difference. At least one of the voltage signals is applied to at least one reference optical signal input into an electro-optical device to modify the reference optical signal. The modified optical signal output by the electro-optical device includes a change compared to the reference optical signal. The change is indicative of the phase difference in the electromagnetic signal as received at the first and second SQUID arrays.
FILED	Wednesday, May 24, 2017
APPL NO	15/604035
ART UNIT	2637 — Optical Communications
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/21 (20130101) G02F 2001/212 (20130101) Transmission H04B 10/69 (20130101) Original (OR) Class
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09992048 — Systems and methods for detecting unused communication spectrum

US 09992048	Hu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama)
ASSIGNEE(S)	The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama)
INVENTOR(S)	Fei Hu (Tuscalossa, Alabama); Mengcheng Guo (Sunnyvale, California)
ABSTRACT	Systems and methods for cognitive radio spectrum sensing of a signal are disclosed herein. On exemplary method comprises applying a pre-defined cyclostationary feature to detect the presence of the signal; detecting the signal; detecting a spectrum associated with the signal; sampling randomly the detected signal from its cyclic frequency domain; and applying a compressive sensing algorithm to classify the signal based on the cyclostationary feature. The signal can be sparse in time, space, frequency, or code domains. Thereby, the systems and methods described in the present disclosure involve exploiting compressive sensing in a specific sparse domain (i.e., cyclic domain) and also utilize a cyclostationary feature based compressive spectrum sensing scheme to perform spectrum analysis.
FILED	Friday, April 01, 2016
APPL NO	15/088431
ART UNIT	2632 — Digital Communications
CURRENT CPC	Transmission H04B 1/7103 (20130101) H04B 2201/692 (20130101) H04B 2201/709709 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/0006 (20130101) Original (OR) Class
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09992057 — Yield tolerance in a neurosynaptic system

US 09992057	Alvarez-Icaza Rivera et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Rodrigo Alvarez-Icaza Rivera (San Jose, California); John V. Arthur (Mountain View, California); Andrew S. Cassidy (San Jose, California); Bryan L. Jackson (Fremont, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California); Jun Sawada (Austin, Texas)
ABSTRACT	Embodiments of the invention provide a neurosynaptic network circuit comprising multiple neurosynaptic devices including a plurality of neurosynaptic core circuits for processing one or more data packets. The neurosynaptic devices further include a routing system for routing the data packets between the core circuits. At least one of the neurosynaptic devices is faulty. The routing system is configured for selectively bypassing each faulty neurosynaptic device when processing and routing the data packets.
FILED	Friday, April 25, 2014
APPL NO	14/262592
ART UNIT	2465 — Multiplex and VoIP
CURRENT CPC	Electric Digital Data Processing G06F 11/00 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0659 (20130101) H04L 41/0668 (20130101) Original (OR) Class
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09992413 — Method and system for creating a display with a distributed aperture system

US 09992413	Hawkins
FUNDED BY	Department of Defense (DOD) Defense MicroElectronics Activity (DMEA)
APPLICANT(S)	Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Gregory S. Hawkins (Plano, Texas)
ABSTRACT	A method for displaying images captured by a distributed aperture system (DAS) includes determining a display line of sight (LOS) and display field of view (FOV) corresponding to an operator display of a DAS, mapping the display LOS and the display FOV to a set of sensors of a plurality of sensors of the DAS, for each sensor of the set of sensors: identifying a set of sensor elements that define a minimum image capture area corresponding to the display LOS and the display FOV, processing image data collected by the identified set of sensor elements; and generating an image for the operator display from the processed image data.
FILED	Friday, September 18, 2015
APPL NO	14/858101
ART UNIT	2485 — Recording and Compression
CURRENT CPC	Electric Digital Data Processing G06F 3/013 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 7/004 (20130101) G06T 7/0085 (20130101) G06T 15/20 (20130101) G06T 17/10 (20130101) G06T 2207/30244 (20130101) Pictorial Communication, e.g Television H04N 5/23238 (20130101) Original (OR) Class
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09992432 — Gain normalization and non-uniformity correction

US 09992432	Nazemi
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of the Navy (DON) Office of Naval Research (ONR) United States Marine Corps (USMC) Marine Corps Systems Command (MARCORSYSCOM)
APPLICANT(S)	Sensors Unlimited, Inc. (Princeton, New Jersey)
ASSIGNEE(S)	Sensors Unlimited, Inc. (Princeton, New Jersey)
INVENTOR(S)	Jonathan Nazemi (Doylestown, Pennsylvania)
ABSTRACT	A method of normalizing FPA system gain and correcting pixel non-uniformity for varying temperature includes determining an FPA temperature, calculating an FPA system gain as a function of the FPA temperature, and applying the FPA system gain at the FPA temperature to condition output of the FPA to produce temperature independent image data. The method also includes calculating a non-uniformity correction map on a pixel by pixel basis for the FPA, wherein non-uniformity correction for each pixel is a function of the FPA temperature, and applying the non-uniformity correction map to the imaging data from the FPA to produce temperature dependent non-uniformity corrected image data. An imaging system includes a focal plane array (FPA), a temperature sensor operatively connected to measure temperature of the FPA, and a module configured for system gain correction and non-uniformity correction as described above.
FILED	Monday, January 04, 2016
APPL NO	14/987372
ART UNIT	2482 — Recording and Compression
CURRENT CPC	Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 5/378 (20130101) H04N 5/3651 (20130101) H04N 5/3655 (20130101) Original (OR) Class
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09992867 — Cellulose and cellulosic substrate-based device

US 09992867	Lessing et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Multidisciplinary University Research Initiative (MURI) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Joshua Aaron Lessing (Cambridge, Massachusetts); Ana C. Glavan (Cambridge, Massachusetts); S. Brett Walker (Cambridge, Massachusetts); Christoph Matthias Keplinger (Cambridge, Massachusetts); George M. Whitesides (Newton, Massachusetts)
ABSTRACT	A cellulosic substrate-based device is described, including a cellulosic substrate comprising a functionalized surface covalently functionalized by a chemical moiety in an amount sufficient to provide an omniphobic or hydrophobic surface; and a material printed on the functionalized surface, wherein the printed material has a line edge roughness of less than about 15 μm and/or a line lateral resolution of less than about 50 μm.
FILED	Monday, April 13, 2015
APPL NO	15/301501
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/52 (20130101) Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 21/16 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0386 (20130101) Original (OR) Class
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National Science Foundation (NSF)

09987219 — UV-resistant microbes and UV-blocking microbial extract

US 09987219	Cuero et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Department of Agriculture (USDA)
APPLICANT(S)	The Texas A and M University System (College Station, Texas); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S)	Raul G. Cuero (Cypress, Texas); David S. McKay (Friendswood, Texas)
ABSTRACT	The present disclosure relates to a composition including an extract from an Acidithiobacillus bacteria or a yeast extracted after exposure of the bacteria to UV radiation. The disclosure further relates to a method of preparing a UV-blocking composition by exposing a culture of Acidithiobacillus or yeast to UV radiation and extracting UV-blocking cellular material produced in response to the UV radiation from the Acidithiobacillus or yeast. The disclosure further relates to a method of protecting an item from UV radiation damage by extracting UV-blocking cellular material from Acidithiobacillus or yeast exposed to UV radiation and covering the item with the UV-blocking cellular material. The disclosure further relates to a UV-resistant yeast cell and a UV-resistant bacterial cell.
FILED	Thursday, August 31, 2017
APPL NO	15/692066
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/02 (20130101) A01N 63/04 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/99 (20130101) Original (OR) Class Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101)
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09987380 — Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same

US 09987380	Li et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Zibo Li (San Gabriel, California); Francois P. Gabbai (College Station, Texas); Peter S. Conti (Pasadena, California); Todd W. Hudnall (College Station, Texas); Tzu-Pin Lin (College Station, Texas); Shuanglong Liu (Alhambra, California); Chiun-Wei Huang (Alhambra, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Zibo Li (San Gabriel, California); Francois P. Gabbai (College Station, Texas); Peter S. Conti (Pasadena, California); Todd W. Hudnall (College Station, Texas); Tzu-Pin Lin (College Station, Texas); Shuanglong Liu (Alhambra, California); Chiun-Wei Huang (Alhambra, California)
ABSTRACT	A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof: wherein R₁-R₇may be independently selected from hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, X is selected from the group consisting of C and N; and A is selected of hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, alkyl, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, including phenyl and aminophenyl, and heteroaryl.
FILED	Friday, July 13, 2012
APPL NO	13/549309
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/0021 (20130101) A61K 51/00 (20130101) A61K 51/0423 (20130101) A61K 51/0446 (20130101) Original (OR) Class A61K 51/0455 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101)
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09987653 — Versatile process for precision nanoscale manufacturing

US 09987653	Sreenivasan et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Sidlgata V. Sreenivasan (Austin, Texas); Shrawan Singhal (Austin, Texas)
ABSTRACT	A method for depositing thin films using a nominally curved substrate. Drops of a pre-cursor liquid organic material are dispensed at a plurality of locations on a nominally curved substrate by one or more inkjets. A superstrate is brought down on the dispensed drops to close the gap between the superstrate and the substrate thereby allowing the drops to form a contiguous film captured between the substrate and the superstrate. A non-equilibrium transient state of the superstrate, the contiguous film and the substrate is enabled to occur after a duration of time. The contiguous film is then cured to solidify it into a solid. The solid is separated from the superstrate thereby leaving a polymer film on the substrate. In this manner, such a technique for film deposition has the film thickness range, resolution and variation required to be applicable for a broad spectrum of applications.
FILED	Friday, October 14, 2016
APPL NO	15/293884
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Apparatus for Applying Fluent Materials to Surfaces, in General B05C 5/0291 (20130101) Original (OR) Class B05C 11/028 (20130101) B05C 13/00 (20130101) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/01 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/0038 (20130101)
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09987682 — Devices and methods for three-dimensional printing

US 09987682	Torabi et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	3DEO, Inc. (Gardena, California)
ASSIGNEE(S)	3DEO, Inc. (Gardena, California)
INVENTOR(S)	Payman Torabi (Los Angeles, California); Matthew Petros (Tarzana, California)
ABSTRACT	The present disclosure provides systems and methods for the formation of three-dimensional objects. A method for forming a three-dimensional object may comprise alternately and sequentially applying a stream comprising a binding substance to an area of a layer of powder material in a powder bed, and generating at least one perimeter of the three-dimensional object in the area. The stream may be applied in accordance with a model design of the three-dimensional object. The at least one perimeter may generated in accordance with the model design.
FILED	Thursday, August 03, 2017
APPL NO	15/668618
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/008 (20130101) Original (OR) Class B22F 3/24 (20130101) B22F 2003/247 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/00 (20141201)
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09987818 — Center-side method of producing superhydrophobic surface

US 09987818	Lyons et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S)	Research Foundation of the City University of New York (New York, New York)
INVENTOR(S)	Alan M. Lyons (New Providence, New Jersey); QianFeng Xu (Staten Island, New York)
ABSTRACT	A method for forming a superhydrophobic surface is disclosed. A surface of a first substrate is bonded to a surface of a second substrate to form a stacked material. The stacked material is peeled apart to form a fracture line and provide a superhydrophobic surface.
FILED	Friday, January 16, 2015
APPL NO	15/112307
ART UNIT	1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) Original (OR) Class B32B 3/266 (20130101) B32B 7/06 (20130101) B32B 27/08 (20130101) B32B 27/322 (20130101) B32B 37/025 (20130101) B32B 2255/10 (20130101) B32B 2255/20 (20130101) B32B 2307/73 (20130101) B32B 2307/412 (20130101) B32B 2307/416 (20130101) B32B 2307/538 (20130101) B32B 2307/704 (20130101) B32B 2551/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/00 (20130101)
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09988271 — Method of preparing carbon fibers

US 09988271	Lozano et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	Karen Lozano (Edinburg, Texas); Lee Daniel Cremar (McAllen, Texas)
ABSTRACT	A method of producing carbon fiber, yarns, and nonwoven carbon fiber cloths, includes forming suitable polymeric precursor microfibers and/or nanofibers using a centrifugal spinning process and decomposing at least a portion of the polymeric precursor fibers to form carbon fibers. The decomposition may be accomplished by treating the polymeric precursor fibers with acid vapor from an aqueous acid solution at a temperature of less than 250° C.
FILED	Monday, December 01, 2014
APPL NO	14/557080
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 31/00 (20130101) Original (OR) Class C01B 32/05 (20170801) C01B 32/15 (20170801) C01B 32/30 (20170801) C01B 32/312 (20170801) C01B 32/342 (20170801) C01B 32/354 (20170801) C01B 32/382 (20170801) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/18 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/14 (20130101) D01F 9/14 (20130101) D01F 11/06 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/72 (20130101) D04H 1/4242 (20130101) Technical Subjects Covered by Former US Classification Y10T 442/60 (20150401)
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09988393 — Isosorbide-based polymethacrylates

US 09988393	Hillmyer et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Marc A. Hillmyer (Minneapolis, Minnesota); Theresa Reineke (Vadnais Heights, Minnesota); James Gallagher (Minneapolis, Minnesota)
ABSTRACT	A monomer comprises the structure wherein R¹comprises H or a substituted hydrocarbyl or unsubstituted hydrocarbyl, and wherein R²comprises H, a halide, or a substituted or unsubstituted (C₁-C₄) hydrocarbyl. A method comprises (a) reacting a dianhydrohexitol precursor having the structure with an acyl-group containing compound having the structure wherein R¹comprises H or a substituted hydrocarbyl or unsubstituted hydrocarbyl, and X comprises a halide, a hydroxyl group, or an acyl group to form an acylated dianhydrohexitol ester intermediate having the structure and (b) reacting the acylated dianhydrohexitol ester intermediate with an acrylic-based compound having the structure wherein R²comprises H, a halide, or a substituted or unsubstituted (C₁-C₄) hydrocarbyl, and Y comprises a halide, a hydroxyl group, or an acyl group, to form a dianhydrohexitol-based monomer having the structure
FILED	Tuesday, February 09, 2016
APPL NO	15/019777
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Heterocyclic Compounds C07D 493/04 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 120/28 (20130101) C08F 220/28 (20130101) C08F 293/00 (20130101) C08F 2220/283 (20130101) C08F 2220/1825 (20130101) C08F 2438/03 (20130101)
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09988492 — Methods for post-fabrication functionalization of poly(ester ureas)

US 09988492	Becker et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Matthew Becker (Stow, Ohio); Fei Lin (Akron, Ohio)
ASSIGNEE(S)	The University of Akron (Akron, Ohio)
INVENTOR(S)	Matthew Becker (Stow, Ohio); Fei Lin (Akron, Ohio)
ABSTRACT	Amino acid-based poly(ester urea)s (PEU) are emerging as a class of polymers that have shown promise in regenerative medicine applications. Embodiments of the invention relate to the synthesis of PEUs carrying pendent “clickable” groups on modified tyrosine amino acids. The pendent species include alkyne, azide, alkene, tyrosine-phenol, and ketone groups. PEUs with M_wexceeding 100k Da were obtained via interfacial polycondensation methods and the concentration of pendent groups was varied by copolymerization. The incorporation of derivatizable functionalities is demonstrated using ¹H NMR and UV-Vis spectroscopy methods. Electrospinning was used to fabricate PEU nanofibers with a diameters ranging from 350 nm to 500 nm. The nanofiber matricies possess mechanical strengths suitable for tissue engineering (Young's modulus: 300±45 MPa; tensile stress: 8.5±1.2 MPa). A series of bioactive peptides and fluorescent molecules were conjugated to the surface of the nanofibers following electrospinning using bio-orthogonal reactions in aqueous media.
FILED	Tuesday, September 30, 2014
APPL NO	15/026069
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 227/18 (20130101) C07C 229/34 (20130101) C07C 247/04 (20130101) C07C 275/16 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 71/02 (20130101) Original (OR) Class C08G 2230/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/02 (20130101)
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09988653 — Method and apparatus for CO₂sequestration

US 09988653	Subhas et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California); Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (Jerusalem, Israel)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California); Yissum Research Development Company of the Hebrew University of Jeresalem Ltd. (Jerusalam, Israel)
INVENTOR(S)	Adam Vinay Subhas (Los Angeles, California); William Berelson (Los Angeles, California); Nick Everett Rollins (Santa Monica, California); Jess Firey Adkins (Altadena, California); Jonathan Erez (Jerusalem, Israel)
ABSTRACT	Processes, methods, and apparatus for carbon sequestration utilizing catalysis schemes configured to provide high concentrations of hydrated CO₂in proximity with a sequestration agent are provided. Reactants are combined with catalyst such that at least two regions of controlled catalytic activity form encompassing at least the interface between a sequestration agent and an aqueous solution containing dissolved CO₂. Suitable reactants include various sequestration agents, catalyst, and carbon dioxide dissolved in an aqueous solution (seawater, for example). Possible products include bicarbonate and metal cations.
FILED	Friday, December 18, 2015
APPL NO	14/975584
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/62 (20130101) B01D 53/77 (20130101) B01D 53/346 (20130101) B01D 53/8671 (20130101) B01D 2251/90 (20130101) B01D 2251/606 (20130101) B01D 2255/804 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/58 (20130101) C12M 27/00 (20130101) C12M 29/00 (20130101) C12M 29/04 (20130101) C12M 29/18 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/40 (20130101) Original (OR) Class Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/59 (20151101) Y02P 20/152 (20151101)
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09988667 — Device and methods for epigenetic analysis

US 09988667	Craighead et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) National Science Foundation (NSF)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Harold G. Craighead (Ithaca, New York); Benjamin R. Cipriany (Ithaca, New York); Stephen Levy (Ithaca, New York); Paul Soloway (Ithaca, New York)
ABSTRACT	Provided herein are methods and devices for single object detection. The methods and devices can be used to identify a plurality of epigenetic markers on a genetic material, or a chromatin, encompassing fragments thereof. The invention provides for the characterization of the genetic material flowing through a channel in a continuous body of fluid based on detection of one or more properties of the genetic material. The methods and systems provided herein allow genome-wide, high-throughput epigenetic analysis and overcome a variety of limitations common to bulk analysis techniques.
FILED	Friday, August 26, 2016
APPL NO	15/249275
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0663 (20130101) B01L 2300/0654 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2561/113 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101)
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09988677 — DNA/RNA sequencing using a semiconducting nanopore

US 09988677	Fleharty et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Mark Fleharty (Albuquerque, New Mexico); Dimiter N. Petsev (Albuquerque, New Mexico); Frank B. Van Swol (Tijeras, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Mark Fleharty (Albuquerque, New Mexico); Dimiter N. Petsev (Albuquerque, New Mexico); Frank B. Van Swol (Tijeras, New Mexico)
ABSTRACT	The present disclosure provides novel apparatus including, though not necessarily limited to, biosensors utilizing semiconductor materials in electrolyte solutions and methods for using the same. The biosensors rely on a unique property wherein a charged body in the electrolyte solution produces a detectable change in the local conductivity of the semiconductor as the body approaches or travels near the semiconductor.
FILED	Wednesday, June 10, 2015
APPL NO	14/735898
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3278 (20130101) G01N 33/48721 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/24 (20130101)
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09989043 — System and method for processor-based security

US 09989043	Lee et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Teleputers, LLC (Princeton, New Jersey)
ASSIGNEE(S)	Teleputers, LLC (Princeton, New Jersey)
INVENTOR(S)	Ruby B. Lee (Princeton, New Jersey); David Champagne (London, United Kingdom)
ABSTRACT	A system and method for processor-based security is provided, for on-chip security and trusted computing services for software applications. A processor is provided having a processor core, a cache memory, a plurality of registers for storing at least one hash value and at least one encryption key, a memory interface, and at least one on-chip instruction for creating a secure memory area in a memory external to the processor, and a hypervisor program executed by the processor. The hypervisor program instructs the processor to execute the at least one on-chip instruction to create a secure memory area for a software area for a software module, and the processor encrypts data written to, and decrypts data read from, the external memory using the at least one encryption key and the verifying data read from the external memory using the at least one hash value.
FILED	Tuesday, October 10, 2017
APPL NO	15/729401
ART UNIT	2497 — Cryptography and Security
CURRENT CPC	Positive-displacement Machines for Liquids; Pumps F04B 33/00 (20130101) Original (OR) Class Electric Digital Data Processing G06F 21/57 (20130101) G06F 21/72 (20130101) G06F 21/575 (20130101)
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09989412 — Low-noise spectroscopic imaging system

US 09989412	Rowlette et al.
FUNDED BY	National Science Foundation (NSF) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Daylight Solutions, Inc. (San Diego, California)
ASSIGNEE(S)	DAYLIGHT SOLUTIONS, INC. (San Diego, California)
INVENTOR(S)	Jeremy Rowlette (Escondido, California); Edeline Fotheringham (San Diego, California); William Chapman (San Diego, California); Miles Weida (Poway, California); David Arnone (Mountain View, California)
ABSTRACT	A spectral imaging device (12) includes an image sensor (28), an illumination source (14), a refractive, optical element (24A), a mover assembly (24C) (29), and a control system (30). The image sensor (28) acquires data to construct a two-dimensional spectral image (13A) during a data acquisition time (346). The illumination source (14) generates an illumination beam (16) that illuminates the sample (10) to create a modified beam (16I) that follow a beam path (16B) from the sample (10) to the image sensor (28). The refractive, optical element (24A) is spaced apart a separation distance (42) from the sample (10) along the beam path (16B). During the data acquisition time (346), the control system (30) controls the illumination source (14) to generate the illumination beam (16), controls the mover assembly (29) (24C) to modulate the separation distance (42), and controls the image sensor (28) to capture the data.
FILED	Friday, March 25, 2016
APPL NO	15/081743
ART UNIT	2487 — Recording and Compression
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/08 (20130101) G01J 3/10 (20130101) G01J 3/32 (20130101) G01J 3/42 (20130101) G01J 3/0208 (20130101) Original (OR) Class G01J 3/0262 (20130101) G01J 3/0289 (20130101) G01J 3/2803 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) G01N 21/39 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/361 (20130101)
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09989451 — Method and system for measuring porosity of particles

US 09989451	Cheong et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S)	Fook Chiong Cheong (New York, New York); Ke Xiao (Elmhurst, New York); David Pine (New York, New York); David G. Grier (New York, New York)
ABSTRACT	A method for analyzing porosity of a particle and a medium disposed in the porosity of the particle. A video-holographic microscope is provided to analyze interference patterns produced by providing a laser source to output a collimated beam, scattering the collimated beam off a particle and interacting with an unscattered beam to generate the interference pattern for analyzation to determine the refractive index of the particle and a medium disposed in the porosity of the particle to measure porosity and the medium.
FILED	Monday, December 12, 2016
APPL NO	15/376274
ART UNIT	2484 — Recording and Compression
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/088 (20130101) Original (OR) Class G01N 15/1463 (20130101) G01N 21/453 (20130101) G01N 2015/0846 (20130101) Optical Elements, Systems, or Apparatus G02B 21/367 (20130101)
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09989452 — Magnetohydrodynamic microfluidic systems including modified electrodes and methods of using the same

US 09989452	Fritsch et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S)
INVENTOR(S)	Ingrid Fritsch (Fayetteville, Arkansas); Christena Nash (Roswell, Georgia); Sai Kumar (Johns Creek, Georgia); Timothy Muldoon (Fayetteville, Arkansas); Kartik Balachandran (Fayetteville, Arkansas); Adair Claycomb (Arlington, Texas); Matthew D. Gerner (Fayetteville, Arkansas); Joshua Hutcheson (Fayetteville, Arkansas); Foysal Z. Khan (Fayetteville, Arkansas); Amy Powless (Rogers, Arkansas); Sandra Prieto (Siloam Springs, Arkansas); Preston G. Scrape (Jonesboro, Arkansas); Melissa C. Weston (Duncan, Oklahoma)
ABSTRACT	A magnetohydrodynamic microfluidic system and a method of pumping a fluid using a magnetohydrodynamic system are disclosed. The method includes applying at least one of an electric current and an electric voltage to a first modified electrode and a second electrode to generate an ionic current between the first modified electrode and the second electrode and to cause a current carrying species to move to or from the modified electrode, applying a magnetic field perpendicular to an ionic current vector, the magnetic field and the ionic current combining to induce flow of the fluid in a direction perpendicular to the magnetic field and the ionic current vector, and maintaining fluid flow by recharging the modified electrode.
FILED	Tuesday, November 24, 2015
APPL NO	14/951322
ART UNIT	1756 — Recording and Compression
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 13/0077 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2400/043 (20130101) B01L 2400/0415 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 19/006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) G01N 15/1475 (20130101) Original (OR) Class G01N 27/447 (20130101) G01N 2015/008 (20130101) G01N 2015/1486 (20130101)
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09989471 — Device for spectroscopic detection and monitoring of biologically relevant molecules

US 09989471	Marks et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF)
APPLICANT(S)	The Texas A and M University System (College Station, Texas)
ASSIGNEE(S)	The Texas A and M University System (College Station, Texas)
INVENTOR(S)	Haley L. Marks (Brighton, Massachusetts); Gerard L. Coté (College Station, Texas); Mitchell B. Robinson (Willow Park, Texas); Po-Jung Huang (College Station, Texas); Jun Kameoka (College Station, Texas)
ABSTRACT	There is a need in the point-of-care diagnostic community for an efficient and portable method for testing blood and other biological fluids that can be easily translated across multiple applications. An aspect of the invention described involves monitoring the optical properties of molecularly-mediated nanoparticle assemblies though an optically transparent and magnetically active microfluidic chip, which has recently emerged as an attractive method for biomarker detection as it is an efficient tool for monitoring the binding events that take place in a sensing assay. In one embodiment, this device is directed towards two-nanoparticle assays that rely on the assembly or disassembly of plasmonic and magnetic nanoparticles in response to a certain analyte. A further embodiment is directed to a spiral microfluidic using inertial forces to filter fluid components by size, connected to a magnetically active channel comprised of a nickel micropad array, optically transparent microchannel, and permanent magnets.
FILED	Monday, February 13, 2017
APPL NO	15/431604
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 21/658 (20130101) Original (OR) Class G01N 2021/651 (20130101)
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09989534 — Systems and methods for high throughput analysis of conformation in biological entities

US 09989534	Salafsky et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Biodesy, Inc. (South San Francisco, California)
ASSIGNEE(S)	BIODESY, INC. (South San Francisco, California)
INVENTOR(S)	Joshua Salafsky (San Francisco, California); Louis J. Dietz (Mountain View, California); Ray Hebert (Florence, Oregon); Dar Bahatt (Foster City, California)
ABSTRACT	Methods, devices, and systems are disclosed for performing high throughput analysis of conformational change in biological molecules or other biological entities using surface-selective nonlinear optical detection techniques.
FILED	Monday, June 29, 2015
APPL NO	14/754465
ART UNIT	1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 3/502715 (20130101) B01L 2300/0636 (20130101) B01L 2300/0819 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/552 (20130101) G01N 21/636 (20130101) G01N 33/6845 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 5/045 (20130101)
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09989677 — Ultra-thin, planar, plasmonic metadevices

US 09989677	Shalaev et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Air Force Research Laboratory (AFRL) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S)	Vladimir Shalaev (West Lafayette, Indiana); Alexander Kildishev (West Lafayette, Indiana); Xingjie Ni (West Lafayette, Indiana); Satoshi Ishii (Hyogo, Japan)
ABSTRACT	An ultra-thin planar device is used for arbitrary waveform formation on a micrometer scale, regardless of the incident light's polarization. Patterned perforations are made in a 30 nm-thick metal film, creating discrete phase shifts and forming a desired wavefront of cross-polarized, scattered light. The signal-to-noise ratio of these devices is at least one order of magnitude higher than current metallic nano-antenna designs. The focal length of a lens built on such principle can also be adjusted by changing the wavelength of the incident light. All proposed embodiments can be embedded, for example, on a chip or at the end of an optical fiber.
FILED	Wednesday, September 04, 2013
APPL NO	14/427052
ART UNIT	2872 — Optics
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/008 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/834 (20130101)
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09990337 — System and method for using data and angles to automatically generate a narrative story

US 09990337	Birnbaum et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Narrative Science Inc. (Chicago, Illinois)
ASSIGNEE(S)	NARRATIVE SCIENCE INC. (Chicago, Illinois)
INVENTOR(S)	Lawrence A. Birnbaum (Evanston, Illinois); Kristian J. Hammond (Chicago, Illinois); Nicholas D. Allen (Chicago, Illinois); John R. Templon (Chicago, Illinois)
ABSTRACT	A system and method for automatically generating a narrative story receives data and information pertaining to a domain event. The received data and information and/or one or more derived features are then used to identify a plurality of angles for the narrative story. The plurality of angles is then filtered, for example through use of parameters that specify a focus for the narrative story, length of the narrative story, etc. Points associated with the filtered plurality of angles are then assembled and the narrative story is rendered using the filtered plurality of angles and the assembled points.
FILED	Monday, July 31, 2017
APPL NO	15/664414
ART UNIT	2657 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Electric Digital Data Processing G06F 17/24 (20130101) G06F 17/27 (20130101) G06F 17/212 (20130101) Original (OR) Class G06F 17/2775 (20130101) G06F 17/30312 (20130101) G06F 17/30371 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101)
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09990856 — Systems and methods for providing vibration feedback in robotic systems

US 09990856	Kuchenbecker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Katherine J. Kuchenbecker (Philadelphia, Pennsylvania); Will McMahan (Philadelphia, Pennsylvania); Ernest D. Gomez (Philadelphia, Pennsylvania); Karlin Bark (Menlo Park, California)
ABSTRACT	Systems and methods for training an operator of a robotic surgery system are disclosed. One such method includes enabling the operator to perform a test procedure, recording vibrations of a surgical tool of the robotic surgery system during the test procedure, and generating a score for the operator based at least in part on the recorded vibrations of the surgical tool.
FILED	Friday, March 15, 2013
APPL NO	13/833122
ART UNIT	3715 — Amusement and Education Devices
CURRENT CPC	Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) Original (OR) Class G09B 23/285 (20130101)
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09991076 — Electromechanical device

US 09991076	Bulovic et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Vladimir Bulovic (Lexington, Massachusetts); Jeffrey H. Lang (Sudbury, Massachusetts); Hae-Seung Lee (Lexington, Massachusetts); Timothy M. Swager (Newton, Massachusetts); Trisha L. Andrew (Madison, Wisconsin); Matthew Eric D'Asaro (Cambridge, Massachusetts); Parag Deotare (Medford, Massachusetts); Apoorva Murarka (Cambridge, Massachusetts); Farnaz Niroui (Ontario, Canada); Ellen Sletten (Somerville, Massachusetts); Annie I-Jen Wang (Cambridge, Massachusetts)
ABSTRACT	Electromechanical devices described herein may employ tunneling phenomena to function as low-voltage switches. Opposing electrodes may be separated by an elastically deformable layer which, in some cases, may be made up of a non-electrically conductive material. In some embodiments, the elastically deformable layer is substantially free of electrically conductive material. When a sufficient actuation voltage and/or force is applied, the electrodes are brought toward one another and, accordingly, the elastically deformable layer is compressed. Though, the elastically deformable layer prevents the electrodes from making direct contact with one another. Rather, when the electrodes are close enough to one another, a tunneling current arises therebetween. The elastically deformable layer may exhibit spring-like behavior such that, upon release of the actuation voltage and/or force, the separation distance between electrodes is restored. Thus, the electromechanical device may be actuated between open and closed switch positions.
FILED	Tuesday, January 28, 2014
APPL NO	14/763681
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 49/00 (20130101) H01H 59/0009 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115)
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09991105 — Active stabilization of ion trap radiofrequency potentials

US 09991105	Monroe et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Physics (PHY)
APPLICANT(S)	University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S)
INVENTOR(S)	Christopher Monroe (Ellicott City, Maryland); Kale Johnson (Milford, Connecticut); Jaime David Wong-Campos (Hyattsville, Maryland)
ABSTRACT	Disclosed are improved methods and structures for actively stabilizing the oscillation frequency of a trapped ion by noninvasively sampling and rectifying the high voltage RF potential at circuit locations between a step-up transformer and a vacuum feedthrough leading to the ion trap electrodes. We use this sampled/rectified signal in a feedback loop to regulate the RF input amplitude to the circuit. By employing techniques and structures according to the present disclosure we are advantageously able to stabilize a 1 MHz trapped ion oscillation frequency to <10 Hz after 200 s of integration, representing a 34 dB reduction in the level of trap frequency noise and drift, over a locking bandwidth of up to 30 kHz.
FILED	Friday, December 23, 2016
APPL NO	15/389982
ART UNIT	2881 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/0027 (20130101) Original (OR) Class H01J 49/422 (20130101)
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09991444 — Surface-modified organic semiconductors

US 09991444	Ciszek et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	LOYOLA UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S)	LOYOLA UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S)	Jacob W. Ciszek (Glenview, Illinois); Brittni A. Qualizza (Chicago, Illinois); Srividya Prasad (Mount Pleasant, Michigan)
ABSTRACT	Surface-modified organic semiconductors and methods for making surface-modified organic semiconductors are disclosed. More particularly, surface-modified thin films are provided, the surface-modified thin films comprising a first layer comprising a polyaromatic organic semiconductor and a surface layer in direct contact with the first layer, the surface layer comprising an addition reaction product of the polyaromatic organic semiconductor with, for example, a dienophile, wherein the first layer is substantially free of the addition reaction product of the organic semiconductor with the dienophile. Also provided are surface-modified single crystals comprising a core comprising a polyaromatic organic semiconductor and a coating in direct contact with the core, the coating comprising, for example, an addition reaction product of the polyaromatic organic semiconductor with a dienophile, wherein the core is substantially free of the addition reaction product of the organic semiconductor with the dienophile.
FILED	Thursday, September 04, 2014
APPL NO	14/476901
ART UNIT	1788 — Miscellaneous Articles, Stock Material
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0052 (20130101) Original (OR) Class H01L 51/0054 (20130101) H01L 51/0055 (20130101) H01L 51/0056 (20130101) H01L 51/0071 (20130101) H01L 51/0558 (20130101)
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09991771 — Active control system for a variable electromotive-force generator with applications to wind turbines, ships, and hybrid vehicles

US 09991771	Zhu et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	University of Maryland, Baltimore County (Baltimore, Maryland)
ASSIGNEE(S)	THE UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland)
INVENTOR(S)	Weidong Zhu (Ellicott City, Maryland); Navid Goudarzi (Baltimore, Maryland); Xuefeng Wang (Halethorpe, Maryland)
ABSTRACT	This invention relates to an active control system for a variable electromotive-force generator (VEG) for use in wind turbines, ships, hybrid vehicles, and related applications.
FILED	Wednesday, November 05, 2014
APPL NO	14/534112
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 15/2009 (20130101) B60L 2220/50 (20130101) B60L 2240/421 (20130101) B60L 2240/423 (20130101) B60L 2270/145 (20130101) Wind Motors F03D 7/0272 (20130101) Dynamo-electric Machines H02K 7/1838 (20130101) H02K 21/024 (20130101) Original (OR) Class H02K 21/24 (20130101) H02K 2201/03 (20130101) H02K 2213/09 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/723 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/641 (20130101) Y02T 10/645 (20130101) Y02T 10/7275 (20130101)
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09992038 — Underwater multi-hop communications network

US 09992038	Youngbull et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Cody Youngbull (Tempe, Arizona); David Ganger (Chandler, Arizona); Andres Mora (Tempe, Arizona); Andrea Richa (Tempe, Arizona); Jin Zhang (Kirkland, Washington); Chenyang Zhou (Tempe, Arizona); Xinhui Hu (Tempe, Arizona)
ABSTRACT	A multi-hop ad hoc communications network may allow optical communications between underwater nodes. Each node may be fitted with environmental sensors. Each node may collect data from the sensors and transmit the data to other nodes in the network according to a time division multiple access (TDMA) scheme. The data may propagate through a series of child and parent nodes to reach a master node. The master node may have a wired connection for power and data transfer.
FILED	Friday, June 13, 2014
APPL NO	14/898440
ART UNIT	2478 — Multiplex and VoIP
CURRENT CPC	Transmission H04B 7/2643 (20130101) H04B 10/11 (20130101) H04B 13/02 (20130101) Multiplex Communication H04J 3/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/28 (20130101) H04L 12/4035 (20130101) Original (OR) Class H04L 45/16 (20130101) H04L 45/48 (20130101) Selecting H04Q 9/00 (20130101) H04Q 11/0062 (20130101) H04Q 2209/30 (20130101) Wireless Communication Networks H04W 76/046 (20130101) H04W 84/18 (20130101)
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09992217 — Methods, systems, and computer readable media for detecting malicious network traffic

US 09992217	Taylor et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Teryl Paul Taylor (Durham, North Carolina); Kevin Zachary Snow (Cary, North Carolina); Nathan Michael Otterness (Mebane, North Carolina); Fabian Newman Monrose (Chapel Hill, North Carolina)
ABSTRACT	Methods, systems, and computer readable media for detecting malicious network traffic are disclosed. According to one method, the method includes caching network traffic transmitted between a client and a server, wherein the network traffic includes a uniform resource locator (URL) for accessing at least one file from the server. The method also includes determining whether the at least one file is suspicious. The method further includes in response to determining that the at least one file is suspicious, determining whether the at least one file is malicious by replaying the network traffic using an emulated client and an emulated server.
FILED	Friday, December 30, 2016
APPL NO	15/396114
ART UNIT	2437 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 12/0813 (20130101) G06F 2212/60 (20130101) G06F 2212/62 (20130101) G06F 2212/154 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/08 (20130101) H04L 63/166 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 67/02 (20130101) H04L 67/2842 (20130101)
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09992222 — Systems and methods for inhibiting attacks with a network

US 09992222	Stavrou et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Angelos Stavrou (New York, New York); Angelos D. Keromytis (New York, New York)
ABSTRACT	Systems and methods for inhibiting attacks with a network are provided. In some embodiments, methods for inhibiting attacks by forwarding packets through a plurality of intermediate nodes when being transmitted from a source node to a destination node are provided, the methods comprising: receiving a packet at one of the plurality of intermediate nodes; determining at the selected intermediate node whether the packet has been sent to the correct one of the plurality of intermediate nodes based on a pseudo random function; and forwarding the packet to the destination node, based on the determining. In some embodiments an intermediate node is selected based on a pseudo random function. In some embodiments, systems and methods for establishing access to a multi-path network are provided.
FILED	Thursday, May 05, 2016
APPL NO	15/147441
ART UNIT	2435 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/12 (20130101) H04L 63/123 (20130101) H04L 63/0823 (20130101) H04L 63/1416 (20130101) H04L 63/1458 (20130101) Original (OR) Class H04L 2463/141 (20130101)
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09992867 — Cellulose and cellulosic substrate-based device

US 09992867	Lessing et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Multidisciplinary University Research Initiative (MURI) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Joshua Aaron Lessing (Cambridge, Massachusetts); Ana C. Glavan (Cambridge, Massachusetts); S. Brett Walker (Cambridge, Massachusetts); Christoph Matthias Keplinger (Cambridge, Massachusetts); George M. Whitesides (Newton, Massachusetts)
ABSTRACT	A cellulosic substrate-based device is described, including a cellulosic substrate comprising a functionalized surface covalently functionalized by a chemical moiety in an amount sufficient to provide an omniphobic or hydrophobic surface; and a material printed on the functionalized surface, wherein the printed material has a line edge roughness of less than about 15 μm and/or a line lateral resolution of less than about 50 μm.
FILED	Monday, April 13, 2015
APPL NO	15/301501
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/52 (20130101) Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 21/16 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0386 (20130101) Original (OR) Class
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Department of Energy (DOE)

09986924 — Implantable biomedical devices on bioresorbable substrates

US 09986924	Rogers et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Energy (DOE)
APPLICANT(S)	THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); Northwestern University (Evanston, Illinois); Trustees of Tufts College (Medford, Massachusetts); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	John A. Rogers (Champaign, Illinois); Dae-Hyeong Kim (Urbana, Illinois); Fiorenzo Omenetto (Wakefield, Massachusetts); David L. Kaplan (Concord, Massachusetts); Brian Litt (Bala Cynwyd, Pennsylvania); Jonathan Viventi (Philadelphia, Pennsylvania); Yonggang Huang (Glencoe, Illinois); Jason Amsden (Eddington, Maine)
ABSTRACT	Provided herein are implantable biomedical devices and methods of administering implantable biomedical devices, making implantable biomedical devices, and using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment.
FILED	Tuesday, December 24, 2013
APPL NO	14/140299
ART UNIT	3739 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/04 (20130101) Original (OR) Class A61B 5/05 (20130101) A61B 5/6867 (20130101) A61B 2562/0285 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/047 (20130101) A61L 31/148 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/0551 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101)
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09987380 — Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same

US 09987380	Li et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Zibo Li (San Gabriel, California); Francois P. Gabbai (College Station, Texas); Peter S. Conti (Pasadena, California); Todd W. Hudnall (College Station, Texas); Tzu-Pin Lin (College Station, Texas); Shuanglong Liu (Alhambra, California); Chiun-Wei Huang (Alhambra, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Zibo Li (San Gabriel, California); Francois P. Gabbai (College Station, Texas); Peter S. Conti (Pasadena, California); Todd W. Hudnall (College Station, Texas); Tzu-Pin Lin (College Station, Texas); Shuanglong Liu (Alhambra, California); Chiun-Wei Huang (Alhambra, California)
ABSTRACT	A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof: wherein R₁-R₇may be independently selected from hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, X is selected from the group consisting of C and N; and A is selected of hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, alkyl, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, including phenyl and aminophenyl, and heteroaryl.
FILED	Friday, July 13, 2012
APPL NO	13/549309
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/0021 (20130101) A61K 51/00 (20130101) A61K 51/0423 (20130101) A61K 51/0446 (20130101) Original (OR) Class A61K 51/0455 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101)
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09987427 — Diagnostic/drug delivery “sense-respond” devices, systems, and uses thereof

US 09987427	Polsky et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Ronen Polsky (Albuquerque, New Mexico); Philip Rocco Miller (Albuquerque, New Mexico); Thayne L. Edwards (Albuquerque, New Mexico)
ABSTRACT	The present invention is directed to devices, systems, and methods for detecting and/or monitoring one or more markers in a sample. In particular, such devices integrate a plurality of hollow needles configured to extract or obtain a fluid sample from a subject, as well as transducers to detect a marker of interest.
FILED	Monday, June 22, 2015
APPL NO	14/746301
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/157 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 37/0015 (20130101) A61M 2005/1726 (20130101) A61M 2037/0023 (20130101) A61M 2037/0061 (20130101) A61M 2202/30 (20130101) A61M 2202/048 (20130101)
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09987583 — Polymers functionalized with brønsted acid groups

US 09987583	Van Humbeck et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Jeffrey Van Humbeck (Watertown, Massachusetts); Jeffrey R. Long (Oakland, California); Thomas M. McDonald (Berkeley, California); Gokhan Barin (Albany, California)
ABSTRACT	Porous aromatic framework polymers functionalized with Brønsted acid moieties are prepared by polymerization of a three-dimensional organic aryl or heteroaryl monomer and its copolymerization with a second aryl or heteroaryl monomer functionalized with one or more Brønsted acid moiety. The polymers are characterized by a stable three-dimensional structure, which, in exemplary embodiments, includes interpenetrating subunits within one or more domain of the bulk polymer structure. The polymers are of use in methods of adsorbing ammonia and amines and in devices and systems configured for this purpose.
FILED	Friday, November 21, 2014
APPL NO	15/038286
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Separation B01D 53/02 (20130101) Original (OR) Class B01D 2253/202 (20130101) B01D 2257/406 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) B01J 20/261 (20130101) B01J 20/264 (20130101) B01J 20/3425 (20130101) B01J 20/3483 (20130101) B01J 20/3491 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/10 (20130101) C08G 77/00 (20130101) C08G 2261/72 (20130101) C08G 2261/80 (20130101) C08G 2261/143 (20130101) C08G 2261/312 (20130101) C08G 2261/1426 (20130101) C08G 2261/1452 (20130101)
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09987605 — Method for multi-axis, non-contact mixing of magnetic particle suspensions

US 09987605	Martin et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	James E. Martin (Tijeras, New Mexico); Kyle J. Solis (Rio Rancho, New Mexico)
ABSTRACT	Continuous, three-dimensional control of the vorticity vector is possible by progressively transitioning the field symmetry by applying or removing a dc bias along one of the principal axes of mutually orthogonal alternating fields. By exploiting this transition, the vorticity vector can be oriented in a wide range of directions that comprise all three spatial dimensions. Detuning one or more field components to create phase modulation causes the vorticity vector to trace out complex orbits of a wide variety, creating very robust multiaxial stirring. This multiaxial, non-contact stirring is particularly attractive for applications where the fluid volume has complex boundaries, or is congested.
FILED	Wednesday, December 02, 2015
APPL NO	14/957056
ART UNIT	1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/0057 (20130101) B01F 13/0809 (20130101) Original (OR) Class
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09987611 — Non-thermal plasma conversion of hydrocarbons

US 09987611	Strohm et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	H Quest Vanguard, Inc. (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	H Quest Vanguard, Inc. (Pittsburgh, Pennsylvania)
INVENTOR(S)	James J. Strohm (Allison Park, Pennsylvania); George L. Skoptsov (Pittsburgh, Pennsylvania); Evan T. Musselman (Pittsburgh, Pennsylvania); Kurt W. Zeller (Pittsburgh, Pennsylvania)
ABSTRACT	A non-thermal plasma is generated to selectively convert a precursor to a product. More specifically, plasma forming material and a precursor material are provided to a reaction zone of a vessel. The reaction zone is exposed to microwave radiation, including exposing the plasma forming material and the precursor material to the microwave radiation. The exposure of the plasma forming material to the microwave radiation selectively converts the plasma forming material to a non-thermal plasma including formation of one or more streamers. The precursor material is mixed with the plasma forming material and the precursor material is exposed to the non-thermal plasma including exposing the precursor material to the one or more streamers. The exposure of the precursor material to the streamers and the microwave radiation selectively converts the precursor material to a product.
FILED	Tuesday, August 08, 2017
APPL NO	15/671584
ART UNIT	1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/126 (20130101) Original (OR) Class B01J 2219/0875 (20130101) B01J 2219/0894 (20130101) B01J 2219/1206 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801)
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09987657 — Method for coating ultrafine particles, system for coating ultrafine particles

US 09987657	Li et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Jie Li (Darien, Illinois); Yung Liu (Hinsdale, Illinois)
ABSTRACT	The invention provides a method for dispersing particles within a reaction field, the method comprising confining the particles to the reaction field using a standing wave. The invention also provides a system for coating particles, the system comprising a reaction zone; a means for producing fluidized particles within the reaction zone; a fluid to produce a standing wave within the reaction zone; and a means for introducing coating moieties to the reaction zone. The invention also provides a method for coating particles, the method comprising fluidizing the particles, subjecting the particles to a standing wave; and contacting the subjected particles with a coating moiety.
FILED	Tuesday, December 23, 2014
APPL NO	14/581154
ART UNIT	1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/006 (20130101) B01J 2/16 (20130101) Apparatus for Applying Fluent Materials to Surfaces, in General B05C 19/02 (20130101) Original (OR) Class B05C 19/06 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/24 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/442 (20130101) C23C 16/4417 (20130101) C23C 16/45502 (20130101)
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09987699 — Electrochemical system and method for electropolishing hollow metal bodies

US 09987699	Taylor et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Fermi National Accelerator Laboratory (FNAL) Federally Funded Research and Development Center (FFRDC) Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S)	E. Jennings Taylor (Troy, Ohio); Maria E. Inman (Yellow Springs, Ohio); Timothy Hall (Englewood, Ohio)
ASSIGNEE(S)	FARADAY TECHNOLOGY, INC. (Englewood, Ohio)
INVENTOR(S)	E. Jennings Taylor (Troy, Ohio); Maria E. Inman (Yellow Springs, Ohio); Timothy Hall (Englewood, Ohio)
ABSTRACT	A method and system for electrochemically machining a hollow body of a metal or a metal alloy. An electrode is positioned within a hollow body including a metal or metal alloy, where the hollow body has a variable internal diameter. The hollow body is oriented vertically, with the electrode oriented vertically therein. The hollow body is at least partially filled with an aqueous, acidic electrolyte solution, the electrolyte solution being devoid of hydrofluoric acid and having a viscosity less than 15 cP. An electric current is passed between the hollow body and the electrode, where the electric current includes a plurality of anodic pulses and a plurality of cathodic pulses, and where the cathodic pulses are interposed between at least some of the anodic pulses.
FILED	Tuesday, December 30, 2014
APPL NO	14/585897
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal B23H 3/00 (20130101) Original (OR) Class Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/26 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/2406 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/20 (20130101)
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09988312 — Cation-enhanced chemical stability of ion-conducting zirconium-based ceramics

US 09988312	Spoerke et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Erik David Spoerke (Albuquerque, New Mexico); Paul G. Clem (Albuquerque, New Mexico); Jill S. Wheeler (Albuquerque, New Mexico); Leo J. Small (Albuquerque, New Mexico); Jon Ihlefeld (Charlottesville, Virginia)
ABSTRACT	At least partial substitution of zirconium by hafnium in ion-conducting zirconium-based ceramics provides enhanced chemical stability in alkaline and acid environments.
FILED	Thursday, March 16, 2017
APPL NO	15/460570
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/006 (20130101) C01G 27/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/50 (20130101) C01P 2004/80 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/16 (20130101) C04B 35/48 (20130101) C04B 35/447 (20130101) C04B 35/481 (20130101) Original (OR) Class C04B 41/00 (20130101) C04B 2235/447 (20130101) C04B 2235/3201 (20130101) C04B 2235/3203 (20130101) C04B 2235/3227 (20130101) C04B 2235/3244 (20130101)
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09988608 — Methods of expanding bacteriophage host-range and bacteriophage produced by the methods

US 09988608	Crown et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Kevin K. Crown (Albuquerque, New Mexico); Joshua Santarpia (Albuquerque, New Mexico)
ABSTRACT	A method of producing novel bacteriophages with expanded host-range and bacteriophages with expanded host ranges are disclosed. The method produces mutant phage strains which are infectious to a second host and can be more infectious to their natural host than in their natural state. The method includes repeatedly passaging a selected phage strain into bacterial cultures that contain varied ratios of its natural host bacterial strain with a bacterial strain that the phage of interest is unable to infect; the target-host. After each passage the resulting phage are purified and screened for activity against the target-host via double-overlay assays. When mutant phages that are shown to infect the target-host are discovered, they are further propagated in culture that contains only the target-host to produce a stock of the resulting mutant phage.
FILED	Wednesday, October 14, 2015
APPL NO	14/883366
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2795/00051 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101)
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09988677 — DNA/RNA sequencing using a semiconducting nanopore

US 09988677	Fleharty et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Mark Fleharty (Albuquerque, New Mexico); Dimiter N. Petsev (Albuquerque, New Mexico); Frank B. Van Swol (Tijeras, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Mark Fleharty (Albuquerque, New Mexico); Dimiter N. Petsev (Albuquerque, New Mexico); Frank B. Van Swol (Tijeras, New Mexico)
ABSTRACT	The present disclosure provides novel apparatus including, though not necessarily limited to, biosensors utilizing semiconductor materials in electrolyte solutions and methods for using the same. The biosensors rely on a unique property wherein a charged body in the electrolyte solution produces a detectable change in the local conductivity of the semiconductor as the body approaches or travels near the semiconductor.
FILED	Wednesday, June 10, 2015
APPL NO	14/735898
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3278 (20130101) G01N 33/48721 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/24 (20130101)
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09988746 — Partially degradable fibers and microvascular materials formed from the fibers

US 09988746	Dong et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL Basic Energy Sciences (BES) Energy Frontier Research Centers (EFRC)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Hefei Dong (Urbana, Illinois); Stephen J. Pety (Urbana, Illinois); Nancy R. Sottos (Champaign, Illinois); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois)
ABSTRACT	A partially degradable polymeric fiber includes a thermally degradable polymeric core and a coating surrounding at least a portion of the core. The thermally degradable polymeric core includes a polymeric matrix including a poly(hydroxyalkanoate), and a metal selected from the group consisting of an alkali earth metal and a transition metal, in the core polymeric matrix. The concentration of the metal in the polymeric matrix is at least 0.1 wt %. The partially degradable polymeric fiber may be used to form a microvascular system containing one or more microfluidic channels.
FILED	Friday, September 27, 2013
APPL NO	14/040287
ART UNIT	1789 — Miscellaneous Articles, Stock Material
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 15/00 (20130101) D03D 25/005 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2509/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/145 (20130101) H01M 2/162 (20130101) H01M 2/1653 (20130101) H01M 10/052 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/294 (20150115) Y10T 428/2933 (20150115) Y10T 442/30 (20150401)
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09989447 — Shape-preserving transformations of organic matter and compositions thereof

US 09989447	Kaehr et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico); STC.UNM (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Bryan J. Kaehr (Albuquerque, New Mexico); Kristin Meyer (Tijeras, New Mexico); Jason L. Townson (Seattle, Washington)
ABSTRACT	The present invention relates to methods of transforming organic matter into organic-inorganic composites, inorganic replicas, or conductive replicas. Organic matter, such as biological cells and tissue and organs, can be converted into such composites and replicas using the methods described herein. In particular, such methods transform organic matter (into inorganic, organic-inorganic, or conductive constructs), while simultaneously preserving microscopic and/or macroscopic structural detail.
FILED	Thursday, July 09, 2015
APPL NO	14/795366
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2806 (20130101) Original (OR) Class G01N 1/2853 (20130101)
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09989729 — Ultra stable resonant cavity for gas analysis systems

US 09989729	Koulikov
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	LI-COR, Inc. (Lincoln, Nebraska)
ASSIGNEE(S)	LI-COR, Inc. (Lincoln, Nebraska)
INVENTOR(S)	Serguei Koulikov (Los Altos, California)
ABSTRACT	Systems and methods for detecting trace gases utilize a resonance optical cavity and a coherent light source coupled to the cavity through a cavity coupling mirror. The cavity is constructed of a material having the same or a similar coefficient of thermal expansion as the mirror elements defining the cavity. The main (bulk) cavity material may be the same as the main (bulk) material that forms the mirror elements, or it may be different. Such resonant cavity configurations provide improved accuracy and stability as compared to existing cavity configurations based upon similar principles.
FILED	Tuesday, September 08, 2015
APPL NO	14/847977
ART UNIT	2877 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/031 (20130101) G01N 21/39 (20130101) G01N 21/3151 (20130101) Optical Elements, Systems, or Apparatus G02B 7/181 (20130101) Original (OR) Class G02B 17/004 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0071 (20130101)
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09990203 — Hardware accuracy counters for application precision and quality feedback

US 09990203	de Paula Rosa Piga et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S)	ADVANCED MICRO DEVICES, INC. (Sunnyvale, California)
INVENTOR(S)	Leonardo de Paula Rosa Piga (Austin, Texas); Abhinandan Majumdar (Ithaca, New York); Indrani Paul (Austin, Texas); Wei Huang (Austin, Texas); Manish Arora (Sunnyvale, California); Joseph L. Greathouse (Austin, Texas)
ABSTRACT	Methods, devices, and systems for capturing an accuracy of an instruction executing on a processor. An instruction may be executed on the processor, and the accuracy of the instruction may be captured using a hardware counter circuit. The accuracy of the instruction may be captured by analyzing bits of at least one value of the instruction to determine a minimum or maximum precision datatype for representing the field, and determining whether to adjust a value of the hardware counter circuit accordingly. The representation may be output to a debugger or logfile for use by a developer, or may be output to a runtime or virtual machine to automatically adjust instruction precision or gating of portions of the processor datapath.
FILED	Monday, December 28, 2015
APPL NO	14/981310
ART UNIT	2183 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 9/30083 (20130101) G06F 9/30145 (20130101) G06F 9/30192 (20130101) Original (OR) Class
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09990578 — Redox active polymer devices and methods of using and manufacturing the same

US 09990578	Johnson et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Paul Johnson (Phoenix, Arizona); Jose Antonio Bautista-Martinez (Mesa, Arizona); Cody Friesen (Fort McDowell, Arizona); Elise Switzer (Napa, California)
ABSTRACT	The disclosed technology relates generally to apparatus comprising conductive polymers and more particularly to tag and tag devices comprising a redox-active polymer film, and method of using and manufacturing the same. In one aspect, an apparatus includes a substrate and a conductive structure formed on the substrate which includes a layer of redox-active polymer film having mobile ions and electrons. The conductive structure further includes a first terminal and a second terminal configured to receive an electrical signal therebetween, where the layer of redox-active polymer is configured to conduct an electrical current generated by the mobile ions and the electrons in response to the electrical signal. The apparatus additionally includes a detection circuit operatively coupled to the conductive structure and configured to detect the electrical current flowing through the conductive structure.
FILED	Tuesday, May 12, 2015
APPL NO	14/710367
ART UNIT	2887 — Optics
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/122 (20130101) C08G 61/123 (20130101) C08G 2261/90 (20130101) C08G 2261/92 (20130101) C08G 2261/142 (20130101) C08G 2261/143 (20130101) C08G 2261/147 (20130101) C08G 2261/312 (20130101) C08G 2261/516 (20130101) C08G 2261/1452 (20130101) C08G 2261/3221 (20130101) C08G 2261/3223 (20130101) C08G 2261/3241 (20130101) C08G 2261/3243 (20130101) C08G 2261/3246 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0702 (20130101) G06K 19/0717 (20130101) G06K 19/0723 (20130101) G06K 19/07743 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/608 (20130101) H01M 2004/027 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49018 (20150115)
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09991376 — High voltage MOSFET devices and methods of making the devices

US 09991376	Banerjee et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Monolith Semiconductor Inc. (Round Rock, Texas)
ASSIGNEE(S)	Monolith Semiconductor Inc. (Round Rock, Texas)
INVENTOR(S)	Sujit Banerjee (Round Rock, Texas); Kevin Matocha (Round Rock, Texas); Kiran Chatty (Round Rock, Texas)
ABSTRACT	A SiC MOSFET device having low specific on resistance is described. The device has N+, P-well and JFET regions extended in one direction (Y-direction) and P+ and source contacts extended in an orthogonal direction (X-direction). The polysilicon gate of the device covers the JFET region and is terminated over the P-well region to minimize electric field at the polysilicon gate edge. In use, current flows vertically from the drain contact at the bottom of the structure into the JFET region and then laterally in the X direction through the accumulation region and through the MOSFET channels into the adjacent N+ region. The current flowing out of the channel then flows along the N+ region in the Y-direction and is collected by the source contacts and the final metal. Methods of making the device are also described.
FILED	Friday, December 11, 2015
APPL NO	14/966476
ART UNIT	2891 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/456 (20130101) H01L 29/0696 (20130101) H01L 29/0869 (20130101) H01L 29/0878 (20130101) H01L 29/1095 (20130101) H01L 29/1608 (20130101) H01L 29/4238 (20130101) H01L 29/7802 (20130101) Original (OR) Class H01L 29/7827 (20130101) H01L 29/42356 (20130101) H01L 29/66068 (20130101)
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09991443 — Conjugated polymer zwitterions and solar cells comprising conjugated polymer zwitterions

US 09991443	Emrick et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES)
APPLICANT(S)	The University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S)	Todd Emrick (Amherst, Massachusetts); Thomas Russell (Amherst, Massachusetts); Zachariah Page (Amherst, Massachusetts); Yao Liu (Amherst, Massachusetts)
ABSTRACT	A conjugated polymer zwitterion includes repeating units having structure (I), (II), or a combination thereof wherein Ar is independently at each occurrence a divalent substituted or unsubstituted C_3-30arylene or heteroarylene group; L is independently at each occurrence a divalent C_1-16alkylene group, C_6-30arylene or heteroarylene group, or alkylene oxide group; and R¹is independently at each occurrence a zwitterion. A polymer solar cell including the conjugated polymer zwitterion is also disclosed.
FILED	Monday, February 29, 2016
APPL NO	15/056395
ART UNIT	1758 — Miscellaneous Articles, Stock Material
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/00 (20130101) C08G 75/32 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0036 (20130101) Original (OR) Class H01L 51/0037 (20130101) H01L 51/0043 (20130101) H01L 51/0053 (20130101) H01L 51/4273 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101)
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09991512 — Thermally conductive lithium ion electrodes and batteries

US 09991512	Shevchenko et al.
FUNDED BY	Department of Defense (DOD) Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Elena Shevchenko (Riverside, Illinois); Anirudha V. Sumant (Plainfield, Illinois); Alexander Balandin (Riverside, California); Bonil Koo (Walnut Creek, California); Christopher Johnson (Naperville, Illinois); Tijana Rajh (Naperville, Illinois); Eungje Lee (Naperville, Illinois)
ABSTRACT	A thermally conductive electrochemical cell comprises a lithium ion-containing liquid electrolyte contacting a cathode and anode. The cathode and anode are in the form of electroactive sheets separated from each other by a membrane that is permeable to the electrolyte. One or more of the cathode and anode comprises two or more layers of carbon nanotubes, one of which layers includes electrochemically active nanoparticles and/or microparticles disposed therein or deposited on the nanotubes thereof. The majority of the carbon nanotubes in each of the layers are oriented generally parallel to the layers. Optionally, one or more of the layers includes an additional carbon material such as graphene, nanoparticulate diamond, microparticulate diamond, and a combination thereof.
FILED	Thursday, July 02, 2015
APPL NO	14/790449
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 10/052 (20130101)
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09991542 — Two-electron high potential and high capacity redox active molecules for energy storage applications

US 09991542	Huang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Jinhua Huang (Willowbrook, Illinois); Lu Zhang (Lisle, Illinois); Anthony K. Burrell (Naperville, Illinois)
ABSTRACT	A non-aqueous redox flow battery includes a catholyte including a compound of formula (I), a compound of formula (II), or a compound of formula (III): wherein two R groups have the formula X, wherein X is X, wherein X is a group of formula IV-A or IV-B;
FILED	Monday, August 31, 2015
APPL NO	14/840935
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) Original (OR) Class H01M 2300/0025 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101)
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09991545 — Metal-air flow batteries using oxygen enriched electrolyte

US 09991545	Zheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Communications-Electronics Research, Development and Engineering Center (CERDEC) Department of Energy (DOE)
APPLICANT(S)	FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
ASSIGNEE(S)	FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida)
INVENTOR(S)	Jian-ping Zheng (Tallahassee, Florida); Petru Andrei (Tallahassee, Florida); Annadanesh Shellikeri (Tallahassee, Florida); Xujie Chen (Tallahassee, Florida)
ABSTRACT	A metal air flow battery includes an electrochemical reaction unit and an oxygen exchange unit. The electrochemical reaction unit includes an anode electrode, a cathode electrode, and an ionic conductive membrane between the anode and the cathode, an anode electrolyte, and a cathode electrolyte. The oxygen exchange unit contacts the cathode electrolyte with oxygen separate from the electrochemical reaction unit. At least one pump is provided for pumping cathode electrolyte between the electrochemical reaction unit and the oxygen exchange unit. A method for producing an electrical current is also disclosed.
FILED	Wednesday, June 28, 2017
APPL NO	15/635777
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/96 (20130101) H01M 4/382 (20130101) H01M 8/20 (20130101) Original (OR) Class H01M 8/04276 (20130101) H01M 12/08 (20130101) H01M 2300/0002 (20130101) H01M 2300/0037 (20130101)
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09991559 — Functionalized ionic liquid electrolytes for lithium ion batteries

US 09991559	Zhang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Zhengcheng Zhang (Naperville, Illinois); Wei Weng (Woodridge, Illinois); Lu Zhang (Woodridge, Illinois); Khalil Amine (Oakbrook, Illinois)
ABSTRACT	An ionic liquid that is a salt has a Formula: Such ionic liquids may be used in electrolytes and in electrochemical cells.
FILED	Wednesday, June 17, 2015
APPL NO	14/742194
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Heterocyclic Compounds C07D 233/60 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) C07F 7/0854 (20130101) C07F 9/5407 (20130101) C07F 9/5414 (20130101) C07F 9/65515 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/399 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 12/02 (20130101) H01M 2300/0025 (20130101) H01M 2300/0045 (20130101) H01M 2300/0085 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101)
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09991707 — Aggregate Load Controllers and Associated Methods

US 09991707	Chassin
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	David P. Chassin (Pasco, Washington)
ABSTRACT	Aggregate load controllers and associated methods are described. According to one aspect, a method of operating an aggregate load controller includes using an aggregate load controller having an initial state, applying a stimulus to a plurality of thermostatic controllers which are configured to control a plurality of respective thermostatic loads which receive electrical energy from an electrical utility to operate in a plurality of different operational modes, accessing data regarding a response of the thermostatic loads as a result of the applied stimulus, using the data regarding the response, determining a value of at least one design parameter of the aggregate load controller, and using the determined value of the at least one design parameter, configuring the aggregate load controller to control amounts of the electrical energy which are utilized by the thermostatic loads.
FILED	Friday, July 24, 2015
APPL NO	14/809003
ART UNIT	2126 — AI & Simulation/Modeling
CURRENT CPC	Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/006 (20130101) F24F 11/30 (20180101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/005 (20130101) Original (OR) Class
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09992135 — Apparatus and method for fusion of compute and switching functions of exascale system into a single component by using configurable network-on-chip fabric with distributed dual mode input-output ports and programmable network interfaces

US 09992135	Khare et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	INTEL CORPORATION (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Surhud Khare (Bangalore, India); Dinesh Somasekhar (Portland, Oregon); Ankit More (Hillsboro, Oregon); David S. Dunning (Portland, Oregon); Nitin Y. Borkar (Portland, Oregon); Shekhar Y. Borkar (Beaverton, Oregon)
ABSTRACT	Described is an apparatus which comprises: a Network-On-Chip fabric using crossbar switches, having distributed ingress and egress ports; and a dual-mode network interface coupled to at least one crossbar switch, the dual-mode network interface is to include: a dual-mode circuitry; a controller operable to: configure the dual-mode circuitry to transmit and receive differential signals via the egress and ingress ports, respectively, and configure the dual-mode circuitry to transmit and receive signal-ended signals via the egress and ingress ports, respectively.
FILED	Friday, December 11, 2015
APPL NO	14/967166
ART UNIT	2474 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 45/72 (20130101) H04L 49/30 (20130101) Original (OR) Class H04L 49/101 (20130101)
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09992219 — Framework and methodology for supply chain lifecycle analytics

US 09992219	Hamlet et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	Jason Hamlet (Albuquerque, New Mexico); Brandon K. Eames (Albuquerque, New Mexico); Gio K. Kao (Albuquerque, New Mexico); Han Wei Lin (Albuquerque, New Mexico); Ryan Helinski (Albuquerque, New Mexico); John T. Michalski (Albuquerque, New Mexico)
ABSTRACT	The various technologies presented herein relate to pertaining to identifying and mitigating risks and attacks on a supply chain. A computer-implemented representation of a supply chain is generated comprising nodes (locations) and edges (objects, information). Risk to attack and different attack vectors can be defined for the various nodes and edges, and further, based upon the risks and attacks, (difficulty, consequence) pairs can be determined. One or more mitigations can be generated to increase a difficulty of attack and/or reduce consequence of an attack. The one or more mitigations can be constrained, e.g., by cost, time, etc., to facilitate determination of how feasible a respective mitigation is to implement with regard to finances available, duration to implement, etc. A context-free grammar can be utilized to identify one or more attacks in the supply chain. Further, the risks can undergo a ranking to enable mitigation priority to be determined.
FILED	Thursday, November 12, 2015
APPL NO	14/940005
ART UNIT	2491 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 17/3053 (20130101) G06F 17/30958 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06315 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) Original (OR) Class H04L 63/1441 (20130101)
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National Aeronautics and Space Administration (NASA)

09986934 — Microwave radar sensor modules

US 09986934	Lux et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	James Paul Lux (Thousand Oaks, California); Richard Kalantar Ohanian (Valley Village, California); Raymond Quintero (Santa Clarita, California); Troy Michael Torrez (Pasadena, California); Keizo Ishikawa (South Pasadena, California); Michael Ray McKee (Lancaster, California); Salman-ul Mohammed Haque (Los Angeles, California); Sarah Holmes (Glendale, California); Carl Spurgers (Rancho Cucamonga, California)
ABSTRACT	Systems and methods for detecting biometrics using microwave radar sensor modules are disclosed. Integrated microwave sensor modules can include a transmitter unit configured to generate at least one continuous wave transmit signal based upon at least one frequency control signal, a receiver unit configured to utilize a cancellation path to cancel contributions to a return signal based upon at least one cancellation path control signal, and a microcontroller unit that includes a processor, a memory containing a microcontroller application, where the microcontroller application configures the processor to generate at least one frequency control signal to generate least one CW transmit signal having a plurality of frequencies, generate at least one cancellation path control signal to automatically adjust the cancellation path in real time, receive at least one demodulated signal, digitize the at least one demodulated signal, and update the at least one frequency control and cancellation path control signals.
FILED	Thursday, January 29, 2015
APPL NO	14/609354
ART UNIT	3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/113 (20130101) A61B 5/0507 (20130101) Original (OR) Class A61B 2560/0252 (20130101)
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09987219 — UV-resistant microbes and UV-blocking microbial extract

US 09987219	Cuero et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Department of Agriculture (USDA)
APPLICANT(S)	The Texas A and M University System (College Station, Texas); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S)	Raul G. Cuero (Cypress, Texas); David S. McKay (Friendswood, Texas)
ABSTRACT	The present disclosure relates to a composition including an extract from an Acidithiobacillus bacteria or a yeast extracted after exposure of the bacteria to UV radiation. The disclosure further relates to a method of preparing a UV-blocking composition by exposing a culture of Acidithiobacillus or yeast to UV radiation and extracting UV-blocking cellular material produced in response to the UV radiation from the Acidithiobacillus or yeast. The disclosure further relates to a method of protecting an item from UV radiation damage by extracting UV-blocking cellular material from Acidithiobacillus or yeast exposed to UV radiation and covering the item with the UV-blocking cellular material. The disclosure further relates to a UV-resistant yeast cell and a UV-resistant bacterial cell.
FILED	Thursday, August 31, 2017
APPL NO	15/692066
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/02 (20130101) A01N 63/04 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/99 (20130101) Original (OR) Class Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101)
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09987658 — Method of manufacturing a humidity sensing material

US 09987658	Rolin et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Aministrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Terry D. Rolin (Elkmont, Alabama); Ian K. Small (Huntsville, Alabama)
ABSTRACT	A method is provided for manufacturing a humidity sensing material. Particles of a trivalent rare earth hydroxide or oxide (such as lanthanum hydroxide) are mixed with particles of barium oxide and titanium dioxide in specified proportions. The particle mixture is heated to generate a sintered mixture that is milled. The resulting milled particles are mixed with glass particles, an organic surfactant, a solvent, an organic vehicle, and an alkali hydroxide. The resulting liquid mixture is deposited as a layer thereof onto a substrate. The substrate and layer thereon are processed to remove liquid portions of the liquid mixture. Such liquid removal processing includes at least one cycle of heating the layer followed by a corresponding cycle of cooling the layer in a nitrogen atmosphere containing less than 25 parts per million of oxygen.
FILED	Wednesday, March 29, 2017
APPL NO	15/473322
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 3/048 (20130101) B05D 3/0254 (20130101) Original (OR) Class B05D 3/0413 (20130101) B05D 3/0493 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/4682 (20130101) C04B 35/6262 (20130101) C04B 35/6264 (20130101) C04B 35/6303 (20130101) C04B 35/62222 (20130101) C04B 2235/36 (20130101) C04B 2235/656 (20130101) C04B 2235/3215 (20130101) C04B 2235/3227 (20130101) C04B 2235/3236 (20130101) C04B 2235/5436 (20130101) C04B 2235/6581 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/223 (20130101) G01N 27/226 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09989680 — Controllable planar optical focusing system

US 09989680	Arbabi et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Amir Arbabi (Pasedena, California); Andrei Faraon (La Canada Flintridge, California)
ABSTRACT	An optical device has a first metasurface. A high-contrast pattern of the first metasurface is operable for modifying, over a first phase profile, a phase front of an incident light beam. A second metasurface, is disposed over a plane parallel to the first metasurface with a second high-contrast pattern and operable for shaping, over a second phase profile, the modified phase front of the incident light beam into a converging spherical phase front. A spacer layer, in which the modified phase front of the incident light beam diffracts, is disposed in a controllably changeable separation between the first and second metasurfaces. Controllably changing the separation between the first and the second metasurfaces by a first distance correspondingly changes the position of the focus point of the converging spherical phase front by a second distance.
FILED	Wednesday, October 26, 2016
APPL NO	15/335024
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 3/0087 (20130101) G02B 5/18 (20130101) G02B 5/1828 (20130101) Original (OR) Class G02B 5/1842 (20130101) G02B 5/1847 (20130101) G02B 7/08 (20130101) G02B 27/4277 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0018 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 3/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49844 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

09990335 — Universal and automated monte carlo method code for uncertainty propagation in metrology databases

US 09990335	Hayden et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Joseph Hayden (Ellicott City, Maryland); Manal A. Khreishi (Upper Marlboro, Maryland); Theodore A. Hadjimichael (Washington, District of Columbia); Raymond J. Ohl (Dayton, Maryland)
ABSTRACT	A method of providing transformed target points for integrating a component into an assembly includes collecting a set of component target points, collecting a set of assembly target points, identifying target points common to the set of component target points and the set of assembly target points; performing a specified number of Monte Carlo transformations of selected ones of the common target points to yield a set of transformed target points and vectors and an associated uncertainty value for each transformed target point and vector, and using certain ones of the transformed target points for integrating the component into the assembly based on the associated uncertainty value for each of the transformed target points.
FILED	Monday, June 27, 2016
APPL NO	15/193618
ART UNIT	2182 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 7/58 (20130101) G06F 17/18 (20130101) Original (OR) Class G06F 17/145 (20130101) G06F 2207/58 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09991677 — Index-coupled distributed-feedback semiconductor quantum cascade lasers fabricated without epitaxial regrowth

US 09991677	Briggs et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Ryan M. Briggs (Pasadena, California); Clifford F. Frez (Arcadia, California); Siamak Forouhar (Pasadena, California)
ABSTRACT	Quantum cascade (QC) lasers and methods of fabricating such QC lasers are provided. The QC lasers incorporate a DFB grating without requiring the use of relying on epitaxial regrowth processes. The DFB gratings are formed as sidewall gratings along the lateral length of the QC active region, or the DFB gratings are formed atop the lateral length of the QC active region, and wherein the top DFB grating is planarized with a polymeric material.
FILED	Wednesday, May 13, 2015
APPL NO	14/711695
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/12 (20130101) H01S 5/22 (20130101) H01S 5/125 (20130101) H01S 5/1237 (20130101) H01S 5/2216 (20130101) H01S 5/2275 (20130101) H01S 5/3402 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

09991958 — Satellite tracking with a portable telescope and star camera

US 09991958	Riesing et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	Kathleen Michelle Riesing (Cambridge, Massachusetts); Hyosang Yoon (Cambridge, Massachusetts); Kerri Lynn Cahoy (Lexington, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Kathleen Michelle Riesing (Cambridge, Massachusetts); Hyosang Yoon (Cambridge, Massachusetts); Kerri Lynn Cahoy (Lexington, Massachusetts)
ABSTRACT	A portable optical ground station can track a satellite with an amateur telescope mounted on a two-axis gimbal. The telescope is aligned with respect to an inertial, Earth-fixed frame using a wide field of view star camera. Star cameras are accurate to the arcsecond level and have the advantage of providing orientation with a single measurement. Using multiple star sensor measurements at different gimbal angles, it is possible to calculate the alignment of the gimbals in the Earth-fixed frame and the alignment of the star sensor in the gimbal frame. Once the alignment is obtained, satellite tracking can be achieved with a known orbit and precise Earth rotation model, such as the International Earth Rotation and Reference System Service (IERS). This alignment procedure can be carried out in less than one hour, making it practical to move and deploy the portable ground station.
FILED	Friday, June 16, 2017
APPL NO	15/625288
ART UNIT	2637 — Optical Communications
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/786 (20130101) Transmission H04B 10/118 (20130101) Original (OR) Class H04B 10/615 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Agriculture (USDA)

09987219 — UV-resistant microbes and UV-blocking microbial extract

US 09987219	Cuero et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) Department of Agriculture (USDA)
APPLICANT(S)	The Texas A and M University System (College Station, Texas); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S)	Raul G. Cuero (Cypress, Texas); David S. McKay (Friendswood, Texas)
ABSTRACT	The present disclosure relates to a composition including an extract from an Acidithiobacillus bacteria or a yeast extracted after exposure of the bacteria to UV radiation. The disclosure further relates to a method of preparing a UV-blocking composition by exposing a culture of Acidithiobacillus or yeast to UV radiation and extracting UV-blocking cellular material produced in response to the UV radiation from the Acidithiobacillus or yeast. The disclosure further relates to a method of protecting an item from UV radiation damage by extracting UV-blocking cellular material from Acidithiobacillus or yeast exposed to UV radiation and covering the item with the UV-blocking cellular material. The disclosure further relates to a UV-resistant yeast cell and a UV-resistant bacterial cell.
FILED	Thursday, August 31, 2017
APPL NO	15/692066
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/02 (20130101) A01N 63/04 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/99 (20130101) Original (OR) Class Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09988318 — Biodegradable fertilizer

US 09988318	Schrader et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	James Schrader (Boone, Iowa); William Graves, Jr. (Ames, Iowa); David Grewell (Ames, Iowa)
ABSTRACT	This invention relates to bio-renewable fertilizer compositions and methods of making and using the bio-renewable fertilizer compositions. In particular, the fertilizer compositions include biodegradable nutrient carriers, which have naturally derived, bio-renewable nitrogen content. The fertilizer compositions also contain biodegradable stabilizer.
FILED	Monday, October 12, 2015
APPL NO	14/880742
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Phosphatic Fertilisers C05B 17/00 (20130101) Original (OR) Class Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/00 (20130101) Mixtures of Fertilisers Covered Individually by Different Subclasses of Class C05; Mixtures of One or More Fertilisers With Materials Not Having a Specific Fertilising Activity, e.g Pesticides, Soil-conditioners, Wetting Agents; Fertilisers Characterised by Their Form C05G 3/00 (20130101) C05G 3/04 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

09988664 — Fiber sampler for recovery of bioaerosols and particles

US 09988664	Ensor et al.
FUNDED BY	Department of Homeland Security (DHS) Science and Technology Directorate (DHS-ST)
APPLICANT(S)	RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina)
ASSIGNEE(S)	Research Triangle Institute (Research Triangle Park, North Carolina)
INVENTOR(S)	David Samuel Ensor (Chapel Hill, North Carolina); Howard Jerome Walls (Apex, North Carolina); Karin K Foarde (Chapel Hill, North Carolina)
ABSTRACT	A bioparticle collection device and an aerosol collection system. The bioparticle collection device includes a collection medium including a plurality of fibers formed into a fiber mat and configured to collect bioparticles thereon, and includes a viability enhancing material provider disposed in a vicinity of the plurality of fibers and configured to provide a viability enhancing material to the collected bioparticles to maintain viability of the bioparticles collected by the fiber mat. The aerosol collection system includes an aerosol pumping device configured to entrain particles in an gas stream, an aerosol saturation device configured to saturate the particles in the gas stream with a biocompatible liquid, and an aerosol collection medium downstream from the aerosol saturation device and including a plurality of fibers formed into a fiber mat for collection of the saturated aerosol particles.
FILED	Tuesday, November 24, 2015
APPL NO	14/950813
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Separation B01D 2239/025 (20130101) B01D 2239/0604 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2214 (20130101) G01N 2001/2223 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09989669 — Intermodal container scanning

US 09989669	Slovik
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)	The United States of America, as Represented by the Secretary, Department of Homel (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S)	Gregory C. Slovik (Washington, District of Columbia)
ABSTRACT	The present disclosure relates to scanning intermodal containers and system and methods thereof. In particular, this disclosure relates to screening intermodal container without disconnecting it from a straddle carrier use to move them about a port or intermodal area. In embodiments, a system includes one or more scanners position on a side of a pair of track opposite a side used to support the straddle carrier. The respective tracks are spaced sufficiently apart so an intermodal container can be positioned (lowered) between the tracks to be passed by the scanners while it remains attached to the straddle carrier.
FILED	Friday, October 23, 2015
APPL NO	14/921402
ART UNIT	2884 — Optics
CURRENT CPC	Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0008 (20130101) G01V 5/0016 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

09987611 — Non-thermal plasma conversion of hydrocarbons

US 09987611	Strohm et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	H Quest Vanguard, Inc. (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	H Quest Vanguard, Inc. (Pittsburgh, Pennsylvania)
INVENTOR(S)	James J. Strohm (Allison Park, Pennsylvania); George L. Skoptsov (Pittsburgh, Pennsylvania); Evan T. Musselman (Pittsburgh, Pennsylvania); Kurt W. Zeller (Pittsburgh, Pennsylvania)
ABSTRACT	A non-thermal plasma is generated to selectively convert a precursor to a product. More specifically, plasma forming material and a precursor material are provided to a reaction zone of a vessel. The reaction zone is exposed to microwave radiation, including exposing the plasma forming material and the precursor material to the microwave radiation. The exposure of the plasma forming material to the microwave radiation selectively converts the plasma forming material to a non-thermal plasma including formation of one or more streamers. The precursor material is mixed with the plasma forming material and the precursor material is exposed to the non-thermal plasma including exposing the precursor material to the one or more streamers. The exposure of the precursor material to the streamers and the microwave radiation selectively converts the precursor material to a product.
FILED	Tuesday, August 08, 2017
APPL NO	15/671584
ART UNIT	1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/126 (20130101) Original (OR) Class B01J 2219/0875 (20130101) B01J 2219/0894 (20130101) B01J 2219/1206 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801)
VIEW PATENT	@ USPTO: Full Text PDF

09989412 — Low-noise spectroscopic imaging system

US 09989412	Rowlette et al.
FUNDED BY	National Science Foundation (NSF) Directorate of Technology, Innovation and Partnerships (TIP) Translational Impacts (TI) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Daylight Solutions, Inc. (San Diego, California)
ASSIGNEE(S)	DAYLIGHT SOLUTIONS, INC. (San Diego, California)
INVENTOR(S)	Jeremy Rowlette (Escondido, California); Edeline Fotheringham (San Diego, California); William Chapman (San Diego, California); Miles Weida (Poway, California); David Arnone (Mountain View, California)
ABSTRACT	A spectral imaging device (12) includes an image sensor (28), an illumination source (14), a refractive, optical element (24A), a mover assembly (24C) (29), and a control system (30). The image sensor (28) acquires data to construct a two-dimensional spectral image (13A) during a data acquisition time (346). The illumination source (14) generates an illumination beam (16) that illuminates the sample (10) to create a modified beam (16I) that follow a beam path (16B) from the sample (10) to the image sensor (28). The refractive, optical element (24A) is spaced apart a separation distance (42) from the sample (10) along the beam path (16B). During the data acquisition time (346), the control system (30) controls the illumination source (14) to generate the illumination beam (16), controls the mover assembly (29) (24C) to modulate the separation distance (42), and controls the image sensor (28) to capture the data.
FILED	Friday, March 25, 2016
APPL NO	15/081743
ART UNIT	2487 — Recording and Compression
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/08 (20130101) G01J 3/10 (20130101) G01J 3/32 (20130101) G01J 3/42 (20130101) G01J 3/0208 (20130101) Original (OR) Class G01J 3/0262 (20130101) G01J 3/0289 (20130101) G01J 3/2803 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) G01N 21/39 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/361 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

09989498 — Nonlinear ultrasonic testing for non-destructive measurement of longitudinal thermal stresses in solids

US 09989498	Lanza di Scalea et al.
FUNDED BY	Department of Transportation (USDOT) Federal Railroad Administration (FRA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents Of The University of California (Oakland, California)
INVENTOR(S)	Francesco Lanza di Scalea (San Diego, California); Claudio Nucera (San Diego, California)
ABSTRACT	Methods and apparatus, including computer program products, are provided for nonlinear ultrasonic testing. In one aspect there is provided a method, which may include generating at least one ultrasonic wave to enable the at least one ultrasonic wave to propagate through a solid; detecting the at least one ultrasonic wave propagating through the solid; and determining a stress of the solid based on at least one of an imaginary component of a wavenumber, a wave amplitude, a wave strength, a statistical moment in a time domain, or a statistical moment in a frequency domain of the at least one ultrasonic wave.
FILED	Wednesday, February 05, 2014
APPL NO	14/766219
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0025 (20130101) G01M 5/0041 (20130101) G01M 5/0066 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) Original (OR) Class G01N 29/11 (20130101) G01N 29/46 (20130101) G01N 2291/0423 (20130101) G01N 2291/0425 (20130101) G01N 2291/02491 (20130101) G01N 2291/2623 (20130101) G01N 2291/2634 (20130101) G01N 2291/02827 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

09987834 — Apparatus and method for removing pressure adhesive labels from backing and affixing to target substrate

US 09987834	Hussain et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)	United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	Khalid Hussain (Kansas City, Missouri); David C. Faulkner (Saltford Bristol, United Kingdom)
ABSTRACT	A system, apparatus, and method for removing pressure adhesive indicia, such as labels or stamps, from their backing and affixing the same to a target substrate is provided. The automated process affixes stamps, for example, to the target substrate with both speed and precision of placement. Desired stamps can be selectively removed from a backing, for example, can be placed on variable locations upon the target substrate, and can be affixed in the desired orientation with precise spacing between stamps. The precision of affixation afforded by this system is commensurate with philatelic standards and is suitable for all pressure adhesive indicia where rapid and precise placement is desired for aesthetic or other reasons.
FILED	Friday, March 18, 2016
APPL NO	15/075067
ART UNIT	1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 38/10 (20130101) Original (OR) Class B32B 2519/00 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 17/00508 (20130101) G07B 2017/0062 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1132 (20150115) Y10T 156/1705 (20150115) Y10T 156/1793 (20150115) Y10T 156/1944 (20150115)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

09992658 — Payment reconciliation in mixed-ownership low-power mesh networks

US 09992658	Berenberg
FUNDED BY
APPLICANT(S)	Cubic Corporation (San Diego, California)
ASSIGNEE(S)	CUBIC CORPORATION (San Diego, California)
INVENTOR(S)	Paul Berenberg (Los Altos, California)
ABSTRACT	Systems and methods that enable scalable, cost-effective payment reconciliation between owners of devices at least temporarily connected in or to a particular low-power, ad hoc mesh network.
FILED	Friday, December 16, 2016
APPL NO	15/382023
ART UNIT	2477 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 12/1435 (20130101) Wireless Communication Networks H04W 4/24 (20130101) Original (OR) Class H04W 64/00 (20130101) H04W 84/18 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

What You'll Find On This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 05, 2018.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180605.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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