FedInvent™ Patents
Patent Details for Tuesday, June 19, 2018
This page was updated on Monday, March 27, 2023 at 05:34 AM GMT
Department of Health and Human Services (HHS)
| US 09999603 | Robertson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Gavin P. Robertson (Hummelstown, Pennsylvania); Omer F. Kuzu (Harrisburg, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for treatment of proliferative disease. In specific aspects, the present invention relates to compositions including (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine (leelamine) and arachidonyl trifluoromethyl ketone (ATK) in combination; methods for treatment of cancer including administration of leelamine and ATK in a subject in need thereof; and particularly methods for treatment of skin cancer including administration of leelamine and ATK in a subject in need thereof. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 14/777023 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 31/121 (20130101) A61K 31/121 (20130101) A61K 31/135 (20130101) Original (OR) Class A61K 31/135 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999620 | McDonnell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Donald P. McDonnell (Chapel Hill, North Carolina); Daniel Frigo (Houston, Texas); Anthony R. Means (Boerne, Texas) |
| ABSTRACT | Provided herein are compounds, compositions, including pharmaceutical compositions, having anti-cancer activity. Also provided are methods for diagnosing, detecting, and treating cancer in a subject, as well as a method for evaluating cancer stage in a subject, wherein the methods include determining the amount of a Ca2+/calmodulin dependent kinase kinase (CaMKK) in a sample. Further provided are methods of screening and identifying a compound that inhibits CaMKK. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/185853 |
| ART UNIT | 1674 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/7088 (20130101) Peptides C07K 16/40 (20130101) C07K 16/3069 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 207/11017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/57434 (20130101) G01N 2333/912 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101) G01N 2500/20 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999664 | Wilson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Ian A. Wilson (La Jolla, California); Robyn L. Stanfield (San Diego, California); Robert Pejchal (Lyme, New Hampshire) |
| ABSTRACT | The invention relates to an immunogenic HIV-1 gp120 mini V3 loop, which is a truncated version of the full-length gp120 V3 loop useful for crystallization with antibodies that recognize carbohydrate moieties. The invention also relates to the structure of a broadly neutralizing antibody as a complex with a glycosylated gp120 outer domain, as determined by crystallographic techniques, and the confirmation that a glycosylated gp120 outer domain has a functional relevant conformation, as well as the determination of key residues on a glycosylated gp120 outer domain, and uses thereof and compounds and compositions therefrom. Furthermore, the invention also relates to other peptides and mimetic peptides, which bind to broadly neutralizing antibodies. |
| FILED | Friday, April 11, 2014 |
| APPL NO | 14/251070 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class Peptides C07K 14/005 (20130101) C07K 16/44 (20130101) C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/15034 (20130101) C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 33/56988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999665 | Jacobs, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine, Inc. (Bronx, New York) |
| INVENTOR(S) | William Jacobs, Jr. (Pelham, New York); Pablo A. Gonzalez Munoz (Santiago-Chile, Chile); Betsy Herold (Rowayton, Connecticut); Christopher Petro (Pleasanton, California) |
| ABSTRACT | Recombinant herpes simplex virus 2 (HSV-2) vaccine vectors, virions thereof, compositions and vaccines comprising such, and methods of use thereof are each provided. |
| FILED | Thursday, February 04, 2016 |
| APPL NO | 15/015322 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/525 (20130101) A61K 2039/572 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16621 (20130101) C12N 2710/16622 (20130101) C12N 2710/16634 (20130101) C12N 2710/16643 (20130101) C12N 2710/16662 (20130101) C12N 2710/16671 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999668 | Govindan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Serengulam V. Govindan (Summit, New Jersey); Zhengxing Qu (Warren, New Jersey); Hans J. Hansen (Picayune, Mississippi); David M. Goldenberg (Mendham, New Jersey) |
| ABSTRACT | This invention relates to monovalent and multivalent, monospecific binding proteins and to multivalent, multispecific binding proteins. One embodiment of these binding proteins has one or more binding sites where each binding site binds with a target antigen or an epitope on a target antigen. Another embodiment of these binding proteins has two or more binding sites where each binding site has affinity towards different epitopes on a target antigen or has affinity towards either a target antigen or a hapten. The present invention further relates to recombinant vectors useful for the expression of these functional binding proteins in a host. More specifically, the present invention relates to the tumor-associated antigen binding protein designated RS7, and other EGP-1 binding-proteins. The invention further relates to humanized, human and chimeric RS7 antigen binding proteins, and the use of such binding proteins in diagnosis and therapy. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 15/816635 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 51/1045 (20130101) A61K 51/1051 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/3015 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999671 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); David B. Thompson (Cambridge, Massachusetts); John Anthony Zuris (Cambridge, Massachusetts) |
| ABSTRACT | Compositions, methods, strategies, kits, and systems for the delivery of negatively charged proteins, protein complexes, and fusion proteins, using cationic polymers or lipids are provided. Delivery of proteins into cells can be effected in vivo, ex vivo, or in vitro. Proteins that can be delivered using the compositions, methods, strategies, kits, and systems provided herein include, without limitation, enzymes, transcription factors, genome editing proteins, Cas9 proteins, TALEs, TALENs, nucleases, binding proteins (e.g., ligands, receptors, antibodies, antibody fragments; nucleic acid binding proteins, etc.), structural proteins, and therapeutic proteins (e.g., tumor suppressor proteins, therapeutic enzymes, growth factors, growth factor receptors, transcription factors, proteases, etc.), as well as variants and fusions of such proteins. |
| FILED | Thursday, October 30, 2014 |
| APPL NO | 14/529010 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/45 (20130101) A61K 38/465 (20130101) A61K 38/1767 (20130101) A61K 47/12 (20130101) Original (OR) Class Peptides C07K 14/00 (20130101) C07K 14/195 (20130101) C07K 14/463 (20130101) C07K 14/4702 (20130101) C07K 14/43595 (20130101) C07K 2319/60 (20130101) C07K 2319/80 (20130101) C07K 2319/85 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 9/1241 (20130101) Enzymes C12Y 207/07 (20130101) C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999689 | Weissleder et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ralph Weissleder (Peabody, Massachusetts); Thomas Reiner (Weehawken, New Jersey); Edmund J. Keliher (Topsfield, Massachusetts) |
| ABSTRACT | The present disclosure provides compositions and methods based on peptide-detectable agent conjugates that are useful for imaging beta cell mass. |
| FILED | Monday, March 21, 2016 |
| APPL NO | 15/076466 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0056 (20130101) Original (OR) Class A61K 51/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999694 | Bradbury et al. |
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| FUNDED BY |
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| APPLICANT(S) | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York); CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Michelle S. Bradbury (New York, New York); Ulrich Wiesner (Ithaca, New York); Oula Penate Medina (Kiel, Germany); Andrew Burns (Niskayuna, New York); Jason S. Lewis (New York, New York); Steven M. Larson (New York, New York) |
| ABSTRACT | The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo. In order to target a specific cell type, the nanoparticle may further be conjugated to a ligand, which is capable of binding to a cellular component associated with the specific cell type, such as a tumor marker. In one embodiment, a therapeutic agent may be attached to the nanoparticle. To permit the nanoparticle to be detectable by not only optical fluorescence imaging, but also other imaging techniques, such as positron emission tomography (PET), single photon emission computed tomography (SPECT), computerized tomography (CT), bioluminescence imaging, and magnetic resonance imaging (MRI), radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle. |
| FILED | Monday, March 17, 2014 |
| APPL NO | 14/215879 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/0093 (20130101) A61K 51/1244 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/552 (20130101) G01N 33/574 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/54346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09999704 — Amphiphilic degradable polymers for immobilization and sustained delivery of biomolecules
| US 09999704 | Song et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Jie Song (Shrewsbury, Massachusetts); Jing Zhang (Worcester, Massachusetts) |
| ABSTRACT | The invention provides a novel approach to controlled delivery of biomolecules (e.g., lipids and proteins) by employing novel amphiphilic polymers that are effective delivery vehicles. These unique amphiphilic polymers may be employed as controlled delivery vehicles or tissue engineering scaffolds wherein the delivery of lipophilic or amphiphilic bioactive molecules can be achieved. An amphiphilic biodegradable polymer platform is disclosed herein for the stable encapsulation and sustained release of biomolecules, such as S1P. |
| FILED | Thursday, February 26, 2015 |
| APPL NO | 15/121734 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 31/06 (20130101) A61L 31/06 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 31/146 (20130101) A61L 31/148 (20130101) A61L 2300/22 (20130101) A61L 2300/414 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/664 (20130101) C08G 63/823 (20130101) C08G 2230/00 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999756 | Emami et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kiarash Emami (Abington, Pennsylvania); Stephen J. Kadlecek (Philadelphia, Pennsylvania); Rahim R. Rizi (Ambler, Pennsylvania); Masaru Ishii (Bel Air, Maryland); Hooman Hamedani (Philadelphia, Pennsylvania) |
| ABSTRACT | Systems and methods for delivering a gaseous contrast agent to the lungs of a subject. |
| FILED | Wednesday, October 29, 2014 |
| APPL NO | 14/527369 |
| ART UNIT | 3768 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0813 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/08 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/06 (20130101) A61M 16/12 (20130101) A61M 16/122 (20140204) A61M 16/202 (20140204) A61M 16/204 (20140204) A61M 16/208 (20130101) A61M 16/0488 (20130101) A61M 16/0833 (20140204) A61M 16/0875 (20130101) A61M 31/005 (20130101) Original (OR) Class A61M 2016/003 (20130101) A61M 2016/0039 (20130101) A61M 2202/02 (20130101) A61M 2202/0007 (20130101) A61M 2202/0007 (20130101) A61M 2202/0007 (20130101) A61M 2202/0208 (20130101) A61M 2202/0291 (20130101) A61M 2205/3303 (20130101) A61M 2230/42 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000432 | Negishi |
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| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Ei-ichi Negishi (West Lafayette, Indiana) |
| ABSTRACT | The invention relates to highly enantioselective processes for the synthesis of chiral 1-alkanols via Zr-catalyzed asymmetric carboalumination of alkenes. |
| FILED | Friday, January 09, 2015 |
| APPL NO | 15/111449 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 29/10 (20130101) C07C 29/10 (20130101) C07C 29/10 (20130101) C07C 29/10 (20130101) C07C 29/44 (20130101) C07C 29/44 (20130101) C07C 29/44 (20130101) C07C 29/50 (20130101) Original (OR) Class C07C 29/62 (20130101) C07C 29/62 (20130101) C07C 29/095 (20130101) C07C 29/095 (20130101) C07C 29/095 (20130101) C07C 31/12 (20130101) C07C 31/12 (20130101) C07C 31/36 (20130101) C07C 31/125 (20130101) C07C 31/125 (20130101) C07C 31/125 (20130101) C07C 31/1355 (20130101) C07C 33/18 (20130101) C07C 41/26 (20130101) C07C 41/26 (20130101) C07C 43/13 (20130101) C07C 51/295 (20130101) C07C 51/295 (20130101) C07C 53/128 (20130101) C07C 67/03 (20130101) C07C 67/03 (20130101) C07C 67/317 (20130101) C07C 67/317 (20130101) C07C 67/343 (20130101) C07C 67/343 (20130101) C07C 69/14 (20130101) C07C 69/14 (20130101) C07C 69/732 (20130101) C07C 69/734 (20130101) C07C 2101/14 (20130101) Heterocyclic Compounds C07D 319/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/06 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000452 | Manetsch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Roman Manetsch (Boston, Massachusetts); Dennis E. Kyle (Lithia, Florida); Raghupathi Neelarapu (Newark, Delaware); Jordany R. Maignan (Land O Lakes, Florida); Cynthia L. Lichorowic (Durham, North Carolina); Alexis N. LaCrue (Temple Terrace, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Roman Manetsch (Boston, Massachusetts); Dennis E. Kyle (Lithia, Florida); Raghupathi Neelarapu (Newark, Delaware); Jordany R. Maignan (Land O Lakes, Florida); Cynthia L. Lichorowic (Durham, North Carolina); Alexis N. LaCrue (Temple Terrace, Florida) |
| ABSTRACT | Provided herein are quinolone-based compounds that can be used for treatment and/or prevention of malaria and formulations thereof. Also provided herein are methods of treating and/or preventing malaria in a subject by administering a quinolone-based compound or formulation thereof provided herein. |
| FILED | Monday, January 23, 2017 |
| APPL NO | 15/412667 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 215/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000459 | Beaton et al. |
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| FUNDED BY |
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| APPLICANT(S) | EPIGEN BIOSCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | Epigen Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Graham Beaton (San Diego, California); Fabio C. Tucci (San Diego, California); Satheesh B. Ravula (San Diego, California); Chandravadan R. Shah (San Diego, California); Hiep Luu (San Marcos, California) |
| ABSTRACT | Heterocyclic compounds are described that are lysophosphatidic acid receptor ligands that are useful in the treatment of lysophosphatidic acid receptor-dependent diseases and conditions, including but not limited to diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and inflammatory bowel disease; ocular diseases such as diseases involving retinal degeneration; nerve diseases such as pruritus and pain. Non-limiting examples of those compounds include (RS)-3-Cyclopropyl-2-{4-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-benzyloxy}-propionic acid and (R)-1-(4′-{5-[1-(2-Chloro-phenyl)-ethoxycarbonylamino]-4-fluoro-pyrazol-1-yl}-2-fluoro-biphenyl-4-yl)-cyclopropanecarboxylic acid. |
| FILED | Monday, March 17, 2014 |
| APPL NO | 14/776954 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 231/38 (20130101) C07D 231/52 (20130101) C07D 233/88 (20130101) C07D 239/42 (20130101) C07D 261/14 (20130101) Original (OR) Class C07D 263/48 (20130101) C07D 401/04 (20130101) C07D 413/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000465 | Hoekstra et al. |
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| FUNDED BY |
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| APPLICANT(S) | Viamet Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina); U.S. Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | William J. Hoekstra (Durham, North Carolina); Christopher M. Yates (Raleigh, North Carolina); Mark Behnke (Poolesville, Maryland); Asaf Alimardanov (North Bethesda, Maryland); Scott A. David (Huntsburg, Ohio); Douglas Franklin Fry (Euclid, Ohio) |
| ABSTRACT | The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof. |
| FILED | Thursday, March 19, 2015 |
| APPL NO | 15/126412 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 57/00 (20130101) C07B 2200/07 (20130101) Heterocyclic Compounds C07D 213/57 (20130101) C07D 401/06 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1856 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000469 | Haystead et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Timothy A. J. Haystead (Chapel Hill, North Carolina); Khaldon Bodoor (Irbid, Jordan); Philip F. Hughes (Chapel Hill, North Carolina) |
| ABSTRACT | Inducible HSP70 is overexpressed in a wide spectrum of human tumors and its expression correlates with metastasis and poor outcomes to radiation and chemotherapy in patients. Identification of small molecule inhibitors of HSP70 pose a new therapy to cancer treatment. HS72, a benzimidazole piperidinyl carboxamide has been identified as an allosteric inhibitor for HSP70 and has demonstrated good tumor growth inhibition in vivo. |
| FILED | Wednesday, March 25, 2015 |
| APPL NO | 15/128825 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/497 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000474 | Woster et al. |
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| FUNDED BY |
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| APPLICANT(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| INVENTOR(S) | Patrick M. Woster (Charleston, South Carolina); Youxuan Li (Greenbelt, Maryland) |
| ABSTRACT | Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of cancer. Additionally, provided is a method for treating cancer, comprising the step of administering a therapeutically effective amount of a compound according to formula (I), or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier to a patient in need thereof. |
| FILED | Friday, November 06, 2015 |
| APPL NO | 15/526040 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 263/34 (20130101) C07D 413/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000486 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kineta Four, LLC (Seattle, Washington) |
| ASSIGNEE(S) | Kineta Viral Hemorrhagic Fever, LLC (Seattle, Washington) |
| INVENTOR(S) | Dongcheng Dai (Corvallis, Oregon); James R. Burgeson (Albany, Oregon); Sean M. Amberg (Corvallis, Oregon); Dennis E. Hruby (Albany, Oregon) |
| ABSTRACT | Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353351 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 209/08 (20130101) C07D 235/06 (20130101) C07D 235/08 (20130101) C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 405/10 (20130101) C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000498 | Gangjee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania); Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania); Larry H. Matherly (Novi, Michigan) |
| ABSTRACT | Fused cyclic pyrimidine compounds, including tautomers thereof, and pharmaceutically acceptable salts, prodrugs, solvates and hydrates thereof, are disclosed having the general Formula I: These compounds are useful in methods for treating cancer, selectively targeting cancerous cells via the proton coupled folate transporter, folate receptor alpha, and/or folate receptor beta pathways, inhibiting GARFTase in cancerous cells, and selectively targeting activated macrophages in a patient having an autoimmune disease, such as rheumatoid arthritis. |
| FILED | Thursday, November 03, 2016 |
| APPL NO | 15/342359 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000505 | Ghosh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Arun K. Ghosh (West Lafayette, Indiana) |
| ABSTRACT | Embodiments of the present invention provide, among other compounds, a family of spliceosome-inhibiting compounds that can be used as therapeutic anti-cancer agents. The compounds are synthesized in a process that includes the catalytic cross metathesis of a cyclic epoxy alcohol to an amide. |
| FILED | Wednesday, November 19, 2014 |
| APPL NO | 15/038027 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 31/336 (20130101) A61K 31/495 (20130101) A61K 31/535 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) Heterocyclic Compounds C07D 309/14 (20130101) C07D 407/12 (20130101) C07D 493/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000511 | Walensky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Loren D. Walensky (Newton Centre, Massachusetts); Michelle L. Stewart (Brookline, Massachusetts); Nicole Cohen (Newton, Massachusetts) |
| ABSTRACT | This invention relates to compounds which selectively bind to the survival protein MCL-1 with high affinity and selectivity, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for modulating MCL-1 activity and for treating hyperproliferative disorders, angiogenesis disorders, cell cycle regulation disorders, autophagy regulation disorders, inflammatory disorders, and/or infectious disorders and/or for enhancing cellular engraftment and/or wound repair, as a sole agent or in combination with other active ingredients. |
| FILED | Wednesday, May 06, 2015 |
| APPL NO | 14/705764 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 251/20 (20130101) C07C 251/84 (20130101) C07C 311/20 (20130101) C07C 335/16 (20130101) C07C 337/08 (20130101) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 239/60 (20130101) C07D 249/12 (20130101) C07D 277/34 (20130101) C07D 279/06 (20130101) C07D 307/54 (20130101) C07D 327/04 (20130101) C07D 401/12 (20130101) C07D 403/04 (20130101) C07D 403/06 (20130101) C07D 403/08 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/06 (20130101) C07D 409/12 (20130101) C07D 409/14 (20130101) C07D 413/06 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) C07D 417/14 (20130101) C07D 513/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000525 | McCall et al. |
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| FUNDED BY |
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| APPLICANT(S) | ReveraGen Biopharma, Inc (Rockville, Maryland) |
| ASSIGNEE(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| INVENTOR(S) | John M. McCall (Boca Grande, Florida); Eric Hoffman (Kensington, Maryland); Kanneboyina Nagaraju (Columbia, Maryland) |
| ABSTRACT | The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/939717 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) A61K 31/575 (20130101) A61K 45/06 (20130101) Steroids C07J 5/003 (20130101) C07J 5/0038 (20130101) C07J 5/0053 (20130101) C07J 5/0069 (20130101) C07J 5/0076 (20130101) C07J 7/008 (20130101) C07J 9/00 (20130101) C07J 9/005 (20130101) Original (OR) Class C07J 13/005 (20130101) C07J 21/00 (20130101) C07J 51/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000531 | Sebti et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Said M. Sebti (Tampa, Florida); Jianfeng Cai (Tampa, Florida) |
| ABSTRACT | STAT3 hyperphosphorylation, dimerization and DNA binding are required for its ability to contribute to malignant transformation. As such, STAT3 has been recognized as a promising target for cancer therapy. Although a number of inhibitors of STAT3-STAT3 dimerization have been reported, molecular ligands that prevent interactions between STAT3 and DNA are very rare. The γ-AApeptide-based one-bead-one-compound (OBOC) combinatorial library was used, and identified γ-AApeptides that can selectively inhibit STAT3/DNA interaction and suppress the expression levels of STAT3 target genes in intact cells. The results not only validate γ-AApeptides as novel inhibitors of STAT3 signaling pathway, but also demonstrate that in addition to the SH2 domain, the DNA binding domain of STAT3 is targetable for the development of new generation of anti-cancer therapeutics. This also validates the approach of OBOC combinatorial library for the identification of ligands targeting traditionally recognized “undruggable targets”. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332402 |
| ART UNIT | 1676 — Organic Chemistry |
| CURRENT CPC | Peptides C07K 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000543 | Schellenberger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Amunix Operating Inc. (Mountain View, California) |
| ASSIGNEE(S) | Amunix Operating Inc. (Mountain View, California) |
| INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Willem P. Stemmer (Los Gatos, California); Chia-wei Wang (Milpitas, California); Nathan Geething (Santa Clara, California); Jeffrey L. Cleland (San Carlos, California) |
| ABSTRACT | The present invention relates to compositions comprising glucose regulating peptides linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of glucose regulating peptide-related diseases, disorders, and conditions. |
| FILED | Wednesday, November 30, 2016 |
| APPL NO | 15/365792 |
| ART UNIT | 1676 — Organic Chemistry |
| CURRENT CPC | Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2200/328 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/605 (20130101) Original (OR) Class C07K 2319/31 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000556 | Bok et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPART OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); INSTITUTO NACIONAL DE TECNOLOGIA AGROPECUARIA (Ciudad Autonoma de Buenos Aires, Argentina) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia); INSTITUTO NACIONAL DE TECHNOLOGIA AGROPECUARIA (Buenos Aires, Argentina) |
| INVENTOR(S) | Karin Bok (Bethesda, Maryland); Lorena Laura Garaicoechea (Buenos Aires, Argentina); Viviana Parreno (Buenos Aires, Argentina); Andrea Pamela Aguilar (Buenos Aires, Argentina); Marina Bok (Buenos Aires, Argentina); Lisbeth Kim Green (Olney, Maryland); Stanislav Vladimirovich Sosnovtsev (North Potomac, Maryland) |
| ABSTRACT | Isolated VHH monoclonal antibodies are disclosed that specifically bind to a Norovirus polypeptide. In some embodiments, the Norovirus is a Genogroup I Norovirus or a Genogroup II Norovirus. In other embodiments, the Norovirus is Norwalk or MD2004 virus. In some embodiments, the monoclonal antibodies specifically bind VP1. Also disclosed are compositions including the disclosed antibodies, nucleic acids encoding these antibodies, expression vectors including the nucleic acids, and isolated host cells that express the nucleic acids. The antibodies and compositions disclosed herein can be used for detecting the presence of a Norovirus in a biological sample, or detecting a Norovirus infection. Also disclosed are methods of treating and/or preventing a NoV infection. |
| FILED | Friday, May 09, 2014 |
| APPL NO | 14/889774 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/16011 (20130101) C12N 2770/16034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000577 | Justice et al. |
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| FUNDED BY |
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| APPLICANT(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| ASSIGNEE(S) | Research Institute At Nationwide Children's Hospital (Columbus, Ohio) |
| INVENTOR(S) | Sheryl S. Justice (Westerville, Ohio); Kevin M. Mason (Blakclick, Ohio); Alistair Harrison (Westerville, Ohio) |
| ABSTRACT | A method of treating otitis media in a subject is described that includes administering to the subject a therapeutically effective amount of an Actin-Related Protein 2/3 Complex (Arp2/3) inhibitor. The role of Arp2/3 in otitis media was identified using comprehensive proteomic and metabolomic studies of otitis media using the chinchilla model. |
| FILED | Friday, September 11, 2015 |
| APPL NO | 15/510942 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/16 (20130101) A61K 38/17 (20130101) A61K 39/0208 (20130101) A61K 47/00 (20130101) A61K 47/42 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/4233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000581 | Thompson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | David H. Thompson (West Lafayette, Indiana); Aditya Kulkarni (West Lafayette, Indiana); Christopher Collins (West Lafayette, Indiana); Yawo Mondjinou (West Lafayette, Indiana) |
| ABSTRACT | Various embodiments of the present invention are directed to polyrotaxanes comprising a poloxamer core and at least one cyclodextrin and methods for treating Niemann-Pick type C (NPC) and imaging (e.g., MRI) using the polyrotaxanes various embodiments of the present invention. |
| FILED | Wednesday, May 07, 2014 |
| APPL NO | 14/889722 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/724 (20130101) A61K 31/765 (20130101) A61K 47/547 (20170801) A61K 47/48215 (20130101) A61K 47/48969 (20130101) A61K 51/065 (20130101) A61K 51/1268 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0015 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000608 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Jianjun Cheng (Urbana, Illinois); Hanze Ying (Urbana, Illinois) |
| ABSTRACT | The disclosure provides reversible polymers from polyurea by modifying the nitrogen atom with hindered substituents. The reversibility of hindered urea bond (HUB) can be controlled by changing the bulkiness of the substituents, and N-tert-butyl-N-ethylurea (TBEU), with its high binding constant and short lifetime, is applicable in the design of reversible polymer and self-healing materials at mild temperatures without external stimuli. HUB can be used in the design of smart materials with its adjustable reversibility, facile synthesis, and compatibility with many other polymer structures. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776104 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/757 (20130101) C08G 18/758 (20130101) C08G 18/833 (20130101) C08G 18/3206 (20130101) C08G 18/3228 (20130101) C08G 18/3246 (20130101) C08G 18/3278 (20130101) C08G 71/02 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/04 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 175/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000745 | Ledbetter et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jeffrey A. Ledbetter (Seattle, Washington); Martha Hayden-Ledbetter (Seattle, Washington); Keith Elkon (Seattle, Washington); Xizhang Sun (Seattle, Washington) |
| ABSTRACT | Hybrid nuclease molecules and methods for treating an immune-related disease or disorder in a mammal, and a pharmaceutical composition for treating an immune-related disease in a mammal. |
| FILED | Monday, January 19, 2015 |
| APPL NO | 14/599567 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 47/68 (20170801) A61K 47/6815 (20170801) Peptides C07K 16/44 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Enzymes C12Y 301/27005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000755 | Sadovsky et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yoel Sadovsky (Pittsburgh, Pennsylvania); Carolyn Coyne Candrilli (Jefferson Hills, Pennsylvania) |
| ABSTRACT | It is disclosed herein that cultured primary placental human trophoblast (PHT) cells are highly resistant to infection by a number of disparate viruses, and confer this resistance to non-placental recipient cells by exosome-mediated delivery of microRNAs (miRs). PHT cells express high levels of unique, primate-specific miRNAs, expressed from the chromosome 19 miRNA cluster (C19MC). It is further disclosed herein that C19MC miRNAs are packaged within PHT-derived exosomes and attenuate viral replication in recipient cells by inducing autophagy. Thus, provided herein are methods of inhibiting, treating or preventing microbial infections by administering one or more miRs of the C19MC. Also provided are methods of inducing autophagy in a cell by contacting the cell with one or more miRs of the C19MC. |
| FILED | Friday, January 27, 2017 |
| APPL NO | 15/417717 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1131 (20130101) Original (OR) Class C12N 15/1132 (20130101) C12N 15/1133 (20130101) C12N 2310/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000756 | Sliz et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Piotr Sliz (Canton, Massachusetts); Yunsun Nam (Dallas, Texas) |
| ABSTRACT | The invention provides compositions and methods for regulating microRNA (miRNA) biogenesis. The invention also relates to compositions and methods for treating or preventing cancer in a subject in need thereof. |
| FILED | Tuesday, January 31, 2017 |
| APPL NO | 15/420571 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000770 | Famili et al. |
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| FUNDED BY |
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| APPLICANT(S) | Intrexon CEU, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | INTREXON CEU, INC. (Blacksburg, Virginia) |
| INVENTOR(S) | Imandokht Famili (San Diego, California); Renata Usaite Black (San Diego, California); Christophe H. Schilling (San Diego, California) |
| ABSTRACT | The invention relates to newly identified selectable marker systems, cells for use in a selectable marker system, and methods for using the selectable marker systems. |
| FILED | Tuesday, December 08, 2015 |
| APPL NO | 14/963163 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) C12N 15/85 (20130101) Original (OR) Class Enzymes C12Y 114/16001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000781 | Benkovic et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J Benkovic (State College, Pennsylvania); Frank Salinas (Wheaton, Illinois) |
| ABSTRACT | A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is treated with a high fidelity polymerase to permit the replication and amplification of the target nucleic acid sequence. In preferred embodiments, the polymerase comprises a polymerase holoenzyme. In further preferred embodiments, the recombination factor is bacteriophage T4 UvsX protein or homologs from other species, and the polymerase holoenzyme comprises a polymerase enzyme, a clamp protein and a clamp loader protein, derived from viral, bacteriophage, prokaryotic, archaebacterial, or eukaryotic systems. |
| FILED | Tuesday, March 15, 2016 |
| APPL NO | 15/070401 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1027 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2521/507 (20130101) C12Q 2521/513 (20130101) C12Q 2527/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000793 | Dertinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Litron Laboratories, Ltd. (Rochester, New York) |
| ASSIGNEE(S) | LITRON LABORATORIES, LTD. (Rochester, New York) |
| INVENTOR(S) | Stephen D. Dertinger (Webster, New York); Sian E. Cairns (Clifton Park, New York); Svetlana L. Avlasevich (Webster, New York); Dorothea K. Torous (Rochester, New York) |
| ABSTRACT | The present invention relates a method for the enumeration of mammalian cell micronuclei, while distinguishing micronuclei from the chromatin of dead and dying cells. The method utilizes differential staining of chromatin from dead and dying cells, to distinguish the chromatin from micronuclei and nuclei that can be detected based upon fluorescent emission and light scatter following exposure to an excitatory light source. Counting of micronuclei events relative to the number of nuclei can be used to assess the DNA-damaging potential of a chemical agent, the DNA-damaging potential of a physical agent, the effects of an agent which can modify endogenously-induced DNA damage, and the effects of an agent which can modify exogenously-induced DNA damage. Kits for practicing the invention are also disclosed. |
| FILED | Friday, August 16, 2013 |
| APPL NO | 13/969185 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 15/1475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000796 | Samusik et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nikolay Samusik (Mountain View, California); Garry P. Nolan (Redwood City, California); Yury Goltsev (Stanford, California) |
| ABSTRACT | A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the oligonucleotide, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/832621 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6818 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000798 | Williams |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| INVENTOR(S) | John G. K. Williams (Lincolnville, Maine) |
| ABSTRACT | The present invention provides novel compositions, methods and apparatus for DNA sequencing that can be performed, e.g., in a two-electrode chamber. The present invention also provides a method for sequencing a nucleic acid comprising immobilizing a plurality of complexes comprising a target nucleic acid, a primer nucleic acid, and a polymerase onto a surface, contacting the surface with a plurality of charged particles comprising a nucleotide phosphate by applying an electric field, reversing the electric field to transport unbound charged particles away from the surface, and detecting the incorporation of a nucleotide phosphate into a single molecule of the primer nucleic acid. |
| FILED | Tuesday, October 07, 2014 |
| APPL NO | 14/509006 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/005 (20130101) B01J 2219/00497 (20130101) B01J 2219/00576 (20130101) B01J 2219/00648 (20130101) B01J 2219/00722 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) C12Q 1/6825 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2523/307 (20130101) C12Q 2525/113 (20130101) C12Q 2525/117 (20130101) C12Q 2563/107 (20130101) C12Q 2563/149 (20130101) C12Q 2565/518 (20130101) C12Q 2565/518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000800 | Chee |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Prognosys Biosciences, Inc. (La Jolla, California) |
| INVENTOR(S) | Mark S. Chee (Encinitas, California) |
| ABSTRACT | The present invention provides oligonucleotide constructs, sets of such oligonucleotide constructs, and methods of using such oligonucleotide constructs to provide validated sequences or sets of validated sequences corresponding to desired ROIs. Such validated ROIs and constructs containing these have a wide variety of uses, including in synthetic biology, quantitative nucleic acid analysis, polymorphism and/or mutation screening, and the like. |
| FILED | Friday, July 29, 2016 |
| APPL NO | 15/224253 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000801 | Ju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York City, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Dae Hyun Kim (New York, New York); Lanrong Bi (New York, New York); Qinglin Meng (Foster City, California); Xiaoxu Li (New York, New York) |
| ABSTRACT | This invention provides a process for sequencing single-stranded DNA employing modified nucleotides. |
| FILED | Thursday, November 17, 2016 |
| APPL NO | 15/354531 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000804 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioNano Genomics, Inc. (San Diego, California) |
| ASSIGNEE(S) | BioNano Genomics, Inc. (San Diego, California) |
| INVENTOR(S) | Han Cao (San Diego, California); Parikshit A. Deshpande (Princeton, New Jersey); Michael D. Austin (San Diego, California); Michael Boyce-Jacino (Titusville, New Jersey) |
| ABSTRACT | Methods of analyzing features such as the physical size of macromolecules or biomarkers along large genomic DNA molecules were disclosed as wen as the devices for carrying out such high throughput analysis in a massively parallel fashion. Methods of fabricating such devices are also disclosed. |
| FILED | Monday, March 07, 2016 |
| APPL NO | 15/062622 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502761 (20130101) B01L 2200/12 (20130101) B01L 2200/0663 (20130101) B01L 2200/0668 (20130101) B01L 2300/041 (20130101) B01L 2300/089 (20130101) B01L 2300/161 (20130101) B01L 2300/0627 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0887 (20130101) B01L 2300/0896 (20130101) B01L 2400/086 (20130101) B01L 2400/0406 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2563/107 (20130101) C12Q 2600/172 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/645 (20130101) G01N 21/6428 (20130101) G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000813 | Roth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark J. Roth (Chevy Chase, Maryland); Konrad Huppi (Herndon, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Mark J. Roth (Chevy Chase, Maryland); Konrad Huppi (Herndon, Virginia) |
| ABSTRACT | The invention relates to method and compositions for treating and diagnosing cancer, in particular β-catenin related cancers. In general, the methods include administering RNAi constructs. The invention further relates to methods of identifying CTNNB1 related cancer therapeutics. |
| FILED | Tuesday, January 03, 2012 |
| APPL NO | 13/342877 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000815 | Bell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC (Boston, Massachusetts) |
| INVENTOR(S) | Daphne Winifred Bell (Chevy Chase, Maryland); Daniel A. Haber (Chestnut Hill, Massachusetts); Pasi Antero Janne (Newton, Massachusetts); Bruce E. Johnson (Brookline, Massachusetts); Thomas J. Lynch (Newton, Massachusetts); Matthew Meyerson (Concord, Massachusetts); Juan Guillermo Paez (Dean Funes, Argentina); William R. Sellers (Chestnut Hill, Massachusetts); Jeffrey E. Settleman (Newton, Massachusetts); Raffaella Sordella (Bedford, Massachusetts) |
| ABSTRACT | Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug. |
| FILED | Wednesday, March 04, 2015 |
| APPL NO | 14/638779 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/574 (20130101) G01N 2333/485 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001470 | Mercola et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mark Mercola (Rancho Santa Fe, California); Fabio Cerignoli (San Diego, California); Jeffrey Price (Rancho Santa Fe, California) |
| ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
| INVENTOR(S) | Mark Mercola (Rancho Santa Fe, California); Fabio Cerignoli (San Diego, California); Jeffrey Price (Rancho Santa Fe, California) |
| ABSTRACT | The present invention provides a method, system and composition for screening drug candidates for cardiotoxicity and for novel drugs that effect cardiomyocyte contractility and function. The invention provides an efficient and reliable screening assay to detect the effect of new and potential drug candidates on cardiomyocyte calcium flux, membrane depolarization, and/or the propagation of action potentials. |
| FILED | Friday, December 03, 2010 |
| APPL NO | 12/960313 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5061 (20130101) Original (OR) Class G01N 2333/705 (20130101) G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001483 | Yarchoan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Celgene Corporation (Summit, New Jersey); The United States of America, as represented by the Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health (Washington, District of Columbia) |
| ASSIGNEE(S) | Celgene Corporation (Summit, New Jersey); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Robert Yarchoan (Bethesda, Maryland); Jerome B. Zeldis (Princeton, New Jersey); Mark N. Polizzotto (New South Wales, Australia); David A. Davis (Bethesda, Maryland); Irini Sereti (Washington, District of Columbia); Thomas S. Uldrick (Washington, District of Columbia); Denise Whitby (Frederick, Maryland); Vikram Khetani (Short Hills, New Jersey) |
| ABSTRACT | Provided herein are uses of gene and protein biomarkers as a predictor of clinical sensitivity of Kaposi's sarcoma (KS) or Kaposi's sarcoma-associated herpesvirus (KSHV) induced lymphoma and patient response to treatment with an immunomodulatory compound. Further provided herein are methods for the treatment or management of Kaposi's sarcoma or KSHV-induced lymphoma with an immunomodulatory compound, alone or in combination with doxorubicin. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/192819 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) A61K 31/704 (20130101) A61K 31/4035 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) Original (OR) Class G01N 2333/70539 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001484 | Egland et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sanford Health (Sioux Falls, South Dakota) |
| ASSIGNEE(S) | Sanford Health (Sioux Falls, South Dakota) |
| INVENTOR(S) | Kristi Egland (Sioux Falls, South Dakota); Rick Evans (Sioux Falls, South Dakota); James Pottala (Sioux Falls, South Dakota) |
| ABSTRACT | The present invention provides compositions including reagents for detecting human autoantibodies against at least two proteins selected from the group consisting of ANGTPL4, DKK1, EPHA2, LAMC2, SPON2, SSR2, GAL1, GFRA1, LRRC15, CD147, CD320, CDH3, LRP10, SPINT2, SUSD2, and CST2, and their use in detecting breast cancer or disease recurrence. |
| FILED | Tuesday, March 17, 2015 |
| APPL NO | 14/660423 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/57415 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001536 | Sun |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Phillip Zhe Sun (Waltham, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Phillip Zhe Sun (Waltham, Massachusetts) |
| ABSTRACT | Systems and methods for indicating pH in a subject using a magnetic resonance imaging (MRI) system are provided. The method includes selecting a contrast agent, generating a chemical exchange saturation transfer (CEST) pulse sequence, performing the pulse sequence with the saturating pulse at a first power level, and performing the pulse sequence again with the saturating pulse at a power level different from the first power level. The method also includes generating values indicating pH of the subject, and generating a report indicating the pH using those values. |
| FILED | Wednesday, May 06, 2015 |
| APPL NO | 14/705898 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/483 (20130101) G01R 33/4804 (20130101) Original (OR) Class G01R 33/4828 (20130101) G01R 33/5601 (20130101) G01R 33/5605 (20130101) G01R 33/5608 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001622 | Price et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jeffrey H. Price (San Diego, California); Derek N. Fuller (San Diego, California); Albert L. Kellner (San Diego, California); Behrad Azimi (La Jolla, California) |
| ASSIGNEE(S) | Sanford Burnham Medical Research Institute (La Jolla, California); Vala Sciences, Inc. (San Diego, California) |
| INVENTOR(S) | Jeffrey H. Price (San Diego, California); Derek N. Fuller (San Diego, California); Albert L. Kellner (San Diego, California); Behrad Azimi (La Jolla, California) |
| ABSTRACT | Multifunction autofocus for automated microscopy includes automatic coarse focusing of an automated microscope by reflective positioning, followed by automatic image-based autofocusing of the automated microscope performed in reference to a coarse focus position. In some aspects, the image-based autofocusing utilizes astigmatism in microscope optics for multi-planar image acquisition along a Z axis direction of a microscope. In some other aspects, the image-based autofocusing utilizes astigmatism in microscope optics in combination with chromatic aberration for multi-planar image acquisition along the Z axis direction. |
| FILED | Tuesday, October 25, 2011 |
| APPL NO | 13/317727 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/38 (20130101) Original (OR) Class G02B 13/08 (20130101) G02B 21/242 (20130101) G02B 21/365 (20130101) Pictorial Communication, e.g Television H04N 5/2258 (20130101) H04N 5/23212 (20130101) H04N 9/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002034 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Peter C. Li (McLean, Virginia); Manabu Torii (Newark, Delaware); David M. Hartley (Rockville, Maryland); Noele P. Nelson (Atlanta, Georgia) |
| ABSTRACT | A system and method involves detecting operational social disruptive events on a global scale, modeling data in conjunction with linguistics analysis to establish responsive actions, and generating visualization and executing models for communicating information. |
| FILED | Tuesday, March 18, 2014 |
| APPL NO | 14/218123 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class G06F 17/30867 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002228 | Mackerell, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Alexander D. Mackerell, Jr. (Baltimore, Maryland); Olgun Guvench (Portland, Maine) |
| ABSTRACT | The invention describes an explicit solvent all-atom molecular dynamics methodology (SILCS: Site Identification by Ligand Competitive Saturation) that uses small aliphatic and aromatic molecules plus water molecules to map the affinity pattern of a large molecule for hydrophobic groups, aromatic groups, hydrogen bond donors, and hydrogen bond acceptors. By simultaneously incorporating ligands representative of all these functionalities, the method is an in silico free energy-based competition assay that generates three-dimensional probability maps of fragment binding (FragMaps) indicating favorable fragment:large molecule interactions. The FragMaps may be used to qualitatively inform the design of small-molecule ligands or as scoring grids for high-throughput in silico docking that incorporates both an atomic-level description of solvation and the large molecule's flexibility. |
| FILED | Thursday, November 19, 2015 |
| APPL NO | 14/945792 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) G06F 19/12 (20130101) Original (OR) Class G06F 19/16 (20130101) G06F 19/706 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002230 | Courchesne et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eric Courchesne (San Diego, California); Tiziano Pramparo (San Diego, California) |
| ABSTRACT | The invention provides a method and system combining functional genomic and genetic, proteomic, anatomic neuroimaging, functional neuroimaging, behavioral and clinical measurements and data analyses for autism pediatric population screening, diagnosis or prognosis. More specifically, the invention provides a weighted gene and feature test for autism which uses a weighted gene signature matrix for comparison to a reference database of healthy and afflicted individuals. The invention also provides normalized gene expression value signatures for comparison to a reference database. The invention additionally combines either the weighted gene or the normalized gene analysis with comparisons to a gene-networks signature matrix, a multi-modal signature matrix, and a collateral features signature matrix for improved accuracy in screening, diagnostic and prognostic relevance for autism, particularly for newborns, babies ages birth to 1 year, toddlers ages 1 to 2 years, toddlers ages 2 to 3 years and young children ages 3 through 4 years. |
| FILED | Monday, January 26, 2015 |
| APPL NO | 14/604834 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/28 (20130101) Electric Digital Data Processing G06F 19/20 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002445 | Mistretta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Charles A. Mistretta (Madison, Wisconsin); Michael A. Speidel (Madison, Wisconsin); Jordan Slagowski (Madison, Wisconsin) |
| ABSTRACT | A system and method are provided for medical imaging that includes acquiring, during a common imaging acquisition process, rotational, x-ray volume image data and x-ray tomosynthesis image data from a subject. The method includes reconstructing a time-resolved three-dimensional (3D) image volume from the rotational, x-ray volume image data and producing a four-dimensional (4D) image series of the subject with resolved overlapping features by selectively combining the time-resolved 3D image volume and the x-ray tomosynthesis imaging data. |
| FILED | Friday, February 26, 2016 |
| APPL NO | 15/055272 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 11/003 (20130101) Original (OR) Class G06T 2207/10076 (20130101) G06T 2207/10112 (20130101) G06T 2207/30101 (20130101) G06T 2211/404 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002540 | Michalowski et al. |
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| FUNDED BY |
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| APPLICANT(S) | Adventium Enterprises, LLC (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Andamio Games LLC (Minneapolis, Minnesota) |
| INVENTOR(S) | Martin Michalowski (Minneapolis, Minnesota); Todd P. Carpenter (St. Paul, Minnesota); Kyle S. Nelson (Minneapolis, Minnesota) |
| ABSTRACT | Systems, devices, and methods associated with interactive educational tools are described herein. One device includes instructions executable by a processor to cause a plurality of mobile devices to each represent a respective subsystem associated with an objective, cause an interaction between at least two of the plurality of mobile devices to represent a relationship between the respective subsystems represented by the at least two mobile devices, and aggregate a number of interactions between the at least two of the plurality of mobile devices to form a coordinated response associated with achieving a particular objective. |
| FILED | Friday, June 05, 2015 |
| APPL NO | 14/731872 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/125 (20130101) G09B 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 09999591 | Guerry et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Patricia Guerry (Silver Spring, Maryland); Mario Artur Monteiro (Guelph, Canada) |
| ABSTRACT | The inventive subject matter relates to an immunogenic composition against Campylobacter jejuni comprising isolated capsule polysaccharide from selected pathogenic Campylobacter jejuni strains. The inventive subject matter also relates to methods of using the polysaccharide compositions in inducing and anti-C. jejuni immune response. |
| FILED | Monday, June 08, 2015 |
| APPL NO | 14/733114 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Original (OR) Class A61K 31/715 (20130101) A61K 39/105 (20130101) A61K 47/646 (20170801) A61K 47/6415 (20170801) A61K 2039/6037 (20130101) A61K 2039/55505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999599 | Thayumanavan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Sankaran Thayumanavan (Amherst, Massachusetts); Conghui Yuan (Amherst, Massachusetts) |
| ABSTRACT | The invention provides novel nanoscale delivery vehicles and composite nanoassemblies built from distinct nanoassembly units (e.g., block copolymer micelles and nanogels) with stoichiometric control. These intelligent composite nanoassemblies independently retain the key features of the nanoassembly units and greatly expand the potential functional features attainable based on the surface functionalization. The invention provides a novel approach to constructing nano-vehicles with controllable morphology based on combination of cooperative releasing mechanisms (e.g., redox sensitive nanogels and pH sensitive micelles). Two kinds of guests can be seperately and stably encapsulated in the composite nanocontainers, and then released sequentially under the stimulation of pH change and reduced glutathione. |
| FILED | Tuesday, September 10, 2013 |
| APPL NO | 14/421875 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Original (OR) Class A61K 9/1075 (20130101) A61K 9/5138 (20130101) A61K 45/06 (20130101) A61K 47/32 (20130101) A61K 47/6903 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999684 | Arvanian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Victor L. Arvanian (Huntington, New York); Joel M. Levine (Miller Place, New York) |
| ABSTRACT | The present disclosure is directed to adeno-associated viral vector monoclonal antibody constructs and compositions thereof, methods of improving locomotor function after spinal cord injury, methods of treating neurodegenerative diseases. |
| FILED | Friday, March 03, 2017 |
| APPL NO | 15/448946 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) A61K 38/51 (20130101) A61K 38/185 (20130101) A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14133 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 402/02004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999700 | Stewart |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Russell J. Stewart (Salt Lake City, Utah) |
| ABSTRACT | Described herein is the synthesis of adhesive from simple adhesive coacervates and their uses thereof. The adhesives are composed of (a) a polyanion in the absence of a polycation, wherein the polyanion comprises at least one crosslinking group capable of covalently crosslinking with itself, and (b) a sufficient amount of a complimentary multivalent cation or multivalent anion to produce the simple coacervate. The adhesives have numerous medical and non-medical applications. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/067291 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/0023 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/001 (20130101) A61L 24/06 (20130101) Original (OR) Class A61L 24/0015 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2300/418 (20130101) A61L 2400/18 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 143/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2852 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000384 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Xianfan Xu (West Lafayette, Indiana); Dapeng Wei (Chongqing, China PRC); Peide Ye (West Lafayette, Indiana) |
| ABSTRACT | A method of forming single and few layer graphene on a quartz substrate in one embodiment includes providing a quartz substrate, melting a portion of the quartz substrate, diffusing a form of carbon into the melted portion to form a carbon and quartz mixture, and precipitating at least one graphene layer out of the carbon and quartz mixture. |
| FILED | Thursday, May 30, 2013 |
| APPL NO | 13/906057 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000390 | Owens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Jeffery Ray Owens (Panama City, Florida); Derek Lovingood (Lynn Haven, Florida) |
| ABSTRACT | A method of synthesizing silica nanoparticles. The method includes hydrolyzing a silica precursor to form a plurality of monomers, each monomer of the plurality comprising a microwave reactive silicon species. The plurality of monomers is irradiated by an energy source configured to generate microwave frequency energy. Irradiation cases the plurality of monomers polymerize into a silica nanoparticle. |
| FILED | Thursday, May 29, 2014 |
| APPL NO | 14/290336 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/14 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 39/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/84 (20130101) C01P 2004/03 (20130101) C01P 2004/32 (20130101) C01P 2004/52 (20130101) C01P 2004/64 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/08 (20130101) D06M 11/79 (20130101) D06M 23/08 (20130101) D06M 2101/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2933 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000433 | Harvey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California) |
| ABSTRACT | The invention describes a high yield process that utilizes selective catalysts for the conversion of abundant, naturally occurring terpenes into bisphenols, and their derivative bis(cyanate)esters, resins, and polymers. High performance, low-cost composite materials with low moisture uptake and high glass transition temperatures suitable for aerospace applications can be prepared from these renewable starting materials. |
| FILED | Tuesday, September 27, 2016 |
| APPL NO | 15/277506 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 37/11 (20130101) C07C 37/60 (20130101) C07C 39/16 (20130101) Original (OR) Class C07C 261/02 (20130101) Heterocyclic Compounds C07D 303/30 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 64/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000451 | Jong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Ling Jong (Menlo Park, California); Chih-Tsung Chang (Menlo Park, California); Jaehyeon Park (Menlo Park, California) |
| ABSTRACT | The invention provides mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) inhibitors, and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant diminution of tumor cell growth, cancer or metastasis. |
| FILED | Saturday, July 15, 2017 |
| APPL NO | 15/650902 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Heterocyclic Compounds C07D 209/12 (20130101) C07D 209/14 (20130101) Original (OR) Class C07D 403/02 (20130101) C07D 405/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000483 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Steven Balk (Needham, Massachusetts); Qingsong Liu (Brookline, Massachusetts); Sen Chen (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the compounds of Formula (I) or (II), or compositions thereof, for treating or preventing a wide range of diseases (e.g., proliferative diseases (e.g., cancers, benign neoplasms, angiogenesis, inflammatory diseases, autoimmune diseases) and metabolic diseases (e.g., diabetes (e.g., type 2 diabetes, gestational diabetes)) in a subject. Treatment of a subject with a disease using a compound of Formula (I) or (II), or compositions thereof, may downregulate the expression and/or inhibit the activity of a kinase (e.g., a tyrosine kinase, such as a Tec kinase, in particular, bone marrow on X chromosome kinase (BMX)), and therefore, suppress tyrosine kinase singling in the subject. |
| FILED | Friday, October 18, 2013 |
| APPL NO | 14/436387 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000525 | McCall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ReveraGen Biopharma, Inc (Rockville, Maryland) |
| ASSIGNEE(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| INVENTOR(S) | John M. McCall (Boca Grande, Florida); Eric Hoffman (Kensington, Maryland); Kanneboyina Nagaraju (Columbia, Maryland) |
| ABSTRACT | The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/939717 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) A61K 31/575 (20130101) A61K 45/06 (20130101) Steroids C07J 5/003 (20130101) C07J 5/0038 (20130101) C07J 5/0053 (20130101) C07J 5/0069 (20130101) C07J 5/0076 (20130101) C07J 7/008 (20130101) C07J 9/00 (20130101) C07J 9/005 (20130101) Original (OR) Class C07J 13/005 (20130101) C07J 21/00 (20130101) C07J 51/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000603 | Sotzing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| ASSIGNEE(S) | THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Gregory Allen Sotzing (Storrs, Connecticut); Aaron Baldwin (Canterbury, Connecticut) |
| ABSTRACT | Disclosed are organotin ester polymers, methods of manufacture, and uses thereof. The organotin ester polymers exhibit both high dielectric constant and low conductivity suitable for use as dielectric insulating materials. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950924 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/81 (20130101) Original (OR) Class C08G 63/681 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000643 | Tsang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph W. Tsang (Ridgecrest, California); Michael E. Wright (Ridgecrest, California); Andrew P. Chafin (Ridgecrest, California) |
| ABSTRACT | The present invention provides a pigment/additive comprising discrete multivalent oxidation state (DiMVO) phenothiazine compounds having corrosion inhibiting properties. These novel DiMVO phenothiazines are useful in preparing waterborne primer coating formulations for application to metals and metal alloys and demonstrating corrosion inhibiting properties. Furthermore, such formulations are chromate-free and have reduced VOC content. Methods of preparing and using such compounds and waterborne formulations also are described. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 14/958526 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/34 (20130101) C08K 5/45 (20130101) C08K 5/46 (20130101) C08K 5/3432 (20130101) C08K 5/3437 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/002 (20130101) C09D 5/086 (20130101) Original (OR) Class C09D 163/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 15/26 (20130101) C09K 15/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000796 | Samusik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nikolay Samusik (Mountain View, California); Garry P. Nolan (Redwood City, California); Yury Goltsev (Stanford, California) |
| ABSTRACT | A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the oligonucleotide, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/832621 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6818 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001026 | Schwalm et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sunstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Gregory K. Schwalm (Avon, Connecticut); Gary M. McBrien (S. Glastonbury, Connecticut) |
| ABSTRACT | An in-line shutoff valve includes a valve body with an inlet chamber, an outlet chamber, and a poppet seat disposed between the inlet and outlet chambers. A poppet is movably disposed within the valve body and has an open and closed position. The poppet seats against the poppet seat in the closed position, fluidly separating the inlet chamber from the outlet chamber. The poppet is unseated from the poppet seat in the open position, fluidly coupling the inlet and outlet chambers. A manifold with a servo port and a vent port is disposed within the valve body between the inlet and outlet chambers, the vent port being in fluid communication with the servo port to cool valve internal structures when the poppet is in the closed position. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/159268 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/105 (20130101) F01D 17/145 (20130101) Original (OR) Class F01D 25/12 (20130101) Non-positive-displacement Pumps F04D 27/009 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/12 (20130101) F16K 1/126 (20130101) F16K 17/02 (20130101) F16K 31/04 (20130101) F16K 49/005 (20130101) F16K 49/007 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/3367 (20150401) Y10T 137/6579 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001149 | Galloway |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Kevin C. Galloway (Somerville, Massachusetts) |
| ABSTRACT | A soft composite actuator is described, including a first elastomeric layer; a strain limiting layer; and a first radially constraining layer, wherein the first elastomeric layer is disposed between the first radially constraining layer and the strain limiting layer; and the elastomeric layer, the strain limiting layer, and the radially constraining layer are bonded together to form at least one bladder for holding pressurized fluid. Methods of using and making of the soft composite actuator are described. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/502241 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) B25J 15/08 (20130101) B25J 15/10 (20130101) B25J 15/12 (20130101) B25J 15/0023 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/10 (20130101) Original (OR) Class F15B 15/103 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001239 | Blier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Darren J Blier (Westerly, Rhode Island); Louis E Sansone (Sterling, Connecticut); Michael A Vartanian (Lincoln, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Darren J Blier (Westerly, Rhode Island); Louis E Sansone (Sterling, Connecticut); Michael A Vartanian (Lincoln, Rhode Island) |
| ABSTRACT | A system to repair a hose made from deformable material includes an elongated container for holding a liquid heated sufficiently for softening the hose. A heater can be positioned in the container. A plurality of restraining members can be positioned to retain the hose immersed in the liquid within the container. A gas supply is used to pressurize the hose prior to immersion, and a support is provided for holding the hose before and after immersion. A method includes filling an elongated container with a heated liquid and pressurizing the hose with a gas. The pressurized hose is immersed in the liquid and maintained immersed by retaining members to soften the hose. The hose is removed from the liquid, depressurized and allowed to cool. |
| FILED | Thursday, January 05, 2017 |
| APPL NO | 15/398985 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 11/00 (20130101) F16L 55/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001278 | Roychoudhury et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Subir Roychoudhury (Madison, Connecticut); Richard Mastanduno (Milford, Connecticut); Bruce Crowder (Hamden, Connecticut); David Lang Spence (Beacon Falls, Connecticut); Francesco Macri (Farmington, Connecticut); Julian David Prada Bernal (New Haven, Connecticut) |
| ABSTRACT | An apparatus and method for operating a gas-fired burner on a liquid fuel. The apparatus integrates a catalytic liquid fuel reformer with a flame burner designed for operation on a gaseous fuel of high Wobbe Index, e.g., natural gas. The method involves reacting a mixture of a liquid fuel and oxidant in a catalytic reformer to obtain a gaseous reformate having a low Wobbe Index; and thereafter combusting the gaseous reformate, optionally augmented with liquid co-fuel and oxidant, in the gas-fired burner under diffusion flame conditions. The invention allows commercial gas-fired appliances, such as stoves, ovens, ranges, grills, griddles, stock pot burners, clothes dryers, hot water heaters, and boilers to be operated on a liquid fuel, which offers advantages in logistics and camp operations. |
| FILED | Monday, December 28, 2015 |
| APPL NO | 14/998388 |
| ART UNIT | 3743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Feeding Fuel to Combustion Apparatus F23K 5/002 (20130101) F23K 5/10 (20130101) Original (OR) Class Regulating or Controlling Combustion F23N 1/00 (20130101) F23N 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001417 | Ubelhor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ryan Ubelhor (Solsberry, Indiana); Daniel Ellison (Odon, Indiana); Cecilia Pierce (Bedford, Indiana) |
| ABSTRACT | Apparatus and methods are provided for providing flexible and repairable testing capabilities for systems that generate or absorb heat such as energy storage systems. One embodiment can include a temperature bath structure adapted to contain and maintain a fluid bath at a predetermined temperature, an outer containment structure adapted to insert into the temperature bath structure, heat sinks, thermal sensor assemblies, and an internal containment structure where the thermal sensor assemblies and heat sinks removably attach to different sections of the inner containment structure so as to measure heat flow into or out of the inner containment structure's different sections. Embodiments of the invention enable rapid insertion/removal of samples as well as replacement of sections of the system including embodiments or parts of thermal sensor assemblies as well as enabling separate thermal measurements associated with different sections of a sample under test within the inner containment structure. |
| FILED | Tuesday, April 18, 2017 |
| APPL NO | 15/490281 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) G01K 19/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001442 | Xie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ya-Hong Xie (Dana Point, California); Pu Wang (Los Angeles, California) |
| ABSTRACT | An optical probe includes an optical fiber with a first end and a second end, and an enhanced surface on a portion of the first end of the optical fiber. The enhanced surface includes a patterned base layer including multiple protruding nano-pyramids, an intermediate layer over the patterned base layer, and a graphene layer over the intermediate layer. Using a layer of graphene to cover the enhanced surface increases the sensitivity of a surface-enhanced Raman spectroscopy (SERS) process performed in conjunction with the enhanced surface, and further increases the chemical stability and bio-compatibility of the enhanced surface. Further, placing the enhanced surface at the end of the optical fiber provides a self-contained probe for use with a SERS process, thereby allowing for in-vivo characterization of a sample. |
| FILED | Friday, June 13, 2014 |
| APPL NO | 14/304290 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class G01N 2021/656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001457 | Goldfine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Neil J. Goldfine (Newton, Massachusetts); Yanko K. Sheiretov (Waltham, Massachusetts); Floyd W. Spencer (Albuquerque, New Mexico); David A. Jablonski (Whitman, Massachusetts); David C. Grundy (Chelmsford, Massachusetts); Darrell E. Schlicker (Freeland, Michigan) |
| ASSIGNEE(S) | JENTEK SENSORS, INC. (Waltham, Massachusetts) |
| INVENTOR(S) | Neil J. Goldfine (Newton, Massachusetts); Yanko K. Sheiretov (Waltham, Massachusetts); Floyd W. Spencer (Albuquerque, New Mexico); David A. Jablonski (Whitman, Massachusetts); David C. Grundy (Chelmsford, Massachusetts); Darrell E. Schlicker (Freeland, Michigan) |
| ABSTRACT | Methods and apparatus for enhancing performance curve generation, damage monitoring, and improving non-destructive testing performance. Damage standards used for performance curve generation are monitored using a non-destructive testing (NDT) sensor during a damage evolution test performed with the standard. The evolution test may be intermittently paused to permit ground truth data to be collected in addition to the NDT sensor data. A damage evolution model may be used to estimate ground truth data during the intervening periods of the damage evolution test. The NDT sensor data and ground truth data are used to generate performance curves for the NDT system. Multiple sensors may be monitored at multiple locations on the damage standard and multiple damage evolution tests may be performed with multiple damage standards. |
| FILED | Thursday, April 19, 2012 |
| APPL NO | 13/451128 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0033 (20130101) G01M 5/0091 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/90 (20130101) Original (OR) Class G01N 29/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001542 | Steinbrecher |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donald H Steinbrecher (Brookline, Massachusetts) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Donald H Steinbrecher (Brookline, Massachusetts) |
| ABSTRACT | A method is provided for use of a segmented aperture communications system to determine a direction of arrival of a radio signal in which the system includes a receiver plane having equally spaced and planar aligned radio frequency ports. Computation of the aperture segments depends on the port coordinates where the geometric relationship of the segments is used to determine a time delay and direction of arrival of the signal. The ports receive at least two orthogonal polarizations that characterize the incoming signals. A central port is used as reference to determine a phase difference associated at each port. Two angles are calculated by a simultaneous solution of two phase difference measurements to determine the direction of arrival solution. A mean direction of arrival solution is obtained by averaging solution estimates that are obtained by repeating the direction of arrival determination using random port pairs. |
| FILED | Tuesday, August 29, 2017 |
| APPL NO | 15/688932 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/32 (20130101) Original (OR) Class G01S 3/74 (20130101) Antennas, i.e Radio Aerials H01Q 3/2682 (20130101) H01Q 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001579 | Barrowes |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Benjamin E Barrowes (Lyme, New Hampshire) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin E Barrowes (Lyme, New Hampshire) |
| ABSTRACT | A high-frequency electromagnetic induction system includes a frequency generator coupled to a transmitter coil, a receiver coil coupled to a processor and a high frequency and polarizability data profile for an object of interest. The high frequency and polarizability data profile includes a data object having an array of frequency values and magnetic polarizability values, which are obtained from the object of interest and processed by the processor. Also described is a method for populating the high frequency and polarizability data profile. |
| FILED | Wednesday, March 18, 2015 |
| APPL NO | 14/661779 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/165 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001616 | Abouraddy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida); HARRIS CORPORATION (Melbourne, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida); HARRIS CORPORATION (Melbourne, Florida) |
| INVENTOR(S) | Ayman F. Abouraddy (Oviedo, Florida); Felix A. Tan (Orlando, Florida); Donna M. Kocak (Indialantic, Florida) |
| ABSTRACT | An underwater fiber optic cable includes an optical fiber, and a jacket surrounding the optical fiber. The jacket includes a polymer having a first density, and particles distributed throughout the polymer having a second density greater than the first density. The particles have a predetermined volume fraction to thereby provide the underwater cable with a predetermined buoyancy when underwater. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 15/487575 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4427 (20130101) Original (OR) Class G02B 6/4432 (20130101) G02B 6/4486 (20130101) G02B 6/4494 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001620 | Olsen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Randall B. Olsen (Carlsbad, California) |
| ABSTRACT | A torque tube coupler that rigidly connects reflectors and provides for substantially 360° rotational freedom for the reflectors as well as the ability to transmit rotation from one reflector to another so that the reflectors may essentially be placed at the same angle. The torque coupler includes first and second torque tube coupler assemblies each configured to be connected to a reflector in a solar energy collection system. The torque coupler also includes a support point that supports said first torque coupler assembly and said second torque tube coupler assembly. This support point includes a shaft that facilitates the rigid connection of the first torque tube coupler assembly to the second torque tube coupler assembly and a bearing that facilitates 360° rotation of the first reflector and the second reflector. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/379756 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Couplings for Transmitting Rotation; Clutches; Brakes F16D 1/12 (20130101) F16D 1/0829 (20130101) Optical Elements, Systems, or Apparatus G02B 7/1821 (20130101) Original (OR) Class G02B 19/0019 (20130101) G02B 19/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002034 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Peter C. Li (McLean, Virginia); Manabu Torii (Newark, Delaware); David M. Hartley (Rockville, Maryland); Noele P. Nelson (Atlanta, Georgia) |
| ABSTRACT | A system and method involves detecting operational social disruptive events on a global scale, modeling data in conjunction with linguistics analysis to establish responsive actions, and generating visualization and executing models for communicating information. |
| FILED | Tuesday, March 18, 2014 |
| APPL NO | 14/218123 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class G06F 17/30867 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002104 | Gauthier, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Leo R. Gauthier, Jr. (Ellicott City, Maryland); Harlan Ray, III (Davidsonville, Maryland) |
| ABSTRACT | A serial digital data acquisition receiver (SDDAR) or system of receivers may include an opto-isolator assembly, sampling logic and a USB interface. Both a CLK signal and a DATA signal may each pass through the opto-isolator assembly upon receipt of the CLK and DATA signals at the SDDAR or system. The sampling logic may be operably coupled to the opto-isolator assembly and be configured to determine a point at which to sample the DATA signal based on state changes in the CLK signal. The USB interface may be operably coupled to the sampling logic and an output terminal. The USB interface may be configured to provide telemetry data for processing, display or recording at the output terminal, and may be configured to enable the SDDAR or system to be powered from the output terminal. |
| FILED | Thursday, June 02, 2016 |
| APPL NO | 15/170987 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 13/4068 (20130101) G06F 13/4282 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002119 | Reynolds et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| INVENTOR(S) | Taryn Reynolds (Hawthorne, California); Matthew R. Ward (Mercer Island, Washington) |
| ABSTRACT | A system and method for combining data from multiple reports into a single spreadsheet. The system and method include downloading at least two reports to a computing device and opening the at least two reports using the computing device. The system and method further include creating unique identifiers for each report and merging the at least two reports by mapping and combining relevant data into the single spreadsheet such that each line item in the spreadsheet includes the relevant data from the at least two reports. |
| FILED | Tuesday, January 06, 2015 |
| APPL NO | 14/590726 |
| ART UNIT | 2177 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 17/24 (20130101) G06F 17/246 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002249 | Stolfo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Salvatore J Stolfo (Ridgewood, New Jersey); Ke Wang (Sunnyvale, California); Janak Parekh (Manhasset, New York) |
| ABSTRACT | Systems, methods, and media for outputting data based on anomaly detection are provided. In some embodiments, a method for outputting data based on anomaly detection is provided, the method comprising: receiving, using a hardware processor, an input dataset; identifying grams in the input dataset that substantially include distinct byte values; creating an input subset by removing the identified grams from the input dataset; determining whether the input dataset is likely to be anomalous based on the identified grams, and determining whether the input dataset is likely to be anomalous by applying the input subset to a binary anomaly detection model to check for an n-gram in the input subset; and outputting the input dataset based on the likelihood that the input dataset is anomalous. |
| FILED | Friday, February 27, 2015 |
| APPL NO | 14/634101 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/56 (20130101) Original (OR) Class G06F 21/564 (20130101) G06F 2221/034 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002460 | Black et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Michael J. Black (Providence, Rhode Island); Alexandru O. Balan (Pawtucket, Rhode Island); Alexander W. Weiss (Shirley, Massachusetts); Leonid Sigal (Pittsburgh, Pennsylvania); Matthew M. Loper (Providence, Rhode Island); Timothy S. St. Clair (Cambridge, Massachusetts) |
| ABSTRACT | A system and method of estimating the body shape of an individual from input data such as images or range maps. The body may appear in one or more poses captured at different times and a consistent body shape is computed for all poses. The body may appear in minimal tight-fitting clothing or in normal clothing wherein the described method produces an estimate of the body shape under the clothing. Clothed or bare regions of the body are detected via image classification and the fitting method is adapted to treat each region differently. Body shapes are represented parametrically and are matched to other bodies based on shape similarity and other features. Standard measurements are extracted using parametric or non-parametric functions of body shape. The system components support many applications in body scanning, advertising, social networking, collaborative filtering and Internet clothing shopping. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 14/885333 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) G06K 9/6221 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0601 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 7/77 (20170101) G06T 17/00 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002958 | Kub et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Francis J. Kub (Arnold, Maryland); Travis J. Anderson (Alexandria, Virginia); Virginia D. Wheeler (Alexandria, Virginia); Andrew D. Koehler (Alexandria, Virginia); Karl D. Hobart (Alexandria, Virginia) |
| ABSTRACT | Systems and method are provided for depositing metal on GaN transistors after gate formation using a metal nitride Schottky gate. Embodiments of the present disclosure use a “diamond last” process using thermally stable metal nitride gate electrodes to enable thicker heat spreading films and facilitate process integration. In an embodiment, the “diamond last” process with high thermal conductivity diamond is enabled by the integration of thermally stable metal-nitride gate electrodes. |
| FILED | Thursday, June 08, 2017 |
| APPL NO | 15/617982 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0217 (20130101) H01L 21/0254 (20130101) H01L 21/283 (20130101) H01L 21/02057 (20130101) H01L 21/02115 (20130101) H01L 21/02378 (20130101) H01L 21/31111 (20130101) H01L 23/3732 (20130101) H01L 29/205 (20130101) H01L 29/402 (20130101) H01L 29/475 (20130101) H01L 29/0891 (20130101) H01L 29/2003 (20130101) H01L 29/7787 (20130101) Original (OR) Class H01L 29/42316 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002979 | Yao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey) |
| INVENTOR(S) | Jie Yao (Plainsboro, New Jersey) |
| ABSTRACT | Disclosed are a semiconductor photodiode (PD) or phototransistor (PT) photo detector with a unipolarly doped edge region containing a portion of the photon absorption layer and occupying over 99% of the photo detector area as projected on a plane parallel to the semiconductor substrate. Embodiments also relate to methods of making the photo detector. |
| FILED | Tuesday, May 30, 2017 |
| APPL NO | 15/608685 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1446 (20130101) H01L 27/14649 (20130101) H01L 27/14681 (20130101) H01L 31/105 (20130101) H01L 31/1075 (20130101) H01L 31/1105 (20130101) H01L 31/1844 (20130101) H01L 31/03042 (20130101) H01L 31/03046 (20130101) H01L 31/03529 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003291 | Sudhoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Scott Sudhoff (West Lafayette, Indiana); Steve Pekarek (West Lafayette, Indiana); Omar Abdul Laldin (Inglewood, California) |
| ABSTRACT | A hybrid electrical machine containing surface mounted magnets which includes a magnetically permeable cylindrically shaped stator assembly having at least one stator winding formed about a plurality of stator teeth, a rotor assembly concentrically disposed within the stator assembly, including a magnetically permeable rotor backiron, a rotational drive mechanism coupled to the rotor backiron, and a plurality of protruding rotor poles, each including a magnetically permeable pole support assembly, a winding provided around the pole support assembly, and a radially magnetized permanent magnet assembly disposed about the pole support assembly. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/693923 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 16/02 (20130101) H02K 21/042 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/14 (20130101) H02P 23/009 (20130101) Original (OR) Class H02P 25/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003402 | Boroson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Don M. Boroson (Needham, Massachusetts); Bryan S. Robinson (Arlington, Massachusetts); Daniel V. Murphy (Concord, Massachusetts); Jason Stewart (Stow, Massachusetts); Farzana I. Khatri (Lexington, Massachusetts); Steven Constantine (Westford, Massachusetts); David Jason Geisler (Watertown, Massachusetts); Timothy M. Yarnall (Amherst, New Hampshire); Zachary Darling (Somerville, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Don M. Boroson (Needham, Massachusetts); Bryan S. Robinson (Arlington, Massachusetts); Daniel V. Murphy (Concord, Massachusetts); Jason Stewart (Stow, Massachusetts); Farzana I. Khatri (Lexington, Massachusetts); Steven Constantine (Westford, Massachusetts); David Jason Geisler (Watertown, Massachusetts); Timothy M. Yarnall (Amherst, New Hampshire); Zachary Darling (Somerville, Massachusetts) |
| ABSTRACT | Challenges of direct-to-Earth (DTE) laser communications (lasercom) between spacecraft in low-Earth orbit (LEO) or medium-Earth orbit (MEO) and ground terminals can include short duration transmission windows, long time gaps between the transmission windows, deleterious effects of atmospheric turbulence, and the inability to operate in cloudy weather. Direct-link optical communications systems described herein can have data rates that are high enough to empty high-capacity on-board buffer(s) (e.g., having a capacity of at least about 1 Tb to hundreds of Tb) of a spacecraft in a single pass lasting only tens of seconds to a few minutes (e.g., 1-15 minutes), and overprovisioning the buffer capacity accounts for variations in the latency between links. One or more distributed networks of compact optical ground terminals, connected via terrestrial data networks, receive and demodulate WDM optical data transmissions from a plurality of orbiting spacecraft (e.g., satellites). |
| FILED | Friday, January 08, 2016 |
| APPL NO | 14/991386 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 7/18513 (20130101) H04B 10/29 (20130101) H04B 10/40 (20130101) H04B 10/61 (20130101) H04B 10/118 (20130101) Original (OR) Class H04B 10/1121 (20130101) Multiplex Communication H04J 14/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003483 | Migliori et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin J. Migliori (San Diego, California); Daniel J. Gebhardt (San Diego, California); Daniel C. Grady (La Jolla, California); Riley Zeller-Townson (Hampstead, North Carolina) |
| ABSTRACT | Class types of input signals having unknown class types are automatically classified using a neural network. The neural network learns features associated with a plurality of different observed signals having respective different known class types. The neural network then recognizes features of the input signals having unknown class types that at least partially match at least some of the features associated with the plurality of different observed signals having respective different known class types. The neural network determines probabilities that each of the input signals has each of the known class types based on strengths of the matches between the recognized features of the input signals and the features associated with plurality of different observed signals. The neural network classifies each of the input signals as having one of the respective different known class types based on a highest determined probability. |
| FILED | Wednesday, May 03, 2017 |
| APPL NO | 15/586168 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/06 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Transmission H04B 1/0003 (20130101) H04B 17/309 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/0008 (20130101) H04L 27/0012 (20130101) Original (OR) Class H04L 27/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003751 | Hall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| INVENTOR(S) | John M. Hall (Stafford, Virginia); Richard A. Wright (Alexandria, Virginia); Brian J. Kowalewski (Fredericksburg, Virginia); Andrew J. Dotson (Alexandria, Virginia) |
| ABSTRACT | A multiple field of view dual band optical device with integrated calibration source is disclosed. Such an optical device is modular, and has a rotating electro-mechanical “tumbler” which houses two orthogonal Galilean afocal optical assemblies as well as at least one uniform temperature source. This modular device is intended to be inserted in front of a camera system which already has an imager optical assembly mated to a detector focal plane array. The disclosed modular device thus serves the purpose of providing to an existing dual-band camera imager up to four new optical fields of view as well as an integral calibration source, all of which can be electro-mechanically selected for viewing by a host camera imager. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/163749 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 15/14 (20130101) G02B 23/16 (20130101) Pictorial Communication, e.g Television H04N 5/332 (20130101) H04N 5/23296 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003985 | Holland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Gavin D. Holland (Oak Park, California); Michael D. Howard (Westlake Village, California); Tsai-Ching Lu (Thousand Oaks, California); Karim El Defrawy (Santa Monica, California); Matthew S. Keegan (Boston, Massachusetts); Kang-Yu Ni (Calabasas, California) |
| ABSTRACT | Described is a system for determining reliability of nodes in a mobile wireless network. The system is operable for receiving an Exploitation Network (Xnet) database. The Xnet database has an Xnet structure formed of a physical node layer (NetTopo), a network dependent (NetDep) layer, and an application dependent (AppDep) layer. The NetTopo layer includes NetTopo graphs reflecting connectivity between the nodes. The NetDep layer includes NetDep graphs reflecting connectivity dependencies amongst the nodes, and the AppDep layer includes Appdep graphs reflecting software application dependencies amongst the nodes. An Xnet Analytics Engine is run that monitors and evaluates reliability of each node in the mobile wireless network to provide a reliability estimate of each node. |
| FILED | Thursday, February 19, 2015 |
| APPL NO | 14/625988 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/147 (20130101) H04L 43/12 (20130101) H04L 43/045 (20130101) Wireless Communication Networks H04W 24/06 (20130101) Original (OR) Class H04W 24/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10004135 | Ilic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ognjen Ilic (Cambridge, Massachusetts); Ido Kaminer (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Yoav Lahini (Belmont, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ognjen Ilic (Cambridge, Massachusetts); Ido Kaminer (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Yoav Lahini (Belmont, Massachusetts) |
| ABSTRACT | A technique to guide a micro- or nano-scale particle uses the wavelengths of light beams to control the direction of motion of the particle. In this technique, an optical asymmetry is introduced into the particle to form a composite particle. The composite particle includes two faces that preferentially absorb light of different wavelengths, independent of the particle orientation. The difference in absorption spectra of the two faces creates a bidirectional and local thermal gradient that is externally switchable by changing the wavelength of the incident light beams. This thermal gradient induces a thermophoretic drift that moves the composite particle. A two-faced nanoparticle can be guided using the optically induced thermophoretic drift as the propulsion mechanism. |
| FILED | Wednesday, August 24, 2016 |
| APPL NO | 15/245641 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/076 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE46898 | Roland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Charles M. Roland (Waldorf, Maryland); Raymond M. Gamache (Indian Head, Maryland) |
| ABSTRACT | A coating of atactic polypropylene over a transparent armor substrate improves resistance to penetration while allowing convenient repair of minor abrasions and scratches. |
| FILED | Wednesday, May 03, 2017 |
| APPL NO | 15/585598 |
| ART UNIT | 3993 — Central Reexamination Unit (Mechanical) |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0407 (20130101) F41H 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 09999363 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Kedar G. Shah (San Francisco, California); Sarah H. Felix (Oakland, California); Satinderpall S. Pannu (Pleasanton, California); Vanessa Tolosa (Oakland, California); Angela C. Tooker (Dublin, California) |
| ABSTRACT | A modular, high density electrical system is disclosed which makes use of an interface component, which is well suited to being placed in contact with an anatomy of either a human or an animal, and which may be releasably coupled to an electronics module subsystem. The interface component has a plurality of electrically conductive interconnect pads that may be releasably secured by a member to a plurality of electrically conductive pads of the electronics module subsystem. The electronics module subsystem may have a substrate which supports both an electronics circuit and the interconnect pads. |
| FILED | Monday, April 13, 2015 |
| APPL NO | 14/684673 |
| ART UNIT | 3766 — Organic Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/04001 (20130101) Original (OR) Class A61B 2560/045 (20130101) A61B 2560/0214 (20130101) A61B 2562/166 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/3787 (20130101) A61N 1/37211 (20130101) A61N 1/37229 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000026 | Matsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marc R. Matsen (Seattle, Washington); Mark A Negley (Bellevue, Washington) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Marc R. Matsen (Seattle, Washington); Mark A Negley (Bellevue, Washington) |
| ABSTRACT | A composite induction consolidation apparatus includes a base mandrel and a ferromagnetic base mandrel facesheet having a specific Curie temperature carried by the base mandrel. The base mandrel facesheet is adapted to support a composite part and allow ambient air pressure to compact the composite part against the base mandrel facesheet. At least one magnetic induction coil is provided in the base mandrel. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/082532 |
| ART UNIT | 3742 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/06 (20130101) B29C 35/0227 (20130101) B29C 35/0805 (20130101) B29C 70/46 (20130101) Original (OR) Class B29C 2035/0811 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000377 | Stavila et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Vitalie Stavila (Pleasanton, California); Leonard E. Klebanoff (Dublin, California) |
| ABSTRACT | Nanostructured metal amides and nitrides are incorporated into nanoporous templates, such as carbon, using liquid ammonia as a solvent/reagent. This leads to unexpected improvements in metal amide nanoconfined hydrogen storage materials. The resulting nanostructured materials may reversibly absorb and desorb large capacities of hydrogen under conditions that are much milder compared to what has been achieved with bulk materials. In addition, the nanoconfined materials may reduce the amounts of ammonia released upon dehydriding, which may make the released hydrogen gas purer and may limit the capacity loss. In addition, nanoconfinement may simplify the reaction mechanism, eliminating undesired metal imide intermediates and promote hydrogen cycling under mild conditions. The liquid ammonia method also allows the simultaneous introduction of catalytic additives along with the parent hydrogen storage material. |
| FILED | Tuesday, August 23, 2016 |
| APPL NO | 15/244762 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/04 (20130101) C01B 3/0078 (20130101) Original (OR) Class C01B 3/0084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000390 | Owens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Jeffery Ray Owens (Panama City, Florida); Derek Lovingood (Lynn Haven, Florida) |
| ABSTRACT | A method of synthesizing silica nanoparticles. The method includes hydrolyzing a silica precursor to form a plurality of monomers, each monomer of the plurality comprising a microwave reactive silicon species. The plurality of monomers is irradiated by an energy source configured to generate microwave frequency energy. Irradiation cases the plurality of monomers polymerize into a silica nanoparticle. |
| FILED | Thursday, May 29, 2014 |
| APPL NO | 14/290336 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/14 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 39/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/84 (20130101) C01P 2004/03 (20130101) C01P 2004/32 (20130101) C01P 2004/52 (20130101) C01P 2004/64 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/08 (20130101) D06M 11/79 (20130101) D06M 23/08 (20130101) D06M 2101/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2933 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000698 | Cherepy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Siemens Medical Solutions USA, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Nerine Cherepy (Piedmont, California); Stephen A. Payne (Castro Valley, California); Zachary Seeley (Livermore, California); Peter Carl Cohen (Knoxville, Tennessee); Mark S. Andreaco (Knoxville, Tennessee); Matthias J. Schmand (Lenior City, Tennessee) |
| ABSTRACT | In one embodiment, a method includes forming a powder having a composition with the formula: AhBiCjO12, where h is 3±10%, i is 2±10%, j is 3±10%, A includes one or more rare earth elements, B includes aluminum and/or gallium, and C includes aluminum and/or gallium. The method additionally includes consolidating the powder to form an optically transparent ceramic, and applying at least one thermodynamic process condition during the consolidating to reduce oxygen and/or thermodynamically reversible defects in the ceramic. In another embodiment, a scintillator includes (Gd3-a-cYa)x(Ga5-bAlb)yO12Dc, where a is from about 0.05-2, b is from about 1-3, x is from about 2.8-3.2, y is from about 4.8-5.2, c is from about 0.003-0.3, and D is a dopant, and where the scintillator is an optically transparent ceramic scintillator having physical characteristics of being formed from a ceramic powder consolidated in oxidizing atmospheres. |
| FILED | Tuesday, March 08, 2016 |
| APPL NO | 15/064509 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/6267 (20130101) C04B 2235/6583 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7774 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/249 (20130101) G01T 1/2002 (20130101) G01T 1/2018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000787 | Timmins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico); LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico); LOS ALAMOS NATIONAL SECURITY, LLC. (Los Alamos, New Mexico) |
| INVENTOR(S) | Graham Timmins (Albuquerque, Minnesota); Louis Pete Silks (Los Alamos, New Mexico) |
| ABSTRACT | The present invention is directed to methods of determining the presence or absence of a bacterial infection in a patient using isotopically-labeled tyrosine and/or isotopically-labeled p-hydroxyphenylacetic acid. |
| FILED | Tuesday, October 08, 2013 |
| APPL NO | 14/434509 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/207 (20130101) A61B 5/0836 (20130101) A61B 5/14507 (20130101) A61B 5/14546 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/04 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/497 (20130101) G01N 33/56911 (20130101) G01N 2333/33 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001298 | Ermanoski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Ivan Ermanoski (Albuquerque, New Mexico); James E. Miller (Albuquerque, New Mexico) |
| ABSTRACT | Methods for controlling or operating solar thermochemical reactions process that maximize the two-step thermochemical energy cycle efficiency by a combination of pressure and temperature swing are disclosed. |
| FILED | Tuesday, December 08, 2015 |
| APPL NO | 14/962307 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/061 (20130101) C01B 31/20 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/02 (20130101) F24J 2/42 (20130101) Original (OR) Class F24J 2/402 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001571 | Rowland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Mark S Rowland (Alamo, California); Neal J Snyderman (Berkeley, California) |
| ABSTRACT | A neutron detector system and method for discriminating fissile material from non-fissile material wherein a digital data acquisition unit collects data at high rate, and in real-time processes large volumes of data directly into information that a first responder can use to discriminate materials. The system comprises counting neutrons from the unknown source and detecting excess grouped neutrons to identify fission in the unknown source. Comparison of the observed neutron count distribution with a Poisson distribution is performed to distinguish fissile material from non-fissile material. |
| FILED | Wednesday, October 15, 2014 |
| APPL NO | 14/515321 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/167 (20130101) G01T 3/00 (20130101) Original (OR) Class Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001612 | Zediker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Foro Energy, Inc. (Houston, Texas) |
| ASSIGNEE(S) | Foro Energy, Inc. (Littleton, Colorado) |
| INVENTOR(S) | Mark S. Zediker (Castle Rock, Colorado); Charles C. Rinzler (Boston, Massachusetts); Brian O. Faircloth (Evergreen, Colorado); Joel F. Moxley (Highlands Ranch, Colorado) |
| ABSTRACT | There is provided a system and apparatus for the transmission of high power laser energy over great distances without substantial power loss and without the presence of stimulated Raman scattering. There is further provided systems and optical fiber cable configurations and optical fiber structures for the delivering high power laser energy over great distances to a tool or surface to perform an operation or work with the tool or upon the surface. |
| FILED | Friday, May 13, 2016 |
| APPL NO | 15/154718 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 7/14 (20130101) E21B 7/15 (20130101) E21B 10/60 (20130101) E21B 17/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/443 (20130101) G02B 6/02395 (20130101) G02B 6/4296 (20130101) Original (OR) Class G02B 6/4415 (20130101) G02B 6/4436 (20130101) G02B 6/4492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002328 | Gamble, IV et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | John King Gamble, IV (Albuquerque, New Mexico); Malcolm S. Carroll (Albuquerque, New Mexico) |
| ABSTRACT | A silicon metal-oxide semiconductor device transports a spin-polarized single electron. An array of silicon quantum dot electrodes is arranged atop a silicon dioxide layer of a silicon metal-oxide semiconductor. The array comprises at least a first electrode and a second electrode adjacent to the first electrode. A transport control logic for individually controls a voltage applied to the electrodes. The transport control logic is configured to gradually decrease a voltage at the first electrode while gradually increasing a voltage at the second electrode. Localization of the single electron is adiabatically transferred from the first electrode to the second electrode while maintaining a desired energy gap between a ground state and a first excited state of the single electron. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/381819 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/413 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002694 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minnepolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Yanfeng Jiang (Minneapolis, Minnesota); Md Aminul Mehedi (Minneapolis, Minnesota) |
| ABSTRACT | An inductor may include a magnetic material that may include α″-Fe16(NxZ1-x)2 or α′-Fe8(NxZ1-x), or a mixture of at least one of α″-Fe16N2 or α′-Fe8N and at least one of α″-Fe16Z2 or α′-Fe8Z, where Z includes at least one of C, B, or O, and x is a number greater than zero and less than one. In some examples, the magnetic material may include a relatively high magnetic saturation, such as greater than about 200 emu/gram, greater than about 242 emu/gram, or greater than about 250 emu/gram. In addition, in some examples, the magnetic material may include a relatively low coercivity or magnetocrystalline anisotropy. Techniques for forming the inductor including the magnetic material are also described. |
| FILED | Friday, August 07, 2015 |
| APPL NO | 14/821520 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/065 (20130101) H01F 1/0302 (20130101) Original (OR) Class H01F 17/0006 (20130101) H01F 17/0013 (20130101) H01F 41/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002696 | Stelzer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Magnet Lab, Inc. (Palm Bay, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerald Stelzer (Palm Bay, Florida); Rainer Meinke (Melbourne, Florida); Mark Senti (Malabar, Florida) |
| ABSTRACT | A conductor assembly and method for constructing an assembly of the type which, when conducting current, generates a magnetic field or which, in the presence of a changing magnetic field, induces a voltage. In one embodiment the method provides a first insulative layer tubular in shape and including a surface along which a conductor segment may be positioned. A channel formed in the surface of the insulative layer defines a first conductor path and includes a surface of first contour in cross section along a first plane transverse to the conductor path. A segment of conductor having a surface of second contour in cross section is positioned at least partly in the channel and extends along the conductor path. Along the first plane, contact between the conductor surface of second contour and the channel surface of first contour includes at least two separate regions of contact. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 14/554255 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/288 (20130101) G01R 33/3802 (20130101) G01R 33/3815 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 5/06 (20130101) Original (OR) Class H01F 6/02 (20130101) H01F 6/06 (20130101) H01F 7/20 (20130101) H01F 41/04 (20130101) H01F 41/071 (20160101) H01F 41/086 (20160101) H01F 41/098 (20160101) Technical Subjects Covered by Former US Classification Y10T 29/4902 (20150115) Y10T 29/49014 (20150115) Y10T 29/49073 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002919 | Deligianni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Hariklia Deligianni (Alpine, New York); William J. Gallagher (Ardsley, New York); Maurice Mason (Danbury, Connecticut); Eugene J. O'Sullivan (Nyack, New York); Lubomyr T. Romankiw (Briancliff Manor, New York); Naigang Wang (Ossining, New York) |
| ABSTRACT | An on-chip magnetic structure includes a palladium activated seed layer and a substantially amorphous magnetic material disposed onto the palladium activated seed layer. The substantially amorphous magnetic material includes nickel in a range from about 50 to about 80 atomic % (at. %) based on the total number of atoms of the magnetic material, iron in a range from about 10 to about 50 at. % based on the total number of atoms of the magnetic material, and phosphorous in a range from about 0.1 to about 30 at. % based on the total number of atoms of the magnetic material. The magnetic material can include boron in a range from about 0.1 to about 5 at. % based on the total number of atoms of the magnetic material. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/698186 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/047 (20130101) H01F 41/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/288 (20130101) H01L 23/5227 (20130101) H01L 23/53242 (20130101) H01L 28/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002983 | Spoerke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Jaime C. Grunlan (College Station, Texas) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Erik David Spoerke (Albuquerque, New Mexico); Margaret Ellen Gordon (Albuquerque, New Mexico); Eric John Schindelholz (Albuquerque, New Mexico); Kenneth Miguel Armijo (Albuquerque, New Mexico); Neil R. Sorensen (Albuquerque, New Mexico); Anthony Martino (Albuquerque, New Mexico); Jaime C. Grunlan (College Station, Texas) |
| ABSTRACT | Polymer-clay nanocomposites thin film coatings have improved water vapor and oxygen permeability, in addition to improved corrosion resistance, while retaining high transparency, high electrical resistivity, and excellent fire-retardant properties for use as encapsulants for photovoltaic module assemblies and barrier coatings in other photovoltaic applications. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 15/603877 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/346 (20130101) Compositions of Macromolecular Compounds C08L 33/02 (20130101) C08L 79/02 (20130101) C08L 2203/204 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0481 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002998 | Kanatzidis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mercouri G. Kanatzidis (Wilmette, Illinois); Li-Dong Zhao (Beijing, China PRC) |
| ABSTRACT | Thermoelectric materials and thermoelectric cells and devices incorporating the thermoelectric materials are provided. Also provided are methods of using the cells and devices to generate electricity and to power external electronic devices. The thermoelectric materials comprise SnSe single crystals, including hole doped SnSe single crystals. |
| FILED | Tuesday, August 11, 2015 |
| APPL NO | 14/823738 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003059 | Duoss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Eric B. Duoss (Dublin, California); Patrick G. Campbell (Oakland, California); William C. Floyd, III (Oakland, California); Julie A. Jackson (Livermore, California); Matthew Merrill (Dublin, California); Conner T. Sharpe (Tracy, California); Christopher M. Spadaccini (Oakland, California); Michael Stadermann (Pleasanton, California); Cheng Zhu (Livermore, California) |
| ABSTRACT | A separator made of ion conductive ink is produced by additive manufacturing. A micro-battery is produced with the separator made of ion conductive ink located between the battery's anode and cathode. The separator functions to keep the anode and cathode apart and to facilitate the transport of ions to produce an operative micro-battery. |
| FILED | Tuesday, October 13, 2015 |
| APPL NO | 14/882127 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/18 (20130101) H01M 2/145 (20130101) H01M 2/1653 (20130101) Original (OR) Class H01M 2/1673 (20130101) H01M 6/40 (20130101) H01M 10/0436 (20130101) H01M 10/0525 (20130101) H01M 2220/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003068 | Lopez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Envia Systems, Inc. (Newark, California) |
| ASSIGNEE(S) | Zenlabs Energy, Inc. (Fremont, California) |
| INVENTOR(S) | Herman A. Lopez (Sunnyvale, California); Yogesh Kumar Anguchamy (Newark, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Charan Masarapu (Fremont, California); Subramanian Venkatachalam (Pleasanton, California); Sujeet Kumar (Newark, California) |
| ABSTRACT | High capacity silicon based anode active materials are described for lithium ion batteries. These materials are shown to be effective in combination with high capacity lithium rich cathode active materials. Supplemental lithium is shown to improve the cycling performance and reduce irreversible capacity loss for at least certain silicon based active materials. In particular silicon based active materials can be formed in composites with electrically conductive coatings, such as pyrolytic carbon coatings or metal coatings, and composites can also be formed with other electrically conductive carbon components, such as carbon nanofibers and carbon nanoparticles. Additional alloys with silicon are explored. |
| FILED | Friday, September 11, 2015 |
| APPL NO | 14/851405 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/12 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) Original (OR) Class H01M 4/364 (20130101) H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/587 (20130101) H01M 4/621 (20130101) H01M 4/622 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) H01M 2220/30 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003083 | Jung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LG Fuel Cell Systems, Inc. (North Canton, Ohio); University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | LG Fuel Cell Systems, Inc. (North Canton, Ohio); University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Hwa Young Jung (Canton, Ohio); Zhengliang Xing (North Canton, Ohio); Zhien Liu (Canton, Ohio); Richard W. Goettler (Medina, Ohio); Xiao-Dong Zhou (Irmo, South Carolina); Emir Dogdibegovic (West Columbia, South Carolina) |
| ABSTRACT | In some examples, a fuel cell including an anode; electrolyte; and cathode separated from the anode by the electrolyte, wherein the cathode includes a Pr-nickelate based material with (Pr1-xAx)n+1(Ni1-yBy)nO3n+1+δ as a general formula, where n is 1 as an integer, A is an A-site dopant including of a metal of a group formed by one or more lanthanides, and B is a B-site dopant including of a metal of a group formed by one or more transition metals, wherein the A and B-site dopants are provided such that there is an increase in phase-stability and reduction in degradation of the Pr-nickelate based material, and A is at least one metal cation of lanthanides, La, Nd, Sm, or Gd, B is at least one metal cation of transition metals, Cu, Co, Mn, Zn, or Cr, where: 0<x<1, and 0<y≤0.4. |
| FILED | Tuesday, July 21, 2015 |
| APPL NO | 14/805279 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/01 (20130101) C04B 2235/76 (20130101) C04B 2235/80 (20130101) C04B 2235/768 (20130101) C04B 2235/3213 (20130101) C04B 2235/3224 (20130101) C04B 2235/3227 (20130101) C04B 2235/3241 (20130101) C04B 2235/3262 (20130101) C04B 2235/3274 (20130101) C04B 2235/3275 (20130101) C04B 2235/3279 (20130101) C04B 2235/3281 (20130101) C04B 2235/3284 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9033 (20130101) Original (OR) Class H01M 8/004 (20130101) H01M 8/006 (20130101) H01M 8/0217 (20130101) H01M 8/0236 (20130101) H01M 8/1231 (20160201) H01M 8/1246 (20130101) H01M 2008/1293 (20130101) H01M 2300/0071 (20130101) H01M 2300/0074 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/525 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/56 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003237 | Sanders et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amber Kinetics, Inc. (Union City, California) |
| ASSIGNEE(S) | Amber Kinetics, Inc. (Union City, California) |
| INVENTOR(S) | Seth Sanders (Berkeley, California); Eric Sun (Union City, California); Mike He (San Jose, California); Matthew Senesky (Berkeley, California); Edward Chiao (San Jose, California) |
| ABSTRACT | A solid steel flywheel rotor having improved material properties offers improved energy storage at reduced cost. A process for manufacturing the rotor is also provided. |
| FILED | Tuesday, August 26, 2014 |
| APPL NO | 14/469382 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/005 (20130101) C21D 9/0068 (20130101) C21D 2261/00 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 15/00 (20130101) Dynamo-electric Machines H02K 7/025 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 09999369 | Ziaie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Babak Ziaie (West Lafayette, Indiana); Ronald A. Siegel (Minneapolis, Minnesota) |
| ABSTRACT | A method of making a sensor includes depositing a layer of hydrogel over a substrate, the hydrogel configured to change thickness or volume in response to a selected condition and including a plurality of magnetic particles disposed in the hydrogel so that a magnetic property of the hydrogel changes with changes of thickness or volume of the hydrogel. The hydrogel is sacrificed in selected region(s) of the layer so that the hydrogel outside the selected region(s) forms a plurality of spaced-apart islands of the hydrogel. The islands of the hydrogel are enclosed in an enclosure at least partly permeable to a selected fluid. A sensor for detecting a condition includes the substrate, islands, and a device coil arranged with respect to the hydrogel so that changes in the magnetic property modulate an electrical property of the sensor. A system includes the substrate, islands, and a magnetic-field detector. |
| FILED | Monday, December 01, 2014 |
| APPL NO | 14/557247 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) Original (OR) Class A61B 5/0031 (20130101) A61B 5/14503 (20130101) A61B 5/14532 (20130101) A61B 5/14539 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0009 (20130101) A61K 47/32 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 3/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49155 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000384 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Xianfan Xu (West Lafayette, Indiana); Dapeng Wei (Chongqing, China PRC); Peide Ye (West Lafayette, Indiana) |
| ABSTRACT | A method of forming single and few layer graphene on a quartz substrate in one embodiment includes providing a quartz substrate, melting a portion of the quartz substrate, diffusing a form of carbon into the melted portion to form a carbon and quartz mixture, and precipitating at least one graphene layer out of the carbon and quartz mixture. |
| FILED | Thursday, May 30, 2013 |
| APPL NO | 13/906057 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000443 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OHIO UNIVERSITY (Athens, Ohio) |
| ASSIGNEE(S) | Ohio University (Athens, Ohio) |
| INVENTOR(S) | Xiaozhuo Chen (Athens, Ohio); Stephen Bergmeier (Athens, Ohio) |
| ABSTRACT | Glucose deprivation is an attractive strategy in cancer research and treatment. Cancer cells upregulate glucose uptake and metabolism for maintaining accelerated growth and proliferation rates. Specifically blocking these processes is likely to provide new insights to the role of glucose transport and metabolism in tumorigenesis, as well as in apoptosis. As solid tumors outgrow the surrounding vasculature, they encounter microenvironments with a limited supply of nutrients leading to a glucose deprived environment in some regions of the tumor. Cancer cells living in the glucose deprived environment undergo changes to prevent glucose deprivation-induced apoptosis. Knowing how cancer cells evade apoptosis induction is also likely to yield valuable information and knowledge of how to overcome the resistance to apoptosis induction in cancer cells. Disclosed herein are novel anticancer compounds that inhibit basal glucose transport, resulting in tumor suppression and new methods for the study of glucose deprivation in animal cancer research. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 14/935902 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/09 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 39/367 (20130101) C07C 43/23 (20130101) C07C 43/253 (20130101) C07C 205/32 (20130101) Original (OR) Class C07C 211/48 (20130101) C07C 235/56 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 231/12 (20130101) C07D 233/64 (20130101) C07D 235/18 (20130101) C07D 249/08 (20130101) C07D 311/16 (20130101) C07D 311/82 (20130101) C07D 319/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000605 | Banister et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MEDIPACS, INC (San Diego, California); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | MEDIPACS, INC. (Tucson, Arizona); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Mark Banister (Tucson, Arizona); Yordan Geronov (Tucson, Arizona); Dominic McGrath (Tucson, Arizona) |
| ABSTRACT | A three-dimensional smart polymer matrix is formed by a first epoxy chemical reaction linking a linear polymer chain and a branched polymer chain, wherein the polymer chains are flexible and one or more reactive molecule species remain unreacted, at a predetermined mathematical ratio of reacted to un-reacted molecules and molecule species, and the un-reacted molecular species are available for further chemical reaction, protonation or deprotonation after the first chemical reaction. The resulting smart polymer matrix is hydrophilic and non-soluble to a solvent or electrolyte. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 14/385403 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/22 (20130101) C08G 59/504 (20130101) C08G 65/2624 (20130101) Original (OR) Class C08G 83/004 (20130101) C08G 2650/50 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) C08L 63/00 (20130101) C08L 67/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000608 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Jianjun Cheng (Urbana, Illinois); Hanze Ying (Urbana, Illinois) |
| ABSTRACT | The disclosure provides reversible polymers from polyurea by modifying the nitrogen atom with hindered substituents. The reversibility of hindered urea bond (HUB) can be controlled by changing the bulkiness of the substituents, and N-tert-butyl-N-ethylurea (TBEU), with its high binding constant and short lifetime, is applicable in the design of reversible polymer and self-healing materials at mild temperatures without external stimuli. HUB can be used in the design of smart materials with its adjustable reversibility, facile synthesis, and compatibility with many other polymer structures. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776104 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/757 (20130101) C08G 18/758 (20130101) C08G 18/833 (20130101) C08G 18/3206 (20130101) C08G 18/3228 (20130101) C08G 18/3246 (20130101) C08G 18/3278 (20130101) C08G 71/02 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/04 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 175/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000645 | Hardin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PLANT PV, Inc. (Alameda, California) |
| ASSIGNEE(S) | PLANT PV, Inc. (Alameda, California) |
| INVENTOR(S) | Brian E. Hardin (San Carlos, California); Erik Sauar (Oslo, Norway); Dhea Suseno (Oakland, California); Jesse J. Hinricher (Pipestone, Minnesota); Jennifer Huang (Saratoga, California); Tom Yu-Tang Lin (Berkeley, California); Stephen T. Connor (San Francisco, California); Daniel J. Hellebusch (Oakland, California); Craig H. Peters (Belmont, California) |
| ABSTRACT | A method of forming a fired multilayer stack are described. The method involves the steps of a) applying a wet metal particle layer on at least a portion of a surface of a substrate, b) drying the wet metal particle layer to form a dried metal particle layer, c) applying a wet intercalation layer directly on at least a portion of the dried metal particle layer to form a multilayer stack, d) drying the multilayer stack, and e) co-firing the multilayer stack to form the fired multilayer stack. The intercalating layer may include one or more of low temperature base metal particles, crystalline metal oxide particles, and glass frit particles. The wet metal particle layer may include aluminum, copper, iron, nickel, molybdenum, tungsten, tantalum, titanium, steel or combinations thereof. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360959 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0016 (20130101) B23K 35/025 (20130101) B23K 35/286 (20130101) B23K 35/3006 (20130101) B23K 35/3612 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 8/16 (20130101) C03C 8/18 (20130101) C03C 2205/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/24 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/049 (20141201) H01L 31/0201 (20130101) H01L 31/0203 (20130101) H01L 31/1804 (20130101) H01L 31/022425 (20130101) H01L 31/022433 (20130101) H01L 31/022441 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/34 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000733 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Anne Elizabeth Arnold (Tucson, Arizona); Kayla Arendt (Tucson, Arizona); David A. Baltrus (Tucson, Arizona) |
| ABSTRACT | Described herein are methods for the alteration and/or transfer of fungal functional traits, e.g., phenotypic activity, via the controlled transfer of endohyphal symbionts, e.g., bacteria, among fungal species. Also described are methods for the identification of endohyphal bacterial symbionts as determinants of cellulase and ligninase activity in fungi, and the use of endohyphal bacterial symbionts to alter the activity, including cellulase and ligninase activities, of the fungi. In particular, the fungi described herein are endophytic fungi, that is, fungi which colonize living, and subsequently senescent, plant tissue. |
| FILED | Friday, June 19, 2015 |
| APPL NO | 14/745365 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) Original (OR) Class C12N 1/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56961 (20130101) G01N 2333/37 (20130101) G01N 2333/942 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001472 | Wan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Qun Wan (Watervliet, New York); Amanda S. Chin (Glendale, New York) |
| ABSTRACT | Described herein is a method for determining chirality of a cell. The method includes culturing a cell on a base layer having a cell growth material. The method includes forming a top layer on the base layer after the cell has attached to the base layer, the top layer having a cell growth material. The base layer and the top layer form a graded 3D substrate. The intrinsic bias of the cell is determined from the directionality of spontaneous cell rotation. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/191787 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/5091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001473 | Bazan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (San Diego, California); Shu Wang (Beijing, China PRC); Bin Liu (Goleta, California) |
| ABSTRACT | Light harvesting luminescent multichromophores that are configured upon excitation to transfer energy to, and amplify the emission from, an acceptor signaling chromophore in energy-receiving proximity therewith are provided. Also provided are compositions for labelling a target. The labelling composition may include a donor light harvesting multichromophore and an acceptor signaling chromophore in energy-receiving proximity to the donor light harvesting multichromophore. Also provided is an aqueous composition for labelling a target, including: a donor light harvesting multichromophore; an acceptor signaling chromophore in energy-receiving proximity therewith; and a sensor biomolecule. Methods for using the subject compositions are also provided. |
| FILED | Thursday, March 16, 2017 |
| APPL NO | 15/461426 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 69/103 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/02 (20130101) C09K 11/06 (20130101) C09K 2211/1416 (20130101) C09K 2211/1425 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001475 | Bazan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (San Diego, California); Shu Wang (Beijing, China PRC); Bin Liu (Goleta, California) |
| ABSTRACT | Light harvesting luminescent multichromophores that are configured upon excitation to transfer energy to, and amplify the emission from, an acceptor signaling chromophore in energy-receiving proximity therewith are provided. Also provided are compositions for labelling a target. The labelling composition may include a donor light harvesting multichromophore and an acceptor signaling chromophore in energy-receiving proximity to the donor light harvesting multichromophore. Also provided is an aqueous composition for labelling a target, including: a donor light harvesting multichromophore; an acceptor signaling chromophore in energy-receiving proximity therewith; and a sensor biomolecule. Methods for using the subject compositions are also provided. |
| FILED | Tuesday, February 17, 2015 |
| APPL NO | 14/624466 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) C12Q 1/6818 (20130101) C12Q 1/6818 (20130101) C12Q 2525/107 (20130101) C12Q 2525/107 (20130101) C12Q 2527/125 (20130101) C12Q 2565/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) Original (OR) Class G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002460 | Black et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Michael J. Black (Providence, Rhode Island); Alexandru O. Balan (Pawtucket, Rhode Island); Alexander W. Weiss (Shirley, Massachusetts); Leonid Sigal (Pittsburgh, Pennsylvania); Matthew M. Loper (Providence, Rhode Island); Timothy S. St. Clair (Cambridge, Massachusetts) |
| ABSTRACT | A system and method of estimating the body shape of an individual from input data such as images or range maps. The body may appear in one or more poses captured at different times and a consistent body shape is computed for all poses. The body may appear in minimal tight-fitting clothing or in normal clothing wherein the described method produces an estimate of the body shape under the clothing. Clothed or bare regions of the body are detected via image classification and the fitting method is adapted to treat each region differently. Body shapes are represented parametrically and are matched to other bodies based on shape similarity and other features. Standard measurements are extracted using parametric or non-parametric functions of body shape. The system components support many applications in body scanning, advertising, social networking, collaborative filtering and Internet clothing shopping. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 14/885333 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) G06K 9/6221 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0601 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 7/77 (20170101) G06T 17/00 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003110 | Ye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Meng Ye (Stanford, California); Yi Cui (Stanford, California); Mauro Pasta (Ubiale Clanezzo, Italy); Xing Xie (Pasadena, California); Craig S. Criddle (Stanford, California); Vaishnav V. Davey (Stanford, California) |
| ABSTRACT | Described herein is a mixing entropy battery including a cationic electrode for sodium ion exchange and an anionic electrode for chloride ion exchange, where the cationic electrode includes at least one Prussian Blue material, and where the mixing entropy battery is configured to convert salinity gradient into electricity. |
| FILED | Tuesday, May 17, 2016 |
| APPL NO | 15/157126 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/227 (20130101) H01M 10/36 (20130101) H01M 10/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10003317 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Xiuling Li (Champaign, Illinois); Moyang Li (Urbana, Illinois); Wen Huang (Champaign, Illinois) |
| ABSTRACT | A tubular resonant filter comprises a multilayer sheet in a rolled configuration comprising multiple turns about a longitudinal axis, where the multilayer sheet includes a strain-relieved layer, a patterned first conductive layer on the strain-relieved layer, an insulating layer on the patterned first conductive layer, and a patterned second conductive layer on the insulating layer and the patterned first conductive layer. The patterned first and second conductive layers and the insulating layer are interrelated to form a rolled-up inductor connected to a rolled-up capacitor on the strain-relieved layer. |
| FILED | Thursday, April 07, 2016 |
| APPL NO | 15/092979 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/0115 (20130101) Original (OR) Class H03H 2001/005 (20130101) H03H 2001/0042 (20130101) H03H 2001/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10004135 | Ilic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ognjen Ilic (Cambridge, Massachusetts); Ido Kaminer (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Yoav Lahini (Belmont, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ognjen Ilic (Cambridge, Massachusetts); Ido Kaminer (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Yoav Lahini (Belmont, Massachusetts) |
| ABSTRACT | A technique to guide a micro- or nano-scale particle uses the wavelengths of light beams to control the direction of motion of the particle. In this technique, an optical asymmetry is introduced into the particle to form a composite particle. The composite particle includes two faces that preferentially absorb light of different wavelengths, independent of the particle orientation. The difference in absorption spectra of the two faces creates a bidirectional and local thermal gradient that is externally switchable by changing the wavelength of the incident light beams. This thermal gradient induces a thermophoretic drift that moves the composite particle. A two-faced nanoparticle can be guided using the optically induced thermophoretic drift as the propulsion mechanism. |
| FILED | Wednesday, August 24, 2016 |
| APPL NO | 15/245641 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/076 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10000036 | Kang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jin Ho Kang (Newport News, Virginia); Cheol Park (Yorktown, Virginia); Godfrey Sauti (Hampton, Virginia); Michael W. Smith (Newport News, Virginia); Kevin C. Jordan (Newport News, Virginia); Sharon E. Lowther (Hampton, Virginia); Robert G. Bryant (Williamsburg, Virginia) |
| ABSTRACT | Boron nitride nanotubes (BNNTs), boron nitride nanoparticles (BNNPs), carbon nontubes (CNTs), graphites, or their combinations, are incorporated into matrices of polymer, ceramic or metals. Fibers, yarns, and woven or nonwoven mates of BNNTs are uses as toughening layers in penetration resistant materials to maximize energy absorption and/or high hardness layers to rebound or deform penetrators. They can be also uses as reinforcing inclusions combining with other polymer matrices to create composite layer like typical reinforcing fibers such as Kevlar®, Spectra®, ceramics and metals. Enhanced wear resistance and prolonged usage time, even under harsh conditions, are achieved by adding boron nitride nanomaterials because both hardness and toughness are increased. Such materials can be used in high temperature environments since the oxidation temperature of BNNTs exceeds 800° C. in air. Boron nitride based composite materials are useful as strong structural materials for anti-micrometeorite layers for spacecraft and space suits, ultra strong tethers, protective gear for the human body as well as for vehicles, helmets, shields and safety suits/helmets for industry. |
| FILED | Monday, June 29, 2015 |
| APPL NO | 14/753848 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/26 (20130101) Original (OR) Class B32B 2260/046 (20130101) B32B 2262/0269 (20130101) B32B 2264/107 (20130101) B32B 2307/554 (20130101) B32B 2307/558 (20130101) B32B 2571/02 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) C08J 5/046 (20130101) C08J 2375/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/38 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0414 (20130101) F41H 5/0442 (20130101) F41H 5/0471 (20130101) F41H 5/0485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000413 | Abney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Morgan Barrera Abney (Athens, Alabama); James E. Alleman (Ames, Iowa) |
| ABSTRACT | A clinker for use in cement manufacturing includes a cement clinker mixture having crystals of an element that is less electronegative than carbon and carbon bonded to at least a portion of the crystals. |
| FILED | Wednesday, December 16, 2015 |
| APPL NO | 14/971757 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 22/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000419 | Hung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ching-Cheh Hung (Westlake, Ohio); Janet B. Hurst (Columbia Station, Ohio); Maricela Lizcano (Rocky River, Ohio); Diana Santiago (North Ridgeville, Ohio) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Ching-Cheh Hung (Westlake, Ohio); Janet B. Hurst (Columbia Station, Ohio); Maricela Lizcano (Rocky River, Ohio); Diana Santiago (North Ridgeville, Ohio) |
| ABSTRACT | Compositions and methods associated with intercalating and exfoliating a sample are described herein. For example, of a method may include mixing the sample with intercalation materials. The intercalation materials are then intercalated into the sample to obtain a sample intercalated with the intercalation materials. The intercalated sample can then be exfoliated to produce an exfoliated sample. |
| FILED | Monday, November 23, 2015 |
| APPL NO | 14/948581 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/583 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001063 | Suciu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Gabriel L. Suciu (Glastonbury, Connecticut); Jesse M. Chandler (South Windsor, Connecticut) |
| ABSTRACT | A propulsion system for an aircraft includes first and second turbine engines mounted within a fuselage of the aircraft. The first turbine engine includes a first engine core that drives a first propulsor disposed about a first propulsor axis. The second turbine engine includes a second engine core and a second propulsor disposed about a second propulsor axis parallel to the first propulsor axis. The first engine core and the second engine core are mounted at an angle relative to corresponding ones of the first and second propulsor axes. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 14/440698 |
| ART UNIT | 3748 — Fluid Handling and Dispensing |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/20 (20130101) B64D 33/02 (20130101) B64D 2033/0286 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/20 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/314 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10001085 | Isaac et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Orbital ATK, Inc. (Dulles, Virginia) |
| ASSIGNEE(S) | Orbital ATK, Inc. (Plymouth, Minnesota) |
| INVENTOR(S) | Clinton R. Isaac (North East, Maryland); Adam Naramore (Lancaster, Pennsylvania); Talbot P. Thrasher (Newark, Delaware); Michael D. Lajczok (Wilmington, Delaware); Joseph Bellotte (Christiansburg, Virginia) |
| ABSTRACT | A thrust-vectoring rocket motor nozzle includes a forward assembly having a forward shell with a flange configured for connection to a motor and a throat portion opposite the flange. A ball joint sleeve may be disposed proximate the throat portion, and an exit cone assembly may include a ball joint socket configured to mate with the ball joint sleeve to allow movement of the exit cone assembly about one or more axes relative to the forward assembly. A thermal barrier may be disposed in a gap between the forward assembly and the exit cone assembly. The forward assembly may include a throat insulator mechanically locked within the forward shell. Related methods include forming thrust-vectorable rocket motor nozzles. Rocket motors may include such nozzles. |
| FILED | Wednesday, September 24, 2014 |
| APPL NO | 14/495063 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Jet-propulsion Plants F02K 9/08 (20130101) F02K 9/84 (20130101) Original (OR) Class F02K 9/974 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) F05D 2230/40 (20130101) F05D 2230/60 (20130101) F05D 2240/55 (20130101) F05D 2260/231 (20130101) F05D 2300/44 (20130101) F05D 2300/603 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10000486 | Dai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kineta Four, LLC (Seattle, Washington) |
| ASSIGNEE(S) | Kineta Viral Hemorrhagic Fever, LLC (Seattle, Washington) |
| INVENTOR(S) | Dongcheng Dai (Corvallis, Oregon); James R. Burgeson (Albany, Oregon); Sean M. Amberg (Corvallis, Oregon); Dennis E. Hruby (Albany, Oregon) |
| ABSTRACT | Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/353351 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 209/08 (20130101) C07D 235/06 (20130101) C07D 235/08 (20130101) C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 405/10 (20130101) C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000543 | Schellenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amunix Operating Inc. (Mountain View, California) |
| ASSIGNEE(S) | Amunix Operating Inc. (Mountain View, California) |
| INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Willem P. Stemmer (Los Gatos, California); Chia-wei Wang (Milpitas, California); Nathan Geething (Santa Clara, California); Jeffrey L. Cleland (San Carlos, California) |
| ABSTRACT | The present invention relates to compositions comprising glucose regulating peptides linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of glucose regulating peptide-related diseases, disorders, and conditions. |
| FILED | Wednesday, November 30, 2016 |
| APPL NO | 15/365792 |
| ART UNIT | 1676 — Organic Chemistry |
| CURRENT CPC | Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2200/328 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/605 (20130101) Original (OR) Class C07K 2319/31 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000605 | Banister et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MEDIPACS, INC (San Diego, California); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | MEDIPACS, INC. (Tucson, Arizona); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Mark Banister (Tucson, Arizona); Yordan Geronov (Tucson, Arizona); Dominic McGrath (Tucson, Arizona) |
| ABSTRACT | A three-dimensional smart polymer matrix is formed by a first epoxy chemical reaction linking a linear polymer chain and a branched polymer chain, wherein the polymer chains are flexible and one or more reactive molecule species remain unreacted, at a predetermined mathematical ratio of reacted to un-reacted molecules and molecule species, and the un-reacted molecular species are available for further chemical reaction, protonation or deprotonation after the first chemical reaction. The resulting smart polymer matrix is hydrophilic and non-soluble to a solvent or electrolyte. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 14/385403 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/22 (20130101) C08G 59/504 (20130101) C08G 65/2624 (20130101) Original (OR) Class C08G 83/004 (20130101) C08G 2650/50 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) C08L 63/00 (20130101) C08L 67/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002979 | Yao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey) |
| INVENTOR(S) | Jie Yao (Plainsboro, New Jersey) |
| ABSTRACT | Disclosed are a semiconductor photodiode (PD) or phototransistor (PT) photo detector with a unipolarly doped edge region containing a portion of the photon absorption layer and occupying over 99% of the photo detector area as projected on a plane parallel to the semiconductor substrate. Embodiments also relate to methods of making the photo detector. |
| FILED | Tuesday, May 30, 2017 |
| APPL NO | 15/608685 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1446 (20130101) H01L 27/14649 (20130101) H01L 27/14681 (20130101) H01L 31/105 (20130101) H01L 31/1075 (20130101) H01L 31/1105 (20130101) H01L 31/1844 (20130101) H01L 31/03042 (20130101) H01L 31/03046 (20130101) H01L 31/03529 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 09999220 | Ballinger, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arkion Life Sciences, LLC (New Castle, Delaware) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia); ARKION LIFE SCIENCES, LLC (New Castle, Delaware) |
| INVENTOR(S) | Kenneth E. Ballinger, Jr. (Kennett Square, Pennsylvania); Scott John Werner (Wellington, Colorado) |
| ABSTRACT | The present disclosure relates to the use of polycyclic quinones, and particularly, anthraquinones, to non-lethally repel rodents from consuming or otherwise damaging vegetation, private property, man-made structures, or agricultural products in the field and in storage. Further, the invention shows use as a protection strategy for various other products used as a food source by certain rodents. |
| FILED | Tuesday, January 13, 2015 |
| APPL NO | 14/595718 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 35/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09999661 | Mahony |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE STATE OF QUEENSLAND ACTING THROUGH THE DEPARTMENT OF AGRICULTURE AND FISHERIES (Brisbane, Queensland, Australia); MEAT and LIVESTOCK AUSTRALIA LIMITED (, None) |
| ASSIGNEE(S) | The State of Queensland Acting Through the Department of Agriculture and Fisheries (Brisbane, Queensland, Australia); Meat and Livestock Australia Limited (North Sydney, New South Wales, Australia) |
| INVENTOR(S) | Timothy John Mahony (Bellbowrie, Australia) |
| ABSTRACT | The present disclosure teaches generally in the field of vaccination and disease control in cattle and bovine animals. A recombinant bovine herpesvirus 1 (BoHV-1) vaccine vector is provided for efficient control of one or more bovine pathogens such as those associated with bovine respiratory disease complex, such as bovine viral diarrhea virus (BVDV), and which ameliorates disease conditions caused thereby. Protocols for the management of confined or herded bovine animals are also enabled herein. |
| FILED | Tuesday, May 31, 2016 |
| APPL NO | 15/169555 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/102 (20130101) A61K 39/245 (20130101) A61K 2039/58 (20130101) A61K 2039/70 (20130101) A61K 2039/543 (20130101) A61K 2039/552 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/16734 (20130101) C12N 2710/16743 (20130101) C12N 2770/24334 (20130101) C12N 2770/24371 (20130101) C12N 2800/204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10000762 | Baerson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Scott R. Baerson (Oxford, Mississippi); Zhiqiang Pan (Oxford, Mississippi); James J Polashock (Hainesport, New Jersey) |
| ABSTRACT | Transcription regulatory elements, namely promoter and terminator sequences, obtained from Sorghum bicolor that drive RNA transcription predominately in root hair cells are described, as well as cassettes, expression vectors, and genetically modified plants containing these transcription regulatory elements. The genetically modified plants can be gymnosperms, dicots, or monocots. Methods of directing transcription of a heterologous polynucleotide under control of these transcription regulatory elements in a genetically modified plant's root hair cells are also provided. |
| FILED | Wednesday, May 20, 2015 |
| APPL NO | 14/717477 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10001410 | Baudelet |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Matthieu Baudelet (Orlando, Florida) |
| ABSTRACT | The current invention considers the spectrum as a multimodal distribution over a list of structures containing the wavelength as the main entry and the other information mentioned above in the list as additional entries. Each line is then given a probability of contributing to the spectral line. In the case of multiple spectral lines, inference between spectral lines and their respective levels of confidence will provide a complete picture of the list of probable emitters with a probability factor for each line in order to provide a quantitative assignment of the spectral lines and profiling for a given spectrum. |
| FILED | Friday, February 13, 2015 |
| APPL NO | 14/622046 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/28 (20130101) Original (OR) Class G01J 2003/283 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/718 (20130101) G01N 2021/3196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10001348 | Zickel |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Zickel (Qiryat Byalik, Israel) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Zickel (Qiryat Byalik, Israel) |
| ABSTRACT | A device for dismantling explosive devices, the device may include a handle for carrying the robot; a camera; infrared illumination elements; a payload compartment that is configured to hold, in a releasable manner, an explosive device dismantling payload; laser markers that are configured to be at a predefined spatial relationship with an optical axis of the explosive device dismantling payload; a transceiver; a controller that is configured to control the robot, at least partially in response to commands that are received by the transceiver; a base; and a rotation and tilt assembly for moving the payload compartment in relation to the base. The device may be without a driving unit for driving the device from one location to the other. |
| FILED | Monday, November 21, 2016 |
| APPL NO | 15/356849 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 11/0025 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10002430 | Mundhenk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Terrell N. Mundhenk (Dublin, California); A. Arturo Flores (San Diego, California); Howard Neely, III (Santa Monica, California); Michael J. Daily (Thousand Oaks, California) |
| ABSTRACT | Described is a training system for training a vision-based object detector. The system is configured to run an object detector on an image of a cleared scene to detect objects in the cleared scene. The object detector includes a support vector machine (SVM) or similar classifier with a feature model to generate an SVM score for object features and a spatial bias threshold to generate augmented object scores. The system designated detected objects in the cleared scene as false detections and, based on that, updates at least one of the feature model and spatial bias threshold to designate the false detections as background. The updated feature model or updated spatial bias threshold are then stored for use in object detection. |
| FILED | Thursday, April 28, 2016 |
| APPL NO | 15/141416 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Image Data Processing or Generation, in General G06T 7/0042 (20130101) Original (OR) Class G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 19, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180619.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page