FedInvent™ Patents
Patent Details for Tuesday, July 10, 2018
This page was updated on Monday, March 27, 2023 at 05:34 AM GMT
Department of Health and Human Services (HHS)
| US 10015980 | Longo et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Valter D. Longo (Playa del Rey, California); Chia-Wei Cheng (Los Angeles, California); Sebastian Brandhorst (Redondo Beach, California); Min Wei (West Covina, California) |
| ABSTRACT | A method includes a step of identifying a subject in need of diet modification; and administering a first diet to the subject for a first time period. The first diet provides 4.5 to 7 kilocalories per pound of subject for a first day and 3 to 5 kilocalories per pound of subject per day for a second to fifth day of the first diet. The first diet includes less than 30 g of sugar on the first day; less than 20 g of sugar on the second to fifth days; less than 28 g of proteins on the first day; less than 18 g of proteins on days the second to fifth days; 20 to 30 grams of monounsaturated fats on the first day; 10 to 15 grams of monounsaturated fats on the second to fifth days; and between 6 and 10 grams of polyunsaturated fats on the first day. |
| FILED | Tuesday, October 22, 2013 |
| APPL NO | 14/060494 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/37 (20160801) A23L 33/15 (20160801) A23L 33/16 (20160801) A23L 33/17 (20160801) A23L 33/30 (20160801) A23L 33/40 (20160801) Original (OR) Class A23L 33/115 (20160801) A23L 33/155 (20160801) A23L 33/175 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 45/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016130 | Ganesan et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Deepak Ganesan (Amherst, Massachusetts); Benjamin M. Marlin (Amherst, Massachusetts); Addison Mayberry (Fallon, Nevada); Christopher Salthouse (Newton, Massachusetts) |
| ABSTRACT | An improved eye tracker system and methods for detecting eye parameters including eye movement using a pupil center, pupil diameter (i.e., dilation), blink duration, and blink frequency, which may be used to determine a variety of physiological and psychological conditions. The eye tracker system and methods operates at a ten-fold reduction in power usage as compared to current system and methods. Furthermore, eye tracker system and methods allows for a more optimal use in variable light situations such as in the outdoors and does not require active calibration by the user. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257868 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/10 (20130101) A61B 3/032 (20130101) A61B 3/113 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 27/0093 (20130101) G02B 2027/0178 (20130101) G02B 2027/0187 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016156 | Klin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Ami Klin (Atlanta, Georgia); Warren Jones (Decatur, Georgia); Sarah Shultz (Atlanta, Georgia) |
| ABSTRACT | The present systems and methods provide a mechanism to assess viewer behavior, features of stimuli, and the interaction between viewer behavior and stimuli. The systems and methods described herein for quantifying blink response and blink inhibition provide moment-by-moments measurements of viewer engagement by measuring what is or is not engaging enough to warrant viewers' inhibition of blinking. The present disclosure describes measures of visual scanning, eye movements, blink data, and blink timing data to derive a measure of how engaged a person is with what he or she is looking at. Blink-related data as a measure of viewer engagement provides a mechanism for determining the most engaging spatial and temporal aspects of a stimulus. |
| FILED | Wednesday, September 28, 2016 |
| APPL NO | 15/278598 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/0041 (20130101) A61B 3/112 (20130101) A61B 3/113 (20130101) A61B 5/16 (20130101) A61B 5/165 (20130101) Original (OR) Class A61B 5/167 (20130101) A61B 5/168 (20130101) A61B 5/1103 (20130101) A61B 5/4088 (20130101) A61B 5/7275 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016371 | Keselowsky et al. |
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| FUNDED BY |
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| APPLICANT(S) | Benjamin George Keselowsky (Gainesville, Florida); Jamal Lewis (Tallahassee, Florida); Abhinav Acharya (Atlanta, Georgia); Michael J. Clare-Salzler (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (Gainesville, Florida) |
| INVENTOR(S) | Benjamin George Keselowsky (Gainesville, Florida); Jamal Lewis (Tallahassee, Florida); Abhinav Acharya (Atlanta, Georgia); Michael J. Clare-Salzler (Gainesville, Florida) |
| ABSTRACT | The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes. |
| FILED | Monday, October 24, 2011 |
| APPL NO | 13/880778 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) Original (OR) Class A61K 31/59 (20130101) A61K 39/0008 (20130101) A61K 47/6937 (20170801) A61K 2039/6093 (20130101) A61K 2039/55511 (20130101) A61K 2039/55522 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016399 | Pavliv et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cumberland Pharmaceuticals Inc. (Nashville, Tennessee); Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Cumberland Pharmaceuticals Inc. (Nashville, Tennessee); Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Leo Pavliv (Cary, North Carolina); Bryan Voss (Nashville, Tennessee); James West (Nashville, Tennessee); Erica Carrier (Nashville, Tennessee) |
| ABSTRACT | The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by administration of a therapeutically effective amount of ifetroban, or a pharmaceutically acceptable salt thereof. |
| FILED | Tuesday, May 30, 2017 |
| APPL NO | 15/608507 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 31/421 (20130101) Original (OR) Class A61K 31/422 (20130101) Heterocyclic Compounds C07D 263/30 (20130101) C07D 407/04 (20130101) C07D 413/04 (20130101) C07D 493/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016402 | Zon et al. |
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| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Leonard Zon (Wellesley, Massachusetts); Richard M. White (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments of the present invention are directed to methods for treatment of melanoma using an inhibitor of dihydroorotate dehydrogenase (DHODH) and to combination therapies that involve administering to a subject an inhibitor of oncogenic BRAF (e.g. BRAF(V600E)), as well as an inhibitor of dihydroorotate dehydrogenase (DHODH). Assays for identifying compounds useful for the treatment of melanoma are also provided. The methods comprise screening for compounds or agents that inhibit neural crest progenitor formation in a zebra fish model of melanoma. |
| FILED | Monday, June 08, 2015 |
| APPL NO | 14/733498 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/42 (20130101) A61K 31/44 (20130101) Original (OR) Class A61K 31/196 (20130101) A61K 31/381 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016412 | Spiegel et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); Kelly Fitzgerald (New Haven, Connecticut) |
| ABSTRACT | The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) and Toll-like receptor agonist (TLR) through a linker and a multifunctional connector group or molecule. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 15/374272 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class A61K 47/48215 (20130101) A61K 47/48346 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016413 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jia Bei Wang (Ellicott City, Maryland); Sarah Sushchyk (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Jia Bei Wang (Ellicott City, Maryland); Sarah Sushchyk (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed to a method of treating or preventing an addictive behavior in a subject, said method comprising administering to said subject an effective amount of a dopamine antagonist and a opiate receptor antagonist or a composition comprising same. Further provided are pharmaceutical compositions comprising, as active substances, at least one dopamine antagonist and at least one opiate receptor antagonist. |
| FILED | Thursday, September 12, 2013 |
| APPL NO | 14/025434 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/473 (20130101) A61K 31/485 (20130101) Original (OR) Class A61K 31/485 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016414 | Morabito et al. |
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| FUNDED BY |
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| APPLICANT(S) | Maria Morabito (Boston, Massachusetts); Michael Bianchetta (Roslindale, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Maria Morabito (Boston, Massachusetts); Michael Bianchetta (Roslindale, Massachusetts) |
| ABSTRACT | The instant invention is based, at least in part, on a newly-identified proteasome-independent signaling function of ubiquitinated PSD-95. Mdm2 inhibitors, Mdm4 inhibitors, PSD-95 inhibitors, and/or enantiomers and/or derivatives thereof decrease endocytosis via preventing PSD-95 ubiquitination, and thereby increase AMPAR, NMDAR, D1 dopamine receptor surface expression in response to a given stimulus (e.g., NMDA, Aβ). Accordingly, the invention provides methods for modulating AMPARs, NMDARs, or D1 dopamine receptors in a neuronal cell by contacting the neuronal cell with an Mdm2 and/or Mdm4 inhibitor or PSD-95 inhibitor and/or enantiomers and/or derivatives thereof. Mdm2 and/or Mdm4 inhibitors decrease the enzymatic activity of the respective proteins, and/or interactions with their respective substrates. Mdm2 and Mdm4 inhibitors and/or PSD-95 inhibitors of the invention are contemplated for use in the treatment of neurological disorders, neurodevelopmental disorders, and psychiatric disorders. The invention also provides methods to screen for new Mdm2 and Mdm4 inhibitors and PSD-95 inhibitors and/or enantiomers and/or derivatives thereof. |
| FILED | Monday, November 14, 2011 |
| APPL NO | 13/884705 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/155 (20130101) A61K 31/381 (20130101) A61K 31/435 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/4035 (20130101) A61K 31/4155 (20130101) A61K 31/4164 (20130101) A61K 31/4439 (20130101) A61K 31/4709 (20130101) A61K 31/5513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016421 | Sotomayor et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Eduardo M. Sotomayor (Tampa, Florida); Alejandro V. Villagra (Tampa, Florida) |
| ABSTRACT | Disclosed are methods whereby an effective amount of a HDAC6 inhibitor is used to activate a subjects T-cell response to tumor or tumor vaccine. Methods of using HDAC6 inhibitors to increase a subjects anti-tumor immune response, alone or in conjunction with other tumor treatments, are also disclosed. |
| FILED | Monday, April 06, 2015 |
| APPL NO | 15/120053 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/17 (20130101) A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/416 (20130101) A61K 31/416 (20130101) A61K 31/422 (20130101) A61K 31/422 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/505 (20130101) Original (OR) Class A61K 31/505 (20130101) A61K 39/0011 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) A61K 2039/545 (20130101) A61K 2039/585 (20130101) A61K 2039/5158 (20130101) A61K 2039/55511 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 2501/065 (20130101) C12N 2501/2302 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016432 | Jacobson et al. |
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| APPLICANT(S) | Legacy Emanuel Hospital and Health Center (Portland, Oregon); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Legacy Emanuel Hospital and Health Center (Portland, Oregon); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth Alan Jacobson (Silver Spring, Maryland); Detlev Boison (Portland, Oregon); Kiran Shambhu Toti (Rockville, Maryland) |
| ABSTRACT | Adenosine kinase inhibitors, including pharmaceutical compositions containing the adenosine kinase inhibitors, and their use for preventing epilepsy and its progression in patients. The adenosine kinase inhibitors have the formula: where the moieties J and K, considered in combination, are —CH2—, or K and L, considered in combination, are —CH2—. The R1 moiety can be —NH2, C1-C6 alkyl, C1-C6 alkoxy, or C1-C6 hydroxyalkyl. The R2 and R3 moieties are each independently C1-C6 alkyl. The R4 moiety is hydrogen or C1-C6 alkyl. The R5 and R6 moieties are each independently C6-C12 aryl, C3-C8 cycloalkyl, or C3-C8 heteroaryl, that is optionally further substituted. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 15/607379 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class Heterocyclic Compounds C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016480 | Rudloff et al. |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Riptide Bioscience, Inc. (Vallejo, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia); Riptide Bioscience, Inc. (Vallejo, California) |
| INVENTOR(S) | Udo Rudloff (Bethesda, Maryland); Jesse M. Jaynes (Auburn, Alabama); Henry W. Lopez (Napa, California); George R. Martin (Rockville, Maryland); Clayton Yates (Auburn, Alabama) |
| ABSTRACT | Methods for treating a subject for pancreatic cancer via administration of small anti-inflammatory peptides are disclosed. The peptides may be administered in conjunction with another therapeutic agent, such as a chemotherapeutic agent, or therapeutic regimen. In some cases, the anti-inflammatory peptide that finds use in the subject methods has the amino acid sequence Lys-Phe-Arg-Lys-Ala-Phe-Lys-Arg-Phe-Phe (SEQ ID NO:1) or a multimer, derivative, or variant thereof. |
| FILED | Tuesday, October 13, 2015 |
| APPL NO | 15/518216 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/282 (20130101) A61K 31/337 (20130101) A61K 31/513 (20130101) A61K 31/519 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 38/08 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/48215 (20130101) A61K 47/48284 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016485 | Cox et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bolder Biotechnology, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | Bolder Biotechnology, Inc. (Boulder, Colorado) |
| INVENTOR(S) | George N. Cox (Louisville, Colorado); Christie M. Orschell (Indianapolis, Indiana) |
| ABSTRACT | Methods and compositions for the use of long-acting hematopoietic factor protein analogs for accelerating hematopoietic recovery in subjects who have been or will be exposed to radiation are disclosed. |
| FILED | Thursday, March 17, 2016 |
| APPL NO | 15/073246 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/27 (20130101) A61K 38/193 (20130101) A61K 38/2073 (20130101) Original (OR) Class A61K 47/60 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016486 | Pyun et al. |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Dong-Chul Pyun (Tucson, Arizona); Theodore J. Price (Tucson, Arizona); Gregory D. Dussor (Tucson, Arizona); Dipti Tillu (Tucson, Arizona); Bo Lian (Tucson, Arizona) |
| ABSTRACT | Methods and compositions using a combination of adenosine monophosphate protein kinase (AMPK) activators for treating pain such as post-surgical pain or development of chronic pain. The two or more AMPK activators work synergistically and may be administered in individually sub-efficacious doses. The AMPK activators may have different mechanisms of AMPK activation. The AMPK activators may be administered systemically and/or topically in, for example, as a gel, ointment, cream, lotion, suspension, liquid, or transdermal patch. |
| FILED | Tuesday, December 01, 2015 |
| APPL NO | 14/956042 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/155 (20130101) A61K 31/616 (20130101) A61K 31/4365 (20130101) A61K 31/4375 (20130101) A61K 31/4439 (20130101) A61K 31/7056 (20130101) A61K 38/02 (20130101) A61K 38/185 (20130101) A61K 38/204 (20130101) A61K 38/2264 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016498 | Bertozzi et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carolyn R. Bertozzi (Stanford, California); Mary Sloan Siegrist Palmore (Berkeley, California); John C. Jewett (Berkeley, California); Chelsea G. Gordon (Berkeley, California); Peyton Shieh (La Jolla, California) |
| ABSTRACT | The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704977 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/385 (20130101) Original (OR) Class A61K 47/64 (20170801) A61K 47/646 (20170801) A61K 2039/6068 (20130101) Peptides C07K 9/00 (20130101) C07K 9/001 (20130101) C07K 14/195 (20130101) C07K 14/4725 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016499 | Messersmith et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Kvar C. L. Black (Evanston, Illinois); Ji Yi (Evanston, Illinois); Jose G. Rivera (Waukegan, Illinois) |
| ABSTRACT | The present invention provides nanoparticles including a metallic core having a length along each axis of from 1 to 100 nanometers and a coating disposed on at least part of the surface of the metallic core, wherein the coating comprises polydopamine, along with methods for making and using such nanoparticles. The metallic core may be gold, silver or iron oxide and the polydopamine coating may have other substances bound to it, such as silver, targeting ligands or antibodies, or other therapeutic or imaging contrast agents. The disclosed nanoparticles can be targeted to cells for treating cancer or bacterial infections, and for use in diagnostic imaging. |
| FILED | Wednesday, April 13, 2016 |
| APPL NO | 15/098063 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 9/0092 (20130101) A61K 9/1611 (20130101) A61K 9/1641 (20130101) A61K 9/1676 (20130101) A61K 9/1682 (20130101) A61K 9/5094 (20130101) A61K 31/69 (20130101) A61K 33/00 (20130101) A61K 33/26 (20130101) A61K 33/38 (20130101) A61K 39/40 (20130101) A61K 39/39558 (20130101) A61K 41/0052 (20130101) Original (OR) Class A61K 41/0057 (20130101) A61K 45/06 (20130101) A61K 47/6923 (20170801) A61K 49/1857 (20130101) A61K 49/1875 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) B82Y 40/00 (20130101) Peptides C07K 16/00 (20130101) C07K 16/30 (20130101) C07K 16/2863 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/4795 (20130101) G01N 33/553 (20130101) G01N 33/587 (20130101) G01N 33/54346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016517 | York et al. |
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| FUNDED BY |
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| APPLICANT(S) | Adam W. York (Princeton, New Jersey); Prabhas V. Moghe (Basking Ridge, New Jersey); Kathryn E. Uhrich (Plainfield, New Jersey); Robert Prud'homme (Lawrenceville, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Adam W. York (Princeton, New Jersey); Prabhas V. Moghe (Basking Ridge, New Jersey); Kathryn E. Uhrich (Plainfield, New Jersey); Robert Prud'homme (Lawrenceville, New Jersey) |
| ABSTRACT | The present invention relates to nanoparticle compositions and treatment of cardiovascular disease using nanoparticles to target Class A and B scavenger receptors. This invention further relates to methods of detecting cells that express scavenger receptors, detecting atherosclerotic lesions, and targeting bioactive amphiphilic macromolecules to cells that express scavenger receptors. |
| FILED | Wednesday, August 08, 2012 |
| APPL NO | 14/237974 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/51 (20130101) A61K 9/141 (20130101) A61K 9/513 (20130101) A61K 47/542 (20170801) A61K 47/6425 (20170801) A61K 47/6907 (20170801) A61K 49/0082 (20130101) A61K 49/0093 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 31/16 (20130101) A61L 2300/44 (20130101) A61L 2300/442 (20130101) A61L 2300/624 (20130101) A61L 2400/12 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016524 | Kearney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Cathal J. Kearney (Boston, Massachusetts); Uyanga Tsedev (Cambridge, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Aristidis Veves (Quincy, Massachusetts); Thomas Michael Braschler (Quincy, Massachusetts); Sidi A. Bencherif (Dorchester, Massachusetts) |
| ABSTRACT | The invention provides a solution to the drawbacks associated with conventional alginate dressings. This invention features improved alginate dressings or bandages as well as a fabrication process that results in an alginate sheet that is preloaded with drug, can be stored in a freeze-dried state, and is compliant and ready to use at the time of administration. |
| FILED | Friday, April 11, 2014 |
| APPL NO | 14/783559 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/046 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/28 (20130101) Original (OR) Class A61L 15/28 (20130101) A61L 15/44 (20130101) A61L 15/425 (20130101) A61L 2300/412 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016533 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meng Chen (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meng Chen (Columbia, Missouri) |
| ABSTRACT | Coatings, devices and methods are provided, wherein the contacting surface of a medical device with at least one contacting surface for contacting a bodily fluid or tissue, wherein long-lasting and durable bioactive agents or functional groups are deposited on the contacting surface through a unique two-step plasma coating process with deposition of a thin layer of plasma coating using a silicon-containing monomer in the first step and plasma surface modification using a mixture of nitrogen-containing molecules and oxygen-containing molecules in the second step. The two-step plasma coating process enables the implantable medical device to prevent both restenosis and thrombosis under clinical conditions. The invention also relates to surface treatment of metallic and polymeric biomaterials used for making of medical devices with significantly improved clinical performance and durability. |
| FILED | Monday, March 13, 2017 |
| APPL NO | 15/457575 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/10 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 31/022 (20130101) A61L 33/068 (20130101) A61L 33/0094 (20130101) A61L 2300/42 (20130101) A61L 2300/204 (20130101) A61L 2300/412 (20130101) A61L 2300/416 (20130101) A61L 2400/18 (20130101) A61L 2420/02 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016582 | Hoekman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington Through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | John D. Hoekman (Seattle, Washington); Rodney J. Y. Ho (Mercer Island, Washington) |
| ABSTRACT | The present application discloses devices and methods for delivering a therapeutic compound to the olfactory epithelium of an animal or human. The device having one or more channels for imparting a circumferential and axial velocity to the discharged fluid, and an outlet that discharges an aerosol spray having a circumferential and axial velocity as it enters the nasal cavity of a user. The device is designed to displace the air in the upper nasal cavity in order to specifically deposit a therapeutic agent on the olfactory epithelium while minimizing pressure and discomfort experienced by the user. |
| FILED | Friday, May 30, 2014 |
| APPL NO | 14/292481 |
| ART UNIT | 3778 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/06 (20130101) A61M 15/00 (20130101) A61M 15/08 (20130101) A61M 15/009 (20130101) A61M 31/00 (20130101) Original (OR) Class A61M 2206/14 (20130101) A61M 2206/16 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/10 (20130101) B05B 7/0892 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016590 | Greenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert J Greenberg (Los Angeles, California); Jordan M Neysmith (Mountain View, California); James S Little (Arvada, Colorado); Brian V Mech (Santa Clarita, California); Neil H Talbot (La Cresenta, California) |
| ABSTRACT | The present invention provides a flexible circuit electrode array adapted for neural stimulation, comprising: a polymer base layer; metal traces deposited on the polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on the polymer base layer and the metal traces at least one tack opening. The present invention provides further a method of making a flexible circuit electrode array comprising depositing a polymer base layer; depositing metal on the polymer base layer; patterning the metal to form metal traces; depositing a polymer top layer on the polymer base layer and the metal traces; and preparing at least one tack opening. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 15/475788 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) Original (OR) Class A61N 1/36046 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/036 (20130101) H05K 1/0393 (20130101) H05K 2201/05 (20130101) H05K 2201/053 (20130101) H05K 2201/09063 (20130101) H05K 2201/09409 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016612 | Towe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Bruce Towe (Mesa, Arizona); William Crisp (Paradise Valley, Arizona) |
| ABSTRACT | Methods and devices for stimulating nerves are disclosed. In one embodiment adapted for stimulating excitable tissue, the invention includes drive circuitry, an acoustic transducer and a pair of electrodes. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/376294 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/3787 (20130101) Original (OR) Class A61N 1/36071 (20130101) A61N 1/36125 (20130101) A61N 1/37205 (20130101) A61N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016756 | Lopez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Gabriel P. Lopez (Durham, North Carolina) |
| ABSTRACT | A kit for detection of an analyte of interest in a liquid sample, and methods of using, are provided. The kit may include a pipette and a disposable pipette tip configured to engage the pipette. The pipette tip may define an acoustic channel configured for allowing flow-through of a liquid. The kit may also include a vibratory device in communication with the acoustic channel and configured for imparting a vibratory force thereto. The impartation of the vibratory force may create standing acoustic waves, thereby separating any negative acoustic contrast particles (NACPs) from the remaining contents of the liquid sample. The NACPs may capable of biospecific recognition of the analyte of interest, thereby separating the analytes of interest, which can then be collected or analyzed accordingly. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/466998 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0275 (20130101) Original (OR) Class B01L 2300/0858 (20130101) B01L 2400/0433 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 2001/4094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017441 | Nicewicz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | David A. Nicewicz (Durham, North Carolina); David S. Hamilton (Carrboro, North Carolina) |
| ABSTRACT | A method of making an anti-Markovnikov addition product, comprises reacting an acid with an alkene or alkyne in a dual catalyst reaction system to the exclusion of oxygen to produce said anti-Markovnikov addition product; the dual catalyst reaction system comprising a single electron oxidation catalyst in combination with a hydrogen atom donor catalyst. Dual catalyst composition useful for carrying out such methods are also described. |
| FILED | Friday, May 02, 2014 |
| APPL NO | 14/787179 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0217 (20130101) B01J 31/0239 (20130101) B01J 31/0244 (20130101) B01J 31/1815 (20130101) B01J 31/2295 (20130101) B01J 35/004 (20130101) B01J 2231/324 (20130101) B01J 2531/842 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 37/02 (20130101) Acyclic or Carbocyclic Compounds C07C 41/05 (20130101) Original (OR) Class C07C 67/00 (20130101) Heterocyclic Compounds C07D 207/46 (20130101) C07D 209/26 (20130101) C07D 213/89 (20130101) C07D 291/06 (20130101) C07D 325/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/00 (20130101) C08F 4/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017458 | Booth |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Raymond G. Booth (Boston, Massachusetts) |
| ABSTRACT | The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating 5-HT2C and/or RSK disorders, including diseases and disorders mediated by CPCRs and/or RSKs. |
| FILED | Monday, March 23, 2015 |
| APPL NO | 14/665928 |
| ART UNIT | 1671 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/13 (20130101) Acyclic or Carbocyclic Compounds C07C 211/42 (20130101) Original (OR) Class C07C 217/74 (20130101) C07C 2601/14 (20170501) C07C 2602/10 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017463 | Hedstrom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brandeis University (Waltham, Massachusetts) |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Lizbeth K. Hedstrom (Auburndale, Massachusetts); Marcus J. Long (Lockington, United Kingdom); Ann Parrinello Lawson (Sudbury, Massachusetts) |
| ABSTRACT | Disclosed are small molecule inhibitors of deubiquitinating enzymes (DUBs), and methods of using them. Certain compounds are selective for particular ubiquitin-specific proteases (USPs). |
| FILED | Tuesday, July 21, 2015 |
| APPL NO | 15/327861 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 331/28 (20130101) Original (OR) Class C07C 333/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017475 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | XAVIER UNIVERSITY OF LOUISIANA (New Orleans, Louisiana) |
| ASSIGNEE(S) | XAVIER UNIVERSITY OF LOUSIANA (New Orleans, Louisiana) |
| INVENTOR(S) | Guangdi Wang (New Orleans, Louisiana); Shilong Zheng (New Orleans, Louisiana); Qiu Zhong (New Orleans, Louisiana); Qiang Zhang (Metairie, Louisiana) |
| ABSTRACT | Combretastatins analog compounds and their pharmaceutically acceptable salts are presented, as well as pharmaceutical compositions comprising the combretastatin analog compounds and uses of the combretastatin analog compounds, either alone or in combination with at least one additional therapeutic agent, in the treatment of cancer, and in particular cancer presenting as metastatic tumors. |
| FILED | Thursday, March 26, 2015 |
| APPL NO | 15/129785 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4418 (20130101) A61K 31/4425 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 213/30 (20130101) C07D 213/61 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017478 | Mahajan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Nupam P. Mahajan (Tampa, Florida); Kiran N. Mahajan (Tampa, Florida); Nicholas J. Lawrence (Tampa, Florida); Harshani R. Lawrence (Tampa, Florida) |
| ABSTRACT | Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of Ack1 tyrosine kinase and their use in the treatment of cancer. Methods of screening for new Ack1 tyrosine kinase inhibitors are also disclosed. In specific example, compound having Formula I through IV are disclosed. |
| FILED | Thursday, November 09, 2017 |
| APPL NO | 15/808421 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 53/18 (20130101) Heterocyclic Compounds C07D 239/42 (20130101) C07D 239/48 (20130101) C07D 239/49 (20130101) Original (OR) Class C07D 405/12 (20130101) C07D 405/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017494 | Hoekstra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Viamet Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Mycovia Pharmaceuticals, Inc. (Durham, North Carolina); The United States of America, as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | William J. Hoekstra (Durham, North Carolina); Christopher M. Yates (Raleigh, North Carolina); Mark Behnke (Poolesville, Maryland); Asaf Alimardanov (North Bethesda, Maryland); Scott A. David (Huntsburg, Ohio); Douglas Franklin Fry (Euclid, Ohio) |
| ABSTRACT | The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof. |
| FILED | Thursday, March 19, 2015 |
| APPL NO | 15/126420 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/30 (20130101) C07D 213/38 (20130101) C07D 213/50 (20130101) C07D 213/56 (20130101) C07D 401/06 (20130101) Original (OR) Class C07D 405/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017510 | Bowman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| INVENTOR(S) | Christopher N. Bowman (Boulder, Colorado); Christopher J. Kloxin (Newark, Delaware); Weixian Xi (Boulder, Colorado); Tao Gong (Denver, Colorado); Sankha Pattanayak (Denver, Colorado) |
| ABSTRACT | Click thiol-X monomers and polymers containing such monomers are disclosed. The clickable sequence controllable monomers include an optionally protected thiol moiety; an optionally protected Michael acceptor moiety; a primary functional side chain and one ore more secondary functional side chains. A clickable sequence controllable monomer, can have the structure: wherein independently Y and Z are atoms having a valence electrons of 3 or more; n is a integer from 0-10; m is a integer from 0-10; x is a integer from 0-10; PFS is a functional group SFSi; SFS2; and SFS3 are independently a combination of hydrogen, hydroxyl, aromatic, amine, carboxyl, and carbonyls, optionally substituted to form hydrophilic, hydrophobic, amphiphilic, or charged (positive or negative or both) side chains; T is an optionally protected thiol; and TCA is an optionally protected thiol-click acceptor. Methods of using such polymers are also disclosed. |
| FILED | Friday, February 06, 2015 |
| APPL NO | 15/116978 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/54 (20130101) C07D 473/18 (20130101) C07D 473/34 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1048 (20130101) C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6802 (20130101) C12Q 1/6876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017516 | Alimardanov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services, National Institute of Health (Washington, District of Columbia) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The United States of America, as Represented by the Secretary, Department of Health and Human Services, National Institutes of Health (Washington, District of Columbia) |
| INVENTOR(S) | Asaf Alimardanov (North Bethesda, Maryland); Gregory D. Cuny (Houston, Texas); Gurmit S. Grewal (Lexington, Massachusetts); Arthur Lee (San Jose, California); John C. McKew (Boyds, Maryland); Agustin H. Mohedas (Somerville, Massachusetts); Min Shen (Boyds, Maryland); Xin Xu (Potomac, Maryland); Paul B. Yu (Boston, Massachusetts) |
| ABSTRACT | The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds may also be used to reduce circulating levels of ApoB-100 or LDL and treat or prevent acquired or congenital hypercholesterolemia or hyperlipoproteinemia; diseases, disorders, or syndromes associated with defects in lipid absorption or metabolism; or diseases, disorders, or syndromes caused by hyperlipidemia. |
| FILED | Thursday, May 18, 2017 |
| APPL NO | 15/598540 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017520 | Koehler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Angela N. Koehler (Belmont, Massachusetts); Eric Stefan (Boston, Massachusetts); Francisco Caballero (Brookline, Massachusetts) |
| ABSTRACT | The present disclosure provides compounds of Formula (I-a), Formula (I), and Formula (II). The compounds described herein may be Myc modulators (e.g., Myc inhibitors) and may be useful in treating in a subject in need thereof diseases associated with Myc and proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including a compound described herein. |
| FILED | Thursday, December 10, 2015 |
| APPL NO | 14/965549 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 417/12 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017540 | Henning et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ryan K. Henning (Pasadena, California); Ashwin N. Ram (Pasadena, California); Samir Das (Pasadena, California); Arundhati Nag (Pasadena, California); James R. Heath (South Pasadena, California) |
| ABSTRACT | Cyclic peptides represented by (Formula 1) selectively bind the oncoprotein K-Ras G12D in vitro and in cellulo, where Z1 and Z2 are each L-propargylglycine (Pra), azidoornithine (OrnN3), or L-azidolysine (Az4), and V1-V2-V3-V4-V5 is an amino acid variable region having a sequence selected from the group consisting of SEQ ID NOs: 1-20. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/068528 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) C07K 7/64 (20130101) Original (OR) Class C07K 14/82 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) G01N 2333/82 (20130101) G01N 2333/914 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017542 | Jaynes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| ASSIGNEE(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| INVENTOR(S) | Jesse Jaynes (Auburn, California); L. Edward Clemens (Sacramento, California); Henry W. Lopez (Napa, California); George R. Martin (Rockville, Maryland); Kathryn Woodburn (Saratoga, California) |
| ABSTRACT | Aspects of the present invention relate to peptides having antimicrobial activity. In certain aspects, the invention relates to peptides having potent antimicrobial activity, broad-spectrum antimicrobial activity, and/or the ability to kill otherwise antibiotic-resistant microbes, or microbes protected by biofilms. |
| FILED | Wednesday, March 23, 2016 |
| APPL NO | 15/078794 |
| ART UNIT | 1676 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017543 | Kwong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Huamn Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Peter D. Kwong (Washington, District of Columbia); Barney S. Graham (Rockville, Maryland); Jason S. McLellan (Norwich, Vermont); Jeffrey Boyington (Clarksburg, Maryland); Lei Chen (Rockville, Maryland); Man Chen (Bethesda, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Ivelin Stefanov Georgiev (Gaithersburg, Maryland); Jason Gorman (Washington, District of Columbia); Michael Gordon Joyce (Washington, District of Columbia); Masaru Kanekiyo (Chevy Chase, Maryland); Gilad Ofek (Gaithersburg, Maryland); Marie Pancera (McLean, Virginia); Mallika Sastry (Rockville, Maryland); Cinque Soto (Rockville, Maryland); Sanjay Srivatsan (Lilburn, Georgia); Guillaume Stewart-Jones (Bethesda, Maryland); Yongping Yang (Potomac, Maryland); Baoshan Zhang (Bethesda, Maryland); Tongqing Zhou (Boyds, Maryland) |
| ABSTRACT | Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/776651 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/155 (20130101) A61K 2039/53 (20130101) A61K 2039/543 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) A61K 2039/55505 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/50 (20130101) C07K 2319/70 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10343 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017545 | DeShong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Philip R. DeShong (Silver Spring, Maryland); Lenea Stocker (Silver Spring, Maryland); Daniel C. Stein (Silver Spring, Maryland); Stefanie N. Vogel (Columbia, Maryland); Katharina Richard (Catonsville, Maryland) |
| ABSTRACT | The disclosure relates to compositions, pharmaceutical compositions, vaccines, and methods of making and using the same. The compositions of the disclosure are useful to stimulate an antigen-specific immune response and, in some embodiments, a protective immune response in an animal after challenge to pathogens. The compositions of the disclosure are also useful for treatment and prevention of disease in a subject such as cancer. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/295306 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/095 (20130101) A61K 39/0208 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/22 (20130101) C07K 14/195 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017548 | Malley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Richard Malley (Beverly, Massachusetts); Yingjie Lu (West Roxbury, Massachusetts); Fan Zhang (West Roxbury, Massachusetts) |
| ABSTRACT | The disclosure provides modified biotin-binding proteins which can be expressed in soluble form in high yield in bacteria. Also provided are fusion proteins comprising the modified biotin-binding protein and an antigen. The disclosure further provides non-hemolytic variants of alpha-hemolysin from S. aureus and fusion protein comprising non-hemolytic variant of alpha-hemolysin and a biotin-binding domains. Immunogenic compositions comprising the proteins are also disclosed and use of such immunogenic compositions for inducing an immune response or for vaccinating a subject are also disclosed. |
| FILED | Thursday, November 19, 2015 |
| APPL NO | 14/946372 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/092 (20130101) A61K 39/385 (20130101) A61K 47/61 (20170801) A61K 47/543 (20170801) A61K 47/557 (20170801) A61K 2039/625 (20130101) A61K 2039/627 (20130101) A61K 2039/645 (20130101) A61K 2039/6031 (20130101) A61K 2039/6093 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/31 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017550 | Niederweis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael Niederweis (Homewood, Alabama); Olga Danilchanka (Birmingham, Alabama) |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Michael Niederweis (Homewood, Alabama); Olga Danilchanka (Birmingham, Alabama) |
| ABSTRACT | Provided herein are isolated polypeptides comprising the amino-terminal domain of Mycobacterium tuberculosis porin A (MtpA), wherein the polypeptide is a porin monomer. Also provided are isolated polypeptides comprising the carboxy-terminal domain of Mycobacterium tuberculosis porin A, wherein the polypeptide is a toxin. Also provided are methods of treating or preventing a Mycobacterium tuberculosis (Mtb) infection in a subject with or at risk of developing a Mtb infection. Further provided are chimeric porin polypeptides comprising a first polypeptide comprising an amino-terminal domain of Mycobacterium tuberculosis porin and a second polypeptide comprising an antigen and the use the chimeric porin polypeptides in methods of eliciting an immune response in a subject. |
| FILED | Thursday, August 30, 2012 |
| APPL NO | 14/342057 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/35 (20130101) Original (OR) Class C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/40 (20130101) C07K 2319/42 (20130101) C07K 2319/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 33/5008 (20130101) G01N 33/6872 (20130101) G01N 2333/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017551 | Bielicki et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John K. Bielicki (San Ramon, California); Jan Johansson (San Ramon, California); Waleed Danho (Del Mar, California) |
| ABSTRACT | The present invention provides a family of non-naturally occurring polypeptides having cholesterol efflux activity that parallels that of full-length apolipoproteins (e.g., Apo AI and Apo E), and having high selectivity for ABCA1 that parallels that of full-length apolipoproteins. Further, the peptides of the invention have little or no toxicity when administered at therapeutic and higher doses. The invention also provides compositions comprising such polypeptides, methods of identifying, screening and synthesizing such polypeptides, and methods of treating, preventing or diagnosing diseases and disorders associated with dyslipidemia, hypercholesterolemia, or inflammation; or diseases involving abnormal glucose metabolism, e.g., diabetes, metabolic syndrome; or Alzheimer's Disease or frontotemporal dementia. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/774682 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 45/06 (20130101) A61K 47/48053 (20130101) Peptides C07K 14/435 (20130101) Original (OR) Class C07K 14/775 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017563 | Pier et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gerald B. Pier (Brookline, Massachusetts); Casie Anne Kelly-Quintos (Costa Mesa, California); Lisa Cavacini (Natick, Massachusetts); Marshall R. Posner (Mount Vernon, New York) |
| ABSTRACT | The present invention relates to peptides, particularly human monoclonal antibodies, that bind specifically to poly-N-acetyl glucosamine (PNAG), such as Staphylococcal PNAG, in acetylated, partially acetylated and/or fully deacetylated form. The invention further provides methods for using these peptides in the diagnosis, prophylaxis and therapy of infections by bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Some antibodies of the invention enhance opsonophagocytic killing and in vivo protection against bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Compositions of these peptides, including pharmaceutical compositions, are also provided, as are functionally equivalent variants of such peptides. |
| FILED | Tuesday, September 20, 2016 |
| APPL NO | 15/270461 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1271 (20130101) Original (OR) Class C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017598 | Gao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jinming Gao (Plano, Texas); David Boothman (Dallas, Texas); Kejin Zhou (Dallas, Texas); Xiaonan Huang (Beijing, China PRC); Yiguang Wang (Dallas, Texas) |
| ABSTRACT | Provided herein are block copolymers comprising a hydrophilic polymer segment and a hydrophobic polymer segment, wherein the hydrophilic polymer segment comprises a polymer selected from the group consisting of: poly(ethylene oxide) (PEO), poly(methacrylate phosphatidyl choline) (MPC), and polyvinylpyrrolidone (PVP), wherein the hydrophobic polymer segment comprises wherein R′ is —H or —CH3, wherein R is —NR1R2, wherein R1 and R2 are alkyl groups, wherein R1 and R2 are the same or different, wherein R1 and R2 together have from 5 to 16 carbons, wherein R1 and R2 may optionally join to form a ring, wherein n is 1 to about 10, and wherein x is about 20 to about 200 in total. Also provided are pH-sensitive micelle compositions for therapeutic and diagnostic applications. |
| FILED | Thursday, July 27, 2017 |
| APPL NO | 15/662184 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 9/1273 (20130101) A61K 9/5031 (20130101) A61K 31/337 (20130101) A61K 31/352 (20130101) A61K 31/704 (20130101) A61K 47/58 (20170801) A61K 47/62 (20170801) A61K 47/6811 (20170801) A61K 47/6845 (20170801) A61K 49/005 (20130101) A61K 49/0032 (20130101) A61K 49/0054 (20130101) A61K 49/0056 (20130101) A61K 49/0082 (20130101) Heterocyclic Compounds C07D 311/92 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/34 (20130101) C08F 293/005 (20130101) Original (OR) Class C08F 2438/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017724 | Nikkhah et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mehdi Nikkhah (Scottsdale, Arizona); Roger D. Kamm (Cambridge, Massachusetts); Danh Truong (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mehdi Nikkhah (Scottsdale, Arizona); Roger D. Kamm (Cambridge, Massachusetts); Danh Truong (Tempe, Arizona) |
| ABSTRACT | A microfluidic device for more accurately modeling the in vitro environment in which cancer occurs is disclosed. The device comprises a surface defining one or more microfluidic channels that may further comprise one or more endothelial cells, a first three dimensional scaffold comprising one or more cancer cells that is spatially separated from the one or more microfluidic channels, and a second three dimensional scaffold comprising one or more stromal cells, at least a portion of which is interposed between the one or more microfluidic channels and the first three dimensional scaffold. The second three dimensional scaffold is in fluid communication with both the first three dimensional scaffold and the one or more microfluidic channels. The device can be used to assay anti-cancer agents, or as a system for modeling the growth, behavior, or metastasis and tumor formation of cancer cells. |
| FILED | Thursday, October 01, 2015 |
| APPL NO | 14/872920 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 2300/12 (20130101) B01L 2300/0816 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 25/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017726 | Doyle et al. |
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| FUNDED BY |
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| APPLICANT(S) | Timothy E Doyle (Springville, Utah); Soonjo Kwon (Providence, Utah); Hemangkumar J Patel (Gujarat, India); Jeffrey B. Goodrich (North Logan, Utah) |
| ASSIGNEE(S) | Utah State University (North Logan, Utah) |
| INVENTOR(S) | Timothy E Doyle (Springville, Utah); Soonjo Kwon (Providence, Utah); Hemangkumar J Patel (Gujarat, India); Jeffrey B. Goodrich (North Logan, Utah) |
| ABSTRACT | A method for monitoring a cell culture, where the method includes measuring pulse-echo ultrasonic waveforms from the cell culture, and analyzing the pulse-echo ultrasonic waveforms to monitor the cell culture. |
| FILED | Monday, November 14, 2011 |
| APPL NO | 13/296036 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017728 | Jewett et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Brian Robert Fritz (Chicago, Illinois); Laura Elyse Timmerman (Chicago, Illinois); Yi Liu (Chicago, Illinois) |
| ABSTRACT | A platform for preparing a sequence defined biopolymer in vitro is disclosed. The platform includes a ribosome-depleted cellular extract ribosomal RNAs prepared by in vitro transcription and purified ribosomal proteins depleted of ribosomal RNAs. A method of synthesizing and assembling ribosomes in vitro for use in the platform is provided, as well as a method for preparing a sequence defined biopolymer in vitro using assembling ribosomes and the platform. |
| FILED | Thursday, April 24, 2014 |
| APPL NO | 14/786972 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) C12P 21/00 (20130101) C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017738 | Frank |
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| FUNDED BY |
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| APPLICANT(S) | Markus H. Frank (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Markus H. Frank (Cambridge, Massachusetts) |
| ABSTRACT | The present invention is directed to purified preparations of dermal mesenchymal stem cells that are characterized by the cell surface expression of the ABCB5 P-glycoprotein. The cells may be used for any purpose that mesenchymal stem cells from other course are used. For instance they may be administered to treat an organ transplant recipient to improve allograft survival or as a treatment to patients with autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/832419 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/36 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0625 (20130101) Original (OR) Class C12N 5/0668 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017739 | Tedder et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Thomas F. Tedder (Durham, North Carolina); Ayumi Yoshizaki (Durham, North Carolina); Tomomitsu Miyagaki (Durham, North Carolina); Evgueni Kountikov (Durham, North Carolina); Jonathan C. Poe (Durham, North Carolina) |
| ABSTRACT | Provided herein are methods of expanding B cells, and in particularly B10 cells capable of producing IL-10, ex vivo. The methods include incubation of harvested B cells in the presence of IL-21. Compositions comprising the ex vivo expanded B cells and methods of using the expanded B cell-containing compositions to treat diseases or conditions are also provided. Methods of assessing B10 cell function in a subject are also provided. |
| FILED | Tuesday, March 12, 2013 |
| APPL NO | 13/795889 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0635 (20130101) Original (OR) Class C12N 2501/15 (20130101) C12N 2501/24 (20130101) C12N 2501/52 (20130101) C12N 2501/231 (20130101) C12N 2501/599 (20130101) C12N 2501/2304 (20130101) C12N 2501/2306 (20130101) C12N 2501/2312 (20130101) C12N 2501/2321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017744 | Jaenisch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (Cambridge, Massachusetts) |
| INVENTOR(S) | Rudolf Jaenisch (Brookline, Massachusetts); Konrad Hochedlinger (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state. |
| FILED | Friday, May 05, 2017 |
| APPL NO | 15/588062 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/605 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017761 | Weissman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Sherman M. Weissman (New Haven, Connecticut); Xinghua Pan (Hamden, Connecticut) |
| ABSTRACT | Methods for preparing cDNA libraries from single and low quantities of cells are disclosed. The methods are based on the principles of multi-strand displacement amplification or semi-random primed polymerase chain reaction. The methods typically include a step of reverse transcription and subsequent amplification of cDNA. The methods can be adapted for preparation of cDNA libraries that are representative of mRNA or whole RNA expressed by the cell or cells. The cDNA is suitable for sequencing or microarray analysis. |
| FILED | Monday, December 23, 2013 |
| APPL NO | 14/139612 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) C12N 15/1096 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017762 | Rivera et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Juan Rivera (Mechanicsburg, Pennsylvania); Nicolas Charles (Asnieres sur Seine, France) |
| ABSTRACT | The present disclosure provides methods for inhibiting and/or reducing self-reactive IgE and/or basophils, thereby treating or preventing lupus, lupus nephritis, and lupus-related disorders. |
| FILED | Wednesday, April 26, 2017 |
| APPL NO | 15/498202 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 31/5377 (20130101) A61K 31/5377 (20130101) A61K 31/5383 (20130101) A61K 39/395 (20130101) A61K 39/39533 (20130101) A61K 39/39566 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/4291 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017765 | Gomez et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Christopher M. Gomez (Chicago, Illinois); Xiaofei Du (Chicago, Illinois) |
| ABSTRACT | The disclosure provides methods of treating polyglutamine diseases, e.g., spinocerebellar ataxia Type 6, in a subject, comprising administering to the subject an IRES inhibitor in an amount effective for treating the SCA6 in the subject. Also provided herein are the IRES inhibitors, and pharmaceutical compositions comprising the same. |
| FILED | Wednesday, July 02, 2014 |
| APPL NO | 15/024492 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/70 (20130101) A61K 31/7084 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/141 (20130101) C12N 2310/314 (20130101) C12N 2310/3233 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017782 | Rabinovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Peter M. Rabinovich (Madison, Connecticut); Sherman M. Weissman (New Haven, Connecticut); Erkut Bahceci (Hamden, Connecticut); Marina E. Komarovskaya (Milford, Connecticut) |
| ABSTRACT | RNA prepared by in vitro transcription using a polymerase chain reaction (PCR)-generated template can be introduced into a cell to modulate cell activity. This method is useful in de-differentiating somatic cells to pluripotent, multipotent, or unipotent cells; re-differentiating stem cells into differentiated cells; or reprogramming of somatic cells to modulate cell activities such as metabolism. Cells can also be transfected with inhibitory RNAs, such as small interfering RNA (siRNA) or micro RNA (miRNA), or combinations thereof to induce reprogramming of somatic cells. For example, target cells are isolated from a donor, contacted with one or more RNA's causing the cells to be de-differentiated, re-differentiated, or reprogrammed in vitro, and administered to a patient in need thereof. The resulting cells are useful for treating one or more symptoms of a variety of diseases and disorders, for organ regeneration, and for restoration of the immune system. |
| FILED | Monday, February 01, 2016 |
| APPL NO | 15/012285 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/33 (20130101) A61K 35/36 (20130101) A61K 48/005 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2506/094 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017785 | Kafri |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Tal Kafri (Carrboro, North Carolina) |
| ABSTRACT | An integration-defective retroviral vector transfer cassette lacking a functional polypurine tract (PPT) is provided. Also provided are isolated nucleic acids that include a heterologous nucleotide sequence, one or two retroviral long terminal repeats (LTRs), a packaging signal, a rev responsive element, and a eukaryotic promoter, wherein the nucleic acid lacks a functional PPT; vectors that include the disclosed isolated nucleic acids; recombinant retroviral particles and mRNAs thereof; retroviral vector kits; and methods for producing integration-defective vector particles, achieving gene expression of a nucleotide sequence of interest, and inserting a nucleotide sequence of interest into a host cell genome in a site-specific or non-specific manner. |
| FILED | Monday, October 23, 2017 |
| APPL NO | 15/790530 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2740/15043 (20130101) C12N 2740/16043 (20130101) C12N 2800/24 (20130101) C12N 2800/108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017799 | Smolke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Christina D. Smolke (Menlo Park, California); Catherine Thodey (Mountain View, California); Isis Trenchard (Redwood City, California); Stephanie Galanie (Palo Alto, California) |
| ABSTRACT | Aspects of the invention include host cells that are engineered to produce benzylisoquinoline alkaloids (BIAs). The host cells include heterologous coding sequences for a variety of enzymes involved in synthetic pathways from starting compounds to BIAs of the host cell. Also provided are methods of producing the BIAs of interest by culturing the host cells under culture conditions that promote expression of enzymes encoded by the heterologous coding sequences of the host cells. Aspects of the invention further include compositions, e.g., host cells, starting compounds and kits, etc., that find use in methods of the invention. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360763 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0073 (20130101) C12N 9/1007 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/182 (20130101) Original (OR) Class Enzymes C12Y 121/03003 (20130101) C12Y 201/0114 (20130101) C12Y 201/01116 (20130101) C12Y 201/01128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017803 | Benkovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J Benkovic (State College, Pennsylvania); Frank Salinas (Wheaton, Illinois) |
| ABSTRACT | A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is treated with a high fidelity polymerase to permit the replication and amplification of the target nucleic acid sequence. In preferred embodiments, the polymerase comprises a polymerase holoenzyme. In further preferred embodiments, the recombination factor is bacteriophage T4 UvsX protein or homologs from other species, and the polymerase holoenzyme comprises a polymerase enzyme, a clamp protein and a clamp loader protein, derived from viral, bacteriophage, prokaryotic, archaebacterial, or eukaryotic systems. |
| FILED | Tuesday, March 15, 2016 |
| APPL NO | 15/070529 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1027 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2521/507 (20130101) C12Q 2521/513 (20130101) C12Q 2527/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017808 | Samusik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nikolay Samusik (Mountain View, California); Garry P. Nolan (Redwood City, California); Yury Goltsev (Stanford, California) |
| ABSTRACT | A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the oligonucleotide, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/832595 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6818 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017810 | Iafrate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Anthony John Iafrate (Newton, Massachusetts); Long Phi Le (Boston, Massachusetts); Zongli Zheng (Boston, Massachusetts) |
| ABSTRACT | The technology described herein is directed to methods of determining oligonucleotide sequences, e.g. by enriching target sequences prior to sequencing the sequences. |
| FILED | Monday, September 19, 2016 |
| APPL NO | 15/269448 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6855 (20130101) Original (OR) Class C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017813 | Drndic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Marija Drndic (Philadelphia, Pennsylvania); Kimberly Elizabeth Venta (Philadelphia, Pennsylvania); Gabriel Shemer (Jenkintown, Pennsylvania) |
| ABSTRACT | Provided are solid-state nanopore platforms for fast, electronic, label-free and high-resolution analysis of biomolecules. |
| FILED | Wednesday, March 26, 2014 |
| APPL NO | 14/781453 |
| ART UNIT | 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44743 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017814 | Gundlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Illumina, Inc. (San Diego, California) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Illumina, Inc. (San Diego, California) |
| INVENTOR(S) | Jens H. Gundlach (Seattle, Washington); Andrew Laszlo (Seattle, Washington); Ian Derrington (Seattle, Washington); Jeffrey G. Mandell (La Jolla, California) |
| ABSTRACT | The present disclosure provides method and systems for improving nanopore-based analysis of polymers. The disclosure provides methods for selectively modifying one or more monomeric subunit(s) of a kind a pre-analyte polymer that results polymer analyte with a modified subunit. The polymer analyte produces a detectable signal in a nanopore-based system. The detectable signal, and/or its deviation from a reference signal, indicates the location of the modified subunit in the polymer analyte and, thus, permits the identification of the subunit at that location in the original pre-analyte polymer. |
| FILED | Tuesday, September 02, 2014 |
| APPL NO | 14/915611 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Separation B01D 57/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/101 (20130101) C12Q 2523/303 (20130101) C12Q 2525/107 (20130101) C12Q 2525/113 (20130101) C12Q 2525/119 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017821 | Sharp et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Frank Sharp (Davis, California); Glen C Jickling (Sacramento, California) |
| ABSTRACT | The present invention provides methods and compositions for diagnosing and predicting the occurrence of ischemia. For example, the present invention provides methods and compositions for diagnosing and predicting the risk and cause of transient neurological events (TNE) as ischemic or non-ischemic. |
| FILED | Tuesday, August 02, 2016 |
| APPL NO | 15/226844 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/50 (20130101) G01N 2800/324 (20130101) G01N 2800/2871 (20130101) G01N 2800/7019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017822 | Maris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | John M. Maris (Penn Valley, Pennsylvania); Yael P. Mosse (Penn Valley, Pennsylvania); Erica L. Carpenter (Wyndmoor, Pennsylvania) |
| ABSTRACT | Methods and compositions for identifying, diagnosing, and treating neuroblastoma are disclosed. |
| FILED | Thursday, January 15, 2015 |
| APPL NO | 14/597786 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4545 (20130101) A61K 39/39558 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5748 (20130101) G01N 33/57407 (20130101) G01N 2333/82 (20130101) G01N 2333/912 (20130101) G01N 2500/10 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017825 | Scully et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Ralph Scully (Boston, Massachusetts); Nicholas A. Willis (Boston, Massachusetts) |
| ABSTRACT | As described below, the present invention provides quantitative homologous recombination assays developed to characterize the pathogenicity DNA repair polypeptides (e.g., BRCA1, BRCA2, Rad51) and provide urgently needed functional information on the significance of DNA repair variants of uncertain significance (VUS) alleles. The invention also provides a method of generating site-specific recombination at a genomic locus or site-specific genome editing by inhibiting replication at the genomic locus, e.g., involving contacting the genomic locus with polypeptides that specifically bind target sequences at the genomic locus. |
| FILED | Monday, November 16, 2015 |
| APPL NO | 14/941769 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/907 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017832 | Havranek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (Saint Louis, Missouri) |
| INVENTOR(S) | James J. Havranek (St. Louis, Missouri); Chi Zhang (St. Louis, Missouri); Joseph C. Corbo (St. Louis, Missouri); Connie A. Myers (St. Louis, Missouri); Robi D. Mitra (St. Louis, Missouri); Zongtai Qi (St. Louis, Missouri) |
| ABSTRACT | The present invention relates to enzymes, compositions and methods for catalyzing site specific recombination at asymmetric sites. |
| FILED | Thursday, August 25, 2016 |
| APPL NO | 15/247452 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) C12N 15/85 (20130101) C12N 2800/30 (20130101) Enzymes C12Y 207/07 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018634 | Cohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| INVENTOR(S) | Robert E. Cohen (Fort Collins, Colorado); Yun-Seok Choi (Fort Collins, Colorado) |
| ABSTRACT | The present invention provides compositions comprising chimeric polypeptides that bind to free ubiquitin proteins or free ubiquitin-like proteins with high affinity, as well as chimeric polypeptides that bind to both free and conjugated ubiquitin proteins or free and conjugated ubiquitin-like proteins, and methods of using the chimeric polypeptides to determine the amount of free or total ubiquitin or free or total ubiquitin-like proteins in various types of samples. |
| FILED | Wednesday, April 30, 2014 |
| APPL NO | 14/266502 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/435 (20130101) C07K 2319/00 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Enzymes C12Y 304/19012 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) Original (OR) Class G01N 33/6872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018635 | Regnier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novilytic, LLC (North Webster, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fred Regnier (Carmel, Indiana); JinHee Kim (West Lafayette, Indiana) |
| ABSTRACT | The present invention relates to methods for continuous or near-continuous separation and purification of samples, particularly biological samples, to reduce the number or volume of non-targeted analytes in those samples to enable improved mass spectrometric analysis of analytes of interest, and apparatuses for conducting those methods, utilizing a transport agent with a core domain and a binding domain, the transport agent exceeding 200 kiloDaltons or 10 nm, and the binding domain targeted to the analytes of interest, in conjunction with size-exclusion based chromatography to separate the transport agent-analyte of interest complex from non-targeted analytes that are not bound, or are only non-specifically bound, to the transport agent. |
| FILED | Thursday, July 30, 2015 |
| APPL NO | 14/814081 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class G01N 33/54313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018695 | Deisseroth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Karl Deisseroth (Stanford, California); Jin Hyung Lee (Stanford, California) |
| ABSTRACT | Disclosed herein are systems and methods involving the use of magnetic resonance imaging and optogenetic neural stimulation. Aspects of the disclosure include modifying a target neural cell population in a first region of a brain to express light-responsive molecules. Using a light pulse, the light-responsive molecules in the target neural cell population are stimulated. Multiple regions of the brain are scanned via magnetic resonance imaging. The scans allow for observation of a neural reaction in response to the stimulation in at least one of the multiple regions of the brain. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 15/425925 |
| ART UNIT | 3769 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/4848 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0622 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Original (OR) Class G01R 33/4808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019656 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lehigh University (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | LEHIGH UNIVERSITY (, None) |
| INVENTOR(S) | Xiaolei Huang (Center Valley, Pennsylvania); Sunhua Wan (Bethlehem, Pennsylvania); Chao Zhou (Bethlehem, Pennsylvania) |
| ABSTRACT | A computer diagnostic system and related method are disclosed for automatically classifying tissue types in an original tissue image captured by an imaging device based on texture analysis. In one embodiment, the system receives and divides the tissue image into multiple smaller tissue block images. A combination of local binary pattern (LBP), average LBP (ALBP), and block-based LBP (BLBP) feature extractions are performed on each tissue block. The extractions generate a set of LBP, ALBP, and BLBP features for each block which are used to classify its tissue type. The classification results are visually displayed in a digitally enhanced map of the original tissue image. In one embodiment, a tissue type of interest is displayed in the original tissue image. In another or the same embodiment, the map displays each of the different tissue types present in the original tissue image. |
| FILED | Wednesday, April 13, 2016 |
| APPL NO | 15/097780 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00147 (20130101) G06K 9/628 (20130101) Original (OR) Class G06K 9/629 (20130101) G06K 9/6271 (20130101) G06K 2009/4666 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 7/40 (20130101) G06T 7/41 (20170101) G06T 11/60 (20130101) G06T 2207/10056 (20130101) G06T 2207/10101 (20130101) G06T 2207/20021 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019912 | Eagleman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas); William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas); William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | David M. Eagleman (Houston, Texas); Scott Novich (Dallas, Texas) |
| ABSTRACT | A hearing device may provide hearing-to-touch sensory substitution as a therapeutic approach to deafness. Through use of signal processing on received signals, the hearing device may provide better accuracy with the hearing-to-touch sensory substitution by extending beyond the simple filtering of an incoming audio stream as found in previous tactile hearing aids. The signal processing may include low bitrate audio compression algorithms, such as linear predictive coding, mathematical transforms, such as Fourier transforms, and/or wavelet algorithms. The processed signals may activate tactile interface devices that provide touch sensation to a user. For example, the tactile interface devices may be vibrating devices attached to a vest, which is worn by the user. The vest may also provide other types of information to the user. |
| FILED | Tuesday, March 07, 2017 |
| APPL NO | 15/452207 |
| ART UNIT | 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/045 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 6/00 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 21/003 (20130101) G09B 21/009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10021135 | Michaels et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Spencer Michaels (Miami, Florida); Kemal Akkaya (Miami, Florida); A. Selcuk Uluagac (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Spencer Michaels (Miami, Florida); Kemal Akkaya (Miami, Florida); A. Selcuk Uluagac (Miami, Florida) |
| ABSTRACT | Methods, systems, and devices for instituting a new type of attack on Zigbee networks are provided. Targeting the data-collection aspect of Zigbee's use cases, a denial-of-service attack can be implemented, and can induce loss of the data transmitted from an end device to the coordinator of the network. Such an attack can exploit the fact that the handshake for a newly joining node to the Zigbee coordinator is not encrypted. Methods, systems, and devices to mitigate such an attack are also provided. To mitigate such a type of attack, a low-overhead countermeasure can be implemented, based on a challenge-response. |
| FILED | Thursday, January 04, 2018 |
| APPL NO | 15/862073 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/18 (20130101) H04L 63/1425 (20130101) H04L 63/1483 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/80 (20180201) H04W 12/12 (20130101) H04W 76/10 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10016490 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yunfeng Lu (Culver City, California); Ming Yan (Los Angeles, California); Yang Liu (Los Angeles, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yunfeng Lu (Culver City, California); Ming Yan (Los Angeles, California); Yang Liu (Los Angeles, California) |
| ABSTRACT | Provided are nanocomplexes having at least two different enzymes and a polymeric network anchored to at least one of the enzymes. In some embodiments, the activities of the enzymes catalyze a cascade reaction. |
| FILED | Friday, July 06, 2012 |
| APPL NO | 14/130873 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/44 (20130101) A61K 38/443 (20130101) Original (OR) Class A61K 47/48092 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016819 | McCracken |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | John E. McCracken (Glen Mills, Pennsylvania) |
| ABSTRACT | A body may be provided having first and second ends having threaded outer surfaces. A bore may extend between the first and second ends. A tool may be provided having a first outer mold-line surface, a second opposing surface, and a hole extending between the first and second opposing surfaces. The first end may be threadedly attached and sealed, at the second opposing surface, to an inner surface of the hole. A cap may be threadedly attached and sealed to the second end of the body. A composite may be consolidated against the first outer mold-line surface of the tool. The cap may be unthreadedly removed from the second end. A drill bit may be inserted into the bore, through the tool hole, and against the composite to drill a composite hole. |
| FILED | Thursday, April 24, 2014 |
| APPL NO | 14/260675 |
| ART UNIT | 3722 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Turning; Boring B23B 49/02 (20130101) Original (OR) Class B23B 2215/04 (20130101) B23B 2222/84 (20130101) B23B 2226/27 (20130101) B23B 2260/126 (20130101) B23B 2260/138 (20130101) B23B 2270/34 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/545 (20130101) Technical Subjects Covered by Former US Classification Y10T 408/03 (20150115) Y10T 408/568 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017248 | Samuel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daedalus Flight Systems, LLC (Rockville, Maryland); University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Daedalus Flight Systems, LLC (Rockville, Maryland) |
| INVENTOR(S) | Paul D. Samuel (Rockville, Maryland); Imraan Faruque (Charlottesville, Virginia); James Sean Humbert (San Francisco, California) |
| ABSTRACT | An autonomous flapping wing aerial vehicle can have a vehicle body, a pair of flapping wings, tunable wing hinges, and elastic drive mechanisms. The tunable wing hinges can be coupled to the flapping wings. Each wing hinge can be constructed to deliver a force to a respective one of the flapping wings to alter end points of a stroke thereof. The elastic drive mechanisms can rotate the flapping wings about pivot points to produce the strokes of the flapping wings. The elastic drive mechanism can be driven at or near a resonance thereof. Alterations to the strokes of the flapping wings produced by the combined effect of the tunable wing hinges and the elastic drive mechanisms, operating in parallel, can provide steering control of the aerial vehicle. |
| FILED | Tuesday, April 28, 2015 |
| APPL NO | 14/698375 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 33/02 (20130101) Original (OR) Class B64C 39/024 (20130101) B64C 2201/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017263 | Litwinowicz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Anthony Litwinowicz (Derby, Connecticut); Kwok Cheng (Shelton, Connecticut) |
| ABSTRACT | An impact mitigation system for an aircraft and method of deploying the impact mitigation system is disclosed. A state parameter of the aircraft is obtained. The state parameter is used with an aircraft performance model to determine an acceleration capability of the aircraft. A trajectory of the aircraft is predicted using the state parameter of the aircraft and the acceleration capability of the aircraft. A location of an object with respect to the aircraft is determined and the impact mitigation system is deployed when the predicted trajectory indicates a contact with the object at a predicted contact velocity higher than a threshold velocity at a future time. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 15/422941 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 25/00 (20130101) B64C 27/04 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 25/00 (20130101) Original (OR) Class B64D 45/00 (20130101) B64D 2201/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017429 | Daniels et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho); Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Michael A Daniels (Idaho Falls, Idaho); Ronald J Heaps (Idaho Falls, Idaho); Michelle Pantoya (Lubbock, Texas) |
| ABSTRACT | An energetic material comprising an elemental fuel, an oxidizer or other element, and a carbon nanofiller or carbon fiber rods, where the carbon nanofiller or carbon fiber rods are substantially homogeneously dispersed in the energetic material. Methods of tailoring the electrostatic discharge sensitivity of an energetic material are also disclosed. Energetic materials including the elemental fuel, the oxidizer or other element, and an additive are also disclosed, as are methods of reducing ignition sensitivity of the energetic material including the additive. The additive is combined with the elemental fuel and a metal oxide to form the energetic material. The energetic material is heated at a slow rate to render inert the energetic material to ignition while the energetic material remains ignitable when heated at a fast rate. |
| FILED | Tuesday, July 28, 2015 |
| APPL NO | 14/811703 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0091 (20130101) Original (OR) Class C06B 23/005 (20130101) C06B 23/009 (20130101) C06B 27/00 (20130101) C06B 33/00 (20130101) Detonating or Priming Devices; Fuses; Chemical Lighters; Pyrophoric Compositions C06C 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017542 | Jaynes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| ASSIGNEE(S) | Riptide Bioscience, Inc. (Vallejo, California) |
| INVENTOR(S) | Jesse Jaynes (Auburn, California); L. Edward Clemens (Sacramento, California); Henry W. Lopez (Napa, California); George R. Martin (Rockville, Maryland); Kathryn Woodburn (Saratoga, California) |
| ABSTRACT | Aspects of the present invention relate to peptides having antimicrobial activity. In certain aspects, the invention relates to peptides having potent antimicrobial activity, broad-spectrum antimicrobial activity, and/or the ability to kill otherwise antibiotic-resistant microbes, or microbes protected by biofilms. |
| FILED | Wednesday, March 23, 2016 |
| APPL NO | 15/078794 |
| ART UNIT | 1676 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017547 | Savarino |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Naval Medical Research Center (Silver Spring, Maryland) |
| ASSIGNEE(S) | Naval Medical Research Center (Silver Spring, Maryland) |
| INVENTOR(S) | Stephen J. Savarino (Kensington, Maryland) |
| ABSTRACT | The inventive subject matter relates to the methods for the induction of immunity and prevention of diarrhea resulting from Escherichia coli. The inventive subject matter also relates to the use Escherichia coli adhesins as immunogens and to the construction of conformationally stability and protease resistant Escherichia coli adhesin constructs useful for inducing immunity to Escherichia coli pathogenic bacteria. The methods provide for the induction of B-cell mediated immunity and for the induction of antibody capable of inhibiting the adherence and colonization of Escherichia coli, including enterotoxigenic Escherichia coli, to human cells. |
| FILED | Monday, June 08, 2015 |
| APPL NO | 14/733421 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0258 (20130101) A61K 2039/523 (20130101) A61K 2039/545 (20130101) Peptides C07K 14/245 (20130101) Original (OR) Class C07K 16/1232 (20130101) C07K 2317/55 (20130101) C07K 2319/00 (20130101) C07K 2319/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017650 | Kaiser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AMERICAN STERILIZER COMPANY (Mentor, Ohio) |
| ASSIGNEE(S) | AMERICAN STERILIZER COMPANY (Mentor, Ohio) |
| INVENTOR(S) | Herbert J. Kaiser (Pontoon Beach, Illinois); Miranda C. Shaver (Saint Louis, Missouri); Timothy Lee Giddens (Florissant, Missouri) |
| ABSTRACT | Reactive compositions are provided, having biocidal and chemical decontamination/neutralization properties, comprising a hygroscopic polymer and an active, which are useful in a variety of commercial, healthcare and military applications and a wide variety of contaminants, including without limitation chemical and biological warfare agents. The reactive compositions are renewable or rechargeable after use by exposure to an additional application of the active and do not require removal, disposal or replacement of the originally applied composition. Methods for preparing and applying the reactive compositions are disclosed. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142333 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 25/10 (20130101) A01N 25/34 (20130101) A01N 25/34 (20130101) A01N 59/00 (20130101) A01N 59/00 (20130101) A01N 59/06 (20130101) A01N 59/06 (20130101) Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 5/00 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 1/28 (20130101) B05D 3/007 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) Original (OR) Class C09D 139/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017700 | Yelvington et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
| ASSIGNEE(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
| INVENTOR(S) | Paul E. Yelvington (Rockledge, Florida); Dustin J. Zastrow (Indianlantic, Florida); Nicholas R. Schwartz (Rockledge, Florida) |
| ABSTRACT | An apparatus and method are described for high-yield fast pyrolysis of biomass feedstock to produce a liquid bio-oil product. A bubbling fluidized bed reactor is provided having an integrated, rapid quench apparatus for minimizing secondary cracking reactions that can otherwise lower the yield of bio-oil. A quench stream is provided inside the reactor to minimize the residence time that the product vapors spend at high temperature where cracking can occur. The quench stream is introduced downstream of the fluidized bed but still internal to the reactor. The fluidized bed medium is constrained to the bottom of the reactor and is not cooled by the quench stream. |
| FILED | Wednesday, September 17, 2014 |
| APPL NO | 14/488337 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/24 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017706 | Loebick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Codruta Loebick (North Haven, Connecticut); Jeffrey Weissman (Guilford, Connecticut) |
| ABSTRACT | A stabilized composition comprising a liquid hydrocarbon fuel, such as JP-8, and a fuel additive, wherein the fuel additive comprises a graphitic carbon compound functionalized with a plurality of alkyl groups, wherein at least one alkyl group at each site of alkyl functionalization on the graphitic carbon compound has 8 or more carbon atoms, for example, poly(octadecyl)-graphene oxide. A method of increasing the energy density of a liquid hydrocarbon fuel involving adding to the fuel one or more alkyl-functionalized graphitic carbon compounds. The stabilized composition is useful for enhancing the properties of combustion processes, including energy density, thrust, flame speed, or a combination thereof, without introducing undesirable combustion effects, emissions, or combustion signature. |
| FILED | Monday, March 23, 2015 |
| APPL NO | 14/665395 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/22 (20130101) Original (OR) Class C10L 1/224 (20130101) C10L 2200/0259 (20130101) C10L 2230/22 (20130101) C10L 2270/04 (20130101) Removal or Treatment of Combustion Products or Combustion Residues; Flues F23J 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017728 | Jewett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Brian Robert Fritz (Chicago, Illinois); Laura Elyse Timmerman (Chicago, Illinois); Yi Liu (Chicago, Illinois) |
| ABSTRACT | A platform for preparing a sequence defined biopolymer in vitro is disclosed. The platform includes a ribosome-depleted cellular extract ribosomal RNAs prepared by in vitro transcription and purified ribosomal proteins depleted of ribosomal RNAs. A method of synthesizing and assembling ribosomes in vitro for use in the platform is provided, as well as a method for preparing a sequence defined biopolymer in vitro using assembling ribosomes and the platform. |
| FILED | Thursday, April 24, 2014 |
| APPL NO | 14/786972 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) C12P 21/00 (20130101) C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017808 | Samusik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nikolay Samusik (Mountain View, California); Garry P. Nolan (Redwood City, California); Yury Goltsev (Stanford, California) |
| ABSTRACT | A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the oligonucleotide, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 15/832595 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6818 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017861 | Silvernail et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nathan J. Silvernail (Allison Park, Pennsylvania); Mark W. McMillen (Cabot, Pennsylvania); Shan Cheng (Sewickley, Pennsylvania) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Nathan J. Silvernail (Allison Park, Pennsylvania); Mark W. McMillen (Cabot, Pennsylvania); Shan Cheng (Sewickley, Pennsylvania) |
| ABSTRACT | Disclosed are methods for treating metal substrates that include contacting the substrate with a pretreatment composition comprising a rare earth metal and a zirconyl compound. The present invention also relates to coated substrates produced thereby and further to substrates additionally coated with an electrophoretically applied coating composition. |
| FILED | Wednesday, August 03, 2011 |
| APPL NO | 13/197075 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/50 (20130101) Original (OR) Class C23C 22/53 (20130101) C23C 22/56 (20130101) C23C 22/74 (20130101) C23C 22/83 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/20 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12493 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018054 | Verrilli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (schenectady, New York) |
| INVENTOR(S) | Michael J. Verrilli (Loveland, Ohio); Mark Eugene Noe (West Chester, Ohio); Mark Willard Marusko (Springboro, Ohio); Paul Izon (Morrow, Ohio); Robert Tyler (Harrison, Ohio); Christopher Hasse (Kenwood, Ohio) |
| ABSTRACT | Methods for fabricating a component of a gas turbine engine are provided. In one embodiment, the method includes molding a CMC material to form a first portion of the gas turbine engine component, processing the first portion to form a first assembly, preparing the first assembly and a second portion of the gas turbine engine component for processing, and processing the first assembly and second portion to form a second assembly. In another embodiment, the method includes processing a first plurality of CMC plies to form a first assembly; positioning the first assembly and a second plurality of CMC plies on a tool for processing, the first assembly defining a first plane, the second plurality of plies defining a second plane, wherein the second plane is perpendicular to the first plane; and processing the first assembly and the second plurality of plies to form a second assembly. |
| FILED | Friday, October 23, 2015 |
| APPL NO | 14/921023 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/6269 (20130101) C04B 37/001 (20130101) C04B 2235/602 (20130101) C04B 2235/604 (20130101) C04B 2237/38 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/30 (20130101) F01D 5/147 (20130101) F01D 5/282 (20130101) Original (OR) Class F01D 11/00 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/21 (20130101) F05D 2230/60 (20130101) F05D 2240/30 (20130101) F05D 2300/6033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018062 | Waite et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| INVENTOR(S) | Ryan Alan Waite (Glastonbury, Connecticut); Jeffrey Michael Jacques (East Hartford, Connecticut); Benjamin F. Hagan (Manchester, Connecticut) |
| ABSTRACT | What is described is a transfer tube for use with an airfoil of a gas turbine engine coupled to a platform. The transfer tube includes a main body having a first end defining an inlet configured to receive a flow of fluid and a second end defining an outlet for the flow of fluid, the main body having a curved section. The transfer tube also includes a first mating face coupled to the first end of the main body. The transfer tube also includes a second mating face coupled to the second end of the main body. At least one of the first mating face or the second mating face is configured to be coupled to a platform body of the outer diameter platform. |
| FILED | Thursday, July 02, 2015 |
| APPL NO | 14/790589 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) F01D 9/06 (20130101) F01D 9/065 (20130101) Original (OR) Class F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/12 (20130101) F05D 2260/20 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 9/006 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018064 | Wilber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | John E. Wilber (East Hampton, Connecticut); Craig Hart (Hartford, Connecticut) |
| ABSTRACT | A foil assembly for a gas powered turbine includes a plurality of floating wall sectors arranged circumferentially about an axis defined by a flowpath. Each of the floating wall sectors includes a first flowpath strut component, a second flowpath strut component, a floating wall panel connected to the first flowpath strut component by a first clamp seal at a first axial joint and connected to the second flowpath strut component by a second clamp seal at a second axial joint, and a plurality of leading edge structures fore of the plurality of floating wall sectors. Each of the leading edge structures is configured to define a foil profile in conjunction with a first flowpath strut component of a first floating wall sector and an adjacent flowpath strut component of a second floating wall sector. |
| FILED | Monday, March 02, 2015 |
| APPL NO | 14/635394 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) F01D 5/146 (20130101) F01D 9/041 (20130101) F01D 9/042 (20130101) F01D 11/005 (20130101) Original (OR) Class F01D 25/30 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/642 (20130101) F05D 2240/11 (20130101) F05D 2240/12 (20130101) F05D 2240/55 (20130101) F05D 2240/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018069 | Osborne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Christopher Osborne (Middletown, Connecticut); Adam Nicholas Hart (Middletown, Connecticut) |
| ABSTRACT | The present disclosure includes vane assemblies having a vane lever arm with an inclined profile. The inclined profile may engage with a complementary end of a vane shaft to locate, retain, and prevent rotation of the vane shaft and vane. |
| FILED | Friday, August 28, 2015 |
| APPL NO | 14/838906 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) F01D 17/14 (20130101) Original (OR) Class F01D 17/162 (20130101) F01D 25/28 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/12 (20130101) F05D 2240/35 (20130101) F05D 2260/74 (20130101) F05D 2260/79 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018122 | Hrach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Michael Hrach (West Hartford, Connecticut); Andrew Brehm (West Hartford, Connecticut) |
| ABSTRACT | A filter algorithm for a dual channel electronic engine control system according to one disclosed non-limiting embodiment of the present disclosure includes a division function that divides a measured pressure rate of change of one of a FADEC channel A and FADEC channel B by an average pressure of the FADEC channel A and the FADEC channel B to obtain a resultant value; a first comparator function to bound a proper high resultant value from the division function; a second comparator function to bound a proper low resultant value from the division function; and an OR gate in communication with the first comparator and the second comparator such that if an output from either the first comparator function and the second comparator function is true, that one of the FADEC channel A and the FADEC channel B is filtered out for a time period. |
| FILED | Monday, January 13, 2014 |
| APPL NO | 14/773838 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/00 (20130101) F02C 9/18 (20130101) Original (OR) Class F02C 9/28 (20130101) F02C 9/263 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2200/14 (20130101) F05D 2200/33 (20130101) F05D 2220/32 (20130101) F05D 2240/20 (20130101) F05D 2240/35 (20130101) F05D 2260/84 (20130101) F05D 2260/96 (20130101) F05D 2270/54 (20130101) F05D 2270/70 (20130101) F05D 2270/101 (20130101) F05D 2270/301 (20130101) F05D 2270/309 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 9/03 (20130101) G05B 15/02 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018428 | Altman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David H. Altman (Framingham, Massachusetts); Joseph R. Wasniewski (Watertown, Massachusetts); Anurag Gupta (Canton, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | David H. Altman (Framingham, Massachusetts); Joseph R. Wasniewski (Watertown, Massachusetts); Anurag Gupta (Canton, Massachusetts) |
| ABSTRACT | Methods and apparatus for a heat spreader including a vapor chamber, a fluid in the vapor chamber, a wick disposed in the vapor chamber, the wick comprising a metal wick structure, and a coating on wick comprising carbon nanotubes for promoting incipient boiling of the fluid. |
| FILED | Monday, June 27, 2011 |
| APPL NO | 13/169581 |
| ART UNIT | 3744 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/08 (20130101) F28F 21/084 (20130101) F28F 2255/18 (20130101) F28F 2255/20 (20130101) F28F 2265/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018464 | Boles et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colby D. Boles (Seattle, Washington); Raymond Charles Daley (Richardson, Texas) |
| ASSIGNEE(S) | FlashScan3D, LLC (Richardson, Texas) |
| INVENTOR(S) | Colby D. Boles (Seattle, Washington); Raymond Charles Daley (Richardson, Texas) |
| ABSTRACT | A structured light imaging (SLI) system includes a projection system, image sensor system and processing module. The projection system is operable to project a single SLI pattern into an imaging area. The image sensor system is operable to capture images of a 3D object moving through the imaging area. The image sensor system outputs a subset of camera pixels corresponding to a subwindow of a camera frame to generate subwindow images. The processing module is operable to create a 3D surface map of the 3D object based on the subwindow images. |
| FILED | Wednesday, May 06, 2009 |
| APPL NO | 12/991405 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2513 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/521 (20170101) G06T 2207/10016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018504 | Nazemi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sensors Unlimited, Inc. (Princeton, New Jersey) |
| ASSIGNEE(S) | Sensors Unlimited, Inc. (Princeton, New Jersey) |
| INVENTOR(S) | Jonathan Nazemi (Doylestown, Pennsylvania) |
| ABSTRACT | A method of normalizing FPA system gain for varying temperature includes determining an FPA temperature and calculating an FPA system gain as a function of the FPA temperature, system gain for the FPA at a reference temperature, and empirically derived coefficients. The method also includes applying the FPA system gain at the FPA temperature to condition output of the FPA to produce temperature independent image data. An imaging system includes a focal plane array (FPA). A temperature sensor is operatively connected to measure temperature of the FPA. A module is operatively connected to the FPA and temperature sensor to calculate FPA system gain for the FPA as described above, and to apply the FPA system gain to condition output of the FPA to produce temperature independent image data. There need be no temperature control device, such as a thermoelectric cooling device, connected for temperature control of the FPA. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/939420 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) Original (OR) Class G01J 1/4228 (20130101) G01J 5/16 (20130101) G01J 5/20 (20130101) G01J 2001/444 (20130101) G01J 2005/0048 (20130101) G01J 2005/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018646 | Cranch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Geoffrey A. Cranch (Fairfax Station, Virginia); Jacob Grun (Silver Spring, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Geoffrey A. Cranch (Fairfax Station, Virginia); Jacob Grun (Silver Spring, Maryland) |
| ABSTRACT | A fiber optic pressure and mass velocity sensor for measuring a shock wave pressure in a solid media includes an optical fiber having a means for measuring a change in an optical path length (OPL) of the fiber when positioned in the solid media caused by the shock wave altering the physical length of the fiber and the refractive index of the fiber. The means for measuring the change in the OPL is coupled at one end to a laser and at its second end to a means for detecting the change in OPL. The sensor has a high operating bandwidth (>>10 MHz), is sufficiently rigid to withstand the force of the shock wave, has a sensitivity that can also be tailored for the application, and is immune to electromagnetic interference. Measurement can be made on materials under extreme strain conditions, and the sensor can also provide characterization of protective materials such as bullet/blast proof materials. |
| FILED | Wednesday, September 10, 2014 |
| APPL NO | 14/482580 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/266 (20130101) G01D 5/268 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018686 | Bickford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | James Alan Bickford (Winchester, Massachusetts); Jonathan Jay Bernstein (Medfield, Massachusetts); Marc Steven Weinberg (Needham, Massachusetts); Amy Elizabeth Duwel (Cambridge, Massachusetts); Richard David Elliott, III (North Reading, Massachusetts); Ronald Edmund Gagnon, Jr. (North Grafton, Massachusetts); Joseph Michael Kinast (Cambridge, Massachusetts); John Joseph LeBlanc (North Andover, Massachusetts); Thomas Francis Marinis, Jr. (Haverhill, Massachusetts); Michael Joseph Tomaino-Iannucci (Somerville, Massachusetts); William Joseph Trinkle, Jr. (Arlington, Massachusetts) |
| ABSTRACT | An ultra-low noise sensor for magnetic fields comprises a mechanically resonant structure having a magnetized proof mass. The displacement of the proof mass due to a magnetic field provides a high resolution and highly amplified measurement of magnetic field fluctuations near the resonance frequency. A flux modulator may be used with the resonant structure to amplify magnetic fluctuations in a non-resonant frequency band. The resonant structure, combined with a high resolution readout device and a frequency-compensating numerical processor, can amplify magnetic fluctuations in a broad range of frequencies. A solenoid coil surrounding the resonant structure may be used to null the quasi-static earth's magnetic field and thereby increase the dynamic range of the sensor. Cryogenically cooling the resonant structure can improve the resolution of the sensor. A magnetometer that embodies features of the present invention is miniaturized and has improved amplification and resolution at room temperature. |
| FILED | Wednesday, October 21, 2015 |
| APPL NO | 14/919527 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/035 (20130101) G01R 33/038 (20130101) G01R 33/0047 (20130101) G01R 33/0286 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018707 | Mazzaro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America Army Research Laboratory ATTN: RDRL-LOC-I (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gregory J. Mazzaro (Charleston, South Carolina); Kyle A. Gallagher (Derwood, Maryland) |
| ABSTRACT | A novel methodology for automatically linearizing a harmonic radar transmitter—termed Feed-Forward Filter Reflection (FFFR)—is disclosed. The method combines the reflected second harmonic from a filter with the signal passing directly through the filter. The second harmonic from these two paths are combined with equal and opposite amplitudes to reduce the second harmonic beyond filtering alone. This methodology has been experimentally verified at transmit frequencies between 800 and 1000 MHz. Implemented properly, the technique provides greater than 100 dB rejection between 1.6 and 2.0 GHz. Although the tuning has been automated, further optimization is possible. Automated tuning is demonstrated over 400 MHz of bandwidth with a minimum cancellation of 110 dB. One application for the harmonic cancellation is to create a linear radar transmitter for the remote detection of non-linear targets. |
| FILED | Monday, May 04, 2015 |
| APPL NO | 14/703038 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/032 (20130101) Original (OR) Class G01S 7/35 (20130101) G01S 7/038 (20130101) G01S 7/282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018714 | Liao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | DaHan Liao (Laurel, Maryland) |
| ABSTRACT | A radar system for detecting a target containing electronic components. The radar system includes a radiofrequency transmitter which generates a radar signal at a fundamental frequency. A modulator modulates the radar signal at a modulation frequency and the modulated radar signal is coupled to a transmission antenna. A receiver receives an echo from the radar signal. A filter isolates the harmonics of the fundamental frequency from the echo and a demodulator then compares the phase of the harmonics of the echo with the phase of the harmonics of the radar signal and generates an output signal representative thereof. An imaging algorithm receives the output signal and creates a two-dimensional image of the received echo and then displays that image on a display. |
| FILED | Wednesday, June 24, 2015 |
| APPL NO | 14/748272 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/282 (20130101) G01S 7/285 (20130101) G01S 13/06 (20130101) Original (OR) Class G01S 13/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018857 | Hoffman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert C Hoffman (Woodstock, Virginia); Shizhuo Yin (State College, Pennsylvania) |
| ABSTRACT | An electro-optic modulator comprising at least one nanodisordered potassium tantalate niobate crystal; first and second conductors operatively connected to the nanodisordered potassium tantalate niobate crystal adapted to be connected to a voltage source to modulate light passing there through; whereby light is modulated by passing through the nanodisordered potassium tantalate niobate crystal. A method for modulating light comprising providing at least one at least one nanodisordered potassium tantalate niobate crystal; providing first and second conductors operatively connected to the nanodisordered potassium tantalate niobate crystal adapted to be connected to a voltage source to modulate light passing there through; providing an interrogating light beam striking at least one nanodisordered potassium tantalate niobate crystal; modulating light passing through the nanodisordered potassium tantalate niobate crystal; and receiving a modulated light beam. |
| FILED | Tuesday, September 12, 2017 |
| APPL NO | 15/701892 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/122 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0018 (20130101) G02F 1/0311 (20130101) G02F 1/0316 (20130101) G02F 1/0327 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018916 | Policastro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven A. Policastro (Waldorf, Maryland); Raymond C Y Auyeung (Alexandria, Virginia); Alberto Piqué (Crofton, Maryland); Farrell Martin (Waldorf, Maryland) |
| ABSTRACT | An apparatus for electrochemical experimentation with an isolated microstructural region on a surface comprising a metal sample coated with a photoresist, a region of interest, an exposed region of photoresist and unexposed region of photoresist wherein the exposed region is created by light and creating a developed region of unexposed photoresist, and an adhesive strip with a first perforated window over the region of interest and a sealed waterproof container with a second larger perforated window over the first perforated window. A method for isolating microstructural regions for electrochemical experimentation comprising providing a metal sample, identifying regions of interest, coating the metal sample, selecting regions of interest, exposing with light and creating exposed photoresist and unexposed photoresist by laser lithography without a mask, and immersing the metal sample in a developer solution and creating developed regions of unexposed photoresist. |
| FILED | Tuesday, January 05, 2016 |
| APPL NO | 14/988575 |
| ART UNIT | 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/16 (20130101) G03F 7/26 (20130101) G03F 7/2002 (20130101) Original (OR) Class G03F 7/2053 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/13 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019005 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Walter Wang (Hacienda Heights, California); Jerome H. Wei (La Habra, California); Bradley Feest (Los Alamitos, California); Benjamin Najar-Robles (Arcadia, California); Michael Z. Lim (Playa Del Rey, California) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Walter Wang (Hacienda Heights, California); Jerome H. Wei (La Habra, California); Bradley Feest (Los Alamitos, California); Benjamin Najar-Robles (Arcadia, California); Michael Z. Lim (Playa Del Rey, California) |
| ABSTRACT | One example includes an autonomous vehicle control system. The system includes an operational plan controller to maintain operational plans that each correspond to a predetermined set of behavioral characteristics of an associated autonomous vehicle based on situational awareness data provided from on-board sensors of the autonomous vehicle and mission control data provided from a user interface. The system also includes a decision-making algorithm to select one of the operational plans for operational behavior of the autonomous vehicle based on the situational awareness data and the mission control data at a given time and to provide an intent decision based on the situational awareness data and the selected one of the operational plans. The system further includes an execution engine to provide control outputs to operational components of the autonomous vehicle for navigation and control based on the selected one of the operational plans and in response to the intent decision. |
| FILED | Thursday, September 15, 2016 |
| APPL NO | 15/266708 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019006 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Brual C. Shah (College Park, Maryland); Petr Svec (Burlington, Massachusetts); Satyandra K. Gupta (Clarksville, Maryland) |
| ABSTRACT | A planning module for a water surface vehicle can determine a vehicle trajectory that avoids one or more moving obstacles, such as civilian marine vessels, by performing a lattice-based heuristic search of a state space for the surface vehicle and selecting control action primitives from a predetermined set of control action primitives based on the search. The planning module can separate a travel space into a plurality of regions and can independently scale the control action primitives in each region based on the moving obstacles therein. The heuristic search includes evaluating a cost function at each state of the state space. The cost function can be based on at least predicted movement of the obstacles responsive to respective maneuvers performed by the surface vehicle at each node of the search. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/094295 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 2035/007 (20130101) Marine Propulsion or Steering B63H 25/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/203 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0206 (20130101) Original (OR) Class Traffic Control Systems G08G 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019576 | Jin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Automation, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | Intelligent Automation, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Guang Jin (Germantown, Maryland); Hongmei Deng (Potomac, Maryland); Brandon James Knapp (Rockville, Maryland); Andrew William Henderson (Camillus, New York); Joshua Brandon Tuttle (Silver Spring, Maryland); Renato Levy (N. Potomac, Maryland) |
| ABSTRACT | A security control system is provided that works as an extra layer of defense as a way to prevent an “attack” that is initiated by modifying either the “jump” or the “return” addresses or both. The principal behind the security control system is to “monitor” the addresses to which the processors would jump, interrupt or return, and identify when these addresses are modified in a manner that does not comply with the normal execution of the processor. In order to do that the security control system uses existing structures in multi-core processors and even anticipates the creation of additional structures to expedite and improve such control. |
| FILED | Friday, April 01, 2016 |
| APPL NO | 15/088665 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/566 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019667 | Appuswamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Rathinakumar Appuswamy (San Jose, California); Myron D. Flickner (San Jose, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the present invention provide a method for feature extraction comprising generating synaptic connectivity information for a neurosynaptic core circuit. The core circuit comprises one or more electronic neurons, one or more electronic axons, and an interconnect fabric including a plurality of synapse devices for interconnecting the neurons with the axons. The method further comprises initializing the interconnect fabric based on the synaptic connectivity information generated, and extracting a set of features from input received via the electronic axons. The set of features extracted comprises a set of features with reduced correlation. |
| FILED | Thursday, June 16, 2016 |
| APPL NO | 15/184892 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019669 | Modha |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | The present invention relates to unsupervised, supervised and reinforced learning via spiking computation. The neural network comprises a plurality of neural modules. Each neural module comprises multiple digital neurons such that each neuron in a neural module has a corresponding neuron in another neural module. An interconnection network comprising a plurality of edges interconnects the plurality of neural modules. Each edge interconnects a first neural module to a second neural module, and each edge comprises a weighted synaptic connection between every neuron in the first neural module and a corresponding neuron in the second neural module. |
| FILED | Wednesday, November 18, 2015 |
| APPL NO | 14/945316 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class G06N 3/049 (20130101) G06N 3/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020115 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Qing Wang (Collegeville, Pennsylvania); Qi Li (State College, Pennsylvania) |
| ABSTRACT | Disclosed herein is a dielectric composite comprising an organic polymer that has a glass transition temperature greater than or equal to about 250° C.; and a dielectric filler present in an amount effective to impart to the dielectric composite a dielectric constant that varies by less than 5% over a temperature range of 25° C. to 300° C., with an applied alternating electric field having a frequency of 104 Hz and a maximum operating electric field strength of at least 250 megavolt per meter. Disclosed herein too is a method of manufacturing the dielectric composite and articles that contain the dielectric composite. |
| FILED | Thursday, May 26, 2016 |
| APPL NO | 15/165087 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/12 (20130101) C08G 77/48 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/20 (20130101) C08K 3/28 (20130101) C08K 3/28 (20130101) C08K 3/38 (20130101) C08K 2003/385 (20130101) Compositions of Macromolecular Compounds C08L 65/00 (20130101) C08L 65/00 (20130101) C08L 83/14 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/005 (20130101) H01G 4/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020125 | Phillips et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan Phillips (Pacific Grove, California); Samuel Salvadore Fromille, IV (Kapolei, Hawaii) |
| ABSTRACT | A class of materials is provided that has dielectric constants greater than 105. The super dielectric materials (SDM) can be generated readily from common, inexpensive materials. Various embodiments include a porous, electrically insulating material, such as high surface area powders of silica or titania, mixed with a liquid containing a high concentration of ionic species. In some embodiments, high surface area alumina powders, loaded to the incipient wetness point with a solution of boric acid dissolved in water, have dielectric constants greater than 4×108. |
| FILED | Wednesday, August 17, 2016 |
| APPL NO | 15/239039 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/22 (20130101) H01G 11/56 (20130101) Original (OR) Class H01G 11/62 (20130101) H01G 11/86 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0063 (20130101) H02J 7/345 (20130101) H02J 2007/0067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020343 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FLIR Systems, Inc. (Wilsonville, Oregon) |
| ASSIGNEE(S) | FLIR Systems, Inc. (Wilsonville, Oregon) |
| INVENTOR(S) | Edward K. Huang (Thousand Oaks, California); Andrew D. Hood (Ventura, California); Bryan Gall (Ventura, California); Paula Heu (Santa Barbara, California); Richard E. Bornfreund (Santa Barbara, California) |
| ABSTRACT | Systems and methods may be provided for fabricating infrared focal plane arrays. The methods include providing a device wafer, applying a coating to the device wafer, mounting the device wafer to a first carrier wafer, thinning the device wafer while the device wafer is mounted to the first carrier wafer, releasing the device wafer from the first carrier wafer, singulating the device wafer into individual dies, each die having an infrared focal plane array, and hybridizing the individual dies to a read out integrated circuit. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/275134 |
| ART UNIT | 2896 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1462 (20130101) H01L 27/1465 (20130101) H01L 27/1469 (20130101) H01L 27/14634 (20130101) H01L 27/14685 (20130101) H01L 27/14687 (20130101) Original (OR) Class H01L 27/14694 (20130101) H01L 27/14696 (20130101) H01L 27/14698 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020366 | Mahadik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nadeemullah A. Mahadik (Springfield, Virginia); Robert E. Stahlbush (Silver Spring, Maryland); Eugene A. Imhoff (Washington, District of Columbia); Marko J. Tadjer (Springfield, Virginia) |
| ABSTRACT | A method and device including adding a protective layer on the surface of a substrate, annealing the substrate at a temperature approximately greater or equal to 1850° C., removing the protective layer from the surface of the substrate after the annealing, and growing a first epilayer on the substrate after the removing of the protective layer, wherein the first epilayer is grown without attempting to prevent the basal plane dislocations to propagate in the first epilayer when growing the first epilayer, and wherein the first epilayer is free of the basal plane dislocations. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/272736 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/324 (20130101) H01L 21/02378 (20130101) H01L 21/02433 (20130101) H01L 21/02529 (20130101) H01L 21/02658 (20130101) H01L 29/1608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020438 | Yazdani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Ali Yazdani (Princeton, New Jersey); Andrei Bernevig (Lawrenceville, New Jersey) |
| ABSTRACT | A magnetic topological nanowire structure comprises a superconductor and a quasi-1D magnetic nanowire. The quasi-1D magnetic nanowire is coupled to or embedded in the superconductor to produce a self-contained interaction resulting in a spatially separated pair of Majorana fermions. The pair of Majorana fermions corresponds to the topological superconductor and each of the pair of the Majorana fermions are localized near a respective endpoint of the nanowire. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 14/818002 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0072 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/12 (20130101) H01L 39/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020476 | Fan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | American Lithium Energy Corporation (Vista, California) |
| ASSIGNEE(S) | American Lithium Energy Corporation (Carlsbad, California) |
| INVENTOR(S) | Jiang Fan (San Diego, California) |
| ABSTRACT | An articulate battery case encases a battery ensemble having multiple non-contiguous battery segments flexibly interconnected to one another by conductive leads. The articulate battery case employs a plurality of rigid compartments for encasing the battery ensemble. Each compartment is configured for encasing one non-contiguous battery segment. Each compartment is flexibly connected by one or more flexible hinge to at least one adjoining compartment and is articulate therewith. Each compartment defines one or more ports for interconnecting conductive leads between battery segments encased in adjoining compartments. Each compartment is interconnected to every other compartment, with or without one or more intervening compartment. When a battery ensemble is encased within the articulate battery case, it is rendered articulate, i.e., it acquires the articulation characteristics of the case within which it is contained. |
| FILED | Monday, March 30, 2015 |
| APPL NO | 14/673608 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/206 (20130101) H01M 2/1005 (20130101) H01M 2/1077 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/4911 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020517 | Taylor |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PITTSBURGH ELECTRIC ENGINE, INC. (Mount Pleasant, Pennsylvania) |
| ASSIGNEE(S) | Pittsburgh Electric Engines, Inc. (Mount Pleasant, Pennsylvania) |
| INVENTOR(S) | Owen S. Taylor (Mount Pleasant, Pennsylvania) |
| ABSTRACT | A fuel cell assembly comprising: a plurality of fuel cell bundles, each fuel cell bundle comprising: an array of elongated tubular fuel cells comprising a plurality of rows of spaced apart, elongated tubular fuel cells; a plurality of elongated electrical connectors each having a first contact for coupling with a first fuel cell and a second contact for coupling with a second fuel cell and wherein each of said electrical connectors is disposed between at least two of said elongated tubular fuel cells; an oxidant supply system; a fuel supply system; and a support structure for integrating as a bundle said fuel cells, said oxidant supply system and said fuel supply system, wherein said support structure comprises an elongated tubular fuel cell support/spacer plate and an oxidant feed tube support/spacer plate; wherein the elongated tubular fuel cell support/spacer plate is spaced from and connected to the oxidant feed tube support/spacer plate by one or more first pin-in-sleeve combinations each of which is connected to a first side of the elongated tubular fuel cell support/spacer plate and to a first side of the oxidant feed tube support/spacer plate. The fuel cell assembly may also comprise flexible members defining open slots on electrical connectors. Flexible power leads with cross-over plates and tabs may also be comprised in the fuel cell assembly. |
| FILED | Monday, March 17, 2014 |
| APPL NO | 14/776218 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/004 (20130101) Original (OR) Class H01M 8/12 (20130101) H01M 8/0232 (20130101) H01M 8/243 (20130101) H01M 8/0247 (20130101) H01M 8/248 (20130101) H01M 8/0271 (20130101) H01M 8/2475 (20130101) H01M 8/04022 (20130101) H01M 8/04097 (20130101) H01M 2008/1293 (20130101) H01M 2250/20 (20130101) H01M 2300/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020581 | Diaz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rodolfo Diaz (Phoenix, Arizona); Tara Yousefi (Tempe, Arizona); Tom Sebastian (Tempe, Arizona); Sergio Clavijo (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Rodolfo Diaz (Phoenix, Arizona); Tara Yousefi (Tempe, Arizona); Tom Sebastian (Tempe, Arizona); Sergio Clavijo (Phoenix, Arizona) |
| ABSTRACT | The present disclosure provides systems and methods for enhancing the performance of permeable antennas. Further, the parallel solenoid feed system disclosed herein may be used to reduce or eliminate significant phase delays in antennas, which may lead to destructive interference. Moreover, use of the parallel solenoid feed in an antenna eliminates the need for multiple feeds, complicated feed networks, and elaborate matching circuits. Using the parallel solenoid feed in circular magnetic antennas may enhance the performance of the antenna through maintaining the flux. Finally, many adjustable parameters for further tuning and/or optimizing the performance of particular antenna design have been identified herein, which may allow those skilled in the art to utilize known systems, such as full wave simulation software, to determine the desired final design for an antenna utilizing a parallel solenoid feed. |
| FILED | Monday, June 13, 2016 |
| APPL NO | 15/180822 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10021426 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of The University of Alabama (Tuscaloosa, Alabama); San Diego State University (SDSU) Foundation (San Diego, California) |
| ASSIGNEE(S) | Board of Trustees of The University of Alabama (Tuscaloosa, Alabama); San Diego State University (SDSU) Foundation (San Diego, California) |
| INVENTOR(S) | Fei Hu (Tuscaloosa, Alabama); Yeqing Wu (Tuscaloosa, Alabama); Sunil Kumar (San Diego, California) |
| ABSTRACT | A cross-layer encoder for providing UEP encoding of video data configured to provide UEP encoding of video data at an application layer of a transmission channel by receiving video packets having first and second priority levels, applying first and second coding schemes to video packets having first and second priority levels, respectively, and transmitting video frames having first and second priority levels. The cross-layer encoder can be configured to provide UEP encoding of video data at a physical layer of the transmission channel by receiving encoded video frames having first and second priority levels, applying third and fourth coding schemes to video frames having first and second priority levels, respectively, and transmitting cross-layer encoded video frames having first and second priority levels. The first through fourth coding schemes can generate different percentages of the total coding overhead based on first and second priority levels, respectively. |
| FILED | Friday, September 19, 2014 |
| APPL NO | 14/491092 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 19/67 (20141101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
10021534 — Method for increasing multicast throughput in a single-hop multi-channel wireless network
| US 10021534 | Wasserman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David Robert Wasserman (San Diego, California); Douglas S. Hulbert (San Diego, California) |
| ABSTRACT | A communications method comprising the following steps: establishing a single-hop, multi-channel wireless network comprising a plurality of half-duplex nodes that can simultaneously receive on multiple channels but that cannot simultaneously transmit on the multiple channels; using linear programming to establish a rapid-throughput transmission schedule for data transmissions between the half-duplex nodes; multicasting all the data transmissions in the network in multicast sessions according to the transmission schedule; using erasure coding to reconstruct data transmitted in a particular multicast session in instances where the entirety of the particular multicast session is not received at a given node because the given node was transmitting during part of the particular multicast session. |
| FILED | Tuesday, October 06, 2015 |
| APPL NO | 14/876469 |
| ART UNIT | 2415 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/14 (20130101) H04L 12/189 (20130101) H04L 12/1886 (20130101) Wireless Communication Networks H04W 4/06 (20130101) Original (OR) Class H04W 72/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10016745 | Hunyadi Murph et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Simona E. Hunyadi Murph (Augusta, South Carolina); George K. Larsen (Aiken, South Carolina) |
| ABSTRACT | The present invention is directed to multifunctional nanomaterials for photothermal heating and catalytic applications. The present invention discloses a method of photothermally heating a solution. The present method also discloses a method of catalyzing a reaction. Both methods require a step of exposing a solution to at least one wavelength of the electromagnetic spectrum. A gold-iron oxide nanomaterial comprising an iron oxide substrate and discrete gold particles deposited on the substrate is also disclosed. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/183222 |
| ART UNIT | 1671 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/8906 (20130101) Original (OR) Class B01J 35/023 (20130101) Acyclic or Carbocyclic Compounds C07C 213/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016844 | Farmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Joseph C. Farmer (Tracy, California); Alexander M. Rubenchik (Livermore, California) |
| ABSTRACT | A laser is used to clean surfaces contaminated with chemical, biological, or radioactive substances. The laser directs a laser beam onto the surfaces and the ejecta is collected by a getter which can be a version of vacuum cleaner. A mobile system includes a laser transporting arm and collection system used in cleanup of metal and concrete surfaces contaminated with chemical, biological, or radioactive substances. |
| FILED | Friday, January 16, 2015 |
| APPL NO | 14/599051 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 7/0042 (20130101) B08B 15/02 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/36 (20130101) B23K 26/0884 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/04 (20130101) G01N 2001/021 (20130101) G01N 2001/028 (20130101) Measurement of Nuclear or X-radiation G01T 7/00 (20130101) G01T 7/02 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/02 (20130101) G01V 5/0091 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016914 | Gordon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | N. Ross Gordon (Kennewick, Washington); Scott J. Dilly (Oregon City, Oregon); Kevin L. Simmons (Kennewick, Washington); Leslie J. Woodcock (Benton City, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | N. Ross Gordon (Kennewick, Washington); Scott J. Dilly (Oregon City, Oregon); Kevin L. Simmons (Kennewick, Washington); Leslie J. Woodcock (Benton City, Washington) |
| ABSTRACT | The present invention is a method and apparatus for molding plastic parts and placing and orienting reinforcing fibers within structurally thin sections. More specifically, the method of the present invention is a molding technique wherein positive displacement is applied to incremental sections of a charge (plastic mixed with reinforcing fibers), thereby sequentially forming the desired part and placing reinforcing fibers within structurally thin sections. The apparatus of the invention is a moveable ram that may be tapered and that is in contact with the charge during forming. |
| FILED | Friday, July 31, 1992 |
| APPL NO | 07/923416 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/22 (20130101) B29C 33/40 (20130101) Original (OR) Class B29C 2033/422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017391 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Sheng Dai (Knoxville, Tennessee); Kimberly M. Nelson (Knoxville, Tennessee) |
| ABSTRACT | The invention is directed to a method for fabricating a mesoporous carbon composite material. The method comprises providing a precursor composition and subjecting the precursor material to a curing step followed by carbonization step. The precursor composition comprises (i) a templating component comprised of a linear homopolymer material, (ii) a phenolic compound or material, (iii) a crosslinkable aldehyde component, and (iv) an acid catalyst. |
| FILED | Tuesday, April 19, 2016 |
| APPL NO | 15/132347 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/12 (20130101) Original (OR) Class C01B 32/00 (20170801) C01B 32/30 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017429 | Daniels et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho); Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Michael A Daniels (Idaho Falls, Idaho); Ronald J Heaps (Idaho Falls, Idaho); Michelle Pantoya (Lubbock, Texas) |
| ABSTRACT | An energetic material comprising an elemental fuel, an oxidizer or other element, and a carbon nanofiller or carbon fiber rods, where the carbon nanofiller or carbon fiber rods are substantially homogeneously dispersed in the energetic material. Methods of tailoring the electrostatic discharge sensitivity of an energetic material are also disclosed. Energetic materials including the elemental fuel, the oxidizer or other element, and an additive are also disclosed, as are methods of reducing ignition sensitivity of the energetic material including the additive. The additive is combined with the elemental fuel and a metal oxide to form the energetic material. The energetic material is heated at a slow rate to render inert the energetic material to ignition while the energetic material remains ignitable when heated at a fast rate. |
| FILED | Tuesday, July 28, 2015 |
| APPL NO | 14/811703 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0091 (20130101) Original (OR) Class C06B 23/005 (20130101) C06B 23/009 (20130101) C06B 27/00 (20130101) C06B 33/00 (20130101) Detonating or Priming Devices; Fuses; Chemical Lighters; Pyrophoric Compositions C06C 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017551 | Bielicki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John K. Bielicki (San Ramon, California); Jan Johansson (San Ramon, California); Waleed Danho (Del Mar, California) |
| ABSTRACT | The present invention provides a family of non-naturally occurring polypeptides having cholesterol efflux activity that parallels that of full-length apolipoproteins (e.g., Apo AI and Apo E), and having high selectivity for ABCA1 that parallels that of full-length apolipoproteins. Further, the peptides of the invention have little or no toxicity when administered at therapeutic and higher doses. The invention also provides compositions comprising such polypeptides, methods of identifying, screening and synthesizing such polypeptides, and methods of treating, preventing or diagnosing diseases and disorders associated with dyslipidemia, hypercholesterolemia, or inflammation; or diseases involving abnormal glucose metabolism, e.g., diabetes, metabolic syndrome; or Alzheimer's Disease or frontotemporal dementia. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/774682 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 45/06 (20130101) A61K 47/48053 (20130101) Peptides C07K 14/435 (20130101) Original (OR) Class C07K 14/775 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017753 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Yu Zhang (Beijing, China PRC); Junxin Duan (Beijing, China PRC); Lan Tang (Beijing, China PRC) |
| ABSTRACT | The present invention provides isolated polypeptides having cellulolytic enhancing activity and polynucleotides encoding the polypeptides. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Friday, September 28, 2012 |
| APPL NO | 14/347475 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/14 (20130101) C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017755 | Morant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NOVOYZMES, INC. (Davis, California) |
| ASSIGNEE(S) | NOVOZYMES, INC. (Davis, California) |
| INVENTOR(S) | Marc D. Morant (Bagsvaerd, Denmark); Paul Harris (Davis, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/235409 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 21/00 (20130101) C12P 2201/00 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 302/01091 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017760 | Gill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Inscripta, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | Inscripta, Inc. (Boulder, Colorado); The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Ryan T. Gill (Denver, Colorado); Andrew Garst (Boulder, Colorado); Tanya Elizabeth Warnecke Lipscomb (Boulder, Colorado); Marcelo Colika Bassalo (Boulder, Colorado); Ramsey Ibrahim Zeitoun (San Francisco, California) |
| ABSTRACT | Provided herein are methods and composition for trackable genetic variant libraries. Further provided herein are methods and compositions for recursive engineering. Further provided herein are methods and compositions for multiplex engineering. Further provided herein are methods and compositions for enriching for editing and trackable engineered sequences and cells using nucleic acid-guided nucleases. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 15/632222 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/102 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1079 (20130101) C12N 15/1082 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017770 | Tuskan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Gerald A. Tuskan (Oak Ridge, Tennessee); Xiaohan Yang (Knoxville, Tennessee); Henrique Cestari De Paoli (Oak Ridge, Tennessee) |
| ABSTRACT | Disclosed herein are vectors and components for a nucleic acid cloning system, and methods of use of the vectors and components in cloning nucleic acid fragments of interest. The cloning system includes two families of destination vectors which can be used in alternating form to systematically combine nucleic acid fragments of interest. |
| FILED | Wednesday, July 01, 2015 |
| APPL NO | 14/789112 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) Original (OR) Class C12N 15/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017792 | Beckham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Gregg T. Beckham (Denver, Colorado); Christopher W. Johnson (Denver, Colorado); Derek R. Vardon (Lakewood, Colorado); Mary Ann Franden (Centennial, Colorado) |
| ABSTRACT | This disclosure relates to compositions and methods for converting biomass to various chemical intermediates and final products including fuels. Aspects include the depolymerization of lignin, cellulose, and hemicellulose to a wide slate of depolymerization compounds that can be subsequently metabolized by genetically modified bacterium, and converted to cis,cis-muconic acid. Other aspects include the use of monometallic catalysts for converting the cis,cis-muconic acid to commodity chemicals and fuels, for example adipic acid and/or nylon. |
| FILED | Monday, July 20, 2015 |
| APPL NO | 14/804161 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/36 (20130101) C07C 51/36 (20130101) C07C 51/43 (20130101) C07C 51/43 (20130101) C07C 51/47 (20130101) C07C 51/47 (20130101) C07C 55/14 (20130101) C07C 57/16 (20130101) C07C 57/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class Enzymes C12Y 113/11001 (20130101) C12Y 401/01063 (20130101) C12Y 402/01118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017793 | Grabar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Myriant Corporation (Woburn, Massachusetts) |
| ASSIGNEE(S) | Myriant Corporation (Woburn, Massachusetts) |
| INVENTOR(S) | Tammy Grabar (North Reading, Massachusetts); Wei Gong (Woburn, Massachusetts); R. Rogers Yocum (Lexington, Massachusetts) |
| ABSTRACT | This invention relates to the metabolic evolution of a microbial organism previously optimized for producing an organic acid in commercially significant quantities under fermentative conditions using a hexose sugar as sole source of carbon in a minimal mineral medium. As a result of this metabolic evolution, the microbial organism acquires the ability to use pentose sugars derived from cellulosic materials for its growth while retaining the original growth kinetics, the rate of organic acid production and the ability to use hexose sugars as a source of carbon. This invention also discloses the genetic change in the microorganism that confers the ability to use both the hexose and pentose sugars simultaneously in the production of commercially significant quantities of organic acids. |
| FILED | Friday, September 19, 2014 |
| APPL NO | 14/491073 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/93 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/46 (20130101) Original (OR) Class C12P 2203/00 (20130101) Enzymes C12Y 207/03009 (20130101) C12Y 401/01031 (20130101) C12Y 401/01032 (20130101) C12Y 604/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017842 | Holcomb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | David E. Holcomb (Oak Ridge, Tennessee); Govindarajan Muralidharan (Knoxville, Tennessee); Dane F. Wilson (Oak Ridge, Tennessee) |
| ABSTRACT | An essentially Fe-free alloy consists essentially of, in terms of weight percent: 4 to 11 Co, 6.5 to 7.5 Cr, 0 to 0.15 Al, 0.5 to 0.85 Mn, 11 to 20 Mo, 1 to 3.5 Ta, 0.05 to 9 W, 0.03 to 0.08 C, 0 to 0.001 B, 0.0005 to 0.005 N, balance Ni, the alloy being characterized by, at 850° C., a yield strength of at least 25 Ksi, a tensile strength of at least 45 Ksi, a creep rupture life at 12 Ksi of at least 10 hours, and a corrosion rate, expressed in weight loss [g/(cm2sec)]10−11 during a 1000 hour immersion in liquid FLiNaK at 850° C., in the range of 5 to 20. |
| FILED | Monday, August 05, 2013 |
| APPL NO | 13/958672 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 19/007 (20130101) C22C 19/057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017843 | Mariani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Robert D Mariani (Idaho Falls, Idaho); Douglas L Porter (Idaho Falls, Idaho) |
| ABSTRACT | A composition includes a metal alloy matrix comprising iron and a plurality of nanoparticles dispersed within the metal alloy matrix. Each nanoparticle of the plurality comprises an oxide of a rare-earth metal and at least one metal selected from the group consisting of tantalum, niobium, vanadium, and titanium. Some compositions include a metal alloy matrix comprising iron and a plurality of nanoparticles comprising at least two different oxides of rare-earth metals dispersed within the metal alloy matrix. Some methods include mixing an oxide of a rare-earth metal with a first metal and a second metal. Other methods include mixing a plurality of particles comprising at least one oxide of a rare-earth metal with a molten metal comprising iron. Each particle of the plurality may exhibit a density between about 6.9 g/cm3 and about 9.0 g/cm3. |
| FILED | Tuesday, March 25, 2014 |
| APPL NO | 14/225306 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 32/0026 (20130101) Original (OR) Class C22C 33/00 (20130101) C22C 33/04 (20130101) C22C 38/02 (20130101) C22C 38/04 (20130101) C22C 38/22 (20130101) C22C 38/24 (20130101) C22C 38/26 (20130101) C22C 38/28 (20130101) C22C 38/44 (20130101) C22C 38/46 (20130101) C22C 38/48 (20130101) C22C 38/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017867 | Gesing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Phinix, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | PHINIX, LLC (Clayton, Missouri) |
| INVENTOR(S) | Adam J. Gesing (Tecumseh, Canada); Subodh Das (Lexington, Kentucky); Mark Adam Gesing (Hamilton, Canada) |
| ABSTRACT | The invention comprises methods and apparatuses for the electrorefining of Mg from Al or Mg alloy scrap. The invention utilizes the density and charge features of Mg present in a melted alloy to continuously extract Mg and Mg alloys from a melted Al alloy feed. |
| FILED | Friday, February 13, 2015 |
| APPL NO | 14/621759 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/65 (20130101) C04B 35/581 (20130101) C04B 35/581 (20130101) C04B 35/634 (20130101) C04B 35/638 (20130101) C04B 35/58071 (20130101) C04B 38/06 (20130101) C04B 38/06 (20130101) C04B 38/0058 (20130101) C04B 2111/00612 (20130101) C04B 2111/00793 (20130101) C04B 2111/00853 (20130101) C04B 2235/46 (20130101) C04B 2235/48 (20130101) C04B 2235/402 (20130101) C04B 2235/666 (20130101) C04B 2235/3865 (20130101) C04B 2235/5427 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 26/22 (20130101) Alloys C22C 1/02 (20130101) C22C 23/02 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/00 (20130101) C25C 3/04 (20130101) C25C 3/36 (20130101) C25C 7/005 (20130101) C25C 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018025 | Ciezobka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
| ASSIGNEE(S) | GAS TECHNOLOGY INSTITUTE (Des Plaines, Illinois) |
| INVENTOR(S) | Jordan Ciezobka (Addison, Illinois); Iraj Salehi (Naperville, Illinois) |
| ABSTRACT | A hydraulic fracturing system and method for enhancing effective permeability of earth formations to increase hydrocarbon production, enhance operation efficiency by reducing fluid entry friction due to tortuosity and perforation, and to open perforations that are either unopened or not effective using traditional techniques, by varying a pump rate and/or a flow rate to a wellbore. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/445044 |
| ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018128 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Ko-Jen Wu (West Bloomfield, Michigan); Oliver Rudwinsky (Oakland, Michigan); Robert S. McAlpine (Lake Orion, Michigan) |
| ABSTRACT | An engine control system includes an internal combustion engine including a plurality of cylinders. An intake manifold is connected to the internal combustion engine. An exhaust manifold is connected to the internal combustion engine. A supercharger is connected to an air intake passage and the intake manifold and includes a variable speed drive. A throttle valve is disposed in the air intake passage. An exhaust passage is in connection with the exhaust manifold. A passive selective catalytic reduction catalyst system is in communication with the exhaust passage. An exhaust gas recirculation passage is in communication with the exhaust passage and the air intake passage and includes an exhaust gas recirculation valve. A controller controls the variable speed drive of the supercharger and the throttle valve and the exhaust gas recirculation valve based upon engine conditions. |
| FILED | Thursday, August 04, 2016 |
| APPL NO | 15/228301 |
| ART UNIT | 3748 — AI & Simulation/Modeling |
| CURRENT CPC | Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/2066 (20130101) F01N 13/10 (20130101) F01N 2610/02 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 39/04 (20130101) Controlling Combustion Engines F02D 41/0007 (20130101) Original (OR) Class F02D 2041/0017 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 26/02 (20160201) F02M 26/14 (20160201) F02M 26/17 (20160201) F02M 26/52 (20160201) F02M 35/104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018353 | Chiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GENERAL ELECTRIC TECHNOLOGY GMBH (Baden, Switzerland) |
| ASSIGNEE(S) | GENERAL ELECTRIC TECHNOLOGY GMBH (Baden, Switzerland) |
| INVENTOR(S) | John H. Chiu (West Hartford, Connecticut); Bard C. Teigen (Enfield, Connecticut) |
| ABSTRACT | A sealpot for a combustion power plant includes a downcomer standpipe which receives solids of the combustion power plant, a bed including a first end and a second opposite end, the first end connected to the downcomer standpipe, a discharge standpipe disposed at the second opposite end of the bed, and an orifice plate disposed between the bed and the discharge standpipe separating the discharge standpipe from the bed. The orifice plate includes apertures disposed at a height above the bed which allow transport of fluidized solids and gas through the orifice plate. |
| FILED | Thursday, September 17, 2015 |
| APPL NO | 14/856897 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 10/02 (20130101) F23C 10/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018577 | Koch |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Security Technologies, LLC (Las Vegas, Nevada) |
| ASSIGNEE(S) | Mission Support and Tests Services, LLC (North Las Vegas, Nevada) |
| INVENTOR(S) | Jeffrey A. Koch (Livermore, California) |
| ABSTRACT | A method and apparatus for imaging the distribution of bulk motional velocities in plasmas such as inertial confinement fusion (ICF) implosions. This method and apparatus use multiple narrow-band x-ray crystal imaging systems, one or more of which have a bandpass tuned to lie within the Doppler-broadened emission line profile of a suitable plasma emission line. Crystals tuned on the one end of the profile will preferentially reflect x-rays from plasma ions moving towards the crystals, while crystals tuned to another end of the profile will preferentially reflect x-rays from plasma ions moving away from the crystals. |
| FILED | Monday, April 04, 2016 |
| APPL NO | 15/090408 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2076 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018583 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (Wuhan, Hubei, China PRC) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); Huazhong University of Science and Technology (Wuhan, China PRC) |
| INVENTOR(S) | Yingchao Yu (Ithaca, New York); Héctor D. Abruña (Ithaca, New York); Deli Wang (Hubei, China PRC); Weidong Zhou (Ithaca, New York); Liu Hongfang (Hubei, China PRC); Qin Shuang (Hubei, China PRC) |
| ABSTRACT | A method for preparing a material composition comprising a hollow transition metal oxide nanoparticle supported upon a carbon material support includes a solution impregnation process step, followed by a thermal reduction process step and finally a thermal oxidation process step. The material composition, an electrode and an electrical component such as but not limited to a battery are all predicated at least in-part upon the material composition prepared in accord with the foregoing method. The foregoing material composition, electrode, battery and method may ultimately provide a LIB with enhanced performance. |
| FILED | Friday, March 21, 2014 |
| APPL NO | 14/778129 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/30 (20130101) H01G 11/32 (20130101) H01G 11/46 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/362 (20130101) H01M 4/366 (20130101) H01M 4/0416 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/583 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018592 | Ibrahim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Yehia M. Ibrahim (West Richland, Washington); Sandilya Garimella (Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Methods and apparatuses for ion peak compression and increasing resolution of ions are disclosed. Packets of ions are introduced into a device. A first electric field is applied for dispersing the ion packets temporally or spatially according to their mobilities. A second intermittent traveling wave is applied for regrouping or merging the dispersed ion packets into a lesser number of trapping regions with narrower peaks. The ions packets are compressed into the narrower peak regions by varying a duty cycle of the intermittent traveling wave. |
| FILED | Tuesday, May 17, 2016 |
| APPL NO | 15/157217 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018615 | Qian et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Fang Qian (Santa Cruz, California); Mihail Bora (Livermore, California); Eric Duoss (Dublin, California); Christopher Spadaccini (Oakland, California); Cheng Zhu (Livermore, California) |
| ABSTRACT | Disclosed here is a three-dimensional electronic scaffold, comprising a porous scaffold and a plurality of micro-strain gauges distributed spatially inside the porous scaffold, wherein the micro-strain gauges are adapted to detect contraction force. Also disclosed is a method comprising detecting and mapping intra-tissue cardiac contraction force of one or more cardiac cells or tissues disposed in a three-dimensional electronic scaffold, wherein the three-dimensional electronic scaffold comprises a porous scaffold and a plurality of micro-strain gauges distributed spatially inside the porous scaffold and in contact with the cardiac cells or tissues, and wherein the micro-strain gauges are adapted to detect contraction force of the cardiac cells or tissues. |
| FILED | Tuesday, March 08, 2016 |
| APPL NO | 15/064044 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 2513/00 (20130101) C12N 2533/00 (20130101) C12N 2533/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Original (OR) Class G01N 33/5082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018718 | Musgrove et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Cameron Musgrove (Albuquerque, New Mexico); Richard M. Naething (Albuquerque, New Mexico); Richard C. Ormesher (Albuquerque, New Mexico) |
| ABSTRACT | The various technologies presented herein relate to reducing and/or filtering undesired artifacts in a SAR image, wherein the artifacts are generated by RF interference resulting from a communication signal being included in a radar return which also comprises radar clutter. The radar return is separated into two subapertures, a first subaperture comprising radar clutter only, and a second subaperture comprising radar clutter and the communication signal. The communication signal is extracted from the second subaperture and reapplied to the initially received radar return. Reapplication of the communication signal to the radar return enables any undesired artifacts arising from the communication signal to have their return strength reduced or minimized, while maintaining any desired radar returns in the SAR image. |
| FILED | Thursday, October 29, 2015 |
| APPL NO | 14/927130 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/292 (20130101) G01S 13/9035 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018739 | Henry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Nathaniel F. Henry (Clinton, Tennessee); Alexander K. Moses (Knoxville, Tennessee) |
| ABSTRACT | A curved vacuum cassette assembly including a rigid or semi-rigid curved structural backing that is porous or semi-porous to air flow such that one or more imaging detectors (e.g. film layers or CR plates), intensifying screens, and/or other layers may be affixed to the curved structural backing in a secure and conformal manner when a vacuum is applied to the structural backing. All of these structures are encapsulated within an airtight barrier and, optionally, another suitable rigid or semi-rigid housing. |
| FILED | Monday, February 27, 2017 |
| APPL NO | 15/443403 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/16 (20130101) G01T 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018824 | Reed |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integrated Dynamic Electron Solutions, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | INTEGRATED DYNAMIC ELECTRON SOLUTIONS, INC. (Pleasanton, California) |
| INVENTOR(S) | Bryan W. Reed (San Leandro, California) |
| ABSTRACT | Methods and systems for temporal compressive sensing are disclosed, where within each of one or more sensor array data acquisition periods, one or more sensor array measurement datasets comprising distinct linear combinations of time slice data are acquired, and where mathematical reconstruction allows for calculation of accurate representations of the individual time slice datasets. |
| FILED | Friday, November 03, 2017 |
| APPL NO | 15/802876 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/225 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/003 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) H01J 37/222 (20130101) H01J 37/265 (20130101) H01J 2237/221 (20130101) H01J 2237/226 (20130101) H01J 2237/262 (20130101) H01J 2237/2802 (20130101) H01J 2237/24455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019176 | Yoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Doe Hyun Yoon (San Jose, California); Naveen Muralimanohar (Santa Clara, California); Jichuan Chang (Sunnyvale, California); Parthasarathy Ranganathan (San Jose, California) |
| ABSTRACT | An example method involves receiving, at a first memory node, data to be written at a memory location in the first memory node. The data is received from a device. At the first memory node, old data is read from the memory location, without sending the old data to the device. The data is written to the memory location. The data and the old data are sent from the first memory node to a second memory node to store parity information in the second memory node without the device determining the parity information. The parity information is based on the data stored in the first memory node. |
| FILED | Tuesday, October 30, 2012 |
| APPL NO | 14/417220 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/065 (20130101) G06F 3/0619 (20130101) Original (OR) Class G06F 3/0655 (20130101) G06F 3/0656 (20130101) G06F 3/0665 (20130101) G06F 3/0688 (20130101) G06F 3/0689 (20130101) G06F 11/108 (20130101) G06F 2211/1054 (20130101) G06F 2211/1066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019235 | Nordholt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Jane Elizabeth Nordholt (Los Alamos, New Mexico); Richard John Hughes (Los Alamos, New Mexico); Raymond Thorson Newell (Santa Fe, New Mexico); Charles Glen Peterson (Los Alamos, New Mexico); Alexander Rosiewicz (Stow, Massachusetts) |
| ABSTRACT | Random number generators include a thermal optical source and detector configured to produce random numbers based on quantum-optical intensity fluctuations. An optical flux is detected, and signals proportional to optical intensity and a delayed optical intensity are combined. The combined signals can be electrical signals or optical signals, and the optical source is selected so as to have low coherence over a predetermined range of delay times. Balanced optical detectors can be used to reduce common mode noise, and in some examples, the optical flux is directed to only one of a pair of balanced detectors. |
| FILED | Wednesday, July 29, 2015 |
| APPL NO | 14/812623 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/588 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0852 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019565 | Ewing |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Daniel Jonathan Ewing (Overland Park, Kansas) |
| ABSTRACT | A method and apparatus for reading unique identifiers of an integrated circuit. The unique identifiers may be physically unclonable functions (PUFs), formed by high energy ions implanted into semiconductor material of the integrated circuit. The method may include electrically or optically stimulating each of the PUFs and sensing with an optical sensor optical characteristics of resulting light emitted from the PUFs. Then the method may include comparing values associated with the optical characteristics of the PUFs with groups of stored values in a circuit database. Each of the groups of stored values may be associated with optical characteristics of PUFs of a known authentic circuit. The method may then include the controller providing verification of authenticity of the integrated circuit when each of the values associated with the optical characteristics of the PUFs match the stored values of at least one of the groups in the circuit database. |
| FILED | Thursday, December 17, 2015 |
| APPL NO | 14/973383 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/66 (20130101) G01N 21/6489 (20130101) G01N 2201/12 (20130101) Electric Digital Data Processing G06F 21/44 (20130101) Original (OR) Class G06F 21/45 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019824 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Randy S. Roberts (Livermore, California); John Goforth (Carlsbad, California) |
| ABSTRACT | An annotation system for providing annotations for original images is provided. In some embodiments, the annotation system accesses an annotation associated with an object of a 3D model. The annotation system also accesses and displays an original image. The annotation system renders a model image of the 3D model based on the view from which the original image was collected. When the model image contains the annotated object, the annotation system provides an indication that an annotation is associated with the object of the original image. The annotation system can provide indications of the annotation for other original images that include the annotated object irrespective of the view from which the other original images are collected. |
| FILED | Tuesday, August 16, 2016 |
| APPL NO | 15/238550 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/241 (20130101) Image Data Processing or Generation, in General G06T 3/0068 (20130101) G06T 11/60 (20130101) Original (OR) Class G06T 17/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020235 | Voss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Lars Voss (Livermore, California); Adam Conway (Livermore, California); Robert T. Graff (Modesto, California); Art Nelson (Livermore, California); Rebecca J. Nikolic (Oakland, California); Stephen A. Payne (Castro Valley, California); Erik Lars Swanberg, Jr. (Livermore, California) |
| ABSTRACT | In various approaches room-temperature gamma detector longevity may be improved by selectively removing, or selectively incorporating, alternate halogen component(s) from select surfaces of the detector. According to one embodiment, a method of improving operational longevity of a thallium bromide (TlBr)-based detector includes: selectively treating one or more surfaces of the TlBr-based detector to produce a surface substantially comprising pure TlBr. Similar techniques may be employed to restore a degraded or failed detector. According to another embodiment, a method of forming a TlBr-based detector exhibiting improved operational longevity includes: selectively treating one or more surfaces of the TlBr-based detector to replace Br therein with one or more alternate halogen components while also substantially avoiding replacing some or all of the Br in other surfaces of the TlBr-based detector with the one or more alternate halogen components. Corresponding structures for TlBr-based detectors with improved longevity are also described. |
| FILED | Tuesday, November 01, 2016 |
| APPL NO | 15/340849 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/20 (20130101) Original (OR) Class H01L 31/18 (20130101) H01L 31/032 (20130101) H01L 31/085 (20130101) H01L 31/035272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020479 | Mikhaylik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sion Power Corporation (Tucson, Arizona) |
| ASSIGNEE(S) | Sion Power Corporation (Tucson, Arizona) |
| INVENTOR(S) | Yuriy V. Mikhaylik (Tucson, Arizona); Michael G. Laramie (Tucson, Arizona); David Child (Tucson, Arizona) |
| ABSTRACT | Articles and methods for protection of electrodes in electrochemical cells, including protective material precursor layers for use in electrode protective structures, are provided. Certain embodiments relate to electrode protective structures that comprise protective material precursor layers that, upon direct contact with a liquid electrolyte, cause a reaction product to form between the material of the precursor layer and a component of the electrolyte. |
| FILED | Friday, August 08, 2014 |
| APPL NO | 14/455230 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1646 (20130101) H01M 2/1673 (20130101) H01M 2/1686 (20130101) Original (OR) Class H01M 4/62 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 10/052 (20130101) H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/4235 (20130101) H01M 2004/027 (20130101) H01M 2200/00 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020491 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Envia Systems, Inc. (Newark, California) |
| ASSIGNEE(S) | Zenlabs Energy, Inc. (Fremont, California) |
| INVENTOR(S) | Yongbong Han (San Francisco, California); Charan Masarapu (Fremont, California); Haixia Deng (Fremont, California); Yogesh Kumar Anguchamy (Newark, California); Subramanian Venkatachalam (Pleasanton, California); Herman A. Lopez (Sunnyvale, California) |
| ABSTRACT | Silicon based anode active materials are described for use in lithium ion batteries. The silicon based materials are generally composites of nanoscale elemental silicon with stabilizing components that can comprise, for example, silicon oxide-carbon matrix material, inert metal coatings or combinations thereof. High surface area morphology can further contribute to the material stability when cycled in a lithium based battery. In general, the material synthesis involves a significant solution based processing step that can be designed to yield desired material properties as well as providing convenient and scalable processing. |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 13/864212 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) C01B 33/113 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 35/532 (20130101) C04B 35/571 (20130101) C04B 35/806 (20130101) C04B 2235/80 (20130101) C04B 2235/425 (20130101) C04B 2235/428 (20130101) C04B 2235/441 (20130101) C04B 2235/5288 (20130101) C04B 2235/5409 (20130101) C04B 2235/5445 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/362 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/483 (20130101) H01M 4/625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020493 | Parans Paranthaman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Mariappan Parans Paranthaman (Knoxville, Tennessee); Craig A. Bridges (Oak Ridge, Tennessee); Sukeun Yoon (Daejeon, South Korea); Xiao-Guang Sun (Knoxville, Tennessee); Sheng Dai (Knoxville, Tennessee) |
| ABSTRACT | Compositions and methods of making are provided for coated electrodes and batteries comprising the same. The compositions may comprise a base composition having an active material selected from the group consisting of LiCoO2, LiMn2O4, Li2MnO3, LiNiO2, LiMn1.5Ni0.5O4, LiFePO4, Li2FePO4F, Li3CoNiMnO6, Li(LiaNixMnyCoz)O2, and mixtures thereof. The compositions may also comprise a coating composition that covers at least a portion of the base composition, wherein the coating composition comprises a non-metal or metalloid element. The methods of making comprise providing the base composition and a doped carbon coating composition, and mixing the coating composition with the base electrode composition at an elevated temperature in a flowing inert gas atmosphere. The coating composition may be a nitrogen-doped carbon composition a nitrogen doping element selected from the group consisting of: pyridine, 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide, 1-ethyl-3-methylimidazolium dicyanamide, and mixtures thereof. |
| FILED | Friday, October 05, 2012 |
| APPL NO | 13/645779 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/60 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/602 (20130101) H01M 4/5825 (20130101) H01M 2010/4292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020538 | Liao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Chen Liao (Willowbrook, Illinois); Trevor L. Dzwiniel (Carol Stream, Illinois); Baofei Pan (Woodridge, Illinois); Sang-Don Han (Woodridge, Illinois); Anthony Burrell (Naperville, Illinois) |
| ABSTRACT | Methods for preparing electrolyte salts for alkaline earth metal-ion batteries (e.g., calcium and magnesium ion batteries) are described. The electrolyte salts comprise alkaline earth metal (e.g., Mg or Ca) salts of bis(fluorosulfonyl)imide (FSI) and 3,4-dicyano-2-trifluoromethylimidazole (TDI). The methods comprise contacting FSI or TDI with an alkaline earth metal bis(trifluoroacetate) salt in trifluoroacetic acid. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 14/940667 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/084 (20130101) C01B 21/086 (20130101) Heterocyclic Compounds C07D 233/90 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0563 (20130101) H01M 10/0568 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020634 | Wanke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael Wanke (Albuquerque, New Mexico); Christopher Nordquist (Albuquerque, New Mexico); Mark Lee (Plano, Texas) |
| ABSTRACT | A Schottky diode is monolithically integrated into the core of an infrared semiconductor laser (e.g., a quantum cascade laser) to create a heterodyned infrared transceiver. The internal mode field of the infrared semiconductor laser couples to an embedded Schottky diode and can mix the infrared fields to generate a response at the difference frequency. |
| FILED | Thursday, December 18, 2014 |
| APPL NO | 14/575430 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/22 (20130101) H01S 5/0261 (20130101) Original (OR) Class H01S 5/343 (20130101) H01S 5/0604 (20130101) H01S 5/2054 (20130101) H01S 5/3401 (20130101) H01S 5/4025 (20130101) H01S 2301/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020968 | Rodenbeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Jose Silva-Martinez (College Station, Texas); Aydin I. Karsilayan (College Station, Texas); John Mincey (College Station, Texas) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Christopher T. Rodenbeck (Albuquerque, New Mexico); Jose Silva-Martinez (College Station, Texas); Aydin I. Karsilayan (College Station, Texas); John Mincey (College Station, Texas) |
| ABSTRACT | Described herein are various technologies relating to processing a coherent signal. A receiver is configured to receive an analog signal, and process the analog signal to generate an input analog signal. The input analog signal has been modulated according to a suitable modulation sequence. A coherent signal sampler coherently samples the modulation sequence, and the result of such sampling is in turn used to demodulate the input analog signal. The resultant signal is then passed to a sigma delta modulator, where it is converted to digital form. |
| FILED | Wednesday, March 18, 2015 |
| APPL NO | 14/662106 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/288 (20130101) G01S 19/14 (20130101) Transmission H04B 1/12 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/02 (20130101) H04L 27/227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10016130 | Ganesan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Deepak Ganesan (Amherst, Massachusetts); Benjamin M. Marlin (Amherst, Massachusetts); Addison Mayberry (Fallon, Nevada); Christopher Salthouse (Newton, Massachusetts) |
| ABSTRACT | An improved eye tracker system and methods for detecting eye parameters including eye movement using a pupil center, pupil diameter (i.e., dilation), blink duration, and blink frequency, which may be used to determine a variety of physiological and psychological conditions. The eye tracker system and methods operates at a ten-fold reduction in power usage as compared to current system and methods. Furthermore, eye tracker system and methods allows for a more optimal use in variable light situations such as in the outdoors and does not require active calibration by the user. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/257868 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/10 (20130101) A61B 3/032 (20130101) A61B 3/113 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 27/0093 (20130101) G02B 2027/0178 (20130101) G02B 2027/0187 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10016756 | Lopez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Gabriel P. Lopez (Durham, North Carolina) |
| ABSTRACT | A kit for detection of an analyte of interest in a liquid sample, and methods of using, are provided. The kit may include a pipette and a disposable pipette tip configured to engage the pipette. The pipette tip may define an acoustic channel configured for allowing flow-through of a liquid. The kit may also include a vibratory device in communication with the acoustic channel and configured for imparting a vibratory force thereto. The impartation of the vibratory force may create standing acoustic waves, thereby separating any negative acoustic contrast particles (NACPs) from the remaining contents of the liquid sample. The NACPs may capable of biospecific recognition of the analyte of interest, thereby separating the analytes of interest, which can then be collected or analyzed accordingly. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/466998 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0275 (20130101) Original (OR) Class B01L 2300/0858 (20130101) B01L 2400/0433 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 2001/4094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017388 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Yanfeng Jiang (Arlington, Massachusetts); Khetpakorn Chakarawet (Cambridge, Massachusetts); Julia Megan Stauber (Cambridge, Massachusetts); Christopher Colin Cummins (Dorchester, Massachusetts) |
| ABSTRACT | Dihydrogen metaphosphate can be synthesized via protonation, and can react with a dehydrating agent to afford tetrametaphosphate anhydride. A monohydrogen tetra-metaphosphate organic ester can be derived from the anhydride. A metal tetrametaphosphate complex can be prepared using a metal salt and a dihydrogen tetrametaphosphate. |
| FILED | Friday, June 05, 2015 |
| APPL NO | 15/312658 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 25/44 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 43/225 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/1415 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/16 (20130101) Steroids C07J 9/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017396 | Thomas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| ASSIGNEE(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| INVENTOR(S) | Evan Thomas (Lexington, Kentucky); Kristen Baroudi (Lexington, Kentucky); Yong Bok Go (Lexington, Kentucky); Robert Nordsell (Lexington, Kentucky); Jonathan Melman (Lexington, Kentucky) |
| ABSTRACT | A luminescent composition of matter is characterized by the formula REM2+xEy, where RE may be one or more Rare Earth elements (for example, Eu or Gd), M may be one or more elements selected from the group Al, Ga, B, In, Sc, Lu, and Y; E is one or more elements selected from the group S, Se, O, and Te; x is greater than zero; and y has the value that achieves charge balance in the formula assuming that E has a charge of −2. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591629 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/76 (20130101) C01F 17/0012 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/77 (20130101) C09K 11/7701 (20130101) C09K 11/7728 (20130101) C09K 11/7729 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2021/6417 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/502 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/0803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017462 | Moon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joong Ho Moon (Weston, Florida); Md Salauddin Ahmed (Comilla, Bangladesh) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Joong Ho Moon (Weston, Florida); Md Salauddin Ahmed (Comilla, Bangladesh) |
| ABSTRACT | A poly(guanylurea) (PGU), comprising the structure where a multiplicity of repeating units are connected by guanylurea groups. The repeating units comprise: linear or cyclic alkylene, heteroatom interrupted alkylene, cycloalkylene, arylene, or heteroarylene; and a linear or cyclic alkylene, one or more heteroatom interrupted alkylene, cycloalkylene, arylene, heteroarylene, or a dinitrogen heterocycle. The PGU can be used as an antimicrobial agent with low toxicity in a pharmaceutical composition, generally as a protonated PGU upon combining with a pharmaceutically acceptable acid. |
| FILED | Monday, March 05, 2018 |
| APPL NO | 15/911299 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 279/24 (20130101) Original (OR) Class Heterocyclic Compounds C07D 241/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017545 | DeShong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Philip R. DeShong (Silver Spring, Maryland); Lenea Stocker (Silver Spring, Maryland); Daniel C. Stein (Silver Spring, Maryland); Stefanie N. Vogel (Columbia, Maryland); Katharina Richard (Catonsville, Maryland) |
| ABSTRACT | The disclosure relates to compositions, pharmaceutical compositions, vaccines, and methods of making and using the same. The compositions of the disclosure are useful to stimulate an antigen-specific immune response and, in some embodiments, a protective immune response in an animal after challenge to pathogens. The compositions of the disclosure are also useful for treatment and prevention of disease in a subject such as cancer. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/295306 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/095 (20130101) A61K 39/0208 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/22 (20130101) C07K 14/195 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017632 | Aksay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Ilhan A. Aksay (Princeton, New Jersey); David L. Milius (Princeton, New Jersey); Sibel Korkut (Princeton, New Jersey); Robert K. Prud'Homme (Princeton, New Jersey) |
| ABSTRACT | Functionalized graphene sheets having a carbon to oxygen molar ratio of at least about 23:1 and method of preparing the same. |
| FILED | Tuesday, November 29, 2016 |
| APPL NO | 15/362914 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/192 (20170801) C01B 32/194 (20170801) C01B 2204/22 (20130101) C01B 2204/30 (20130101) C01B 2204/32 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/70 (20130101) C01P 2006/10 (20130101) C01P 2006/12 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/042 (20170501) C08K 9/00 (20130101) Original (OR) Class C08K 2201/001 (20130101) C08K 2201/006 (20130101) Compositions of Macromolecular Compounds C08L 27/18 (20130101) C08L 71/123 (20130101) C08L 77/06 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/62 (20180101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) H01B 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017728 | Jewett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Brian Robert Fritz (Chicago, Illinois); Laura Elyse Timmerman (Chicago, Illinois); Yi Liu (Chicago, Illinois) |
| ABSTRACT | A platform for preparing a sequence defined biopolymer in vitro is disclosed. The platform includes a ribosome-depleted cellular extract ribosomal RNAs prepared by in vitro transcription and purified ribosomal proteins depleted of ribosomal RNAs. A method of synthesizing and assembling ribosomes in vitro for use in the platform is provided, as well as a method for preparing a sequence defined biopolymer in vitro using assembling ribosomes and the platform. |
| FILED | Thursday, April 24, 2014 |
| APPL NO | 14/786972 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) C12P 21/00 (20130101) C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017757 | Daugherty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Patrick Sean Daugherty (Santa Barbara, California); Kevin Todd Boulware (Pasadena, California) |
| ABSTRACT | The present invention provides compositions including peptide display scaffolds that present at least one candidate peptide and at least one detectable moiety in at least one of the N-terminal and C-terminal candidate peptide presenting domains that when expressed in a cell are accessible at a surface of the cell outermembrane. In addition, the present invention also provides kits and methods for screening a library of cells presenting the candidate peptides in peptide display scaffolds to identify a ligand for an enzyme. |
| FILED | Tuesday, July 21, 2015 |
| APPL NO | 14/805284 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/245 (20130101) C07K 2319/03 (20130101) C07K 2319/22 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) C12N 15/1044 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/02 (20130101) C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017773 | Pajerowska-Mukhtar et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Karolina M. Pajerowska-Mukhtar (Vestavia Hills, Alabama); Guoyong Xu (Durham, North Carolina); Xinnian Dong (Durham, North Carolina) |
| ABSTRACT | The present invention relates to new methods to study and control the expression of plant genes, particularly nucleotide sequences located downstream from regions comprising binding sites for transcription factors, such as the cis-element translocon 1 (TL1) comprising GAAGAAGAA and similar sequences. The invention relates to isolated nucleotide sequences comprising a regulatory region comprising a promoter operably-linked to one or more upstream open reading frames (uORFs) and one or more downstream open reading frames (dORFs) encoding one or more functional polypeptides, including transcription factors such as TBF1, reporter polypeptides, and polypeptides conferring resistance to drugs, resistance of plants viral, bacterial, or fungal pathogens, and polypeptides involved in the growth of plants. Related aspects include the use of a region which encodes one or more polypeptides designated uORF1 and uORF2 from Arabidopsis plants, natural and synthetic variants of these polypeptides, and their homologues and orthologues isolated from other plant species, including crop plants, plus vectors, cells, plant propagation material, transgenic plants, and seeds comprising nucleic acids comprising said all or portions of said regulatory region. Other aspects relate to methods of using these regulatory elements to generate and screen for transgenic plants having improved resistance microbial and viral plant pathogens, and engineered cells and plants comprising these one or more of these genetic elements to facilitate the production of proteins for use in structure/function studies, in industrial, medical, and agricultural applications, particularly in the discovery of metabolic pathways involved in the and development of disease-resistant plants. |
| FILED | Friday, December 19, 2014 |
| APPL NO | 14/576304 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/62 (20130101) C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8216 (20130101) Original (OR) Class C12N 15/8274 (20130101) C12N 15/8279 (20130101) C12N 15/8281 (20130101) C12N 15/8282 (20130101) C12N 15/8283 (20130101) C12N 15/8285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017794 | Nomura et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Christopher T. Nomura (Syracuse, New York); Ryan C. Tappel (Syracuse, New York); Qin Wang (Syracuse, New York) |
| ABSTRACT | Methods and systems for producing prescribed unit size poly(3-hydroxyalkanoate) (PHA) polymers and copolymers are provided. The methods and systems can employ recombinant bacteria that are not native producers of PHA or lack enzymes to degrade PHA once synthesized, metabolize short to long chain fatty acids without induction, and express an (R)-specific enoyl-CoA hydratase and a PHA synthase, the (R)-specific enoyl-CoA hydratase and PHA synthase having wide substrate specificities. The recombinant bacteria are fed at least one fatty acid substrate that is equal in carbon length to the prescribed or desired unit size of the PHA polymer to be produced. The prescribed unit size PHA that is produced is then isolated and/or purified. |
| FILED | Wednesday, January 09, 2013 |
| APPL NO | 14/371025 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/1029 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) Original (OR) Class C12P 7/625 (20130101) Enzymes C12Y 203/01 (20130101) C12Y 402/01017 (20130101) C12Y 402/01055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017799 | Smolke et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Christina D. Smolke (Menlo Park, California); Catherine Thodey (Mountain View, California); Isis Trenchard (Redwood City, California); Stephanie Galanie (Palo Alto, California) |
| ABSTRACT | Aspects of the invention include host cells that are engineered to produce benzylisoquinoline alkaloids (BIAs). The host cells include heterologous coding sequences for a variety of enzymes involved in synthetic pathways from starting compounds to BIAs of the host cell. Also provided are methods of producing the BIAs of interest by culturing the host cells under culture conditions that promote expression of enzymes encoded by the heterologous coding sequences of the host cells. Aspects of the invention further include compositions, e.g., host cells, starting compounds and kits, etc., that find use in methods of the invention. |
| FILED | Wednesday, November 23, 2016 |
| APPL NO | 15/360763 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0073 (20130101) C12N 9/1007 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/182 (20130101) Original (OR) Class Enzymes C12Y 121/03003 (20130101) C12Y 201/0114 (20130101) C12Y 201/01116 (20130101) C12Y 201/01128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017813 | Drndic et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Marija Drndic (Philadelphia, Pennsylvania); Kimberly Elizabeth Venta (Philadelphia, Pennsylvania); Gabriel Shemer (Jenkintown, Pennsylvania) |
| ABSTRACT | Provided are solid-state nanopore platforms for fast, electronic, label-free and high-resolution analysis of biomolecules. |
| FILED | Wednesday, March 26, 2014 |
| APPL NO | 14/781453 |
| ART UNIT | 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44743 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018525 | Celik-Butler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Zeynep Celik-Butler (Colleyville, Texas); Donald P. Butler (Colleyville, Texas) |
| ABSTRACT | In one embodiment, a self-powered tactile pressure sensor includes a flexible substrate, an array of piezoelectric crystalline nanorods each having a bottom end and a top end, the nanorods being generally perpendicular to the substrate, a top electrode that is electrically coupled to the top ends of the nanorods, and a bottom electrode that is electrically coupled to the bottom ends of the nanorods. |
| FILED | Thursday, October 30, 2014 |
| APPL NO | 15/032435 |
| ART UNIT | 2854 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/16 (20130101) G01L 5/226 (20130101) G01L 9/008 (20130101) G01L 9/0055 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/04 (20130101) H01L 41/37 (20130101) H01L 41/183 (20130101) H01L 41/1132 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10018583 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (Wuhan, Hubei, China PRC) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); Huazhong University of Science and Technology (Wuhan, China PRC) |
| INVENTOR(S) | Yingchao Yu (Ithaca, New York); Héctor D. Abruña (Ithaca, New York); Deli Wang (Hubei, China PRC); Weidong Zhou (Ithaca, New York); Liu Hongfang (Hubei, China PRC); Qin Shuang (Hubei, China PRC) |
| ABSTRACT | A method for preparing a material composition comprising a hollow transition metal oxide nanoparticle supported upon a carbon material support includes a solution impregnation process step, followed by a thermal reduction process step and finally a thermal oxidation process step. The material composition, an electrode and an electrical component such as but not limited to a battery are all predicated at least in-part upon the material composition prepared in accord with the foregoing method. The foregoing material composition, electrode, battery and method may ultimately provide a LIB with enhanced performance. |
| FILED | Friday, March 21, 2014 |
| APPL NO | 14/778129 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/24 (20130101) H01G 11/30 (20130101) H01G 11/32 (20130101) H01G 11/46 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/362 (20130101) H01M 4/366 (20130101) H01M 4/0416 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/583 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019658 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE UNIVERSITY (University Park, Pennsylvania) |
| INVENTOR(S) | James Z. Wang (State College, Pennsylvania); Yu Zhang (Chicago, Illinois); Stephen Wistar (Lemont, Pennsylvania); Michael A. Steinberg (State College, Pennsylvania); Jia Li (State College, Pennsylvania) |
| ABSTRACT | Satellite images from vast historical archives are analyzed to predict severe storms. We extract and summarize important visual storm evidence from satellite image sequences in a way similar to how meteorologists interpret these images. The method extracts and fits local cloud motions from image sequences to model the storm-related cloud patches. Image data of an entire year are adopted to train the model. The historical storm reports since the year 2000 are used as the ground-truth and statistical priors in the modeling process. Experiments demonstrate the usefulness and potential of the algorithm for producing improved storm forecasts. A preferred method applies cloud motion estimation in image sequences. This aspect of the invention is important because it extracts and models certain patterns of cloud motion, in addition to capturing the cloud displacement. |
| FILED | Wednesday, August 09, 2017 |
| APPL NO | 15/672856 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Meteorology G01W 1/00 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) G06K 9/0063 (20130101) G06K 9/66 (20130101) Original (OR) Class G06K 9/00335 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101) G06T 2207/10032 (20130101) G06T 2207/30192 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020438 | Yazdani et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Ali Yazdani (Princeton, New Jersey); Andrei Bernevig (Lawrenceville, New Jersey) |
| ABSTRACT | A magnetic topological nanowire structure comprises a superconductor and a quasi-1D magnetic nanowire. The quasi-1D magnetic nanowire is coupled to or embedded in the superconductor to produce a self-contained interaction resulting in a spatially separated pair of Majorana fermions. The pair of Majorana fermions corresponds to the topological superconductor and each of the pair of the Majorana fermions are localized near a respective endpoint of the nanowire. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 14/818002 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0072 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/12 (20130101) H01L 39/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020586 | Georgakopoulos et al. |
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| FUNDED BY |
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| APPLICANT(S) | Stavros Georgakopoulos (Boca Raton, Florida); Shun Yao (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Stavros Georgakopoulos (Boca Raton, Florida); Shun Yao (Miami, Florida) |
| ABSTRACT | A segmented helical antenna can include: a plurality of unit arms, each unit arm having a center hole, a first end hole, and a second end hole; a central axis passing through the center hole of the plurality of unit arms; a first wire passing through the first end hole of each of the plurality of unit arms; and a second wire passing through the second end hole of each of the plurality of unit arms. Each unit arm can be configured to be rotatable such that the first wire and the second wire rotate clockwise or counterclockwise. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 15/643981 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/362 (20130101) H01Q 9/145 (20130101) H01Q 11/086 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020593 | Yngvesson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sigfrid K. Yngvesson (Leverett, Massachusetts); Martin Muthee (Randolph, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Sigfrid K. Yngvesson (Leverett, Massachusetts); Martin Muthee (Randolph, Massachusetts) |
| ABSTRACT | A system that includes an electromagnetic wave transmission structure having a first end and a second end, conducting components, the conducting components selected from at least one of a network of carbon nanotubes, at least one strip of palladium, at least one strip of platinum or at least one exfoliated graphene sheet, deposited across a location in a wave transmission section of the wave transmission structure (also referred to as a gap), and at least one antenna electromagnetically coupled to the electromagnetic wave transmission structure at one of the first or second end, the antenna and the electromagnetic wave transmission structure being formed by integrated circuit techniques is disclosed. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 14/710891 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/50 (20130101) H01Q 21/0006 (20130101) Original (OR) Class H01Q 21/0087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020822 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Tong Zhang (Watervliet, New York); Hao Wang (Hefei, China PRC) |
| ABSTRACT | A system and method of providing error tolerant memory access operations on a memory device. A method is disclosed including: providing location information of weak memory cells, wherein the location information includes addresses grouped into tiered sets, wherein each tiered set includes addresses having a number of weak memory cells; receiving a target address for a memory read operation; reading data from a virtual repair memory if the target address belongs to a first tiered set of addresses having a number of weak memory cells exceeding a threshold; and if the target address does not belong the first tiered set of addresses, reading data from the memory device and alternatively performing (a) an error correction and error detection (ECED) operation and (b) a target address look up operation, at different settings, until an error free result is obtained. |
| FILED | Monday, July 20, 2015 |
| APPL NO | 15/323598 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/064 (20130101) G06F 3/0611 (20130101) G06F 3/0619 (20130101) G06F 3/0659 (20130101) G06F 3/0673 (20130101) G06F 11/1076 (20130101) Coding; Decoding; Code Conversion in General H03M 13/154 (20130101) Original (OR) Class H03M 13/1575 (20130101) H03M 13/6502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10021135 | Michaels et al. |
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| FUNDED BY |
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| APPLICANT(S) | Spencer Michaels (Miami, Florida); Kemal Akkaya (Miami, Florida); A. Selcuk Uluagac (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Spencer Michaels (Miami, Florida); Kemal Akkaya (Miami, Florida); A. Selcuk Uluagac (Miami, Florida) |
| ABSTRACT | Methods, systems, and devices for instituting a new type of attack on Zigbee networks are provided. Targeting the data-collection aspect of Zigbee's use cases, a denial-of-service attack can be implemented, and can induce loss of the data transmitted from an end device to the coordinator of the network. Such an attack can exploit the fact that the handshake for a newly joining node to the Zigbee coordinator is not encrypted. Methods, systems, and devices to mitigate such an attack are also provided. To mitigate such a type of attack, a low-overhead countermeasure can be implemented, based on a challenge-response. |
| FILED | Thursday, January 04, 2018 |
| APPL NO | 15/862073 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/18 (20130101) H04L 63/1425 (20130101) H04L 63/1483 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/80 (20180201) H04W 12/12 (20130101) H04W 76/10 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10017632 | Aksay et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Ilhan A. Aksay (Princeton, New Jersey); David L. Milius (Princeton, New Jersey); Sibel Korkut (Princeton, New Jersey); Robert K. Prud'Homme (Princeton, New Jersey) |
| ABSTRACT | Functionalized graphene sheets having a carbon to oxygen molar ratio of at least about 23:1 and method of preparing the same. |
| FILED | Tuesday, November 29, 2016 |
| APPL NO | 15/362914 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/192 (20170801) C01B 32/194 (20170801) C01B 2204/22 (20130101) C01B 2204/30 (20130101) C01B 2204/32 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/70 (20130101) C01P 2006/10 (20130101) C01P 2006/12 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/042 (20170501) C08K 9/00 (20130101) Original (OR) Class C08K 2201/001 (20130101) C08K 2201/006 (20130101) Compositions of Macromolecular Compounds C08L 27/18 (20130101) C08L 71/123 (20130101) C08L 77/06 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/62 (20180101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) H01B 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017687 | Ravi et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Vilupanur A. Ravi (Claremont, California); Samad A. Firdosy (La Crescenta, California); Jean-Pierre Fleurial (Altadena, California); Sabah K. Bux (Chino Hills, California); Andrew Kindler (San Marino, California) |
| ABSTRACT | The present invention provides a method of preparing a proppant material by heating a reaction mixture comprising a plurality of oxides in a reactive atmosphere to a temperature above the melting point of the reaction mixture to form a melt, and then allowing the melt to solidify in a mold in the form of spherical particles. The present invention also provides a method of preparing a proppant material by heating a reaction mixture comprising a plurality of oxides and one or more additives in a reactive atmosphere to a temperature below the melting point of the reaction mixture to form a powder including one or more reaction products, and then processing the powder to form spherical particles. The present invention also provides a proppant material including spherical particles characterized by a specific gravity of about 1.0 to 3.0 and a crush strength of at least about 10,000 psi. |
| FILED | Thursday, May 14, 2015 |
| APPL NO | 14/712888 |
| ART UNIT | 1768 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 33/32 (20130101) C04B 33/138 (20130101) C04B 33/323 (20130101) C04B 33/1352 (20130101) C04B 35/04 (20130101) C04B 35/04 (20130101) C04B 35/628 (20130101) C04B 35/645 (20130101) C04B 35/653 (20130101) C04B 35/58007 (20130101) C04B 35/62204 (20130101) C04B 35/62655 (20130101) C04B 38/009 (20130101) C04B 38/009 (20130101) C04B 38/0074 (20130101) C04B 2235/77 (20130101) C04B 2235/80 (20130101) C04B 2235/94 (20130101) C04B 2235/96 (20130101) C04B 2235/3217 (20130101) C04B 2235/5427 (20130101) C04B 2235/6562 (20130101) C04B 2235/6565 (20130101) C04B 2235/6586 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/80 (20130101) C09K 8/805 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 40/69 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10019835 | Skoog et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Mark Skoog (Palmdale, California); Loyd Hook (Valencia, California); Shaun McWherter (Lancaster, California); Jamie Wiley Willhite (California City, California) |
| ABSTRACT | The invention is a system and method of compressing terrain data to be used to render a three-dimensional map representation of the terrain data. In general, the invention operates by first selecting the boundaries of the terrain data and to be compressed and dividing the terrain data into regular geometric areas. Next, a type of free-edged, planar geometric surface is defined which is used to approximate the terrain data for each regular geometric area. The approximations are checked to determine if they fall within user selected tolerances. If the approximation for a specific regular geometric area is within the user specified tolerances, the data is saved for that specific regular geometric area. If the approximation for a specific regular geometric area falls outside the user specified tolerances, the regular geometric area is divided and a free-edged, planar geometric surface approximation is made for each of the divided areas. This process is recursively repeated until all of the regular geometric areas are approximated by free-edged, planar surfaces. Finally, the compressed terrain data is used to render a three-dimensional map. |
| FILED | Thursday, October 02, 2014 |
| APPL NO | 14/504614 |
| ART UNIT | 3627 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 15/10 (20130101) Original (OR) Class G06T 17/005 (20130101) G06T 17/20 (20130101) G06T 2210/12 (20130101) G06T 2210/61 (20130101) G06T 2215/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020010 | Ndao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Sidy Ndao (Lincoln, Nebraska); Mahmoud Elzouka (Lincoln, Nebraska) |
| ABSTRACT | A thermomechanical memory/logic device is disclosed. In embodiments, the thermomechanical device includes a first thermally controlled terminal (e.g., hot terminal); a second thermally controlled terminal (e.g., cool terminal/base); a stem or other structure that can be thermally expanded connected to the cool terminal; and a thermal conductive head coupled to the stem. The head can exchange heat with the hot terminal. The stem and head are between the first thermally controlled terminal and the second thermally controlled terminal, wherein the stem expands or contracts in response to heat absorbed or given off by the thermal conductive head, causing the head to move towards the first thermally controlled terminal or towards the second thermally controlled terminal until a stable state is reached. For example, bistable thermal states can be used to implement logic states (e.g., ZERO or ONE states). |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/350848 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 3/02 (20130101) Original (OR) Class G11B 9/149 (20130101) G11B 13/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020558 | Sanner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Kurt G Sanner (Tehachapi, California); Evan J Kaiser (Auburn, California) |
| ABSTRACT | The present invention is an auto tracking antenna platform upon which multiple antenna elements can be mounted to track a common moving object. The antenna tracking platform generally comprises a bottom pedestal enclosing a rotary azimuth actuator for controlled-rotary motion about the single vertical (z) axis, and an upper multi-tier framework housing a horizontal antenna-mounting beam pivotally supported for rotation about a horizontal (x) axis, and a drive assembly for direct-drive rotation of the antenna-mounting bar. Antenna elements are mounted along the horizontal mounting bar and the feeds routed through the azimuth actuator. This enables the use of fiber optic rotary joints or slip rings to pass data and video, instead of RF (waveguide) rotary joints which are required to pass high power RF signals. |
| FILED | Monday, May 18, 2015 |
| APPL NO | 14/714756 |
| ART UNIT | 3632 — Static Structures, Supports and Furniture |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/1264 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10017538 | Choi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Man-Yeon Choi (Gainesville, Florida); Robert K. Vander Meer (Newberry, Florida) |
| ABSTRACT | Disclosed are novel bioactive peptides derived as antagonists to a fire ant receptor for a pheromone biosynthesis-activating neuropeptide/pyrokinin (PBAN/pyrokinin) gene derived neuropeptide ligand. Also disclosed are methods of controlling fire ants with the bioactive peptides disclosed herein. Methodological approaches to screening peptide libraries for the presence of PBAN/pyrokinin ligands are also provided herein. |
| FILED | Tuesday, August 15, 2017 |
| APPL NO | 15/677648 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/726 (20130101) G01N 2333/43552 (20130101) G01N 2430/10 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10017771 | Handelsman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Jo Emily Handelsman (North Bradford, Connecticut); Amy Klimowicz (Madison, Wisconsin); Changhui Guan (Cheshire, Connecticut) |
| ABSTRACT | Some HBL and NHE enterotoxins are known to cause food-borne diseases in humans. Enterotoxin-deficient mutants of member strains of the Bacillus cereus group that do not produce HBL, HBLa1, HBLa2, or NHE enterotoxins are disclosed. Enterotoxin-deficient mutants are suitable for use as biocontrol agents. Methods for making the mutants and for using the mutants are described. |
| FILED | Thursday, July 03, 2014 |
| APPL NO | 14/323647 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) A01N 63/02 (20130101) Peptides C07K 14/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/75 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10017396 | Thomas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| ASSIGNEE(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| INVENTOR(S) | Evan Thomas (Lexington, Kentucky); Kristen Baroudi (Lexington, Kentucky); Yong Bok Go (Lexington, Kentucky); Robert Nordsell (Lexington, Kentucky); Jonathan Melman (Lexington, Kentucky) |
| ABSTRACT | A luminescent composition of matter is characterized by the formula REM2+xEy, where RE may be one or more Rare Earth elements (for example, Eu or Gd), M may be one or more elements selected from the group Al, Ga, B, In, Sc, Lu, and Y; E is one or more elements selected from the group S, Se, O, and Te; x is greater than zero; and y has the value that achieves charge balance in the formula assuming that E has a charge of −2. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591629 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/76 (20130101) C01F 17/0012 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/77 (20130101) C09K 11/7701 (20130101) C09K 11/7728 (20130101) C09K 11/7729 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2021/6417 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/502 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/0803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10020491 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Envia Systems, Inc. (Newark, California) |
| ASSIGNEE(S) | Zenlabs Energy, Inc. (Fremont, California) |
| INVENTOR(S) | Yongbong Han (San Francisco, California); Charan Masarapu (Fremont, California); Haixia Deng (Fremont, California); Yogesh Kumar Anguchamy (Newark, California); Subramanian Venkatachalam (Pleasanton, California); Herman A. Lopez (Sunnyvale, California) |
| ABSTRACT | Silicon based anode active materials are described for use in lithium ion batteries. The silicon based materials are generally composites of nanoscale elemental silicon with stabilizing components that can comprise, for example, silicon oxide-carbon matrix material, inert metal coatings or combinations thereof. High surface area morphology can further contribute to the material stability when cycled in a lithium based battery. In general, the material synthesis involves a significant solution based processing step that can be designed to yield desired material properties as well as providing convenient and scalable processing. |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 13/864212 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) C01B 33/113 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 35/532 (20130101) C04B 35/571 (20130101) C04B 35/806 (20130101) C04B 2235/80 (20130101) C04B 2235/425 (20130101) C04B 2235/428 (20130101) C04B 2235/441 (20130101) C04B 2235/5288 (20130101) C04B 2235/5409 (20130101) C04B 2235/5445 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/362 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/483 (20130101) H01M 4/625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10017789 | Atiyeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
| ASSIGNEE(S) | The Board Of Regents For Oklahoma State University (Stillwater, Oklahoma) |
| INVENTOR(S) | Hasan K. Atiyeh (Stillwater, Oklahoma); John Randall Phillips (Stillwater, Oklahoma); Raymond L. Huhnke (Stillwater, Oklahoma) |
| ABSTRACT | According to an embodiment, there is provided herein a system and method wherein knowledge of the syngas fermentation is combined with standard instrumentation to provide a stable control of gas supply to automatically poise the fermentation to provide both high conversion of CO and H2, and high selectivity for production of ethanol. The control is based on an automatic feedback loop that corrects for operational imbalance and maintains a stable continuous fermentation required for commercial operation. In a further embodiment, feed of syngas to ethanol fermentation can be optimally controlled using the pH of the broth as the input variable for flow control of the gas. This concept will automatically maintain the correct supply of syngas to the fermentation, and provide stable operation at optimal rates. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/080875 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/12 (20130101) C12M 27/02 (20130101) C12M 41/26 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10018298 | Goldish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Gary Goldish (Minneapolis, Minnesota); Andrew Hansen (Minneapolis, Minnesota); Eric Nickel (Minneapolis, Minnesota); John Ferguson (Minneapolis, Minnesota) |
| ABSTRACT | An exercise machine has a mobile base and an upright support extending upwards from the mobile base. An upper support assembly extends forward from an upper portion of the upright support and an exercise device is suspended from the upper support assembly at a location spaced forward from the upright support. The mobile base has caster wheels and can be positioned from either side of a bed so as to extend partially under a bed with the upright support located on one side of the bed and the exercise device suspended over the bed in a position accessible by a patient lying supine in the bed for performing exercise. An anchoring system resists movement of the base for stability when exercise is performed. |
| FILED | Friday, March 06, 2015 |
| APPL NO | 14/640428 |
| ART UNIT | 3764 — AI & Simulation/Modeling |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/005 (20130101) A63B 21/16 (20130101) A63B 21/0058 (20130101) A63B 21/00061 (20130101) A63B 21/00069 (20130101) A63B 21/0083 (20130101) A63B 21/0087 (20130101) A63B 21/225 (20130101) A63B 21/0552 (20130101) A63B 21/0628 (20151001) A63B 22/0002 (20130101) A63B 22/0005 (20151001) A63B 22/0007 (20130101) A63B 22/0046 (20130101) A63B 22/0076 (20130101) A63B 22/0605 (20130101) A63B 22/0694 (20130101) A63B 23/0405 (20130101) A63B 23/1209 (20130101) A63B 23/03525 (20130101) A63B 71/0009 (20130101) A63B 71/023 (20130101) A63B 71/0054 (20130101) A63B 71/0622 (20130101) A63B 2022/0623 (20130101) A63B 2071/025 (20130101) A63B 2208/0252 (20130101) A63B 2210/04 (20130101) A63B 2225/09 (20130101) A63B 2225/093 (20130101) Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 33/0089 (20130101) B60B 33/0092 (20130101) B60B 33/0094 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/18 (20130101) F16M 11/24 (20130101) F16M 11/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Federal Reserve Bank (FED)
| US 10019580 | Bowers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Reserve Bank of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Federal Reserve Bank of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Bradley C. Bowers (Wenonah, New Jersey); Keith Morales (Wynnewood, Pennsylvania); George C. Makin, V (Philadelphia, Pennsylvania); Abraham Vegh (Philadelphia, Pennsylvania) |
| ABSTRACT | A computing device may perform integrity checks on a closed operating system defining a preconfigured user portion and a preconfigured system portion using an integrity checking module. The integrity checking module may access parameters associated with an object stored on the system portion of the operating system. Files on the system portion may be accessed by submitting a query that comprises a file name, a file directory, and at least one parameter to the system portion of the operating system. The integrity checking module may provide an indication of a potential compromise to the integrity of the computing device based on the integrity check. The integrity check may be performed periodically and/or aperiodically. Updated integrity values may be compared against previously determined integrity values to update the integrity check. The integrity checking module may perform the integrity check using a signature function or hashing function to generate the integrity values. |
| FILED | Thursday, November 19, 2015 |
| APPL NO | 14/946241 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10020242 | Katsumata et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Shin Katsumata (Rockford, Illinois); Charles Shepard (DeKalb, Illinois) |
| ABSTRACT | An electronics cooling arrangement includes a housing configured to contain a coolant and an electronic device disposed within the housing. The electronic device has a passageway with at least one inlet and at least one outlet and is configured to allow fluid flowing between the inlet and the outlet to cool the electronic device. |
| FILED | Thursday, April 14, 2016 |
| APPL NO | 15/098810 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/44 (20130101) Original (OR) Class H01L 23/473 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0203 (20130101) H05K 7/20236 (20130101) H05K 7/20327 (20130101) H05K 7/20881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10017396 | Thomas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| ASSIGNEE(S) | EIE MATERIALS, INC. (Lexington, Kentucky) |
| INVENTOR(S) | Evan Thomas (Lexington, Kentucky); Kristen Baroudi (Lexington, Kentucky); Yong Bok Go (Lexington, Kentucky); Robert Nordsell (Lexington, Kentucky); Jonathan Melman (Lexington, Kentucky) |
| ABSTRACT | A luminescent composition of matter is characterized by the formula REM2+xEy, where RE may be one or more Rare Earth elements (for example, Eu or Gd), M may be one or more elements selected from the group Al, Ga, B, In, Sc, Lu, and Y; E is one or more elements selected from the group S, Se, O, and Te; x is greater than zero; and y has the value that achieves charge balance in the formula assuming that E has a charge of −2. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591629 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/76 (20130101) C01F 17/0012 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/77 (20130101) C09K 11/7701 (20130101) C09K 11/7728 (20130101) C09K 11/7729 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2021/6417 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/502 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/0803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10020839 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, LLC (Crownsville, Maryland) |
| ASSIGNEE(S) | RAMPART COMMUNICATIONS, LLC (Crownsville, Maryland) |
| INVENTOR(S) | Matthew Brandon Robinson (Crownsville, Maryland); Andrew Keith Palmisano (Laurel, Maryland); Kregg Elliott Arms (Columbia, Maryland); Audrey Nichole Moore (Stevensville, Maryland) |
| ABSTRACT | Techniques of transmitting wireless communications involve generating orthogonal spreading codes for any number of user devices that are linear combinations of sinusoidal harmonics that match the frequencies within the spread bandwidth. Along these lines, prior to transmitting signals, processing circuitry may generate a set of initial code vectors that form an equiangular tight frame having small cross-correlations. From each of these rows, the processing circuitry produces a new spreading code vector using a code map that is a generalization of a discrete Fourier transform. The difference between the code map and a discrete Fourier transform is that the frequencies of the sinusoidal harmonics are chosen to match the particular frequencies within the spread bandwidth and differ from a center frequency by multiples of the original unspread bandwidth. Different transmitters may then modulate respective signals generated with different spreading code vectors. |
| FILED | Monday, November 14, 2016 |
| APPL NO | 15/351428 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/707 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 10, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180710.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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