FedInvent™ Patents
Patent Details for Tuesday, September 11, 2018
This page was updated on Monday, March 27, 2023 at 05:37 AM GMT
Department of Health and Human Services (HHS)
| US 10070643 | Deckelbaum et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Richard J. Deckelbaum (Hastings on Hudson, New York); Ravichandran Ramasamy (Ardsley, New York) |
| ABSTRACT | It has been discovered that isolated organs and tissues perfused/reperfused in perfusion buffer to which omega-3 glyceride oil had been added retain higher levels of function than if perfused/reperfused without the omega-3 glycerides. Isolated hearts reperfused ex vivo after induced ischemia in n-3 triglyceride perfusion emulsion maintained a normal heart rate and normal LVDP and showed a dramatically reduced frequency of arrhythmias compared to control hearts. Further, test hearts reperfused with n-3 oil triglyceride emulsion showed a decrease in creatine kinase and upregulation of certain beneficial proteins including the anti-apoptotic gene marker Bcl-2. |
| FILED | Friday, March 28, 2014 |
| APPL NO | 14/780832 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10070790 | Fitzgerald et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Colleen M. Fitzgerald (LaGrange, Illinois); Yasin Y. Dhaher (Mount Prospect, Illinois) |
| ABSTRACT | Systems and methods for the diagnosis of chronic pain are disclosed. An algometer comprising a pressure sensor and electrode is disclosed. The algometer may be used to measure pressure applied by a clinician at a location on a patient's body, along with EMG signals emanating from the same location of the patient. Further, a pain trigger operable by the patient may be used in coordination with the algometer. Data from the algometer and pain trigger are transmitted to a computing device and display for rendering and analysis of patient data, leading to improved diagnosis. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/213880 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0053 (20130101) Original (OR) Class A61B 5/483 (20130101) A61B 5/0492 (20130101) A61B 5/4827 (20130101) A61B 5/6843 (20130101) A61B 5/6885 (20130101) A61B 2560/0425 (20130101) A61B 2560/0462 (20130101) A61B 2560/0468 (20130101) A61B 2562/0209 (20130101) A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10070813 | Wang et al. |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | Lihong Wang (St. Louis, Missouri); Geng Ku (St. Louis, Missouri) |
| ABSTRACT | A system for imaging a biological sample including a tubular body having a side wall defining an interior shaped and sized for receiving the biological sample, an electromagnetic source positioned at one end of the tubular body interior for directing electromagnetic energy into the biological sample in the body interior, and an ultrasonic transducer positioned along said side wall of the body for receiving ultrasonic energy induced by the electromagnetic energy and transmitted through the biological sample. |
| FILED | Friday, August 12, 2016 |
| APPL NO | 15/235849 |
| ART UNIT | 3777 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0091 (20130101) A61B 5/0093 (20130101) A61B 5/0095 (20130101) A61B 5/4312 (20130101) Original (OR) Class A61B 8/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10070905 | Bottlang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Zimmer, Inc. (Warsaw, Indiana) |
| ASSIGNEE(S) | Zimmer, Inc. (Warsaw, Indiana) |
| INVENTOR(S) | Michael Bottlang (Happy Valley, Oregon); Steven M. Madey (West Linn, Oregon); Kyle Wirtz (Portland, Oregon); Stanley Tsai (Portland, Oregon) |
| ABSTRACT | A device can be provided that includes a bone plate having an upper surface and a bone-facing surface, wherein the bone plate includes one or more openings extending through the bone plate from the upper surface to the bone-facing surface, and one or more sliding elements each including a fastener receiving hole. The one or more openings can at least partially surround a periphery of one of the receiving holes. Further, the one or more openings can be at least partially filled with an elastomer to support elastic suspension of the one or more sliding elements in the bone plate, thereby enabling relative displacement between the one or more sliding elements and the bone plate. At least one sensor can also be provided that is operable to assess a dynamic parameter of one of the one or more sliding elements within the bone plate. |
| FILED | Friday, July 24, 2015 |
| APPL NO | 14/808773 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/86 (20130101) A61B 17/8047 (20130101) Original (OR) Class A61B 17/8057 (20130101) A61B 2017/00221 (20130101) A61B 2017/00862 (20130101) A61B 2560/0219 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10070989 | Keller |
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| FUNDED BY |
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| APPLICANT(S) | Mynosys Cellular Devices, Inc. (Fremont, California) |
| ASSIGNEE(S) | Mynosys Cellular Devices, Inc. (Fremont, California) |
| INVENTOR(S) | Christopher Guild Keller (El Cerrito, California) |
| ABSTRACT | A cartridge of a surgical device is disclosed that includes a capsulotomy device and a shell structure. The capsulotomy device includes a suction cup, a chamber configured to provide suction to the suction cup, and a cutting element that can be put into contact with a lens capsule of an eye to excise a portion of tissue of the lens capsule. Both the suction cup and cutting element are collapsible. The shell structure is configured for housing the capsulotomy device. The housing of the shell structure can contain the suction cup, the chamber, and the cutting element of the capsulotomy device to protect the device before it is used in performing a capsulotomy. |
| FILED | Tuesday, February 03, 2015 |
| APPL NO | 14/613112 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/082 (20130101) A61B 2018/00321 (20130101) A61B 2018/00601 (20130101) A61B 2018/00625 (20130101) A61B 2018/1407 (20130101) A61B 2018/1465 (20130101) A61B 2218/007 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00754 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071016 | Ludlow et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Christy Leslie Ludlow (Castleton, Virginia); Christopher Poletto (North Oaks, Minnesota); Ianessa A. Humbert (Silver Spring, Maryland) |
| ABSTRACT | Methods, devices and systems for recovering motor control of an area in the body of a patient affected by a neurological disorder. A device vibrotactilely stimulates a substitute site for the affected area thereby recovering the motor control of the affected area. The stimulation provided by the device is volitionally controlled by the patient. |
| FILED | Thursday, August 28, 2014 |
| APPL NO | 14/471369 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/02 (20130101) Original (OR) Class A61H 39/00 (20130101) A61H 39/002 (20130101) A61H 39/06 (20130101) A61H 39/007 (20130101) A61H 2039/005 (20130101) A61H 2201/12 (20130101) A61H 2201/16 (20130101) A61H 2201/50 (20130101) A61H 2205/04 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36003 (20130101) A61N 1/36007 (20130101) A61N 1/36017 (20130101) A61N 1/36025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071027 | Pfeifer et al. |
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| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Carmem S. Pfeifer (Portland, Oregon); Jack L. Ferracane (Portland, Oregon) |
| ABSTRACT | Disclosed herein are methacrylate compounds that can be used as components of dental composites. Also disclosed are dental composites comprising the compositions and thiourethane oligomers. |
| FILED | Tuesday, March 17, 2015 |
| APPL NO | 15/126751 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/0023 (20130101) A61K 6/083 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 271/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071076 | Kridel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Steven J. Kridel (Clemmons, North Carolina); W. Todd Lowther (Pfafftown, North Carolina); Herman H. Odens (Ooltewah, Tennessee); Jeffrey D. Schmitt (Asheville, North Carolina) |
| ABSTRACT | Active compounds useful for inhibiting fatty acid synthase in a subject in need thereof are described. The active compounds are, in general, a 5-mercapto-1H-Indazole-4,7-dione or an analog thereof. The compounds are useful for treating subjects afflicted with, cancer, obesity, diabetes, a viral infection, a bacterial infection, a fungal infection, or a protozoal infection. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 15/193793 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/416 (20130101) Original (OR) Class Heterocyclic Compounds C07D 231/56 (20130101) C07D 261/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071087 | Zheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas) |
| ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas) |
| INVENTOR(S) | Guangrong Zheng (Little Rock, Arkansas); Daohong Zhou (Little Rock, Arkansas); Xingui Liu (Little Rock, Arkansas); Yingying Wang (Little Rock, Arkansas); Jianhui Chang (Little Rock, Arkansas); Wei Feng (Little Rock, Arkansas); Lijian Shao (Little Rock, Arkansas); Yi Luo (Little Rock, Arkansas) |
| ABSTRACT | The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the composition comprises piperlongumine (PL) or derivative thereof. The selective killing of senescent cells may delay aging and/or treat age-related disorders. |
| FILED | Wednesday, July 22, 2015 |
| APPL NO | 15/328368 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/45 (20130101) Original (OR) Class A61K 31/55 (20130101) A61K 31/4015 (20130101) A61K 31/5377 (20130101) Heterocyclic Compounds C07D 207/38 (20130101) C07D 211/76 (20130101) C07D 211/88 (20130101) C07D 211/96 (20130101) C07D 223/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071101 | Mold |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeffrey Eron Mold (San Francisco, California) |
| ABSTRACT | The present invention provides compounds and methods for preventing and treating an immune disorder in a subject. |
| FILED | Monday, October 31, 2016 |
| APPL NO | 15/339609 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/538 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071110 | Hostetler et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Karl Y. Hostetler (Del Mar, California); James R. Beadle (San Diego, California) |
| ABSTRACT | The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and the like. |
| FILED | Monday, May 15, 2017 |
| APPL NO | 15/595496 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/20 (20130101) A61K 9/48 (20130101) A61K 9/0053 (20130101) A61K 31/675 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071121 | Sussman et al. |
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| APPLICANT(S) | San Diego State University (SDSU) Foundation (San Diego, California) |
| ASSIGNEE(S) | SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION (San Diego, California) |
| INVENTOR(S) | Mark A. Sussman (San Diego, California); Pearl J. Quijada (San Diego, California) |
| ABSTRACT | In alternative embodiments, provided are chimeric cells, which in alternative embodiments are the so-called “cardiochimeras”, and methods for making and using them. In alternative embodiments, exemplary chimeric cells as provided herein comprise a cardiac stem cell of cardiac origin or a cardiac progenitor cell fused to either a mesenchymal progenitor cell or mesenchymal stem cell, an endothelial progenitor cell or endothelial stem cell, or a cardiac stem cell or a cardiac progenitor cell. In alternative embodiments, the chimeric cells as provided herein comprise an endothelial progenitor cell, which may or may not be of cardiac origin, fused to either a mesenchymal progenitor cell or mesenchymal stem cell, an endothelial progenitor cell or endothelial stem cell, or a cardiac stem cell or a cardiac progenitor cell. In alternative embodiments, methods for making chimeric cells as provided herein further comprise selecting a cell fusion product comprising a viable chimera of the fused cells. In alternative embodiments, methods for making chimeric cells as provided herein comprise use of any known cell fusion technique, for example, using a Sendai virus, such as a Sendai virus Hemagglutinating Virus of Japan Envelope (HVJ-E), a polyethylene glycol, liposomes or lipids, a fusion protein, electrofusion and/or equivalents thereof. In alternative embodiments, provided are cell lines, chimera (chimeric) cell lines or chromosomally-stable chimera cell lines, derived or made from chimeric cells as provided herein. In alternative embodiments, provided are methods for inducing cardiogenesis in a mammalian heart comprising administration to an individual in need thereof (for example, a human), chimeric cells as provided herein, or a cell line, a chimera cell line or a chromosomally-stable chimera as provided herein. In alternative embodiments, provided are methods for treating or ameliorating a heart injury, a congenital or genetic heart defect, or a heart dysfunction, comprising administration to an individual in need thereof (for example, a human), chimeric cells as provided herein, or a cell line, a chimera cell line or a chromosomally-stable chimera as provided herein. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/940057 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/34 (20130101) Original (OR) Class A61K 35/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) C12N 5/0657 (20130101) C12N 5/0668 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071129 | Young et al. |
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| FUNDED BY |
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| APPLICANT(S) | Richard A. Young (Weston, Massachusetts); Peter B. Rahl (Natick, Massachusetts); James Bradner (Weston, Massachusetts) |
| ASSIGNEE(S) | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Richard A. Young (Weston, Massachusetts); Peter B. Rahl (Natick, Massachusetts); James Bradner (Weston, Massachusetts) |
| ABSTRACT | Disclosed herein are methods and compositions useful for inhibiting interaction between a bromodomain protein and an immunoglobulin (Ig) regulatory element. The methods and compositions are particularly useful for downregulating expression of an oncogene translocated with an Ig locus, as well as for treating a cancer (e.g., hematological malignancy) characterized by increased expression of an oncogene which is translocated with an Ig locus. Also disclosed herein are methods and assays for identifying agents that interfere with binding of bromodomain proteins to Ig regulatory elements, as well as methods and assays for identifying inhibitors of bromodomain. |
| FILED | Thursday, August 30, 2012 |
| APPL NO | 14/342265 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/551 (20130101) A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 38/02 (20130101) Original (OR) Class Peptides C07K 16/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 2500/02 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071130 | Conzen |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Suzanne D. Conzen (Chicago, Illinois) |
| ABSTRACT | Embodiments of the invention are directed to methods of treating cancer cells, particularly breast cancer cells, such as chemo-resistant cells, with an Hsp90 inhibitor and an anticancer agent or compound such as chemotherapy. |
| FILED | Friday, December 12, 2014 |
| APPL NO | 15/103187 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/4196 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 38/05 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 33/57434 (20130101) G01N 33/57492 (20130101) G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071143 | Badalamente et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Marie A. Badalamente (Mount Sinai, New York); Edward Wang (Poquott, New York) |
| ABSTRACT | Provided is a non-surgical method of treatment of carpal tunnel syndrome by administering an effective amount of purified collagenase I and II by injection onto a transverse carpal ligament, without penetrating the transverse carpal ligament. The purified collagenase I and II are obtained from Clostridium histolyticum, and the effective amount is a dose comprising a concentration of approximately 0.29 mg of the purified collagenase I and II to one ml diluent. |
| FILED | Tuesday, January 05, 2016 |
| APPL NO | 14/988205 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/74 (20130101) A61K 38/4886 (20130101) Original (OR) Class Enzymes C12Y 304/24003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071164 | Crew et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut); Arvinas, Inc. (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut); Arvinas, Inc. (New Haven, Connecticut) |
| INVENTOR(S) | Andrew Crew (Guilford, Connecticut); Craig Crews (New Haven, Connecticut); Hanqing Dong (Madison, Connecticut); Eunhwa Ko (New Haven, Connecticut); Jing Wang (Milford, Connecticut) |
| ABSTRACT | The present invention relates to bifunctional compounds, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins which are degraded and/or otherwise inhibited by bifunctional compounds according to the present invention. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand which binds to the ubiquitin ligase and on the other end a moiety which binds a target protein such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of targeted polypeptides. |
| FILED | Monday, August 10, 2015 |
| APPL NO | 14/822309 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 47/481 (20130101) Original (OR) Class A61K 47/48061 (20130101) Peptides C07K 5/0821 (20130101) C07K 5/06026 (20130101) C07K 5/06034 (20130101) C07K 5/06052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071172 | Gittes et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | George Gittes (Pittsburgh, Pennsylvania); Ping Guo (Cheswick, Pennsylvania); Xiangwei Xiao (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods are disclosed for producing pancreatic beta cells in a subject. The methods include administering to the subject a vector encoding heterologous Pancreas duodenal homeobox protein (Pdx) 1 and MafA, wherein the vector does not encode Neurogenin 3 (Ngn3) and wherein the subject is not administered any other nucleic acid encoding Ngn3. The vector is administered intraductally into a pancreatic duct of the subject. Compositions are disclosed that include a) a viral vector comprising a promoter operably linked to a nucleic acids encoding Pdx1 and a nucleic acid encoding MafA, wherein the vector does not encode Ngn3; b) a buffer; and c) a contrast dye for endoscopic retrograde cholangiopancreatography. These compositions are of use in any of the methods disclosed herein. |
| FILED | Friday, April 17, 2015 |
| APPL NO | 15/305083 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 48/0058 (20130101) A61K 48/0075 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071241 | Bhadra et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Niloy Bhadra (Cleveland Heights, Ohio); Kevin L. Kilgore (Avon Lake, Ohio); Narendra Bhadra (Chesterland, Ohio); Jesse Wainright (Willoughby Hills, Ohio); Tina Vrabec (Willoughby Hills, Ohio); Manfred Franke (South Euclid, Ohio) |
| ABSTRACT | Devices and methods for blocking signal transmission through neural tissue. One step of a method includes placing a therapy delivery device into electrical communication with the neural tissue. The therapy delivery device includes an electrode contact having a high charge capacity material. A multi-phase direct current (DC) can be applied to the neural tissue without damaging the neural tissue. The multi-phase DC includes a cathodic DC phase and anodic DC phase that collectively produce a neural block and reduce the charge delivered by the therapy delivery device. The DC delivery can be combined with high frequency alternating current (HFAC) block to produce a system that provides effective, safe, long term block without inducing an onset response. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/814817 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/06 (20130101) A61N 1/20 (20130101) A61N 1/0556 (20130101) Original (OR) Class A61N 1/36064 (20130101) A61N 1/36067 (20130101) A61N 1/36071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071257 | Efimov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Igor R. Efimov (Wildwood, Missouri); Valentin I. Krinski (Villeneuve Loubet, France); Vladmir P. Nikolski (St. Anthony, Minnesota) |
| ABSTRACT | A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a relatively low voltage electric field in such a way as to effectively unpin the anatomical reentry. Preferably, the relatively low voltage electric field is defined by at least one unpinning shock(s) that are lower than an expected lower limit of vulnerability as established, for example, by a defibrillation threshold test. By understanding the physics of the electric field distribution between cardiac cells, the method permits the delivery of an electric field sufficient to unpin the core of the anatomical reentry, whether the precise or estimated location of the reentry is known or unknown and without the risk of inducting ventricular fibrillation. A number of embodiments for performing the method are disclosed. |
| FILED | Monday, March 06, 2017 |
| APPL NO | 15/450334 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0402 (20130101) A61B 5/0464 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3925 (20130101) A61N 1/3962 (20130101) A61N 1/3987 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071266 | Cain |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Charles A. Cain (Ann Arbor, Michigan) |
| ABSTRACT | A medical imaging and therapy device is provided that may include any of a number of features. The device may include a Histotripsy transducer, a generator and controller configured to deliver Histotripsy energy from the transducer to target tissue, and an imaging system. In some embodiments, a method of treating tissue with Histotripsy energy comprises positioning a focus of a histotripsy transducer on a target tissue, delivering histotripsy energy from the histotripsy transducer through a bone aberrator, forming a histotripsy bubble cloud on the focus, and preventing the formation of secondary histotripsy bubble clouds without implementing an aberration correction algorithm. |
| FILED | Thursday, September 03, 2015 |
| APPL NO | 14/845059 |
| ART UNIT | 3739 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/13 (20130101) A61B 8/0816 (20130101) A61B 17/320068 (20130101) A61B 2018/00642 (20130101) A61B 2018/00702 (20130101) A61B 2090/378 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 7/02 (20130101) A61N 2007/003 (20130101) A61N 2007/0039 (20130101) A61N 2007/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071943 | Scott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Peter J. H. Scott (Ypsilanti, Michigan); Melanie S. Sanford (Ann Arbor, Michigan); Naoko Ichiishi (Ann Arbor, Michigan); Allen F. Brooks (Ann Arbor, Michigan); Melissa Rodnick (Ann Arbor, Michigan); Joseph J. Topczewski (Ann Arbor, Michigan) |
| ABSTRACT | Copper-catalyzed radiofluorination of iodonium salts, iodonium salts, and compounds obtained by copper-catalyzed radiofluorination of iodonium salts are disclosed. Diagnostic and therapeutic methods involving such compounds also are disclosed. |
| FILED | Friday, April 10, 2015 |
| APPL NO | 15/303087 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/04 (20130101) A61K 51/0402 (20130101) A61K 51/0493 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/00 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 17/361 (20130101) C07C 41/22 (20130101) Original (OR) Class C07C 41/22 (20130101) C07C 43/225 (20130101) C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 47/55 (20130101) C07C 51/363 (20130101) C07C 67/307 (20130101) C07C 67/307 (20130101) C07C 69/76 (20130101) C07C 231/12 (20130101) C07C 231/12 (20130101) C07C 231/12 (20130101) C07C 233/15 (20130101) C07C 233/51 (20130101) C07C 233/51 (20130101) Steroids C07J 1/0066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071945 | Neckers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jane B. Neckers (Bethesda, Maryland); Yeong Sang Kim (Gaithersburg, Maryland); Sunmin Lee (Boyds, Maryland); Vineet Kumar (Rockville, Maryland); Sanjay V. Malhotra (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Jane B. Neckers (Bethesda, Maryland); Yeong Sang Kim (Gaithersburg, Maryland); Sunmin Lee (Boyds, Maryland); Vineet Kumar (Rockville, Maryland); Sanjay V. Malhotra (Rockville, Maryland) |
| ABSTRACT | Disclosed are compounds which are nuclear receptor modulators that can act as antagonists to the androgen receptor, for example, a compound of Formula I: wherein R1 to R5 and X1 to X5 are as described herein, as well as pharmaceutically acceptable salts, solvates, and stereoisomers thereof. Pharmaceutical compositions comprising such compounds, as well as methods of use, and treatment for cancers, including prostate cancers, other nuclear receptor mediated cancers, and other conditions, are also disclosed. |
| FILED | Friday, June 15, 2012 |
| APPL NO | 14/126178 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/12 (20130101) A61K 31/275 (20130101) A61K 31/275 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 49/80 (20130101) C07C 49/84 (20130101) C07C 49/796 (20130101) Original (OR) Class C07C 49/813 (20130101) C07C 205/45 (20130101) C07C 255/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071953 | Penning et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Trevor M. Penning (Springfield, Pennsylvania); Adegoke O. Adeniji (Drexel Hill, Pennsylvania); Michael C. Byrns (Philadelphia, Pennsylvania); Jeffrey Winkler (Wynnewood, Pennsylvania); Barry Twenter (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention includes compositions comprising selective AKR1C3 inhibitors. The invention also includes compositions comprising bifunctional AKR1C3 inhibitors and selective androgen receptor modulators. The invention further includes methods of treatment using the compositions of the invention. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 14/993742 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) A61K 31/195 (20130101) A61K 31/196 (20130101) A61K 31/205 (20130101) A61K 31/205 (20130101) A61K 31/405 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 229/58 (20130101) Original (OR) Class C07C 229/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071962 | Yan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | British Columbia Cancer Agency Branch (Vancouver, Canada); The University of British Columbia (Vancouver, Canada) |
| ASSIGNEE(S) | British Columbia Cancer Agency Branch (Vancouver, Canada); The University of British Columbia (Vancouver, Canada) |
| INVENTOR(S) | Luping Yan (Vancouver, Canada); Raymond J. Andersen (Vancouver, Canada); Marianne Dorothy Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Carmen Adriana Banuelos (Richmond, Canada) |
| ABSTRACT | Compounds having a structure of Structure I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R4, R6, Y1 and Y2 are as defined herein, and wherein at least one of R3 or R4 is a straight-chain C1-C6 haloalkyl, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/626526 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4015 (20130101) Heterocyclic Compounds C07D 207/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071965 | Tonge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Peter Tonge (Setauket, New York); Pan Pan (Stony Brook, New York) |
| ABSTRACT | The present invention provides novel 2-pyridone compounds and 4-pyridone compounds and methods of treating a subject infected with a pathogen of Staphylococcus aureus, Mycobacterium tuberculosis, Francisella tularensis, Burkholderia pseudomallei, Yersinia pestis, Escherichia coli and Proteus mirabilisone. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/130365 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/64 (20130101) C07D 213/69 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071990 | Tuttle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Susan Bane Tuttle (Vestal, New York); Kamalika Mukherjee (Binghamton, New York) |
| ABSTRACT | A technique is provided to visualize microtubules in live cells that does not require genetic manipulation or microinjection. Moreover, this method also avoids perturbation of the endogenous microtubule network that occurs with taxol treatment. This technique exploits tyrosination and detyrosination of tubulin, a posttranslational modification cycle specific to the C-terminus of α-tubulin. Specifically, cells are grown in medium supplemented with a tyrosine derivative possessing a reactive functional group. The cellular enzyme tubulin tyrosine ligase attaches the unnatural amino acid to a single site on tubulin. Addition of fresh medium containing a suitably derivatized fluorophore then yields fluorescent tubulin, which incorporate into cellular microtubules. Importantly, the tubulin labeling approach demonstrated here does not detrimentally affect microtubule network or cell morphology. Thus we present a simple, robust labeling technique that allows microscopic analysis of microtubules in live cells. |
| FILED | Monday, June 02, 2014 |
| APPL NO | 14/293417 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Heterocyclic Compounds C07D 405/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072016 | Petrukhin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Albany, New York); Graham Johnson (Sanbornton, New Hampshire); Rando Allikmets (Cornwall on Hudson, New York); Emily Freeman (Albany, New York); Ping Chen (Albany, New York); Michael Conlon (Albany, New York); Lei Zhu (Albany, New York) |
| ABSTRACT | The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl, wherein two or more of R1, R2, R3, R4, or R5 are other than H; R6 is H, OH, or halogen; and B is a substituted or unsubstituted heterobicycle, wherein when R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is H, R2 is CF3, R3 is H, R4 is CF3, and R5 is H, or R1 is Cl, R2 is H, R3 is H, R4 is F, and R5 is H, or R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is CF3, R2 is F, R3 is H, R4 is H, and R5 is H, or R1 is Cl, R2 is F, R3 is H, R4 is H, and R5 is H, then B is other than or a pharmaceutically acceptable salt thereof. |
| FILED | Monday, October 02, 2017 |
| APPL NO | 15/722760 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072022 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Jia Zhou (League City, Texas); Chunyong Ding (Galveston, Texas); Qiang Shen (Houston, Texas) |
| ABSTRACT | Certain embodiments are directed to oridonin analogs or derivatives. In certain aspects, the derivatives are used as anticancer or anti-inflammatory agents. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 15/635454 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 311/78 (20130101) C07D 405/04 (20130101) C07D 491/08 (20130101) C07D 493/08 (20130101) C07D 493/18 (20130101) Original (OR) Class C07D 498/08 (20130101) C07D 513/08 (20130101) C07D 515/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072028 | Burke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Martin D. Burke (Champaign, Illinois); Pulin Wang (Austin, Texas); Ian Crouch (Urbana, Illinois) |
| ABSTRACT | Provided are methods for site- and stereo-retentive cross-couplings with unactivated secondary boronic acids, which methods are particularly useful in building block-based approach for small molecule synthesis. Also provided is a method of forming an air-stable chiral secondary boronic acid. |
| FILED | Monday, November 03, 2014 |
| APPL NO | 15/034102 |
| ART UNIT | 1671 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 37/04 (20130101) C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 1/321 (20130101) C07C 1/321 (20130101) C07C 1/321 (20130101) C07C 1/321 (20130101) C07C 1/321 (20130101) C07C 13/28 (20130101) C07C 15/02 (20130101) C07C 15/14 (20130101) C07C 15/24 (20130101) C07C 67/343 (20130101) C07C 67/343 (20130101) C07C 69/76 (20130101) C07C 2523/50 (20130101) C07C 2531/24 (20130101) C07C 2601/02 (20170501) C07C 2601/04 (20170501) C07C 2601/08 (20170501) C07C 2601/14 (20170501) C07C 2601/16 (20170501) C07C 2602/10 (20170501) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072043 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Zhong-Yin Zhang (Carmel, Indiana); Sheng Zhang (Carmel, Indiana) |
| ABSTRACT | Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 14/975232 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/0812 (20130101) Original (OR) Class C07K 5/06078 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/42 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 2333/916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072047 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania); Baruch S. Blumberg Institute (Doylestown, Pennsylvania); Hoffmann-La Roche Inc. (Little Falls, New Jersey) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania); Baruch S. Blumberg Institute (Doylestown, Pennsylvania); Hoffmann-La Roche Inc. (Little Falls, New Jersey) |
| INVENTOR(S) | Haitao Guo (Carmel, Indiana); Dawei Cai (Indianapolis, Indiana); Andrea Cuconati (Oreland, Pennsylvania); Changhua Ji (Shanghai, China PRC) |
| ABSTRACT | The present invention relates to methods and uses for screening anti-hepadnaviral substances, wherein the substances are screened for the capacity to inhibit covalently closed circular (ccc) DNA of a hepadnavirus, like hepatitis B virus. The methods and uses take advantage of cells comprising a nucleic sequence encoding a tagged hepadnavirus e antigen, like Hepatitis B virus e antigen (HBeAg). Furthermore, the present invention provides nucleic acid sequences encoding a tagged hepadnavirus e antigen and proteins encoded thereby. Also kits for use in the screening methods are provided. |
| FILED | Friday, June 19, 2015 |
| APPL NO | 15/309680 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/40 (20130101) C07K 2319/42 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2730/10122 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 2333/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072049 | Hong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Chang Soo Hong (Chicago, Illinois); Tohru Yamada (Oak Park, Illinois); Arsenio M. Fialho (Lisbon, Portugal); Tapas K. Das Gupta (River Forest, Illinois); Ananda M. Chakrabarty (Villa Park, Illinois) |
| ABSTRACT | The present invention discloses methods and materials for delivering a cargo compound into a brain cancer cell and/or across the blood-brain barrier. Delivery of the cargo compound is accomplished by the use of protein transport peptides derived from Neisseria outer membrane proteins, such as Laz. The invention also provides synthetic transit peptides comprised of the pentapeptide AAEAP. The invention further discloses methods for treating cancer, and specifically brain cancer, as well as other brain-related conditions. Further, the invention provides methods of imaging and diagnosing cancer, particular brain cancer. |
| FILED | Monday, April 11, 2016 |
| APPL NO | 15/095808 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/64 (20170801) Peptides C07K 14/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072054 | Kalyanasundaram |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Ramaswamy Kalyanasundaram (Rockford, Illinois) |
| ABSTRACT | The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy. |
| FILED | Tuesday, July 14, 2015 |
| APPL NO | 14/798945 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0003 (20130101) A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/4354 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0065 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2333/4353 (20130101) G01N 2469/10 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072058 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Baozhong Wang (Dultuh, Georgia); Richard W. Compans (Atlanta, Georgia); Jacques Galipeau (Atlanta, Georgia); Jiusheng Deng (Snellville, Georgia) |
| ABSTRACT | This disclosure relates to a GM-CSF and IL-4 conjugate fused to a glycolipid (GPI)-anchoring sequence that is incorporated into chimeric virus-like particles (VLPs) enriched with a viral protein, e.g., viral envelope protein or HIV envelope protein. In certain embodiments, the disclosure relates to methods of immunization with the chimeric VLPs disclosed herein. In certain embodiments, the disclosure relates to methods of immunization with disclosed HIV antigen containing VLPs through an intramuscular priming-intranasal boosting immunization route. |
| FILED | Friday, April 29, 2016 |
| APPL NO | 15/142169 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/543 (20130101) A61K 2039/575 (20130101) A61K 2039/5258 (20130101) A61K 2039/55522 (20130101) A61K 2039/55527 (20130101) Peptides C07K 14/005 (20130101) C07K 14/435 (20130101) C07K 14/535 (20130101) C07K 14/5406 (20130101) Original (OR) Class C07K 14/70596 (20130101) C07K 16/1063 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2319/035 (20130101) C07K 2319/912 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/79 (20130101) C12N 2740/16023 (20130101) C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072060 | Raleigh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Daniel Raleigh (Stony Brook, New York); Hui Wang (East Setauket, New York); Ping Cao (New York, New York); Andisheh Abedini (New York, New York) |
| ABSTRACT | Isolated non-naturally occurring, mutant-human islet amyloid polypeptides (hIAPP) are disclosed. These polypeptides can be formulated or co-formulated at physiological pH, which enable the polypeptides of the instant disclosure to be delivered to a subject having an amyloid-based disease in a single injection with an insulin agent. Methods and compositions for treating amyloid-based disease in a subject in need thereof, by administering an effective amount of an isolated, mutant-hIAPP polypeptide, including formulations or co-formulations thereof are also disclosed. |
| FILED | Friday, May 01, 2015 |
| APPL NO | 15/308138 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/22 (20130101) A61K 38/28 (20130101) A61K 38/28 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/001 (20130101) C07K 14/575 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072061 | Spitzer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dirk Spitzer (Webster Groves, Missouri); William G Hawkins (Olivette, Missouri) |
| ASSIGNEE(S) | Washington University (Saint Louis, Missouri) |
| INVENTOR(S) | Dirk Spitzer (Webster Groves, Missouri); William G Hawkins (Olivette, Missouri) |
| ABSTRACT | Fusion polypeptides comprising a TRAIL trimer and a targeting domain are disclosed. The targeting domain can be, in some embodiments, a sequence that binds MUC16, which is prevalent on some tumor cells such as pancreatic and ovarian tumor cells. A sequence that binds MUC 16 can be mesothelin or a MUC16-binding fragment thereof, such as amino acids 1-64 of mesothelin. A fusion polypeptide of the present teachings can induce apoptosis in a target cell such as a MUC16-expressing cancer cell. Also disclosed are nucleic acids encoding the fusion polypeptides, and methods of use of the fusion polypeptides and nucleic acids. |
| FILED | Wednesday, October 11, 2017 |
| APPL NO | 15/730441 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) A61K 38/177 (20130101) A61K 38/191 (20130101) A61K 38/1761 (20130101) A61K 38/1764 (20130101) Peptides C07K 14/525 (20130101) C07K 14/705 (20130101) Original (OR) Class C07K 14/4747 (20130101) C07K 14/4748 (20130101) C07K 14/70575 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/33 (20130101) C07K 2319/43 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/74 (20130101) C12N 15/79 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072064 | Stone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Geoffrey W. Stone (Coral Gables, Florida); Richard S. Kornbluth (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Geoffrey W. Stone (Coral Gables, Florida); Richard S. Kornbluth (La Jolla, California) |
| ABSTRACT | The invention provides fusion proteins comprising antigens of infectious disease agents and cancer cells linked to multiple-trimer forms of TNF SuperFamily (TNFSF) ligands. The TNFSFs serve as vaccine adjuvants for increasing the immune response to the antigens. In particular, a fusion polypeptide strand that self-assembles inside cells into a multiple-trimer form of CD40 ligand (CD40L, TNFSF5) is provided. Other similar fusion proteins are also disclosed. The fusion proteins can be delivered to a host as isolated proteins, as nucleic acids used directly in DNA vaccination or carried and expressed by a viral vector such as adenovirus. In addition to use as a vaccine to prevent or ameliorate disease caused by an infectious agent, compositions of the invention may be used for the treatment of ongoing infection or for cancer immunotherapy. |
| FILED | Sunday, March 16, 2014 |
| APPL NO | 14/776609 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/00 (20130101) A61K 39/0011 (20130101) A61K 39/21 (20130101) A61K 2039/53 (20130101) A61K 2039/645 (20130101) A61K 2039/5154 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/005 (20130101) C07K 14/705 (20130101) C07K 14/785 (20130101) C07K 14/70575 (20130101) Original (OR) Class C07K 2319/30 (20130101) C07K 2319/33 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072067 | Malik |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Punam Malik (Cincinnati, Ohio) |
| ABSTRACT | Methods and compositions disclosed herein generally relates to methods of determining minimum hematopoietic stem cell (HSC) chimerism and gene dosage for correction of a hematopoietic disease; in particular, in in vivo models. The invention also relates to modified lentiviral expression vectors for increasing a viral titer and various methods for increasing such titers as well as expression vectors capable of enhancing such titers. The invention also relates to CHS4 chromatin insulator-derived functional insulator sequences. The invention also relates to methods for genetic correction of diseases or reducing symptoms thereof, such as sickle cell anemia or β-thalassemia. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 15/115530 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/805 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/10043 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072070 | Wan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Hongquan Wan (Rockville, Maryland); Maryna C. Eichelberger (Silver Spring, Maryland); Hua Yang (City Johns Creek, Georgia); James Stevens (Lilburn, Georgia); David A. Shore (Decatur, Georgia); Rebecca J. Garten (Decatur, Georgia) |
| ABSTRACT | Isolated monoclonal antibodies and antigen binding fragments thereof that specifically bind neuraminidase (NA) of an N1 subtype influenza virus are disclosed herein. These antibodies and antigen binding fragments can be used for the detection of an N1 subtype influenza virus and for determining the immunogenicity of vaccines. The antibodies and antigen binding fragments also can be used for the treatment of a subject to prevent or ameliorate an influenza infection. |
| FILED | Thursday, December 03, 2015 |
| APPL NO | 15/532059 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/40 (20130101) C07K 16/1018 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) Enzymes C12Y 302/01018 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/6878 (20130101) G01N 33/56983 (20130101) G01N 2333/11 (20130101) G01N 2333/924 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072078 | Orentas et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Rimas J. Orentas (Washington, District of Columbia); Ira H. Pastan (Potomac, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Crystal L. Mackall (Bethesda, Maryland) |
| ABSTRACT | The invention provides a chimeric antigen receptor (CAR) comprising an antigen binding domain comprising SEQ ID NOs: 1-6, a transmembrane domain, and an intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. |
| FILED | Wednesday, September 18, 2013 |
| APPL NO | 14/437889 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 16/3061 (20130101) C07K 2319/03 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 2501/505 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072084 | Bigner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (Washington, District of Columbia) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); The United States of America as Represented by the Secretary Department of Health and Human Services (NIH) (Washington, District of Columbia) |
| INVENTOR(S) | Darell D. Bigner (Mebane, North Carolina); Chien-Tsun Kuan (Cary, North Carolina); Ira H. Pastan (Potomac, Maryland); Charles Pegram (Durham, North Carolina) |
| ABSTRACT | We tested the in vitro and in vivo efficacy of a recombinant bispecific immunotoxin that recognizes both EGFRwt and tumor-specific EGFRvIII receptors. A single chain antibody was cloned from a hybridoma and fused to toxin, carrying a C-terminal peptide which increases retention within cells. The binding affinity and specificity of the recombinant bispecific immunotoxin for the EGFRwt and the EGFRvIII proteins was measured. In vitro cytotoxicity was measured. In vivo activity of the recombinant bispecific immunotoxin was evaluated in subcutaneous models and compared to that of an established monospecific immunotoxin. In our preclinical studies, the bispecific recombinant immunotoxin, exhibited significant potential for treating brain tumors. |
| FILED | Tuesday, October 11, 2016 |
| APPL NO | 15/290040 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/39558 (20130101) A61K 47/6829 (20170801) A61K 47/6849 (20170801) A61K 2039/505 (20130101) A61K 2039/545 (20130101) Peptides C07K 14/21 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/56 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2317/624 (20130101) C07K 2319/04 (20130101) C07K 2319/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072091 | Weissman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Irving L. Weissman (Stanford, California); Agnieszka Czechowicz (Menlo Park, California); Deepta Bhattacharya (San Francisco, California); Daniel Kraft (Portola Valley, California) |
| ABSTRACT | The present invention provides a clinically applicable method of stem cell transplantation that facilitates engraftment and reconstitutes immunocompetence of the recipient without requiring radiotherapy or chemotherapy, and without development of GVHD or graft rejection. Aspects of the present invention are based on the discovery that the depletion of the endogenous stem cell niche facilitates efficient engraftment of stem cells into that niche. In particular, the present invention combines the use of selective ablation of endogenous stem cells, in combination with the administration to the recipient of exogenous stem cells, resulting in efficient, long-term engraftment and tolerance. |
| FILED | Friday, July 15, 2016 |
| APPL NO | 15/211679 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 39/3955 (20130101) A61K 2039/54 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/32 (20130101) C07K 16/2803 (20130101) C07K 16/2812 (20130101) C07K 16/2815 (20130101) C07K 16/2866 (20130101) C07K 16/2896 (20130101) Original (OR) Class C07K 2317/73 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072246 | Yee et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | The Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Cassian Yee (Seattle, Washington); Yongqing Li (Shoreline, Washington) |
| ABSTRACT | A method of carrying out adoptive immunotherapy by administering a subject an antigen-specific cytotoxic T lymphocytes (CTL) preparation in a treatment-effective amount is described. In the method, the CTL preparation is preferably administered as a preparation of an in vitro antigen-stimulated and expanded primate CTL population, the CTL population: (i) depleted of FoxP3+ T lymphocytes prior to antigen stimulation; (ii) antigen-stimulated in vitro in the presence of interleukin-21; or (iii) both depleted of FoxP3+ T lymphocytes prior to antigen stimulation and then antigen-stimulated in vitro in the presence of interleukin-21. Methods of preparing such compositions, and compositions useful for carrying out the adoptive immunotherapy, are also described. |
| FILED | Tuesday, June 21, 2016 |
| APPL NO | 15/188096 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/41 (20130101) A61K 35/12 (20130101) A61K 35/17 (20130101) A61K 39/00 (20130101) A61K 2035/124 (20130101) A61K 2039/51 (20130101) A61K 2039/5154 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) Original (OR) Class C12N 2501/23 (20130101) C12N 2501/998 (20130101) C12N 2501/2321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072257 | Bhatia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Sangeeta N. Bhatia (Lexington, Massachusetts); Kelly R. Stevens (Cambridge, Massachusetts) |
| ABSTRACT | The invention features an “inverse patterning” or “Intaglio-Void/Embed-Relief Topographic (In VERT) molding” manufacturing process for generating high-resolution three-dimensional (3D) multi-cellular microstructures in distinct cellular compartments of a single hydrogel. The platform has general utility in the development of engineered tissues for human therapies, drug testing, and disease models. Additionally, the platform can serve as a model system for studying 3D cell-cell interactions in fields as diverse as stem cell biology to the development of cancer therapeutics. |
| FILED | Thursday, February 28, 2013 |
| APPL NO | 14/381866 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0062 (20130101) C12N 5/0671 (20130101) C12N 11/04 (20130101) Original (OR) Class C12N 11/08 (20130101) C12N 11/10 (20130101) C12N 2533/76 (20130101) C12N 2535/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072264 | Davidson et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Beverly L. Davidson (Iowa City, Iowa); Haibin Xia (Iowa City, Iowa); Qinwen Mao (Iowa City, Iowa); Henry Paulson (Iowa City, Iowa); Ryan Boudreau (Iowa City, Iowa); Scott Harper (Iowa City, Iowa) |
| ABSTRACT | The present invention is directed to small interfering RNA molecules (siRNA) targeted against nucleic acid sequence that encodes huntingtin or ataxin-1, and methods of using these siRNA molecules. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/395993 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/05 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/53 (20130101) C12N 2310/111 (20130101) C12N 2310/531 (20130101) C12N 2750/14143 (20130101) C12N 2799/021 (20130101) C12N 2799/022 (20130101) C12N 2799/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072282 | Lin |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Hening Lin (Ithaca, New York) |
| ABSTRACT | Method for identifying a modulator of Sirt6, PfSir2a, or Sirt7 deacylase activity, wherein a fatty-acylated substrate containing an acyl-lysine moiety and an indicator moiety is contacted with Sirt6, PfSir2a, or Sirt7 in the presence of a candidate compound under conditions for Sirt6, PfSir2a, or Sirt7 to deacylate the substrate, wherein the acyl is a hydrophobic fatty acyl group containing a hydrocarbon group having at least three carbon atoms connected by carbon-carbon bonds; contacting the deacylated substrate with a cleavage agent that cleaves the linkage between the lysine and indicator moiety to generate a detectable signal; and correlating a quantified Sirt6, PfSir2a, or Sirt7 deacylase activity therefrom. Modulating compounds of Sirt6, PfSir2a, or Sirt7 deacylase activity are also described, as are pharmaceutical compositions thereof, methods of treatment by administration of the modulating compounds, and kits for practicing the method. |
| FILED | Thursday, January 21, 2016 |
| APPL NO | 15/002790 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 327/42 (20130101) Peptides C07K 5/1019 (20130101) C07K 7/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) C12Q 1/48 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/98 (20130101) G01N 2333/91091 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072283 | Myllykangas et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Samuel Myllykangas (Espoo, Finland); Jason D. Buenrostro (Palo Alto, California); Hanlee P. Ji (Stanford, California) |
| ABSTRACT | Certain embodiments provide a method for capturing a genomic fragment. The method may comprise: obtaining a substrate comprising a first population of surface-bound oligonucleotides and a second population of surface-bound oligonucleotides; hybridizing a first member of the first population of surface-bound oligonucleotides to a selection oligonucleotide comprising a region that hybridizes with the first member and a region that contains a genomic sequence; extending the first member of the first population of surface-bound oligonucleotides to produce a support-bound selection primer that comprises a sequence that is complementary to the genomic sequence; hybridizing the support-bound selection primer to a nucleic acid fragment comprising the genomic sequence; extending the support-bound selection primer to produce an extension product that contains a sequence that flanks the genomic sequence, e.g., in a genome; and amplifying the extension product on the substrate. |
| FILED | Monday, June 09, 2014 |
| APPL NO | 14/300048 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 1/6874 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2565/518 (20130101) C12Q 2565/518 (20130101) C12Q 2565/518 (20130101) C12Q 2565/537 (20130101) C12Q 2565/537 (20130101) C12Q 2565/537 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072292 | Matsunami et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Hiroaki Matsunami (Durham, North Carolina); Yun Li (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to polypeptides capable of modulating odorant receptor activation. In particular, the present invention provides polypeptides (e.g., type 3 muscarinic actetylcholine receptor M3) capable of enhancing odorant receptor activation. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for polypeptide polymorphisms and mutations associated with odorant receptor activation (e.g., polymorphisms and mutations associated with muscarinic actetylcholine receptor polypeptides (e.g., M1, M2, M3, M4, M5)), as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins. |
| FILED | Monday, April 03, 2017 |
| APPL NO | 15/477873 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/70571 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072297 | Wong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David T. W. Wong (Beverly Hills, California); Maie A. R. St. John (Los Angeles, California); Yang Li (Los Angeles, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | David T. W. Wong (Beverly Hills, California); Maie A. R. St. John (Los Angeles, California); Yang Li (Los Angeles, California) |
| ABSTRACT | A method to detect a biomarker in saliva wherein the biomarker is an extracellular mRNA, comprises detecting the extracellular mRNA in the cell-free saliva; transcriptome analysis of saliva comprises detecting a transcriptome pattern in the cell-free saliva; a method to detect genetic alterations in an organ or in a gene in the organ by analyzing saliva, comprises detecting a transcriptome pattern and/or the mRNA profiling of the gene in cell-free saliva; a method to diagnose an oral or systemic pathology disease or disorder in a subject, comprises: detecting profile of a biomarker associated with the pathology disease or disorder, in particular mRNA and/or protein, in cell-free saliva and/or serum; kits comprising identifier for at least one biomarker for performing at least one of the methods; and use of salivary biomarker salivary and/or serum mRNAs as biomarkers for oral and/or systemic pathology, disease or disorder. |
| FILED | Thursday, February 17, 2005 |
| APPL NO | 10/589788 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072305 | Wolff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Bernard Wolff (Roswell, Georgia); Jonas M. Winchell (Lilburn, Georgia); Maureen Diaz (Atlanta, Georgia) |
| ABSTRACT | Disclosed herein are methods for detecting presence of one or more of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Toxoplasma gondii, Moraxella catarrhalis, Escherichia coli, Shigella, Staphylococcus aureus, Pneumocystis jirovecii, Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Ureaplasma spp., Bartonella spp., Streptococcus agalactiae, and Neisseria meningitidis nucleic acids in a sample, such as a biological sample obtained from a subject, or an environmental sample. This disclosure also provides probes, primers, and kits for detecting one or more of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Toxoplasma gondii, Moraxella catarrhalis, Escherichia coli, Shigella, Staphylococcus aureus, Pneumocystis jirovecii, Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Ureaplasma spp., Bartonella spp., Streptococcus agalactiae, and Neisseria meningitidis in a sample. |
| FILED | Wednesday, February 27, 2013 |
| APPL NO | 14/398390 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6895 (20130101) C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072924 | Boyle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | John J. Boyle (St. Louis, Missouri); Guy M. Genin (St. Louis, Missouri); Maiko Kume (St. Louis, Missouri); Robert B. Pless (St. Louis, Missouri); Stavros Thomopoulos (St. Louis, Missouri) |
| ABSTRACT | A computer-implemented method for determining a quantification of the deformation of the sample is implemented using a computer device in communication with a memory. The method includes receiving, by the computer device, a first image of the sample and a second image of the sample. The method also includes registering the first image to the second image using a warping function. The warping function maps a plurality of pixels in the first image to a plurality of pixels in the second image. A first displacement field for the sample is determined based on the warping function, where the first displacement field includes at least a portion of the warping function. A first quantification of the deformation of the sample is determined based at least in part on the displacement field. |
| FILED | Tuesday, March 17, 2015 |
| APPL NO | 15/126852 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/30 (20170101) G06T 2207/10004 (20130101) G06T 2207/30024 (20130101) G06T 2207/30108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073035 | Zhuang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaowei Zhuang (Lexington, Massachusetts); Wilfred M. Bates (Gottingen, Germany); Michael J. Rust (Medford, Massachusetts) |
| ABSTRACT | The present invention generally relates to sub-diffraction limit image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The entities may be immobilized relative to each other and/or to a common entity. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction limit resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA, a protein, a cell, a tissue, etc. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction limit image resolution, computer programs and techniques for sub-diffraction limit image resolution, methods for promoting sub-diffraction limit image resolution, methods for producing photoswitchable entities, and the like. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/252307 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) C09K 2211/1044 (20130101) C09K 2211/1475 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1475 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 33/582 (20130101) G01N 2015/0065 (20130101) G01N 2021/6421 (20130101) G01N 2021/6439 (20130101) G01N 2021/6441 (20130101) G01N 2201/12 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074173 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Michael I. Miller (Pikesville, Maryland); Susumu Mori (Ellicott City, Maryland) |
| ABSTRACT | A method, computer system and computer readable storage medium for searching for one or more images having a region of interest similar to the region of a subject, including: receiving imaging data comprising a plurality of image elements of the region of interest of the subject; segmenting the imaging data of the region of interest of the subject into a plurality of sub-regions corresponding to various structures at a plurality of levels of granularity, the plurality of levels of granularity having a relationship such that a level of granularity has fewer structures at a lower level of granularity; and calculating at each of the plurality of levels of granularity an abnormality factor or risk factor for the segmented various structures of said region of interest, to provide a segmented said region of interest of said subject with at least one of said abnormality factor or risk factor associated therewith. |
| FILED | Monday, December 08, 2014 |
| APPL NO | 15/101820 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0037 (20130101) A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 8/08 (20130101) A61B 2576/026 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/10132 (20130101) G06T 2207/10136 (20130101) G06T 2207/20128 (20130101) G06T 2207/30008 (20130101) G06T 2207/30016 (20130101) G06T 2207/30048 (20130101) G06T 2207/30056 (20130101) G06T 2207/30061 (20130101) G06T 2207/30088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074751 | Park et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (Gyeonggi-do, South Korea) |
| ASSIGNEE(S) | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (Ansan-si, South Korea) |
| INVENTOR(S) | Tae Joo Park (Gwangju, South Korea); Dae Woong Kim (Gyeonggi-do, South Korea) |
| ABSTRACT | A solar cell is provided. The solar cell includes a first semiconductor layer of a first conductivity type, a second semiconductor layer of a second conductivity type disposed on the first semiconductor layer, an anti-reflection layer on the second semiconductor layer, and a negative charge layer between the anti-reflection layer and the second semiconductor layer. |
| FILED | Tuesday, October 13, 2015 |
| APPL NO | 14/881391 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/068 (20130101) H01L 31/02167 (20130101) H01L 31/02168 (20130101) Original (OR) Class H01L 31/02366 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10071076 | Kridel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Steven J. Kridel (Clemmons, North Carolina); W. Todd Lowther (Pfafftown, North Carolina); Herman H. Odens (Ooltewah, Tennessee); Jeffrey D. Schmitt (Asheville, North Carolina) |
| ABSTRACT | Active compounds useful for inhibiting fatty acid synthase in a subject in need thereof are described. The active compounds are, in general, a 5-mercapto-1H-Indazole-4,7-dione or an analog thereof. The compounds are useful for treating subjects afflicted with, cancer, obesity, diabetes, a viral infection, a bacterial infection, a fungal infection, or a protozoal infection. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 15/193793 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/416 (20130101) Original (OR) Class Heterocyclic Compounds C07D 231/56 (20130101) C07D 261/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071798 | Zhong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiaolin Zhong (Calabasas, California); Kahei Danny Fong (Los Angeles, California); Xiaowen Wang (Culver City, California) |
| ABSTRACT | A novel passive control technique for laminar flow over air transportation vehicles and space reentry vehicles flying at high supersonic and hypersonic speeds is disclosed. The control of laminar flow can be achieved by applying an array of surface roughness elements in the region before the laminar-turbulent transition. For example, an array of two-dimensional rings, stripes, or closely packed three-dimensional isolated roughness elements may be used to stabilize the instability waves and delay transition. The roughness elements may have a height between 40% and 60% of the local boundary-layer thickness. The exact location, height, and spacing of surface roughness elements may be determined by a numerical simulation strategy based on the most unstable second mode, e.g. using known eN transition prediction method, experimental measurement, or any other suitable technique. |
| FILED | Tuesday, November 19, 2013 |
| APPL NO | 14/443992 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 21/10 (20130101) Original (OR) Class B64C 30/00 (20130101) B64C 2230/26 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/08 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072334 | Tong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KLA-Tencor Corporation (Milpitas, California); UChicago Argonne LLC (Chicago, Illinois) |
| ASSIGNEE(S) | KLA-Tencor Corporation (Milpitas, California); UChicago Argonne LLC (Chicago, Illinois) |
| INVENTOR(S) | William M. Tong (San Francisco, California); Alan D. Brodie (Palo Alto, California); Jeffrey Elam (Elmhurst, Illinois); Anil Mane (Naperville, Illinois) |
| ABSTRACT | A digital pattern generator has a MEMS substrate with a plurality of doping layers and a plurality of insulating layers between respective doping layers. A plurality of lenslets are formed as holes through the substrate. A charge drain coating is applied to the inner surfaces of the lenslets. The charge drain coating drains electrons that come into contact with the charge drain coating so that the performance of the digital pattern generator will not be hindered by electron charge build-up. The charge drain coating includes a doping material that coalesces into clusters that are embedded within a high dielectric insulating material. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/786358 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0008 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/32 (20130101) C23C 16/34 (20130101) C23C 16/40 (20130101) C23C 16/402 (20130101) C23C 16/403 (20130101) C23C 16/405 (20130101) C23C 16/45529 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/12 (20130101) H01J 37/026 (20130101) H01J 37/3174 (20130101) H01J 2237/1205 (20130101) H01J 2237/31794 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072347 | Woodrow |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Thomas A. Woodrow (Lakeside, Texas) |
| ABSTRACT | Systems and methods for tin antimony plating are provided. One plating method includes doping a tin (Sn) plating solution with antimony (Sb). One method also includes electroplating a component using the antimony-doped tin plating. The antimony-doped tin plating formed by one method includes between about 1% and about 3% antimony. |
| FILED | Friday, October 05, 2012 |
| APPL NO | 13/646401 |
| ART UNIT | 1754 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/32 (20130101) C25D 3/60 (20130101) Original (OR) Class C25D 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072516 | Carr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Jesse M. Carr (Hartford, Connecticut); Bryan P. Dube (Columbia, Connecticut) |
| ABSTRACT | A vane arc segment includes a radially inner and outer platforms and an airfoil mechanically clamped between the platforms. The airfoil has an airfoil section that extends radially between radially inner and outer fairing platforms. At least one of the fairing platforms includes forward and aft sides, circumferential sides, and a gas path side and an opposed radial side. The radial side includes a plurality of protrusions that have faces that are oriented substantially normal to, respectively, radial, tangential, and axial load transmission directions of the airfoil such that the faces, respectively, primarily bear radial, tangential, and axial load transmissions of the airfoil. |
| FILED | Friday, August 28, 2015 |
| APPL NO | 14/838407 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) Original (OR) Class F01D 9/042 (20130101) F01D 25/28 (20130101) F01D 25/246 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/12 (20130101) F05D 2240/80 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Y02T 50/673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072522 | Nolcheff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nick Nolcheff (Chandler, Arizona); Jong Lee (Tempe, Arizona) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| INVENTOR(S) | Nick Nolcheff (Chandler, Arizona); Jong Lee (Tempe, Arizona) |
| ABSTRACT | A compressor includes a rotor platform; a rotor blade; and a casing having an inner surface surrounding the tip and spaced radially outwardly from the tip to define a gap. A secondary air flow system includes a bleed inlet configured to remove secondary air flow from the primary air flow; an injection opening disposed in the inner surface of the casing upstream of the bleed inlet; an accessory conduit; and a plenum fluidly coupled to the bleed inlet, the injection opening, and the accessory conduit. The bleed inlet and plenum at least partially define a secondary air flow path such that a first portion of the secondary air flow is directed in through the bleed inlet, through the plenum, and out through the injection opening and a second portion of the secondary air flow is directed in through the bleed inlet, through the plenum, and out through the accessory conduit. |
| FILED | Thursday, July 14, 2011 |
| APPL NO | 13/182976 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/04 (20130101) F01D 25/24 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/18 (20130101) Non-positive-displacement Pumps F04D 27/023 (20130101) F04D 27/0215 (20130101) F04D 27/0238 (20130101) F04D 29/545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072991 | Nayfeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by The Secretary of The Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by The Secretary of The Army (Washington, District of Columbia) |
| INVENTOR(S) | Munir H. Nayfeh (Urbana, Illinois); Charles P. Marsh (Urbana, Illinois); Ghassan K. Al-Chaar (Champaign, Illinois) |
| ABSTRACT | A nanoparticle sensor apparatus includes a silicon-based nanoparticle having a centrosymmetric crystalline structure. A lanthanide atom embedded within the silicon-based nanoparticle provides light emission when the sensor apparatus undergoes pressure loading. This sensor apparatus may be encapsulated in a polymer matrix to form a nanoparticle sensor matrix apparatus which may be located on or in a structure. To measure the pressure on such a structure, a UV light source illuminates the sensor apparatus. An optical emission detector detects the intensity of light emitted from the sensor in response, while a processor correlates that intensity to the pressure loading. |
| FILED | Thursday, March 17, 2016 |
| APPL NO | 15/073406 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073035 | Zhuang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaowei Zhuang (Lexington, Massachusetts); Wilfred M. Bates (Gottingen, Germany); Michael J. Rust (Medford, Massachusetts) |
| ABSTRACT | The present invention generally relates to sub-diffraction limit image resolution and other imaging techniques. In one aspect, the invention is directed to determining and/or imaging light from two or more entities separated by a distance less than the diffraction limit of the incident light. For example, the entities may be separated by a distance of less than about 1000 nm, or less than about 300 nm for visible light. In one set of embodiments, the entities may be selectively activatable, i.e., one entity can be activated to produce light, without activating other entities. A first entity may be activated and determined (e.g., by determining light emitted by the entity), then a second entity may be activated and determined. The entities may be immobilized relative to each other and/or to a common entity. The emitted light may be used to determine the positions of the first and second entities, for example, using Gaussian fitting or other mathematical techniques, and in some cases, with sub-diffraction limit resolution. The methods may thus be used, for example, to determine the locations of two or more entities immobilized relative to a common entity, for example, a surface, or a biological entity such as DNA, a protein, a cell, a tissue, etc. The entities may also be determined with respect to time, for example, to determine a time-varying reaction. Other aspects of the invention relate to systems for sub-diffraction limit image resolution, computer programs and techniques for sub-diffraction limit image resolution, methods for promoting sub-diffraction limit image resolution, methods for producing photoswitchable entities, and the like. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/252307 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) C09K 2211/1044 (20130101) C09K 2211/1475 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) G01N 15/1475 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 33/582 (20130101) G01N 2015/0065 (20130101) G01N 2021/6421 (20130101) G01N 2021/6439 (20130101) G01N 2021/6441 (20130101) G01N 2201/12 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/0076 (20130101) G02B 21/367 (20130101) G02B 27/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073087 | Deng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Zhengtao Deng (Cambridge, Massachusetts); Timothy Kuan-Ta Lu (Charlestown, Massachusetts) |
| ABSTRACT | Various aspects and embodiments provided herein are directed to compositions that include at least one nanoparticle linked to a first polypeptide, and a biologically synthesizable polymer linked to at least one second polypeptide that binds covalently to the first polypeptide. Other aspects and embodiments provided herein are directed to methods of producing the foregoing compositions and components therein. |
| FILED | Thursday, January 15, 2015 |
| APPL NO | 14/597575 |
| ART UNIT | 1675 — Printing/Measuring and Testing |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0093 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/521 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073102 | Ratner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Bloodworks (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Bloodworks (Seattle, Washington) |
| INVENTOR(S) | Daniel M. Ratner (Seattle, Washington); Jill M. Johnsen (Seattle, Washington); James T. Kirk (Seattle, Washington); José A. López (Seattle, Washington); Norman D. Brault (Seattle, Washington); Shaoyi Jiang (Redmond, Washington) |
| ABSTRACT | Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/436585 |
| ART UNIT | 1677 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/7703 (20130101) G01N 33/80 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073120 | Hofmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | J.A. WOOLLAM CO., INC. (Lincoln, Nebraska); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | BOARD OF REGENTS FOR THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); J.A. WOOLLAM CO., INC. (Lincoln, Nebraska) |
| INVENTOR(S) | Tino Hofmann (Harrisburg, North Carolina); Mathias M. Schubert (Lincoln, Nebraska); Stefan Schoeche (Lincoln, Nebraska); Philipp Kuehne (Atvidaberg, Sweden); Craig M. Herzinger (Lincoln, Nebraska); John A. Woollam (Lincoln, Nebraska); Gregory K. Pribil (Lincoln, Nebraska); Thomas E. Tiwald (Lincoln, Nebraska); Sean R. Knight (Plattsmouth, Nebraska) |
| ABSTRACT | Optical Hall Effect (OHE) method for evaluating such as free charge carrier effective mass, concentration, mobility and free charge carrier type in a sample utilizing a permanent magnet at room temperature. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 15/732252 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 7/00 (20130101) G01N 21/17 (20130101) G01N 21/211 (20130101) G01N 2021/212 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 19/08 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073177 | Montoya et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Juan C. Montoya (Belmont, Massachusetts); Antonio Sanchez-Rubio (Lexington, Massachusetts); Harold C. Payson (Lexington, Massachusetts); Robert E. Hatch (Boxborough, Massachusetts); Richard Heinrichs (Arlington, Virginia); Dale G. Fried (Dover, Massachusetts) |
| ABSTRACT | A method of imaging a scene includes generating a temporally varying optical intensity pattern from at least one continuous wave (CW) light beam. The method also includes illuminating at least one portion of the scene with the temporally varying optical intensity pattern so as to cause a photon to scatter or reflect off the at least one portion of the scene. The photon reflected or scatted from the at least one portion of the scene is detected using a single-photon detector. Based on the temporally varying optical intensity pattern and a time of flight of the photon detected, a distance between the single-photon detector and the at least one portion of the scene is estimated. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/939213 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/499 (20130101) G01S 7/4815 (20130101) G01S 7/4816 (20130101) G01S 7/4817 (20130101) G01S 7/4863 (20130101) G01S 17/10 (20130101) Original (OR) Class G01S 17/32 (20130101) G01S 17/42 (20130101) G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073191 | Shen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yichen Shen (Cambridge, Massachusetts); Dexin Ye (Hangzhou, China PRC); Ivan Celanovic (Cambridge, Massachusetts); Steven G. Johnson (Arlington, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
| ABSTRACT | A filter to transmit incident radiation at a predetermined incidence angle includes a plurality of photonic crystal structures disposed substantially along a surface normal direction of the filter. The photonic crystal structure includes a multilayer cell that comprises a first layer having a first dielectric permittivity, and a second layer having a second dielectric permittivity different from the first dielectric permittivity. The first layer and the second layer define a Brewster angle substantially equal to the predetermined incidence angle based on the first dielectric permittivity and the second permittivity. Each photonic crystal structure in the plurality of photonic crystal structures defines a respective bandgap, and the respective bandgaps of the plurality of photonic crystal structures, taken together, cover a continuous spectral region of about 50 nm to about 100 mm. |
| FILED | Tuesday, February 24, 2015 |
| APPL NO | 14/630080 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Original (OR) Class G02B 5/20 (20130101) G02B 5/26 (20130101) G02B 5/3066 (20130101) G02B 5/3083 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0131 (20130101) G02F 1/0147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073200 | Gangopadhyay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Shubhra Gangopadhyay (Columbia, Missouri); Venu Korampally (Aurora, Illinois); Sagnik Basuray (Columbia, Missouri); Kunal Bhatnagar (College Station, Texas); Avinash Pathak (Columbia, Missouri); Arnab Ghosh (Columbia, Missouri); Drew Edwin Menke (Berger, Missouri); Joseph Mathai (Columbia, Missouri); Peter Cornish (Columbia, Missouri); Keshab Gangopadhyay (Columbia, Missouri); Aaron Wood (Columbia, Missouri) |
| ABSTRACT | A method of producing a grating structure comprises the steps of forming a stamp from flexible plastic material, the stamp including a negative of a periodic grating pattern on a first surface; forming an ink by applying a polymer film to the stamp, the ink including a first surface and an opposing second surface, wherein the first surface of the ink contacts the first surface of the stamp such that the ink retains a positive of the periodic grating pattern; placing the ink and the stamp on a substrate such that the second surface of the ink contacts an upper surface of the substrate; and removing the stamp from the ink by applying a tensional force to one edge of the stamp. |
| FILED | Friday, November 15, 2013 |
| APPL NO | 14/081353 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/18 (20130101) G02B 5/1814 (20130101) G02B 5/1842 (20130101) Original (OR) Class G02B 5/1852 (20130101) G02B 5/1861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073218 | Setmire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Zachary J. Setmire (Cambridge, Massachusetts); John J. Zayhowski (Cambridge, Massachusetts); Jonathan Wilson (Hampstead, New Hampshire) |
| ABSTRACT | Double-clad optical fibers with polymer outer coatings are used in fiber amplifiers and fiber lasers to guide and amplify light. As the optical power increases, the optical fibers must dissipate more heat. Unfortunately, it is difficult to dissipate heat through a polymer cladding, especially at high altitude, without introducing phase noise in the optical signal. To overcome this problem, the inventors have realized metallized polymer-clad optical fibers with superior heat dissipation characteristics than conventional polymer-clad optical fibers. An example metallized polymer-clad optical fiber includes a thin chrome layer that is vacuum-deposited onto the polymer cladding at low temperature, then electroplated with a thicker copper layer. In operation, the copper layer dissipates heat from within the fiber's core and claddings via a heatsink, enabling the fiber to guide and amplify high-power optical signals at high altitude. |
| FILED | Monday, March 27, 2017 |
| APPL NO | 15/470661 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/036 (20130101) Original (OR) Class G02B 6/443 (20130101) G02B 6/4402 (20130101) G02B 6/4415 (20130101) G02B 6/4488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073775 | Wilerkson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Christopher B. Wilerkson (Portland, Oregon); Ren Wang (Portland, Oregon); Antoine Kaufmann (Hillsboro, Oregon); Anil Vasudevan (Portland, Oregon); Robert G. Blankenship (Tacoma, Washington); Venkata Krishnan (Ashland, Massachusetts); Tsung-Yuan C. Tai (Portland, Oregon) |
| ABSTRACT | An apparatus and method are described for a triggered prefetch operation. For example, one embodiment of a processor comprises: a first core comprising a first cache to store a first set of cache lines; a second core comprising a second cache to store a second set of cache lines; a cache management circuit to maintain coherency between one or more cache lines in the first cache and the second cache, the cache management circuit to allocate a lock on a first cache line to the first cache; a prefetch circuit comprising a prefetch request buffer to store a plurality of prefetch request entries including a first prefetch request entry associated with the first cache line, the prefetch circuit to cause the first cache line to be prefetched to the second cache in response to an invalidate command detected for the first cache line. |
| FILED | Friday, April 01, 2016 |
| APPL NO | 15/089035 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0808 (20130101) Original (OR) Class G06F 12/0811 (20130101) G06F 12/0862 (20130101) G06F 12/0891 (20130101) G06F 2212/602 (20130101) G06F 2212/1016 (20130101) G06F 2212/6022 (20130101) G06F 2212/6028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073809 | Dinan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | James Dinan (Hudson, Massachusetts); Mario Flajslik (Hudson, Massachusetts) |
| ABSTRACT | Technologies for one-side remote memory access communication include multiple computing nodes in communication over a network. A receiver computing node receives a message from a sender node and extracts a segment identifier from the message. The receiver computing node determines, based on the segment identifier, a segment start address associated with a partitioned global address space (PGAS) segment of its local memory. The receiver computing node may index a segment table stored in the local memory or in a host fabric interface. The receiver computing node determines a local destination address within the PGAS segment based on the segment start address and an offset included in the message. The receiver computing node performs a remote memory access operation at the local destination address. The receiver computing node may perform those operations in hardware by the host fabric interface of the receiver computing node. Other embodiments are described and claimed. |
| FILED | Monday, April 27, 2015 |
| APPL NO | 14/696719 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/061 (20130101) G06F 3/067 (20130101) G06F 3/0659 (20130101) G06F 15/17331 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073831 | Beller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Paul J. Chase, Jr. (Fairfax, Virginia); Richard L. Darden (Leesburg, Virginia); Michael Drzewucki (Woodbridge, Virginia); Edward G. Katz (Washington, District of Columbia); Christopher Phipps (Arlington, Virginia); James E. Ramirez (Stephenson, Virginia) |
| ABSTRACT | Large lists of domain-specific terms are classified as a particular kind of linguistic object, e.g., lexical answer type T versus canonical answer E, based on features from a domain-specific corpus which have been found to distinguish between the linguistic objects. The distinguishing features can be identified in the corpus based on sets of the linguistic objects derived from question-and-answer pairs. A classifier can be trained using the distinguishing features, and the classification carried out using that classifier. The distinguishing features can include one or more syntactic features or one or more lexical features. The linguistic objects (the T and E training sets) can be extracted from the question-and-answer pairs automatically via text analysis if manually curated lists are not available. The classified terms can be included in a domain-specific lexicon which facilitates a deep question answering system to yield an answer to a question. |
| FILED | Thursday, March 09, 2017 |
| APPL NO | 15/454778 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 17/21 (20130101) G06F 17/271 (20130101) G06F 17/277 (20130101) Original (OR) Class G06F 17/2715 (20130101) G06F 17/2785 (20130101) G06F 17/30654 (20130101) G06F 17/30684 (20130101) G06F 17/30705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073833 | Beller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); Paul J. Chase, Jr. (Fairfax, Virginia); Richard L. Darden (Leesburg, Virginia); Michael Drzewucki (Woodbridge, Virginia); Edward G. Katz (Washington, District of Columbia); Christopher Phipps (Arlington, Virginia); James E. Ramirez (Stephenson, Virginia) |
| ABSTRACT | Large lists of domain-specific terms are classified as a particular kind of linguistic object, e.g., lexical answer type T versus canonical answer E, based on features from a domain-specific corpus which have been found to distinguish between the linguistic objects. The distinguishing features can be identified in the corpus based on sets of the linguistic objects derived from question-and-answer pairs. A classifier can be trained using the distinguishing features, and the classification carried out using that classifier. The distinguishing features can include one or more syntactic features or one or more lexical features. The linguistic objects (the T and E training sets) can be extracted from the question-and-answer pairs automatically via text analysis if manually curated lists are not available. The classified terms can be included in a domain-specific lexicon which facilitates a deep question answering system to yield an answer to a question. |
| FILED | Friday, June 09, 2017 |
| APPL NO | 15/618910 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 17/21 (20130101) G06F 17/271 (20130101) G06F 17/277 (20130101) Original (OR) Class G06F 17/2715 (20130101) G06F 17/2785 (20130101) G06F 17/30654 (20130101) G06F 17/30684 (20130101) G06F 17/30705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073998 | Tran |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as representd by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nghia X. Tran (San Diego, California) |
| ABSTRACT | A radio frequency identification (RFID) label and an RFID data retrieval device which may be used to aid the visually impaired identify the medicines they take. RFID label includes a memory chip, energy harvesting circuit, and a loop antenna, with the memory chip containing information about the medicine. RFID data retrieval device contains a device controller chip, a wireless transceiver, a switch, a loop antenna, a memory chip, a proximity sensor, an audio digital-to-analog converter (DAC), an audio amplifier, an audio speaker, and also a pair of opposing temporal side members connected to a device controller chip retaining member via hinge. This device controller retaining member contains a recessed for the nose of the visually impaired person. The invention may also include an inductive charging device made up of an inductive charge coil, a power converter, a regulator, a charge controller, and an external power supply, allowing for wireless charging. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/825837 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/04 (20130101) A61F 9/08 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10396 (20130101) Original (OR) Class G06K 19/07758 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/10 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074054 | Adams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Governing Council of the Univ. of Toronto (Toronto, Canada) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Governing Council of the Univ. of Toronto, The (Toronto, Canada) |
| INVENTOR(S) | Ryan P. Adams (Somerville, Massachusetts); Roland Jasper Snoek (Cambridge, Massachusetts); Kevin Swersky (Toronto, Canada); Richard Zemel (Toronto, Canada) |
| ABSTRACT | Techniques for use in connection with performing optimization using an objective function that maps elements in a first domain to values in a range. The techniques include using at least one computer hardware processor to perform: identifying a first point at which to evaluate the objective function at least in part by using an acquisition utility function and a probabilistic model of the objective function, wherein the probabilistic model depends on a non-linear one-to-one mapping of elements in the first domain to elements in a second domain; evaluating the objective function at the identified first point to obtain a corresponding first value of the objective function; and updating the probabilistic model of the objective function using the first value to obtain an updated probabilistic model of the objective function. |
| FILED | Friday, May 30, 2014 |
| APPL NO | 14/291379 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) Computer Systems Based on Specific Computational Models G06N 5/048 (20130101) Original (OR) Class G06N 7/005 (20130101) G06N 99/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074397 | Lacirignola et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Joseph J. Lacirignola (Beverly, Massachusetts); Trina Rae Vian (Westford, Massachusetts); David F. Aubin, Jr. (Pelham, New Hampshire); Thomas F. Quatieri (Newtonville, Massachusetts); Kate D. Fischl (Cambridge, Massachusetts); Paula P. Collins (Arlington, Massachusetts); Christopher J. Smalt (Arlington, Massachusetts); Paul D. Gatewood (Medford, Massachusetts); Nicolas Malyska (Watertown, Massachusetts); David C. Maurer (Stoneham, Massachusetts) |
| ABSTRACT | Loud sounds with fast rise times, like gunfire and explosions, can cause noise-induced hearing loss (NIHL). Unfortunately, current models do not adequately explain how impulsive sounds cause NIHL, which makes it difficult to predict and prevent NIHL on battlefields and other hostile or rugged environments. Fortunately, the impulsive sounds experienced by soldiers and others working in rugged environments can be recorded using a compact, portable system that acquires, digitizes, and stores high-bandwidth audio data. An example of this system can be mounted on a helmet or other article and used to record hours of audio data at a bandwidth of 20 kHz or higher, which is broad enough to capture sounds with rise times less than 50 ms. An analog-to-digital converter (ADC) digitizes these broadband audio signals at rate of 40 kHz or higher to preserve the impulse information. A processor transfers the digitized samples from a buffer to a memory card for later retrieval using an interrupt-driven processing technique. |
| FILED | Wednesday, August 31, 2016 |
| APPL NO | 15/252963 |
| ART UNIT | 2651 — Videophones and Telephonic Communications |
| CURRENT CPC | Electric Digital Data Processing G06F 3/165 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 21/0208 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 20/10 (20130101) Original (OR) Class G11B 20/24 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 3/005 (20130101) H04R 25/75 (20130101) H04R 2430/01 (20130101) H04R 2460/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074505 | Jacobs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Ryan Matthew Jacobs (Madison, Wisconsin); Dane Morgan (Middleton, Wisconsin); John Booske (McFarland, Wisconsin) |
| ABSTRACT | An electron emitter device is provided comprising a cathode comprising a conductive transition metal perovskite oxide comprising mobile conducting electrons exhibiting a conductivity of at least 10−6 Ω−1-cm−1 at room temperature, the transition metal perovskite oxide having a surface from which the mobile electrons are induced to emit upon receiving sufficient energy from an energy source; and an anode electrically coupled to the cathode and positioned to define an interelectrode conductive region between the anode and the cathode, onto which anode the emitted electrons are collected. The transition metal perovskite oxide may have formula Sr1-xBaxVO3. Related methods and devices based on the electron emitter device are also provided. |
| FILED | Thursday, December 08, 2016 |
| APPL NO | 15/372726 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 19/062 (20130101) Original (OR) Class H01J 19/064 (20130101) H01J 23/04 (20130101) H01J 25/42 (20130101) H01J 45/00 (20130101) Amplifiers H03F 3/58 (20130101) H03F 3/189 (20130101) H03F 2200/451 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074544 | Singer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Jonathan Phillip Singer (Cambridge, Massachusetts); Pao Tai Lin (Brighton, Massachusetts); Edwin Lorimer Thomas (Houston, Texas) |
| ABSTRACT | A method for lithographic patterning of thin films. A thin film is deposited on a substrate and the film is exposed to optical energy from a focused laser to induce a thermal gradient in the film by optical absorption. The film is softened through a melting or glass transition process and the thermal gradient induces a directional dewetting down the thermal gradient. The invention permits developer free positive tone lithography by thermal direct write and also metrology of the thin film by the morphology of the resultant features. |
| FILED | Friday, April 18, 2014 |
| APPL NO | 14/256419 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 1/68 (20130101) G03F 7/70383 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/308 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074784 | Schowalter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leo J. Schowalter (Latham, New York); Jianfeng Chen (Ballston Lake, New York); James R. Grandusky (Waterford, New York) |
| ASSIGNEE(S) | CRYSTAL IS, INC. (Green Island, New York) |
| INVENTOR(S) | Leo J. Schowalter (Latham, New York); Jianfeng Chen (Ballston Lake, New York); James R. Grandusky (Waterford, New York) |
| ABSTRACT | In various embodiments, a rigid lens is attached to a light-emitting semiconductor die via a layer of encapsulant having a thickness insufficient to prevent propagation of thermal expansion mismatch-induced strain between the rigid lens and the semiconductor die. |
| FILED | Wednesday, January 14, 2015 |
| APPL NO | 14/596806 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/22 (20130101) H01L 33/54 (20130101) H01L 33/56 (20130101) H01L 33/58 (20130101) Original (OR) Class H01L 33/405 (20130101) H01L 2933/0058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074814 | Goldberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Joshua Goldberger (Columbus, Ohio); Shishi Jiang (Columbus, Ohio); Elisabeth Bianco (Wadsworth, Ohio) |
| ABSTRACT | The present invention provides novel two-dimensional van der Waals materials and stacks of those materials. Also provided are methods of making and using such materials. |
| FILED | Thursday, April 03, 2014 |
| APPL NO | 14/244572 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 6/06 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 17/00 (20130101) C01G 19/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/30 (20130101) C07F 7/2212 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/0665 (20130101) H01L 31/032 (20130101) H01L 31/035209 (20130101) H01L 33/04 (20130101) H01L 33/26 (20130101) H01L 51/42 (20130101) H01L 51/50 (20130101) H01L 51/0077 (20130101) Original (OR) Class H01L 51/0558 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/95 (20130101) Y10S 977/758 (20130101) Y10S 977/788 (20130101) Y10S 977/896 (20130101) Y10S 977/933 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074908 | Buchanan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kristopher Ryan Buchanan (San Diego, California); Carlos Flores-Molina (San Diego, California); Timi Adeyemi (San Diego, California) |
| ABSTRACT | A phased array of electrolytic fluid antennas comprising: a center conduit filled with electrolytic fluid; a current probe having a central hole therein, wherein the center conduit is disposed within the central hole; and a plurality of electrolytic fluid antennas composed of free-standing streams of electrolytic fluid circularly-distributed about the center conduit, wherein each electrolytic fluid antenna is fluidically coupled to the center conduit by a fluid transmission line of a desired length, and wherein each electrolytic fluid antenna is configured to turn on or off in real time to change the characteristics of the phased array. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 15/902346 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/286 (20130101) H01Q 3/26 (20130101) H01Q 21/20 (20130101) H01Q 21/062 (20130101) Original (OR) Class H01Q 21/0087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074955 | Bovington |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oracle International Corporation (Redwood Shores, California) |
| ASSIGNEE(S) | Oracle International Corporation (Redwood Shores, California) |
| INVENTOR(S) | Jock T. Bovington (La Jolla, California) |
| ABSTRACT | The disclosed embodiments improve on the design of existing hybrid ring lasers by enabling a redundancy of one of the least reliable components, the III-V reflective semiconductor optical amplifier (RSOA). This allows a spare RSOA to be used to replace a failed RSOA while using the same ring mirror as the wavelength selective filter, thus reducing link down time, and eliminating the need for additional switching or multiplexing elements which add excess loss and require additional power. The result is a more reliable transmitter enabling greater scale in networking systems. In addition, this facilitates a widely tunable laser with the same outputs by utilizing two gain media comprised of different bandgap active material. Finally, multiple correlated wavelengths can be emitted from this device with two different gain materials using the same ring mirror element as reference. |
| FILED | Wednesday, September 07, 2016 |
| APPL NO | 15/258480 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/083 (20130101) Original (OR) Class H01S 3/10007 (20130101) H01S 5/005 (20130101) H01S 5/142 (20130101) H01S 5/0601 (20130101) H01S 5/0617 (20130101) H01S 5/3013 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074985 | Simburger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Edward J Simburger (Agoura Hills, California) |
| ABSTRACT | A solar and/or wind inverter that uses an ultracapacitor for grid stabilization. The ultracapacitor may be directly tied to, and placed between, a power source and an inverter. The ultracapacitor may supply power to a grid via the inverter during a reduction of power or a loss in power from the grid. |
| FILED | Tuesday, June 21, 2016 |
| APPL NO | 15/188117 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/28 (20130101) Original (OR) Class H02J 3/382 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/563 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/406 (20150401) Y10T 307/516 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075145 | Gu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Qun Gu (Davis, California) |
| ABSTRACT | Methods and apparatuses for measuring a phase noise level in an input signal are disclosed. An input signal can be delayed to generate a delayed version of the input signal. Next, a phase difference can be detected between the input signal and the delayed version of the input signal. A phase noise level in the input signal can then be determined based on the detected phase difference. The measured phase noise level can then be used to suppress phase noise in the input signal. |
| FILED | Thursday, May 25, 2017 |
| APPL NO | 15/605811 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31709 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/075 (20130101) H03H 7/0153 (20130101) H03H 9/02535 (20130101) Original (OR) Class Pulse Technique H03K 5/003 (20130101) H03K 5/14 (20130101) H03K 2005/00045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075233 | Pechner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SA Photonics, Inc. (Los Gatos, California) |
| ASSIGNEE(S) | SA Photonics, Inc. (Los Gatos, California) |
| INVENTOR(S) | David Pechner (San Jose, California) |
| ABSTRACT | Exemplary embodiments described a transmission scheme for use in a bi-directional Free Space Optical (FSO) communication system. Each node locally stores a transmitted data block until and acknowledgement is received that it was properly decoded. In the event that a decode was unsuccessful, the data is retransmitted. The receiving node may then add the received signals to then attempt a decode on a combined signal. The system may also include dynamic controls such that the retransmitted signal may be optimized to improve the probability of a successful decode. |
| FILED | Wednesday, January 28, 2015 |
| APPL NO | 14/608166 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/00 (20130101) Transmission H04B 10/112 (20130101) H04B 10/1123 (20130101) Original (OR) Class H04B 10/1125 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/1845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075245 | Caplan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David O. Caplan (Westford, Massachusetts); Michael R. Watts (Hingham, Massachusetts); Zhan Su (Cambridge, Massachusetts) |
| ABSTRACT | An optical receiver includes a cascade of optical filtering elements, each of which selects spectral components from incoming optical signals at a wavelengths aligned to filter passbands. The selected spectral components may be optically combined to form k pairs of intermediary signals, where k=log2(M). By comparing the k pairs of intermediary signals, k bits of a digital signal representing the incident signal may be generated. The filtering elements may be configured to perform demultiplexing and demodulation simultaneously, increasing functionality and reducing excess losses. The filtering elements may also be tuned so that the optical receiver may be reconfigured to accommodate different combinations of wavelengths and modulation formats, such as wavelength division multiplexed (WDM) on off keying (OOK), M-ary orthogonal formats including frequency shift keying (FSK) and pulse position modulation (PPM), differential phase shift keying, and hybrid combinations—providing rate and format flexibility and WDM scalability. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/148789 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/28 (20130101) Transmission H04B 10/61 (20130101) H04B 10/66 (20130101) H04B 10/671 (20130101) H04B 10/677 (20130101) Original (OR) Class H04B 10/2575 (20130101) Multiplex Communication H04J 14/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075875 | Buyuktosunoglu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Alper Buyuktosunoglu (White Plains, New York); Pradip Bose (Yorktown Heights, New York); Augusto J. Vega (Astoria, New York) |
| ABSTRACT | A computer-implemented method includes determining, by a first base station, that the first base station is overloaded with connections from mobile devices. Responsive to the first base station being overloaded, a status update may be received, by the first base station, from each of a plurality of base stations, where each base station is configured to provide connections to a plurality of mobile devices. Responsive to the first base station being overloaded, a second base station may be selected, by a computer processor of the first base station, from among the plurality of base stations. Responsive to the first base station being overloaded, the second base station may be instructed, by the first base station, to relocate from a first position to a new position closer to the first base station. The plurality of base stations automatically relocate to load-balance connections from the plurality of mobile devices. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/868717 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/16 (20130101) Wireless Communication Networks H04W 28/08 (20130101) Original (OR) Class H04W 28/0226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10070614 | Meksem et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Khalid Meksem (Carbondale, Illinois); Shiming Liu (Carbondale, Illinois); Pramod Kaitheri Kandoth (Columbia, Missouri); Melissa G. Mitchum (Columbia, Missouri) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (Carbondale, Illinois); THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| INVENTOR(S) | Khalid Meksem (Carbondale, Illinois); Shiming Liu (Carbondale, Illinois); Pramod Kaitheri Kandoth (Columbia, Missouri); Melissa G. Mitchum (Columbia, Missouri) |
| ABSTRACT | A transgenic soybean resistant to soybean cyst nematode (SCN), or parts thereof, including an artificial DNA construct encoding a serine hydroxymethyltransferase protein (e.g., GmSHMT). Also provided are GmSHMT alleles containing mutations R130P and Y358N along with research and breeding methods and compositions including such. |
| FILED | Thursday, May 30, 2013 |
| APPL NO | 14/404559 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/04 (20130101) A01H 5/10 (20130101) A01H 6/542 (20180501) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8218 (20130101) C12N 15/8227 (20130101) C12N 15/8285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10070651 | Santra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Swadeshmukul Santra (Oviedo, Florida); Joshua J. Bazata (Winter Springs, Florida) |
| ABSTRACT | The present invention relates to, inter alia, a composition, a nanocomposite material, and a method for preparing the nanocomposite material. The nanocomposite material includes: a dielectric-silver nanocomposite material, the dielectric-silver nanocomposite material including a silver nanoparticle having a silver ion, and a dielectric material encapsulating the silver nanoparticle, where the silver ion chelates with a matrix of the dielectric material, and a surface plasmon band absorption of the dielectric-silver nanocomposite material lies outside a range of a visible region. |
| FILED | Thursday, October 13, 2016 |
| APPL NO | 15/292523 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/28 (20130101) A01N 25/28 (20130101) A01N 59/16 (20130101) Original (OR) Class A01N 59/16 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0018 (20130101) B22F 1/0044 (20130101) B22F 9/24 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/18 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/3054 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10070880 | Bagwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Actuated Medical, Inc. (Bellefonte, Pennsylvania) |
| ASSIGNEE(S) | Actuated Medical, Inc. (Bellefonte, Pennsylvania) |
| INVENTOR(S) | Roger B Bagwell (Bellefonte, Pennsylvania); Brian Matthew Park (Bellefonte, Pennsylvania); Casey A Scruggs (Middleburg, Pennsylvania); Kevin A Snook (State College, Pennsylvania) |
| ABSTRACT | A device for gripping tissue that is inside of a patient for use in delivering therapy is provided. The device may include a first gear that rotates and that engages the tissue. A second gear that also rotates may be included and may likewise engage the tissue. A spacing mechanism may be included in the device that adjusts the spacing between the first and second gears such that the first and second gears are moved closer to one another and moved farther from one another. |
| FILED | Sunday, April 13, 2014 |
| APPL NO | 14/251615 |
| ART UNIT | 3739 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/0014 (20130101) A61B 1/00087 (20130101) A61B 17/29 (20130101) Original (OR) Class A61B 17/22031 (20130101) A61B 18/1492 (20130101) A61B 2017/2943 (20130101) A61B 2017/2947 (20130101) A61B 2018/00208 (20130101) A61B 2018/00291 (20130101) A61B 2018/1405 (20130101) A61B 2218/002 (20130101) A61B 2218/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071248 | Netoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (St. Paul, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Theoden Netoff (Minneapolis, Minnesota); Dan Wilson (Santa Barbara, California); Jeff Moehlis (Santa Barbara, California); Abbey Holt Becker (Minneapolis, Minnesota) |
| ABSTRACT | Systems and methods are provided for determining optimized settings for a closed-loop stimulation system based on analyzing a phase response curve measured from electrophysiological activity, such as electrical nerve activity or electrical muscle activity. The slope of the phase response curve is computed and used to determine a phase window during which phasic burst stimulation should be provided to achieve a desired effect on oscillations in the subject. When the slope of the phase response curve is positive, a phasic burst stimulation applied during the phase window will decrease synchrony of the oscillations. When the slope of the phase response curve is negative, a phasic burst stimulation applied during the phase window will increase synchrony of the oscillations. |
| FILED | Monday, November 07, 2016 |
| APPL NO | 15/344723 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/36067 (20130101) A61N 1/36139 (20130101) Original (OR) Class A61N 1/36178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071359 | Kung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yu-Chun Kung (Los Angeles, California); Pei-Yu E. Chiou (Los Angeles, California); Ting-Hsiang S. Wu (Culver City, California); Yue Chen (Los Angeles, California); Michael A. Teitell (Tarzana, California) |
| ABSTRACT | Methods and devices for the formation and/or merging of droplets in microfluidic systems are provided. In certain embodiments a microfluidic droplet merger component is provided that comprises a central channel comprising a plurality of elements disposed and spaced to create a plurality of lateral passages that drain a carrier fluid out of a fluid stream comprising droplets of a first fluid contained in the carrier fluid; and a deformable lateral membrane valve disposed to control the width of said center channel. |
| FILED | Thursday, March 13, 2014 |
| APPL NO | 14/775611 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00587 (20130101) B01J 2219/00599 (20130101) B01J 2219/00713 (20130101) B01J 2219/00722 (20130101) B01J 2219/00756 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0265 (20130101) B01L 3/502784 (20130101) B01L 7/52 (20130101) B01L 2200/0673 (20130101) B01L 2300/123 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2400/086 (20130101) B01L 2400/0655 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071487 | Rus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniela L. Rus (Weston, Massachusetts); Joseph J. DelPreto (Croton-on-Hudson, New York); Ankur M. Mehta (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods to systematize the development of machines using inexpensive, fast, and convenient fabrication processes are disclosed. In an embodiment, a robot compiler generates a fabrication system, including mechanical, electrical, and software assemblies, that can be used for assembling a robot according to a user design. |
| FILED | Wednesday, May 06, 2015 |
| APPL NO | 14/705493 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 13/00 (20130101) B25J 19/007 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072030 | Toutov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Anton Toutov (Pasadena, California); Kerry Betz (Boulder, Colorado); Brian M. Stoltz (San Marino, California); Wenbo Liu (Pasadena, California); Robert H. Grubbs (South Pasadena, California) |
| ABSTRACT | The present invention is directed to a mild, efficient, and general direct C(sp)-H bond silylation. Various embodiments includes methods, each method comprising or consisting essentially of contacting at least one organic substrate comprising a terminal alkynyl C—H bond, with a mixture of at least one organosilane and an alkali metal hydroxide, alkali metal alkoxide, or alkali metal hydride under conditions sufficient to form a silylated terminal alkynyl moiety. The methods are operable in the presence or substantially absence of transition-metal compounds. The systems associated with these methods are also disclosed. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/375716 |
| ART UNIT | 1671 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0827 (20130101) Original (OR) Class C07F 17/02 (20130101) Steroids C07J 1/0096 (20130101) C07J 7/0005 (20130101) C07J 51/00 (20130101) C07J 75/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072042 | Matyjaszewski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania); Saadyah E. Averick (Pittsburgh, Pennsylvania); Antonina Simakova (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods for conducting controlled grafting-from radical polymerizations from biomolecules under conditions that are biologically compatible are described. The methods provide biomolecule-polymer conjugates with highly controlled structures and narrow polydispersities under aqueous reaction conditions and biological temperatures. Biomolecules, such as proteins and nucleotides can be conjugated to polymers with high levels of control. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 15/378537 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Peptides C07K 1/1077 (20130101) Original (OR) Class C07K 14/765 (20130101) C07K 14/43595 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 283/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072048 | Link et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | A. James Link (Belle Meade, New Jersey); Mikhail O. Maksimov (Princeton, New Jersey) |
| ABSTRACT | Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides. |
| FILED | Thursday, August 29, 2013 |
| APPL NO | 14/424617 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/02 (20130101) Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/33 (20130101) A62D 2101/43 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/286 (20130101) C02F 2101/20 (20130101) Peptides C07K 14/195 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072129 | Loomis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | James Loomis (Melrose, Massachusetts); Balaji Panchapakesan (Northborough, Massachusetts) |
| ABSTRACT | A polymer composite is provided that includes a plurality of heat-absorbing nanomaterials, a plurality of thermally-expanding microspheres, and an elastomeric matrix. In the polymer composite, the heat-absorbing nanomaterials and the thermally-expanding microspheres are dispersed within the elastomeric matrix such that the thermally-expanding microspheres expand and stretch the matrix upon exposure to a thermal stimulus. Methods of forming a thermally-expanding polymer composite are also provided and include the steps of dispersing a plurality of heat-absorbing nanomaterials in an evaporative solvent; combining the dispersion with an amount of an elastomeric material to create a mixture; adding an amount of thermally-expanding microspheres to the mixture; and polymerizing the mixture. Circuits including resistors comprised of the polymer composites are further provided. |
| FILED | Friday, February 07, 2014 |
| APPL NO | 14/766612 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/228 (20130101) Original (OR) Class C08J 2203/22 (20130101) C08J 2333/20 (20130101) C08J 2383/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/01 (20180101) C08K 7/22 (20130101) C08K 7/24 (20130101) C08K 9/10 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Resistors H01C 7/008 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/028 (20130101) H05K 1/167 (20130101) H05K 1/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072178 | Webster et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NDSU RESEARCH FOUNDATION (Fargo, North Dakota) |
| ASSIGNEE(S) | NDSU RESEARCH FOUNDATION (Fargo, North Dakota) |
| INVENTOR(S) | Dean C. Webster (Fargo, North Dakota); James A. Docken, Jr. (Fargo, North Dakota); Satyabrata Samanta (S.Fargo, North Dakota); James A. Bahr (West Fargo, North Dakota) |
| ABSTRACT | The invention relates to a resin having a plurality of cyclic carbonate groups comprising the reaction product of: a) an epoxidized sucrose fatty acid ester resin, and b) carbon dioxide where a) and b) are reacted under conditions sufficient to carbonylate a plurality of the oxirane groups of the epoxidized sucrose fatty acid ester resin, and optionally in the presence of a catalyst or of a solvent. In one embodiment the epoxidized sucrose fatty acid ester resin is epoxidized sucrose soyate. The invention also relates to methods for producing a resin having a plurality of cyclic carbonate groups. In a method of the invention, an epoxidized sucrose fatty acid ester resin is contacted with carbon dioxide under conditions sufficient to carbonylate a plurality of the oxirane groups of the epoxidized sucrose fatty acid ester resin, and optionally in the presence of a catalyst or of a solvent. Other embodiments of the invention relate to curable composition containing a) a resin having a plurality of cyclic carbonate groups; b) an alkyl amine curing agent having two or more reactive amine groups; and c) optionally, a catalyst; and cured compositions and articles. |
| FILED | Wednesday, April 20, 2016 |
| APPL NO | 15/133813 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/027 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/17 (20130101) C08K 5/17 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/3462 (20130101) Compositions of Macromolecular Compounds C08L 69/00 (20130101) C08L 69/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072241 | Lawin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INNOVATIVE SURFACE TECHNOLOGIES, INC. (St. Paul, Minnesota) |
| ASSIGNEE(S) | INNOVATIVE SURFACE TECHNOLOGIES, INC. (St. Paul, Minnesota) |
| INVENTOR(S) | Laurie Lawin (New Brighton, Minnesota); Briana Vogen (Falcon Heights, Minnesota); Daniel Guire (Maplewood, Minnesota); Tahmina Naqvi (Blaine, Minnesota); Leandro Forciniti (North Canton, Ohio) |
| ABSTRACT | Inventive concepts relate generally to the field of cell culture, and more particularly to formation of three-dimensional aggregate(s) of eukaryotic cells. Cell culture vessels including a conical device having an inner surface being hydrophobic; and a frustum defining an open viewing aperture and a narrow end of the conical device are described. Ceil culture vessel arrays, assemblies and kits are described, as well as methods of making and using the devices. |
| FILED | Wednesday, March 12, 2014 |
| APPL NO | 14/774996 |
| ART UNIT | 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/02 (20130101) C12M 23/12 (20130101) C12M 23/22 (20130101) C12M 23/58 (20130101) C12M 25/04 (20130101) C12M 25/06 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) Original (OR) Class C12N 2533/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072295 | Quake et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| INVENTOR(S) | Stephen Quake (Stanford, California); Hei-Mun Christina Fan (Fremont, California) |
| ABSTRACT | The present methods are exemplified by a process in which maternal blood containing fetal DNA is diluted to a nominal value of approximately 0.5 genome equivalent of DNA per reaction sample. Digital analysis is then be used to detect aneuploidy, such as the trisomy that causes Down Syndrome. Since aneuploidies do not present a mutational change in sequence, and are merely a change in the number of chromosomes, it has not been possible to detect them in a fetus without resorting to invasive techniques such as amniocentesis or chorionic villi sampling. Digital amplification allows the detection of aneuploidy using massively parallel amplification and detection methods, examining, e.g., 10,000 genome equivalents. |
| FILED | Tuesday, December 23, 2014 |
| APPL NO | 14/581225 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6851 (20130101) C12Q 1/6851 (20130101) C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2527/125 (20130101) C12Q 2527/137 (20130101) C12Q 2531/113 (20130101) C12Q 2531/113 (20130101) C12Q 2537/143 (20130101) C12Q 2537/157 (20130101) C12Q 2545/114 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072335 | Marquardt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); TRUSTEES OF THE WALTERS ART GALLERY, INC. (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Trustees of the Walters Art Gallery, Inc. (Baltimore, Maryland) |
| INVENTOR(S) | Amy Elizabeth Marquardt (Washington, District of Columbia); Eric Breitung (Washington, District of Columbia); Raymond J. Phaneuf (College Park, Maryland); Glenn Gates (Baltimore, Maryland); Terry Weisser (Baltimore, Maryland) |
| ABSTRACT | A method of coating a metallic object with a substantially invisible protective coating, wherein the coating comprises a first layer, a second layer, and a third layer, each layer comprising a metal oxide or a nitride. The method comprises placing the object in an atomic layer deposition (ALD) reactor; depositing a first layer comprising a metal oxide or a nitride on a surface of the object by ALD; depositing a second layer comprising a metal oxide or a nitride on the first layer by ALD; and depositing a third layer comprising a metal oxide or a nitride on the second layer by ALD, thereby forming the protective coating on the object. |
| FILED | Friday, August 28, 2015 |
| APPL NO | 14/839664 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/402 (20130101) C23C 16/403 (20130101) C23C 16/405 (20130101) C23C 16/407 (20130101) C23C 16/45553 (20130101) C23C 16/45555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072924 | Boyle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | John J. Boyle (St. Louis, Missouri); Guy M. Genin (St. Louis, Missouri); Maiko Kume (St. Louis, Missouri); Robert B. Pless (St. Louis, Missouri); Stavros Thomopoulos (St. Louis, Missouri) |
| ABSTRACT | A computer-implemented method for determining a quantification of the deformation of the sample is implemented using a computer device in communication with a memory. The method includes receiving, by the computer device, a first image of the sample and a second image of the sample. The method also includes registering the first image to the second image using a warping function. The warping function maps a plurality of pixels in the first image to a plurality of pixels in the second image. A first displacement field for the sample is determined based on the warping function, where the first displacement field includes at least a portion of the warping function. A first quantification of the deformation of the sample is determined based at least in part on the displacement field. |
| FILED | Tuesday, March 17, 2015 |
| APPL NO | 15/126852 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/30 (20170101) G06T 2207/10004 (20130101) G06T 2207/30024 (20130101) G06T 2207/30108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073074 | Kumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Ratnesh Kumar (Ames, Iowa); Robert J. Weber (Boone, Iowa); Gunjan Pandey (Ames, Iowa) |
| ABSTRACT | A soil sensor includes a housing, an antenna disposed within the housing, a measurement circuit disposed within the housing and operatively connected to the antenna, the circuit configured to measure impedance of soil at a plurality of different frequencies using the antenna as a sensor electrode, and a wireless interface disposed within the housing and operatively connected to the antenna and configured for wireless communications over the antenna at its communications frequency. |
| FILED | Friday, April 24, 2015 |
| APPL NO | 14/695763 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/028 (20130101) G01N 33/246 (20130101) Original (OR) Class G01N 2033/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073102 | Ratner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Bloodworks (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington); Bloodworks (Seattle, Washington) |
| INVENTOR(S) | Daniel M. Ratner (Seattle, Washington); Jill M. Johnsen (Seattle, Washington); James T. Kirk (Seattle, Washington); José A. López (Seattle, Washington); Norman D. Brault (Seattle, Washington); Shaoyi Jiang (Redmond, Washington) |
| ABSTRACT | Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/436585 |
| ART UNIT | 1677 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/7703 (20130101) G01N 33/80 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073120 | Hofmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | J.A. WOOLLAM CO., INC. (Lincoln, Nebraska); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | BOARD OF REGENTS FOR THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); J.A. WOOLLAM CO., INC. (Lincoln, Nebraska) |
| INVENTOR(S) | Tino Hofmann (Harrisburg, North Carolina); Mathias M. Schubert (Lincoln, Nebraska); Stefan Schoeche (Lincoln, Nebraska); Philipp Kuehne (Atvidaberg, Sweden); Craig M. Herzinger (Lincoln, Nebraska); John A. Woollam (Lincoln, Nebraska); Gregory K. Pribil (Lincoln, Nebraska); Thomas E. Tiwald (Lincoln, Nebraska); Sean R. Knight (Plattsmouth, Nebraska) |
| ABSTRACT | Optical Hall Effect (OHE) method for evaluating such as free charge carrier effective mass, concentration, mobility and free charge carrier type in a sample utilizing a permanent magnet at room temperature. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 15/732252 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 7/00 (20130101) G01N 21/17 (20130101) G01N 21/211 (20130101) G01N 2021/212 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 19/08 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073200 | Gangopadhyay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Shubhra Gangopadhyay (Columbia, Missouri); Venu Korampally (Aurora, Illinois); Sagnik Basuray (Columbia, Missouri); Kunal Bhatnagar (College Station, Texas); Avinash Pathak (Columbia, Missouri); Arnab Ghosh (Columbia, Missouri); Drew Edwin Menke (Berger, Missouri); Joseph Mathai (Columbia, Missouri); Peter Cornish (Columbia, Missouri); Keshab Gangopadhyay (Columbia, Missouri); Aaron Wood (Columbia, Missouri) |
| ABSTRACT | A method of producing a grating structure comprises the steps of forming a stamp from flexible plastic material, the stamp including a negative of a periodic grating pattern on a first surface; forming an ink by applying a polymer film to the stamp, the ink including a first surface and an opposing second surface, wherein the first surface of the ink contacts the first surface of the stamp such that the ink retains a positive of the periodic grating pattern; placing the ink and the stamp on a substrate such that the second surface of the ink contacts an upper surface of the substrate; and removing the stamp from the ink by applying a tensional force to one edge of the stamp. |
| FILED | Friday, November 15, 2013 |
| APPL NO | 14/081353 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/18 (20130101) G02B 5/1814 (20130101) G02B 5/1842 (20130101) Original (OR) Class G02B 5/1852 (20130101) G02B 5/1861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073340 | Rotello et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Vincent M Rotello (Amherst, Massachusetts); Bradley Duncan (Boston, Massachusetts); Li-Sheng Wang (Boston, Massachusetts); Eunhee Jeoung (Boston, Massachusetts); Chandramouleeswaran Subramani (Boston, Massachusetts); Krishnendu Saha (Boston, Massachusetts) |
| ABSTRACT | Various embodiments disclosed relate to protein films and methods of making the same. In various embodiments, the present invention provides a method of making a protein film including placing on a substrate a protein solution, to form a precursor protein film. The protein solution includes one or more proteins. The method includes compressing the precursor protein film to form a protein film. |
| FILED | Friday, October 02, 2015 |
| APPL NO | 14/873540 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/14 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073721 | Rangaswami et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raju Rangaswami (Miami, Florida); Daniel Campello (Miami, Florida); Luis Useche (Miami, Florida); Hector Lopez (Miami, Florida); Ricardo Koller (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Raju Rangaswami (Miami, Florida); Daniel Campello (Miami, Florida); Luis Useche (Miami, Florida); Hector Lopez (Miami, Florida); Ricardo Koller (Miami, Florida) |
| ABSTRACT | Techniques and systems are disclosed for implementing non-blocking writes to eliminate the fetch-before-write requirement by creating an in-memory patch for the updated page and unblocking the calling process. Non-blocking writes eliminate such blocking by buffering the written data elsewhere in memory and unblocking the writing process immediately. Subsequent reads to the updated page locations are also made non-blocking and, in some cases, can be eliminated when the read request can be serviced from in-memory patches. Implementation scenarios can include an operating system (OS) enhancement, revision to an existing OS component (e.g., the OS kernel), special OS component, or enhancement to the software or firmware of the controller software or microcontroller of a storage device or array of storage devices. |
| FILED | Monday, August 17, 2015 |
| APPL NO | 14/827647 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/06 (20130101) G06F 9/545 (20130101) Original (OR) Class G06F 17/30165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073812 | Weldon |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas P. Weldon (Charlotte, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (Charlotte, North Carolina) |
| INVENTOR(S) | Thomas P. Weldon (Charlotte, North Carolina) |
| ABSTRACT | A method to implement circuits and circuit elements having one or more ports may include digitizing, using analog-to-digital converters, continuous-time input signals received from one or more ports of a circuit to form discrete-time input signals. At a digital signal processor, the discrete-time input signals are received and the discrete-time input signals are processed to calculate a desired discrete-time output signals. Using digital-to-analog converters, the calculated desired discrete-time output signal are calculated to form outputs of continuous-time output signals at the one or more ports of the circuit. The continuous-time output signals are output to the same one or more ports that receive the continuous-time input signals; and producing, thereby, a desired relationship between the continuous-time output signals and the continuous-time input signals at the one or more ports. |
| FILED | Friday, October 07, 2016 |
| APPL NO | 15/288104 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 17/10 (20130101) Original (OR) Class Coding; Decoding; Code Conversion in General H03M 1/12 (20130101) H03M 1/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074509 | Pan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Liang Pan (West Lafayette, Indiana); Xianfan Xu (West Lafayette, Indiana) |
| ABSTRACT | A system for generating an electron beam array, comprising a light source, a first substrate having a plurality of plasmonic lenses mounted thereon, the plasmonic lenses configured to received light from the light source and produce an electron emission, and a plurality of electrostatic microlenses configured to focus the electron emissions into a beam for focusing on a wafer substrate. A light source modulator and digital micro mirror may be included which captures light from the light source and projects light beamlets on the plasmonic lenses. |
| FILED | Tuesday, June 07, 2016 |
| APPL NO | 15/176147 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) H01J 37/10 (20130101) Original (OR) Class H01J 37/12 (20130101) H01J 37/3174 (20130101) H01J 2237/202 (20130101) H01J 2237/0492 (20130101) H01J 2237/20221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074814 | Goldberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Joshua Goldberger (Columbus, Ohio); Shishi Jiang (Columbus, Ohio); Elisabeth Bianco (Wadsworth, Ohio) |
| ABSTRACT | The present invention provides novel two-dimensional van der Waals materials and stacks of those materials. Also provided are methods of making and using such materials. |
| FILED | Thursday, April 03, 2014 |
| APPL NO | 14/244572 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 6/06 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 17/00 (20130101) C01G 19/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/30 (20130101) C07F 7/2212 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/0665 (20130101) H01L 31/032 (20130101) H01L 31/035209 (20130101) H01L 33/04 (20130101) H01L 33/26 (20130101) H01L 51/42 (20130101) H01L 51/50 (20130101) H01L 51/0077 (20130101) Original (OR) Class H01L 51/0558 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/95 (20130101) Y10S 977/758 (20130101) Y10S 977/788 (20130101) Y10S 977/896 (20130101) Y10S 977/933 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074819 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Michael Scott Arnold (Middleton, Wisconsin); Padma Gopalan (Madison, Wisconsin); Gerald Joseph Brady (Madison, Wisconsin); Yongho Joo (Madison, Wisconsin); Harold T. Evensen (Verona, Wisconsin) |
| ABSTRACT | High density films of semiconducting single-walled carbon nanotubes having a high degree of nanotube alignment are provided. Also provided are methods of making the films and field effect transistors (FETs) that incorporate the films as conducting channel materials. The single-walled carbon nanotubes are deposited from a thin layer of organic solvent containing solubilized single-walled carbon nanotubes that is spread over the surface of an aqueous medium, inducing evaporative self-assembly upon contacting a solid substrate. |
| FILED | Tuesday, August 01, 2017 |
| APPL NO | 15/665769 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0039 (20130101) H01L 51/0048 (20130101) H01L 51/0049 (20130101) H01L 51/0558 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10071345 | Berchtold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Kathryn A. Berchtold (Los Alamos, New Mexico); Kevin W. Dudeck (Jemez Springs, New Mexico); Rajinder P. Singh (Los Alamos, New Mexico); Ganpat J. Dahe (Pittsburgh, Pennsylvania) |
| ABSTRACT | This disclosure concerns methods for formation of a novel PBI asymmetric hollow fiber membrane and its application for gas separations, gas/vapor separations, gas/liquid separations (i.e., pervaporation), and liquid separations including solute molecule removal from organic solvents and water. |
| FILED | Wednesday, June 22, 2016 |
| APPL NO | 15/190011 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 61/36 (20130101) B01D 61/362 (20130101) B01D 63/022 (20130101) B01D 69/087 (20130101) Original (OR) Class B01D 71/62 (20130101) B01D 2256/16 (20130101) B01D 2257/504 (20130101) B01D 2323/12 (20130101) B01D 2323/26 (20130101) B01D 2323/30 (20130101) B01D 2325/20 (20130101) B01D 2325/022 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/448 (20130101) C02F 2101/30 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071350 | Lewis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jennifer A. Lewis (Cambridge, Massachusetts); Thomas J. Ober (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure relates to a device for three-dimensional ink deposition from an impeller-driven active mixing microfluidic printing nozzle. The device is configured to receive a material property associated with the plurality of fluids and receive a structure property of the printing nozzle. The device then determines a threshold relation between a rotating speed Ω of an impeller in the nozzle and a volumetric flow rate Q of fluids that flow through the nozzle based on the material property of the plurality of fluids, the structure property of the printing nozzle. Based on the threshold relation, the device then determines an actual volumetric flow rate of the fluids and actual rotation speed of the impeller. |
| FILED | Thursday, April 07, 2016 |
| APPL NO | 15/564396 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0861 (20130101) B01F 3/0865 (20130101) B01F 3/1221 (20130101) B01F 7/06 (20130101) B01F 7/248 (20130101) B01F 13/0064 (20130101) B01F 15/00253 (20130101) B01F 15/00389 (20130101) Original (OR) Class Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/30 (20130101) Preparing Clay; Producing Mixtures Containing Clay or Cementitious Material, e.g Plaster B28C 5/026 (20130101) B28C 5/1292 (20130101) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/175 (20130101) B41J 2/211 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072173 | Clear et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota) |
| ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
| INVENTOR(S) | Susannah C. Clear (Hastings, Minnesota); Raghunath Padiyath (Woodbury, Minnesota); Garry W. Lachmansingh (Plymouth, Minnesota); Mark A. Strobel (Maplewood, Minnesota); Sonja S. Mackey (St. Paul, Minnesota); Naiyong Jing (Woodbury, Minnesota) |
| ABSTRACT | A coating composition is disclosed. The coating composition includes a poly(methyl methacrylate) polymer or copolymer having a weight average molecular weight of at least 50,000 grams per mole; monomer comprising at least one of an alkylene diacrylate, alkylene dimethacrylate, cycloalkylene diacrylate, or cycloalkylenedimethacrylate, wherein the at least one of an alkylene diacrylate, alkylene dimethacrylate, cycloalkylene diacrylate, or cycloalkylenedimethacrylate provides at least 80 percent by weight of the monomer; and a stabilizer against ultraviolet light. An article including a coating on a surface of a substrate and a method of making the article are also disclosed. The coating on the surface of the substrate is obtained by curing the disclosed coating composition. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 14/387072 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 5/3435 (20130101) C08K 5/3492 (20130101) Compositions of Macromolecular Compounds C08L 2312/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/06 (20130101) C09D 7/48 (20180101) C09D 133/12 (20130101) Original (OR) Class C09D 133/14 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/259 (20150115) Y10T 428/3154 (20150401) Y10T 428/31507 (20150401) Y10T 428/31797 (20150401) Y10T 428/31913 (20150401) Y10T 428/31938 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072224 | Klausner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | James F. Klausner (Gainesville, Florida); Joerg Petrasch (Dornbin, Austria); Nicholas AuYeung (Gainesville, Florida); Ayyoub Mehdizadeh Momen (Gainesville, Florida); Rishi Mishra (Gainesville, Florida); Jinchao Lu (Gainesville, Florida); David Worthington Hahn (Gainesville, Florida); Nikhil Sehgal (Navi Mumbai, India); Renwei Mei (Gainesville, Florida); Benjamin Greek (Gainesville, Florida) |
| ABSTRACT | Disclosed herein is a solar reactor comprising a reactor member; an aperture for receiving solar radiation, the aperture being disposed in a plane on a wall of the reactor member, where the plane is oriented at any angle other than parallel relative to the centerline of the reactor member; a plurality of absorber tubes, wherein the absorber tubes are oriented such that their respective centerlines are at an angle other than 90° relative to the centerline of the reactor member; and wherein the aperture has a hydraulic diameter that is from 0.2 to 4 times a hydraulic diameter of at least one absorber tube in the plurality of absorber tubes; and a reactive material, the reactive material being disposed in the plurality of absorber tubes. |
| FILED | Tuesday, June 10, 2014 |
| APPL NO | 14/896993 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/065 (20130101) B01J 8/067 (20130101) B01J 8/0257 (20130101) B01J 8/0278 (20130101) B01J 19/02 (20130101) B01J 19/127 (20130101) B01J 19/2425 (20130101) B01J 2208/00398 (20130101) B01J 2208/00451 (20130101) B01J 2219/0218 (20130101) B01J 2219/0263 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/46 (20130101) C10J 3/48 (20130101) Original (OR) Class C10J 3/721 (20130101) C10J 2300/0969 (20130101) C10J 2300/0976 (20130101) C10J 2300/1292 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 2/07 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072280 | McBrayer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Brett McBrayer (Davis, California); Tarana Shaghasi (Davis, California); Elena Vlasenko (Davis, California) |
| ABSTRACT | The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof. |
| FILED | Wednesday, February 01, 2017 |
| APPL NO | 15/422245 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/22 (20130101) C12N 9/248 (20130101) C12N 9/2402 (20130101) C12N 9/2437 (20130101) C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/12 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 21/02 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01 (20130101) C12Y 302/01004 (20130101) C12Y 302/01008 (20130101) C12Y 302/01021 (20130101) C12Y 302/01037 (20130101) C12Y 302/01091 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072319 | Braydich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GDC Industries, LLC (Dayton, Ohio) |
| ASSIGNEE(S) | GDC Industries, LLC (Dayton, Ohio) |
| INVENTOR(S) | Michael Dennis Braydich (Beavercreek, Ohio); Harry Couch (Beavercreek, Ohio); Louis A. Luedtke (Centerville, Ohio) |
| ABSTRACT | There are provided methods and systems for creating multi-phase covetics. For example, there is provided a process for making a composite material. The process includes forming a multi-phase covetic. The forming includes heating a melt including a metal in a molten state and a carbon source to a first temperature threshold to form metal-carbon bonds. The forming further includes subsequently heating the melt to a second temperature threshold, the second temperature threshold being greater than the first temperature threshold. The second temperature threshold is a temperature at or above which ordered multi-phase covetics form in the melt. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 15/484595 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/026 (20130101) Original (OR) Class C22C 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072334 | Tong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KLA-Tencor Corporation (Milpitas, California); UChicago Argonne LLC (Chicago, Illinois) |
| ASSIGNEE(S) | KLA-Tencor Corporation (Milpitas, California); UChicago Argonne LLC (Chicago, Illinois) |
| INVENTOR(S) | William M. Tong (San Francisco, California); Alan D. Brodie (Palo Alto, California); Jeffrey Elam (Elmhurst, Illinois); Anil Mane (Naperville, Illinois) |
| ABSTRACT | A digital pattern generator has a MEMS substrate with a plurality of doping layers and a plurality of insulating layers between respective doping layers. A plurality of lenslets are formed as holes through the substrate. A charge drain coating is applied to the inner surfaces of the lenslets. The charge drain coating drains electrons that come into contact with the charge drain coating so that the performance of the digital pattern generator will not be hindered by electron charge build-up. The charge drain coating includes a doping material that coalesces into clusters that are embedded within a high dielectric insulating material. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/786358 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0008 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/32 (20130101) C23C 16/34 (20130101) C23C 16/40 (20130101) C23C 16/402 (20130101) C23C 16/403 (20130101) C23C 16/405 (20130101) C23C 16/45529 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/12 (20130101) H01J 37/026 (20130101) H01J 37/3174 (20130101) H01J 2237/1205 (20130101) H01J 2237/31794 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072345 | Tao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meng Tao (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Meng Tao (Scottsdale, Arizona) |
| ABSTRACT | The present disclosure provides methods and systems for electrorefining high-purity materials, for example, silicon. An exemplary system includes at least one cathode, an anode, and a reference electrode. At least one controller, for example a potentiostat, is used to control the potential difference between a reference electrode and a cathode or anode. The system can be operated in a single phase or multiple phase operation to produce high-purity materials, such as solar-grade silicon. |
| FILED | Monday, November 24, 2014 |
| APPL NO | 14/551747 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/037 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/006 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/02 (20130101) Original (OR) Class C25C 7/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/182 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/546 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072356 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Yanfeng Jiang (Minneapolis, Minnesota); Md Aminul Mehedi (Minneapolis, Minnesota) |
| ABSTRACT | A magnetic material may include α″-Fe16(NxZ1-x)2 or a mixture of α″-Fe16N2 and α″-Fe16Z2, where Z includes at least one of C, B, or O, and x is a number greater than zero and less than one. In some examples, the magnetic material including α″-Fe16(NxZ1-x)2 or a mixture of α″-Fe16N2 and α″-Fe16Z2 may include a relatively high magnetic saturation, such as greater than about 219 emu/gram, greater than about 242 emu/gram, or greater than about 250 emu/gram. In addition, in some examples, the magnetic material including α″-Fe16(NxZ1-x)2 or a mixture of α″-Fe16N2 and α″-Fe16Z2 may include a relatively low coercivity. Techniques for forming the magnetic material are also described. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 14/820284 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/04 (20130101) B22F 2009/041 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/0622 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/26 (20130101) C21D 6/00 (20130101) Alloys C22C 1/1031 (20130101) C22C 1/1084 (20130101) C22C 33/0292 (20130101) C22C 38/001 (20130101) C22C 38/002 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/26 (20130101) C23C 14/48 (20130101) C23C 14/5806 (20130101) C23C 16/36 (20130101) C23C 16/56 (20130101) C23C 16/4488 (20130101) C23C 28/04 (20130101) C23C 28/42 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 19/00 (20130101) C30B 23/00 (20130101) C30B 25/00 (20130101) C30B 29/38 (20130101) Original (OR) Class C30B 33/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/08 (20130101) H01F 1/065 (20130101) H01F 10/147 (20130101) H01F 41/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072638 | McKay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ian McKay (Seattle, Washington); Evelyn Wang (Cambridge, Massachusetts) |
| ABSTRACT | A device for thermal energy harvesting can use pulsed heat. |
| FILED | Thursday, January 09, 2014 |
| APPL NO | 14/151224 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 5/025 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/04 (20130101) Original (OR) Class F03G 7/06 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072879 | El-Kady et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Ihab Fathy El-Kady (Albuquerque, New Mexico); Charles M Reinke (Albuquerque, New Mexico); Roy H. Olsson (Albuquerque, New Mexico); Brian S. Swartzentruber (Albuquerque, New Mexico); Collin J. Delker (Albuquerque, New Mexico); Jinkyoung Yoo (Los Alamos, New Mexico) |
| ABSTRACT | Methods and apparatus for removing heat from an object for the purpose of cooling or for the purpose of generating electrical power are disclosed. In an embodiment, at least two field-effect transistors (FETs) are operated under inversion. While the FETs are being operated, heat is conducted from the object through body portions of said FETs to an element configured for dissipating the conducted heat. |
| FILED | Monday, April 20, 2015 |
| APPL NO | 14/691441 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/02 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/38 (20130101) H01L 35/22 (20130101) H01L 35/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073191 | Shen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yichen Shen (Cambridge, Massachusetts); Dexin Ye (Hangzhou, China PRC); Ivan Celanovic (Cambridge, Massachusetts); Steven G. Johnson (Arlington, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
| ABSTRACT | A filter to transmit incident radiation at a predetermined incidence angle includes a plurality of photonic crystal structures disposed substantially along a surface normal direction of the filter. The photonic crystal structure includes a multilayer cell that comprises a first layer having a first dielectric permittivity, and a second layer having a second dielectric permittivity different from the first dielectric permittivity. The first layer and the second layer define a Brewster angle substantially equal to the predetermined incidence angle based on the first dielectric permittivity and the second permittivity. Each photonic crystal structure in the plurality of photonic crystal structures defines a respective bandgap, and the respective bandgaps of the plurality of photonic crystal structures, taken together, cover a continuous spectral region of about 50 nm to about 100 mm. |
| FILED | Tuesday, February 24, 2015 |
| APPL NO | 14/630080 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Original (OR) Class G02B 5/20 (20130101) G02B 5/26 (20130101) G02B 5/3066 (20130101) G02B 5/3083 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0131 (20130101) G02F 1/0147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073739 | Andrade Costa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Carlos H. Andrade Costa (White Plains, New York); Chen-Yong Cher (Port Chester, New York); Yoonho Park (Chappaqua, New York); Bryan S. Rosenburg (Cortlandt Manor, New York); Kyung D. Ryu (New City, New York) |
| ABSTRACT | A method for selective duplication of subtasks in a high-performance computing system includes: monitoring a health status of one or more nodes in a high-performance computing system, where one or more subtasks of a parallel task execute on the one or more nodes; identifying one or more nodes as having a likelihood of failure which exceeds a first prescribed threshold; selectively duplicating the one or more subtasks that execute on the one or more nodes having a likelihood of failure which exceeds the first prescribed threshold; and notifying a messaging library that one or more subtasks were duplicated. |
| FILED | Wednesday, December 02, 2015 |
| APPL NO | 14/957584 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/008 (20130101) G06F 11/203 (20130101) G06F 11/302 (20130101) G06F 11/0754 (20130101) G06F 11/1415 (20130101) Original (OR) Class G06F 11/1482 (20130101) G06F 11/1492 (20130101) G06F 11/2023 (20130101) G06F 11/2048 (20130101) G06F 11/3409 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073764 | Sundermier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Amy Sundermier (Albuquerque, New Mexico); Bettina K. Arpin (Albuquerque, New Mexico); David Karmol (Seattle, Washington); Lawrence P. Ray (Albuquerque, New Mexico); Kenneth Michael Munoz (Rio Rancho, New Mexico); William Lawry (Albuquerque, New Mexico); Jamie L. Coram (Albuquerque, New Mexico); Thomas Anthony Artale (Erie, Colorado); Patrick DeMoss (Albuquerque, New Mexico); Lucas Leighton Nunno (Albuquerque, New Mexico); Aaron Easter (Blue Springs, Missouri) |
| ABSTRACT | Various technologies pertaining to computer-executable instruction sequence forensics are described herein. In a general embodiment, an application development framework supports a function library that includes a plurality of recording functions. Calls to these functions are inserted into source code or bytecode of the computer-executable instruction sequence. The source code is then compiled, resulting in formation of instrumented machine code of the computer-executable instruction sequence. Alternately, the runtime environment interprets instrumented bytecode for the instruction sequence. A processor executes the machine code, and the called functions cause the processor to generate forensic data pertaining to portions of the computer-executable instruction sequence that correspond to locations in the source code where the calls were inserted. An execution instance of the computer-executable instruction sequence is visualized based upon the forensic data. |
| FILED | Wednesday, July 29, 2015 |
| APPL NO | 14/812842 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/70 (20130101) G06F 8/75 (20130101) G06F 11/3688 (20130101) G06F 11/3692 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074014 | Teuton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jeremy R. Teuton (Pasco, Washington); Richard L. Griswold (West Richland, Washington) |
| ABSTRACT | Innovations in the identification or classification of features in a data set are described, such as a data set representing measurements taken by a scientific instrument. For example, a task-specific processing component, such as a video encoder, is used to generate task-specific metadata. When the data set includes video frames, metadata can include information regarding motion of image elements between frames, or other differences between frames. A feature of the data set, such as an event, can be identified or classified based on the metadata. For example, an event can be identified when metadata for one or more elements of the data set exceed one or more threshold values. When the feature is identified or classified, an output, such as a display or notification, can be generated. Although the metadata may be useable to generate a task-specific output, such as compressed video data, the identifying or classifying is not used solely in production of, or the creation of an association with, the task-specific output. |
| FILED | Wednesday, April 06, 2016 |
| APPL NO | 15/092548 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30038 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/00765 (20130101) Original (OR) Class G06K 2009/00738 (20130101) G06K 2209/27 (20130101) G06K 2209/403 (20130101) Pictorial Communication, e.g Television H04N 19/25 (20141101) H04N 19/46 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074522 | Stevens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | James E. Stevens (Albuquerque, New Mexico); Patrick R. Mickel (Albuquerque, New Mexico); Andrew Lohn (Santa Monica, California); Matthew Marinella (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to systems and methods for preparing reactively sputtered films. The films are generally thin transition metal oxide (TMO) films having an optimum stoichiometry for any useful device (e.g., a sub-stoichiometric thin film for a memristor device). Described herein are systems, methods, and calibrations processes that employ rapid control of partial pressures to obtain the desired film. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 14/671284 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/3492 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32449 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074815 | Forrest et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Jaesang Lee (Seoul, South Korea); Mark E. Thompson (Anaheim Hills, California) |
| ABSTRACT | An organic light emitting device is disclosed in which the emissive dopant material in its organic emissive layer is an organic phosphorescent emissive material and a neat film of the organic phosphorescent emissive material is disposed between the organic emissive layer and the anode as an electron blocking layer. |
| FILED | Thursday, March 31, 2016 |
| APPL NO | 15/086795 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/025 (20130101) C09K 2211/185 (20130101) C09K 2211/1007 (20130101) C09K 2211/1011 (20130101) C09K 2211/1014 (20130101) C09K 2211/1044 (20130101) C09K 2211/1059 (20130101) C09K 2211/1088 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0058 (20130101) H01L 51/0067 (20130101) H01L 51/0072 (20130101) H01L 51/0085 (20130101) Original (OR) Class H01L 51/5016 (20130101) H01L 51/5096 (20130101) H01L 2251/5346 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/14 (20130101) H05B 33/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074996 | Stefanopoulou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anna G. Stefanopoulou (Ann Arbor, Michigan); Shankar Narayan Mohan (Ann Arbor, Michigan); Youngki Kim (Ann Arbor, Michigan); Jason B. Siegel (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Anna G. Stefanopoulou (Ann Arbor, Michigan); Shankar Narayan Mohan (Ann Arbor, Michigan); Youngki Kim (Ann Arbor, Michigan); Jason B. Siegel (Ann Arbor, Michigan) |
| ABSTRACT | There is disclosed an electrical device including a battery pack, a pressure sensor for measuring a volume change of the battery pack, a voltage sensor in electrical communication with a positive terminal and a negative terminal of the battery pack, a temperature sensor positioned in a cell of the battery pack, and a battery management system. The battery management system includes a controller in electrical communication with the pressure sensor, the voltage sensor, and the temperature sensor, the controller being configured to execute a program stored in the controller to determine a state of charge percentage of the battery pack based on a pressure reading from the pressure sensor, a terminal voltage reading from the voltage sensor, and a temperature reading from the temperature sensor. |
| FILED | Friday, August 28, 2015 |
| APPL NO | 14/839096 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3634 (20130101) G01R 31/3655 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0021 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 10/7055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075104 | Sheldon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Matthew Sheldon (Los Angeles, California); Harry A. Atwater (S. Pasadena, California) |
| ABSTRACT | A plasmoelectric device for conversion of optical power to direct current (DC) electrical power includes a first plasmonic nanostructure having a first resonance value and a second plasmonic nanostructure having a second resonance value. The first and second plasmonic nanostructures are electrically coupled and the first plasmonic nanostructure is configured to receive irradiation at a first irradiation value and the second plasmonic nanostructure is configured to receive irradiation at a second irradiation value, to induce charge transfer between the first and second plasmonic nanostructures. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 13/679995 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Electric Machines Not Otherwise Provided for H02N 6/00 (20130101) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 99/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075383 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Weiwei Jiang (New York, New York); Greg Sadowski (Cambridge, Massachusetts) |
| ABSTRACT | Systems, apparatuses, and methods for implementing an asynchronous router with virtual channel (VC) control. The asynchronous router may support multiple VCs for connections to other routers. The asynchronous router may include an interface unit on each switch boundary, with each interface unit including a data merge unit. The data merge unit may include a full detector unit for each VC, with the full detector unit counting the number of flits sent out on a respective VC and counting the number of credits released by the successor router. Whenever the successor router has no credits available, the full detector unit will assert the full signal to prevent any input requests from requesting to transmit over that particular VC. When the full signal is asserted, a timer unit may be activated to repeatedly check if any credits have been released in the successor router. |
| FILED | Wednesday, March 30, 2016 |
| APPL NO | 15/085783 |
| ART UNIT | 2471 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/527 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075657 | Fahim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| INVENTOR(S) | Farah Fahim (Glen Ellyn, Illinois); Grzegorz W. Deptuch (Forest Park, Illinois); Pawel Grybos (Rzaska, Poland); Robert Szczygiel (Cracow, Poland); Piotr Maj (Cracow, Poland); Piotr Kmon (Niepolomice, Poland); David Peter Siddons (Cutchogue, New York); Joseph Mead (Manorville, New York); Abdul Khader Rumaiz (Nesconset, New York); Robert Kent Bradford (Aurora, Illinois); John Thomas Weizeorick, III (Naperville, Illinois) |
| ABSTRACT | A detecting apparatus includes a multi-tier 3D integrated ASIC comprising one or more analog tiers and one or more digital tiers, and a sensor bonded to the multi-tier 3D integrated ASIC. The detecting apparatus includes an electrical substrate and a group of FPGAs or custom data management ASICs. The detecting apparatus also includes a thermal management system, a power distribution system and one or more connectors to transfer data to a data acquisition system configured for radiation spectroscopy or imaging with zero suppressed or full frame readout. |
| FILED | Wednesday, July 20, 2016 |
| APPL NO | 15/214933 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2055 (20130101) Pictorial Communication, e.g Television H04N 5/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10071801 | North et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | David D. North (Williamsburg, Virginia); Mark J. Aull (Cincinatti, Ohio); William J. Fredericks (Williamsburg, Virginia); Mark D. Moore (Williamsburg, Virginia); Paul M. Rothhaar (Newport News, Virginia); William T. Hodges (Yorktown, Virginia); Zachary R. Johns (Virginia Beach, Virginia) |
| ABSTRACT | Systems, methods, and devices provide a vehicle, such as an aircraft, with rotors configured to function as a tri-copter for vertical takeoff and landing (“VTOL”) and a fixed-wing vehicle for forward flight. One rotor may be mounted at a front of the vehicle fuselage on a hinged structure controlled by an actuator to tilt from horizontal to vertical positions. Two additional rotors may be mounted on the horizontal surface of the vehicle tail structure with rotor axes oriented vertically to the fuselage. For forward flight of the vehicle, the front rotor may be rotated down such that the front rotor axis may be oriented horizontally along the fuselage and the front rotor may act as a propeller. For vertical flight, the front rotor may be rotated up such that the front rotor axis may be oriented vertically to the fuselage, while the tail rotors may be activated. |
| FILED | Thursday, March 24, 2016 |
| APPL NO | 15/080167 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 5/02 (20130101) B64C 25/52 (20130101) B64C 29/0025 (20130101) B64C 29/0033 (20130101) Original (OR) Class B64C 39/024 (20130101) B64C 2201/042 (20130101) B64C 2201/044 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) B64D 2027/026 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/44 (20130101) Y02T 50/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071823 | Turse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Composite Technology Development, Inc. (Lafayette, Colorado) |
| ASSIGNEE(S) | COMPOSITE TECHNOLOGY DEPARTMENT, INC. (Lafayette, Colorado) |
| INVENTOR(S) | Dana Turse (Broomfield, Colorado); Robert Taylor (Superior, Colorado); Larry G. Adams (Thornton, Colorado); Doug Richardson (Westminster, Colorado) |
| ABSTRACT | An asymmetric mast is disclosed that can be used for solar arrays. The asymmetric mast can have an asymmetry out of the plane of the solar blanket. The mast may include two or more booms that comprise slit tube longerons. In some embodiments, a single mast can be used with one or two solar blankets. |
| FILED | Wednesday, November 26, 2014 |
| APPL NO | 14/555265 |
| ART UNIT | 3638 — Static Structures, Supports and Furniture |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/44 (20130101) B64G 1/222 (20130101) Original (OR) Class B64G 1/443 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071824 | Reth |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan D Reth (Grasonville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan D Reth (Grasonville, Maryland) |
| ABSTRACT | A method and apparatus for estimating gyro scale factor during normal spacecraft operations, using small attitude motions that are compliant with mission pointing accuracy and stability requirements and a signal processing method that specifically detects the intentionally induced motions. This process increases operational availability by avoiding the need to take the spacecraft offline for large calibration maneuvers. |
| FILED | Friday, February 08, 2013 |
| APPL NO | 13/762649 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/288 (20130101) Original (OR) Class Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 25/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072239 | Berberoglu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia); The Board of Regents of the University of Texas (Austin, Texas) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of the NASA (Washington, District of Columbia) |
| INVENTOR(S) | Halil Berberoglu (Austin, Texas); Thomas E. Murphy (Austin, Texas); Leslie E. Bebout (Santa Cruz, California); Erich D. Fleming (Redwood City, California) |
| ABSTRACT | A life support system for providing a growth medium for at least one photosynthetic micro-organism and for converting CO2 to O2, with reduced water use that is as low as about 4 percent of the corresponding amount of water normally required for conventional micro-organism growth. The system includes a liquid transport capillary channel, a mixed culture photosynthetic biofilm and a liquid transport substrate that is positioned between and contiguous to the capillary channel and the biofilm, where the liquid transport rate is adjustable by adjustment of the local humidity. Approximately uniform radiation is received by the biofilm and contributes to microorganism growth. |
| FILED | Thursday, June 27, 2013 |
| APPL NO | 13/929646 |
| ART UNIT | 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072612 | Bostwick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vector Launch Inc. (Tucson, Arizona) |
| ASSIGNEE(S) | Vector Launch Inc. (Tucson, Arizona) |
| INVENTOR(S) | Christopher Bostwick (Long Beach, California); John Garvey (Long Beach, California); Christopher Anderson (San Marcos, California); Eric Besnard (Long Beach, California) |
| ABSTRACT | Provided herein are various improvements to rocket engine components and rocket engine operational techniques. In one example, a rocket engine propellant injection apparatus is provided that includes a manifold formed into a single body by an additive manufacturing process and comprising a fuel cavity and an oxidizer cavity. The manifold also includes one or more propellant feed stubs, the one or more propellant feed stubs protruding from the manifold and formed into the single body of the manifold by the additive manufacturing process, with at least a first stub configured to carry fuel to the fuel cavity and at least a second stub configured to carry oxidizer to the oxidizer cavity. The manifold also includes a plurality of injection features formed by apertures in a face of the manifold, ones of the plurality of injection features configured to inject the fuel and the oxidizer for combustion. |
| FILED | Tuesday, October 04, 2016 |
| APPL NO | 15/285324 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1055 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Jet-propulsion Plants F02K 9/52 (20130101) Original (OR) Class F02K 9/566 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072840 | Haskin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Henry H. Haskin (Newport News, Virginia); Peter Vasquez (Gloucester, Virginia) |
| ABSTRACT | A flame holder system includes a modified torch body and a ceramic flame holder. Catch pin(s) are coupled to and extend radially out from the torch body. The ceramic flame holder has groove(s) formed in its inner wall that correspond in number and positioning to the catch pin(s). Each groove starts at one end of the flame holder and is can be shaped to define at least two 90° elbows. Each groove is sized to receive one catch pin therein when the flame holder is fitted over the end of the torch body. The flame holder is then manipulated until the catch pin(s) butt up against the end of the groove(s). |
| FILED | Monday, September 09, 2013 |
| APPL NO | 14/021325 |
| ART UNIT | 3749 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Burners F23D 14/52 (20130101) F23D 14/58 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 403/587 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073023 | Bencic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy J. Bencic (Highland Heights, Ohio); David P. Rohler (Shaker Heights, Ohio); Amy F. Fagan (Fairview Park, Ohio); Steven H. Izen (Shaker Heights, Ohio); Arjun K. Maniyedath (Beachwood, Ohio) |
| ASSIGNEE(S) | Plexar Associates, Inc. (Shaker Heights, Ohio) |
| INVENTOR(S) | Timothy J. Bencic (Highland Heights, Ohio); David P. Rohler (Shaker Heights, Ohio); Amy F. Fagan (Fairview Park, Ohio); Steven H. Izen (Shaker Heights, Ohio); Arjun K. Maniyedath (Beachwood, Ohio) |
| ABSTRACT | A tomography duct for wind tunnels includes a plurality of light sources and sensors displaced around a support structure. The light sources are cycled and sensor measurements are made from sensors opposite the light sources. Tomographic algorithms are used to determine an extinction map from the sensor measurements. The extinction map provides details about particles in a cross-section of the air flow through the tomography duct. |
| FILED | Wednesday, June 01, 2016 |
| APPL NO | 15/170715 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) Original (OR) Class G01N 33/0009 (20130101) G01N 33/0031 (20130101) G01N 33/0036 (20130101) G01N 2015/0026 (20130101) G01N 2015/0046 (20130101) G01N 2015/0693 (20130101) G01N 2033/1873 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073115 | Tokars et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Roger P. Tokars (LaGrange, Ohio); John D. Lekki (Elyria, Ohio) |
| ABSTRACT | A self-diagnostic accelerometer (SDA) field programmable gate array (FPGA) may be capable of real time or near-real time diagnostic processing to determine potential accelerometer issues during flight or other mission critical operational situations. The SDA FPGA may determine accelerometer structural health and an attachment condition using an electronics system that is smaller, more energy efficient, and more cost effective than previous diagnostic tools. Advantages of the system may include diagnosing sensors automatically, immediately, actively (i.e., confirming the fault), and consistently, without the influence of a human operator. Customizable SDA algorithms may be adjusted to the specific needs of the sensor/environment. |
| FILED | Monday, April 18, 2016 |
| APPL NO | 15/131089 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/09 (20130101) G01P 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074282 | Wilber |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | George Wilber (Bellevue, Washington) |
| ABSTRACT | A system for providing flight interval management (FIM) instructions to a pilot of an aircraft includes a module coupled to a display device and configured to communicate with a FIM avionics device. The module generates a first output when input data from the FIM avionics device indicates that the aircraft is within 30 nautical miles of another aircraft, and a second input when a lack of valid input data indicates that the module has lost connectivity to the FIM avionics device. The first input is to the display device to present at least an indication of a paired mode of the module with the FIM avionics device, and a commanded speed reported by the FIM avionics device. The second output is to remove any information presented by the display device and present a blank screen, and then present a status message indicating the lost connectivity to the FIM avionics device. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/664739 |
| ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) Traffic Control Systems G08G 5/0021 (20130101) Original (OR) Class G08G 5/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10074764 | Stevenson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Thomas R. Stevenson (Rockville, Maryland); Manuel A. Balvin (Springfield, Virginia); Kevin L. Denis (Crofton, Maryland); John E. Sadleir (Washington, District of Columbia); Peter C. Nagler (College Park, Maryland) |
| ABSTRACT | A method of forming low-energy x-ray absorbers. Sensors may be formed on a semiconductor, e.g., silicon, wafer. A seed metal layer, e.g., gold, is deposited on the wafer and patterned into stem pads for electroplating. Stems, e.g., gold, are electroplated from the stem seed pads through a stem mask. An absorber layer, e.g., gold, is deposited on the wafer, preferably e-beam evaporated. After patterning the absorbers, absorber and stem mask material is removed, e.g., in a solvent bath and critical point drying. |
| FILED | Thursday, September 29, 2016 |
| APPL NO | 15/280369 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/083 (20130101) Measurement of Nuclear or X-radiation G01T 1/006 (20130101) G01T 1/36 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/027 (20130101) H01L 31/18 (20130101) Original (OR) Class H01L 31/085 (20130101) H01L 39/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075151 | Siles Perez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Jose Vicente Siles Perez (Pasadena, California); Choonsup Lee (La Palma, California); Goutam Chattopadhyay (Pasadena, California); Ken B. Cooper (Glendale, California); Imran Mehdi (South Pasadena, California); Robert H. Lin (Chino, California); Alejandro Peralta (Pasadena, California) |
| ABSTRACT | A solid state device chip including diodes (generating a higher frequency output through frequency multiplication of the input frequency) and a novel on-chip power combining design. Together with the on-chip power combining, the chip has increased efficiency because the diodes' anodes, being micro-fabricated simultaneously on the same patch of a GaAs wafer under identical conditions, are very well balanced. The diodes' GaAs heterostructure and the overall chip geometry are designed to be optimized for high power operation. As a result of all these features, the device can generate record-setting power having a signal frequency in the F-band and W-band (30% conversion efficiency). |
| FILED | Wednesday, November 25, 2015 |
| APPL NO | 14/952361 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8252 (20130101) H01L 23/66 (20130101) H01L 27/0814 (20130101) H01L 2223/6627 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Pulse Technique H03K 5/00006 (20130101) Original (OR) Class Transmission H04B 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075562 | Schnase et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | John L. Schnase (Laurel, Maryland); Daniel Q. Duffy (Gambrills, Maryland); Glenn S. Tamkin (Silver Spring, Maryland) |
| ABSTRACT | A system, method and computer-readable storage devices for providing a climate data analytic services application programming interface. The system includes a programming library that enables client device software to invoke the capabilities of a climate data analytics system through requests to various services supported by the climate data analytics system, and also includes a client-side communications interface that enables the programming library's methods to interact with a climate data analytics system's server interface to obtain access to the capabilities of the system. In one implementation, the programming library is implemented in the Python programming language. The programming library can include basic utilities that call a single, server-side method implemented by one of the various services supported by the climate data analytics system, and extended utilities that call a series of basic utilities and/or other extended utilities that have been placed under programmatic control in order to create client-side convenience methods and workflows. |
| FILED | Wednesday, May 13, 2015 |
| APPL NO | 14/711295 |
| ART UNIT | 2443 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/14 (20130101) H04L 67/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075678 | Kadari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Madhusudhan Kadari (Laurel, Maryland); Sergey Svoysky (Germantown, Maryland); Seshagiri Nadendla (Huntingtown, Maryland) |
| ABSTRACT | Disclosed is a satellite payload device, including a plurality of sensors configured to detect images of a satellite, a video distribution and storage unit configured to collect, compress, store, and transmit the images, and a control computer configured to request a portion of the plurality of sensors from which to receive sensor data that is routed to the video distribution and storage unit. |
| FILED | Tuesday, February 14, 2017 |
| APPL NO | 15/432469 |
| ART UNIT | 2426 — Cable and Television |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 7/181 (20130101) Original (OR) Class H04N 19/426 (20141101) H04N 21/4223 (20130101) H04N 21/6143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10070889 | Sutovsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter Sutovsky (Columbia, Missouri); Young-Joo Yi (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Peter Sutovsky (Columbia, Missouri); Young-Joo Yi (Columbia, Missouri) |
| ABSTRACT | The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst. |
| FILED | Thursday, May 29, 2014 |
| APPL NO | 14/290818 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Diagnosis; Surgery; Identification A61B 17/43 (20130101) Original (OR) Class Veterinary Instruments, Implements, Tools, or Methods A61D 19/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/061 (20130101) C12N 5/0604 (20130101) C12N 5/0609 (20130101) C12N 5/0612 (20130101) C12N 2500/05 (20130101) C12N 2517/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10071946 | Lew et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); School of Chemistry and Chemical Engineering, South China University of Technology (Guangzhou, Switzerland) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Helen N. Lew (Wynnewood, Pennsylvania); Karen Wagner (Ambler, Pennsylvania); Xuetong Fan (North Wales, Pennsylvania); Alberto Nunez (Dresher, Pennsylvania); Robert A. Moreau (Quakertown, Pennsylvania); Michael J. Haas (Wyndmoor, Pennsylvania); Zongcheng Yan (Guangzhou, China PRC) |
| ABSTRACT | Disclosed are methods for preparing phenolic branched chain fatty acids or alkyl esters thereof, involving subjecting in a pressurized container (a) at least one phenolic compound, (b) unsaturated fatty acids having 6 to 25 carbon atoms, alkyl esters thereof, or mixtures thereof, and (c) H-ferrierite zeolite catalyst in the presence of distilled water or alcohol and a nitrogen atmosphere at a temperature of about 100° C. to about 400° C. and a pressure of about 10 to about 1000 psi, and isolating saturated phenolic branched chain fatty acids or alkyl esters thereof or mixtures thereof. Also disclosed are methods for killing microorganisms on or in an object, involving contacting said object with an effective microorganisms killing amount of a composition comprising phenolic branched chain fatty acids or alkyl esters thereof, and optionally a carrier; the phenolic branched chain fatty acids or alkyl esters thereof may be produced by the methods described herein. |
| FILED | Tuesday, March 01, 2016 |
| APPL NO | 15/057632 |
| ART UNIT | 1671 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/02 (20130101) Acyclic or Carbocyclic Compounds C07C 51/353 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072046 | Vu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Hiep Lai Xuan Vu (Lincoln, Nebraska); Fernando Osorio (Lincoln, Nebraska); William W. Laegreid (Laramie, Wyoming); Asit K. Pattnaik (Lincoln, Nebraska); Fangrui Ma (Lincoln, Nebraska) |
| ABSTRACT | A non-naturally occurring porcine reproductive and respiratory syndrome virus (PRRSV) is provided herein, and methods of making and using the non-naturally occurring PRRSV also are provided. |
| FILED | Wednesday, March 25, 2015 |
| APPL NO | 15/127931 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/552 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/10021 (20130101) C12N 2770/10022 (20130101) C12N 2770/10034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10072381 | Fanta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | George F. Fanta (Morton, Illinois); Frederick C. Felker (Morton, Illinois); Gordon W. Selling (Dunlap, Illinois) |
| ABSTRACT | Disclosed are methods of increasing the surface hydrophobicity of the surface of a cellulosic article involving applying a solution of amylose-fatty ammonium salt inclusion complex in water to the article and then optionally applying an alkaline solution to the article to neutralize said amylose fatty ammonium salt inclusion complex to form an insoluble amylose fatty amine inclusion complex. Also disclosed are cellulosic articles produced by the methods. |
| FILED | Tuesday, September 27, 2016 |
| APPL NO | 15/277331 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 19/12 (20130101) Original (OR) Class D21H 21/16 (20130101) D21H 23/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10073775 | Wilerkson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Christopher B. Wilerkson (Portland, Oregon); Ren Wang (Portland, Oregon); Antoine Kaufmann (Hillsboro, Oregon); Anil Vasudevan (Portland, Oregon); Robert G. Blankenship (Tacoma, Washington); Venkata Krishnan (Ashland, Massachusetts); Tsung-Yuan C. Tai (Portland, Oregon) |
| ABSTRACT | An apparatus and method are described for a triggered prefetch operation. For example, one embodiment of a processor comprises: a first core comprising a first cache to store a first set of cache lines; a second core comprising a second cache to store a second set of cache lines; a cache management circuit to maintain coherency between one or more cache lines in the first cache and the second cache, the cache management circuit to allocate a lock on a first cache line to the first cache; a prefetch circuit comprising a prefetch request buffer to store a plurality of prefetch request entries including a first prefetch request entry associated with the first cache line, the prefetch circuit to cause the first cache line to be prefetched to the second cache in response to an invalidate command detected for the first cache line. |
| FILED | Friday, April 01, 2016 |
| APPL NO | 15/089035 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0808 (20130101) Original (OR) Class G06F 12/0811 (20130101) G06F 12/0862 (20130101) G06F 12/0891 (20130101) G06F 2212/602 (20130101) G06F 2212/1016 (20130101) G06F 2212/6022 (20130101) G06F 2212/6028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10073809 | Dinan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | James Dinan (Hudson, Massachusetts); Mario Flajslik (Hudson, Massachusetts) |
| ABSTRACT | Technologies for one-side remote memory access communication include multiple computing nodes in communication over a network. A receiver computing node receives a message from a sender node and extracts a segment identifier from the message. The receiver computing node determines, based on the segment identifier, a segment start address associated with a partitioned global address space (PGAS) segment of its local memory. The receiver computing node may index a segment table stored in the local memory or in a host fabric interface. The receiver computing node determines a local destination address within the PGAS segment based on the segment start address and an offset included in the message. The receiver computing node performs a remote memory access operation at the local destination address. The receiver computing node may perform those operations in hardware by the host fabric interface of the receiver computing node. Other embodiments are described and claimed. |
| FILED | Monday, April 27, 2015 |
| APPL NO | 14/696719 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/061 (20130101) G06F 3/067 (20130101) G06F 3/0659 (20130101) G06F 15/17331 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 10073026 | Curry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Commerce (Washington, District of Columbia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | John J. Curry (Frederick, Maryland); Zachary H. Levine (Rockville, Maryland) |
| ABSTRACT | A process for optically sorting a plurality of particles includes: providing a particle receiver; producing particles; receiving the particles by the particle receiver; receiving a light by the particle receiver; producing a standing wave optical interference pattern in an optical interference site of the particle receiver from the light; subjecting the particles to an optical gradient force from the standing wave optical interference pattern; deflecting the particles into a plurality of deflected paths to form the sorted particles from the particles; and propagating the sorted particles from the optical interference site through the deflected paths to optically sort the particles. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/632621 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1031 (20130101) G01N 15/1404 (20130101) G01N 15/1434 (20130101) Original (OR) Class G01N 2015/0038 (20130101) G01N 2015/0065 (20130101) G01N 2015/149 (20130101) G01N 2015/1081 (20130101) G01N 2015/1087 (20130101) G01N 2015/1493 (20130101) Optical Elements, Systems, or Apparatus G02B 17/004 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10072969 | Rhoads et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jeffrey Frederick Rhoads (West Lafayette, Indiana); George Tsu-Chih Chiu (West Lafayette, Indiana); Nikhil Bajaj (West Lafayette, Indiana); Andrew Burke Sabater (Claremont, California) |
| ABSTRACT | A device and method for sensing including a sensor having a functional surface layer located to interact with a material to be sensed, the sensor having an output that produces a signal responsive one or more of inertia, stiffness, acceleration, pressure, radiation, chemical compounds, and biological compounds; and further including electronics including: an input coupled to the sensor to receive a first signal therefrom; and a non-linearity provider that applies one or more non-linear operations to the input signal to generate a non-linear second signal. |
| FILED | Wednesday, February 07, 2018 |
| APPL NO | 15/890448 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 13/00 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/00 (20130101) G01P 15/097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10074000 | Kozicki |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Michael N. Kozicki (Phoenix, Arizona) |
| ABSTRACT | The disclosure features dendritic tags, and methods and systems for fabricating and using such tags. The methods can include obtaining at least one image of a dendritic tag attached to an article, analyzing the at least one image to identify a set of features associated with the dendritic tag, and comparing the set of features to stored information to identify the article. |
| FILED | Wednesday, March 12, 2014 |
| APPL NO | 14/775447 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 21/365 (20130101) G02B 27/286 (20130101) Electric Digital Data Processing G06F 17/3028 (20130101) G06F 17/30879 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1099 (20130101) Original (OR) Class G06K 9/46 (20130101) G06K 9/00147 (20130101) G06K 9/00577 (20130101) G06K 9/2027 (20130101) G06K 9/4671 (20130101) G06K 9/6202 (20130101) G06K 19/086 (20130101) G06K 19/06046 (20130101) G06K 19/07749 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 2207/10056 (20130101) G06T 2207/30024 (20130101) Ciphering or Deciphering Apparatus for Cryptographic or Other Purposes Involving the Need for Secrecy G09C 5/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) H04L 2209/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 10074068 | Irwin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Donald Eugene Irwin (Fredericksburg, Virginia); Gabriel Michael Yessin (Falls Church, Virginia); Joram Shenhar (Fairfax, Virginia); Joel Locknauth Dewnandan (Bladensburg, Maryland); Michael LeRoy Spears (Chantilly, Virginia); William Albert Tartal (Baltimore, Maryland) |
| ABSTRACT | Systems, devices and methods for storage, delivery, receipt, and/or other handling of an item in an electronically controllable storage receptacle are disclosed. The disclosure provides features for keyless access to the storage receptacle by use of user access information, such as a PIN or bar code. Further, features are disclosed for receiving and/or transmitting data related to the recipient and the item to facilitate the various handling actions of the item. |
| FILED | Thursday, June 18, 2015 |
| APPL NO | 14/743260 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0836 (20130101) Original (OR) Class G06Q 10/0837 (20130101) G06Q 50/32 (20130101) G06Q 2220/00 (20130101) Coin-freed or Like Apparatus G07F 5/18 (20130101) G07F 11/002 (20130101) G07F 17/12 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10074056 | Epstein |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ryan J. Epstein (Denver, Colorado) |
| ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| INVENTOR(S) | Ryan J. Epstein (Denver, Colorado) |
| ABSTRACT | Systems and methods are provided for performing noise-resilient quantum operations. A set of control signals are applied to a system to provide a first Hamiltonian for the system. The system includes an array of physical qubits and a plurality of coupling mechanisms configured such that each pair of neighboring physical qubits within the array is coupled by an associated coupling mechanism. The first Hamiltonian represents, for each coupling mechanism, a coupling strength between zero and a maximum value. An adiabatic interpolation of the Hamiltonian of the system from the first Hamiltonian to a second Hamiltonian is performed. The second Hamiltonian represents, for at least one of the plurality of coupling mechanisms, a coupling strength different from that of the first Hamiltonian. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/225210 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Original (OR) Class Pulse Technique H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10075067 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Ramot at Tel Aviv University Ltd. (Tel Aviv, Israel) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); RAMOT AT TEL AVIV UNIVERSITY LTD. (Tel Aviv, Israel) |
| INVENTOR(S) | Bin Wu (Irvine, California); Keyue Ma Smedley (Aliso Viejo, California); Sigmond Singer (Tel Aviv, Israel) |
| ABSTRACT | Various examples are provided for two-switch switched-capacitor (SC) converters. In one example, a SC converter includes first and second switches connected in series, a first gain-extension network coupled to the first switch and a second gain-extension network coupled to the second switch, which can be operated to boost a voltage applied across the first and second switches. The gain-extension networks can include a diode and a capacitor. In another example, the gain-extension networks can include a switch and a capacitor, which can be operated to buck a voltage applied across the gain-extension networks. In another example, a SC converter includes first and second diodes connected in series, a first gain-extension network coupled to the first diode and a second gain-extension network coupled to the second diode. The gain-extension networks can include a switch and a capacitor, which can be operated to buck a voltage applied across the gain-extension networks. |
| FILED | Monday, March 16, 2015 |
| APPL NO | 14/659216 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) Original (OR) Class H02M 2003/072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 11, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20180911.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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