FedInvent™ Patents
Patent Details for Tuesday, July 31, 2018
This page was updated on Monday, March 27, 2023 at 05:35 AM GMT
Department of Health and Human Services (HHS)
| US 10034462 | Karin et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michael Karin (La Jolla, California); Atsushi Umemura (Kyoto, Japan); Hayato Nakagawa (Tokyo, Japan) |
| ABSTRACT | The invention provides a non-human animal model for non-alcoholic steatohepatitis (NASH)-induced heptocellular carcinoma, methods of screening for agents for treating heptocellular carcinoma, methods of screening for targets useful in suppressing NASH progression to heptocellular carcinoma, methods of treating heptocellular carcinoma, and compositions for treating the same. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/178935 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2207/25 (20130101) A01K 2227/105 (20130101) A01K 2267/0331 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034646 | Schmidt et al. |
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| FUNDED BY |
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| APPLICANT(S) | Marquette University (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | Marquette University (Milwaukee, Wisconsin) |
| INVENTOR(S) | Tal Gilat Schmidt (Whitefish Bay, Wisconsin); Kevin C. Zimmerman (Milwaukee, Wisconsin) |
| ABSTRACT | A method of processing x-ray images comprises training an artificial neural network to process multi-spectral x-ray projections to determine composition information about an object in terms of equivalent thickness of at least one basis material. The method further comprises providing a multi-spectral x-ray projection of an object, wherein the multi-spectral x-ray projection of the object contains energy content information describing the energy content of the multi-spectral x-ray projection, The multi-spectral x-ray projection is then processed with the artificial neural network to determine composition information about the object, and then the composition information about the object is provided |
| FILED | Friday, September 29, 2017 |
| APPL NO | 15/721146 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/50 (20130101) A61B 6/482 (20130101) A61B 6/583 (20130101) A61B 6/5205 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6262 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) G06T 2211/408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034839 | Panitch et al. |
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| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Alyssa Panitch (West Lafayette, Indiana); Brandon Seal (Pleasant Grove, Utah); Jamie L. Brugnano (Lafayette, Indiana); Rush L. Bartlett (West Lafayette, Indiana); Shaili Sharma (Lafayette, Indiana); James McMasters (West Lafayette, Indiana) |
| ABSTRACT | The invention relates to compositions and methods for the treatment of inflammatory disease states. In particular, the invention relates to the use of a nanoparticle incorporated kinase inhibiting peptide to treat inflammatory disease states. |
| FILED | Wednesday, August 10, 2016 |
| APPL NO | 15/233598 |
| ART UNIT | 1675 — Optics |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5146 (20130101) Original (OR) Class A61K 38/005 (20130101) A61K 38/08 (20130101) A61K 38/16 (20130101) A61K 38/17 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034845 | Chandraratna et al. |
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| FUNDED BY |
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| APPLICANT(S) | IO Therapeutics, Inc. (Laguna Hills, California); Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | lo Therapeutics, Inc. (Santa Ana, California) |
| INVENTOR(S) | Roshantha A. Chandraratna (Laguna Hills, California); Ethan Dmitrovsky (Hanover, New Hampshire); Elizabeth Nowak (West Lebanon, New Hampshire); Randolph Noelle (Plainfield, New Hampshire) |
| ABSTRACT | The present specification provides RXR agonist compounds, compositions comprising such RXR agonists, and methods using such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection as well as use of such RXR agonists to manufacture a medicament and use of such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection. |
| FILED | Thursday, February 19, 2015 |
| APPL NO | 14/626339 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0073 (20130101) A61K 31/47 (20130101) A61K 31/192 (20130101) Original (OR) Class A61K 31/201 (20130101) A61K 31/216 (20130101) A61K 31/343 (20130101) A61K 31/353 (20130101) A61K 31/4704 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034913 | Chadha et al. |
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| FUNDED BY |
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| APPLICANT(S) | Health Research, Inc. (Buffalo, New York) |
| ASSIGNEE(S) | Health Research, Inc. (Buffalo, New York) |
| INVENTOR(S) | Kailash C. Chadha (Williamsville, New York); Gary J. Smith (Buffalo, New York) |
| ABSTRACT | Provided are peptide sequences derived from prostate serum antigen (PSA). The peptides are provided in cyclic and linear form. Methods for using the peptides for inhibition of angiogenesis, such as angiogenesis in a tumor, are provided. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 14/817648 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/12 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034917 | Fahmy |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut) |
| ABSTRACT | Compositions for delivery of growth factors needed for stable Tregs and methods of use thereof are provided. In preferred embodiments, the compositions can induce, increase, or enhance a functionally robust induced CD4 Treg population (e.g., Foxp3+ Treg) in vivo or ex vivo. The compositions generally include delivery vehicles including TGF-β and IL-2. Delivery vehicles include, for example, polymeric particles, silica particles, liposomes, or multilamellar vesicles. The TGF-β and IL-2 are typically co-loaded into, attached to the surface of, and/or enclosed within the delivery vehicle into the same particle for simultaneous co-delivery to cells such as T cells. Preferably the delivery vehicles are targeted to CD4. The compositions and cells treated therewith can be used in various methods of treating, for example, inflammation, inflammatory and autoimmune diseases and disorders, and inducing or maintaining tolerance including graft and transplant tolerance. |
| FILED | Sunday, May 15, 2016 |
| APPL NO | 15/155055 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1271 (20130101) A61K 9/1277 (20130101) A61K 9/5153 (20130101) A61K 38/1841 (20130101) Original (OR) Class A61K 38/2013 (20130101) A61K 47/6849 (20170801) A61K 47/6937 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034924 | Powell et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Jonathan Powell (Baltimore, Maryland); Ying-Chun Lo (Baltimore, Maryland); Michael Edidin (Baltimore, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides methods and compositions for activation of clustered receptors on a target cell using nanocarrier-associated ligands, particularly methods and compositions for targeted activation of clustered receptors on antigen-experienced T cells using nanocarrier-associated antibodies. |
| FILED | Monday, December 22, 2014 |
| APPL NO | 15/106400 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 47/6849 (20170801) A61K 47/6929 (20170801) A61K 47/48561 (20130101) A61K 47/48884 (20130101) A61K 2039/55516 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 2501/515 (20130101) C12N 2501/599 (20130101) C12N 2531/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034927 | Pier et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gerald B. Pier (Brookline, Massachusetts); Nikolay Nifantiev (Moscow, Russian Federation); Yury Tsvetkov (Moscow, Russian Federation); Marina Gening (Moscow, Russian Federation) |
| ABSTRACT | The invention relates to the compositions of synthetic oligo-β-(1→6)-2-amino-2-deoxy-D-glu-copyranosides conjugated to carriers, and methods for making and use same. |
| FILED | Wednesday, September 07, 2016 |
| APPL NO | 15/258417 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/085 (20130101) Original (OR) Class A61K 47/646 (20170801) A61K 47/6415 (20170801) A61K 2039/55 (20130101) A61K 2039/552 (20130101) A61K 2039/575 (20130101) A61K 2039/6037 (20130101) Acyclic or Carbocyclic Compounds C07C 327/32 (20130101) Heterocyclic Compounds C07D 207/46 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/06 (20130101) Peptides C07K 16/1232 (20130101) C07K 16/1271 (20130101) C07K 2317/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034929 | Ding et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shou-Wei Ding (Riverside, California); Yang Li (Shanghai, China PRC) |
| ABSTRACT | The disclosure provides recombinant viral vectors and attenuated viruses and viral vaccines comprising a virus lacking a functional viral RNA suppressor of host RNAi. |
| FILED | Monday, March 17, 2014 |
| APPL NO | 14/775938 |
| ART UNIT | 1674 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/1131 (20130101) C12N 2310/14 (20130101) C12N 2760/14122 (20130101) C12N 2760/14162 (20130101) C12N 2770/30022 (20130101) C12N 2770/30034 (20130101) C12N 2770/30062 (20130101) C12N 2770/32222 (20130101) C12N 2770/32262 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034935 | Davido et al. |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas); Saint Louis Univeristy (St. Louis, Missouri) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas); Saint Louis University (St. Louis, Missouri) |
| INVENTOR(S) | David J. Davido (Lawrence, Kansas); Lynda Anne Morrison (Webster Groves, Missouri) |
| ABSTRACT | A mutant HSV-1 (referred to herein as KOS-NA) was generated. KOS-NA contains novel mutations in the UL39 gene, which encodes for a protein that is a large subunit of ribonucleotide reductase (i.e., ICP6). These UL39 mutations were found to alter two amino acids in ICP6 (R950H and L393P) and are responsible for attenuation of KOS-NA in vivo, and resulted in diminished ICP6 protein levels. These novel UL39 mutations regulate the expression and/or stability of ICP6 and severely impact HSV-1 pathogenesis. Mutant HSV viruses containing these mutations appear to protect against HSV infection and can serve as therapeutic vaccines to help combat preexisting HSV infection in infected individuals. |
| FILED | Wednesday, April 05, 2017 |
| APPL NO | 15/480147 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) A61K 35/763 (20130101) A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 39/245 (20130101) A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) C07K 14/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16632 (20130101) C12N 2710/16634 (20130101) C12N 2710/16643 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034936 | Stapleton et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | The University of Iowa Research Foundation (Iowa, Iowa); The United States of America as represented by the Secretary of the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jack T. Stapleton (Iowa City, Iowa); Jinhua Xiang (Iowa City, Iowa); Donna Klinzman (Coralville, Iowa); James H. McLinden (Coralville, Iowa) |
| ABSTRACT | GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods involving an anti-GBV-C antibody or other GBV-C binding agent, or a GBV-C antigen, for inhibiting and treating HIV infections. |
| FILED | Friday, August 15, 2014 |
| APPL NO | 14/460517 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/29 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 14/05 (20130101) C07K 14/1841 (20130101) C07K 16/109 (20130101) C07K 2317/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24222 (20130101) C12N 2770/24234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034945 | Kaplan et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Fiorenzo Omenetto (Lexington, Massachusetts); Gary G. Leisk (Wilmington, Massachusetts); Tim Jia-Ching Lo (Taoyuan, Taiwan); Benjamin Partlow (Marlborough, Massachusetts); Rosario Friedman (Conway, Massachusetts) |
| ABSTRACT | The present disclosure relates generally to compositions and methods for production of three-dimensional constructs with high mechanical strength and/or stiffness. |
| FILED | Monday, July 15, 2013 |
| APPL NO | 14/414245 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Characteristic Features of Footwear; Parts of Footwear A43B 1/02 (20130101) A43B 1/06 (20130101) A43B 13/02 (20130101) A43B 23/0205 (20130101) A43B 23/0225 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 47/42 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/50 (20130101) A61L 27/3604 (20130101) A61L 31/047 (20130101) Presses in General B30B 9/28 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034960 | Fisher et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Children's National Medical Center (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | John Patrick Fisher (Kensington, Maryland); Anthony Melchiorri (Ellicott City, Maryland); Narutoshi Hibino (Columbus, Ohio); Axel Krieger (Alexandria, Virginia); John P. Costello (Washington, District of Columbia); Carolyn Cochenour (Washington, District of Columbia) |
| ABSTRACT | A composition including PPF or a PPF copolymer that can be used to fabricate biodegradable structures. The composition can be used in 3-D patterning (e.g., 3-D printing and sterolighography) methods. For example, 3-D patternable compositions include PPF or a PPF copolymer, a photoinitiator or photoinitiators, and a resolution control inhibitor or inhibitors. The compositions can be used to make biodegradable structures (such as cardivascular scaffolds). The biodegradable structures can be surface functionalized. The biodegradable structures can be used in methods of blood delivery in an individual. |
| FILED | Friday, June 06, 2014 |
| APPL NO | 14/895617 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) Original (OR) Class A61L 27/22 (20130101) A61L 27/26 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/507 (20130101) A61L 2300/252 (20130101) A61L 2300/256 (20130101) A61L 2300/414 (20130101) A61L 2430/20 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 267/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/918 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/04 (20130101) C08K 5/092 (20130101) C08K 5/132 (20130101) C08K 5/5397 (20130101) Compositions of Macromolecular Compounds C08L 67/06 (20130101) C08L 67/06 (20130101) C08L 67/06 (20130101) C08L 67/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035009 | Sommer et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Frank Graham Sommer (Stanford, California); Chris J. Diederich (Novato, California) |
| ABSTRACT | A method of treating pancreatic cancer includes: inserting a device into a stomach or a duodenum; securing at least a portion of the device in position relative to the stomach or the duodenum; and delivering ultrasonic energy from the device to treat a target site in a pancreas. |
| FILED | Tuesday, April 15, 2014 |
| APPL NO | 14/253801 |
| ART UNIT | 3777 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2018/0022 (20130101) A61B 2018/00267 (20130101) A61B 2018/00285 (20130101) A61B 2018/00482 (20130101) A61B 2090/374 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0092 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/022 (20130101) A61N 2007/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035769 | Stoltz et al. |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Brian M. Stoltz (San Marino, California); Scott C. Virgil (Pasadena, California); David E. White (Wayne, Pennsylvania); Taiga Yurino (Kyoto, Japan); Yiyang Liu (Pasadena, California); Douglas C. Behenna (Laguna Niguel, California); Douglas Duquette (Los Angeles, California); Christian Eidamshaus (Pasadena, California) |
| ABSTRACT | The invention provides heterocyclic compounds with quaternary centers and methods of preparing compounds. Methods include the method for the preparation of a compound of Formula (II): comprising treating a compound of Formula (I): with a transition metal catalyst and under alkylation conditions as valence and stability permit. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/366590 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 207/27 (20130101) C07D 207/277 (20130101) C07D 211/76 (20130101) C07D 211/78 (20130101) Original (OR) Class C07D 211/90 (20130101) C07D 211/96 (20130101) C07D 223/10 (20130101) C07D 265/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035806 | Yen et al. |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Melanie A. Yen (Pasadena, California); Harry B. Gray (Pasadena, California); Robert H. Grubbs (South Pasadena, California); Joshua Palmer (Pasadena, California) |
| ABSTRACT | The present invention is directed to derivatized corroles, methods of making and using the same as imaging and therapeutic agents. In certain embodiments, the corroles are compounds having a Structure (I-H) and (I-M): where R1, R2, R3, and R4 are independently —F or —N(H)—(CH2)m—Y, provided that at least one of R1, R2, R3, and R4 is —N(H)—(CH2)m—Y, and m and Y are described herein. |
| FILED | Thursday, October 06, 2016 |
| APPL NO | 15/286983 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/22 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035819 | Evans et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Ronald M. Evans (La Jolla, California); Michael Downes (La Jolla, California) |
| ABSTRACT | Provided herein are deuterated compounds and compositions useful in increasing PPARδ activity. The compounds have a formula where L5 comprises at least one deuterium. Exemplary species include The compounds and compositions provided herein are useful for the treatment of PPARδ related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases). |
| FILED | Friday, April 07, 2017 |
| APPL NO | 15/482385 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/75 (20130101) Heterocyclic Compounds C07D 213/40 (20130101) C07D 213/56 (20130101) C07D 231/12 (20130101) C07D 295/13 (20130101) C07D 307/54 (20130101) C07D 333/38 (20130101) C07D 401/12 (20130101) C07D 405/12 (20130101) C07D 409/12 (20130101) Peptides C07K 5/06026 (20130101) C07K 5/06034 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035823 | Franco |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Alessandra Franco (San Diego, California) |
| ABSTRACT | Provided are compositions, including isolated, synthetic or recombinant peptides for: expanding regulatory T cells (Treg) populations; for treating or ameliorating a vascular inflammation, and Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries, including vascular coronary abnormalities, and acute or chronic vascular inflammatory abnormalities, and methods for making and using them. Provided are immunotherapies for promoting expansion of natural, Treg to establish, or re-establish, vascular homeostasis; or, for ameliorating: a disease or condition associated with an autoimmune disease or condition; an immune-mediated vascular disorder; a disease or condition treated with intravenous immunoglobulin (IVIG) therapy; a vascular coronary abnormality; an acute or a chronic vasculitis; an autoimmune inflammatory vasculitis; a T cell mediated pediatric vasculitis; Kawasaki disease (KD) or a pediatric acute vasculitis of the coronary arteries; atherosclerosis; preventing miscarriage in autoimmune women; rheumatoid arthritis or Juvenile Idiopathic Arthritis; a neoplastic hematological disorder, or a leukemia. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 15/510667 |
| ART UNIT | 1676 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/127 (20130101) A61K 38/00 (20130101) A61K 39/0005 (20130101) A61K 2039/545 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035825 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Guangping Gao (Westborough, Massachusetts); Terence Flotte (Holden, Massachusetts); Jun Xie (Shrewsbury, Massachusetts) |
| ABSTRACT | The invention in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the invention relates to gene transfer methods using the recombinant adeno-associate viruses. In some aspects, the invention relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same. |
| FILED | Wednesday, January 27, 2016 |
| APPL NO | 15/007559 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 35/76 (20130101) A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035832 | Schlom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Schlom (Potomac, Maryland); Kwong-Yok Tsang (Bethesda, Maryland) |
| ABSTRACT | The invention provides a human cytotoxic T lymphocyte (CTL) agonist epitope from the C-terminal subunit of mucin 1 (MUC1-C), which can be used as a peptide, polypeptide (protein), and/or in vaccine or other composition for the prevention or therapy of cancer. The invention further provides a nucleic acid encoding the peptide, protein, or polypeptide, a vector comprising the nucleic acid, a cell comprising the peptide, polypeptide, nucleic acid, or vector, and compositions thereof. |
| FILED | Wednesday, October 22, 2014 |
| APPL NO | 15/031435 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/00 (20130101) A61K 38/00 (20130101) A61K 38/20 (20130101) A61K 38/20 (20130101) A61K 38/22 (20130101) A61K 38/22 (20130101) A61K 38/191 (20130101) A61K 38/191 (20130101) A61K 38/193 (20130101) A61K 38/193 (20130101) A61K 38/195 (20130101) A61K 38/195 (20130101) A61K 38/217 (20130101) A61K 38/217 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/5154 (20130101) A61K 2039/55588 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/82 (20130101) C07K 14/4727 (20130101) Original (OR) Class C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/24143 (20130101) C12N 2710/24171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035833 | Bottaro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Donald P. Bottaro (Rockville, Maryland); Fabiola Cecchi (Rockville, Maryland) |
| ABSTRACT | The present invention provides variant VEGF polypeptides which have been altered in their C-terminal heparin binding region to lower their heparin binding affinity. These variants have been found to act as receptor antagonists for VEGF receptors and antagonize angiogenesis. These variants are useful to treat diseases characterized by pathological angiogenesis. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 15/411112 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1866 (20130101) Peptides C07K 14/52 (20130101) C07K 14/71 (20130101) C07K 14/475 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035834 | Prockop et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Darwin J. Prockop (Philadelphia, Pennsylvania); RyangHwa Lee (Round, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Darwin J. Prockop (Philadelphia, Pennsylvania); RyangHwa Lee (Round, Texas) |
| ABSTRACT | The present invention provides compositions comprising mesenchymal stem cells (MSCs), and methods for their novel use in the repair of cardiac damage and treatment of inflammatory diseases. The invention also provides methods for using TSG-6 protein that is secreted by MSCs under certain conditions, for repair of cardiac damage and inflammatory disease. The compositions of the invention may be particularly useful in restoring cardiac function following cardiac damage, including, but not limited to, myocardial infarction, as well as in reducing symptoms of inflammatory disease. |
| FILED | Thursday, June 18, 2009 |
| APPL NO | 12/487373 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/525 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 2501/25 (20130101) C12N 2501/585 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035844 | Kwong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Peter D. Kwong (Washington, District of Columbia); Gary J. Nabel (Cambridge, Massachusetts); Rebecca S. Rudicell (Silver Spring, Maryland); John Mascola (Rockville, Maryland); Mark Connors (Bethesda, Maryland); Ivelin Georgiev (Nashville, Tennessee); Jiang Zhu (Ashburn, Virginia); Young Do Kwon (Rockville, Maryland); Tongqing Zhou (Boyds, Maryland); Yongping Yang (Potomac, Maryland); Baoshan Zhang (Bethesda, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Xueling Wu (Potomac, Maryland); Zhi-yong Yang (Potomac, Maryland); Wei Shi (Rockville, Maryland) |
| ABSTRACT | Monoclonal neutralizing antibodies that specifically bind to HIV-1 gp120 and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV infection is disclosed. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 15/612846 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/41 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 33/56988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035845 | Mascola et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); University of Washington (Seattle, Washington) |
| INVENTOR(S) | John Mascola (Rockville, Maryland); Richard Wyatt (San Diego, California); Xueling Wu (Potomac, Maryland); Yuxing Li (Boyds, Maryland); Carl-Magnus Hogerkorp (Vellinge, Sweden); Mario Roederer (Washington, District of Columbia); Zhi-yong Yang (Potomac, Maryland); Gary Nabel (Cambridge, Massachusetts); Peter Kwong (Washington, District of Columbia); Tongqing Zhou (Boyds, Maryland); Mark Connors (Bethesda, Maryland); William Schief (Encinitas, California) |
| ABSTRACT | Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and the use of these antibodies are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes. |
| FILED | Thursday, July 27, 2017 |
| APPL NO | 15/661867 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/10011 (20130101) C12N 2740/16011 (20130101) C12N 2740/16111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035846 | Maynard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); Synthetic Biologics, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); SYNTHETIC BIOLOGICS, INC. (Rockville, Maryland) |
| INVENTOR(S) | Jennifer Maynard (Austin, Texas); Annalee Nguyen (Austin, Texas); Eduardo Padlan (Rockville, Maryland); Ellen Wagner (Larkspur, Colorado) |
| ABSTRACT | The present invention relates to humanized antibodies which bind the pertussis toxin protein and their use as therapeutic agents. In particular, the present invention is directed to improved humanized 1B7 and 11E6 antibodies which bind the pertussis toxin protein. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/356217 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/40 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/1225 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035848 | Wiestner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Adrian U. Wiestner (Bethesda, Maryland); Martin W. Skarzynski (North Bethesda, Maryland); Margaret A. Lindorfer (Keswick, Virginia); Ronald P. Taylor (Keswick, Virginia); Christoph Rader (Jupiter, Florida); Berengere Vire (Le Cres, France) |
| ABSTRACT | An anti-C3d antibody or antibody fragment; method for use thereof to kill cancer cells; and related methods and compositions. |
| FILED | Thursday, January 08, 2015 |
| APPL NO | 15/110577 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/11 (20130101) Peptides C07K 14/472 (20130101) C07K 14/7051 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 16/3061 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/515 (20130101) C07K 2317/565 (20130101) C07K 2317/732 (20130101) C07K 2317/734 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035857 | Noelle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Randolph J. Noelle (Plainfield, New Hampshire); Li Wang (Norwich, Vermont) |
| ABSTRACT | The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates αCD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon αCD3/αGITR stimulation. This protein has been designated Treg-sTNF. Proteins, antibodies, activated T cells and methods for using the same are disclosed. In particular methods of using these proteins and compounds, preferably antibodies, which bind or modulate (agonize or antagonize) the activity of these proteins, as immune modulators and for the treatment of cancer, autoimmune disease, allergy, infection and inflammatory conditions, e.g. multiple sclerosis is disclosed. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 14/940940 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/70596 (20130101) C07K 16/2827 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035858 | Blumberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Richard S. Blumberg (Waltham, Massachusetts); Kristi Baker (Brookline, Massachusetts); Timo Rath (Cambridge, Massachusetts) |
| ABSTRACT | Described herein are compositions for increasing IL-12 production comprising IgG or a fragment thereof or a variant thereof and uses of said compositions for treating cancer and infectious diseases. Also described herein are compositions for decreasing IL-12 production comprising an agent that inhibits signaling mediated by interaction between FcRn and IgG and uses of said compositions for treating autoimmune diseases. Further described herein are methods for assessing efficacy of treatment by monitoring levels of various cytokines in the subject. |
| FILED | Tuesday, November 25, 2014 |
| APPL NO | 15/039524 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/00 (20130101) C07K 16/244 (20130101) C07K 16/283 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/574 (20130101) G01N 33/6854 (20130101) G01N 33/6863 (20130101) G01N 33/6866 (20130101) G01N 33/6869 (20130101) G01N 2333/57 (20130101) G01N 2333/525 (20130101) G01N 2333/5434 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035871 | Langer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert S. Langer (Newton, Massachusetts); Jeffrey M. Karp (Brookline, Massachusetts); Maria Jose Maio Nunes-Pereira (Cambridge, Massachusetts); Ben Ouyang (Bedford, Massachusetts); Lino Da Silva Ferreira (Coimbra, Portugal); Debanjan Sarkar (Williamsville, New York) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Biocant-Center of Innovation and Biotechnology (Cantanhede, Portugal) |
| INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Jeffrey M. Karp (Brookline, Massachusetts); Maria Jose Maio Nunes-Pereira (Cambridge, Massachusetts); Ben Ouyang (Bedford, Massachusetts); Lino Da Silva Ferreira (Coimbra, Portugal); Debanjan Sarkar (Williamsville, New York) |
| ABSTRACT | Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B—)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink. |
| FILED | Sunday, August 26, 2012 |
| APPL NO | 13/594834 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/14 (20130101) C08G 18/4236 (20130101) Original (OR) Class C08G 18/4238 (20130101) C08G 18/4283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035984 | Palese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York); Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Dmitriy Zamarin (New York, New York); Yuman Fong (New York, New York) |
| ABSTRACT | Described herein are chimeric Newcastle disease viruses engineered to express a heterologous interferon antagonist and compositions comprising such viruses. The chimeric Newcastle disease viruses and compositions are useful in the treatment of cancer. |
| FILED | Monday, November 16, 2015 |
| APPL NO | 14/942400 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/13 (20130101) A61K 39/0011 (20130101) A61K 39/17 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/16122 (20130101) C12N 2760/18121 (20130101) C12N 2760/18122 (20130101) C12N 2760/18132 (20130101) C12N 2760/18143 (20130101) C12N 2760/18171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036008 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jinpeng Wang (Goleta, California); Hyongsok Soh (Santa Barbara, California); Qiang Gong (Goleta, California) |
| ABSTRACT | The present disclosure provides a method for identifying one or more nucleic acid agents, e.g., aptamers, having a desired property from a mixture of candidate nucleic acid agents. The method generally includes immobilizing the mixture of candidate nucleic acid agents onto particles, wherein only a subset of the candidate nucleic acid agents are immobilized on any one of the particles, and wherein the subset is present in multiple copies. The particles are exposed to a target, and particles including candidate nucleic acid agents having the desired property are isolated. In this way, one or more nucleic acid agents having the desired property may be identified. Related compositions and nucleic acid agents identified as having one or more desired properties are also provided. |
| FILED | Thursday, November 21, 2013 |
| APPL NO | 14/647775 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1037 (20130101) C12N 15/1048 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/351 (20130101) C12N 2320/11 (20130101) C12N 2320/13 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 2541/101 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036009 | Medina-Kauwe |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Lali K. Medina-Kauwe (Porter Ranch, California) |
| ABSTRACT | The invention relates to methods for isolating traffic-enhancing mutants of drug delivery proteins. In one embodiment, the invention provides a carrier for delivering a therapeutic agent to an organelle, comprising a polypeptide encoded by a mutant penton base gene. In another embodiment, the invention provides a method of enhancing trafficking to a cell by administering a composition comprising a penton base (PB) protein with one or more mutations that enhance cellular entry. |
| FILED | Friday, August 02, 2013 |
| APPL NO | 14/419233 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/645 (20170801) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/1037 (20130101) C12N 15/1058 (20130101) Original (OR) Class C12N 2710/10322 (20130101) C12N 2710/10341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036015 | Kathju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandeep Kathju (Coraopolis, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sandeep Kathju (Coraopolis, Pennsylvania); Latha Satish (Wexford, Pennsylvania) |
| ABSTRACT | Embodiments of the present disclosure are directed to methods of treating, reducing or preventing fibrosis or scarring including administering a therapeutic molecular agent selected from the group consisting of an agent that inhibits chaperonin containing T-complex polypeptide subunit eta polypeptide (“CCT-eta”), an agent that inhibits α-Smooth Muscle Actin (“α-SMA”), or a combination thereof. In embodiments, the fibrosis may include Dupuytren's contracture, Peyronie's disease, pulmonary fibrosis, cirrhosis, interstitial lung disease or scarring alopecia. |
| FILED | Monday, January 05, 2015 |
| APPL NO | 14/589470 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036018 | Croce et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carlo M. Croce (Columbus, Ohio); Denis C. Guttridge (Upper Arlington, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carlo M. Croce (Columbus, Ohio); Denis C. Guttridge (Upper Arlington, Ohio) |
| ABSTRACT | The present invention relates, in various embodiments, to methods of treating cachexia (e.g., cancer cachexia) in a patient. The methods comprise administering at least one compound for inhibiting, in alternative embodiments, the expression or activity of a microRNA that is present in microvesicles secreted from cancer cells in the patient (e.g., a miR-21 gene product), the expression or activity of a Toll-like receptor (e.g., TLR7, TLR8), the expression or activity of a c-Jun N-terminal kinase (JNK), the secretion of microvesicles from cancer cells, or the fusion of microvesicles from cancer cells with muscle cells or adipocytes. The present invention also relates, in certain embodiments, to pharmaceutical compositions comprising at least two compounds useful in the practice of the methods of the invention described herein. |
| FILED | Tuesday, March 10, 2015 |
| APPL NO | 15/124425 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036020 | Jaeger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Laura B. Jaeger (North Bethesda, Maryland); Avindra Nath (Ellicott City, Maryland); Eugene Major (Darnestown, Maryland); Maria Chiara Kushner-Monaco (Kensington, Maryland); Michael W. Ferenczy (Washington, District of Columbia) |
| ABSTRACT | The instant invention provides compositions and methods for inhibiting the JC Virus (JCV), and that can be used, for example, for treating progressive multifocal leukoencephalopathy (PML). Antisense oligonucleotides are provided which are effective in inhibiting JCV replication or multiplication, alone or in a combination. In preferred embodiments, the oligonucleotides contain modifications. |
| FILED | Friday, September 19, 2014 |
| APPL NO | 15/023352 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/084 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1131 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/346 (20130101) C12N 2310/3521 (20130101) C12N 2710/22011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036039 | Trobridge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Grant D. Trobridge (Lake Forest Park, Washington); Hans-Peter Kiem (Seattle, Washington) |
| ABSTRACT | Provided herein are Cocal vesiculovirus envelope pseudotyped retroviral vectors that exhibit high titers, broad species and cell-type tropism, and improved serum stability. Disclosed Cocal vesiculovirus envelope pseudotyped retroviral vectors may be suitably employed for gene therapy applications and, in particular, for the ex vivo and in vivo delivery of a gene of interest to a wide variety of target cells. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 15/684837 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 48/00 (20130101) A61K 2035/124 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2740/16043 (20130101) C12N 2740/16045 (20130101) C12N 2760/20222 (20130101) C12N 2760/20243 (20130101) C12N 2810/6081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036042 | Wurtzel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Eleanore T. Wurtzel (Riverdale, New York); Jesús Beltrán (New York, New York) |
| ABSTRACT | A method for isomerizing a double bond is provided. A substrate is exposed to an isomerase enzyme, wherein the isomerase enzyme comprises a redox-regulated ligand switch and heme b cofactor. A reducing agent is added which changes iron (III) to iron (II). The enzyme isomerizes double bonds in the iron (II) state but not in the iron (III) state. In one embodiment, the enzyme is homologous with 15-cis-ζ-carotene isomerase (Z-ISO). |
| FILED | Wednesday, June 01, 2016 |
| APPL NO | 15/169894 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/90 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) C12P 5/026 (20130101) Original (OR) Class C12P 23/00 (20130101) Enzymes C12Y 502/01012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036055 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kun Zhang (Brighton, Massachusetts); Joseph Chou (Jamaica Plain, Massachusetts) |
| ABSTRACT | Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided. |
| FILED | Thursday, May 22, 2014 |
| APPL NO | 14/284764 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2535/113 (20130101) C12Q 2535/113 (20130101) C12Q 2535/113 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036059 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David Yu Zhang (Houston, Texas); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof. |
| FILED | Tuesday, November 25, 2014 |
| APPL NO | 14/553165 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036068 | Boutaud et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Olivier Boutaud (Nashville, Tennessee); Elias Haddad (Nashville, Tennessee) |
| ABSTRACT | Methods are provided for diagnosis, prognosis, and treatment associated with a cardiovascular event in a subject as well as methods of providing anti-platelet therapy. The methods can comprise obtaining a sample from the subject, and determining the presence of at least two single nucleotide polymorphisms (SNP) in the sample selected from Rs7541936 in PTGER3, Rs977214 in PTGER3, and Rs2206343 in PTGER3. The methods can also comprise determining the presence in the sample of Rs4383756 in PTGER4. Some methods comprise administering conventional anti-platelet therapy to the subject if Rs4383756 in PTGER4 is present in the sample. Furthermore, some methods comprise administering an EP3 antagonist and/or conventional anti-platelet therapy to the subject if Rs4383756 in PTGER4 is not present in the sample. The cardiovascular event can involve thrombosis or an embolic event, a myocardial infarction, a stroke, a primary cardiovascular event, or coronary artery disease. |
| FILED | Monday, July 08, 2013 |
| APPL NO | 13/937011 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4045 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036069 | Noth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois); University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); THE UNIVERSITY OF CHICAGO (Chicago, Illinois); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Imre Noth (Chicago, Illinois); Yong Huang (Dyer, Indiana); Jose David Herazo-Maya (North Haven, Connecticut); Naftali Kaminski (New Haven, Connecticut); Kevin Gibson (Gibsonia, Pennsylvania); Joe G. N. Garcia (Tucson, Arizona) |
| ABSTRACT | Disclosed are methods are kits for evaluating predicting whether an individual IPF has slowly or rapidly progressive IPF. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 14/358945 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036076 | Lindstrom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Dept. of Health and Human Servic (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services, Center for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Stephen Lindstrom (Atlanta, Georgia); Lamorris Loftin (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/182852 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class C12Q 1/6837 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036248 | Defibaugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joy MM Delaware, Inc. (Wilmington, Delaware); The United States of America, as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Joy Global Underground Mining LLC (Warrendale, Pennsylvania); The United States of America, as represented by the Secretary of the Dep. of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Joseph Defibaugh (Franklin, Pennsylvania); Hugo Camargo (South Park, Pennsylvania); Junyi Yang (Cupertino, California) |
| ABSTRACT | A cutter head for a mining machine includes a first end and a second end with a drum axis extending between the first and the second ends. The cutter head also includes a web coupled to the second end of the drum. The web includes a plurality of arcuate apertures. Each arcuate aperture extends through an angle about the drum axis. The cutter head further includes a plurality of first ribs coupled to the web. Each of the first ribs is positioned between adjacent arcuate apertures. The cutter head also includes a plurality of second ribs coupled to the web. Each of the second ribs extend across one of the plurality of arcuate apertures. A first angle that extends between one of the first ribs and an adjacent one of the second ribs is different than a second angle extending between the one first rib and another adjacent second rib. |
| FILED | Friday, October 09, 2015 |
| APPL NO | 14/880052 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Mining or Quarrying E21C 25/10 (20130101) Original (OR) Class E21C 35/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036743 | Giese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | Roger Giese (Hanover, Massachusetts); Poguang Wang (Westborough, Massachusetts) |
| INVENTOR(S) | Roger Giese (Hanover, Massachusetts); Poguang Wang (Westborough, Massachusetts) |
| ABSTRACT | The invention provides methods of detecting an analyte by multi-stage mass spectrometry with improved S/N ratio. An analyte is labeled with a positively-charged mass tag to form a precursor ion that leads by anchimeric assistance to a greatly enhanced, analyte-characteristic first product ion that can, in turn, lead to a greatly enhanced, analyte-characteristic second product ion in a mass spectrometer. Either a three stage mass spectrometer (true MS3) or a two-stage mass spectrometer (MS2) operated in a pseudo MS3 mode can be used. The precursor ion is split via an anchimeric-assisted reaction to form a first product ion, which in turn can be fragmented to form the second product ion. The methods offer extreme ultrasensitivity, at the low amol level. The invention also provides anchimeric mass tags for use in the methods. A wide variety of previously undetectable analytes of biological or environmental origin can be detected and quantified. |
| FILED | Monday, February 01, 2016 |
| APPL NO | 15/547588 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 217/48 (20130101) C07C 217/58 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) Original (OR) Class G01N 2458/15 (20130101) G01N 2560/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036758 | Deisseroth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Karl Deisseroth (Palo Alto, California); Edward S. Boyden (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Karl Deisseroth (Palo Alto, California); Edward S. Boyden (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides compositions and methods for light-activated cation channel proteins and their uses within cell membranes and subcellular regions. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-activated cation channels to specific cells or defined cell populations. In particular the invention provides millisecond-timescale temporal control of cation channels using moderate light intensities in cells, cell lines, transgenic animals, and humans. The invention provides for optically generating electrical spikes in nerve cells and other excitable cells useful for driving neuronal networks, drug screening, and therapy. |
| FILED | Monday, March 01, 2010 |
| APPL NO | 12/715259 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/05 (20130101) A01K 2227/40 (20130101) A01K 2227/105 (20130101) A01K 2227/703 (20130101) A01K 2227/706 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/18 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/353 (20130101) A61K 31/405 (20130101) A61K 31/4172 (20130101) A61K 35/30 (20130101) A61K 35/30 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3604 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0601 (20130101) A61N 5/0622 (20130101) Peptides C07K 14/405 (20130101) C07K 14/705 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/15043 (20130101) C12N 2740/15071 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) Original (OR) Class G01N 2500/04 (20130101) G01N 2500/10 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 530/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036796 | Reeder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Scott Brian Reeder (Middleton, Wisconsin); Diego Hernando (Madison, Wisconsin); Samir Sharma (Madison, Wisconsin) |
| ABSTRACT | Phantoms for use in magnetic resonance imaging (“MRI”) and, in particular, for use in quantifying fat concentration, iron concentration, or both, are provided. The phantoms are constructed to accurately reflect in vivo magnetic resonance signal behavior in the presence of both fat and iron. The phantoms described here can thus be used for phantom-based validation of MRI techniques for the joint quantification of fat and iron concentration, for phantom-based validation of MRI techniques for quantifying fat concentration in the presence of iron overload, and for phantom-based validation of MRI techniques for quantifying iron concentration given the confounding presence of fat. |
| FILED | Monday, June 15, 2015 |
| APPL NO | 14/739571 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) Original (OR) Class G01R 33/4828 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037285 | Ramachandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Umakishore Ramachandran (Lilburn, Georgia); Mungyung Ryu (Atlanta, Georgia) |
| ABSTRACT | The disclosed technology includes techniques for efficiently streaming media content from a multi-tiered storage system. An example implementation may be used for adaptive HTTP streaming of video segments and other content. In some implementations, flash memory SSDs (SLC or MLC) may form an intermediate cache layer between a first layer of DRAM cache and third layer of HDDs. Significant architectural elements of various implementations include optimal write granularity to overcome the write amplification effect of flash memory SSDs and a QoS-sensitive caching strategy that monitors the activity of the flash memory SSDs to ensure that video streaming performance is not hampered by the caching activity. |
| FILED | Wednesday, January 14, 2015 |
| APPL NO | 14/597193 |
| ART UNIT | 2131 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 3/064 (20130101) G06F 3/0611 (20130101) G06F 3/0629 (20130101) G06F 12/122 (20130101) Original (OR) Class G06F 12/0246 (20130101) G06F 12/0868 (20130101) G06F 12/0897 (20130101) G06F 2212/214 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/1225 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/13 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037677 | Zhong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Xuan Zhong (Tempe, Arizona); William Yost (Scottsdale, Arizona); Michael Dorman (Scottsdale, Arizona); Julie Liss (Scottsdale, Arizona); Visar Berisha (Tempe, Arizona) |
| ABSTRACT | Disclosed herein are speech therapeutic devices and methods. In one aspect, the speech therapeutic device includes audio input circuitry, signal processing circuitry, and stimulus circuitry. In certain embodiments, the audio input circuitry is configured to provide an input signal that is indicative of speech provided by a user and the signal processing circuitry is configured to utilize a reconfigurable rule that includes a condition, receive the input signal, process the input signal using the reconfigurable rule, and provide an alert signal responsive to attainment of the condition. The stimulus circuitry is configured to receive the alert signal and provide a stimulus to the user. The signal processing circuitry is additionally configured to (i) receive the reconfigurable rule from a communication network, and/or (ii) generate a record indicative of the alert signal, store the record in a memory, and send the record to a communication network. |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 15/492105 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) Original (OR) Class Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) G09B 19/04 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/78 (20130101) G10L 2025/783 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10034638 | Ansari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Sardar Ansari (Richmond, Virginia); Kayvan Najarian (Northville, Michigan); Kevin Ward (Superior Township, Michigan) |
| ABSTRACT | Techniques for motion artifact (MA) reduction in impedance plethysmography (IP) and other physiological signals are provided. The techniques limit the amplitude of MA filtered signals by imposing an “ε-tube.” The techniques may include the introduction of a regularization term to ensure that the pattern of a filtered signal is similar to the pattern of the primary component of the original, unfiltered signal by maximizing the regularity of the filtered signal. The techniques may be integrated into a portable monitoring device, such as an armband, to remove MA from various diagnostic signals and to extract primary signal components for producing enhanced device performance. |
| FILED | Monday, February 22, 2016 |
| APPL NO | 15/049653 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/031 (20130101) A61B 5/0402 (20130101) A61B 5/0535 (20130101) A61B 5/721 (20130101) Original (OR) Class A61B 5/725 (20130101) A61B 5/0836 (20130101) A61B 5/7214 (20130101) A61B 5/7253 (20130101) A61B 8/488 (20130101) A61B 8/5223 (20130101) A61B 8/5269 (20130101) A61B 8/5276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034656 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Lianjie Huang (Los Alamos, New Mexico); Zhigang Zhang (Los Alamos, California) |
| ABSTRACT | Ultrasound tomography imaging methods for imaging a tissue medium with one or more ultrasound transducer arrays comprising a plurality of transducers, wherein said transducers comprise source transducers, receiving transducers. The methods include assigning a phase value or time delay to source transducers, exciting the transducers and calculating a search direction based on data relating to the excited transducers. |
| FILED | Thursday, July 24, 2014 |
| APPL NO | 14/339770 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/7275 (20130101) A61B 8/13 (20130101) A61B 8/14 (20130101) A61B 8/15 (20130101) A61B 8/085 (20130101) A61B 8/145 (20130101) A61B 8/406 (20130101) A61B 8/483 (20130101) A61B 8/0825 (20130101) A61B 8/4477 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8915 (20130101) G01S 15/8929 (20130101) G01S 15/8997 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 11/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10034780 | Lipsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| INVENTOR(S) | James Lipsey (Oak Park, Illinois); Jon Sensinger (Fredericton, Canada) |
| ABSTRACT | Prosthetic devices and, more particularly, modular myoelectric prosthesis components and related methods, are described. In one embodiment, a hand for a prosthetic limb may comprise a rotor-motor; a transmission, comprising a differential roller screw; a linkage coupled to the transmission; and at least one finger coupled to the linkage. In one embodiment, a component part of a wrist of a prosthetic limb may comprise an exterior-rotor motor, a planetary gear transmission, a clutch, and a cycloid transmission. In one embodiment, an elbow for a prosthetic limb may comprise an exterior-rotor motor, and a transmission comprising a planetary gear transmission, a non-backdrivable clutch, and a screw. |
| FILED | Wednesday, February 04, 2015 |
| APPL NO | 14/614187 |
| ART UNIT | 3738 — Optics |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/68 (20130101) A61F 2/72 (20130101) A61F 2/582 (20130101) Original (OR) Class A61F 2/583 (20130101) A61F 2/585 (20130101) A61F 2/586 (20130101) A61F 2002/543 (20130101) A61F 2002/587 (20130101) A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/5043 (20130101) A61F 2002/5072 (20130101) A61F 2002/6836 (20130101) A61F 2002/6845 (20130101) A61F 2002/6872 (20130101) A61F 2310/00047 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 15/0009 (20130101) B25J 15/086 (20130101) B25J 17/0258 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 15/00 (20130101) Gearing F16H 25/2252 (20130101) F16H 37/041 (20130101) F16H 2035/005 (20130101) Dynamo-electric Machines H02K 7/14 (20130101) H02K 7/116 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035175 | Gorodetsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alon Gorodetsky (Irvine, California); Long Phan (Irvine, California); David Ordinario (Irvine, California); Emil Karshalev (San Diego, California); Michael Shenk (Covina, California); Ward Gale Walkup, IV (Pasadena, California) |
| ABSTRACT | Reflectin proteins are proteins derived from cephalopods (certain species of squid) which have unusual optical properties. Disclosed herein are thin films of reflectin proteins which can be tuned to reflect infrared light. Advantageously, the films can be tuned dynamically over short time scales, to reflect at different wavelengths. Disclosed herein are novel infrared-reflective coatings, methods of making such coatings, and infrared-reflective objects such as textiles, building materials, and camouflage materials. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 14/723772 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 1/005 (20130101) B05D 3/12 (20130101) B05D 3/107 (20130101) Original (OR) Class B05D 5/063 (20130101) B05D 2203/00 (20130101) B05D 2401/10 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/02 (20130101) B32B 5/022 (20130101) B32B 5/024 (20130101) B32B 5/026 (20130101) B32B 9/02 (20130101) B32B 2307/416 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 189/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/10 (20130101) G02B 5/26 (20130101) G02B 5/0841 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2848 (20150115) Y10T 428/3154 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035920 | Omenetto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tufts University (Medford, Massachusetts) |
| ASSIGNEE(S) | Tufts University (Medford, Massachusetts) |
| INVENTOR(S) | Fiorenzo Omenetto (Wakefield, Massachusetts); David Kaplan (Concord, Massachusetts); Hu Tao (Medford, Massachusetts); Benedetto Marelli (Somerville, Massachusetts); Miaomiao Yang (Medford, Massachusetts) |
| ABSTRACT | The present application discloses biopolymer-based ink formulations that are useful for inkjet printing and other applications. Related methods are also disclosed. |
| FILED | Wednesday, November 27, 2013 |
| APPL NO | 14/647470 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) A61K 41/0052 (20130101) A61K 47/42 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/1535 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/04 (20130101) C09D 11/30 (20130101) Original (OR) Class C09D 11/38 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54386 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035994 | Pogue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kentucky BioProcessing, Inc. (Winston-Salem, North Carolina); Tsafrir Mor (Tempe, Arizona) |
| ASSIGNEE(S) | KENTUCKY BIOPROCESSING, INC. (Winston-Salem, North Carolina) |
| INVENTOR(S) | Greg Pogue (Austin, Texas); Ernie Hiatt (Maceo, Kentucky); Romy Kandzia (Halle, Germany); Stefan Werner (Halle, Germany); Frank Thieme (Halle, Germany); Tsafrir Mor (Tempe, Arizona); Steven Hume (Owensboro, Kentucky) |
| ABSTRACT | A new, reliable, easily scalable and reproducible method for the production of recombinant butyrylcholinesterase (rBuChE) is provided. Through the utilization of a plant transfection procedure, various plant strains have been shown to generate effective and scalable amounts of rBuChE under acceptable manufacturing processes to permit reliable levels of such enzymes for desired nerve agent protection requirements (including tetrameric products). As well, such methods in engineered plant lines have shown suitable production of these enzymes in tetramer form with glycan formation and sialylation (for terminal groups) to allow for optimal potency against organophosphorus agent exposure as well as proper immunogenic response within the plant sources. The overall production method, including the transfection and production within mammalian cells, as well as the process steps involved for such a reliable sourcing platform from plants is thus encompassed within the invention. |
| FILED | Tuesday, May 23, 2017 |
| APPL NO | 15/602622 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/18 (20130101) Original (OR) Class Enzymes C12Y 301/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036008 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jinpeng Wang (Goleta, California); Hyongsok Soh (Santa Barbara, California); Qiang Gong (Goleta, California) |
| ABSTRACT | The present disclosure provides a method for identifying one or more nucleic acid agents, e.g., aptamers, having a desired property from a mixture of candidate nucleic acid agents. The method generally includes immobilizing the mixture of candidate nucleic acid agents onto particles, wherein only a subset of the candidate nucleic acid agents are immobilized on any one of the particles, and wherein the subset is present in multiple copies. The particles are exposed to a target, and particles including candidate nucleic acid agents having the desired property are isolated. In this way, one or more nucleic acid agents having the desired property may be identified. Related compositions and nucleic acid agents identified as having one or more desired properties are also provided. |
| FILED | Thursday, November 21, 2013 |
| APPL NO | 14/647775 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1037 (20130101) C12N 15/1048 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/351 (20130101) C12N 2320/11 (20130101) C12N 2320/13 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 2541/101 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036015 | Kathju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandeep Kathju (Coraopolis, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sandeep Kathju (Coraopolis, Pennsylvania); Latha Satish (Wexford, Pennsylvania) |
| ABSTRACT | Embodiments of the present disclosure are directed to methods of treating, reducing or preventing fibrosis or scarring including administering a therapeutic molecular agent selected from the group consisting of an agent that inhibits chaperonin containing T-complex polypeptide subunit eta polypeptide (“CCT-eta”), an agent that inhibits α-Smooth Muscle Actin (“α-SMA”), or a combination thereof. In embodiments, the fibrosis may include Dupuytren's contracture, Peyronie's disease, pulmonary fibrosis, cirrhosis, interstitial lung disease or scarring alopecia. |
| FILED | Monday, January 05, 2015 |
| APPL NO | 14/589470 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036059 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David Yu Zhang (Houston, Texas); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof. |
| FILED | Tuesday, November 25, 2014 |
| APPL NO | 14/553165 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036263 | Lyders |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | David R Lyders (Middletown, Connecticut) |
| ABSTRACT | An inner platform structure of a stator vane for a gas turbine engine includes a male circumferential side opposite a female circumferential side, the male circumferential side includes a male wall received at least partially within a female wall of a neighboring stator vane at an interface with a pad at the interface. |
| FILED | Wednesday, August 19, 2015 |
| APPL NO | 14/829774 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) Original (OR) Class F01D 9/04 (20130101) F01D 25/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/941 (20130101) F05D 2300/43 (20130101) F05D 2300/501 (20130101) F05D 2300/50212 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036264 | McCaffrey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Michael G. McCaffrey (Windsor, Connecticut); Tracy A. Propheter-Hinckley (Manchester, Connecticut); Raymond Surace (Newington, Connecticut) |
| ABSTRACT | A component according to an exemplary aspect of the present disclosure includes, among other things, a shell defining an interior, a spar extending into the interior and a first flange attached to the spar. The spar is configured to pivot to change a positioning of the shell. |
| FILED | Friday, June 06, 2014 |
| APPL NO | 14/896738 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 9/02 (20130101) Original (OR) Class F01D 17/162 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/60 (20130101) F05D 2260/201 (20130101) F05D 2300/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036282 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Loi Cheng (South Windsor, Connecticut); Raymond Surace (Newington, Connecticut) |
| ABSTRACT | A vane support system includes a frame and a vane. The frame has a first end configured to engage to a first platform and a second end configured to engage a second platform, so the frame can structurally support at least one of the first platform and the second platform. The first and second ends define a vane axis therebetween. The vane is mounted to the frame about the vane axis. A gas turbine engine includes a case defining a centerline axis of the engine, an inner housing and a plurality of variable vanes. The inner housing is radially inward of the case with respect to the centerline axis. At least one of the variable vanes structurally supports the case and the inner housing in response to at least one of radial, axial or tangential loads with respect to the centerline axis. |
| FILED | Monday, May 18, 2015 |
| APPL NO | 14/715253 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/02 (20130101) F01D 9/065 (20130101) F01D 17/162 (20130101) F01D 25/24 (20130101) F01D 25/28 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 29/563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036652 | Zotov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sergey A. Zotov (Westminster, California); Brenton R. Simon (Irvine, California); Igor P. Prikhodko (Westminster, California); Alexander A. Trusov (Studio City, California); Andrei M. Shkel (Irvine, California) |
| ABSTRACT | A method for self-compensation of the bias draft of the quadrature signal of a gyroscope. The method is a combination of a variety of sub-methods, which can include quadrature compensation, can be used to achieve the highest possible stability. The calibration methods include a temperature self-sensing algorithm utilizing the drive-mode resonance frequency for calibration of thermal drift in the mechanical parameters of the system, a sideband-ratio approach for direct detection of mechanical drive-mode amplitude, modifying the AC and DC components of the amplitude gain control (AGC) for improved stability, and an approach for compensation of thermal drift in the sense-mode pick off system by utilizing mechanical quadrature. By using some or all of the four methods of calibration above, the highest level of long term in-run bias stability can be achieved. |
| FILED | Tuesday, February 24, 2015 |
| APPL NO | 14/630387 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5776 (20130101) G01C 25/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036699 | Jalali et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bahram Jalali (Los Angeles, California); Eric Diebold (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
| ABSTRACT | An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector. |
| FILED | Tuesday, August 08, 2017 |
| APPL NO | 15/672051 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 21/64 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2015/1006 (20130101) G01N 2021/6421 (20130101) G01N 2201/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036703 | Ng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kin Chiu Ng (Fresno, California); Subrata Sanyal (Eastvale, California) |
| ABSTRACT | A hand-held laser based biosensor including modular components, combining absorption spectrophotometry and molecular fluorescence spectrophotometry, and including a sample cell module having an improved absorption path length. |
| FILED | Thursday, September 21, 2017 |
| APPL NO | 15/712120 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/3103 (20130101) G01N 21/6402 (20130101) Original (OR) Class G01N 2030/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036769 | Noga et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Andrew J. Noga (Rome, New York); Daniel L. Stevens (Marcy, New York) |
| ABSTRACT | An apparatus for efficient, precise and accurate measurement of the frequency, amplitude, and phase of a single input tone frequency and/or multiple separable input tone frequencies. Tone separability can be achieved by proper selection of the parameter N, the sample length of the DFT/FFT. Application of the invention includes but is not limited to test and measurement, tone interference removal, and communications systems, where precise and accurate measurement of tonal parameters is needed. |
| FILED | Wednesday, July 20, 2016 |
| APPL NO | 15/214493 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 23/16 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036800 | Schofield, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John Paul Schofield, III (Odon, Indiana); Jack Eugene Fulton, Jr. (Elnora, Indiana); Terry Wayne Lockridge (Bloomington, Indiana) |
| ABSTRACT | Systems and methods are provided for the filtering of coherent noise signals. In an illustrative embodiment, a pulsed electronic signal receives varying phase shifts for each of its pulses prior to transmission. When coherent noise interferes with the transmitted signal, received signal receives a phase shift opposite of that applied prior to transmission such that the electronic signal is restored and the coherent noise becomes non-coherent. In another embodiment, width of each transmitted pulses can be varied prior to transmission, but a constant midpoint-to-midpoint time is maintained. After receiving a signal with coherent noise interference, the midpoints of the pulses are aligned causing the coherent noise to become non-coherent. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 14/819813 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/023 (20130101) Original (OR) Class G01S 7/292 (20130101) G01S 13/52 (20130101) G01S 13/282 (20130101) G01S 13/288 (20130101) G01S 13/931 (20130101) G01S 2013/9342 (20130101) G01S 2013/9346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036812 | Crouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Blackmore Sensors and Analytics Inc. (Bozeman, Montana); Montana State University (Bozeman, Montana) |
| ASSIGNEE(S) | Blackmore Sensors and Analytics Inc. (Bozeman, Montana); Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Stephen C. Crouch (Bozeman, Montana); Brant M. Kaylor (Merrimack, New Hampshire); Zeb W. Barber (Bozeman, Montana); Randy R. Reibel (Bozeman, Montana) |
| ABSTRACT | Laser 3D imaging techniques include splitting a laser temporally-modulated waveform of bandwidth B and duration D from a laser source into a reference beam and a target beam and directing the target beam onto a target. First data is collected, which indicates amplitude and phase of light relative to the reference beam received at each of a plurality of different times during a duration D at each optical detector of an array of one or more optical detectors perpendicular to the target beam. Steps are repeated for multiple sampling conditions, and the first data for the multiple sampling conditions are synthesized to form one or more synthesized sets. A 3D Fourier transform of each synthesized set forms a digital model of the target for each synthesized set with a down-range resolution based on the bandwidth B. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/192119 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/325 (20130101) G01S 17/895 (20130101) Original (OR) Class Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/0443 (20130101) G03H 1/0465 (20130101) G03H 1/0866 (20130101) G03H 2001/046 (20130101) G03H 2001/0445 (20130101) G03H 2001/2655 (20130101) G03H 2222/33 (20130101) G03H 2226/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036886 | Tabirian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia); Beam Engineering for Advanced Measurements Co. (Orlando, Florida) |
| ASSIGNEE(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Nelson V. Tabirian (Winter Park, Florida); Sarik R. Nersisyan (Maitland, Florida); Brian R. Kimball (Shrewsbury, Massachusetts); Diane M. Steeves (Franklin, Massachusetts) |
| ABSTRACT | Pointing and positioning system of light beams and images including a plurality of cycloidal diffractive waveplates, each waveplate capable of deviating a generally broadband light beam over a predetermined angle. The lateral translation and deviation angles of the light beams are controlled by controlling the relative distance, rotational position, and the diffraction efficiency of at least one in the plurality of waveplates. |
| FILED | Monday, January 30, 2017 |
| APPL NO | 15/419558 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1828 (20130101) G02B 5/1866 (20130101) G02B 26/0808 (20130101) Original (OR) Class G02B 27/0944 (20130101) G02B 27/4261 (20130101) G02B 27/4272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037028 | Loianno et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Giuseppe Loianno (Philadelphia, Pennsylvania); Yash Shailesh Mulgaonkar (Philadelphia, Pennsylvania); R. Vijay Kumar (Wilmington, Delaware) |
| ABSTRACT | Systems, devices, and methods for on-board sensing and control of robotic vehicles (e.g., MAVs) using commercial off-the-shelf hand-held electronic devices as a sensing and control system are provided. In one aspect, a system for controlling a micro aerial vehicle may include one or more sensors, a state estimation module in communication with the one or more sensors, the state estimation module being configured to generate an estimated pose of the micro aerial vehicle based on inputs from the one or more sensors, and a position controller in communication with the state estimation module and configured to communicate attitude commands to an attitude controller of the micro aerial vehicle. Each of the one or more sensors, the state estimation module, and the position controller may be contained in a commercial off-the-shelf hand-held electronic device that is configured to be coupled to the micro aerial vehicle. |
| FILED | Monday, July 25, 2016 |
| APPL NO | 15/218938 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/108 (20130101) B64C 2201/141 (20130101) B64C 2201/146 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/165 (20130101) G01C 21/206 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0011 (20130101) Original (OR) Class G05D 1/0038 (20130101) G05D 1/0088 (20130101) G05D 1/0808 (20130101) Traffic Control Systems G08G 5/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037398 | Brink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Markus Brink (White Plains, New York); Joy Cheng (Taipei, Taiwan); Gregory S. Doerk (Great Neck, New York); Michael A. Guillorn (Yorktown Heights, New York); Kafai Lai (Poughkeepsie, New York); Hsinyu Tsai (Yorktown Heights, New York) |
| ABSTRACT | A chemical pattern layer including an orientation control material and a prepattern material is formed over a substrate. The chemical pattern layer includes alignment-conferring features and additional masking features. A self-assembling material is applied and self-aligned over the chemical pattern layer. The polymeric block components align to the alignment-conferring features, while the alignment is not altered by the additional masking features. A first polymeric block component is removed selective to a second polymeric block component by an etch to form second polymeric block component portions having a pattern. A composite pattern of the pattern of an etch-resistant material within the chemical pattern layer and the pattern of the second polymeric block component portions can be transferred into underlying material layers employing at least another etch. |
| FILED | Thursday, April 21, 2016 |
| APPL NO | 15/134551 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5077 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037477 | Cha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Miriam Cha (Cambridge, Massachusetts); Rhonda D. Phillips (Somerville, Massachusetts); Patrick J. Wolfe (London, United Kingdom); Christ D. Richmond (Dorchester, Massachusetts) |
| ABSTRACT | Described embodiments detect changes in a scene over time using first and second images of the scene. A non-coherent intensity change detector detects large-scale changes between the first image and the second image and generates a large-scale change value for pairs of corresponding pixel locations in the first and second images. If the large-scale change value for a given pair of pixel locations reaches a threshold, a coherent change detector is used to detect small-scale changes between the first and second images. A small-scale change value is generated for the given pairs of pixel locations in the images. A composite change value is generated by combining the large-scale change value and the small-scale change value for each pixel pair. The change thresholds are used to determine whether a change in the scene has occurred over the time period. |
| FILED | Monday, June 20, 2016 |
| APPL NO | 15/187035 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00664 (20130101) G06K 9/6212 (20130101) Original (OR) Class G06K 9/6277 (20130101) G06K 2209/21 (20130101) G06K 2209/051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037498 | Correll et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Roger L. Correll (Bloomington, Indiana); Steven D. Lawyer (Elnora, Indiana); Thomas R. O'Brien (Loogootee, Indiana); James W. Evans, II (Bloomington, Indiana); M. Denise Wittmer (Odon, Indiana); Karen B. Hixson (Bloomington, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Roger L. Correll (Bloomington, Indiana); Steven D. Lawyer (Elnora, Indiana); Thomas R. O'Brien (Loogootee, Indiana); James W. Evans, II (Bloomington, Indiana); M. Denise Wittmer (Odon, Indiana); Karen B. Hixson (Bloomington, Indiana) |
| ABSTRACT | A project management system comprising a first, second, third, fourth and fifth processing sequences embodied in a computer readable medium. The first processing sequence is operable to provide a user interface to display a plurality of alert indicia corresponding to a plurality of alert status of a plurality of project requirements. The second processing sequence is operable to convert an incomplete requirement to a complete requirement upon completion of a task corresponding to the incomplete requirement. The third processing sequence is operable to determine the alert status of the requirements of the plurality of projects based on a time difference between a current date and a target date corresponding to each requirement. The fourth and fifth processing sequences are operable override the alert status based on user selections. |
| FILED | Saturday, November 21, 2009 |
| APPL NO | 12/623374 |
| ART UNIT | 3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06 (20130101) Original (OR) Class G06Q 10/0631 (20130101) G06Q 10/0633 (20130101) G06Q 10/0635 (20130101) G06Q 10/0637 (20130101) G06Q 10/06313 (20130101) G06Q 10/06316 (20130101) G06Q 50/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037832 | Hersam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Alexander L. Antaris (Evanston, Illinois); Alexander A. Green (Boston, Massachusetts) |
| ABSTRACT | The separation of single-walled carbon nanotubes (SWNTs), by electronic type using centrifugation of compositions of SWNTs and surface active block copolymers in density gradient media. |
| FILED | Monday, May 18, 2015 |
| APPL NO | 14/715078 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Flotation; Differential Sedimentation B03D 3/00 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0071 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 2202/02 (20130101) C01B 2202/22 (20130101) C01B 2202/36 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) Y10S 977/845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037896 | Weisse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Jeffrey Weisse (Palo Alto, California); Xiaolin Zheng (Palo Alto, California) |
| ABSTRACT | A fabrication method includes: (1) forming a wire array on a fabrication substrate; (2) forming a porous layer within a portion of the fabrication substrate below the wire array; (3) separating the porous layer and the wire array from a remaining portion of the fabrication substrate; and (4) affixing top ends of the wire array to a target substrate. |
| FILED | Thursday, September 26, 2013 |
| APPL NO | 14/907253 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2207/056 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00031 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/326 (20130101) Original (OR) Class H01L 21/02203 (20130101) H01L 21/02532 (20130101) H01L 21/02603 (20130101) H01L 29/0676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038213 | Korgel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian A. Korgel (Round Rock, Texas); Damon A. Smith (Austin, Texas); Vincent C. Holmberg (Austin, Texas); Reken Patel (Portland, Oregon); Paul Thurk (Austin, Texas) |
| ASSIGNEE(S) | Pinion Technologies, Inc. (Austin, Texas) |
| INVENTOR(S) | Brian A. Korgel (Round Rock, Texas); Damon A. Smith (Austin, Texas); Vincent C. Holmberg (Austin, Texas); Reken Patel (Portland, Oregon); Paul Thurk (Austin, Texas) |
| ABSTRACT | A method is provided for making a fabric. The method comprises (a) providing a composition comprising a plurality of nanocrystals disposed in a liquid medium, the nanocrystals comprising a material elected from the group consisting of a Group IV element; (b) applying the composition to a porous substrate, thereby removing at least a portion of the liquid medium from the nanocrystals; and (c) removing the nanocrystals from the porous substrate as a self-supporting mass. |
| FILED | Thursday, February 24, 2011 |
| APPL NO | 13/034667 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0665 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/139 (20130101) H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/405 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038345 | Georgakopoulos |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stavros Georgakopoulos (Boca Raton, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Stavros Georgakopoulos (Boca Raton, Florida) |
| ABSTRACT | A smart clothes system can include: a transmitter including a source loop, a first transmitter resonator surrounding the source loop, and a second transmitter resonator surrounding the first transmitter resonator; and a receiver including a load loop spaced apart from the source loop, a first receiver resonator surrounding the load loop, and a second receiver resonator surrounding the first receiver resonator. The transmitter can be configured to face the receiver such that it transmits power and receives data. The source loop, the first transmitter resonator, and the second transmitter resonator can be disposed on the same plane as each other, and the load loop, the first receiver resonator, and the second receiver resonator can be disposed on the same plane as each other. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/800360 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/002 (20130101) A41D 1/04 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) H02J 50/40 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038376 | Lazarus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Nathan S. Lazarus (Bethesda, Maryland); Sarah S. Bedair (Bethesda, Maryland) |
| ABSTRACT | A DC-DC power converter having a power source, a load, and a transmission line terminated at one end. A first switch is electrically connected between the power source and the second end of the transmission line. A second switch is electrically connected between the second end of the transmission line and the load and both switches are movable between an open and a closed position. A switch control circuit switches the first and second electric switches between their open and closed positions at a selected high frequency. A plurality of variable impedance elements are electrically connected to the transmission line at spaced intervals while an impedance control circuit is electrically connected to the variable impedance elements to vary the impedance of the impedance elements and thereby vary the voltage applied to the load. |
| FILED | Wednesday, August 05, 2015 |
| APPL NO | 14/818336 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/158 (20130101) Original (OR) Class H02M 2001/0058 (20130101) H02M 2001/0064 (20130101) H02M 2007/4818 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 70/1441 (20130101) Y02B 70/1491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038397 | Cline et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana); Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana); Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Curtis Harvey Cline (Brownsburg, Indiana); Michael P. Dougherty (Indianapolis, Indiana); Richard Joseph Skertic (Carmel, Indiana); Robert J. Zeller (Noblesville, Indiana) |
| ABSTRACT | A multi-engine power system is described that includes a load requiring a total amount of electrical power, a first engine configured to provide a first portion of the total amount of electrical power to be provided to the load, and a second engine configured to provide a second portion of the total amount of electrical power to be provided to the load. The system further includes a controller configured to determine the total amount of electrical power to be provided to the load, estimate a respective service time associated with each of the first and second engines, and control each of the first and second engines to provide the total amount of electrical power to the load and to coordinate the respective service times associated with the first and second engines. |
| FILED | Friday, February 24, 2017 |
| APPL NO | 15/441280 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 15/10 (20130101) F01D 21/003 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 63/04 (20130101) Controlling Combustion Engines F02D 41/22 (20130101) Dynamo-electric Machines H02K 7/1815 (20130101) H02K 7/1823 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10034656 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Lianjie Huang (Los Alamos, New Mexico); Zhigang Zhang (Los Alamos, California) |
| ABSTRACT | Ultrasound tomography imaging methods for imaging a tissue medium with one or more ultrasound transducer arrays comprising a plurality of transducers, wherein said transducers comprise source transducers, receiving transducers. The methods include assigning a phase value or time delay to source transducers, exciting the transducers and calculating a search direction based on data relating to the excited transducers. |
| FILED | Thursday, July 24, 2014 |
| APPL NO | 14/339770 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/7275 (20130101) A61B 8/13 (20130101) A61B 8/14 (20130101) A61B 8/15 (20130101) A61B 8/085 (20130101) A61B 8/145 (20130101) A61B 8/406 (20130101) A61B 8/483 (20130101) A61B 8/0825 (20130101) A61B 8/4477 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8915 (20130101) G01S 15/8929 (20130101) G01S 15/8997 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 11/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035121 | Ermanoski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Ivan Ermanoski (Albuquerque, New Mexico) |
| ABSTRACT | A thermal swing reactor including a multi-flight auger and methods for solar thermochemical reactions are disclosed. The reactor includes a multi-flight auger having different helix portions having different pitch. Embodiments of reactors include at least two distinct reactor portions between which there is at least a pressure differential. In embodiments, reactive particles are exchanged between portions during a reaction cycle to thermally reduce the particles at first conditions and oxidize the particles at second conditions to produce chemical work from heat. |
| FILED | Monday, January 30, 2017 |
| APPL NO | 15/419817 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/087 (20130101) Original (OR) Class B01J 19/127 (20130101) B01J 2219/0875 (20130101) B01J 2219/0892 (20130101) B01J 2219/1203 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 33/14 (20130101) B65G 33/20 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/042 (20130101) C01B 3/063 (20130101) C01B 32/40 (20170801) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/364 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10035127 — Metal-organic frameworks with a high density of highly charged exposed metal cation sites
| US 10035127 | Long et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeffrey R. Long (Oakland, California); Matthew T. Kapelewski (Berkeley, California); Stephen J. Geier (Sackville, Canada) |
| ABSTRACT | The disclosure provides for Metal-Organic Frameworks comprising M2 (m-dobdc)-based cores, and methods of use thereof, including gas separation, gas storage, sensing, and other applications utilizing a high density of exposed metal cation sites. |
| FILED | Tuesday, November 04, 2014 |
| APPL NO | 15/033748 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 53/04 (20130101) B01D 2253/204 (20130101) B01D 2257/108 (20130101) B01D 2258/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Original (OR) Class B01J 20/28066 (20130101) B01J 31/1691 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/0015 (20130101) Acyclic or Carbocyclic Compounds C07C 65/03 (20130101) C07C 65/05 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/328 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035499 | Lovelady |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Consolidated Nuclear Security, LLC (Reston, Virginia) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Michael Wayne Joseph Lovelady (Kingston, Tennessee) |
| ABSTRACT | A stabilizing chock assembly for a caster wheel or the like, including: a first stabilizing member or piece and a second stabilizing member or piece; and a clamping mechanism coupling the first stabilizing member to the second stabilizing member, the clamping mechanism operable for selectively biasing the first stabilizing member and the second stabilizing member together about a wheel; wherein the first stabilizing member and the second stabilizing member collectively define a conformal recess that is configured to selectively receive and retain a lower portion of the wheel. Optionally, the first stabilizing member and the second stabilizing member each define an arcuate ramp structure that forms a portion of the conformal recess. Optionally, the chock assembly also includes a friction surface disposed on a bottom surface of each of the first stabilizing member and the second stabilizing member. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/253211 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Vehicle Brake Control Systems or Parts Thereof; Brake Control Systems or Parts Thereof, in General; Arrangement of Braking Elements on Vehicles in General; Portable Devices for Preventing Unwanted Movement of Vehicles; Vehicle Modifications to Facilitate Cooling of Brakes B60T 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035828 | Schnorr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Kirk Schnorr (Holte, Denmark); Randall Kramer (Lincoln, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Thursday, July 06, 2017 |
| APPL NO | 15/642988 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/37 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10035999 — Host cell capable of producing enzymes useful for degradation of lignocellulosic material
| US 10035999 | Los et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DSM IP ASSETS B.V. (Heerlen, Netherlands) |
| ASSIGNEE(S) | DSM IP ASSETS B.V. (Heerlen, Netherlands) |
| INVENTOR(S) | Alrik Pieter Los (Echt, Netherlands); Cornelis Maria Jacobus Sagt (Echt, Netherlands); Margot Elisabeth Francoise Schooneveld-Bergmans (Echt, Netherlands); Robbertus Antonius Damveld (Echt, Netherlands) |
| ABSTRACT | The invention relates to a host cell comprising at least four different heterologous polynucleotides chose from the group of polynucleotides encoding cellulases, hemicellulases and pectinases, wherein the host cell is capable of producing the at least four different enzymes chosen from the group of cellulases, hemicellulases and pectinases, wherein the host cell is a filam-tous fungus and is capable of secretion of the at least four different enzymes. This host cell can suitably be used for the production of an enzyme composition that can be use in a process for the saccharification of cellulosic material. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/815653 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/244 (20130101) C12N 9/2437 (20130101) Original (OR) Class C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) Enzymes C12Y 302/01006 (20130101) C12Y 302/01021 (20130101) C12Y 302/01091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036049 | Shaghasi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Tarana Shaghasi (Dixon, California); Brett McBrayer (Sacramento, California) |
| ABSTRACT | The present invention relates to methods for degrading or converting a cellulosic material and for producing substances from the cellulosic material under high temperature conditions. |
| FILED | Thursday, September 28, 2017 |
| APPL NO | 15/718363 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/37 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) Original (OR) Class C12P 19/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036050 | Wogulis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Mark Wogulis (Davis, California) |
| ABSTRACT | The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants. |
| FILED | Thursday, December 20, 2012 |
| APPL NO | 14/367182 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/14 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2203/00 (20130101) Enzymes C12Y 302/01091 (20130101) C12Y 302/01176 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 31/226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036051 | Adney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | William S. Adney (Pittsboro, North Carolina); Gregg T. Beckham (Golden, Colorado); Eric Jarvis (Boulder, Colorado); Michael E. Himmel (Littleton, Colorado); Stephen R. Decker (Berthoud, Colorado); Jeffrey G. Linger (Denver, Colorado); Kara Podkaminer (Boulder, Colorado); John O. Baker (Golden, Colorado); Larry Taylor, II (Berthoud, Colorado); Qi Xu (Lakewood, Colorado); Arjun Singh (Lakewood, Colorado) |
| ABSTRACT | Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in hosts such as fungi, which in turn may be cultured to produce chimeric polypeptides. Also disclosed are chimeric polypeptides and their use in the degradation of cellulosic materials. |
| FILED | Friday, May 12, 2017 |
| APPL NO | 15/594031 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) C10L 2290/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 19/14 (20130101) Original (OR) Class Enzymes C12Y 302/01004 (20130101) C12Y 302/01021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036055 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kun Zhang (Brighton, Massachusetts); Joseph Chou (Jamaica Plain, Massachusetts) |
| ABSTRACT | Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided. |
| FILED | Thursday, May 22, 2014 |
| APPL NO | 14/284764 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2535/113 (20130101) C12Q 2535/113 (20130101) C12Q 2535/113 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036072 | Parks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jerry M. Parks (Knoxville, Tennessee); Alexander Johs (Knoxville, Tennessee) |
| ABSTRACT | Two genes required for this mercury methylation have been identified in bacteria and archaea. These genes are the hgcA gene and hgcB, a corrinoid protein that facilitates methyl group transfer to Hg, and a corrinoid protein-associated ferredoxin with two [4Fe-4S] binding motifs involved in generating cob(I)almin, respectively. The invention provides nucleic acid probes and primers for detecting methylmercury and or for assessing mercury methylation potential in environmental, clinical and other samples. The invention also provides antibodies against these proteins, antibodies against these proteins, methods of using the antibodies and methods of biocatalysis. |
| FILED | Wednesday, December 18, 2013 |
| APPL NO | 14/132906 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 2600/142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036099 | D'Evelyn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SLT TECHNOLOGIES, INC. (Los Angeles, California) |
| ASSIGNEE(S) | SLT TECHNOLOGIES, INC. (Los Angeles, California) |
| INVENTOR(S) | Mark P. D'Evelyn (Santa Barbara, California); Dirk Ehrentraut (Santa Barbara, California); Derrick S. Kamber (Goleta, California); Bradley C. Downey (Santa Barbara, California) |
| ABSTRACT | Large-scale manufacturing of gallium nitride boules using m-plane or wedge-shaped seed crystals can be accomplished using ammonothermal growth methods. Large-area single crystal seed plates are suspended in a rack, placed in a large diameter autoclave or internally-heated high pressure apparatus along with ammonia and a mineralizer, and crystals are grown ammonothermally. The orientation of the m-plane or wedge-shaped seed crystals are chosen to provide efficient utilization of the seed plates and of the volume inside the autoclave or high pressure apparatus. |
| FILED | Friday, January 16, 2015 |
| APPL NO | 14/599335 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/008 (20130101) B01J 3/042 (20130101) B01J 3/065 (20130101) B01J 2203/068 (20130101) B01J 2203/0665 (20130101) Presses in General B30B 11/002 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/105 (20130101) Original (OR) Class C30B 29/406 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02035 (20130101) H01L 21/02389 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036232 | DeWitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Foro Energy Inc. (Littleton, Colorado) |
| ASSIGNEE(S) | Foro Energy (Houston, Texas) |
| INVENTOR(S) | Ronald A. DeWitt (Katy, Texas); Mark S. Zediker (Castle Rock, Colorado); Brian O. Faircloth (Evergreen, Colorado); Daryl L. Grubb (Houston, Texas); Ryan P. McKay (Littleton, Colorado); William C. Gray (Parker, Colorado); Joel F. Moxley (Denver, Colorado); Charles C. Rinzler (Denver, Colorado); Lance D. Underwood (Morrison, Colorado); Paul D. Deutch (Houston, Texas) |
| ABSTRACT | There is provided a mobile high power laser system and conveyance structure for delivering high power laser energy to and for performing high power laser operations in remote and difficult to access locations. There is further provide such systems with high power laser, handling equipment and conveyance equipment that are configured to avoid exceeding the maximum bending radius of high power optical fibers used with the conveyance structures. There are also provided embodiments of the conveyance structures having channels, lines and passages for delivering materials such as fluids. |
| FILED | Monday, October 21, 2013 |
| APPL NO | 14/058681 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 7/14 (20130101) E21B 7/15 (20130101) E21B 10/60 (20130101) E21B 29/00 (20130101) E21B 37/00 (20130101) E21B 41/00 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/44 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036279 | Ertas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Bugra Han Ertas (Niskayuna, New York); Joshua Tyler Mook (Loveland, Ohio); Jason Joseph Bellardi (Cincinnati, Ohio) |
| ABSTRACT | A bearing including a bearing pad and a housing is provided. The bearing pad has a thrust face for supporting a vibration along an axial direction of the bearing. Additionally, the housing is formed integrally using an additive manufacturing process and is attached to or formed integrally with the bearing pad. The housing defines a working gas delivery system for providing a flow of pressurized working gas to the thrust face of the bearing pad and a fluid damper cavity. The fluid damper cavity provides a dampening of the axial vibration supported by the thrust face of the bearing pad along the axial direction. |
| FILED | Monday, April 18, 2016 |
| APPL NO | 15/131173 |
| ART UNIT | 3656 — Material and Article Handling |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/164 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/52 (20130101) F05D 2240/53 (20130101) F05D 2260/96 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 17/047 (20130101) F16C 27/02 (20130101) F16C 32/0614 (20130101) F16C 32/0622 (20130101) F16C 32/0666 (20130101) F16C 32/0677 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036356 | Svensson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Caterpillar Inc. (Peoria, Illinois) |
| ASSIGNEE(S) | Caterpillar Inc. (Deerfield, Illinois) |
| INVENTOR(S) | Kenth Svensson (Peoria, Illinois) |
| ABSTRACT | A ducted combustion system is disclosed. The ducted combustion system includes a combustion chamber bound by a flame deck surface of a cylinder head of an internal combustion engine and by a piston top surface of a piston disposed within the internal combustion engine. The system includes a fuel injector including one or more orifices, the one or more orifices injecting fuel into the combustion chamber as at least one fuel jet. The system includes at least one duct disposed within the combustion chamber between the flame deck surface and the piston top surface, the at least one duct including one or more structural tabs proximate to an outlet of the at least one duct and being disposed such that the at least one fuel jet, at least partially, enters one of the at least one duct upon being injected into the combustion chamber. |
| FILED | Thursday, December 08, 2016 |
| APPL NO | 15/373055 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 55/00 (20130101) Original (OR) Class F02M 61/14 (20130101) F02M 61/182 (20130101) F02M 61/1806 (20130101) F02M 61/1833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036581 | Koplow |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jeffrey P. Koplow (San Ramon, California) |
| ABSTRACT | Embodiments of the invention are directed to heat exchanger assemblies, systems, and methods for conditioning medium in an environment (e.g., in a controlled environment) to a suitable temperature. In particular, embodiments may include heat transfer assemblies and medium conditioning systems that may condition the medium in the environment by raising or lowering temperature thereof to a suitable conditioned temperature. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/295137 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/04 (20130101) Original (OR) Class F25B 2321/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036616 | Gash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Alexander E. Gash (Brentwood, California); Eric B. Duoss (Dublin, California); Joshua D. Kuntz (Livermore, California); Kyle T. Sullivan (Pleasanton, California); John Vericella (Oakland, California); Bradley W. White (Livermore, California) |
| ABSTRACT | A system that provides control of the output shockwave properties of energetic material wherein the system includes an energetic material having a first portion and a second portion. An additive manufacturing system combines the first portion and the second portion of the energetic material wherein the first portion and the second portion are positioned relative to each other to provide control of the output shockwave properties of the energetic material. |
| FILED | Tuesday, February 23, 2016 |
| APPL NO | 15/050974 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/02 (20130101) Original (OR) Class F42B 1/036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036779 | Sazhin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Sergiy V Sazhin (Idaho Falls, Idaho); Eric J Dufek (Ammon, Idaho); Kevin L Gering (Idaho Falls, Idaho) |
| ABSTRACT | Systems and methods for determining self-discharge currents in an energy storage cell and detecting internal shorts are disclosed. A system includes a DC voltage source configured to provide a constant test voltage selected to be less than an open-circuit voltage of an energy storage cell to the energy storage cell. The system also includes a current measuring device operably coupled between the DC voltage source and the energy storage cell, and control circuitry operably coupled to the current measuring device. A method includes applying the constant test voltage, and measuring the test current flowing between the DC voltage source and the energy storage cell until after the test current switches from a negative current to a positive current. The method also includes determining a self-discharge current of the energy storage cell by analyzing the measured test current with computational models that capture physical processes tied to the test methods. |
| FILED | Monday, November 30, 2015 |
| APPL NO | 14/954446 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/003 (20130101) G01R 31/025 (20130101) G01R 31/3606 (20130101) Original (OR) Class G01R 31/3648 (20130101) G01R 31/3658 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036878 | Greschik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | L'Garde, Inc. (Tustin, California) |
| ASSIGNEE(S) | L'Garde, Inc. (Tustin, California) |
| INVENTOR(S) | Gyula Greschik (Boulder, Colorado); Arthur L. Palisoc (Irvine, California) |
| ABSTRACT | Systems and methods are described herein that may be used to form a heliostat. Various reflective surfaces and support structures are described that permit lightweight construction of configurable heliostats. |
| FILED | Monday, March 09, 2015 |
| APPL NO | 14/642640 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Producing or Use of Heat Not Otherwise Provided For F24J 2/16 (20130101) F24J 2/52 (20130101) F24J 2/526 (20130101) F24J 2/1057 (20130101) F24J 2002/522 (20130101) F24J 2002/4689 (20130101) F24J 2002/5213 (20130101) Optical Elements, Systems, or Apparatus G02B 5/09 (20130101) G02B 5/0808 (20130101) G02B 7/183 (20130101) G02B 19/0019 (20130101) G02B 19/0042 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037203 | Chavez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Adrian R. Chavez (Davis, California); Kandy Phan (Albuquerque, New Mexico); Jasenko Hosic (Seattle, Washington); Ryan Michael Birmingham (Albuquerque, New Mexico); Jaykumar D. Patel (Albuquerque, New Mexico) |
| ABSTRACT | The various technologies presented herein relate to upgrading industrial control software in real-time. During utilization of a first software to control an industrial process, a determination can be made that the first software needs to be replaced (e.g., partially or entirely) owing to a newer version of software is ready to be deployed, a vulnerability in the first software has been determined, etc. Rather than closing the industrial process down while the first software is replaced, a second software can be deployed such that the first software and the second software are operating in parallel (e.g., receiving the same operational data, process states). When a critical point (upgrade location) in the first software has been reached, control of the industrial process can be switched to the second software, thereby enabling control of the industrial process to occur without having to temporarily cease operation and/or monitoring of the industrial process. |
| FILED | Thursday, July 28, 2016 |
| APPL NO | 15/221843 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/65 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037395 | Subramanian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Venkat Subramanian (St. Louis, Missouri); Venkatasailanathan Ramdesigan (Mumbai, India); Paul Northrop (St. Louis, Missouri); Sumitava De (St. Louis, Missouri); Bharat Kumar Suthar (St. Louis, Missouri); Matthew Lawder (St. Louis, Missouri) |
| ABSTRACT | A computer-implemented method for modeling the amount of current discharged by a battery is provided. The method is implemented by a computing device communicatively coupled with a memory, and includes generating, by the computing device, a model of at least one battery cell comprising a positive electrode region, a negative electrode region, and a separator region. The method also includes transforming the positive electrode region, the negative electrode region, and the separator region of the battery into a single region in the model. In addition, the method includes generating, by the computing device, a plurality of trial functions associated with the single region, and determining, by the computing device, the amount of current discharged from the battery cell based on the trial functions. |
| FILED | Wednesday, November 13, 2013 |
| APPL NO | 14/079490 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037855 | Ruoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Rodney S. Ruoff (Busan, South Korea); Li Li Zhang (Jurong Island, Singapore); Meryl D. Stoller (Austin, Texas) |
| ABSTRACT | Doped activated microwave expanded graphite oxide materials and doped monolayer graphene materials, and methods of making these materials. The materials exhibit increased capacitance relative to undoped activated microwave expanded graphite oxide and monolayer graphene. The materials are suitable for use in, for example, ultracapacitors. |
| FILED | Tuesday, February 23, 2016 |
| APPL NO | 15/051350 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/043 (20130101) C01B 31/0453 (20130101) C01B 31/0484 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) H01G 11/34 (20130101) Original (OR) Class H01G 11/36 (20130101) H01G 11/68 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/583 (20130101) H01M 4/624 (20130101) H01M 4/8673 (20130101) H01M 4/9083 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038113 | Nelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jeffrey S. Nelson (Albuquerque, New Mexico); Michael Hibbs (Albuquerque, New Mexico); Gregory N. Nielson (Lehi, Utah); Murat Okandan (Edgewood, New Mexico); Jose Luis Cruz-Campa (Albuquerque, New Mexico); Paul J. Resnick (Albuquerque, New Mexico); Carlos Anthony Sanchez (Beten, New Mexico); Vipin P. Gupta (Reno, Nevada); Peggy J. Clews (Tijeras, New Mexico) |
| ABSTRACT | A moldable photovoltaic module is provided. The module includes a flexible polymeric flex-circuit substrate having an electrically conductive printed wiring pattern and solder pads defined on it. Small photovoltaic cells are affixed to the flex-circuit substrate by back-surface contacts in electrical contact with the solder pads. At least one thermoformable polymeric film is joined to the flex-circuit substrate. Each said solder pad comprises a solder composition that, after an initial melt, has a melting point that lies above at least a portion of the temperature range for thermoforming the polymeric film. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950763 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/048 (20130101) H01L 31/0465 (20141201) H01L 31/0512 (20130101) H01L 31/0516 (20130101) Original (OR) Class H01L 31/022441 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 30/20 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038131 | Melsert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Southern Research Institute (Birmingham, Alabama) |
| ASSIGNEE(S) | SOUTHERN RESEARCH INSTITUTE (Birmingham, Alabama) |
| INVENTOR(S) | Ryan Melsert (Reno, Nevada); Jay Renew (Kennesaw, Georgia) |
| ABSTRACT | Disclosed herein is a method and apparatus that uses a brine from a well that is used to both generate electricity and recover valuable minerals present in the brine. The method and apparatus uses a hydrophobic membrane to separate water vapor from the brine to concentrate the brine that is then used to recover the minerals. |
| FILED | Tuesday, April 26, 2016 |
| APPL NO | 15/138554 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/12 (20130101) B01D 21/00 (20130101) B01D 61/58 (20130101) B01D 61/362 (20130101) B01D 61/366 (20130101) B01D 69/02 (20130101) B01D 71/02 (20130101) B01D 71/06 (20130101) B01D 2325/38 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/00 (20130101) C01D 15/08 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 5/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/52 (20130101) C02F 1/281 (20130101) C02F 1/448 (20130101) C02F 2101/10 (20130101) C02F 2103/34 (20130101) C02F 2303/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10034960 | Fisher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Children's National Medical Center (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | John Patrick Fisher (Kensington, Maryland); Anthony Melchiorri (Ellicott City, Maryland); Narutoshi Hibino (Columbus, Ohio); Axel Krieger (Alexandria, Virginia); John P. Costello (Washington, District of Columbia); Carolyn Cochenour (Washington, District of Columbia) |
| ABSTRACT | A composition including PPF or a PPF copolymer that can be used to fabricate biodegradable structures. The composition can be used in 3-D patterning (e.g., 3-D printing and sterolighography) methods. For example, 3-D patternable compositions include PPF or a PPF copolymer, a photoinitiator or photoinitiators, and a resolution control inhibitor or inhibitors. The compositions can be used to make biodegradable structures (such as cardivascular scaffolds). The biodegradable structures can be surface functionalized. The biodegradable structures can be used in methods of blood delivery in an individual. |
| FILED | Friday, June 06, 2014 |
| APPL NO | 14/895617 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) Original (OR) Class A61L 27/22 (20130101) A61L 27/26 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/507 (20130101) A61L 2300/252 (20130101) A61L 2300/256 (20130101) A61L 2300/414 (20130101) A61L 2430/20 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 267/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/918 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/04 (20130101) C08K 5/092 (20130101) C08K 5/132 (20130101) C08K 5/5397 (20130101) Compositions of Macromolecular Compounds C08L 67/06 (20130101) C08L 67/06 (20130101) C08L 67/06 (20130101) C08L 67/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035175 | Gorodetsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alon Gorodetsky (Irvine, California); Long Phan (Irvine, California); David Ordinario (Irvine, California); Emil Karshalev (San Diego, California); Michael Shenk (Covina, California); Ward Gale Walkup, IV (Pasadena, California) |
| ABSTRACT | Reflectin proteins are proteins derived from cephalopods (certain species of squid) which have unusual optical properties. Disclosed herein are thin films of reflectin proteins which can be tuned to reflect infrared light. Advantageously, the films can be tuned dynamically over short time scales, to reflect at different wavelengths. Disclosed herein are novel infrared-reflective coatings, methods of making such coatings, and infrared-reflective objects such as textiles, building materials, and camouflage materials. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 14/723772 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 1/005 (20130101) B05D 3/12 (20130101) B05D 3/107 (20130101) Original (OR) Class B05D 5/063 (20130101) B05D 2203/00 (20130101) B05D 2401/10 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/02 (20130101) B32B 5/022 (20130101) B32B 5/024 (20130101) B32B 5/026 (20130101) B32B 9/02 (20130101) B32B 2307/416 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 189/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/10 (20130101) G02B 5/26 (20130101) G02B 5/0841 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2848 (20150115) Y10T 428/3154 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035220 | Beuth, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jack Lee Beuth, Jr. (Pittsburgh, Pennsylvania); Jason Cho Fox (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method includes conducting a plurality of tests on process variables of a manufacturing process, with a test of the plurality of tests being associated with two combinations of process variables, the test having first values for a first combination of process variables at a first time and second values for a second combination of process variables at a second time, the test comprising: locally heating a region of a structure, wherein the local heating results in formation of a thermal field in the structure; assessing one or more thermal characteristics of the thermal field during a transition between the first combination of process variables and the second combination of process variables; and based on results of the plurality of tests, generating a process map of a transient response of the one or more thermal characteristics of the thermal field. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776445 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 31/02 (20130101) B23K 31/12 (20130101) Original (OR) Class B23K 2203/14 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/0077 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035714 | Perales-Perez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oscar Juan Perales-Perez (Mayaguez, Puerto Rico); Felix Roberto Roman-Velasquez (Mayaguez, Puerto Rico); Sonia Janet Bailon-Ruiz (Mayaguez, Puerto Rico); Luis Alberto Alamo-Nole (Mayaguez, Puerto Rico) |
| ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
| INVENTOR(S) | Oscar Juan Perales-Perez (Mayaguez, Puerto Rico); Felix Roberto Roman-Velasquez (Mayaguez, Puerto Rico); Sonia Janet Bailon-Ruiz (Mayaguez, Puerto Rico); Luis Alberto Alamo-Nole (Mayaguez, Puerto Rico) |
| ABSTRACT | Quantum dots of Cd (Se,S) and fluorescent magnetic nanocomposites (Cd (Se,S)-Magnetite) were used as photocatalyst agent in the photodegradation of methylene blue (MB) under UV irradiation at pH 6.5. A degradation of 99.1% and 90.0% of MB was achieved in presence of 160 mg/L-quantum dots and magnetic nanocomposite, respectively, after 4.5 hours of UV-irradiation. Instead, 45.9% and 100% of MB degradation was achieved using 160 mg/L of TiO2 anatase and aeroxide P25, respectively. The reuse of the magnetic nanocomposites allowed a maximum photo-degradation capacity of 65%. |
| FILED | Thursday, February 27, 2014 |
| APPL NO | 14/192786 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 2101/26 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/26 (20130101) B01J 2231/005 (20130101) B01J 2531/27 (20130101) B01J 2531/842 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) Original (OR) Class C02F 1/74 (20130101) C02F 1/488 (20130101) C02F 2101/308 (20130101) C02F 2305/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035871 | Langer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert S. Langer (Newton, Massachusetts); Jeffrey M. Karp (Brookline, Massachusetts); Maria Jose Maio Nunes-Pereira (Cambridge, Massachusetts); Ben Ouyang (Bedford, Massachusetts); Lino Da Silva Ferreira (Coimbra, Portugal); Debanjan Sarkar (Williamsville, New York) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Biocant-Center of Innovation and Biotechnology (Cantanhede, Portugal) |
| INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Jeffrey M. Karp (Brookline, Massachusetts); Maria Jose Maio Nunes-Pereira (Cambridge, Massachusetts); Ben Ouyang (Bedford, Massachusetts); Lino Da Silva Ferreira (Coimbra, Portugal); Debanjan Sarkar (Williamsville, New York) |
| ABSTRACT | Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B—)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink. |
| FILED | Sunday, August 26, 2012 |
| APPL NO | 13/594834 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/14 (20130101) C08G 18/4236 (20130101) Original (OR) Class C08G 18/4238 (20130101) C08G 18/4283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035980 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| ASSIGNEE(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | Yan Li (Tallahassee, Florida); Teng Ma (Tallahassee, Florida); Sebastien Sart (Tallahassee, Florida) |
| ABSTRACT | The subject invention pertains to acellular extracellular matrix (ECM) and methods for preparing it. In one embodiment, the ECM is prepared from 3-D aggregates of pluripotent stem cells or from embryoid bodies. In one embodiment, the ECM is in the form of acellular microspheres. The stem cells used in the present invention can be embryonic stem cells (ESC). In a specific embodiment, the stem cells or embryoid bodies are from human. The ECM of the invention can be mass produced using PSC aggregates or embryoid bodies in large scale bioreactors. The acellular ECM produced using the present invention can be used for injection into a person or animal to regenerate tissue and/or treat a disease or condition. A method of the invention comprises growing stem cells in suspension culture as aggregates, e.g., in a bioreactor. Acellular ECM is then prepared from the cell aggregates by decellularization. In a specific embodiment, a decellularization reagent comprising Triton X-100 is used, followed by treatment with a DNase. |
| FILED | Tuesday, January 14, 2014 |
| APPL NO | 14/760945 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/12 (20130101) A61K 35/545 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/50 (20130101) A61L 27/365 (20130101) A61L 27/3633 (20130101) A61L 27/3675 (20130101) A61L 27/3834 (20130101) A61L 27/3895 (20130101) A61L 2300/64 (20130101) A61L 2300/412 (20130101) A61L 2430/02 (20130101) A61L 2430/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class C12N 5/0606 (20130101) C12N 2501/155 (20130101) C12N 2501/235 (20130101) C12N 2513/00 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036034 | Walia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Harkamal Walia (Lincoln, Nebraska); Dante Placido (Oakland, Nebraska); Thomas E. Clemente (Lincoln, Nebraska) |
| ABSTRACT | Nucleic acid sequences involved in plant yield are provided, as are methods of using such nucleic acid sequences. |
| FILED | Friday, December 05, 2014 |
| APPL NO | 14/562182 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) Edible Oils or Fats, e.g Margarines, Shortenings, Cooking Oils A23D 9/00 (20130101) Fodder A23K 10/00 (20160501) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 7/10 (20160801) A23L 7/198 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/01 (20130101) C12N 15/8261 (20130101) C12N 15/8273 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2600/13 (20130101) C12Q 2600/156 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036059 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David Yu Zhang (Houston, Texas); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof. |
| FILED | Tuesday, November 25, 2014 |
| APPL NO | 14/553165 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036735 | Piestun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Colorado, A Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| INVENTOR(S) | Rafael Piestun (Boulder, Colorado); Hengyi Ju (Boulder, Colorado); Jacob Dove (Boulder, Colorado); Antonio Miguel Caravaca-Aguirre (Boulder, Colorado); Todd Murray (Golden, Colorado); Donald Conkey (Boulder, Colorado) |
| ABSTRACT | Systems and methods are disclosed to enhance three-dimensional photoacoustic imaging behind, through, or inside a scattering material. Some embodiments can increase the optical fluence in an ultrasound transducer focus and/or enhance the optical intensity using wavefront shaping before the scatterer. The photoacoustic signal induced by an object placed behind the scattering medium can serve as feedback to optimize the wavefront, enabling one order of magnitude enhancement of the photoacoustic amplitude. Using the enhanced optical intensity, the object can be scanned in two dimensions and/or a spot can be scanned by re-optimizing the wavefront before post-processing of the data to reconstruct the image. The temporal photoacoustic signal provides information to reconstruct the third-dimensional information. |
| FILED | Tuesday, August 26, 2014 |
| APPL NO | 14/913958 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0095 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 29/0654 (20130101) G01N 29/2418 (20130101) Original (OR) Class G01N 2021/1706 (20130101) G01N 2201/0675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036747 | Pancer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Zeev Pancer (Baltimore, Maryland); Li Mao (Clarksville, Maryland); Xia Hong (Olney, Maryland); Mark Z. Ma (Ellicott City, Maryland) |
| ABSTRACT | The invention relates to dimeric proteins comprised of subunits having (i) recombinant lamprey variable lymphocyte receptor (VLR) diversity regions linked to (ii) multimerization domains. The dimeric proteins exhibit binding specificity for glycosylated antigens, and they may be used in methods of detecting or isolating glycans from a sample, and in methods of disease diagnosis, prognosis, progression monitoring, treatment, and imaging. |
| FILED | Wednesday, November 21, 2012 |
| APPL NO | 14/359653 |
| ART UNIT | 1678 — Optics |
| CURRENT CPC | Peptides C07K 14/461 (20130101) C07K 2319/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) Original (OR) Class G01N 33/574 (20130101) G01N 33/5308 (20130101) G01N 2400/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036773 | Ghosh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Swaroop Ghosh (Tampa, Florida); Cheng-Wei Lin (Seffner, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Swaroop Ghosh (Tampa, Florida); Cheng-Wei Lin (Seffner, Florida) |
| ABSTRACT | Various devices, methods and systems are provided for aging-sensitive chip authentication. In one example, among others, a chip includes a reference Schmitt trigger ring oscillator (STRO) configured to enter a sleep mode during operation of the chip; a stressed STRO; a VDD charge pump configured to boost a positive voltage supplied to the stressed STRO during operation of the chip; and a GND charge pump configured to under-drive a ground voltage supplied to the stressed STRO during operation of the chip. In another example, a method includes detecting activation of a chip including a reference STRO and a stressed STRO and, in response to the activation of the chip, initiating sleep mode operation of the reference STRO. In response to the activation of the chip, a VDD voltage supplied to the stressed STRO can be boosted and/or a GND voltage supplied to the stressed STRO can be under-driven. |
| FILED | Friday, December 11, 2015 |
| APPL NO | 14/966224 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 23/02 (20130101) G01R 31/282 (20130101) G01R 31/2832 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036833 | Gemici et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zekeriyya Gemici (Istanbul, Turkey); Michael F. Rubner (Westford, Massachusetts); Robert E. Cohen (Jamaica Plain, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Zekeriyya Gemici (Istanbul, Turkey); Michael F. Rubner (Westford, Massachusetts); Robert E. Cohen (Jamaica Plain, Massachusetts) |
| ABSTRACT | A superhydrophilic coating on a substrate can be antireflective and antifogging. The coating can remain antireflective and antifogging for extended periods. The coating can include oppositely charge inorganic nanoparticles, and can be substantially free of an organic polymer. The coating can be made mechanically robust by a hydrothermal calcination. |
| FILED | Tuesday, November 30, 2010 |
| APPL NO | 12/956913 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/006 (20130101) C03C 17/3411 (20130101) C03C 2217/42 (20130101) C03C 2217/75 (20130101) C03C 2217/734 (20130101) C03C 2218/11 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 5/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/18 (20150115) G02B 1/118 (20130101) Original (OR) Class G02B 27/0006 (20130101) G02B 2207/101 (20130101) G02B 2207/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036885 | Abbott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Richard Abbott (Altadena, California); Peter Fritschel (Cambridge, Massachusetts) |
| ABSTRACT | An electro-mechanical shutter is described. The fast operation is based on a coil operated via a current, where the coil can move within a set of magnets to provide opening and closing of a shutter. The shutter can comprise a mirror connected to the coil, so that the mirror can be moved into the path of an optical beam. The mirror can block the beam light in the closed state, and allow the beam light in the open state. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 14/711466 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/1821 (20130101) G02B 26/02 (20130101) G02B 26/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037285 | Ramachandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Umakishore Ramachandran (Lilburn, Georgia); Mungyung Ryu (Atlanta, Georgia) |
| ABSTRACT | The disclosed technology includes techniques for efficiently streaming media content from a multi-tiered storage system. An example implementation may be used for adaptive HTTP streaming of video segments and other content. In some implementations, flash memory SSDs (SLC or MLC) may form an intermediate cache layer between a first layer of DRAM cache and third layer of HDDs. Significant architectural elements of various implementations include optimal write granularity to overcome the write amplification effect of flash memory SSDs and a QoS-sensitive caching strategy that monitors the activity of the flash memory SSDs to ensure that video streaming performance is not hampered by the caching activity. |
| FILED | Wednesday, January 14, 2015 |
| APPL NO | 14/597193 |
| ART UNIT | 2131 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 3/064 (20130101) G06F 3/0611 (20130101) G06F 3/0629 (20130101) G06F 12/122 (20130101) Original (OR) Class G06F 12/0246 (20130101) G06F 12/0868 (20130101) G06F 12/0897 (20130101) G06F 2212/214 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/1225 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/13 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037395 | Subramanian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Venkat Subramanian (St. Louis, Missouri); Venkatasailanathan Ramdesigan (Mumbai, India); Paul Northrop (St. Louis, Missouri); Sumitava De (St. Louis, Missouri); Bharat Kumar Suthar (St. Louis, Missouri); Matthew Lawder (St. Louis, Missouri) |
| ABSTRACT | A computer-implemented method for modeling the amount of current discharged by a battery is provided. The method is implemented by a computing device communicatively coupled with a memory, and includes generating, by the computing device, a model of at least one battery cell comprising a positive electrode region, a negative electrode region, and a separator region. The method also includes transforming the positive electrode region, the negative electrode region, and the separator region of the battery into a single region in the model. In addition, the method includes generating, by the computing device, a plurality of trial functions associated with the single region, and determining, by the computing device, the amount of current discharged from the battery cell based on the trial functions. |
| FILED | Wednesday, November 13, 2013 |
| APPL NO | 14/079490 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037832 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Alexander L. Antaris (Evanston, Illinois); Alexander A. Green (Boston, Massachusetts) |
| ABSTRACT | The separation of single-walled carbon nanotubes (SWNTs), by electronic type using centrifugation of compositions of SWNTs and surface active block copolymers in density gradient media. |
| FILED | Monday, May 18, 2015 |
| APPL NO | 14/715078 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Flotation; Differential Sedimentation B03D 3/00 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0071 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/172 (20170801) C01B 2202/02 (20130101) C01B 2202/22 (20130101) C01B 2202/36 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) Y10S 977/845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038142 | Nalwa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kanwar Singh Nalwa (Portland, Oregon); Sumit Chaudhary (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Kanwar Singh Nalwa (Portland, Oregon); Sumit Chaudhary (Ames, Iowa) |
| ABSTRACT | A method of fabricating an organic photovoltaic device. The method includes providing a first electrode which by applying a layer of conductive material onto a transparent substrate. The conductive material forms the first electrode. The method also includes placing an active layer of organic photovoltaic material on top of the first electrode. The active layer is configured to convert photonic energy into electrical energy. Placing an active layer of organic photovoltaic material includes placing an active layer of organic photovoltaic material having ferroelectric dipoles dispersed therein. The method further includes applying a second electrode on top of the active layer of organic photovoltaic material. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 15/935284 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0035 (20130101) Original (OR) Class H01L 51/0036 (20130101) H01L 51/0037 (20130101) H01L 51/424 (20130101) H01L 51/4293 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038156 | Gong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xiong Gong (Hudson, Ohio); Chang Liu (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Xiong Gong (Hudson, Ohio); Chang Liu (Akron, Ohio) |
| ABSTRACT | A broad-band photodetector utilizes perovskite hybrid material and quantum dots as light harvesters. In particular, the photodetector is configured so that the structural defects on the surface of a quantum dot layer are passivated with perovskite hybrid material. As a result, the trap states on the surface of the quantum dot material is reduced, allowing leakage currents in the quantum dot material to be significantly reduced. As such, the photodetector is able to achieve broad-band operation, with enhanced photoresponsitivity and detectivity. |
| FILED | Tuesday, August 30, 2016 |
| APPL NO | 15/251123 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0037 (20130101) H01L 51/42 (20130101) H01L 51/442 (20130101) H01L 51/447 (20130101) H01L 51/4213 (20130101) H01L 51/4246 (20130101) Original (OR) Class H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/774 (20130101) Y10S 977/813 (20130101) Y10S 977/892 (20130101) Y10S 977/954 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038199 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Hong Yang (Champaign, Illinois); Jianbo Wu (Savoy, Illinois) |
| ABSTRACT | A noble metal-based electrocatalyst comprises a bimetallic particle comprising a noble metal and a non-noble metal and having a polyhedral shape. The bimetallic particle comprises a surface-segregated composition where an atomic ratio of the noble metal to the non-noble metal is higher in a surface region and in a core region than in a sub-surface region between the surface and core regions. A method of treating a noble metal-based electrocatalyst comprises annealing a bimetallic particle comprising a noble metal and a non-noble metal and having a polyhedral shape at a temperature in the range of from about 100° C. to about 1100° C. |
| FILED | Thursday, May 11, 2017 |
| APPL NO | 15/592522 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0085 (20130101) B22F 1/0088 (20130101) B22F 2001/0037 (20130101) B22F 2301/15 (20130101) B22F 2301/25 (20130101) B22F 2304/054 (20130101) B22F 2998/10 (20130101) Alloys C22C 5/04 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/14 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/921 (20130101) Original (OR) Class H01M 4/926 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038240 | Patron et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania); Adant Technologies, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania); Adant Technologies, Inc. (Santa Clara, California) |
| INVENTOR(S) | Damiano Patron (Philadelphia, Pennsylvania); Kapil R. Dandekar (Philadelphia, Pennsylvania); Daniele Piazza (Lodi, Italy) |
| ABSTRACT | A planar reconfigurable antenna that is capable of generating omnidirectional and directional radiation patterns over a wide frequency band or over multiple frequency bands includes a substrate, one or more pairs of conductive elements on at least one side of the substrate, a common RF feed point, and respective switches that selectively connects one or all of the conductive elements to the common RF feed point. An omni-directional radiation pattern is generated when all of the conductive elements are connected to the common RF feed point, while a directional radiation pattern is generated when only a pair of conductive elements on opposite sides of the substrate are connected to the common RF feed point. In the directional radiation mode, the conductive elements that are not connected to the common RF feed point act as a reflector for other conductive elements that are connected to the common RF feed point. |
| FILED | Friday, December 20, 2013 |
| APPL NO | 14/653076 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 3/24 (20130101) Original (OR) Class H01Q 3/44 (20130101) H01Q 9/44 (20130101) H01Q 21/30 (20130101) H01Q 21/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038345 | Georgakopoulos |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stavros Georgakopoulos (Boca Raton, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Stavros Georgakopoulos (Boca Raton, Florida) |
| ABSTRACT | A smart clothes system can include: a transmitter including a source loop, a first transmitter resonator surrounding the source loop, and a second transmitter resonator surrounding the first transmitter resonator; and a receiver including a load loop spaced apart from the source loop, a first receiver resonator surrounding the load loop, and a second receiver resonator surrounding the first receiver resonator. The transmitter can be configured to face the receiver such that it transmits power and receives data. The source loop, the first transmitter resonator, and the second transmitter resonator can be disposed on the same plane as each other, and the load loop, the first receiver resonator, and the second receiver resonator can be disposed on the same plane as each other. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/800360 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/002 (20130101) A41D 1/04 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) H02J 50/40 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038446 | Mai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Kenneth Wei-An Mai (Pittsburgh, Pennsylvania); Mudit Bhargava (Pittsburgh, Pennsylvania) |
| ABSTRACT | Techniques and circuits are disclosed for obtaining a physical unclonable function (PUF) circuit that is configured to provide, during a first operational mode, an output signal that is dependent on an electric characteristic of the PUF circuit. Techniques and circuits described herein can cause the PUF circuit to enter a second operational mode by applying a stress signal to the PUF circuit that changes a value of the electric characteristic relative to another value of the electric characteristic during the first operational mode of the PUF circuit; and adjusting, based on changing the absolute value of the first electric characteristic, a bias magnitude of the output signal relative to another bias magnitude of the output signal during the first operational mode of the PUF circuit. |
| FILED | Thursday, August 21, 2014 |
| APPL NO | 14/913285 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Pulse Technique H03K 19/00315 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 9/3278 (20130101) H04L 2209/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038564 | Holcomb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Daniel E. Holcomb (Watertown, Massachusetts); Kevin Fu (Ann Arbor, Michigan) |
| ABSTRACT | A technique is presented for performing a physical unclonable function (PUF) using an array of SRAM cells. The technique can be viewed as an attempt to read multiple cells in a column at the same time, creating contention that is resolved according to process variation. An authentication challenge is issued to the array of SRAM cells by activating two or more wordlines concurrently. The response is simply the value that the SRAM produces from a read operation when the challenge condition is applied. The number of challenges that can be applied the array of SRAM cells grows exponentially with the number of SRAM rows and these challenges can be applied at any time without power cycling. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 15/684118 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) Original (OR) Class H04L 2209/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10039033 | Forte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Andrea G. Forte (Brooklyn, New York); Henning Schulzrinne (Leonia, New Jersey); Arpit Mehta (Seattle, Washington) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Andrea G. Forte (Brooklyn, New York); Henning Schulzrinne (Leonia, New Jersey); Arpit Mehta (Seattle, Washington) |
| ABSTRACT | Systems, methods, and media for implementing call handoff between networks are provided, in some embodiments, systems for implementing call handoff between networks are provided, the systems comprising: at least one device that: receives a call from a first endpoint; establishes a connection between the first endpoint and a conference; calls a second endpoint: establishes a connection between the second endpoint and the conference; and when one of the first endpoint and the second endpoint is able to be connected to a different network from a current network which the one of the first endpoint and the second endpoint is connected to the conference: establishes a connection between the conference and the one of the first endpoint and the second endpoint via the different network; and removes the connection via the current network between the one of the first endpoint and the second endpoint and the conference. |
| FILED | Monday, June 22, 2009 |
| APPL NO | 13/000328 |
| ART UNIT | 2476 — Multiplex and VoIP |
| CURRENT CPC | Wireless Communication Networks H04W 36/0016 (20130101) Original (OR) Class H04W 36/0022 (20130101) H04W 80/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10036632 | Ott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Melanie N. Ott (Columbia, Maryland); William J. Thomes (The Villages, Florida); Eleanya E. Onuma (Greenbelt, Maryland) |
| ABSTRACT | Aspects of the present disclosure involve a system and method for performing radio frequency interferometry using optical fiber sensing. Optical fiber sensing is performed as a reference signal is defined and compared, in the optical domain, to incoming signals to obtain interference fringe patterns that can be used to decode phase shift offsets with respect to the designated reference signal. The phase shift offsets can be determined by first optically modulating the reference and incoming signals using a laser source as the carrier. In the optical domain, the reference and incoming signals are combined using an optical coupler and then converted back to the electrical domain for processing. |
| FILED | Monday, November 21, 2016 |
| APPL NO | 15/356996 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02002 (20130101) G01B 15/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036700 | McElroy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Mark W. McElroy (Houston, Texas) |
| ABSTRACT | A numerical simulation tool for progressive failure in laminates utilizes a low fidelity approach. The numerical model includes an enriched element that is initially in a low fidelity form. The enriched elements may increase fidelity by splitting locally to simulate an ongoing damage process such as delamination. |
| FILED | Thursday, October 01, 2015 |
| APPL NO | 15/526369 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/00 (20130101) G01N 19/08 (20130101) Original (OR) Class G01N 2203/0025 (20130101) G01N 2203/0066 (20130101) G01N 2203/0212 (20130101) G01N 2203/0216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036784 | Shams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Qamar A. Shams (Yorktown, Virginia); John F. Sutton (Springs, West Virginia) |
| ABSTRACT | A magnetometer configured to measure low field strength magnetic fields is provided. Certain embodiments of the magnetometer include a cylindrical coil assembly having a variable permeability core and terminals disposed at both ends. A current source circuit may be operably connected to the terminals and configured to apply a voltage controlled current across the terminals. A voltage readout circuit may be operably connected to the terminals and configured to measure a voltage across the terminals due to the applied current from the current source. An inductance of the coil assembly directly varies as an ambient magnetic field strength varies a permeability of the variable permeability core, and a voltage across the terminals varies directly with the inductance such that the measured voltage across the terminals is a direct measure of the ambient magnetic field strength. |
| FILED | Wednesday, April 01, 2015 |
| APPL NO | 14/676172 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) G01R 33/028 (20130101) Original (OR) Class Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/10 (20130101) G01V 3/081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10037702 | Kashi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| INVENTOR(S) | Rajanikanth Nagaraj Kashi (Karnataka, India); Vinayak Manohar Chitragar (Karnataka, India); Sathish Pakki (Karnataka, India) |
| ABSTRACT | Methods and apparatus are provided for simulating an interval management (IM) procedure for an ownship aircraft and a target aircraft before the start of the performance of the IM procedure. The method comprises receiving an IM clearance message from air traffic control (ATC), parsing the received IM clearance message into parsed information components identifying the complexity of the IM clearance message based on the number of elements in the information components, generating a flight chart depicting the area over which the proposed IM procedure is to traverse using the mapping information wherein the flight chart includes a vertical view and a plan view, and simulating the IM procedure on the generated flight chart before any steps of the IM procedure are performed. |
| FILED | Wednesday, July 19, 2017 |
| APPL NO | 15/653838 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04842 (20130101) G06F 17/2705 (20130101) G06F 2203/04806 (20130101) Image Data Processing or Generation, in General G06T 11/001 (20130101) G06T 11/206 (20130101) G06T 13/80 (20130101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0021 (20130101) Original (OR) Class G08G 5/0039 (20130101) G08G 5/0047 (20130101) G08G 5/0082 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10039217 | Thomsen, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Donald Laurence Thomsen, III (Yorktown, Virginia); Roberto J. Cano (Yorktown, Virginia); Brian J. Jensen (Williamsburg, Virginia); Stephen J. Hales (Newport News, Virginia); Joel A. Alexa (Hampton, Virginia) |
| ABSTRACT | Disclosed are methods of building Z-graded radiation shielding and covers. In one aspect. the method includes: providing a substrate surface having about medium Z-grade; plasma spraying a first metal having higher Z-grade than the substrate surface; and infusing a polymer layer to form a laminate. In another aspect, the method includes electro/electroless plating a first metal having higher Z-grade than the substrate surface. In other aspects, the invention provides methods of improving an existing electronics enclosure to build a Z-graded radiation shield by applying a temperature controller to at least part of the enclosure and affixing at least one layer of a first metal having higher Z-grade than the enclosure. |
| FILED | Friday, August 09, 2013 |
| APPL NO | 13/963484 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10036084 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Xiaochun Li (Madison, Wisconsin); Lianyi Chen (Madison, Wisconsin); Jiaquan Xu (Madison, Wisconsin) |
| ABSTRACT | Solid immiscible alloys and methods for making the solid immiscible alloys are provided. The microstructure of the immiscible alloys is characterized by a minority phase comprising a plurality of particles of an inorganic material dispersed in a majority phase comprising a continuous matrix of another inorganic material. The methods utilize nanoparticles to control both the collisional growth and the diffusional growth of the minority phase particles in the matrix during the formation of the alloy microstructure. |
| FILED | Tuesday, November 06, 2012 |
| APPL NO | 13/669636 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/016 (20130101) Alloys C22C 1/02 (20130101) C22C 1/06 (20130101) C22C 1/026 (20130101) C22C 1/1036 (20130101) C22C 21/00 (20130101) C22C 21/003 (20130101) Original (OR) Class C22C 32/0047 (20130101) C22C 2001/1047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036683 | Moldover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| ASSIGNEE(S) | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | Michael R. Moldover (Bethesda, Maryland); Keith A. Gillis (Washington Grove, Maryland); James B. Mehl (Orcas, Washington) |
| ABSTRACT | An acousto-microwave system to determine a mass M of gas disposed in a vessel includes: a microwave transmitter disposed on the vessel to transmit microwave radiation inside the vessel, a portion of the microwave radiation occurring at a microwave resonance of the vessel; a microwave receiver disposed on the vessel to receive microwave radiation communicated through an interior of the vessel from the microwave transmitter; an acoustic transmitter disposed on the vessel to transmit acoustic radiation inside the vessel, a portion of the acoustic radiation occurring at an acoustic resonance of the gas in the vessel; and an acoustic receiver disposed on the vessel to receive acoustic radiation communicated through the gas from the acoustic transmitter. The mass M of the gas is determined by analyzing the microwave radiation received by the microwave receiver and the acoustic radiation received by the acoustic receiver. |
| FILED | Tuesday, June 21, 2016 |
| APPL NO | 15/188211 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/24 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/036 (20130101) G01N 2291/014 (20130101) G01N 2291/02809 (20130101) G01N 2291/02881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038219 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amprius, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Amprius, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Gregory Alan Roberts (Oakland, California); Rainer J. Fasching (Mill Valley, California); Constantin I. Stefan (San Jose, California) |
| ABSTRACT | Provided are novel electrolytes for use in rechargeable lithium ion cells containing high capacity active materials, such as silicon, germanium, tin, and/or aluminum. These novel electrolytes include one or more pyrocarbonates and, in certain embodiments, one or more fluorinated carbonates. For example, dimethyl pyrocarbonate (DMPC) may be combine with mono-fluoroethylene carbonate (FEC). Alternatively, DMPC or other pyrocarbonates may be used without any fluorinated carbonates. A weight ratio of pyrocarbonates may be between about 0% and 50%, for example, about 10%. Pyrocarbonates may be combined with other solvents, such as ethylene carbonate (EC), propylene carbonate (PC), dimethyl carbonate (DMC), diethyl carbonate (DEC), and/or ethyl-methyl carbonate (EMC). Alternatively, pyrocarbonates may be used without such solvents. Experimental results conducted using electrochemical cells with silicon based electrodes demonstrated substantial improvements in cycle life when pyrocarbonate containing electrolytes were used in comparison with pyrocarbonate free electrolytes. |
| FILED | Thursday, August 20, 2015 |
| APPL NO | 14/831697 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/75 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/0428 (20130101) H01M 4/483 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2300/0034 (20130101) H01M 2300/0037 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 10036560 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF ALASKA ANCHORAGE (Anchorage, Alaska); UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| ASSIGNEE(S) | University of Alaska Anchorage (Anchorage, Alaska); University of Houston System (Houston, Texas) |
| INVENTOR(S) | Zhaohui Yang (Anchorage, Alaska); Ting Yang (West Lafayette, Indiana); Gangbing Song (Pearland, Texas); Mithun Singla (Houston, Texas); Christiana Chang (Houston, Texas) |
| ABSTRACT | A system and method for heating structures to either prevent the build-up of freezing precipitation or eliminate freezing precipitation on an exposed outer surface of the structures. The system includes a heating assembly integrally formed with a structure to apply thermal energy to the exposed outer surface of the structure. Optionally, the heating assembly includes heating elements formed of carbon fiber. The system optionally includes a control assembly operatively coupled to the heating assembly. The control assembly selectively powers the heating assembly and can be configured for remote operation. In use, the control assembly can be selectively activated from a remote location to power the heating assembly and heat the structure. Optionally, the structure is a concrete structure. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809183 |
| ART UNIT | 3742 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Construction Of, or Surfaces For, Roads, Sports Grounds, or the Like; Machines or Auxiliary Tools for Construction or Repair E01C 11/265 (20130101) Domestic- or Space-heating Systems, e.g Central Heating Systems; Domestic Hot-water Supply Systems; Elements or Components Therefor F24D 13/02 (20130101) Original (OR) Class F24D 13/022 (20130101) F24D 19/1096 (20130101) F24D 2200/08 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/1934 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 3/145 (20130101) H05B 3/286 (20130101) H05B 2203/002 (20130101) H05B 2203/014 (20130101) H05B 2203/026 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036631 | Huang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yaxiong Huang (Austin, Texas) |
| ASSIGNEE(S) | Texas Department of Transportation (Austin, Texas) |
| INVENTOR(S) | Yaxiong Huang (Austin, Texas) |
| ABSTRACT | In some embodiments, a system for measuring surface features may include a patter projector, at least one digital imaging device, and an image processing device. The pattern projector may project, during use, a pattern of light on a surface of an object. In some embodiments, the pattern projector moves, during use, the pattern of light along the surface of the object. In some embodiments, the pattern projector moves the pattern of light in response to electronic control signals. At least one of the digital imaging devices may record, during use, at least one image of the projected patter of light. The image processing device which, during use, converts projected patterns of light recorded on at least one of the images to three-dimensional data points representing a surface geometry of the object using relative positions and relative angles between the at least one imaging device and the pattern projector. |
| FILED | Wednesday, May 01, 2013 |
| APPL NO | 13/874968 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/303 (20130101) Original (OR) Class G01B 11/2527 (20130101) G01B 11/2545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038201 | Ferreira et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Melo Ferreira (Glastonbury, Connecticut); Christopher John Carnevale (Vernon, Connecticut); Glenn Michael Allen (Vernon, Connecticut) |
| ASSIGNEE(S) | AUDI AG (Ingolstadt, Germany) |
| INVENTOR(S) | David Melo Ferreira (Glastonbury, Connecticut); Christopher John Carnevale (Vernon, Connecticut); Glenn Michael Allen (Vernon, Connecticut) |
| ABSTRACT | An exemplary fuel cell component includes a plate comprising an electrically conductive material. An electrical connector includes a first portion embedded in the plate. A second portion of the electrical connector extends from the plate. The second portion is configured to make an electrically conductive connection with another device. |
| FILED | Wednesday, June 13, 2012 |
| APPL NO | 13/495353 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0204 (20130101) Original (OR) Class H01M 8/249 (20130101) H01M 8/2465 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10034936 | Stapleton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | The University of Iowa Research Foundation (Iowa, Iowa); The United States of America as represented by the Secretary of the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jack T. Stapleton (Iowa City, Iowa); Jinhua Xiang (Iowa City, Iowa); Donna Klinzman (Coralville, Iowa); James H. McLinden (Coralville, Iowa) |
| ABSTRACT | GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods involving an anti-GBV-C antibody or other GBV-C binding agent, or a GBV-C antigen, for inhibiting and treating HIV infections. |
| FILED | Friday, August 15, 2014 |
| APPL NO | 14/460517 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/29 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 14/05 (20130101) C07K 14/1841 (20130101) C07K 16/109 (20130101) C07K 2317/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24222 (20130101) C12N 2770/24234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035013 | Desalles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); NEUROSIGMA, INC. (Los Angeles, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); NEUROSIGMA, INC. (Los Angeles, California) |
| INVENTOR(S) | Antonio A. F. Desalles (Los Angeles, California); Alessandra Gorgulho (Los Angeles, California); Christopher M. DeGiorgio (Valencia, California); Ian A. Cook (Los Angeles, California); Colin Kealey (Los Angeles, California); Leon Ekchian (Glendale, California); Patrick Miller (Santa Monica, California) |
| ABSTRACT | An implantable subcutaneous electrode system is disclosed. The implantable subcutaneous electrode system may include an electrode body with electrical contacts disposed thereon or integrally formed therein. The electrode body also may include an insulation region defined between the electrical contacts and an aperture defined in the electrode body for receiving an anchoring device. A minimally invasive delivery device and methods for delivery of an implantable electrode system is also provided. The methods may include steps of introducing a needle comprising a cannula and a stylet through a patient's skin, removing the stylet while leaving the cannula in place, introducing an electrode applicator through the cannula, the electrode applicator comprising a hollow driver which receives the electrode assembly, and anchoring the electrode assembly to a bone by driving the hollow driver such that a self-tapping screw within the electrode assembly screws into the bone. |
| FILED | Friday, April 05, 2013 |
| APPL NO | 14/390986 |
| ART UNIT | 3766 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3421 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0504 (20130101) A61N 1/0526 (20130101) A61N 1/0553 (20130101) A61N 1/0558 (20130101) Original (OR) Class A61N 1/36064 (20130101) A61N 1/36182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10036067 | Raskind et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wendy H. Raskind (Seattle, Washington); Dong-Hui Chen (Seattle, Washington); Thomas D. Bird (Lake Forest Park, Washington); Zoran Brkanac (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Wendy H. Raskind (Seattle, Washington); Dong-Hui Chen (Seattle, Washington); Thomas D. Bird (Lake Forest Park, Washington); Zoran Brkanac (Seattle, Washington) |
| ABSTRACT | In one aspect, the invention provides methods of identifying genetic mutations that are associated with ataxic neurological disease. The methods comprise identifying a difference between a nucleic acid sequence of a protein kinase C gamma gene from a mammalian subject exhibiting ataxia and a nucleic acid sequence of a protein kinase C gamma gene from a subject which is not exhibiting ataxia, wherein the difference is a genetic mutation associated with ataxic neurological disease. In another aspect, isolated nucleic acid molecules encoding protein kinase C gamma missense mutations are provided. In another aspect, a method of screening a subject to determine if the subject has a genetic predisposition to develop an ataxic neurological disease is provided. In another aspect, the invention provides kits for determining susceptibility or presence of ataxic neurological disease in a mammalian subject. |
| FILED | Friday, December 04, 2009 |
| APPL NO | 12/631722 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10034932 | Olsen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Christopher W. Olsen (Madison, Wisconsin); Gabriele A. Landolt (Fort Collins, Colorado); Alexander I. Karasin (Madison, Wisconsin) |
| ABSTRACT | The invention provides an isolated H3 equine influenza A virus, as well as methods of preparing and using the virus, and genes or proteins thereof. |
| FILED | Thursday, October 05, 2017 |
| APPL NO | 15/725735 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/70 (20130101) A61K 2039/543 (20130101) A61K 2039/552 (20130101) A61K 2039/5252 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10035841 | Clavijo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alfonso Clavijo (Rio de Janeiro, Brazil); Aida Elizabeth Rieder (Westbrook, Connecticut); Abu Sayed (East Lyme, Connecticut); Mangkey A. Bounpheng (Austin, Texas); Thomas G. Burrage (Guilford, Connecticut); Brooke A. Dancho (Athens, Georgia); Sabena Uddowla Blakeney (Lanham, Maryland) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF HOMELAND SECURITY (Washington, District of Columbia) |
| INVENTOR(S) | Alfonso Clavijo (Rio de Janeiro, Brazil); Aida Elizabeth Rieder (Westbrook, Connecticut); Abu Sayed (East Lyme, Connecticut); Mangkey A. Bounpheng (Austin, Texas); Thomas G. Burrage (Guilford, Connecticut); Brooke A. Dancho (Athens, Georgia); Sabena Uddowla Blakeney (Lanham, Maryland) |
| ABSTRACT | This disclosure pertains to isolated antibodies or antigen binding fragments thereof that specifically bind to the 3ABC non-structural protein of Foot-and-Mouth Disease virus (FMDV), wherein the antibodies or antigen binding fragments thereof recognize the amino acid sequence of SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6 or SEQ ID NO: 12. Accordingly, this disclosure also pertains to polypeptides having an amino acid sequence selected from SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5 or SEQ ID NO: 12. Monoclonal antibody Mab 40C8 is also provided. The current disclosure also pertains to methods of detecting FMDV infection in an animal (including assays differentiating infected animals from vaccinated animals (DIVA)) and kits for performing the detection methods. Competitive ELISA kits comprising the antibody or antigen binding fragment thereof and immunoassay plates coated with the polypeptide comprising the amino acid sequence selected from SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6 and/or SEQ ID NO: 12 are also provided. |
| FILED | Friday, January 29, 2016 |
| APPL NO | 15/010278 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1009 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/32122 (20130101) C12N 2770/32134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10035841 | Clavijo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alfonso Clavijo (Rio de Janeiro, Brazil); Aida Elizabeth Rieder (Westbrook, Connecticut); Abu Sayed (East Lyme, Connecticut); Mangkey A. Bounpheng (Austin, Texas); Thomas G. Burrage (Guilford, Connecticut); Brooke A. Dancho (Athens, Georgia); Sabena Uddowla Blakeney (Lanham, Maryland) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF HOMELAND SECURITY (Washington, District of Columbia) |
| INVENTOR(S) | Alfonso Clavijo (Rio de Janeiro, Brazil); Aida Elizabeth Rieder (Westbrook, Connecticut); Abu Sayed (East Lyme, Connecticut); Mangkey A. Bounpheng (Austin, Texas); Thomas G. Burrage (Guilford, Connecticut); Brooke A. Dancho (Athens, Georgia); Sabena Uddowla Blakeney (Lanham, Maryland) |
| ABSTRACT | This disclosure pertains to isolated antibodies or antigen binding fragments thereof that specifically bind to the 3ABC non-structural protein of Foot-and-Mouth Disease virus (FMDV), wherein the antibodies or antigen binding fragments thereof recognize the amino acid sequence of SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6 or SEQ ID NO: 12. Accordingly, this disclosure also pertains to polypeptides having an amino acid sequence selected from SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5 or SEQ ID NO: 12. Monoclonal antibody Mab 40C8 is also provided. The current disclosure also pertains to methods of detecting FMDV infection in an animal (including assays differentiating infected animals from vaccinated animals (DIVA)) and kits for performing the detection methods. Competitive ELISA kits comprising the antibody or antigen binding fragment thereof and immunoassay plates coated with the polypeptide comprising the amino acid sequence selected from SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6 and/or SEQ ID NO: 12 are also provided. |
| FILED | Friday, January 29, 2016 |
| APPL NO | 15/010278 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1009 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/32122 (20130101) C12N 2770/32134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10038703 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Mingyan Liu (Ann Arbor, Michigan); Michael Bailey (Champaign, Illinois); Manish Karir (Ann Arbor, Michigan); Yang Liu (Ann Arbor, Michigan); Jing Zhang (Ann Arbor, Michigan) |
| ABSTRACT | Embodiments are disclosed for profiling network-level malicious activity. Profiling embodiments include observing malicious activity, representing such activity in accordance with a set of representative features, capturing temporal evolution of this malicious behavior and its dynamics, and using this temporal evolution to reveal key risk related properties of these networks. Embodiments are further disclosed addressing the connectedness of various networks and similarity in network-level maliciousness. Embodiments directed to similarity analyses include focusing on the notion of similarity—a quantitative measure of the extent to which the dynamic evolutions of malicious activities from two networks are alike, and mapping this behavioral similarity to their similarity in certain spatial features, which includes their relative proximity to each other and may be used to help predict the future maliciousness of a particular network. The embodiments described may be applicable to various network aggregation levels. |
| FILED | Thursday, July 16, 2015 |
| APPL NO | 14/801016 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 61/2007 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101) H04L 63/1433 (20130101) H04L 63/1483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Classified Government Agency
| US 10036765 | Dwyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morristown, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Paul W. Dwyer (Seattle, Washington); John Stanley Starzynski (North Bend, Washington) |
| ABSTRACT | In some examples, the disclosure describes an accelerometer having improved hysteresis effects, the accelerometer including a proof mass assembly including a proof mass, a support structure, and a flexure flexibly connecting the proof mass to the support structure to allow the proof mass to move about the plane defined by the support structure. Some examples may include at least one thin film lead including an electrically conductive material on the flexure, where the at least one thin film lead provides an electrical connection between an electrical component on the support structure and an electrical component on the proof mass, and where the at least one thin film lead comprises at least one of a yield strength greater than pure gold or a thermal expansion coefficient less than pure gold. |
| FILED | Friday, July 10, 2015 |
| APPL NO | 14/796945 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/0235 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) G01P 15/125 (20130101) Original (OR) Class G01P 15/132 (20130101) G01P 15/0802 (20130101) G01P 2015/0857 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10036738 | McCord et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce McCord (Miami, Florida); Inge Corbin (Stockbridge, Georgia); Lucas Blanes (Sydney, Australia) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Bruce McCord (Miami, Florida); Inge Corbin (Stockbridge, Georgia); Lucas Blanes (Sydney, Australia) |
| ABSTRACT | Paper microfluidic devices for testing for explosives are provided, along with methods of fabricating and using the same. One or more channels are formed on a paper substrate, and a test spot is formed in at least one of the channels. The channels can be hydrophobic. A test reagent is provided in the test spot and tests for explosives. |
| FILED | Monday, December 04, 2017 |
| APPL NO | 15/830793 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 3/5027 (20130101) B01L 2200/10 (20130101) B01L 2200/12 (20130101) B01L 2300/126 (20130101) B01L 2300/165 (20130101) B01L 2300/0825 (20130101) B01L 2300/0864 (20130101) B01L 2300/0887 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10034638 | Ansari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Sardar Ansari (Richmond, Virginia); Kayvan Najarian (Northville, Michigan); Kevin Ward (Superior Township, Michigan) |
| ABSTRACT | Techniques for motion artifact (MA) reduction in impedance plethysmography (IP) and other physiological signals are provided. The techniques limit the amplitude of MA filtered signals by imposing an “ε-tube.” The techniques may include the introduction of a regularization term to ensure that the pattern of a filtered signal is similar to the pattern of the primary component of the original, unfiltered signal by maximizing the regularity of the filtered signal. The techniques may be integrated into a portable monitoring device, such as an armband, to remove MA from various diagnostic signals and to extract primary signal components for producing enhanced device performance. |
| FILED | Monday, February 22, 2016 |
| APPL NO | 15/049653 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/031 (20130101) A61B 5/0402 (20130101) A61B 5/0535 (20130101) A61B 5/721 (20130101) Original (OR) Class A61B 5/725 (20130101) A61B 5/0836 (20130101) A61B 5/7214 (20130101) A61B 5/7253 (20130101) A61B 8/488 (20130101) A61B 8/5223 (20130101) A61B 8/5269 (20130101) A61B 8/5276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10036631 | Huang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yaxiong Huang (Austin, Texas) |
| ASSIGNEE(S) | Texas Department of Transportation (Austin, Texas) |
| INVENTOR(S) | Yaxiong Huang (Austin, Texas) |
| ABSTRACT | In some embodiments, a system for measuring surface features may include a patter projector, at least one digital imaging device, and an image processing device. The pattern projector may project, during use, a pattern of light on a surface of an object. In some embodiments, the pattern projector moves, during use, the pattern of light along the surface of the object. In some embodiments, the pattern projector moves the pattern of light in response to electronic control signals. At least one of the digital imaging devices may record, during use, at least one image of the projected patter of light. The image processing device which, during use, converts projected patterns of light recorded on at least one of the images to three-dimensional data points representing a surface geometry of the object using relative positions and relative angles between the at least one imaging device and the pattern projector. |
| FILED | Wednesday, May 01, 2013 |
| APPL NO | 13/874968 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/303 (20130101) Original (OR) Class G01B 11/2527 (20130101) G01B 11/2545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10035661 | Bouchard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Austin C. Bouchard (Washington, District of Columbia); Alexander S. Klinger (Silver Spring, Maryland) |
| ABSTRACT | A device, system, and method for detecting a covering sleeve on a container. A sleeve detection system includes a conveyor, a height profile acquisition device, and a processor in communication with the height profile acquisition device. The height profile acquisition device is configured to acquire height profiles of a tray traveling on the conveyor. The processor is configured to analyze height profiles received from the height profile acquisition device to determine a sleeve status of the tray. In some embodiments, a light gate is disposed across the conveyor and configured to detect the presence of a tray on the conveyor approaching the height profile acquisition device. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 15/427956 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 13/00 (20130101) B65G 43/08 (20130101) Original (OR) Class B65G 47/53 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/0608 (20130101) G01B 17/00 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 8/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 31, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180731.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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