FedInvent™ Patents
Patent Details for Tuesday, October 16, 2018
This page was updated on Monday, March 27, 2023 at 05:38 AM GMT
Department of Health and Human Services (HHS)
| US 10098333 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Songtao Shi (Irvine, California); Takayoshi Yamaza (Pasadena, California); Kentaro Akiyama (Fukuoka, Japan) |
| ASSIGNEE(S) | University Of Southern California (Los Angeles, California) |
| INVENTOR(S) | Songtao Shi (Irvine, California); Takayoshi Yamaza (Pasadena, California); Kentaro Akiyama (Fukuoka, Japan) |
| ABSTRACT | This invention discloses a stem cell modified animal model useful as a research tool for investigating aging-related degeneration processes and treatments. The animal model is preferably a rodent subcutaneously transplanted with a mesenchymal stem cell capable of generating a functional bone or marrow element. Also provided are a method for extending the lifespan and improving the quality of life of a subject by subcutaneously transplanting a plurality of mesenchymal stem cells to the subject, wherein the mesenchymal stem cells are capable of generating a functional bone or marrow element. Compositions and source of stem cells suitable for use with the methods of this invention, including stem cells from human exfoliated deciduous teeth (SHED), are also disclosed. Further disclosed is a method for identifying progenitor bone marrow mesenchymal stem cells, and a method for treating SLE-like autoimmune diseases by infusion of mesenchymal stem cells. |
| FILED | Wednesday, December 09, 2009 |
| APPL NO | 13/133638 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 2227/105 (20130101) A01K 2267/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098539 | Konofagou et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Elisa E. Konofagou (New York, New York); Hermes Arytto Salles Kamimura (Ribeirao Preto, Brazil) |
| ABSTRACT | Systems and methods for non-invasive brain stimulation using focused ultrasound are provided. An exemplary method of non-invasive brain stimulation in the brain of a subject can include securing the subject in a fixed position relative to an ultrasound source and providing a focused ultrasound having one or more ultrasound parameters to a location in the brain of the subject, the location and the one or more ultrasound parameters selected to evoke a physical response of the subject, and measuring the physical response of the subject. |
| FILED | Wednesday, February 10, 2016 |
| APPL NO | 15/040926 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/11 (20130101) A61B 3/113 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 5/0205 (20130101) A61B 5/1128 (20130101) A61B 5/4821 (20130101) A61B 5/4848 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) A61N 2007/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098557 | He et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (St. Paul, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Bin He (Minneapolis, Minnesota); Long Yu (Minneapolis, Minnesota) |
| ABSTRACT | A system and method for cardiac activation imaging includes non-invasively or minimally invasively acquiring data about an electrical activation of a heart of a subject using at least one sensor. An activation image of the heart of the subject is reconstructed using a weighted sparse constrained reconstruction. |
| FILED | Monday, November 17, 2014 |
| APPL NO | 15/036961 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/042 (20130101) A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/0402 (20130101) A61B 5/0452 (20130101) A61B 5/742 (20130101) A61B 5/04012 (20130101) Original (OR) Class A61B 5/04085 (20130101) A61B 5/6852 (20130101) A61B 5/7282 (20130101) A61B 6/032 (20130101) A61B 6/503 (20130101) A61B 6/5205 (20130101) A61B 2576/023 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098560 | Narayan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California); Ruchir Sehra (Scottsdale, Arizona) |
| ABSTRACT | A system and method are provided to define a driver of a source associated with a cardiac rhythm disorder of a human heart. A plurality of cardiac signals associated with sensors arranged spatially in relation to an area of the heart are processed to determine a sequence of arcs of rotation in relation to the sensors over a time interval. Rotational directions of the arcs of rotation in the sequence are determined. The area of the heart is identified as controlling the source when the rotational directions of the arcs of rotation in the sequence continue in a same rotational direction in excess of a threshold. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/869687 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/046 (20130101) A61B 5/0422 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098600 | Ning et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York); KONING CORPORATION (West Henrietta, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York); Koning Corporation (West Henrietta, New York) |
| INVENTOR(S) | Ruola Ning (Fairport, New York); Xiaohua Zhang (Rochester, New York); David L. Conover (Rochester, New York); Shaohua Liu (Rochester, New York) |
| ABSTRACT | Cone Beam Breast CT, (CBBCT) is a three-dimensional breast imaging modality with high soft tissue contrast, high spatial resolution and no tissue overlap. CBBCT-based computer aided diagnosis (CBBCT-CAD) technology is a clinically useful tool for breast cancer detection and diagnosis that will help radiologists to make more efficient and accurate decisions. The CBBCT-CAD is able to: 1) use 3D algorithms for image artifact correction, mass and calcification detection and characterization, duct imaging and segmentation, vessel imaging and segmentation, and breast density measurement, 2) present composite information of the breast including mass and calcifications, duct structure, vascular structure and breast density to the radiologists to aid them in determining the probability of malignancy of a breast lesion. |
| FILED | Thursday, June 09, 2016 |
| APPL NO | 15/177949 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/0414 (20130101) A61B 6/463 (20130101) A61B 6/481 (20130101) A61B 6/502 (20130101) Original (OR) Class A61B 6/4085 (20130101) A61B 6/4435 (20130101) A61B 6/5217 (20130101) Electric Digital Data Processing G06F 19/321 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10081 (20130101) G06T 2207/30068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098839 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Liangfang Zhang (San Diego, California); Che-Ming Jack Hu (San Diego, California); Weiwei Gao (La Jolla, California); Jonathan Copp (La Jolla, California) |
| ABSTRACT | The present invention provides for compositions comprising a polymeric hydrogel impregnated with a toxin-absorbing or binding nanoparticle. The present invention also provides for the use of the above compositions for decreasing or neutralizing the effect of a toxin, or for treating or preventing an infection by a microbe that produces a toxin, in a subject. The exemplary toxin is a biological toxin such as a viral, bacterial, fungal, plant or animal toxin. |
| FILED | Friday, March 20, 2015 |
| APPL NO | 15/126342 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 9/0019 (20130101) A61K 9/1629 (20130101) A61K 9/5068 (20130101) A61K 9/5115 (20130101) A61K 9/5153 (20130101) A61K 9/5176 (20130101) A61K 31/49 (20130101) A61K 31/49 (20130101) A61K 35/17 (20130101) A61K 35/18 (20130101) A61K 35/19 (20130101) A61K 35/58 (20130101) A61K 35/63 (20150115) A61K 38/1709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/404 (20130101) A61L 2400/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098857 | Gurtner et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Geoffrey C. Gurtner (Woodside, California); Jayakumar Rajadas (Cupertino, California); Michael Gabriel Galvez (Palo Alto, California); Evgenios Neofytou (Stanford, California) |
| ABSTRACT | Compositions and methods are provided for the prevention and treatment of chronic wounds, including, without limitation, pressure ulcers and diabetic ulcers, by transdermal delivery of an agent that increases activity of HIF-1α in the wound. |
| FILED | Thursday, June 15, 2017 |
| APPL NO | 15/623898 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/1075 (20130101) A61K 9/7023 (20130101) A61K 31/16 (20130101) Original (OR) Class A61K 47/26 (20130101) A61K 47/32 (20130101) A61K 47/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10098871 — Combination therapies for treatment of laminopathies, cellular aging, and atherosclerosis
| US 10098871 | Gordon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Leslie B. Gordon (Foxboro, Massachusetts); Mark W. Kieran (Newton, Massachusetts); Monica E. Kleinman (Sharon, Massachusetts) |
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| INVENTOR(S) | Leslie B. Gordon (Foxboro, Massachusetts); Mark W. Kieran (Newton, Massachusetts); Monica E. Kleinman (Sharon, Massachusetts) |
| ABSTRACT | Provided herein are combination therapies for the treatment of progeroid diseases and conditions, cellular aging, bone diseases, and cardiovascular diseases. The provided combination therapies target the aberrant farnesylation of the mutant lamin A protein progerin and increase progerin clearance. |
| FILED | Monday, July 04, 2016 |
| APPL NO | 15/201525 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/20 (20130101) A61K 9/0053 (20130101) A61K 31/22 (20130101) A61K 31/22 (20130101) A61K 31/55 (20130101) A61K 31/436 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 31/663 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 31/4545 (20130101) A61K 31/4545 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098896 | Brodie et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Angela Brodie (Fulton, Maryland); Vincent C. O. Njar (Glen Burnie, Maryland) |
| ABSTRACT | Described are steroidal C-17 benzoazoles, pyrimidinoazoles (azabenzoazoles) and diazines. Methods for their synthesis are also described, which include methods having a step of nucleophilic vinylic “addition-elimination” substitution reaction of 3β-acetoxy-17-chloro-16-formylandrosta-5,16-diene or analogs thereof and benzoazole or pyrimidinoazole nucleophiles and methods having a palladium catalyzed cross-coupling reaction of 17-iodoandrosta-5,16-dien-3β-ol or analogs thereof with tributylstannyl diazines. The compounds are potent inhibitors of human CYP17 enzyme as well as potent antagonists of both wild type and mutant androgen receptors (AR). The compounds are useful for the treatment of human prostate cancer. |
| FILED | Thursday, May 19, 2016 |
| APPL NO | 15/159117 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) Original (OR) Class Steroids C07J 43/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098897 | Misra et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Sanjay Misra (Rochester, Minnesota); Rajiv Kumar (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials for reducing development of stenosis of arteriovenous fistulas. For example, methods and materials for reducing IEX-1 polypeptide expression or activity within a mammal (e.g., a human) to reduce venous neointimal hyperplasia and/or the development of stenosis of arteriovenous fistulas are provided. |
| FILED | Friday, July 17, 2015 |
| APPL NO | 15/326914 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) A61K 31/593 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098903 | Morrow et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio); The General Hospital Corporation (Boston, Massachusetts); Instituto Nacional de Ciencias Medicas Y Nutricion (Mexico, Mexico) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio); The General Hospital Corporation (Boston, Massachusetts); Instituto Nacional de Ciencias Medicas Y Nutricion (Mexico City, Mexico) |
| INVENTOR(S) | Ardythe L. Morrow (Cincinnati, Ohio); David S. Newburg (Newtonville, Massachusetts); Guillermo M. Ruiz-Palacios (Mexico City, Mexico) |
| ABSTRACT | A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides. |
| FILED | Thursday, April 30, 2015 |
| APPL NO | 14/700232 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/702 (20130101) A61K 31/7016 (20130101) Original (OR) Class A61K 35/20 (20130101) A61K 47/50 (20170801) A61K 47/61 (20170801) A61K 47/62 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098905 | Koeberl |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Dwight D. Koeberl (Durham, North Carolina) |
| ABSTRACT | The present invention relates, in general, to Pompe disease and, in particular, to a methods of treating Pompe disease and to compounds/constructs suitable for use in such methods. |
| FILED | Monday, November 09, 2015 |
| APPL NO | 14/936568 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) Original (OR) Class A61K 48/0008 (20130101) A61K 48/0083 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2799/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098913 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University Of Southern California (Los Angeles, California) |
| INVENTOR(S) | Songtao Shi (Thousand Oaks, California); Shiyu Liu (Los Angeles, California); Fa-ming Chen (Xian, China PRC) |
| ABSTRACT | This disclosure relates in general to a stem cell treatment. This disclosure further relates to a stem cell treatment using a composition comprising stem cells having highly expressed Fas-L. This disclosure further relates to a stem cell treatment of multiple myeloma. This disclosure also relates to a composition comprising stem cells having highly expressed Fas-L. This disclosure also relates to preparation of a composition comprising stem cell having highly expressed Fas-L. This disclosure also relates to preparation of a composition comprising stem cells having highly expressed Fas-L by using a salicylate. An example of salicylate may be aspirin. This disclosure further relates to a stem cell treatment of multiple myeloma. This disclosure also relates to a stem cell treatment of an inflammatory disease and/or autoimmune disease. |
| FILED | Wednesday, September 10, 2014 |
| APPL NO | 14/915105 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) C12N 5/0663 (20130101) C12N 5/0668 (20130101) C12N 2501/25 (20130101) C12N 2501/999 (20130101) C12N 2502/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098929 | Keswani et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); Benaroya Research Institue (Seattle, Washington) |
| INVENTOR(S) | Sundeep Govind Keswani (Cincinnati, Ohio); Paul Laszlo Bollyky (Stanford, California); Swathi Balaji (Cincinnati, Ohio); Timothy M Crombleholme (Denver, Colorado) |
| ABSTRACT | A sustained release formulation of interleukin-10 for wound treatment and related methods is provided. |
| FILED | Friday, August 01, 2014 |
| APPL NO | 14/449657 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 38/2066 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098933 | Georgiou et al. |
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| FUNDED BY |
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| APPLICANT(S) | AERASE, Inc. (Austin, Texas) |
| ASSIGNEE(S) | AERase, Inc. (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas) |
| ABSTRACT | Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise deficient in, argininosuccinate synthetase, with enzymes that deplete L-Arginine in serum. In one embodiment, the present invention contemplates an arginase protein, such as a human Arginase I protein, comprising at least one amino acid substitution and a metal cofactor, said protein comprising an increased catalytic activity when compared with a native human Arginase I. |
| FILED | Tuesday, September 20, 2016 |
| APPL NO | 15/270955 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) A61K 38/00 (20130101) A61K 38/50 (20130101) Original (OR) Class A61K 47/48215 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) Enzymes C12Y 305/03001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098945 | Palese et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee); The United States of America, As Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee); The United States of America, As Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Richard J. Webby (Memphis, Tennessee); Juergen A. Richt (Ames, Iowa); Robert G. Webster (Memphis, Tennessee); Kelly M. Lager (Colo, Iowa) |
| ABSTRACT | The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated swine influenza viruses having modifications to a swine NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. These viruses replicate in vivo, but demonstrate decreased replication, virulence and increased attenuation, and therefore are well suited for use in live virus vaccines, and pharmaceutical formulations. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/375664 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/552 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16034 (20130101) C12N 2760/16121 (20130101) C12N 2760/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098958 | Mirkin et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Amy S. Paller (Wilmette, Illinois); David A. Giljohann (Chicago, California) |
| ABSTRACT | The present invention relates to compositions and methods for delivering an oligonucleotide-functionalized nanoparticle. |
| FILED | Thursday, December 20, 2012 |
| APPL NO | 13/721366 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/5094 (20130101) A61K 31/00 (20130101) A61K 47/48015 (20130101) Original (OR) Class A61K 47/48861 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098971 | Gao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jinming Gao (Plano, Texas); Gang Huang (Plano, Texas); Tian Zhao (Irving, Texas); Xinpeng Ma (Dallas, Texas); Yiguang Wang (Dallas, Texas); Yang Li (Dallas, Texas); Baran D. Sumer (Dallas, Texas) |
| ABSTRACT | The present disclosure relates to polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH. In some aspects, the polymers form a micelle which is sensitive to pH and results in a change in fluorescence based upon the particular pH. In some aspects, the disclosure also provides methods of using the polymers for the imaging of cellular or extracellular environment or delivering a drug. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/369701 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0021 (20130101) A61K 49/0032 (20130101) A61K 49/0041 (20130101) A61K 49/0054 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/30 (20130101) C08F 8/32 (20130101) C08F 8/34 (20130101) C08F 8/42 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 69/103 (20130101) C09B 69/105 (20130101) C09B 69/106 (20130101) C09B 69/109 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6456 (20130101) G01N 33/84 (20130101) G01N 33/582 (20130101) G01N 2021/6432 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099024 | Papania et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Creare, Incorporated (Hanover, New Hampshire) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Creare, Incorporated (Hanover, New Hampshire) |
| INVENTOR(S) | Mark J. Papania (Lilburn, Georgia); James J. Barry (Hanover, New Hampshire); Mark C. Bagley (Grafton, New Hampshire); Darin A. Knaus (Lyme, New Hampshire); Eric M. Friets (Norwich, Vermont); Edward Moynihan (Plainfield, New Hampshire) |
| ABSTRACT | A nasal delivery device can include air-receiving section that has a first passageway therethrough to allow air to pass through the air-receiving section, a powder-reservoir receiving section sized to receive a powder reservoir, and a powder-delivery section that has a second passageway therethrough to allow aerosolized powder from the powder reservoir to pass through the powder-delivery section. The first passageway can have a first end and a second end, with the first end being further from the powder-reservoir receiving section and the second end being at or near the powder-reservoir receiving area. The second end of the air-receiving section can include a flattened region so that air exiting the air-receiving section has a generally flattened profile. |
| FILED | Monday, June 24, 2013 |
| APPL NO | 14/409379 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 15/00 (20130101) A61M 15/002 (20140204) A61M 15/003 (20140204) A61M 15/004 (20140204) A61M 15/06 (20130101) A61M 15/08 (20130101) Original (OR) Class A61M 15/009 (20130101) A61M 15/0013 (20140204) A61M 15/0028 (20130101) A61M 15/0035 (20140204) A61M 15/0036 (20140204) A61M 15/0091 (20130101) A61M 15/0098 (20140204) A61M 16/20 (20130101) A61M 16/0045 (20130101) A61M 16/122 (20140204) A61M 2202/064 (20130101) A61M 2205/195 (20130101) A61M 2205/583 (20130101) A61M 2205/6036 (20130101) A61M 2206/10 (20130101) A61M 2206/14 (20130101) A61M 2206/16 (20130101) A61M 2210/0618 (20130101) A61M 2210/0625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099069 | Partanen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ari Ilkka Mikael Partanen (Bethesda, Maryland); Matthew Robert Dreher (Rockville, Maryland); Pavel Sergeyevich Yarmolenko (Silver Spring, Maryland); Antti Johannes Viitala (Espoo, Finland); Julia Kristina Enholm (Helsingfors, Finland); Max Oskar Kohler (Espoo, Finland) |
| ASSIGNEE(S) | Profound Medical Inc. (Mississauga, California); National Institutes of Health (Bethesda, Maryland) |
| INVENTOR(S) | Ari Ilkka Mikael Partanen (Bethesda, Maryland); Matthew Robert Dreher (Rockville, Maryland); Pavel Sergeyevich Yarmolenko (Silver Spring, Maryland); Antti Johannes Viitala (Espoo, Finland); Julia Kristina Enholm (Helsingfors, Finland); Max Oskar Kohler (Espoo, Finland) |
| ABSTRACT | A therapeutic apparatus (900, 1000) comprising a high intensity focused ultrasound system (904) for heating a target zone (940, 1022). The therapeutic apparatus further comprises a magnetic resonance imaging system (902). The therapeutic apparatus further comprises a memory (952) containing machine executable instructions (980, 982, 984, 986, 988, 990) for execution by a processor (944). Execution of the instructions cause the processor to: generate (702, 802) heating commands (964) which cause the high intensity focused ultrasound system to sonicate the subject; repeatedly acquire (704, 804) magnetic resonance data (954) during execution of the heating commands; repeatedly calculate (706, 806) a spatially dependent parameter (970); and repeatedly modify (708, 808) the heating commands in accordance with the spatially dependent parameter such that within the target zone the spatially dependent parameter remains below a first predetermined threshold and above a second predetermined threshold. |
| FILED | Tuesday, October 11, 2011 |
| APPL NO | 13/879412 |
| ART UNIT | 3737 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/00084 (20130101) A61B 2018/00642 (20130101) A61B 2018/00666 (20130101) A61B 2018/00678 (20130101) A61B 2018/00791 (20130101) A61B 2090/374 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 7/00 (20130101) Original (OR) Class A61N 7/02 (20130101) A61N 2005/1085 (20130101) A61N 2005/1087 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4804 (20130101) G01R 33/4814 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099993 | Dhanya et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
| ASSIGNEE(S) | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Raveendra Panickar Dhanya (La Jolla, California); Douglas J. Sheffler (La Jolla, California); Nicholas D. P. Cosford (La Jolla, California); Russell Dahl (La Jolla, California) |
| ABSTRACT | Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor positive allosteric modulators (PAMS), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds. |
| FILED | Monday, April 06, 2015 |
| APPL NO | 15/301697 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 49/84 (20130101) C07C 59/90 (20130101) C07C 65/40 (20130101) Original (OR) Class C07C 69/92 (20130101) C07C 235/46 (20130101) C07C 235/54 (20130101) C07C 251/48 (20130101) C07C 255/56 (20130101) C07C 259/10 (20130101) C07C 311/51 (20130101) C07C 2601/02 (20170501) C07C 2601/08 (20170501) Heterocyclic Compounds C07D 213/50 (20130101) C07D 213/55 (20130101) C07D 213/64 (20130101) C07D 213/68 (20130101) C07D 213/70 (20130101) C07D 213/79 (20130101) C07D 213/80 (20130101) C07D 239/26 (20130101) C07D 241/12 (20130101) C07D 241/24 (20130101) C07D 257/04 (20130101) C07D 271/06 (20130101) C07D 271/07 (20130101) C07D 277/24 (20130101) C07D 285/08 (20130101) C07D 285/12 (20130101) C07D 295/16 (20130101) C07D 295/26 (20130101) C07D 295/108 (20130101) C07D 307/42 (20130101) C07D 307/54 (20130101) C07D 307/68 (20130101) C07D 311/16 (20130101) C07D 333/24 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) C07F 5/025 (20130101) C07F 7/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100022 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Kevin R. Lynch (Charlottesville, Virginia); Webster L. Santos (Blacksburg, Virginia) |
| ABSTRACT | Sphingosine kinases are enzymes that catalyze the biosynthesis of sphingosine-1-phosphate. The invention provides compounds that are effective for inhibition of sphingosine kinase type 1, sphingosine kinase type 2, or both. Certain compounds are selective for sphingosine kinase type 2 relative to sphingosine kinase type 1. Compounds of the invention can be used in treatment of a range of diseases wherein increasing the level of sphingosine-1-phosphate in blood is medically indicated. Diseases that can be treated by administration of an effective dose of a compound of the invention include a neoplastic disease that involves excess vascular growth; macular degeneration or diabetic retinopathy; an allergic disease such as asthma, an inflammatory disease of the eye such as uveitis, scleritis, or vitritis; an inflammatory disease of the kidney; a fibrotic disease; atherosclerosis; or pulmonary arterial hypertension. A compound of the invention can be used to improve the integrity of a vascular barrier in a disease where the vascular barrier is disrupted, such as cancer or Alzheimer's disease. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 15/516333 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/03 (20130101) A61K 31/42 (20130101) Acyclic or Carbocyclic Compounds C07C 279/16 (20130101) Heterocyclic Compounds C07D 249/08 (20130101) C07D 271/06 (20130101) Original (OR) Class C07D 285/12 (20130101) C07D 413/04 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100037 | Bogyo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Matthew S. Bogyo (Redwood City, California); Martijn Verdoes (Nijmegen, Netherlands) |
| ABSTRACT | Activity-based probe compounds for use in labeling a cysteine protease are provided. The compounds are targeted to the protease through a specific targeting element. The compounds additionally include a detectable element, such as a fluorescent label, a radiolabel, or a chelator. In some cases, the compounds additionally include a quenching element that is released upon reaction with the protease. Also provided are compositions comprising the compounds and methods for using the compounds, for example in labeling a protease in an animal and in visualizing a tumor in an animal. |
| FILED | Saturday, March 15, 2014 |
| APPL NO | 14/777024 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0034 (20130101) A61K 49/0041 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100074 | Gervay-Hague et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jacquelyn Gervay-Hague (Davis, California); Matthew Schombs (Oxford, United Kingdom) |
| ABSTRACT | The present invention provides novel, regioselectively-acylated oligosaccharide compounds and methods for preparing them. In another aspect, the. invention provides a method for preparing a selectively-acylated oligosaccharide. The method includes forming a reaction mixture containing a protected oligosaccharide and an acylating agent. The protected oligosaccharide includes at least three hydroxyl moieties and each hydroxyl moiety is protected with a silyl protecting group. The reaction mixture is formed under conditions sufficient to selectively replace at least one silyl protecting group with a —C(0)-C1_6 alkyl group, and the selectively-acylated oligosaccharide comprises at least one —C(0)-C1_6 alkyl group and at least one silyl protecting group. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 14/975537 |
| ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/06 (20130101) C07H 13/04 (20130101) Original (OR) Class C07H 23/00 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100087 | O'Reilly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Richard J. O'Reilly (Roxbury, Connecticut); Ekaterina Doubrovina (West Orange, New Jersey); Annamalai Selvakumar (Bronx, New York) |
| ABSTRACT | This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT-1-expressing cancer, comprising peptides derived from the WT-1 protein. |
| FILED | Tuesday, May 30, 2017 |
| APPL NO | 15/608964 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2039/5158 (20130101) A61K 2039/55505 (20130101) A61K 2039/55516 (20130101) A61K 2039/55522 (20130101) A61K 2039/55527 (20130101) A61K 2039/55566 (20130101) A61K 2039/55577 (20130101) A61K 2039/55594 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100090 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Richard E. Lee (Cordova, Tennessee); Ying Zhao (Memphis, Tennessee); Liu Jiuyu (Collierville, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators with the ClpP endopeptidase; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of search in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, March 04, 2016 |
| APPL NO | 15/554707 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/15 (20130101) A61K 45/06 (20130101) Peptides C07K 11/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100102 | Lai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Samuel Lai (Carrboro, North Carolina); Ying-Ying Wang (Baltimore, Maryland); Arthi Kannan (Morrisville, North Carolina); Kennetta Nunn (Durham, North Carolina); Durai Babu Subramani (Chapel Hill, North Carolina); Richard Cone (Baltimore, Maryland) |
| ABSTRACT | The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating pathogen infection and providing contraception. In particular, the presently-disclosed subject matter relates to inhibiting and treating pathogen infection and providing contraception in a subject using compositions and antibodies capable of trapping pathogens or sperm in mucus, thereby inhibiting transport of pathogens or sperm across mucus secretions. The subject matter further relates to methods for monitoring the effectiveness of vaccines by detecting antibodies capable of trapping pathogens in mucus. |
| FILED | Tuesday, October 29, 2013 |
| APPL NO | 14/438511 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/087 (20130101) C07K 16/1235 (20130101) Original (OR) Class C07K 2317/41 (20130101) C07K 2317/71 (20130101) C07K 2317/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100113 | Littman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dan R. Littman (New York, New York); Jun R. Huh (Newton, Massachusetts) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Dan R. Littman (New York, New York); Jun R. Huh (Newton, Massachusetts) |
| ABSTRACT | Methods are presented herein for reducing the risk of developing a psychiatric disorder (e.g., autism like disorder) in a fetus involving administering an inhibitor of T helper 17 (Th17) cell activity to the mother of the fetus, while the mother is pregnant with the fetus at risk. Also encompassed herein is a method for treating a fetus in utero to reduce the risk of abnormal cortical development that arises from Th17 cell-mediated activity. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/042976 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/244 (20130101) Original (OR) Class C07K 16/2866 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6869 (20130101) G01N 2800/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100279 | Nicholas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Cory R. Nicholas (San Francisco, California); John L. Rubenstein (San Francisco, California); Arnold R. Kriegstein (Mill Valley, California); Arturo Alvarez-Buylla (Woodside, California) |
| ABSTRACT | Methods and systems for generating MGE precursor cells in vitro as well as compositions of enriched MGE precursor cells are provided. The methods and systems provide efficient production of MGE precursors. The methods and systems disclosed herein provide functional MGE precursors which differentiate into functional GABAergic interneurons. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/763397 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0618 (20130101) Original (OR) Class C12N 5/0619 (20130101) C12N 2500/90 (20130101) C12N 2501/13 (20130101) C12N 2501/41 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100291 | Chavez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Alejandro Chavez (Brookline, Massachusetts); Frank Poelwijk (Dallas, Texas); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | Methods of making deletion mutants of Cas9 proteins and making chimeric Cas9 proteins are described. The Cas9 N- and C-terminal domains may play critical roles in crRNAitracrRNA binding and/or PAM selectivity. To analyze activity, a series of domain exchange mutants between NM and STI (Streptococcus thermophilus Cas9) were made, replacing the N and/or C terminus of NM (Neisseria meningitides Cas9) with the homologous region from STI. The chimeric proteins were then tested using the transcriptional reporter assay described herein altering the guideRNA and/or Cas9 specific PAM within the reporter to determine the influence of the domain exchanges on protein specificity. None of the N-terminal domain swaps between NM and STI endowed NM with novel properties. The C-terminal exchange generated a NM-STI hybrid that was capable of interacting with the STI crRNAitracrRNA complex and was further able to suppress a reporter with a STI specific PAM. |
| FILED | Wednesday, November 19, 2014 |
| APPL NO | 15/037696 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Enzymes C12Y 301/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/922 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100308 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Ta-Yuan Chang (Etna, New Hampshire); Catherine C. Y. Chang (Etna, New Hampshire); Yohei Shibuya (West Lebanon, New Hampshire); Zhaoyang Niu (Hanover, New Hampshire) |
| ABSTRACT | The present invention features methods for stimulating clearance of misfolded or aggregated proteins or peptides in microglia or neurons, and treating neurodegenerative diseases associated with such pathology in brain by selectively inhibiting the expression or activity of Acyl-CoA: Cholesterol Acyltransferase 1, but not Acyl-CoA: Cholesterol Acyltransferase 2. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 15/313642 |
| ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/255 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2710/10043 (20130101) C12N 2710/10071 (20130101) Enzymes C12Y 203/01009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100309 | Gelfand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Jewish Health (Denver, Colorado) |
| ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
| INVENTOR(S) | Erwin W. Gelfand (Cherry Hills Village, Colorado); Meiqin Wang (Glendale, Colorado); Yi Jia (Centennial, Colorado) |
| ABSTRACT | The present invention relates to methods and compositions for treating and/or preventing allergic diseases or conditions by inhibiting one or more components of the steroidogenic pathway. |
| FILED | Thursday, November 10, 2016 |
| APPL NO | 15/348345 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/444 (20130101) A61K 31/451 (20130101) A61K 31/7105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) Enzymes C12Y 114/15006 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/826 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100314 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Don J. Diamond (Glendora, California); Edwin Manuel (San Diego, California) |
| ABSTRACT | In one embodiment, a single modality cancer immunotherapy regimen that includes a therapeutic composition is provided. Such a therapeutic composition may include a Salmonella strain comprising a plasmid that expresses an shRNA molecule that suppresses the expression of an immunosuppressive target and suppresses tumor growth. In some aspects, the Salmonella strain is an attenuated Salmonella typhimurium strain. In other aspects, the immunosuppressive target is STAT3, IDO1, IDO2, Arginase 1, iNOS, CTLA-4, TGF-β, IL-10, pGE2 or VEGF. In one embodiment, the immunosuppressive target is IDO1 or Arg1 and the shRNA molecule is any one of SEQ ID NO:5-14. |
| FILED | Monday, September 26, 2016 |
| APPL NO | 15/276645 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/39 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/1136 (20130101) C12N 15/1137 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/32 (20130101) C12N 2330/50 (20130101) Enzymes C12Y 113/11052 (20130101) C12Y 305/03001 (20130101) Technologies for Adaptation to Climate Change Y02A 50/484 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100332 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Ki-Bum Lee (Monmouth Junction, New Jersey); Sahishnu Patel (Lake Hiawatha, New Jersey) |
| ABSTRACT | This application discloses the compositions comprising biologically active synthetic nanoparticle constructs and methods of use thereof to modify gene expression including transcriptional activation and transcriptional repression. |
| FILED | Monday, August 25, 2014 |
| APPL NO | 14/913804 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) Original (OR) Class C12N 2810/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100346 | Gottwein et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hvidovre Hospital (Hvidovre, Denmark); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | Hvidovre Hospital (Hvidovre, Denmark); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Judith M. Gottwein (Frederiksberg C, Denmark); Troels Kasper Hoyer Scheel (Copenhagen NV, Denmark); Robert Purcell (Bethesda, Maryland); Jens Bukh (Praestø, Denmark) |
| ABSTRACT | The present invention relates to molecular approaches to the production of nucleic acid sequences, which comprises the genome of infectious hepatitis C virus. In particular, the invention provides nucleic acid sequences which comprise the genomes of infectious hepatitis C viruses of either genotype 3a (strain S52) or genotype 4a (strain ED43). The invention therefore relates to the use of the nucleic acid sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and in the development of screening assays for the identification of antiviral agents for HCV. The invention therefore also relates to the use of viral particles derived from laboratory animals infected with S52 and ED43 viruses. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 15/581603 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24221 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100349 | Macleod et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Iain J. Macleod (Boston, Massachusetts); Christopher F. Rowley (Boston, Massachusetts); Max Essex (Sharon, Massachusetts) |
| ABSTRACT | Methods and compositions for determining the presence of a polymorphism at a target nucleotide position in a plurality of target nucleic acid sequences is provided. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 15/026031 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 2525/15 (20130101) C12Q 2525/161 (20130101) C12Q 2525/179 (20130101) C12Q 2525/191 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100350 | Breslauer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kenneth J. Breslauer (Edison, New Jersey); William H. Braunlin (New York, New York); Leslie C. Beadling (Wilmington, Delaware); Jens Volker (Piscataway, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Kenneth J. Breslauer (Edison, New Jersey); William H. Braunlin (New York, New York); Leslie C. Beadling (Wilmington, Delaware); Jens Volker (Piscataway, New Jersey) |
| ABSTRACT | Molecular constructs, populations thereof, arrays, compositions, methods and kits for differentiating a target molecule from an off-target molecule are provided. |
| FILED | Monday, May 07, 2012 |
| APPL NO | 14/110618 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6811 (20130101) C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6837 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 2525/205 (20130101) C12Q 2525/205 (20130101) C12Q 2525/205 (20130101) C12Q 2525/205 (20130101) C12Q 2527/107 (20130101) C12Q 2527/107 (20130101) C12Q 2527/107 (20130101) C12Q 2527/107 (20130101) C12Q 2537/137 (20130101) C12Q 2537/137 (20130101) C12Q 2537/137 (20130101) C12Q 2537/137 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/163 (20130101) C12Q 2537/163 (20130101) C12Q 2537/163 (20130101) C12Q 2537/163 (20130101) C12Q 2565/525 (20130101) C12Q 2565/525 (20130101) C12Q 2565/525 (20130101) C12Q 2565/525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100356 | Esfandyarpour et al. |
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| FUNDED BY |
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| APPLICANT(S) | GenapSys, Inc. (Redwood City, California) |
| ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Kosar Baghbani Parizi (Los Altos, California); Eric S. Nordman (Palo Alto, California) |
| ABSTRACT | A method comprises magnetically holding a bead carrying biological material (e.g., nucleic acid, which may be in the form of DNA fragments or amplified DNA) in a specific location of a substrate, and applying an electric field local to the bead to isolate the biological material or products or byproducts of reactions of the biological material. For example, the bead isolated from other beads having associated biological material. The electric field in various embodiments concentrates reagents for an amplification or sequencing reaction, and/or concentrates and isolates detectable reaction by-products. For example, by isolating nucleic acids around individual beads, the electric field can allow for clonal amplification, as an alternative to emulsion PCR. In other embodiments, the electric field isolates a nanosensor proximate to the bead, to facilitate detection of at least one of local pH change, local conductivity change, local charge concentration change and local heat. The beads may be trapped in the form of an array of localized magnetic field regions. |
| FILED | Monday, September 21, 2015 |
| APPL NO | 14/859725 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/10 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2200/0689 (20130101) B01L 2300/12 (20130101) B01L 2300/089 (20130101) B01L 2300/123 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) B01L 2400/0415 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) B01L 2400/0424 (20130101) B01L 2400/0427 (20130101) B01L 2400/0478 (20130101) B01L 2400/0655 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/30 (20130101) B03C 1/286 (20130101) B03C 1/288 (20130101) B03C 5/005 (20130101) B03C 5/022 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2563/143 (20130101) C12Q 2563/143 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/40 (20130101) G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/5438 (20130101) G01N 2001/4038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100366 | Davare |
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| FUNDED BY |
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| APPLICANT(S) | Monika A. Davare (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Monika A. Davare (Portland, Oregon) |
| ABSTRACT | The emergence of resistance to targeted therapy is a recurrent clinical challenge and requires development and validation of secondary agents with improved activity. Accompanied by experimental cell-based and structural validation, this report of a near complete response to cabozantinib in a ROS1-rearranged lung adenocarcinoma patient with acquired resistance to crizotinib mediated by a novel CD74-ROS1 D2033N solvent-front mutation provides the first clinical example of crizotinib resistance overcome by targeted therapy in a ROS1-rearranged malignancy. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/356133 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100367 | Krichevsky et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Anna M. Krichevsky (Brookline, Massachusetts); Nadiya Teplyuk (Boston, Massachusetts); Santosh Kesari (San Diego, California); Brit Mollenhauer (Kassel, Germany) |
| ABSTRACT | The use of specific microRNAs (miRNAs) present in CSF as biomarkers for particular brain malignancies and disease activity. |
| FILED | Tuesday, June 13, 2017 |
| APPL NO | 15/621356 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100368 | Driebe et al. |
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| FUNDED BY |
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| APPLICANT(S) | Elizabeth Driebe (Flagstaff, Arizona); David Engelthaler (Flagstaff, Arizona); Jolene Bowers (Flagstaff, Arizona); Paul Keim (Flagstaff, Arizona) |
| ASSIGNEE(S) | The Translational Genomics Research Institute (Phoenix, Arizona); Arizona Board of Regents on behalf of Northern Arizona University (Flagstaff, Arizona) |
| INVENTOR(S) | Elizabeth Driebe (Flagstaff, Arizona); David Engelthaler (Flagstaff, Arizona); Jolene Bowers (Flagstaff, Arizona); Paul Keim (Flagstaff, Arizona) |
| ABSTRACT | The present invention provides multiplex assays, methods and kits that may be used to detect and confirm the presence of MRSA in a sample. The methods include real-time PCR assays, and the kits and compositions include oligonucleotides used as primers and probes. The present invention further comprises assays useful to identify and differentiate MRSA, MSSA, MRSE, MSSE, MRCNS and MSCNS in a sample. |
| FILED | Friday, March 18, 2011 |
| APPL NO | 13/051755 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100372 | Plemper et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia State University and Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Richard K. Plemper (Decatur, Georgia); Dan Yan (Lilburn, Georgia) |
| ABSTRACT | An RSV reporter strain that can be used for high-throughput drug discovery is disclosed. Also disclosed is a recombinant RSV vector that contains an RSV genome encoding the disclosed RSV reporter strain operably linked to an expression control sequence. Also disclosed is an infectious RSV virion produce by expression of the disclosed recombinant RSV vector in a host cell. Also disclosed is a recombinant nucleic acid that comprises an RSV F protein having an escape mutation operably linked to a heterologous expression control sequence. Also disclosed are methods of screening for antiviral agents using the disclosed RSV reporter strains. |
| FILED | Thursday, June 18, 2015 |
| APPL NO | 15/319642 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) C12N 2760/18521 (20130101) C12N 2760/18543 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) Original (OR) Class Enzymes C12Y 113/12005 (20130101) C12Y 113/12007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101280 | Ranieri et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Nicola Ranieri (Maineville, Ohio); Mark R. Witkowski (West Chester, Ohio); Robert Hammaker (Manhattan, Kansas); William G. Fateley (Green Valley, Arizona) |
| ABSTRACT | Featured are a device (20) and method for the detection of counterfeit pharmaceuticals and/or packaging therefore. Counterfeit pharmaceuticals are detected by visual inspection upon exposing a suspected counterfeit pharmaceutical to one or more light sources having different wavelengths, and observing the differences in color and/or brightness between the suspected counterfeit and a genuine pharmaceutical/packaging. In further embodiments, a image acquisition device acquires an image showing color and/or other visual effect(s) brightness of the suspect counterfeit and this image is compared to an image of a authentic pharmaceutical/packaging. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332908 |
| ART UNIT | 2483 — Recording and Compression |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/10 (20130101) G01J 3/32 (20130101) G01J 3/50 (20130101) G01J 3/0272 (20130101) G01J 3/501 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) G01N 21/33 (20130101) G01N 21/64 (20130101) G01N 21/95 (20130101) Original (OR) Class G01N 21/3563 (20130101) G01N 21/9508 (20130101) G01N 33/15 (20130101) G01N 2201/0221 (20130101) G01N 2201/0627 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00577 (20130101) G06K 9/2018 (20130101) G06K 9/4652 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101299 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Shan X. Wang (Portola Valley, California); Richard S. Gaster (Los Altos, California); Liang Xu (Nanchang, China PRC); Shu-Jen Han (Cortlandt Manor, New York); Robert Wilson (Campbell, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Standford Junior University (Palo Alto, California) |
| INVENTOR(S) | Shan X. Wang (Portola Valley, California); Richard S. Gaster (Los Altos, California); Liang Xu (Nanchang, China PRC); Shu-Jen Han (Cortlandt Manor, New York); Robert Wilson (Campbell, California) |
| ABSTRACT | Methods for quantitatively determining a binding kinetic parameter of a molecular binding interaction are provided. Aspects of embodiments of the methods include: producing a magnetic sensor device including a magnetic sensor in contact with an assay mixture including a magnetically labeled molecule to produce a detectable molecular binding interaction; obtaining a real-time signal from the magnetic sensor; and quantitatively determining a binding kinetics parameter of the molecular binding interaction from the real-time signal. Also provided are systems and kits configured for use in the methods. |
| FILED | Friday, March 11, 2011 |
| APPL NO | 13/046368 |
| ART UNIT | 1677 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) Original (OR) Class G01N 33/557 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101323 | Haselton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Frederick Haselton (Nashville, Tennessee); Joshua R. Trantum (Nashville, Tennessee) |
| ABSTRACT | The present invention provides simple and inexpensive assays for the detection of virtually any analyte in any sample that is in liquid form or that can be solubilized. The assays utilize the fluid dynamics of drop evaporation whereby soluble materials, including analytes and particles binding thereto, are drawn to the center of the drop by Marangoni flow and ultimately form a concentrated residual spot. The presence or absence of certain reagents can then be detected through a number of different approaches. |
| FILED | Wednesday, October 22, 2014 |
| APPL NO | 14/520541 |
| ART UNIT | 1677 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54306 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101324 | Gonzalez-Sapienza et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Universidad de la República, Facultad de Química (Montevideo C.P, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Gualberto Gonzalez-Sapienza (Montevideo, Uruguay); Bruce Hammock (David, California); Andres Gonzalez-Techera (Montevideo, Uruguay); Lucia Vanrell (Montevideo, Uruguay); Gabriel Lassabe (Canelones, Uruguay) |
| ABSTRACT | A method for noncompetitive detection of a small analyte using nanopeptamers, and devices useful for performing the methods. Nanopeptamers include a self-associating oligomeric protein that is attached to peptides that bind to an immune complex between the target analyte and a capture antibody. The noncompetitive methods allow for the direct detection of small analytes with increased sensitivity over competitive methods directed to the same target analyte, and provide a positive readout which is useful for rapid tests and on-site detection of small analytes such as such as pesticides, persistent organic pollutants, explosives, toxins, medicinal and abused drugs, and hormones. |
| FILED | Tuesday, November 26, 2013 |
| APPL NO | 14/648242 |
| ART UNIT | 1677 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54306 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101329 | Picker et al. |
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| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Louis Picker (Portland, Oregon); Klaus Frueh (Portland, Oregon); Scott G. Hansen (Portland, Oregon); Colin Powers (San Diego, California) |
| ABSTRACT | This invention also relates to recombinant vectors expressing one or more of the human CMV (HCMV) glycoproteins US2, US3, US6 and US11 or corresponding functional rhesus CMV (RhCMV) homologues Rh182, Rh184, Rh185 or Rh189, methods of making them, uses for them, expression products from them, and uses for the expression products. This invention also relates to recombinant cytomegalovirus vectors vectors lacking one or more of the glycoproteins, methods of making them, uses for them, expression products from them, and uses for the expression products. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 15/374938 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/02 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 39/245 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10343 (20130101) C12N 2710/16134 (20130101) C12N 2710/16143 (20130101) C12N 2710/24143 (20130101) C12N 2740/10034 (20130101) C12N 2740/15043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101330 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | MagArray, Inc. (Milpitas, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | MagArray, Inc. (Milpitas, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Shan Xiang Wang (Palo Alto, California); Viswam Siva Nair (Menlo Park, California); Heng Yu (Campbell, California); Michael J. Beggs (San Jose, California); Luis Carbonell (Huntington Beach, California) |
| ABSTRACT | Aspects of the present disclosure include methods of producing a circulating analyte profile of a subject. The methods include contacting a blood sample from a subject with a panel of probes for specific binding to analytes, and detecting the presence or absence of binding of the analytes to probes of the panel of probes. Also provided are sensor devices including a panel of capture probes and useful, e.g., for practicing the methods of the present disclosure. |
| FILED | Thursday, September 15, 2016 |
| APPL NO | 15/266848 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57423 (20130101) Original (OR) Class G01N 33/57488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101424 | Levine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Evan G. Levine (Redwood City, California); Brian A. Hargreaves (Menlo Park, California) |
| ABSTRACT | Accelerated 3D multispectral imaging (MSI) on a magnetic resonance imaging (MRI) system uses phase-encoding in two dimensions and frequency-encoding in the third. The method generates randomized k-space undersampling patterns that vary between different spectral bins to determine k-space samples to be acquired in each spectral bin; orders k-space samples into echo trains that determine gradient waveforms; initializes the gradient waveforms, RF waveforms, and timing information; plays the gradient and RF waveforms using the timing information to excite and refocus different spatial and spectral bin regions; acquires undersampled MRI signal data on the MRI system from the spatial and spectral bin regions; uses robust principal component analysis to reconstruct on-resonance images and off-resonance images represented as sets of low rank and sparse matrices from the undersampled MRI signal data; combines the on-resonance images and off-resonance images to yield a final image; and presents the final image on a display. |
| FILED | Wednesday, December 21, 2016 |
| APPL NO | 15/387616 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4818 (20130101) G01R 33/4835 (20130101) Original (OR) Class G01R 33/5611 (20130101) G01R 33/56536 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102441 | Reda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Fitsum A. Reda (Nashville, Tennessee); Jack H. Noble (Nashville, Tennessee); Benoit Dawant (Nashville, Tennessee); Robert F. Labadie (Nashville, Tennessee) |
| ABSTRACT | A method for automatic segmentation of intra-cochlear anatomy in post-implantation CT image of bilateral cochlear implant recipients includes coarsely segmenting a labyrinth with a labyrinth surface chosen from a library of inner ear anatomy shapes; creating a target specific ASM for each of the labyrinth and the SOIs using a set of inner ear anatomy surfaces selected from the library of inner ear anatomy shapes such that the set of inner ear anatomy surfaces has the smallest dissimilarity quantity with the coarsely localized labyrinth surface in the post-implantation CT image; refining the coarsely segmented labyrinth surface by performing an ASM-based segmentation of the labyrinth using the target-specific ASM of the labyrinth to obtain a segmented labyrinth; and fitting the points of the target-specific ASM of the SOIs to their corresponding points on the segmented labyrinth to segment the SOIs in the post-implantation CT image. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 15/116012 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/12 (20130101) A61B 6/032 (20130101) A61B 6/501 (20130101) A61B 6/5211 (20130101) A61B 6/5235 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36038 (20170801) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00 (20130101) G06K 9/34 (20130101) Original (OR) Class G06K 9/4671 (20130101) G06K 9/6215 (20130101) G06K 2209/051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104195 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey); RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Yingying Chen (Morganville, New Jersey); Jie Yang (Tallahassee, Florida); Yan Wang (Jersey City, New Jersey); Jian Liu (Jersey City, New Jersey); Marco Gruteser (Princeton, New Jersey) |
| ABSTRACT | A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment. |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/074305 |
| ART UNIT | 2472 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/306 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/04 (20130101) H04W 4/027 (20130101) H04W 4/029 (20180201) H04W 84/12 (20130101) H04W 88/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10098337 | Yans |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthew W. Yans (Jacksonville, Florida) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew W. Yans (Jacksonville, Florida) |
| ABSTRACT | The invention relates to a trap for collecting arthropods, for example ticks. The device comprises an attractant placed over an adhesive surface with the adhesive facing down or at an angle to prevent debris from inadvertently collecting. The arthropods, attracted to the device by the attractant then adhere to the adhesive surface on their dorsal side. The invention also relates to a method of using the device to collect insects by placing one or more of the devices in a desired collection area and collecting insects over a period of time without the need for constant monitoring of the devices. |
| FILED | Thursday, September 03, 2015 |
| APPL NO | 14/844170 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/02 (20130101) A01M 1/14 (20130101) Original (OR) Class A01M 1/023 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/34 (20130101) A01N 59/04 (20130101) A01N 59/04 (20130101) Technologies for Adaptation to Climate Change Y02A 50/375 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098414 | Cavanagh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DIAPEDIA, LLC (State College, Pennsylvania); University of Delaware (Newark, Delaware) |
| ASSIGNEE(S) | DIAPEDIA, LLC (State College, Pennsylvania); UNIVERSITY OF DELAWARE (Newark, Delaware) |
| INVENTOR(S) | Peter R. Cavanagh (Seattle, Washington); Timothy B. Hurley (Boalsburg, Pennsylvania); John J. Tierney (Newark, Delaware); John W. Gillespie, Jr. (Hockessin, Delaware) |
| ABSTRACT | The improved footwear system of the present application uses composite materials in the design of an advanced modular in-shoe foot orthosis and a new container assembly which includes a high performance energy storage and return element orthosis. The footwear system uses a method of manufacture incorporating a new last model. The advantages of the footwear system over standard issue combat boots include lower weight, improved treatment of lower extremity overuse injuries and reduction of the occurrence of such overuse injuries by protecting at-risk feet with advanced footwear which can be customized to meet the biomechanical needs as well as the specific activities of the wearer. |
| FILED | Thursday, March 06, 2014 |
| APPL NO | 14/199790 |
| ART UNIT | 3765 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Characteristic Features of Footwear; Parts of Footwear A43B 7/141 (20130101) A43B 7/1445 (20130101) A43B 13/026 (20130101) A43B 13/127 (20130101) A43B 13/141 (20130101) A43B 13/181 (20130101) A43B 13/183 (20130101) A43B 13/386 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098581 | Voldman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Joel Voldman (Belmont, Massachusetts); Hao-Wei Su (Cambridge, Massachusetts); Javier Lopez Prieto (Emeryville, California); Jongyoon Han (Bedford, Massachusetts); Lidan Wu (Cambridge, Massachusetts) |
| ABSTRACT | A system includes a microfluidic device configured to isolate one or more particles from a mixture, a flow rate matching device configured to match flow rate of the microfluidic device with flow rate of an electrical measurement device configured to measure an electrical property of the isolated particles, and an electrical measurement device configured to measure an electrical property of the isolated particles. |
| FILED | Friday, January 16, 2015 |
| APPL NO | 15/111584 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/412 (20130101) Original (OR) Class A61B 5/1468 (20130101) A61B 5/1486 (20130101) A61B 5/14546 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/0605 (20130101) B01L 2200/0647 (20130101) B01L 2200/0652 (20130101) B01L 2300/088 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1031 (20130101) G01N 15/1404 (20130101) G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1484 (20130101) G01N 33/48735 (20130101) G01N 2015/008 (20130101) G01N 2015/0073 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2015/1486 (20130101) G01N 2800/7095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099072 | LeVan, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Martin Douglas LeVan, Jr. (The Villages, Florida); Dushyant Barpaga (Nashville, Tennessee) |
| ABSTRACT | Disclosed are adsorbent materials that comprise a porous material having a continuous silica phase coated with a carbon layer, and a water-insoluble precipitate comprising a metal cation and an anion disposed substantially evenly throughout the adsorbent material. In some examples, the plurality of pores can have an average characteristic dimension of from 0.1 Å to 100 Å. The water-insoluble precipitate can be formed in the plurality of pores of the porous material by contacting the porous material with a first aqueous solution comprising a metal cation; and contacting the porous material with a second aqueous solution comprising an anion; wherein the metal cation and the anion combine to form the water-insoluble precipitate in the plurality of pores of the porous material, thereby forming the adsorbent material. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 15/378128 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/0002 (20130101) A41D 2400/22 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/08 (20130101) A61L 31/022 (20130101) A61L 31/146 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/105 (20130101) A61M 2205/7536 (20130101) Devices, Apparatus or Methods for Life-saving A62B 23/025 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099165 | Walls et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Howard Jerome Walls (Apex, North Carolina); Randall J. Newsome (Apex, North Carolina); Anthony Clint Clayton (Rougemont, North Carolina); Robert W. Yaga (Durham, North Carolina); David Samuel Ensor (Chapel Hill, North Carolina) |
| ABSTRACT | A filtration device including a contoured support having 1) an interior surface, 2) an outside peripheral surface spaced farther from a center of the contoured support than the interior surface, and 3) a rim enclosed and sealed to a perimeter of the contoured support. The filtration device includes macroscopic openings in the contoured support extending from the interior surface to the outside peripheral surface, and a plurality of nanofibers having diameters less than 1 micron. The nanofibers are disposed on the outside peripheral surface of the contoured support, and cover the macroscopic openings to form a filtration medium on the contoured support. |
| FILED | Monday, December 21, 2015 |
| APPL NO | 14/975978 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 18/02 (20130101) A62B 18/04 (20130101) A62B 18/084 (20130101) A62B 23/025 (20130101) Separation B01D 46/0001 (20130101) Original (OR) Class B01D 46/103 (20130101) B01D 46/546 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0076 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2509/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099275 | Propheter-Hinckley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut) |
| ABSTRACT | A component according to an exemplary aspect of the present disclosure includes, among other things, a first cavity, a second cavity and a rib between the first cavity and the second cavity, the rib including a first rib surface that is substantially flat and a second rib surface that is tapered. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 14/670566 |
| ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Foundry Moulding B22C 9/04 (20130101) B22C 9/10 (20130101) Original (OR) Class B22C 9/24 (20130101) B22C 9/103 (20130101) B22C 21/14 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/16 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/232 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/671 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/13 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099322 | Widener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christian Widener (Rapid City, South Dakota); Adam Well (Rapid City, South Dakota); Owen Britton (Rapid City, South Dakota); Brian James (Rapid City, South Dakota); Rob Hrabe (Rapid City, South Dakota); Victor Champagne (Rapid City, South Dakota) |
| ASSIGNEE(S) | South Dakota Board of Regents (Pierre, South Dakota); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Christian Widener (Rapid City, South Dakota); Adam Well (Rapid City, South Dakota); Owen Britton (Rapid City, South Dakota); Brian James (Rapid City, South Dakota); Rob Hrabe (Rapid City, South Dakota); Victor Champagne (Rapid City, South Dakota) |
| ABSTRACT | Methods for aircraft component repair and reclamation are provided. Cold spraying aircraft panels include identifying a fastener hole in an aircraft panel in need of repair, capturing the location of the fastener hole, and depositing cold spray material about the fastener hole for reclaiming the aircraft panel. Any excess material may be removed. Cold spraying hydraulic lines includes identifying a surface of the hydraulic line in need of repair, aiming a cold spray nozzle at the surface of the hydraulic line and depositing a cold spray material on the surface of the hydraulic line. Excess cold spray material may be removed as needed. |
| FILED | Tuesday, October 29, 2013 |
| APPL NO | 14/066443 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/16 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/00 (20130101) Original (OR) Class Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/40 (20170101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49718 (20150115) Y10T 29/49723 (20150115) Y10T 29/49746 (20150115) Y10T 29/49748 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099417 | Mott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David R. Mott (Burke, Virginia); Frances S. Ligler (Fuquay Varina, North Carolina); Stephanie Fertig (Springfield, Virginia); Aron Bobrowski (Miami, Florida) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David R. Mott (Burke, Virginia); Peter B. Howell, Jr. (Gaithersburg, Maryland); Frances S. Ligler (Fuquay Varina, North Carolina); Stephanie Fertig (Springfield, Virginia); Aron Bobrowski (Miami, Florida) |
| ABSTRACT | A sheath flow system having a channel with at least one fluid transporting structure located in the top and bottom surfaces situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. The design can be readily incorporated into microfluidic chips without the need for special manufacturing protocols. Uses include extruding materials and/or fabricating structures. |
| FILED | Wednesday, August 12, 2015 |
| APPL NO | 14/824635 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502746 (20130101) B01L 3/502776 (20130101) B01L 2400/084 (20130101) B01L 2400/0487 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0014 (20130101) B29C 47/30 (20130101) B29C 47/065 (20130101) Original (OR) Class B29C 47/0816 (20130101) Optical Elements, Systems, or Apparatus G02B 6/032 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49 (20150115) Y10T 137/0318 (20150401) Y10T 137/0324 (20150401) Y10T 137/0329 (20150401) Y10T 137/0335 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099644 | Debevec et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul E. Debevec (Culver City, California); Mark Bolas (Los Angeles, California); Graham L. Fyffe (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Paul E. Debevec (Culver City, California); Mark Bolas (Los Angeles, California); Graham L. Fyffe (Los Angeles, California) |
| ABSTRACT | A facial image capture system may capture images of a face of a person while the person is moving. A video camera may capture sequential images of a scene to which the video camera is directed. A marker-based location detection system may determine and generate information about the location of a marker worn on or close to the face of the person. A camera control system may automatically adjusts both the horizontal and vertical direction to which the video camera is directed so as to cause the sequential images of the camera to each be of the face of the person while the person is moving, based on the information about the location of the marker from the marker-based location detection system. |
| FILED | Wednesday, May 27, 2015 |
| APPL NO | 14/723066 |
| ART UNIT | 2483 — Recording and Compression |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/26 (20130101) B29C 45/1657 (20130101) B29C 45/14065 (20130101) B29C 45/14508 (20130101) B29C 2045/1454 (20130101) B29C 2045/1664 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) B29K 2105/04 (20130101) B29K 2105/256 (20130101) B29K 2623/12 (20130101) B29K 2623/0608 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2009/00 (20130101) B29L 2031/3008 (20130101) B29L 2031/3038 (20130101) Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 13/0256 (20130101) B60R 21/205 (20130101) B60R 21/215 (20130101) B60R 21/2165 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/7864 (20130101) Pictorial Communication, e.g Television H04N 5/247 (20130101) H04N 5/23219 (20130101) H04N 5/23261 (20130101) H04N 5/23296 (20130101) H04N 7/181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099799 | Hughes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Truman Hughes (Silex, Missouri); Glenn E. Stinson (Collingswood, New Jersey) |
| ABSTRACT | A boom nozzle assembly for use with an aerial refueling boom on an aerial refueling aircraft where a shielded wiring cable from the aerial refueling boom is connected to an articulated boom nozzle through an electrical connection on the wear ring of the articulated boom nozzle and then routed to a solenoid and other devices of the articulated boom nozzle without passing through the universal joint area of the articulated boom nozzle. The boom nozzle assembly may include a torsion cable reel that keeps the shielded wiring cable in tension as the articulated boom nozzle changes its position relative to the boom nozzle assembly. The torsion cable reel may be positioned within a cable reel housing attached at the aft end of the aerial refueling boom. |
| FILED | Tuesday, September 15, 2015 |
| APPL NO | 14/855148 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 39/06 (20130101) Original (OR) Class Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 75/486 (20130101) B65H 2701/34 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 11/1033 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/60 (20130101) H01R 24/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099918 | Helvajian |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Henry Helvajian (Pasadena, California) |
| ABSTRACT | A photostructurable ceramic is processed using photostructuring process steps for embedding devices within a photostructurable ceramic volume, the devices may include one or more of chemical, mechanical, electronic, electromagnetic, optical, and acoustic devices, all made in part by creating device material within the ceramic or by disposing a device material through surface ports of the ceramic volume, with the devices being interconnected using internal connections and surface interfaces. |
| FILED | Wednesday, June 22, 2016 |
| APPL NO | 15/189792 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 2219/00788 (20130101) B01J 2219/00835 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502738 (20130101) B01L 2300/12 (20130101) B01L 2300/0654 (20130101) B01L 2300/0874 (20130101) B01L 2400/0439 (20130101) B01L 2400/0478 (20130101) B01L 2400/0633 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/051 (20130101) B81B 2203/0338 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00341 (20130101) Original (OR) Class B81C 1/00634 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/00 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 55/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/70216 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099920 | Shen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jie Shen (Worcester, Massachusetts); Wei Sun (Brookline, Massachusetts); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | The present disclosure relates to the alignment of moieties (e.g., nanoparticles and/or nanowires) into prescribed architectures on two- and/or three-dimensional substrates (e.g., nucleic acid nanostructures/crystals). The present disclosure also relates to a nucleic acid (e.g., DNA) lithography method that includes, in some embodiments, adsorbing a bare nucleic acid nanostructure onto a surface of a substrate, and etching the surface of the substrate containing the bare nucleic acid nanostructure, thereby producing a patterned substrate. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 15/312854 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00659 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0047 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099928 | Tse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Stephen D. Tse (Warren, New Jersey); Nasir K. Memon (Piscataway, New Jersey); Bernard H. Kear (Whitehouse Station, New Jersey) |
| ABSTRACT | Apparatus and methods of use thereof for the production of carbon-based and other nanostructures, as well as fuels and reformed products, are provided. |
| FILED | Thursday, May 12, 2016 |
| APPL NO | 15/152920 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/323 (20130101) C01B 3/363 (20130101) C01B 31/0293 (20130101) Original (OR) Class C01B 2203/0255 (20130101) C01B 2203/1223 (20130101) C01B 2203/1241 (20130101) C01B 2203/1247 (20130101) Burners F23D 14/22 (20130101) F23D 14/32 (20130101) F23D 14/56 (20130101) F23D 14/58 (20130101) F23D 14/78 (20130101) F23D 14/84 (20130101) F23D 91/02 (20150701) F23D 2900/00001 (20130101) F23D 2900/21007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099967 | McCrary et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| ASSIGNEE(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| INVENTOR(S) | Parker D. McCrary (Tuscaloosa, Alabama); Robin D. Rogers (Tuscaloosa, Alabama) |
| ABSTRACT | Disclosed are hypergolic salts with borane cluster anions that ignite spontaneously upon contact with nitric acid (from 70% to 100% in water) with short ignition delay. The salts, when added as trigger additive to combustible solvent or ionic liquids, make the resulting formulation hypergolic. The salts with borane cluster anions also shorten ignition delay in hypergols, such as RP-1, and additionally allow nitric acid to be used to replace liquid oxygen as an oxidizer. In some examples, the borane salts are formed in situ in an ionic liquid. |
| FILED | Friday, June 20, 2014 |
| APPL NO | 14/310375 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 43/00 (20130101) Original (OR) Class C06B 47/10 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/542 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100093 | Tam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EPITOPIX LLC (Willmar, Minnesota) |
| ASSIGNEE(S) | EPITOPIX LLC (Willmar, Minnesota) |
| INVENTOR(S) | Patricia Tam (Golden Valley, Minnesota); Lisa L. Herron-Olson (Minneapolis, Minnesota); Drew M. Catron (Shoreview, Minnesota) |
| ABSTRACT | This disclosure provides isolated polypeptides isolatable from a Burkholderia spp., compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. This disclosure also provides antibody that specifically binds one or more of the polypeptides isolatable from a Burkholderia spp, compositions that include such antibody, and methods for using such antibody. |
| FILED | Tuesday, December 30, 2014 |
| APPL NO | 14/586157 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/104 (20130101) A61K 2039/70 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/195 (20130101) Original (OR) Class C07K 16/1203 (20130101) C07K 2317/33 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100335 | Prather et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kristala Lanett Jones Prather (Milton, Massachusetts); Micah James Sheppard (Arlington, Massachusetts); Aditya Kunjapur (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to recombinant cells and their use in in the production of branched medium-chain alcohols such as 4-methyl-1-pentanol. |
| FILED | Friday, October 31, 2014 |
| APPL NO | 14/530540 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/88 (20130101) C12N 9/2402 (20130101) C12N 15/09 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100402 | Bol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ageeth A. Bol (Yorktown Heights, New York); Xuesong Li (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ageeth A. Bol (Yorktown Heights, New York); Xuesong Li (Yorktown Heights, New York) |
| ABSTRACT | An apparatus and method for graphene film synthesis. The apparatus includes a quasi enclosed substrate holder which includes one open side, a cap disposed over the one open side of the quasi enclosed substrate holder, and a substrate for graphene film synthesis located inside the quasi enclosed substrate holder. The method includes placing a substrate for graphene film synthesis inside of a quasi enclosed substrate holder and generating a graphene film on the substrate via chemical vapor deposition, wherein the quasi enclosed substrate holder includes one open side and a cap disposed over the open side of the quasi enclosed substrate holder. |
| FILED | Friday, October 07, 2011 |
| APPL NO | 13/269037 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/186 (20170801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Original (OR) Class C23C 16/4582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100646 | Propheter-Hinckley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut); Steven Bruce Gautschi (Naugatuck, Connecticut); San Quach (East Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut); Steven Bruce Gautschi (Naugatuck, Connecticut); San Quach (East Hartford, Connecticut) |
| ABSTRACT | A component for a gas turbine engine according to an exemplary aspect of the present disclosure includes, among other things, a body portion, a cooling circuit disposed within the body portion and including at least a first cavity and a microcircuit in fluid communication with the first cavity. A plunged hole intersects at least a portion of the microcircuit. |
| FILED | Friday, August 03, 2012 |
| APPL NO | 13/565877 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Foundry Moulding B22C 9/04 (20130101) B22C 9/10 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/02 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/14 (20130101) F05D 2230/211 (20130101) F05D 2260/204 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 7/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49234 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100657 | Chuong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Conway Chuong (Manchester, Connecticut) |
| ABSTRACT | An assembly includes a monolithic carrier structure and a seal assembly. The monolithic carrier structure includes a carrier base and a support ring. The carrier base extends axially along the centerline. The support ring projects radially inward from the carrier base. The seal assembly is nested radially within the carrier base and axially next to the support ring. The seal assembly includes a seal base, a plurality of spring elements and a plurality of seal shoes arranged about the centerline in an annular array. The seal base circumscribes the annular array of the seal shoes. Each of the spring elements is radially between and connects a respective one of the seal shoes with the seal base. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/236855 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/02 (20130101) F01D 11/04 (20130101) Original (OR) Class F01D 25/24 (20130101) F01D 25/162 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) Pistons; Cylinders; Sealings F16J 15/40 (20130101) F16J 15/3268 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100667 | Swift et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Anthony B. Swift (North Waterboro, Maine); Paul M. Lutjen (Kennebunkport, Maine); Neil L. Tatman (Brentwood, New Hampshire); Dominic J. Mongillo, Jr. (West Hartford, Connecticut); Matthew A. Devore (Rocky Hill, Connecticut); Ken F. Blaney (Middleton, New Hampshire) |
| ABSTRACT | A gas turbine engine component is provided. The gas turbine engine component comprises a main body and a leading edge cooling passage defined within the main body. The main body has a leading edge and a leading edge wall including an elongated transition portion extending between the leading edge and a proximate flowpath surface of the main body. The leading edge cooling passage comprises an axial flow cooling passage defined within the main body and adjacent to the leading edge wall and has a leading edge periphery that generally conforms to the elongated transition portion of the leading edge wall. |
| FILED | Friday, January 15, 2016 |
| APPL NO | 14/997315 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/08 (20130101) F01D 25/12 (20130101) Original (OR) Class F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/11 (20130101) F05D 2240/81 (20130101) F05D 2260/202 (20130101) F05D 2260/204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100705 | Ilic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| ASSIGNEE(S) | SIKORSKY AIRCRAFT CORPORATION (Stratford, Connecticut) |
| INVENTOR(S) | Vladimir Ilic (Orange, Connecticut); Donald William Lamb, Jr. (North Haven, Connecticut) |
| ABSTRACT | An exhaust mixer includes, a plurality of outwardly oriented vanes having planar surfaces, and a plurality of inwardly oriented vanes alternately positioned perimetrically between the plurality of outwardly oriented vanes, and a core flow area defined inwardly of inner most portions of the plurality of inwardly oriented vanes, the exhaust mixer being configured such that a minority of the total flow through the exhaust mixer travels through the core flow area when the exhaust mixer is employed during a mixing operation. |
| FILED | Friday, June 26, 2015 |
| APPL NO | 14/751667 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/0616 (20130101) B01F 2005/0639 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 13/002 (20130101) F01N 13/082 (20130101) Original (OR) Class F01N 2240/20 (20130101) Jet-propulsion Plants F02K 1/48 (20130101) F02K 1/825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100740 | Thomas |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Michael R. Thomas (Bloomfield, Connecticut) |
| ABSTRACT | A plate/fin heat exchanger includes multiple stacked panels defining a curvature. Each of the panels has a first corrugated sheet defining a first set of passages and a second corrugated sheet defining a second set of passages. Each of the corrugated sheets includes multiple aligned corrugations, and the corrugations of the first corrugated sheet are not aligned with the corrugations of the second corrugated sheet. Each of the corrugations has a corrugation height defined as a length of said corrugation tangential to a curvature of the plate/fin heat exchanger, and wherein each of the first corrugated sheets includes axially aligned corrugations defining a wedge shaped radial cross section. |
| FILED | Friday, June 13, 2014 |
| APPL NO | 14/897138 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/185 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/115 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/61 (20130101) F05D 2250/71 (20130101) F05D 2260/213 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/0358 (20130101) F28D 9/02 (20130101) F28D 9/0025 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/02 (20130101) F28F 3/025 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100779 | Alholm et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Hannes A. Alholm (Tolland, Connecticut); Joseph J. Czapski, Jr. (New Britain, Connecticut); Bessem Jlidi (Rocky Hill, Connecticut); Alex J. Simpson (Tolland, Connecticut) |
| ABSTRACT | A drive link assembly includes a case having a spherically formed inner ring. A clevis is affixed to a surface of the case such that is disposed horizontally between a first end and a second end of the clevis. A spacer having a spherical inset portion is positioned on the surface horizontally between the clevis and the spherically formed inner ring, such that the spherical inset portion is aligned with the spherically formed inner ring. A spherical bearing is seated within the spherically formed inner ring. A rod is affixed to an outer surface of the spherical bearing. |
| FILED | Saturday, April 09, 2016 |
| APPL NO | 15/095041 |
| ART UNIT | 3656 — Material and Article Handling |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/003 (20130101) Aeroplanes; Helicopters B64C 15/00 (20130101) Jet-propulsion Plants F02K 1/15 (20130101) F02K 1/1292 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/40 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 23/043 (20130101) F16C 23/045 (20130101) F16C 2360/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101031 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Alexander W. Williams (Windsor Locks, Connecticut); Seth A. Max (Manchester, Connecticut); Christopher B. Lyons (West Hartford, Connecticut) |
| ABSTRACT | A swirler for a combustor of a gas turbine engine includes a swirler outer body with a male snap component and/or female snap component of a snap-fit interface defined around a swirler central longitudinal axis. A bulkhead assembly for a combustor of a gas turbine engine includes a swirler mounted to a bulkhead support shell through a snap-fit interface. |
| FILED | Monday, June 30, 2014 |
| APPL NO | 14/911205 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/12 (20130101) Original (OR) Class F23R 3/14 (20130101) F23R 3/60 (20130101) F23R 3/286 (20130101) F23R 2900/00017 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101106 | Walton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Cody L. Walton (Springville, Indiana); Todd H. Heuer (Peyton, Colorado) |
| ABSTRACT | Various systems and related methods are provided including various carrier and feed systems that feed belts of consumable items to consuming systems. Exemplary systems relate to on-demand high capacity and speed portable part or consumable item carrier and belt feed system that reduces or eliminates jams or mis-feeds to include jams or mis-feeds due to tilting of belt linked consumable items. Some embodiments also permit consumable items to be carried in an exemplary carrier with removable dividers that create cavities to dispose a series of columns of sequentially folded belt sections extended to a top of the removable dividers that further enable a second belt fold configuration of the belt of consumable items to be folded across the columns of folded belt sections and then oriented to be pulled out of the carrier for use with a consuming system coupled with the carrier. |
| FILED | Wednesday, September 20, 2017 |
| APPL NO | 15/710542 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 9/79 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101125 | Conklin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Wasington, District of Columbia) |
| INVENTOR(S) | Scott A. Conklin (Fort Branch, Indiana) |
| ABSTRACT | A system and method having a first device mounted on a first gimbal mount; a first visual feedback associated with the first gimbal; a second device mounted on a second gimbal mount physically displaced relative to the first gimbal mount; a second visual feedback mechanism associated with the second device. The orientation of the first device differs from the orientation of the second device by a dynamic correction amount. A correction controller having input that when acted upon by a user causes movement of the second device independently of movement of the first device to alter the correction amount to a revised correction amount such that subsequent movement of the first device causes motion in the second device that is at least partially dependent upon the revised correction amount. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/395741 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Weapon Sights; Aiming F41G 3/165 (20130101) F41G 3/323 (20130101) F41G 5/14 (20130101) Original (OR) Class F41G 5/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101139 | Hardt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lee R. Hardt (Ridgecrest, California); Donald L. Burnett (Ridgecrest, California); Josiah S. Garfield (Ridgecrest, California); Robert A. Koontz (Anchorage, Alaska) |
| ABSTRACT | Embodiments of the invention are directed to enhancing insensitive munitions performance. Some embodiments of the invention employ an outgassing pad having unique geometrical configurations and positioning. Other embodiments rely on using thermally-releasable components to foster billet expulsion. Additional embodiments combine both aspects into an entire cook-off mitigation system. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/380679 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/20 (20130101) F42B 12/22 (20130101) F42B 12/207 (20130101) Original (OR) Class F42B 39/14 (20130101) F42B 39/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101212 | Cleary et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Justin W Cleary (Miamisburg, Ohio); Robert E Peale (Winter Park, Florida); Evan Smith (Dayton, Ohio); Janardan Nath (Orlando, Florida) |
| ABSTRACT | A wavelength selective bolometer includes a substrate configured to serve as a foundation for the apparatus and a thermal isolation gap established between the substrate and subsequent solid material layers. A conducting ground plane layer is disposed above the thermal isolation gap, and a first dielectric layer is mated to a top surface of the conducting ground plane. A temperature sensing material layer is mated to a top surface of the first dielectric layer, and a plurality of interconnects is placed in electrical communication with the temperature sensing material layer. A second dielectric layer is mated to a top surface of the temperature sensing material, and at least one conductive element is mated to a top surface of the second dielectric layer. The dimensions of the conductive element and other variables are chosen to achieve resonant absorption of selected wavelengths of radiation incident thereupon. |
| FILED | Monday, March 13, 2017 |
| APPL NO | 15/457442 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/02 (20130101) G01J 5/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101273 | Ja |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FLIR Detection, Inc. (Wilsonville, Oregon) |
| ASSIGNEE(S) | FLIR Detection, Inc. (Wilsonville, Oregon) |
| INVENTOR(S) | Shiou-jyh Ja (Stillwater, Oklahoma) |
| ABSTRACT | This invention generally relates to optical devices that can collect and detect signal emissions effectively while allowing the excitation light path and the sample flow path to coexist non-obstructively in a compact format. The device has various embodiments, such as an embodiment including a plurality of reporters disposed on a sensing surface, wherein each one of the plurality of reporters is configured to react with a least one target analyte, a hyperspectral detection module configured to capture hyperspectral image data corresponding to the plurality of reporters, and a controller. The controller is configured to receive the hyperspectral image data from the hyperspectral detection module and generate a temporal spectral signature corresponding to each one of the plurality of reporters from the received hyperspectral image data. |
| FILED | Friday, August 07, 2015 |
| APPL NO | 14/821553 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/643 (20130101) G01N 21/645 (20130101) G01N 21/648 (20130101) Original (OR) Class G01N 21/6428 (20130101) G01N 33/227 (20130101) G01N 2021/6423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101293 | Gupta |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (Palo Alto, California) |
| INVENTOR(S) | Chaitanya Gupta (Foster City, California) |
| ABSTRACT | Aspects of a biosensor platform system and method are described. In one embodiment, the biosensor platform system includes a fluidic system and tunneling biosensor interface coupled to the fluidic system. The tunneling biosensor interface may include a transducing electrode array having at least one dielectric thin film deposited on an electrode array. The biosensor platform system may further include processing logic operatively coupled to the transducing electrode array. In operation, the application of an electromagnetic field at an interface between an electrode and an electrolyte in the system, for example, may result in the transfer of charge across the interface. The transfer of charge is, in turn, characterized by electromagnetic field-mediated tunneling of electrons that may be assisted by exchange of energy with thermal vibrations at the interface. By analysis of the transfer of charge, the identify of various analytes, for example, or other compositions. |
| FILED | Friday, August 08, 2014 |
| APPL NO | 14/455205 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101339 | Dresios et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
| ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
| INVENTOR(S) | John Dresios (Carlsbad, California); Richard Griffey (Vista, California) |
| ABSTRACT | The present disclosure relates to methods for identifying proteins or peptide motifs of intracellular, extracellular, or extracellular matrix proteins specifically exposed in wound sites, as well as compositions for treating wounds, and methods for their use. |
| FILED | Friday, June 24, 2016 |
| APPL NO | 15/191632 |
| ART UNIT | 1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 38/02 (20130101) A61K 38/1777 (20130101) A61K 39/44 (20130101) A61K 47/42 (20130101) A61K 47/6801 (20170801) A61K 47/6803 (20170801) A61K 47/6811 (20170801) A61K 47/6847 (20170801) A61K 49/0058 (20130101) Peptides C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/567 (20130101) G01N 33/5088 (20130101) G01N 33/6887 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2333/47 (20130101) G01N 2333/78 (20130101) G01N 2333/4712 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101436 | Martone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory ATTN: RDRL-LOC-1 (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Anthony F. Martone (Ellicott City, Maryland); Kenneth I. Ranney (Rockville, Maryland); Traian V. Dogaru (Ellicott City, Maryland); Kelly D. Sherbondy (Burke, Virginia) |
| ABSTRACT | A method for optimizing bandwidth selection of a radar transmission in a frequency bandwidth in which the frequency bandwidth is divided into a plurality of sub-bands having a plurality of different bandwidths. The energy level is measured for each sub-band and a range resolution is also determined for each sub-band. Thereafter, a sub-band is selected in the frequency range where the signal to interference plus noise ratio plus the range resolution is maximum. Thereafter, a radar transmission is transmitted in the selected sub-band with a bandwidth corresponding to the bandwidth of the selected sub-band. |
| FILED | Tuesday, August 11, 2015 |
| APPL NO | 14/822949 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/023 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0062 (20130101) Wireless Communication Networks H04W 16/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101786 | Eastep et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jonathan M. Eastep (Portland, Oregon); Richard J. Greco (West Linn, Oregon) |
| ABSTRACT | Methods and apparatus to provide holistic global performance and power management are described. In an embodiment, logic (e.g., coupled to each compute node of a plurality of compute nodes) causes determination of a policy for power and performance management across the plurality of compute nodes. The policy is coordinated across the plurality of compute nodes to manage a job to one or more objective functions, where the job includes a plurality of tasks that are to run concurrently on the plurality of compute nodes. Other embodiments are also disclosed and claimed. |
| FILED | Monday, December 22, 2014 |
| APPL NO | 14/580150 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 1/189 (20130101) G06F 1/3203 (20130101) Original (OR) Class G06F 9/4893 (20130101) G06F 9/5094 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102032 | Howe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Benjamin M. Howe (Plano, Texas); Jacob L. Sanders (Wylie, Texas) |
| ABSTRACT | Embodiments relate to facilitating quick and graceful transitions for massively parallel computing applications. A computer-implemented method for facilitating termination of a plurality of threads of a process is provided. The method maintains information about open communications between one or more of the threads of the process and one or more of other processes. In response to receiving a command to terminate one or more of the threads of the process, the method completes the open communications on behalf of the threads after terminating the threads. |
| FILED | Thursday, May 29, 2014 |
| APPL NO | 14/289852 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/485 (20130101) G06F 9/4881 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102090 | Jenkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Keith A. Jenkins (Sleepy Hollow, New York); Barry P. Linder (Hastings-on-Hudson, New York); Emily A. Ray (Hastings on Hudson, New York); Raphael P. Robertazzi (Ossining, New York); Peilin Song (Lagrangeville, New York); James H. Stathis (Poughquag, New York); Kevin G. Stawiasz (Bethel, Connecticut); Franco Stellari (Waldwick, New Jersey); Alan J. Weger (Mohegan Lake, New York); Emmanuel Yashchin (Yorktown Heights, New York) |
| ABSTRACT | A method and system are provided for chip testing. The method includes ascertaining a baseline for a functioning chip with no stress history by performing a non-destructive test procedure on the functioning chip. The method further includes repeating the test procedure on a chip under test using a threshold derived from the baseline as a reference point to determine a stress history of the chip under test. The test procedure includes ordering each of a plurality of functional patterns by a respective minimum operating period corresponding thereto, ranking each pattern based on at least one preceding available pattern to provide a plurality of pattern ranks, and calculating a sum by summing the pattern ranks. The sum calculated by the ascertaining step is designated as the baseline, and the sum calculated by the repeating step is compared to the threshold to determine the stress history of the chip under test. |
| FILED | Monday, May 16, 2016 |
| APPL NO | 15/156136 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/263 (20130101) G06F 11/2236 (20130101) G06F 11/2273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102110 | Kimball et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John D. Kimball (Fredericksburg, Virginia); James Alan Thomas (King George, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John D. Kimball (Fredericksburg, Virginia); James Alan Thomas (King George, Virginia) |
| ABSTRACT | An interface behavior simulator communications processor is provided for operating on a non-transitory computer platform for analyzing and sending a message between first and second components via a network. The adapter system includes a middleware provider, an elements loader, a connections loader, an elements finalizer, a message type identifier, a message broker, a brokering transmitter, a brokering initializer and a message reactor. The middleware provider transports the message over the network. The elements loader accesses a plurality of instruction elements, the including initializing, receiving, forking, joining, message mapping, filtering, publishing, activity diagramming and finalizing. The connections loader connects a first instruction element to a second instruction element in an action configuration. The elements finalizer locks the action configuration. The identifier determines a message type of an activity diagram element, in which the message types access the instruction elements for receiving and publishing. The message broker provides a communication protocol for the message. The brokering transmitter connects the instruction element for publishing to the message broker to produce a publishing interface element. The brokering initializer initializes the message broker. The message reactor executes a message instruction in reaction to the message. |
| FILED | Thursday, June 09, 2016 |
| APPL NO | 15/178276 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0486 (20130101) G06F 8/38 (20130101) G06F 11/3672 (20130101) Original (OR) Class G06F 17/5009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102124 | Steely, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Simon C. Steely, Jr. (Hudson, New Hampshire); William C. Hasenplaugh (Boston, Massachusetts); Joel S. Emer (Hudson, Massachusetts); Samantika Subramaniam (Westford, Massachusetts) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Simon C. Steely, Jr. (Hudson, New Hampshire); William C. Hasenplaugh (Boston, Massachusetts); Joel S. Emer (Hudson, Massachusetts); Samantika Subramaniam (Westford, Massachusetts) |
| ABSTRACT | A micro-architecture may provide a hardware and software of a high bandwidth write command. The micro-architecture may invoke a method to perform the high bandwidth write command. The method may comprise sending a write request from a requester to a record keeping structure. The write request may have a memory address of a memory that stores requested data. The method may further determine copies of the requested data being present in a distributed cache system outside the memory, sending invalidation requests to elements holding copies of the requested data in the distributed cache system, sending a notification to the requester to inform presence of copies of the requested data and sending a write response message after a latest value of the requested data and all invalidation acknowledgements have been received. |
| FILED | Wednesday, December 28, 2011 |
| APPL NO | 13/993716 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0808 (20130101) Original (OR) Class G06F 13/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102317 | Reinhardt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Colin Norris Reinhardt (San Diego, California) |
| ABSTRACT | A method comprising the step of partitioning a 3D model domain into disjoint subsets of interaction and propagation subdomain volumes, wherein propagator methods transport plenoptic field through extents of volumetric media between interaction subdomain boundaries, wherein distinct interaction methods are applied to each interaction subdomain separately and govern the solution process within the subdomain and field-exchange at boundary. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/469100 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/225 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102390 | Cordella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas Cordella (Tampa, Florida); John Profumo (St. Petersburg, Florida) |
| ASSIGNEE(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| INVENTOR(S) | Thomas Cordella (Tampa, Florida); John Profumo (St. Petersburg, Florida) |
| ABSTRACT | Contents of a memory may be authenticated using redundant encryption. In some examples, data to be stored by a memory is encrypted with two unique encryption keys—a first encryption key is used generate a cipher text and a second encryption key (different than the first encryption key) is used to generate an authentication tag. The cipher text and authentication tag are stored by the memory. At a later time, the cipher text and authentication tag may be retrieved from the memory and decrypted using the respective encryption keys. After decrypting the cipher text and the authentication tag, the data retrieved from the memory may be authenticated by comparing the plaintext generated by decrypting the cipher text and with the plaintext generated by decrypting the authentication tag. A match between the plaintext indicates the data was not corrupted or modified during storage in the memory. |
| FILED | Thursday, June 28, 2012 |
| APPL NO | 13/536653 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 12/1408 (20130101) G06F 21/64 (20130101) G06F 21/6209 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102474 | Alvarez-Icaza Rivera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Rodrigo Alvarez-Icaza Rivera (San Jose, California); John V. Arthur (Mountain View, California); Andrew S. Cassidy (San Jose, California); Bryan L. Jackson (Fremont, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California); Jun Sawada (Austin, Texas) |
| ABSTRACT | The present invention provides a system comprising multiple core circuits. Each core circuit comprises multiple electronic axons for receiving event packets, multiple electronic neurons for generating event packets, and a fanout crossbar including multiple electronic synapse devices for interconnecting the neurons with the axons. The system further comprises a routing system for routing event packets between the core circuits. The routing system virtually connects each neuron with one or more programmable target axons for the neuron by routing each event packet generated by the neuron to the target axons. Each target axon for each neuron of each core circuit is an axon located on the same core circuit as, or a different core circuit than, the neuron. |
| FILED | Friday, March 28, 2014 |
| APPL NO | 14/229756 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102902 | Burnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Randall M. Burnett (Catonsville, Maryland); Quentin P. Herr (Ellicott City, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Randall M. Burnett (Catonsville, Maryland); Quentin P. Herr (Ellicott City, Maryland) |
| ABSTRACT | One embodiment includes a superconducting gate memory circuit. The circuit includes a Josephson D-gate circuit configured to set a digital state as one of a first data state and a second data state in response to a write enable single flux quantum (SFQ) pulse provided on a write enable input and a respective presence of or absence of a write data SFQ pulse provided on a data write input. The circuit also includes a storage loop coupled to the Josephson D-gate. The storage loop can be configured to store the digital state and to readout the digital state at an output in response to a read enable SFQ pulse provided on a read enable input and a read data SFQ pulse provided on a read data input. |
| FILED | Monday, September 25, 2017 |
| APPL NO | 15/714698 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/44 (20130101) Original (OR) Class Pulse Technique H03K 3/38 (20130101) H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103230 | Van Brunt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cree, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Edward Robert Van Brunt (Morrisville, North Carolina); Alexander V. Suvorov (Durham, North Carolina); Vipindas Pala (Durham, North Carolina); Lin Cheng (Chapel Hill, North Carolina) |
| ABSTRACT | A semiconductor device structure according to some embodiments includes a silicon carbide substrate having a first conductivity type, a silicon carbide drift layer having the first conductivity type on the silicon carbide substrate and having an upper surface opposite the silicon carbide substrate, and a buried junction structure in the silicon carbide drift layer. The buried junction structure has a second conductivity type opposite the first conductivity type and has a junction depth that is greater than about one micron. |
| FILED | Monday, October 31, 2016 |
| APPL NO | 15/339178 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/046 (20130101) H01L 21/047 (20130101) H01L 21/324 (20130101) H01L 21/26506 (20130101) H01L 21/26586 (20130101) H01L 29/0619 (20130101) H01L 29/0688 (20130101) H01L 29/861 (20130101) H01L 29/872 (20130101) H01L 29/0878 (20130101) H01L 29/1095 (20130101) H01L 29/1608 (20130101) Original (OR) Class H01L 29/6606 (20130101) H01L 29/7802 (20130101) H01L 29/7828 (20130101) H01L 29/66068 (20130101) H01L 29/66712 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103441 | Legare |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | David J. Legare (Ava, New York) |
| ABSTRACT | Antenna system being tunable over multiple frequency bands. One planar surface of the antenna structure has metallic radiating elements of various geometries with selectable electrical interconnections between the radiating elements. An opposite side of the antenna structure has a signal transmission network with signal feedthroughs to selected metallic radiating elements. The signal transmission network also has phase shift inducing means. Depending on the frequency band of operation, metallic radiating elements are appropriately combined through the electrical interconnections to form composite radiating elements with resonant frequencies within the frequency band of operation. Induced phase shifts in the signal paths feeding selected metallic radiating elements cause a net resultant free-space directivity gain. |
| FILED | Monday, May 09, 2016 |
| APPL NO | 15/149215 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/26 (20130101) H01Q 3/30 (20130101) H01Q 5/30 (20150115) H01Q 5/357 (20150115) H01Q 9/0442 (20130101) Original (OR) Class H01Q 9/0485 (20130101) H01Q 21/065 (20130101) H01Q 25/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103890 | Lu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Haw-minn Lu (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haw-minn Lu (San Diego, California) |
| ABSTRACT | Disclosed is a method of evaluating membership in a membership set. The membership query system receives data to determine membership. A representative pattern is extracted from the data that may be of a predetermined length or of an arbitrary length. A learning mode of the membership query system defines the membership set as a membership signature. The membership query system then determines whether the representative pattern is a member of the membership signature by applying a membership function. In the context of cybersecurity, if the data is a member of a set of known good executable files, then the executable file may be allowed or installed. If the data is not a member of a set of known good executable files, then the file is flagged for further investigation. |
| FILED | Monday, August 10, 2015 |
| APPL NO | 14/822843 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) Original (OR) Class H04L 63/123 (20130101) H04L 63/0861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103913 | Pande et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Partha Pande (Pullman, Washington); Deukhyoun Heo (Pullman, Washington) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington) |
| INVENTOR(S) | Partha Pande (Pullman, Washington); Deukhyoun Heo (Pullman, Washington) |
| ABSTRACT | In some embodiments, improved routing strategies for small-world network-on-chip (SWNoC) systems are provided. In some embodiments, an ALASH routing strategy or an MROOTS strategy are used in order to improve latency, temperature, and energy use within a network-on-chip system. In some embodiments, millimeter-wave wireless transceivers are used to implement the long-distance links within the small-world network, to create a millimeter-wave small-world network-on-chip (mSWNoC) system. In some embodiments, non-coherent on-off keying (OOK) wireless transceivers are used to implement the wireless links. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/081524 |
| ART UNIT | 2411 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 1/40 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0331 (20130101) H04L 7/0337 (20130101) H04L 27/0002 (20130101) Original (OR) Class H04L 27/04 (20130101) H04L 27/06 (20130101) H04L 45/12 (20130101) H04L 47/30 (20130101) H04L 49/60 (20130101) H04L 49/109 (20130101) H04L 2012/6421 (20130101) Wireless Communication Networks H04W 40/02 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 70/00 (20180101) Y02D 70/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104096 | Collins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | James C Collins (Mico, Texas); Chet M Wall (San Antonio, Texas); Robert J Kaufman, III (San Antonio, Texas) |
| ABSTRACT | An Enhanced Ethernet Network Interface Card (EENIC) interfaces with a host and a network. The EENIC includes an internal network interface controller (NIC), a field programmable array (FPGA) in electrical communication with the internal network interface controller, and a peripheral component interconnect express (PCIe) controller, in independent electrical communication with the field programmable array or the internal network interface controller. The FPGA is configured to intercept data from either the host, or from the network, or from a combination thereof. Additionally, the configured interception is undetected by the host, or by the network, or a combination thereof. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 15/612343 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/0209 (20130101) H04L 63/0876 (20130101) H04L 63/1408 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104555 | Dain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shared Spectrum Company (Vienna, Virginia) |
| ASSIGNEE(S) | Shared Spectrum Company (Vienna, Virginia) |
| INVENTOR(S) | Dmitry Dain (Herndon, Virginia); Igor Bazarov (Herndon, Virginia); Eugene Livis (Vienna, Virginia); Mark Allen McHenry (McLean, Virginia) |
| ABSTRACT | Systems and methods for configuring a network of radios for dynamic spectrum access are described. A network radio can include hardware and/or software modules for detecting a radio environment and negotiating common communications channels with a plurality of other radios in the network. Network radio behavior can be defined by a plurality of predefined policies which are used in combination with the information about the radio environment to select common operating parameters. |
| FILED | Monday, June 16, 2014 |
| APPL NO | 14/305159 |
| ART UNIT | 2462 — Multiplex and VoIP |
| CURRENT CPC | Wireless Communication Networks H04W 16/14 (20130101) Original (OR) Class H04W 72/08 (20130101) H04W 72/0453 (20130101) H04W 88/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104601 | Smith |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SR Technologies, Inc. (Davie, Florida) |
| ASSIGNEE(S) | SR Technologies, Inc. (Davie, Florida) |
| INVENTOR(S) | Graham K. Smith (Boca Raton, Florida) |
| ABSTRACT | A method and a node identification system for identifying at least one unknown mobile node in a communications network using details related to at least one known mobile node and organization of the details related to the at least one known mobile node. The method includes capturing details related to the at least one unknown mobile node and identifying an organization of the captured details related to the at least one unknown mobile node, comparing the details related to the at least one known mobile node and the organization of the details related to the at least one known mobile node with the captured details related to the at least one unknown mobile node and the organization of the captured details related to the at least one unknown mobile node, and determining a type of the at least one unknown mobile node based on the comparing. |
| FILED | Wednesday, September 06, 2017 |
| APPL NO | 15/696251 |
| ART UNIT | 2416 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0853 (20130101) H04L 61/2038 (20130101) H04L 61/2092 (20130101) H04L 61/6022 (20130101) Wireless Communication Networks H04W 48/14 (20130101) H04W 48/16 (20130101) Original (OR) Class H04W 84/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104805 | Lazarus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nathan S. Lazarus (Bethesda, Maryland); Christopher P. Migliaccio (Albuquerque, New Mexico) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Nathan S. Lazarus (Bethesda, Maryland); Christopher P. Migliaccio (Albuquerque, New Mexico) |
| ABSTRACT | Self-cooling stretchable electrical circuits with a conduit forming an electrical component and containing electrically conductive liquid are disclosed. They are formed of a platform made of a stretchable material. At least one fluid conduit is formed in the platform and the conduit is formed into an electrical component and filled with the electrically conductive liquid metal. A portion of the conduit is positioned adjacent a heat sink while a pump circulates the liquid through the conduit wherein the metal is cooled at the heat sink. |
| FILED | Monday, May 09, 2016 |
| APPL NO | 15/149731 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0283 (20130101) H05K 7/20263 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D831121 | Fea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Michael J. Fea (Lorton, Virginia); Amy J. Dalmas (Manassas, Virginia); Sharon Carrillo (San Antonio, Texas) |
| ABSTRACT | |
| FILED | Friday, December 01, 2017 |
| APPL NO | 29/628072 |
| ART UNIT | 2913 — Design |
| CURRENT CPC | Games, toys, and sports goods D21/365 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10099178 | Stewart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Frederick F. Stewart (Idaho Falls, Idaho); Michael T. Benson (Idaho Falls, Idaho); Mark L. Stone (Idaho Falls, Idaho) |
| ABSTRACT | A method of treating an aqueous liquid. The method comprises providing an aqueous feed liquid comprising water and at least one solute to a first side of a membrane. A draw solution comprising water and a draw solute comprising at least one of a phosphazene compound and a triazine compound is provided to a second side of the membrane. At least a portion of the water of the aqueous feed liquid is osmosed across the membrane and into the draw solution to form a diluted draw solution comprising water and the draw solute. The water of the diluted draw solution is separated from the draw solute of the diluted draw solution to form a purified water product. Draw solutes comprising phosphazene compounds and draw solutes comprising triazine compounds are also disclosed, as are methods of forming the draw solutes. |
| FILED | Friday, November 20, 2015 |
| APPL NO | 14/948019 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/005 (20130101) Original (OR) Class B01D 61/007 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/445 (20130101) C02F 2103/08 (20130101) Heterocyclic Compounds C07D 251/54 (20130101) C07D 251/70 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65815 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099207 | Stamenkovic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Vojislav Stamenkovic (Naperville, Illinois); Nenad Markovic (Hinsdale, Illinois); Yijin Kang (Naperville, Illinois) |
| ABSTRACT | A multimetallic core/interlayer/shell nanoparticle comprises an inner core formed from a first metal. An interlayer is disposed on the first layer. The interlayer includes a plurality of gold atoms. An outer shell is disposed over the interlayer. The outer shell includes platinum and the first metal. A surface of the NP is substantially free of gold. The first metal is selected from the group consisting of nickel, titanium, chromium, manganese, iron, cobalt, copper, vanadium, yttrium, ruthenium, palladium, scandium, tin, lead and zinc. |
| FILED | Thursday, April 02, 2015 |
| APPL NO | 14/677707 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/892 (20130101) Original (OR) Class B01J 35/008 (20130101) B01J 35/0013 (20130101) B01J 35/0033 (20130101) B01J 37/08 (20130101) B01J 37/16 (20130101) B01J 37/0211 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/92 (20130101) H01M 4/8657 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/892 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099290 | Lacy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Benjamin Paul Lacy (Greer, South Carolina); Srikanth Chandrudu Kottilingam (Simpsonville, South Carolina); David Edward Schick (Greenville, South Carolina) |
| ABSTRACT | A hybrid additive manufacturing method comprises building an additive structure on a pre-sintered preform base, wherein building the additive structure comprises iteratively fusing together a plurality of layers of additive material with at least a first layer of additive material joined to the pre-sintered preform base, and wherein the pre-sintered preform base comprises an initial shape. The hybrid additive manufacturing method further comprises modifying the initial shape of the pre-sintered preform base comprising the additive structure into a modified shape comprising the additive structure, and, joining the pre-sintered preform base in its modified shape to a component. |
| FILED | Thursday, December 18, 2014 |
| APPL NO | 14/574557 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/24 (20130101) B22F 3/1055 (20130101) B22F 5/04 (20130101) B22F 5/009 (20130101) B22F 7/06 (20130101) B22F 7/08 (20130101) Original (OR) Class B22F 7/062 (20130101) B22F 2005/005 (20130101) B22F 2301/15 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 10/027 (20130101) B23K 26/0006 (20130101) B23K 26/342 (20151001) B23K 2203/05 (20151001) B23K 2203/08 (20130101) B23K 2203/10 (20130101) B23K 2203/14 (20130101) B23K 2203/18 (20130101) B23K 2203/26 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Alloys C22C 19/07 (20130101) C22C 19/057 (20130101) C22C 19/058 (20130101) Cyclically Operating Valves for Machines or Engines F01L 9/02 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/295 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099458 | Haq et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Mahmoodul Haq (Okemos, Michigan); Lawrence T. Drzal (Okemos, Michigan); Ermias G. Koricho (Okemos, Michigan) |
| ABSTRACT | The disclosure relates to reversible bonded structural joints using active adhesive compositions that can allow for dis-assembly, repair, and re-assembly. The disclosure is particularly directed to the adhesive composition material, irrespective of the type of the substrate(s) being joined. The adhesive composition can include any thermoplastic adhesive material that can be remotely activated for targeted heating of just the adhesive composition (e.g., and not the surrounding substrates being joined) via the inclusion of electromagnetically excitable particles in the adhesive composition. The substrates can be any metal material, any composite material, any hybrid material, or otherwise. The disclosed adhesive compositions allow for recyclability of parts at the end of their lifetime and repair/replacement of parts during their lifetime. |
| FILED | Wednesday, March 23, 2016 |
| APPL NO | 15/078333 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/76 (20130101) B29C 65/148 (20130101) B29C 65/368 (20130101) B29C 65/489 (20130101) B29C 65/1425 (20130101) B29C 65/3612 (20130101) B29C 65/3696 (20130101) B29C 65/4815 (20130101) B29C 65/4855 (20130101) B29C 65/4875 (20130101) B29C 65/4885 (20130101) B29C 65/5071 (20130101) B29C 65/5085 (20130101) B29C 65/8207 (20130101) B29C 66/14 (20130101) B29C 66/43 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/71 (20130101) B29C 66/112 (20130101) B29C 66/131 (20130101) B29C 66/322 (20130101) B29C 66/721 (20130101) B29C 66/742 (20130101) B29C 66/919 (20130101) B29C 66/1122 (20130101) B29C 66/1142 (20130101) B29C 66/1162 (20130101) B29C 66/1222 (20130101) B29C 66/1224 (20130101) B29C 66/7212 (20130101) B29C 66/7212 (20130101) B29C 66/7212 (20130101) B29C 66/7392 (20130101) B29C 66/7394 (20130101) B29C 66/7422 (20130101) B29C 66/8322 (20130101) B29C 66/12441 (20130101) B29C 66/30326 (20130101) B29C 66/43441 (20130101) B29C 66/74283 (20130101) B29C 66/83221 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) B29K 2077/00 (20130101) B29K 2105/162 (20130101) B29K 2307/04 (20130101) B29K 2309/08 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/30 (20130101) B29L 2031/3076 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/08 (20130101) B32B 27/34 (20130101) Original (OR) Class B32B 27/38 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/04 (20130101) C08K 3/08 (20130101) C08K 3/22 (20130101) C08K 3/041 (20170501) C08K 3/042 (20170501) C08K 3/042 (20170501) C08K 3/046 (20170501) C08K 7/06 (20130101) C08K 7/18 (20130101) C08K 9/02 (20130101) C08K 2003/2227 (20130101) C08K 2201/01 (20130101) Compositions of Macromolecular Compounds C08L 23/00 (20130101) C08L 23/0853 (20130101) C08L 33/08 (20130101) C08L 53/00 (20130101) C08L 55/02 (20130101) C08L 67/00 (20130101) C08L 69/00 (20130101) C08L 75/04 (20130101) C08L 77/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 177/02 (20130101) C09J 177/02 (20130101) C09J 177/02 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 11/006 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099925 | Poshusta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ultra-Charge, Ltd. (Haifa OT, Israel) |
| ASSIGNEE(S) | Ultra-Charge, Ltd. (Haifa, Israel) |
| INVENTOR(S) | Joseph Carl Poshusta (Broomfield, Colorado); Ryon Tracy (Westminster, Colorado) |
| ABSTRACT | The present invention provides a process for producing hydrogen bis(fluorosulfonyl)-imide (HFSI) by fluorination of a liquid hydrogen bis(chlorosulfonyl)imide (HCSI) using a gaseous hydrogen fluoride. In some embodiments, HFSI that is produced is separated from the reaction mixture as a gas and is condensed to collect a liquid HFSI. |
| FILED | Saturday, December 03, 2016 |
| APPL NO | 15/368592 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/093 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099945 | Choi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Siwon Choi (Cambridge, Massachusetts); Jongyoon Han (Bedford, Massachusetts) |
| ABSTRACT | Between two juxtaposed similar ion exchange membranes (AEMs or CEMs), an ion depletion zone and ion enrichment zone are generated under an electric field. As cations are selectively transferred through the CEMs, for example, anions are relocated in order to achieve electro-neutrality, resulting in the concentration drop (increase) in ion depletion (enrichment) zone. The use of a sacrificial metal anode allows electrocoagulation (EC) concurrently with ICP thereby permitting concentration of both ionic and non-ionic impurities to occur at the same time within the same cell or device. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 15/815803 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 61/42 (20130101) B01D 2311/2642 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/463 (20130101) Original (OR) Class C02F 1/469 (20130101) C02F 1/4604 (20130101) C02F 2103/08 (20130101) C02F 2201/46115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099994 | Dzwiniel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trevor L. Dzwiniel (Carol Stream, Illinois); Krzysztof Pupek (Plainfield, Illinois); Gregory K. Krumdick (Homer Glen, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Trevor L. Dzwiniel (Carol Stream, Illinois); Krzysztof Pupek (Plainfield, Illinois); Gregory K. Krumdick (Homer Glen, Illinois) |
| ABSTRACT | A method for producing halogenated carbonates is provided, the method having the steps of reacting a halogenated hydroxyl moiety with an alkyl formate in the presence of a liquid solvent and a solid base. An exemplary halogenated carbonate so produced is trifluoroethyl methyl carbonate. |
| FILED | Monday, September 12, 2016 |
| APPL NO | 15/262603 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 68/06 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100150 | Grate et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jay W. Grate (Richland, Washington); Kai-For Mo (Richland, Washington); Michael D. Daily (Austin, Texas) |
| ABSTRACT | Disclosed herein are monomer embodiments that can be used to make polymers, such as homopolymers, heteropolymers, and that can be used in particular embodiments to make sequence-defined polymers. Also disclosed herein are methods of making polymers using such monomer embodiments. Methods of using the polymers disclosed herein also are described. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 15/374955 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/065 (20130101) C08G 73/0273 (20130101) C08G 73/0644 (20130101) Original (OR) Class C08G 73/0655 (20130101) Compositions of Macromolecular Compounds C08L 79/02 (20130101) C08L 79/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100325 | Clemente et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Thomas E. Clemente (Lincoln, Nebraska); Hyunwoo Park (Kyeonggi, South Korea); Edgar Cahoon (Lincoln, Minnesota); Hanh Nguyen (Lincoln, Nebraska) |
| ABSTRACT | Methods of genetically modifying soybean plants to alter the fatty acid properties of the oil are described. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 14/815377 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100342 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cargill, Incorporated (Wayzata, Minnesota); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | CARGILL, INCORPORATED (Wayzata, Minnesota) |
| INVENTOR(S) | Michael D Lynch (Boulder, Colorado); Ryan T. Gill (Denver, Colorado); Tanya E. W. Lipscomb (Boulder, Colorado) |
| ABSTRACT | This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product, which includes 3-hydroxypropionic acid. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/167439 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/12 (20130101) C12N 9/16 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 11/00 (20130101) Original (OR) Class Enzymes C12Y 102/04001 (20130101) C12Y 207/00 (20130101) C12Y 301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100369 | Ozanich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Richard M. Ozanich (Richland, Washington); Janine R. Hutchison (Richland, Washington); Kristin D. Victry (Richland, Washington); Becky M. Hess (Richland, Washington) |
| ABSTRACT | A method for amplifying and detecting microorganisms, such as species of Listeria, is described. The method utilizes gene-matched enrichment media and PCR-based detection. The enrichment media is spent media produced using a modified microorganism containing a plurality of mutations in a selected gene such that the modified microorganism does not contain the PCR signature. Thus, PCR detects only the amplified microorganism of interest, not the modified microorganism. Exemplary methods and kits for amplification and detection of Listeria species are described. |
| FILED | Wednesday, June 17, 2015 |
| APPL NO | 14/742367 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100512 | Modera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Mark Modera (Piedmont, California); Curtis Harrington (West Sacramento, California); Nelson Dichter (Scotts Valley, California) |
| ABSTRACT | A system and method for detecting, marking and/or sealing building envelope leaks in buildings or any enclosed structure. Fogs of aerosolized sealant particles that have a surface tackiness that diminishes over time are introduced into the interior of prepared rooms. The surface properties of the aerosol particles can be controlled with the selection of sealant composition, including the presence and concentration of solvents, the range of produced particle sizes, and the relative humidity and temperature within the enclosure. A pressure differential is created and the micron scale particles adhere to the leak edges and to other particles as they are brought to the leaks and then leave the gas streamlines. Control of particle size, drying rate and particle residence time in the building interior allows control over the treatment area so that leaks are sealed without leaving a tacky residue. |
| FILED | Monday, September 26, 2016 |
| APPL NO | 15/276495 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/14 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/66 (20130101) Original (OR) Class Pistons; Cylinders; Sealings F16J 15/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100666 | Brzek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Brian Gene Brzek (Clifton Park, New York); Victor John Morgan (Greenville, South Carolina); Benjamin Paul Lacy (Greer, South Carolina) |
| ABSTRACT | A hot gas path component for a turbine system is disclosed. The hot gas path component includes a shell and one or more porous media having an exterior surface and an interior surface and positioned adjacent the shell. The one or more porous media is configured to include varying permeability in one of an axial direction, a radial direction, an axial and a radial direction, an axial and a circumferential direction, a radial and a circumferential direction or an axial, a radial and a circumferential direction, the porous media is positioned adjacent the shell. The one or more porous media is further configured to control one of an axial, a radial, an axial and a radial, an axial and a circumferential, a radial and a circumferential or an axial, a radial and a circumferential flow of a cooling medium flowing therethrough. |
| FILED | Friday, March 29, 2013 |
| APPL NO | 13/853556 |
| ART UNIT | 3748 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/183 (20130101) F01D 5/186 (20130101) F01D 9/02 (20130101) F01D 9/041 (20130101) F01D 25/12 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/514 (20130101) F05D 2300/612 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Y02T 50/673 (20130101) Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100719 | Moore |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | DELPHI TECHNOLOGIES IP LIMITED (, Barbados) |
| INVENTOR(S) | Wayne R. Moore (Goodrich, Michigan) |
| ABSTRACT | A GDCI engine control system provides rapid heating of intake air to the combustion chamber when the engine is cold. The engine uses an intake air pathway that includes a compressor having a compressor inlet and a compressor outlet. A loop fluidly connects the compressor outlet to the compressor inlet. First and second valves are arranged in the loop and are arranged near the compressor outlet and the compressor inlet respectively. First and second passages converge at a first junction, and the first passage fluidly connects the first valve and the first junction. The second passage fluidly connects to the loop at a second junction arranged fluidly between the first and second valves. An intake air heat exchanger is arranged in the first passage and fluidly between the first valve and the first junction. |
| FILED | Monday, July 18, 2016 |
| APPL NO | 15/212882 |
| ART UNIT | 3748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 29/0418 (20130101) F02B 33/44 (20130101) Original (OR) Class Controlling Combustion Engines F02D 41/0007 (20130101) F02D 41/144 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 35/108 (20130101) F02M 35/1038 (20130101) F02M 35/10157 (20130101) F02M 35/10255 (20130101) F02M 35/10268 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100737 | Little et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David A. Little (Chuluota, Florida); Clifford E. Johnson (Orlando, Florida) |
| ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
| INVENTOR(S) | David A. Little (Chuluota, Florida); Clifford E. Johnson (Orlando, Florida) |
| ABSTRACT | A cooling arrangement (100), including: a substrate having a pocket (24) defined by a rib side surface (28) and a bottom surface (26); a feature (112) formed in the rib side surface; and an impingement plate (102). In an installed configuration (116) a resilience of the impingement plate enables an interference between the impingement plate and the feature that locks the impingement plate in an installed position (118). An elastic compression of the impingement plate from the installed configuration eliminates the interference. |
| FILED | Thursday, May 16, 2013 |
| APPL NO | 13/895831 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/023 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/201 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 2900/03042 (20130101) F23R 2900/03044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100850 | Raymond |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | David W. Raymond (Edgewood, New Mexico) |
| ABSTRACT | A modular motor is disclosed that includes a piston/harmonic drive assembly that is axially cycled. The piston/harmonic drive assembly is coupled to a ball transfer arrangement that converts the axial motion into rotary motion to rotate a rotor that can be used to rotate a drill bit. |
| FILED | Monday, April 04, 2016 |
| APPL NO | 15/090282 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/183 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 4/14 (20130101) Machines or Engines, in General or of Positive-displacement Type, e.g Steam Engines F01B 1/00 (20130101) F01B 11/04 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101429 | Deng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Zhiqun Deng (Richland, Washington); Huidong Li (Richland, Washington); Jun Lu (Richland, Washington); Mitchell J. Myjak (Richland, Washington); Jayson J. Martinez (Richland, Washington); Jie Xiao (Richland, Washington); Richard S. Brown (Richland, Washington); Samuel S. Cartmell (Richland, Washington) |
| ABSTRACT | A new acoustic tag and process are disclosed for identifying and tracking underwater hosts in up to three dimensions. The acoustic tag has an operation lifetime up to a year or longer at a pulse rate interval of about 15 seconds. The acoustic tag has a signal detection range up to at least about 500 meters that enhances detection probability. |
| FILED | Wednesday, February 25, 2015 |
| APPL NO | 14/631587 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/006 (20130101) A01K 61/90 (20170101) Diagnosis; Surgery; Identification A61B 5/07 (20130101) A61B 5/0015 (20130101) A61B 5/1112 (20130101) A61B 2503/40 (20130101) A61B 2562/08 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/72 (20130101) Original (OR) Class G01S 5/18 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 17/00 (20130101) G06K 19/0728 (20130101) Transmission H04B 1/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102179 | Shalf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | John Shalf (Oakland, California); David Donofrio (San Francisco, California); Leonid Oliker (San Francisco, California) |
| ABSTRACT | A multi-core computer processor including a plurality of processor cores interconnected in a Network-on-Chip (NoC) architecture, a plurality of caches, each of the plurality of caches being associated with one and only one of the plurality of processor cores, and a plurality of memories, each of the plurality of memories being associated with a different set of at least one of the plurality of processor cores and each of the plurality of memories being configured to be visible in a global memory address space such that the plurality of memories are visible to two or more of the plurality of processor cores. |
| FILED | Monday, August 22, 2016 |
| APPL NO | 15/243634 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0811 (20130101) G06F 12/0813 (20130101) G06F 12/0815 (20130101) G06F 12/0833 (20130101) G06F 12/0842 (20130101) G06F 12/1081 (20130101) G06F 15/7825 (20130101) Original (OR) Class G06F 2212/62 (20130101) G06F 2212/283 (20130101) G06F 2212/608 (20130101) G06F 2212/621 (20130101) G06F 2212/656 (20130101) G06F 2212/1008 (20130101) G06F 2212/1021 (20130101) G06F 2212/1041 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/13 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102382 | Hart |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Mark Miles Hart (Livermore, California) |
| ABSTRACT | An Initialization Unit (IU) initiates an initial secure connection with an Intrinsic Use Control (IUC) Chip based on very large random numbers (VLRNs). The IUC Chip in turn initiates a secondary secure connection between it and one or more Use Controlled Components (UCCs). Polling by the IU allows confirmation of an ongoing secure connection, and also allows the IUC Chip to confirm the secondary secure connection to the UCCs. Removal or improper polling response from one of the UCCs results in a response from the IUC Chip that may include notification of tampering, or temporary or permanent discontinued operation of the offending UCC. Permanent discontinued operation may include destruction of the offending UCC, and cascaded discontinued operation of all other UCCs secured by the IUC Chip. A UCC may in turn be another nested layer of IUC Chips, controlling a corresponding layer of UCCs, ad infinitum. |
| FILED | Monday, August 31, 2015 |
| APPL NO | 14/841116 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/60 (20130101) Original (OR) Class G06F 21/71 (20130101) G06F 2221/2141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102979 | Voelker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Miltec Corporation (Stevensville, Maryland) |
| ASSIGNEE(S) | Miltec Corporation (Stevensville, Maryland) |
| INVENTOR(S) | Gary Voelker (Bumpass, Virginia); John Arnold (Pittstown, New Jersey); Joseph Fasolo (Edgewood, Maryland) |
| ABSTRACT | A process for manufacturing an electrode utilizing electron beam (EB) or actinic radiation to cure the electrode binder is provided. A process is also disclosed for mixing specific actinic or EB radiation curable polymer precursors with electrode solid particles to form an aqueous mixture, application of the mixture to an electrode current collector, followed by the application of actinic or EB radiation to the current collector for curing the polymer, thereby binding the electrode binder to the current collector. Lithium ion batteries, electric double layer capacitors, and components produced therefrom are also provided. |
| FILED | Friday, May 16, 2014 |
| APPL NO | 14/279963 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/28 (20130101) H01G 11/48 (20130101) Original (OR) Class H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/139 (20130101) H01M 4/0404 (20130101) H01M 4/622 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102982 | Nanda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jagjit Nanda (Knoxville, Tennessee); Rose E. Ruther (Oak Ridge, Tennessee); Frank M. Delnick (Maryville, Tennessee); Che-Nan Sun (Williamsville, New York) |
| ABSTRACT | A supercapacitor and a related electrolyte composition suitable for use in a supercapacitor are provided. An electrolyte composition can include a conductive sodium salt component comprising NaTFSI and a non-aqueous solvent component comprising dimethoxy ethane (DME). The conductive sodium salt component and the non-aqueous solvent component can be present at a molar ratio of NaTFSI:DME of 1:1 to 1:3, inclusive. |
| FILED | Wednesday, March 02, 2016 |
| APPL NO | 15/058434 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/04 (20130101) H01G 11/60 (20130101) Original (OR) Class H01G 11/62 (20130101) H01G 11/64 (20130101) H01G 11/84 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103391 | Parsons |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jason B. Parsons (Manchester, Connecticut) |
| ASSIGNEE(S) | AUDI AG (Ingolstadt, Germany) |
| INVENTOR(S) | Jason B. Parsons (Manchester, Connecticut) |
| ABSTRACT | An example fuel cell seal assembly includes a seal configured to restrict flow of a fuel cell fluid through at least one of an outer lateral edge of a first gas diffusion layer, an outer lateral edge of a membrane electrode assembly, and an outer lateral edge of a second gas diffusion layer. The outer lateral edge of the first gas diffusion layer is laterally spaced from the outer lateral edge of the second gas diffusion layer. An example method of sealing a fuel cell interface includes limiting flow of a fuel cell fluid using a seal configured to restrict flow through an outwardly facing edge of at least one of a first gas diffusion layer and an outwardly facing edge of a second gas diffusion layer. The outwardly facing edge of the first gas diffusion layer is spaced from the outwardly facing edge of the second gas diffusion layer. |
| FILED | Friday, January 28, 2011 |
| APPL NO | 13/981381 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0271 (20130101) Original (OR) Class H01M 8/0273 (20130101) H01M 8/0276 (20130101) H01M 8/0297 (20130101) H01M 8/1004 (20130101) H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103408 | Wiesner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Ulrich Wiesner (Ithaca, New York); Joerg G. Werner (Greece, New York); Héctor D. Abruña (Ithaca, New York); Gabriel Rodriguez-Calero (Ithaca, New York) |
| ABSTRACT | A solid-state three-dimensional battery assembly includes a solid bicontinuous monolithic carbon anode, a solid electrolyte layer, and a solid cathode. The solid monolithic carbon anode has an ordered three-dimensionally continuous network nanostructure, a length of at least 100 nm, and an average thickness of 3 to 90 nm. The ordered three-dimensionally continuous network nanostructure of the anode defines a plurality of pores having an average diameter of 5 to 100 nm. The solid electrolyte layer is disposed directly on the anode, has an average thickness of 3 to 90 nm, and fills a portion of the pores defined by the ordered three-dimensionally continuous network nanostructure of the anode. The solid cathode is disposed directly on the electrolyte layer, has an average thickness of 3 to 90 nm, and also fills a portion of the pores defined by the ordered three-dimensionally continuous network nanostructure of the anode. Related devices and methods are also provided. |
| FILED | Friday, August 26, 2016 |
| APPL NO | 15/753820 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/66 (20130101) H01M 4/0407 (20130101) H01M 4/0471 (20130101) H01M 4/587 (20130101) H01M 4/1393 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 10/0585 (20130101) Original (OR) Class H01M 2004/021 (20130101) H01M 2004/027 (20130101) H01M 2220/30 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103666 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lingling Fan (Tampa, Florida); Zhixin Miao (Tampa, Florida); Hossein Ghassempour Aghamolki (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Lingling Fan (Tampa, Florida); Zhixin Miao (Tampa, Florida); Hossein Ghassempour Aghamolki (Tampa, Florida) |
| ABSTRACT | Various examples are related to synchronous generator modeling with frequency control, which can be achieved using unscented Kalman filtering. In one example, a method includes obtaining operational parameters associated with a generator of a power system; determining parameters of a synchronous generator model with frequency control based at least in part upon the operational parameters associated with the generator; and providing a command to a frequency control of the generator, the command updating one or more parameters of the frequency control. In another example, a system includes a generator controller for a generator of a power system; and a computing device in communication with the generator controller, where the computing device is configured to determine parameters of the synchronous generator model using operational parameters associated with the generator and provide a command updating one or more parameters of a frequency control of the generator controller. |
| FILED | Wednesday, November 30, 2016 |
| APPL NO | 15/364950 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103733 | Gurrieri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Thomas M. Gurrieri (Albuquerque, New Mexico); Jason R. Hamlet (Albuquerque, New Mexico); Todd M. Bauer (Albuquerque, New Mexico); Ryan Helinski (Albuquerque, New Mexico); Lyndon G. Pierson (Albuquerque, New Mexico) |
| ABSTRACT | An integrated circuit (IC) based physically unclonable function (PUF) that comprises a common source amplifier for generating PUF output voltages, a unity gain, negative feedback operational amplifier for generating bias voltages, a voltage regulator and a bit exclusion circuit that excludes unstable PUF bits. Compensation circuitry built into the IC-PUF provides a high power supply rejection ratio and enables highly reliable operation of the IC-PUF across varying input voltages and operating temperatures. The IC-PUF generates a uniformly random output bit stream by taking advantage of process variations that are inherent to the fabrication of (metal-oxide semiconductor) MOS transistors. |
| FILED | Monday, November 20, 2017 |
| APPL NO | 15/817870 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 19/00315 (20130101) Original (OR) Class H03K 19/17768 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104202 | Aho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael E. Aho (Rochester, Minnesota); John E. Attinella (Rochester, Minnesota); Thomas M. Gooding (Rochester, Minnesota); Samuel J. Miller (Rochester, Minnesota) |
| ABSTRACT | Techniques are disclosed for loading programs efficiently in a parallel computing system. In one embodiment, nodes of the parallel computing system receive a load description file which indicates, for each program of a multiple program multiple data (MPMD) job, nodes which are to load the program. The nodes determine, using collective operations, a total number of programs to load and a number of programs to load in parallel. The nodes further generate a class route for each program to be loaded in parallel, where the class route generated for a particular program includes only those nodes on which the program needs to be loaded. For each class route, a node is selected using a collective operation to be a load leader which accesses a file system to load the program associated with a class route and broadcasts the program via the class route to other nodes which require the program. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/801165 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/445 (20130101) G06F 9/4806 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10098967 | Parquette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Jonathan R. Parquette (Columbus, Ohio); Se Hye Kim (Columbus, Ohio); Mark W. Grinstaff (Brookline, Massachusetts); Jonah A. Kaplan (Newton, Massachusetts) |
| ABSTRACT | Disclosed are conjugates of hydrophobic drugs linked to protected or unprotected amino acids or peptides. The disclosed conjugates are amphiphilic and can self assemble into nantubes. Nanotubes comprising the conjugates are also described and can have high loading of the drug and protect it from degradation or elimination. The nanotubes are well suited to deliver hydrophobic and unstable drugs to individuals. |
| FILED | Tuesday, December 03, 2013 |
| APPL NO | 14/095816 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/62 (20170801) Original (OR) Class A61K 47/542 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099437 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gurpreet Singh (Akron, Ohio); Alamgir Karim (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Gurpreet Singh (Akron, Ohio); Alamgir Karim (Akron, Ohio) |
| ABSTRACT | Directionally oriented block copolymer films and zone annealing processes for producing directionally oriented block films are provided. The zone annealing processes include methods of inducing horizontally oriented block copolymers through a soft sheer process and methods of inducing vertically oriented block copolymers via sharp dynamic zone annealing. The zone annealing processes are capable of both small and large scale production of directionally oriented block films. The cold zone annealing processes are also capable of being combined with graphoepitaxy methods. |
| FILED | Wednesday, June 05, 2013 |
| APPL NO | 14/405844 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/24 (20130101) B29C 71/02 (20130101) Original (OR) Class B29C 71/0072 (20130101) B29C 2071/022 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2096/04 (20130101) B29K 2105/0085 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/008 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00031 (20130101) B81C 2201/0149 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2353/00 (20130101) C08J 2383/10 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099920 | Shen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jie Shen (Worcester, Massachusetts); Wei Sun (Brookline, Massachusetts); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | The present disclosure relates to the alignment of moieties (e.g., nanoparticles and/or nanowires) into prescribed architectures on two- and/or three-dimensional substrates (e.g., nucleic acid nanostructures/crystals). The present disclosure also relates to a nucleic acid (e.g., DNA) lithography method that includes, in some embodiments, adsorbing a bare nucleic acid nanostructure onto a surface of a substrate, and etching the surface of the substrate containing the bare nucleic acid nanostructure, thereby producing a patterned substrate. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 15/312854 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00659 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0047 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099928 | Tse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Stephen D. Tse (Warren, New Jersey); Nasir K. Memon (Piscataway, New Jersey); Bernard H. Kear (Whitehouse Station, New Jersey) |
| ABSTRACT | Apparatus and methods of use thereof for the production of carbon-based and other nanostructures, as well as fuels and reformed products, are provided. |
| FILED | Thursday, May 12, 2016 |
| APPL NO | 15/152920 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/323 (20130101) C01B 3/363 (20130101) C01B 31/0293 (20130101) Original (OR) Class C01B 2203/0255 (20130101) C01B 2203/1223 (20130101) C01B 2203/1241 (20130101) C01B 2203/1247 (20130101) Burners F23D 14/22 (20130101) F23D 14/32 (20130101) F23D 14/56 (20130101) F23D 14/58 (20130101) F23D 14/78 (20130101) F23D 14/84 (20130101) F23D 91/02 (20150701) F23D 2900/00001 (20130101) F23D 2900/21007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099950 | Silver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthew Silver (Cambridge, Massachusetts); Justin Buck (Cambridge, Massachusetts); Patrick Kiely (Brighton, Massachusetts); Juan J. Guzman (Medford, Massachusetts) |
| ASSIGNEE(S) | CAMBRIAN INNOVATION LLC (Watertown, Massachusetts) |
| INVENTOR(S) | Matthew Silver (Cambridge, Massachusetts); Justin Buck (Cambridge, Massachusetts); Patrick Kiely (Brighton, Massachusetts); Juan J. Guzman (Medford, Massachusetts) |
| ABSTRACT | The invention relates to bio-electrochemical systems for treating wastewater, and sour gas produced by anaerobic digestion of organic material. The invention further relates to novel anode/cathode pairing schemes, and electric and hydraulic architectures for use in bio-electrochemical systems. |
| FILED | Thursday, April 14, 2011 |
| APPL NO | 13/811132 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/283 (20130101) C02F 1/46109 (20130101) C02F 1/46114 (20130101) C02F 3/005 (20130101) Original (OR) Class C02F 3/345 (20130101) C02F 3/1273 (20130101) C02F 3/2826 (20130101) C02F 2001/46133 (20130101) C02F 2001/46157 (20130101) C02F 2101/006 (20130101) C02F 2103/002 (20130101) C02F 2103/005 (20130101) C02F 2201/4611 (20130101) C02F 2201/46115 (20130101) C02F 2201/46135 (20130101) C02F 2301/08 (20130101) C02F 2303/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/343 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/15 (20150501) Y02W 10/30 (20150501) Y02W 10/37 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10099981 | Ferreira et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Eric Ferreira (Athens, Georgia); Qiankun Li (Taihe, China PRC) |
| ABSTRACT | Provided are methods for the meta-selective C—H arylations of arene alcohol-based substrates. The methods combine the transient norbornene strategy with a quinoline-based acetal scaffold to achieve the formation of biaryl compounds. These processes establish a foundation for catalytic polyfunctionalization of alcohol-based compounds. The method comprises attaching a heterocyclic hemiacetal scaffold to an aromatic alcohol or a substituted aromatic alcohol; reacting the aromatic or substituted aromatic alcohol having the heterocyclic hemiacetal scaffold attached with an alkyl or aryl iodide in a reaction mix comprising a palladium catalyst, a silver salt, and carboxymethyl norbornene to generate a meta-arylated arene conjugated to the heterocyclic hemiacetal scaffold; and then cleaving the heterocyclic hemiacetal scaffold from the meta-arylated arene alcohol. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809305 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 41/18 (20130101) Original (OR) Class C07C 41/28 (20130101) C07C 41/28 (20130101) C07C 43/23 (20130101) C07C 45/64 (20130101) C07C 45/64 (20130101) C07C 45/673 (20130101) C07C 49/84 (20130101) C07C 67/31 (20130101) C07C 67/31 (20130101) C07C 67/31 (20130101) C07C 67/31 (20130101) C07C 67/333 (20130101) C07C 69/76 (20130101) C07C 69/94 (20130101) C07C 69/734 (20130101) C07C 201/12 (20130101) C07C 201/12 (20130101) C07C 205/37 (20130101) C07C 269/06 (20130101) C07C 269/06 (20130101) C07C 271/28 (20130101) C07C 2603/86 (20170501) Heterocyclic Compounds C07D 209/08 (20130101) C07D 317/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100014 | Newkome et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George R. Newkome (Medina, Ohio); Charles N. Moorefield (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | George R. Newkome (Medina, Ohio); Charles N. Moorefield (Akron, Ohio) |
| ABSTRACT | Metallotriangle-based nanomolecules are formed by a one-step self-assembly of specifically chosen shaped poly-ligand monomers, the poly-ligand monomers coordinating with metal ions through coordinating ligands. The poly-ligand monomers are defined by vertex groups having arms extending therefrom and ending in coordinating ligands. Based on the desired metallotriangle-based nanomolecule structure to be assembled, specifically shaped poly-ligand monomers and metal ions are chosen and mixed in appropriate ratios so that coordinating ligands bind to metal ions and the poly-ligand monomers thus spontaneously self-assemble into the desired metallotriangle-based nanomolecule structure. |
| FILED | Wednesday, January 27, 2016 |
| APPL NO | 15/007456 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Heterocyclic Compounds C07D 213/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100074 | Gervay-Hague et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jacquelyn Gervay-Hague (Davis, California); Matthew Schombs (Oxford, United Kingdom) |
| ABSTRACT | The present invention provides novel, regioselectively-acylated oligosaccharide compounds and methods for preparing them. In another aspect, the. invention provides a method for preparing a selectively-acylated oligosaccharide. The method includes forming a reaction mixture containing a protected oligosaccharide and an acylating agent. The protected oligosaccharide includes at least three hydroxyl moieties and each hydroxyl moiety is protected with a silyl protecting group. The reaction mixture is formed under conditions sufficient to selectively replace at least one silyl protecting group with a —C(0)-C1_6 alkyl group, and the selectively-acylated oligosaccharide comprises at least one —C(0)-C1_6 alkyl group and at least one silyl protecting group. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 14/975537 |
| ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/06 (20130101) C07H 13/04 (20130101) Original (OR) Class C07H 23/00 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100266 | Malshe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Ajay P. Malshe (Springdale, Arkansas); Wengyang Zhang (Springdale, Arkansas) |
| ABSTRACT | A dielectric nanolubricant composition is provided. The dielectric nanolubricant composition includes a nano-engineered lubricant additive dispersed in a base. The nano-engineered lubricant additive may include a plurality of solid lubricant nanostructures having an open-ended architecture and an organic, inorganic, and/or polymeric medium intercalated in the nanostructures and/or encapsulate nanostructures. The base may include a grease or oil such as silicone grease or oil, lithium complex grease, lithium grease, calcium sulfonate grease, silica thickened perfluoropolyether (PFPE) grease or PFPE oil, for example. This dielectric nanolubricant composition provides better corrosion and water resistance, high dielectric strength, longer material life, more inert chemistries, better surface protection and asperity penetration, no curing, no staining, and environmentally friendly, compared to current products in the market. |
| FILED | Friday, August 11, 2017 |
| APPL NO | 15/675231 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/61 (20180101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 125/22 (20130101) C10M 169/04 (20130101) Original (OR) Class C10M 169/042 (20130101) C10M 171/06 (20130101) C10M 177/00 (20130101) C10M 2201/04 (20130101) C10M 2201/06 (20130101) C10M 2201/041 (20130101) C10M 2201/042 (20130101) C10M 2201/061 (20130101) C10M 2201/062 (20130101) C10M 2201/065 (20130101) C10M 2201/066 (20130101) C10M 2201/081 (20130101) C10M 2201/082 (20130101) C10M 2201/084 (20130101) C10M 2201/087 (20130101) C10M 2201/103 (20130101) C10M 2201/0663 (20130101) C10M 2203/0206 (20130101) C10M 2203/1006 (20130101) C10M 2203/1025 (20130101) C10M 2205/163 (20130101) C10M 2207/401 (20130101) C10M 2207/0406 (20130101) C10M 2207/1285 (20130101) C10M 2207/2815 (20130101) C10M 2207/2835 (20130101) C10M 2207/2895 (20130101) C10M 2213/046 (20130101) C10M 2213/062 (20130101) C10M 2215/0813 (20130101) C10M 2223/10 (20130101) C10M 2223/103 (20130101) C10M 2229/025 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2210/02 (20130101) C10N 2210/03 (20130101) C10N 2210/04 (20130101) C10N 2210/08 (20130101) C10N 2220/082 (20130101) C10N 2230/06 (20130101) C10N 2230/56 (20130101) C10N 2250/10 (20130101) C10N 2250/14 (20130101) C10N 2270/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100286 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama) |
| ASSIGNEE(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| INVENTOR(S) | Yonghyun Kim (Northport, Alabama); David A. Dozier (Tuscaloosa, Alabama); Ursula L. Triantafillu (Tuscaloosa, Alabama) |
| ABSTRACT | Various implementations include systems and methods for automatically and continuously dissociating spheres of cells. In particular, one such system includes a peristaltic pump in fluid communication via tubing with a bioreactor in which cells are cultivated. A plurality of conduits are disposed within a portion of the tubing such that fluid flowing between the bioreactor and the pump passes through the conduits. The conduits have an inner diameter that is sized to provide a shear stress to the fluid of between about 5 to about 60 dynes/cm2, which is sufficient for dissociating the spheres of cells passing through the conduits. For example, each conduit may have an inner diameter of between about 50 and about 250 micrometers. |
| FILED | Friday, June 19, 2015 |
| APPL NO | 14/744200 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 47/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Original (OR) Class C12N 2509/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100300 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Ohio State University (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ly James Lee (Columbus, Ohio); Pouyan E. Boukany (Columbus, Ohio); Jingjiao Guan (Tallahassee, Florida); Nan-Rong Chiou (Midland, Michigan) |
| ABSTRACT | A simple and low cost method of producing sealed arrays of laterally ordered nanochannels interconnected to microchannels of tunable size, over large surface areas, is disclosed. The method incorporates DNA combing and subsequent imprinting. Associated micro and macroscale inlets and outlets can be formed in the same process or manufactured later in low cost, non-cleanroom techniques. The techniques embrace two procedures, generating DNA nanostrands and translating these strands into nanoscale constructs via imprinting. Devices incorporating the novel arrays have a first microchannel, a second microchannel and a nanochannel that is substantially linear and which defines an axis. The nanochannel is connected at its open ends to the microchannels, which are aligned along the axis. Methods for precise dose delivery of agents into cells employing the devices in nanoelectroporation methods are also disclosed. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809702 |
| ART UNIT | 1799 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Original (OR) Class C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100318 | Babb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jonathan William Babb (Watertown, Massachusetts); Ron Weiss (Newton, Massachusetts); Thomas Knight (Cambridge, Massachusetts); Adam Rubin (Cleveland, Ohio) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jonathan William Babb (Watertown, Massachusetts); Ron Weiss (Newton, Massachusetts); Thomas Knight (Cambridge, Massachusetts); Adam Rubin (Cleveland, Ohio) |
| ABSTRACT | Aspects of the invention relate to reconfigurable chassis that allow for rapid construction and optimization of biocircuits. |
| FILED | Monday, November 15, 2010 |
| APPL NO | 12/946604 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/635 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100411 | Frankiewicz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Christophe Frankiewicz (Boone, Iowa); Daniel Attinger (Ames, Iowa) |
| ABSTRACT | A method is provided for forming a biphilic surface on a substrate comprising copper, such as a heat exchanger surface, wherein the method involves forming one or more hydrophilic areas on the surface by reacting those areas with at least one of hydrogen peroxide and ammonium hydroxide to form copper oxide and forming hydrophobic areas on the surface by reacting those areas with ammonium hydroxide solution to form copper hydroxide or by chemical etching with a combination of hydrochloric acid, hydrogen peroxide, and iron chloride. The functional surface can exhibit temporal biphilicity in response to one or more stimuli in high performance heat transfer applications. |
| FILED | Monday, January 30, 2017 |
| APPL NO | 15/530567 |
| ART UNIT | 3744 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/63 (20130101) Original (OR) Class Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/18 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/003 (20130101) F28F 13/185 (20130101) F28F 2245/02 (20130101) F28F 2245/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100417 | Bocarsly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); Liquid Light, Inc. (Monmouth Junction, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey); Avantium Knowledge Centre B.V. (Amsterdam, Netherlands) |
| INVENTOR(S) | Andrew B. Bocarsly (Plainsboro, New Jersey); Zachary M. Detweiler (Plainsboro, New Jersey) |
| ABSTRACT | A method reducing carbon dioxide to one or more organic products may include steps (A) to (E). Step (A) may introduce an anolyte to a first compartment of an electrochemical cell. The first compartment may include an anode. Step (B) may introduce a catholyte and carbon dioxide to a second compartment of the electrochemical cell. Step (C) may oxidize an indium cathode to produce an oxidized indium cathode. Step (D) may introduce the oxidized indium cathode to the second compartment. Step (E) may apply an electrical potential between the anode and the oxidized indium cathode sufficient for the oxidized indium cathode to reduce the carbon dioxide to a reduced product. |
| FILED | Friday, August 23, 2013 |
| APPL NO | 14/422322 |
| ART UNIT | 1759 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/04 (20130101) Original (OR) Class C25B 9/08 (20130101) C25B 11/04 (20130101) C25B 11/0452 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101147 | Nolte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | David D. Nolte (Lafayette, Indiana); John J. Turek (West Lafayette, Indiana); Kwan Jeong (Seoul, South Korea) |
| ABSTRACT | A system for motility contrast imaging a biological target within tissue comprising a CCD array; an illumination source for generating an incoming beam; a first beam splitter for receiving the incoming beam and producing an object beam and a reference beam; a second beam splitter for illuminating a multitude of biological targets with the object beam and for directing backscattered object beams towards the CCD array; a computer-controlled delay stage for zero-path-matching the reference beam to the backscattered object beams; a reference beam that intersects the backscattered object beams at an angle to produce a series of interference fringes that modulate Fourier-domain information; and a computer for receiving a time series of Fourier-domain information. The interference fringes between the backscattered object beam and the reference beam are recorded by the CCD array and passed to the computer which constructs a digital hologram at successive times. |
| FILED | Monday, November 10, 2014 |
| APPL NO | 14/537496 |
| ART UNIT | 3737 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02032 (20130101) G01B 9/02082 (20130101) G01B 9/02091 (20130101) Original (OR) Class Holographic Processes or Apparatus G03H 1/08 (20130101) G03H 1/0443 (20130101) G03H 2001/045 (20130101) G03H 2001/0445 (20130101) G03H 2001/0467 (20130101) G03H 2210/62 (20130101) G03H 2222/33 (20130101) G03H 2223/20 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101299 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shan X. Wang (Portola Valley, California); Richard S. Gaster (Los Altos, California); Liang Xu (Nanchang, China PRC); Shu-Jen Han (Cortlandt Manor, New York); Robert Wilson (Campbell, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Standford Junior University (Palo Alto, California) |
| INVENTOR(S) | Shan X. Wang (Portola Valley, California); Richard S. Gaster (Los Altos, California); Liang Xu (Nanchang, China PRC); Shu-Jen Han (Cortlandt Manor, New York); Robert Wilson (Campbell, California) |
| ABSTRACT | Methods for quantitatively determining a binding kinetic parameter of a molecular binding interaction are provided. Aspects of embodiments of the methods include: producing a magnetic sensor device including a magnetic sensor in contact with an assay mixture including a magnetically labeled molecule to produce a detectable molecular binding interaction; obtaining a real-time signal from the magnetic sensor; and quantitatively determining a binding kinetics parameter of the molecular binding interaction from the real-time signal. Also provided are systems and kits configured for use in the methods. |
| FILED | Friday, March 11, 2011 |
| APPL NO | 13/046368 |
| ART UNIT | 1677 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) Original (OR) Class G01N 33/557 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101315 | Meller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Amit Meller (Brookline, Massachusetts); Meni Wanunu (West Roxbury, Massachusetts) |
| ABSTRACT | Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof. Nanopores are extremely sensitive single-molecule sensors. Recently, electron beams have been used to fabricate synthetic nanopores in thin solid-state membranes with sub-nanometer resolution. A new class of chemically modified nanopore sensors are provided with two approaches for monolayer coating of nanopores by: (1) self-assembly from solution, in which nanopores −10 nm diameter can be reproductibly coated, and (2) self-assembly under voltage-driven electrolyte flow, in which 5 nm nanopores may be coated. Applications of chemically modified nanopore are provided including: the detection of biopolymers such as DNA and RNA; immobilizing enzymes or other proteins for detection or for generating chemical gradients; and localized pH sensing. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 15/411782 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102319 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Jie Li (Lansing, Michigan); Shanker Balasubramaniam (Okemos, Michigan) |
| ABSTRACT | An iso-geometric analysis technique based on subdivision is presented for boundary integral equations associated with electromagnetics. Subdivision geometry processing has seen rapid growth in the computer graphics community. In terms of geometry processing, subdivision offers several advantages including adaptivity, refinement, smoothness, etc. As a result, these salient features are inherited by physics solvers providing unprecedented accuracy, convergence, low frequency stability, etc. |
| FILED | Friday, July 15, 2016 |
| APPL NO | 15/210972 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5018 (20130101) Original (OR) Class G06F 2217/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102671 | Suresh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Krishnan Suresh (Middleton, Wisconsin); Alireza H. Taheri (Madison, Wisconsin) |
| ABSTRACT | Systems and methods for generating approximations and other representations of data in a data set include a generalized non-uniform rational B-splines (NURBS) framework that facilitates optimized computer-generated representations having high accuracy and requiring less computing resources than previous frameworks capable of achieving similar accuracy. The framework includes a set of rational basis functions that define a mesh parametrization of the data set; these rational basis functions are based on the typical NURBS rational basis functions, but decoupled to provide discrete weights in each direction of a parametrized space. The value of each decoupled weight can be individually altered to improve the accuracy of the representation in the corresponding direction without altering the underlying mesh parametrization. The accuracy and efficiency of the proposed methods, particularly for data sets including discontinuities or localized gradients, is demonstrated through numerical experiments. |
| FILED | Thursday, February 09, 2017 |
| APPL NO | 15/428331 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 17/20 (20130101) G06T 17/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103057 | Abelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John Abelson (Urbana, Illinois); Shaista Babar (Hillsboro, Oregon); Elham Mohimi (Urbana, Illinois); Gregory Girolami (Urbana, Illinois) |
| ABSTRACT | Provided herein are methods for selectively forming layers of metal films on one portion of a substrate while leaving adjacent portions of the substrate uncoated. The methods provide for selectively depositing metal films on a conductive surface, such as ruthenium oxide, disposed on or near an insulating portion of the substrate, such as a silicon dioxide (SiO2) surface. The invention provides methods to simultaneously contact the substrate surface with both the precursor gas and the inhibitor agent leading to the selective formation of metal nuclei on the conductive portion of the substrate. In the methods described, nuclei are selectively formed by a disproportionation reaction occurring on the conductive portion of the substrate but not on the insulating portion of the substrate. |
| FILED | Tuesday, November 10, 2015 |
| APPL NO | 14/937790 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/04 (20130101) C23C 16/18 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/28562 (20130101) H01L 21/76876 (20130101) H01L 21/76879 (20130101) Original (OR) Class H01L 21/76885 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103913 | Pande et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Partha Pande (Pullman, Washington); Deukhyoun Heo (Pullman, Washington) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington) |
| INVENTOR(S) | Partha Pande (Pullman, Washington); Deukhyoun Heo (Pullman, Washington) |
| ABSTRACT | In some embodiments, improved routing strategies for small-world network-on-chip (SWNoC) systems are provided. In some embodiments, an ALASH routing strategy or an MROOTS strategy are used in order to improve latency, temperature, and energy use within a network-on-chip system. In some embodiments, millimeter-wave wireless transceivers are used to implement the long-distance links within the small-world network, to create a millimeter-wave small-world network-on-chip (mSWNoC) system. In some embodiments, non-coherent on-off keying (OOK) wireless transceivers are used to implement the wireless links. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/081524 |
| ART UNIT | 2411 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 1/40 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0331 (20130101) H04L 7/0337 (20130101) H04L 27/0002 (20130101) Original (OR) Class H04L 27/04 (20130101) H04L 27/06 (20130101) H04L 45/12 (20130101) H04L 47/30 (20130101) H04L 49/60 (20130101) H04L 49/109 (20130101) H04L 2012/6421 (20130101) Wireless Communication Networks H04W 40/02 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 70/00 (20180101) Y02D 70/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104195 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey); RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Yingying Chen (Morganville, New Jersey); Jie Yang (Tallahassee, Florida); Yan Wang (Jersey City, New Jersey); Jian Liu (Jersey City, New Jersey); Marco Gruteser (Princeton, New Jersey) |
| ABSTRACT | A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment. |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/074305 |
| ART UNIT | 2472 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/306 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/04 (20130101) H04W 4/027 (20130101) H04W 4/029 (20180201) H04W 84/12 (20130101) H04W 88/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104365 | Banks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TetraVue, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul S. Banks (San Marcos, California); Bodo Schmidt (Carlsbad, California); C. Stewart Tuvey (Carlsbad, California) |
| ABSTRACT | The methods and systems disclosed herein improve upon previous 3D imaging techniques by making use of a longer illumination pulse to obtain the same or nearly the same range resolution as can be achieved by using a much shorter, conventional laser pulse. For example, a longer illumination pulse can be produced by one or more Q-switched lasers that produce, for example, 5, 10, 20 ns or longer pulses. In some instances, the laser pulse can be longer than the modulation waveform of a MIS-type imaging system and still produce a repeatable response function. The light pulse generation technologies required to achieve longer pulse lengths can be significantly less expensive and less complex than known technologies presently used to generate shorter illumination pulse lengths. Lower-cost, lower-complexity light pulse sources may facilitate lower-cost, commercial 3D camera products. |
| FILED | Monday, April 27, 2015 |
| APPL NO | 14/696793 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/499 (20130101) G01S 7/4814 (20130101) G01S 7/4816 (20130101) G01S 17/10 (20130101) G01S 17/89 (20130101) Pictorial Communication, e.g Television H04N 13/0253 (20130101) H04N 13/254 (20180501) Original (OR) Class H04N 13/271 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10098332 | Kirkpatrick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brian Wayne Kirkpatrick (Madison, Wisconsin) |
| ABSTRACT | Described herein are methods and compositions for modulating bovine birth rate by following a breeding scheme based on the presence of the trio haplotype, which is strongly linked to the propensity to give birth to multiple calves in one event. |
| FILED | Tuesday, July 01, 2014 |
| APPL NO | 14/321036 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/02 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/124 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098945 | Palese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee); The United States of America, As Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); St. Jude Children's Research Hospital (Memphis, Tennessee); The United States of America, As Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Richard J. Webby (Memphis, Tennessee); Juergen A. Richt (Ames, Iowa); Robert G. Webster (Memphis, Tennessee); Kelly M. Lager (Colo, Iowa) |
| ABSTRACT | The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated swine influenza viruses having modifications to a swine NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. These viruses replicate in vivo, but demonstrate decreased replication, virulence and increased attenuation, and therefore are well suited for use in live virus vaccines, and pharmaceutical formulations. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/375664 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/552 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16034 (20130101) C12N 2760/16121 (20130101) C12N 2760/16171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10098964 | Donovan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Joseph D. Donovan (Urbana, Illinois); Soo-Yeun Lee (Champaign, Illinois); Youngsoo Lee (Champign, Illinois) |
| ABSTRACT | The invention provides novel formulations comprising a stable inclusion complex of tributyrin and a cyclodextrin. In one particular embodiment, the formulation comprises an oven dried inclusion complex of tributyrin and γ-cyclodextrin that is effective in minimizing or preventing the unpleasant taste and odor of tributyrin, thus making it suitable for oral administration and delivery to the digestive tract and intestines. The invention provides compositions of these inclusion complexes and methods of using them that are advantageous as food, medicinal and other products, where the negative sensory properties of tributyrin can be a liability. |
| FILED | Monday, March 14, 2016 |
| APPL NO | 15/069371 |
| ART UNIT | 1673 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) A23L 33/15 (20160801) A23L 33/16 (20160801) A23L 33/17 (20160801) A23L 33/40 (20160801) A23L 33/155 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/32 (20130101) A23V 2250/1946 (20130101) A23V 2250/5112 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/225 (20130101) A61K 47/48969 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100306 | Inberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Monsanto Technology LLC (St. Louis, Missouri); Beeologics, Inc. (St. Louis, Missouri); The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Monsanto Technology LLC (St. Louis, Missouri) |
| INVENTOR(S) | Alex Inberg (Ballwin, Missouri); Mahak Kapoor (Chesterfield, Missouri); Jay Evans (Harwood, Maryland) |
| ABSTRACT | This application provides and discloses anti-parasitic, anti-pest or insecticidal nucleic acid molecules and their calmodulin target genes for the control of arthropod parasites and pests. This application further provides methods and compositions for the control and treatment of parasites and pests in Apis mellifera (honey bee) hives. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 15/378513 |
| ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 51/00 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 63/02 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100325 | Clemente et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Thomas E. Clemente (Lincoln, Nebraska); Hyunwoo Park (Kyeonggi, South Korea); Edgar Cahoon (Lincoln, Minnesota); Hanh Nguyen (Lincoln, Nebraska) |
| ABSTRACT | Methods of genetically modifying soybean plants to alter the fatty acid properties of the oil are described. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 14/815377 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100373 | Wang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jinbo Wang (Berwyn Heights, Maryland) |
| ABSTRACT | The present invention provides methods and compositions for detecting multiple citrus pathogens using a multiplex branched DNA signal amplification reaction. |
| FILED | Monday, May 23, 2016 |
| APPL NO | 15/162045 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101312 | Shor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Leslie M. Shor (Coventry, Connecticut); Jessica Furrer Chau (Columbia, South Carolina); Daniel J. Gage (Columbia, Connecticut) |
| ABSTRACT | A soil-emulating device and a system for evaluation of soil-related properties are provided. The soil-emulating apparatus includes one or more soil micromodels comprising packed emulated soil particles. The packed soil particles comprise a particle size distribution, and a soil structure of a desired soil type. The soil micromodel is cast from a two-dimensional representation of a region to provide visualization of air infiltration into pores of the micromodel. The soil micromodel is located within an environmental control chamber to control humidity and, optionally, the soil micromodel is saturated with a bacteria strain. Images are captured of the soil micromodel over time. |
| FILED | Wednesday, December 02, 2015 |
| APPL NO | 14/957140 |
| ART UNIT | 1799 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/246 (20130101) Original (OR) Class G01N 2033/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10098414 | Cavanagh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DIAPEDIA, LLC (State College, Pennsylvania); University of Delaware (Newark, Delaware) |
| ASSIGNEE(S) | DIAPEDIA, LLC (State College, Pennsylvania); UNIVERSITY OF DELAWARE (Newark, Delaware) |
| INVENTOR(S) | Peter R. Cavanagh (Seattle, Washington); Timothy B. Hurley (Boalsburg, Pennsylvania); John J. Tierney (Newark, Delaware); John W. Gillespie, Jr. (Hockessin, Delaware) |
| ABSTRACT | The improved footwear system of the present application uses composite materials in the design of an advanced modular in-shoe foot orthosis and a new container assembly which includes a high performance energy storage and return element orthosis. The footwear system uses a method of manufacture incorporating a new last model. The advantages of the footwear system over standard issue combat boots include lower weight, improved treatment of lower extremity overuse injuries and reduction of the occurrence of such overuse injuries by protecting at-risk feet with advanced footwear which can be customized to meet the biomechanical needs as well as the specific activities of the wearer. |
| FILED | Thursday, March 06, 2014 |
| APPL NO | 14/199790 |
| ART UNIT | 3765 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Characteristic Features of Footwear; Parts of Footwear A43B 7/141 (20130101) A43B 7/1445 (20130101) A43B 13/026 (20130101) A43B 13/127 (20130101) A43B 13/141 (20130101) A43B 13/181 (20130101) A43B 13/183 (20130101) A43B 13/386 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100423 | Hall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy D. Hall (Englewood, Ohio); Burhanuddin Kagajwala (Hillsboro, Oregon) |
| ASSIGNEE(S) | FARADAY TECHNOLOGY, INC. (Englewood, Ohio) |
| INVENTOR(S) | Timothy D. Hall (Englewood, Ohio); Burhanuddin Kagajwala (Hillsboro, Oregon) |
| ABSTRACT | A layer of chromium metal is electroplated from trivalent chromium onto an electrically conducting substrate by immersing the substrate and a counter electrode in a electroplating bath and passing a modulated electric current between the electrodes. In one embodiment, the current contains pulses that are cathodic with respect to said substrate and in another embodiment the current contains pulses that are cathodic and pulses that are anodic with respect to said substrate. The cathodic pulses have a duty cycle greater than about 80%. |
| FILED | Friday, August 14, 2015 |
| APPL NO | 14/826971 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/06 (20130101) C25D 3/10 (20130101) C25D 5/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10103918 | Terry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John David Terry (Annandale, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John David Terry (Annandale, Virginia) |
| ABSTRACT | The present invention teaches a system and method for signal recovery for range and coverage extension in a heterogeneous cooperative network of digital chaos transmissions with OFDM component signal transmission. The invention improves upon the state of art in side channel information from the transmit side containing information on the clipped amplitude. In-band transmission of the side information is achieved by exploiting the sparsity of the resulting clip amplitude position in conjunction with hash function to map keys to values, where the values at the position location for the clipped amplitude. The information rate of the clipped amplitude is sub-Nyquist relative to the original OFDM component signal transmission, which allows very low power spreading by a cooperative digital chaos sequences at a transmit side and recovery of the clipped amplitude at a receive side. Further, an improved noise resistance side channel performance is achieved by mapping to clipping amplitudes to scaled digital chaos samples preloaded on the receive device. A network manager or coordinator can update these scaled digital chaos samples during scheduled beacon frames to improvement network performance. |
| FILED | Thursday, February 02, 2017 |
| APPL NO | 15/422468 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0044 (20130101) H04L 27/2623 (20130101) Original (OR) Class H04L 27/2627 (20130101) Wireless Communication Networks H04W 4/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10098560 | Narayan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Topera, Inc. (Menlo Park, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sanjiv Narayan (La Jolla, California); Carey Robert Briggs (La Jolla, California); Ruchir Sehra (Scottsdale, Arizona) |
| ABSTRACT | A system and method are provided to define a driver of a source associated with a cardiac rhythm disorder of a human heart. A plurality of cardiac signals associated with sensors arranged spatially in relation to an area of the heart are processed to determine a sequence of arcs of rotation in relation to the sensors over a time interval. Rotational directions of the arcs of rotation in the sequence are determined. The area of the heart is identified as controlling the source when the rotational directions of the arcs of rotation in the sequence continue in a same rotational direction in excess of a threshold. |
| FILED | Tuesday, September 29, 2015 |
| APPL NO | 14/869687 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/046 (20130101) A61B 5/0422 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10101454 | Pearlman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States of America as represented by the Department of Veterans Affair (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan L. Pearlman (Pittsburgh, Pennsylvania); Eric Joseph Sinagra (Pittsburgh, Pennsylvania); Jonathan Aaron Duvall (Pittsburgh, Pennsylvania); Joshua D. Brown (Pittsburgh, Pennsylvania); Dianna Rae Stuckey (Butler, Pennsylvania); Tianyang Chen (Shanghai, China PRC); Ian Patrick McIntyre (Holland, Pennsylvania); Rory Alan Cooper (Gibsonia, Pennsylvania) |
| ABSTRACT | A pathway measurement system hereof includes a rigid frame and a mobility system attached to the frame. The mobility system includes at least one movable element which is adapted to contact a surface of a pathway via which the frame may be moved relative to the pathway. The pathway measurement system further includes at least one sensor adapted to measure at least one characteristic of a pathway. The pathway measurement system has a first mode of operation in which the mobility system moves the frame along the pathway to move the at least one sensor relative to the pathway. The at least one sensor is connected to the pathway system such that a distance between the at least one sensor and an axis of rotation of one of the moveable elements remains constant in the first mode of operation. In general, the at least one sensor is isolated from any compliance or suspension system. |
| FILED | Thursday, January 15, 2015 |
| APPL NO | 14/597721 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 7/04 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4813 (20130101) G01S 17/023 (20130101) G01S 17/42 (20130101) Original (OR) Class G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 10099981 | Ferreira et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Eric Ferreira (Athens, Georgia); Qiankun Li (Taihe, China PRC) |
| ABSTRACT | Provided are methods for the meta-selective C—H arylations of arene alcohol-based substrates. The methods combine the transient norbornene strategy with a quinoline-based acetal scaffold to achieve the formation of biaryl compounds. These processes establish a foundation for catalytic polyfunctionalization of alcohol-based compounds. The method comprises attaching a heterocyclic hemiacetal scaffold to an aromatic alcohol or a substituted aromatic alcohol; reacting the aromatic or substituted aromatic alcohol having the heterocyclic hemiacetal scaffold attached with an alkyl or aryl iodide in a reaction mix comprising a palladium catalyst, a silver salt, and carboxymethyl norbornene to generate a meta-arylated arene conjugated to the heterocyclic hemiacetal scaffold; and then cleaving the heterocyclic hemiacetal scaffold from the meta-arylated arene alcohol. |
| FILED | Friday, November 10, 2017 |
| APPL NO | 15/809305 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 41/18 (20130101) Original (OR) Class C07C 41/28 (20130101) C07C 41/28 (20130101) C07C 43/23 (20130101) C07C 45/64 (20130101) C07C 45/64 (20130101) C07C 45/673 (20130101) C07C 49/84 (20130101) C07C 67/31 (20130101) C07C 67/31 (20130101) C07C 67/31 (20130101) C07C 67/31 (20130101) C07C 67/333 (20130101) C07C 69/76 (20130101) C07C 69/94 (20130101) C07C 69/734 (20130101) C07C 201/12 (20130101) C07C 201/12 (20130101) C07C 205/37 (20130101) C07C 269/06 (20130101) C07C 269/06 (20130101) C07C 271/28 (20130101) C07C 2603/86 (20170501) Heterocyclic Compounds C07D 209/08 (20130101) C07D 317/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100423 | Hall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy D. Hall (Englewood, Ohio); Burhanuddin Kagajwala (Hillsboro, Oregon) |
| ASSIGNEE(S) | FARADAY TECHNOLOGY, INC. (Englewood, Ohio) |
| INVENTOR(S) | Timothy D. Hall (Englewood, Ohio); Burhanuddin Kagajwala (Hillsboro, Oregon) |
| ABSTRACT | A layer of chromium metal is electroplated from trivalent chromium onto an electrically conducting substrate by immersing the substrate and a counter electrode in a electroplating bath and passing a modulated electric current between the electrodes. In one embodiment, the current contains pulses that are cathodic with respect to said substrate and in another embodiment the current contains pulses that are cathodic and pulses that are anodic with respect to said substrate. The cathodic pulses have a duty cycle greater than about 80%. |
| FILED | Friday, August 14, 2015 |
| APPL NO | 14/826971 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/06 (20130101) C25D 3/10 (20130101) C25D 5/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10100858 | Jung-Kubiak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Cecile Jung-Kubiak (Pasadena, California); Theodore Reck (Pasadena, California); Bertrand Thomas (Bonn, Germany); Robert H. Lin (Chino, California); Alejandro Peralta (Huntington Beach, California); John J. Gill (La Crescenta, California); Choonsup Lee (La Palma, California); Jose V. Siles (Pasadena, California); Risaku Toda (Glendale, California); Goutam Chattopadhyay (Pasadena, California); Ken B. Cooper (Glendale, California); Imran Mehdi (South Pasadena, California) |
| ABSTRACT | A silicon alignment pin is used to align successive layer of component made in semiconductor chips and/or metallic components to make easier the assembly of devices having a layered structure. The pin is made as a compressible structure which can be squeezed to reduce its outer diameter, have one end fit into a corresponding alignment pocket or cavity defined in a layer of material to be assembled into a layered structure, and then allowed to expand to produce an interference fit with the cavity. The other end can then be inserted into a corresponding cavity defined in a surface of a second layer of material that mates with the first layer. The two layers are in registry when the pin is mated to both. Multiple layers can be assembled to create a multilayer structure. Examples of such devices are presented. |
| FILED | Friday, October 28, 2016 |
| APPL NO | 15/337745 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/025 (20130101) Original (OR) Class F16B 19/004 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 13/0015 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49778 (20150115) Y10T 29/49895 (20150115) Y10T 403/20 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102756 | Burke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of Americ as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Kelly Ann Burke (Virginia Beach, Virginia); David J. Wing (Hampton, Virginia); Joseph G. Ponthieux (Yorktown, Virginia); Sharon Woods (Ayer, Massachusetts); Stephen DePascale (Tyngsboro, Massachusetts) |
| ABSTRACT | Systems and methods of an in-cockpit flight trajectory modification system for an aircraft are provided. A receiver is capable of receiving flight-related hazard information. A traffic aware planner (TAP) module is operably connected to the receiver to receive the flight-related hazard information. A user interface device is operably connected to the TAP module on board the aircraft to provide trajectory information associated with the aircraft and to receive user input corresponding to a request for a revised trajectory. A TAP application is capable of calculating one or more revised trajectories for the aircraft based at least on active trajectory information of the aircraft and the flight-related hazard information. The user interface device may be configured to display information related to the one or more revised trajectories, including a graphic display of the active trajectory and at least one revised trajectory in a visualization panel of the user interface device. |
| FILED | Wednesday, September 30, 2015 |
| APPL NO | 14/871362 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Traffic Control Systems G08G 5/006 (20130101) G08G 5/0008 (20130101) G08G 5/0013 (20130101) Original (OR) Class G08G 5/0021 (20130101) G08G 5/0039 (20130101) G08G 5/0056 (20130101) G08G 5/0078 (20130101) G08G 5/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10101786 | Eastep et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Jonathan M. Eastep (Portland, Oregon); Richard J. Greco (West Linn, Oregon) |
| ABSTRACT | Methods and apparatus to provide holistic global performance and power management are described. In an embodiment, logic (e.g., coupled to each compute node of a plurality of compute nodes) causes determination of a policy for power and performance management across the plurality of compute nodes. The policy is coordinated across the plurality of compute nodes to manage a job to one or more objective functions, where the job includes a plurality of tasks that are to run concurrently on the plurality of compute nodes. Other embodiments are also disclosed and claimed. |
| FILED | Monday, December 22, 2014 |
| APPL NO | 14/580150 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 1/189 (20130101) G06F 1/3203 (20130101) Original (OR) Class G06F 9/4893 (20130101) G06F 9/5094 (20130101) Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10102124 | Steely, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Simon C. Steely, Jr. (Hudson, New Hampshire); William C. Hasenplaugh (Boston, Massachusetts); Joel S. Emer (Hudson, Massachusetts); Samantika Subramaniam (Westford, Massachusetts) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Simon C. Steely, Jr. (Hudson, New Hampshire); William C. Hasenplaugh (Boston, Massachusetts); Joel S. Emer (Hudson, Massachusetts); Samantika Subramaniam (Westford, Massachusetts) |
| ABSTRACT | A micro-architecture may provide a hardware and software of a high bandwidth write command. The micro-architecture may invoke a method to perform the high bandwidth write command. The method may comprise sending a write request from a requester to a record keeping structure. The write request may have a memory address of a memory that stores requested data. The method may further determine copies of the requested data being present in a distributed cache system outside the memory, sending invalidation requests to elements holding copies of the requested data in the distributed cache system, sending a notification to the requester to inform presence of copies of the requested data and sending a write response message after a latest value of the requested data and all invalidation acknowledgements have been received. |
| FILED | Wednesday, December 28, 2011 |
| APPL NO | 13/993716 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0808 (20130101) Original (OR) Class G06F 13/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10098333 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Songtao Shi (Irvine, California); Takayoshi Yamaza (Pasadena, California); Kentaro Akiyama (Fukuoka, Japan) |
| ASSIGNEE(S) | University Of Southern California (Los Angeles, California) |
| INVENTOR(S) | Songtao Shi (Irvine, California); Takayoshi Yamaza (Pasadena, California); Kentaro Akiyama (Fukuoka, Japan) |
| ABSTRACT | This invention discloses a stem cell modified animal model useful as a research tool for investigating aging-related degeneration processes and treatments. The animal model is preferably a rodent subcutaneously transplanted with a mesenchymal stem cell capable of generating a functional bone or marrow element. Also provided are a method for extending the lifespan and improving the quality of life of a subject by subcutaneously transplanting a plurality of mesenchymal stem cells to the subject, wherein the mesenchymal stem cells are capable of generating a functional bone or marrow element. Compositions and source of stem cells suitable for use with the methods of this invention, including stem cells from human exfoliated deciduous teeth (SHED), are also disclosed. Further disclosed is a method for identifying progenitor bone marrow mesenchymal stem cells, and a method for treating SLE-like autoimmune diseases by infusion of mesenchymal stem cells. |
| FILED | Wednesday, December 09, 2009 |
| APPL NO | 13/133638 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class A01K 2227/105 (20130101) A01K 2267/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10100279 | Nicholas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Cory R. Nicholas (San Francisco, California); John L. Rubenstein (San Francisco, California); Arnold R. Kriegstein (Mill Valley, California); Arturo Alvarez-Buylla (Woodside, California) |
| ABSTRACT | Methods and systems for generating MGE precursor cells in vitro as well as compositions of enriched MGE precursor cells are provided. The methods and systems provide efficient production of MGE precursors. The methods and systems disclosed herein provide functional MGE precursors which differentiate into functional GABAergic interneurons. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/763397 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0618 (20130101) Original (OR) Class C12N 5/0619 (20130101) C12N 2500/90 (20130101) C12N 2501/13 (20130101) C12N 2501/41 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 10101278 | Blair |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Richard George Blair (Oviedo, Florida) |
| ABSTRACT | A portable spectrometer system is disclosed for more reliable and convenient on-site drug testing. More particularly, but not by way of limitation, the presently disclosed and/or claimed inventive concept(s) relates to a portable spectrometer system having a test strip having a fluorescent indicator, a fluorimeter, and a mobile computing device capable of determining the identity of an unknown substance in the sample. |
| FILED | Friday, May 09, 2014 |
| APPL NO | 14/889318 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/77 (20130101) Original (OR) Class G01N 21/255 (20130101) G01N 21/645 (20130101) G01N 2021/7786 (20130101) G01N 2201/061 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 10100356 | Esfandyarpour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GenapSys, Inc. (Redwood City, California) |
| ASSIGNEE(S) | GENAPSYS, INC. (Redwood City, California) |
| INVENTOR(S) | Hesaam Esfandyarpour (Redwood City, California); Mark F. Oldham (Emerald Hills, California); Kosar Baghbani Parizi (Los Altos, California); Eric S. Nordman (Palo Alto, California) |
| ABSTRACT | A method comprises magnetically holding a bead carrying biological material (e.g., nucleic acid, which may be in the form of DNA fragments or amplified DNA) in a specific location of a substrate, and applying an electric field local to the bead to isolate the biological material or products or byproducts of reactions of the biological material. For example, the bead isolated from other beads having associated biological material. The electric field in various embodiments concentrates reagents for an amplification or sequencing reaction, and/or concentrates and isolates detectable reaction by-products. For example, by isolating nucleic acids around individual beads, the electric field can allow for clonal amplification, as an alternative to emulsion PCR. In other embodiments, the electric field isolates a nanosensor proximate to the bead, to facilitate detection of at least one of local pH change, local conductivity change, local charge concentration change and local heat. The beads may be trapped in the form of an array of localized magnetic field regions. |
| FILED | Monday, September 21, 2015 |
| APPL NO | 14/859725 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/10 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2200/0689 (20130101) B01L 2300/12 (20130101) B01L 2300/089 (20130101) B01L 2300/123 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) B01L 2400/0415 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) B01L 2400/0424 (20130101) B01L 2400/0427 (20130101) B01L 2400/0478 (20130101) B01L 2400/0655 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/30 (20130101) B03C 1/286 (20130101) B03C 1/288 (20130101) B03C 5/005 (20130101) B03C 5/022 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2523/307 (20130101) C12Q 2563/116 (20130101) C12Q 2563/116 (20130101) C12Q 2563/143 (20130101) C12Q 2563/143 (20130101) C12Q 2565/543 (20130101) C12Q 2565/543 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/40 (20130101) G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/5438 (20130101) G01N 2001/4038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 10101466 | Yilmaz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alper Yilmaz (Lewis Center, Ohio); Ashish Gupta (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Alper Yilmaz (Lewis Center, Ohio); Ashish Gupta (Columbus, Ohio) |
| ABSTRACT | According to the embodiments provided herein, a trajectory determination device for geo-localization can include one or more relative position sensors, one or more processors, and memory. The one or more processors can execute machine readable instructions to receive the relative position signals from the one or more relative position sensors. The relative position signals can be transformed into a sequence of relative trajectories. Each of the relative trajectories can include a distance and directional information indicative of a change in orientation of the trajectory determination device. A progressive topology can be created based upon the sequence of relative trajectories; this progressive topology can be compared to map data. A geolocation of the trajectory determination device can be determined. |
| FILED | Friday, February 19, 2016 |
| APPL NO | 15/048285 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/26 (20130101) G01S 19/45 (20130101) G01S 19/51 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 16, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
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https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20181016.html
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