FedInvent™ Patents

Patent Details for Tuesday, June 26, 2018 

This page was updated on Monday, March 27, 2023 at 05:34 AM GMT

Department of Health and Human Services (HHS) 

US 10004212 Welsh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Michael J. Welsh (Riverside, Iowa);  David Stoltz (Iowa City, Iowa)
ABSTRACT This invention relates to transgenic pig models of cystic fibrosis, cells that can be used to make such animals, and methods of making and using these pigs and cells.
FILED Monday, April 24, 2017
APPL NO 15/494738
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0276 (20130101)
A01K 67/0278 (20130101) Original (OR) Class
A01K 2207/15 (20130101)
A01K 2217/056 (20130101)
A01K 2217/072 (20130101)
A01K 2217/206 (20130101)
A01K 2227/108 (20130101)
A01K 2267/0306 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004395 Dana et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
INVENTOR(S) Reza Dana (Boston, Massachusetts);  Francisco L. Amparo Pulido (Boston, Massachusetts);  Haobing Wang (Boston, Massachusetts)
ABSTRACT The technology described in this document can be embodied in systems and computer-implemented methods for determining a score representing an amount of staining of the cornea. The methods include obtaining a digital image of the cornea stained with a tracer material, receiving a selection of a portion of the image, and processing, by a processing device, the selection to exclude areas with one or more artifacts to define an evaluation area. For each of a plurality of pixels within the evaluation area, a plurality of Cartesian color components are determined and a hue value in a polar coordinate based color space is calculated from the components. An amount of staining of the cornea is then determined as a function of the hue value. The methods also include assigning a score to the evaluation area based on the amount of staining calculated for the plurality of pixels.
FILED Friday, May 01, 2015
APPL NO 15/308184
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/14 (20130101)
A61B 3/0025 (20130101) Original (OR) Class
A61B 3/1025 (20130101)
A61B 5/0071 (20130101)
A61B 5/1032 (20130101)
A61B 5/4848 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004422 Alsop et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) David Alsop (Newton, Massachusetts);  Rachel Scheidegger (Boston, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center (Boston, Massachusetts)
INVENTOR(S) David Alsop (Newton, Massachusetts);  Rachel Scheidegger (Boston, Massachusetts)
ABSTRACT A method for chemical exchange saturation transfer (“CEST”) imaging that is more insensitive to off-resonance and magnetization transfer effects than other CEST methods is provided. Sn general, three different images are obtained: one obtained with radio frequency (“RF”) saturation about a labeling frequency, one obtained with RF saturation about a reference frequency, and one obtained with RF saturation about both the labeling and reference frequencies. This method, termed saturation with frequency alternating radiofrequency irradiation (“SAFARI”), is also very robust to magnetic field inhomogeneities. The three images, referred to as a labeled image, reference image, and dual frequency image, are selectively combined to produce an image of the subject in which CEST contrast is present, but errors arising from off-resonance and magnetization transfer effects are substantially suppressed.
FILED Monday, January 24, 2011
APPL NO 13/574876
ART UNIT 3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5601 (20130101)
G01R 33/5605 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004462 Ernst et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) KinetiCor, Inc. (Honolulu, Hawaii);  The University of Hawai'i (Honolulu, Hawaii);  The Queen's Medical Center (Honolulu, Hawaii)
ASSIGNEE(S) KinetiCor, Inc. (Honolulu, Hawaii);  The University of Hawai'i (Honolulu, Hawaii);  The Queen's Medical Center (Honolulu, Hawaii)
INVENTOR(S) Thomas Michael Ernst (Honolulu, Hawaii);  Benjamin Anton Zahneisen (Ottensoos, Germany);  Jeffrey N. Yu (Honolulu, Hawaii)
ABSTRACT The disclosure herein provides methods, systems, and devices for removing prospective motion correction from medical imaging scans. In an embodiment, a computer-implemented method for removing motion correction from biomedical imaging scan data comprises tracking, by a computer system, motion of an object being scanned; generating, by the computer system, motion tracking data; adjusting, by the computer system, a biomedical imaging scanner, using the motion tracking data, to compensate in real time for object motion, such that raw image data generated by the scanner can be reconstructed into motion-corrected images; inverting, by the computer system, the motion tracking data; and applying, by the computer system, the inverted motion tracking data to the raw image data to generate de-corrected image data representative of what the scanner would produce had the scanner not compensated for motion, wherein the de-corrected image data can be reconstructed into de-corrected images, wherein the computer system comprises an electronic memory and a computer processor.
FILED Monday, March 23, 2015
APPL NO 14/666049
ART UNIT 3737 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0013 (20130101)
A61B 5/055 (20130101)
A61B 5/721 (20130101) Original (OR) Class
A61B 6/032 (20130101)
A61B 6/463 (20130101)
A61B 6/527 (20130101)
A61B 6/5205 (20130101)
A61B 2034/2065 (20160201)
A61B 2560/0475 (20130101)
A61B 2560/0487 (20130101)
A61B 2576/00 (20130101)
A61B 2576/026 (20130101)

Image Data Processing or Generation, in General
G06T 5/003 (20130101)
G06T 5/50 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/30016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004586 Derwin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
ASSIGNEE(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
INVENTOR(S) Kathleen Anne Derwin (Shaker Heights, Ohio);  Anthony Calabro (Cleveland Heights, Ohio)
ABSTRACT Biocompatible tissue grafts are provided. The biocompatible tissue grafts include a bulk graft including a biocompatible material and having at least a first surface. The biocompatible tissue grafts also include a coating including a hydrogel and being immobilized on the bulk graft at the first surface. The biocompatible material includes at least one of a biologic material or a biologic-synthetic composite material. The hydrogel includes cross-linked hydroxyphenyl-substituted hyaluronan (HPS-HA), cross-linked hydroxyphenyl-substituted collagen (HPS-C), or both. The cross-linked HPS-HA, cross-linked HPS-C, or both have been formed by cross-linking of hydroxyphenyl groups of HPS-HA, HPS-C, or both to form dihydroxyphenyl bridges. Also disclosed are methods for repair of tissue damage in a subject in need thereof. The methods include surgically implanting the biocompatible tissue graft into a site of the tissue damage in the subject.
FILED Thursday, August 27, 2015
APPL NO 14/837658
ART UNIT 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/0063 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/34 (20130101)
A61L 27/34 (20130101)
A61L 27/52 (20130101)
A61L 27/3633 (20130101)
A61L 31/10 (20130101)
A61L 31/10 (20130101)
A61L 31/145 (20130101)

Compositions of Macromolecular Compounds
C08L 89/06 (20130101)
C08L 89/06 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2509/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004695 Reinhard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Bjoern Markus Reinhard (Brookline, Massachusetts);  Suryaram Gummuluru (Westwood, Massachusetts)
ABSTRACT Embodiments disclosed herein relates to ganglioside GM3-containing mixed lipids nanoparticles having an overall size between 60-100 nm, the making thereof and the uses. The nanoparticles selectively targeted to CD169+ expressing cells such as dendritic cells and macrophage. The nanoparticles are endocytosed by the CD169+ expressing cells.
FILED Wednesday, April 08, 2015
APPL NO 15/304127
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 9/1271 (20130101)
A61K 9/1272 (20130101)
A61K 9/5115 (20130101)
A61K 9/5123 (20130101) Original (OR) Class
A61K 9/5192 (20130101)
A61K 47/4823 (20130101)
A61K 47/48046 (20130101)
A61K 47/48815 (20130101)
A61K 47/48861 (20130101)
A61K 47/48884 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004701 Dunman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF ROCHESTER (Rochester, New York);  UNIVERSITY OF KANSAS (Lawrence, Kansas)
ASSIGNEE(S) UNIVERSITY OF ROCHESTER (Rochester, New York);  UNIVERSITY OF KANSAS (Lawrence, Kansas)
INVENTOR(S) Paul M. Dunman (Pittsford, New York);  Damian J. Krysan (Pittsford, New York);  Daniel P. Flaherty (Overland Park, Kansas)
ABSTRACT Provided herein are compositions and methods for treating or preventing infection.
FILED Monday, November 21, 2016
APPL NO 15/356940
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/66 (20130101)
A61K 31/138 (20130101) Original (OR) Class
A61K 31/445 (20130101)
A61K 31/566 (20130101)
A61K 31/4152 (20130101)
A61K 31/4515 (20130101)
A61K 31/4525 (20130101)
A61K 31/4545 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101)
C12Q 1/485 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004755 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Frederick National Laboratory for Cancer Research (FNLCR)
Federally Funded Research and Development Center (FFRDC)
Operated by Leidos Biomedical Research, Inc. (LBRI) at Frederick, MD
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Xiaodong Wang (Chapel Hill, North Carolina);  Weihe Zhang (Vestavia, Alabama);  Stephen Frye (Chapel Hill, North Carolina)
ABSTRACT Uses of pyrrolopyrimidines with anti-Mer tyrosine kinase activity as anti-infective agents, immunostimulatory and immunomodulatory agents, anti-cancer agents (including against MerTK−/− tumors and ITD and TKD mutant forms of Acute Myeloid Leukemia (AML)), and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms.
FILED Monday, January 30, 2017
APPL NO 15/419642
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101)
A61K 31/519 (20130101)
A61K 31/529 (20130101)
A61K 31/551 (20130101)
A61K 31/635 (20130101) Original (OR) Class
A61K 31/5377 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004764 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Janet S. Lee (Pittsburgh, Pennsylvania);  Timothy E. Corcoran (Pittsburgh, Pennsylvania);  Valerian Kagan (Pittsburgh, Pennsylvania)
ABSTRACT Cell-based therapies show considerable potential as an immunomodulatory strategy for a variety of lung diseases, including chronic obstructive pulmonary disease (COPD), asthma, bronchiolitis, acute lung injury, lung allograft rejection (acute or chronic), pulmonary fibrosis. Described herein is the development of red blood cell membrane-derived microparticles (RBC MPs), which are depleted of hemoglobin (Hb) and express phosphatidylserine on their surface, for the treatment of lung disease. Administration of RBC MPs to the lung via inhalation promotes the production of immunoregulatory cytokines (such as IL-10), and reduces inflammation and injury in the lung.
FILED Thursday, November 06, 2014
APPL NO 15/034700
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101)
A61K 9/0075 (20130101)
A61K 9/0078 (20130101)
A61K 9/127 (20130101)
A61K 35/18 (20130101) Original (OR) Class
A61K 2035/124 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
Y10S 977/906 (20130101)
Y10S 977/907 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004765 Lawrence et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Jeanne B. Lawrence (Mapleville, Rhode Island);  Jun Jiang (Shrewsbury, Massachusetts);  Lisa L. Hall (Framingham, Massachusetts)
ABSTRACT Methods and compositions for reducing expression of genes on Chromosome 21 (“Chr 21”) by targeting an XIST transgene to the Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) gene or a Regulator of calcineurin 1 (RCAN1) gene, and cells and transgenic animals comprising an XIST transgene inserted into a DYRK1A or RCAN1 allele, e.g., cells and animals trisomic for human Chr 21 and mouse Chr 16.
FILED Friday, March 14, 2014
APPL NO 14/776672
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0271 (20130101)
A01K 67/0275 (20130101)
A01K 2207/12 (20130101)
A01K 2217/15 (20130101)
A01K 2217/072 (20130101)
A01K 2217/203 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0318 (20130101)
A01K 2267/0356 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/28 (20130101) Original (OR) Class
A61K 48/005 (20130101)
A61K 48/0075 (20130101)
A61K 2035/124 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101)
C12N 15/85 (20130101)
C12N 15/111 (20130101)
C12N 15/907 (20130101)
C12N 15/1137 (20130101)
C12N 15/8509 (20130101)
C12N 2310/14 (20130101)
C12N 2310/111 (20130101)
C12N 2310/113 (20130101)
C12N 2330/51 (20130101)
C12N 2800/40 (20130101)
C12N 2810/10 (20130101)
C12N 2830/003 (20130101)
C12N 2830/32 (20130101)
C12N 2999/005 (20130101)

Enzymes
C12Y 207/12001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004766 Du et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Yiqin Du (Pittsburgh, Pennsylvania);  James L. Funderburgh (Pittsburgh, Pennsylvania);  Joel Steven Schuman (Pittsburgh, Pennsylvania)
ABSTRACT Provided herein are isolated populations of multipotent stem cells capable of differentiating into trabecular meshwork (TM) cells, methods of obtaining an isolated population of TM cells, and isolated populations of TM cells obtained therefrom. Compositions, kits, and devices comprising the isolated populations of multipotent stem cells or TM cells are also provided herein. Further provided are methods of using the compositions, kits, and devices for decreasing intraocular pressure in an eye, increasing cell density in a trabecular meshwork of an eye, increasing outflow of aqueous humor from an eye, or treating or preventing a medical condition in a subject.
FILED Monday, January 26, 2015
APPL NO 14/605216
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 35/30 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004767 Peltz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Gary Peltz (Redwood City, California);  Dan Xu (Fremont, California)
ABSTRACT Methods are provided for producing a population of hepatocyte-like cells (iHeps) from a population of adipocyte-derived stem cells (ASCs). Aspects of the methods include placing a population of ASCs into a three dimensional culture (e.g., hanging drop suspension culture, high density culture, spinner flask culture, microcarrier culture, etc.), and contacting the cells with a first and second culture medium. Also provided are methods of treating an individual, which include producing a population of iHeps from a population of ASCs, and administering an effective number of iHeps into the individual. Kits for practicing the methods are also described herein.
FILED Wednesday, September 17, 2014
APPL NO 14/917558
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/407 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/067 (20130101)
C12N 5/0696 (20130101)
C12N 2500/62 (20130101)
C12N 2501/12 (20130101)
C12N 2501/16 (20130101)
C12N 2501/39 (20130101)
C12N 2501/119 (20130101)
C12N 2501/155 (20130101)
C12N 2501/237 (20130101)
C12N 2501/415 (20130101)
C12N 2501/602 (20130101)
C12N 2501/603 (20130101)
C12N 2501/604 (20130101)
C12N 2501/606 (20130101)
C12N 2506/45 (20130101)
C12N 2506/1384 (20130101)
C12N 2510/00 (20130101)
C12N 2513/00 (20130101)
C12N 2533/90 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004798 Bottje et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas);  THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Walter Bottje (Fayetteville, Arkansas);  Billy Hargis (Fayetteville, Arkansas);  Luc Berghman (College Station, Texas);  Young Min Kwon (West Fork, Arkansas);  Kimberly Cole (Raymond, Ohio);  Mandy Cox (Fayetteville, Arkansas);  Sherryll Layton (Rogers, Arkansas)
ABSTRACT Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.
FILED Wednesday, December 16, 2015
APPL NO 14/971704
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/74 (20130101)
A61K 39/00 (20130101)
A61K 39/12 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 39/0275 (20130101)
A61K 2035/11 (20130101)
A61K 2039/522 (20130101)
A61K 2039/523 (20130101)
A61K 2039/552 (20130101)
A61K 2039/6006 (20130101)
A61K 2039/6031 (20130101)
A61K 2039/55516 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/102 (20130101)
C12N 2760/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004800 Haynes et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Duke University (Durham, North Carolina);  Los Alamos National Security, LLC (Los Alamos, New Mexico);  The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania);  Trustees of Boston University (Boston, Massachusetts);  The United States of America as Represented by The Secretary of the Department of Health and Human Services (Washington, District of Columbia);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) Duke University (Durham, North Carolina);  Los Alamos National Security, LLC (Los Alamos, New Mexico);  The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania);  Trustees of Boston University (Boston, Massachusetts);  The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer (Washington, District of Columbia);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Barton F. Haynes (Durham, North Carolina);  Hua-Xin Liao (Durham, North Carolina);  Rebecca M. Lynch (Rockville, Maryland);  Tongqing Zhou (Rockville, Maryland);  Feng Gao (Durham, North Carolina);  Scott Boyd (Palo Alto, California);  George M. Shaw (Philadelphia, Pennsylvania);  Beatrice H. Hahn (Philadelphia, Pennsylvania);  Thomas B. Kepler (Boston, Massachusetts);  Bette T. Korber (Los Alamos, New Mexico);  Peter Kwong (Rockville, Maryland);  John Mascola (Rockville, Maryland)
ABSTRACT The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).
FILED Thursday, September 12, 2013
APPL NO 14/427581
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/21 (20130101) Original (OR) Class
A61K 2039/57 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/15022 (20130101)
C12N 2740/16022 (20130101)
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004809 Dhar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation Inc. (Athens, Georgia)
INVENTOR(S) Shanta Dhar (Athens, Georgia);  Rakesh Pathak (Athens, Georgia)
ABSTRACT Described is a targeted molecular scaffold for construction of a metabolic inhibitor loaded with cancer-cell specific activity and anti-tumor immunity. Incorporation of a mitochondria targeting moiety such as triphenylphosphonium cation through a biodegradable linker in allowed for mitochondria targeting of certain metabolic inhibitors like dichloroacetic acid (DCA).
FILED Tuesday, July 01, 2014
APPL NO 14/902514
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5146 (20130101)
A61K 9/5184 (20130101)
A61K 31/663 (20130101)
A61K 31/663 (20130101)
A61K 31/675 (20130101)
A61K 31/675 (20130101)
A61K 45/06 (20130101)
A61K 47/54 (20170801)
A61K 47/482 (20130101)
A61K 47/593 (20170801)
A61K 47/48023 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/5442 (20130101)
C07F 9/65181 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004811 Crystal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Ronald G. Crystal (New York, New York);  Jonathan B. Rosenberg (Cranbury, New Jersey);  Bishnu P. De (New Hyde Park, New York);  Martin J. Hicks (New York, New York);  Stephen M. Kaminsky (Bronx, New York)
ABSTRACT The invention is directed to a conjugate which comprises an isolated adenovirus hexon protein coupled to nicotine or a nicotine analog, as well as a method of inducing an immune response against nicotine in a human by using the conjugate.
FILED Thursday, March 14, 2013
APPL NO 14/511790
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/646 (20170801)
A61K 47/4833 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004826 Bhatia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Sangeeta N. Bhatia (Lexington, Massachusetts);  Alice A. Chen (Boston, Massachusetts);  Shengyong Ng (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Sangeeta N. Bhatia (Lexington, Massachusetts);  Alice A. Chen (Boston, Massachusetts);  Shengyong Ng (Cambridge, Massachusetts)
ABSTRACT Engineered human tissue constructs are provided that are suitable for use in making humanized animals for use in pharmaceutical development. Humanized animals having the constructs implanted in vivo are provided. Methods of making and using the tissue-engineered constructs and humanized animals are also provided.
FILED Thursday, October 06, 2011
APPL NO 13/267866
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0271 (20130101)
A01K 2207/15 (20130101)
A01K 2267/035 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/362 (20130101)
A61L 27/3604 (20130101) Original (OR) Class
A61L 27/3804 (20130101)
A61L 27/3886 (20130101)

Compositions of Macromolecular Compounds
C08L 71/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0062 (20130101)
C12N 5/0671 (20130101)
C12N 2502/13 (20130101)
C12N 2533/30 (20130101)
C12N 2533/50 (20130101)
C12N 2533/74 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5088 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004827 Badylak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher (, None)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Stephen F. Badylak (Pittsburgh, Pennsylvania);  Donald Freytes (Pittsburgh, Pennsylvania)
ABSTRACT Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
FILED Tuesday, February 18, 2014
APPL NO 14/182791
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 38/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/34 (20130101)
A61L 27/38 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/3633 (20130101) Original (OR) Class
A61L 27/3687 (20130101)
A61L 2300/64 (20130101)
A61L 2400/06 (20130101)
A61L 2420/04 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004841 Larson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Michael C. Larson (Wauwatosa, Wisconsin);  Bonnie P. Freudinger (Milwaukee, Wisconsin)
ASSIGNEE(S)
INVENTOR(S) Michael C. Larson (Wauwatosa, Wisconsin);  Bonnie P. Freudinger (Milwaukee, Wisconsin)
ABSTRACT Embodiments of the invention provide a gravity-fed blood purifier device for removing waste particles from blood. In one embodiment, the blood purifier device includes a pair of end plates and a first cylindrical tube located between the end plates. The blood purifier device also includes a porous tube contained within the space defined by the first cylindrical tube. An inlet provides unpurified red blood cells into blood purifier device. An electrode generates a negative potential across the porous tube to repel red blood cells so that the waste particles pass through the porous tube and the red blood cells do not. An outlet can be coupled to one of the end plates to receive the purified red blood cells.
FILED Tuesday, December 09, 2014
APPL NO 14/565033
ART UNIT 1754 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/36 (20130101) Original (OR) Class
A61M 2205/054 (20130101)

Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields
B03C 5/026 (20130101)
B03C 2201/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005248 Khine et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michelle Khine (Irvine, California);  Jolie McLane (Newport Beach, California);  Nicole Mendoza (Newport Beach, California)
ABSTRACT This disclosure provides a monolithic mold including a plurality of lens forming features that can be used to simultaneously form a plurality of lenses with different sizes and shapes. The mold can be formed by disposing a polymeric material around a plurality of physical objects with different shapes and sized. A method of forming the mold includes providing a substrate that has a surface with regions of low and high wettability. Water is deposited on the surface such that water droplets are formed with different contact angles. The mold is formed around the droplets.
FILED Friday, September 19, 2014
APPL NO 14/491800
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0048 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2023/38 (20130101)
B29K 2105/0085 (20130101)
B29K 2883/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005720 Sexton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) NORTH CAROLINA CENTRAL UNIVERSITY (Durham, North Carolina);  The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) North Carolina Central University (Durham, North Carolina);  The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Jonathan Z. Sexton (Raleigh, North Carolina);  Jay E. Brenman (Chapel Hill, North Carolina);  David L. Musso (Raleigh, North Carolina)
ABSTRACT The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.
FILED Friday, April 04, 2014
APPL NO 14/782415
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)
A61K 31/44 (20130101)
A61K 31/167 (20130101)
A61K 31/196 (20130101)
A61K 31/245 (20130101)
A61K 31/277 (20130101)
A61K 31/5375 (20130101)
A61K 45/06 (20130101)

Acyclic or Carbocyclic Compounds
C07C 45/46 (20130101)
C07C 67/39 (20130101)
C07C 231/02 (20130101)
C07C 233/66 (20130101)
C07C 233/81 (20130101)
C07C 235/64 (20130101) Original (OR) Class
C07C 235/68 (20130101)
C07C 253/30 (20130101)
C07C 255/60 (20130101)
C07C 2601/14 (20170501)

Heterocyclic Compounds
C07D 207/34 (20130101)
C07D 213/75 (20130101)
C07D 213/82 (20130101)
C07D 249/08 (20130101)
C07D 257/04 (20130101)
C07D 271/06 (20130101)
C07D 295/155 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005728 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Taekyu Lee (Brentwood, Tennessee);  Kwangho Kim (Nashville, Tennessee);  Plamen P. Christov (Nashville, Tennessee);  Johannes Belmar (Nashville, Tennessee);  Jason P. Burke (Houston, Texas);  Edward T. Olejniczak (Nashville, Tennessee);  Stephen W. Fesik (Nashville, Tennessee)
ABSTRACT The present application, among other things, provides compounds that are capable of inhibiting the activity of anti-apoptotic Bcl-2 family proteins, for example, myeloid cell leukemia-1 (Mcl-1) protein. The present invention also provides pharmaceutical compositions as well as methods for using provided compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein. In some embodiments, a provided compound has the structure of formula I. In some embodiments, a provided compound has the structure of formula II.
FILED Thursday, August 28, 2014
APPL NO 14/914307
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/404 (20130101)
A61K 31/422 (20130101)
A61K 31/4045 (20130101)
A61K 31/4155 (20130101)
A61K 31/4439 (20130101)
A61K 31/5377 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 209/24 (20130101)
C07D 209/26 (20130101) Original (OR) Class
C07D 401/04 (20130101)
C07D 401/14 (20130101)
C07D 403/04 (20130101)
C07D 413/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005732 Landry et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Donald W. Landry (New York, New York);  Yuli Xie (New York, New York);  Yidong Liu (New York, New York);  Gangli Gong (Little Neck, New York);  Shi-Xian Deng (White Plains, New York);  Kirsten Alison Rinderspacher (Bronx, New York)
ABSTRACT The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
FILED Monday, November 02, 2015
APPL NO 14/930409
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 211/62 (20130101)
C07D 211/96 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 409/12 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/591 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/99 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005735 Deshaies et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Raymond J. Deshaies (Pasadena, California);  Jing Li (Arcadia, California);  Seth Cohen (San Marcos, California);  Christian Perez (La Jolla, California);  Yuyong Ma (San Diego, California)
ABSTRACT Candidate compounds for specific inhibition of Rpn11 are represented by Formula 1a
where each of R2, R3, R4, R5, R6, and R7 is independently selected from hydrogen (H), substituted and unsubstituted alkyl groups, carboxyl groups, or substituted and unsubstituted carboxyamides.
FILED Wednesday, August 17, 2016
APPL NO 15/239795
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 215/54 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 405/12 (20130101)
C07D 409/12 (20130101)
C07D 413/12 (20130101)
C07D 417/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005741 Wagner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Carl Wagner (Glendale, Arizona);  Pamela Marshall (Peoria, Arizona);  Peter Jurutka (Scottsdale, Arizona)
ABSTRACT The invention provides compounds and compositions that are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, and psychotic disorders such as schizophrenia.
FILED Wednesday, January 17, 2018
APPL NO 15/873704
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/505 (20130101)

Acyclic or Carbocyclic Compounds
C07C 57/50 (20130101)
C07C 223/06 (20130101)
C07C 309/31 (20130101)
C07C 2602/10 (20170501)

Heterocyclic Compounds
C07D 209/08 (20130101)
C07D 213/48 (20130101)
C07D 213/74 (20130101)
C07D 213/79 (20130101)
C07D 215/227 (20130101)
C07D 235/10 (20130101)
C07D 239/42 (20130101)
C07D 241/20 (20130101)
C07D 241/28 (20130101)
C07D 249/18 (20130101) Original (OR) Class
C07D 307/79 (20130101)
C07D 333/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005793 Mazitschek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Ralph Mazitschek (Belmont, Massachusetts);  Alexandra M. Courtis (Davis, California);  James Adam Hendricks (Watertown, Massachusetts)
ABSTRACT This invention relates to water-soluble mono-alkoxy and mono-alkyne BODIPY derivatives, including methods for making the same. For examples, provided herein are compounds of Formula (I): (I) or a pharmaceutically acceptable salt thereof, wherein: (a) is a BODIPY ligand system; X is a halogen; L is absent or a linker; and Z is selected from the group consisting of: a group reactive with a biologically active molecule and a detectable agent.
FILED Tuesday, October 01, 2013
APPL NO 14/432567
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/0446 (20130101)

Heterocyclic Compounds
C07D 257/08 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/02 (20130101) Original (OR) Class
C07F 5/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/534 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005801 Xian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Washington State University (Pullman, Washington);  The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S) Washington State University (Pullman, Washington);  The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) Ming Xian (Pullman, Washington);  Jianming Kang (Pullman, Washington);  David J. Lefer (Saint Bernard, Louisiana)
ABSTRACT The embodiments herein generally relates to compounds and methods for releasing H2S in a pH dependent manner. In particular, the invention provides compounds of various formulations which release H2S in a controlled, predictable and sustained manner upon contact with an aqueous environment, such as the circulatory system of an animal, and which are thus suitable for in vivo delivery of H2S.
FILED Thursday, March 02, 2017
APPL NO 15/447797
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/4419 (20130101) Original (OR) Class
C07F 9/5721 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005818 Krishna et al.
FUNDED BY
Department of Commerce (DOC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) REALTA HOLDINGS, LLC (Norfolk, Virginia)
ASSIGNEE(S) REALTA HOLDINGS, LLC (Norfolk, Virginia)
INVENTOR(S) Neel K. Krishna (Norfolk, Virginia);  Kenji Cunnion (Norfolk, Virginia)
ABSTRACT The present invention provides synthetic peptide compounds and uses thereof for therapy and diagnostics of complement-mediated diseases, such as inflammatory diseases, autoimmune diseases, and microbial and bacterial infections; and non-complement-mediated diseases, such cystic fibrosis and various acute diseases. The invention is directed to modifications of a synthetic peptide of 15 amino acids from the Polar Assortant (PA) peptide, which is a scrambled peptide derived from human Astrovirus protein. In some embodiments, the invention is directed to peptide compounds that are peptide mimetics, peptide analogs and/or synthetic derivatives of PA (e.g., sarcosine derivatives) having, for example, internal peptide substitutions, and modifications, including PEGylation at the N-terminus and C-terminus. The invention further provides methods of selecting at least one synthetic peptide for treating various conditions.
FILED Friday, June 24, 2016
APPL NO 15/192934
ART UNIT 1675 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/02 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/03 (20130101)
A61K 38/162 (20130101)
A61K 38/1725 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/16611 (20130101)
C12N 2770/12022 (20130101)
C12N 2770/12033 (20130101)
C12N 2770/12071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005819 Rao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Catholic University of America (Washington, District of Columbia)
ASSIGNEE(S) The Catholic University of America (Washington, District of Columbia)
INVENTOR(S) Venigalla B. Rao (Silver Spring, Maryland);  Wadad Alsalmi (Washington, District of Columbia)
ABSTRACT An approach of producing recombinant trimers that mimic native HIV-1 envelope trimers is developed. A recombinant protein forming the recombinant trimers encompasses a recombinant HIV-1 gp140 fused to a tag through a linker at C-terminus of the recombinant HIV-1 gp140. The linker is sufficiently long so that the tag is accessible for binding by a binding molecule bound on a solid matrix. After expressed in a cell, the recombinant protein is secreted into the culture medium and assembles into recombinant trimers therein. The recombinant trimers may be directly purified from the culture medium. Cleaved and uncleaved trimers from different clade viruses are produced.
FILED Monday, November 20, 2017
APPL NO 15/817761
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/7023 (20130101)
A61K 39/00 (20130101)
A61K 39/12 (20130101)
A61K 39/21 (20130101)
A61K 2039/54 (20130101)
A61K 2039/627 (20130101)

Peptides
C07K 1/22 (20130101)
C07K 1/36 (20130101)
C07K 14/005 (20130101) Original (OR) Class
C07K 14/162 (20130101)
C07K 2319/00 (20130101)
C07K 2319/20 (20130101)
C07K 2319/21 (20130101)
C07K 2319/22 (20130101)
C07K 2319/40 (20130101)
C07K 2319/50 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/16022 (20130101)
C12N 2740/16043 (20130101)
C12N 2740/16051 (20130101)
C12N 2740/16111 (20130101)
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
C12N 2740/16234 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005821 Das Gupta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Tapas Das Gupta (River Forest, Illinois);  Ananda Chakrabarty (Villa Park, Illinois)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Tapas Das Gupta (River Forest, Illinois);  Ananda Chakrabarty (Villa Park, Illinois)
ABSTRACT The present invention provides modified cupredoxin derived peptides with pharmacologic activity that have improved pharmacokinetic properties, and methods to use them to treat mammals suffering from various conditions related to the pharmacologic activities. Modifications of the cupredoxin derived peptides include amino acid sequence variants and structural derivations that increase the plasma half-life of the peptide, increase the specific activity of the pharmacologic activity, decrease immunogenicity, and decrease the biotransformation of the peptides. The modified cupredoxin derived peptides can be used in methods to treat mammals for cancer, conditions related to inappropriate angiogenesis, viral and bacterial infections, and specifically HIV and malaria, conditions related to ephrin signaling, and to deliver cargo compounds, including diagnostic compounds, to cancer cells.
FILED Tuesday, September 11, 2007
APPL NO 11/853497
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/04 (20130101)
A61K 38/08 (20130101)
A61K 38/10 (20130101)
A61K 38/164 (20130101)

Peptides
C07K 7/00 (20130101)
C07K 14/21 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005822 Simon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
ASSIGNEE(S) MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
INVENTOR(S) Roger P. Simon (Atlanta, Georgia);  Zhi-Gang Xiong (Atlanta, Georgia)
ABSTRACT A system, including methods and compositions, for treatment of ischemia.
FILED Friday, May 27, 2016
APPL NO 15/167702
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/439 (20130101)
A61K 31/498 (20130101)
A61K 31/4418 (20130101)
A61K 31/4965 (20130101)
A61K 38/16 (20130101)
A61K 38/17 (20130101)
A61K 38/1767 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/43518 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005825 Agadjanyan et al.
FUNDED BY
Department of Energy (DOE)
Institute for Molecular Medicine (IMMED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) INSTITUTE FOR MOLECULAR MEDCINE, INC. (Huntington Beach, California)
ASSIGNEE(S) INSTITUTE FOR MOLECULAR MEDICINE, INC. (Huntington Beach, California)
INVENTOR(S) Michael G. Agadjanyan (Huntington Beach, California);  Anahit Ghochikyan (Huntington Beach, California)
ABSTRACT Disclosed are compositions, comprising one or more immunogens, wherein each immunogen comprises at least two regions, wherein one region comprises at least one amyloid-β (Aβ) B cell epitope or at least one Tau B cell epitope or at least one α-synuclein B cell epitope or combinations thereof, and a second region comprises at least one foreign T helper cell (Th) epitope, and usually multiple foreign Th epitopes. Methods of making and using the compositions are also disclosed.
FILED Friday, February 20, 2015
APPL NO 14/628023
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/0007 (20130101)
A61K 2039/53 (20130101)
A61K 2039/57 (20130101)
A61K 2039/70 (20130101)
A61K 2039/575 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 14/47 (20130101)
C07K 14/4711 (20130101) Original (OR) Class
C07K 2319/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005833 Bose et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Washington State University (Pullman, Washington);  The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) WASHINGTON STATE UNIVERSITY (Pullman, Washington);  THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Santanu Bose (Pullman, Washington);  Philippe Tessier (Quebec, Canada)
ABSTRACT The present disclosure provides methods of treating a pathogen-induced lung inflammation in a subject are provided in which an anti-S100A9 antibody is administered to a subject. Methods of treating a respiratory virus infection by administering an anti-S100A9 antibody are also provided.
FILED Thursday, December 31, 2015
APPL NO 14/985591
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/24 (20130101) Original (OR) Class
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006004 Furcht et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Leo T. Furcht (Golden Valley, Minnesota);  Catherine M. Verfaillie (Leuven, Belgium);  Morayma Reyes (Sammamish, Washington)
ASSIGNEE(S) ABT Holding Company (Cleveland, Ohio)
INVENTOR(S) Leo T. Furcht (Golden Valley, Minnesota);  Catherine M. Verfaillie (Leuven, Belgium);  Morayma Reyes (Sammamish, Washington)
ABSTRACT The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic uses for the isolated cells.
FILED Wednesday, April 01, 2009
APPL NO 12/416715
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)
A61K 2035/124 (20130101)
A61K 2039/5156 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0607 (20130101) Original (OR) Class
C12N 2501/11 (20130101)
C12N 2501/105 (20130101)
C12N 2501/135 (20130101)
C12N 2501/235 (20130101)
C12N 2503/00 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006023 Chinnaiyan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Arul M. Chinnaiyan (Plymouth, Michigan);  Xiaoju Wang (Ann Arbor, Michigan)
ABSTRACT The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods and compositions for phage microarray profiling of cancer (e.g., prostate, lung, or breast cancer). The present invention further provides novel markers useful for the diagnosis, characterization, and treatment of cancers.
FILED Tuesday, January 12, 2016
APPL NO 14/993792
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/4748 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1037 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/136 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6845 (20130101)
G01N 33/57415 (20130101)
G01N 33/57423 (20130101)
G01N 33/57434 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006027 Bennett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Ionis Pharmaceuticals, Inc. (Carlsbad, California);  University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) Ionis Pharmaceuticals, Inc. (Carlsbad, California);  University of Utah Reseach Foundation (Salt Lake City, Utah)
INVENTOR(S) C. Frank Bennett (Carlsbad, California);  Susan M. Freier (San Diego, California);  Stefan M. Pulst (Salt Lake City, Utah);  Daniel R. Scoles (Salt Lake City, Utah);  Gene Hung (San Diego, California)
ABSTRACT Disclosed herein are methods for decreasing Ataxin 2 mRNA and protein expression. Such methods are useful to treat, prevent, or ameliorate Ataxin 2 associated diseases, disorders, and conditions. Such Ataxin 2 associated diseases include spinocerebellar ataxia type 2 (SCA2), amyotrophic lateral sclerosis (ALS), and parkinsonism. Provided are methods for reducing expression of Ataxin 2 (ATXN2) mRNA and protein in an animal. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases, including spinocerebellar ataxia type 2 (SCA2), amyotrophic lateral sclerosis (ALS), and parkinsonism by inhibiting expression of Ataxin 2 in an animal.
FILED Thursday, March 19, 2015
APPL NO 15/127352
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/141 (20130101)
C12N 2310/315 (20130101)
C12N 2310/317 (20130101)
C12N 2310/321 (20130101)
C12N 2310/323 (20130101)
C12N 2310/341 (20130101)
C12N 2310/346 (20130101)
C12N 2310/3231 (20130101)
C12N 2310/3341 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006028 Harper et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Scott Harper (Iowa City, Iowa);  Beverly L. Davidson (Iowa City, Iowa)
ABSTRACT The present invention is directed to nucleic acid molecules containing a loop sequence designed to circumvent exportin-5 mediated export, and methods using these novel molecules.
FILED Thursday, May 26, 2016
APPL NO 15/165898
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/53 (20130101)
C12N 2310/111 (20130101)
C12N 2310/141 (20130101)
C12N 2310/531 (20130101)
C12N 2320/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006047 Kay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Mark A. Kay (Los Altos, California);  Jiamiao Lu (Mountain View, California)
ABSTRACT Provided are nucleic acids and expression vectors having a non-silencing selectable marker gene, and methods of using the same. A subject expression vector includes an expression cassette and a non-silencing selectable marker gene. In some cases, the non-silencing selectable marker gene provides for drug resistance for prokaryotic cells, and includes a nucleotide sequence that (i) encodes a drug selectable marker protein; (ii) is operably linked to a promoter functional in prokaryotic cells, and (iii) includes an increased A/T content relative to a corresponding wild type nucleotide sequence. In some cases, the non-silencing selectable marker gene provides for drug resistance for prokaryotic cells, and includes a nucleotide sequence that (i) encodes a drug selectable marker protein; (ii) is operably linked to a promoter functional in prokaryotic cells, and (iii) has an A/T content in a range of from 52% to 70%.
FILED Tuesday, February 09, 2016
APPL NO 15/019838
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)

Peptides
C07K 14/245 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/86 (20130101)
C12N 9/1205 (20130101)
C12N 15/85 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006053 Baltimore et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) David Baltimore (Pasadena, California);  Matthew Porteus (Pasadena, California)
ABSTRACT Gene targeting is a technique to introduce genetic change into one or more specific locations in the genome of a cell. For example, gene targeting can introduce genetic change by modifying, repairing, attenuating or inactivating a target gene or other chromosomal DNA. In one aspect, this disclosure relates to methods and compositions for gene targeting with high efficiency in a cell. This disclosure also relates to methods of treating or preventing a genetic disease in an individual in need thereof. Further disclosed are chimeric nucleases and vectors encoding chimeric nucleases.
FILED Thursday, September 08, 2016
APPL NO 15/259848
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/907 (20130101) Original (OR) Class
C12N 2800/80 (20130101)
C12N 2830/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006082 Samusik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Nikolay Samusik (Mountain View, California);  Garry P. Nolan (Redwood City, California);  Yury Goltsev (Stanford, California)
ABSTRACT A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the oligonucleotide, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
FILED Tuesday, December 05, 2017
APPL NO 15/832627
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6818 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006089 Wei
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wenyi Wei (Brookline, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Wenyi Wei (Brookline, Massachusetts)
ABSTRACT Some embodiments are based on the discovery that proliferative diseases (e.g., neoplastic diseases, for example, tumors or cancers) having an FBW7 mutation or other FBW7 deficiency are sensitive to Mcl1 inhibiting agents, but resistant to pro-apoptotic drugs that do not inhibit Mcl1. Some embodiments provide methods of treating a proliferative disease based on an assessment of FBW7 expression level or mutation status. Some embodiments provide methods of classifying a hyperproliferative cell or cell population, for example, a malignant cell or cell population based on an assessment of FBW7 expression level or mutation status. Some embodiments provide methods of selecting a treatment regimen for treating a proliferative disease, for example, a malignant disorder, based on an assessment of FBW7 expression level or mutation status.
FILED Friday, March 02, 2012
APPL NO 14/001970
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/44 (20130101)
A61K 31/495 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006097 Shu et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America as represented by the Secretary of the Dept. of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretry, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Bo Shu (Lilburn, Georgia);  Stephen Lindstrom (Atlanta, Georgia);  Kai-Hui Wu (Atlanta, Georgia);  LaShondra Berman (Decatur, Georgia);  Shannon L. Emery (Atlanta, Georgia);  Christine Warnes (Alpharetta, Georgia);  Catharine McCord (Denver, Colorado)
ABSTRACT Compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample, are provided. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also provided.
FILED Wednesday, October 22, 2014
APPL NO 15/030843
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/701 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006896 Fernstrom et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) John Fernstrom (Pittsburgh, Pennsylvania);  Madelyn Fernstrom (Pittsburgh, Pennsylvania);  Wenyan Jia (Wexford, Pennsylvania);  Robert Sclabassi (Gibsonia, Pennsylvania);  Mingui Sun (Pittsburgh, Pennsylvania)
ABSTRACT Electronic systems, devices and methods are provided to accurately record and analyze food intake and physical activity in a subject. A device is provided to be placed on a subject which records video using at least two video cameras positioned to record stereoscopic image pair, as well as other physiological and/or environmental data including, for example, oxygen saturation, heart rate, and environmental factors such as physical location, temperature, and humidity. Video data is analyzed along with other data obtained by the device to determine food consumption and/or physical activity of the subject, much of which is accomplished by automated computer-implemented processes.
FILED Wednesday, November 14, 2012
APPL NO 13/676468
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/04 (20130101)
A61B 5/0022 (20130101)
A61B 5/0024 (20130101)
A61B 5/0077 (20130101)
A61B 5/1112 (20130101)
A61B 5/1118 (20130101)
A61B 5/02055 (20130101)
A61B 5/6802 (20130101)
A61B 5/6805 (20130101)
A61B 5/6816 (20130101)
A61B 5/14551 (20130101)
A61B 7/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/00 (20130101)
G01N 33/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006900 Sniadecki et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Nathan J. Sniadecki (Seattle, Washington);  Lucas Ting (Seattle, Washington)
ABSTRACT The present technology relates generally to devices to expose cells to fluid shear forces and associated systems and methods. In particular, several embodiments are directed toward devices to expose cells to fluid shear forces in order to measure changes in internal cell forces. In some embodiments, a fluidic device includes a flow unit configured to induce fluid flow through the device. The device further includes a fluid channel configured to accept a biological sample dispersed on an array of flexible structures. The flow unit can be configured to induce disturbed and/or laminar flow in the fluid channel. The device can further include optical or magnetic detection means configured to measure a degree of deflection of one or more flexible structures in the array.
FILED Friday, August 21, 2015
APPL NO 14/832164
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502746 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/20 (20130101)
C12M 23/26 (20130101)
C12M 29/00 (20130101)
C12M 35/04 (20130101)
C12M 41/46 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1056 (20130101)
G01N 15/1404 (20130101)
G01N 15/1459 (20130101)
G01N 15/1463 (20130101)
G01N 33/4905 (20130101) Original (OR) Class
G01N 33/5302 (20130101)
G01N 2015/1006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006912 Dattwyler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BIOPEPTIDES CORP. (East Setauket, New York)
ASSIGNEE(S) Biopeptides LLC (Setauket, New York)
INVENTOR(S) Raymond J. Dattwyler (East Setauket, New York);  Paul M. Arnaboldi (Queens, New York)
ABSTRACT The present invention relates, e.g., to a composition comprising peptides represented by SEQ ID NO:1, or active variants thereof, wherein the peptides or active variants can bind specifically to an antibody induced by a causative agent of Lyme disease (a pathogenic Borrelia), e.g. in a sample from a subject having Lyme disease. Compositions of the invention may comprise multiple peptides, from multiple proteins. Diagnostic kits comprising the peptides are described, as are diagnostic assays using the peptides.
FILED Monday, December 08, 2014
APPL NO 15/102002
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/20 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56911 (20130101) Original (OR) Class
G01N 2333/20 (20130101)
G01N 2469/20 (20130101)
G01N 2800/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006913 Zlotnick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Ndianapolis, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) Adam Zlotnick (Bloomington, Indiana);  Lichun Li (Bloomington, Indiana);  Michael S. Van Nieuwenhze (Bloomington, Indiana);  William W. Turner (Bloomington, Indiana)
ABSTRACT Heteroaryldihydropyrimidine (HAP)-based fluorescent stains (compounds), as well as uses of such stains as diagnostic reagents, viral-tracking agents, and/or tools for drug discovery are described. The present invention relates to heteroaryldihydropyrimidine (HAP)-based fluorescent stains (compounds), as well as uses of such stains as diagnostic reagents, viral-tracking agents, and/or tools for drug discovery.
FILED Thursday, March 20, 2014
APPL NO 14/777636
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0017 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 11/08 (20130101)
C09B 11/24 (20130101)
C09B 23/02 (20130101)
C09B 57/00 (20130101)
C09B 57/02 (20130101)
C09B 57/10 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101) Original (OR) Class
G01N 2333/02 (20130101)
G01N 2500/02 (20130101)
G01N 2500/04 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006916 Kwong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Gabriel A. Kwong (Boston, Massachusetts);  Sangeeta N. Bhatia (Lexington, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Gabriel A. Kwong (Boston, Massachusetts);  Sangeeta N. Bhatia (Lexington, Massachusetts)
ABSTRACT Some aspects of this invention provide reagents and methods for the sensitive, quantitative and simultaneous detection of target analytes in complex biological samples by liquid chromatography tandem mass spectrometry (LC MS/MS). Some aspects of this invention provide affinity reagents encoded with mass reporters for the sensitive and quantitative translation of an analyte of interest into a mass tag. The reagents and methods provided herein have general utility in analyte detection and encoding, for example, in biomolecular profiling, molecular diagnostics, and biochemical encoding.
FILED Thursday, March 15, 2012
APPL NO 14/005416
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 14/001 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/58 (20130101) Original (OR) Class
G01N 33/6848 (20130101)
G01N 2458/15 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006922 Dasari et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ramachandra Dasari (Shererville, Indiana);  Ishan Barman (Boston, Massachusetts);  Narahara Chari Dingari (Somerville, Massachusetts);  Jeon Woong Kang (Melrose, Massachusetts)
ABSTRACT The present invention relates to the optical measurement of blood analytes, such as glycated hemoglobin (HbA1c) and serum albumin as a functional metric of mean blood glucose in the diagnosis of diabetic patients. Non-enhanced Raman spectroscopy is employed as the analytical method for quantitative detection of blood analytes. Using processing techniques, non-enzymatic glycosylation (glycation) of the analytes results in measurable and highly reproducible changes in the acquired spectral data, which enable the accurate measurements and classification of glycated and unglycated analytes.
FILED Friday, December 21, 2012
APPL NO 14/367633
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/65 (20130101)
G01N 33/49 (20130101)
G01N 33/723 (20130101) Original (OR) Class
G01N 33/726 (20130101)
G01N 2440/38 (20130101)
G01N 2800/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007920 Ranieri et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Nicola Ranieri (Mainville, Ohio);  Mark R. Witkowski (West Chester, Ohio);  Mike D. Green (Atlanta, Georgia)
ABSTRACT One aspect of the invention provides a device for detecting a counterfeit product. The device includes: a plurality of light sources configured to emit light at a plurality of different wavelengths onto an object potentially including a suspect product; at least one image acquisition device adapted and configured to acquire image data; and a communications interface adapted and configured to transmit the image data to a computing device selected from the group consisting of: a tablet computer and a smartphone.
FILED Friday, December 06, 2013
APPL NO 14/650244
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/9508 (20130101)
G01N 33/15 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/2018 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 30/0185 (20130101) Original (OR) Class
G06Q 50/22 (20130101)

Pictorial Communication, e.g Television
H04N 5/2256 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007961 Grudzinski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Joseph J. Grudzinski (Madison, Wisconsin);  Robert Jeraj (Madison, Wisconsin);  Wolfgang A. Tome (Madison, Wisconsin);  Jamey P. Weichert (Fitchburg, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Joseph J. Grudzinski (Madison, Wisconsin);  Robert Jeraj (Madison, Wisconsin);  Wolfgang A. Tome (Madison, Wisconsin);  Jamey P. Weichert (Fitchburg, Wisconsin)
ABSTRACT A treatment schedule for radiopharmaceuticals is developed by collecting a volumetric history of tissue uptake in identified volumes of interest using emitted-radiation scans and relating this data to a treatment-radiopharmaceutical to develop a quantitatively accurate radiation treatment schedule of delivery amounts and delivery times of the treatment-radiopharmaceutical. This data may also be used to model biological effective dose and to prepare augmenting external radiation beam treatment schedules.
FILED Wednesday, September 09, 2009
APPL NO 12/556323
ART UNIT 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Electric Digital Data Processing
G06F 19/00 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007982 Heine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida);  MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
ASSIGNEE(S) H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida);  Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) John J. Heine (New Port Richey, Florida);  Thomas A. Sellers (Tampa, Florida);  Celine M. Vachon (Rochester, Minnesota);  Erin E. Fowler (Tampa, Florida)
ABSTRACT An automated percentage of breast density measure (PDa) that analyzes signal dependent noise (SDN) based on a wavelet expansion using full field digital mammography (FFDM). A matched case-control dataset is used with images acquired from a specific direct x-ray capture FFDM system. PDa is applied to the raw and clinical display representation images. Transforming (pixel mapping) of the raw image to another representation (raw-transformed) is performed using differential evolution optimization and investigated the influence of lowering the native spatial resolution of the image by a one-half. When controlling for body mass index, the quartile specific ORs for the associations of PDa with breast cancer varied with representation and resolution. PDa is a valid automated breast density measurement for a specific FFDM technology and compares well against PD (operator-assisted or the standard) when applied to either the raw-transformed or clinical display images from this FFDM technology.
FILED Friday, May 30, 2014
APPL NO 14/893603
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/502 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0051 (20130101)
G06K 9/527 (20130101)
G06K 9/623 (20130101)
G06K 2209/05 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/41 (20170101)
G06T 2207/10116 (20130101)
G06T 2207/20076 (20130101)
G06T 2207/30068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008375 Ouyang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Zheng Ouyang (West Lafayette, Indiana);  Yue Ren (West Lafayette, Indiana);  Jiangjiang Liu (West Lafayette, Indiana);  Linfan Li (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems for analyzing a sample and methods of use thereof. In certain aspects, the invention provides systems that include an ionization probe and a mass analyzer. The probe includes a hollow body that has a distal tip. The probe also includes a substrate that is at least partially disposed within the body and positioned prior to the distal tip so that sample extracted from the substrate flows into the body prior to exiting the distal tip. The probe also includes an electrode that operably interacts with sample extracted from the substrate.
FILED Friday, January 10, 2014
APPL NO 14/426591
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/167 (20130101)
H01J 49/0409 (20130101) Original (OR) Class
H01J 49/0431 (20130101)
H01J 49/4205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10004809 Dhar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation Inc. (Athens, Georgia)
INVENTOR(S) Shanta Dhar (Athens, Georgia);  Rakesh Pathak (Athens, Georgia)
ABSTRACT Described is a targeted molecular scaffold for construction of a metabolic inhibitor loaded with cancer-cell specific activity and anti-tumor immunity. Incorporation of a mitochondria targeting moiety such as triphenylphosphonium cation through a biodegradable linker in allowed for mitochondria targeting of certain metabolic inhibitors like dichloroacetic acid (DCA).
FILED Tuesday, July 01, 2014
APPL NO 14/902514
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5146 (20130101)
A61K 9/5184 (20130101)
A61K 31/663 (20130101)
A61K 31/663 (20130101)
A61K 31/675 (20130101)
A61K 31/675 (20130101)
A61K 45/06 (20130101)
A61K 47/54 (20170801)
A61K 47/482 (20130101)
A61K 47/593 (20170801)
A61K 47/48023 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/5442 (20130101)
C07F 9/65181 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004884 Allan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) University of Washington (Seattle, Washington);  Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Christopher H. Allan (Seattle, Washington);  Muthu B. J. Wijesundara (Fort Worth, Texas)
ABSTRACT A protective and permissive healing medical device comprising a sealable enclosure made from a flexible and see-though dressing, coupled with a scaffold structure capable of separating portions of the inner surface of the sealable enclosure from the outer portions of an extremity sealed inside the device, a plurality of ports for delivering materials into and extracting mediums from the sealable enclosure consistent with a therapeutic environment for the injury within the device, and a plurality of digit receiving portions facilitating individually articulable movement during healing within the sealable enclosure.
FILED Wednesday, March 18, 2015
APPL NO 14/661809
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/00068 (20130101)
A61F 13/104 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/0023 (20130101)
A61M 1/0084 (20130101)
A61M 1/0088 (20130101)
A61M 35/00 (20130101) Original (OR) Class
A61M 2205/3303 (20130101)
A61M 2205/3584 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004924 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
APPLICANT(S) Paragon Space Development Corporation (Tucson, Arizona)
ASSIGNEE(S) Paragon Space Development Corporation (Tucson, Arizona)
INVENTOR(S) Grant A. Anderson (Tucson, Arizona);  Taber K. MacCallum (Tucson, Arizona);  Sebastian A. Padilla (Tucson, Arizona);  Chad E. Bower (Tucson, Arizona)
ABSTRACT A system is designed to increase diver safety in a high-risk environment containing one or more hazardous materials. The system includes chemically-hardened surface-supplied diving equipment designed to provide full environment isolation for the diver. The system also includes a dive helmet and a surface-return exhaust system, where the surface-return exhaust system includes a demand exhaust regulator that serves as a pressure-actuated valve to enable exhausting to a breathable atmosphere outside of a dive helmet instead of exhausting into the environment containing one or more hazardous materials. The system also includes retrofittable kits enabling the upgrading of contaminant-vulnerable materials of an existing dive helmet. The system also includes fluoroelastomeric materials and components to implement in a closed circuit dive system.
FILED Thursday, October 03, 2013
APPL NO 14/045685
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Devices, Apparatus or Methods for Life-saving
A62B 7/00 (20130101)
A62B 9/00 (20130101)
A62B 9/02 (20130101) Original (OR) Class
A62B 9/022 (20130101)
A62B 18/006 (20130101)
A62B 18/10 (20130101)

Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects
B63C 11/00 (20130101)
B63C 11/02 (20130101)
B63C 11/06 (20130101)
B63C 11/12 (20130101)
B63C 11/14 (20130101)
B63C 11/18 (20130101)
B63C 11/20 (20130101)
B63C 11/202 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005248 Khine et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michelle Khine (Irvine, California);  Jolie McLane (Newport Beach, California);  Nicole Mendoza (Newport Beach, California)
ABSTRACT This disclosure provides a monolithic mold including a plurality of lens forming features that can be used to simultaneously form a plurality of lenses with different sizes and shapes. The mold can be formed by disposing a polymeric material around a plurality of physical objects with different shapes and sized. A method of forming the mold includes providing a substrate that has a surface with regions of low and high wettability. Water is deposited on the surface such that water droplets are formed with different contact angles. The mold is formed around the droplets.
FILED Friday, September 19, 2014
APPL NO 14/491800
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0048 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2023/38 (20130101)
B29K 2105/0085 (20130101)
B29K 2883/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005690 Wiest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Aaron Wiest (Norco, California);  Craig Andrew MacDougall (Norco, California);  Robert Dale Conner (Oak Hills, California)
ABSTRACT Novel cellular solids and foams from amorphous materials with a glass transition temperature (Tg) and methods of forming such materials are provided. In particular, foams are formed by expanding or compressing hollow spheres made of a high strength amorphous material, which is defined as a material having high strength characteristics, but also possessing a glass transition within a confined space. Using such a method, it has been unexpectedly found that it is possible to make cellular structures, including both open and closed cell foams, with customizable properties from materials that have been inaccessible with conventional methods. Moreover, based on calculations high specific strengths and stiffnesses are expected.
FILED Thursday, July 02, 2015
APPL NO 14/790348
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 44/445 (20130101)
B29C 44/3403 (20130101)
B29C 44/3461 (20130101)
B29C 70/66 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 2266/06 (20130101)

Manufacture, Shaping, or Supplementary Processes
C03B 19/08 (20130101) Original (OR) Class
C03B 19/107 (20130101)
C03B 23/20 (20130101)

Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 11/002 (20130101)

Alloys
C22C 45/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005796 Briseno et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Alejandro L. Briseno (Amherst, Massachusetts);  Lei Zhang (Amherst, Massachusetts)
ABSTRACT We report the synthesis and characterization of novel bistetracenes, an unconventional, linearly extended conjugated core with eight fused rings. Also described are bisoligoacenes. In general, the properties and stability of large polycyclic aromatic hydrocarbons (PAHs) strongly depend on the mode of ring annellation and the topology of their it-electron systems, which are usually associated with the resonance stabilization energy in large PAHs.
FILED Friday, May 01, 2015
APPL NO 15/307968
ART UNIT 1671 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/0809 (20130101) Original (OR) Class
C07F 7/0827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006051 Boeke et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) New York University (New York, New York);  Johns Hopkins University (, None)
ASSIGNEE(S) New York University (New York, New York);  Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Jef Boeke (New York, New York);  Leslie Mitchell (New York, New York);  Yizhi Cai (Edinburgh, United Kingdom);  Neta Agmon (New York, New York)
ABSTRACT Provided are compositions and methods for use in assembling and expressing a plurality of transcription units using, in one aspect, homologous recombination in yeast. Yeast containing the plurality of transcription units, and isolated transcription units, are also provided. Kits for use in making the yeast and the transcript units are further included.
FILED Monday, April 24, 2017
APPL NO 15/495390
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/64 (20130101)
C12N 15/66 (20130101)
C12N 15/81 (20130101)
C12N 15/905 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006082 Samusik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Nikolay Samusik (Mountain View, California);  Garry P. Nolan (Redwood City, California);  Yury Goltsev (Stanford, California)
ABSTRACT A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the oligonucleotide, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
FILED Tuesday, December 05, 2017
APPL NO 15/832627
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6818 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006295 Spangler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Brandon W. Spangler (Vernon, Connecticut);  Dominic J. Mongillo (West Hartford, Connecticut)
ABSTRACT Disclosed is a gas turbine engine including a compressor section and a turbine section. The gas turbine engine includes a gas turbine engine component having a first wall providing an outer surface of the gas turbine engine component and a second wall spaced-apart from the first wall. The first wall is a gas-path wall exposed to a core flow path of the gas turbine engine. The second wall is a non-gas-path wall. A cooling passageway is provided between the second wall and the first wall. The second wall has a trip strip provided thereon.
FILED Friday, May 23, 2014
APPL NO 14/893795
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/02 (20130101)
F01D 5/188 (20130101) Original (OR) Class
F01D 5/189 (20130101)
F01D 9/041 (20130101)
F01D 25/12 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/12 (20130101)
F05D 2240/30 (20130101)
F05D 2260/202 (20130101)
F05D 2260/221 (20130101)
F05D 2260/2212 (20130101)
F05D 2260/22141 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/676 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006366 Pickford
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) Simon Pickford (South Glastonbury, Connecticut)
ABSTRACT The present disclosure provides systems and methods related to thermal management systems for gas turbine engines. For example, a thermal management system comprises a fuel circuit, comprising a burn line and a recirculation line, and a burn line fuel-oil cooler, coupled to the burn line and an oil circuit. The oil circuit comprises a sending portion, configured to carry oil from the burn line fuel-oil cooler to an engine lube system, and a returning portion, configured to carry oil from the engine lube system to the burn line fuel-oil cooler. The thermal management system further comprises a recirculation fuel-oil cooler, coupled to the recirculation line and the returning portion, and an air-fuel cooler coupled to the recirculation line.
FILED Tuesday, April 28, 2015
APPL NO 14/697880
ART UNIT 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/16 (20130101) Original (OR) Class
F02C 7/224 (20130101)
F02C 9/32 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 27/02 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006369 Kupiszewski
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) GENERAL ELECTRIC COMPANY (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Thomas Kupiszewski (Liberty Township, Ohio)
ABSTRACT A method and system for a heat exchanger are provided. The heat exchanger includes a plurality of arcuate heat exchanger segments, each including a first header configured to extend circumferentially about at least a portion of a circumference of an internal surface of a fluid duct. The heat exchanger also includes a second header configured to extend circumferentially about the portion spaced axially apart from the first header in a direction opposite of fluid flow through the fluid duct and a first plurality of heat exchanger tubes extending generally axially between the first header and the second header, the first plurality of heat exchanger tubes each including a first flow path separate from a second flow path of any other of the first plurality of heat exchanger tubes, the first flow path changing direction along the flow path from the first header to the second header.
FILED Thursday, June 18, 2015
APPL NO 14/742970
ART UNIT 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 25/12 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)
F02C 7/14 (20130101)
F02C 7/18 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/60 (20130101)
F05D 2250/71 (20130101)
F05D 2260/213 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 7/1607 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/671 (20130101)
Y02T 50/675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006444 Ting et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jason Ming Ting (Katy, Texas);  Alok Suryavamsee Tayi (Somerville, Massachusetts);  Bobak Mosadegh (New York, New York);  George M. Whitesides (Newton, Massachusetts)
ABSTRACT A soft robot device includes at least a first thermoplastic layer and a second thermoplastic layer, wherein at least one layer is comprised of an extensible thermoplastic material; at least one layer is an inextensible layer; and at least one layer comprises a pneumatic network, wherein the pneumatic network is configured to be in fluidic contact with a pressurizing source, wherein the first and second thermoplastic layers are thermally bonded to each other.
FILED Monday, April 13, 2015
APPL NO 14/685456
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 65/02 (20130101)
B29C 66/45 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/71 (20130101)
B29C 66/0342 (20130101)
B29C 66/712 (20130101)
B29C 66/1122 (20130101)
B29C 66/5346 (20130101)
B29C 66/73921 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2021/003 (20130101)
B29K 2075/00 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/26 (20130101)
B32B 5/028 (20130101)
B32B 7/02 (20130101)
B32B 27/08 (20130101)
B32B 27/40 (20130101)
B32B 37/04 (20130101)
B32B 37/18 (20130101)
B32B 2307/51 (20130101)

Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/06 (20130101) Original (OR) Class

Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for
F15B 15/103 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 156/10 (20150115)
Y10T 156/1041 (20150115)
Y10T 428/2495 (20150115)
Y10T 428/24331 (20150115)
Y10T 428/24612 (20150115)
Y10T 428/24942 (20150115)
Y10T 428/24983 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006720 Bhunia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Avijit Bhunia (Thousand Oaks, California);  Qingjun Cai (Thousand Oaks, California);  Chung-Lung Chen (Thousand Oaks, California)
ASSIGNEE(S) TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California)
INVENTOR(S) Avijit Bhunia (Thousand Oaks, California);  Qingjun Cai (Thousand Oaks, California);  Chung-Lung Chen (Thousand Oaks, California)
ABSTRACT A cooling system that includes a substrate having a metallic face, at least one microporous wick formation in thermal communication with the metallic face, and a liquid delivery head positioned in complementary opposition to the metallic face, the liquid delivery head having at least one nozzle for directing a liquid towards the metallic face.
FILED Monday, August 01, 2011
APPL NO 13/195515
ART UNIT 3744 — Material and Article Handling
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/046 (20130101) Original (OR) Class
F28D 15/0266 (20130101)
F28D 2021/0028 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/427 (20130101)
H01L 23/3675 (20130101)
H01L 23/4735 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006770 Hamilton
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John Hamilton (Solsberry, Indiana)
ABSTRACT A remote geolocation system is provided including an inertial navigation unit (INU) having orthogonally disposed three axis accelerometers/gyroscopes in a strap down configuration in a case, a laser range finder (LRF) aligned with one INU axis, a GPS, and machine instructions that create a virtual INU (VINU) used to determine orientation of the case at an activation point (AP) when the LRF is pointed at a target, take sequences of global positioning satellites (GPS) location data and inertial measuring unit (IMU) orientation measurements from a starting location to the AP, draw a line between the starting location and the AP, identify a longitude line (LL) passing through the line, align one VINU axis with the LL, align another VINU axis with INU detected gravity, and align a remaining VINU axis with the LRF's output at the AP.
FILED Monday, January 30, 2017
APPL NO 15/419392
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/165 (20130101) Original (OR) Class

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 19/14 (20130101)
G01S 19/53 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006900 Sniadecki et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Nathan J. Sniadecki (Seattle, Washington);  Lucas Ting (Seattle, Washington)
ABSTRACT The present technology relates generally to devices to expose cells to fluid shear forces and associated systems and methods. In particular, several embodiments are directed toward devices to expose cells to fluid shear forces in order to measure changes in internal cell forces. In some embodiments, a fluidic device includes a flow unit configured to induce fluid flow through the device. The device further includes a fluid channel configured to accept a biological sample dispersed on an array of flexible structures. The flow unit can be configured to induce disturbed and/or laminar flow in the fluid channel. The device can further include optical or magnetic detection means configured to measure a degree of deflection of one or more flexible structures in the array.
FILED Friday, August 21, 2015
APPL NO 14/832164
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502746 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/20 (20130101)
C12M 23/26 (20130101)
C12M 29/00 (20130101)
C12M 35/04 (20130101)
C12M 41/46 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1056 (20130101)
G01N 15/1404 (20130101)
G01N 15/1459 (20130101)
G01N 15/1463 (20130101)
G01N 33/4905 (20130101) Original (OR) Class
G01N 33/5302 (20130101)
G01N 2015/1006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006919 Woodbury et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Neal Woodbury (Tempe, Arizona);  Stephen Johnston (Tempe, Arizona);  Phillip Stafford (Phoenix, Arizona)
ABSTRACT The present application provides arrays for use in immunosignaturing and quality control of such arrays. Also disclosed are peptide arrays and uses thereof for diagnostics, therapeutics and research.
FILED Friday, March 14, 2014
APPL NO 14/773750
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6845 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007852 Chen et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Lingji Chen (Acton, Massachusetts);  Balasubramaniam Ravichandran (Winchester, Massachusetts)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Lingji Chen (Acton, Massachusetts);  Balasubramaniam Ravichandran (Winchester, Massachusetts)
ABSTRACT Solutions for object tracking problems are presented by gathering images using one or more cameras, processing the gathered images to generate a directed acyclic graph, using the directed acyclic graph to determine a path cover that achieves maximum weight and satisfies one or more positive or negative constraints, and using the path cover to solve the object tracking problem. A first set of solutions utilizes trellis graphs, a second set of solutions employs a greedy approach, and a third set of solutions uses search algorithms.
FILED Friday, May 27, 2016
APPL NO 15/166791
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00664 (20130101)
G06K 9/00771 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/246 (20170101)
G06T 2207/30241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007974 Nazemi
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Night Vision and Electronic Sensors Directorate (NVESD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Sensors Unlimited, Inc. (Princeton, New Jersey)
ASSIGNEE(S) Sensors Unlimited, Inc. (Princeton, New Jersey)
INVENTOR(S) Jonathan Nazemi (Doylestown, Pennsylvania)
ABSTRACT A method of enhancing an image includes constructing an input histogram corresponding to an input image received at a focal plane array, the input histogram representing a pixel intensity distribution corresponding to the input image and performing an analytical operation on the input histogram to produce a modified cumulative distribution, wherein the analytical operation is a function of camera temperature. The input image is transformed using the modified cumulative distribution to produce an enhanced output image corresponding to the input image, wherein at least a portion of the input image is enhanced in the output image. In addition to or in lieu of the non-linear operation, the binning edges of the input histogram can be adjusted based on at least one of camera temperature and sensitivity state to construct an adjusted cumulative distribution.
FILED Friday, June 10, 2016
APPL NO 15/178888
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/009 (20130101)
G06T 5/40 (20130101) Original (OR) Class
G06T 2207/20072 (20130101)
G06T 2207/20208 (20130101)

Pictorial Communication, e.g Television
H04N 5/2355 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008374 Ouyang et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Zheng Ouyang (West Lafayette, Indiana);  Robert Graham Cooks (West Lafayette, Indiana);  Sandilya Venkata Garimella (West Lafayette, Indiana);  Jason David Harper (Lafayette, Indiana);  Nicholas Alan Charipar (Batavia, Indiana)
ABSTRACT The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
FILED Tuesday, November 01, 2016
APPL NO 15/340355
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/10 (20130101)
H01J 49/26 (20130101)
H01J 49/0404 (20130101) Original (OR) Class
H01J 49/0409 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008623 Cornfeld et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Space Vehicles Directorate Contracting Division (AFRL/RVK)
APPLICANT(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
ASSIGNEE(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
INVENTOR(S) Arthur Cornfeld (Sandy Springs, Georgia);  Jeff Steinfeldt (Albuquerque, New Mexico)
ABSTRACT The present disclosure provides a method of manufacturing a solar cell that includes providing a semiconductor growth substrate; depositing on said growth substrate a sequence of layers of semiconductor material forming a solar cell; applying a metal contact layer over said sequence of layers; affixing the adhesive polyimide surface of a permanent supporting substrate directly over said metal contact layer and permanently bonding it thereto by a thermocompressive technique; and removing the semiconductor growth substrate.
FILED Tuesday, March 31, 2015
APPL NO 14/674627
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/048 (20130101)
H01L 31/184 (20130101)
H01L 31/0304 (20130101)
H01L 31/0725 (20130101) Original (OR) Class
H01L 31/1844 (20130101)
H01L 31/1848 (20130101)
H01L 31/1856 (20130101)
H01L 31/1892 (20130101)
H01L 31/03048 (20130101)
H01L 31/06875 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/544 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/521 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008629 Northrup et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) John E. Northrup (Palo Alto, California);  Christopher L. Chua (San Jose, California);  Michael A. Kneissl (Berlin, Germany);  Thomas Wunderer (Palo Alto, California);  Noble M. Johnson (Menlo Park, California)
ABSTRACT Light emitting devices having an enhanced degree of polarization, PD, and methods for fabricating such devices are described. A light emitting device may include a light emitting region that is configured to emit light having a central wavelength, λ, and a degree of polarization, PD, where PD>0.006λ−b for 200 nm≤λ≤400 nm, wherein b≤1.5.
FILED Monday, February 01, 2016
APPL NO 15/012502
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 33/04 (20130101)
H01L 33/0025 (20130101) Original (OR) Class
H01L 33/32 (20130101)
H01L 33/0075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008711 Rolison et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Debra R Rolison (Arlington, Virginia);  Joseph F. Parker (Washington, District of Columbia);  Jeffrey W Long (Alexandria, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Debra R Rolison (Arlington, Virginia);  Joseph F. Parker (Washington, District of Columbia);  Jeffrey W Long (Alexandria, Virginia)
ABSTRACT An article having a continuous network of zinc and a continuous network of void space interpenetrating the zinc network. The zinc network is a fused, monolithic structure. A method of: providing an emulsion having a zinc powder and a liquid phase; drying the emulsion to form a sponge; sintering the sponge to form a sintered sponge; heating the sintered sponge in an oxidizing atmosphere to form an oxidized sponge having zinc oxide on the surface of the oxidized sponge; and electrochemically reducing the zinc oxide to form a zinc metal sponge.
FILED Friday, March 15, 2013
APPL NO 13/832576
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/42 (20130101)
H01M 4/043 (20130101)
H01M 4/0471 (20130101) Original (OR) Class
H01M 4/628 (20130101)
H01M 12/085 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/128 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008778 Jones, III
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Thomas O. Jones, III (San Diego, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Thomas O. Jones, III (San Diego, California)
ABSTRACT An antenna array comprising: four dipole antennas configured to function together as a directional, near vertical incidence skywave (NVIS) antenna with reduced side lobes, wherein each dipole antenna comprises two conductive elements and a feed point disposed between the two conductive elements, wherein the conductive elements of each of the four dipole antennas are disposed in an x-y plane of an x-y-z mutually orthogonal axes coordinate system, and wherein the conductive elements are substantially parallel with the x-axis and the x-y plane is substantially parallel with a ground plane; and wherein the feed points of the four dipole antennas are positioned on the x-y plane at approximately (x, 0), (−x, 0), (0, y), and (0, −y), and wherein the x-y plane is separated from the ground plane by a distance h that is less than or equal to 1/10 the wavelength (λ) of an operating frequency.
FILED Friday, August 29, 2014
APPL NO 14/472941
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 9/16 (20130101) Original (OR) Class
H01Q 21/26 (20130101)
H01Q 21/062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009014 Hairston
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Allen W Hairston (Andover, Massachusetts)
ABSTRACT A compact signal averaging circuit having an input, a first switch operatively connected to the input, a second switch operatively connected to the first switch, wherein the first switch is coupled to the circuit between the input and the second switch, a first FET having a gate, a source and a drain, wherein the gate is operatively connected to the circuit between the first switch and the second switch, a second FET comprising a gate, a source and a drain, wherein the source is operatively connected to a voltage supply and to the second switch, and an output operatively connected to the first FET drain and the second FET drain.
FILED Thursday, August 03, 2017
APPL NO 15/668119
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Electric Digital Data Processing
G06F 7/70 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 19/004 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009038 Chen
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Shuo-Wei Chen (South Pasadena, California)
ABSTRACT An analog-to-digital converter may convert an analog signal into digital codes representative of the changing level of the analog signal. An analog high pass filter may receive and continuously differentiate the analog signal. A voltage controlled oscillator may receive the differentiated analog signal and continuously generates an output that is an integral of the differentiated analog signal in the phase domain. A time-to-digital converter may sample the output of the voltage controlled oscillator and convert each sample into a digital code representative of the current phase of the sampled output of the voltage controlled oscillator.
FILED Wednesday, September 02, 2015
APPL NO 15/507704
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 1/10 (20130101)
H03M 1/14 (20130101)
H03M 1/60 (20130101)
H03M 1/502 (20130101)
H03M 1/0609 (20130101)
H03M 1/1245 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009103 Vahala et al.
FUNDED BY
Department of Commerce (DOC)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
INVENTOR(S) Kerry Vahala (Pasadena, California);  Scott Diddams (Boulder, Colorado);  Jiang Li (Pasadena, California);  Xu Yi (Pasadena, California);  Hansuek Lee (Pasadena, California)
ABSTRACT A microwave-frequency source at frequency fM comprises: a dual optical-frequency reference source, an electro-optic sideband generator, an optical bandpass filter, an optical detector, a reference oscillator, an electrical circuit, and a voltage-controlled oscillator (VCO). The sideband generator modulates dual optical reference signals at v2 and v1 to generate sideband signals at v1±n1fM and v2±n2fM. The bandpass filter transmits sideband signals at v1+N1fM and v2−N2fM. The optical detector generates a beat note at (v2−N2fM)−(v1+N1fM). The beat note and a reference oscillator signal are processed by the circuit to generate a loop-filtered error signal to input to the VCO. Output of the VCO at fM drives the sideband generator and forms the microwave-frequency output signal. The resultant frequency division results in reduced phase noise on the microwave-frequency signal.
FILED Thursday, August 11, 2016
APPL NO 15/235075
ART UNIT 2637 — Optical Communications
CURRENT CPC
Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 17/00 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/08 (20130101)
H03L 7/16 (20130101)

Transmission
H04B 10/503 (20130101)
H04B 10/2504 (20130101)
H04B 10/2507 (20130101) Original (OR) Class
H04B 10/2575 (20130101)
H04B 2210/006 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0075 (20130101)
H04L 7/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009115 Caplan
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) David O. Caplan (Westford, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David O. Caplan (Westford, Massachusetts)
ABSTRACT The present invention provides a simple means of demodulating optical signals, e.g. wideband M-ary orthogonal. The demodulator comprises an optical processor and a comparison module. The optical processor transforms M input optical signals into 2 log2(M) intermediary optical signals and the comparison module determines the logical representation of the input data based on log2(M) binary comparisons of the optical power of the intermediary signals. Example embodiments may be reconfigurable to receive optical signals using M-FSK, M-PPM, M-PolSK, and hybrid M-ary orthogonal modulation formats. Example embodiments also offer small size, weight and power consumption for both free-space and fiber optic environments as well as improved receiver sensitivity and reduced electron bandwidth requirements.
FILED Wednesday, May 02, 2012
APPL NO 13/462555
ART UNIT 2637 — Optical Communications
CURRENT CPC
Transmission
H04B 10/67 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009202 Valdes Garcia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Alberto Valdes Garcia (Chappaqua, New York);  Wayne H. Woods, Jr. (Burlington, Massachusetts);  Bodhisatwa Sadhu (Fishkill, New York)
ABSTRACT An apparatus for decoding a data modulated signal includes a signal receiver that receives a data modulated signal that is encoded with phase-shift keying (PSK) and provides an amplified signal corresponding to the data modulated signal, a tunable phase shifter that receives a local reference signal and a selected phase shift, applies the selected phase shift to the local reference signal to produce a phase shifted reference signal, a summing unit that sums the amplified signal and the phase shifted reference signal to produce a summed signal, an amplitude detector that determines an amplitude of the summed signal, and a symbol detector that varies the selected phase shift and determines a current symbol within the data modulated signal based on the amplitude of the summed signal as the selected phase shift is varied. A corresponding method is also disclosed herein.
FILED Monday, August 14, 2017
APPL NO 15/675887
ART UNIT 2631 — Digital Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009259 Calmon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Flavio du Pin Calmon (White Plains, New York);  Jason M. Cloud (Cambridge, Massachusetts);  Muriel Médard (Belmont, Massachusetts);  Weifei Zeng (Cambridge, Massachusetts)
ABSTRACT Techniques, devices, systems, and protocols are disclosed herein that relate to data transfer between communication nodes via multiple heterogeneous paths. In various embodiments, network coding may be used to improve data flow and reliability in a multiple path scenario. Transmission control protocol (TCP) may also be used within different paths to further enhance data transfer reliability. In some embodiments, multiple levels of network coding may be provided within a transmitter in a multiple path scenario, with one level being applied across all paths and another being applied within individual paths.
FILED Tuesday, November 22, 2016
APPL NO 15/358776
ART UNIT 2477 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 7/15521 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0041 (20130101)
H04L 1/0076 (20130101)
H04L 45/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009738 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Jianqiang Shen (Santa Clara, California);  Oliver Brdiczka (Mountain View, California)
ABSTRACT A computer-implemented system and method for determining an appropriate time for providing a message to a driver are provided. A message is received for a driver of a motor vehicle. Movement of the motor vehicle is monitored, and a familiarity of the movement to the driver is determined. Data sensed by the motor vehicle is obtained, and a cognitive load of the driver is calculated based on the familiarity of the movement and the sensed data. The message is provided to the driver when the calculated cognitive load is low.
FILED Tuesday, December 23, 2014
APPL NO 14/581975
ART UNIT 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 40/08 (20130101)
B60W 2040/0818 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/04 (20130101)
G06Q 10/109 (20130101)
G06Q 50/30 (20130101)

Wireless Communication Networks
H04W 4/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10004800 Haynes et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Duke University (Durham, North Carolina);  Los Alamos National Security, LLC (Los Alamos, New Mexico);  The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania);  Trustees of Boston University (Boston, Massachusetts);  The United States of America as Represented by The Secretary of the Department of Health and Human Services (Washington, District of Columbia);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) Duke University (Durham, North Carolina);  Los Alamos National Security, LLC (Los Alamos, New Mexico);  The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania);  Trustees of Boston University (Boston, Massachusetts);  The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer (Washington, District of Columbia);  The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Barton F. Haynes (Durham, North Carolina);  Hua-Xin Liao (Durham, North Carolina);  Rebecca M. Lynch (Rockville, Maryland);  Tongqing Zhou (Rockville, Maryland);  Feng Gao (Durham, North Carolina);  Scott Boyd (Palo Alto, California);  George M. Shaw (Philadelphia, Pennsylvania);  Beatrice H. Hahn (Philadelphia, Pennsylvania);  Thomas B. Kepler (Boston, Massachusetts);  Bette T. Korber (Los Alamos, New Mexico);  Peter Kwong (Rockville, Maryland);  John Mascola (Rockville, Maryland)
ABSTRACT The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).
FILED Thursday, September 12, 2013
APPL NO 14/427581
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/21 (20130101) Original (OR) Class
A61K 2039/57 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/15022 (20130101)
C12N 2740/16022 (20130101)
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005018 Hayes et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) James C. Hayes (Richland, Washington);  Paul H. Humble (Richland, Washington);  Mark E. Panisko (Richland, Washington);  Warren W. Harper (Richland, Washington);  Timothy L. Stewart (Pendleton, Oregon)
ABSTRACT A method and system for collecting xenon (Xe) is described. A microchannel heat exchanger is used in combination with a mechanical cooler and an absorbent. A combination of components makes up a Xe Collection Subsystem that is adapted for use in an efficient process for collecting, purifying, and measuring Xe isotopes collected from air as part of the International Monitoring System.
FILED Friday, September 02, 2016
APPL NO 15/256403
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 46/0036 (20130101)
B01D 53/00 (20130101)
B01D 53/047 (20130101)
B01D 53/261 (20130101)
B01D 53/0438 (20130101) Original (OR) Class
B01D 2253/102 (20130101)
B01D 2253/104 (20130101)
B01D 2256/18 (20130101)
B01D 2257/11 (20130101)
B01D 2259/416 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 23/0052 (20130101)
C01B 23/0057 (20130101)
C01B 23/0063 (20130101)
C01B 2210/0015 (20130101)
C01B 2210/0017 (20130101)
C01B 2210/0037 (20130101)
C01B 2210/0048 (20130101)
C01B 2210/0051 (20130101)
C01B 2210/0062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005077 Tsapatsis et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Michael Tsapatsis (Edina, Minnesota);  Kumar Varoon Agrawal (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Michael Tsapatsis (Edina, Minnesota);  Kumar Varoon Agrawal (Minneapolis, Minnesota)
ABSTRACT Oxide materials, thin films, coatings, and methods of preparing the same are disclosed herein. In certain embodiments the oxide material can have an MWW type framework or an MFI type framework. In one embodiment, the method includes: providing a suspension of an exfoliated layered oxide material in a solvent; and filtering the suspension through a porous support to provide a film of the oxide material, optionally directly on the porous support. Secondary grown films of the oxide material and methods of preparing the same are also provided. Thin zeolite films are attractive for a wide range of applications including molecular sieve membranes and catalytic membrane reactors, permeation barriers, low dielectric constant materials for microelectronics and sensor components for selective sensing.
FILED Tuesday, July 03, 2012
APPL NO 14/130589
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Separation
B01D 53/228 (20130101)
B01D 67/0046 (20130101)
B01D 67/0051 (20130101)
B01D 67/0076 (20130101)
B01D 69/12 (20130101)
B01D 71/024 (20130101)
B01D 71/027 (20130101)
B01D 71/028 (20130101)
B01D 2323/08 (20130101)
B01D 2325/04 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/26 (20130101) Original (OR) Class
B01J 37/0215 (20130101)
B01J 2231/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 39/026 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/34 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 29/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005674 Tsapatsis et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Michael Tsapatsis (Minneapolis, Minnesota);  Kumar Varoon Agrawal (Minneapolis, Minnesota);  Lorraine Francis (Minneapolis, Minnesota)
ABSTRACT A process for making a mechanically strong, high permeance, and relatively inexpensive support structure for zeolite membranes is described. In an example implementation, a process includes forming a silica powder from silica fibers, mixing the silica powder and a polymer solution to form a mixture, forming the mixture into a shaped mixture, and sintering the shaped mixture to form a silica support.
FILED Thursday, July 10, 2014
APPL NO 14/327720
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 33/12 (20130101)
C01B 33/18 (20130101) Original (OR) Class

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2101/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005699 Amonette et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S) James E. Amonette (Richland, Washington);  Josef Matyas (Richland, Washington)
ABSTRACT A controlled-release solid nitride fertilizer from fly ash and a method for making are described. The fertilizer includes a nitrogen source including at least one solid nitride combined with at least one precipitation-inhibiting agent and with at least one moisture-retention agent, all compressed together to form a porous release structure that in contact with water releases ammonium ions as a nitrogen nutrient at a substantially uniform release rate over a selected release period and thereby maximizes nitrogen-use efficiency by plants.
FILED Thursday, July 28, 2016
APPL NO 15/222632
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Nitrogenous Fertilisers
C05C 11/00 (20130101)

Mixtures of Fertilisers Covered Individually by Different Subclasses of Class C05; Mixtures of One or More Fertilisers With Materials Not Having a Specific Fertilising Activity, e.g Pesticides, Soil-conditioners, Wetting Agents; Fertilisers Characterised by Their Form
C05G 3/0094 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005700 Beck et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Virent, Inc. (Madison, Wisconsin)
ASSIGNEE(S) Virent, Inc. (Madison, Wisconsin)
INVENTOR(S) Taylor Beck (Madison, Wisconsin);  Brian Blank (Monona, Wisconsin);  Casey Jones (Madison, Wisconsin);  Elizabeth Woods (Middleton, Wisconsin);  Randy Cortright (Madison, Wisconsin)
ABSTRACT Methods, catalysts, and reactor systems for producing in high yield aromatic chemicals and liquid fuels from a mixture of oxygenates comprising di- and polyoxygenates are disclosed. Also disclosed are methods, catalysts, and reactor systems for producing aromatic chemicals and liquid fuels from oxygenated hydrocarbons such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like; and methods, catalysts, and reactor systems for producing the mixture of oxygenates from oxygenated hydrocarbons such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like. The disclosed catalysts for preparing the mixture of oxygenates comprise a Group VIII metal and a crystalline alumina support.
FILED Wednesday, August 10, 2016
APPL NO 15/233466
ART UNIT 1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/066 (20130101)
B01J 23/14 (20130101)
B01J 23/755 (20130101)
B01J 23/835 (20130101)
B01J 23/888 (20130101)
B01J 23/6527 (20130101)
B01J 29/46 (20130101)
B01J 29/90 (20130101)
B01J 37/0201 (20130101)
B01J 37/0213 (20130101)
B01J 38/02 (20130101)
B01J 38/12 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 35/06 (20130101) Original (OR) Class

Acyclic or Carbocyclic Compounds
C07C 1/24 (20130101)
C07C 1/2072 (20130101)
C07C 29/60 (20130101)
C07C 45/002 (20130101)
C07C 51/377 (20130101)

Heterocyclic Compounds
C07D 301/02 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 3/46 (20130101)
C10G 3/47 (20130101)
C10G 3/48 (20130101)
C10G 3/49 (20130101)
C10G 3/50 (20130101)
C10G 2300/1014 (20130101)
C10G 2400/30 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/584 (20151101)
Y02P 20/588 (20151101)
Y02P 30/20 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005796 Briseno et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Alejandro L. Briseno (Amherst, Massachusetts);  Lei Zhang (Amherst, Massachusetts)
ABSTRACT We report the synthesis and characterization of novel bistetracenes, an unconventional, linearly extended conjugated core with eight fused rings. Also described are bisoligoacenes. In general, the properties and stability of large polycyclic aromatic hydrocarbons (PAHs) strongly depend on the mode of ring annellation and the topology of their it-electron systems, which are usually associated with the resonance stabilization energy in large PAHs.
FILED Friday, May 01, 2015
APPL NO 15/307968
ART UNIT 1671 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/0809 (20130101) Original (OR) Class
C07F 7/0827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005825 Agadjanyan et al.
FUNDED BY
Department of Energy (DOE)
Institute for Molecular Medicine (IMMED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) INSTITUTE FOR MOLECULAR MEDCINE, INC. (Huntington Beach, California)
ASSIGNEE(S) INSTITUTE FOR MOLECULAR MEDICINE, INC. (Huntington Beach, California)
INVENTOR(S) Michael G. Agadjanyan (Huntington Beach, California);  Anahit Ghochikyan (Huntington Beach, California)
ABSTRACT Disclosed are compositions, comprising one or more immunogens, wherein each immunogen comprises at least two regions, wherein one region comprises at least one amyloid-β (Aβ) B cell epitope or at least one Tau B cell epitope or at least one α-synuclein B cell epitope or combinations thereof, and a second region comprises at least one foreign T helper cell (Th) epitope, and usually multiple foreign Th epitopes. Methods of making and using the compositions are also disclosed.
FILED Friday, February 20, 2015
APPL NO 14/628023
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/0007 (20130101)
A61K 2039/53 (20130101)
A61K 2039/57 (20130101)
A61K 2039/70 (20130101)
A61K 2039/575 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 14/47 (20130101)
C07K 14/4711 (20130101) Original (OR) Class
C07K 2319/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005974 Lilga et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Michael A. Lilga (Richland, Washington);  Richard T. Hallen (Richland, Washington);  Karl O. Albrecht (Richland, Washington);  Alan R. Cooper (Kennewick, Washington);  John G. Frye (Richland, Washington);  Karthikeyan Kallupalayam Ramasamy (West Richland, Washington)
ABSTRACT Systems, processes, and catalysts are disclosed for obtaining fuels and fuel blends containing selected ratios of open-chain and closed-chain fuel-range hydrocarbons suitable for production of alternate fuels including gasolines, jet fuels, and diesel fuels. Fuel-range hydrocarbons may be derived from ethylene-containing feedstocks and ethanol-containing feedstocks.
FILED Friday, August 18, 2017
APPL NO 15/681154
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 2/12 (20130101)
C07C 2/24 (20130101)
C07C 2/66 (20130101)
C07C 5/03 (20130101)
C07C 2521/04 (20130101)
C07C 2521/12 (20130101)
C07C 2523/42 (20130101)
C07C 2523/755 (20130101)
C07C 2529/06 (20130101)
C07C 2529/40 (20130101)
C07C 2529/70 (20130101)
C07C 2529/76 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 3/00 (20130101)
C10G 29/205 (20130101)
C10G 45/00 (20130101)
C10G 50/00 (20130101)
C10G 69/123 (20130101)
C10G 69/126 (20130101)
C10G 2300/1081 (20130101)
C10G 2300/1092 (20130101)
C10G 2300/1096 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/04 (20130101) Original (OR) Class
C10L 2200/0469 (20130101)
C10L 2270/02 (20130101)
C10L 2270/04 (20130101)
C10L 2290/24 (20130101)
C10L 2290/543 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 30/42 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005999 Larimer et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S) Curtis J. Larimer (Richland, Washington);  Jonathan D. Suter (Richland, Washington);  Raymond S. Addleman (Benton City, Washington);  George T. Bonheyo (Sequim, Washington);  Michelle R. Brann (Richland, Washington)
ABSTRACT An apparatus and method of measuring biofilm and biological activity on a surface is disclosed. The apparatus includes a biofilm, which includes one or more microorganisms, grown on a substrate. A viewing window is placed on a surface of the biofilm and a gas bubble is introduced between the viewing window and the surface of the biofilm. The space between the substrate and the viewing window may be enclosed in a casing that has an inlet and an outlet, forming a flow cell. A microscope system, such as a white light interferometer, captures data of the biofilm in situ and non-destructively. The 3D images of biofilm surface have high resolution while maintaining a large field of view. The apparatuses and methods will be useful for fundamental studies of biofilms, biomedical and environmental screening, and many other applications in biology and the life sciences.
FILED Wednesday, March 16, 2016
APPL NO 15/071921
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/12 (20130101)
C12M 23/22 (20130101)
C12M 23/58 (20130101)
C12M 29/10 (20130101)
C12M 41/36 (20130101)
C12M 41/46 (20130101) Original (OR) Class
C12M 41/48 (20130101)

Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/0209 (20130101)
G01B 9/02021 (20130101)
G01B 11/0675 (20130101)
G01B 11/2441 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006012 Maiyuran et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Novozymes, Inc. (Davis, California)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Suchindra Maiyuran (Gold River, California);  Randall Kramer (Lincoln, California);  Paul Harris (Carnation, Washington)
ABSTRACT The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED Monday, October 20, 2014
APPL NO 14/518841
ART UNIT 1663 — Plants
CURRENT CPC
Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol
C11D 3/386 (20130101)
C11D 3/3869 (20130101)
C11D 3/38645 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2437 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101)
C12P 19/14 (20130101)

Enzymes
C12Y 302/01 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006015 Liu et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Novozymes Inc. (Davis, California)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Ye Liu (Beijing, China PRC);  Lan Tang (Beijing, China PRC);  Yu Zhang (Beijing, China PRC);  Junxin Duan (Beijing, China PRC)
ABSTRACT The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED Tuesday, March 21, 2017
APPL NO 15/465373
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2434 (20130101)
C12N 9/2482 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/10 (20130101)
C12P 19/02 (20130101)
C12P 19/14 (20130101)
C12P 2203/00 (20130101)

Enzymes
C12Y 302/01008 (20130101)
C12Y 302/01037 (20130101)

Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor
D21C 5/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006033 Liao et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) James C. Liao (Los Angeles, California);  Igor Bogorad (Tarzana, California)
ABSTRACT Provided are microorganisms that catalyze the synthesis of chemicals and biochemicals from a methanol, methane and/or formaldehyde. Also provided are methods of generating such organisms and methods of synthesizing chemicals and biochemicals using such organisms.
FILED Monday, September 14, 2015
APPL NO 14/853946
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101)
C12N 9/1022 (20130101)
C12N 15/52 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/06 (20130101)
C12P 7/16 (20130101)

Enzymes
C12Y 202/01003 (20130101)
C12Y 401/02009 (20130101)
C12Y 401/02022 (20130101)
C12Y 401/02043 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)
Y02E 50/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006038 Raab et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Agrivida, Inc. (Medford, Massachusetts)
ASSIGNEE(S) AGRIVIDA, INC. (Medford, Massachusetts)
INVENTOR(S) R. Michael Raab (Arlington, Massachusetts);  Dongcheng Zhang (Medford, Massachusetts);  Oleg Bougri (Boise, Idaho)
ABSTRACT Methods for consolidated pretreatment and hydrolysis of genetically engineered plants expressing cell wall degrading enzymes are provided. Expression cassettes and vectors for making transgenic plants are described. Plants engineered to express one or more cell wall degrading enzymes using expression cassettes and vectors of the invention are also provided.
FILED Monday, December 07, 2015
APPL NO 14/961426
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/248 (20130101)
C12N 9/2437 (20130101)
C12N 9/2445 (20130101)
C12N 15/8216 (20130101)
C12N 15/8246 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/14 (20130101)

Enzymes
C12Y 302/01004 (20130101)
C12Y 302/01008 (20130101)
C12Y 302/01021 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)
Y02E 50/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006039 Benning et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Christoph Benning (East Lansing, Michigan);   Sanjaya (East Lansing, Michigan);  Changcheng Xu (East Lansing, Michigan)
ABSTRACT The present invention relates to compositions and methods for providing RNA interference (RNAi) vectors comprising trigalactosyldiacylglycerol (tgd) biosynthesis enzyme constructs for increasing oil content of plants. Further, the use of tgd RNAi silencing vectors in combination with co-expression of heterologous oil regulating transcription factors, such as WRINKLED1, are contemplated to overcome the reduced growth and variable levels of embryonic lethality in plants with reduced TGD protein. Additionally, plants having reduced APS1, a gene encoding a major catalytic isoform of the small subunit of AGPase (AGP(−) plants), co-expressing a heterologous oil modulating transcription factor are contemplated for use in combination with plants having reduced TGD. Oil harvested from vegetative tissues of plants comprising vectors and genes of the present invention is contemplated for use in biofuel and biodiesel products.
FILED Friday, October 04, 2013
APPL NO 14/046504
ART UNIT 1662 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101)
C12N 9/1241 (20130101)
C12N 15/8218 (20130101)
C12N 15/8247 (20130101) Original (OR) Class

Enzymes
C12Y 207/07027 (20130101)
C12Y 306/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006057 Piotrowski et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Jeff S. Piotrowski (Madison, Wisconsin);  Trey K. Sato (Madison, Wisconsin);  Chad L. Myers (Arden Hills, Minnesota)
ABSTRACT The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae having enhanced tolerance for gamma valerolactone (GVL) toxicity. Also provided are methods of using such genetically engineered yeast strains for improved GVL-mediated hydrolysis of lignocellulosic biomass for industrial-scale ethanol production.
FILED Wednesday, September 09, 2015
APPL NO 14/848440
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/14 (20130101)
C12N 15/81 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/10 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006065 Stephanopoulos et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Gregory Stephanopoulos (Winchester, Massachusetts);  Syed Hussain Imam Abidi (Boston, Massachusetts)
ABSTRACT Some aspects of this invention relate to methods useful for the conversion of a carbon source to a biofuel or biofuel precursor using engineered microbes. Some aspects of this invention relate to the discovery of a key regulator of lipid metabolism in microbes. Some aspects of this invention relate to engineered microbes for biofuel or biofuel precursor production.
FILED Monday, June 23, 2014
APPL NO 14/311527
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/001 (20130101)
C12N 9/0071 (20130101)
C12N 15/815 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/6409 (20130101) Original (OR) Class
C12P 7/6463 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006436 Caruso et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Christopher Daniel Caruso (Greenville, South Carolina);  Edward McBeth Stewart (Greenville, South Carolina);  Aaron Alpheus Yarbrough (Clemson, South Carolina)
ABSTRACT Rotor blades for a wind turbines include a structural support member disposed internal the rotor blade that extends for at least a portion of a rotor blade span length and an airfoil structure supported by the structural support member, the airfoil structure comprising a shell portion and at least one load-transferring exterior panel. The shell portion and the at least one load-transferring exterior panel combine to form an aerodynamic profile comprising a leading edge opposite a trailing edge and a pressure side opposite a suction side. Moreover, the shell portion and the at least one load-transferring exterior panel are independently connected to the structural support member.
FILED Thursday, December 18, 2014
APPL NO 14/574523
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Wind Motors
F03D 1/0675 (20130101) Original (OR) Class
F03D 13/10 (20160501)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/721 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007242 Fox et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Thomas W. Fox (Hopewell Junction, New York);  Hans M. Jacobson (White Plains, New York);  Ravi Nair (Briarcliff Manor, New York);  Bryan S. Rosenburg (Cortlandt Manor, New York)
ABSTRACT A computer detects a request by a process for access to a shadow control page, wherein the shadow control page allows the process access to one or more devices. The computer assigns the shadow control page and a key to the process associated with the request. The computer detects a request by the process via the assigned shadow control page for creation of a subset of devices from the one or more devices. The computer inputs information detailing an association between the subset of devices and the assigned key into a subset definition table, wherein the subset definition table includes one or more keys and one or more corresponding subsets.
FILED Thursday, June 11, 2015
APPL NO 14/736758
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 15/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007996 Paglieroni et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (, None)
INVENTOR(S) David W. Paglieroni (Pleasanton, California);  N. Reginald Beer (Pleasanton, California)
ABSTRACT A detection system that detects subsurface objects within a medium and estimates various features of the objects is provided. The detection system receives a streaming sequence of image frames of the medium at various along-medium locations. An image frame contains voxel values (intensities) representing characteristics of the medium across the medium and in the depth (range) direction. The detection system depth-compensates the intensities for determining which voxels are part of an object using an unsupervised binary classifier. The detection system then connects object voxels into distinct objects and recursively estimates the features of those objects as the image frames stream based on the locations and intensities of the object voxels.
FILED Monday, March 02, 2015
APPL NO 14/635822
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/411 (20130101)
G01S 13/885 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/12 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00201 (20130101)
G06K 9/3241 (20130101)
G06K 9/6267 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0081 (20130101) Original (OR) Class
G06T 7/194 (20170101)
G06T 15/08 (20130101)
G06T 2207/10028 (20130101)

Pictorial Communication, e.g Television
H04N 13/128 (20180501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007999 Hamann et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Hendrik F. Hamann (Yorktown Heights, New York);  Levente Klein (Tuckahoe, New York);  Siyuan Lu (Yorktown Heights, New York);  Theodore G. van Kessel (Millbrook, New York)
ABSTRACT Techniques for estimating direct and diffuse sunlight reaching a location as a function of time using color whole sky images are provided. In one aspect, a method for forecasting solar insolation is provided that includes the steps of: obtaining color whole sky images using a digital camera which are taken at different times, and wherein an image of a solar disk is present in at least one of the color whole sky images; creating sky transparency images from the color whole sky images; determining atmospheric solar scattering based on a width of the solar disk in the color whole sky images; determining cloud motion trajectories from a time series of the sky transparency images; and calculating the solar insolation as a function of time using the sky transparency, the atmospheric solar scattering, and the cloud motion trajectories. A system for forecasting solar insolation is also provided.
FILED Wednesday, August 10, 2016
APPL NO 15/233412
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/20 (20130101) Original (OR) Class
G06T 2207/30192 (20130101)
G06T 2207/30241 (20130101)

Pictorial Communication, e.g Television
H04N 5/372 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008338 Stadermann et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Michael Stadermann (Pleasanton, California);  Theodore F. Baumann (Discovery Bay, California);  Alexander E. Gash (Brentwood, California);  Alex P. Parra (West Point, New York)
ABSTRACT Disclosed here is a method for increasing the hydrophilicity of a carbon aerogel, comprising heating the carbon aerogels under air or a gas having a higher concentration of oxygen than air at a temperature of about 200°-500° C. to obtain an activated carbon aerogel. Also disclosed include an activated carbon aerogel obtained by the method, an electrode comprising the activated carbon aerogel, and a supercapacitor or capacitive deionization device comprising the electrode.
FILED Wednesday, January 13, 2016
APPL NO 14/994854
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/4691 (20130101)
C02F 2001/46133 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/24 (20130101)
H01G 11/34 (20130101) Original (OR) Class
H01G 11/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008618 Haight et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Richard A. Haight (Mahopac, New York);  James B. Hannon (Lake Lincolndale, New York);  Satoshi Oida (Yorktown Heights, New York)
ABSTRACT A method for forming a back contact on an absorber layer in a photovoltaic device includes forming a two dimensional material on a first substrate. An absorber layer including Cu—Zn—Sn—S(Se) (CZTSSe) is grown over the first substrate on the two dimensional material. A buffer layer is grown on the absorber layer on a side opposite the two dimensional material. The absorber layer is exfoliated from the two dimensional material to remove the first substrate from a backside of the absorber layer opposite the buffer layer. A back contact is deposited on the absorber layer.
FILED Tuesday, July 25, 2017
APPL NO 15/658790
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0324 (20130101)
H01L 31/0326 (20130101)
H01L 31/1892 (20130101)
H01L 31/03923 (20130101)
H01L 31/03925 (20130101)
H01L 31/03926 (20130101)
H01L 31/022441 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008653 Joshi et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas);  U.S. DEPARTMENT OF ENERGY (Washington, District of Columbia)
INVENTOR(S) Giri Joshi (Maynard, Massachusetts);  Jian Yang (Brookline, Massachusetts);  Michael Engber (Boston, Massachusetts);  Tej Pantha (Waltham, Massachusetts);  Martin Cleary (Somerville, Massachusetts);  Zhifeng Ren (Houston, Texas);  Ran He (Houston, Texas);  Boris Kozinsky (Waban, Massachusetts)
ABSTRACT A thermoelectric half-Heusler material comprising niobium (Nb), iron (Fe) and antimony (Sb) wherein the material comprises grains having a mean grain size less than one micron. A method of making a nanocomposite half-Heusler thermoelectric material includes melting constituent elements of the thermoelectric material to form an alloy of the thermoelectric material, comminuting (e.g., ball milling) the alloy of the thermoelectric material into nanometer scale mean size particles, and consolidating the nanometer size particles to form the half-Heusler thermoelectric material comprising at least niobium (Nb), iron (Fe) and antimony (Sb) and having grains with a mean grain size less than one micron.
FILED Tuesday, March 24, 2015
APPL NO 14/667056
ART UNIT 1758 — Semiconductors/Memory
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/14 (20130101)
B22F 9/08 (20130101)
B22F 2003/248 (20130101)
B22F 2009/043 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)

Alloys
C22C 1/04 (20130101)
C22C 12/00 (20130101)
C22C 33/0278 (20130101)
C22C 38/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/18 (20130101) Original (OR) Class
H01L 35/20 (20130101)
H01L 35/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008738 Dai et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Sheng Dai (Knoxville, Tennessee);  Jinshui Zhang (Oak Ridge, Tennessee);  Xiao-Guang Sun (Knoxville, Tennessee)
ABSTRACT A nanoconfined metal-containing electrolyte comprising a layer of enclosed nanostructures in which each enclosed nanostructure contains a liquid metal-containing electrolyte, wherein said enclosed nanostructures are in physical contact with each other. Metal-ion batteries containing the nanoconfined electrolyte in contact with an anode and cathode of the battery are also described. Methods for producing the nanoconfined electrolyte are also described.
FILED Wednesday, September 02, 2015
APPL NO 14/843559
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/052 (20130101)
H01M 10/054 (20130101)
H01M 10/056 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008743 Krumdick et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Gregory K. Krumdick (Homer Glen, Illinois);  Trevor L. Dzwiniel (Carol Stream, Illinois);  Krzysztof Pupek (Plainfield, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Gregory K. Krumdick (Homer Glen, Illinois);  Trevor L. Dzwiniel (Carol Stream, Illinois);  Krzysztof Pupek (Plainfield, Illinois)
ABSTRACT The invention provides a method for producing a molecule capable of undergoing reduction-oxidation when subjected to a voltage potential, the method comprising phosphorylating hydroquinone to create a first intermediate; rearranging the first intermediate to an aryl-bis-(phosphonate) thereby creating a second intermediate comprising phosphorous alkoxy groups; alkylating (e.g., methylating) the second intermediate; converting the alkoxy groups to halides; and substituting the halides to alkyl or aryl groups. Also provided is a system for preventing overcharge in a Lithium-ion battery, the method comprising a mixture of a redox shuttle with electrolyte in the battery such that the shuttle comprises between about 10 and about 20 weight percent of the mixture.
FILED Monday, February 03, 2014
APPL NO 14/171556
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/12 (20130101)
C07F 9/42 (20130101)
C07F 9/4021 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0525 (20130101)
H01M 10/0567 (20130101) Original (OR) Class
H01M 10/4235 (20130101)
H01M 2300/0025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008979 Gilchrist et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Phil Gilchrist (Austin, Texas);  William Morris (Round Rock, Texas);  Kristine Little (Austin, Texas);  Patrick Chapman (Austin, Texas);  William P. Mulligan (Wilson, Wyoming);  Marco A. Marroquin (Austin, Texas)
ASSIGNEE(S) SunPower Corporation (San Jose, California)
INVENTOR(S) Phil Gilchrist (Austin, Texas);  William Morris (Round Rock, Texas);  Kristine Little (Austin, Texas);  Patrick Chapman (Austin, Texas);  William P. Mulligan (Wilson, Wyoming);  Marco A. Marroquin (Austin, Texas)
ABSTRACT Various technologies for integrating a microinverter with a photovoltaic module are disclosed. An alternating current photovoltaic (ACPV) module includes a photovoltaic module having a frame and a junction box including a direct current (DC) output connector, and a microinverter having a housing coupled to the frame and a DC input connector electrically mated with the DC output connector of the photovoltaic module.
FILED Wednesday, November 26, 2014
APPL NO 14/554825
ART UNIT 1758 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/02013 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 40/32 (20141201) Original (OR) Class
H02S 40/34 (20141201)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 3/301 (20130101)
H05K 7/02 (20130101)
H05K 7/04 (20130101)
H05K 7/142 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009002 Branch et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Darren W. Branch (Albuquerque, New Mexico);  Roy H. Olsson (Albuquerque, New Mexico)
ABSTRACT The present invention relates to methods for suppressing spurious modes in microresonators. In particular embodiments, such spurious modes can be reduced by providing one or more structural components that effectively reduce the acoustic velocity in the transducer domain. Additional methods and microresonators are described herein.
FILED Wednesday, August 17, 2016
APPL NO 15/239662
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Impedance Networks, e.g Resonant Circuits; Resonators
H03H 3/02 (20130101)
H03H 3/007 (20130101)
H03H 3/08 (20130101)
H03H 9/02086 (20130101)
H03H 9/02228 (20130101) Original (OR) Class
H03H 9/02818 (20130101)
H03H 2009/02503 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009526 Kisner et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Roger A. Kisner (Knoxville, Tennessee);  Timothy J. McIntyre (Farragut, Tennessee);  Vincent C. Paquit (Knoxville, Tennessee)
ABSTRACT An exemplary device includes, on a longitudinal axis, an illumination-light source, an axicon (conic) mirror, an image sensor, and a tilted optical element. The light source provides illumination light propagating forwardly on the axis. The axicon mirror reflects the illumination light radially outward, relative to the axis, to the interior surface of a tube to produce reflected light propagating, from the illuminated interior surface, as imaging light back to the axicon, which reflects the imaging light rearwardly. The image sensor receives at least a portion of the imaging light rearwardly reflected by the axicon mirror. The tilted optical element, situated between the axicon mirror and the interior surface, moves a selected first portion of the imaging light away from being incident on the image sensor, while allowing a second portion of the imaging light to be incident on the image sensor.
FILED Thursday, February 13, 2014
APPL NO 14/180062
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/001 (20130101)
G02B 5/10 (20130101)
G02B 23/243 (20130101)
G02B 23/2461 (20130101)
G02B 23/2476 (20130101)
G02B 23/2484 (20130101)

Pictorial Communication, e.g Television
H04N 5/2252 (20130101)
H04N 5/2256 (20130101) Original (OR) Class
H04N 2005/2255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE46921 Zhu et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) OneD Material LLC (Palo Alto, California)
ASSIGNEE(S) OneD Material LLC (Palo Alto, California)
INVENTOR(S) Yimin Zhu (Fremont, California);  Jay L. Goldman (Mountain View, California);  Baixin Qian (Cupertino, California);  Ionel C. Stefan (San Jose, California)
ABSTRACT The present invention relates to SiC nanostructures, including SiC nanopowder, SiC nanowires, and composites of SiC nanopowder and nanowires, which can be used as catalyst supports in membrane electrode assemblies and in fuel cells. The present invention also relates to composite catalyst supports comprising nanopowder and one or more inorganic nanowires for a membrane electrode assembly.
FILED Monday, September 28, 2015
APPL NO 14/868273
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101) Original (OR) Class

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/92 (20130101)
H01M 4/925 (20130101)
H01M 4/926 (20130101)
H01M 4/8605 (20130101)
H01M 4/8807 (20130101)
H01M 8/1011 (20130101)
H01M 2008/1095 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/523 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10004440 Cooks et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Zheng Ouyang (West Lafayette, Indiana);  Chien-Hsun Chen (West Lafayette, Indiana);  Ziqing Lin (West Lafayette, Indiana);  Livia Schiavinato Eberlin (Lafayette, Indiana)
ABSTRACT The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
FILED Thursday, June 08, 2017
APPL NO 15/617013
ART UNIT 2881 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1477 (20130101) Original (OR) Class

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 11/00 (20130101)
A61M 25/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/4833 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0022 (20130101)
H01J 49/34 (20130101)
H01J 49/167 (20130101)
H01J 49/0445 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005077 Tsapatsis et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Michael Tsapatsis (Edina, Minnesota);  Kumar Varoon Agrawal (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Michael Tsapatsis (Edina, Minnesota);  Kumar Varoon Agrawal (Minneapolis, Minnesota)
ABSTRACT Oxide materials, thin films, coatings, and methods of preparing the same are disclosed herein. In certain embodiments the oxide material can have an MWW type framework or an MFI type framework. In one embodiment, the method includes: providing a suspension of an exfoliated layered oxide material in a solvent; and filtering the suspension through a porous support to provide a film of the oxide material, optionally directly on the porous support. Secondary grown films of the oxide material and methods of preparing the same are also provided. Thin zeolite films are attractive for a wide range of applications including molecular sieve membranes and catalytic membrane reactors, permeation barriers, low dielectric constant materials for microelectronics and sensor components for selective sensing.
FILED Tuesday, July 03, 2012
APPL NO 14/130589
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Separation
B01D 53/228 (20130101)
B01D 67/0046 (20130101)
B01D 67/0051 (20130101)
B01D 67/0076 (20130101)
B01D 69/12 (20130101)
B01D 71/024 (20130101)
B01D 71/027 (20130101)
B01D 71/028 (20130101)
B01D 2323/08 (20130101)
B01D 2325/04 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/26 (20130101) Original (OR) Class
B01J 37/0215 (20130101)
B01J 2231/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 39/026 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/34 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 29/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005248 Khine et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michelle Khine (Irvine, California);  Jolie McLane (Newport Beach, California);  Nicole Mendoza (Newport Beach, California)
ABSTRACT This disclosure provides a monolithic mold including a plurality of lens forming features that can be used to simultaneously form a plurality of lenses with different sizes and shapes. The mold can be formed by disposing a polymeric material around a plurality of physical objects with different shapes and sized. A method of forming the mold includes providing a substrate that has a surface with regions of low and high wettability. Water is deposited on the surface such that water droplets are formed with different contact angles. The mold is formed around the droplets.
FILED Friday, September 19, 2014
APPL NO 14/491800
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0048 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2023/38 (20130101)
B29K 2105/0085 (20130101)
B29K 2883/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005719 Ferreira et al.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Eric Ferreira (Athens, Georgia);  Brian J Knight (Gainesville, Florida);  Qiankun Li (Taihe, China PRC)
ABSTRACT A method of preparing ortho-alkenyl and ortho-acetyl benzylic alcohols is disclosed.
FILED Thursday, March 31, 2016
APPL NO 15/088014
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 29/44 (20130101)
C07C 67/347 (20130101)
C07C 231/12 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 491/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005852 Kennedy et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Joseph Kennedy (Akron, Ohio);  Yongmoon Kwon (Copley, Ohio);  Subramanyam Ummadisetty (Longview, Texas)
ASSIGNEE(S) The University of Akron (Akron, Ohio)
INVENTOR(S) Joseph Kennedy (Akron, Ohio);  Yongmoon Kwon (Copley, Ohio);  Subramanyam Ummadisetty (Longview, Texas)
ABSTRACT The present invention generally relates to alcohol-terminated polyisobutylene (PIB) compounds, and to a process for making such compounds. In one embodiment, the present invention relates to primary alcohol-terminated polyisobutylene compounds, and to a process for making such compounds. In still another embodiment, the present invention relates to polyisobutylene compounds that can be used to synthesize polyurethanes, to polyurethane compounds made via the use of such polyisobutylene compounds, and to processes for making such compounds. In yet another embodiment, the present invention relates to primary alcohol-terminated polyisobutylene compounds having two or more primary alcohol termini and to a process for making such compounds. In yet another embodiment, the present invention relates to primary terminated polyisobutylene compounds having two or more primary termini selected from amine groups or methacrylate group.
FILED Tuesday, October 31, 2017
APPL NO 15/798542
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/00 (20130101) Original (OR) Class
C08F 8/06 (20130101)
C08F 8/12 (20130101)
C08F 8/32 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/6204 (20130101)
C08G 18/7671 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10005880 Nomura et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Christopher T. Nomura (Syracuse, New York);  Atahualpa Pinto (Syracuse, New York)
ABSTRACT Methods and systems for producing prescribed unit size azido-poly(3-hydroxyalkanoate) (azido-PHA) polymers and copolymers are provided. The methods and systems can employ recombinant bacteria that are not native producers of PHA or lack enzymes to degrade PHA once synthesized, metabolize short to long chain fatty acids without induction, and express an (R)-specific enoyl-CoA hydratase and a PHA synthase, the (R)-specific enoyl-CoA hydratase and PHA synthase having wide substrate specificities. The recombinant bacteria are fed at least one ω-azidofatty acid substrate that is equal in carbon length to the prescribed or desired unit size of an azido-PHA polymer to be produced. Azido-PHA polymers or azido-PHA co-polymers can be conjugated via copper-catalyzed alkyne-azide cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions. The prescribed unit size conjugated azido-PHA polymer or orthogonally conjugated azido-PHA co-polymer that is produced is then isolated and/or purified.
FILED Monday, November 16, 2015
APPL NO 14/942529
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/06 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101)
C12N 9/1029 (20130101)
C12N 15/52 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/625 (20130101)
C12P 13/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006033 Liao et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) James C. Liao (Los Angeles, California);  Igor Bogorad (Tarzana, California)
ABSTRACT Provided are microorganisms that catalyze the synthesis of chemicals and biochemicals from a methanol, methane and/or formaldehyde. Also provided are methods of generating such organisms and methods of synthesizing chemicals and biochemicals using such organisms.
FILED Monday, September 14, 2015
APPL NO 14/853946
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101)
C12N 9/1022 (20130101)
C12N 15/52 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/06 (20130101)
C12P 7/16 (20130101)

Enzymes
C12Y 202/01003 (20130101)
C12Y 401/02009 (20130101)
C12Y 401/02022 (20130101)
C12Y 401/02043 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)
Y02E 50/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006039 Benning et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Christoph Benning (East Lansing, Michigan);   Sanjaya (East Lansing, Michigan);  Changcheng Xu (East Lansing, Michigan)
ABSTRACT The present invention relates to compositions and methods for providing RNA interference (RNAi) vectors comprising trigalactosyldiacylglycerol (tgd) biosynthesis enzyme constructs for increasing oil content of plants. Further, the use of tgd RNAi silencing vectors in combination with co-expression of heterologous oil regulating transcription factors, such as WRINKLED1, are contemplated to overcome the reduced growth and variable levels of embryonic lethality in plants with reduced TGD protein. Additionally, plants having reduced APS1, a gene encoding a major catalytic isoform of the small subunit of AGPase (AGP(−) plants), co-expressing a heterologous oil modulating transcription factor are contemplated for use in combination with plants having reduced TGD. Oil harvested from vegetative tissues of plants comprising vectors and genes of the present invention is contemplated for use in biofuel and biodiesel products.
FILED Friday, October 04, 2013
APPL NO 14/046504
ART UNIT 1662 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101)
C12N 9/1241 (20130101)
C12N 15/8218 (20130101)
C12N 15/8247 (20130101) Original (OR) Class

Enzymes
C12Y 207/07027 (20130101)
C12Y 306/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006051 Boeke et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) New York University (New York, New York);  Johns Hopkins University (, None)
ASSIGNEE(S) New York University (New York, New York);  Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Jef Boeke (New York, New York);  Leslie Mitchell (New York, New York);  Yizhi Cai (Edinburgh, United Kingdom);  Neta Agmon (New York, New York)
ABSTRACT Provided are compositions and methods for use in assembling and expressing a plurality of transcription units using, in one aspect, homologous recombination in yeast. Yeast containing the plurality of transcription units, and isolated transcription units, are also provided. Kits for use in making the yeast and the transcript units are further included.
FILED Monday, April 24, 2017
APPL NO 15/495390
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/64 (20130101)
C12N 15/66 (20130101)
C12N 15/81 (20130101)
C12N 15/905 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006085 Corn et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of The University Of California (Oakland, California)
INVENTOR(S) Robert M. Corn (Corona del Mar, California);  Mana Toma (Irvine, California);  Gabriel Loget (Irvine, California);  Han Wai M. Fung (Irvine, California)
ABSTRACT The present invention relates to nanocones and nanomaterials. In one embodiment, the present invention provides a method of fabricating an array of nanostructures on a flexible film, comprising self-assembling a layer of particles on a film, and fabricating an array of nanostructures by etching and/or modifying the film. In another embodiment, the present invention provides a microarray comprising a nanomaterial comprising a film configured for an array of one or more nanocones.
FILED Tuesday, November 04, 2014
APPL NO 14/532861
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/00 (20130101)
C09D 5/006 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6825 (20130101)
C12Q 1/6825 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class
C12Q 1/6883 (20130101)
C12Q 1/6886 (20130101)
C12Q 2563/157 (20130101)
C12Q 2600/178 (20130101)

Optical Elements, Systems, or Apparatus
G02B 17/002 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24479 (20150115)
Y10T 428/24612 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006196 Alqasimi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Ahmad Alqasimi (Tampa, Florida);  Craig Lusk (Lutz, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Ahmad Alqasimi (Tampa, Florida);  Craig Lusk (Lutz, Florida)
ABSTRACT A shape-morphing space frame (SMSF) utilizing the linear bistable compliant crank-slider mechanism (LBCCSM). The frame's initial shape is constructed from a single-layer grid of flexures, rigid links and LBCCSMs. The grid is bent into the space frame's initial cylindrical shape, which can morph because of the inclusion of LBCCSMs in its structure. The design parameters include the frame's initial height, its tessellation pattern (including the unit cell bistable elements' placement), its initial diameter, and the resulting desired shape. The method used in placing the unit cell bistable elements considers the principle stress trajectories. Two different examples of shape-morphing space frames are presented herein, each starting from a cylindrical-shell space frame and morphing, one to a hyperbolic-shell space frame and the other to a spherical-shell space frame, both morphing by applying moments, which shear the cylindrical shell, and forces, which change the cylinder's radius using Poisson's effect.
FILED Wednesday, August 30, 2017
APPL NO 15/691110
ART UNIT 3633 — Static Structures, Supports and Furniture
CURRENT CPC
General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings
E04B 1/1903 (20130101)
E04B 1/3441 (20130101) Original (OR) Class
E04B 1/34384 (20130101)
E04B 2001/1942 (20130101)
E04B 2001/1957 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006874 Charette et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) XRSciences LLC (Carlsbad, California)
ASSIGNEE(S) XRSciences, LLC (Carlsbad, California)
INVENTOR(S) Colin Charette (Carlsbad, California);  Thomas Atwell (Carlsbad, California);  Tom Gibbons (Carlsbad, California);  Jacob Lopp (Carlsbad, California);  Chaur-Ming Shyu (Carlsbad, California);  John Dascomb (Carlsbad, California)
ABSTRACT A process for preparing alternative fuels so that it is acceptable for use in cement plants and other manufacturing processes is detailed. This includes a material analyzer that can detect trace contaminants in alternative fuels. This new analyzer, combined with an associated method of processing the alternative fuels allows users to blend the fuel to ensure that it is acceptable for plant operations.
FILED Friday, May 02, 2014
APPL NO 14/888929
ART UNIT 2884 — Optics
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 5/34 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 5/48 (20130101)
C10L 2290/24 (20130101)
C10L 2290/60 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/12 (20130101)
G01N 23/222 (20130101) Original (OR) Class

Measurement of Nuclear or X-radiation
G01T 3/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006908 Zhong et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Research Foundation for The State University of New York (Binghamton, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Binghamton, New York)
INVENTOR(S) Chuan-Jian Zhong (Endwell, New York);  Hye-Young Park (Seoul, South Korea)
ABSTRACT The present invention is directed toward core-shell nanoparticles, each comprising a ligand-capped metal shell surrounding a plurality of discrete, nonconcentric, metal-containing cores. Methods of making and using these nanoparticles are also disclosed.
FILED Thursday, April 14, 2016
APPL NO 15/099129
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/02 (20130101)

Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields
B03C 1/30 (20130101)

Processes for Applying Fluent Materials to Surfaces, in General
B05D 7/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 25/00 (20130101)
B82Y 40/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/553 (20130101)
G01N 33/54326 (20130101)
G01N 33/54346 (20130101) Original (OR) Class
G01N 33/54353 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2991 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007336 McMurrough
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Christopher D. McMurrough (Arlington, Texas)
ABSTRACT An apparatus, system, and method for a mobile, low-cost headset for 3D point of gaze estimation. A point of gaze apparatus may include an eye tracking camera configured to track the movements of a user's eye and a scene camera configured to create a three-dimensional image and a two-dimensional image in the direction of the user's gaze. The point of gaze apparatus may include an image processing module configured to identify a point of gaze of the user and identify an object located at the user's point of gaze by using information from the eye tracking camera and the scene camera.
FILED Wednesday, September 10, 2014
APPL NO 14/482109
ART UNIT 2482 — Recording and Compression
CURRENT CPC
Electric Digital Data Processing
G06F 3/013 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00604 (20130101)
G06K 9/6211 (20130101)
G06K 9/6212 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007341 Colgate et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) J. Edward Colgate (Evanston, Illinois);  Michael A. Peshkin (Evanston, Illinois);  Xiaowei Dai (Beijing, China PRC);  John Ware (Brookline, Massachusetts);  Nicholas Marchuk (Chicago, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) J. Edward Colgate (Evanston, Illinois);  Michael A. Peshkin (Evanston, Illinois);  Xiaowei Dai (Beijing, China PRC);  John Ware (Brookline, Massachusetts);  Nicholas Marchuk (Chicago, Illinois)
ABSTRACT A touch interface device includes a touch surface configured to be engaged by an object, first and second actuator assemblies operably connected to the touch surface, and a controller operably connected with the first and second actuator assemblies. The first actuator assembly displaces the touch surface in one or more lateral directions along the touch surface at a first frequency. The second actuator assembly displaces the touch surface in an angled direction that is one of at least obliquely or perpendicularly angled to the touch surface at a second frequency. The controller operates the first and second actuator assemblies so that the touch surface varies in engagement with the object to impart a force on the object that is along the touch surface.
FILED Wednesday, June 20, 2012
APPL NO 13/528024
ART UNIT 2696 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 1/1643 (20130101)
G06F 3/016 (20130101) Original (OR) Class
G06F 3/041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007592 Bagchi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Saurabh Bagchi (West Lafayette, Indiana);  Matthew Edward Tan Creti (Lafayette, Indiana);  Vinaitheerthan Sundaram (West Lafayette, Indiana);  Patrick Eugster (West Layfayette, Indiana)
ABSTRACT An embedded device includes a processor executing instructions from module(s) in a code memory. The instructions specify: reading data from two non-deterministic registers (NDRs) of different types, compressing the data using respective, different compression algorithms, and storing the compressed data in a nonvolatile medium. A method of enabling debug tracing in a computer program product (CPP) includes locating instructions in the CPP that read NDRs, determining types of the NDRs, and adding instruction(s) to the CPP to compress the values read using compression algorithms corresponding to the respective NDR types. An emulator in a computer-readable medium receives emulation-target instructions (ETIs) and compressed NDR data, and emulates an execution sequence of the ETIs by determining NDR-reading instructions, determining a type of the NDR read by each, decompressing a portion of the NDR data using a type-specific decompressor, and updating emulated-machine state based on the decompressed portion.
FILED Friday, October 03, 2014
APPL NO 15/031230
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 9/3865 (20130101)
G06F 9/30098 (20130101)
G06F 11/362 (20130101)
G06F 11/364 (20130101)
G06F 11/366 (20130101) Original (OR) Class

Coding; Decoding; Code Conversion in General
H03M 7/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007679 Guo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) The Research Foundation for The State University of New York (Binghamton, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Binghamton, New York)
INVENTOR(S) Zhen Guo (Warrington, Pennsylvania);  Zhongfei Zhang (Vestal, New York)
ABSTRACT Multimodal data mining in a multimedia database is addressed as a structured prediction problem, wherein mapping from input to the structured and interdependent output variables is learned. A system and method for multimodal data mining is provided, comprising defining a multimodal data set comprising image information; representing image information of a data object as a set of feature vectors in a feature space; clustering in the feature space to group similar features; associating a non-image representation with a respective image data object based on the clustering; determining a joint feature representation of a respective data object as a mathematical weighted combination of a set of components of the joint feature representation; optimizing a weighting for a plurality of components of the mathematical weighted combination with respect to a prediction error between a predicted classification and a training classification; and employing the mathematical weighted combination for automatically classifying a new data object.
FILED Monday, December 29, 2014
APPL NO 14/583893
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 17/10 (20130101)
G06F 17/30 (20130101)
G06F 17/30017 (20130101)
G06F 17/30256 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/62 (20130101)
G06K 9/629 (20130101)
G06K 9/6218 (20130101)
G06K 9/6269 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007986 Wu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  QUANTA COMPUTER, INC. (Tao Yuan Shein, Taiwan)
INVENTOR(S) Hao-yu Wu (Cambridge, Massachusetts);  Michael Rubinstein (Somerville, Massachusetts);  Eugene Inghaw Shih (Brookline, Massachusetts);  John V. Guttag (Lexington, Massachusetts);  Frederic Durand (Somerville, Massachusetts);  William T. Freeman (Acton, Massachusetts);  Neal Wadhwa (Mountain View, California)
ABSTRACT In an embodiment, a method converts two images to a transform representation in a transform domain. For each spatial position, the method examines coefficients representing a neighborhood of the spatial position that is spatially the same across each of the two images. The method calculates a first vector in the transform domain based on first coefficients representing the spatial position, the first vector representing change from a first to second image of the two images describing deformation. The method modifies the first vector to create a second vector in the transform domain representing amplified movement at the spatial position between the first and second images. The method calculates second coefficients based on the second vector of the transform domain. From the second coefficients, the method generates an output image showing motion amplified according to the second vector for each spatial position between the first and second images.
FILED Friday, September 29, 2017
APPL NO 15/721375
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/0016 (20130101)
G06T 7/254 (20170101)
G06T 7/262 (20170101)
G06T 2207/20016 (20130101)
G06T 2207/30076 (20130101)
G06T 2207/30088 (20130101)
G06T 2207/30104 (20130101)
G06T 2207/30201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008007 Taubin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Brown University (Providence, Rhode Island)
ASSIGNEE(S) Brown University (Providence, Rhode Island)
INVENTOR(S) Gabriel Taubin (Providence, Rhode Island);  Daniel Moreno (Providence, Rhode Island)
ABSTRACT A method that estimates the coordinates of the calibration points in the projector image plane using local homographies obtained from the imaging camera. First, a dense set of correspondences between projector and camera pixels is found by projecting onto the calibration object an identical pattern sequence as the one later projected when scanning the target, reusing most of the software components written for the scanning application. Second, the set of correspondences is used to compute a group of local homographies that allow projection back of any of the points in the calibration object onto the projector image plane with sub-pixel precision. In the end, the data projector is then calibrated as a normal camera.
FILED Thursday, September 19, 2013
APPL NO 14/031711
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/80 (20170101) Original (OR) Class
G06T 7/85 (20170101)
G06T 7/521 (20170101)
G06T 2207/30244 (20130101)

Pictorial Communication, e.g Television
H04N 13/0246 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008035 Redden et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Blue River Technology Inc. (Sunnyvale, California)
ASSIGNEE(S) Blue River Technology Inc. (Sunnyvale, California)
INVENTOR(S) Lee Kamp Redden (Stanford, California);  Nicholas Apostoloff (Sunnyvale, California)
ABSTRACT A technique for generating virtual models of plants in a field is described. Generally, this includes recording images of plants in-situ; generating point clouds from the images; generating skeleton segments from the point cloud; classifying a subset of skeleton segments as unique plant features using the images; and growing plant skeletons from skeleton segments classified as unique plant feature. The technique may be used to generate a virtual model of a single, real plant, a portion of a real plant field, and/or the entirety of the real plant field. The virtual model can be analyzed to determine or estimate a variety of individual plant or plant population parameters, which in turn can be used to identify potential treatments or thinning practices, or predict future values for yield, plant uniformity, or any other parameter can be determined from the projected results based on the virtual model.
FILED Wednesday, May 18, 2016
APPL NO 15/157997
ART UNIT 2617 — Recording and Compression
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0032 (20130101)
G06T 7/0044 (20130101)
G06T 7/0081 (20130101)
G06T 9/00 (20130101)
G06T 15/08 (20130101)
G06T 17/05 (20130101) Original (OR) Class
G06T 17/20 (20130101)
G06T 2207/20144 (20130101)
G06T 2210/56 (20130101)
G06T 2219/2008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008129 Reiley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
NSF Graduate Research Fellowship Program (GRFP)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Carol E. Reiley (Baltimore, Maryland);  Gregory D. Hager (Baltimore, Maryland);  Balakrishnan Varadarajan (Baltimore, Maryland);  Sanjeev Pralhad Khudanpur (Baltimore, Maryland);  Rajesh Kumar (Baltimore, Maryland);  Henry C. Lin (Baltimore, Maryland)
ABSTRACT A system quantifying clinical skill of a user, comprising: collecting data relating to a surgical task done by a user using a surgical device; comparing the data for the surgical task to other data for another similar surgical task; quantifying the clinical skill of the user based on the comparing of the data for the surgical task to the other data for the other similar surgical task; outputting the clinical skill of the user.
FILED Wednesday, April 19, 2017
APPL NO 15/491640
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 5/02 (20130101)
G09B 23/28 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008248 Buhrman et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Robert A Buhrman (Ithaca, New York);  Minh-hai Nguyen (Ithaca, New York);  Chi-feng Pai (Ithaca, New York);  Daniel C Ralph (Ithaca, New York)
ABSTRACT Devices or circuits based on spin torque transfer (STT) and Spin Hall effect are disclosed by using a spin Hall effect (SHE) metal layer coupled to a magnetic free layer for various applications. The efficiency or strength of the STT effect based on this combination of SHE and STT can be enhanced by an interface modification between the SHE metal layer and the magnetic free layer or by modifying or engineering the SHE metal layer by doping the SHE metal with certain impurities or other means.
FILED Friday, July 17, 2015
APPL NO 15/327017
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101) Original (OR) Class
G11C 11/1673 (20130101)
G11C 11/1675 (20130101)
G11C 11/1697 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/222 (20130101)
H01L 43/04 (20130101)
H01L 43/08 (20130101)
H01L 43/10 (20130101)
H01L 43/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008375 Ouyang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Zheng Ouyang (West Lafayette, Indiana);  Yue Ren (West Lafayette, Indiana);  Jiangjiang Liu (West Lafayette, Indiana);  Linfan Li (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems for analyzing a sample and methods of use thereof. In certain aspects, the invention provides systems that include an ionization probe and a mass analyzer. The probe includes a hollow body that has a distal tip. The probe also includes a substrate that is at least partially disposed within the body and positioned prior to the distal tip so that sample extracted from the substrate flows into the body prior to exiting the distal tip. The probe also includes an electrode that operably interacts with sample extracted from the substrate.
FILED Friday, January 10, 2014
APPL NO 14/426591
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/167 (20130101)
H01J 49/0409 (20130101) Original (OR) Class
H01J 49/0431 (20130101)
H01J 49/4205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008443 Tai et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Yu-Chong Tai (Pasadena, California);  Han-Chieh Chang (Pasadena, California)
ABSTRACT The invention provides chip packaging and processes for the assembly of retinal prosthesis devices. Advantageously, photo-patternable adhesive or epoxy such as photoresist is used as glue to attach a chip to the targeted thin-film (e.g., parylene) substrate so that the chip is used as an attachment to prevent delamination.
FILED Friday, August 28, 2015
APPL NO 14/838788
ART UNIT 3738 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0543 (20130101)
A61N 1/36046 (20130101)
A61N 5/0622 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02002 (20130101)
H01L 21/4846 (20130101)
H01L 23/10 (20130101)
H01L 23/055 (20130101)
H01L 23/4985 (20130101) Original (OR) Class
H01L 23/49894 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008683 Lee et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Byoung Hoon Lee (Goleta, California);  Alan J. Heeger (Santa Barbara, California)
ABSTRACT An organic device, including semiconducting polymers processed from a solution cast on one or more dielectric layers on a substrate; and electrical contacts to the semiconducting polymers, wherein the substrate and the one or more dielectric layers are flexible and the semiconducting polymers are aligned. The one or more dielectric layers can increase mobility of the semiconducting polymers and/or alignment of the semiconducting polymers with one or more of the nanogrooves in the dielectric layers.
FILED Monday, July 18, 2016
APPL NO 15/213029
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/005 (20130101)
B05D 1/18 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0002 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0012 (20130101)
H01L 51/0036 (20130101)
H01L 51/0097 (20130101) Original (OR) Class
H01L 51/0558 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008962 Khizroev et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Sakhrat Khizroev (Miami, Florida);  Rakesh Guduru (Miami, Florida)
ASSIGNEE(S) The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S) Sakhrat Khizroev (Miami, Florida);  Rakesh Guduru (Miami, Florida)
ABSTRACT A compact magnetic-based battery device that offers energy, a large number of cycles, a long storage time, and a short charging time is provided. The rechargeable battery device can include a first magnetic layer, a second magnetic layer, a dielectric layer disposed between the first magnetic layer and the second magnetic layer, and a plurality of high anisotropic magnetic nanoparticles embedded into the dielectric layer.
FILED Thursday, August 31, 2017
APPL NO 15/692423
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/06 (20130101)
H01L 41/20 (20130101)
H01L 41/125 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/186 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009103 Vahala et al.
FUNDED BY
Department of Commerce (DOC)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
INVENTOR(S) Kerry Vahala (Pasadena, California);  Scott Diddams (Boulder, Colorado);  Jiang Li (Pasadena, California);  Xu Yi (Pasadena, California);  Hansuek Lee (Pasadena, California)
ABSTRACT A microwave-frequency source at frequency fM comprises: a dual optical-frequency reference source, an electro-optic sideband generator, an optical bandpass filter, an optical detector, a reference oscillator, an electrical circuit, and a voltage-controlled oscillator (VCO). The sideband generator modulates dual optical reference signals at v2 and v1 to generate sideband signals at v1±n1fM and v2±n2fM. The bandpass filter transmits sideband signals at v1+N1fM and v2−N2fM. The optical detector generates a beat note at (v2−N2fM)−(v1+N1fM). The beat note and a reference oscillator signal are processed by the circuit to generate a loop-filtered error signal to input to the VCO. Output of the VCO at fM drives the sideband generator and forms the microwave-frequency output signal. The resultant frequency division results in reduced phase noise on the microwave-frequency signal.
FILED Thursday, August 11, 2016
APPL NO 15/235075
ART UNIT 2637 — Optical Communications
CURRENT CPC
Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 17/00 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/08 (20130101)
H03L 7/16 (20130101)

Transmission
H04B 10/503 (20130101)
H04B 10/2504 (20130101)
H04B 10/2507 (20130101) Original (OR) Class
H04B 10/2575 (20130101)
H04B 2210/006 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0075 (20130101)
H04L 7/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009171 Shrimpton et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Portland State University (Portland, Oregon)
ASSIGNEE(S) Portland State University (Portland, Oregon)
INVENTOR(S) Thomas E. Shrimpton (Portland, Oregon);  Robert S. Terashima (Portland, Oregon)
ABSTRACT Innovations in the construction and use of variable-input-length tweakable ciphers (“VILTCs”). In some cases, a VILTC uses an initialization vector that is protected from exposure outside an encryption/decryption system in order to provide enhanced security with efficient performance. For example, a system for encryption and/or decryption includes two fixed-input-length tweakable block ciphers (“FIL TBCs”) and a VILTC. The first FIL TBC is adapted to produce a fixed-length initialization vector. The VILTC is adapted to produce a variable-length output string using the fixed-length initialization vector as a tweak. The second FIL TBC is adapted to produce a fixed-length output string. In this way, the first FIL TBC and the second FIL TBC protect the fixed-length initialization vector from exposure outside the system. In other cases, a VILTC is used for a reliable and efficient implementation of authenticated encryption/decryption with associated data.
FILED Wednesday, December 28, 2016
APPL NO 15/393062
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 12/1408 (20130101)
G06F 2212/402 (20130101)
G06F 2212/1052 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0625 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 10004174 Kornecki et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Ted S. Kornecki (Auburn, Alabama);  Corey M. Kichler (Auburn, Alabama)
ABSTRACT The transplanter is designed to harness power from a walk-behind tractor to help small farmers transplant (among other things) seedling vegetables. As a farmer guides the walk-behind tractor, a movable feeder tube assembly comprising a plurality of feeder tubes moves latterly back and forth. When a feeder tube aligns with a pivotable transfer tube, a seedling in the feeder tube is deposited in the transfer tube so that the seedling descends down the transfer tube into a furrow for planting. The transfer tube then pivots so that a kicker panel on the bottom of the transfer tube pushes the seedling rearwardly and thereby helps to enable the seedling to remain vertical.
FILED Thursday, September 29, 2016
APPL NO 15/280605
ART UNIT 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Planting; Sowing; Fertilising
A01C 5/062 (20130101)
A01C 5/064 (20130101)
A01C 5/068 (20130101)
A01C 11/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10004797 Harris et al.
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Harrisvaccines, Inc. (Ames, Iowa)
ASSIGNEE(S) Harrisvaccines, Inc. (Ames, Iowa)
INVENTOR(S) Delbert Linn Harris (Ames, Iowa);  Matthew Erdman (Ankeny, Iowa);  Kurt Iver Kamrud (Apex, North Carolina);  Jonathan Fowler Smith (San Diego, California);  John Dustin Loy (Lincoln, Nebraska);  Lyric Colleen Bartholomay (Ames, Iowa);  Ed Scura (Potomac, Maryland)
ABSTRACT A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained from a biological sample from an animal exposed to the microorganism, a protective molecule is prepared based on the nucleic acid molecule of interest or fragment thereof, and administered to an animal which has been or is as risk of being exposed to the microorganism. A protective response to the biotype of the microorganism is obtained in the animal.
FILED Tuesday, October 23, 2012
APPL NO 13/657895
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/0013 (20130101)
A61K 39/135 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/552 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/111 (20130101)
C12N 15/1131 (20130101)
C12N 2310/14 (20130101)
C12N 2310/111 (20130101)
C12N 2320/32 (20130101)
C12N 2710/18022 (20130101)
C12N 2710/18034 (20130101)
C12N 2720/00022 (20130101)
C12N 2720/00034 (20130101)
C12N 2720/12143 (20130101)
C12N 2760/16034 (20130101)
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
C12N 2770/10022 (20130101)
C12N 2770/10034 (20130101)
C12N 2770/32122 (20130101)
C12N 2770/32134 (20130101)
C12N 2770/36143 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/701 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006019 Lo et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Yangming Martin Lo (Ashton, Maryland);  Hong Fu (Fujian, Switzerland)
ABSTRACT A novel method for processing soluble plant leaf proteins is described. While leaf proteins are considered potentially the most abundant source of protein in nature, the lack of efficient processing techniques for leaf proteins has limited their commercial use. The method described in this patent provides a means of extracting and purifying leaf proteins from plants which is suitable for leaf protein production on an industrial scale.
FILED Wednesday, December 13, 2017
APPL NO 15/840857
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 36/81 (20130101)

Separation
B01D 9/0059 (20130101)
B01D 11/0288 (20130101)

Peptides
C07K 1/30 (20130101)
C07K 1/36 (20130101)
C07K 1/145 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101) Original (OR) Class

Enzymes
C12Y 401/01039 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006039 Benning et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Christoph Benning (East Lansing, Michigan);   Sanjaya (East Lansing, Michigan);  Changcheng Xu (East Lansing, Michigan)
ABSTRACT The present invention relates to compositions and methods for providing RNA interference (RNAi) vectors comprising trigalactosyldiacylglycerol (tgd) biosynthesis enzyme constructs for increasing oil content of plants. Further, the use of tgd RNAi silencing vectors in combination with co-expression of heterologous oil regulating transcription factors, such as WRINKLED1, are contemplated to overcome the reduced growth and variable levels of embryonic lethality in plants with reduced TGD protein. Additionally, plants having reduced APS1, a gene encoding a major catalytic isoform of the small subunit of AGPase (AGP(−) plants), co-expressing a heterologous oil modulating transcription factor are contemplated for use in combination with plants having reduced TGD. Oil harvested from vegetative tissues of plants comprising vectors and genes of the present invention is contemplated for use in biofuel and biodiesel products.
FILED Friday, October 04, 2013
APPL NO 14/046504
ART UNIT 1662 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101)
C12N 9/1241 (20130101)
C12N 15/8218 (20130101)
C12N 15/8247 (20130101) Original (OR) Class

Enzymes
C12Y 207/07027 (20130101)
C12Y 306/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006166 Zhu et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) JunYong Zhu (Madison, Wisconsin);  Liheng Chen (Madison, Wisconsin);  Rolland Gleisner (Jefferson, Wisconsin)
ABSTRACT Methods for integrating the production of carboxylated CNCs and carboxylated CNFs from cellulose are provided. Carboxylated CNCs, carboxylated cellulosic solid residues (CSRs) in the form of cellulose fibers (CF) and/or cellulose microfibrils (CMFs), and carboxylated CNFs fabricated using the methods are also provided. The methods are based on the acid hydrolysis of a cellulosic material using weak solid organic acids to produce carboxylated CNCs and CNFs with thermal stabilities that are higher than the thermal stabilities of the cellulosic materials from which they are derived.
FILED Friday, February 05, 2016
APPL NO 15/017229
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Polysaccharides; Derivatives Thereof
C08B 15/08 (20130101)

Fibrous Raw Materials or Their Mechanical Treatment
D21B 1/06 (20130101)
D21B 1/021 (20130101) Original (OR) Class

Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor
D21C 9/005 (20130101)
D21C 9/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 10005818 Krishna et al.
FUNDED BY
Department of Commerce (DOC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) REALTA HOLDINGS, LLC (Norfolk, Virginia)
ASSIGNEE(S) REALTA HOLDINGS, LLC (Norfolk, Virginia)
INVENTOR(S) Neel K. Krishna (Norfolk, Virginia);  Kenji Cunnion (Norfolk, Virginia)
ABSTRACT The present invention provides synthetic peptide compounds and uses thereof for therapy and diagnostics of complement-mediated diseases, such as inflammatory diseases, autoimmune diseases, and microbial and bacterial infections; and non-complement-mediated diseases, such cystic fibrosis and various acute diseases. The invention is directed to modifications of a synthetic peptide of 15 amino acids from the Polar Assortant (PA) peptide, which is a scrambled peptide derived from human Astrovirus protein. In some embodiments, the invention is directed to peptide compounds that are peptide mimetics, peptide analogs and/or synthetic derivatives of PA (e.g., sarcosine derivatives) having, for example, internal peptide substitutions, and modifications, including PEGylation at the N-terminus and C-terminus. The invention further provides methods of selecting at least one synthetic peptide for treating various conditions.
FILED Friday, June 24, 2016
APPL NO 15/192934
ART UNIT 1675 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/02 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/03 (20130101)
A61K 38/162 (20130101)
A61K 38/1725 (20130101)

Peptides
C07K 7/08 (20130101)
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/16611 (20130101)
C12N 2770/12022 (20130101)
C12N 2770/12033 (20130101)
C12N 2770/12071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10007885 Gorshkov et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) The United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERCA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
INVENTOR(S) Alexey V. Gorshkov (Rockville, Maryland);  Michael S. Foss-Feig (Baltimore, Maryland);  Zachary Eldredge (Adelphi, Maryland);  Steven L. Rolston (Derwood, Maryland)
ABSTRACT Determining a modal amplitude of an inhomogeneous field includes: preparing an initial entangled state of a quantum sensor; subjecting the quantum sensor to the inhomogeneous field of the analyte; subjecting a first qudit sensor of the quantum sensor to a first perturbation pulse; receiving the first perturbation pulse by the first qudit sensor to prepare a first intermediate entangled state of the quantum sensor, the first intermediate entangled state comprising a first intermediate linear superposition; changing the initial linear superposition to the first intermediate linear superposition in response to receiving the first perturbation pulse by the quantum sensor; and determining a final entangled state of the quantum sensor after applying the first perturbation pulse to determine the modal amplitude of the inhomogeneous field of the analyte.
FILED Friday, July 14, 2017
APPL NO 15/650216
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/008 (20130101)
G01N 29/4472 (20130101)
G01N 35/0098 (20130101)

Electric Digital Data Processing
G06F 17/10 (20130101)

Computer Systems Based on Specific Computational Models
G06N 99/002 (20130101) Original (OR) Class

Transmission
H04B 10/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10009103 Vahala et al.
FUNDED BY
Department of Commerce (DOC)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia)
INVENTOR(S) Kerry Vahala (Pasadena, California);  Scott Diddams (Boulder, Colorado);  Jiang Li (Pasadena, California);  Xu Yi (Pasadena, California);  Hansuek Lee (Pasadena, California)
ABSTRACT A microwave-frequency source at frequency fM comprises: a dual optical-frequency reference source, an electro-optic sideband generator, an optical bandpass filter, an optical detector, a reference oscillator, an electrical circuit, and a voltage-controlled oscillator (VCO). The sideband generator modulates dual optical reference signals at v2 and v1 to generate sideband signals at v1±n1fM and v2±n2fM. The bandpass filter transmits sideband signals at v1+N1fM and v2−N2fM. The optical detector generates a beat note at (v2−N2fM)−(v1+N1fM). The beat note and a reference oscillator signal are processed by the circuit to generate a loop-filtered error signal to input to the VCO. Output of the VCO at fM drives the sideband generator and forms the microwave-frequency output signal. The resultant frequency division results in reduced phase noise on the microwave-frequency signal.
FILED Thursday, August 11, 2016
APPL NO 15/235075
ART UNIT 2637 — Optical Communications
CURRENT CPC
Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 17/00 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/08 (20130101)
H03L 7/16 (20130101)

Transmission
H04B 10/503 (20130101)
H04B 10/2504 (20130101)
H04B 10/2507 (20130101) Original (OR) Class
H04B 10/2575 (20130101)
H04B 2210/006 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0075 (20130101)
H04L 7/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10005668 Hung et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Ching-cheh Hung (Westlake, Ohio);  Janet B. Hurst (Columbia Station, Ohio)
ABSTRACT Methods that facilitate exfoliation of hexagonal boron nitride (hBN), exfoliated hBN, and associated intermediate products are disclosed. Such a method can include the acts of mixing a sample of hBN with an activation agent (e.g., NaF, etc.) and a selected set of chemicals (e.g., a metal chloride) and intercalating the set of chemicals into the hBN to obtain intercalated hBN. Additionally, such a method can include the acts of hydrating the set of chemicals (i.e., the intercalates), and converting the set of chemicals to a set of oxide nanoparticles when exfoliating the intercalated hBN. The exfoliated hBN can be washed (e.g., with HCl, etc.) to remove remaining nanoparticles.
FILED Friday, January 17, 2014
APPL NO 14/158080
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 21/064 (20130101) Original (OR) Class
C01B 21/0648 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006291 London et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Astra Space, Inc. (San Francisco, California)
ASSIGNEE(S) ASTRA SPACE, INC. (San Francisco, California)
INVENTOR(S) Adam P. London (San Francisco, California);  Lloyd J. Droppers (Sunnyvale, California);  Matthew K. Lehman (Santa Cruz, California);  Amitav Mehra (Arlington, Virginia)
ABSTRACT A small scale, high speed turbomachine is described, as well as a process for manufacturing the turbomachine. The turbomachine is manufactured by diffusion bonding stacked sheets of metal foil, each of which has been pre-formed to correspond to a cross section of the turbomachine structure. The turbomachines include rotating elements as well as static structures. Using this process, turbomachines may be manufactured with rotating elements that have outer diameters of less than four inches in size, and/or blading heights of less than 0.1 inches. The rotating elements of the turbomachines are capable of rotating at speeds in excess of 150 feet per second. In addition, cooling features may be added internally to blading to facilitate cooling in high temperature operations.
FILED Friday, February 06, 2015
APPL NO 14/616048
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 2700/12 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/028 (20130101) Original (OR) Class
F01D 5/048 (20130101)
F01D 5/147 (20130101)
F01D 9/045 (20130101)

Non-positive-displacement Pumps
F04D 13/043 (20130101)
F04D 29/242 (20130101)
F04D 29/669 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/30 (20130101)
F05D 2230/14 (20130101)
F05D 2230/50 (20130101)
F05D 2250/82 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/4932 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006886 Campbell Leckey
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Cara A. Campbell Leckey (Yorktown, Virginia)
ABSTRACT A method of detecting internal defects in composites or other multilayer materials includes generating a wavefield on a surface of the material. Wavefield data is collected from the wavefield on the surface, and the measured wavefield data is processed to provide measured energy data. The method may include generating simulated or predicted energy data for the multilayer material that is compared to the simulated energy data to determine if the multilayer material has internal defects or damage below the surface. The method can be utilized to detect and/or quantify damage or other defects that are “hidden” by damage that is closer to the surface of the material.
FILED Tuesday, May 12, 2015
APPL NO 14/709887
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/043 (20130101) Original (OR) Class
G01N 29/2437 (20130101)
G01N 29/4436 (20130101)
G01N 2291/0231 (20130101)
G01N 2291/2694 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10004797 Harris et al.
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Harrisvaccines, Inc. (Ames, Iowa)
ASSIGNEE(S) Harrisvaccines, Inc. (Ames, Iowa)
INVENTOR(S) Delbert Linn Harris (Ames, Iowa);  Matthew Erdman (Ankeny, Iowa);  Kurt Iver Kamrud (Apex, North Carolina);  Jonathan Fowler Smith (San Diego, California);  John Dustin Loy (Lincoln, Nebraska);  Lyric Colleen Bartholomay (Ames, Iowa);  Ed Scura (Potomac, Maryland)
ABSTRACT A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained from a biological sample from an animal exposed to the microorganism, a protective molecule is prepared based on the nucleic acid molecule of interest or fragment thereof, and administered to an animal which has been or is as risk of being exposed to the microorganism. A protective response to the biotype of the microorganism is obtained in the animal.
FILED Tuesday, October 23, 2012
APPL NO 13/657895
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/0013 (20130101)
A61K 39/135 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/552 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/111 (20130101)
C12N 15/1131 (20130101)
C12N 2310/14 (20130101)
C12N 2310/111 (20130101)
C12N 2320/32 (20130101)
C12N 2710/18022 (20130101)
C12N 2710/18034 (20130101)
C12N 2720/00022 (20130101)
C12N 2720/00034 (20130101)
C12N 2720/12143 (20130101)
C12N 2760/16034 (20130101)
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
C12N 2770/10022 (20130101)
C12N 2770/10034 (20130101)
C12N 2770/32122 (20130101)
C12N 2770/32134 (20130101)
C12N 2770/36143 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/701 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006291 London et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Astra Space, Inc. (San Francisco, California)
ASSIGNEE(S) ASTRA SPACE, INC. (San Francisco, California)
INVENTOR(S) Adam P. London (San Francisco, California);  Lloyd J. Droppers (Sunnyvale, California);  Matthew K. Lehman (Santa Cruz, California);  Amitav Mehra (Arlington, Virginia)
ABSTRACT A small scale, high speed turbomachine is described, as well as a process for manufacturing the turbomachine. The turbomachine is manufactured by diffusion bonding stacked sheets of metal foil, each of which has been pre-formed to correspond to a cross section of the turbomachine structure. The turbomachines include rotating elements as well as static structures. Using this process, turbomachines may be manufactured with rotating elements that have outer diameters of less than four inches in size, and/or blading heights of less than 0.1 inches. The rotating elements of the turbomachines are capable of rotating at speeds in excess of 150 feet per second. In addition, cooling features may be added internally to blading to facilitate cooling in high temperature operations.
FILED Friday, February 06, 2015
APPL NO 14/616048
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 2700/12 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/028 (20130101) Original (OR) Class
F01D 5/048 (20130101)
F01D 5/147 (20130101)
F01D 9/045 (20130101)

Non-positive-displacement Pumps
F04D 13/043 (20130101)
F04D 29/242 (20130101)
F04D 29/669 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/30 (20130101)
F05D 2230/14 (20130101)
F05D 2230/50 (20130101)
F05D 2250/82 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/4932 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10008035 Redden et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Blue River Technology Inc. (Sunnyvale, California)
ASSIGNEE(S) Blue River Technology Inc. (Sunnyvale, California)
INVENTOR(S) Lee Kamp Redden (Stanford, California);  Nicholas Apostoloff (Sunnyvale, California)
ABSTRACT A technique for generating virtual models of plants in a field is described. Generally, this includes recording images of plants in-situ; generating point clouds from the images; generating skeleton segments from the point cloud; classifying a subset of skeleton segments as unique plant features using the images; and growing plant skeletons from skeleton segments classified as unique plant feature. The technique may be used to generate a virtual model of a single, real plant, a portion of a real plant field, and/or the entirety of the real plant field. The virtual model can be analyzed to determine or estimate a variety of individual plant or plant population parameters, which in turn can be used to identify potential treatments or thinning practices, or predict future values for yield, plant uniformity, or any other parameter can be determined from the projected results based on the virtual model.
FILED Wednesday, May 18, 2016
APPL NO 15/157997
ART UNIT 2617 — Recording and Compression
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0032 (20130101)
G06T 7/0044 (20130101)
G06T 7/0081 (20130101)
G06T 9/00 (20130101)
G06T 15/08 (20130101)
G06T 17/05 (20130101) Original (OR) Class
G06T 17/20 (20130101)
G06T 2207/20144 (20130101)
G06T 2210/56 (20130101)
G06T 2219/2008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 10005561 Kiebles et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) GE Aviation Systems LLC (Grand Rapids, Michigan)
ASSIGNEE(S) GE Aviation Systems LLC (Grand Rapids, Michigan)
INVENTOR(S) Steven Louis Kiebles (Grand Rapids, Michigan);  David Michael Lax (Grand Rapids, Michigan);  Otto Y Darias (Grand Rapids, Michigan);  Mark Lawrence Darnell (Grand Rapids, Michigan);  Sean Sanghyun Hwang (Grand Rapids, Michigan);  Christopher Daniel Holbert (Lowell, Michigan);  Harry Kirk Mathews, Jr. (Clifton Park, New York);  Sridhar Adibhatla (Glendale, Ohio);  Jeffrey Russell Bult (Grand Rapids, Michigan);  Thomas Charles Swager (Maineville, Ohio)
ABSTRACT Systems and methods for stabilizing an aircraft in response to a yaw movement are provided. In one embodiment, a method includes detecting a yaw movement of the aircraft. The yaw movement can cause a front portion of the aircraft to move towards a first side of the aircraft. The method can further include, in response to the yaw movement, initiating a trim process resulting in a thrust differential. The trim process can include increasing thrust in one or more engines on the first side of the aircraft and decreasing thrust in one or more engines on a second side of the aircraft. The method can include controlling the trim process based at least in part on a detected yaw movement of the aircraft.
FILED Thursday, June 16, 2016
APPL NO 15/184196
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 15/02 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 31/06 (20130101) Original (OR) Class
B64D 45/00 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0808 (20130101)
G05D 1/0816 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006477 Pantelides et al.
FUNDED BY
Department of Transportation (USDOT)
U.S. State Government
State of Utah
APPLICANT(S) Chris P. Pantelides (Salt Lake City, Utah);  Lawrence D. Reaveley (Draper, Utah);  Clayton A. Burningham (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Chris P. Pantelides (Salt Lake City, Utah);  Lawrence D. Reaveley (Draper, Utah);  Clayton A. Burningham (Salt Lake City, Utah)
ABSTRACT Exemplary sheet and rod attachment apparatus and systems are described for providing composite reinforcement for one or more structures, such that one or more structures can be supported by different reinforcement mechanisms. The sheet and rod attachment apparatus includes an adaptor that couples the sheet to the rod in a manner that minimizes or substantially eliminates localized stress concentrations. The adaptor may include one or more wedge-shaped bodies contoured and configured to attach to at least a portion of a rod of a predetermined size and/or shape. A wedge-shaped body may include an interior surface for engaging the rod, and exterior surfaces extending radially from the interior surface. Example exterior surfaces are configured to engage a reinforcement sheet that extends axially from the rod.
FILED Tuesday, April 12, 2011
APPL NO 13/635608
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 66/721 (20130101)
B29C 66/5326 (20130101)

Structural Elements; Building Materials
E04C 5/07 (20130101)
E04C 5/163 (20130101)

Scaffolding; Forms; Shuttering; Building Implements or Aids, or Their Use; Handling Building Materials on the Site; Repairing, Breaking-up or Other Work on Existing Buildings
E04G 2023/0251 (20130101)

Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 9/02 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 403/3906 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 10004898 Ahmed et al.
FUNDED BY
U.S. State Government
State of New York
APPLICANT(S) Zaghloul Ahmed (Staten Island, New York);  Andrzej Wieraszko (Princeton, New Jersey)
ASSIGNEE(S) THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (New York, New York)
INVENTOR(S) Zaghloul Ahmed (Staten Island, New York);  Andrzej Wieraszko (Princeton, New Jersey)
ABSTRACT A system and method to treat neuromuscular conditions, including spinal cord injury, by what is characterized as dipole (two point) cortico-muscular stimulation. Two-point stimulation, with oppositely charged electrodes, allows pulsed, direct current to pass through the cortico-muscular pathway. The electrodes are placed on nerves, muscles, or a combination of both, that are on opposite sides of the spinal column, forming a current that passes across the spinal column. Further, an active electrode can be placed on the spinal column and a reference electrode can be placed outside the central nervous system. These methods improve functional recovery of the motor pathway.
FILED Wednesday, May 25, 2016
APPL NO 15/163955
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/205 (20130101) Original (OR) Class
A61N 1/0551 (20130101)
A61N 1/36003 (20130101)
A61N 1/36067 (20130101)
A61N 1/36071 (20130101)
A61N 1/36082 (20130101)
A61N 1/36096 (20130101)
A61N 1/36103 (20130101)
A61N 1/36153 (20130101)
A61N 1/36157 (20130101)
A61N 1/36171 (20130101)
A61N 1/36175 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10006477 Pantelides et al.
FUNDED BY
Department of Transportation (USDOT)
U.S. State Government
State of Utah
APPLICANT(S) Chris P. Pantelides (Salt Lake City, Utah);  Lawrence D. Reaveley (Draper, Utah);  Clayton A. Burningham (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Chris P. Pantelides (Salt Lake City, Utah);  Lawrence D. Reaveley (Draper, Utah);  Clayton A. Burningham (Salt Lake City, Utah)
ABSTRACT Exemplary sheet and rod attachment apparatus and systems are described for providing composite reinforcement for one or more structures, such that one or more structures can be supported by different reinforcement mechanisms. The sheet and rod attachment apparatus includes an adaptor that couples the sheet to the rod in a manner that minimizes or substantially eliminates localized stress concentrations. The adaptor may include one or more wedge-shaped bodies contoured and configured to attach to at least a portion of a rod of a predetermined size and/or shape. A wedge-shaped body may include an interior surface for engaging the rod, and exterior surfaces extending radially from the interior surface. Example exterior surfaces are configured to engage a reinforcement sheet that extends axially from the rod.
FILED Tuesday, April 12, 2011
APPL NO 13/635608
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 66/721 (20130101)
B29C 66/5326 (20130101)

Structural Elements; Building Materials
E04C 5/07 (20130101)
E04C 5/163 (20130101)

Scaffolding; Forms; Shuttering; Building Implements or Aids, or Their Use; Handling Building Materials on the Site; Repairing, Breaking-up or Other Work on Existing Buildings
E04G 2023/0251 (20130101)

Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 9/02 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 403/3906 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 10008374 Ouyang et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Zheng Ouyang (West Lafayette, Indiana);  Robert Graham Cooks (West Lafayette, Indiana);  Sandilya Venkata Garimella (West Lafayette, Indiana);  Jason David Harper (Lafayette, Indiana);  Nicholas Alan Charipar (Batavia, Indiana)
ABSTRACT The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.
FILED Tuesday, November 01, 2016
APPL NO 15/340355
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/10 (20130101)
H01J 49/26 (20130101)
H01J 49/0404 (20130101) Original (OR) Class
H01J 49/0409 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 10005719 Ferreira et al.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Eric Ferreira (Athens, Georgia);  Brian J Knight (Gainesville, Florida);  Qiankun Li (Taihe, China PRC)
ABSTRACT A method of preparing ortho-alkenyl and ortho-acetyl benzylic alcohols is disclosed.
FILED Thursday, March 31, 2016
APPL NO 15/088014
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 29/44 (20130101)
C07C 67/347 (20130101)
C07C 231/12 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 491/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US D821679 Mikolajczyk et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Ryszard K. Mikolajczyk (Chicago, Illinois);  Taurris D. Baskerville (Schaumburg, Illinois)
ABSTRACT
FILED Monday, April 24, 2017
APPL NO 29/601564
ART UNIT 2912 — Design
CURRENT CPC
Miscellaneous
D99/29
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 10006071 Baliga et al.
FUNDED BY
APPLICANT(S) Institute for Systems Biology (Seattle, Washington)
ASSIGNEE(S) Institute for System Biology (Seattle, Washington)
INVENTOR(S) Nitin S. Baliga (Seattle, Washington);  Monica V. Orellana (Seattle, Washington);  Kenia Whitehead (Seattle, Washington);  W. Lee Pang (Shoreline, Washington)
ABSTRACT Methods are provided to control the harvesting of desired metabolic byproducts from hypersaline photosynthetic algae. Methods are presented to control secretion of said metabolic products in monocultures and co-cultures after accumulation of byproducts. The metabolic byproduct secretion is controlled by controlling caspase activity.
FILED Tuesday, December 16, 2014
APPL NO 14/572550
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 33/00 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 39/00 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 40/88 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 26, 2018.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180626.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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