FedInvent™ Patents

Patent Details for Tuesday, October 02, 2018 

This page was updated on Monday, March 27, 2023 at 05:38 AM GMT

Department of Health and Human Services (HHS) 

US 10085642 Frederick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Blaise Frederick (Belmont, Massachusetts);  Yunjie Tong (Melrose, Massachusetts)
ASSIGNEE(S) McLean Hospital Corporation (Belmont, Massachusetts)
INVENTOR(S) Blaise Frederick (Belmont, Massachusetts);  Yunjie Tong (Melrose, Massachusetts)
ABSTRACT The application features methods, devices, and systems for measuring blood flow in a subject. The computer-implemented methods include receiving functional magnetic resonance imaging (fMRI) data that provides information on at least one of volume or oxygenation of blood at one or more locations in a body over a first predetermined length of time. The methods also include receiving near-infrared spectroscopic (NIRS) imaging or measurement data representing at least one of blood concentration or oxygenation at a first portion of the body over a second predetermined length of time. The methods further include deriving, from the fMRI data corresponding to a second portion of the body, a time varying data set representing changes in blood oxygenation or volume or both blood oxygenation and volume at the second portion over the first predetermined length of time and determining, by a computing device, a time delay and a value of a similarity metric corresponding to a part of the spectroscopic imaging data that most closely matches the time varying data set. The time delay represents a difference between a first time in which blood flows from a third portion in the body to the first portion and a second time in which blood flows to the second portion from the third portion. The value of the similarity metric represents an amount of blood at the second portion. An estimate of a characteristic of at least one of blood flow or blood volume in the second portion at a given time is determined based on the time delay and the value of the similarity metric.
FILED Monday, June 06, 2011
APPL NO 13/701567
ART UNIT 3737 — Electrical Circuits and Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101) Original (OR) Class
A61B 5/0042 (20130101)
A61B 5/055 (20130101)
A61B 5/0075 (20130101)
A61B 5/0261 (20130101)
A61B 5/0263 (20130101)
A61B 5/0295 (20130101)
A61B 5/742 (20130101)
A61B 5/02014 (20130101)
A61B 5/02042 (20130101)
A61B 5/4064 (20130101)
A61B 5/4088 (20130101)
A61B 5/4244 (20130101)
A61B 5/4312 (20130101)
A61B 5/4842 (20130101)
A61B 5/4848 (20130101)
A61B 5/7203 (20130101)
A61B 5/7225 (20130101)
A61B 5/7278 (20130101)
A61B 5/14551 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085646 Feldman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Martin Feldman (Baton Rouge, Louisiana);  Dooyoung Hah (Baton Rouge, Louisiana)
ASSIGNEE(S) BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana)
INVENTOR(S) Martin Feldman (Baton Rouge, Louisiana);  Dooyoung Hah (Baton Rouge, Louisiana)
ABSTRACT A contact-type endoscope surface enhanced Raman scattering (SERS) probe includes a gradient-index (GRIN) lens, a transparent substrate adhered to the GRIN lens, and a rough metallic layer adhered to an opposite side of the transparent substrate from the GRIN lens. The GRIN lens focuses light from a Raman spectrometer onto the rough metallic layer, and the rough metallic layer is positioned at the distal end of the contact-type endoscope SERS probe.
FILED Tuesday, May 26, 2015
APPL NO 14/721953
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/002 (20130101)
A61B 1/06 (20130101)
A61B 1/0011 (20130101)
A61B 1/0661 (20130101)
A61B 5/0075 (20130101) Original (OR) Class
A61B 5/0084 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/44 (20130101)
G01J 3/0205 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/658 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085655 Narayan et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Topera, Inc. (Menlo Park, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia);  Topera, Inc. (Menlo Park, California)
INVENTOR(S) Sanjiv Narayan (La Jolla, California);  Carey Robert Briggs (La Jolla, California);  Ruchir Sehra (Scottsdale, Arizona)
ABSTRACT A system and method are provided for identifying a driver of a source associated with a heart rhythm disorder. Data are accessed from a plurality of sensors representing biological activity in the heart. A local first region of the heart that has repeating activation and determine whether the first region controls a second distant region of the heart for at least a predetermined number of beats is identified. The first local region is assigned as a driver of a source of the heart rhythm disorder, the source including the first local region and the second distant region.
FILED Friday, March 14, 2014
APPL NO 14/774120
ART UNIT 3766 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0006 (20130101)
A61B 5/044 (20130101)
A61B 5/0422 (20130101)
A61B 5/0452 (20130101)
A61B 5/02405 (20130101) Original (OR) Class
A61B 5/02444 (20130101)
A61B 5/04012 (20130101)
A61B 5/6852 (20130101)
A61B 2560/0475 (20130101)
A61B 2562/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085667 Couderc et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Rochester (Rochester, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Jean-Philippe Yves Couderc (Rochester, New York);  Mehmet Kemal Aktas (Penfield, New York);  Tolga Soyata (Pittsford, New York);  Alex Tyndall Page (Rochester, New York)
ABSTRACT An ECG clock electrocardiogram based diagnostic device and method is disclosed. The ECG clock provides a clear visual indicator of heart related anomalies such as Long QT syndrome over a longer span of time than can otherwise be assimilated by a medical practitioner. A variable such as QT interval is represented by a variable length radial hand similar to a watch or clock hand. The circular face of the ECG clock represents the diagnostic time interval, typically 24 hours. The resulting output or plot of the ECG clock portrays a circular or polar mapping of the heart related variable such as QT interval over the diagnostic time interval, facilitating rapid diagnosis of volumes of electrocardiogram data by a medical practitioner that has heretofore not been possible.
FILED Saturday, December 03, 2016
APPL NO 15/368587
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0006 (20130101)
A61B 5/044 (20130101)
A61B 5/0245 (20130101)
A61B 5/0452 (20130101) Original (OR) Class
A61B 5/04017 (20130101)
A61B 5/7203 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085689 Giuffrida et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Joseph P. Giuffrida (Hinckley, Ohio);  Dustin A. Heldman (Shaker Heights, Ohio);  Thomas O. Mera (Columbus, Ohio)
ASSIGNEE(S) Great Lakes NeuroTechnolgies Inc. (Cleveland, Ohio)
INVENTOR(S) Joseph P. Giuffrida (Hinckley, Ohio);  Dustin A. Heldman (Shaker Heights, Ohio);  Thomas O. Mera (Columbus, Ohio)
ABSTRACT The present invention is directed to a device and method for monitoring and assessment of movement disorder symptoms. The device and method disclosed herein are particularly amenable to remote monitoring of a subject's movement disorder symptoms. Briefly stated, in certain preferred embodiments of the present invention the movement disorder monitoring device accompanies a subject to a remote location where the device is used to record data relating to the severity of a subject's movement disorder symptoms over a period of time. This data is then subsequently used by physicians or other clinicians in optimizing and assessing treatment options directed at alleviating a subject's movement disorder symptoms. The method and device of the present invention can be used to monitor symptoms of a number of movement disorders including but not limited to dystonia, essential tremor, Huntington's disease, various ataxias, multiple sclerosis, psychogenic tremor, and Parkinson's disease.
FILED Friday, July 15, 2016
APPL NO 15/210990
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0022 (20130101)
A61B 5/0077 (20130101)
A61B 5/742 (20130101)
A61B 5/1101 (20130101)
A61B 5/4082 (20130101)
A61B 5/4848 (20130101) Original (OR) Class
A61B 5/6826 (20130101)
A61B 5/7405 (20130101)
A61B 2562/0219 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085862 Carman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Greg Carman (Los Angeles, California);  Daniel S. Levi (Pacific Palisades, California);  Mohanchandra Kotekar Panduranga (North Hills, California);  Fernando Vinuela (Los Angeles, California);  Abdon E. Sepulveda (Los Angeles, California)
ABSTRACT An apparatus and method for a micro-patterned thin film Nitinol (TFN) that is used as a cover for an expandable stent structure, and has elongation/expansion properties that are configured to match the elongation/expansion properties of the expandable stent structure is presented.
FILED Thursday, June 25, 2015
APPL NO 14/749930
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/07 (20130101)
A61F 2/90 (20130101)
A61F 2/91 (20130101)
A61F 2/915 (20130101) Original (OR) Class
A61F 2002/072 (20130101)
A61F 2002/823 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/35 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085969 Sparks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Robert Pleasants Sparks (Urbana, Illinois);  Wayne Charles Guida (St. Pete Beach, Florida);  Janet Lindsay DeHoff-Sparks (Pittsford, New York)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  University of Rochester (Rochester, New York)
INVENTOR(S) Robert Pleasants Sparks (Urbana, Illinois);  Wayne Charles Guida (St. Pete Beach, Florida);  Janet Lindsay DeHoff-Sparks (Pittsford, New York)
ABSTRACT Provided herein are compounds and formulations thereof that can be capable of binding to sortilin or an analog thereof. Also provided herein are methods of administering the compounds and formulation provided herein to a subject in need thereof.
FILED Monday, February 13, 2017
APPL NO 15/431568
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101) Original (OR) Class
A61K 31/167 (20130101)
A61K 31/381 (20130101)

Heterocyclic Compounds
C07D 207/09 (20130101)
C07D 333/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085975 Zaveri et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Astraea Therapeutics, LLC (Mountain View, California)
ASSIGNEE(S) Astraea Therapeutics, Inc. (Mountain View, California)
INVENTOR(S) Nurulain Zaveri (Saratoga, California);  Faming Jiang (Mountain View, California);  Lawrence Toll (Redwood City, California)
ABSTRACT Provided herein are novel and selective high affinity α3β4 nicotinic acetycholine receptor ligands and pharmaceutical compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, drug addiction or pain using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of selectively antagonizing receptors such as, for example, the α3β4 nicotinic acetycholine receptor using the compounds and compositions disclosed herein.
FILED Sunday, April 23, 2017
APPL NO 15/494505
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/439 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085981 Deschenes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida);  TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (Port St. Lucie, Florida)
ASSIGNEE(S) University of South Florida (Tamp, Florida);  Torrey Pines Institute for Molecular Studies (Port S. Lucie, Florida)
INVENTOR(S) Robert Joseph Deschenes (Tampa, Florida);  Marcello Angelo Giulianotti (Vero Beach, Florida);  Richard Allen Houghten (Port St. Lucie, Florida);  David Allen Mitchell (Lutz, Florida);  Laura Dawn Hamel (Temple Terrace, Florida)
ABSTRACT Embodiments of the present disclosure include compositions and pharmaceutical compositions that include protein acyl transferases (PAT) inhibitors, methods of treating a condition or disease, methods of treating autopalmitoylation activity, and the like.
FILED Wednesday, July 13, 2016
APPL NO 15/744399
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/496 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085988 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) SRI International (Menlo Park, California);  Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) SRI International (Menlo Park, California);  Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Tony Tianyi Wang (Harrisonburg, Virginia);  Shufeng Liu (Harrisonburg, Virginia);  Wenyu Wang (Boston, Massachusetts);  Neil Lajkiewicz (Garnet Valley, Pennsylvania);  John A. Porco, Jr. (Brookline, Massachusetts)
ABSTRACT A rocaglamide or a rocaglate derivative, particularly aglaroxin C, blocks hepatitis C virus (HCV) entry with improved potency and therapeutic index.
FILED Monday, September 19, 2016
APPL NO 15/269886
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/343 (20130101)
A61K 31/519 (20130101) Original (OR) Class
A61K 39/395 (20130101)

Heterocyclic Compounds
C07D 491/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085992 Strum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) G1 THERAPEUTICS, INC. (Research Triangle Park, North Carolina)
ASSIGNEE(S) G1 Therapeutics, Inc. (Research Triangle Park, North Carolina)
INVENTOR(S) Jay Copeland Strum (Hillsborough, North Carolina);  John Emerson Bisi (Apex, North Carolina);  Patrick Joseph Roberts (Durham, North Carolina);  Francis Xavier Tavares (Durham, North Carolina)
ABSTRACT This invention is in the area of improved compounds, compositions and methods of transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC) as well as renal cells, from damage associated with DNA damaging chemotherapeutic agents. In one aspect, improved protection of healthy cells is disclosed using disclosed compounds that act as highly selective and short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects undergoing DNA damaging chemotherapeutic regimens for the treatment of proliferative disorders.
FILED Thursday, November 03, 2016
APPL NO 15/342990
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101)
A61K 31/527 (20130101) Original (OR) Class
A61K 31/555 (20130101)
A61K 31/5377 (20130101)
A61K 31/7048 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 487/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10085997 Gallo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard L. Gallo (San Diego, California);  Teruaki Nakatsuji (San Diego, California)
ABSTRACT The disclosure provides for novel antimicrobial agents, methods of making, and methods of use thereof.
FILED Monday, April 10, 2017
APPL NO 15/483101
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 31/52 (20130101)
A61K 31/53 (20130101)
A61K 31/506 (20130101)
A61K 31/519 (20130101)
A61K 31/4188 (20130101)
A61K 31/5025 (20130101)
A61K 31/5365 (20130101)
A61K 31/5395 (20130101) Original (OR) Class
A61K 35/74 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 413/04 (20130101)
C07D 473/18 (20130101)
C07D 473/34 (20130101)
C07D 487/04 (20130101)
C07D 498/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086005 Finkelman et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Cincinnati (Cincinnati, Ohio);  U.S. Department of Veterans Affairs (Washington, District of Columbia);  Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S)
INVENTOR(S) Fred D. Finkelman (Cincinnati, Ohio);  Marat V. Khodoun (Mason, Ohio);  Suzanne C. Morris (Mason, Ohio)
ABSTRACT A method of treating a subject suffering from an allergic disorder is provided, the method including inducing rapid desensitization to an allergen, the rapid desensitization effectuated by: administering to the subject a plurality of equal doses of a first anti-FcεRIα monoclonal antibody, wherein the plurality of equal doses are administered over a 6 to 8 hour period and wherein each dose is lower than a level required to induce shock, thereby inducing rapid desensitization to the allergen. Monoclonal antibodies and methods of co-administering or consecutively administering a combination thereof to effectuate rapid desensitization are also provided.
FILED Friday, December 08, 2017
APPL NO 15/836095
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/137 (20130101)
A61K 31/335 (20130101)
A61K 31/506 (20130101)
A61K 31/573 (20130101) Original (OR) Class
A61K 31/675 (20130101)
A61K 31/4409 (20130101)
A61K 31/4439 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 16/4291 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086009 Wurtman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Richard J. Wurtman (Boston, Massachusetts);  Ingrid Richardson (Newton, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGIES (Cambridge, Massachusetts)
INVENTOR(S) Richard J. Wurtman (Boston, Massachusetts);  Ingrid Richardson (Newton, Massachusetts)
ABSTRACT This invention provides methods of enhancing brain development; increasing or enhancing intelligence; increasing or enhancing synthesis and levels of phospholipids, synapses, synaptic proteins, and synaptic membranes by a neural cell or brain cell, comprising contacting a subject or a pregnant or nursing mother thereof with a composition comprising an omega-3 fatty acid, an omega-6 fatty acid, and/or uridine, a metabolic precursor thereof, or a combination thereof.
FILED Tuesday, May 23, 2006
APPL NO 11/920915
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/14 (20130101)
A61K 31/14 (20130101)
A61K 31/202 (20130101)
A61K 31/202 (20130101)
A61K 31/7072 (20130101) Original (OR) Class
A61K 31/7072 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086013 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Yizhou Dong (Dublin, Ohio);  Kevin Thomas Love (Boston, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Daniel Griffith Anderson (Framingham, Massachusetts);  Delai Chen (Cambridge, Massachusetts);  Yi Chen (Cambridge, Massachusetts);  Arturo Jose Vegas (Belmont, Massachusetts);  Akinleye C. Alabi (Ithaca, New York);  Yunlong Zhang (Cambridge, Massachusetts)
ABSTRACT Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein:
wherein m, n, p, R′, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.
FILED Tuesday, November 01, 2016
APPL NO 15/340082
ART UNIT 1671 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/711 (20130101)
A61K 31/7105 (20130101) Original (OR) Class
A61K 47/22 (20130101)
A61K 2121/00 (20130101)

Heterocyclic Compounds
C07D 241/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086037 Das Gupta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Tapas Das Gupta (River Forest, Illinois);  Ananda Chakrabarty (Villa Park, Illinois);  Craig Beattie (Chicago, Illinois);  Tohru Yamada (Lombard, Illinois)
ASSIGNEE(S)
INVENTOR(S) Tapas Das Gupta (River Forest, Illinois);  Ananda Chakrabarty (Villa Park, Illinois);  Craig Beattie (Chicago, Illinois);  Tohru Yamada (Lombard, Illinois)
ABSTRACT The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The cargo compound may be a nucleic acid and specifically a DNA, RNA or anti-sense. The invention further discloses methods for treating cancer and diagnosing cancer.
FILED Monday, July 30, 2012
APPL NO 13/561225
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/164 (20130101) Original (OR) Class
A61K 47/64 (20170801)
A61K 47/549 (20170801)
A61K 49/0002 (20130101)
A61K 49/04 (20130101)
A61K 49/14 (20130101)
A61K 49/085 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 14/00 (20130101)
C07K 14/21 (20130101)
C07K 14/22 (20130101)
C07K 14/28 (20130101)
C07K 14/32 (20130101)
C07K 14/225 (20130101)
C07K 14/235 (20130101)
C07K 14/415 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/04 (20130101)
C12Q 1/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086041 Baker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Aaron B. Baker (Austin, Texas);  Subhamoy Das (Austin, Texas)
ABSTRACT Disclosed herein are compositions and articles for wound healing that contain proteovesicles, comprising a syndecan polypeptide embedded in a lipid vesicle, and a PDGF polypeptide. Also disclosed is the use of these compositions to enhance wound healing.
FILED Wednesday, December 21, 2016
APPL NO 15/387201
ART UNIT 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/127 (20130101)
A61K 9/1277 (20130101)
A61K 38/177 (20130101) Original (OR) Class
A61K 38/179 (20130101)
A61K 38/1858 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086057 Marconi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Virginia Commonwealth University (Richmond, Virginia)
ASSIGNEE(S) Virginia Commonwealth University (Richmond, Virginia)
INVENTOR(S) Richard T. Marconi (Richmond, Virginia);  Lee D. Oliver (Richmond, Virginia)
ABSTRACT Stage-specific Borrelia antigens for diagnosing, treating and/or preventing Lyme disease are provided. The antigens include chimeric Borrelia antigen constructs and mutant recombinant proteins comprising OspC and OspE epitopes, respectively. The antigens are used in multiprotein assays that differentiate early, middle and late stage infection, and/or in vaccine preparations.
FILED Thursday, October 08, 2015
APPL NO 15/517179
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0225 (20130101) Original (OR) Class

Peptides
C07K 14/20 (20130101)
C07K 14/435 (20130101)
C07K 2319/02 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/04 (20130101)
C12Q 1/68 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/569 (20130101)
G01N 33/56911 (20130101)
G01N 2333/20 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/57 (20180101)
Y02A 50/401 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086073 Hallahan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Dennis E. Hallahan (St. Louis, Missouri);  Shimian Qu (Brentwood, Tennessee);  Zhaozhong Han (Franklin, Tennessee)
ASSIGNEE(S) WASHINGTON UNIVERSITY (Saint Louis, Missouri)
INVENTOR(S) Dennis E. Hallahan (St. Louis, Missouri);  Shimian Qu (Brentwood, Tennessee);  Zhaozhong Han (Franklin, Tennessee)
ABSTRACT A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
FILED Friday, April 08, 2016
APPL NO 15/094579
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/03 (20130101)
A61K 38/08 (20130101)
A61K 41/00 (20130101) Original (OR) Class
A61K 41/0038 (20130101)
A61K 47/42 (20130101)
A61K 47/48246 (20130101)
A61K 47/48815 (20130101)
A61K 49/0002 (20130101)
A61K 49/08 (20130101)
A61K 49/14 (20130101)
A61K 51/08 (20130101)
A61K 51/082 (20130101)
A61K 51/088 (20130101)
A61K 51/1255 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)

Peptides
C07K 2/00 (20130101)
C07K 7/06 (20130101)
C07K 7/08 (20130101)
C07K 16/18 (20130101)
C07K 16/44 (20130101)
C07K 2317/622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086074 Lovell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
NIH Office of the Director (NIHOD)
APPLICANT(S) The Research Foundation for The State University of New York (Amherst, New York);  Health Research, Inc. (Buffalo, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York);  Health Research, Inc. (Buffalo, New York)
INVENTOR(S) Jonathan Lovell (Niagara Falls, Canada);  Ravindra Pandey (East Amherst, New York);  Kevin Carter (Amherst, New York);  Shuai Shao (Amherst, New York)
ABSTRACT Provided are compositions comprising porphyrin-phospholipid nanovesicles (PoP-NVs) which can be loaded with cargo. Methods for release of cargo from the PoP-NVs triggered by near infrared (NIR) light are also disclosed.
FILED Thursday, December 19, 2013
APPL NO 14/654085
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 9/1271 (20130101)
A61K 31/704 (20130101)
A61K 31/7048 (20130101)
A61K 41/0028 (20130101) Original (OR) Class
A61K 41/0071 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)
A61N 2005/0658 (20130101)

Heterocyclic Compounds
C07D 487/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086088 Head et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Brian P. Head (Lakeside, California);  Piyush M. Patel (La Jolla, California);  Hemal Patel (La Jolla, California);  David M. Roth (La Jolla, California)
ABSTRACT The invention provides an expression system for producing Caveolin-1 in neuronal cells or neural stem cells comprising a neuron-specific regulatory element and a nucleic acid sequence encoding Caveolin-1.
FILED Wednesday, January 28, 2015
APPL NO 14/608153
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 38/17 (20130101)
A61K 38/177 (20130101)
A61K 48/00 (20130101) Original (OR) Class
A61K 48/0058 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2740/16043 (20130101)
C12N 2830/002 (20130101)
C12N 2830/48 (20130101)
C12N 2840/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086092 Freeman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Matthew S. Freeman (Cincinnati, Ohio);  Bastiaan Driehuys (Chapel Hill, North Carolina)
ABSTRACT Systems, methods and related devices used to produce and collect polarized noble gas to inhibit, suppress, detect or filter alkali metal nanoclusters to preserve or increase a polarization level thereof. The systems can include a pre-sat chamber that has an Area Ratio between 20 and 500.
FILED Friday, February 20, 2015
APPL NO 15/120013
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/06 (20130101) Original (OR) Class
A61K 49/18 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 23/00 (20130101)
C01B 23/0036 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/282 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086094 Wei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) He Wei (Cambridge, Massachusetts);  Oliver T. Bruns (Boston, Massachusetts);  Ou Chen (Mansfield, Massachusetts);  Moungi G. Bawendi (Cambridge, Massachusetts)
ABSTRACT A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.
FILED Friday, September 11, 2015
APPL NO 14/852432
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/1839 (20130101) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086095 Steinmetz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Nicole Steinmetz (Cleveland, Ohio);  Michael Bruckman (Cleveland, Ohio)
ABSTRACT A rod-shaped plant virus having an interior surface and an exterior surface, and at least one imaging agent that is linked to the interior and/or exterior surface is described. The rod-shaped viruses can be combined into larger spherical nanoparticles. A rod-shaped plant virus or spherical nanoparticles including an imaging agent can be used in a method of generating an image of a tissue region of a subject such as a tumor or atherosclerotic tissue by administering the virus particle to the subject and generating an image of the tissue region of the subject to which the virus particle has been distributed.
FILED Wednesday, October 09, 2013
APPL NO 14/434435
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/1884 (20130101)
A61K 49/1896 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/00031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086108 Schneider et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia);  The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia);  The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Joel Schneider (Middletown, Maryland);  Gerald Brandacher (Baltimore, Maryland);  Daniel Smith (West Chester, Pennsylvania);  Gabriel Brat (Baltimore, Maryland);  Johanna Grahammer (Innsbruck, Austria)
ABSTRACT This disclosure provides novel hydrogels that can undergo multiple gel-sol transitions and methods of making and using such hydrogels, particularly in anastomosis procedures. The peptide hydrogels comprising a fibrillar network of peptides that are in an amphiphilic β-hairpin conformation. The peptides comprise photo-caged glutamate residues with a neutral photocage that can be photolytically selectively uncaged to disrupt the fibrillar network and trigger an irreversible gel-sol phase transition of the hydrogel. Isolated peptides for making the disclosed hydrogels are provided, as are methods of using the peptide hydrogels in anastomosis procedures.
FILED Friday, January 22, 2016
APPL NO 15/545647
ART UNIT 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/11 (20130101)
A61B 2017/1107 (20130101)
A61B 2017/1132 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 24/001 (20130101)
A61L 24/0031 (20130101) Original (OR) Class
A61L 24/108 (20130101)
A61L 2400/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086192 Halpern et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Modular Bionics Inc. (Santa Ana, California)
ASSIGNEE(S) Modular Bionics Inc. (Berkeley, California)
INVENTOR(S) Ian Loren Halpern (San Francisco, California);  Mark William Merlo (Santa Ana, California)
ABSTRACT Devices and methods for manipulating devices such as micro-scale devices are provided. The devices can include a tether of various materials surrounded by a stiff body. The tether interfaces with microscale devices to draw them against the stiff body, holding the microscale devices in a locked position for insertion into or extraction out of tissue. The tensional hook and stiff body are configurable in a multitude of positions and geometries to provide increased engagement. Such configurations allow for a range of implantation and extraction surgical procedures for the device within research and clinical settings.
FILED Thursday, July 07, 2016
APPL NO 15/204935
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/00234 (20130101)
A61B 2017/00345 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0529 (20130101) Original (OR) Class
A61N 1/3605 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087148 Ananthan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Subramaniam Ananthan (Birmingham, Alabama);  Richard B. Rothman (Baltimore, Maryland)
ASSIGNEE(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTE OF HEALTH (Washington, District of Columbia);  SOUTHERN RESEARCH INSTITUTE (Birmingham, Alabama)
INVENTOR(S) Subramaniam Ananthan (Birmingham, Alabama);  Richard B. Rothman (Baltimore, Maryland)
ABSTRACT The present disclosure relates to certain amine derivatives of fused bicyclic heterocycles that inhibit the amine reuptake function of the biogenic amine transporters, dopamine transporter (DAT), serotonin transporter (SERT) and norepinephrine transporter (NET). Compounds of the present disclosure are potent inhibitors of the reuptake of dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) with full or partial maximal efficacy. The compounds with partial maximal efficacy in inhibiting reuptake of all three biogenic amines are herein referred to as partial triple uptake inhibitors (PTRIs). Compounds of the present disclosure are useful for treating depression, pain and substance abuse and relapse to substance abuse and addiction to substances such as cocaine, methamphetamine, nicotine and alcohol. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, December 04, 2015
APPL NO 14/960023
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 239/94 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 403/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087149 Beeler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts);  DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts);  DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) Aaron Beaty Beeler (Cambridge, Massachusetts);  John A. Porco, Jr. (Brookline, Massachusetts);  Oscar J. Ingham (Boston, Massachusetts);  James E. Bradner (Weston, Massachusetts)
ABSTRACT Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that benefit from inhibition of HDAC8 activity.
FILED Friday, January 24, 2014
APPL NO 14/763013
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4192 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 249/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087151 Tsvetkov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (San Francisco, California)
ASSIGNEE(S) THE J. DAVID GLADSTONE INSTITUTES, A TESTIMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (San Francisco, California)
INVENTOR(S) Andrey S. Tsvetkov (Houston, Texas);  Steven M. Finkbeiner (Corte Madera, California);  Michael A. Pleiss (Sunnyvale, California);  Robert Greenhouse (Santa Clara, California)
ABSTRACT The present invention relates to compounds including but not limited to of any one of formulas Ia, Ib, IIa, IIb, IIIa, IIIb, and IV to VI, VIIa, VIIb, VIIIa, VIIIb and VIIIc as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.
FILED Thursday, January 08, 2015
APPL NO 15/110082
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/02 (20130101)
A61K 9/08 (20130101)
A61K 9/10 (20130101)
A61K 9/2059 (20130101)
A61K 9/4866 (20130101)

Heterocyclic Compounds
C07D 209/08 (20130101)
C07D 265/36 (20130101) Original (OR) Class
C07D 279/16 (20130101)
C07D 279/28 (20130101)
C07D 413/06 (20130101)
C07D 498/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087153 Frangioni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Curadel, LLC (Marlborough, Massachusetts)
ASSIGNEE(S) Curadel, LLC (Marlborough, Massachusetts)
INVENTOR(S) John V. Frangioni (Wayland, Massachusetts);  Paul Caffrey (North Falmouth, Massachusetts)
ABSTRACT Disclosed herein are methods for preparing ultrapure diaminophenothiasinium compounds with high solubility in solutions, e.g., water, and the compositions provided therefrom.
FILED Wednesday, December 21, 2016
APPL NO 15/387017
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 279/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087156 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California);  Xiamen University (Xiamen, China PRC)
ASSIGNEE(S) SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (San Diego, California);  XIAMEN UNIVERSITY (Xiamen, China PRC)
INVENTOR(S) Xiao-kun Zhang (San Diego, California);  Ying Su (San Diego, California);  Hu Zhou (San Diego, California);  Wen Liu (La Jolla, California);  Pei-Qiang Huang (Xiamen, China PRC)
ABSTRACT Provided herein are methods and compositions related to a retinoid receptor-selective pathway. As described herein, this pathway can be targeted to manipulate a tumor microenviroment. For example, the methods and compositions described herein can be used to induce apoptosis in a cancer cell. Further, the compositions described herein, including Sulindac and analogs thereof, can be used to target this pathway for the treatment or prevention of cancer in human patients.
FILED Thursday, February 16, 2017
APPL NO 15/435125
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/191 (20130101)

Acyclic or Carbocyclic Compounds
C07C 57/62 (20130101)
C07C 59/72 (20130101)
C07C 255/57 (20130101)

Heterocyclic Compounds
C07D 213/55 (20130101)
C07D 295/112 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)
G01N 2333/70567 (20130101)
G01N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087168 Golden et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Mental Health (NIMH)
APPLICANT(S) University of Kansas (Lawrence, Kansas);  University of Louisville Research Foundation, Inc. (Louisville, Kansas);  Southern Research Institute (Birmingham, Alabama)
ASSIGNEE(S) UNIVERSITY OF KANSAS (Lawrence, Kansas);  UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky);  SOUTHERN RESEARCH INSTITUTE (Birmingham, Alabama)
INVENTOR(S) Jennifer Golden (Olathe, Kansas);  Jeffrey Aube (Lawrence, Kansas);  Donghoon Chung (Louisville, Kentucky);  Chad Schroeder (Lawrence, Kansas);  Tuanli Yao (Lawrence, Kansas);  E. Lucile White (Birmingham, Alabama);  Nichole A. Tower (South Birmingham, Alabama)
ABSTRACT The present technology relates to compounds and compositions of Formulas I-III and methods using such compounds. The compounds and compositions described herein may be used in the treatment or prophylaxis of diseases associated with an alphavirus, for example, Venezuelan equine encephalitis virus (VEEV).
FILED Monday, February 27, 2017
APPL NO 15/443232
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 239/90 (20130101)
C07D 239/91 (20130101)
C07D 239/95 (20130101)
C07D 401/04 (20130101)
C07D 403/06 (20130101)
C07D 403/12 (20130101)
C07D 409/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087175 Hawkins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) William Hawkins (St. Louis, Missouri);  Robert Mach (St. Louis, Missouri);  Dirk Spitzer (St. Louis, Missouri);  Suwanna Vangveravong (St. Louis, Missouri);  Brian Van Tine (St. Louis, Missouri)
ABSTRACT Methods and compositions for treating cancers such as pancreatic cancer and synovial sarcoma are disclosed. Compounds comprising a sigma-2 receptor-binding moiety and a ferroptosis-inducing moiety are described. At least one described molecular species exhibits an IC50 value below 5 μM against human pancreatic cancer cells in vitro. Administration of this species promoted shrinkage of pancreatic cancer tumors in a murine model system in vivo, and led to 100% survival of experimental animals over a time course in which control therapies provided only 30% or 40% survival. Methods of synthesis of molecular species are also disclosed.
FILED Wednesday, April 01, 2015
APPL NO 15/301188
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/496 (20130101)
A61K 31/517 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 451/14 (20130101) Original (OR) Class
C07D 471/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087199 Erdmann et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Roman Erdmann (New Haven, Connecticut);  Alanna Schepartz Shrader (New Haven, Connecticut);  Derek Toomre (New Haven, Connecticut)
ABSTRACT The invention provides compositions that may be used for imaging intracellular structures. The invention further provides methods of imaging intracellular structures. In certain embodiments, the compositions of the invention include trans-cyclooctene-containing ceramide lipids and tetrazine-containing rhodamine-related dyes.
FILED Wednesday, October 21, 2015
APPL NO 14/919216
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0021 (20130101)
A61K 49/0052 (20130101)

Acyclic or Carbocyclic Compounds
C07C 271/34 (20130101)
C07C 2601/18 (20170501)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/0807 (20130101) Original (OR) Class
C07F 7/0816 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 11/28 (20130101)
C09B 57/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087206 Burke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Martin D. Burke (Champaign, Illinois);  Brice E. Uno (Champaign, Illinois);  Souvik Rakshit (Uluberia, India)
ABSTRACT Disclosed is a simplified, readily scalable series of individual methods that collectively constitute a method for the synthesis of C2′epiAmB, an efficacious and reduced-toxicity derivative of amphotericin B (AmB), beginning from AmB. Also provided are various compounds corresponding to intermediates in accordance with the series of methods.
FILED Friday, October 16, 2015
APPL NO 15/519471
ART UNIT 1673 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 1/00 (20130101)
C07H 17/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087210 Prakash et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Ionis Pharmaceuticals, Inc. (Carlsbad, California)
ASSIGNEE(S) Ionis Pharmaceuticals, Inc. (Carlsbad, California)
INVENTOR(S) Thazah P. Prakash (Carlsbad, California);  Punit P. Seth (Carlsbad, California);  Eric E. Swayze (Encinitas, California)
ABSTRACT The present invention provides modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom. More particularly, the present invention provides modified nucleosides and analogs thereof that are useful for incorporation at the terminus of an oligomeric compound. Such oligomeric compounds can also be included in a double stranded composition. In some embodiments, the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA.
FILED Thursday, March 17, 2016
APPL NO 15/073386
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/10 (20130101)
C07H 19/20 (20130101)
C07H 19/067 (20130101)
C07H 19/167 (20130101)
C07H 21/00 (20130101) Original (OR) Class
C07H 21/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/1135 (20130101)
C12N 15/1137 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/31 (20130101)
C12N 2310/315 (20130101)
C12N 2310/318 (20130101)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
C12N 2310/345 (20130101)
C12N 2310/346 (20130101)
C12N 2310/3231 (20130101)
C12N 2320/30 (20130101)
C12N 2320/51 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087211 Runyon et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
INVENTOR(S) Scott P. Runyon (Hillsborough, North Carolina);  Michael Rogawski (Sacramento, California);  Edgar Cook (Fairfax Station, Virginia);  John Kepler (Raleigh, North Carolina);  Hernan Navarro (Chapel Hill, North Carolina);  Rafal Kaminski (Waterloo, Belgium);  Matthew Orr (Raleigh, North Carolina)
ABSTRACT This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.
FILED Wednesday, November 02, 2016
APPL NO 15/341573
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Steroids
C07J 7/00 (20130101)
C07J 31/003 (20130101)
C07J 41/0005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087224 Zhou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Ping Zhou (Fresh Meadows, New York);  Costantino Iadecola (New York, New York)
ABSTRACT The present invention provides compositions and methods to treat Alzheimer's disease and other neurodegenerative diseases and conditions by expressing exogenous prohibitin in the neurons of the brain of the subject.
FILED Friday, October 31, 2014
APPL NO 14/530049
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/4702 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2750/14143 (20130101)
C12N 2750/14171 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087230 Parkhurst et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Maria R. Parkhurst (Ellicott City, Maryland);  Richard A. Morgan (Columbia, Maryland);  Steven A. Rosenberg (Potomac, Maryland);  Shannon Faith Rosati (Richmond, Virginia)
ABSTRACT The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for NY-ESO-1. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a mammal and a method of treating or preventing cancer in a mammal using the inventive TCRs or related materials.
FILED Friday, September 16, 2016
APPL NO 15/267285
ART UNIT 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 7/08 (20130101)
C07K 14/7051 (20130101) Original (OR) Class
C07K 16/18 (20130101)
C07K 16/2809 (20130101)
C07K 16/3069 (20130101)
C07K 2317/20 (20130101)
C07K 2317/21 (20130101)
C07K 2319/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101)
G01N 2333/7051 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087239 Chan-Hui et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
U.S. Agency for International Development (USAID)
APPLICANT(S) Theraclone Sciences, Inc. (Seattle, Washington);  The Scripps Research Institute (La Jolla, California);  International AIDS Vaccine Initiative (New York, New York)
ASSIGNEE(S) THERACLONE SCIENCES, INC. (Seattle, Washington);  THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California);  INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York)
INVENTOR(S) Po-Ying Chan-Hui (Bellevue, Washington);  Katherine Doores (San Diego, California);  Michael Huber (Zurich, Switzerland);  Stephen Kaminsky (Bronx, New York);  Steven Frey (Redmond, Washington);  Ole Olsen (Everett, Washington);  Jennifer Mitcham (Redmond, Washington);  Matthew Moyle (Redmond, Washington);  Sanjay K. Phogat (Edison, New Jersey);  Dennis R. Burton (La Jolla, California);  Laura Majorie Walker (San Diego, California);  Pascal Raymond Georges Poignard (San Diego, California);  Wayne Koff (Stony Brook, New York);  Melissa Danielle De Jean De St. Marcel Simek-Lemos (Brooklyn, New York)
ABSTRACT The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies may be characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided.
FILED Thursday, May 12, 2016
APPL NO 15/152630
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/1063 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087252 Sheppard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Dean Sheppard (Oakland, California);  George Su (San Francisco, California);  Amha Atakilit (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Dean Sheppard (Oakland, California);  George Su (San Francisco, California);  Amha Atakilit (Oakland, California)
ABSTRACT The present invention provides compositions and methods for treating and preventing disease associated with αvβ5 integrin by blocking binding to αvβ5 integrin. In particular, antibodies specific for αvβ5 integrin are useful for preventing, treating, and reversing sepsis.
FILED Monday, July 26, 2010
APPL NO 13/386323
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/2839 (20130101) Original (OR) Class
C07K 16/2848 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087256 Banchereau et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) BAYLOR RESEARCH INSTITUTE (Dallas, Texas)
ASSIGNEE(S) Baylor Research Institute (Dallas, Texas)
INVENTOR(S) Jacques F. Banchereau (Montclair, New Jersey);  Gerard Zurawski (Midlothian, Texas);  Sandra Zurawski (Midlothian, Texas);  SangKon Oh (Baltimore, Maryland)
ABSTRACT The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccine and antigen delivery vectors, to delivery antigens to antigen presenting cells. In one embodiment, the vector is an anti-CD40 antibody, or fragments thereof, and one or more antigenic peptides linked to the anti-CD40 antibody or fragments thereof, including humanized antibodies.
FILED Monday, January 09, 2017
APPL NO 15/401856
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 2039/6056 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 16/2878 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/54 (20130101)
C07K 2317/55 (20130101)
C07K 2317/56 (20130101)
C07K 2317/74 (20130101)
C07K 2317/80 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2317/626 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/16222 (20130101)
C12N 2740/16322 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087407 Dennis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Robert G. Dennis (Chapel Hill, North Carolina);  John A. van Aalst (Walton, Kentucky)
ABSTRACT Methods, devices and systems are disclosed for vibration induced tissue engineering. Apparatuses, devices, systems and methods are provided for engineering a tissue from stem cells using vibratory signals. A tissue engineering apparatus, device, or system can include a transmitter configured to transmit a signal to a receiver, a receiver configured to receive a signal from a transmitter, a holding structure configured to hold one or more mesenchymal stem cells (MSC), and a vibratory actuator in communication with the receiver and configured to generate a vibratory signal that is applied to the MSC.
FILED Thursday, March 10, 2016
APPL NO 15/066506
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/02 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/3691 (20130101)
A61L 27/3817 (20130101)
A61L 27/3821 (20130101)
A61L 27/3895 (20130101)
A61L 2430/02 (20130101)
A61L 2430/06 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101) Original (OR) Class
C12M 25/14 (20130101)
C12M 35/02 (20130101)
C12M 35/04 (20130101)
C12M 41/46 (20130101)
C12M 41/48 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0654 (20130101)
C12N 5/0655 (20130101)
C12N 5/0665 (20130101)
C12N 2506/1369 (20130101)
C12N 2527/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087417 Freed et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) William J. Freed (Bowie, Maryland);  Chun-Ting Lee (Miami, Florida)
ASSIGNEE(S)
INVENTOR(S) William J. Freed (Bowie, Maryland);  Chun-Ting Lee (Miami, Florida)
ABSTRACT Disclosed herein are methods for differentiation of neuronal cells from stem cells, which produce a three-dimensional model of the neocortex structure. In some embodiments, the methods include culturing stem cells with at least one inhibitor of SMAD signaling and at least one inhibitor of fibroblast growth factor signaling for a period of time to result in formation of an embryoid body. The embryoid body is then cultured with at least one FGF (for example, basic FGF) for a period of time sufficient to produce a neuroepithelial (NE) rosette. The rosette is then isolated and cultured in suspension or adherent culture in the presence of at least one FGF for a period of time sufficient to produce cells with dorsal cortical identity and those cells are then cultured in the substantial absence of trophic factors for a period of time sufficient to form a neocortical organoid.
FILED Friday, April 22, 2016
APPL NO 15/136250
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0618 (20130101) Original (OR) Class
C12N 2501/91 (20130101)
C12N 2501/115 (20130101)
C12N 2501/119 (20130101)
C12N 2501/155 (20130101)
C12N 2503/04 (20130101)
C12N 2506/02 (20130101)
C12N 2506/45 (20130101)
C12N 2513/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087420 Turner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Taiga Biotechnologies, Inc. (Aurora, Colorado)
ASSIGNEE(S) TAIGA BIOTECHNOLOGIES, INC. (Aurora, Colorado)
INVENTOR(S) Brian Curtis Turner (Denver, Colorado);  Yosef Refaeli (Denver, Colorado);  Gregory Bird (Littleton, Colorado)
ABSTRACT Disclosed are methods for manipulating and expanding stem cell populations, including adult stem cells, the cells produced by such methods, and various protein constructs related thereto.
FILED Friday, June 10, 2016
APPL NO 15/179735
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/82 (20130101)
C07K 14/4747 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0647 (20130101) Original (OR) Class
C12N 7/00 (20130101)
C12N 2501/22 (20130101)
C12N 2501/26 (20130101)
C12N 2501/48 (20130101)
C12N 2501/125 (20130101)
C12N 2501/145 (20130101)
C12N 2501/606 (20130101)
C12N 2501/998 (20130101)
C12N 2501/2303 (20130101)
C12N 2501/2306 (20130101)
C12N 2510/04 (20130101)
C12N 2740/15033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087422 Ingber et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Donald E. Ingber (Boston, Massachusetts);  Kevin Kit Parker (Waltham, Massachusetts);  Geraldine A. Hamilton (Cambridge, Massachusetts);  Anthony Bahinski (Wilmington, Delaware)
ABSTRACT Disclosed herein are organ chips that can be individually used or integrated together to form different microphysiological systems, e.g., for use in cell culturing, drug screening, toxicity assays, personalized therapeutic treatment, scaffolding in tissue repair and/or replacement, and/or pharmacokinetic or pharmacodynamics studies.
FILED Monday, December 10, 2012
APPL NO 14/363105
ART UNIT 1799 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)
C12M 23/34 (20130101)
C12M 25/02 (20130101)
C12M 35/04 (20130101)
C12M 35/08 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0697 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087429 Paul
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Surojit Paul (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Surojit Paul (Albuquerque, New Mexico)
ABSTRACT A novel peptide sequence that is a modified derivative of a neuron-specific tyrosine phosphatase is shown and described. Specifically, the novel peptide sequence is a modified derivative of striatal-enriched tyrosine phosphatase (STEP). The peptide sequence has been modified so as to be able to ameliorate and treat brain injury resulting from excessive glutamate release and/or oxidative stress. Examples of the types of brain injury which the presently disclosed peptide sequence is useful for treating includes acute brain injury resulting from stroke or traumatic brain injury and chronic disorders such as Huntington's chorea and schizophrenia. Furthermore, the presently described peptide sequence may further be useful in the treatment and amelioration of disorders associated with fear memory such as post-traumatic stress disorder.
FILED Tuesday, May 26, 2015
APPL NO 14/721024
ART UNIT 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/465 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101) Original (OR) Class

Enzymes
C12Y 301/03048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087435 Francklyn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (Burlington, Vermont)
ASSIGNEE(S) University of Vermont and State Agricultural College (Burlington, Vermont)
INVENTOR(S) Christopher Francklyn (Burlington, Vermont);  Karen M. Lounsbury (Essex Junction, Vermont);  Jason Botten (Williston, Vermont)
ABSTRACT The invention includes, in part, methods and compounds for treating diseases and conditions characterized by elevated threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to diseases and conditions in which angiogenesis is elevated as compared to normal. In some embodiments of the invention, a level of a TARS molecule is determined and compared to a control level of TARS to assess a treatment for a disease or condition characterized by elevated TARS activity.
FILED Wednesday, July 24, 2013
APPL NO 14/416356
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7125 (20130101)
A61K 38/53 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 16/40 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/99 (20130101) Original (OR) Class

Enzymes
C12Y 601/01003 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/502 (20130101)
G01N 33/6893 (20130101)
G01N 2333/9015 (20130101)
G01N 2800/7014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087436 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ronald A. Li (Davis, California);  Deborah K. Lieu (Davis, California)
ABSTRACT Methods to prepare electrophysiology mature cells from immature cells are provided, without the need for genetic manipulation.
FILED Thursday, February 05, 2015
APPL NO 14/615291
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/34 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087442 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Methodist Hospital (Houston, Texas)
ASSIGNEE(S) The Methodist Hospital (Houston, Texas)
INVENTOR(S) Haifa Shen (Houston, Texas);  Mauro Ferrari (Houston, Texas);  Jianliang Shen (Houston, Texas);  Mingzhen Zhang (Houston, Texas)
ABSTRACT Disclosed are methods and compositions containing functionalized nanoporous silicon particles, useful in a variety of diagnostic and/or therapeutic regimens for delivery of genetic constructs to one or more cells, tissues, and/or organs of interest. Also provided are methods for introducing into selected host cells one or more selected nucleic acid molecules. The present disclosure is also directed to a method of treating a tumor, comprising the step of administering to an individual one or more of the compositions and formulations thereof as described herein.
FILED Friday, December 11, 2015
APPL NO 14/967165
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5031 (20130101)
A61K 9/5146 (20130101)
A61K 31/713 (20130101)
A61K 31/7088 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087443 Schaefer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York);  THE ROCKEFELLER UNIVERSITY (New York, New York)
ASSIGNEE(S) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York);  THE ROCKEFELLER UNIVERSITY (New York, New York)
INVENTOR(S) Anne Schaefer (New York, New York);  Paul Greengard (New York, New York)
ABSTRACT The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
FILED Tuesday, October 28, 2014
APPL NO 15/032255
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101)
A01K 67/0276 (20130101)
A01K 2217/052 (20130101)
A01K 2217/075 (20130101)
A01K 2217/203 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0356 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/185 (20130101)
A61K 49/0008 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/141 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/321 (20130101)
C12N 2310/341 (20130101)
C12N 2310/346 (20130101)
C12N 2310/3515 (20130101)
C12N 2310/3521 (20130101)
C12N 2310/3521 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5058 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087444 Du
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
APPLICANT(S) Luqin Du (San Antonio, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Luqin Du (San Antonio, Texas)
ABSTRACT Certain embodiments are directed to methods of identifying neuroblastoma differentiation-inducing compounds or agent and their use in treating neuroblastoma.
FILED Friday, February 13, 2015
APPL NO 15/118551
ART UNIT 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087445 Behlke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Integrated DNA Technologies, Inc. (Coralville, Iowa)
ASSIGNEE(S) Integrated DNA Technologies, Inc. (Coralville, Iowa)
INVENTOR(S) Mark Aaron Behlke (Coralville, Iowa);  Richard Owczarzy (Coralville, Iowa);  Yong You (Iowa City, Iowa);  Joseph Alan Walder (Chicago, Illinois);  Kim Lennox (North Liberty, Iowa)
ABSTRACT The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.
FILED Wednesday, November 23, 2016
APPL NO 15/360382
ART UNIT 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/141 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/344 (20130101)
C12N 2310/352 (20130101)
C12N 2310/3529 (20130101)
C12N 2320/51 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6876 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087463 Fraser et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Department of Agriculture (USDA)
APPLICANT(S) Malcolm J. Fraser (Granger, Indiana);  Xu Li (Sharon, Massachusetts)
ASSIGNEE(S) University of Notre Dame Du Lac (Notre Dame, Indiana)
INVENTOR(S) Malcolm J. Fraser (Granger, Indiana);  Xu Li (Sharon, Massachusetts)
ABSTRACT The present invention provides a method for transforming an insect genome that has a much enhanced transformation frequency. The vectors and plasmids employed in the method are further described as transposition vectors that include a minimal amount of nucleotide sequence homologous to a 5′ region and a 3′ region of a native piggyBac nucleic acid sequence. The transformed cells or embryos may also be developed into transgenic organisms. Disclosed are minimal piggyBac-based plasmid constructs that comprises a minimal nucleic acid sequence homologous to a 5′ end of a piggyBac nucleic acid sequence (about 60-80 bp, particularly 66 bp) and a relatively long (300 to about 380 bp, particularly 311 bp or 378 bp) continuous nucleic acid sequence homologous to a 3′ end of a piggyBac native nucleic acid sequence. Methods employing these constructs include the use of a helper plasmid. Transformation frequencies employing the constructs are enhanced 100-fold or higher over that transformation frequency obtained using other than the herein described constructs.
FILED Monday, June 19, 2006
APPL NO 11/454947
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101) Original (OR) Class
C12N 15/90 (20130101)
C12N 2800/90 (20130101)
C12N 2800/204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087465 Beaucage et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
APPLICANT(S) The United States of America, as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Serge L. Beaucage (Silver Spring, Maryland);  Harsh V. Jain (Silver Spring, Maryland)
ABSTRACT Compounds of the formula
(Z)x wherein: each Z is independently selected from 2′-deoxythymidinyl moiety, 2′-deoxyadenosinyl moiety, and a 2′-deoxycytidinyl moiety, x is an integer from 5-20, wherein said 2′-deoxythymidinyl moieties are connected by thiophosphate triester linkages, and 3-12 of said thiophosphate triester linkages being positively charged linkages of the formula: where n is an integer from 2 to 6; and the remainder of the thiophosphate triester linkages are neutral linkages of the formula: provided that when x is 5-6, the number of positively charged linkages is 3, when x is 7-8, the number of positively charged linkages is 3-4, when x is 9-12, the number of positively charged linkages is 3-10, and when x is 13-20, the number of positively charged linkages is 4-12.
FILED Wednesday, September 14, 2016
APPL NO 15/265436
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 15/87 (20130101)
C12N 15/113 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/3181 (20130101)
C12N 2310/3233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087485 Muir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Tom W. Muir (Princeton, New Jersey);  Uyen T. T. Nguyen (Princeton, New Jersey);  Manuel M. Mueller (Princeton, New Jersey)
ABSTRACT Compositions and methods are provided for DNA barcoding of designer mononucleosome and polynucleosome (chromatin array) libraries for use, for example, for the profiling of chromatin readers, writers, erasers, and modulators thereof.
FILED Thursday, June 06, 2013
APPL NO 14/405303
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/48 (20130101)
C12Q 1/6876 (20130101) Original (OR) Class

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 20/04 (20130101)
C40B 30/04 (20130101)
C40B 30/08 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6875 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087486 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  SAGE BIONETWORKS (Seattle, Washington)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Sage Bionetworks (Seattle, Washington)
INVENTOR(S) Kang Zhang (La Jolla, California);  Gregory Hannum (La Jolla, California);  Trey Ideker (La Jolla, California);  Stephen H Friend (Seattle, Washington);  Justin Guinney (Seattle, Washington)
ABSTRACT The invention provides for methods for predicting age of a subject based on the epigenome of the subject.
FILED Tuesday, November 12, 2013
APPL NO 14/442089
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6881 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/136 (20130101)
C12Q 2600/154 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5308 (20130101)
G01N 33/57484 (20130101)
G01N 2500/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088461 Cooks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Zheng Ouyang (West Lafayette, Indiana)
ABSTRACT The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
FILED Wednesday, September 20, 2017
APPL NO 15/710072
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/91 (20130101)
G01N 30/95 (20130101) Original (OR) Class
G01N 33/49 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088478 Dai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Hongjie Dai (Cupertino, California);  Scott M. Tabakman (Palo Alto, California);  Guosong Hong (Stanford, California);  Bo Zhang (Stanford, California)
ABSTRACT Disclosed are nanostructured gold films which may be produced by solution-phase depositions of gold ions onto a variety of surfaces. The resulting plasmonic gold films are used for enhanced spectroscopic-based immunoassays in multiplexed microarray format with detection mechanisms based on either surface-enhanced Raman scattering or near-infrared fluorescence enhancement. The preparation of the films and subsequent modifications of the gold film surfaces afford increased sensitivity for various microarrays. The films are discontinuous, forming gold “islands.” Sensitivity, size, shape, and density of the nanoscopic gold islands comprising the discontinuous nanostructured gold film are controlled to enhance the intensity of Raman scattering and fluorescence in the near-infrared, allowing for improved measurements in clinical diagnostic or biomedical research applications.
FILED Tuesday, March 10, 2015
APPL NO 14/644075
ART UNIT 1677 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/658 (20130101)
G01N 33/553 (20130101) Original (OR) Class
G01N 2610/00 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24851 (20150115)
Y10T 428/24909 (20150115)
Y10T 428/24917 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088484 Ribbeck et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Katharina Ribbeck (Cambridge, Massachusetts);  Nicole Lynn Kavanaugh (Cambridge, Massachusetts);  Julia Yin-Ting Co (Cambridge, Massachusetts);  Erica Shapiro (Cambridge, Massachusetts)
ABSTRACT A method of altering intercellular interactions between a combination of microorganisms includes contacting a combination of different species of microorganisms with at least one mucin. Isolated compositions include a combination of microorganisms and at least one mucin. One microorganism of the combination inhibits cell growth or promotes cell death of at least one other microorganism of a different species in the combination. The combination of microorganisms with the mucin results an increase in cell growth or a reduction in cell death, respectively, of the at least one other microorganism.
FILED Tuesday, May 09, 2017
APPL NO 15/590749
ART UNIT 1675 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/02 (20130101)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 29/065 (20160801)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0014 (20130101)
A61K 9/20 (20130101)
A61K 9/0053 (20130101)
A61K 35/74 (20130101)
A61K 38/14 (20130101)
A61K 38/1735 (20130101)
A61K 47/42 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/16 (20130101)
C12N 1/20 (20130101)
C12N 1/38 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/68 (20130101) Original (OR) Class
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088537 Pendse et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Mihir R. Pendse (Fremont, California);  Brian K. Rutt (Stanford, California)
ABSTRACT A method for providing SAR focusing at a target in a body using an MRI system is provided. A computed pulse is provided at a lower power to the body. A MR thermometry is performed. A map is created from the MR thermometry to determine if a hotspot aligns with the target. If the target does not align with the hotspot, then the steps are performed comprising, recomputing the computed pulse, providing the computed pulse at a lower power to the body, performing MR thermometry, creating a map from the MR thermometry to determine if a hotspot aligns with the target, and repeating these steps until the hotspot aligns with the target. The computed pulse is applied at a higher power to the body to provide the desired SAR at the target. Temperature change is monitored with MR thermometry the previous two steps are repeated until desired temperature is achieved.
FILED Wednesday, May 13, 2015
APPL NO 14/711484
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/403 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/31 (20130101)
G01R 33/288 (20130101) Original (OR) Class
G01R 33/3415 (20130101)
G01R 33/4804 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089423 Qiang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) BO Qiang (Rochester, Minnesota);  Matthew W Urban (Rochester, Minnesota)
ABSTRACT Described here are systems and methods for efficiently simulating wave propagation in one or more viscoelastic media. The systems and methods described here implement an elastodynamic model that includes memory variables for one or more viscoelastic properties. Boundary conditions can also be generated based on a perfectly matched layer (PML) condition. A hybrid implicit/explicit method is used to generate wave simulation data. In this method, equations related to the memory variables and PML are solved using an implicit integrator, and other equations in the elastodynamic model are solved using an explicit method.
FILED Monday, May 23, 2016
APPL NO 15/161440
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 17/5009 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 10085716 Romano et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) J. Jordan Romano (Boston, Massachusetts);  Elizabeth N. Bearrick (Cambridge, Massachusetts);  Lauren R. Hernley (Cambridge, Massachusetts);  Saul A Lopez (Los Angeles, California);  Laura M. Tanenbaum (Cambridge, Massachusetts);  Marcel A. C. Thomas (Cambridge, Massachusetts);  Teddy A. Toussaint (Cambridge, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) J. Jordan Romano (Boston, Massachusetts);  Elizabeth N. Bearrick (Cambridge, Massachusetts);  Lauren R. Hernley (Cambridge, Massachusetts);  Saul A Lopez (Los Angeles, California);  Laura M. Tanenbaum (Cambridge, Massachusetts);  Marcel A. C. Thomas (Cambridge, Massachusetts);  Teddy A. Toussaint (Cambridge, Massachusetts)
ABSTRACT An apparatus and a method for sheathing a medical device, tool, instrument or probe (generally, probe) is provided. Among other aspects, a probe support jig capable of supporting the probe is provided, which includes a mechanical coupling for accepting a sheath on a sheath shell. In use, the sheath shell is coupled at one end thereof to the support jig and the probe is fed into the sheath, which is coupled to the sheath shell at another end thereof.
FILED Monday, March 17, 2014
APPL NO 14/215269
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00142 (20130101)
A61B 8/4281 (20130101)
A61B 8/4422 (20130101) Original (OR) Class
A61B 46/10 (20160201)
A61B 50/20 (20160201)
A61B 2562/247 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/00 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49817 (20150115)
Y10T 29/53961 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086061 Thomas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Army, on behalf of the Walter Reed Army Institute of Research (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Army, on behalf of the Walter Reed Army Institute of Research (Washington, District of Columbia)
INVENTOR(S) Stephen J. Thomas (Rockville, Maryland);  Kenneth H. Eckels (Rockville, Maryland);  Joseph R. Putnak (Silver Spring, Maryland)
ABSTRACT Immunogenic compositions comprising one or more inactivated dengue viruses and one or more inactivated non-dengue flaviviruses and methods of making and using thereof are provided.
FILED Thursday, March 10, 2016
APPL NO 15/550433
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 39/395 (20130101)
A61K 2039/70 (20130101)
A61K 2039/545 (20130101)
A61K 2039/5252 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/24034 (20130101)
C12N 2770/24051 (20130101)
C12N 2770/24134 (20130101)
C12N 2770/24151 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/39 (20180101)
Y02A 50/386 (20180101)
Y02A 50/388 (20180101)
Y02A 50/392 (20180101)
Y02A 50/394 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086094 Wei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) He Wei (Cambridge, Massachusetts);  Oliver T. Bruns (Boston, Massachusetts);  Ou Chen (Mansfield, Massachusetts);  Moungi G. Bawendi (Cambridge, Massachusetts)
ABSTRACT A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.
FILED Friday, September 11, 2015
APPL NO 14/852432
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/1839 (20130101) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086105 Guo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Providence Health System Oregon (Portland, Oregon)
ASSIGNEE(S) Providence Health System Oregon (Portland, Oregon)
INVENTOR(S) Jian Xin Guo (Portland, Oregon);  Kenton W. Gregory (Portland, Oregon)
ABSTRACT The invention provides a solid foam wound dressing useful for hemorrhage control and wound repair, as well as methods for making such a wound dressing.
FILED Tuesday, September 08, 2015
APPL NO 14/847526
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/00012 (20130101)
A61F 13/00063 (20130101)
A61F 13/00987 (20130101)
A61F 13/00991 (20130101)
A61F 13/15577 (20130101)
A61F 2013/0054 (20130101)
A61F 2013/0071 (20130101)
A61F 2013/0074 (20130101)
A61F 2013/0091 (20130101)
A61F 2013/00106 (20130101)
A61F 2013/00314 (20130101)
A61F 2013/00472 (20130101)
A61F 2013/00719 (20130101)
A61F 2013/00757 (20130101)
A61F 2013/00931 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/28 (20130101) Original (OR) Class
A61L 15/28 (20130101)
A61L 15/44 (20130101)
A61L 15/425 (20130101)
A61L 2300/404 (20130101)
A61L 2300/408 (20130101)
A61L 2300/412 (20130101)
A61L 2300/418 (20130101)
A61L 2400/04 (20130101)
A61L 2430/34 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 44/005 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2005/00 (20130101)
B29K 2105/045 (20130101)
B29K 2995/0037 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/753 (20130101)

Compositions of Macromolecular Compounds
C08L 5/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086334 Tour et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) William Marsh Rice University (Houston, Texas)
ASSIGNEE(S) WILLIAM MARSH RICE UNIVERSITY (Houston, Texas)
INVENTOR(S) James M. Tour (Bellaire, Texas);  Ruquan Ye (Houston, Texas);  Andrew Metzger (Houston, Texas);  Macy Stavinoha (Weimar, Texas);  Yonghao Zheng (Houston, Texas)
ABSTRACT Embodiments of the present disclosure pertain to scalable methods of producing carbon quantum dots with desired bandgaps by the following steps: exposing a carbon source to an oxidant at a reaction temperature, where the exposing results in the formation of the carbon quantum dots; and selecting a desired size of the formed carbon quantum dots. In some embodiments, the selecting occurs by at least one of separating the desired size of the formed carbon quantum dots from other formed carbon quantum dots; selecting the reaction temperature that produces the desired size of the formed carbon quantum dots; and combinations of such steps. The desired size of carbon quantum dots can include a size range. The methods of the present disclosure can also include a step of purifying the formed carbon quantum dots prior to selecting a desired size.
FILED Friday, June 19, 2015
APPL NO 15/320201
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 61/145 (20130101) Original (OR) Class
B01D 2315/10 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/05 (20170801)
C01B 32/182 (20170801)
C01B 2204/32 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2004/62 (20130101)
C01P 2004/64 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/65 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086372 Thompson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Guy Thompson (Watertown, Massachusetts);  Daniel Levner (Boston, Massachusetts);  Christopher David Hinojosa (Cambridge, Massachusetts)
ABSTRACT Described herein are fluid-flow control devices for transferring a fluid from a place to another and/or controlling a fluid flow. In some embodiments, fluid-flow control devices described herein can be used as pumping devices to transfer a fluid by peristaltic motion and/or as valve devices to control fluid flow for various applications, e.g., in a microfluidic platform.
FILED Tuesday, December 10, 2013
APPL NO 14/650735
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101) Original (OR) Class
B01L 2200/10 (20130101)
B01L 2200/025 (20130101)
B01L 2200/027 (20130101)
B01L 2300/123 (20130101)
B01L 2300/0848 (20130101)
B01L 2400/082 (20130101)
B01L 2400/0481 (20130101)
B01L 2400/0655 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/00 (20130101)

Positive-displacement Machines for Liquids; Pumps
F04B 19/006 (20130101)
F04B 43/12 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086431 Bagge-Hansen et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) Lawrence Livermoe National Security, LLC (Livermore, California);  National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Michael Bagge-Hansen (San Leandro, California);  Patrick G. Campbell (Oakland, California);  Jeffrey D. Colvin (Pleasanton, California);  Sergei Kucheyev (Oakland, California);  Thomas E. Felter (Livermore, California)
ABSTRACT Disclosed here is a method for making a nanoporous material, comprising aerosolizing a solution comprising at least one metal salt and at least one solvent to obtain an aerosol, freezing the aerosol to obtain a frozen aerosol, and drying the frozen aerosol to obtain a nanoporous metal compound material. Further, the nanoporous metal compound material can be reduced to obtain a nanoporous metal material.
FILED Tuesday, June 16, 2015
APPL NO 14/741334
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0018 (20130101) Original (OR) Class
B22F 1/0022 (20130101)
B22F 9/026 (20130101)
B22F 9/082 (20130101)
B22F 2009/084 (20130101)
B22F 2009/0824 (20130101)
B22F 2009/0832 (20130101)
B22F 2009/0844 (20130101)
B22F 2009/0864 (20130101)
B22F 2201/013 (20130101)
B22F 2201/20 (20130101)
B22F 2202/03 (20130101)
B22F 2301/10 (20130101)
B22F 2301/255 (20130101)
B22F 2304/05 (20130101)
B22F 2304/10 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 40/00 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086654 Manesh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Ali Manesh (Chicago, Illinois);  Mike Tercha (Wausau, Wisconsin);  Brian Anderson (Wausau, Wisconsin);  Brian J. Meliska (Wausau, Wisconsin);  Fidelis Ceranski (Wausau, Wisconsin)
ASSIGNEE(S) Bridgestone Americas Tire Operations, LLC (Nashville, Tennessee)
INVENTOR(S) Ali Manesh (Chicago, Illinois);  Mike Tercha (Wausau, Wisconsin);  Brian Anderson (Wausau, Wisconsin);  Brian J. Meliska (Wausau, Wisconsin);  Fidelis Ceranski (Wausau, Wisconsin)
ABSTRACT A non-pneumatic tire for supporting a load by working in tension comprising a generally annular inner ring, a generally annular outer ring, and an interconnected web having a plurality of web elements and comprising a plurality of generally polygonal openings. Web elements are sized, oriented and comprised of a material that facilitates buckling when subjected to a compressive load. By buckling, those elements in a deformed portion of the tire between a wheel and a footprint region where the tire contacts a surface can assume a significantly reduced portion of the load, if any. This causes web elements in other portions of the interconnected web to operate in tension to support the load.
FILED Wednesday, December 21, 2011
APPL NO 13/333721
ART UNIT 3617 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Vehicle Tyres Tyre Inflation; Tyre Changing or Repairing; Repairing, or Connecting Valves To, Inflatable Elastic Bodies in General; Devices or Arrangements Related to Tyres
B60C 7/00 (20130101)
B60C 7/14 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 152/10378 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086922 Jansen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Jan T. Jansen (Florissant, Missouri);  Ryan Stott (Cedar Hill, Missouri);  William Vallellanes (St. Louis, Missouri);  Jack Van Es (St. Charles, Missouri)
ABSTRACT A stringer for having a runout with a raised area configured to reduces stress while improving drainage across the runout when utilized in a close structural component of a vehicle such as an aileron of an aircraft. In one or more configurations, the raised area of the runout of the stringer includes multiple tapered surfaces adjacent to one another oriented and configured as ramps to collectively guide water up, over and down the raised area of the stringer.
FILED Friday, December 06, 2013
APPL NO 14/099048
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 3/00 (20130101)

Aeroplanes; Helicopters
B64C 1/064 (20130101) Original (OR) Class
B64C 3/182 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 1/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087156 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California);  Xiamen University (Xiamen, China PRC)
ASSIGNEE(S) SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (San Diego, California);  XIAMEN UNIVERSITY (Xiamen, China PRC)
INVENTOR(S) Xiao-kun Zhang (San Diego, California);  Ying Su (San Diego, California);  Hu Zhou (San Diego, California);  Wen Liu (La Jolla, California);  Pei-Qiang Huang (Xiamen, China PRC)
ABSTRACT Provided herein are methods and compositions related to a retinoid receptor-selective pathway. As described herein, this pathway can be targeted to manipulate a tumor microenviroment. For example, the methods and compositions described herein can be used to induce apoptosis in a cancer cell. Further, the compositions described herein, including Sulindac and analogs thereof, can be used to target this pathway for the treatment or prevention of cancer in human patients.
FILED Thursday, February 16, 2017
APPL NO 15/435125
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/191 (20130101)

Acyclic or Carbocyclic Compounds
C07C 57/62 (20130101)
C07C 59/72 (20130101)
C07C 255/57 (20130101)

Heterocyclic Compounds
C07D 213/55 (20130101)
C07D 295/112 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)
G01N 2333/70567 (20130101)
G01N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087205 Yaghi et al.
FUNDED BY
Department of Defense (DOD)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Omar M. Yaghi (Berkeley, California);  Mitsuharu Suzuki (Albany, California);  Hexiang Deng (Berkeley, California);  Lisa Wang (Los Angeles, California)
ABSTRACT The disclosure provides for metal organic frameworks (MOFs) which comprise a plurality of SBUs comprising different metals or metal ions and/or a plurality of organic linking moieties comprising different functional groups.
FILED Friday, March 27, 2015
APPL NO 15/128225
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/204 (20130101)
B01D 2257/108 (20130101)
B01D 2257/504 (20130101)
B01D 2257/7025 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101)
B01J 31/1691 (20130101)
B01J 2531/22 (20130101)
B01J 2531/23 (20130101)
B01J 2531/24 (20130101)
B01J 2531/25 (20130101)
B01J 2531/26 (20130101)
B01J 2531/27 (20130101)
B01J 2531/72 (20130101)
B01J 2531/842 (20130101)
B01J 2531/845 (20130101)
B01J 2531/847 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 3/02 (20130101)
C07F 19/005 (20130101) Original (OR) Class

Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 11/005 (20130101)
F17C 11/007 (20130101)
F17C 2221/012 (20130101)
F17C 2221/013 (20130101)
F17C 2221/033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087213 Chen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
ASSIGNEE(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S) Zhilei Chen (College Station, Texas);  Miguel A. Ramirez (Dunedin, New Zealand);  Dongli Guan (College Station, Texas)
ABSTRACT The present invention includes methods, compositions, uses, and kits for purifying a protein of interest (POI) comprising contacting a first fusion protein comprising the POI fused to the C-terminus of an intein C-fragment with a second fusion protein comprising an intein N-fragment and a purification tag to form a complex between the first fusion protein and the second fusion protein, cleaving the POI from the intein C-fragment, wherein the protein is released from the complex; and isolating the POI; the present invention also includes fusion proteins and vector.
FILED Friday, January 10, 2014
APPL NO 14/760392
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 1/14 (20130101) Original (OR) Class
C07K 1/22 (20130101)
C07K 1/32 (20130101)
C07K 2319/20 (20130101)
C07K 2319/92 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)

Enzymes
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087422 Ingber et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Donald E. Ingber (Boston, Massachusetts);  Kevin Kit Parker (Waltham, Massachusetts);  Geraldine A. Hamilton (Cambridge, Massachusetts);  Anthony Bahinski (Wilmington, Delaware)
ABSTRACT Disclosed herein are organ chips that can be individually used or integrated together to form different microphysiological systems, e.g., for use in cell culturing, drug screening, toxicity assays, personalized therapeutic treatment, scaffolding in tissue repair and/or replacement, and/or pharmacokinetic or pharmacodynamics studies.
FILED Monday, December 10, 2012
APPL NO 14/363105
ART UNIT 1799 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)
C12M 23/34 (20130101)
C12M 25/02 (20130101)
C12M 35/04 (20130101)
C12M 35/08 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0697 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087440 Lofquist et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Micronics, Inc. (Redmond, Washington)
ASSIGNEE(S) Micronics, Inc. (Redmond, Washington)
INVENTOR(S) Alan K. Lofquist (Kirkland, Washington);  C. Frederick Battrell (Wenatchee, Washington);  Heather K. Bouzek (Seattle, Washington)
ABSTRACT An integrated “lab-on-a-chip” microfluidic device performs nucleic acid sample preparation and diagnostic analysis from test samples containing cells and/or particles. The device analyzes DNA or RNA targets, or both, from a common test sample. Dried and/or liquid reagents necessary for nucleic acid sample preparation and analysis are contained on the device, such that the device only requires addition of test sample. Clay mineral and alkaline buffer reagents are employed for overcoming the problems of nucleic acid degradation and contamination during sample preparation. The device may include a composite filter to separate plasma or serum from other blood constituents when the test sample is a blood product. The microfluidic device utilizes a plurality of microfluidic channels, inlets, valves, membranes, pumps, and other elements arranged in various configurations to manipulate the flow of the liquid sample, in particular, in order to prepare nucleic acids and perform further diagnostic analysis.
FILED Wednesday, May 07, 2014
APPL NO 14/889374
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502753 (20130101)
B01L 2300/087 (20130101)
B01L 2300/0681 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0864 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0481 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1017 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087442 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Methodist Hospital (Houston, Texas)
ASSIGNEE(S) The Methodist Hospital (Houston, Texas)
INVENTOR(S) Haifa Shen (Houston, Texas);  Mauro Ferrari (Houston, Texas);  Jianliang Shen (Houston, Texas);  Mingzhen Zhang (Houston, Texas)
ABSTRACT Disclosed are methods and compositions containing functionalized nanoporous silicon particles, useful in a variety of diagnostic and/or therapeutic regimens for delivery of genetic constructs to one or more cells, tissues, and/or organs of interest. Also provided are methods for introducing into selected host cells one or more selected nucleic acid molecules. The present disclosure is also directed to a method of treating a tumor, comprising the step of administering to an individual one or more of the compositions and formulations thereof as described herein.
FILED Friday, December 11, 2015
APPL NO 14/967165
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5031 (20130101)
A61K 9/5146 (20130101)
A61K 31/713 (20130101)
A61K 31/7088 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087443 Schaefer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York);  THE ROCKEFELLER UNIVERSITY (New York, New York)
ASSIGNEE(S) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York);  THE ROCKEFELLER UNIVERSITY (New York, New York)
INVENTOR(S) Anne Schaefer (New York, New York);  Paul Greengard (New York, New York)
ABSTRACT The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.
FILED Tuesday, October 28, 2014
APPL NO 15/032255
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101)
A01K 67/0276 (20130101)
A01K 2217/052 (20130101)
A01K 2217/075 (20130101)
A01K 2217/203 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0356 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/185 (20130101)
A61K 49/0008 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/141 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/321 (20130101)
C12N 2310/341 (20130101)
C12N 2310/346 (20130101)
C12N 2310/3515 (20130101)
C12N 2310/3521 (20130101)
C12N 2310/3521 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5058 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087444 Du
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
APPLICANT(S) Luqin Du (San Antonio, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Luqin Du (San Antonio, Texas)
ABSTRACT Certain embodiments are directed to methods of identifying neuroblastoma differentiation-inducing compounds or agent and their use in treating neuroblastoma.
FILED Friday, February 13, 2015
APPL NO 15/118551
ART UNIT 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087446 Sharp
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Telemedicine and Advanced Technology Research Center (TATRC)
APPLICANT(S) ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York)
ASSIGNEE(S) Albert Einstein College of Medicine, Inc. (Bronx, New York)
INVENTOR(S) David Sharp (Scardale, New York)
ABSTRACT Methods and compositions are provided for inhibiting or treating metastasis based on discoveries regarding Kif19 and Cep192. Methods and compositions are provided for enhancing wound healing, treating fibrosis, reducing scarring and treating nerve pain.
FILED Monday, September 18, 2017
APPL NO 15/706849
ART UNIT 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/4738 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)

Enzymes
C12Y 306/04004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087504 Kamplain et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea)
ASSIGNEE(S) SAMSUNG ELECTRONICS CO., LTD. (Gyeonggi-Do, South Korea)
INVENTOR(S) Justin W. Kamplain (Bartlesville, Oklahoma);  Keeve Gurkin (Somerville, Massachusetts);  Peter Allen (Boston, Massachusetts)
ABSTRACT A method for preparing semiconductor nanocrystals comprising indium arsenide is disclosed. The method includes heating a first mixture including nanocrystal seeds comprising indium arsenide with an absorbance in a range from about 700 to 800 nm and a liquid medium in a reaction vessel to a first temperature; and combining the nanocrystals seeds comprising indium arsenide with an indium-source mixture and an arsenic-source mixture under conditions suitable to increase the size of the seeds to form the semiconductor nanocrystals comprising indium arsenide, wherein the indium-source mixture includes an indium precursor, a coordinating solvent, and a carboxylic acid; and the arsenic-source mixture includes a liquid medium and an arsenic precursor represented by the formula As(Y(R)3)3, where Y is Ge, Sn, or Pb; and each R, independently, is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, heterocyclyl, aryl, or heteroaryl, wherein each R, independently, is optionally substituted by 1 to 6 substituents independently selected from hydrogen, halo, hydroxy, nitro, cyano, amino, alkyl, cycloalkyl, cycloalkenyl, alkoxy, acyl, thio, thioalkyl, alkenyl, alkynyl, cycloalkenyl, heterocyclyl, aryl, or heteroaryl. Semiconductor nanocrystals are also disclosed.
FILED Monday, June 13, 2016
APPL NO 15/180656
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 28/026 (20130101)

Alloys
C22C 1/007 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087512 Imundo, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S) The Timken Company (North Canton, Ohio)
ASSIGNEE(S) The Timken Company (North Canton, Ohio)
INVENTOR(S) John R. Imundo, Jr. (Kensington, Connecticut);  Vikram M. Bedekar (Canton, Ohio);  Edward F Damm (Akron, Ohio);  R. Scott Hyde (Massillon, Ohio)
ABSTRACT A steel article with resistance to contact fatigue having a martensitic stainless steel body with a hardened surface layer and a core. The hardened surface layer is tempered martensite and M7C3 carbides, has at least 1.6 wt. % carbon, and has a depth equal to or greater than the depth where the steel article experiences the maximum shear stress when placed in service. Also, a method of manufacturing such as a steel article having resistance to contact fatigue comprising: providing a martensitic stainless steel article having a prior austenite grain size of ASTM #6 or smaller; carburizing the surface of the steel article; solution treating the steel article; tempering the steel article for a first time; hardening the steel article; cooling the steel article at a temperature below 0° F.; and tempering the steel article for a second time.
FILED Friday, March 15, 2013
APPL NO 14/421285
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/011 (20130101)

Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 1/06 (20130101)
C21D 1/18 (20130101)
C21D 6/004 (20130101)
C21D 6/04 (20130101)
C21D 6/005 (20130101)
C21D 6/007 (20130101)
C21D 6/008 (20130101)

Alloys
C22C 38/02 (20130101)
C22C 38/04 (20130101)
C22C 38/44 (20130101)
C22C 38/46 (20130101)
C22C 38/52 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 8/22 (20130101)
C23C 8/38 (20130101)
C23C 8/80 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087553 Nagarajan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Ramanathan Nagarajan (Newton, Massachusetts);  Christopher P Drew (Clinton, Massachusetts);  Charlene M Mello (Rochester, Massachusetts)
ABSTRACT A polymer-micelle complex suitable for use as an aid to preparing fibers, particularly nanofibers, by electrospinning. The polymer-micelle complex may be designed to impart viscosity, surface tension and conductivity properties optimal for electrospinning. By incorporating the complex as a secondary ingredient, one may electrospin sparingly soluble or low molecular weight polymers. Moreover, the polymer-micelle complex can be used as a generic carrier for preparing fibers incorporating other desired materials, such as rigid or globular (hard-to-spin) polymers, enzymes, cells, viral particles and nanoparticles.
FILED Thursday, April 12, 2018
APPL NO 15/951204
ART UNIT 1789 — Miscellaneous Articles, Stock Material
CURRENT CPC
Compositions of Macromolecular Compounds
C08L 89/00 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/003 (20130101) Original (OR) Class

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 4/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087884 Peters et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Donald W. Peters (Colchester, Connecticut);  James P. Bangerter (Manchester, Connecticut)
ABSTRACT Aspects of the disclosure are directed to a system of an aircraft, comprising: at least one fairing, a liner, and an actuator configured to cause the at least one fairing to be translated relative to the liner in order to obtain a modulation of a metering area between the liner and the at least one fairing.
FILED Wednesday, October 07, 2015
APPL NO 14/877607
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 33/04 (20130101)

Jet-propulsion Plants
F02K 1/08 (20130101)
F02K 1/09 (20130101)
F02K 1/822 (20130101)
F02K 1/1223 (20130101) Original (OR) Class
F02K 1/1292 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/672 (20130101)
Y02T 50/675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088161 Drake et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Christopher Drake (Atlanta, Georgia);  Stanislav Kostka, Jr. (Shrewsbury, Massachusetts);  Frank J. Cunha (Avon, Connecticut)
ABSTRACT A liner panel for use in a gas turbine engine. The liner panel has a hot side and a cold side. The liner panel includes a rail extending from the cold side and a multiple of studs extending from the cold side. At least one of the multiple of studs extends from, in part, the rail.
FILED Friday, August 29, 2014
APPL NO 15/038906
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/18 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/323 (20130101)
F05D 2230/60 (20130101)
F05D 2240/35 (20130101)
F05D 2260/201 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/002 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088166 Drake et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Christopher Drake (West Hartford, Connecticut);  Seth A. Max (Manchester, Connecticut);  Meggan Harris (Colchester, Connecticut)
ABSTRACT A swirler is provided for a gas turbine engine. The swirler includes a swirler body with a threaded section and a multiple of circumferentially arranged tabs operable to flex radially outward. The multiple of circumferentially arranged tabs are radially displaced from the threaded section.
FILED Thursday, May 15, 2014
APPL NO 14/904490
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 19/04 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/22 (20130101)
F02C 7/2365 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/10 (20130101)
F23R 3/14 (20130101)
F23R 3/28 (20130101) Original (OR) Class
F23R 3/60 (20130101)
F23R 2900/00012 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/671 (20130101)
Y02T 50/675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088238 Shedd
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Timothy A. Shedd (Middleton, Wisconsin)
ABSTRACT Disclosed are methods and apparatuses for cooling a work piece surface using two-phase impingement, such as direct jet impingement. Preferred method include flowing a coolant through a chamber comprising a surface to be cooled by projecting a jet stream of coolant against the surface while maintaining pressure in the chamber to permit at least a portion of coolant contacting the surface to boil. Preferred apparatuses include a chamber comprising the surface and tubular nozzles configured to project a stream of coolant against the surface, a pump for forcing coolant through the tubular nozzles, a pressurizer for maintaining an appropriate pressure in the chamber, and a heat exchanger for cooling the coolant exiting the chamber. The apparatuses may further include a pressure regulator for detecting changes in temperature of the coolant exiting the chamber and communicating with the pressurizer to adjust the maintained pressure accordingly. The methods and apparatuses disclosed herein provide for effective and efficient cooling or work piece surfaces.
FILED Monday, May 11, 2015
APPL NO 14/709096
ART UNIT 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction
F28C 3/08 (20130101) Original (OR) Class

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/427 (20130101)
H01L 23/4735 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088285 Hardt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lee R. Hardt (Ridgecrest, California);  Donald L. Burnett (Ridgecrest, California);  Josiah S. Garfield (Ridgecrest, California);  Robert A. Koontz (Anchorage, Alaska)
ABSTRACT Embodiments of the invention are directed to enhancing insensitive munitions performance. Some embodiments of the invention employ an outgassing pad having unique geometrical configurations and positioning. Other embodiments rely on using thermally-releasable components to foster billet expulsion. Additional embodiments combine both aspects into an entire cook-off mitigation system.
FILED Thursday, December 15, 2016
APPL NO 15/380738
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 12/20 (20130101)
F42B 12/22 (20130101)
F42B 12/207 (20130101) Original (OR) Class
F42B 39/14 (20130101)
F42B 39/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088288 Caska et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kevin Caska (Vernon, New Jersey);  Andrew Zimmer (Wharton, New Jersey)
ABSTRACT The munition employs an energetically initiated electromagnetic pulse through a coil which induces a voltage intended to be used for the operation of an electronic time delay circuit and subsequent ignition of a detonation device. Explosive energy from a primer is employed to move a generator core through a generator coil to induce the voltage. The voltage is supplied to a delay circuit. After a set time, the delay circuit supplies power to a laser igniter which detonates the munition. A striker assembly, in addition to initiating the primer, functions as an out of line safety as well as an electric safety.
FILED Friday, October 06, 2017
APPL NO 15/726626
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition Fuzes; Arming or Safety Means Therefor
F42C 11/04 (20130101) Original (OR) Class
F42C 11/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088292 Perea et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S) James D. Perea (Alexandria, Virginia);  Bradley W. Libbey (Alexandria, Virginia)
ABSTRACT A phase-resolved heterodyne shearing interferometer has been developed for high-rate, whole field observations of transient surface motion. The sensor utilizes polarization multiplexing and multiple carrier frequencies to separate each segment of a shearing Mach-Zehnder interferometer. Post-processing routines have been developed to recombine the segments by extracting the scattered object phase from Doppler shifted intermediate carrier frequencies, providing quantitative relative phase changes and information to create variable shear, phase resolved shearographic fringe patterns without temporal or spatial phase shifting.
FILED Wednesday, February 08, 2017
APPL NO 15/427079
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02007 (20130101)
G01B 9/02022 (20130101)
G01B 9/02032 (20130101) Original (OR) Class
G01B 9/02038 (20130101)
G01B 9/02084 (20130101)
G01B 9/02089 (20130101)
G01B 2290/70 (20130101)

Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 9/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088313 Young et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) TRX SYSTEMS, INC. (Greenbelt, Maryland)
ASSIGNEE(S) TRX SYSTEMS, INC. (Greenbelt, Maryland)
INVENTOR(S) Travis Young (Rockville, Maryland);  John Riley Miller (Hanover, Maryland);  John Karvounis (Bowie, Maryland);  Dan Hakim (Silver Spring, Maryland);  Jared Napora (Severn, Maryland);  Benjamin Funk (Hanover, Maryland);  Carole Teolis (Glenn Dale, Maryland)
ABSTRACT A method for computing a correction to a compass heading for a portable device worn or carried by a user is described. The method involves determining a heading for the device based on a compass reading, collecting data from one or more sensors, determining if the device is indoors or outdoors based on the collected data, and correcting the heading based on the determination of whether the device is indoors or outdoors.
FILED Tuesday, August 15, 2017
APPL NO 15/677897
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 17/38 (20130101) Original (OR) Class

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/0247 (20130101)
G01S 5/0252 (20130101)
G01S 5/0278 (20130101)
G01S 19/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088320 Ramlall
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Rohan Y. Ramlall (San Diego, California)
ABSTRACT A method for estimating the position of a mobile device. Initializing an Extended Kalman Filter. Moving mobile device from a first unknown position (xt1, yt1) at a first time t1 to a second unknown position (xt2, yt2) at a second time t2. Measuring distance traveled d and angle traveled θ between the first unknown position and the second unknown position. Calculating a first possible position (x1, y1) at the first time and a second possible position (x2, y2) the second time. Using the Extended Kalman Filter, a predicted first unknown position ({circumflex over (x)}, ŷ) is calculated at the first time. A first final value is calculated according to √{square root over (({circumflex over (x)}−x1)2+(ŷ−y1)2)}. A second final value is calculated according to √{square root over (({circumflex over (x)}−x2)2+(ŷ−y2)2)}. If the first final value is less than or equal to the second final value, the first possible position (x1, y1) is output. Otherwise, the second possible position (x2, y2) is output.
FILED Wednesday, May 16, 2018
APPL NO 15/981821
ART UNIT 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/165 (20130101) Original (OR) Class
G01C 25/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088324 Chen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Xiao Yan Chen (Beijing, China PRC);  Raghu K. Ganti (Elmsford, New York);  Sheng Huang (Shanghai, China PRC);  Kai Liu (Beijing, China PRC);  Ramya Raghavendra (White Plains, New York);  Mudhakar Srivatsa (White Plains, New York)
ABSTRACT A method, computer system, and computer readable product for trajectory data compression are disclosed. In embodiments, the method comprises generating spatial data for one or more moving objects; projecting the data onto a network comprised of a plurality of trajectories, the network constraining movement of the one or more moving objects; and storing the projected data in a data store. In embodiments of the invention, the method further comprises translating updates and queries to the spatial data, using specified data of the network, into links to the data store, and using the links to update and query the data store. In embodiments of the invention, the specified data of the network are stored in a network store. In embodiments of the invention, each of the trajectories includes one or more sub-trajectories, and the projecting the spatial data onto a network includes projecting the spatial data onto the sub-trajectories.
FILED Monday, May 02, 2016
APPL NO 15/144379
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3407 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088367 Larsen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S) HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey)
INVENTOR(S) Christopher Scott Larsen (Plymouth, Minnesota);  Brian Keith Olmsted (Richfield, Minnesota)
ABSTRACT A device for measuring body core temperature includes a light guide. The light guide is coupled to an earpiece. A first sensor is positioned at a first end of the light guide, and a second sensor is positioned at a second end of the light guide. A processor is coupled to the first sensor and the second sensor. The first sensor senses infrared radiation from an infrared source at the second end of the light guide, and the second sensor measures a temperature of the light guide at the second end of the light guide. The processor determines a temperature of the infrared source at the second end of the light guide by compensating for infrared radiation due to a thermal gradient of the light guide via a regression analysis across a range of ambient temperatures of the light guide.
FILED Wednesday, September 23, 2015
APPL NO 14/862743
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/0818 (20130101) Original (OR) Class

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 13/004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088414 Lipson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Michal Lipson (Ithaca, New York);  Alexander Gaeta (Ithaca, New York);  Austin G. Griffith (Ithaca, New York);  Jaime Cardenas (Ithaca, New York);  Ryan K. W. Lau (Ithaca, New York);  Yoshitomo Okawachi (Lansing, New York);  Romy Fain (Ithaca, New York)
ABSTRACT Techniques, systems, and devices are disclosed to provide on-chip integrated gas sensor based on photonic sensing. For example, a sensing device is provided to include an optical comb generator that produces an optical comb of different optical comb frequencies in a mid-infrared (MIR) spectral range to interact with a sample under detection, the optical comb generator including a substrate, an optical resonator formed on the substrate and an optical waveguide formed on the substrate and coupled to the optical resonator, and an optical detector that detects light from the sample at the different optical comb frequencies.
FILED Thursday, May 07, 2015
APPL NO 14/706935
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3504 (20130101) Original (OR) Class
G01N 2201/0612 (20130101)
G01N 2201/0635 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/105 (20130101)
H01L 31/0232 (20130101)
H01L 31/02327 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088476 Braun et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Vytrace Corporation (Export, Pennsylvania)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  Vytrace Corporation (Export, Pennsylvania)
INVENTOR(S) Paul V. Braun (Savoy, Illinois);  Gerald G. Cano (Export, Pennsylvania);  Chunjie Zhang (Champaign, Illinois)
ABSTRACT The invention relates to hydrogel and organogel sensors as well as their application to continuous analyte monitoring. The sensor can include a hydrogel or organogel matrix. Standard and inverse designed are provided. In one embodiment, the matrix can include a molecular recognition agent for an analyte (e.g., a glucose analyte), and a volume resetting agent that reversibly binds with the molecular recognition agent. Reversible crosslinks between the molecular recognition agent and volume resetting agent can change the volume of the matrix upon interacting with the analyte via a competitive binding process. In various embodiments, the invention provides a hydrogel-based glucose sensor and sensors for continuous glucose monitoring. The glucose sensor can be based on a glucose-responsive hydrogel with a volume linearly correlated with glucose concentrations, such as about 0.05-50 mM, under physiological conditions. The invention thus provides a blood glucose monitor suitable for use in clinical settings.
FILED Monday, September 29, 2014
APPL NO 15/027921
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/14532 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/66 (20130101)
G01N 33/542 (20130101)
G01N 33/544 (20130101)
G01N 33/54373 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088535 Shah
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) QuSpin, Inc. (Louiville, Colorado)
ASSIGNEE(S)
INVENTOR(S) Vishal Shah (Westminister, Colorado)
ABSTRACT A system and method is described to measure the magnetic field gradient using an optically pumped magnetometer configured as an intrinsic gradiometer. Atoms are prepared in a freely precessing coherent superposition of the magnetically sensitive hyperfine ground states in two or more physically separated locations. A probe laser beam is used to interrogate atoms in both locations. As the probe light beam passes through the coherent atoms, optical sidebands are self-generated at the ground state hyperfine frequency of the magnetically sensitive states. Each of the two sets of atoms produces distinct sidebands at a frequency separation proportional to the magnetic field experienced by each set of atoms. The probe light is captured using a photodetector. The self-generated probe optical sidebands interfere to produce a beat note whose frequency is proportional to the magnetic field gradient between the two sets of atoms. Measuring the frequency of the beat note therefore provides an accurate reading of the magnetic field gradient. An optical filter or a polarizer can be additionally used to remove the central frequency of the probe light, thus removing the noise produced by the residual probe beam.
FILED Wednesday, June 06, 2018
APPL NO 16/001633
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/26 (20130101) Original (OR) Class
G01R 33/032 (20130101)
G01R 33/1284 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088571 Vuorenkoski-Dalgleish et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) FLORIDA ATLANTIC UNIVERSITY (Boca Raton, Florida)
ASSIGNEE(S) FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida)
INVENTOR(S) Anni Vuorenkoski-Dalgleish (Vero Beach, Florida);  Fraser Dalgleish (Vero Beach, Florida);  Bing Ouyang (Vero Beach, Florida)
ABSTRACT Methods for characterizing scattering in a medium of a Light Detection And Ranging (LiDAR) system and systems therefrom are provided. A method includes obtaining off-axis power return characteristics with respect to a first wavelength of light and on-axis power return characteristics for at least the first wavelength of light. The method also includes estimating at least one beam attenuation coefficient (c) based on the off-axis power return characteristics and common volume parameter function for the LiDAR system and an extinction coefficient (α) for the medium based on the on-axis power return characteristics. The method further includes extracting a value for at least one diffuse attenuation coefficient (Kd) for the medium using a beam spread parameter for the LiDAR system (D) and a pre-defined relationship between α, c, D, and Kd.
FILED Wednesday, February 17, 2016
APPL NO 15/045980
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/538 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/497 (20130101)
G01S 17/003 (20130101)
G01S 17/10 (20130101)
G01S 17/88 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088663 Ozcan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Aydogan Ozcan (Los Angeles, California);  Euan McLeod (Alhambra, California)
ABSTRACT A method of forming nanolenses for imaging includes providing an optically transparent substrate having a plurality of particles disposed on one side thereof. The optically transparent substrate is located within a chamber containing therein a reservoir holding a liquid solution. The liquid solution is heated to form a vapor within the chamber, wherein the vapor condenses on the substrate to form nanolenses around the plurality of particles. The particles are then imaged using an imaging device. The imaging device may be located in the same device that contains the reservoir or a separate imaging device.
FILED Friday, May 13, 2016
APPL NO 15/154279
ART UNIT 2481 — Recording and Compression
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/60 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/12 (20130101)
C23C 14/223 (20130101)
C23C 14/541 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1468 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/361 (20130101)
G02B 21/365 (20130101) Original (OR) Class

Holographic Processes or Apparatus
G03H 1/0443 (20130101)
G03H 2001/046 (20130101)
G03H 2001/0447 (20130101)
G03H 2001/0452 (20130101)
G03H 2222/34 (20130101)
G03H 2240/56 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/881 (20130101)
Y10S 977/891 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088688 Mitchell
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Wavefront Research, Inc. (Bethlehem, Pennsylvania)
ASSIGNEE(S) WAVEFRONT RESEARCH, INC. (Northampton, Pennsylvania)
INVENTOR(S) Thomas A. Mitchell (Nazareth, Pennsylvania)
ABSTRACT An optical imager design that is capable of imaging a common scene to two or more optical systems, and is more compact in physical size and superior in throughput than previous designs is disclosed.
FILED Monday, February 13, 2017
APPL NO 15/430693
ART UNIT 2872 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/2823 (20130101)
G01J 2003/2826 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/30 (20130101)
G02B 27/141 (20130101)
G02B 27/1013 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089331 Sample et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John T. Sample (Pearl River, Louisiana);  Elias Z. K. Ioup (New Orleans, Louisiana)
ABSTRACT System and method for storing a dataset of image tiles. Method includes determining a number of zoom levels, accessing a cluster file that includes a subset of the zoom levels, and accessing the image tiles. For each of the image tiles, a cluster name is computed. For each of the image tiles, if the cluster file has a name that matches the computed cluster name, an image tile pointer is stored in a fixed length index, and the image tile associated with the computed cluster name is stored. For each of the image tiles, if the cluster file name does not match the computed cluster name, another subset of the zoom levels is computed, a new cluster file is created, an image tile pointer is created and stored, and the image tile is stored associated with the computed cluster name in the new cluster file according to the image tile pointer.
FILED Tuesday, June 09, 2015
APPL NO 14/734250
ART UNIT 2454 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 17/3028 (20130101) Original (OR) Class
G06F 17/30011 (20130101)
G06F 17/30091 (20130101)
G06F 17/30244 (20130101)
G06F 17/30286 (20130101)
G06F 17/30339 (20130101)

Image Data Processing or Generation, in General
G06T 1/60 (20130101)
G06T 3/40 (20130101)
G06T 17/05 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 29/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089549 Cao et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Yongqiang Cao (Newton, Massachusetts);  Narayan Srinivasa (Portland, Oregon)
ABSTRACT Described is a system for estimating ego-motion of a moving camera for detection of independent moving objects in a scene. For consecutive frames in a video captured by a moving camera, a first ego-translation estimate is determined between the consecutive frames from a first local minimum. From a second local minimum, a second ego-translation estimate is determined. If the first ego-translation estimate is equivalent to the second ego-translation estimate, the second ego-translation estimate is output as the optimal solution. Otherwise, a cost function is minimized to determine an optimal translation until the first ego-translation estimate is equivalent to the second ego-translation estimate, and an optimal solution is output. Ego-motion of the camera is estimated using the optimal solution, and independent moving objects are detected in the scene.
FILED Tuesday, May 02, 2017
APPL NO 15/584986
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 17/11 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/48 (20130101)
G06K 9/209 (20130101)
G06K 9/3241 (20130101) Original (OR) Class
G06K 2009/484 (20130101)

Image Data Processing or Generation, in General
G06T 7/215 (20170101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089977 Ganapathy et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Sriram Ganapathy (Hartford, Connecticut);  Mohamed K. Omar (Chappaqua, New York);  Robert Ward (Westchester, New York)
ABSTRACT Exemplary embodiments of the present invention provide a method of system combination in an audio analytics application including providing a plurality of language identification systems in which each of the language identification systems includes a plurality of probabilities. Each probability is associated with the system's ability to detect a particular language. The method of system combination in the audio analytics application includes receiving data at the language identification systems. The received data is different from data used to train the language identification systems. A confidence measure is determined for each of the language identification systems. The confidence measure identifies which language its system predicts for the received data and combining the language identification systems according to the confidence measures.
FILED Tuesday, July 07, 2015
APPL NO 14/793089
ART UNIT 2675 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Electric Digital Data Processing
G06F 17/275 (20130101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 15/02 (20130101)
G10L 15/005 (20130101) Original (OR) Class
G10L 15/18 (20130101)
G10L 15/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090043 Frank
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) David J. Frank (Yorktown Heights, New York)
ABSTRACT A quantum mechanical radio frequency (RF) signaling system includes a transmission line that receives and conducts an RF pulse signal operating at a radio frequency, a first qubit having a quantum mechanical state that is a linear combination of at least two quantum mechanical eigenstates, and a first network of reactive electrical components having an input that is coupled to the transmission line for receiving the RF pulse signal and an output that is coupled to the first qubit. The first network of reactive electrical components attenuates the amplitude of the RF pulse signal and produces a first attenuated RF pulse signal that is applied to the first qubit. The first attenuated RF pulse signal operates at the radio frequency and has a first attenuated amplitude that causes a predefined change in the linear combination of at least two quantum mechanical eigenstates within the first qubit.
FILED Wednesday, November 08, 2017
APPL NO 15/806432
ART UNIT 2631 — Digital Communications
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 99/002 (20130101)

Static Stores
G11C 11/44 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090226 Chainer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Timothy J. Chainer (Putnam Valley, New York);  Pritish R. Parida (Stamford, Connecticut);  Fanghao Yang (Somerset, New Jersey)
ABSTRACT A method of forming metallic pillars between a fluid inlet and outlet for two-phase fluid cooling. The method may include; forming an arrangement of metallic pillars between two structures, the metallic pillars are electrically connected to metallic connecting lines that run through each of the two structures, the arrangement of metallic pillars located between a fluid inlet and a fluid channel, the fluid channel having channel walls running between arrangements of the metallic pillars and a fluid outlet, whereby a fluid passes through the arrangement of metallic pillars to flow into the fluid channel.
FILED Tuesday, October 31, 2017
APPL NO 15/798521
ART UNIT 2899 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/4882 (20130101)
H01L 23/02 (20130101)
H01L 23/427 (20130101)
H01L 23/473 (20130101) Original (OR) Class
H01L 23/3675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090394 Hagleitner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
APPLICANT(S) Cree, Inc. (Durham, North Carolina)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Helmut Hagleitner (Zebulon, North Carolina);  Jason Gurganus (Raleigh, North Carolina)
ABSTRACT Embodiments of an ohmic contact structure for a Group III nitride semiconductor device and methods of fabrication thereof are disclosed. In general, the ohmic contact structure has a root-mean-squared (RMS) surface roughness of less than 10 nanometers, and more preferably less than or equal to 7.5 nanometers, and more preferably less than or equal to 5 nanometers, and more preferably less than or equal to 2 nanometers, and even more preferably less than or equal to 1.5 nanometers.
FILED Monday, November 28, 2016
APPL NO 15/361682
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/28575 (20130101)
H01L 29/452 (20130101) Original (OR) Class
H01L 29/2003 (20130101)
H01L 29/7787 (20130101)
H01L 29/66462 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090426 Wichman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts);  Adam R. Wichman (Dover, Massachusetts);  Enrico Bellotti (Watertown, Massachusetts);  Benjamin James Pinkie (Cambridge, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Adam R. Wichman (Dover, Massachusetts);  Enrico Bellotti (Watertown, Massachusetts);  Benjamin James Pinkie (Cambridge, Massachusetts)
ABSTRACT A photosensor device for reducing dark current is disclosed. The photosensor device includes a photon absorbing layer and two or more photosensor diffusions in said absorbing layer. The photosensor diffusions in the absorbing layer have edges of their diffusions separated in said absorbing layer by less than two minority carrier diffusion lengths. The photosensor device also includes in one embodiment one or more diffusion control junction diffusions in the absorbing layer and in proximity to the photosensor diffusions. In another embodiment the photosensor diffusions are selectively biased to operate as photosensor diodes or as diffusion impediments.
FILED Tuesday, May 05, 2015
APPL NO 15/308948
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1446 (20130101)
H01L 31/184 (20130101)
H01L 31/1013 (20130101)
H01L 31/02005 (20130101)
H01L 31/02966 (20130101)
H01L 31/03529 (20130101) Original (OR) Class
H01L 31/022408 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090557 Trevey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) James Trevey (Santa Monica, California);  Se-hee Lee (Louisville, Colorado);  Jae-Ha Woo (Boulder, Colorado)
ABSTRACT An electrochemical cell including a multi-layer solid-state electrolyte, a battery including the cell, and a method of forming the battery and cell are disclosed. The electrolyte includes a first layer that is compatible with the anode of the cell and a second layer that is compatible with the cathode of the cell. The cell exhibits improved performance compared to cells including a single-layer electrolyte.
FILED Wednesday, March 09, 2016
APPL NO 15/065706
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/021 (20130101)
H01M 2/024 (20130101)
H01M 2/26 (20130101)
H01M 2/30 (20130101)
H01M 4/043 (20130101)
H01M 4/131 (20130101)
H01M 4/134 (20130101)
H01M 4/382 (20130101)
H01M 4/386 (20130101)
H01M 4/0407 (20130101)
H01M 4/525 (20130101)
H01M 4/625 (20130101)
H01M 4/628 (20130101)
H01M 4/1391 (20130101)
H01M 10/0525 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 10/0585 (20130101)
H01M 2004/021 (20130101)
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)
H01M 2300/0094 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49115 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090603 Behdad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) Nader Behdad (Madison, Wisconsin);  Meng Li (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Nader Behdad (Madison, Wisconsin);  Meng Li (Madison, Wisconsin)
ABSTRACT A lens is provided. The lens includes a first two-dimensional (2-D) grid of capacitive patches and a first sheet layer. The first sheet layer includes a dielectric sheet and a second 2-D grid of capacitive patches. The dielectric sheet has a front surface and a back surface. The first 2-D grid of capacitive patches is mounted directly on the back surface of the dielectric sheet, and the second 2-D grid of capacitive patches is mounted directly on the front surface of the dielectric sheet. The first 2-D grid of capacitive patches is aligned with the second 2-D grid of capacitive patches to form a time delay circuit at each grid position of the aligned 2-D grids.
FILED Wednesday, May 30, 2012
APPL NO 13/483381
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 15/04 (20130101)
H01Q 15/0026 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090634 Manzur
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Tariq Manzur (Lincoln, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Tariq Manzur (Lincoln, Rhode Island)
ABSTRACT A laser communication apparatus is provided for sending and receiving messages. A processor encodes user messages for a modulator. The modulator provides control signals related to the encoded message to a plurality of seed lasers. Each seed laser can provide light at a different wavelength. Amplifiers are joined to amplify light from the seed lasers. Amplified light is multiplexed together. Multiplexed light is transmitted by a collimating lens along a target vector. A portion of the light can be monitored by a first detector. A telescope receives light from the target vector and provides focused light to a second detector. The second detector provides a signal responsive to the received light to the processor. The processor decodes this signal to provide the received message.
FILED Thursday, November 30, 2017
APPL NO 15/826836
ART UNIT 2636 — Optical Communications
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0085 (20130101)
H01S 3/1302 (20130101)
H01S 3/1305 (20130101)
H01S 3/2391 (20130101) Original (OR) Class
H01S 3/06754 (20130101)

Transmission
H04B 10/11 (20130101)
H04B 10/66 (20130101)
H04B 10/505 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090645 Bovington et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Oracle International Corporation (Redwood Shores, California)
ASSIGNEE(S) Oracle International Corporation (Redwood Shores, California)
INVENTOR(S) Jock T. Bovington (La Jolla, California);  Xuezhe Zheng (San Diego, California);  Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT An integrated laser that provides multiple outputs includes a reflective silicon optical amplifier (RSOA) having a reflective end with a reflective coating and an interface end. It also includes an optical waveguide optically coupled to the RSOA. A distributed-Bragg-reflector (DBR) ring resonator is also optically coupled to the optical waveguide, wherein the DBR ring resonator partially reflects a wavelength of the optical signal from the optical waveguide, thereby causing balanced light to flow in clockwise and counter-clockwise directions inside the DBR ring resonator. The integrated laser additionally includes an output waveguide having 2*N ends that function as two outputs, wherein the output waveguide is optically coupled to the DBR ring resonator, which causes balanced light to flow in two directions in the output waveguide, thereby causing the 2*N outputs to provide balanced power.
FILED Thursday, June 23, 2016
APPL NO 15/190994
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/1228 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/50 (20130101) Original (OR) Class
H01S 5/125 (20130101)
H01S 5/1014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090910 Mo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Intelligent Fusion Technology, Inc. (Germantown, Maryland)
ASSIGNEE(S) INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
INVENTOR(S) Zijian Mo (Germantown, Maryland);  Zhonghai Wang (Germantown, Maryland);  Gang Wang (Germantown, Maryland);  Genshe Chen (Germantown, Maryland);  Tien Nguyen (Germantown, Maryland);  Khanh Pham (Germantown, Maryland)
ABSTRACT In accordance with various embodiments, a method for uplink multiple accessing based on code division multiple access (CDMA) technology and a related system are provided. The method comprises: designing a practical uplink spreading waveform for a code division multiple access (CDMA) based SCN by leveraging a plurality of pseudorandom sequences and investigating a channel coding block and a modulation block for the CDMA based SCN; determining an uplink frequency sub-band division for the CDMA based SCN to optimize a tradeoff between a performance and an implementation cost of CDMA based SCN; and specifying a configuration of a control system of the CDMA based SCN.
FILED Tuesday, December 13, 2016
APPL NO 15/377892
ART UNIT 2414 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 7/216 (20130101)
H04B 7/18513 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091092 Soomro
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) GOVERMENT OF THE UNITED STATES AS REPRESENTED BY TE SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Amjad Soomro (Whitesboro, New York)
ABSTRACT This invention provides systems and methods to make communication networks more resilient, stealthier and robust. This invention discloses systems and methods wherein either a communications user equipment (UE) with multiple types of wireless links, potentially operating in different frequency bands, or an apparatus which performs communications routing functions, changes the communications routing in pseudo-random manner.
FILED Friday, February 03, 2017
APPL NO 15/423686
ART UNIT 2469 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/02 (20130101) Original (OR) Class
H04L 45/22 (20130101)
H04L 45/54 (20130101)
H04L 63/162 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091094 Garcia-Luna-Aceves et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jose Garcia-Luna-Aceves (Santa Cruz, California);  Qian Li (Santa Cruz, California)
ABSTRACT A distance-vector based routing protocol that integrates with adaptive publish-subscribe mechanisms by establishing routes to well-known controllers using distance-vector signaling.
FILED Thursday, October 16, 2014
APPL NO 15/030366
ART UNIT 2468 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/02 (20130101)
H04L 45/18 (20130101)
H04L 45/026 (20130101)
H04L 45/44 (20130101)
H04L 45/54 (20130101)
H04L 45/122 (20130101) Original (OR) Class
H04L 45/7453 (20130101)

Wireless Communication Networks
H04W 40/02 (20130101)
H04W 40/24 (20130101)
H04W 40/246 (20130101)
H04W 84/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091181 Cheng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Pau-Chen Cheng (Yorktown Heights, New York);  Lawrence Koved (Pleasantville, New York);  Kapil K. Singh (Cary, North Carolina);  Calvin B. Swart (Poughkeepsie, New York);  Sharon M. Trewin (Croton-on-Hudson, New York)
ABSTRACT Dynamic risk communication associated with a computer device may include automatically detecting one or more security risk factors for the computer device based on current context information associated with the computer device. Whether an attempt is being made via the computer device to manipulate the one or more risk factors in an attempt to reduce a security level of a computer-implemented authentication procedure may be determined. Responsive to determining that the attempt is being made to manipulate the one or more risk factors, a new challenge for additional identification may be communicated for presentation on a user interface device of the computer device while suppressing one or more security risk factors from being presented on the user interface device. Responsive to determining that an attempt is not being made to manipulate the one or more risk factors, the new challenge and one or more security risk factors may be communicated.
FILED Friday, June 09, 2017
APPL NO 15/618283
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/31 (20130101)
G06F 21/577 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/08 (20130101) Original (OR) Class
H04L 63/10 (20130101)
H04L 63/1425 (20130101)
H04L 63/1433 (20130101)

Wireless Communication Networks
H04W 12/06 (20130101)
H04W 12/08 (20130101)
H04W 12/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091218 Holland et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Gavin D. Holland (Newbury Park, California);  Michael D. Howard (Westlake Village, California);  Chong Ding (Riverside, California)
ABSTRACT Described is a system for detecting attacks of misinformation on communication networks. Network controllability metrics on a graphical representation of a communication network are computed. Changes in the network controllability metrics are detected, and attack of misinformation on the communication network are detected based on the detected changes in the network controllability metrics.
FILED Friday, March 18, 2016
APPL NO 15/075058
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 7/005 (20130101)
G06N 99/005 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1416 (20130101) Original (OR) Class
H04L 63/1425 (20130101)
H04L 63/1441 (20130101)

Wireless Communication Networks
H04W 12/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091498 Higdon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James Higdon (Ridgecrest, California);  Jason Witzel (Ridgecrest, California)
ABSTRACT A video timing test equipment for measuring light integration time of a camera. The video timing test equipment may comprise: a control unit and shutter timing test unit. The control unit may generate input timing signals adjustable by a user. The shutter timing test unit may comprise light emitting diodes (LEDs), infrared light emitting diodes (IR LEDs), and an output controller. The output controller may regulate the illumination of the LEDs and IR LEDs based on the input timing signals. The shutter timing test unit may also comprise a UTC time display, edge time display, and pulse width display. The UTC time display may depict a UTC time as to when light integration begins or ends. The edge time display may depict an offset time associated with the start or end of light integration. The pulse width display may depict the duration of light integration.
FILED Monday, November 27, 2017
APPL NO 15/822984
ART UNIT 2422 — Cable and Television
CURRENT CPC
Pictorial Communication, e.g Television
H04N 17/002 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091664 Wieneke et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Garry V Wieneke (Montgomery, Indiana);  Gerry F Miller (Bedford, Indiana);  Ameer Beitvashahi (Bloomington, Indiana)
ABSTRACT Exemplary apparatuses and methods are provided associated with an unobtrusive router/relay system (URRS) configured to communicate with a plurality of radio frequency (RF) systems including a first radio frequency (RF) system (e.g. a cell phone, RF system carried or used by an individual or team, etc.), other URRS systems (which each include a second RF receiver/transmitter), and an RF communication's hub (e.g. cell tower, tethered UAV, control center, etc.). Locations are identified for a specific location or number of locations along a transit path where the RF communication's hub lacks transmit/receive coverage with the first RF system. URRS are positioned in the locations or transit path lacking RF communication hub transmit/receive coverage. The exemplary URRS are configured to route/relay the first RF system's signals to the RF communications' hub directly or through one or more other URRS systems. URRS are designed to blend with their surroundings.
FILED Saturday, September 30, 2017
APPL NO 15/721869
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/02 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 20/32 (20141201)

Transmission
H04B 7/2606 (20130101)
H04B 7/18504 (20130101)

Wireless Communication Networks
H04W 16/26 (20130101) Original (OR) Class
H04W 52/0235 (20130101)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 60/50 (20130101)

Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use
Y02D 70/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091785 Hu et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Board of Trustees of The University of Alabama (Tuscaloosa, Alabama)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (Tuscaloosa, Alabama)
INVENTOR(S) Fei Hu (Tuscaloosa, Alabama);  Yeqing Wu (Tuscaloosa, Alabama)
ABSTRACT Systems and methods for managing spectrum handoff with multimedia transmissions over cognitive radio networks are disclosed. The methods may include, for example, determining when a primary user is inactive on the one or more frequencies. The methods may also include assigning a secondary user to the one or more frequencies while the primary user is inactive and detecting return by the primary user to the one or more frequencies. The secondary user may, in one embodiment, be interrupted and one or more second frequencies that are inactive may be identified. Further, the secondary user may transition to the one or more second frequencies to resume transmission or reception.
FILED Thursday, June 11, 2015
APPL NO 14/736412
ART UNIT 2412 — Multiplex and VoIP
CURRENT CPC
Wireless Communication Networks
H04W 16/14 (20130101)
H04W 36/06 (20130101)
H04W 72/10 (20130101)
H04W 72/0453 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091798 Learned et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Rachel E. Learned (Waltham, Massachusetts);  Nicholas J. Kaminski (Blacksburg, Virginia)
ABSTRACT An SUOC radio employs: (1) Spectrum sensing and parameter estimation methods to characterize potential FUOCs; (2) A rate pair prediction tool to guide it's choice of FUOC to target along with the appropriate rate pair (SUOC and FUOC achievable rates); (3) Machine learning methods to automatically and on the fly advantage experience/history; (4) A decision maker with multiple possible procedures that govern steps of interaction; (5) Multiuser detection receiver to deal with the interference once information-bearing transmission has commenced by the SUOC radios. (6) a radio capable of full transmit-processing chain to accomplish modulation and full receive-processing chain to accomplish demodulation, as well as other radio functions necessary for successful wireless communications such as medium access control, networking and other functions.
FILED Friday, June 09, 2017
APPL NO 15/618848
ART UNIT 2464 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/00 (20130101)
H04L 27/0006 (20130101)

Wireless Communication Networks
H04W 16/14 (20130101)
H04W 52/243 (20130101)
H04W 52/267 (20130101)
H04W 52/343 (20130101)
H04W 52/367 (20130101)
H04W 72/082 (20130101) Original (OR) Class
H04W 72/0453 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 10086331 Brennecke et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) University of Notre Dame du Lac (Notre Dame, Indiana)
ASSIGNEE(S) University of Notre Dame du Lac (Notre Dame, Indiana)
INVENTOR(S) Joan F. Brennecke (Notre Dame, Indiana);  Edward J. Maginn (Notre Dame, Indiana);  William F. Schneider (Notre Dame, Indiana)
ABSTRACT Disclosed herein are methods for CO2 capture that use phase change ionic liquids (PCILs) to remove the CO2 from flue gas or other gas streams containing CO2. PCILs have high CO2 uptake and form a liquid PCIL-CO2 complex when they react with C( )2. When the liquid PCIL-CO2 complex is heated to regenerate the solid PCIL material by removing the carbon dioxide, part of the heat needed to release the CO2 can be supplied by the heat of fusion of the PCIL as it solidifies. Utilization of the heat of fusion of the PCIL to assist in its own regeneration can substantially reduce the parasitic energy loss associated with post-combustion CO2 capture.
FILED Wednesday, November 05, 2014
APPL NO 15/034464
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/62 (20130101)
B01D 53/83 (20130101) Original (OR) Class
B01D 53/1425 (20130101)
B01D 53/1475 (20130101)
B01D 53/1493 (20130101)
B01D 2251/80 (20130101)
B01D 2252/30 (20130101)
B01D 2257/504 (20130101)
B01D 2258/0283 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/2342 (20180101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/04 (20130101)
Y02C 10/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086339 Parnas et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
ASSIGNEE(S) THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S) Richard Steven Parnas (Ashford, Connecticut);  Alexandru Asandei (Vernon, Connecticut);  Baishali Kanjilal (West Haven, Connecticut);  Iman Noshadi (Cambridge, Massachusetts)
ABSTRACT A polymer having a contact angle with water that is greater than or equal to 90° and a contact angle with 1,3-propane diol that is less than 90°. A pervaporation membrane comprising the polymer and a process for purifying a fermentation broth using a pervaporation membrane comprising the polymer is also described.
FILED Thursday, March 10, 2016
APPL NO 15/066697
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 61/362 (20130101)
B01D 69/02 (20130101)
B01D 71/40 (20130101)
B01D 71/48 (20130101)
B01D 71/60 (20130101)
B01D 71/82 (20130101) Original (OR) Class
B01D 2323/04 (20130101)
B01D 2325/38 (20130101)

Acyclic or Carbocyclic Compounds
C07C 29/76 (20130101)
C07C 29/76 (20130101)
C07C 31/205 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 26/06 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 77/16 (20130101)
C08G 77/388 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/57 (20130101)
C08K 5/5415 (20130101)

Compositions of Macromolecular Compounds
C08L 83/00 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 183/08 (20130101)
C09D 183/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086431 Bagge-Hansen et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) Lawrence Livermoe National Security, LLC (Livermore, California);  National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Michael Bagge-Hansen (San Leandro, California);  Patrick G. Campbell (Oakland, California);  Jeffrey D. Colvin (Pleasanton, California);  Sergei Kucheyev (Oakland, California);  Thomas E. Felter (Livermore, California)
ABSTRACT Disclosed here is a method for making a nanoporous material, comprising aerosolizing a solution comprising at least one metal salt and at least one solvent to obtain an aerosol, freezing the aerosol to obtain a frozen aerosol, and drying the frozen aerosol to obtain a nanoporous metal compound material. Further, the nanoporous metal compound material can be reduced to obtain a nanoporous metal material.
FILED Tuesday, June 16, 2015
APPL NO 14/741334
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0018 (20130101) Original (OR) Class
B22F 1/0022 (20130101)
B22F 9/026 (20130101)
B22F 9/082 (20130101)
B22F 2009/084 (20130101)
B22F 2009/0824 (20130101)
B22F 2009/0832 (20130101)
B22F 2009/0844 (20130101)
B22F 2009/0864 (20130101)
B22F 2201/013 (20130101)
B22F 2201/20 (20130101)
B22F 2202/03 (20130101)
B22F 2301/10 (20130101)
B22F 2301/255 (20130101)
B22F 2304/05 (20130101)
B22F 2304/10 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 40/00 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087118 Weihs et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Timothy P. Weihs (Baltimore, Maryland);  Alex H. Kinsey (Baltimore, Maryland);  Kyle A. Slusarski (Joppa, Maryland);  Karsten Woll (Karlsruhe, Germany);  David Gibbins (Towson, Maryland)
ABSTRACT A reactive composite foil, including metallic fuel particles, oxidizer particles, and a diluent, which, when ignited, produces a self-propagating thermite reaction to produce a molten metal.
FILED Monday, November 30, 2015
APPL NO 14/954508
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 1/0006 (20130101)
B23K 35/0222 (20130101)
B23K 35/0238 (20130101)
B23K 35/0244 (20130101)
B23K 35/286 (20130101)
B23K 35/325 (20130101)
B23K 35/3033 (20130101)

Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0033 (20130101)
C06B 33/00 (20130101) Original (OR) Class
C06B 45/00 (20130101)
C06B 45/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087137 Yamamoto et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The University of Toledo (Toledo, Ohio)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio)
INVENTOR(S) Kana Yamamoto (Toledo, Ohio);  Sridhar Viamajala (Toledo, Ohio);  Sasidhar Varanasi (Toledo, Ohio);  Kim Nguyen (Toledo, Ohio);  Godwin Abel (Toledo, Ohio);  Ajith Yapa Mudiyanselage (Toledo, Ohio)
ABSTRACT A concise method of producing nylon 11, 12, or 13 precursors from oleic acid or an ester of oleic acid is described. The method involves cross-metathesis reactions as the key C—C bond formation step. Subsequent steps are provided to convert the metathesis product to the corresponding nylon precursors. Also provided are the products of the method.
FILED Monday, June 22, 2015
APPL NO 15/320802
ART UNIT 1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 67/303 (20130101)
C07C 67/303 (20130101)
C07C 67/333 (20130101)
C07C 67/333 (20130101)
C07C 69/675 (20130101)
C07C 69/732 (20130101)
C07C 227/04 (20130101) Original (OR) Class
C07C 227/04 (20130101)
C07C 229/08 (20130101)
C07C 229/08 (20130101)
C07C 253/30 (20130101)
C07C 253/30 (20130101)
C07C 255/23 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087205 Yaghi et al.
FUNDED BY
Department of Defense (DOD)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Omar M. Yaghi (Berkeley, California);  Mitsuharu Suzuki (Albany, California);  Hexiang Deng (Berkeley, California);  Lisa Wang (Los Angeles, California)
ABSTRACT The disclosure provides for metal organic frameworks (MOFs) which comprise a plurality of SBUs comprising different metals or metal ions and/or a plurality of organic linking moieties comprising different functional groups.
FILED Friday, March 27, 2015
APPL NO 15/128225
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/204 (20130101)
B01D 2257/108 (20130101)
B01D 2257/504 (20130101)
B01D 2257/7025 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101)
B01J 31/1691 (20130101)
B01J 2531/22 (20130101)
B01J 2531/23 (20130101)
B01J 2531/24 (20130101)
B01J 2531/25 (20130101)
B01J 2531/26 (20130101)
B01J 2531/27 (20130101)
B01J 2531/72 (20130101)
B01J 2531/842 (20130101)
B01J 2531/845 (20130101)
B01J 2531/847 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 3/02 (20130101)
C07F 19/005 (20130101) Original (OR) Class

Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 11/005 (20130101)
F17C 11/007 (20130101)
F17C 2221/012 (20130101)
F17C 2221/013 (20130101)
F17C 2221/033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087425 Neidle et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Ellen Lee Neidle (Dacula, Georgia);  Christopher W. Johnson (Denver, Colorado);  Gregg Tyler Beckham (Golden, Colorado);  Jeffrey G. Linger (Denver, Colorado);  Mark Andrew Eiteman (Athens, Georgia);  Melissa Tumen-Velasquez (Athens, Georgia);  Alaa Ashraf Mahmoud Ahmed (Athens, Georgia)
ABSTRACT Disclosed herein are enzymes useful for the dealkylation of aromatic substrates, including the conversion of guaiacol or guaethol to catechol. Methods of converting aromatic substrates found in lignin-based feedstocks such as pyrolysis oil into products such as catechol are also disclosed. Also presented herein are methods for rapidly evolving and optimizing genetic regions.
FILED Tuesday, July 25, 2017
APPL NO 15/658789
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0069 (20130101) Original (OR) Class
C12N 9/0071 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/22 (20130101)
C12P 7/44 (20130101)

Enzymes
C12Y 113/11001 (20130101)
C12Y 114/14001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087478 Quinlan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Novozymes, Inc. (Davis, California)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Jason Quinlan (Woodland, California);  Feng Xu (Davis, California);  Matthew Sweeney (Sacramento, California)
ABSTRACT The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a nitrogen-containing compound. The present invention also relates to methods of using the compositions.
FILED Thursday, April 21, 2016
APPL NO 15/134757
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/96 (20130101)
C12N 9/2437 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 5/002 (20130101)
C12P 5/02 (20130101)
C12P 5/026 (20130101)
C12P 7/10 (20130101)
C12P 7/26 (20130101)
C12P 7/28 (20130101)
C12P 7/40 (20130101)
C12P 13/04 (20130101)
C12P 19/02 (20130101)
C12P 19/12 (20130101)
C12P 19/14 (20130101) Original (OR) Class
C12P 2201/00 (20130101)
C12P 2203/00 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087531 Sabolsky et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S) West Virginia University (Morgantown, West Virginia)
INVENTOR(S) Edward M. Sabolsky (Morgantown, West Virginia);  Ozcan Ozmen (Morgantown, West Virginia);  John W. Zondlo (Albright, West Virginia)
ABSTRACT A process for incorporating a nanocatalyst on the surface of and within the pores of an electrode comprising subjecting an electrode to a singular template impregnation to form a treated electrode having a bio-template layer; and then subjecting the treated electrode to a singular nano-catalyst impregnation for tethering the nano-catalyst to the treated electrode; and then removing the bio-template layer by performing thermolysis upon the treated electrode for forming a nano-catalyst bonded on the surface and within the pores of the electrode. A modified electrode or product made by this process is provided.
FILED Wednesday, December 09, 2015
APPL NO 14/963564
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/04 (20130101) Original (OR) Class
C25B 11/035 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8846 (20130101)
H01M 4/8882 (20130101)
H01M 8/1246 (20130101)
H01M 2008/1293 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/366 (20130101)
Y02E 60/525 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/56 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087535 Friedman et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Daniel Joseph Friedman (Lakewood, Colorado);  Todd Gregory Deutsch (Westminster, Colorado);  John A. Turner (Broomfield, Colorado);  Henning Doscher (Bad Bederkesa, Germany);  James Luke Young (Boulder, Colorado);  Myles Steiner (Denver, Colorado);  Ryan Matthew France (Golden, Colorado)
ABSTRACT The present disclosure relates to photoelectrochemical devices and systems for capturing the energy of electromagnetic radiation and utilizing the captured energy for electrolysis to produce hydrogen gas and oxygen gas.
FILED Wednesday, March 23, 2016
APPL NO 15/078206
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/003 (20130101)
C25B 9/08 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/368 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/134 (20151101)
Y02P 20/135 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087538 Gordon
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) FIELD UPGRADING LIMITED (Calgary, Canada)
ASSIGNEE(S) FIELD UPGRADING LIMITED (Calgary, Canada)
INVENTOR(S) John Howard Gordon (Salt Lake City, Utah)
ABSTRACT Alkali metals and sulfur may be recovered from alkali monosulfide and polysulfides in an electrolytic process that utilizes an electrolytic cell having an alkali ion conductive membrane. An anolyte includes an alkali monosulfide, an alkali polysulfide, or a mixture thereof and a solvent that dissolves elemental sulfur. A catholyte includes molten alkali metal. Applying an electric current oxidizes sulfide and polysulfide in the anolyte compartment, causes alkali metal ions to pass through the alkali ion conductive membrane to the catholyte compartment, and reduces the alkali metal ions in the catholyte compartment. Liquid sulfur separates from the anolyte and may be recovered. The electrolytic cell is operated at a temperature where the formed alkali metal and sulfur are molten.
FILED Thursday, September 29, 2016
APPL NO 15/279926
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 17/22 (20130101)
C01B 17/34 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 32/02 (20130101)
C10G 2300/202 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/00 (20130101)

Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor
C25C 1/02 (20130101) Original (OR) Class
C25C 3/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087539 Powell, IV et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
APPLICANT(S) Infinium, Inc. (Natick, Massachusetts)
ASSIGNEE(S) Infinium, Inc. (Natick, Massachusetts)
INVENTOR(S) Adam Clayton Powell, IV (Newton, Massachusetts);  John Strauss (Rindge, New Hampshire);  Robert Steve Tucker (New York, New York);  Jason Brodie Voellinger (Allston, Massachusetts)
ABSTRACT Methods separates a gas comprising providing a first electrode in ion-conducting contact with an electrolyte, providing a second electrode in ion-conducting contact with the electrolyte, wherein the second electrode comprises a liquid metal, providing a displacing material comprising a first surface in contact with the second electrode and a second surface exposed to an environment outside the second electrode, wherein said material permits flow of gas and impedes flow of liquid metal, and establishing a potential between the first and second electrodes, whereby gas flows toward the liquid metal. Other aspects include methods and apparatuses comprising electrodes, electrolytes and displacing materials.
FILED Thursday, June 12, 2014
APPL NO 14/897724
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/02 (20130101)
C25B 9/14 (20130101)

Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor
C25C 3/00 (20130101)
C25C 3/02 (20130101)
C25C 3/04 (20130101)
C25C 7/005 (20130101) Original (OR) Class
C25C 7/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087547 Chen et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Kevin Chen (Berkeley, California);  Rehan Kapadia (Los Angeles, California);  Ali Javey (Lafayette, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Kevin Chen (Berkeley, California);  Rehan Kapadia (Los Angeles, California);  Ali Javey (Lafayette, California)
ABSTRACT This disclosure provides systems, methods, and apparatus related to the growth of single crystal III-V semiconductors on amorphous substrates. In one aspect, a shape of a semiconductor structure to be formed on an amorphous substrate is defined in a resist disposed on the amorphous substrate. A boron group element is deposited over the amorphous substrate. A ceramic material is deposited on the boron group element. The resist is removed from the amorphous substrate. The ceramic material is deposited to cover the boron group element. The amorphous substrate and materials deposited thereon are heated in the presence of a gas including a nitrogen group element to grow a single crystal semiconductor structure comprising the boron group element and the nitrogen group element.
FILED Thursday, November 17, 2016
APPL NO 15/354063
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 1/02 (20130101)
C30B 1/10 (20130101) Original (OR) Class
C30B 25/02 (20130101)
C30B 25/04 (20130101)
C30B 29/40 (20130101)
C30B 29/403 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02422 (20130101)
H01L 21/02428 (20130101)
H01L 21/02488 (20130101)
H01L 21/02543 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087776 Lacy et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Benjamin Paul Lacy (Greer, South Carolina);  Srikanth Chandrudu Kottilingam (Greenville, South Carolina);  David Edward Schick (Greenville, South Carolina)
ABSTRACT A cooling article and method of forming a cooling article are provided. The cooling article includes a body portion separating an inner region and an outer region, an aperture in the body portion, the aperture fluidly connecting the inner region and the outer region, and a reinforcing feature extending at least partially along the body portion, the reinforcing feature being oriented with respect to a build direction. The method includes forming a body portion defining an inner region and an outer region, forming at least one reinforcing feature concurrently with the forming of the body portion, the at least one reinforcing feature extending at least partially along the body portion, and forming an aperture in the body portion, the aperture fluidly connecting the inner region to the outer region. The forming the body portion, forming the aperture, and forming the at least one reinforcing feature comprises additive manufacturing.
FILED Tuesday, September 08, 2015
APPL NO 14/847445
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 5/04 (20130101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/342 (20151001)
B23K 26/354 (20151001)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/188 (20130101)
F01D 5/189 (20130101)
F01D 25/12 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2230/31 (20130101)
F05D 2260/201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087844 Hughes et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Michael John Hughes (Pittsburgh, Pennsylvania);  Stanley Kevin Widener (Greenville, South Carolina);  Jonathan Dwight Berry (Simpsonville, South Carolina)
ABSTRACT A bundled tube fuel nozzle assembly includes a fuel injector and a tube bundle comprising a plurality of tubes that provide for fluid communication through a forward plate, a fuel plenum and an aft plate of the bundled tube fuel nozzle assembly. Each tube includes an inlet defined at an upstream end of the tube and an outlet defined at a downstream end of the tube. The fuel injector is disposed upstream from the inlets of each of the tubes. The upstream end of each tube is noncircular and includes at least one side portion that abuts a complementary upstream end side portion of an immediately adjacent tube of the plurality of tubes. The downstream end of each tube may be circular and is spaced apart from the downstream ends of immediately adjacent tubes of the plurality of tubes.
FILED Wednesday, November 18, 2015
APPL NO 14/944298
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/22 (20130101)
F02C 7/222 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/35 (20130101)

Burners
F23D 14/62 (20130101)
F23D 14/64 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/04 (20130101)
F23R 3/10 (20130101)
F23R 3/12 (20130101)
F23R 3/14 (20130101)
F23R 3/28 (20130101)
F23R 3/32 (20130101)
F23R 3/36 (20130101)
F23R 3/045 (20130101)
F23R 3/286 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087910 Mandre et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Brown University (Providence, Rhode Island)
ASSIGNEE(S) BROWN UNIVERSITY (Providence, Rhode Island)
INVENTOR(S) Shreyas Mandre (Providence, Rhode Island);  Kenneth Breuer (Newton, Massachusetts);  Benjamin Strom (Providence, Rhode Island);  Michael Miller (Providence, Rhode Island);  Jennifer Franck (Providence, Rhode Island);  Daegyoum Kim (Providence, Rhode Island)
ABSTRACT The present invention provides a system for engaging a fluid flow. The system comprising one or more foil members operationally connected to a feedback control loop system. In one embodiment, the foil member is a hydrofoil member or an airfoil member. The foil members are configured for one or more degrees of freedom of oscillatory movement within the fluid flow. The feedback control loop system comprises a sensor system, actuator system, and a controller system. The feedback control loop system configured for actuating the foil members and thereby optimizing the operation of the foil members to attain one or more optimization objectives. In operation, the foil members are situated in the fluid flow and are manipulated to attain one or more optimization objectives.
FILED Tuesday, January 21, 2014
APPL NO 14/160337
ART UNIT 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Machines or Engines for Liquids
F03B 13/264 (20130101)
F03B 15/00 (20130101) Original (OR) Class
F03B 17/06 (20130101)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2260/70 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088101 Griffith et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Other Lab, LLC (San Francisco, California)
ASSIGNEE(S) OTHER LAB, LLC (San Francisco, California)
INVENTOR(S) Saul Griffith (San Francisco, California);  Tucker Gilman (San Francisco, California);  Peter S. Lynn (Oakland, California);  Kevin Simon (San Francisco, California)
ABSTRACT A high-pressure pressure vessel for storing natural gas comprises a plurality of first vessel regions of first diameters, a plurality of couplers, and a fiber layer. A three dimensional volume is filled using at least in part the plurality of first vessel regions. Each coupler of the plurality of couplers couples each pair of first vessel regions of the plurality of first vessel regions. Each coupler of the plurality of couplers comprises a second vessel region of a second diameter and two third vessel regions that transition diameters between the first diameter and the second diameter. The three dimensional volume is filled using at least in part the plurality of couplers. The first vessel regions and the couplers comprise a material with low permeability to natural gas. The fiber layer surrounds the plurality of first vessel regions and the plurality of couplers.
FILED Tuesday, February 04, 2014
APPL NO 14/172831
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 1/00 (20130101) Original (OR) Class
F17C 2201/056 (20130101)
F17C 2201/058 (20130101)
F17C 2201/0138 (20130101)
F17C 2203/066 (20130101)
F17C 2203/0619 (20130101)
F17C 2203/0663 (20130101)
F17C 2205/0111 (20130101)
F17C 2205/0332 (20130101)
F17C 2209/222 (20130101)
F17C 2209/2154 (20130101)
F17C 2221/033 (20130101)
F17C 2223/036 (20130101)
F17C 2223/0123 (20130101)
F17C 2260/017 (20130101)
F17C 2260/018 (20130101)
F17C 2270/0178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088491 Valdez et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Carlos A. Valdez (San Ramon, California);  Alexander K. Vu (Dublin, California)
ABSTRACT Provided herein are methods for sequestering an alkyne-presenting molecule in a sample and related sequestration reagents, compositions, methods and systems.
FILED Friday, March 07, 2014
APPL NO 14/201545
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 112/08 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
G01N 33/743 (20130101) Original (OR) Class
G01N 33/1826 (20130101)
G01N 33/5308 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088590 Sinha et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico);  Dipen N. Sinha (Los Alamos, New Mexico);  Anirban Chaudhuri (Los Alamos, New Mexico);  Cristian Pantea (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Dipen N. Sinha (Los Alamos, New Mexico);  Anirban Chaudhuri (Los Alamos, New Mexico);  Cristian Pantea (Los Alamos, New Mexico)
ABSTRACT Methods for real-time, continuous measurements of the composition and other properties of individual phases of petroleum, water and gas mixtures during the oil production process, without requiring test separators, test lines, with associated valving and instrumentation, are described. Embodiments of the present invention direct ultrasonic sound transmission through a flowing multiphase fluid in three frequency ranges: low frequencies, gas bubble resonance frequencies, and high frequencies, wherein certain sound propagation measurements, including sound speed, sound attenuation and sound scattering, are made in one or more of the three separate frequency regions, from which the multiphase composition and other properties are extracted without having to separate the multiphase fluid or the gas from the flowing stream.
FILED Friday, April 04, 2014
APPL NO 14/782090
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 49/087 (20130101)

Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/74 (20130101)
G01F 1/667 (20130101)
G01F 1/668 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/44 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088735 DeVore et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Peter Thomas Setsuda DeVore (Pleasant Hill, California);  Jason T. Chou (Walnut Creek, California)
ABSTRACT An Optical Information Transfer Enhancer System includes a first system for producing an information bearing first optical wave that is impressed with a first information having a first information strength wherein the first optical wave has a first shape. A second system produces a second optical wave. An information strength enhancer module receives the first and said second optical waves and impresses the first optical wave upon the second optical wave via cross-phase modulation (XPM) to produce an information-strength-enhanced second optical wave having a second information strength that is greater than the first information strength of the first optical wave. Following a center-wavelength changer by an Optical Information Transfer Enhancer System improves its performance.
FILED Tuesday, November 21, 2017
APPL NO 15/819948
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/10 (20130101)
G02B 27/283 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3511 (20130101) Original (OR) Class

Transmission
H04B 10/11 (20130101)
H04B 10/503 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089160 Robbins et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Kevin Robbins (Albuquerque, New Mexico);  Charles E. Brady (Albuquerque, New Mexico);  Tad A. Ashlock (Albuquerque, New Mexico)
ABSTRACT A system on chip (SoC) module is described herein, wherein the SoC modules comprise a processor subsystem and a hardware logic subsystem. The processor subsystem and hardware logic subsystem are in communication with one another, and transmit event messages between one another. The processor subsystem executes software actors, while the hardware logic subsystem includes hardware actors, the software actors and hardware actors conform to an event-driven architecture, such that the software actors receive and generate event messages and the hardware actors receive and generate event messages.
FILED Wednesday, August 30, 2017
APPL NO 15/690692
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/546 (20130101) Original (OR) Class
G06F 15/7871 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089181 Cher
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Chen-Yong Cher (Port Chester, New York)
ABSTRACT According to an aspect, a method for triggering creation of a checkpoint in a computer system includes executing a task in a processing node and determining whether it is time to read a monitor associated with a metric of the task. The monitor is read to determine a value of the metric based on determining that it is time to read the monitor. A threshold for triggering creation of the checkpoint is determined based on the metric. A monitoring block size is determined for the checkpoint. A checkpoint interval is determined based on the monitoring block size, a checkpoint bandwidth, and a failure rate of the computer system. Based on determining that the value of the metric has crossed the threshold and the checkpoint interval has elapsed, the checkpoint including state data of the task is created to enable restarting execution of the task upon a restart operation.
FILED Tuesday, June 28, 2016
APPL NO 15/194884
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/1438 (20130101) Original (OR) Class
G06F 11/3037 (20130101)
G06F 11/3409 (20130101)
G06F 2201/81 (20130101)
G06F 2201/85 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089845 Skorpik et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) James R. Skorpik (Kennewick, Washington);  Michael S. Hughes (Richland, Washington);  Eric G. Gonzalez (Richland, Washington)
ABSTRACT A system and method of detecting and analyzing a threat in a confined environment is disclosed. An audio board detects and analyzes audio signals. A RF board transmits the signals for emergency response. A battery provides power to the audio board and the RF board. The audio board includes a microcontroller with at least one band-pass filter for distinguishing between a threat and a non-threat event and for measuring or counting pulses if the event is a threat.
FILED Thursday, March 05, 2015
APPL NO 14/639647
ART UNIT 2686 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 13/1672 (20130101)
G08B 21/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090034 Belashchenko et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska);  THE JOHN HOPKINS UNIVERSITY (Baltimore, Maryland);  INTEL CORPORATION (Santa Clara, California)
INVENTOR(S) Kirill D. Belashchenko (Lincoln, Nebraska);  Oleg Tchernyshyov (Baltimore, Maryland);  Alexey Kovalev (Lincoln, Nebraska);  Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT A magnetoelectric memory cell with domain-wall-mediated switching is implemented using a split gate architecture. The split gate architecture allows a domain wall to be trapped within a magnetoelectric antiferromagnetic (MEAF) active layer. An extension of this architecture applies to multiple-gate linear arrays that can offer advantages in memory density, programmability, and logic functionality. Applying a small anisotropic in-plane shear strain to the MEAF can block domain wall precession to improve reliability and speed of switching.
FILED Wednesday, November 08, 2017
APPL NO 15/807369
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101) Original (OR) Class
G11C 11/1673 (20130101)
G11C 11/1675 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/228 (20130101)
H01L 43/08 (20130101)
H01L 43/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090425 Lewis et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Joint Center for Artificial Photosynthesis (JCAP)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Nathan S. Lewis (La Canada Flintridge, California);  Shu Hu (Pasadena, California)
ABSTRACT A photoelectrode, methods of making and using, including systems for water-splitting are provided. The photoelectrode can be a semiconducting material having a photocatalyst such as nickel or nickel-molybdenum coated on the material. The photoelectrode includes an elongated axially integrated wire having at least two different wire compositions.
FILED Wednesday, February 20, 2013
APPL NO 13/771617
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 13/0207 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/003 (20130101)
C25B 9/08 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/078 (20130101)
H01L 31/0687 (20130101)
H01L 31/1804 (20130101)
H01L 31/1892 (20130101)
H01L 31/03529 (20130101)
H01L 31/035236 (20130101) Original (OR) Class
H01L 31/035281 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/544 (20130101)
Y02E 10/547 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/521 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090466 Chan et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ching-Kit Chan (Los Angeles, California);  Patrick A. Lee (Brookline, Massachusetts);  Netanel Lindner (Aviel, Israel);  Gil Refael (Pasadena, California);  Qiong Ma (Cambridge, Massachusetts);  Suyang Xu (Cambridge, Massachusetts);  Nuh Gedik (Watertown, Massachusetts)
ABSTRACT The generation of photocurrent in an ideal two-dimensional Dirac spectrum is symmetry forbidden. In sharp contrast, a three-dimensional Weyl semimetal can generically support significant photocurrent due to the combination of inversion symmetry breaking and finite tilts of the Weyl spectrum. To realize this photocurrent, a noncentrosymmetric Weyl semimetal is coupled to a pair of electrodes and illuminated with circularly polarized light without any voltage applied to the Weyl semimetal. The wavelength of the incident light can range over tens of microns and can be adjusted by doping the Weyl semimetal to change its chemical potential.
FILED Friday, July 21, 2017
APPL NO 15/656373
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/44 (20130101)
G01J 1/0429 (20130101)
G01J 2001/4446 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 49/003 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090519 Poeppelmeier et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois);  NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Kenneth Poeppelmeier (Evanston, Illinois);  John T. Vaughey (Elmhurst, Illinois);  Jared Incorvati (Evanston, Illinois);  Lindsay Fuoco (Chicago, Illinois)
ABSTRACT An electrochemical cell includes a cathode including an early transition metal fluoro-bronze; an anode including magnesium metal; and an electrolyte; wherein: the early transition metal fluoro-bronze is configured for intercalation of magnesium ions.
FILED Monday, April 20, 2015
APPL NO 14/690823
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 39/00 (20130101)
C01G 39/02 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/08 (20130101)
C01P 2002/50 (20130101)
C01P 2002/54 (20130101)
C01P 2002/72 (20130101)
C01P 2004/03 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/13 (20130101)
H01M 4/38 (20130101) Original (OR) Class
H01M 4/48 (20130101)
H01M 4/381 (20130101)
H01M 4/582 (20130101)
H01M 4/623 (20130101)
H01M 10/054 (20130101)
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090520 Friesen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Arizona Board of Regents Acting For And on Behalf of Arizona State University (Tempe, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Tempe, Arizona)
INVENTOR(S) Cody A. Friesen (Fort McDowell, Arizona);  Jose Antonio Bautista Martinez (Mesa, Arizona)
ABSTRACT Provided in one embodiment is an electrochemical cell, comprising: (i) a plurality of electrodes, comprising a fuel electrode that comprises aluminum and an air electrode that absorbs gaseous oxygen, the electrodes being operable in a discharge mode wherein the aluminum is oxidized at the fuel electrode and oxygen is reduced at the air electrode, and (ii) an ionically conductive medium, comprising an organic solvent; wherein during non-use of the cell, the organic solvent promotes formation of a protective interface between the aluminum of the fuel electrode and the ionically conductive medium, and wherein at an onset of the discharge mode, at least some of the protective interface is removed from the aluminum to thereafter permit oxidation of the aluminum during the discharge mode.
FILED Thursday, December 03, 2015
APPL NO 14/958270
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101) Original (OR) Class
H01M 12/02 (20130101)
H01M 12/06 (20130101)
H01M 12/08 (20130101)
H01M 2300/0002 (20130101)
H01M 2300/0028 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/128 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49108 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090564 Chung et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Total Marketing Services (Puteaux, France)
ASSIGNEE(S) Massachusettes Institute of Technology (Cambridge, Massachusetts);  Total S.A. (Courbevoie, France);  Total Energies Nouvelles Activites USA (Courbevoie, France)
INVENTOR(S) Brice H. V. Chung (Boston, Massachusetts);  Donald R. Sadoway (Cambridge, Massachusetts)
ABSTRACT An electrochemical cell includes a negative electrode comprising a first active metal, a positive electrode comprising a second active metal, and an electrolyte comprising salts of the two active metals, a salt of the cathodic metal and a salt of the anodic metal. In operation, the electrolyte composition varies such that in a charging mode the salt of the anodic salt decreases, while the salt of the cathodic salt increases, and in a discharging mode the salt of the anodic salt increases, while the salt of the cathodic salt decreases. The cell is operational for both storing electrical energy and as a source of electrical energy as part of an uninterruptible power system. The cell is particularly suited to store electrical energy produced by an intermittent renewable energy source.
FILED Thursday, March 13, 2014
APPL NO 14/208218
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/0252 (20130101)
H01M 2/0277 (20130101)
H01M 4/38 (20130101)
H01M 10/39 (20130101)
H01M 10/399 (20130101) Original (OR) Class
H01M 2220/10 (20130101)
H01M 2300/0048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090565 Kung et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Harold H. Kung (Wilmette, Illinois);  Jingmei Shen (Evanston, Illinois);  Mayfair C. Kung (Wilmette, Illinois);  Cary M. Hayner (Evanston, Illinois)
ABSTRACT Thermally responsive materials, porous membranes comprising the thermally responsive materials, and batteries incorporating the porous membranes as thermally responsive separation membranes are provided. Also provided are methods of making the thermally responsive materials. The thermally responsive materials comprise upper critical solution temperature (UCST) polymers covalently bound to a support substrate.
FILED Thursday, April 30, 2015
APPL NO 14/700273
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Separation
B01D 69/02 (20130101)
B01D 69/14 (20130101)
B01D 71/021 (20130101)
B01D 2325/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 2/348 (20130101)
H01M 2/1653 (20130101)
H01M 2/1673 (20130101)
H01M 2/1686 (20130101)
H01M 4/133 (20130101)
H01M 4/382 (20130101)
H01M 4/587 (20130101)
H01M 10/052 (20130101)
H01M 10/4235 (20130101) Original (OR) Class
H01M 2200/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090764 Wilson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  Wayne W. Weaver (Hancock, Michigan);  Rush D. Robinett, III (Tijeras, New Mexico);  Ronald Matthews (Houghton, Michigan)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  Michigan Technological University (Houghton, Michigan)
INVENTOR(S) David G. Wilson (Tijeras, New Mexico);  Wayne W. Weaver (Houghton, Michigan);  Rush D. Robinett, III (Tijeras, New Mexico);  Ronald Matthews (Houghton, Michigan);  Steven F. Glover (Albuquerque, New Mexico)
ABSTRACT A Hamiltonian surface shaping power flow control (HSSPFC) method is used to analyze the meta-stability and adjust pulsed power loads on a DC electric power distribution network. Pulsed power loads are nonlinear, time-variant systems that cause nonlinear limit-cycles. During the on periods of a pulsed load, the system can be in an unstable state and is damped back to stability during the off state of the load. Therefore, over the entire period of the pulse the system may only be assessed as meta-stable. As shown through simulation, HIL and hardware results, the HSSPFC method is more accurate than the other small-signal approaches, such as Eigenvalues, Nyquist, and Floquet theory, and can reveal important details about the transient responses and performance.
FILED Wednesday, January 10, 2018
APPL NO 15/867276
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Systems for Regulating Electric or Magnetic Variables
G05F 3/08 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 1/00 (20130101)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/02 (20130101)
H02M 3/1582 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090826 Wessendorf
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Kurt O. Wessendorf (Albuquerque, New Mexico)
ABSTRACT Various technologies pertaining to a high-impedance current source are described herein. The current source outputs a substantially constant current by way of a first transistor that draws current from a supply. The current source is configured to feed back noise from the supply to a feedback resistor at an input of an operational amplifier (op-amp) by way of a second transistor. The feedback resistor and the op-amp are configured such that responsive to receiving the supply noise feedback, the op-amp drives a gate voltage of the first transistor to cause the first transistor to reject the supply noise and cause the output of the current source to remain substantially constant.
FILED Wednesday, July 26, 2017
APPL NO 15/660296
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Systems for Regulating Electric or Magnetic Variables
G05F 1/467 (20130101)

Amplifiers
H03F 3/3055 (20130101)
H03F 3/45174 (20130101)
H03F 3/45636 (20130101)
H03F 2203/45674 (20130101)

Pulse Technique
H03K 3/012 (20130101)
H03K 3/02315 (20130101) Original (OR) Class
H03K 3/356113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 10085667 Couderc et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Rochester (Rochester, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Jean-Philippe Yves Couderc (Rochester, New York);  Mehmet Kemal Aktas (Penfield, New York);  Tolga Soyata (Pittsford, New York);  Alex Tyndall Page (Rochester, New York)
ABSTRACT An ECG clock electrocardiogram based diagnostic device and method is disclosed. The ECG clock provides a clear visual indicator of heart related anomalies such as Long QT syndrome over a longer span of time than can otherwise be assimilated by a medical practitioner. A variable such as QT interval is represented by a variable length radial hand similar to a watch or clock hand. The circular face of the ECG clock represents the diagnostic time interval, typically 24 hours. The resulting output or plot of the ECG clock portrays a circular or polar mapping of the heart related variable such as QT interval over the diagnostic time interval, facilitating rapid diagnosis of volumes of electrocardiogram data by a medical practitioner that has heretofore not been possible.
FILED Saturday, December 03, 2016
APPL NO 15/368587
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0006 (20130101)
A61B 5/044 (20130101)
A61B 5/0245 (20130101)
A61B 5/0452 (20130101) Original (OR) Class
A61B 5/04017 (20130101)
A61B 5/7203 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086091 Peppas et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Nicholas Peppas (Austin, Texas);  Heidi Culver (Austin, Texas)
ABSTRACT The present disclosure relates to a novel type of recognitive biodegradable nanoparticles and their preparations. In particular, the present disclosure relates to combinations of MIPs and biodegradable nanoparticles.
FILED Thursday, March 24, 2016
APPL NO 15/080165
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5146 (20130101)
A61K 9/5153 (20130101)
A61K 49/0054 (20130101)
A61K 49/0093 (20130101) Original (OR) Class

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 283/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086094 Wei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) He Wei (Cambridge, Massachusetts);  Oliver T. Bruns (Boston, Massachusetts);  Ou Chen (Mansfield, Massachusetts);  Moungi G. Bawendi (Cambridge, Massachusetts)
ABSTRACT A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.
FILED Friday, September 11, 2015
APPL NO 14/852432
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/1839 (20130101) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086336 Getpreecharsawas et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Jirachai Getpreecharsawas (Rochester, New York);  David A. Borkholder (Canandaigua, New York)
ASSIGNEE(S) Rochester Institute of Technology (Rochester, New York)
INVENTOR(S) Jirachai Getpreecharsawas (Rochester, New York);  David A. Borkholder (Canandaigua, New York)
ABSTRACT Ultra-thin nanometer-sealer freestanding polymeric membranes and methods for producing ultra-thin nanometer-scale freestanding recast membranes and ultra-thin nanometer-scale freestanding cross-linked membranes with solid internal backbone are disclosed.
FILED Friday, November 11, 2016
APPL NO 15/349613
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 61/027 (20130101)
B01D 67/0023 (20130101) Original (OR) Class
B01D 67/0088 (20130101)
B01D 69/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086359 Hernandez-Maldonado et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Arturo Hernandez-Maldonado (Mayaguez, Puerto Rico);  Sandra Mendez-Gonzalez (Powder Springs, Georgia);  Sindia Rivera-Jimenez (Mayaguez, Puerto Rico)
ASSIGNEE(S) University of Puerto Rico (San Juan, Puerto Rico)
INVENTOR(S) Arturo Hernandez-Maldonado (Mayaguez, Puerto Rico);  Sandra Mendez-Gonzalez (Powder Springs, Georgia);  Sindia Rivera-Jimenez (Mayaguez, Puerto Rico)
ABSTRACT The invention provides the incorporation of Co2+, Ni2+ or Cu2+ onto the surface of mesoporous SBA-15 via an amino-organic grafting method and the screening of materials as sorbents for the removal of Naproxen from water.
FILED Thursday, March 24, 2011
APPL NO 13/071178
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/10 (20130101)
B01J 20/223 (20130101) Original (OR) Class
B01J 20/28054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086360 Dichtel et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) William R. Dichtel (Wilmette, Illinois);  Alaaeddin Alsbaiee (King of Prussia, Pennsylvania);  Brian J. Smith (Ithaca, New York);  Juan Hinestroza (Ithaca, New York);  Diego Alzate-Sanchez (Evanston, Illinois);  Leilei Xiao (Ithaca, New York);  Yuhan Ling (Ithaca, New York);  Damian Helbling (Ithaca, New York)
ABSTRACT A nucleophilic substitution reaction to crosslink cyclodextrin (CD) polymer with rigid aromatic groups, providing a high surface area, mesoporous CD-containing polymers (P-CDPs). The P-CDPs can be used for removing organic contaminants from water. By encapsulating pollutants to form well-defined host-guest complexes with complementary selectivities to activated carbon (AC) sorbents. The P-CDPs can rapidly sequester pharmaceuticals, pesticides, and other organic micropollutants, achieving equilibrium binding capacity in seconds with adsorption rate constants 15-200 times greater than ACs and nonporous CD sorbents. The CD polymer can be regenerated several times, through a room temperature washing procedure, with no loss in performance.
FILED Monday, November 27, 2017
APPL NO 15/822614
ART UNIT 1673 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 15/40 (20130101)
B01D 53/025 (20130101)
B01D 2253/31 (20130101)
B01D 2253/202 (20130101)
B01D 2253/306 (20130101)
B01D 2253/308 (20130101)
B01D 2257/708 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/24 (20130101) Original (OR) Class
B01J 20/289 (20130101)
B01J 20/3204 (20130101)
B01J 20/3212 (20130101)
B01J 20/3272 (20130101)
B01J 20/3282 (20130101)
B01J 20/3425 (20130101)
B01J 20/3475 (20130101)
B01J 20/3483 (20130101)
B01J 20/28033 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/285 (20130101)
C02F 2101/305 (20130101)
C02F 2101/322 (20130101)
C02F 2103/06 (20130101)

Polysaccharides; Derivatives Thereof
C08B 15/00 (20130101)
C08B 37/0012 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/02 (20130101)
G01N 30/14 (20130101)
G01N 30/30 (20130101)
G01N 30/7206 (20130101)
G01N 30/7233 (20130101)
G01N 33/02 (20130101)
G01N 2030/025 (20130101)
G01N 2030/027 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 999/99 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087137 Yamamoto et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The University of Toledo (Toledo, Ohio)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio)
INVENTOR(S) Kana Yamamoto (Toledo, Ohio);  Sridhar Viamajala (Toledo, Ohio);  Sasidhar Varanasi (Toledo, Ohio);  Kim Nguyen (Toledo, Ohio);  Godwin Abel (Toledo, Ohio);  Ajith Yapa Mudiyanselage (Toledo, Ohio)
ABSTRACT A concise method of producing nylon 11, 12, or 13 precursors from oleic acid or an ester of oleic acid is described. The method involves cross-metathesis reactions as the key C—C bond formation step. Subsequent steps are provided to convert the metathesis product to the corresponding nylon precursors. Also provided are the products of the method.
FILED Monday, June 22, 2015
APPL NO 15/320802
ART UNIT 1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 67/303 (20130101)
C07C 67/303 (20130101)
C07C 67/333 (20130101)
C07C 67/333 (20130101)
C07C 69/675 (20130101)
C07C 69/732 (20130101)
C07C 227/04 (20130101) Original (OR) Class
C07C 227/04 (20130101)
C07C 229/08 (20130101)
C07C 229/08 (20130101)
C07C 253/30 (20130101)
C07C 253/30 (20130101)
C07C 255/23 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087190 Dai et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Mingji Dai (West Lafayette, Indiana);  Mohamed Seleem (West Lafayette, Indiana);  Xianglin Yin (West Lafayette, Indiana)
ABSTRACT The present disclosure relates to novel lactones such as dihydropyrrole-fused furanones, a novel palladium-catalyzed carbonylation method to make the novel lactones, and method of using the novel lactones as anti-fungal and/or anti-bacteria agents.
FILED Tuesday, April 10, 2018
APPL NO 15/949124
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 405/04 (20130101)
C07D 491/20 (20130101)
C07D 491/048 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087213 Chen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
ASSIGNEE(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S) Zhilei Chen (College Station, Texas);  Miguel A. Ramirez (Dunedin, New Zealand);  Dongli Guan (College Station, Texas)
ABSTRACT The present invention includes methods, compositions, uses, and kits for purifying a protein of interest (POI) comprising contacting a first fusion protein comprising the POI fused to the C-terminus of an intein C-fragment with a second fusion protein comprising an intein N-fragment and a purification tag to form a complex between the first fusion protein and the second fusion protein, cleaving the POI from the intein C-fragment, wherein the protein is released from the complex; and isolating the POI; the present invention also includes fusion proteins and vector.
FILED Friday, January 10, 2014
APPL NO 14/760392
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 1/14 (20130101) Original (OR) Class
C07K 1/22 (20130101)
C07K 1/32 (20130101)
C07K 2319/20 (20130101)
C07K 2319/92 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)

Enzymes
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087539 Powell, IV et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
APPLICANT(S) Infinium, Inc. (Natick, Massachusetts)
ASSIGNEE(S) Infinium, Inc. (Natick, Massachusetts)
INVENTOR(S) Adam Clayton Powell, IV (Newton, Massachusetts);  John Strauss (Rindge, New Hampshire);  Robert Steve Tucker (New York, New York);  Jason Brodie Voellinger (Allston, Massachusetts)
ABSTRACT Methods separates a gas comprising providing a first electrode in ion-conducting contact with an electrolyte, providing a second electrode in ion-conducting contact with the electrolyte, wherein the second electrode comprises a liquid metal, providing a displacing material comprising a first surface in contact with the second electrode and a second surface exposed to an environment outside the second electrode, wherein said material permits flow of gas and impedes flow of liquid metal, and establishing a potential between the first and second electrodes, whereby gas flows toward the liquid metal. Other aspects include methods and apparatuses comprising electrodes, electrolytes and displacing materials.
FILED Thursday, June 12, 2014
APPL NO 14/897724
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/02 (20130101)
C25B 9/14 (20130101)

Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor
C25C 3/00 (20130101)
C25C 3/02 (20130101)
C25C 3/04 (20130101)
C25C 7/005 (20130101) Original (OR) Class
C25C 7/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088243 Grama et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Promethean Power Systems, Inc. (Somerville, Massachusetts)
ASSIGNEE(S) Promethean Power Systems, Inc. (Boston, Massachusetts)
INVENTOR(S) Sorin Grama (Boston, Massachusetts);  Matthew H. Dorson (Arlington, Massachusetts);  Rebecca Christianson (Needham, Massachusetts)
ABSTRACT This invention provides a thermal energy battery having an insulated tank containing a multitude of densely packed plastic tubes filled with a phase-change material (PCM, such as ice) that changes from solid to liquid and vice-versa. Energy is stored when the PCM transitions from liquid to solid form, and released when the PCM transitions back from solid to liquid form. The tubes are arranged vertically, span the height of a well-insulated tank, and are immersed in heat transfer fluid (HTF) contained within the tank. The HTF is an aqueous solution with a freezing point temperature below the freezing point temperature of the chosen PCM. The HTF remains in liquid form at all times during the operation of the battery. Diffusers located allow the HTF to be extracted uniformly from the tank, pumped and cooled by a liquid chiller situated outside the tank and then and inserted back into the tank.
FILED Monday, January 30, 2017
APPL NO 15/419974
ART UNIT 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 20/021 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088475 Herr et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Amy E. Herr (Oakland, California);  Robert Lin (Berkeley, California)
ABSTRACT Microfluidic devices for determining whether an analyte is present in a sample are provided. The microfluidic devices include a polymeric medium that includes a first analyte detection domain having a first covalently bound capture member that specifically binds to a first analyte, and a second analyte detection domain having a second covalently bound capture member that specifically binds to a second analyte. Also provided are methods of using the subject microfluidic device, systems and kits that use the subject microfluidic devices, as well as methods of producing the same.
FILED Tuesday, October 21, 2014
APPL NO 15/030232
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)
B01L 3/50273 (20130101)
B01L 3/502707 (20130101)
B01L 3/502761 (20130101)
B01L 2200/12 (20130101)
B01L 2300/12 (20130101)
B01L 2300/069 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0816 (20130101)
B01L 2400/0421 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44726 (20130101)
G01N 27/44791 (20130101)
G01N 33/545 (20130101)
G01N 33/561 (20130101)
G01N 33/6845 (20130101)
G01N 33/54353 (20130101)
G01N 33/54366 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088681 Rolland et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Rochester (Rochester, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Jannick P. Rolland (Pittsford, New York);  Aaron Bauer (Rochester, New York)
ABSTRACT A see-through optical display apparatus includes an image generating component, a tilted primary mirror having a non-flat, freeform, front optical surface, and a tilted secondary mirror having a non-flat, freeform, front optical surface, wherein the apparatus has an external pupil. A method for designing/making a see-through optical display apparatus for displaying an image generated by or on an image generating component of the apparatus.
FILED Friday, May 09, 2014
APPL NO 14/891208
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/23 (20130101)
G02B 17/0816 (20130101)
G02B 27/0012 (20130101)
G02B 27/0172 (20130101) Original (OR) Class
G02B 27/0176 (20130101)
G02B 2027/011 (20130101)
G02B 2027/013 (20130101)
G02B 2027/015 (20130101)
G02B 2027/0178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088891 Petrica et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Paula Petrica (Portland, Oregon);  Adam M. Izraelevitz (Ithaca, New York);  David H. Albonesi (Ithaca, New York);  Christine A. Shoemaker (Ithaca, New York)
ABSTRACT The present disclosure provides methods and systems for managing power in a processor having multiple cores. In one implementation, a microarchitecture of a core within a general-purpose processor may include configurable lanes (horizontal slices through the pipeline) which can be powered on and off independently from each other within the core. An online optimization algorithm may determine within a reasonably small fraction of a time slice a combination of lanes within different cores of the processor to be powered on that optimizes performance under a power constraint budget for the workload running on the general-purpose processor. The online optimization algorithm may use an objective function based on response surface models constructed to fit to a set of sampled data obtained by running the workload on the general-purpose processor with multiple cores, without running the full workload. In other implementations, the power supply to lanes can be gated.
FILED Tuesday, September 23, 2014
APPL NO 14/494568
ART UNIT 2118 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 1/329 (20130101)
G06F 1/3243 (20130101)
G06F 1/3287 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use
Y02D 10/24 (20180101)
Y02D 10/152 (20180101)
Y02D 10/171 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088893 Kulathumani et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S)
INVENTOR(S) Vinod Kulathumani (Morgantown, West Virginia);  David W. Graham (Morgantown, West Virginia);  Brandon David Rumberg (Morgantown, West Virginia)
ABSTRACT According to some embodiments, a sensor network may be provided with re-programmable and/or reconfigurable analog circuitry configured to monitor data collected by the sensor network. The re-programmable and/or reconfigurable analog circuitry may also generate a wakeup signal in response to a defined wakeup event detected by the sensor network.
FILED Friday, May 12, 2017
APPL NO 15/593896
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Electric Digital Data Processing
G06F 1/32 (20130101)
G06F 1/3203 (20130101)
G06F 1/3206 (20130101)
G06F 1/3231 (20130101)
G06F 1/3296 (20130101) Original (OR) Class
G06F 15/7867 (20130101)
G06F 17/5054 (20130101)

Wireless Communication Networks
H04W 4/70 (20180201)

Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use
Y02D 10/12 (20180101)
Y02D 10/13 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089232 Peng et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana)
ASSIGNEE(S) Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) Lu Peng (Baton Rouge, Louisiana);  Ashok Srivastava (Baton Rouge, Louisiana);  Shaoming Chen (Baton Rouge, Louisiana)
ABSTRACT Embodiments of the present invention include methods for increasing off-chip bandwidth. The method includes designing a circuit of switchable pins, replacing a portion of allocated pins of a processor with switchable pins, connecting the processor to a memory interface configured to switch the switchable pins between a power mode and a signal mode, providing a metric configured to identify which of the power mode and the signal mode is most beneficial during 1 millisecond intervals, and switching the switchable pins to signal mode during intervals where the signal mode provides more benefit than the power mode.
FILED Thursday, June 11, 2015
APPL NO 14/737397
ART UNIT 2185 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 12/0862 (20130101) Original (OR) Class
G06F 13/409 (20130101)
G06F 13/1668 (20130101)
G06F 13/4072 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090034 Belashchenko et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska);  THE JOHN HOPKINS UNIVERSITY (Baltimore, Maryland);  INTEL CORPORATION (Santa Clara, California)
INVENTOR(S) Kirill D. Belashchenko (Lincoln, Nebraska);  Oleg Tchernyshyov (Baltimore, Maryland);  Alexey Kovalev (Lincoln, Nebraska);  Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT A magnetoelectric memory cell with domain-wall-mediated switching is implemented using a split gate architecture. The split gate architecture allows a domain wall to be trapped within a magnetoelectric antiferromagnetic (MEAF) active layer. An extension of this architecture applies to multiple-gate linear arrays that can offer advantages in memory density, programmability, and logic functionality. Applying a small anisotropic in-plane shear strain to the MEAF can block domain wall precession to improve reliability and speed of switching.
FILED Wednesday, November 08, 2017
APPL NO 15/807369
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101) Original (OR) Class
G11C 11/1673 (20130101)
G11C 11/1675 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/228 (20130101)
H01L 43/08 (20130101)
H01L 43/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090150 Shohet et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) J. Leon Shohet (Madison, Wisconsin);  Huifeng Zheng (Tigard, Oregon);  Xiangyu Guo (Madison, Wisconsin);  Weiyi Li (Madison, Wisconsin);  Joshua Blatz (Monona, Wisconsin);  Dongfei Pei (Guilderland, New York)
ABSTRACT A method of forming a low dielectric constant (low-k) dielectric is disclosed. The method includes providing a substrate and forming a dielectric including porogens over the substrate. While subjecting the dielectric to a first pressure, the dielectric is exposed to ultraviolet (UV) radiation. The dielectric is also subject to a second pressure less than 1×10−3 Torr. While subjecting the dielectric to the second pressure, the dielectric is exposed to vacuum UV (VUV) radiation having one or more photon energies greater than 7 eV. Since it is difficult for VUV radiation to travel through a medium at a pressure greater than 10 Torr without being absorbed by intermittent materials, subjecting the dielectric to the second pressure creates a medium wherein the dielectric can be exposed to the VUV radiation. By exposing the dielectric to UV and VUV radiation, the dielectric can achieve a reduced dielectric constant and increased mechanical properties.
FILED Wednesday, September 06, 2017
APPL NO 15/696930
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02164 (20130101)
H01L 21/02348 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090463 Lu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Wei Lu (Ann Arbor, Michigan);  Sung Hyun Jo (Ann Arbor, Michigan)
ABSTRACT Non-crystalline silicon non-volatile resistive switching devices include a metal electrode, a non-crystalline silicon layer and a planar doped silicon electrode. An electrical signal applied to the metal electrode drives metal ions from the metal electrode into the non-crystalline silicon layer to form a conducting filament from the metal electrode to the planar doped silicon electrode to alter a resistance of the non-crystalline silicon layer. Another electrical signal applied to the metal electrode removes at least some of the metal ions forming the conducting filament from the non-crystalline silicon layer to further alter the resistance of the non-crystalline silicon layer.
FILED Friday, August 09, 2013
APPL NO 13/963869
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/2472 (20130101)
H01L 27/2481 (20130101)
H01L 45/14 (20130101) Original (OR) Class
H01L 45/085 (20130101)
H01L 45/148 (20130101)
H01L 45/1233 (20130101)
H01L 45/1266 (20130101)
H01L 45/1616 (20130101)
H01L 45/1675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090466 Chan et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ching-Kit Chan (Los Angeles, California);  Patrick A. Lee (Brookline, Massachusetts);  Netanel Lindner (Aviel, Israel);  Gil Refael (Pasadena, California);  Qiong Ma (Cambridge, Massachusetts);  Suyang Xu (Cambridge, Massachusetts);  Nuh Gedik (Watertown, Massachusetts)
ABSTRACT The generation of photocurrent in an ideal two-dimensional Dirac spectrum is symmetry forbidden. In sharp contrast, a three-dimensional Weyl semimetal can generically support significant photocurrent due to the combination of inversion symmetry breaking and finite tilts of the Weyl spectrum. To realize this photocurrent, a noncentrosymmetric Weyl semimetal is coupled to a pair of electrodes and illuminated with circularly polarized light without any voltage applied to the Weyl semimetal. The wavelength of the incident light can range over tens of microns and can be adjusted by doping the Weyl semimetal to change its chemical potential.
FILED Friday, July 21, 2017
APPL NO 15/656373
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/44 (20130101)
G01J 1/0429 (20130101)
G01J 2001/4446 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 49/003 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090552 Matter et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) pH Matter, LLC (Columbus, Ohio)
ASSIGNEE(S) pH Matter, LLC (Columbus, Ohio)
INVENTOR(S) Paul H. Matter (Columbus, Ohio);  Christopher T. Holt (Bexley, Ohio);  Michael G. Beachy (Gahanna, Ohio)
ABSTRACT A liquid fuel battery is described, having a vented case, an internal fuel chamber, and a plurality of substantially planar vertically stacked battery elements having separated fuel-sides and air sides. Such sides are separated by a series of anodic and cathodic seals. In one embodiment, a cathode contains doped carbon nanofibers and may be treated with polytetrafluoroethylene or another hydrophobic material. An anode current collector and/or cathode current collector may contain perforated metal, including metal mesh. Battery elements may be U-shaped to maximize the efficiency of the air-fuel interaction. The cathode is active for oxygen reduction and inactive for fuel oxidation.
FILED Wednesday, July 02, 2014
APPL NO 14/322164
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/96 (20130101)
H01M 8/1009 (20130101)
H01M 8/2455 (20130101) Original (OR) Class
H01M 8/2475 (20130101)
H01M 8/04201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090585 Dinc et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Tolga Dinc (New York, New York);  Harish Krishnaswamy (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Tolga Dinc (New York, New York);  Harish Krishnaswamy (New York, New York)
ABSTRACT Circuits and methods for antenna-based self-interference cancellation are provided. In some embodiments, circuits for antenna-based self-interference cancellation are provided, the circuits comprising: a transmit antenna having a transmit port that receives a transmit signal; a receive antenna having a receive port that is cross-polarized with respect to the transmit port and having an auxiliary port that is co-polarized with respect to the transmit port; and a termination connected to the auxiliary port that reflects a signal received at the auxiliary port as a reflected signal, wherein the reflected signal counters interference caused by the transmit signal at the receive port.
FILED Tuesday, August 23, 2016
APPL NO 15/244869
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/38 (20130101) Original (OR) Class
H01Q 1/525 (20130101)
H01Q 5/314 (20150115)
H01Q 21/06 (20130101)

Transmission
H04B 1/06 (20130101)

Wireless Communication Networks
H04W 16/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090597 Nassar et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Ibrahim Turki Nassar (Lake Forest, California);  Thomas McCrea Weller (Lutz, Florida);  Craig Perry Lusk (Lutz, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Ibrahim Turki Nassar (Lake Forest, California);  Thomas McCrea Weller (Lutz, Florida);  Craig Perry Lusk (Lutz, Florida)
ABSTRACT In some embodiments, a mechanically reconfigurable slot antenna includes an electrically conductive layer having multiple slots, multiple electrically conductive parasitic patches, each patch associated with one of the slots, and a rack-and-pinion mechanism adapted to simultaneously linearly displace at least two of the patches along their associated slots.
FILED Tuesday, May 27, 2014
APPL NO 14/287487
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 13/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090603 Behdad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) Nader Behdad (Madison, Wisconsin);  Meng Li (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Nader Behdad (Madison, Wisconsin);  Meng Li (Madison, Wisconsin)
ABSTRACT A lens is provided. The lens includes a first two-dimensional (2-D) grid of capacitive patches and a first sheet layer. The first sheet layer includes a dielectric sheet and a second 2-D grid of capacitive patches. The dielectric sheet has a front surface and a back surface. The first 2-D grid of capacitive patches is mounted directly on the back surface of the dielectric sheet, and the second 2-D grid of capacitive patches is mounted directly on the front surface of the dielectric sheet. The first 2-D grid of capacitive patches is aligned with the second 2-D grid of capacitive patches to form a time delay circuit at each grid position of the aligned 2-D grids.
FILED Wednesday, May 30, 2012
APPL NO 13/483381
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 15/04 (20130101)
H01Q 15/0026 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10091105 Liu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Yaoqing Liu (Potsdam, New York);  Lan Wang (Germantown, Tennessee)
ASSIGNEE(S)
INVENTOR(S) Yaoqing Liu (Potsdam, New York);  Lan Wang (Germantown, Tennessee)
ABSTRACT A Forwarding Information Base (FIB) caching system and scheme that selects and generates a minimal number of non-overlapping prefixes for the FIB cache to improve computer-based network communications and operations efficiency, accuracy and speed. Because the cached prefixes do not cover any longer prefixes in the full FIB, the present invention thus avoids cache-hiding issues. The system further comprises a FIB caching updating component that systematically handles cache misses, cache replacement, and routing updates.
FILED Monday, October 27, 2014
APPL NO 14/524890
ART UNIT 2465 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/742 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 10087132 Sarker et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Majher I Sarker (Wyndmoor, Pennsylvania);  Helen N. Lew (Wynnewood, Pennsylvania);  Robert A. Moreau (Quakertown, Pennsylvania)
ABSTRACT Disclosed herein are processes for converting an unsaturated fatty acid into a saturated branched-chain fatty acid through a zeolite-catalyzed process and methods of economically regenerating and reusing the zeolite catalyst. The processes include subjecting the unsaturated fatty acid to an isomerization reaction to result in a selective conversion of the unsaturated fatty acid into the saturated branched-chain fatty acid. The reaction occurs in the presence of (i) an activated zeolite catalyst, (ii) an effective amount of water, and (iii) optionally an oligomerization reducing agent. The spent zeolite catalyst may be regenerated by heating to create a regenerated zeolite catalyst that is functional for use as the activated zeolite catalyst.
FILED Thursday, December 29, 2016
APPL NO 15/394015
ART UNIT 1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 29/40 (20130101)
B01J 29/65 (20130101)
B01J 29/90 (20130101)
B01J 29/7007 (20130101)
B01J 38/02 (20130101)

Acyclic or Carbocyclic Compounds
C07C 51/36 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087454 Bilyeu et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
APPLICANT(S) The Curators of the University of Missouri (Columbia, Missouri);  The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia)
INVENTOR(S) Kristin D. Bilyeu (Columbia, Missouri);  James Grover Shannon (Kennett, Missouri);  Jeong-Dong Lee (Daegu, South Korea);  Anh Tung Pham (Columbia, Missouri)
ABSTRACT The present invention is directed to a soybean plant with mutations in FAD2-1A and FAD2-1B. Moreover, the present invention is directed to seeds from said plants with altered ratios of monosaturated and polyunsaturated fats. In particular, the present invention is directed to plants where the plants exhibit elevated levels of oleic acid.
FILED Monday, November 02, 2015
APPL NO 14/929951
ART UNIT 1662 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 1/00 (20130101)
A01H 5/10 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8247 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087461 Bhattacharyya et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Madan K. Bhattacharyya (Ames, Iowa);  Micheline Ngaki (Ames, Iowa)
ABSTRACT The present invention relates to a method of increasing plant resistance to plant pathogens, particularly Sudden Death Syndrome in soybean against Fusarium virguliforme, through the use of Fusarium resistance nucleic acid molecules isolated from Glycine max and Fusarium virguliforme. In these plants, at least one heterologous Fusarium resistance protein is introduced in comparison to the wild-type plants to confer resistance to plant pathogens. The invention relates to transgenic plants and/or plant cells having increased resistance to plant pathogens, to expression vectors, transformed plants and plant cells as well as the use of such plants in a plant breeding program.
FILED Wednesday, January 06, 2016
APPL NO 14/989606
ART UNIT 1662 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0032 (20130101)
C12N 9/1007 (20130101)
C12N 15/8282 (20130101) Original (OR) Class
C12N 15/8283 (20130101)
C12N 15/8285 (20130101)
C12N 15/8286 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6895 (20130101)
C12Q 2600/13 (20130101)

Enzymes
C12Y 105/03011 (20130101)
C12Y 201/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087462 Bhattacharyya et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Madan K. Bhattacharyya (Ames, Iowa);  Prashant Singh (Ames, Iowa);  Sekhar Kambakam (Ames, Iowa)
ABSTRACT The present invention relates to a method of increasing resistance against plant pathogens, particularly Fusarium virguliforme and Phytophthora sojae in transgenic plants and/or plant cells, through the use of non host resistance nucleic acid molecules isolated from Arabidopsis. In these plants, at least one nonhost Arabidopsis resistance protein is introduced in comparison to the wild-type plants to confer resistance to plant pathogens. The invention relates to transgenic plants and/or plant cells having increased resistance to plant pathogens, particularly Fusarium virguliforme and Phytophthora sojae, to expression vectors, transformed plants and plant cells as well as the use of such plants in a plant breeding program.
FILED Wednesday, January 06, 2016
APPL NO 14/989634
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 5/00 (20130101)

Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8282 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087463 Fraser et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Department of Agriculture (USDA)
APPLICANT(S) Malcolm J. Fraser (Granger, Indiana);  Xu Li (Sharon, Massachusetts)
ASSIGNEE(S) University of Notre Dame Du Lac (Notre Dame, Indiana)
INVENTOR(S) Malcolm J. Fraser (Granger, Indiana);  Xu Li (Sharon, Massachusetts)
ABSTRACT The present invention provides a method for transforming an insect genome that has a much enhanced transformation frequency. The vectors and plasmids employed in the method are further described as transposition vectors that include a minimal amount of nucleotide sequence homologous to a 5′ region and a 3′ region of a native piggyBac nucleic acid sequence. The transformed cells or embryos may also be developed into transgenic organisms. Disclosed are minimal piggyBac-based plasmid constructs that comprises a minimal nucleic acid sequence homologous to a 5′ end of a piggyBac nucleic acid sequence (about 60-80 bp, particularly 66 bp) and a relatively long (300 to about 380 bp, particularly 311 bp or 378 bp) continuous nucleic acid sequence homologous to a 3′ end of a piggyBac native nucleic acid sequence. Methods employing these constructs include the use of a helper plasmid. Transformation frequencies employing the constructs are enhanced 100-fold or higher over that transformation frequency obtained using other than the herein described constructs.
FILED Monday, June 19, 2006
APPL NO 11/454947
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101) Original (OR) Class
C12N 15/90 (20130101)
C12N 2800/90 (20130101)
C12N 2800/204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 10087107 Allouche et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S) Louisiana Tech Research Corporation (Ruston, Louisiana)
ASSIGNEE(S) Louisiana Tech Research Corporation (Ruston, Louisiana)
INVENTOR(S) Erez Allouche (Ruston, Louisiana);  Yuri Lvov (Ruston, Louisiana);  Carlos Montes (Ruston, Louisiana);  Anupam Joshi (Ruston, Louisiana)
ABSTRACT A method of controlling the setting time of a geopolymer by coating aluminosilicate particles with nanoparticles to slow the geopolymerization reaction. The coating effectiveness of the nanoparticles may be enhanced by pretreating the aluminosilicate particles with a layer-by-layer assembly of polyelectrolytes. A geopolymer is formed by mixing about 39% to about 66% by weight aluminosilicate source, about 0% to about 40% by weight sand, about 19% to about 33% by weight of alkali activator solution, and about 1% to about 4% nanoparticles.
FILED Thursday, February 02, 2017
APPL NO 15/423110
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 12/00 (20130101)
C04B 12/04 (20130101)
C04B 14/06 (20130101)
C04B 14/044 (20130101)
C04B 14/106 (20130101)
C04B 18/08 (20130101)
C04B 18/08 (20130101)
C04B 18/101 (20130101)
C04B 20/1033 (20130101)
C04B 20/1074 (20130101)
C04B 20/1074 (20130101)
C04B 20/1074 (20130101)
C04B 20/1074 (20130101)
C04B 22/062 (20130101)
C04B 22/062 (20130101)
C04B 22/0093 (20130101)
C04B 28/006 (20130101) Original (OR) Class
C04B 28/006 (20130101)
C04B 28/006 (20130101)
C04B 40/0633 (20130101)
C04B 40/0633 (20130101)
C04B 2103/12 (20130101)
C04B 2103/20 (20130101)
C04B 2103/22 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 40/165 (20151101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/92 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10088584 Griffin et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S) Sean Robert Griffin (Slidell, Louisiana);  Bradley Bruce Lingsch (Diamondhead, Mississippi)
ASSIGNEE(S) Proteus Technologies (Slidell, Louisiana)
INVENTOR(S) Sean Robert Griffin (Slidell, Louisiana);  Bradley Bruce Lingsch (Diamondhead, Mississippi)
ABSTRACT This invention provides a system apparatus and method for ship-towed deployment of a non-linear volumetric array of hydrophones, allowing line-intersect or line-transect sampling of marine mammal populations through passive acoustic monitoring, enabling unambiguous real-time three-dimensional localization of single sounds received through a low-cost, modular, robust, stable, small, light, neutrally to slightly negatively buoyant volumetric array having low self-noise and low flow noise, that avoids putting high tension on the tow cable and that is compatible with standard hydrophones, instrumentation, cabling, and analytical software.
FILED Wednesday, April 27, 2016
APPL NO 15/139811
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/186 (20130101)
G01V 1/201 (20130101) Original (OR) Class
G01V 1/3826 (20130101)
G01V 1/3835 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10090034 Belashchenko et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska);  THE JOHN HOPKINS UNIVERSITY (Baltimore, Maryland);  INTEL CORPORATION (Santa Clara, California)
INVENTOR(S) Kirill D. Belashchenko (Lincoln, Nebraska);  Oleg Tchernyshyov (Baltimore, Maryland);  Alexey Kovalev (Lincoln, Nebraska);  Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT A magnetoelectric memory cell with domain-wall-mediated switching is implemented using a split gate architecture. The split gate architecture allows a domain wall to be trapped within a magnetoelectric antiferromagnetic (MEAF) active layer. An extension of this architecture applies to multiple-gate linear arrays that can offer advantages in memory density, programmability, and logic functionality. Applying a small anisotropic in-plane shear strain to the MEAF can block domain wall precession to improve reliability and speed of switching.
FILED Wednesday, November 08, 2017
APPL NO 15/807369
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/161 (20130101) Original (OR) Class
G11C 11/1673 (20130101)
G11C 11/1675 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/228 (20130101)
H01L 43/08 (20130101)
H01L 43/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 10085662 Schlegel et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Todd T. Schlegel (Nassau Bay, Texas);  Walter B. Kulecz (Houston, Texas)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Todd T. Schlegel (Nassau Bay, Texas);  Walter B. Kulecz (Houston, Texas)
ABSTRACT The present invention includes a method and apparatus for digital to analog conversion and reconstruction of multichannel electrocardiograms. The method may include receiving digital information representative of a plurality of independent signals, producing a plurality of analog outputs from said digital information wherein a first analog output is designated as a common reference, and imposing a predetermined voltage on a second analog output with respect to said common reference, which provides for a substantial recreation of the original independent signals. The apparatus may comprise a processor operable for receiving digital information representative of independent lead signals from a first ECG machine and digital to analog circuitry for substantially reproducing the original lead signals for analysis on a second ECG machine for convenient and efficient second opinions of cardiac data.
FILED Wednesday, March 27, 2013
APPL NO 13/851778
ART UNIT 3766 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0402 (20130101)
A61B 5/04012 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087310 Kornfield et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Julia A. Kornfield (Pasadena, California);  Ming-Hsin Wei (Pasadena, California);  Simon Jones (Whittier, California);  Virendra Sarohia (Altadena, California)
ABSTRACT Described herein are associative polymers capable of controlling one or more physical and/or chemical properties of non-polar compositions and related compositions, methods and systems.
FILED Monday, March 17, 2014
APPL NO 14/217142
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 83/008 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 11/00 (20130101) Original (OR) Class

Compositions of Macromolecular Compounds
C08L 101/02 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/198 (20130101)
C10L 1/1973 (20130101)
C10L 1/1976 (20130101)
C10L 1/2366 (20130101)
C10L 1/2368 (20130101)
C10L 10/00 (20130101)
C10L 10/02 (20130101)
C10L 10/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10089506 Fink et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Patrick W. Fink (Missouri City, Texas);  Gregory Y. Lin (Houston, Texas);  Timothy F. Kennedy (Houston, Texas);  Phong H. Ngo (Friendswood, Texas)
ABSTRACT A system and sensor provides for radio frequency identification (RFID)-enabled information collection. The system includes a ring-shaped element and an antenna. The ring-shaped element includes a conductive ring and an RFID integrated circuit. The antenna is spaced apart from the ring-shaped element and defines an electrically-conductive path commensurate in size and shape to at least a portion of the conductive ring. In an alternate embodiment, the sensor system further comprises a reference ring-shaped element in a fixed relationship with respect to the antenna, with the reference ring-shaped element defining another series circuit to include an electrically-conductive reference ring and a reference RFID integrated circuit. The system may include an interrogator for energizing the ring-shaped element and receiving a data transmission from the RFID integrated circuit that has been energized for further processing by a processor.
FILED Thursday, September 07, 2017
APPL NO 15/697927
ART UNIT 2632 — Digital Communications
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10316 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 10085655 Narayan et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Topera, Inc. (Menlo Park, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia);  Topera, Inc. (Menlo Park, California)
INVENTOR(S) Sanjiv Narayan (La Jolla, California);  Carey Robert Briggs (La Jolla, California);  Ruchir Sehra (Scottsdale, Arizona)
ABSTRACT A system and method are provided for identifying a driver of a source associated with a heart rhythm disorder. Data are accessed from a plurality of sensors representing biological activity in the heart. A local first region of the heart that has repeating activation and determine whether the first region controls a second distant region of the heart for at least a predetermined number of beats is identified. The first local region is assigned as a driver of a source of the heart rhythm disorder, the source including the first local region and the second distant region.
FILED Friday, March 14, 2014
APPL NO 14/774120
ART UNIT 3766 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0006 (20130101)
A61B 5/044 (20130101)
A61B 5/0422 (20130101)
A61B 5/0452 (20130101)
A61B 5/02405 (20130101) Original (OR) Class
A61B 5/02444 (20130101)
A61B 5/04012 (20130101)
A61B 5/6852 (20130101)
A61B 2560/0475 (20130101)
A61B 2562/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10086005 Finkelman et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Cincinnati (Cincinnati, Ohio);  U.S. Department of Veterans Affairs (Washington, District of Columbia);  Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S)
INVENTOR(S) Fred D. Finkelman (Cincinnati, Ohio);  Marat V. Khodoun (Mason, Ohio);  Suzanne C. Morris (Mason, Ohio)
ABSTRACT A method of treating a subject suffering from an allergic disorder is provided, the method including inducing rapid desensitization to an allergen, the rapid desensitization effectuated by: administering to the subject a plurality of equal doses of a first anti-FcεRIα monoclonal antibody, wherein the plurality of equal doses are administered over a 6 to 8 hour period and wherein each dose is lower than a level required to induce shock, thereby inducing rapid desensitization to the allergen. Monoclonal antibodies and methods of co-administering or consecutively administering a combination thereof to effectuate rapid desensitization are also provided.
FILED Friday, December 08, 2017
APPL NO 15/836095
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/137 (20130101)
A61K 31/335 (20130101)
A61K 31/506 (20130101)
A61K 31/573 (20130101) Original (OR) Class
A61K 31/675 (20130101)
A61K 31/4409 (20130101)
A61K 31/4439 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 16/4291 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 10087420 Turner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Taiga Biotechnologies, Inc. (Aurora, Colorado)
ASSIGNEE(S) TAIGA BIOTECHNOLOGIES, INC. (Aurora, Colorado)
INVENTOR(S) Brian Curtis Turner (Denver, Colorado);  Yosef Refaeli (Denver, Colorado);  Gregory Bird (Littleton, Colorado)
ABSTRACT Disclosed are methods for manipulating and expanding stem cell populations, including adult stem cells, the cells produced by such methods, and various protein constructs related thereto.
FILED Friday, June 10, 2016
APPL NO 15/179735
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/82 (20130101)
C07K 14/4747 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0647 (20130101) Original (OR) Class
C12N 7/00 (20130101)
C12N 2501/22 (20130101)
C12N 2501/26 (20130101)
C12N 2501/48 (20130101)
C12N 2501/125 (20130101)
C12N 2501/145 (20130101)
C12N 2501/606 (20130101)
C12N 2501/998 (20130101)
C12N 2501/2303 (20130101)
C12N 2501/2306 (20130101)
C12N 2510/04 (20130101)
C12N 2740/15033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 10087445 Behlke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Integrated DNA Technologies, Inc. (Coralville, Iowa)
ASSIGNEE(S) Integrated DNA Technologies, Inc. (Coralville, Iowa)
INVENTOR(S) Mark Aaron Behlke (Coralville, Iowa);  Richard Owczarzy (Coralville, Iowa);  Yong You (Iowa City, Iowa);  Joseph Alan Walder (Chicago, Illinois);  Kim Lennox (North Liberty, Iowa)
ABSTRACT The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.
FILED Wednesday, November 23, 2016
APPL NO 15/360382
ART UNIT 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/141 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/344 (20130101)
C12N 2310/352 (20130101)
C12N 2310/3529 (20130101)
C12N 2320/51 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6876 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 10085632 Dishong et al.
FUNDED BY
Department of Transportation (USDOT)
APPLICANT(S) North Carolina Department of Transportation (Raleigh, North Carolina)
ASSIGNEE(S) NORTH CAROLINA DEPARTMENT OF TRANSPORTATION (Raleigh, North Carolina)
INVENTOR(S) Randy Dishong (Wake Forest, North Carolina);  Timothy Mark McLawhorn (Washington, North Carolina)
ABSTRACT A mobile workstation system includes a transport vehicle, a mobile workstation, and a deployment system. The transport vehicle includes a cargo volume. The mobile workstation includes: a wheeled carrier; a cabinet supported by the carrier, the cabinet defining at least one enclosed compartment and having selectively openable closures to provide access to the at least one compartment; and a plurality of operational components disposed in the at least one compartment. The mobile workstation is positionable in each of: a storage configuration wherein the operational components are contained in the at least one compartment with the closures in a closed position; and an operational configuration wherein the closures are open to provide access to the operational components and the cabinet forms a desk including a work surface. The deployment system is mounted in the transport vehicle and includes a powered engagement mechanism operable to load and unload the mobile workstation into and from the cargo volume of the vehicle.
FILED Friday, October 07, 2016
APPL NO 15/288464
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Tables; Desks; Office Furniture; Cabinets; Drawers; General Details of Furniture
A47B 31/04 (20130101)
A47B 81/00 (20130101)
A47B 83/001 (20130101)
A47B 83/045 (20130101)
A47B 2031/003 (20130101)
A47B 2083/003 (20130101)
A47B 2220/0091 (20130101)

Diagnosis; Surgery; Identification
A61B 3/02 (20130101) Original (OR) Class

Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects
B60P 1/00 (20130101)
B60P 3/07 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 29/00 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 20/20 (20130101)
G06Q 30/018 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 10090043 Frank
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) David J. Frank (Yorktown Heights, New York)
ABSTRACT A quantum mechanical radio frequency (RF) signaling system includes a transmission line that receives and conducts an RF pulse signal operating at a radio frequency, a first qubit having a quantum mechanical state that is a linear combination of at least two quantum mechanical eigenstates, and a first network of reactive electrical components having an input that is coupled to the transmission line for receiving the RF pulse signal and an output that is coupled to the first qubit. The first network of reactive electrical components attenuates the amplitude of the RF pulse signal and produces a first attenuated RF pulse signal that is applied to the first qubit. The first attenuated RF pulse signal operates at the radio frequency and has a first attenuated amplitude that causes a predefined change in the linear combination of at least two quantum mechanical eigenstates within the first qubit.
FILED Wednesday, November 08, 2017
APPL NO 15/806432
ART UNIT 2631 — Digital Communications
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 99/002 (20130101)

Static Stores
G11C 11/44 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 10089487 Cash et al.
FUNDED BY
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles D. Cash (Highland Park, New Jersey);  Stanislaw Jarecki (Irvine, California);  Charanjit S. Jutla (Elmsford, New York);  Hugo M. Krawczyk (Tarrytown, New York);  Marcel C. Rosu (Ossining, New York);  Michael Steiner (New York, New York)
ABSTRACT A method for searching in an encrypted database includes the following steps. A search is formulated as a conjunct of two or more atomic search queries. One of the conjuncts is selected as a primary atomic search query. Search capabilities are generated for a secondary atomic search query using the primary atomic search query and the secondary atomic search query.
FILED Friday, March 31, 2017
APPL NO 15/476058
ART UNIT 2437 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 17/30864 (20130101)
G06F 21/602 (20130101)
G06F 21/6218 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. Agency for International Development (USAID) 

US 10087239 Chan-Hui et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
U.S. Agency for International Development (USAID)
APPLICANT(S) Theraclone Sciences, Inc. (Seattle, Washington);  The Scripps Research Institute (La Jolla, California);  International AIDS Vaccine Initiative (New York, New York)
ASSIGNEE(S) THERACLONE SCIENCES, INC. (Seattle, Washington);  THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California);  INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York)
INVENTOR(S) Po-Ying Chan-Hui (Bellevue, Washington);  Katherine Doores (San Diego, California);  Michael Huber (Zurich, Switzerland);  Stephen Kaminsky (Bronx, New York);  Steven Frey (Redmond, Washington);  Ole Olsen (Everett, Washington);  Jennifer Mitcham (Redmond, Washington);  Matthew Moyle (Redmond, Washington);  Sanjay K. Phogat (Edison, New Jersey);  Dennis R. Burton (La Jolla, California);  Laura Majorie Walker (San Diego, California);  Pascal Raymond Georges Poignard (San Diego, California);  Wayne Koff (Stony Brook, New York);  Melissa Danielle De Jean De St. Marcel Simek-Lemos (Brooklyn, New York)
ABSTRACT The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies may be characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided.
FILED Thursday, May 12, 2016
APPL NO 15/152630
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/1063 (20130101) Original (OR) Class
C07K 2317/21 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 02, 2018.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
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