FedInvent™ Patents
Patent Details for Tuesday, August 07, 2018
This page was updated on Monday, March 27, 2023 at 05:36 AM GMT
Department of Health and Human Services (HHS)
US 10039285 | Savage et al. |
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FUNDED BY |
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APPLICANT(S) | BRIGHAM YOUNG UNIVERSITY (Provo, Utah) |
ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
INVENTOR(S) | Paul B. Savage (Mapleton, Utah); Carl Genberg (Las Vegas, Nevada) |
ABSTRACT | Particulate ceragenin materials may be manufactured by (i) providing a ceragenin feed material comprised of ceragenin molecules, each having a sterol backbone and a plurality cationic groups attached thereto; (ii) fracturing the ceragenin feed material in a milling apparatus to produce a ceragenin particulate material having a particle size distribution with a median particle size in a range from 5 nm to 20 μm; and (iii) during fracturing, maintaining the ceragenin feed with a moisture content of less than or equal to 10% by weight. |
FILED | Wednesday, March 13, 2013 |
APPL NO | 14/398094 |
ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/12 (20130101) A01N 45/00 (20130101) Original (OR) Class A01N 45/00 (20130101) A01N 55/00 (20130101) A01N 55/08 (20130101) A01N 2300/00 (20130101) Crushing, Pulverising, or Disintegrating in General; Milling Grain B02C 23/12 (20130101) B02C 23/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039445 | Torch |
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FUNDED BY |
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APPLICANT(S) | William C. Torch (Reno, Nevada) |
ASSIGNEE(S) | Google LLC (Mountain View, California) |
INVENTOR(S) | William C. Torch (Reno, Nevada) |
ABSTRACT | Biosensor, communicator, and/or controller apparatus, systems, and methods are provided for monitoring movement of a person's eye. The apparatus includes a device configured to be worn on a user's head, a light source for directing light towards one or both eyes of the user, one or more image guides on the device for viewing one or both eyes of the user, and one or more cameras carried on the device and coupled to the image guides for acquiring images of the eyes and/or the user's surroundings. The apparatus may include a cable and/or a transmitter for transmitting image data from the camera to a remote location, e.g., to processor and/or display for analyzing and/or displaying the image data. A system including the apparatus may be used to monitor one or more oculometric parameters, e.g., pupillary response, and/or to control a computer using the user's eyes instead of a mouse. |
FILED | Wednesday, January 13, 2010 |
APPL NO | 12/687125 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00009 (20130101) A61B 3/0025 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039474 | Taylor et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Russell H. Taylor (Severna Park, Maryland); Marcin Arkadiusz Balicki (Baltimore, Maryland) |
ABSTRACT | An embodiment in accordance with the present invention provides a tracking system architecture for tracking surgical tools in a surgical field. The system architecture is integrated into a mask placed directly on the face of the patient. The system can combine multiple imaging and range finding technologies for tracking the eye and the surgical instrumentation. The system can be used to generate a three dimensional scene for use during the surgical procedure. Additionally, the system can incorporate a modular design to account for variable anatomy. The system described is for eye surgery applications. However, the system could also be used for other procedures such as cochlear implant or craniotomy. |
FILED | Tuesday, January 28, 2014 |
APPL NO | 14/165972 |
ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/061 (20130101) Original (OR) Class A61B 34/20 (20160201) A61B 2034/2055 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039530 | Taylor et al. |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Russell H. Taylor (Severna Park, Maryland); Iulian Iordachita (Lutherville-Timonium, Maryland); Jin U. Kang (Ellicott City, Maryland); Xuan Liu (Baltimore, Maryland) |
ABSTRACT | A surgical tool system according to an embodiment of the current invention includes a surgical tool, and an interferometry system optically coupled to the surgical tool. The surgical tool includes a body section, a sensor section at least one of attached to or integral with the body section, and a surgical section at least one of attached to or integral with the sensor section at an opposing end of the sensor section from the body section. The sensor section comprises an interferometric optical sensor defining a reference distance that changes in response to at least one of a force or a torque when applied to the surgical section of the surgical tool. |
FILED | Friday, December 18, 2015 |
APPL NO | 14/973823 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00 (20130101) Original (OR) Class A61B 17/3478 (20130101) A61B 19/46 (20130101) A61B 19/5244 (20130101) A61B 90/06 (20160201) A61B 2017/00084 (20130101) A61B 2017/305 (20130101) A61B 2017/00986 (20130101) A61B 2019/465 (20130101) A61B 2019/466 (20130101) A61B 2019/5261 (20130101) A61B 2034/2061 (20160201) A61B 2090/064 (20160201) A61B 2090/066 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/007 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039562 | Bailey et al. |
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APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
INVENTOR(S) | Michael Bailey (Seattle, Washington); Bryan Cunitz (Seattle, Washington); Barbrina Dunmire (Burien, Washington) |
ABSTRACT | Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects. |
FILED | Tuesday, March 07, 2017 |
APPL NO | 15/452590 |
ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/7232 (20130101) A61B 6/03 (20130101) A61B 6/485 (20130101) A61B 8/085 (20130101) A61B 8/488 (20130101) A61B 17/225 (20130101) Original (OR) Class A61B 17/2256 (20130101) A61B 2017/22005 (20130101) A61B 2090/378 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 2007/0004 (20130101) A61N 2007/0052 (20130101) A61N 2007/0082 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52071 (20130101) G01S 15/899 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039723 | Roe et al. |
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APPLICANT(S) | DeviceFarm Inc. (Newark, California) |
ASSIGNEE(S) | DeviceFarm, Inc. (Newark, California) |
INVENTOR(S) | Jeffrey N Roe (Pleasanton, California); Timothy C Grammer (Pleasant Hill, California); Raul Ignacio Barrera-Barraza (Fremont, California); Eric Tridas (St. Petersburg, Florida) |
ABSTRACT | A system and method includes delivery of a redox gas solution to treat onychomycosis, wherein the redox gas solution comprises a reactive species dissolved in a perfluorocarbon liquid, and wherein the reactive species may include, alone or in combination, one or more of reactive oxygen, reactive nitrogen, reactive chlorine, or reactive bromine species, and the perfluorocarbon liquid may include perfluorodecalin. |
FILED | Tuesday, March 21, 2017 |
APPL NO | 15/464761 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/025 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/44 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039741 | Zheng et al. |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Wei Zheng (Potomac, Maryland); Juan Jose Marugan (Gaithersburg, Maryland); Ke Liu (Cambridge, Maryland); Noel Terrence Southall (Chevy Chase, Maryland); Christopher P. Austin (Potomac, Maryland) |
ABSTRACT | This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of δ tocopherol in the treatment of diseases and conditions related to lysosomal storage disorders. Included in the present disclosure is a method for the modulation of cholesterol recycling. Further, the disclosure relates to conditions such as Niemann-Pick type C disease, Farber disease, Niemann-Pick type A disease, Wolman disease and Tay Sachs disease. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of δ tocopherol. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of δ tocopherol in combination with cyclodextrin to a patient in need thereof. |
FILED | Wednesday, August 17, 2016 |
APPL NO | 15/239753 |
ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/36 (20130101) A61K 31/355 (20130101) Original (OR) Class A61K 31/355 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/724 (20130101) A61K 31/724 (20130101) A61K 36/185 (20130101) A61K 36/185 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039751 | Penny et al. |
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FUNDED BY |
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APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Hweixian Leong Penny (Singapore, Singapore); Edgar George Engleman (Atherton, California); Nupur Bhattacharya (Palo Alto, California) |
ABSTRACT | An agent that increases local concentration of retinoic acid (RA) in the intestine through modifying enzymatic pathways involved in RA metabolism is administered in a dose effective to inhibit or reverse production of inflammatory mediators by intestinal dendritic cells and thereby reduce intestinal inflammation and tumor growth associated with intestinal inflammation. |
FILED | Monday, March 20, 2017 |
APPL NO | 15/464010 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 31/4184 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039756 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Gong Chen (State College, Pennsylvania); Zheng Wu (State College, Pennsylvania); Ziyuan Guo (State College, Pennsylvania) |
ABSTRACT | The disclosure relates to methods and compositions for reducing memory loss. Specifically, methods of using inhibitors of GAT-3 polypeptide activity to reduce memory loss in mammals suffering from Alzheimer's disease (AD) are provided. Further provided are methods for identifying a mammal as having AD by detecting the presence of an elevated level of gamma-aminobutyric acid (GABA) within a mammal's brain. |
FILED | Tuesday, July 15, 2014 |
APPL NO | 14/901620 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/445 (20130101) A61K 31/445 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/455 (20130101) Original (OR) Class A61K 31/551 (20130101) A61K 31/551 (20130101) A61K 31/5517 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 51/0402 (20130101) A61K 51/0406 (20130101) A61K 51/1018 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/9426 (20130101) G01N 2800/2821 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039764 | Piazza |
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FUNDED BY |
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APPLICANT(S) | University of South Alabama (Mobile, Alabama) |
ASSIGNEE(S) | University of South Alabama (Mobile, Alabama) |
INVENTOR(S) | Gary A. Piazza (Daphne, Alabama) |
ABSTRACT | Disclosed are methods for treating cancer and precancerous conditions with PDE10A specific inhibitors and diagnosis of neoplastic diseases based on elevated levels of PDE10A. |
FILED | Friday, July 11, 2014 |
APPL NO | 14/904632 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) A61K 31/472 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/4155 (20130101) A61K 31/4409 (20130101) A61K 31/4709 (20130101) A61K 31/4745 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57496 (20130101) G01N 2333/916 (20130101) G01N 2800/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039772 | Sanna |
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APPLICANT(S) | Pietro Paolo Sanna (San Diego, California) |
ASSIGNEE(S) | |
INVENTOR(S) | Pietro Paolo Sanna (San Diego, California) |
ABSTRACT | Disclosed are methods and compositions for treating alcohol dependence by administration to a patient of an inhibitor of 11β-hydroxysteroid dehydrogenases (11β-HSD) to modulate glucocorticoid effects. One such compound is the 11β-HSD inhibitor carbenoxolone (18β-glycyrrhetinic acid 3β-O-hemisuccinate), which has been extensively employed in the clinic for the treatment of gastritis and peptic ulcer. Carbenoxolone is active on both 11β-HSD1 and 2 isoforms. Here, carbenoxolone is surprisingly shown to reduce both baseline and excessive drinking in rats and mice. The carbenoxolone diastereomer 18α-glycyrrhetinic acid 3β-O-hemisuccinate (αCBX), which the applicants discovered to be selective for 11β-HSD2, was also effective in reducing alcohol drinking in mice. Thus, 11β-HSD inhibitors are a new class of candidate alcohol abuse medications and existing 11β-HSD inhibitor drugs may be re-purposed for alcohol abuse treatment. |
FILED | Saturday, November 12, 2016 |
APPL NO | 15/350052 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/56 (20130101) A61K 31/58 (20130101) A61K 31/585 (20130101) Original (OR) Class A61K 31/4965 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039782 | Roe et al. |
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FUNDED BY |
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APPLICANT(S) | DeviceFarm Inc. (Newark, California) |
ASSIGNEE(S) | DeviceFarm, Inc. (Newark, California) |
INVENTOR(S) | Jeffrey N Roe (San Ramon, California); Timothy C Grammer (Pleasant Hill, California); Michael P O'Neil (Dublin, California) |
ABSTRACT | A system and method includes delivery of a redox gas solution to treat onychomycosis, wherein the redox gas solution comprises a reactive species dissolved in a perfluorocarbon liquid, and wherein the reactive species may include, alone or in combination, one or more of reactive oxygen, reactive nitrogen, reactive chlorine, or reactive bromine species, and the perfluorocarbon liquid may include perfluorodecalin. |
FILED | Wednesday, December 09, 2015 |
APPL NO | 14/963552 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/02 (20130101) A61K 31/02 (20130101) A61K 33/00 (20130101) A61K 33/00 (20130101) A61K 33/04 (20130101) Original (OR) Class A61K 33/04 (20130101) A61K 33/20 (20130101) A61K 33/20 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039785 | Tan et al. |
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APPLICANT(S) | Jun Tan (Tampa, Florida); Paul R. Sanberg (Spring Hill, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Jun Tan (Tampa, Florida); Paul R. Sanberg (Spring Hill, Florida) |
ABSTRACT | Administration of human umbilical cord blood cells (HUCBC) or HUCBC-derived plasma is used to treat amyloid-based diseases, such as Alzheimer's disease, Huntington's disease, cerebral amyloid antigopathy, and type-II diabetes. Modulating inflammatory reactions by infusing HUCBC resulted in a marked reduction of amyloid plaques and immune-associated cellular damage. HUCBC infusion also significantly reduced cerebral amyloid angiopathy in mice models. These effects were associated with suppression of the CD40-CD40L interaction and a reduction in surface expressed CD-40 was observed on immune cells. Further, Aβ phagocytic activity was increased and soluble and insoluble Aβ protein levels were modulated by treatment. HUCBC-infused sera also significantly increased phagocytosis of Aβ1-42 peptide and inhibited immune cell CD40 expression and reduced cerebral amyloid angiopathy. |
FILED | Tuesday, June 28, 2016 |
APPL NO | 15/195243 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Original (OR) Class A61K 35/44 (20130101) A61K 2035/122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039796 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Houston System (Houston, Texas) |
ASSIGNEE(S) | The University of Houston System (Houston, Texas) |
INVENTOR(S) | Xiaoliu Zhang (Houston, Texas); Xinping Fu (Houston, Texas) |
ABSTRACT | The present invention is directed to the composition and use of a modified Herpes Simplex Virus Type 2 (HSV-2) as a medicament in the treatment of cancer. The modified HSV-2 has fusogenic activity, and comprises a modified/mutated ICP10 polynucleotide encoding a polypeptide having ribonucleotide reductase activity and lacking protein kinase activity. |
FILED | Friday, February 13, 2015 |
APPL NO | 14/622263 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/763 (20130101) Original (OR) Class A61K 35/763 (20130101) A61K 38/00 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 39/245 (20130101) A61K 2039/572 (20130101) A61K 2039/585 (20130101) A61K 2039/5256 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/16622 (20130101) C12N 2710/16632 (20130101) C12N 2710/16643 (20130101) C12N 2710/16671 (20130101) C12N 2810/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039807 | Maynard et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Heather D. Maynard (Los Angeles, California); Thi Nguyen (Reseda, California) |
ABSTRACT | A heparin mimicking polymer, its conjugate with bFGF, and method of making and using the same are disclosed. In particular, described herein are conjugates of biologic agents (e.g., bFGF) and heparin mimicking polymers having superior stability while retaining full native activity after a variety of stressors. |
FILED | Wednesday, February 08, 2017 |
APPL NO | 15/427918 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/78 (20130101) A61K 31/795 (20130101) A61K 38/1825 (20130101) Original (OR) Class A61K 47/32 (20130101) Peptides C07K 14/503 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/14 (20130101) C08F 220/28 (20130101) C08F 2220/286 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039813 | Goosens |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Ki Ann Goosens (Cambridge, Massachusetts) |
ABSTRACT | The invention relates to methods of protecting against chronic stress in a subject and treating stress sensitive disorders in a subject by antagonizing ghrelin or ghrelin receptor. |
FILED | Thursday, February 07, 2013 |
APPL NO | 14/377229 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1796 (20130101) A61K 39/00 (20130101) A61K 39/0005 (20130101) Original (OR) Class A61K 45/00 (20130101) A61K 2039/545 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 2333/60 (20130101) G01N 2800/7004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039816 | Nolan et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Elizabeth Marie Nolan (Cambridge, Massachusetts); Phoom Chairatana (Cambridge, Massachusetts); Manuela Raffatellu (Irvine, California); Martina Sassone Corsi (Irvine, California); Araceli Perez-Lopez (Irvine, California) |
ABSTRACT | The present invention provides novel enterobactin-carrier protein conjugates and salmochelin-carrier protein conjugates, such as compounds of Formula (I), and salts thereof. The present invention also provides compositions, kits, and methods that involve the compounds of Formula (I) and are useful in inducing an immune response, treating a bacterial infection and/or inflammatory bowel disease in a subject, preventing a bacterial infection and/or inflammatory bowel disease in a subject, or inhibiting the growth of or killing a bacterium. |
FILED | Thursday, April 30, 2015 |
APPL NO | 14/700397 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0013 (20130101) A61K 39/025 (20130101) Original (OR) Class A61K 47/646 (20170801) A61K 47/6415 (20170801) A61K 2039/627 (20130101) A61K 2039/6037 (20130101) Peptides C07K 19/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56916 (20130101) G01N 2333/245 (20130101) G01N 2333/255 (20130101) G01N 2469/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039820 | Coller et al. |
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FUNDED BY |
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APPLICANT(S) | HAWAII BIOTECH, INC. (Honolulu, Hawaii) |
ASSIGNEE(S) | Hawaii Biotech, Inc. (Honolulu, Hawaii) |
INVENTOR(S) | Beth-Ann Coller (West Point, Pennsylvania); Vidya Pai (Bethesda, Maryland); Carolyn L. Weeks-Levy (Honolulu, Hawaii); Steven A. Ogata (Kailua, Hawaii) |
ABSTRACT | A West Nile virus vaccine for human use is described that preferably contains a recombinantly produced form of truncated West Nile virus envelope glycoprotein and aluminum adjuvant. The vaccine is acceptable for use in the general population, including immunosuppressed, immunocompromised, and immunosenescent individuals. The vaccine is safe and effective for use in all healthy and at-risk populations. A pharmaceutically acceptable vehicle may also be included in the vaccine. |
FILED | Friday, October 21, 2016 |
APPL NO | 15/331596 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/55505 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/24134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039825 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
INVENTOR(S) | Hyung Kim (Los Angeles, California); Yanping Wang (Los Angeles, California) |
ABSTRACT | The invention provides methods for treating a malignant neoplastic cell proliferative disorder or disease, comprising administering to a subject in need thereof an effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent. Such methods find utility in the treatment of certain subsets of malignant neoplastic cell proliferative disorders or diseases, e.g. renal cell carcinoma and melanoma. The invention also provides for pharmaceutical compositions comprising a therapeutically effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent in a pharmaceutically acceptable carrier. |
FILED | Monday, July 25, 2016 |
APPL NO | 15/218464 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/2812 (20130101) C07K 2317/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039838 | Komatsu et al. |
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FUNDED BY |
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APPLICANT(S) | Vascular BioSciences (San Diego, California); Sanford-Burnham Medical Research Institute (La Jolla, California) |
ASSIGNEE(S) | Vascular Biosciences (San Diego, California); Sanford-Burnham Medical Research Institute (La Jolla, California) |
INVENTOR(S) | Masanobu Komatsu (La Jolla, California); David Mann (San Diego, California); Erkki Ruoslahti (La Jolla, California) |
ABSTRACT | Disclosed are compositions and methods useful for delivering targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to effect a beneficial therapeutic result. The disclosed targeting is useful for delivering therapeutic and detectable agents to diseased tissue in an animal. |
FILED | Tuesday, November 10, 2015 |
APPL NO | 14/936969 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/551 (20130101) A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) A61K 47/64 (20170801) A61K 47/48246 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039844 | Witney et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Timothy Witney (Denton, United Kingdom); Michelle L. James (Menlo Park, California); Sanjiv S. Gambhir (Portola Valley, California) |
ABSTRACT | A novel pyruvate kinase M2 (PKM2)-specific activator, [11C]DASA-23 and derivatives thereof, and methods for their rapid synthesis are provided. The probes are particularly useful in methods for the non-invasive positron emission tomography (PET) detection and imaging of PKM2 expression in subcutaneous and orthotopic tumors. [11C]DASA-23 cell uptake correlates with PKM2 protein expression in cultured tumor cells and orthotopic tumors are delineated from the surrounding normal brain tissue in vivo. |
FILED | Wednesday, December 02, 2015 |
APPL NO | 14/956431 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0459 (20130101) Original (OR) Class Heterocyclic Compounds C07D 295/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/57496 (20130101) G01N 2333/91215 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039847 | Bradbury et al. |
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FUNDED BY |
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APPLICANT(S) | Sloan-Kettering Institute for Cancer Research (New York, New York); Cornell University (Ithaca, New York); The Curators of the University of Missouri (Columbia, Missouri) |
ASSIGNEE(S) | |
INVENTOR(S) | Michelle S. Bradbury (New York, New York); Ulrich Wiesner (Ithaca, New York); Oula Penate Medina (Kiel, Germany); Andrew Burns (Niskayuna, New York); Jason S. Lewis (New York, New York); Steven M. Larson (New York, New York); Thomas P. Quinn (Columbia, Missouri) |
ABSTRACT | The present invention provides a fluorescent silica-based nanoparticle that allows for precise detection, characterization, monitoring and treatment of a disease such as cancer. The nanoparticle has a range of diameters including between about 0.1 nm and about 100 nm, between about 0.5 nm and about 50 nm, between about 1 nm and about 25 nm, between about 1 nm and about 15 nm, or between about 1 nm and about 8 nm. The nanoparticle has a fluorescent compound positioned within the nanoparticle, and has greater brightness and fluorescent quantum yield than the free fluorescent compound. The nanoparticle also exhibits high biostability and biocompatibility. To facilitate efficient urinary excretion of the nanoparticle, it may be coated with an organic polymer, such as poly(ethylene glycol) (PEG). The small size of the nanoparticle, the silica base and the organic polymer coating minimizes the toxicity of the nanoparticle when administered in vivo. In order to target a specific cell type, the nanoparticle may further be conjugated to a ligand, which is capable of binding to a cellular component associated with the specific cell type, such as a tumor marker. In one embodiment, a therapeutic agent may be attached to the nanoparticle. To permit the nanoparticle to be detectable by not only optical fluorescence imaging, but also other imaging techniques, such as positron emission tomography (PET), single photon emission computed tomography (SPECT), computerized tomography (CT), bioluminescence imaging, and magnetic resonance imaging (MRI), radionuclides/radiometals or paramagnetic ions may be conjugated to the nanoparticle. |
FILED | Monday, September 25, 2017 |
APPL NO | 15/714189 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/0093 (20130101) A61K 51/1244 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/552 (20130101) G01N 33/574 (20130101) G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 33/54346 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039860 | Schmuck et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Eric G. Schmuck (Deforest, Wisconsin); Kurt W. Saupe (Madison, Wisconsin) |
ABSTRACT | A bioscaffold made from an isolated cardiac fibroblast-derived 3-dimensional extracellular matrix (ECM) is disclosed. The bioscaffold can be used as an epicardial patch for the delivery of therapeutic cells into myocardial tissue. Methods of making the 3-dimensional extracellular matrix using cultured cardiac fibroblasts are also disclosed. |
FILED | Friday, April 08, 2016 |
APPL NO | 15/094619 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/28 (20130101) A61K 35/33 (20130101) A61K 35/33 (20130101) A61K 35/34 (20130101) A61K 38/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/3633 (20130101) Original (OR) Class A61L 27/3687 (20130101) A61L 27/3834 (20130101) A61L 2300/414 (20130101) A61L 2430/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 5/0663 (20130101) C12N 2513/00 (20130101) C12N 2533/90 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039917 | Kilgore et al. |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Kevin Kilgore (Avon Lake, Ohio); Douglas Michael Ackermann, Jr. (Palo Alto, California); Niloy Bhadra (Cleveland Heights, Ohio); Narendra Bhadra (Chesterland, Ohio); Joe Payer (Brecksville, Ohio) |
ABSTRACT | Example adjustable electrodes are described. One example adjustable electrode includes two or more contacts configured to selectively deliver high frequency alternating current (HFAC) to a nerve in an amount sufficient to produce an HFAC nerve conduction block in the nerve. The example adjustable electrode may also include a logic configured to selectively control which of the two or more contacts deliver HFAC to the nerve to control whether the nerve electrode is in a first (e.g., onset response mitigating) configuration or in a second (e.g., HFAC nerve conduction block maintenance) configuration. The electrode may be used in applications including, but not limited to, nerve block applications, and nerve stimulation applications. The electrode may be adjusted by changing attributes including, but not limited to, the number, length, orientation, distance between, surface area, and distance from a nerve of contacts to be used to deliver the HFAC. |
FILED | Friday, April 29, 2016 |
APPL NO | 15/142114 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/0556 (20130101) Original (OR) Class A61N 1/36071 (20130101) A61N 1/36185 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039921 | Nirenberg |
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FUNDED BY |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Sheila Nirenberg (New York, New York) |
ABSTRACT | The invention provides a retinal prosthetic method and device that mimics the responses of the retina to a broad range of stimuli, including natural stimuli. Ganglion cell firing patterns are generated in response to a stimulus using a set of encoders, interfaces, and transducers, where each transducer targets a single cell or a small number of cells. The conversion occurs on the same time scale as that carried out by the normal retina. In addition, aspects of the invention may be used with robotic or other mechanical devices, where processing of visual information is required. The encoders may be adjusted over time with aging or the progression of a disease. |
FILED | Monday, December 28, 2015 |
APPL NO | 14/981242 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/08 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/36046 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040047 | Craighead et al. |
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FUNDED BY |
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APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Harold Craighead (Ithaca, New York); Christine Tan (Singapore, Singapore) |
ABSTRACT | The present invention relates to a device for isolating and recovering a biomolecule from a test sample. The device includes a support and at least one peelable layer deposited on at least a portion of the support. The peelable layer includes a substrate having a target component immobilized on the substrate. The device is effective for isolating and recovering a biomolecule having affinity to the target component. The present invention also relates to systems and methods of using the device. The present invention also relates to a biomolecule elution strip and related methods. |
FILED | Wednesday, June 10, 2015 |
APPL NO | 14/735874 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00585 (20130101) B01J 2219/00596 (20130101) B01J 2219/00722 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1048 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) G01N 33/54386 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040062 | Beebe et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Ben P. Casavant (Madison, Wisconsin); David J. Guckenberger (Oconomowoc, Wisconsin); Scott M. Berry (Madison, Wisconsin) |
ABSTRACT | A device and method are proved for transferring a target from a first location to a second location. The target is bound to solid phase substrate to form a target bound solid phase substrate. The device includes transfer surface for receiving the target bound solid phase substrate thereon for transfer. The transfer surface movable between a first position wherein the transfer surface is aligned with the first location and spaced therefrom by a distance and a second position wherein the transfer surface is aligned with the second location. An alignment structure aligns the transfer surface with respect to the second location, with the transfer surface in the second position. A force is movable between an attraction position wherein the target bound solid phase substrate are drawn toward the transfer surface and a discharge position wherein the target bound solid phase substrate are free of the force. |
FILED | Tuesday, January 14, 2014 |
APPL NO | 14/154695 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/563 (20130101) B01L 3/5088 (20130101) B01L 3/50825 (20130101) B01L 2200/025 (20130101) B01L 2200/0657 (20130101) B01L 2200/0668 (20130101) B01L 2300/042 (20130101) B01L 2400/021 (20130101) B01L 2400/043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040146 | Squier et al. |
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FUNDED BY |
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APPLICANT(S) | Colorado School of Mines (Golden, Colorado) |
ASSIGNEE(S) | COLORADO SCHOOL OF MINES (Golden, Colorado) |
INVENTOR(S) | Jeff A. Squier (Golden, Colorado); Erica K. Block (Golden, Colorado) |
ABSTRACT | A multipass chirped pulse amplification system outfitted with a single-grating, simultaneous spatial and temporal focusing (SSTF) compressor platform is provided. Such a system provides the ability to vary the beam aspect ratio of an SSTF beam, and thus the degree of pulse-front tilt at a focus, while maintaining a net zero-dispersion system. The optical system may include a first optical element or set of optical elements that receives and then varies a pulse-front tilt of a light beam, and a second optical element or set of optical elements that focuses the light beam having the varied pulse-front tilt that is output by the first optical element or set of optical elements. The first optical element or set of optical elements includes an optical grating, two dihedrals, and a retroflector roof mirror. |
FILED | Monday, December 14, 2015 |
APPL NO | 14/968633 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/362 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/00 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) H01S 3/2325 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040682 | Afzali-Ardakani et al. |
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FUNDED BY |
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APPLICANT(S) | Ali Afzali-Ardakani (Ossinging, New York); Stefan Harrer (Yorktown Heights, New York); Binquan Luan (Pleasantville, New York); Hongbo Peng (Chappaqua, New York); Gustavo A. Stolovitzky (Riverdale, New York); Deqiang Wang (Ossining, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Ali Afzali-Ardakani (Ossinging, New York); Stefan Harrer (Yorktown Heights, New York); Binquan Luan (Pleasantville, New York); Hongbo Peng (Chappaqua, New York); Gustavo A. Stolovitzky (Riverdale, New York); Deqiang Wang (Ossining, New York) |
ABSTRACT | A technique for a nanodevice is provided. The nanodevice includes a fluidic cell, and a membrane dividing the fluidic cell. A nanopore is formed through the membrane, and the nanopore is coated with an organic compound. A first part of the organic compound binds to a surface of the nanopore and a second part of the organic compound is exposed freely inside of the nanopore. The second part of the organic compound is configured to be switched among a first neutral hydrophilic end group, a second negatively charged hydrophilic end group, and a third neutral hydrophobic end group based on a switching mechanism. |
FILED | Monday, May 07, 2012 |
APPL NO | 13/465280 |
ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Original (OR) Class B82Y 30/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/8593 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040783 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | Emory University (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Jianxiong Jiang (Decatur, Georgia); Thota Ganesh (Alpharetta, Georgia); Yuhong Du (Atlanta, Georgia); Pahk Thepchatri (Atlanta, Georgia); Yi Quan (Decatur, Georgia); Ray J. Dingledine (Atlanta, Georgia) |
ABSTRACT | The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing conditions and diseases in which EP2 receptor activation has a physiological role, such as but not limited to, brain injury, inflammatory diseases, neuroinflammation after a seizure, pain, endometriosis, cancer, rheumatoid arthritis, skin inflammation, vascular inflammation, colitis, and neurological disorders by administering a pharmaceutical composition comprising a compound disclosed herein to a subject in need thereof. |
FILED | Wednesday, November 30, 2016 |
APPL NO | 15/365850 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/4184 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 235/08 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040784 | Stoltz et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Brian M. Stoltz (San Marino, California); Masaki Hayashi (Kanagawa, Japan); Satoshi Hashimoto (Tokyo, Japan) |
ABSTRACT | This disclosure provides methods for intermolecular enantioselective C-acylation of lactams with quaternary stereogenic centers by applying a chiral Ni catalyst. The methods comprise treating a lactam with a chiral Ni catalyst, an aryl nitrile, and an aryl halide. |
FILED | Thursday, March 09, 2017 |
APPL NO | 15/454198 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 207/27 (20130101) C07D 207/273 (20130101) C07D 207/277 (20130101) C07D 409/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040821 | Tseng et al. |
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FUNDED BY |
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APPLICANT(S) | TISSUETECH, INC. (Doral, Florida) |
ASSIGNEE(S) | TISSUETECH, INC. (Miami, Florida) |
INVENTOR(S) | Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Sean Tighe (Fort Lauderdale, Florida); Suzhen Zhang (Miami, Florida); Ying-Tieng Zhu (Homestead, Florida) |
ABSTRACT | Provided herein are methods for the production of native and reconstituted hyaluronan (HA) complexes containing pentraxin-3 (PTX3) and heavy chain 1 (HC1) of inter alpha inhibitor (IαI). Compositions containing the complexes and therapeutic methods using the complexes are provided. Combinations and kits for use in practicing the methods also are provided. |
FILED | Wednesday, July 10, 2013 |
APPL NO | 14/414047 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/191 (20130101) A61K 47/481 (20130101) A61K 47/48992 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2300/41 (20130101) A61L 2300/236 (20130101) A61L 2300/252 (20130101) A61L 2300/412 (20130101) A61L 2300/426 (20130101) Peptides C07K 1/36 (20130101) Original (OR) Class C07K 14/47 (20130101) C07K 14/81 (20130101) C07K 14/525 (20130101) C07K 19/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040822 | Goebel et al. |
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FUNDED BY |
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APPLICANT(S) | Brown University (Providence, Rhode Island); Wayne State University (Detroit, Michigan) |
ASSIGNEE(S) | National Institutes of Health, U.S. Dept. of Health and Human Services, NIH Division of Extramural Inventions and Technology Resources (Bethesda, Maryland) |
INVENTOR(S) | Dennis J. Goebel (Wixom, Michigan); John Marshall (Barrington, Rhode Island) |
ABSTRACT | A therapeutic composition for treating brain injury comprising a polyarginine peptide of from 5 to 9 arginines (SEQ ID NO: 1), and further comprising 1 or more terminal cysteines. The composition is administered in therapeutically effective dosages prophylactically or as soon as possible post-injury in treating neuronal injury. |
FILED | Thursday, December 29, 2016 |
APPL NO | 15/393720 |
ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/00 (20130101) A61K 38/08 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040825 | Chan et al. |
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FUNDED BY |
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APPLICANT(S) | Yee-peng Chan (Bethesda, Maryland); Christopher Broder (Silver Spring, Maryland) |
ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
INVENTOR(S) | Yee-peng Chan (Bethesda, Maryland); Christopher Broder (Silver Spring, Maryland) |
ABSTRACT | This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses. |
FILED | Friday, December 19, 2008 |
APPL NO | 12/808930 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/505 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/18222 (20130101) C12N 2760/18234 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040826 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Jerome Kim (Fort Detrick, Maryland); Stephen Harrison (Boston, Massachusetts); Barton F. Haynes (Durham, North Carolina); Georgia D. Tomaras (Durham, North Carolina); Nelson Michael (Fort Detrick, Maryland) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Jerome Kim (Fort Detrick, Maryland); Stephen Harrison (Boston, Massachusetts); Barton F. Haynes (Durham, North Carolina); Georgia D. Tomaras (Durham, North Carolina); Nelson Michael (Fort Detrick, Maryland) |
ABSTRACT | The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same. |
FILED | Thursday, July 05, 2012 |
APPL NO | 14/130338 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/6075 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/55 (20130101) C07K 2317/92 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16622 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040830 | Chatterjee et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Deb Chatterjee (Potomac, Maryland); Stanislaw Jan Kaczmarczyk (Frederick, Maryland) |
ABSTRACT | The present invention provides methods and compositions for protein delivery. The invention features virus like particles, methods of making virus like particles and methods of using virus like particles to deliver proteins to a cell, to provide protein therapy and to treat diseases or disorders. The invention also features methods of targeting a protein to a cell, methods of protein therapy and methods of treating diseases or disorders using a TUS protein, a NLS or NES identified from full length TUS. |
FILED | Monday, March 28, 2016 |
APPL NO | 15/082401 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6901 (20170801) Peptides C07K 14/00 (20130101) C07K 14/005 (20130101) Original (OR) Class C07K 14/245 (20130101) C07K 2319/09 (20130101) C07K 2319/10 (20130101) C07K 2319/50 (20130101) C07K 2319/705 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/13043 (20130101) C12N 2760/20222 (20130101) C12N 2760/20223 (20130101) C12N 2810/6072 (20130101) C12N 2810/6081 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040834 | Omenetto et al. |
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FUNDED BY |
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APPLICANT(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
ASSIGNEE(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
INVENTOR(S) | Fiorenzo Omenetto (Lexington, Massachusetts); David L. Kaplan (Concord, Massachusetts); Brian Lawrence (New York, New York); Mark Cronin-Golomb (Reading, Massachusetts) |
ABSTRACT | A method of manufacturing a biopolymer optofluidic device including providing a biopolymer, processing the biopolymer to yield a biopolymer matrix solution, providing a substrate, casting the biopolymer matrix solution on the substrate, embedding a channel mold in the biopolymer matrix solution, drying the biopolymer matrix solution to solidify biopolymer optofluidic device, and extracting the embedded channel mold to provide a fluidic channel in the solidified biopolymer optofluidic device. In accordance with another aspect, an optofluidic device is provided that is made of a biopolymer and that has a channel therein for conveying fluid. |
FILED | Monday, January 13, 2014 |
APPL NO | 14/154134 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) B29D 11/00663 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2211/04 (20130101) D10B 2401/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) G01N 33/5436 (20130101) G01N 33/54373 (20130101) G01N 33/54386 (20130101) G01N 2333/43578 (20130101) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 1/005 (20130101) G02B 1/06 (20130101) G02B 1/041 (20130101) G02B 1/045 (20130101) G02B 1/046 (20130101) G02B 5/18 (20130101) G02B 6/138 (20130101) G02B 2006/1213 (20130101) G02B 2006/12102 (20130101) G02B 2006/12104 (20130101) G02B 2006/12107 (20130101) G02B 2006/12171 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040835 | Luo |
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FUNDED BY |
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APPLICANT(S) | Wellstat Ophthalmics Corporation (Gaithersburg, Maryland) |
ASSIGNEE(S) | Wellstat Ophthalmics Corporation (Rockville, Maryland) |
INVENTOR(S) | Tianci Luo (Clarksville, Maryland) |
ABSTRACT | The present invention relates to nucleic acids coding for and capable of expressing a rod-derived cone viability factor (RdCVF) and viral vectors containing these nucleic acids. The invention also relates to compositions and pharmaceutical preparations comprising these nucleic acids or vectors, methods of producing or secreting an RdCVF, and methods of treatment. |
FILED | Tuesday, December 08, 2015 |
APPL NO | 14/962337 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/44 (20130101) A61K 48/0066 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0051 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2799/025 (20130101) C12N 2800/22 (20130101) C12N 2830/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040840 | Antipov et al. |
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FUNDED BY |
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APPLICANT(S) | Silver Creek Pharmaceuticals, Inc. (San Francisco, California) |
ASSIGNEE(S) | Silver Creek Pharmaceuticals, Inc. (San Francisco, California) |
INVENTOR(S) | Laura D. J. Antipov (Oakland, California); Shawdee Eshghi (Oakland, California); Kristopher M. Kuchenbecker (Los Angeles, California); Bjorn L. Millard (Orinda, California); Matthew D. Onsum (El Cerrito, California); Andrea D. Nickerson (San Francisco, California); Timothy R. Stowe (San Francisco, California); Yan Zhang (San Francisco, California) |
ABSTRACT | Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. |
FILED | Friday, September 30, 2016 |
APPL NO | 15/281795 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/65 (20130101) Original (OR) Class C07K 14/765 (20130101) C07K 2319/33 (20130101) C07K 2319/035 (20130101) C07K 2319/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040846 | Frigault et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Matthew J. Frigault (Philadelphia, Pennsylvania); Yangbing Zhao (Cherry Hill, New Jersey); John Scholler (Narberth, Pennsylvania); Carl H. June (Merion Station, Pennsylvania) |
ABSTRACT | The present invention provides compositions and methods for generating a genetically modified T cells comprising a chimeric antigen receptor (CAR) having an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain, wherein the T cell exhibits prolonged exponential expansion in culture that is ligand independent and independent of the addition of exogenous cytokines or feeder cells. |
FILED | Friday, February 22, 2013 |
APPL NO | 14/375015 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040853 | Spies et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas Spies (Seattle, Washington); Veronika Spies (Seattle, Washington) |
ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
INVENTOR(S) | Thomas Spies (Seattle, Washington); Veronika Spies (Seattle, Washington) |
ABSTRACT | Embodiments methods and compositions involving inhibitors of the immunoreceptor Natural Killer Group 2, Member D, (NKG2D) for inhibiting tumor progression and treating cancer. |
FILED | Friday, September 07, 2012 |
APPL NO | 14/343543 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 38/17 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2815 (20130101) Original (OR) Class C07K 16/2833 (20130101) C07K 16/2851 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2330/51 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040856 | Ruiz-Opazo et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | Nelson Ruiz-Opazo (Westwood, Massachusetts); Victoria L. M. Herrera (Westwood, Massachusetts) |
ABSTRACT | Provided herein are novel compositions comprising anti-DEspR antibodies and fragments thereof, including fully human, composite engineered human, humanized, monoclonal, and polyclonal anto-DEspR antibodies and fragments thereof, and methods of their use in a variety of therapeutic applications. The compositions comprising the anti-DEspR antibodies and fragments thereof described herein are useful in diagnostic and imaging methods, such as DEspR-targeted molecular imaging of angiogenesis, and for companion diagnostic and/or in vivo-non invasive imaging and/or assessments. |
FILED | Thursday, June 04, 2015 |
APPL NO | 14/730972 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) A61K 47/481 (20130101) A61K 49/221 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0092 (20130101) Peptides C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 16/2869 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57496 (20130101) G01N 2800/7028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040859 | Behrens et al. |
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FUNDED BY |
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APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania); Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Edward M. Behrens (West Chester, Pennsylvania); Julia E. Rood (Philadelphia, Pennsylvania); Taku Kambayashi (Malvern, Pennsylvania) |
ABSTRACT | Compositions and methods for treating a cytokine release syndrome such as chimeric antigen receptor T-cell cytokine release syndrome or hemophagocytic lymphohistiocytosis are provided. |
FILED | Tuesday, April 21, 2015 |
APPL NO | 15/305272 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1793 (20130101) A61K 39/3955 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/54 (20130101) C07K 14/7155 (20130101) C07K 16/2866 (20130101) Original (OR) Class C07K 2317/72 (20130101) C07K 2317/76 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040865 | Scheinberg et al. |
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FUNDED BY |
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APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York); EUREKA THERAPEUTICS, INC. (Emeryville, California) |
ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Eureka Therapeutics, Inc. (Emeryville, California) |
INVENTOR(S) | David Scheinberg (New York, New York); Tao Dao (New York, New York); Cheng Liu (Oakland, California); Su Yan (State College, Pennsylvania) |
ABSTRACT | The present invention provides antigen binding proteins that specifically bind to Wilms' tumor protein (WT1), including humanized, chimeric and fully human antibodies against WT1, antibody fragments, chimeric antigen receptors (CARs), fusion proteins, and conjugates thereof. The antigen binding proteins and antibodies bind to HLA-A0201-restricted WT1 peptide. Such antibodies, fragments, fusion proteins and conjugates thereof are useful for the treatment of WT1 associated cancers, including for example, breast cancer, ovarian cancer, prostate cancer, chronic myelocytic leukemia, multiple myeloma, acute lymphoblastic leukemia (ALL), acute myeloid/myelogenous leukemia (AML) and myelodysplastic syndrome (MDS). In more particular embodiments, the anti-WT1/A antibodies may comprise one or more framework region amino acid substitutions designed to improve protein stability, antibody binding and/or expression levels. |
FILED | Wednesday, November 30, 2016 |
APPL NO | 15/364953 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/32 (20130101) Original (OR) Class C07K 16/2833 (20130101) C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/56 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) C07K 2317/622 (20130101) C07K 2317/732 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041044 | Walsh et al. |
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FUNDED BY |
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APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | Kenneth Walsh (Carlisle, Massachusetts); Jose Fuster (Brighton, Massachusetts) |
ABSTRACT | As demonstrated herein, a preferential and progressive expansion of a subset of hematopoietic cells bearing somatic mutations in TET2 leads to pro-inflammatory IL-1β signaling at multiple levels, including increased IL-1β transcription, increased NLRP3 inflammasome-mediated IL-1β secretion, and increased IL-1-Receptor 1-mediated IL-1β signaling. Accordingly, provided herein are compositions, methods, and assays for modulating TET2 mutation-mediated IL-1β (interleukin-1β) proinflammatory activity, particularly when caused by somatic mutations in TET2. |
FILED | Friday, July 28, 2017 |
APPL NO | 15/662546 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) A61K 2035/124 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/244 (20130101) C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041045 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey); HACKENSACK UNIVERSITY MEDICAL CENTER (Hackensack, New Jersey) |
ASSIGNEE(S) | HACKENSACK UNIVERSITY MEDICAL CENTER (Hackensack, New Jersey); THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
INVENTOR(S) | Woo Young Lee (Lyndhurst, New Jersey); Yexin Gu (North Bergen, New Jersey); Qiaoling Sun (Secaucus, New Jersey); Wenting Zhang (Kearny, New Jersey); Jenny Zilberberg (Yardley, Pennsylvania) |
ABSTRACT | A bed of microbeads is used as a foundation for reconstructing a three-dimensional osteocyte network by culturing osteocytes within the bed. The osteocytes are cultured such that they form a network among the microbeads that is capable of simulating the osteocyte network of natural bone. The osteocytes are cultured in a microfluidic device adapted for the purpose. |
FILED | Friday, September 19, 2014 |
APPL NO | 14/490847 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 25/16 (20130101) C12M 29/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0654 (20130101) Original (OR) Class C12N 2531/00 (20130101) C12N 2533/54 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5026 (20130101) G01N 33/5044 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041046 | Karp et al. |
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FUNDED BY |
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APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Jeffrey Michael Karp (Brookline, Massachusetts); Xiaolei Yin (Quincy, Massachusetts); Marc David Succi (Boston, Massachusetts); Robert Samuel Langer (Newton, Massachusetts) |
ABSTRACT | Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation. A single layer of epithelial cells that actively self-renews and is organized into crypts and villi clothes the intestine. It has been recently shown that the renewal of intestinal epithelium is driven by Lgr5+ intestinal stem cells (ISC) that reside at the base of these crypts (Barker et al., 2007). Lgr5+ stem cells can be isolated and cultured in vitro to form organoids containing crypt-vcllus structures that recapitulates the native intestinal epithelium (Sato et al., 2009). |
FILED | Tuesday, March 11, 2014 |
APPL NO | 14/775560 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/068 (20130101) Original (OR) Class C12N 5/0679 (20130101) C12N 2501/11 (20130101) C12N 2501/42 (20130101) C12N 2501/065 (20130101) C12N 2501/73 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2513/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041047 | Karp et al. |
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FUNDED BY |
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APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Jeffrey Michael Karp (Brookline, Massachusetts); Xiaolei Yin (Quincy, Massachusetts); Marc David Succi (Boston, Massachusetts); Robert Samuel Langer (Newton, Massachusetts) |
ABSTRACT | Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation. |
FILED | Friday, April 21, 2017 |
APPL NO | 15/494291 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/506 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/068 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/42 (20130101) C12N 2501/065 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2513/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041048 | Schlegel et al. |
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FUNDED BY |
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APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
INVENTOR(S) | Richard Schlegel (Rockville, Maryland); Xuefeng Liu (Gaithersburg, Maryland) |
ABSTRACT | The present invention is directed towards methods of culturing non-keratinocyte epithelial cells, with the methods comprising culturing non-keratinocyte epithelial cells in the presence of feeder cells and a calcium-containing medium while inhibiting the activity of Rho kinase (ROCK) in the feeder cell, the non-keratinocyte epithelial cells or both during culturing. |
FILED | Wednesday, February 10, 2016 |
APPL NO | 15/040770 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) C12N 5/0625 (20130101) C12N 5/0631 (20130101) C12N 5/0683 (20130101) Original (OR) Class C12N 5/0688 (20130101) C12N 2500/05 (20130101) C12N 2500/40 (20130101) C12N 2501/01 (20130101) C12N 2501/11 (20130101) C12N 2501/33 (20130101) C12N 2501/39 (20130101) C12N 2501/727 (20130101) C12N 2502/13 (20130101) C12N 2502/1323 (20130101) C12N 2503/02 (20130101) C12N 2510/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041057 | Gomelsky et al. |
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FUNDED BY |
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APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
INVENTOR(S) | Mark Gomelsky (Laramie, Wyoming); Min-Hyung Ryu (Laramie, Wyoming) |
ABSTRACT | Methods and constructs are provided for controlling processes in live animals, plants or microbes via genetically engineered near-infrared light-activated or light-inactivated proteins including chimeras including the photosensory modules of bacteriohytochromes and output modules that possess enzymatic activity and/or ability to bind to DNA, RNA, protein, or small molecules. DNA encoding these proteins are introduced as genes into live animals, plants or microbes, where their activities can be turned on by near-infrared light, controlled by the intensity of light, and turned off by near-infrared light of a different wavelength than the activating light. These proteins can regulate diverse cellular processes with high spatial and temporal precision, in a nontoxic manner, often using external light sources. For example, near-infrared light-activated proteins possessing nucleotidyl cyclase, protein kinase, protease, DNA-binding and RNA-binding activities are useful to control signal transduction, cell apoptosis, proliferation, adhesion, differentiation and other cell processes. |
FILED | Tuesday, January 19, 2016 |
APPL NO | 15/000896 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) A61K 31/713 (20130101) A61K 38/51 (20130101) A61K 38/164 (20130101) A61K 41/00 (20130101) A61K 48/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0659 (20130101) Peptides C07K 7/06 (20130101) C07K 14/195 (20130101) C07K 2319/00 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/50 (20130101) C12N 9/88 (20130101) Original (OR) Class C12N 9/6472 (20130101) C12N 9/6475 (20130101) C12N 15/62 (20130101) Enzymes C12Y 114/14 (20130101) C12Y 304/22056 (20130101) C12Y 406/01001 (20130101) C12Y 406/01002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 33/5088 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041071 | Rossi et al. |
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FUNDED BY |
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APPLICANT(S) | City of Hope (Duarte, California) |
ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | John J. Rossi (Alta Loma, California); Jiehua Zhou (Duarte, California) |
ABSTRACT | The present invention relates to compositions and methods for delivery of siRNA to specific cells or tissue. More particularly, the present invention relates to compositions and methods for cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 aptamer. |
FILED | Monday, November 28, 2016 |
APPL NO | 15/362168 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1132 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/531 (20130101) C12N 2310/533 (20130101) C12N 2310/3519 (20130101) C12N 2320/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041072 | Lois-Caballe et al. |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Carlos Lois-Caballe (Cambridge, Massachusetts); David Baltimore (Pasadena, California); Xiao-Feng Qin (Sugarland, Texas); Irvin S. Y. Chen (Palos Verdes Estates, California); Dong Sung An (Los Angeles, California) |
ABSTRACT | In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A). Small interfering RNA (siRNA) can be expressed using the methods of the invention within a cell. In a further aspect, the invention provides methods for producing siRNA encoding lentivirus where the siRNA activity may interfere with the lentiviral life cycle. In yet a further aspect, the invention provides methods for expression of a small RNA molecule within a cell, such as an siRNA capable of downregulating CCR5, wherein expression of the small RNA molecule is relatively non-cytotoxic to the cell. The invention also includes small RNA molecules, such as an siRNA capable of downregulating CCR5, that are relatively non-cytotoxic to cells. |
FILED | Friday, December 30, 2016 |
APPL NO | 15/395348 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/1132 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/111 (20130101) C12N 2740/16043 (20130101) C12N 2740/16045 (20130101) C12N 2799/027 (20130101) C12N 2810/609 (20130101) C12N 2830/003 (20130101) C12N 2830/008 (20130101) C12N 2840/203 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041075 | Lutz et al. |
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APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Gordon J. Lutz (Kennett Square, Pennsylvania); Melanie K. Tallent (Kennett Square, Pennsylvania); Nicole Michele Lykens (Woodbury, New Jersey) |
ABSTRACT | The present invention encompasses a class of compounds known as splice modulating oligonucleotides (SMOs) that modulate pre-mRNA splicing, thereby affecting expression and functionality of a specific protein in a cell. The present invention further provides compositions and methods for modulating pre-mRNA splicing using a SMO of the invention to abrogate disease-causing mutations in a protein. Accordingly, the present invention provides compositions and methods of treating a subject at risk of, susceptible to, or having a disease, disorder, or condition associated with aberrant or unwanted target pre-mRNA expression or activity. |
FILED | Wednesday, December 06, 2017 |
APPL NO | 15/833539 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 15/1137 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2320/33 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041105 | Li |
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APPLICANT(S) | CELLEX, INCORPORATED (Cary, North Carolina) |
ASSIGNEE(S) | CELLEX, INCORPORATED (Cary, North Carolina) |
INVENTOR(S) | Xingxiang Li (Cary, North Carolina) |
ABSTRACT | Embodiments described herein relate to assay methods and kits for detecting resistance of any enzyme to its inhibitor due to functional alteration of the enzyme, comprising, conducting two or more reactions with two or more reagent mixes optionally containing substrates for the enzyme. The mixes are substantially similar, except that one contains no enzyme inhibitor whereas the others contain an enzyme inhibitor being tested for resistance. The ratio of the signal from the reaction with an inhibitor to that from a reaction without an inhibitor is used to indicate whether the enzyme is resistant to the enzyme inhibitor and also determine the susceptibility or resistance of the enzyme to various inhibitors and further identify enzyme variants. Embodiments further relate to assay methods comprising only two reactions—one conducted in a mix containing the inhibitor and the other without the inhibitor. Further included are devices for conducting such assays. |
FILED | Monday, April 13, 2015 |
APPL NO | 14/684938 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 21/76 (20130101) G01N 21/763 (20130101) G01N 2333/11 (20130101) G01N 2333/986 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041107 | Kazakov et al. |
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APPLICANT(S) | SomaGenics, Inc. (Santa Cruz, California) |
ASSIGNEE(S) | SOMAGENICS, INC. (Santa Cruz, California) |
INVENTOR(S) | Sergei A. Kazakov (San Jose, California); Pavan Kumar (Arlington, Massachusetts); Brian H. Johnston (Scotts Valley, California) |
ABSTRACT | Currently, the circularization of small RNAs is broadly regarded as an obstacle in ligation-related assays and explicitly avoided while short lengths of linear RNA targets is broadly recognized as a factor limiting use of conventional primers in PCR-related assays. In contrast, the disclosed invention capitalizes on circularization of small RNA targets or their conjugates with oligonucleotide adapters. The circular RNA templates provide amplification of the target sequences via synthesis of multimer nucleic acids that can be either labeled for direct detection or subjected to PCR amplification and detection. Structure of small circular RNAs and corresponding multimeric nucleic acids provide certain advantages over current methods including flexibility in design of conventional RT and PCR primers as well as use of 5′-overlapping dimer-primers for efficient and sequence-specific amplification of short target sequences. Our invention also reduces number of steps and reagents while increasing sensitivity and accuracy of detection of small RNAs with both 2′OH and 2′-OMe at their 3′ ends. Our invention increase sensitivity and specificity of detection of microRNAs and other small RNAs with both 2′OH and 2′-OMe at their 3′ ends while allowing us to distinguish these two forms from each other. |
FILED | Thursday, October 06, 2016 |
APPL NO | 15/287254 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6865 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041108 | Barish et al. |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Robert Barish (Tokyo, Japan); Peng Yin (Brookline, Massachusetts) |
ABSTRACT | This disclosure provides methods for generating super-resolution patterns of molecules on substrates. In one aspect, disclosed herein is a method comprising contacting a plurality of transiently binding nucleic acid probes to their respective targets wherein the targets are immobilized on a substrate, detecting a binding event in a select region or set of select regions within a diffraction limited region of the substrate, and irradiating the diffraction limited region of the substrate, wherein the probes comprise a photocrosslinker. In one embodiment, the photocrosslinker is 3-cyanovinylcarbazole. |
FILED | Monday, December 15, 2014 |
APPL NO | 15/104570 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6834 (20130101) Original (OR) Class C12Q 1/6834 (20130101) C12Q 2563/107 (20130101) C12Q 2565/601 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/77 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 2021/7786 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041112 | Wang et al. |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Pioneer Hi-Bred International, Inc. (Johnston, Iowa) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Pioneer Hi-Bred International, Inc. (Johnston, Iowa) |
INVENTOR(S) | Tza-Huei J. Wang (Baltimore, Maryland); Kuangwen Hsieh (Germantown, Maryland); Helena C. Zec (Baltimore, Maryland); Lingshu Liu (Baltimore, Maryland); Aniruddha M. Kaushik (Baltimore, Maryland); Yue Yun (Johnston, Iowa) |
ABSTRACT | The present application relates to a continuous droplet flow microfluidic system, including a microfluidic chip including an optical detection section; a stage assembly including a microfluidic chip holder configured to receive the microfluidic chip and a plurality of heating elements arranged to heat a plurality of separate sections of the microfluidic chip to a corresponding plurality of different temperatures; and an optical detection system arranged to detect fluorescent light emitted from said optical detection section of the microfluidic chip. |
FILED | Wednesday, April 13, 2016 |
APPL NO | 15/097904 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0241 (20130101) B01L 3/502784 (20130101) B01L 7/525 (20130101) B01L 2200/0673 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2300/0877 (20130101) B01L 2300/0883 (20130101) B01L 2300/1822 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/686 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2531/113 (20130101) C12Q 2535/122 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041123 | Chinnaiyan et al. |
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APPLICANT(S) | Arul M. Chinnaiyan (Plymouth, Michigan); Scott Tomlins (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Arul M. Chinnaiyan (Plymouth, Michigan); Scott Tomlins (Ann Arbor, Michigan) |
ABSTRACT | Recurrent gene fusions in prostate cancer of androgen regulated genes or housekeeping genes and ETS family member genes are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided. |
FILED | Friday, July 06, 2007 |
APPL NO | 11/825552 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041129 | Mulé et al. |
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APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
INVENTOR(S) | James J. Mulé (Odessa, Florida); Domenico Coppola (Tampa, Florida); Timothy J. Yeatman (Thonotosassa, Florida); Andrey Loboda (Philadelphia, Pennsylvania); Michael V. Nebozhyn (Yeadon, Pennsylvania) |
ABSTRACT | This invention relates to methods for selecting a treatment, treating, and predicting survival time in subjects with cancer, such as colorectal cancer, based on tumor expression levels of chemokines, cytotoxic genes, and/or dendritic cell genes. |
FILED | Thursday, June 02, 2016 |
APPL NO | 15/171713 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5743 (20130101) G01N 33/57407 (20130101) G01N 33/57415 (20130101) G01N 33/57419 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041910 | Doyle et al. |
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APPLICANT(S) | Timothy E. Doyle (Springville, Utah); Leigh A. Neumayer (Salt Lake City, Utah) |
ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah); UTAH STATE UNIVERSITY (North Logan, Utah) |
INVENTOR(S) | Timothy E. Doyle (Springville, Utah); Leigh A. Neumayer (Salt Lake City, Utah) |
ABSTRACT | A method for determining a pathology of a tissue sample. The method includes steps of coupling the tissue sample between two oppositely-facing ultrasonic transducers; acquiring a pulse-echo ultrasonic measurement and a through-transmission ultrasonic measurement of the tissue sample using the ultrasonic transducers; analyzing at least one of the pulse-echo ultrasonic measurement and the through-transmission ultrasonic measurement using time domain analysis; analyzing at least one of the through-transmission ultrasonic measurements and the pulse-echo ultrasonic measurements using frequency domain analysis; and determining the pathology of the tissue sample based on at least one of the time domain analysis and the frequency domain analysis. |
FILED | Monday, November 14, 2011 |
APPL NO | 13/885274 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) Original (OR) Class G01N 29/11 (20130101) G01N 29/46 (20130101) G01N 2291/102 (20130101) G01N 2291/02475 (20130101) G01N 2291/02854 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041936 | Isacoff et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
INVENTOR(S) | Ehud Y. Isacoff (Berkeley, California); Sophie Pautot (Dresden, Germany) |
ABSTRACT | The present invention provides methods for culturing neuronal cells for transplantation into a subject. The methods include culturing neuronal cells with microparticles to provide a microparticle and neuronal cell culture composition, wherein the microparticles are coated with a compound that provides for attachment of neuronal cells. The present invention also provides methods of screening the cultured neuronal cells as well as kits and systems for use in the same. |
FILED | Monday, July 13, 2015 |
APPL NO | 14/798053 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 2501/06 (20130101) C12N 2533/12 (20130101) C12N 2533/32 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5058 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041938 | Rao et al. |
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APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
INVENTOR(S) | Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland) |
ABSTRACT | Provided herein are methods and kits for measuring a level of a 5-hydroxymethylcytosine in a nucleotide sequence from a subject, wherein the subject is a subject having a cancer or suspected of having cancer. |
FILED | Thursday, February 23, 2017 |
APPL NO | 15/440826 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) Original (OR) Class G01N 33/57484 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041945 | Rengarajan et al. |
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APPLICANT(S) | Emory University (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Jyothi Rengarajan (Decatur, Georgia); Toidi Adekambi (Atlanta, Georgia); Christian C. Ibegbu (Stockbridge, Georgia) |
ABSTRACT | This disclosure relates to methods of treating and diagnosing a tuberculosis infection as pulmonary active or latent based on biomarkers expressed on pools of CD4+ cells. In certain embodiments, the disclosure relates to methods of treatment of a subject diagnosed with tuberculosis comprising the steps of, measuring a pool of CD4 IFN-γ cells for cells that also express CD38, HLA-DR, and/or Ki-67 providing a measurement; associating an increased measurement of CD4 IFN-γ cells that also express CD38, HLA-DR, Ki-67, compared to a control, as an indication that the subject has active tuberculosis; and treating the subject with an aggressive tuberculosis treatment. |
FILED | Tuesday, May 05, 2015 |
APPL NO | 15/309403 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/133 (20130101) A61K 31/133 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4409 (20130101) A61K 31/4409 (20130101) A61K 31/4965 (20130101) A61K 31/4965 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 33/56972 (20130101) Original (OR) Class G01N 2333/35 (20130101) G01N 2333/47 (20130101) G01N 2333/57 (20130101) G01N 2333/70514 (20130101) G01N 2333/70539 (20130101) G01N 2333/70596 (20130101) G01N 2800/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041949 | Bendall et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Sean C. Bendall (San Mateo, California); Garry P. Nolan (Redwood City, California); Robert M. Angelo (San Francisco, California) |
ABSTRACT | A method of generating a high resolution two-dimensional image of a sample comprising cells and extracellular structures is provided. In certain embodiments, the method comprises: labeling a sample with at least one mass tag, thereby producing a labeled sample; scanning the sample with a secondary ion mass spectrometer (SIMS) ion beam to generate a data set that comprises spatially-addressable measurements of the abundance of the mass tag across an area of the sample; and outputting the data set. In many embodiments, the data set contains the identity and abundance of the mass tag. A system for performing the method is also provided. |
FILED | Thursday, September 11, 2014 |
APPL NO | 14/483999 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 33/58 (20130101) Original (OR) Class G01N 33/483 (20130101) G01N 33/5005 (20130101) G01N 33/6848 (20130101) G01N 33/48735 (20130101) G01N 2015/1006 (20130101) G01N 2458/15 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041951 | Yi et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Hyunjung Yi (Cambridge, Massachusetts); Debadyuti Ghosh (Cambridge, Massachusetts); Jifa Qi (Cambridge, Massachusetts); Angela M. Belcher (Lexington, Massachusetts); Michael S. Strano (Lexington, Massachusetts); Neelkanth M. Bardhan (Cambridge, Massachusetts) |
ABSTRACT | An imaging probe can include a photoluminescent carbon nanostructure configured to emit a wavelength of light detectable through living tissue, and a targeting moiety including a first binding partner configured to interact with a second binding partner. |
FILED | Thursday, January 31, 2013 |
APPL NO | 13/755613 |
ART UNIT | 1678 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0017 (20130101) A61K 49/0056 (20130101) A61K 49/0058 (20130101) A61K 49/0095 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/927 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041956 | Merchant et al. |
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APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Michael L. Merchant (Louisville, Kentucky); Jon B. Klein (Louisville, Kentucky); Michael E. Brier (Sellersburg, Indiana); Adam E. Gaweda (Jeffersonville, Indiana) |
ABSTRACT | Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent. |
FILED | Thursday, May 14, 2015 |
APPL NO | 14/712323 |
ART UNIT | 1678 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/6863 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042025 | Samsonov |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Alexey A. Samsonov (Madison, Wisconsin) |
ABSTRACT | A system and method is provided for producing a map of a static magnetic field (B0) of a magnetic resonance imaging system. The method includes forming a first dataset by acquiring, with the MRI system, a first plurality of different echo signals occurring at a respective plurality of different echo times. The method also includes forming a second dataset by acquiring, with the MRI system, a second plurality of different echo signals occurring at a respective plurality of different echo times. The second dataset includes signals resulting from a magnetization transfer (MT) between free water and bound molecules. The method further includes generating MT-weighted maps using the first dataset and the second dataset, determining, using the MT-weighted maps, a phase difference between the first plurality of different echo signals, and using the phase differences, generate a corrected map of the static magnetic field (B0) of the MRI system. |
FILED | Thursday, June 02, 2016 |
APPL NO | 15/172122 |
ART UNIT | 2867 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/485 (20130101) Original (OR) Class G01R 33/4828 (20130101) G01R 33/5614 (20130101) G01R 33/5615 (20130101) G01R 33/56563 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042149 | Shroff et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Hari Shroff (Washington, District of Columbia); Andrew York (Bethesda, Maryland) |
ABSTRACT | A multi-focal selective illumination microscopy (SIM) system for generating multi-focal patterns of a sample is disclosed. The multi-focal SIM system performs a focusing, scaling and summing operation on each multi-focal pattern in a sequence of multi-focal patterns that completely scan the sample to produce a high resolution composite image. |
FILED | Thursday, June 01, 2017 |
APPL NO | 15/610906 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 2021/6478 (20130101) G01N 2201/0633 (20130101) Optical Elements, Systems, or Apparatus G02B 21/004 (20130101) G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/0072 (20130101) Original (OR) Class G02B 21/0076 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042977 | Hebert et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | James R. Hebert (Columbia, South Carolina); Azza Shoaibi (Cayce, South Carolina) |
ABSTRACT | A method for detecting aggressive prostate cancer is described, for instance for use in determination of the need for biopsy based. Disclosed methods recognize the difference in PSA rate of change for men in different prostate health states and having different risk profiles so as to provide a route for earlier detection of aggressive prostate cancer, for example in asymptomatic men. |
FILED | Tuesday, September 15, 2015 |
APPL NO | 14/854371 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Electric Digital Data Processing G06F 19/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043135 | Michelson et al. |
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FUNDED BY |
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APPLICANT(S) | InferLink Corporation (El Segundo, California) |
ASSIGNEE(S) | InferLink Corporation (El Segundo, California) |
INVENTOR(S) | Matthew Michelson (La Canada, California); Steven Minton (El Segundo, California) |
ABSTRACT | Textual information extraction, parsing, and inferential analysis systems and methods are provided herein. An example method includes extracting content for each of a plurality of types from a corpus of textual information, the plurality of types corresponding to segments of an inference scheme, the inference scheme including a dependency that orders the segments together so as to create a summation of the corpus of textual information when the extracted content is assembled, and assembling one or more inferred statements using the inference scheme and the extracted content. |
FILED | Tuesday, January 31, 2017 |
APPL NO | 15/421166 |
ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
CURRENT CPC | Electric Digital Data Processing G06F 17/30719 (20130101) G06F 19/324 (20130101) G06F 19/325 (20130101) G06F 19/3443 (20130101) Computer Systems Based on Specific Computational Models G06N 5/048 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/70 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043250 | Udupa et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Jayaram K. Udupa (Philadelphia, Pennsylvania); Dewey Odhner (Horsham, Pennsylvania); Yubing Tong (Norwood, Pennsylvania); Drew A. Torigian (Philadelphia, Pennsylvania) |
ABSTRACT | Interactive non-uniformity correction (NC) and interactive intensity standardization (IS) require sample tissue regions to be specified for several different types of tissues. Interactive NC estimates the degree of non-uniformity at each voxel in a given image, builds a global function for non-uniformity correction, and then corrects the image to improve quality. Interactive IS includes two steps: a calibration step and a transformation step. In the first step, tissue intensity signatures of each tissue from a few subjects are utilized to set up key landmarks in a standardized intensity space. In the second step, a piecewise linear intensity mapping function is built between the same tissue signatures derived from the given image and those in the standardized intensity space to transform the intensity of the given image into standardized intensity. Interactive IS for MR images combined with interactive NC can substantially improve numeric characterization of tissues. |
FILED | Friday, March 25, 2016 |
APPL NO | 15/080871 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 5/009 (20130101) Original (OR) Class G06T 5/50 (20130101) G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/20208 (20130101) G06T 2207/30024 (20130101) G06T 2207/30168 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 10039445 | Torch |
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FUNDED BY |
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APPLICANT(S) | William C. Torch (Reno, Nevada) |
ASSIGNEE(S) | Google LLC (Mountain View, California) |
INVENTOR(S) | William C. Torch (Reno, Nevada) |
ABSTRACT | Biosensor, communicator, and/or controller apparatus, systems, and methods are provided for monitoring movement of a person's eye. The apparatus includes a device configured to be worn on a user's head, a light source for directing light towards one or both eyes of the user, one or more image guides on the device for viewing one or both eyes of the user, and one or more cameras carried on the device and coupled to the image guides for acquiring images of the eyes and/or the user's surroundings. The apparatus may include a cable and/or a transmitter for transmitting image data from the camera to a remote location, e.g., to processor and/or display for analyzing and/or displaying the image data. A system including the apparatus may be used to monitor one or more oculometric parameters, e.g., pupillary response, and/or to control a computer using the user's eyes instead of a mouse. |
FILED | Wednesday, January 13, 2010 |
APPL NO | 12/687125 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00009 (20130101) A61B 3/0025 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039813 | Goosens |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Ki Ann Goosens (Cambridge, Massachusetts) |
ABSTRACT | The invention relates to methods of protecting against chronic stress in a subject and treating stress sensitive disorders in a subject by antagonizing ghrelin or ghrelin receptor. |
FILED | Thursday, February 07, 2013 |
APPL NO | 14/377229 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1796 (20130101) A61K 39/00 (20130101) A61K 39/0005 (20130101) Original (OR) Class A61K 45/00 (20130101) A61K 2039/545 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 2333/60 (20130101) G01N 2800/7004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039820 | Coller et al. |
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FUNDED BY |
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APPLICANT(S) | HAWAII BIOTECH, INC. (Honolulu, Hawaii) |
ASSIGNEE(S) | Hawaii Biotech, Inc. (Honolulu, Hawaii) |
INVENTOR(S) | Beth-Ann Coller (West Point, Pennsylvania); Vidya Pai (Bethesda, Maryland); Carolyn L. Weeks-Levy (Honolulu, Hawaii); Steven A. Ogata (Kailua, Hawaii) |
ABSTRACT | A West Nile virus vaccine for human use is described that preferably contains a recombinantly produced form of truncated West Nile virus envelope glycoprotein and aluminum adjuvant. The vaccine is acceptable for use in the general population, including immunosuppressed, immunocompromised, and immunosenescent individuals. The vaccine is safe and effective for use in all healthy and at-risk populations. A pharmaceutically acceptable vehicle may also be included in the vaccine. |
FILED | Friday, October 21, 2016 |
APPL NO | 15/331596 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/55505 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/24134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039848 | Brown et al. |
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FUNDED BY |
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APPLICANT(S) | AEROCLAVE, LLC (Winter Park, Florida) |
ASSIGNEE(S) | Aeroclave, LLC (Winter Park, Florida) |
INVENTOR(S) | Ronald D. Brown (Maitland, Florida); Paul M. Gray (Ocoee, Florida); James S. Amrhein (Oviedo, Florida) |
ABSTRACT | A reusable portable decontamination system is provided for a transportation asset. The decontamination system includes a plurality of insulated panels detachably secured together to form an enclosure for the transportation asset and other equipment. The decontamination system also includes a humidifying module in fluid communication with an interior of the enclosure to raise a temperature and a humidity of the interior of the enclosure to a predetermined temperature level and a predetermined humidity level for a timed duration. Additionally, the decontamination system includes a dehumidifying module in fluid communication with the interior of the enclosure to lower the temperature and the humidity of the interior of the enclosure from the predetermined temperature level and the predetermined humidity level to ambient levels. A storage and decontamination module is also presented, to decontaminate one or more components of a transportation asset. |
FILED | Tuesday, June 23, 2015 |
APPL NO | 14/747195 |
ART UNIT | 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/07 (20130101) Original (OR) Class A61L 2/20 (20130101) A61L 2/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039850 | Taggart et al. |
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FUNDED BY |
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APPLICANT(S) | STERIO3, LLC (Madison, Wisconsin) |
ASSIGNEE(S) | STERIO3, LLC (Madison, Wisconsin) |
INVENTOR(S) | Daniel S. Taggart (Salt Lake City, Utah); Jessica I. McKelvie (Salt Lake City, Utah); James J. Steppan (Park City, Utah); Thomas R. Hinklin (Sandy, Utah); Chett J. Boxley (Park City, Utah) |
ABSTRACT | Embodiments of the present disclosure generally relate to devices and methods for sterilizing equipment. More particularly, one or more embodiments described in the present disclosure are directed to portable devices for sterilizing medical equipment in emergency situations. The sterilization devices and method of the present disclosure address an unmet need for sterilizing surgical equipment in a manner that is not only effective and time-efficient, but is also portable and reliable enough to use in emergency medical situations in remote locations where modern sterilization equipment is not available. |
FILED | Thursday, July 13, 2017 |
APPL NO | 15/649447 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/22 (20130101) Original (OR) Class A61L 2/24 (20130101) A61L 2202/11 (20130101) A61L 2202/14 (20130101) A61L 2202/15 (20130101) A61L 2202/16 (20130101) A61L 2202/24 (20130101) A61L 2202/122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039916 | Jirjis |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Michael B Jirjis (San Antonio, Texas) |
ABSTRACT | An implantable high voltage electrode includes a shaft having a first end and a second end and an ellipsoid tip disposed at the first end. A terminal is disposed at the second end and the terminal in in electrical communication with the ellipsoid tip. At least a first forward facing barb and at least a first aft facing barb disposed on an exterior face of the shaft. The at least first forward facing bard and the at least first aft facing barb are configured to limit movement of the electrode when implanted in biological tissue. |
FILED | Wednesday, September 21, 2016 |
APPL NO | 15/271298 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0504 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040062 | Beebe et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Ben P. Casavant (Madison, Wisconsin); David J. Guckenberger (Oconomowoc, Wisconsin); Scott M. Berry (Madison, Wisconsin) |
ABSTRACT | A device and method are proved for transferring a target from a first location to a second location. The target is bound to solid phase substrate to form a target bound solid phase substrate. The device includes transfer surface for receiving the target bound solid phase substrate thereon for transfer. The transfer surface movable between a first position wherein the transfer surface is aligned with the first location and spaced therefrom by a distance and a second position wherein the transfer surface is aligned with the second location. An alignment structure aligns the transfer surface with respect to the second location, with the transfer surface in the second position. A force is movable between an attraction position wherein the target bound solid phase substrate are drawn toward the transfer surface and a discharge position wherein the target bound solid phase substrate are free of the force. |
FILED | Tuesday, January 14, 2014 |
APPL NO | 14/154695 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 3/563 (20130101) B01L 3/5088 (20130101) B01L 3/50825 (20130101) B01L 2200/025 (20130101) B01L 2200/0657 (20130101) B01L 2200/0668 (20130101) B01L 2300/042 (20130101) B01L 2400/021 (20130101) B01L 2400/043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040069 | Moore et al. |
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FUNDED BY |
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APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York); University of Washington (Seattle, Washington) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | David Roger Moore (Schenectady, New York); Matthew Jeremiah Misner (Delanson, New York); Andrew Arthur Paul Burns (Schenectady, New York); Joshua Bishop (Seattle, Washington); Lisa K. Lafleur (Seattle, Washington); Maxwell Wheeler (Seattle, Washington) |
ABSTRACT | The present disclosure relates to a sample assessment device. By way of example, the sample assessment device may include a substrate including a sample application region; an amplification region comprising a plurality of amplification reagents; a waste region comprising an entrance fluidically coupled to the amplification region and extending away from the amplification region; and a detection region spaced apart from the amplification region. The sample assessment device may also include a valve coupled to the substrate and configured to separate the amplification region from the detection region in a closed configuration, wherein the amplification region and the valve are positioned on the sample assessment device between the sample application region and the detection region and wherein the sample assessment device is configured to permit lateral flow from the amplification region to the detection region when the valve is in an open configuration. |
FILED | Thursday, July 23, 2015 |
APPL NO | 14/807497 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 3/502738 (20130101) B01L 7/52 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/027 (20130101) B01L 2300/18 (20130101) B01L 2300/126 (20130101) B01L 2300/0627 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0874 (20130101) B01L 2300/0887 (20130101) B01L 2400/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040146 | Squier et al. |
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FUNDED BY |
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APPLICANT(S) | Colorado School of Mines (Golden, Colorado) |
ASSIGNEE(S) | COLORADO SCHOOL OF MINES (Golden, Colorado) |
INVENTOR(S) | Jeff A. Squier (Golden, Colorado); Erica K. Block (Golden, Colorado) |
ABSTRACT | A multipass chirped pulse amplification system outfitted with a single-grating, simultaneous spatial and temporal focusing (SSTF) compressor platform is provided. Such a system provides the ability to vary the beam aspect ratio of an SSTF beam, and thus the degree of pulse-front tilt at a focus, while maintaining a net zero-dispersion system. The optical system may include a first optical element or set of optical elements that receives and then varies a pulse-front tilt of a light beam, and a second optical element or set of optical elements that focuses the light beam having the varied pulse-front tilt that is output by the first optical element or set of optical elements. The first optical element or set of optical elements includes an optical grating, two dihedrals, and a retroflector roof mirror. |
FILED | Monday, December 14, 2015 |
APPL NO | 14/968633 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/362 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/00 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) H01S 3/2325 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040534 | Kooiman et al. |
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FUNDED BY |
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APPLICANT(S) | Bell Helicopter Textron Inc. (Fort Worth, Texas) |
ASSIGNEE(S) | BELL HELICOPTER TEXTRON INC. (Fort Worth, Texas) |
INVENTOR(S) | James Everett Kooiman (Fort Worth, Texas); Mark Loring Isaac (Fort Worth, Texas); John Elton Brunken, Jr. (Colleyville, Texas); John McCullough (Weatherford, Texas) |
ABSTRACT | According to one embodiment, an aircraft features a fuselage, a wing member, and two fuselage beam. The fuselage features a first plurality of structural supports, a second plurality of structural supports, a first opening disposed between the first plurality of structural supports, and a second opening disposed between the second plurality of structural supports. The wing member is disposed above the first opening and above the second opening. The wing features a plurality of ribs including a first rib and a second rib. The first fuselage beam couples the first rib of the wing member to the fuselage and has an elongated body portion extending across the first plurality of structural supports. The second fuselage beam couples the second rib of the wing member to the fuselage and features an elongated body portion extending across the second plurality of structural supports. |
FILED | Monday, December 07, 2015 |
APPL NO | 14/960648 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 1/26 (20130101) Original (OR) Class B64C 1/1423 (20130101) B64C 3/187 (20130101) B64C 29/0033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040549 | Sarigul-Klijn et al. |
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FUNDED BY |
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APPLICANT(S) | Martinus M. Sarigul-Klijn (Dixon, California); Maurice P. Gionfriddo (Dixon, California); Nesrin Sarigul-Klijn (Dixon, California) |
ASSIGNEE(S) | Logistic Gliders Inc. (Dixon, California) |
INVENTOR(S) | Martinus M. Sarigul-Klijn (Dixon, California); Maurice P. Gionfriddo (Dixon, California); Nesrin Sarigul-Klijn (Dixon, California) |
ABSTRACT | A disposable airdropped glider. The glider body is constructed from precut panels cut from (MDO) or (HDO) plywood and assembled with pocket-screw joinery or piano hinges. A skid board forms a landing surface and a cargo deck roll-off surface. The glider has pivoting wings and struts. The glider has a triple-tail, a flat nose and honeycomb paperboard panels between the nose and the cargo. Wings are pivoted from a position overlying the fuselage to a flying position by gas springs in wing spars which are compressed by a chain attached to the fuselage through a rotating bracket such that the gas springs are compressed when the wings are folded. The airfoils are plastic extrusions with openings that hold the wing spars and co-formed jury spars which attach the upper and lower surface of the wing. A parachute uses a part of the tail structure to form a deployment drogue. |
FILED | Monday, September 25, 2017 |
APPL NO | 15/715016 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 3/56 (20130101) B64C 3/185 (20130101) B64C 25/52 (20130101) B64C 31/02 (20130101) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 17/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040575 | Franich et al. |
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FUNDED BY |
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APPLICANT(S) | Goodrich Lighting Systems, Inc. (Oldsmar, Florida) |
ASSIGNEE(S) | GOODRICH LIGHTING SYSTEMS, INC. (Oldsmar, Florida) |
INVENTOR(S) | David Franich (Tempe, Arizona); Philippe Lapujade (Chandler, Arizona) |
ABSTRACT | A dual mode light assembly for a forward position light of an aircraft includes a base, a visible light source mounted to the base that is configured to emit visible light, a covert light source mounted to the base that is configured to emit covert light, and a light shield mounted to the base. The light shield is configured to restrict transmission of the visible light to a visible light pattern and to restrict transmission of the covert light to a covert light pattern. |
FILED | Friday, July 15, 2016 |
APPL NO | 15/211164 |
ART UNIT | 2879 — Optics |
CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/06 (20130101) Original (OR) Class Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 7/00 (20130101) F21V 11/16 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems F21W 2101/06 (20130101) F21W 2107/30 (20180101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2115/10 (20160801) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040825 | Chan et al. |
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FUNDED BY |
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APPLICANT(S) | Yee-peng Chan (Bethesda, Maryland); Christopher Broder (Silver Spring, Maryland) |
ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
INVENTOR(S) | Yee-peng Chan (Bethesda, Maryland); Christopher Broder (Silver Spring, Maryland) |
ABSTRACT | This invention relates to soluble forms of F glycoprotein from Hendra and Nipah virus and to compositions comprising soluble forms of F glycoprotein from Hendra and Nipah virus. This invention further relates to soluble oligomers of F glycoprotein from Hendra and Nipah virus. This invention also relates to nucleic acids encoding soluble forms of F glycoprotein from Hendra and Nipah virus. This invention also relates to diagnostic and therapeutic methods using the soluble forms of F glycoprotein from Hendra and Nipah virus. Further, this invention relates to antibodies, including neutralizing antibodies, and to vaccines for the prevention, diagnosis and treatment of infection by Hendra and Nipah viruses. |
FILED | Friday, December 19, 2008 |
APPL NO | 12/808930 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/505 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/18222 (20130101) C12N 2760/18234 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040826 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Jerome Kim (Fort Detrick, Maryland); Stephen Harrison (Boston, Massachusetts); Barton F. Haynes (Durham, North Carolina); Georgia D. Tomaras (Durham, North Carolina); Nelson Michael (Fort Detrick, Maryland) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Jerome Kim (Fort Detrick, Maryland); Stephen Harrison (Boston, Massachusetts); Barton F. Haynes (Durham, North Carolina); Georgia D. Tomaras (Durham, North Carolina); Nelson Michael (Fort Detrick, Maryland) |
ABSTRACT | The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same. |
FILED | Thursday, July 05, 2012 |
APPL NO | 14/130338 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/6075 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/55 (20130101) C07K 2317/92 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16622 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040834 | Omenetto et al. |
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FUNDED BY |
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APPLICANT(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
ASSIGNEE(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
INVENTOR(S) | Fiorenzo Omenetto (Lexington, Massachusetts); David L. Kaplan (Concord, Massachusetts); Brian Lawrence (New York, New York); Mark Cronin-Golomb (Reading, Massachusetts) |
ABSTRACT | A method of manufacturing a biopolymer optofluidic device including providing a biopolymer, processing the biopolymer to yield a biopolymer matrix solution, providing a substrate, casting the biopolymer matrix solution on the substrate, embedding a channel mold in the biopolymer matrix solution, drying the biopolymer matrix solution to solidify biopolymer optofluidic device, and extracting the embedded channel mold to provide a fluidic channel in the solidified biopolymer optofluidic device. In accordance with another aspect, an optofluidic device is provided that is made of a biopolymer and that has a channel therein for conveying fluid. |
FILED | Monday, January 13, 2014 |
APPL NO | 14/154134 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) B29D 11/00663 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2211/04 (20130101) D10B 2401/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) G01N 33/5436 (20130101) G01N 33/54373 (20130101) G01N 33/54386 (20130101) G01N 2333/43578 (20130101) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 1/005 (20130101) G02B 1/06 (20130101) G02B 1/041 (20130101) G02B 1/045 (20130101) G02B 1/046 (20130101) G02B 5/18 (20130101) G02B 6/138 (20130101) G02B 2006/1213 (20130101) G02B 2006/12102 (20130101) G02B 2006/12104 (20130101) G02B 2006/12107 (20130101) G02B 2006/12171 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040993 | Brott |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Lawrence L. Brott (West Chester, Ohio) |
ABSTRACT | Chemiluminescent materials are provided that include an encapsulated oxalate-containing composition that includes a core portion and a polymeric coating, a peroxide source, and a fluorescent dye. The core portion includes an oxalate; a polymerizable component composition that polymerizes upon exposure to ultraviolet radiation; a photosensitizer; and an ultraviolet screening agent. The polymeric coating layer surrounding the core portion comprises a polymer derived from the polymerizable component composition. A fluorescent dye may be intermixed in the oxalate-containing composition, intermixed with the peroxide source, present in the chemiluminescent material as a separate dye layer or particle, or present within another component of the chemiluminescent material. A method for making the chemiluminescent material is also provided. |
FILED | Thursday, May 04, 2017 |
APPL NO | 15/586704 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/04 (20130101) B01J 13/185 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 3/36 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/07 (20130101) Original (OR) Class Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 2/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041067 | Murray et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Richard Martin Murray (Pasadena, California); Zachary Z. Sun (San Francisco, California) |
ABSTRACT | Provided herein are methods and compositions for rapid assembly of genetic modules, as well as seamless transition from in vitro to in vivo testing of genetic constructs. |
FILED | Wednesday, April 27, 2016 |
APPL NO | 15/140105 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/66 (20130101) C12N 15/1093 (20130101) Original (OR) Class C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2521/313 (20130101) C12Q 2521/501 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041092 | Horwitz et al. |
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FUNDED BY |
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APPLICANT(S) | Amyris, Inc. (Emeryville, California) |
ASSIGNEE(S) | AMYRIS, INC. (Emeryville, California) |
INVENTOR(S) | Andrew Horwitz (Emeryville, California); Kristy Michelle Hawkins (Emeryville, California); Max Schubert (Emeryville, California); Wayne Szeto (Emeryville, California) |
ABSTRACT | Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. In certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, a nuclease capable of causing a break at the genomic target site, and a linear nucleic acid capable of homologous recombination with itself or with one or more additional linear nucleic acids contacted with the population of cells, whereupon said homologous recombination results in formation of a circular extrachromosomal nucleic acid comprising a coding sequence for a selectable marker. In some embodiments, the methods further comprise selecting a host cell that expresses the selectable marker. |
FILED | Friday, September 09, 2016 |
APPL NO | 15/261727 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/902 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041356 | Lewis |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Scott D. Lewis (Vernon, Connecticut) |
ABSTRACT | The gas turbine component showerhead cooling hole layouts described herein include minimal lateral cooling hole exit diffusion on the middle showerhead cooling hole rows and interior facing sides of outer rows. In this way, rows of cooling holes may be placed close together. Stated another way, the outer showerhead cooling hole rows substantially only include lateral cooling hole exit diffusion in the direction away from the other rows to again allow the rows to be placed close together. |
FILED | Monday, June 08, 2015 |
APPL NO | 14/733686 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class F01D 9/041 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/12 (20130101) F05D 2240/30 (20130101) F05D 2240/121 (20130101) F05D 2240/303 (20130101) F05D 2260/202 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041357 | Hagan et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Benjamin F. Hagan (Manchester, Connecticut); Ryan Alan Waite (South Windsor, Connecticut); Bryan P. Dube (Columbia, Connecticut); Dominic J. Mongillo, Jr. (West Hartford, Connecticut) |
ABSTRACT | An airfoil includes a platform that has platform leading and trailing ends, lateral side faces, and inner and outer faces. An airfoil portion extends outwardly from the inner face of the platform. The airfoil portion includes airfoil leading and trailing ends and side walls that join the airfoil leading and trailing ends. The platform includes a cooling passage that has an inlet at a forward location, outlet slots at the platform trailing end, and an intermediate passage portion that extends from the inlet to the outlet slots. The intermediate passage portion includes a common manifold region that feeds the outlet slots. |
FILED | Tuesday, January 20, 2015 |
APPL NO | 14/600048 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 5/147 (20130101) F01D 5/187 (20130101) Original (OR) Class F01D 5/225 (20130101) F01D 9/041 (20130101) F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/211 (20130101) F05D 2240/12 (20130101) F05D 2240/30 (20130101) F05D 2240/81 (20130101) F05D 2260/202 (20130101) F05D 2260/22141 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041358 | Propheter-Hinckley et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut); San Quach (East Hartford, Connecticut) |
ABSTRACT | A blade for a gas turbine engine includes an airfoil having a tip with a terminal end surface and multiple squealer pockets recessed into the terminal end surface. A method of cooling a blade includes the steps of providing cooling fluid to a first squealer pocket in an airfoil tip, and providing cooling fluid to a second squealer pocket in the airfoil tip in an amount that is different than that provided to the first squealer pocket. |
FILED | Monday, April 27, 2015 |
APPL NO | 14/696601 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/20 (20130101) F01D 5/187 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041369 | Blaney et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
INVENTOR(S) | Ken F. Blaney (Middleton, New Hampshire); Brian R. Pelletier (Berwick, Maine); James N. Knapp (Sanford, Maine) |
ABSTRACT | This disclosure relates to a gas turbine engine including a blade outer air seal (BOAS) having at least one attachment hook adjacent one of a leading edge and a trailing edge thereof. The BOAS further includes at least one radial standoff axially aligned with the at least one attachment hook. |
FILED | Tuesday, August 05, 2014 |
APPL NO | 14/910899 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/08 (20130101) Original (OR) Class F01D 11/24 (20130101) F01D 21/045 (20130101) F01D 25/28 (20130101) F01D 25/246 (20130101) Non-positive-displacement Pumps F04D 29/164 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/11 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041374 | Spangler et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Brandon W. Spangler (Vernon, Connecticut); Ky H. Vu (East Hartford, Connecticut); Gina Cavallo (Watertown, Connecticut) |
ABSTRACT | A component according to an exemplary aspect of the present disclosure includes, among other things, a platform and a feed cavity that feeds a cooling fluid inside of the platform. The feed cavity includes a leg portion and a main body portion that extends from the leg portion inside of the platform. A cooling cavity is inside the platform and in fluid communication with the feed cavity. |
FILED | Monday, March 23, 2015 |
APPL NO | 14/665182 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 5/081 (20130101) F01D 5/147 (20130101) F01D 5/181 (20130101) F01D 5/186 (20130101) F01D 9/023 (20130101) F01D 25/12 (20130101) Original (OR) Class F01D 25/14 (20130101) F01D 25/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/30 (20130101) F05D 2260/202 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041767 | Thouless et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Michael Thouless (Ann Arbor, Michigan); Ellen M. Arruda (Ann Arbor, Michigan); Tanaz Rahimzadeh (Ann Arbor, Michigan); Levon Cimonian (Kentwood, Michigan); Marie Rice (Ann Arbor, Michigan) |
ABSTRACT | A tuning and mitigation system for mitigating a blast or impact event having a tuning layer assembly having an acoustic impedance chosen to tune stress waves resulting from the blast or impact to one or more specific tuned frequencies, and a dissipative layer assembly made of a viscoelastic material having a critical damping frequency that matches at least one or more specific tuned frequencies. |
FILED | Wednesday, June 15, 2016 |
APPL NO | 15/182843 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Hats; Head Coverings A42B 3/128 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/00 (20130101) B32B 5/18 (20130101) B32B 7/02 (20130101) B32B 7/12 (20130101) B32B 27/32 (20130101) B32B 27/40 (20130101) B32B 27/065 (20130101) B32B 27/302 (20130101) B32B 27/365 (20130101) B32B 2250/03 (20130101) B32B 2250/04 (20130101) B32B 2255/26 (20130101) B32B 2266/0228 (20130101) B32B 2274/00 (20130101) B32B 2307/51 (20130101) B32B 2307/56 (20130101) B32B 2307/102 (20130101) B32B 2307/302 (20130101) B32B 2307/558 (20130101) B32B 2307/732 (20130101) B32B 2571/00 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 1/04 (20130101) F41H 5/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041832 | Islam |
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FUNDED BY |
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APPLICANT(S) | OMNI MEDSCI, INC. (Ann Arbor, Michigan) |
ASSIGNEE(S) | OMNI MEDSCI, INC. (Ann Arbor, Michigan) |
INVENTOR(S) | Mohammed N. Islam (Ann Arbor, Michigan) |
ABSTRACT | A super continuum light source includes an input light source having semiconductor diodes generating an input beam having a wavelength shorter than 2.5 microns. Optical amplifiers receive the input beam and form an amplified optical beam having a spectral width. The optical amplifiers may include a cladding-pumped fiber amplifier doped with rare-earth materials. A nonlinear element may include mid-infrared fibers to receive the amplified optical beam and to broaden the spectral width of the received amplified optical beam to 100 nm or more through a nonlinear effect forming an output beam, wherein the output beam is pulsed. At least a portion of the output beam is in a mid-infrared wavelength range between 2 microns and 5 microns and at least a portion of the one or more mid-infrared fibers comprises a ZBLAN fluoride fiber coupled to a chalcogenide fiber. |
FILED | Friday, July 28, 2017 |
APPL NO | 15/662527 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/108 (20130101) Original (OR) Class G01J 3/0218 (20130101) G01J 3/0245 (20130101) G01J 2003/102 (20130101) G01J 2003/423 (20130101) Optical Elements, Systems, or Apparatus G02B 6/29349 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 2001/3528 (20130101) G02F 2202/32 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/302 (20130101) H01S 3/1024 (20130101) H01S 3/06725 (20130101) H01S 3/06754 (20130101) H01S 3/094007 (20130101) H01S 3/094069 (20130101) H01S 3/094076 (20130101) H01S 5/0064 (20130101) H01S 5/0085 (20130101) H01S 5/0092 (20130101) H01S 5/146 (20130101) H01S 5/1092 (20130101) H01S 5/4012 (20130101) H01S 2301/085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041959 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | BANYAN BIOMARKERS, INC. (Alachua, Florida) |
ASSIGNEE(S) | Banyan Biomarkers, Inc. (Alachua, Florida); The United States of America, as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Kevin Ka-Wang Wang (Gainesville, Florida); Zhiqun Zhang (Auburndale, Massachusetts); Ming-Cheng Liu (Plano, Texas); Ronald L. Hayes (Alachua, Florida); Jitendra Ramanlal Dave (Gaithersburg, Maryland) |
ABSTRACT | Processes and materials are provided for the detection, diagnosis, or determination of the severity of a neurological injury or condition, including traumatic brain injury, multiple-organ injury, stroke, Alzeimer's disease, Parkinson disease and Chronic Traumatic Encephalopathy (CTE). The processes and materials include biomarkers detected or measured in a biological sample such as whole blood, serum, plasma, or CSF. Such biomarkers include Tau and GFAP proteins, their proteolytic breakdown products, brain specific or enriched micro-RNA, and brain specific or enriched protein directed autoantibodies. The processes and materials are operable to detect the presence of absence of acute, subacute or chronic brain injuries and predict outcome for the brain injury. |
FILED | Tuesday, December 27, 2016 |
APPL NO | 15/391755 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/5308 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 2800/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041971 | Grinolds et al. |
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FUNDED BY |
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APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
INVENTOR(S) | Michael S. Grinolds (Somerville, Massachusetts); Sungkun Hong (Vienna, Austria); Patrick Maletinsky (Basel, Switzerland); Amir Yacoby (Newton, Massachusetts) |
ABSTRACT | A sensing probe may be formed of a diamond material comprising one or more spin defects that are configured to emit fluorescent light and are located no more than 50 nm from a sensing surface of the sensing probe. The sensing probe may include an optical outcoupling structure formed by the diamond material and configured to optically guide the fluorescent light toward an output end of the optical outcoupling structure. An optical detector may detect the fluorescent light that is emitted from the spin defects and that exits through the output end of the optical outcoupling structure after being optically guided therethrough. A mounting system may hold the sensing probe and control a distance between the sensing surface of the sensing probe and a surface of a sample while permitting relative motion between the sensing surface and the sample surface. |
FILED | Tuesday, August 20, 2013 |
APPL NO | 14/423123 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/645 (20130101) G01N 24/10 (20130101) G01N 2201/10 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/025 (20130101) G01Q 60/08 (20130101) G01Q 60/38 (20130101) G01Q 60/54 (20130101) G01Q 70/14 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) G01R 33/032 (20130101) G01R 33/60 (20130101) G01R 33/323 (20130101) G01R 33/1284 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042067 | Ruffa |
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FUNDED BY |
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APPLICANT(S) | Anthony A Ruffa (Hope Valley, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Anthony A Ruffa (Hope Valley, Rhode Island) |
ABSTRACT | A safety system and method of use is provided for a tow cable handling system. In use, the cable is from a winch and onto a sheave where a cable tension surge is transmitted to a meter and onto a software element. The software of a controller determines torque needed from a motor to increase winch speed to unreel cable to relieve the surge but not too much that the cable will unreel off the winch. Once the surge concludes, the motor reverses and decreases speed of the winch. If the tension surge is transient, then the motor can increase the winch speed and then slow down the winch before the cable completely unreels. The sheave is suspended by a spring and a dashpot for an over-damped response to increase the time for the winch to speed up to an acceptable speed. |
FILED | Monday, September 25, 2017 |
APPL NO | 15/713890 |
ART UNIT | 3654 — Material and Article Handling |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/66 (20130101) Cranes; Load-engaging Elements or Devices for Cranes, Capstans, Winches, or Tackles B66C 13/02 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/3843 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042091 | Kildishev et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
INVENTOR(S) | Alexander Kildishev (West Lafayette, Indiana); Satoshi Ishii (Hyogo, Japan); Vladimir Shalaev (West Layfayette, Indiana) |
ABSTRACT | A planar optical device, comprised of sets of nanometer-scale holes milled into a thin metal or ceramic film of subwavelength thickness serves to form arbitrary waveform of light. The holes form a pattern, preferrably rings, of various sizes in order to achieve a given phase front of light due to photonic effect. When designed as a lens, the device focuses incident light into a tight focal spot. In symmetric design, the focusing property of the device does not depend on the incident polarization angle. The lens can be manufactured based on high-throughput fabrication methods and easily integrated with a chip or placed at the end of an optical fiber. |
FILED | Thursday, September 26, 2013 |
APPL NO | 14/431544 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/005 (20130101) G02B 3/08 (20130101) Original (OR) Class G02B 3/0087 (20130101) G02B 5/008 (20130101) G02B 6/262 (20130101) G02B 6/1225 (20130101) G02B 6/1226 (20130101) G02B 2207/101 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 1/397 (20130101) G02F 1/2255 (20130101) G02F 2203/06 (20130101) G02F 2203/13 (20130101) G02F 2203/50 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/888 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042147 | Olsen |
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FUNDED BY |
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APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Randall B. Olsen (Carlsbad, California) |
ABSTRACT | A glass concentrator mirror assembly and a method for making same. A glass concentrator mirror assembly is configured to reflect sunlight to a receiver in a reflector assembly. The glass concentrator mirror assembly has at least one glass mirror. The at least one glass mirror has a reflective side and a back side. The glass concentrator mirror assembly also has a parabola-forming frame structure for the at least one glass mirror. The parabola-forming frame structure includes a sternum that is fixedly fastened to a spine with the at least one glass mirror therebetween. The parabola-forming frame structure facilitates a substantially parabolic curvature of the at least one glass mirror. The parabola-forming frame structure provides a substantially uniform force along a line of contact between the sternum and the at least one glass mirror. |
FILED | Wednesday, December 14, 2016 |
APPL NO | 15/379247 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/183 (20130101) G02B 19/0023 (20130101) G02B 19/0042 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042177 | Pitera et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretry of the Army (Washington, District of Columbia) |
INVENTOR(S) | Thomas Pitera (Fair Lawn, New Jersey); Joseph Petillo (Kenvil, New Jersey); James Hitscherich (Mount Arlington, New Jersey) |
ABSTRACT | An aiming reticle comprising two primary characteristic feature sets consisting of a grid system and auxiliary crosshairs. The grid comprises horizontal crosshairs that are perpendicular to but do not intersect with a primary vertical crosshair. Omission of markings along the primary vertical crosshair and non-intersecting horizontal crosshairs provides improved target visibility along the vicinity of the primary vertical crosshair. The grid horizontal crosshairs are marked with intersecting major stadia lines, preferably at unit spatial intervals. The grid system further comprises self-contained crosses of predetermined size, within the space enclosed by the grid major stadia lines and grid horizontal crosshair separations to provide sub-unit reference in the vertical and horizontal reference. |
FILED | Monday, September 26, 2016 |
APPL NO | 15/276012 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Weapon Sights; Aiming F41G 1/38 (20130101) Optical Elements, Systems, or Apparatus G02B 27/32 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042511 | Roe et al. |
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FUNDED BY |
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APPLICANT(S) | Marvin W Roe (Slidell, Louisiana); Geary J Layne (Boulder, Colorado) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Marvin W Roe (Slidell, Louisiana); Geary J Layne (Boulder, Colorado) |
ABSTRACT | A user control is provided for use with a multidimensional dataset that allows a user to graphically set the bounds for one or more of the dimensions of data selected from the dataset. The graphical user control includes a wireframe cube representing the extent of data in the dataset and a selector box within the data cube. A user can indicate a selected perspective and orientation of the data by selecting a portion of an edge of the selector box, and a visual indication of the selected perspective and orientation is provided. The user further can select a desired portion of the data by changing a size and/or a position of the selector box within the data cube. The graphical user control further includes a visual indicator representing the fourth dimension of the dataset and one or more navigation buttons. |
FILED | Thursday, July 03, 2014 |
APPL NO | 14/323715 |
ART UNIT | 2173 — Graphical User Interface and Document Processing |
CURRENT CPC | Electric Digital Data Processing G06F 3/04815 (20130101) Original (OR) Class G06F 3/04847 (20130101) G06F 17/30592 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042644 | Satpathy et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Sudhir K. Satpathy (Hillsboro, Oregon); Sanu K. Mathew (Hillsboro, Oregon); Vinodh Gopal (Westborough, Massachusetts); James D. Guilford (Northborough, Massachusetts) |
ABSTRACT | An apparatus and method for performing parallel decoding of prefix codes such as Huffman codes. For example, one embodiment of an apparatus comprises: a first decompression module to perform a non-speculative decompression of a first portion of a prefix code payload comprising a first plurality of symbols; and a second decompression module to perform speculative decompression of a second portion of the prefix code payload comprising a second plurality of symbols concurrently with the non-speculative decompression performed by the first compression module. |
FILED | Tuesday, December 06, 2016 |
APPL NO | 15/371091 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Electric Digital Data Processing G06F 9/3016 (20130101) G06F 9/30021 (20130101) G06F 9/30156 (20130101) G06F 9/30185 (20130101) Original (OR) Class Coding; Decoding; Code Conversion in General H03M 7/4037 (20130101) H03M 7/6005 (20130101) H03M 7/6023 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043110 | Andreopoulos et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Alexander Andreopoulos (San Jose, California); Rathinakumar Appuswamy (San Jose, California); Pallab Datta (San Jose, California); Steven K. Esser (San Jose, California); Dharmendra S. Modha (San Jose, California) |
ABSTRACT | Embodiments of the invention provide a method for scene understanding based on a sequence of image frames. The method comprises converting each pixel of each image frame to neural spikes, and extracting features from the sequence of image frames by processing neural spikes corresponding to pixels of the sequence of image frames. The method further comprises encoding the extracted features as neural spikes, and classifying the extracted features. |
FILED | Wednesday, October 19, 2016 |
APPL NO | 15/298137 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/46 (20130101) G06K 9/52 (20130101) G06K 9/66 (20130101) G06K 9/00718 (20130101) G06K 9/00986 (20130101) G06K 9/4623 (20130101) G06K 9/4652 (20130101) G06K 9/4661 (20130101) G06K 9/4671 (20130101) G06K 9/4676 (20130101) G06K 9/6256 (20130101) Original (OR) Class G06K 9/6267 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0635 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 2207/10016 (20130101) G06T 2207/20081 (20130101) Pictorial Communication, e.g Television H04N 9/67 (20130101) H04N 19/136 (20141101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043241 | Andreopoulos et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Alexander Andreopoulos (San Jose, California); Daniel F. Gruhl (San Jose, California); Michael Karasick (White Plains, New York); Dharmendra S. Modha (San Jose, California) |
ABSTRACT | One or more embodiments provide a neurosynaptic circuit that includes multiple neurosynaptic core circuits that: perform image sharpening by converting a source image to a sharpened destination image by: taking as input a sequence of image frames of a video with one or more channels per frame, and representing the intensity of each pixel of each channel of each frame as neural spikes, and processing neural spike representations of the sharpened destination image for outputting a spike representation of the sharpened destination image. |
FILED | Tuesday, December 19, 2017 |
APPL NO | 15/847509 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/4604 (20130101) Image Data Processing or Generation, in General G06T 3/4046 (20130101) Original (OR) Class G06T 5/006 (20130101) G06T 2207/20084 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043248 | Andreopoulos et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Alexander Andreopoulos (San Jose, California); Daniel F. Gruhl (San Jose, California); Michael Karasick (White Plains, New York); Dharmendra S. Modha (San Jose, California) |
ABSTRACT | One or more embodiments provide a system and circuit for image distortion correction. The system includes neurosynaptic core circuits that: receive a set of inputs comprising image dimensions and pixel distortion coefficients for at least one image frame via at least one input core circuit, map each distorted pixel to zero or more undistorted pixels by processing the set of inputs corresponding to each pixel of the at least one image frame by the at least one input core circuit, and route corresponding pixel intensity values of each distorted pixel to output undistorted pixels for each image frame via at least one output core circuit. |
FILED | Monday, April 24, 2017 |
APPL NO | 15/495472 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 5/006 (20130101) Original (OR) Class G06T 2207/20172 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043565 | Fox et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Glen Richard Fox (Colorado Springs, Colorado); Jeffrey S. Pulskamp (Fulton, Maryland); Ronald G. Polcawich (Derwood, Maryland) |
ABSTRACT | A ferroelectric mechanical memory structure comprising a substrate, a MEMS switch element movable between a first position and at least one second position, the MEMS switch element comprising first and second electrodes, a layer of ferroelectric material positioned between the first and second electrodes so that upon application of voltage between the first and second electrodes the MEMS switch element moves between the first position and the second position, and a switch contact which contacts the first electrode only when the MEMS switch element is in the first position, wherein the ferroelectric material is selected so that the remanent strain within the layer of ferroelectric material is controlled by the history of the voltage potential applied to the ferroelectric material by the first and second electrodes, and wherein the remanent strain is sufficient to retain the MEMS switch element in the first or second position upon removal of the voltage. |
FILED | Monday, April 18, 2016 |
APPL NO | 15/131881 |
ART UNIT | 2897 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 11/22 (20130101) G11C 11/50 (20130101) G11C 11/221 (20130101) Original (OR) Class G11C 23/00 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 2057/006 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/094 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043607 | Deligianni et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Hariklia Deligianni (Alpine, New Jersey); William J. Gallagher (Ardsley, New York); Yu Luo (Hopewell Junction, New York); Lubomyr T. Romankiw (Briancliff Manor, New York); Joonah Yoon (Poughkeepsie, New York) |
ABSTRACT | Present disclosure relates to magnetic materials, chips having magnetic materials, and methods of forming magnetic materials. In certain embodiments, magnetic materials may include a seed layer, and a cobalt-based alloy formed on seed layer. The seed layer may include copper, cobalt, nickel, platinum, palladium, ruthenium, iron, nickel alloy, cobalt-iron-boron alloy, nickel-iron alloy, and any combination of these materials. In certain embodiments, the chip may include one or more on-chip magnetic structures. Each on-chip magnetic structure may include a seed layer, and a cobalt-based alloy formed on seed layer. In certain embodiments, method may include: placing a seed layer in an aqueous electroless plating bath to form a cobalt-based alloy on seed layer. In certain embodiments, the aqueous electroless plating bath may include sodium tetraborate, an alkali metal tartrate, ammonium sulfate, cobalt sulfate, ferric ammonium sulfate and sodium borohydride and has a pH between about 9 to about 13. |
FILED | Monday, May 02, 2016 |
APPL NO | 15/143992 |
ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/50 (20130101) C23C 18/168 (20130101) C23C 18/1637 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/15308 (20130101) Original (OR) Class H01F 1/15333 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043687 | Bert et al. |
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FUNDED BY |
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APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
ASSIGNEE(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
INVENTOR(S) | Julie A. Bert (East Palo Alto, California); David K. Biegelsen (Portola Valley, California); Sourobh Raychaudhuri (Mountain View, California) |
ABSTRACT | An apparatus including a bumped electrode array and a method of fabricating a bumped electrode array is disclosed. The method includes providing a substrate for the electrode array. The method also includes disposing a plurality of non-planar structures including electrodes above the substrate of the electrode array. The method further includes disposing a dielectric layer above the plurality of non-planar structures having a defined radius of curvature. |
FILED | Tuesday, December 27, 2016 |
APPL NO | 15/391140 |
ART UNIT | 2822 — Semiconductors/Memory |
CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 3/004 (20130101) B81C 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/68 (20130101) H01L 21/6835 (20130101) H01L 21/6875 (20130101) H01L 21/67121 (20130101) Original (OR) Class H01L 24/95 (20130101) H01L 25/50 (20130101) H01L 25/0655 (20130101) H01L 2221/68368 (20130101) H01L 2224/95085 (20130101) H01L 2224/95133 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043765 | Cabral, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Cyril Cabral, Jr. (Yorktown Heights, New York); Kenneth P. Rodbell (Sandy Hook, Connecticut) |
ABSTRACT | An integrated circuit structure and formation thereof. The integrated circuit structure includes a substrate and a front-end-of-the-line (FEOL) portion. The FEOL portion rests on top of and in contact with the substrate. The integrated circuit structure includes a memory level portion. The memory level portion rests on top of and in contact with the FEOL portion. The integrated circuit structure includes a back-end-of-the-line (BEOL) portion. The BEOL portion rests on top of and in contact with the memory level portion. The integrated circuit structure includes a multiple layer that includes one or more pairs of reactive materials. The multiple layer is one or more of: i) on top of the BEOL portion; ii) within the BEOL portion; iii) within the memory level portion; iv) within the FEOL portion; v) embedded in the substrate; and vi) on bottom of a thinned substrate. |
FILED | Monday, October 02, 2017 |
APPL NO | 15/722219 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76892 (20130101) H01L 23/573 (20130101) Original (OR) Class H01L 27/2463 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043925 | Ram et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Rajeev Jagga Ram (Arlington, Massachusetts); Jason Scott Orcutt (Katonah, New York); Huaiyu Meng (Medford, Massachusetts); Amir H. Atabaki (North Quincy, Massachusetts) |
ABSTRACT | Guided-wave photodetectors based on absorption of infrared photons by mid-bandgap states in non-crystal semiconductors. In one example, a resonant guided-wave photodetector is fabricated based on a polysilicon layer used for the transistor gate in a SOI CMOS process without any change to the foundry process flow (‘zero-change’ CMOS). Mid-bandgap defect states in the polysilicon absorb infrared photons. Through a combination of doping mask layers, a lateral p-n junction is formed in the polysilicon, and a bias voltage applied across the junction creates a sufficiently strong electric field to enable efficient photo-generated carrier extraction and high-speed operation. An example device has a responsivity of more than 0.14 A/W from 1300 to 1600 nm, a 10 GHz bandwidth, and 80 nA dark current at 15 V reverse bias. |
FILED | Monday, August 29, 2016 |
APPL NO | 15/250594 |
ART UNIT | 2891 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/1443 (20130101) H01L 31/103 (20130101) H01L 31/02327 (20130101) Original (OR) Class H01L 31/03682 (20130101) H01L 31/035281 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/546 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043939 | Foos et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Edward E. Foos (Alexandria, Virginia); Troy K. Townsend (Alexandria, Virginia) |
ABSTRACT | A technique is described depositing a new formula of indium and tin salt solutions as a precursor to form a solid transparent indium tin oxide (ITO) film on non-conductive solid substrates. The utilization of this new composition of matter prompted the discovery of a method for preparing the first top-to-bottom completely solution processed solar cell. The specific patterning of the liquid-processed ITO precursor solution and the subsequent layers of a solar cell outlined here also demonstrate a unique way to connect solution processed (as opposed to deposited using vacuum techniques) solar cells in series and in parallel. Also disclosed are related methods for zinc tin oxide (ZTO), indium oxide (IO), indium zinc oxide (IZO), cadmium tin oxide (CTO), aluminum zinc oxide (AZO), and zinc oxide (ZO). |
FILED | Thursday, September 15, 2016 |
APPL NO | 15/266878 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/073 (20130101) H01L 31/0504 (20130101) H01L 31/0512 (20130101) H01L 31/1884 (20130101) Original (OR) Class H01L 31/02327 (20130101) H01L 31/022475 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043964 | Toonen et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Ryan C. Toonen (Belcamp, Maryland); Mathew P. Ivill (Havre de Grace, Maryland); Melanie W. Cole (Churchville, Maryland) |
ABSTRACT | A pyroelectric device having a substrate and a first electrode overlying at least a portion of the substrate. A plurality of spaced apart nanometer sized pyroelectric elements are electrically connected to and extending outwardly from the first electrode so that each element forms a single domain. A dielectric material is deposited in the space between the individual elements and a second electrode spaced apart from said first electrode is electrically connected to said pyroelectric elements. |
FILED | Friday, May 26, 2017 |
APPL NO | 15/606091 |
ART UNIT | 2898 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/16 (20130101) H01L 29/93 (20130101) H01L 29/0653 (20130101) H01L 29/0676 (20130101) H01L 29/66174 (20130101) H01L 37/02 (20130101) H01L 37/025 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043993 | Arango et al. |
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FUNDED BY |
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APPLICANT(S) | Alexi Arango (Somerville, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts); David Oertel (Hamilton, Ohio); Moungi G. Bawendi (Cambridge, Massachusetts) |
ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Alexi Arango (Somerville, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts); David Oertel (Hamilton, Ohio); Moungi G. Bawendi (Cambridge, Massachusetts) |
ABSTRACT | An electro-optical device can include a plurality of semiconductor nanocrystals. In some circumstances, the device can omit an electron transporting layer. |
FILED | Monday, June 25, 2007 |
APPL NO | 11/768015 |
ART UNIT | 1757 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0037 (20130101) H01L 51/426 (20130101) Original (OR) Class H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044057 | Wachsman et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation Inc. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
INVENTOR(S) | Eric D. Wachsman (Fulton, Maryland); Sean Robert Bishop (Waltham, Massachusetts) |
ABSTRACT | A fuel cell anode comprises a porous ceramic molten metal composite of a metal or metal alloy, for example, tin or a tin alloy, infused in a ceramic where the metal is liquid at the temperatures of an operational solid oxide fuel cell, exhibiting high oxygen ion mobility. The anode can be employed in a SOFC with a thin electrolyte that can be a ceramic of the same or similar composition to that infused with the liquid metal of the porous ceramic molten metal composite anode. The thicknesses of the electrolyte can be reduced to a minimum that allows greater efficiencies of the SOFC thereby constructed. |
FILED | Tuesday, October 20, 2015 |
APPL NO | 14/887909 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8621 (20130101) H01M 4/8652 (20130101) H01M 4/9025 (20130101) H01M 4/9066 (20130101) H01M 8/126 (20130101) H01M 8/1213 (20130101) Original (OR) Class H01M 2008/1293 (20130101) H01M 2300/0074 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044062 | Horowitz et al. |
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FUNDED BY |
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APPLICANT(S) | Tufts University (Boston, Massachusetts) |
ASSIGNEE(S) | Tufts University (Boston, Massachusetts) |
INVENTOR(S) | Ariel Horowitz (Somerville, Massachusetts); Matthew Panzer (Somerville, Massachusetts) |
ABSTRACT | An ionic material that contains a crosslinked polydimethylsiloxane network and an ionic liquid and, optionally, a lithium salt. Also disclosed are a methods of preparing the above-described ionic material, as well as a battery and a capacitor each including the ionic material as an electrolyte. |
FILED | Monday, December 15, 2014 |
APPL NO | 15/103348 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/54 (20130101) H01G 11/56 (20130101) H01G 11/58 (20130101) H01G 11/62 (20130101) H01G 11/84 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0022 (20130101) H01M 2300/0045 (20130101) H01M 2300/0085 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044085 | Ma et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Zhenqiang Ma (Middleton, Wisconsin); Yei Hwan Jung (Madison, Wisconsin); Juhwan Lee (Madison, Wisconsin); Shaoqin Gong (Middleton, Wisconsin) |
ABSTRACT | Stretchable high frequency transmission lines and high-frequency filters comprising the transmission lines are provided. The transmission lines provide low power loss, even at microwave and millimeter wave frequencies. The transmission lines are thin and flexible and can be stretched without a significant degradation of their scattering parameters. As a result, the transmission lines have applications as interconnects in stretchable and flexible integrated circuits (IC) and circuit device components, such as flexible transistors and flexible diodes. |
FILED | Thursday, April 14, 2016 |
APPL NO | 15/098636 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/08 (20130101) Original (OR) Class H01P 11/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044107 | Elliot et al. |
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FUNDED BY |
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APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
INVENTOR(S) | Paul Gordon Elliot (Acton, Massachusetts); Eddie Nelson Rosario (Methuen, Massachusetts) |
ABSTRACT | A multi-use antenna system that can be used in, for example, integrated communications and navigation capability is provided. In an embodiment, an antenna system is provided. The antenna system includes a first antenna having a plurality of radiating elements substantially wrapped around an axis and a second antenna located within the first antenna. The first and second antennas are coupled to the same ground plane and are configured to operate in different frequency bands. |
FILED | Thursday, March 02, 2017 |
APPL NO | 15/447635 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 11/08 (20130101) Original (OR) Class H01Q 21/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044108 | Jablon et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Allan R. Jablon (Ellicott City, Maryland); Gerald F. Ricciardi (Mount Airy, Maryland) |
ABSTRACT | Example apparatuses and methods relating to antennas are provided. An example apparatus in the form of an antenna assembly includes a first conductor structurally formed into a plurality of first conductor structural waves and a second conductor structurally formed into a plurality of second conductor structural waves. The first conductor and second conductor may be helically wound to form a bifilar helix structure having a proximal end and a distal end. The first conductor and the second conductor may be operatively coupled at the proximal end of the bifilar helix structure to form a signal feed point, and the first conductor and the second conductor are operatively coupled at the distal end of the bifilar helix structure to form a load point. |
FILED | Thursday, November 10, 2016 |
APPL NO | 15/347902 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/362 (20130101) H01Q 11/083 (20130101) Original (OR) Class H01Q 19/025 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044227 | Chappell et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | William J. Chappell (Lafayette, Indiana); Dohyuk Ha (Lafayette, Indiana); Henry Mei (West Lafayette, Indiana); Pedro P. Irazoqui (West Lafayette, Indiana) |
ABSTRACT | A wireless power transfer system is disclosed. The system includes a first resonator having a first resonant frequency ωo1, a half power bandwidth Δω1, and an unloaded quality factor Qo1=ωo1/Δω1 coupled through a first coupling circuit to a power source, a second resonator having a second resonant frequency ωo2, a half power bandwidth Δω2, and an unloaded quality factor Qo2=ωo2/Δω2 coupled through a second coupling circuit to a load, the first resonator disposed a distance away from the second resonator, wherein the distance is smaller than the first and second resonant wavelengths, the first and second coupling circuits are configured so that up to a maximum achievable power transfer efficiency between the first and second resonators can be achieved, wherein Qo1 and Qo2 can be less than 100. |
FILED | Tuesday, June 02, 2015 |
APPL NO | 14/728976 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 38/14 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 17/00 (20130101) H02J 50/12 (20160201) Original (OR) Class H02J 50/50 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044626 | Underwood et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Keith Underwood (Powell, Tennessee); Charles Giefer (Seattle, Washington); Mark Debbage (Santa Clara, California); Karl P. Brummel (Chicago, Illinois); Nathan Miller (Seattle, Washington); Bruce Pirie (Renton, Washington) |
ABSTRACT | In an embodiment, an out-of-order, reliable, end-to-end protocol is provided that can enable direct user-level data placement and atomic operations between nodes of a multi-node network. The protocol may be optimized for low-loss environments such as High Performance Computing (HPC) applications, and may enable loss detection and de-duplication of packets through the use of a robust window state manager at a target node. A multi-node network implementing the protocol may have increased system reliability, packet throughput, and increased tolerance for adaptively routed traffic, while still allowing atomic operations to be idempotently applied directly to a user memory location. |
FILED | Thursday, December 24, 2015 |
APPL NO | 14/757993 |
ART UNIT | 2476 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/187 (20130101) H04L 1/1621 (20130101) H04L 1/1635 (20130101) H04L 1/1832 (20130101) H04L 47/18 (20130101) H04L 47/27 (20130101) H04L 47/34 (20130101) Original (OR) Class H04L 47/58 (20130101) H04L 69/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044748 | Dagon et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia); Georgia Institute of Technology (Atlanta, Georgia) |
INVENTOR(S) | David Dagon (Tampa, Florida); Nick Feamster (Atlanta, Georgia); Wenke Lee (Atlanta, Georgia); Robert Edmonds (Woodstock, Georgia); Richard Lipton (Atlanta, Georgia); Anirudh Ramachandran (Atlanta, Georgia) |
ABSTRACT | A system and method for detecting a first network of compromised computers in a second network of computers, comprising: collecting Domain Name System (DNS) data for the second network; examining the collected data relative to DNS data from known comprised and/or uncompromised computers in the second network; and determining the existence of the first network and/or the identity of compromised computers in the second network based on the examination. |
FILED | Tuesday, February 09, 2016 |
APPL NO | 15/019272 |
ART UNIT | 2438 — Cryptography and Security |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 29/12066 (20130101) H04L 29/12301 (20130101) H04L 61/1511 (20130101) H04L 61/2076 (20130101) H04L 63/1425 (20130101) H04L 63/1441 (20130101) Original (OR) Class H04L 63/1491 (20130101) H04L 2463/144 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 10039999 | Siepmann et al. |
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FUNDED BY |
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APPLICANT(S) | Joern Ilja Siepmann (Hastings, Minnesota); Peng Bai (Minneapolis, Minnesota); Michael Tsapatsis (Minneapolis, Minnesota) |
ASSIGNEE(S) | |
INVENTOR(S) | Joern Ilja Siepmann (Hastings, Minnesota); Peng Bai (Minneapolis, Minnesota); Michael Tsapatsis (Minneapolis, Minnesota) |
ABSTRACT | A process for separating ethanol from a mixture including ethanol and water comprises contacting the mixture with a sorbent or membrane including one or more zeolites having a high adsorption selectivity toward ethanol over water, wherein at least a fraction of the ethanol from the mixture is adsorbed by the sorbent or membrane and an unadsorbed portion of the mixture forms a raffinate having a lower concentration of ethanol than the mixture. The process further includes releasing adsorbed ethanol from the sorbent or membrane as a retentate or a permeant to produce an ethanol extract having a higher concentration of ethanol than the mixture. |
FILED | Wednesday, July 22, 2015 |
APPL NO | 15/327722 |
ART UNIT | 1671 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Separation B01D 15/08 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/18 (20130101) B01J 20/28033 (20130101) Acyclic or Carbocyclic Compounds C07C 29/76 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040057 | Seong et al. |
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FUNDED BY |
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APPLICANT(S) | Hee Je Seong (Aurora, Illinois); Seungmok Choi (Naperville, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Hee Je Seong (Aurora, Illinois); Seungmok Choi (Naperville, Illinois) |
ABSTRACT | The invention provides a method for oxidizing chemical, the method having the steps of contacting soot to a catalyst defining a plurality of flat substrates forming a monolith, wherein any one of the substrates has a thickness no greater than 30 nm. Also provided is a catalyst for oxidizing chemical, the catalyst have a morphology having layered plates, wherein any plate is no more than 30 nm thick. The invention also provides a method for producing an oxidation catalyst, the method having the steps of combining a cobalt compound with a potassium compound to create a solution; contacting the solution with a reducing agent for a time and at a temperature sufficient to oxidize the cobalt compound and form a precipitate of the oxidized cobalt compound; filtering the precipitate; and calcining the filtered precipitate. |
FILED | Thursday, July 06, 2017 |
APPL NO | 15/643108 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/944 (20130101) B01D 2255/2022 (20130101) B01D 2255/2065 (20130101) B01D 2255/2073 (20130101) B01D 2255/20746 (20130101) B01D 2255/20776 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/75 (20130101) B01J 23/78 (20130101) B01J 23/83 (20130101) B01J 23/888 (20130101) B01J 23/8892 (20130101) Original (OR) Class B01J 35/04 (20130101) B01J 37/04 (20130101) B01J 37/08 (20130101) B01J 37/009 (20130101) B01J 37/031 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/2842 (20130101) F01N 2370/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040113 | Branson et al. |
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FUNDED BY |
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APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
INVENTOR(S) | Donald Branson (Kansas City, Missouri); Kevin Troyer (Kansas City, Missouri) |
ABSTRACT | A self-aligning swaging punch is provided for adjoining together a pin and a workpiece having a pinhole. The swaging punch comprises a shaft and a tip having an open-ended cavity. The shaft transfers an axial force from a press or hammer to the tip. The tip transfers the axial force from the shaft to a top surface of the workpiece near the pinhole. The tip may be spherical in shape for evenly deforming the workpiece near the upper edge of the pinhole. The open-ended cavity receives the pin therein and allows the pin to extend at least partially into the open-ended cavity while the tip contacts the workpiece. The open-ended cavity also ensures that the swaging punch is aligned with the pinhole and perpendicular to the surface of the workpiece when the pin is inserted into the pinhole such that the workpiece evenly deforms and presses against the pin. |
FILED | Wednesday, September 23, 2015 |
APPL NO | 14/862990 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Making Forged or Pressed Metal Products, e.g Horse-shoes, Rivets, Bolts or Wheels B21K 25/00 (20130101) Original (OR) Class Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 11/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49908 (20150115) Y10T 29/49925 (20150115) Y10T 29/49936 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041060 | Venter et al. |
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FUNDED BY |
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APPLICANT(S) | J. Craig Venter (La Jolla, California); Hamilton O. Smith (San Diego, California); Clyde A. Hutchison, III (La Jolla, California); Daniel G. Gibson (Crofton, Maryland) |
ASSIGNEE(S) | Synthetic Genomics, Inc. (La Jolla, California) |
INVENTOR(S) | J. Craig Venter (La Jolla, California); Hamilton O. Smith (San Diego, California); Clyde A. Hutchison, III (La Jolla, California); Daniel G. Gibson (Crofton, Maryland) |
ABSTRACT | Methods are provided for constructing a synthetic genome, comprising generating and assembling nucleic acid cassettes comprising portions of the genome, wherein at least one of the nucleic acid cassettes is constructed from nucleic acid components that have been chemically synthesized, or from copies of the chemically synthesized nucleic acid components. In one embodiment, the entire synthetic genome is constructed from nucleic acid components that have been chemically synthesized, or from copies of the chemically synthesized nucleic acid components. Rational methods may be used to design the synthetic genome (e.g., to establish a minimal genome and/or to optimize the function of genes within a genome, such as by mutating or rearranging the order of the genes). Synthetic genomes of the invention may be introduced into vesicles (e.g., bacterial cells from which part or all of the resident genome has been removed, or synthetic vesicles) to generate synthetic cells. Synthetic genomes or synthetic cells may be used for a variety of purposes, including the generation of synthetic fuels, such as hydrogen or ethanol. |
FILED | Wednesday, December 06, 2006 |
APPL NO | 11/635355 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) Original (OR) Class C12N 15/66 (20130101) C12N 15/1093 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041065 | Raman et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Srivatsan Raman (Arlington, Massachusetts); Noah D. Taylor (Boston, Massachusetts); George M. Church (Brookline, Massachusetts) |
ABSTRACT | Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided. |
FILED | Wednesday, June 21, 2017 |
APPL NO | 15/628690 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1058 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041101 | Quinlan et al. |
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FUNDED BY |
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APPLICANT(S) | Novozymes, Inc. (Davis, California) |
ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
INVENTOR(S) | Jason Quinlan (Woodland, California); Feng Xu (Davis, California); Matthew Sweeney (Sacramento, California) |
ABSTRACT | The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a heterocyclic compound. The present invention also relates to methods of using the compositions. |
FILED | Monday, June 27, 2016 |
APPL NO | 15/193434 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 9/2437 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) C12P 5/02 (20130101) C12P 5/026 (20130101) C12P 7/10 (20130101) C12P 7/26 (20130101) C12P 7/28 (20130101) C12P 7/40 (20130101) C12P 13/04 (20130101) C12P 19/02 (20130101) C12P 19/12 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2201/00 (20130101) C12P 2203/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041171 | She et al. |
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FUNDED BY |
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APPLICANT(S) | Delavan Inc (West Des Moines, Iowa) |
ASSIGNEE(S) | Delavan Inc. (West Des Moines, Iowa) |
INVENTOR(S) | Ying She (East Hartford, Connecticut); Michael A. Klecka (Vernon, Connecticut); Tahany I. El-Wardany (Bloomfield, Connecticut); Anais Espinal (West Harford, Connecticut); Wayde R. Schmidt (Pomfret Center, Connecticut); Sameh Dardona (South Windsor, Connecticut) |
ABSTRACT | A particulate for an additive manufacturing technique includes metallic particulate bodies with exterior surfaces bearing a polymeric coating. The polymeric coating is conformally disposed over the exterior surface that prevents the underlying metallic body from oxidation upon exposure to the ambient environment by isolating the metallic particulate bodies from the ambient environment. Feedstock materials for additive manufacturing techniques, and methods of making such feedstock, are also disclosed. |
FILED | Monday, August 10, 2015 |
APPL NO | 14/822713 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/00 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0062 (20130101) B22F 1/0062 (20130101) B22F 3/008 (20130101) B22F 9/22 (20130101) B22F 9/22 (20130101) B22F 2201/01 (20130101) B22F 2201/10 (20130101) B22F 2202/17 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 183/04 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/12 (20130101) C23C 16/442 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041179 | Kumta et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Karan Sandeep Kadakia (Pittsburgh, Pennsylvania); Moni Kanchan Datta (Pittsburgh, Pennsylvania); Oleg Velikokhatnyi (Pittsburgh, Pennsylvania); Prashanth Jampani Hanumantha (Pittsburgh, Pennsylvania) |
ABSTRACT | The invention provides electro-catalyst compositions for an anode electrode of an acid mediated proton exchange membrane-based water electrolysis system. The compositions include a noble metal component selected from the group consisting of iridium oxide, ruthenium oxide, rhenium oxide and mixtures thereof, and a non-noble metal component selected from the group consisting of tantalum oxide, tin oxide, niobium oxide, titanium oxide, tungsten oxide, molybdenum oxide, yttrium oxide, scandium oxide, cooper oxide, zirconium oxide, nickel oxide and mixtures thereof. Further, the non-noble metal component can include a dopant. The dopant can be at least one element selected from Groups III, V, VI and VII of the Periodic Table. The compositions can be prepared using any solution based methods involving a surfactant approach or a sol gel approach. Further, the compositions are prepared using noble metal and non-noble metal precursors. Furthermore, a thin film containing the compositions can be deposited onto a substrate to form the anode electrode. |
FILED | Wednesday, December 21, 2016 |
APPL NO | 15/387100 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/10 (20130101) C25B 11/0405 (20130101) C25B 11/0484 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041701 | Koplow et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Jeffrey P. Koplow (San Ramon, California); Harumichi Arthur Kariya (Bellflower, California); Wayne Lawrence Staats, Jr. (Livermore, California) |
ABSTRACT | Embodiments disclosed herein relate to devices, systems, and methods for cooling and/or heating a medium as well as cooling and/or heating an environment containing the medium. More specifically, at least one embodiment includes a heat pump that may heat and/or cool a medium and, in some instances, may transfer heat from one location to another location. |
FILED | Tuesday, September 16, 2014 |
APPL NO | 14/487540 |
ART UNIT | 3744 — Static Structures, Supports and Furniture |
CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 1/005 (20130101) Original (OR) Class F25B 3/00 (20130101) F25B 41/043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041812 | Simpson et al. |
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FUNDED BY |
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APPLICANT(S) | Centrus Energy Corp. (Bethesda, Maryland) |
ASSIGNEE(S) | Centrus Energy Corp. (Bethesda, Maryland) |
INVENTOR(S) | Marc L. Simpson (Knoxville, Tennessee); Michael S. Emery (Powell, Tennessee); Caius V. Dodd (Aberdeen, Mississippi) |
ABSTRACT | A modified eddy current (MEC) probe includes a probe body having a bore formed therein. A printed circuit board (PCB) assembly includes a circuit board defining a plane, has a plurality of electronic components mounted thereon, and is configured for mounting within the bore of the probe body. A coil board assembly is electrically connected to the PCB assembly and comprises a coil board defining a plane, a transmitter coil formed on a first side of the coil board, and a sensor coil formed on second side of the coil board. The plane of the coil board is arranged orthogonally to the plane of the circuit board. |
FILED | Tuesday, January 24, 2017 |
APPL NO | 15/413504 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/2006 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/165 (20130101) H05K 1/0243 (20130101) H05K 2201/10151 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041859 | DeSilva et al. |
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FUNDED BY |
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APPLICANT(S) | Siemens Energy, Inc. (Orlando, Florida) |
ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
INVENTOR(S) | Upul P. DeSilva (Oviedo, Florida); Heiko Claussen (North Brunswick, New Jersey) |
ABSTRACT | A profile map of parameter values in a region is determined based on average values along linear paths through the region. In one example, a temperature map of a region of a gas turbine engine is created based on time-of-flight measurements from acoustic transceiver pairs arranged circumferentially around the region. A speed of sound for each transceiver pair is determined based on the time-of-flight measurements. An average temperature along each path is estimated from the time of flight, and the profile map is computed from the average temperatures. The profile map may be computed using a polynomial approximation technique, a grid optimization technique or a basis function technique. |
FILED | Thursday, April 09, 2015 |
APPL NO | 14/682393 |
ART UNIT | 3748 — Optics |
CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/668 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/24 (20130101) G01K 13/02 (20130101) G01K 2013/024 (20130101) G01K 2213/00 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041956 | Merchant et al. |
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FUNDED BY |
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APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Michael L. Merchant (Louisville, Kentucky); Jon B. Klein (Louisville, Kentucky); Michael E. Brier (Sellersburg, Indiana); Adam E. Gaweda (Jeffersonville, Indiana) |
ABSTRACT | Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent. |
FILED | Thursday, May 14, 2015 |
APPL NO | 14/712323 |
ART UNIT | 1678 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/6863 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042048 | Moya et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Mary M. Moya (Albuquerque, New Mexico); Mark W. Koch (Albuquerque, New Mexico); David Nikolaus Perkins (Albuquerque, New Mexico) |
ABSTRACT | Various embodiments presented herein relate to assigning labels to segments of a synthetic aperture radar (SAR) image, where the segments are based upon a speckle-reduced SAR image product. A plurality of SAR images of a scene are co-registered to form a registered stack of SAR images. A speckle-reduced SAR image product is generated based upon at least one registered SAR image in the registered stack of SAR images. The speckle-reduced SAR image product is segmented into a plurality of superpixels, and boundaries of the superpixels are applied to the at least one registered SAR image to form a segmented SAR image. A segment of the SAR image is then labeled as including or not including a feature, wherein the label is assigned based upon values of pixels in the segment. |
FILED | Thursday, February 19, 2015 |
APPL NO | 14/626582 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/9023 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042094 | Gee et al. |
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FUNDED BY |
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APPLICANT(S) | Randy Gee (Arvada, Colorado); Mike Digrazia (Longmont, Colorado); Gary Jorgensen (Pine, Colorado) |
ASSIGNEE(S) | SkyFuel, Inc. (Lakewood, Colorado); Alliance For Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Randy Gee (Arvada, Colorado); Mike Digrazia (Longmont, Colorado); Gary Jorgensen (Pine, Colorado) |
ABSTRACT | Described herein are solar reflectors which provide a low cost reflector construction that has a unique set of attributes: high solar reflectance, abrasion resistance, UV stability, mechanical integrity, and flexibility. The abrasion resistance is enabled through incorporation of an abrasion-resistant coating into a polymer film metal mirror construction. Methods of using the solar reflectors in solar concentrating applications are also provided. |
FILED | Tuesday, September 06, 2011 |
APPL NO | 14/342731 |
ART UNIT | 3749 — Optics |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) B32B 15/09 (20130101) B32B 15/20 (20130101) B32B 2255/10 (20130101) B32B 2307/71 (20130101) B32B 2307/416 (20130101) B32B 2307/584 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/46 (20130101) Optical Elements, Systems, or Apparatus G02B 1/14 (20150115) G02B 1/105 (20130101) G02B 5/0808 (20130101) Original (OR) Class G02B 19/0019 (20130101) G02B 19/0042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042123 | Rinzler et al. |
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FUNDED BY |
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APPLICANT(S) | Foro Energy, Inc. (Houston, Texas) |
ASSIGNEE(S) | Foro Energy (Littleton, Colorado) |
INVENTOR(S) | Charles C. Rinzler (Boston, Massachusetts); William C. Gray (Parker, Colorado); Jason D. Fraze (Littleton, Colorado); Brian O. Faircloth (Evergreen, Colorado); Mark S. Zediker (Castle Rock, Colorado); Ryan P. McKay (Littleton, Colorado) |
ABSTRACT | There are provided high power laser connectors and couplers and methods that are capable of providing high laser power without the need for active cooling to remote, harsh and difficult to access locations and under difficult and harsh conditions and to manage and mitigate the adverse effects of back reflections. |
FILED | Thursday, May 05, 2016 |
APPL NO | 15/147269 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/262 (20130101) G02B 6/3624 (20130101) Original (OR) Class G02B 6/3813 (20130101) G02B 6/3814 (20130101) G02B 6/3818 (20130101) G02B 6/4296 (20130101) G02B 6/4427 (20130101) G02B 2006/4297 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/042 (20130101) H01S 3/0064 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042397 | Rasmussen et al. |
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FUNDED BY |
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APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho) |
ASSIGNEE(S) | BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho) |
INVENTOR(S) | Nikki Rasmussen (Rexburg, Idaho); Reston A Condit (Idaho Falls, Idaho) |
ABSTRACT | A potted electronic device comprises an electronic device at least partially encapsulated by an energetic potting material. The energetic potting material comprises a halogenated urethane binder and a metal fuel dispersed within the halogenated urethane binder. Related energetic potting materials and methods of forming electronic devices at least partially encapsulated with the energetic potting materials are also disclosed. |
FILED | Thursday, February 18, 2016 |
APPL NO | 15/046979 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 27/00 (20130101) C06B 43/00 (20130101) C06B 45/18 (20130101) C06B 45/105 (20130101) Electric Digital Data Processing G06F 1/182 (20130101) Original (OR) Class G06F 21/86 (20130101) G06F 2221/2143 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/111 (20130101) H05K 1/115 (20130101) H05K 5/0208 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042517 | Stolte et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
INVENTOR(S) | Chris Stolte (Seattle, Washington); Diane L. Tang (Palo Alto, California); Patrick Hanrahan (Portola Valley, California) |
ABSTRACT | An exemplary method of generating a chart matrix comprises outputting a user interface (UI) comprising a row header UI section, a column header UI section, and a grid header UI section in a headers UI section, outputting a chart matrix defined by associating a first data dimension corresponding to a data dimension placed in a first position in the row header with a row edge of the chart matrix, and a second data dimension corresponding to a data dimension placed in a first position in the column header with a column edge of the chart matrix, outputting two or more charts nested within each of two or more cells of the chart matrix, providing a user option to perform a drill operation on a selected member displayed in the chart matrix, and outputting, in response to the user input to perform the drill operation, a modified chart matrix. |
FILED | Friday, April 28, 2017 |
APPL NO | 15/582478 |
ART UNIT | 2155 — Graphical User Interface and Document Processing |
CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) Original (OR) Class G06F 3/04847 (20130101) G06F 17/245 (20130101) G06F 17/30315 (20130101) G06F 17/30589 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042762 | Jayasena et al. |
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FUNDED BY |
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APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
INVENTOR(S) | Nuwan Jayasena (Sunnyvale, California); Michael Boyer (Bellevue, Washington) |
ABSTRACT | A data processing system includes a plurality of processors, local memories associated with a corresponding processor, and at least one inter-processor link. In response to a first processor performing a load or store operation on an address of a corresponding local memory that is not currently in the local cache, a local cache allocates a first cache line and encodes a local state with the first cache line. In response to a load operation from an address of a remote memory that is not currently in the local cache, the local cache allocates a second cache line and encodes a remote state with the second cache line. The first processor performs subsequent loads and stores on the first cache line in the local cache in response to the local state, and subsequent loads from the second cache line in the local cache in response to the remote state. |
FILED | Wednesday, September 14, 2016 |
APPL NO | 15/264804 |
ART UNIT | 2139 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 12/0811 (20130101) Original (OR) Class G06F 12/0815 (20130101) G06F 2212/62 (20130101) G06F 2212/283 (20130101) G06F 2212/621 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042901 | Stolte et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, California) |
INVENTOR(S) | Chris Stolte (Seattle, Washington); Diane L. Tang (Palo Alto, California); Patrick Hanrahan (Portola Valley, California) |
ABSTRACT | An exemplary method of generating a plurality of data visualizations comprises displaying a graphical user interface that includes a schema information region and a data visualization region. The method further includes receiving user actions to associate first, second, and third fields included in the schema information region with a plurality of shelves of the data visualization region. The method further includes generating a plurality of data visualizations in the data visualization region in accordance with the received user actions, each data visualization includes a plurality of data marks corresponding to a respective retrieved tuple of data having the first, second, and third fields. Moreover, each of the data marks has an x-position and y-position defined according to data for the first and second fields, respectively. In addition, each of the data visualizations corresponds to a respective unique value of the third field, and is displayed in a respective pane. |
FILED | Friday, March 03, 2017 |
APPL NO | 15/449844 |
ART UNIT | 2155 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 17/3056 (20130101) G06F 17/30294 (20130101) G06F 17/30554 (20130101) Original (OR) Class G06F 17/30572 (20130101) G06F 17/30592 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042960 | Ma |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Tian J. Ma (Albuquerque, New Mexico) |
ABSTRACT | Methods and apparatuses for identifying a track for a target are disclosed herein. In a general embodiment, trees for targets are identified. Each tree in the trees includes observations that are connected to each other by branches and each observation has a score. A selected track in a tree is identified within the trees with an observation having a highest score. A group of branches is added to the selected track from other trees other than the tree having the selected track to form the track for a target, enabling reducing processing resources used to identify the track. |
FILED | Thursday, March 19, 2015 |
APPL NO | 14/662666 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 17/30961 (20130101) Original (OR) Class G06F 17/30967 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043855 | Agarwal et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Sapan Agarwal (Dublin, California); Matthew Marinella (Gilbert, Arizona) |
ABSTRACT | Various technologies for improving uniformity of operation of elements in an array circuit are described herein. In an exemplary embodiment, a plurality of resistive elements are incorporated into an array circuit such that voltages developed across any two elements is substantially the same when an equal voltage is applied to energize the elements. In a crossbar array circuit that comprises a plurality of elements arranged in rows and columns, the resistance of each of the resistive elements is based upon a row or column to which the resistive element is connected. |
FILED | Thursday, December 14, 2017 |
APPL NO | 15/841670 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 5/14 (20130101) G11C 5/063 (20130101) G11C 5/147 (20130101) G11C 13/004 (20130101) G11C 13/0023 (20130101) G11C 13/0026 (20130101) G11C 13/0028 (20130101) G11C 13/0033 (20130101) G11C 13/0069 (20130101) G11C 2013/005 (20130101) G11C 2013/009 (20130101) G11C 2213/72 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/156 (20130101) H01L 27/2409 (20130101) H01L 27/2463 (20130101) Original (OR) Class H01L 27/3276 (20130101) H01L 28/20 (20130101) H01L 45/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043898 | Lal |
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FUNDED BY |
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APPLICANT(S) | Transphorm Inc. (Goleta, California) |
ASSIGNEE(S) | Transphorm Inc. (Goleta, California) |
INVENTOR(S) | Rakesh K. Lal (Isla Vista, California) |
ABSTRACT | A III-N enhancement-mode transistor includes a III-N structure including a conductive channel, source and drain contacts, and a gate electrode between the source and drain contacts. An insulator layer is over the III-N structure, with a recess formed through the insulator layer in a gate region of the transistor, with the gate electrode at least partially in the recess. The transistor further includes a field plate having a portion between the gate electrode and the drain contact, the field plate being electrically connected to the source contact. The gate electrode includes an extending portion that is outside the recess and extends towards the drain contact. The separation between the conductive channel and the extending portion of the gate electrode is greater than the separation between the conductive channel and the portion of the field plate that is between the gate electrode and the drain contact. |
FILED | Thursday, February 23, 2017 |
APPL NO | 15/440404 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0217 (20130101) H01L 21/0254 (20130101) H01L 21/8252 (20130101) H01L 23/291 (20130101) H01L 23/535 (20130101) H01L 23/3171 (20130101) H01L 24/48 (20130101) H01L 27/0605 (20130101) H01L 27/0629 (20130101) H01L 27/0883 (20130101) H01L 29/404 (20130101) H01L 29/518 (20130101) H01L 29/2003 (20130101) H01L 29/4175 (20130101) H01L 29/4236 (20130101) H01L 29/7787 (20130101) Original (OR) Class H01L 29/66462 (20130101) H01L 2224/4813 (20130101) H01L 2224/48091 (20130101) H01L 2924/1033 (20130101) H01L 2924/10323 (20130101) H01L 2924/10344 (20130101) H01L 2924/10346 (20130101) H01L 2924/13064 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043922 | Heben et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
ASSIGNEE(S) | The University Of Toledo (Toledo, Ohio) |
INVENTOR(S) | Michael J. Heben (Ottawa Hills, Ohio); Adam B. Phillips (Toledo, Ohio); Rajendra R. Khanal (Toledo, Ohio); Victor V. Plotnikov (Toledo, Ohio); Alvin D. Compaan (Holland, Ohio) |
ABSTRACT | A photovoltaic cell structure is disclosed that includes a back contact layer that includes single wall carbon nanotube elements. The single wall carbon nanotube (SWNT) back contact is in electrical communication with an adjacent semiconductor layer and provides a buffer characteristic that impedes elemental metal migration from the back contact into the semiconductor active layers. In one embodiment, the SWNT back contact includes a semiconductor characteristic and a buffer characteristic. In another embodiment, the SWNT back contact further includes a metallic characteristic. |
FILED | Tuesday, August 13, 2013 |
APPL NO | 14/421718 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/073 (20130101) H01L 31/075 (20130101) H01L 31/076 (20130101) H01L 31/077 (20130101) H01L 31/0725 (20130101) H01L 31/1828 (20130101) H01L 31/02008 (20130101) H01L 31/02167 (20130101) H01L 31/022425 (20130101) Original (OR) Class H01L 31/022441 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) Y02E 10/543 (20130101) Y02E 10/548 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043932 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Gang Chen (Carlisle, Massachusetts); Evelyn N. Wang (Cambridge, Massachusetts); Svetlana V. Boriskina (Winchester, Massachusetts); Kenneth McEnaney (Cornish, New Hampshire); Hadi Ghasemi (Boston, Massachusetts); Selcuk Yerci (Brighton, Massachusetts); Andrej Lenert (Cambridge, Massachusetts); Sungwoo Yang (Somerville, Massachusetts); Nenad Miljkovic (Cambridge, Massachusetts); Lee A. Weinstein (Somerville, Massachusetts); David Bierman (Cambridge, Massachusetts) |
ABSTRACT | A single-stack, solar power receiver comprising both a thermal absorber layer and a photovoltaic cell layer. The stack includes an aerogel layer, that is optically transparent and thermally insulating (“OTTI”); a spectrally selective high thermal conductivity (“SSTC”) thermal absorber layer; a bottom OTTI layer; and a PV cell layer. The SSTC layer includes a set of fins that substantially blocks solar radiation absorption in the band where PV cells are most sensitive. Photons with energies above or below this band block range are absorbed by the fins and the absorbed heat is conducted to pipes in the fin structure carrying a heated thermal working fluid to heat storage. Photons with energy in the band block range are reflected by the SSTC fins to the PV cell layer. The bottom OTTI aerogel layer keeps the PV cell operating near ambient temperature. The PV cell converts incident solar radiation to electrical energy. |
FILED | Wednesday, August 20, 2014 |
APPL NO | 14/464103 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Producing or Use of Heat Not Otherwise Provided For F24J 2/07 (20130101) F24J 2/085 (20130101) F24J 2/245 (20130101) F24J 2/485 (20130101) F24J 2/505 (20130101) F24J 2/541 (20130101) F24J 2002/508 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/052 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/44 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) Y02E 10/43 (20130101) Y02E 10/44 (20130101) Y02E 10/47 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044031 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Yuegang Zhang (Cupertino, California); Elton J. Cairns (Walnut Creek, California); Liwen Ji (Richland, Washington); Mumin Rao (El Cerrito, California) |
ABSTRACT | A battery is described. The battery is composed of a graphene oxide-sulfur (GO-S) nanocomposite cathode, a separator, an anode, and an electrolyte. |
FILED | Friday, November 17, 2017 |
APPL NO | 15/817051 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/23 (20170801) C01B 32/70 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2002/88 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2006/40 (20130101) Heterocyclic Compounds C07D 303/38 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) Original (OR) Class H01M 4/382 (20130101) H01M 4/587 (20130101) H01M 10/0525 (20130101) H01M 10/0566 (20130101) H01M 2300/0045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044038 | Bridges et al. |
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FUNDED BY |
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APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Craig A. Bridges (Oak Ridges, Tennessee); Mariappan Parans Paranthaman (Knoxville, Tennessee); Gabriel M. Veith (Knoxville, Tennessee); Zhonghe Bi (Oak Ridge, Tennessee) |
ABSTRACT | Compositions and methods of making compositions are provided for nitride- and/or oxide-modified electrode compositions. In certain embodiments, the nitride- and/or oxide-modified compositions have the general formula M1−zM′zOaF3−xNy. Such compositions may be used as bulk or surface compositions, and used in a battery as the anode or cathode. In other embodiments, the electrode includes a surface coating composition selected from metal nitrides and metal oxides, and a core composition having the formula M1−zM′zOaF3−x, or an oxide fluoride. |
FILED | Friday, August 29, 2014 |
APPL NO | 14/473099 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) Original (OR) Class H01M 4/136 (20130101) H01M 4/366 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044039 | Dai et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Batelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Sheng Dai (Knoxville, Tennessee); Xiao-Guang Sun (Knoxville, Tennessee); Bingkun Guo (Knoxville, Tennessee); Xiqing Wang (Mason, Ohio); Richard T. Mayes (Knoxville, Tennessee); Teng Ben (Changchun, China PRC); Shilun Qiu (Changchun, China PRC) |
ABSTRACT | The invention is directed in a first aspect to electron-conducting porous compositions comprising an organic polymer matrix doped with nitrogen atoms and having elemental sulfur dispersed therein, particularly such compositions having an ordered framework structure. The invention is also directed to composites of such S/N-doped electron-conducting porous aromatic framework (PAF) compositions, or composites of an S/N-doped mesoporous carbon composition, which includes the S/N-doped composition in admixture with a binder, and optionally, conductive carbon. The invention is further directed to cathodes for a lithium-sulfur battery in which such composites are incorporated. |
FILED | Friday, August 26, 2016 |
APPL NO | 15/248349 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/137 (20130101) H01M 4/602 (20130101) Original (OR) Class H01M 4/606 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044056 | Goettler et al. |
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FUNDED BY |
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APPLICANT(S) | LG Fuel Cell Systems, Inc. (North Canton, Ohio) |
ASSIGNEE(S) | LG FUEL CELL SYSTEMS, INC. (North Canton, Ohio) |
INVENTOR(S) | Richard W. Goettler (Medina, Ohio); Liang Xue (Canton, Ohio) |
ABSTRACT | In some examples, solid oxide fuel cell system comprising a solid oxide fuel cell including an anode, an anode conductor layer, a cathode, a cathode conductor layer, and electrolyte, wherein the anode and the anode conductor layer each comprise nickel; and a sacrificial nickel source separate from that of the anode and anode conductor layer, wherein the sacrificial nickel source is configured to reduce the loss or migration of the nickel of the anode and/or the anode current collector in the fuel cell during operation. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/213590 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/905 (20130101) H01M 4/8621 (20130101) H01M 8/243 (20130101) H01M 8/1213 (20130101) Original (OR) Class H01M 8/2404 (20160201) H01M 2008/1293 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044058 | Darling et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Robert Mason Darling (South Windsor, Connecticut); Rachid Zaffou (West Hartford, Connecticut); Michael L. Perry (Glastonbury, Connecticut); Craig R. Walker (South Glastonbury, Connecticut) |
ABSTRACT | A flow battery includes at least a cell that has a first electrode, a second electrode and an electrolyte separator layer arranged between the electrodes. A supply/storage system is external of the cell and includes a first vessel fluidly connected in a first loop with the first electrode and a second vessel fluidly connected in a second loop with the second electrode. The first loop and the second loop are isolated from each other. The supply/storage system is configured to fluidly connect the first loop and the second loop to move a second liquid electrolyte from the second vessel into a first liquid electrolyte in the first vessel responsive to a half-cell potential at the first electrode being less than a defined threshold half-cell potential. |
FILED | Friday, March 15, 2013 |
APPL NO | 14/770969 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/20 (20130101) H01M 8/188 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044061 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico); Board of Regents of the Nevada System of Higher Education,on behalf of the University of Nevada, Las Vegas, NV (Las Vegas, Nevada) |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Xujie Lu (Los Alamos, New Mexico); John Howard (Las Vegas, Nevada); Luc Daemen (Oak Ridge, Tennessee); Yusheng Zhao (Las Vegas, Nevada); Quanxi Jia (Los Alamos, New Mexico) |
ABSTRACT | A process for preparing a lithium-rich antiperovskite electrolyte film involves forming a composite target of precursor metal oxide(s) and metal halide(s), and exposing the target to a pulsed laser beam under conditions suitable for depositing a film of lithium-rich antiperovskite on a surface. In some embodiments the process is used to prepare a film of Li3OCl from a target largely composed of Li2O and LiCl. Exposure of the target to a pulsed laser beam deposits antiperovskite electrolyte Li3OCl on a substrate. In another embodiment, sputtering may be used to prepare films of lithium-rich antiperovskites using the composite target of precursor metal oxide(s) and metal halide(s). |
FILED | Wednesday, June 10, 2015 |
APPL NO | 14/736109 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/553 (20130101) C04B 35/5152 (20130101) C04B 2235/3203 (20130101) C04B 2235/3206 (20130101) C04B 2235/3208 (20130101) C04B 2235/3213 (20130101) C04B 2235/3215 (20130101) C04B 2235/3217 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/06 (20130101) C23C 14/28 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/06 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044504 | Nordholt et al. |
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FUNDED BY |
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APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Jane E. Nordholt (Los Alamos, New Mexico); Richard J. Hughes (Los Alamos, New Mexico); Raymond T. Newell (Santa Fe, New Mexico); Charles G. Peterson (Los Alamos, New Mexico); Rolando D. Somma (Santa Fe, New Mexico) |
ABSTRACT | Multiple bit values can be encoded on a single photon in a quantum key distribution (QKD) system using a plurality of sidebands of an optical carrier frequency. Computational and conjugate bases can be defined, and photons decoded based on a selected state from either basis. If n sidebands are available, as many as log2n bits can be encoded on a single photon. Errors in detected bit values due to selection of an incorrect basis state or other errors can be at least partially corrected by bit distillation to identity bit strings for which a transmitter and a receiver record the same values, without insecure transmission of these values. |
FILED | Wednesday, July 16, 2014 |
APPL NO | 14/333419 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Transmission H04B 10/70 (20130101) H04B 10/85 (20130101) H04B 10/508 (20130101) H04B 10/5165 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) H04L 9/0852 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10045463 | Chainer et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); David P. Graybill (Staatsburg, New York); Madhusudan K. Iyengar (Foster City, California); Vinod Kamath (Raleigh, North Carolina); Bejoy J. Kochuparambil (Apex, North Carolina); Roger R. Schmidt (Pougkeepsie, New York); Mark E. Steinke (Durham, North Carolina) |
ABSTRACT | Methods are provided for facilitating cooling of an electronic component. The method includes providing a liquid-cooled cold plate and a thermal spreader associated with the cold plate. The cold plate includes multiple coolant-carrying channel sections extending within the cold plate, and a thermal conduction surface with a larger surface area than a surface area of the component to be cooled. The thermal spreader includes one or more heat pipes including multiple heat pipe sections. One or more heat pipe sections are partially aligned to a first region of the cold plate, that is, where aligned to the surface to be cooled, and partially aligned to a second region of the cold plate, which is outside the first region. The one or more heat pipes facilitate distribution of heat from the electronic component to coolant-carrying channel sections of the cold plate located in the second region of the cold plate. |
FILED | Monday, December 08, 2014 |
APPL NO | 14/562867 |
ART UNIT | 3744 — Cryptography and Security |
CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/02 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20336 (20130101) Original (OR) Class H05K 7/20509 (20130101) H05K 7/20772 (20130101) H05K 7/20936 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 10039474 | Taylor et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Russell H. Taylor (Severna Park, Maryland); Marcin Arkadiusz Balicki (Baltimore, Maryland) |
ABSTRACT | An embodiment in accordance with the present invention provides a tracking system architecture for tracking surgical tools in a surgical field. The system architecture is integrated into a mask placed directly on the face of the patient. The system can combine multiple imaging and range finding technologies for tracking the eye and the surgical instrumentation. The system can be used to generate a three dimensional scene for use during the surgical procedure. Additionally, the system can incorporate a modular design to account for variable anatomy. The system described is for eye surgery applications. However, the system could also be used for other procedures such as cochlear implant or craniotomy. |
FILED | Tuesday, January 28, 2014 |
APPL NO | 14/165972 |
ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/061 (20130101) Original (OR) Class A61B 34/20 (20160201) A61B 2034/2055 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039723 | Roe et al. |
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FUNDED BY |
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APPLICANT(S) | DeviceFarm Inc. (Newark, California) |
ASSIGNEE(S) | DeviceFarm, Inc. (Newark, California) |
INVENTOR(S) | Jeffrey N Roe (Pleasanton, California); Timothy C Grammer (Pleasant Hill, California); Raul Ignacio Barrera-Barraza (Fremont, California); Eric Tridas (St. Petersburg, Florida) |
ABSTRACT | A system and method includes delivery of a redox gas solution to treat onychomycosis, wherein the redox gas solution comprises a reactive species dissolved in a perfluorocarbon liquid, and wherein the reactive species may include, alone or in combination, one or more of reactive oxygen, reactive nitrogen, reactive chlorine, or reactive bromine species, and the perfluorocarbon liquid may include perfluorodecalin. |
FILED | Tuesday, March 21, 2017 |
APPL NO | 15/464761 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/025 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/44 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039782 | Roe et al. |
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FUNDED BY |
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APPLICANT(S) | DeviceFarm Inc. (Newark, California) |
ASSIGNEE(S) | DeviceFarm, Inc. (Newark, California) |
INVENTOR(S) | Jeffrey N Roe (San Ramon, California); Timothy C Grammer (Pleasant Hill, California); Michael P O'Neil (Dublin, California) |
ABSTRACT | A system and method includes delivery of a redox gas solution to treat onychomycosis, wherein the redox gas solution comprises a reactive species dissolved in a perfluorocarbon liquid, and wherein the reactive species may include, alone or in combination, one or more of reactive oxygen, reactive nitrogen, reactive chlorine, or reactive bromine species, and the perfluorocarbon liquid may include perfluorodecalin. |
FILED | Wednesday, December 09, 2015 |
APPL NO | 14/963552 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/02 (20130101) A61K 31/02 (20130101) A61K 33/00 (20130101) A61K 33/00 (20130101) A61K 33/04 (20130101) Original (OR) Class A61K 33/04 (20130101) A61K 33/20 (20130101) A61K 33/20 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039807 | Maynard et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Heather D. Maynard (Los Angeles, California); Thi Nguyen (Reseda, California) |
ABSTRACT | A heparin mimicking polymer, its conjugate with bFGF, and method of making and using the same are disclosed. In particular, described herein are conjugates of biologic agents (e.g., bFGF) and heparin mimicking polymers having superior stability while retaining full native activity after a variety of stressors. |
FILED | Wednesday, February 08, 2017 |
APPL NO | 15/427918 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/78 (20130101) A61K 31/795 (20130101) A61K 38/1825 (20130101) Original (OR) Class A61K 47/32 (20130101) Peptides C07K 14/503 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 212/14 (20130101) C08F 220/28 (20130101) C08F 2220/286 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040834 | Omenetto et al. |
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FUNDED BY |
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APPLICANT(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
ASSIGNEE(S) | TUFTS UNIVERSITY (Medford, Massachusetts) |
INVENTOR(S) | Fiorenzo Omenetto (Lexington, Massachusetts); David L. Kaplan (Concord, Massachusetts); Brian Lawrence (New York, New York); Mark Cronin-Golomb (Reading, Massachusetts) |
ABSTRACT | A method of manufacturing a biopolymer optofluidic device including providing a biopolymer, processing the biopolymer to yield a biopolymer matrix solution, providing a substrate, casting the biopolymer matrix solution on the substrate, embedding a channel mold in the biopolymer matrix solution, drying the biopolymer matrix solution to solidify biopolymer optofluidic device, and extracting the embedded channel mold to provide a fluidic channel in the solidified biopolymer optofluidic device. In accordance with another aspect, an optofluidic device is provided that is made of a biopolymer and that has a channel therein for conveying fluid. |
FILED | Monday, January 13, 2014 |
APPL NO | 14/154134 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/02 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) B29D 11/00663 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2211/04 (20130101) D10B 2401/20 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) G01N 33/5436 (20130101) G01N 33/54373 (20130101) G01N 33/54386 (20130101) G01N 2333/43578 (20130101) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 1/005 (20130101) G02B 1/06 (20130101) G02B 1/041 (20130101) G02B 1/045 (20130101) G02B 1/046 (20130101) G02B 5/18 (20130101) G02B 6/138 (20130101) G02B 2006/1213 (20130101) G02B 2006/12102 (20130101) G02B 2006/12104 (20130101) G02B 2006/12107 (20130101) G02B 2006/12171 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040874 | Mattoussi et al. |
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FUNDED BY |
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APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
INVENTOR(S) | Hedi Mattoussi (Tallahassee, Florida); Wentao Wang (Tallahassee, Florida) |
ABSTRACT | The disclosure is directed to a set of multi-coordinating imidazole- and zwitterion-based ligands suited for surface-functionalizing quantum dots (QDs). The polymeric ligands are built using a one-step nucleophilic addition reaction between poly(isobutylene-alt-maleic anhydride) and distinct amine-containing functionalities. |
FILED | Friday, August 19, 2016 |
APPL NO | 15/241203 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/32 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 123/36 (20130101) C09D 133/064 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/883 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/774 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041045 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey); HACKENSACK UNIVERSITY MEDICAL CENTER (Hackensack, New Jersey) |
ASSIGNEE(S) | HACKENSACK UNIVERSITY MEDICAL CENTER (Hackensack, New Jersey); THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
INVENTOR(S) | Woo Young Lee (Lyndhurst, New Jersey); Yexin Gu (North Bergen, New Jersey); Qiaoling Sun (Secaucus, New Jersey); Wenting Zhang (Kearny, New Jersey); Jenny Zilberberg (Yardley, Pennsylvania) |
ABSTRACT | A bed of microbeads is used as a foundation for reconstructing a three-dimensional osteocyte network by culturing osteocytes within the bed. The osteocytes are cultured such that they form a network among the microbeads that is capable of simulating the osteocyte network of natural bone. The osteocytes are cultured in a microfluidic device adapted for the purpose. |
FILED | Friday, September 19, 2014 |
APPL NO | 14/490847 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 25/16 (20130101) C12M 29/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0654 (20130101) Original (OR) Class C12N 2531/00 (20130101) C12N 2533/54 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5026 (20130101) G01N 33/5044 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041168 | Boyd et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | David A. Boyd (La Cañada Flintridge, California); Nai-Chang Yeh (Pasadena, California) |
ABSTRACT | A method of forming graphene includes placing a substrate in a processing chamber and introducing a cleaning gas including hydrogen and nitrogen into the processing chamber. The method also includes introducing a carbon source into the processing chamber and initiating a microwave plasma in the processing chamber. The method further includes subjecting the substrate to a flow of the cleaning gas and the carbon source for a predetermined period of time to form the graphene. |
FILED | Friday, January 10, 2014 |
APPL NO | 14/152751 |
ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) C01B 32/186 (20170801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Original (OR) Class C23C 16/511 (20130101) C23C 16/4405 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24355 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042384 | Mallada et al. |
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FUNDED BY |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Enrique Mallada (Pasadena, California); Ao Tang (Ithaca, New York) |
ABSTRACT | A clock synchronization system and methods including an algorithm, or protocol, that synchronizes to any source of time without the need of estimating frequency errors and only performing frequency adaptions. Specifically, a clock synchronization protocol synchronizes networked nodes without explicit estimation of the clock skews and steep corrections on the time. The algorithm is guaranteed to converge even in the presence of timing loops which allow different clients to share timing information and even collectively outperform individual clients when the time source has large jitter. |
FILED | Tuesday, September 16, 2014 |
APPL NO | 15/021782 |
ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/10 (20130101) G06F 1/12 (20130101) Original (OR) Class Multiplex Communication H04J 3/0667 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0012 (20130101) H04L 7/0016 (20130101) H04L 69/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043099 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | James Z. Wang (State College, Pennsylvania); Xin Lu (State College, Pennsylvania); Poonam Suryanarayan (San Francisco, California); Reginald B. Adams (Pennsylvania Furnace, Pennsylvania); Jia Li (State College, Pennsylvania); Michelle Newman (State College, Pennsylvania) |
ABSTRACT | Shape features in natural images influence emotions aroused in human beings. An in-depth statistical analysis helps to understand the relationship between shapes and emotions. Through experimental results on the International Affective Picture System (IAPS) dataset, evidence is presented as to the significance of roundness-angularity and simplicity-complexity on predicting emotional content in images. Shape features are combined with other state-of-the-art features to show a gain in prediction and classification accuracy. Emotions are modeled from a dimensional perspective in order to predict valence and arousal ratings, which have advantages over modeling the traditional discrete emotional categories. Images are distinguished vis-a-vis strong emotional content from emotionally neutral images with high accuracy. All of the methods and steps disclosed herein are implemented on a programmed digital computer, which may be a stand-alone machine or integrated into another piece of equipment such as a digital still or video camera including, in all embodiments, portable devices such as smart phones. |
FILED | Thursday, January 11, 2018 |
APPL NO | 15/868310 |
ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4671 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/60 (20130101) G06T 2207/10004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043990 | Zang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Ling Zang (Salt Lake City, Utah); Benjamin R. Bunes (Salt Lake City, Utah) |
ABSTRACT | A chemical sensing field effect transistor device is disclosed. The device can include a control gate structure interfacing a control side of a semiconductor channel region, a source region, and a drain region. The control gate structure can comprise a control gate dielectric and a control gate electrode. The device can include a sensing gate structure interfacing the semiconductor channel region, the source region, and the drain region at a sensing side of the semiconductor channel region opposite the control gate structure. The sensing gate structure can comprise a sensing gate dielectric, and a sensing gate electrode. The device can include a functional layer interfacing the sensing gate electrode opposite the sensing gate dielectric. The functional layer can have an exposed interface surface. The functional layer can be capable of binding with a target analyte material sufficient to create a measurable change in conductivity across the semiconductor channel region. |
FILED | Thursday, July 23, 2015 |
APPL NO | 14/807527 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4141 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/001 (20130101) H01L 51/0006 (20130101) H01L 51/0022 (20130101) H01L 51/0053 (20130101) H01L 51/0545 (20130101) H01L 51/0554 (20130101) Original (OR) Class H01L 51/0558 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044748 | Dagon et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia); Georgia Institute of Technology (Atlanta, Georgia) |
INVENTOR(S) | David Dagon (Tampa, Florida); Nick Feamster (Atlanta, Georgia); Wenke Lee (Atlanta, Georgia); Robert Edmonds (Woodstock, Georgia); Richard Lipton (Atlanta, Georgia); Anirudh Ramachandran (Atlanta, Georgia) |
ABSTRACT | A system and method for detecting a first network of compromised computers in a second network of computers, comprising: collecting Domain Name System (DNS) data for the second network; examining the collected data relative to DNS data from known comprised and/or uncompromised computers in the second network; and determining the existence of the first network and/or the identity of compromised computers in the second network based on the examination. |
FILED | Tuesday, February 09, 2016 |
APPL NO | 15/019272 |
ART UNIT | 2438 — Cryptography and Security |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 29/12066 (20130101) H04L 29/12301 (20130101) H04L 61/1511 (20130101) H04L 61/2076 (20130101) H04L 63/1425 (20130101) H04L 63/1441 (20130101) Original (OR) Class H04L 63/1491 (20130101) H04L 2463/144 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 10042078 | Sarraiocco |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Brett Sarraiocco (Atlantic City, New Jersey) |
ABSTRACT | An image screening apparatus includes an image scanner that scans an object and generates an image of the object; at least one portable image viewing device; and a controller including circuitry configured to transmit the generated image to the at least one portable image viewing device, trigger display of the transmitted image on a screen of at least one of the portable image viewing devices, and match the displayed image with the scanned object. An area of interest of the scanned object can be displayed on one portable image viewing device by hovering the one portable image viewing device over the area of interest. |
FILED | Friday, February 27, 2015 |
APPL NO | 14/633635 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/887 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0016 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00536 (20130101) G06K 9/00577 (20130101) G06K 9/00771 (20130101) G06K 9/3233 (20130101) G06K 9/3241 (20130101) G06K 9/6215 (20130101) G06K 9/6267 (20130101) G06K 2209/09 (20130101) Pictorial Communication, e.g Television H04N 5/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043004 | Cornell et al. |
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FUNDED BY |
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APPLICANT(S) | Denim Group, Ltd. (San Antonio, Texas) |
ASSIGNEE(S) | Denim Group, Ltd. (San Antonio, Texas) |
INVENTOR(S) | Dan Cornell (San Antonio, Texas); Mac Collins (San Antonio, Texas) |
ABSTRACT | The invention provides a method of correlating and merging static application security testing (SAST) and dynamic application security testing (DAST) for web and mobile applications. The invention provides a method for categorizing and comparing various endpoint objects including the path (i.e., location within the application's attack surface), one or more parameters, an HTTPMethod, a filename on the file system, line number, and mobile entry point. |
FILED | Friday, August 25, 2017 |
APPL NO | 15/687186 |
ART UNIT | 2497 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) Original (OR) Class G06F 21/563 (20130101) G06F 21/566 (20130101) G06F 21/577 (20130101) G06F 2221/033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043009 | Upchurch |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Jason R. Upchurch (Monument, Colorado) |
ABSTRACT | Technologies for analyzing software similarity include a computing device having access to a collection of sample software. The computing device identifies a number of code segments, such as basic blocks, within the software. The computing device normalizes each code segment by extracting the first data element of each computer instruction within the code segment. The first data element may be the first byte. The computing device calculates a probabilistic feature hash signature for each normalized code segment. The computing device may filter out known-good code segments by comparing signatures with a probabilistic hash filter generated from a collection of known-good software. The computing device calculates a similarity value between each pair of unfiltered, normalized code segments. The computing device generates a graph including the normalized code segments and the similarity values. The computing device may cluster the graph using a force-based clustering algorithm. |
FILED | Wednesday, September 24, 2014 |
APPL NO | 14/494751 |
ART UNIT | 2437 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 17/30713 (20130101) G06F 21/12 (20130101) G06F 21/563 (20130101) Original (OR) Class G06F 21/577 (20130101) G06F 2221/033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043012 | Cornell et al. |
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FUNDED BY |
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APPLICANT(S) | Denim Group, Ltd. (San Antonio, Texas) |
ASSIGNEE(S) | Denim Group, Ltd (San Antonio, Texas) |
INVENTOR(S) | Dan Cornell (San Antonio, Texas); Mac Collins (San Antonio, Texas) |
ABSTRACT | A method of correlating a static application security testing (SAST) finding and a dynamic application security testing (DAST) finding for an application having a file system with code files containing at least one artifact, which application has an application framework that may be classified as having either a direct framework or an indirect framework. |
FILED | Monday, February 01, 2016 |
APPL NO | 15/011817 |
ART UNIT | 2497 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043990 | Zang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Ling Zang (Salt Lake City, Utah); Benjamin R. Bunes (Salt Lake City, Utah) |
ABSTRACT | A chemical sensing field effect transistor device is disclosed. The device can include a control gate structure interfacing a control side of a semiconductor channel region, a source region, and a drain region. The control gate structure can comprise a control gate dielectric and a control gate electrode. The device can include a sensing gate structure interfacing the semiconductor channel region, the source region, and the drain region at a sensing side of the semiconductor channel region opposite the control gate structure. The sensing gate structure can comprise a sensing gate dielectric, and a sensing gate electrode. The device can include a functional layer interfacing the sensing gate electrode opposite the sensing gate dielectric. The functional layer can have an exposed interface surface. The functional layer can be capable of binding with a target analyte material sufficient to create a measurable change in conductivity across the semiconductor channel region. |
FILED | Thursday, July 23, 2015 |
APPL NO | 14/807527 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4141 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/001 (20130101) H01L 51/0006 (20130101) H01L 51/0022 (20130101) H01L 51/0053 (20130101) H01L 51/0545 (20130101) H01L 51/0554 (20130101) Original (OR) Class H01L 51/0558 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 10039818 | Briggs et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Biotechnology and Research Development Corporation (Peoria, Illinois) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Biotechnology Research and Development Corporation (Peoria, Illinois) |
INVENTOR(S) | Robert E. Briggs (Boone, Iowa); Fred M. Tatum (Ames, Iowa) |
ABSTRACT | This disclosure provides attenuated P. multocida strains which can be used to prepare vaccine compositions useful for protection against P. multocida. |
FILED | Thursday, May 05, 2016 |
APPL NO | 15/147045 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/102 (20130101) Original (OR) Class A61K 2039/522 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10039819 | Briggs et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Biotechnology Research and Development Corporation (Peoria, Illinois) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Biotechnology Research and Development Corporation (Peoria, Illinois) |
INVENTOR(S) | Robert E. Briggs (Boone, Iowa); Fred M. Tatum (Nevada, Iowa) |
ABSTRACT | The present invention provides attenuated M haemolitica strains that elicit an immune response in animal against M haemolitica, compositions comprising said strains, methods of vaccination against M haemolitica, and kits for use with such methods and compositions. The invention further provides multi-valent vaccines, which provide protective immunity when administered in an effective amount to animals susceptible to “shipping fever” or bovine respiratory disease. |
FILED | Thursday, June 15, 2017 |
APPL NO | 15/624345 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/102 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/522 (20130101) A61K 2039/543 (20130101) A61K 2039/552 (20130101) Peptides C07K 14/285 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041136 | St. John et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Franz St. John (Madison, Wisconsin); Diane Dietrich (Madison, Wisconsin); Merritt E. Casey Crooks (Madison, Wisconsin) |
ABSTRACT | The invention provides a unique subset of GH30 subfamily 8 xylanases (GH30-8) with endo-β-1,4-xylanase activity, compositions comprising an effective amount of the GH30-8 xylanases, methods of synthesis and methods of use thereof. |
FILED | Thursday, July 09, 2015 |
APPL NO | 14/795296 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2482 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/14 (20130101) Enzymes C12Y 302/01008 (20130101) Original (OR) Class Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 13/002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP29575 | Brand |
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FUNDED BY |
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APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
ASSIGNEE(S) | University of Connecticut, Office of the Vice President for Research (Farmington, Connecticut) |
INVENTOR(S) | Mark Brand (Farmington, Connecticut) |
ABSTRACT | This invention relates to a compact, purple-leaf sand cherry plant that is easy to product, exhibits reliable landscape performance and colorful ornamental traits as shown herein and described. |
FILED | Tuesday, May 30, 2017 |
APPL NO | 15/731338 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/226 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 10039285 | Savage et al. |
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FUNDED BY |
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APPLICANT(S) | BRIGHAM YOUNG UNIVERSITY (Provo, Utah) |
ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
INVENTOR(S) | Paul B. Savage (Mapleton, Utah); Carl Genberg (Las Vegas, Nevada) |
ABSTRACT | Particulate ceragenin materials may be manufactured by (i) providing a ceragenin feed material comprised of ceragenin molecules, each having a sterol backbone and a plurality cationic groups attached thereto; (ii) fracturing the ceragenin feed material in a milling apparatus to produce a ceragenin particulate material having a particle size distribution with a median particle size in a range from 5 nm to 20 μm; and (iii) during fracturing, maintaining the ceragenin feed with a moisture content of less than or equal to 10% by weight. |
FILED | Wednesday, March 13, 2013 |
APPL NO | 14/398094 |
ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/12 (20130101) A01N 45/00 (20130101) Original (OR) Class A01N 45/00 (20130101) A01N 55/00 (20130101) A01N 55/08 (20130101) A01N 2300/00 (20130101) Crushing, Pulverising, or Disintegrating in General; Milling Grain B02C 23/12 (20130101) B02C 23/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040867 | Hansen et al. |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut); The United States of America as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut); The United States of America, as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | James E. Hansen (Guilford, Connecticut); Richard H. Weisbart (Los Angeles, California); Melissa Young (New Haven, Connecticut); Philip W. Noble (New Haven, Connecticut) |
ABSTRACT | It has been established that cancer cells with oncogenic mutants in the small GTPase K-Ras are susceptible to antibodies that bind intracellular guanosine, but delivery of antibodies into cells can be challenging. A subset of lupus autoantibodies is associated with anti-guanosine activity, and is capable of cellular penetration. These antibodies have potential as therapeutic agents targeted towards K-Ras associated malignancies. |
FILED | Wednesday, March 04, 2015 |
APPL NO | 15/123195 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 45/06 (20130101) Peptides C07K 16/30 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 16/44 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) C07K 2317/82 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) C07K 2317/622 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041956 | Merchant et al. |
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FUNDED BY |
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APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | Michael L. Merchant (Louisville, Kentucky); Jon B. Klein (Louisville, Kentucky); Michael E. Brier (Sellersburg, Indiana); Adam E. Gaweda (Jeffersonville, Indiana) |
ABSTRACT | Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent. |
FILED | Thursday, May 14, 2015 |
APPL NO | 14/712323 |
ART UNIT | 1678 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/6863 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043129 | Georgopoulos |
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FUNDED BY |
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APPLICANT(S) | Apostolos Georgopoulos (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Apostolos Georgopoulos (Minneapolis, Minnesota) |
ABSTRACT | A computer-implemented method for performing a functional assessment of a network is disclosed. The network includes a plurality of interacting network elements. The method includes measuring a state of each of the elements at a plurality of time instances, thereby determining a plurality of state values associated with each of the elements, and calculating for each element an associated median value representing a median of the state values associated with that element. The method further includes identifying for each time instance a first total number of elements with an associated state value at that time instance that is above its median value, and a second total number of elements with an associated state value at that time instance that is below its median value, and determining whether the network has departed from an equilibrium state based on the first total number and the second total number for each time instance. |
FILED | Tuesday, December 06, 2011 |
APPL NO | 13/312332 |
ART UNIT | 3768 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/04008 (20130101) A61B 5/4064 (20130101) A61B 5/6803 (20130101) A61B 5/7264 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 10039562 | Bailey et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
INVENTOR(S) | Michael Bailey (Seattle, Washington); Bryan Cunitz (Seattle, Washington); Barbrina Dunmire (Burien, Washington) |
ABSTRACT | Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects. |
FILED | Tuesday, March 07, 2017 |
APPL NO | 15/452590 |
ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/7232 (20130101) A61B 6/03 (20130101) A61B 6/485 (20130101) A61B 8/085 (20130101) A61B 8/488 (20130101) A61B 17/225 (20130101) Original (OR) Class A61B 17/2256 (20130101) A61B 2017/22005 (20130101) A61B 2090/378 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 2007/0004 (20130101) A61N 2007/0052 (20130101) A61N 2007/0082 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52071 (20130101) G01S 15/899 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041833 | Chirayath |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Adminstrator of the NASA (Washington, District of Columbia) |
INVENTOR(S) | Ved Chirayath (Palo Alto, California) |
ABSTRACT | Provided is a system and method for active multispectral imaging having a transmitter that uses narrowband optical radiation to dynamically illuminate an object with modulated structured light in multiple spectral bands, and a receiver that includes an independent panchromatic imager. The transmitter and receiver can be operated in a bistatic decoupled configuration to enable passive multispectral synthesis, illumination-invariant sensing, optical communications, and the ability for the transmitter to emit a sequence of spectral bands in an order that is unknown to the receiver, and the receiver is able to passively decode the spectral identity from a band identifier embedded in the modulated structured light. The receiver passively decodes embedded high-bandwidth simplex communications while reconstructing calibrated multispectral images at video frame rates. |
FILED | Wednesday, April 05, 2017 |
APPL NO | 15/480318 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/2823 (20130101) Original (OR) Class G01J 2003/425 (20130101) G01J 2003/2826 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10043990 | Zang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Ling Zang (Salt Lake City, Utah); Benjamin R. Bunes (Salt Lake City, Utah) |
ABSTRACT | A chemical sensing field effect transistor device is disclosed. The device can include a control gate structure interfacing a control side of a semiconductor channel region, a source region, and a drain region. The control gate structure can comprise a control gate dielectric and a control gate electrode. The device can include a sensing gate structure interfacing the semiconductor channel region, the source region, and the drain region at a sensing side of the semiconductor channel region opposite the control gate structure. The sensing gate structure can comprise a sensing gate dielectric, and a sensing gate electrode. The device can include a functional layer interfacing the sensing gate electrode opposite the sensing gate dielectric. The functional layer can have an exposed interface surface. The functional layer can be capable of binding with a target analyte material sufficient to create a measurable change in conductivity across the semiconductor channel region. |
FILED | Thursday, July 23, 2015 |
APPL NO | 14/807527 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4141 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/001 (20130101) H01L 51/0006 (20130101) H01L 51/0022 (20130101) H01L 51/0053 (20130101) H01L 51/0545 (20130101) H01L 51/0554 (20130101) Original (OR) Class H01L 51/0558 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044320 | Ehsan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Negar Ehsan (Bethesda, Maryland); Jeffrey R. Piepmeier (Millersville, Maryland); Edward J. Wollack (Clarksville, Maryland) |
ABSTRACT | Aspects of the present disclosure involve a system and method for generating noise waves at millimeter wave frequencies. A noise source generator is designed to be connected to a crystalline structure for efficient heat transfer and compatibility with millimeter wave receivers. The use of crystalline structure coupled to the noise source generator allows heat from a biasing device, such as a diode, to be carried away such that the diode is able to generate noise waves while being reversed biased without compromising the device. In another embodiment, the noise source generator includes the use of a backshort transmission line with vias that is connected to the biasing device for heat transfer from the biasing device to the backshort. |
FILED | Wednesday, August 31, 2016 |
APPL NO | 15/252559 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/2039 (20130101) H01P 5/107 (20130101) H01P 9/00 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 29/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 10042644 | Satpathy et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Sudhir K. Satpathy (Hillsboro, Oregon); Sanu K. Mathew (Hillsboro, Oregon); Vinodh Gopal (Westborough, Massachusetts); James D. Guilford (Northborough, Massachusetts) |
ABSTRACT | An apparatus and method for performing parallel decoding of prefix codes such as Huffman codes. For example, one embodiment of an apparatus comprises: a first decompression module to perform a non-speculative decompression of a first portion of a prefix code payload comprising a first plurality of symbols; and a second decompression module to perform speculative decompression of a second portion of the prefix code payload comprising a second plurality of symbols concurrently with the non-speculative decompression performed by the first compression module. |
FILED | Tuesday, December 06, 2016 |
APPL NO | 15/371091 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Electric Digital Data Processing G06F 9/3016 (20130101) G06F 9/30021 (20130101) G06F 9/30156 (20130101) G06F 9/30185 (20130101) Original (OR) Class Coding; Decoding; Code Conversion in General H03M 7/4037 (20130101) H03M 7/6005 (20130101) H03M 7/6023 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042928 | Brown et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States as represented by the Director, National Security Agency (Washington, District of Columbia) |
INVENTOR(S) | Raymond E. Brown (Arnold, Maryland); Daniel J. Clouse (Annapolis, Maryland); Duane J. Einfeld (Odenton, Maryland); John B. Maddox (Annapolis, Maryland); David J. Marcos (Washington, District of Columbia) |
ABSTRACT | A method and computer system architecture for providing to a computer user or to a downstream system a means of converting the content of documents including legal, policy, and compliance statements, using symbolic logic, into a logic ontology, which enables users to reason through the content of laws, policies, and procedures by means of automated reasoning. The system additionally includes a process for easily searching or navigating multiple facets of legal, policy, and compliance documents. |
FILED | Wednesday, December 03, 2014 |
APPL NO | 14/121006 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Electric Digital Data Processing G06F 17/30864 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10044626 | Underwood et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Keith Underwood (Powell, Tennessee); Charles Giefer (Seattle, Washington); Mark Debbage (Santa Clara, California); Karl P. Brummel (Chicago, Illinois); Nathan Miller (Seattle, Washington); Bruce Pirie (Renton, Washington) |
ABSTRACT | In an embodiment, an out-of-order, reliable, end-to-end protocol is provided that can enable direct user-level data placement and atomic operations between nodes of a multi-node network. The protocol may be optimized for low-loss environments such as High Performance Computing (HPC) applications, and may enable loss detection and de-duplication of packets through the use of a robust window state manager at a target node. A multi-node network implementing the protocol may have increased system reliability, packet throughput, and increased tolerance for adaptively routed traffic, while still allowing atomic operations to be idempotently applied directly to a user memory location. |
FILED | Thursday, December 24, 2015 |
APPL NO | 14/757993 |
ART UNIT | 2476 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/187 (20130101) H04L 1/1621 (20130101) H04L 1/1635 (20130101) H04L 1/1832 (20130101) H04L 47/18 (20130101) H04L 47/27 (20130101) H04L 47/34 (20130101) Original (OR) Class H04L 47/58 (20130101) H04L 69/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 10040835 | Luo |
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FUNDED BY |
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APPLICANT(S) | Wellstat Ophthalmics Corporation (Gaithersburg, Maryland) |
ASSIGNEE(S) | Wellstat Ophthalmics Corporation (Rockville, Maryland) |
INVENTOR(S) | Tianci Luo (Clarksville, Maryland) |
ABSTRACT | The present invention relates to nucleic acids coding for and capable of expressing a rod-derived cone viability factor (RdCVF) and viral vectors containing these nucleic acids. The invention also relates to compositions and pharmaceutical preparations comprising these nucleic acids or vectors, methods of producing or secreting an RdCVF, and methods of treatment. |
FILED | Tuesday, December 08, 2015 |
APPL NO | 14/962337 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/44 (20130101) A61K 48/0066 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0051 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2799/025 (20130101) C12N 2800/22 (20130101) C12N 2830/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10040840 | Antipov et al. |
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FUNDED BY |
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APPLICANT(S) | Silver Creek Pharmaceuticals, Inc. (San Francisco, California) |
ASSIGNEE(S) | Silver Creek Pharmaceuticals, Inc. (San Francisco, California) |
INVENTOR(S) | Laura D. J. Antipov (Oakland, California); Shawdee Eshghi (Oakland, California); Kristopher M. Kuchenbecker (Los Angeles, California); Bjorn L. Millard (Orinda, California); Matthew D. Onsum (El Cerrito, California); Andrea D. Nickerson (San Francisco, California); Timothy R. Stowe (San Francisco, California); Yan Zhang (San Francisco, California) |
ABSTRACT | Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. |
FILED | Friday, September 30, 2016 |
APPL NO | 15/281795 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/65 (20130101) Original (OR) Class C07K 14/765 (20130101) C07K 2319/33 (20130101) C07K 2319/035 (20130101) C07K 2319/75 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10041107 | Kazakov et al. |
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FUNDED BY |
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APPLICANT(S) | SomaGenics, Inc. (Santa Cruz, California) |
ASSIGNEE(S) | SOMAGENICS, INC. (Santa Cruz, California) |
INVENTOR(S) | Sergei A. Kazakov (San Jose, California); Pavan Kumar (Arlington, Massachusetts); Brian H. Johnston (Scotts Valley, California) |
ABSTRACT | Currently, the circularization of small RNAs is broadly regarded as an obstacle in ligation-related assays and explicitly avoided while short lengths of linear RNA targets is broadly recognized as a factor limiting use of conventional primers in PCR-related assays. In contrast, the disclosed invention capitalizes on circularization of small RNA targets or their conjugates with oligonucleotide adapters. The circular RNA templates provide amplification of the target sequences via synthesis of multimer nucleic acids that can be either labeled for direct detection or subjected to PCR amplification and detection. Structure of small circular RNAs and corresponding multimeric nucleic acids provide certain advantages over current methods including flexibility in design of conventional RT and PCR primers as well as use of 5′-overlapping dimer-primers for efficient and sequence-specific amplification of short target sequences. Our invention also reduces number of steps and reagents while increasing sensitivity and accuracy of detection of small RNAs with both 2′OH and 2′-OMe at their 3′ ends. Our invention increase sensitivity and specificity of detection of microRNAs and other small RNAs with both 2′OH and 2′-OMe at their 3′ ends while allowing us to distinguish these two forms from each other. |
FILED | Thursday, October 06, 2016 |
APPL NO | 15/287254 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6865 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 10041971 | Grinolds et al. |
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FUNDED BY |
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APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
INVENTOR(S) | Michael S. Grinolds (Somerville, Massachusetts); Sungkun Hong (Vienna, Austria); Patrick Maletinsky (Basel, Switzerland); Amir Yacoby (Newton, Massachusetts) |
ABSTRACT | A sensing probe may be formed of a diamond material comprising one or more spin defects that are configured to emit fluorescent light and are located no more than 50 nm from a sensing surface of the sensing probe. The sensing probe may include an optical outcoupling structure formed by the diamond material and configured to optically guide the fluorescent light toward an output end of the optical outcoupling structure. An optical detector may detect the fluorescent light that is emitted from the spin defects and that exits through the output end of the optical outcoupling structure after being optically guided therethrough. A mounting system may hold the sensing probe and control a distance between the sensing surface of the sensing probe and a surface of a sample while permitting relative motion between the sensing surface and the sample surface. |
FILED | Tuesday, August 20, 2013 |
APPL NO | 14/423123 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/645 (20130101) G01N 24/10 (20130101) G01N 2201/10 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/025 (20130101) G01Q 60/08 (20130101) G01Q 60/38 (20130101) G01Q 60/54 (20130101) G01Q 70/14 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) G01R 33/032 (20130101) G01R 33/60 (20130101) G01R 33/323 (20130101) G01R 33/1284 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
US 10041866 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
ASSIGNEE(S) | University of South Carolina (, None) |
INVENTOR(S) | Zhenyu Lu (Columbia, South Carolina); Brianna Cassidy (Columbia, South Carolina); Katherine Witherspoon (Columbia, South Carolina); Stephanie Dejong (Ripon, California); Raymond G. Belliveau, III (Columbia, South Carolina); Michael Myrick (Columbia, South Carolina); Stephen L. Morgan (Columbia, South Carolina) |
ABSTRACT | A stain-barrier is described along with methods of its application to a fabric. The stain barrier reduces variability between samples of different dilution or fabric type so that limits of stain detection can be assigned more accurately and precisely and stain detection techniques can be transparently compared. |
FILED | Friday, April 22, 2016 |
APPL NO | 15/136252 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Original (OR) Class G01N 33/49 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 10039445 | Torch |
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FUNDED BY |
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APPLICANT(S) | William C. Torch (Reno, Nevada) |
ASSIGNEE(S) | Google LLC (Mountain View, California) |
INVENTOR(S) | William C. Torch (Reno, Nevada) |
ABSTRACT | Biosensor, communicator, and/or controller apparatus, systems, and methods are provided for monitoring movement of a person's eye. The apparatus includes a device configured to be worn on a user's head, a light source for directing light towards one or both eyes of the user, one or more image guides on the device for viewing one or both eyes of the user, and one or more cameras carried on the device and coupled to the image guides for acquiring images of the eyes and/or the user's surroundings. The apparatus may include a cable and/or a transmitter for transmitting image data from the camera to a remote location, e.g., to processor and/or display for analyzing and/or displaying the image data. A system including the apparatus may be used to monitor one or more oculometric parameters, e.g., pupillary response, and/or to control a computer using the user's eyes instead of a mouse. |
FILED | Wednesday, January 13, 2010 |
APPL NO | 12/687125 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00009 (20130101) A61B 3/0025 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 10041622 | Bullard et al. |
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FUNDED BY |
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APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Andrew L. Bullard (Manhattan Beach, California); Shane E. Wilson (Torrance, California) |
ABSTRACT | A bi-directional spring member is mounted to a support platform, the bi-directional spring member being coupled to a payload. The bi-directional spring member includes a non-linear spring component having a rigid member enclosing at least a portion of a compliant planar member and a linear spring component. The compliant planar member flexes in a direction opposite a direction of low amplitude vibrational forces acting on the compliant planar member to reduce vibrational forces acting on the support platform and the linear spring member flexes to reduce high amplitude vibrational forces acting on the support platform. |
FILED | Friday, November 04, 2016 |
APPL NO | 15/344428 |
ART UNIT | 3631 — Static Structures, Supports and Furniture |
CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 3/02 (20130101) F16F 2228/066 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 11/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10042805 | Naaman et al. |
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FUNDED BY |
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APPLICANT(S) | Ofer Naaman (Ellicott City, Maryland); Zachary Kyle Keane (Baltimore, Maryland); Micah Stoutimore (Kensington, Maryland); David George Ferguson (Takoma Park, Maryland) |
ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
INVENTOR(S) | Ofer Naaman (Ellicott City, Maryland); Zachary Kyle Keane (Baltimore, Maryland); Micah Stoutimore (Kensington, Maryland); David George Ferguson (Takoma Park, Maryland) |
ABSTRACT | A tunable bus-mediated coupling system is provided that includes a first input port coupled to a first end of a variable inductance coupling element through a first resonator and a second input port coupled to a second end of the variable inductance coupling element through a second resonator. The first input port is configured to be coupled to a first qubit, and the second output port is configured to be coupled to a second qubit. A controller is configured to control the inductance of the variable inductance coupling element between a low inductance state to provide strong coupling between the first qubit and the second qubit and a high inductance state to provide isolation between the first qubit and the second qubit. |
FILED | Thursday, January 21, 2016 |
APPL NO | 15/003232 |
ART UNIT | 2184 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 13/4027 (20130101) Original (OR) Class G06F 13/4068 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) H01L 39/223 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 07, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180807.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page