FedInvent™ Patents
Patent Details for Tuesday, October 23, 2018
This page was updated on Monday, March 27, 2023 at 05:38 AM GMT
Department of Health and Human Services (HHS)
| US 10104882 | LoPachin et al. |
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| FUNDED BY |
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| APPLICANT(S) | MONTEFIORE MEDICAL CENTER (Bronx, New York) |
| ASSIGNEE(S) | Montefiore Medical Center (Bronx, New York) |
| INVENTOR(S) | Richard M. LoPachin (New Rochelle, New York); Terrence Gavin (New Paltz, New York) |
| ABSTRACT | Methods and compositions using 1,3-dicarbonyl compounds are disclosed for treating toxicity due to therapeutic agents and agents that causes oxidative cellular damage and for treating liver ischemia-reperfusion injury, as well as diseases and disorders that are improved through administration of N-acetylcysteine. |
| FILED | Monday, April 28, 2014 |
| APPL NO | 14/785861 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/05 (20130101) A61K 31/20 (20130101) A61K 31/20 (20130101) A61K 31/121 (20130101) A61K 31/121 (20130101) A61K 31/122 (20130101) A61K 31/122 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/341 (20130101) A61K 31/341 (20130101) A61K 31/365 (20130101) A61K 31/365 (20130101) A61K 31/366 (20130101) A61K 31/366 (20130101) A61K 31/381 (20130101) A61K 31/381 (20130101) A61K 31/675 (20130101) A61K 31/675 (20130101) A61K 31/4015 (20130101) A61K 31/4015 (20130101) A61K 31/4365 (20130101) A61K 31/4365 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10104888 | Reed et al. |
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| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Jess Dreher Reed (Madison, Wisconsin); Christian Gerald Krueger (Cambridge, Wisconsin); Sergio Madrigal-Carballo (Madison, Wisconsin) |
| ABSTRACT | The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 15/380754 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/16 (20130101) A01N 25/28 (20130101) A01N 43/16 (20130101) Original (OR) Class A01N 43/16 (20130101) A01N 43/16 (20130101) A01N 43/16 (20130101) A01N 43/24 (20130101) A01N 2300/00 (20130101) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2250/21166 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2013/00523 (20130101) A61F 2013/00676 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/008 (20130101) A61K 9/12 (20130101) A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/122 (20130101) A61K 9/1273 (20130101) A61K 9/2013 (20130101) A61K 9/2054 (20130101) A61K 9/5123 (20130101) A61K 9/5161 (20130101) A61K 9/7007 (20130101) A61K 31/351 (20130101) A61K 31/353 (20130101) A61K 31/366 (20130101) A61K 31/715 (20130101) A61K 31/715 (20130101) A61K 31/722 (20130101) A61K 39/0005 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 47/36 (20130101) A61K 47/55 (20170801) A61K 49/227 (20130101) A61K 2039/542 (20130101) A61K 2039/55583 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/085 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) Derivatives of Natural Macromolecular Compounds C08H 6/00 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105062 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Lihong Wang (St. Louis, Missouri); Konstantin Maslov (St. Louis, Missouri); Joon-Mo Yang (St. Louis, Missouri) |
| ABSTRACT | A reflection-mode photoacoustic endoscope includes a tube, a light source configured to emit a light pulse suitable for photoacoustic imaging, an ultrasonic transducer configured to detect a response signal, and a light and acoustic reflector rotatable relative to the tube. |
| FILED | Thursday, April 28, 2016 |
| APPL NO | 15/141189 |
| ART UNIT | 3737 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/0062 (20130101) A61B 5/0068 (20130101) A61B 5/0084 (20130101) A61B 5/0095 (20130101) Original (OR) Class A61B 5/0873 (20130101) A61B 8/12 (20130101) A61B 8/4461 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105186 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Alexis Cheng (Baltimore, Maryland); Emad M. Boctor (Baltimore, Maryland); Xiaoyu Guo (Baltimore, Maryland) |
| ABSTRACT | A virtual rigid body optical tracking system includes a virtual rigid body generator for projecting a virtual rigid body, wherein the virtual rigid body forms a pattern of light on a surface. The virtual rigid body optical tracking system includes an optical detection system for detecting the pattern of light, and a data processing system in communication with the optical detection system. The data processing system is configured to determine a position of the virtual rigid body generator based on the detected pattern of light. |
| FILED | Tuesday, June 09, 2015 |
| APPL NO | 14/734778 |
| ART UNIT | 3737 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/20 (20160201) Original (OR) Class A61B 90/50 (20160201) A61B 2010/045 (20130101) A61B 2017/3413 (20130101) A61B 2018/00577 (20130101) A61B 2034/2055 (20160201) A61B 2034/2057 (20160201) A61B 2034/2065 (20160201) A61B 2090/378 (20160201) A61B 2090/3945 (20160201) A61B 2090/3983 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2025/0166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105208 | Tranquillo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Robert Tranquillo (Arden Hills, Minnesota); Zeeshan Syedain (Minneapolis, Minnesota); Lee Meier (Minneapolis, Minnesota) |
| ABSTRACT | This disclosure describes decellularized, biologically-engineered tubular grafts and methods of making and using such decellularized, biologically-engineered tubular grafts. |
| FILED | Friday, February 27, 2015 |
| APPL NO | 14/633268 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/04 (20130101) A61F 2/06 (20130101) Original (OR) Class A61F 2/062 (20130101) A61F 2/2412 (20130101) A61F 2/2415 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/36 (20130101) A61L 27/507 (20130101) A61L 27/3604 (20130101) A61L 27/3633 (20130101) A61L 27/3695 (20130101) A61L 2430/40 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105263 | Greenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Second Sight Medical Products, Inc. (San Fernando, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert Greenberg (Los Angeles, California); Kelly H McClure (Simi Valley, California); Arup Roy (Valencia, California) |
| ABSTRACT | A visual prosthesis apparatus and a method for limiting power consumption in a visual prosthesis apparatus. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit associated with the camera, the video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured to stop stimulating neural tissue in a subject's eye based on the stimulation patterns when an error is detected in a forward telemetry received from the video processing unit. |
| FILED | Friday, December 07, 2012 |
| APPL NO | 13/707984 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/08 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3787 (20130101) A61N 1/36046 (20130101) A61N 1/37276 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 11/10 (20130101) Pictorial Communication, e.g Television H04N 5/2254 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105305 | Garza et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Luis Andres Garza (Baltimore, Maryland); Amanda Marie Nelson (Hummelstown, Pennsylvania) |
| ABSTRACT | The present invention relates to the field of wound healing. Specifically, the present invention provides compositions and methods for promoting skin regeneration, more specifically, the generation of de novo hair follicles. In one embodiment, a method for stimulating hair follicle neogenesis in a subject comprises the step of administering to the subject an effective amount of a TLR3 agonist. In certain embodiments, the TLR3 agonist is a double stranded RNA (dsRNA). The present invention is also directed to treating common male pattern hair loss. |
| FILED | Thursday, February 19, 2015 |
| APPL NO | 15/120189 |
| ART UNIT | 1676 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/64 (20130101) A61K 8/606 (20130101) Original (OR) Class A61K 31/713 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 7/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) C12N 15/1138 (20130101) C12N 2310/17 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105329 | Garrett et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Wendy S. Garrett (Brookline, Massachusetts); Patrick M. Smith (Foxborough, Massachusetts) |
| ABSTRACT | Disclosed herein are compositions and methods that are useful for inducing the development of regulatory T cells (Treg). Such compositions and methods are useful for treating inflammatory conditions and in particular inflammatory conditions affecting the gastrointestinal tract of a subject. In certain embodiments, the present inventions generally relate to short chain fatty acids and the discovery that such short chain fatty acids may be used to treat and/or prevent inflammatory conditions by enhancing the size and immune function of a subject's endogenous Treg population. |
| FILED | Thursday, June 22, 2017 |
| APPL NO | 15/630766 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105334 | Giannoukakis et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Duquesne University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Duquesne University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Nick Giannoukakis (Coraopolis, Pennsylvania); Massimo M. Trucco (Pittsburgh, Pennsylvania); Wilson S. Meng (Sewickley, Pennsylvania) |
| ABSTRACT | Particle formulations are disclosed that include polymeric particles containing a small molecule drug and a high molecular weight therapeutic protein. Methods of making and using the particle formulations also are disclosed. These particle formulations are of use to treat an autoimmune disease, such as diabetes, or an inflammatory disease. |
| FILED | Friday, January 16, 2015 |
| APPL NO | 15/112152 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/167 (20130101) A61K 9/5031 (20130101) A61K 9/5089 (20130101) A61K 31/203 (20130101) Original (OR) Class A61K 31/203 (20130101) A61K 38/1841 (20130101) A61K 38/1841 (20130101) A61K 45/06 (20130101) A61K 47/48246 (20130101) A61K 47/48861 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105345 | Reed et al. |
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| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Jess Dreher Reed (Madison, Wisconsin); Dhanansayan Shanmuganayagam (Madison, Wisconsin); Christian Gerald Krueger (Cambridge, Wisconsin); Kenneth Allan Kudsk (Madison, Wisconsin); Joseph Francis Pierre (Chicago, Illinois); Aaron F. Heneghan (Middleton, Wisconsin); Rodrigo P. Feliciano (Düsseldorf, Germany) |
| ABSTRACT | Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition. |
| FILED | Wednesday, November 09, 2016 |
| APPL NO | 15/347204 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) A23L 33/17 (20160801) A23L 33/40 (20160801) A23L 33/115 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0029 (20130101) A61K 31/353 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105350 | Paik et al. |
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| FUNDED BY |
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| APPLICANT(S) | David Choohyun Paik (Cheltenham, Pennsylvania); Stephen Lewis Trokel (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | David Choohyun Paik (Cheltenham, Pennsylvania); Stephen Lewis Trokel (New York, New York) |
| ABSTRACT | A method of cross-linking collagen present in a collagenous tissue comprising contacting the collagenous tissue with an amount of a formaldehyde releasing agent effective to crosslink the collagen is provided. A method of inhibiting loss of structural integrity of a collagenous tissue during transplantation-related transport comprising contacting the collagenous tissue with an amount of a formaldehyde releasing agent effective to inhibit loss of structural integrity of the collagenous tissue is also provided. A composition for ophthalmic administration comprising a formaldehyde releasing agent, sodium bicarbonate, and ophthalmically suitable carriers or excipients is also provided. Finally, a method of altering the refractive power of a cornea comprising contacting the cornea with a formaldehyde releasing agent so as to effect cross-linking in the cornea and thereby alter the refractive power of the cornea is provided. |
| FILED | Thursday, March 12, 2015 |
| APPL NO | 15/125558 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/115 (20130101) A61K 31/115 (20130101) A61K 31/4166 (20130101) Original (OR) Class A61K 31/4178 (20130101) A61K 31/4178 (20130101) A61K 33/00 (20130101) A61K 33/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105391 | Wu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Chia-Yung Wu (San Francisco, California); James Onuffer (Alameda, California); Wendell A. Lim (San Francisco, California) |
| ABSTRACT | The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided. |
| FILED | Wednesday, November 01, 2017 |
| APPL NO | 15/801133 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 47/6891 (20170801) A61K 2039/505 (20130101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70575 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2803 (20130101) C07K 16/2866 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/20 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/14 (20130101) C12N 9/90 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 502/01008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105396 | Prockop et al. |
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| FUNDED BY |
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| APPLICANT(S) | Darwin J. Prockop (Philadelphia, Pennsylvania); Joo Youn Oh (Seoul, South Korea); Barry Berkowitz (Framingham, Massachusetts); Gavin W. Roddy (Rochester, Minnesota); Robert Rosa (Holland, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); Temple Therapeutics, Inc. (Framingham, Massachusetts) |
| INVENTOR(S) | Darwin J. Prockop (Philadelphia, Pennsylvania); Joo Youn Oh (Seoul, South Korea); Barry Berkowitz (Framingham, Massachusetts); Gavin W. Roddy (Rochester, Minnesota); Robert Rosa (Holland, Texas) |
| ABSTRACT | The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal. |
| FILED | Monday, June 26, 2017 |
| APPL NO | 15/632633 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 39/00 (20130101) A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) Peptides C07K 16/18 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 2501/25 (20130101) C12N 2501/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105420 | Kadoch et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Cigall Kadoch (Tiburon, California); Gerald R. Crabtree (Woodside, California) |
| ABSTRACT | Methods and compositions are provided for treating human synovial sarcoma (SS). Also provided are screens to identify therapeutics for the treatment of synovial sarcoma. These methods, compositions, and screens are based on the discovery that promoting the assembly of wild type BAF (also called mSWI/SNF) complexes in SS cells by increasing levels of wild type SS18 and/or decreasing levels of SS18-SSX fusion protein leads to the cessation of proliferation of malignant cells in synovial sarcoma. |
| FILED | Wednesday, July 20, 2016 |
| APPL NO | 15/215284 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/661 (20130101) A61K 31/7105 (20130101) A61K 38/17 (20130101) A61K 38/46 (20130101) Original (OR) Class A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57407 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105433 | Chandran et al. |
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| FUNDED BY |
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| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine, Inc. (Bronx, New York) |
| INVENTOR(S) | Kartik Chandran (Brooklyn, New York); Thijin R. Brummelkamp (Amsterdam, Netherlands); Lucas T. Jae (Amsterdam, Netherlands); Rohit K. Jangra (Bronx, New York) |
| ABSTRACT | Methods and assays are disclosed for treating a subject with a hantavirus infection using an agent that binds to protocadherin-1 (PCDH1) or inhibits expression of protocadherin-1 (PCDH1). |
| FILED | Wednesday, February 25, 2015 |
| APPL NO | 15/118504 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7084 (20130101) A61K 31/7105 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2121/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/15 (20130101) G01N 33/53 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105446 | Gmeiner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina) |
| INVENTOR(S) | William H. Gmeiner (Yadkinville, North Carolina) |
| ABSTRACT | Provided herein are aptamers and pharmaceutical compositions comprising the same. In some embodiments, the aptamer selectively binds a protein of interest such as an extracellular receptor protein of interest (e.g., a cancer cell extracellular receptor protein, which may be differentially expressed in some embodiments). In some embodiments, the aptamer is directly linked by covalent bonding (e.g., via a geminal diamine linkage) to from 2 to 10 toxin compounds. Also provided herein is a method of selecting an aptamer that specifically binds to a protein expressed by a cell of interest, wherein in some embodiments the aptamer comprises at least one binding site for one or more active compounds. In some embodiments, primer regions flanking the variable region of the aptamers in the pool contains from 1 to 10 mismatches with respect to said forward or reverse primer. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/285916 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/704 (20130101) A61K 31/7048 (20130101) A61K 47/48092 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/351 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105453 | Mendell et al. |
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| FUNDED BY |
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| APPLICANT(S) | NATIONWIDE CHILDREN'S HOSPITAL, INC. (Columbus, Ohio) |
| ASSIGNEE(S) | NATIONWIDE CHILDREN'S HOSPITAL, INC. (Columbus, Ohio) |
| INVENTOR(S) | Jerry R. Mendell (Columbus, Ohio); Louis Chicoine (Westerville, Ohio); Louise Rodino-Klapac (Groveport, Ohio); Kelly Reed Clark (Columbus, Ohio); Thomas J. Preston (Groveport, Ohio) |
| ABSTRACT | The present invention relates to recombinant adeno-associated virus (rAAV) delivery of an alpha-sarcoglycan gene. The invention provides rAAV products and methods of using the rAAV in the treatment of limb girdle muscular dystrophies such as LGMD2D. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/255295 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 48/0058 (20130101) Original (OR) Class A61K 48/0066 (20130101) A61K 48/0075 (20130101) Peptides C07K 14/4707 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105455 | Duvall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Craig L. Duvall (Nashville, Tennessee); Lawrence J. Marnett (Nashville, Tennessee); Jashim Uddin (Nashville, Tennessee); Thomas A. Werfel (Nashville, Tennessee); Mukesh Gupta (Nashville, Tennessee); Brenda C. Crews (Nashville, Tennessee) |
| ABSTRACT | Disclosed are compositions that comprise a cyclooxygenase-2-selective therapeutic and/or diagnostic agent having a therapeutic and/or diagnostic agent conjugated to a NSAID drug; and a ROS-responsive nanoparticle. Methods of making and using these compositions for drug encapsulation and delivery are also disclosed. |
| FILED | Monday, July 11, 2016 |
| APPL NO | 15/206798 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5146 (20130101) A61K 47/34 (20130101) A61K 49/0041 (20130101) A61K 49/0052 (20130101) Original (OR) Class A61K 49/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105456 | Harmsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Stefan Harmsen (New York, New York); Matthew Wall (New York, New York); Moritz Kircher (New York, New York) |
| ABSTRACT | The present disclosure, among other things, provides a composition of a particle including a substrate; at least a first condensation layer comprising at least a first dopant entity; and at least a second layer comprising a second dopant entity. In some embodiments, different dopant entities are included in different layers. In some embodiments, such dopant entities are or comprise detectable entities. This, in some embodiments, provided technologies achieve multi-modality particles. Among the many advantages of provided technologies include the ability to image particles by a plurality of distinct imaging modalities and/or in a plurality of contexts (e.g., pre-surgical, intraoperative and/or post-surgical environments). The present invention provides methods that include a single administration of particles to a subject, followed by a plurality of steps that comprise imaging the administered particles, which steps may utilize different imaging technologies and/or be performed at different times and/or in different environments. |
| FILED | Thursday, December 19, 2013 |
| APPL NO | 14/653177 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0093 (20130101) Original (OR) Class A61K 49/1824 (20130101) A61K 51/1244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105700 | Konstantopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Konstantinos Konstantopoulos (Ellicott City, Maryland); Colin Dowlin Paul (Catonsville, Maryland); Alfredo Quinones-Hinojosa (Bel Air, Maryland); Aikaterini Kontrogianni-Konstantopoulos (Ellicott City, Maryland) |
| ABSTRACT | The present invention describes an integrated apparatus that enables identification of migratory cells directly from a specimen. The apparatus only requires a small number of cells to perform an assay and includes novel topographic features which can reliably differentiate between migratory and non-migratory cell populations in a sample. Both the spontaneous and chemotactic migration of cancer cells may be measured to distinguish between subpopulations within a tumor sample. The migratory cells identified using the apparatus and methods of the present invention may be separated and further analyzed to distinguish factors promoting metastasis within the population. Cells in the apparatus can be treated with chemotherapeutic or other agents to determine drug strategies to most strongly inhibit migration. The use of optically transparent materials in some embodiments allows a wide range of imaging techniques to be used for in situ imaging of migratory and non-migratory cells in the apparatus. The apparatus and methods of the present invention are useful for predicting the metastatic propensity of tumor cells and selecting optimal drugs for personalized therapies. |
| FILED | Tuesday, July 15, 2014 |
| APPL NO | 14/906055 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 2200/10 (20130101) B01L 2200/027 (20130101) B01L 2200/0652 (20130101) B01L 2200/0689 (20130101) B01L 2300/12 (20130101) B01L 2300/041 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0887 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5029 (20130101) G01N 33/5091 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105712 | Garcia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Maurice M. Garcia (San Francisco, California); Aaron Ohta (Honolulu, Hawaii); Ming Wu (Moraga, California); Tom F. Lue (Hillsborough, California); Justin Valley (Berkeley, California) |
| ABSTRACT | An optical pattern-driven light induced dielectrophoresis (DEP) apparatus and separation methods are described which provide for the manipulation of particles or cells and selection based on traits correlated with the DEP response. Embodiments of the apparatus use DEP electric field patterns in combination with microfluidic laminar flows to measure response, separate, segregate and extract particles from heterogeneous mixtures according to the relative response of the particles to one or more DEP fields without damaging living cells. The preferred OET-DEP devices generally comprise a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a localized virtual electrode with a DEP electric field gradient of selected intensity along with input and a plurality of output fluidic channels. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or groups of particles/cells. The methods are particularly suited for selecting and extracting the best sperm and embryo candidates based on fitness for use with existing artificial reproduction procedures and excluding defective or non-viable gametes. |
| FILED | Thursday, June 18, 2015 |
| APPL NO | 14/743542 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/027 (20130101) B01L 2200/0652 (20130101) B01L 2300/0864 (20130101) B01L 2400/0424 (20130101) B01L 2400/0454 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) Original (OR) Class B03C 5/026 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/00 (20130101) G01N 15/1031 (20130101) G01N 27/447 (20130101) G01N 2015/0003 (20130101) G01N 2015/0065 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106397 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Eun Sok Kim (Rancho Palos Verdes, California); Youngki Choe (Los Angeles, California); Jonathan W. Kim (Rancho Palos Verdes, California); K. Kirk Shung (Monterey Park, California) |
| ABSTRACT | In some aspects of the disclosure, an apparatus includes an XYZ control stage and an acoustic transducer coupled with the XYZ control stage. The acoustic transducer includes a multi-foci Fresnel lens having multiple focal spots. |
| FILED | Tuesday, April 23, 2013 |
| APPL NO | 13/868965 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) Original (OR) Class B81B 3/0027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 29/221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106479 | Stoltz et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Brian M. Stoltz (San Marino, California); Alexander N. Marziale (Basel, Switzerland); Robert A. Craig (Stanford, California); Douglas Duquette (Los Angeles, California); Kelly E. Kim (Pasadena, California); Marc Liniger (Baden, Switzerland); Yoshitaka Numajiri (Kamakura, Japan) |
| ABSTRACT | This invention provides efficient and scalable enantioselective methods that yield 2-alkyl-2-allylcycloalkyanone compounds with quaternary stereogenic centers. Methods include the method for the preparation of a compound of formula (I): comprising treating a compound of formula (II) or (III): with a palladium (II) catalyst under alkylation conditions. |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/081157 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/04 (20130101) B01J 2231/44 (20130101) B01J 2531/004 (20130101) Acyclic or Carbocyclic Compounds C07C 45/65 (20130101) Original (OR) Class C07C 45/65 (20130101) C07C 45/65 (20130101) C07C 49/647 (20130101) C07C 49/683 (20130101) C07C 2601/14 (20170501) C07C 2601/18 (20170501) C07C 2601/20 (20170501) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 211/94 (20130101) C07D 223/10 (20130101) C07D 317/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106502 | Hu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); The Broad Institute, inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Longqin Hu (Belle Mead, New Jersey); Sadagopan Magesh (Highland Park, New Jersey); Lin Chen (Piscataway, New Jersey); Timothy Lewis (Marlborough, Massachusetts); Ben Munoz (Netwonville, Massachusetts); Lili Wang (Chestnut Hill, Massachusetts) |
| ABSTRACT | A method of identifying compounds as direct inhibitors of Keap1-Nrf2 interaction through high-throughput screening and lead development. The direct inhibitors of Keap1-Nrf2 interaction are more specific and free of various undesirable effects than existing indirect inhibitors, and are potential drug candidates of chemopreventive and therapeutic agents for treatment of various diseases or conditions involving oxidative stress and/or inflammation, including but not limited to cancers, diabetes, Alzheimer's, and Parkinson's. Novel compounds are identified and methods of preventing or treating diseases or conditions related to Keap1-Nrf2 interaction activity by use of the novel compounds identified or compositions containing such compounds are also disclosed. |
| FILED | Thursday, September 28, 2017 |
| APPL NO | 15/718987 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/472 (20130101) A61K 31/4725 (20130101) Heterocyclic Compounds C07D 207/452 (20130101) C07D 209/48 (20130101) Original (OR) Class C07D 217/16 (20130101) C07D 335/06 (20130101) C07D 401/06 (20130101) C07D 401/14 (20130101) C07D 405/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106507 | Shönbrunn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Insitute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Ernst Shönbrunn (Tampa, Florida); Nicholas J. Lawrence (Tampa, Florida); Harshani R. Lawrence (Tampa, Florida) |
| ABSTRACT | Disclosed herein are compounds that are inhibitors of BRD4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BRD4 are also disclosed. In certain aspects, disclosed are compounds of Formula I-IV. |
| FILED | Monday, August 03, 2015 |
| APPL NO | 15/501613 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 239/48 (20130101) Original (OR) Class C07D 239/70 (20130101) C07D 239/95 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 491/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106536 | Resnick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Knopp Biosciences LLC (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Knopp Biosciences LLC (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Lynn Resnick (Pittsburgh, Pennsylvania); George T. Topalov (Pittsburgh, Pennsylvania); Charles A. Flentge (Mars, Pennsylvania); James S. Hale (Pittsburgh, Pennsylvania); David A. Mareska (McMurray, Pennsylvania) |
| ABSTRACT | Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 15/591884 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106549 | Pajouhesh et al. |
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| FUNDED BY |
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| APPLICANT(S) | SITEONE THERAPEUTICS, INC. (Redwood City, California); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | SITEONE THERAPEUTICS, INC. (Bozeman, Montana); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Hassan Pajouhesh (Redwood City, California); George Miljanich (Redwood City, California); John Mulcahy (Redwood City, California); Justin Du Bois (Menlo Park, California); Matthew Axtman (Cary, North Carolina); James Walker (Menlo Park, California); Jeffrey E. Merit (San Diego, California) |
| ABSTRACT | Provided herein are compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function, for example conditions associated with pain. The compounds are 10′,11′-modified saxitoxins. The compounds are optionally additionally modified at carbon 13. In certain embodiments, the 10′,11′-modified saxitoxins are of Formula I: where R1, R2 and R3 are as described herein. Also provided herein are methods of treating pain in a mammal comprising administering an effective treatment amount of a 10′,11′ modified saxitoxin or composition to a mammal. In an embodiment, the mammal is a human. |
| FILED | Thursday, April 09, 2015 |
| APPL NO | 15/302964 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106555 | Koehler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Angela N. Koehler (Belmont, Massachusetts); Eric Stefan (Boston, Massachusetts); Francisco Caballero (Brookline, Massachusetts); Dylan Vijith Neel (Providence, Rhode Island); Nicholas B. Struntz (Cambridge, Massachusetts); Helen L. Evans (Cambridge, Massachusetts); Andrew Chen (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compounds of Formula (I′), Formula (I), Formula (II), Formula (II-A), Formula (III), and Formula (IV). The compounds described herein are MAX binders and/or modulators of Myc, Mad, or Mxi1 (e.g., inhibitors of Myc, Mad, or Mxi1), and may be useful in treating a subject with a disease associated with Myc, such as proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions and kits including the compounds described herein, as well as methods of using and uses of the compounds, compositions, and kits. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 15/435003 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 233/28 (20130101) C07D 491/107 (20130101) C07D 498/04 (20130101) Original (OR) Class C07D 498/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106572 | Rivera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jose M Rivera (San Juan, Puerto Rico); Luis M Negron (Corozal, Puerto Rico) |
| ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
| INVENTOR(S) | Jose M Rivera (San Juan, Puerto Rico); Luis M Negron (Corozal, Puerto Rico) |
| ABSTRACT | The invention is directed to small molecules that self-assemble hierarchically to form NPs termed SHS (due to their architectural features). These SHS are composed by precise supramolecules known as Supramolecular G-Quadruplexes (SGQs) which are formed when amphiphilic guanosine (G) derivatives that self-assemble in presence of salt by non-covalent interactions. The resulting SGQs are made of amphiphilic guanosine (G) subunits (with precisely eight subunits at neutral pH (pH>5.7) or sixteen subunits at acidic pH (pH<5.7)). The SGQs are responsive entities that further self-assemble upon an external stimulus, such as an increase in temperature or a change in pH, leading to the formation of the aforementioned SHS. |
| FILED | Friday, July 03, 2015 |
| APPL NO | 14/791360 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48092 (20130101) A61K 47/48961 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106583 | Marozsan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Andre Marozsan (Milford, Connecticut); Albert Cupo (Stamford, Connecticut); John Moore (New York, New York) |
| ABSTRACT | Expression vectors and mammalian cell lines containing them are described that enable the recombinant production of HIV-1 envelope proteins, including SOSIP modified gp140 trimers capable of inducing broadly neutralizing antibodies. |
| FILED | Monday, March 09, 2015 |
| APPL NO | 15/124306 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106584 | Chuong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Amy Chuong (Ashburn, Virginia); Nathan Klapoetke (Ashburn, Virginia); Brian Yichiun Chow (Cherry Hill, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Xue Han (Chestnut Hill, Massachusetts) |
| ABSTRACT | Compositions and methods for altering cell activity and function by expressing a light-activated ion pump polypeptide in a cell and contacting the cell with light that activates the expressed light-activated ion pump polypeptide. In some aspects of the invention, a light-activated ion pump polypeptide is a modified haloarcula halorhodopsin polypeptide, for example, a modified Halo 57 polypeptide. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/282251 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) A61K 41/0057 (20130101) Peptides C07K 14/215 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) C12N 5/0619 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5032 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 530/825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106585 | Herzog et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadephia, Pennsylvania); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Roland W. Herzog (Gainesville, Florida); Henry Daniell (Media, Pennsylvania) |
| ABSTRACT | Protein replacement therapy for patients with hemophilia or other inherited protein deficiencies is often complicated by pathogenic antibody responses, including antibodies that neutralize the therapeutic protein or that predispose to potentially life-threatening anaphylactic reactions by formation of IgE. Using murine and canine hemophilia as a model, we have developed a prophylactic protocol against such responses that is non-invasive and does not include immune suppression or genetic manipulation of the patient's cells. Oral delivery of a coagulation factor expressed in chloroplasts, bioencapsulated in plant cells, effectively blocked formation of inhibitory antibodies in protein replacement therapy. Inhibitor titers were mostly undetectable and up to 100-fold lower in treated subjects when compared to controls. Moreover, this treatment eliminated fatal anaphylactic reactions that occurred after four to six exposures to intravenous coagulation factor protein. Finally, the method can effectively be used to reverse or reduce undesirable pre-existing inhibitor titers. |
| FILED | Monday, May 16, 2016 |
| APPL NO | 15/037045 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 36/00 (20130101) A61K 38/36 (20130101) A61K 38/37 (20130101) A61K 38/45 (20130101) A61K 38/47 (20130101) Peptides C07K 14/28 (20130101) Original (OR) Class C07K 14/755 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8214 (20130101) C12N 15/8257 (20130101) Enzymes C12Y 204/00 (20130101) C12Y 302/0102 (20130101) C12Y 302/01022 (20130101) Technologies for Adaptation to Climate Change Y02A 50/471 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106590 | Walensky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institutes, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Loren D. Walensky (Newton Centre, Massachusetts); Michelle L. Stewart (Brookline, Massachusetts); Lauren Barclay (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are polypeptides containing stabilized BH4 domains of BCL-2 family proteins that are capable of binding and/or inactivating and/or modulating BAX protein, and/or its close homologs BAK and BOK, and/or other physiological BH4 targets. Also provided are compositions containing these polypeptides and methods of treating cytotoxic diseases that include administering to a subject one of the polypeptides. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/777391 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 38/00 (20130101) A61K 38/1761 (20130101) A61K 45/06 (20130101) A61K 49/0008 (20130101) Peptides C07K 14/4747 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 2333/47 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106597 | Popel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Aleksander S. Popel (Lutherville, Maryland); Elena V. Rosca (Baltimore, Maryland); Jacob E. Koskimaki (Baltimore, Maryland); Corban G. Rivera (Baltimore, Maryland); Niranjan B. Pandey (White Marsh, Maryland); Amir P. Tamiz (Silver Spring, Maryland) |
| ABSTRACT | Mimetic peptides having anti-angiogenic and anti-tumorigenic properties and methods of their use for treating cancer, ocular diseases, such as age-related macular degeneration, and other-angiogenesis-dependent diseases are disclosed. More particularly, active non-cysteine analogs (mimetics), which exhibit anti-angiogenic activity in endothelial cell proliferation, migration, adhesion, and tube formation assays, anti-migratory activity in human breast cancer cells in vitro, anti-angiogenic and anti-tumorigenic activity in vivo in breast cancer xenograft models, and age-related macular degeneration models are disclosed. The presently disclosed mimetic peptides also exhibit anti-lymphangiogenic and directly anti-tumorigenic properties. |
| FILED | Friday, December 30, 2016 |
| APPL NO | 15/395648 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106611 | Wucherpfennig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kai W. Wucherpfennig (Brookline, Massachusetts); Glenn Dranoff (Sudbury, Massachusetts); F. Stephen Hodi (Framingham, Massachusetts); Bettina Franz (Orem, Utah); Kenneth F. May, Jr. (Bozeman, Montana); Christopher Harvey (Boston, Massachusetts) |
| ABSTRACT | The present disclosure provides, in part, compositions comprising peptides immunospecifically binds to MHC class I polypeptide-related sequence A (MICA). |
| FILED | Friday, December 05, 2014 |
| APPL NO | 15/100060 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/2833 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106619 | Croft et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael Croft (San Diego, California); Shahram Salek-Ardakani (San Diego, California); Magdalini Moutaftsi (Del Mar, California); Alessandro Sette (La Jolla, California); Carl F. Ware (Solana Beach, California) |
| ASSIGNEE(S) | La Jolla Institute for Allergy and Immunology (La Jolla, California) |
| INVENTOR(S) | Michael Croft (San Diego, California); Shahram Salek-Ardakani (San Diego, California); Magdalini Moutaftsi (Del Mar, California); Alessandro Sette (La Jolla, California); Carl F. Ware (Solana Beach, California) |
| ABSTRACT | The invention relates to compositions and methods that employ OX40 (CD134), a TNFR superfamily protein, agonists. The invention includes among other things administering an OX40 agonist alone or in combination with a viral antigen, or live or attenuated virus, to treat a viral infection, or for vaccination or immunization. |
| FILED | Thursday, October 04, 2007 |
| APPL NO | 11/867621 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/505 (20130101) A61K 2039/5254 (20130101) A61K 2039/55516 (20130101) Peptides C07K 16/2878 (20130101) Original (OR) Class C07K 2317/75 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106620 | Childs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); Janssen Biotech, Inc. (Spring House, Pennsylvania) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Janssen Biotech, Inc. (Spring House, Pennsylvania) |
| INVENTOR(S) | Richard W. Childs (Rockville, Maryland); Maria Berg (Bethesda, Maryland); Luis Espinoza Calderon (Bethesda, Maryland); Kate Sasser (Spring House, Pennsylvania); Ricardo Attar (Spring House, Pennsylvania) |
| ABSTRACT | Provided herein are methods of inhibiting growth or proliferation of cells expressing CD38 by contacting the CD38-expressing cells with 1) NK cells bound to an anti-CD38 F(ab′)2 fragment and 2) an anti-CD38 antibody, in either order or simultaneously. Also provided herein are methods of treating or inhibiting a hyperproliferative disorder or an autoimmune disorder in a subject by administering to the subject 1) NK cells bound to an anti-CD38 F(ab′)2 fragment and 2) an anti-CD38 antibody, in either order or simultaneously. |
| FILED | Monday, June 15, 2015 |
| APPL NO | 15/319344 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) A61P 37/00 (20180101) Peptides C07K 16/2896 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/732 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106647 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Jian Yang (State College, Pennsylvania); Jinshan Guo (State College, Pennsylvania) |
| ABSTRACT | In one aspect, compositions are described herein. In some embodiments, a composition described herein comprises the reaction product of (i) citric acid, a citrate, or an ester of citric acid with (ii) a polyol, and (iii) a monomer comprising one or more alkyne moieties and/or azide moieties. The reaction product, in some instances, comprises a polymer. Further, in some cases, a composition described herein comprises a plurality of polymers. In some embodiments, the polymers are selected to be reactive with one another through a click chemistry reaction scheme to form a polymer network. In another aspect, medical implants and medical devices are described herein, the implants and devices comprising a polymer or polymer network described herein. |
| FILED | Thursday, September 04, 2014 |
| APPL NO | 14/916140 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/56 (20130101) A61L 2420/04 (20130101) A61L 2430/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/68 (20130101) C08G 18/73 (20130101) C08G 18/4615 (20130101) C08G 63/12 (20130101) C08G 63/52 (20130101) Original (OR) Class C08G 63/6852 (20130101) C08G 63/6858 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106650 | Lam et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kit S. Lam (Davis, California); Yuanpei Li (Davis, California); Juntao Luo (Jamesville, New York); Kai Xiao (Sacramento, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kit S. Lam (Davis, California); Yuanpei Li (Davis, California); Juntao Luo (Jamesville, New York); Kai Xiao (Sacramento, California) |
| ABSTRACT | The present invention provides amphiphilic telodendrimers that aggregate to form nanocarriers characterized by a hydrophobic core and a hydrophilic exterior. The nanocarrier core may include amphiphilic functionality such as cholic acid or cholic acid derivatives, and the exterior may include branched or linear poly(ethylene glycol) segments. Nanocarrier cargo such as hydrophobic drugs and other materials may be sequester in the core via non-covalent means or may be covalently bound to the telodendrimer building blocks. Telodendrimer structure may be tailored to alter loading properties, interactions with materials such as biological membranes, and other characteristics. |
| FILED | Monday, May 14, 2012 |
| APPL NO | 14/117570 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 9/1271 (20130101) A61K 31/337 (20130101) A61K 45/06 (20130101) A61K 47/28 (20130101) A61K 47/60 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/329 (20130101) C08G 65/3348 (20130101) Original (OR) Class C08G 83/004 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10106690 — Surface-independent, surface-modifying, multifunctional coatings and applications thereof
| US 10106690 | Messersmith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Haeshin Lee (Chicago, Illinois) |
| ABSTRACT | The present invention provides a surface-independent surface-modifying multifunctional biocoating and methods of application thereof. The method comprises contacting at least a portion of a substrate with an alkaline solution comprising a surface-modifying agent (SMA) such as dopamine so as to modify the substrate surface to include at least one reactive moiety. In another version of the invention, a secondary reactive moiety is applied to the SMA-treated substrate to yield a surface-modified substrate having a specific functionality. |
| FILED | Thursday, June 09, 2016 |
| APPL NO | 15/178255 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2420/00 (20130101) A61L 2420/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1662 (20130101) Original (OR) Class C09D 5/1681 (20130101) C09D 179/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106771 | Slukvin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Igor Slukvin (Verona, Wisconsin); Irina Elcheva (Madison, Wisconsin) |
| ABSTRACT | Described herein are methods and related compositions for inducing differentiation of human pluripotent stem cells (hPSCs) into hemogenic endothelium with pan-myeloid potential or restricted potential, by forced expression in the hPSCs of a combination of transcription factors as described herein. |
| FILED | Wednesday, August 23, 2017 |
| APPL NO | 15/684647 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) Original (OR) Class C12N 5/0608 (20130101) C12N 5/0647 (20130101) C12N 15/00 (20130101) C12N 15/11 (20130101) C12N 15/66 (20130101) C12N 2501/60 (20130101) C12N 2501/998 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2510/00 (20130101) C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106772 | Thomson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | James A. Thomson (Madison, Wisconsin); Junying Yu (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method. |
| FILED | Monday, March 11, 2013 |
| APPL NO | 13/793594 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0607 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/60 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2502/99 (20130101) C12N 2510/00 (20130101) C12N 2799/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106774 | Stone |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Geoffrey William Stone (Coral Gables, Florida) |
| ABSTRACT | Compositions and methods of activating dendritic cells with LMP1 and LMP1-activated dendritic cell based compositions and methods are effective for dendritic cell therapy and provide an adjuvant function for vaccine administration. LMP1 or LMP1-CD40 chimeric protein may be used to activate and mature dendritic cells. LMP1 and LMP1-activated dendritic cells act as an adjuvant to enhance the cellular immune response. Also disclosed herein are kits for activating dendritic cells and for preparing a vaccine formulation. Administration of the dendritic cells transfected with LMP1 can induce an immune response against cancer or infection. The mature dendritic cells may comprise an antigen and at least one cytokine in addition to LMP1. Use of LMP1 or LMP1-CD40 provides a way to activate and mature dendritic cells that retain functional and migratory abilities without the side effects that result from maturing the dendritic cells using PGE2. |
| FILED | Tuesday, December 23, 2014 |
| APPL NO | 14/580978 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 35/15 (20130101) A61K 38/162 (20130101) A61K 38/162 (20130101) A61K 38/191 (20130101) A61K 38/191 (20130101) A61K 38/204 (20130101) A61K 38/204 (20130101) A61K 38/2006 (20130101) A61K 38/2006 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 39/245 (20130101) A61K 45/06 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) A61K 2039/55511 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/005 (20130101) C07K 14/70578 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0639 (20130101) Original (OR) Class C12N 15/85 (20130101) C12N 2510/00 (20130101) C12N 2710/10043 (20130101) C12N 2710/10071 (20130101) C12N 2710/16244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106776 | Birla |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON (Houston, Texas) |
| INVENTOR(S) | Ravi K. Birla (Sugar Land, Texas) |
| ABSTRACT | In some embodiments, the present disclosure provides a method for fabricating a three-dimensional artificial cardiac patch construct. In some embodiments, such method includes the steps of coating a substrate with an organic polymer; allowing the organic polymer coating to air dry; mounting anchors on the organic polymer coating; and sterilizing the organic polymer coating and the anchors. In further embodiments, the method includes the steps of forming a biodegradable gel-based support scaffold on top of the organic polymer coating and seeding the biodegradable gel-based support scaffold with neonatal cardiac cells. In yet further embodiments, the method comprises culturing the neonatal cardiac cells in vitro to form a real cardiac layer, under culture conditions that are suitable for the cells to self-organize into a monolayer and detach from the substrate to form the three-dimensional cardiac patch. In some embodiments, the present disclosure pertains to a method of treatment of cardiac tissue injury in a subject in need thereof. In some embodiments, the method includes implanting the three-dimensional artificial cardiac patch described above in the injured area of the subject. In another embodiment the present disclosure provides a composition comprising the three-dimensional artificial cardiac patch described above. Additional embodiments of the present disclosure pertain to a medicament including the three-dimensional artificial cardiac patch described above. |
| FILED | Tuesday, May 06, 2014 |
| APPL NO | 14/270766 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 38/18 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/52 (20130101) A61L 27/225 (20130101) A61L 27/3826 (20130101) A61L 2430/20 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 2533/30 (20130101) C12N 2533/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106778 | Tam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Wai Leong Tam (Singapore, Singapore); Robert A. Weinberg (Brookline, Massachusetts) |
| ABSTRACT | Aspects of the invention relate to methods and related compositions for preferentially targeting cancer stem cells. In some embodiments, the methods utilize PKC-α/FRA1 pathway inhibitors to target carcinoma cells. Also provided are methods for identifying a candidate compound for selectively inhibiting growth of cancer stem cell, and methods for obtaining cells that have undergone an epithelial to mesenchymal transition. |
| FILED | Friday, November 08, 2013 |
| APPL NO | 14/441697 |
| ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/403 (20130101) A61K 31/404 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/553 (20130101) A61K 31/704 (20130101) A61K 31/713 (20130101) A61K 31/4045 (20130101) A61K 31/7105 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) C12N 2501/727 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106780 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ankur Singh (Smyrna, Georgia); Shalu Suri (Smyrna, Georgia); Todd Christopher McDevitt (Atlanta, Georgia); Hang Lu (Atlanta, Georgia); Andres Jose Garcia (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ankur Singh (Smyrna, Georgia); Shalu Suri (Smyrna, Georgia); Todd Christopher McDevitt (Atlanta, Georgia); Hang Lu (Atlanta, Georgia); Andres Jose Garcia (Atlanta, Georgia) |
| ABSTRACT | The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces. |
| FILED | Thursday, June 21, 2012 |
| APPL NO | 14/128547 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2506/45 (20130101) C12N 2509/10 (20130101) C12N 2527/00 (20130101) C12N 2539/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106781 | Barouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Dan H. Barouch (Newton, Massachusetts); Herbert Virgin, IV (St. Louis, Missouri); Peter Abbink (Jamaica Plain, Massachusetts) |
| ABSTRACT | The present invention relates to recombinant adenoviruses and vectors thereof. In particular, the adenoviruses are novel simian adenoviruses having a low seroprevalence and high immunogenicity relative to other adenoviruses and vectors thereof. The invention also provides methods for production of the adenoviruses and for the treatment of diseases by administering the adenoviral vector(s) to a subject (e.g., a human). |
| FILED | Friday, November 15, 2013 |
| APPL NO | 14/443299 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/12 (20130101) A61K 2039/5256 (20130101) A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2710/10042 (20130101) C12N 2710/10321 (20130101) C12N 2710/10343 (20130101) C12N 2740/15034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106786 | Camire |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Rodney M. Camire (Sicklerville, New Jersey) |
| ABSTRACT | Factor X/Xa variants and methods of use thereof are disclosed. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/172904 |
| ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/36 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6432 (20130101) Original (OR) Class Enzymes C12Y 304/21006 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106787 | Li |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wei Li (Miami Beach, Florida) |
| ASSIGNEE(S) | Wei Li (Miami, Florida) |
| INVENTOR(S) | Wei Li (Miami Beach, Florida) |
| ABSTRACT | The present invention is directed to methods for systematic identification of cellular ligands, disease-associated ligands, age-related ligands and receptor-specific ligands. Disease-associated ligands are promising targets to develop novel ligand-based therapies. The methods are broadly applicable to any type of cells or diseases in in vitro and in vivo settings. This invention further used the methods to identify Scg3 as a disease-related angiogenic factor for the therapy of diabetic retinopathy, diabetic macular edema, proliferative diabetic retinopathy, vascular age-related macular degeneration, diabetic foot and cancers. |
| FILED | Friday, May 08, 2015 |
| APPL NO | 14/708073 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 14/515 (20130101) C07K 16/22 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class C12N 15/1037 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2535/122 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106790 | Sundstrom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Paula R. Sundstrom (Lebanon, New Hampshire); Samin Kim (Norwich, Vermont); Quoc Bao Nguyen (Ho Chi Minh, Viet Nam) |
| ABSTRACT | Intergenic non-coding RNA molecules that regulate the expression of HWP1 and ALS3 of Candida are provided as are methods of using the non-coding RNA molecules and complementary molecules thereof in modulating HWP1 or ALS3 expression; adherence, yeast-to-hyphal transition, or biofilm development of Candida; and preventing or treating candidiasis. |
| FILED | Friday, September 18, 2015 |
| APPL NO | 15/513312 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Peptides C07K 14/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/67 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/111 (20130101) C12N 2310/113 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/3521 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106792 | Rossi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California); INTEGRATED DNA TECHNOLOGIES, INC. (Coralville, Iowa) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California); INTEGRATED DNA TECHNOLOGIES, INC. (Coralville, Iowa) |
| INVENTOR(S) | John J. Rossi (Alta Loma, California); Mark A. Behlke (Coralville, Iowa); Dongho Kim (Los Angeles, California) |
| ABSTRACT | The invention is directed to compositions and methods for selectively reducing the expression of a gene product from a desired target gene in a cell, as well as for treating diseases caused by the expression of the gene. More particularly, the invention is directed to compositions that contain double stranded RNA (“dsRNA”), and methods for preparing them, that are capable of reducing the expression of target genes in eukaryotic cells. The dsRNA has a first oligonucleotide sequence that is between 25 and about 30 nucleotides in length and a second oligonucleotide sequence that anneals to the first sequence under biological conditions. In addition, a region of one of the sequences of the dsRNA having a sequence length of at least 19 nucleotides is sufficiently complementary to a nucleotide sequence of the RNA produced from the target gene to trigger the destruction of the target RNA by the RNAi machinery. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/375730 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/33 (20130101) C12N 2310/50 (20130101) C12N 2310/51 (20130101) C12N 2320/30 (20130101) C12N 2320/50 (20130101) C12N 2320/51 (20130101) C12N 2330/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106803 | Lindquist et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Susan L. Lindquist (Cambridge, Massachusetts); Aaron D. Gitler (Foster City, California) |
| ABSTRACT | Disclosed are yeast cells expressing TAR DNA-binding protein 43 (TDP-43) and methods of screening yeast cells to identify compounds that prevent or suppress TDP-43-induced toxicity, compounds that inhibit the formation or maintenance of cytoplasmic inclusions of TDP-43, genetic suppressors or enhancers of TDP-43-induced toxicity, and genetic suppressors or enhancers of the formation or maintenance of cytoplasmic inclusions of TDP-43. Compounds identified by such screens can be used to treat or prevent TDP-43 proteinopathies such as frontotemporal lobar degeneration or amyotrophic lateral sclerosis. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 15/650094 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) Original (OR) Class C12N 15/1079 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) G01N 33/6896 (20130101) G01N 2500/10 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106816 | Arts |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Eric J. Arts (Cleveland, Ohio) |
| ABSTRACT | A synthetic lentiviral vector construct comprises a genomic RNA packaging enhancer (GRPE) element and lentiviral nucleic acid sequences sufficient for reverse transcription and packaging in a host cell. |
| FILED | Monday, December 16, 2013 |
| APPL NO | 14/652335 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2740/15042 (20130101) C12N 2740/15052 (20130101) C12N 2740/16043 (20130101) C12N 2740/16222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106817 | Weinberger |
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| FUNDED BY |
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| APPLICANT(S) | The J. David Gladstone Institutes (San Francisco, California) |
| ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
| INVENTOR(S) | Leor S. Weinberger (San Francisco, California) |
| ABSTRACT | A recombinant expression vector comprising a nucleotide sequence encoding a herpesvirus transactivator, where the nucleotide sequence is operably linked to a herpesvirus control element is provided as are cell lines genetically modified to express a herpesvirus transactivator under the control of a herpesvirus control element. Also provided are methods of identifying agents that disrupt feedback regulation of a herpesvirus transcriptional control element by a herpesvirus transactivator. |
| FILED | Thursday, February 13, 2014 |
| APPL NO | 14/767541 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/16122 (20130101) C12N 2710/16143 (20130101) C12N 2740/15043 (20130101) C12N 2830/00 (20130101) C12N 2830/48 (20130101) C12N 2830/60 (20130101) C12N 2840/203 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106818 | Verdin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE J. DAVID GLADSTONE INSTITUTES (San Francisco, California) |
| ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
| INVENTOR(S) | Eric M. Verdin (Mill Valley, California); Vincenzo Calvanese (West Hollywood, California) |
| ABSTRACT | The present disclosure provides for recombinant nucleic acids, and cells and virions comprising the recombinant nucleic acids, that can be used to identify, isolate, and/or purify cells latently infected with immunodeficiency virus. A subject recombinant nucleic acid includes (a) a first nucleotide sequence encoding a first reporter polypeptide that produces a first detectable signal, where the first nucleotide sequence is operably linked to an immunodeficiency virus promoter and is translated as an early gene; and (b) a second nucleotide sequence encoding a second reporter polypeptide that produces a second detectable signal that is distinguishable from the first detectable signal, where the second nucleotide sequence is operably linked to a non-immunodeficiency virus promoter. In some aspects, the first and second nucleotide sequences are both positioned between a shared 5′ long terminal repeat (LTR) and a shared 3′ LTR. Also provided are related methods. |
| FILED | Thursday, August 14, 2014 |
| APPL NO | 14/910665 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2740/16011 (20130101) C12N 2740/16043 (20130101) C12N 2830/60 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) C12Q 1/6897 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106833 | Kahne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel Evan Kahne (Brookline, Massachusetts); Suzanne Walker Kahne (Brookline, Massachusetts); Christian M. Gampe (Brighton, Massachusetts); Hirokazu Tsukamoto (Sendai, Japan) |
| ABSTRACT | The present invention provides moenomycin-based probe compounds of Formula (I) for use in screening inhibitors of bacterial glycosyltransferases. The present invention also provides bacterial glycosyltransferase screening assays using compounds of Formula (I). |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 14/390857 |
| ART UNIT | 1673 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 11/04 (20130101) C07H 13/12 (20130101) C07H 15/26 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91091 (20130101) G01N 2500/04 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106834 | Georgopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Tufts Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Tufts Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Katia Georgopoulos (Lexington, Massachusetts); Richard A. Etten (Laguna Beach, California); Ila Joshi (Malden, Massachusetts) |
| ABSTRACT | Methods for the diagnosis and treatment of B cell Acute Lymphoblastic Leukemia (B-ALL), based in part on the detection and/or inhibition of Focal Adhesion Kinase (FAK), e.g., phosphorylated FAK (pFAK). |
| FILED | Thursday, October 09, 2014 |
| APPL NO | 15/028515 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57426 (20130101) G01N 2333/912 (20130101) G01N 2800/52 (20130101) G01N 2800/54 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106848 | Ramsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); Laurent Menard (Raleigh, North Carolina) |
| ABSTRACT | Devices and methods generate an ordered restriction map of genomic DNA extracted from whole cells. The devices have a fluidic microchannel that merges into a reaction nanochannel that merges into a detection nanochannel at an interface where the nanochannel diameter decreases in size by between 50% to 99%. Intact molecules of DNA are transported to the reaction nanochannel and then fragmented in the reaction nanochannel using restriction endonuclease enzymes. The reaction nanochannel is sized and configured so that the fragments stay in an original order until they are injected into the detection nanochannel. Signal at one or more locations along the detection nanochannel is detected to map fragments in the order they occur along a long DNA molecule. |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 15/446630 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/683 (20130101) C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106853 | Zhou |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Pengbo Zhou (Princeton Junction, New Jersey) |
| ABSTRACT | The current disclosure describes materials and methods for identifying subjects that would benefit from treatment with a DNA topoisomerase 1 inhibitor, based on the levels of cullin 4B gene, RNA and protein levels in the subject. The disclosure identifies CUL4B as a predictive biomarker for cancer diagnosis and the subsequent treatment with directed therapeutic agents. The current disclosure also identifies novel therapeutic agents that modulate the level of CUL4B expression, and sensitize a subject to treatment with a second therapeutic agent. |
| FILED | Friday, May 03, 2013 |
| APPL NO | 14/398870 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 31/7105 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 33/57484 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106855 | Spivak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jerry L Spivak (Baltimore, Maryland); Michael Ochs (Oreland, Pennsylvania); Michael Considine (Bel Air, Maryland); Donna Rowley (Beltsville, Maryland); Alison R Moliterno (Baltimore, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides a genetic assay to determine the prognosis in Polycythemia Vera (PV) patients with an indolent form of PV. This assay involves measuring certain messenger RNAs (mRNAs) in blood cells, such as white blood cells. In some embodiments, the cells are CD34+ cells. These mRNA levels are inserted into an algorithm that yields a predictive score of the risk of PV in the patient transforming from an indolent form to an aggressive form. |
| FILED | Friday, November 08, 2013 |
| APPL NO | 14/441721 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/80 (20130101) G01N 2800/52 (20130101) G01N 2800/226 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107613 | Jiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Shuliang Jiao (Los Angeles, California); Hao Zhang (Evanston, Illinois) |
| ABSTRACT | A system and method for providing an optical coherence photoacoustic (OC-PAM) microscopy. An OC-PAM microscope includes a light source that outputs light, a scanner, a detector, a transducer, and an image processing module. The scanner receives the light and scans the light across a sample. The detector receives reflected light from the sample in response to the scanned light. The transducer detects photoacoustic waves induced in the sample by the scanned light. The image processing module receives output from the detector and the transducer and generates a photoacoustic microscopy (PAM) image and an optical coherence tomography (OCT) image based on the received output from the detector and the transducer. The PAM and OCT image data may be fused to form a single, OC-PAM image. Additionally, a series of PAM images and OCT images, respectively, may be combined to generate three-dimensional PAM and OCT images, respectively. |
| FILED | Tuesday, August 30, 2016 |
| APPL NO | 15/251610 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0203 (20130101) Original (OR) Class G01B 9/02091 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/0681 (20130101) G01N 29/2418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107616 | Zhou |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lehigh University (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | LEHIGH UNIVERSITY (, None) |
| INVENTOR(S) | Chao Zhou (Bethlehem, Pennsylvania) |
| ABSTRACT | A space-division multiplexing optical coherence tomography apparatus and system is provided. In one embodiment, the system includes a light source, a reference arm, and a sample arm. The sample arm splits the sampling light into a plurality of sampling beams which may be scanned simultaneously onto a surface of a sample. An optical delay may be introduced into the sampling beams before scanning. A plurality of reflected light signals returned from the sample is collected. In one arrangement, the signals may be combined to produce a single reflected light signal. The reflected light signal(s) and a reference signal are combined to produce an interference signal comprising data representative of digitized images captured of the actual object. In one embodiment, a single sample arm may be used for scanning and collecting image data. A related method is also provided. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/191006 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02004 (20130101) G01B 9/02019 (20130101) G01B 9/02028 (20130101) G01B 9/02041 (20130101) G01B 9/02091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107807 | Lakowicz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph R. Lakowicz (Ellicott City, Maryland); Ramachandram Badugu (Ellicott City, Maryland) |
| ASSIGNEE(S) | The University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Joseph R. Lakowicz (Ellicott City, Maryland); Ramachandram Badugu (Ellicott City, Maryland) |
| ABSTRACT | Techniques for enhanced fluorescence include a functionalized substrate for a target optical frequency comprising a one dimensional photonic crystal that is functionalized with a bioactive target molecule that has an affinity for a particular analytic. The one dimensional photonic crystal includes a plurality of dielectric layers including a plurality of high index of refraction layers alternating with a plurality of low index of refraction layers. The thickness of each layer is within a factor of four of a wavelength of the optical frequency in the layer. For emissions from a fluorophore bound to the target molecule and excited by incident light, there is an emission intensity maximum centered at an angle independent of the direction of the incident light. |
| FILED | Thursday, May 21, 2015 |
| APPL NO | 14/718464 |
| ART UNIT | 1677 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6445 (20130101) G01N 21/7703 (20130101) G01N 33/58 (20130101) G01N 33/551 (20130101) G01N 33/552 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 2021/7786 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) G02B 5/008 (20130101) G02B 6/1225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107835 | Murray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (Baton Rouge, Louisiana) |
| INVENTOR(S) | Kermit King Murray (Baton Rouge, Louisiana); Suman Ghorai (Baton Rouge, Louisiana); Chinthaka Aravinda Seneviratne (Baton Rouge, Louisiana) |
| ABSTRACT | Disclosed are various embodiments for transferring molecules from a surface for mass spectrometry and other sample analysis methods, and the like. A laser is focused onto a tip of an atomic force microscope to remove and capture a quantity of molecules from the surface, so they can be transferred to a mass spectrometer or another instrument for analysis. |
| FILED | Thursday, January 07, 2016 |
| APPL NO | 15/541731 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/16 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/02 (20130101) Original (OR) Class G01Q 60/40 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/40 (20130101) H01J 49/0418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108776 | Miller, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Thomas F. Miller, III (South Pasadena, California); William M. Clemons, Jr. (Pasadena, California); Stephen Marshall (Pasadena, California); Axel Mueller (Pasadena, California); Michiel Niesen (Monrovia, California); Bin Zhang (Houston, Texas) |
| ABSTRACT | Methods and systems are described to provide computerized trajectory-based methods to represent translocon-associated protein trajectories, provide proteins or protein sequences with desired translocon-associated biogenesis features, screening proteins or protein sequences to provide proteins or protein sequences with desired translocon-associated biogenesis features, screening translocon-associated biogenesis feature determinants to provide proteins or protein sequences with desired translocon-associated biogenesis features, identifying translocon-associated biogenesis feature determinants of a given protein sequence, computer-based protein sequence identification methods, computer-based methods for identifying correlations in a set of protein sequences, computer-based methods for identifying correlations between experimental data and computer-generated data in a protein sequence, and computer-based methods for determining which modifications of a protein sequence do not substantially affect a translocon-associated biogenesis feature of the protein sequence. |
| FILED | Tuesday, June 10, 2014 |
| APPL NO | 14/301069 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electric Digital Data Processing G06F 19/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109413 | Sullivan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles R. Sullivan (West Lebanon, New Hampshire) |
| ABSTRACT | A multilayer conductor includes at least one separation dielectric layer and a plurality of conductor layers stacked in an alternating manner. Each of the plurality of conductor layers includes a first conductor sublayer and a second conductor sublayer separated from the first conductor sublayer by a sublayer dielectric layer. The second conductor sublayer at least partially overlaps with the first conductor sublayer in each of the plurality of conductor layers. The multilayer conductor is included, for example, in a device including a magnetic core adjacent to at least part of the multilayer conductor. |
| FILED | Friday, January 31, 2014 |
| APPL NO | 14/765306 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 17/0013 (20130101) H01F 27/16 (20130101) H01F 27/24 (20130101) H01F 27/34 (20130101) Original (OR) Class H01F 27/2804 (20130101) H01F 2017/0026 (20130101) H01F 2027/2809 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/16 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109976 | Wise et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Frank W. Wise (Ithaca, New York); Erin Stranford Lamb (Ithaca, New York); Logan Wright (Ithaca, New York) |
| ABSTRACT | Methods, systems, and devices are disclosed for divided-pulse lasers. In one aspect, a pulsed laser is provided to include a laser cavity including an optical amplifier and a plurality of optical dividing elements and configured to direct a laser pulse of linearly polarized light into the plurality of optical dividing elements to divide the light of the laser pulse into a sequence of divided pulses each having a pulse energy being a portion of the energy of the laser pulse before entry of the optical dividing elements, to subsequently direct the divided pulses into the optical amplifier to produce amplified divided pulses. The laser cavity is configured to direct the amplified divided pulses back into the plurality of optical dividing elements for a second time in an opposite direction to recombine the amplified divided pulses into a single laser pulse with greater pulse energy as an output pulse of the laser cavity. |
| FILED | Wednesday, January 21, 2015 |
| APPL NO | 15/113349 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/08 (20130101) H01S 3/081 (20130101) H01S 3/0826 (20130101) H01S 3/1118 (20130101) H01S 3/1618 (20130101) H01S 3/2333 (20130101) H01S 3/06712 (20130101) Original (OR) Class H01S 3/06791 (20130101) H01S 3/08054 (20130101) H01S 3/10046 (20130101) H01S 2301/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10105149 | Haider et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska); TRAK SURGICAL, INC. (San Jose, California) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska); Trak Surgical, Inc. (San Jose, California) |
| INVENTOR(S) | Hani Haider (Carter Lake, Iowa); Ibrahim Al-Shawi (Amman, Jordan); Osvaldo Andres Barrera (Omaha, Nebraska); David Scott Saunders (Redwood City, California) |
| ABSTRACT | A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer aided surgery and the devices used during such procedures. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled using the OTT device. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure including the rate of and type of data processed depending upon a CAS mode. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/776755 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/16 (20130101) A61B 17/17 (20130101) Original (OR) Class A61B 17/142 (20161101) A61B 34/20 (20160201) A61B 2017/00734 (20130101) A61B 2034/105 (20160201) A61B 2034/2055 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105434 | Simmons et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Monika Simmons (Germantown, Maryland); Joseph Robert Putnak (Monongahela, Pennsylvania) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia); The United States of America as represented by the Sec. of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Monika Simmons (Germantown, Maryland); Joseph Robert Putnak (Monongahela, Pennsylvania) |
| ABSTRACT | The invention relates to a method for preventing, ameliorating or treating disease caused by dengue virus in a subject in need thereof comprising administering to the subject a dengue vaccine formulation in combination with a NS3 helicase polypeptide and/or fragment(s) thereof, wherein said method comprises stimulating humoral as well as cell-mediated immunity to the dengue virus in the subject. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/224881 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/5252 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/14 (20130101) C12N 2770/24121 (20130101) C12N 2770/24134 (20130101) C12N 2770/24171 (20130101) Enzymes C12Y 306/04013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105446 | Gmeiner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina) |
| INVENTOR(S) | William H. Gmeiner (Yadkinville, North Carolina) |
| ABSTRACT | Provided herein are aptamers and pharmaceutical compositions comprising the same. In some embodiments, the aptamer selectively binds a protein of interest such as an extracellular receptor protein of interest (e.g., a cancer cell extracellular receptor protein, which may be differentially expressed in some embodiments). In some embodiments, the aptamer is directly linked by covalent bonding (e.g., via a geminal diamine linkage) to from 2 to 10 toxin compounds. Also provided herein is a method of selecting an aptamer that specifically binds to a protein expressed by a cell of interest, wherein in some embodiments the aptamer comprises at least one binding site for one or more active compounds. In some embodiments, primer regions flanking the variable region of the aptamers in the pool contains from 1 to 10 mismatches with respect to said forward or reverse primer. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/285916 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/704 (20130101) A61K 31/7048 (20130101) A61K 47/48092 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/351 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105448 | Guerry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Patricia Guerry (Silver Spring, Maryland); Mario Artur Monteiro (Guelph, Canada); Stephen Savarino (Kensington, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Patricia Guerry (Silver Spring, Maryland); Mario Artur Monteiro (Guelph, Canada); Stephen Savarino (Kensington, Maryland) |
| ABSTRACT | The inventive subject matter relates to a construct comprising antigens derived from multiple enterobacteria including Campylobacter jejuni capsule polysaccharide polymer, enterotoxigenic Escherichia coli recombinant polypeptide construct and lipopolysaccharide from Shigella spp. The subject invention also relates to a method of inducing an immune response utilizing the inventive composition. |
| FILED | Tuesday, May 26, 2015 |
| APPL NO | 14/721656 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/105 (20130101) A61K 39/0258 (20130101) A61K 39/0283 (20130101) A61K 47/646 (20170801) Original (OR) Class A61K 47/6415 (20170801) A61K 2039/70 (20130101) A61K 2039/6037 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/245 (20130101) C07K 16/44 (20130101) C07K 16/1232 (20130101) C07K 16/1267 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2319/35 (20130101) Technologies for Adaptation to Climate Change Y02A 50/47 (20180101) Y02A 50/474 (20180101) Y02A 50/476 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105557 | Yurechko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army Edgewood Chemical and Biological Command (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Steven A Yurechko (Abingdon, Maryland); Douglas E. Wilke (Joppa, Maryland) |
| ABSTRACT | The present invention provides an improved filter connection system for a gas mask, comprising: a filter, a mounting means that attaches the filter to the gas mask, and a retainer means to hold the filter within the mounting means. The mounting means includes a protruding means; a valving assembly in communication with the protruding means, wherein the valving assembly enables air to flow from the fitter to the mask when the retainer means retains the protruding means, and disables air flow from the filter to the mask when the protruding means disengages from the retainer means; and a sealing means located within or adjacent to the valving assembly to prevent air from outside of the filter from entering the mounting means. |
| FILED | Wednesday, November 05, 2014 |
| APPL NO | 14/533256 |
| ART UNIT | 3778 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 9/04 (20130101) A62B 18/10 (20130101) Original (OR) Class A62B 23/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105839 | Kornbluh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Roy David Kornbluh (Palo Alto, California); Alexander Steele Kernbaum (Sunnyvale, California); Thomas Low (Belmont, California); Katherine Goss Witherspoon (San Francisco, California); Brian Keith McCoy (Sunnyvale, California); Adam Arnold Edward Ziemba (Menlo Park, California); Paul Michael Birkmeyer (Redwood City, California); Richard M. Mahoney (Los Altos, California) |
| ABSTRACT | A flexible exosuit includes rigid and flexible elements configured to couple forces to a body of a wearer. Further, the flexible exosuit includes flexible linear actuators and clutched compliance elements to apply and/or modulate forces and/or compliances between segments of the body of the wearer. The flexible exosuit further includes electronic controllers, power sources and sensors. The flexible exosuit can be configured to apply forces to the body of the wearer to enable a variety of applications. In some examples, the flexible exosuit can be configured to augment the physical strength or endurance of the wearer. In some examples, the flexible exosuit can be configured to train the wearer to perform certain physical tasks. In some examples, the flexible exosuit can be configured to record physical activities of the wearer. |
| FILED | Friday, September 25, 2015 |
| APPL NO | 14/865047 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class B25J 9/104 (20130101) B25J 9/1615 (20130101) B25J 9/1633 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 28/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/36429 (20130101) G05B 2219/39345 (20130101) G05B 2219/40305 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106238 | Sidki et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leidos, Inc. (Reston, Virginia) |
| ASSIGNEE(S) | Leidos, Inc. (Reston, Virginia) |
| INVENTOR(S) | Nahid Sidki (Great Falls, Virginia); Weicheng Shen (Vienna, Virginia); Suk Lee (Alexandria, Virginia); Andrew Genduso (Fairfax, Virginia) |
| ABSTRACT | A system of modular components can be used with existing sensor suites to fuse data and determine the operating environment (surface contacts/tracks) for an autonomous marine vehicle and feed an autonomy decision engine to improve the vessel arbitration process in deciding which way to turn, how fast to go, obstacle avoidance, and mission monitoring. The system includes the ability to obey the set of navigation rules published by the International Maritime Organization, generally referred to as COLREGS (collision regulations). |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/916839 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 35/00 (20130101) B63B 2035/007 (20130101) Marine Propulsion or Steering B63H 25/04 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0206 (20130101) Traffic Control Systems G08G 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106475 | Harvey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California); Kale Warren Harrison (Ridgecrest, California) |
| ABSTRACT | A method for converting cedarwood oil into high density fuels including, hydrogenating cedarwood oil in the presence of at least one hydrogenation catalyst to generate hydrogenated cedarwood oil, removing the hydrogenation catalyst from the hydrogenated cedarwood oil, purifying the hydrogenated cedarwood oil to produce a first high density fuel, isomerizing the first high density fuel in the presence of at least one acid catalyst to generate a hydrocarbon mixture including adamantanes, and distilling the adamantane mixture to produce a second alkyl-adamantane high density fuel. |
| FILED | Friday, August 18, 2017 |
| APPL NO | 15/680909 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 43/00 (20130101) Acyclic or Carbocyclic Compounds C07C 4/06 (20130101) C07C 5/03 (20130101) Original (OR) Class C07C 5/31 (20130101) C07C 2527/126 (20130101) C07C 2603/74 (20170501) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/08 (20130101) C10L 10/12 (20130101) C10L 2200/0469 (20130101) C10L 2270/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106794 | Niu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Latham, New York) |
| ABSTRACT | The disclosure relates to synthetic oligonucleotides that are unique in that they are RNA molecules that have the capacity to form a hydrogel. Also disclosed are DNA oligonucleotides that encode the RNA oligos so that the oligos can be prepared using in vitro transcription. The disclosure further pertains to pharmaceutical compositions comprising these hydrogels. |
| FILED | Monday, April 03, 2017 |
| APPL NO | 15/477498 |
| ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2210/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106837 | Benner |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven A Benner (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven A Benner (Gainesville, Florida) |
| ABSTRACT | This invention provides a single process that collects any and all target nucleic acids from a sample that can contain any of a number of biological species, including bacteria, viruses, or fungi, where the first step renders the sample nonhazardous and releases nucleic acids from cell structures, compartments, and molecular complexes that may hold them, the second step concentrates the target nucleic acids from even very highly dilute states, in the third step releases these in a form that, following dilution, makes them compatible with processes that amplify nucleic acids, both standard PCR as well as isothermal amplification protocols. The pre-amplification process involves ammonia solutions no more toxic than those found in the commercial product Windex, requires no electrical power, requires materials no more complex than water desalinization resin and salt, and can be used by inexperienced individuals. |
| FILED | Wednesday, February 04, 2015 |
| APPL NO | 14/613960 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6844 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106855 | Spivak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jerry L Spivak (Baltimore, Maryland); Michael Ochs (Oreland, Pennsylvania); Michael Considine (Bel Air, Maryland); Donna Rowley (Beltsville, Maryland); Alison R Moliterno (Baltimore, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides a genetic assay to determine the prognosis in Polycythemia Vera (PV) patients with an indolent form of PV. This assay involves measuring certain messenger RNAs (mRNAs) in blood cells, such as white blood cells. In some embodiments, the cells are CD34+ cells. These mRNA levels are inserted into an algorithm that yields a predictive score of the risk of PV in the patient transforming from an indolent form to an aggressive form. |
| FILED | Friday, November 08, 2013 |
| APPL NO | 14/441721 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/80 (20130101) G01N 2800/52 (20130101) G01N 2800/226 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106880 | Seghi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven Seghi (Bloomington, Indiana); Jason Kalishek (Bloomington, Indiana) |
| ABSTRACT | Embodiments disclosed herein generally relate to modifying a material's surface chemistry and surface profile using a pulsed laser. In embodiments, a system comprises: a material, the material including a surface portion having a surface chemistry; an enclosure, the enclosure containing a gaseous mixture having a non-atmospheric composition; and a pulsed laser configured to emit at least one laser pulse, the at least one laser pulse being directed to pass through the gaseous mixture onto the surface portion thereby modifying the surface chemistry of the surface portion. |
| FILED | Tuesday, March 22, 2016 |
| APPL NO | 15/077352 |
| ART UNIT | 3742 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0006 (20130101) B23K 26/14 (20130101) B23K 26/0066 (20130101) B23K 26/0084 (20130101) B23K 26/123 (20130101) B23K 26/126 (20130101) B23K 26/352 (20151001) B23K 26/0624 (20151001) B23K 2103/04 (20180801) B23K 2103/08 (20180801) B23K 2103/10 (20180801) B23K 2103/12 (20180801) B23K 2103/14 (20180801) B23K 2103/16 (20180801) B23K 2103/52 (20180801) B23K 2103/56 (20180801) B23K 2203/00 (20130101) B23K 2203/04 (20130101) B23K 2203/08 (20130101) B23K 2203/10 (20130101) B23K 2203/12 (20130101) B23K 2203/14 (20130101) B23K 2203/16 (20130101) B23K 2203/42 (20151001) B23K 2203/50 (20151001) B23K 2203/52 (20151001) B23K 2203/54 (20151001) B23K 2203/56 (20151001) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/24 (20130101) C23C 8/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107117 | Carr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Jesse M. Carr (Hartford, Connecticut); Bryan P. Dube (Columbia, Connecticut) |
| ABSTRACT | An airfoil assembly includes at least one airfoil that has a hollow interior. First and second platforms are disposed between the airfoil. At least one tie-spar extends along an axis through the first platform, the hollow interior of the airfoil, and the second platform. There is a thermal expansion difference between a thermal expansion of the tie-spar in the axial direction and the combined thermal expansion of the airfoil and the first and second platform in the axial direction. At least one spacer portion is arranged on the tie-spar. The spacer portion has a thermal expansion in the axial direction that is greater than the thermal expansion difference such that the spacer portion maintains the tie-spar under tension and clamps the first and second platforms on the airfoil. |
| FILED | Friday, August 28, 2015 |
| APPL NO | 14/838412 |
| ART UNIT | 3748 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/284 (20130101) F01D 9/041 (20130101) Original (OR) Class F01D 9/042 (20130101) F01D 25/246 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/51 (20130101) F05D 2230/60 (20130101) F05D 2230/642 (20130101) F05D 2240/12 (20130101) F05D 2240/80 (20130101) F05D 2260/31 (20130101) F05D 2300/5021 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Y02T 50/673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107128 | Romanov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Dmitriy A. Romanov (Wells, Maine); Dominic J. Mongillo, Jr. (West Hartford, Connecticut); Matthew A. Devore (Rocky Hill, Connecticut) |
| ABSTRACT | A gas turbine engine component includes a wall portion and a leading edge cooling channel that extends through the wall portion. The leading edge cooling channel includes at least one first cooling passage separated from at least one serpentine cooling passage. |
| FILED | Thursday, August 20, 2015 |
| APPL NO | 14/830812 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/08 (20130101) Original (OR) Class F01D 25/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/11 (20130101) F05D 2240/127 (20130101) F05D 2250/185 (20130101) F05D 2260/2212 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107193 | Kupratis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Daniel Bernard Kupratis (Wallingford, Connecticut); Francis R. Moon (Granby, Connecticut) |
| ABSTRACT | A gas turbine engine comprises a fan at an axially outer location, the fan rotating about an axis of rotation, delivering air into an outer bypass duct, a radially middle duct, and a radially inner core duct. Air from the inner core duct is directed into a compressor, and then flows axially in a direction back toward the fan through a combustor section, and across a core turbine section, and is then directed into the middle duct. A gear reduction drives the fan from a fan drive turbine section. A method of operating a gas turbine engine is also disclosed. |
| FILED | Wednesday, August 12, 2015 |
| APPL NO | 14/824157 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/141 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/05 (20130101) F02C 3/10 (20130101) F02C 3/13 (20130101) F02C 3/107 (20130101) F02C 3/145 (20130101) F02C 6/02 (20130101) Original (OR) Class F02C 7/36 (20130101) F02C 9/18 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) F02K 3/065 (20130101) F02K 3/075 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2220/323 (20130101) F05D 2250/36 (20130101) F05D 2260/4023 (20130101) F05D 2260/4031 (20130101) F05D 2270/053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107404 | Potter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Steve Potter (Bedford, Massachusetts); Haink Tu (Waltham, Massachusetts) |
| ABSTRACT | Examples are provided that describe a linear hydraulic valve. In one example a linear valve comprises a sleeve with a plurality of ports spaced apart from each other at a distance. The plurality of ports are associated with a plurality of pressurized fluids. A spool comprising a plurality of openings that correspond to the plurality of ports is provided within the sleeve. The plurality of openings are spaced apart in a manner that enables alignment of a given opening of the plurality of openings to a given port of the plurality of ports based on a given position of the spool within the sleeve. The linear valve comprises an actuator for moving the spool in a forward or reverse linear motion along a longitudinal axis of the sleeve. The spool may be moved to a given position based on selection of a pressurized fluid of the plurality of pressurized fluids. |
| FILED | Thursday, August 24, 2017 |
| APPL NO | 15/685680 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/0716 (20130101) Original (OR) Class F16K 31/04 (20130101) F16K 31/0613 (20130101) F16K 37/0041 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/86879 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107528 | Dodson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christoper Star Dodson (Tijeras, New Mexico) |
| ASSIGNEE(S) | The United States of America As Represented By the Secretary of The Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Christoper Star Dodson (Tijeras, New Mexico) |
| ABSTRACT | An inertance tube for a pulse tube cryogenic cooler which can be tuned to optimize performance. Apertures in the inertance tube fluidly communicate the inertance tube with a fluid reservoir. The effective length of the inertance tube is changed by alternatively closing or opening the apertures. Changing the effective length of the inertance tube causes a phase shift between the mass flow of and pressure waves in the enclosed working fluid which, in turn, changes the acoustic power. The cooling load capacity of the pulse tube cryogenic cooler is a function of the acoustic power. Controlling the phase angle improves the cooler's Carnot efficiency. |
| FILED | Tuesday, September 26, 2017 |
| APPL NO | 15/716076 |
| ART UNIT | 3744 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/145 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107554 | DeLugan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
| ASSIGNEE(S) | Hamilton Sunstrand Corporation (Windsor Locks, Connecticut) |
| INVENTOR(S) | Anthony DeLugan (Agawam, Massachusetts) |
| ABSTRACT | A heat exchange system includes a cold fluid circuit and a hot fluid circuit. The cold fluid circuit routes a cold fluid to a ram air inlet. From the ram air inlet, the cold fluid is routed to a cold fluid inlet of a heat exchanger. The cold fluid is then routed to a cold fluid outlet of the heat exchanger. The hot fluid circuit is configured to route a hot fluid. The hot fluid is routed through a bleed air valve. From the bleed air valve, the hot fluid is routed to a hot fluid inlet of the heat exchanger. The hot fluid is then routed to a hot fluid outlet of the heat exchanger. The hot fluid is then routed to a header having a first cavity and a second cavity defined within a housing and separated by a baffle. |
| FILED | Monday, June 09, 2014 |
| APPL NO | 14/299703 |
| ART UNIT | 3744 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 13/06 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/06 (20130101) Original (OR) Class F28D 9/0068 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/0214 (20130101) F28F 2265/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107607 | Burke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gregory C. Burke (Piermont, New Hampshire); John Hirlinger (Hackettstown, New Jersey); Thomas DeVoe (Randolph, New Jersey); Christopher Csernica (Port Murray, New Jersey); Viral Panchal (Parlin, New Jersey) |
| ABSTRACT | An ignition system for energetics including artillery charges includes a radio frequency transmitter and a radio frequency igniter. The radio frequency ignitor receives and converts radio frequency energy into heat or electrical energy for the purpose of igniting energetics, such as propellants or pyrotechnics. The radio frequency igniter may be applied to the exterior of the energetic container or may be integral to the container. |
| FILED | Tuesday, April 04, 2017 |
| APPL NO | 15/478557 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 19/63 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/10 (20130101) F42B 5/08 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 11/001 (20130101) F42C 13/04 (20130101) F42C 13/045 (20130101) F42C 13/047 (20130101) Original (OR) Class Blasting F42D 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107682 | Mitchell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas A. Mitchell (Nazareth, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| INVENTOR(S) | Thomas A. Mitchell (Nazareth, Pennsylvania) |
| ABSTRACT | Reflective imager sub-systems that have a non-circular entrance pupil and provide substantially increased throughput to a detecting component of a system are disclosed. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/166729 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/021 (20130101) Original (OR) Class G01J 3/024 (20130101) Optical Elements, Systems, or Apparatus G02B 17/008 (20130101) G02B 17/0615 (20130101) G02B 17/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107684 | Mitchell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wavefront Research, Inc. (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| INVENTOR(S) | Thomas A. Mitchell (Nazareth, Pennsylvania) |
| ABSTRACT | Systems and methods for increasing the overall throughput, decreasing the overall background radiation, or a combination thereof for imaging systems. |
| FILED | Tuesday, November 28, 2017 |
| APPL NO | 15/824407 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/04 (20130101) G01J 3/14 (20130101) G01J 3/18 (20130101) Original (OR) Class G01J 3/42 (20130101) G01J 3/0208 (20130101) G01J 2003/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107735 | Di Carlo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Daniel R. Gossett (Los Angeles, California); Henry T. K. Tse (San Francisco, California); Aram Chung (Los Angeles, California) |
| ABSTRACT | A system for deforming and analyzing particles includes a substrate defining an inlet, and an outlet; a fluidic pathway fluidly coupled to the inlet and the outlet and defining a delivery region upstream of a deformation region configured to deform particles, wherein the fluidic pathway comprises a first branch configured to generate a first flow, and a second branch configured to generate a second flow that opposes the first flow, wherein an intersection of the first flow and the second flow defines the deformation region; a detection module including a sensor configured to generate a morphology dataset characterizing deformation of the particles, and a photodetector configured to generate a fluorescence dataset characterizing fluorescence of the particles; and a processor configured to output an analysis of the plurality of particles based at least in part on the deformation dataset and the fluorescent dataset for the plurality of particles. |
| FILED | Tuesday, December 13, 2016 |
| APPL NO | 15/377659 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) Original (OR) Class G01N 15/1404 (20130101) G01N 15/1434 (20130101) G01N 21/64 (20130101) G01N 2015/1006 (20130101) G01N 2015/1495 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4604 (20130101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107744 | Pate et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); BrightSpec, Inc. (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); BrightSpec, Inc. (Charlottesville, Virginia) |
| INVENTOR(S) | Brooks Hart Pate (Charlottesville, Virginia); Amanda Steber (Mattoon, Illinois); Brent Harris (Charlottesville, Virginia) |
| ABSTRACT | Apparatus and techniques for broadband Fourier transform spectroscopy can include frequency hopping spread-spectrum spectroscopy approaches. For example, an excitation source power can be spread over a specified frequency bandwidth, such as by applying a sequence of short, transform-limited pulses to a sample. Each pulse can include a specified carrier frequency, and a corresponding bandwidth of the individual pulse can be determined by a frequency domain representation when Fourier transformed. A series of short excitation pulses can be used to create an excitation sequence, such as to deliver a specified or desired amount of power to the sample, such as by having the excitation source enabled for a time comparable to a free induction decay (FID) dephasing time. |
| FILED | Tuesday, June 16, 2015 |
| APPL NO | 15/319313 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) Original (OR) Class G01N 2021/3595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107749 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xiang Zhang (Alamo, California); Ren-Min Ma (Beijing, China PRC); Sadao Ota (Tokyo, Japan) |
| ABSTRACT | An active plasmon sensor comprising a single crystalline semiconductor CdS nano-slab atop a silver surface separated by a magnesium fluoride (MgF2) gap layer. The surface plasmon effect localizes the electromagnetic field at the interface between the metal and semiconductor, allowing both the device's physical size and mode confinement to shrink down to the nanometer scale in a dimension perpendicular to the metal surface. |
| FILED | Tuesday, June 07, 2016 |
| APPL NO | 15/175670 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) Original (OR) Class G01N 33/0057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107787 | Meylemans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Heather A. Meylemans (Ridgecrest, California); Alfred Baca (Ridgecrest, California); Lee R. Cambrea (Ridgecrest, California); Stephen Fallis (Ridgecrest, California) |
| ABSTRACT | A testing element, and methods of use therefor, for the detection of target analytes, for example metal ions and other environmental hazards, utilizing ligand functionalized fluorescent nanoparticles on a substrate. The non-toxic, air, and water stable fluorescent nanoparticles of the present invention are made from varying ratios of metals including zinc, silver, copper, and indium and sulfur. By varying the ratios of these metals nanoparticles can be synthesized that emit over a large range of the visible spectrum. Charge transfer between a target analyte and the nanoparticle is readily identified by a fluorescence change allowing for a fast, simple, visual detection system without the need for expensive analytical instrumentation. The test element can have more than one type of functionalized fluorescent nanoparticle which allows for the detection of multiple target analytes using a single test element. |
| FILED | Thursday, August 25, 2016 |
| APPL NO | 15/247344 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/643 (20130101) G01N 21/6428 (20130101) G01N 31/22 (20130101) G01N 33/20 (20130101) G01N 33/1813 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107858 | Gadlage et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Gadlage (Bloomington, Indiana); Adam Duncan (Bloomington, Indiana) |
| ABSTRACT | A highly flexible, compact, lightweight, and portable testing system for use with radiation testing activities. The testing system is coupled to a device under test (DUT), which can be positioned in such a way that the top of the die package is exposed to the direct ion beam during radiation testing. A variety of sensors, onboard memory systems, programmable interfaces, onboard control systems, data output devices, and different types of interfaces are also provided which provide an ability to perform testing procedures while having a maximum ability to orient the DUT and perform a wide variety of testing currently unavailable. |
| FILED | Tuesday, May 17, 2016 |
| APPL NO | 15/156807 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/302 (20130101) G01R 31/303 (20130101) Original (OR) Class G01R 31/31725 (20130101) G01R 31/31907 (20130101) Electric Digital Data Processing G06F 13/36 (20130101) G06F 13/4068 (20130101) G06F 13/4282 (20130101) Static Stores G11C 11/4125 (20130101) G11C 29/56 (20130101) G11C 2029/5002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10107891 — Wireless signal localization and collection from an airborne symmetric line array network
| US 10107891 | Ngo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Tan Anh Ngo (Auburn, Virginia); Murali Tummala (Monterey, California); John C. McEachen (Carmel, California) |
| ABSTRACT | A method and system of determining a location of a remote transmitter is provided. The method includes: receiving, with a plurality of sensors operably associated with a plurality of unmanned aerial vehicles (UAVs), a signal emitted from a remote transmitter, the emitted signal being indicative of an actual location of the remote transmitter; estimating a first location of the remote transmitter based on the emitted signal received by the plurality of sensors, the plurality of sensors being associated with a first arrangement of the corresponding plurality of UAVs relative to the remote transmitter; changing the first arrangement of the plurality of UAVs relative to the remote transmitter to a target arrangement of the plurality of UAVs relative to the remote transmitter based on the estimation of the first location of the remote transmitter; and estimating a second location of the remote transmitter based on the target arrangement of the plurality of sensors and the corresponding plurality of UAVs relative to the remote transmitter. The second estimated location is more accurate of the actual location of the remote transmitter than the first estimated location. |
| FILED | Wednesday, October 14, 2015 |
| APPL NO | 14/883384 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/06 (20130101) G01S 5/0221 (20130101) G01S 5/0278 (20130101) G01S 5/0289 (20130101) Original (OR) Class Wireless Communication Networks H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107900 | Prater, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James L. Prater, Jr. (Panama City, Florida); Jose E. Fernandez (Panama City, Florida) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James L. Prater, Jr. (Panama City, Florida); Jose E. Fernandez (Panama City, Florida) |
| ABSTRACT | A computer apparatus determines a highly accurate displacement of a sonar array in real time using multiple processors and data objects. The processors receive multiple sonar pings from a sonar array, instantiate the quasi-unique sonar objects, beamform, and update the objects using time-delay functions. Each object includes properties such as a time of flight value associated with a first ping, time-delay values associated with a second ping, a speed of sound value associated with the pair of consecutive pings, a sonar beam angle value associated with the first ping, and the displacement value. Processing code in each object utilize these properties to update the displacement value and provide it for SAS imaging. |
| FILED | Wednesday, November 30, 2016 |
| APPL NO | 15/364468 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 5/00 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52004 (20130101) Original (OR) Class G01S 15/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107907 | Nicoletti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Raytheon BBN Technologies Corporation (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael John Nicoletti (Johnston, Rhode Island); Matthew Patrick Daily (Portsmouth, Rhode Island) |
| ABSTRACT | Embodiments described herein relate to generating an image of an acoustic field associated with an underwater region. A plurality of submersible sensing devices (SSDs) are disposed so as to be substantially separate from each other in an underwater region, wherein each respective SSD is configured to execute a sink/float mission. During at least a portion of the sink/float mission, within each SSD, an environmental sensor measures at least one environmental parameter, a position sensor detects position information, an acoustic detection sensor detects at least one underwater signal, and a data recording system records mission data. After the sink/float mission, a processor receives mission data from the SSDs and generates an acoustic field image. Advantageously, during the sink/float mission some SSDs can transmit an orthogonal high time-bandwidth signal to help prevent interference between SSD during acoustic detection. |
| FILED | Monday, January 04, 2016 |
| APPL NO | 14/986968 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/20 (20130101) B63B 2201/18 (20130101) B63B 2207/02 (20130101) B63B 2211/02 (20130101) B63B 2213/02 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/003 (20130101) G01S 15/89 (20130101) Original (OR) Class Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/006 (20130101) Transmission H04B 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107924 | Bellinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RADIATION DETECTION TECHNOLOGIES, INC. (Manhattan, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven L. Bellinger (Manhattan, Kansas); Ryan G. Fronk (Manhattan, Kansas); Douglas S. McGregor (Riley, Kansas) |
| ABSTRACT | A semiconductor neutron detector and a semiconductor process is provided to manufacture a semiconductor neutron detector. First, a substrate with flat surface having a dielectric layer is formed thereon is provided. Thereafter, a masking pattern is applied and etched into the dielectric layer to expose semiconductor features on opposite sides of the substrate. The semiconductor substrate is submerged into an etchant composed of a semiconductor etching solution to etch deep cavities into the substrate in the exposed regions. Afterwards, dopant impurities are introduced and are driven into the semiconductor, under high temperature, into opposite sides of the etched features to produce one or more rectifying junctions. Afterwards, LiF and/or B particles are forced into the cavities through high velocity methods. |
| FILED | Monday, July 11, 2016 |
| APPL NO | 15/206426 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107940 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Zongfu Yu (Madison, Wisconsin); Ming Zhou (Madison, Wisconsin) |
| ABSTRACT | A resonator coupled to a system exhibiting a negative phase index of refraction presents a magnified absorption cross-section providing an optical element that can be used for enhancing taggant detection or increasing photodetector efficiency. |
| FILED | Friday, October 16, 2015 |
| APPL NO | 14/885359 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 2021/6439 (20130101) G01N 2021/6478 (20130101) Optical Elements, Systems, or Apparatus G02B 1/007 (20130101) Original (OR) Class G02B 17/002 (20130101) G02B 21/08 (20130101) G02B 21/0064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107962 | Pelc |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Jason Pelc (Palo Alto, California) |
| ABSTRACT | In the examples provided herein, an apparatus has a mode converter coupled to a first waveguide to convert light propagating in a first set of spatial modes along the first waveguide to a second set of spatial modes. The apparatus also has a second waveguide coupled to the mode converter, where the second set of spatial modes propagate along the second waveguide in a first direction away from the mode converter. Further, the apparatus includes a coupler to couple a portion of the light propagating in the second set of spatial modes out of the second waveguide. Additionally, the second waveguide has an end facet away from the mode converter to reduce back reflection of the light not coupled out of the second waveguide to the first waveguide. |
| FILED | Friday, February 20, 2015 |
| APPL NO | 15/549157 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/11 (20130101) G02B 6/14 (20130101) Original (OR) Class G02B 6/1228 (20130101) G02B 2006/1209 (20130101) G02B 2006/12107 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/295 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108539 | Almasi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Gheorghe Almasi (Ardsley, New York); Barnaby Dalton (Mississauga, Canada); Ilie G. Tanase (Somers, New York); Ettore Tiotto (Markham, Canada) |
| ABSTRACT | Allocating distributed data structures and managing allocation of a symmetric heap can include defining, using a processor, the symmetric heap. The symmetric heap includes a symmetric partition for each process of a partitioned global address space (PGAS) system. Each symmetric partition of the symmetric heap begins at a same starting virtual memory address and has a same global symmetric break. One process of a plurality of processes of the PGAS system is configured as an allocator process that controls allocation of blocks of memory for each symmetric partition of the symmetric heap. Using the processor executing the allocator process, isomorphic fragmentation among the symmetric partitions of the symmetric heap is maintained. |
| FILED | Thursday, June 13, 2013 |
| APPL NO | 13/917240 |
| ART UNIT | 2131 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/023 (20130101) Original (OR) Class G06F 2212/656 (20130101) G06F 2212/657 (20130101) G06F 2212/1024 (20130101) G06F 2212/1056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108540 | Almasi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Businiess Machines Company (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Gheorghe Almasi (Ardsley, New York); Barnaby Dalton (Mississauga, Canada); Ilie G. Tanase (Somers, New York); Ettore Tiotto (Markham, Canada) |
| ABSTRACT | Allocating distributed data structures and managing allocation of a symmetric heap can include defining, using a processor, the symmetric heap. The symmetric heap includes a symmetric partition for each process of a partitioned global address space (PGAS) system. Each symmetric partition of the symmetric heap begins at a same starting virtual memory address and has a same global symmetric break. One process of a plurality of processes of the PGAS system is configured as an allocator process that controls allocation of blocks of memory for each symmetric partition of the symmetric heap. Using the processor executing the allocator process, isomorphic fragmentation among the symmetric partitions of the symmetric heap is maintained. |
| FILED | Friday, June 14, 2013 |
| APPL NO | 13/917906 |
| ART UNIT | 2131 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/023 (20130101) Original (OR) Class G06F 2212/656 (20130101) G06F 2212/657 (20130101) G06F 2212/1024 (20130101) G06F 2212/1056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108637 | Ganti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Raghu Kiran Ganti (Elmsford, New York); Shen Li (Urbana, Illinois); Mudhakar Srivatsa (White Plains, New York) |
| ABSTRACT | A spatial-temporal storage method, system, and non-transitory computer readable medium, include, in a first layer, a geometric translation circuit configured to split spatial-temporal information into row keys and translate a geometry query into a range scan, and a multi-scan optimization circuit configured to compute an optimal read strategy to optimize the range scan translated by the geometric translation circuit into a series of block starting offsets and block sizes, and, in a second layer, a block grouping circuit configured to allow grouping of blocks in the second layer while preserving spatial data locality when splits of spatial-temporal information occur in the first layer. |
| FILED | Tuesday, March 08, 2016 |
| APPL NO | 15/064161 |
| ART UNIT | 2159 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/3087 (20130101) G06F 17/30215 (20130101) Original (OR) Class G06F 17/30427 (20130101) G06F 17/30442 (20130101) G06F 17/30581 (20130101) G06F 17/30595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108776 | Miller, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Thomas F. Miller, III (South Pasadena, California); William M. Clemons, Jr. (Pasadena, California); Stephen Marshall (Pasadena, California); Axel Mueller (Pasadena, California); Michiel Niesen (Monrovia, California); Bin Zhang (Houston, Texas) |
| ABSTRACT | Methods and systems are described to provide computerized trajectory-based methods to represent translocon-associated protein trajectories, provide proteins or protein sequences with desired translocon-associated biogenesis features, screening proteins or protein sequences to provide proteins or protein sequences with desired translocon-associated biogenesis features, screening translocon-associated biogenesis feature determinants to provide proteins or protein sequences with desired translocon-associated biogenesis features, identifying translocon-associated biogenesis feature determinants of a given protein sequence, computer-based protein sequence identification methods, computer-based methods for identifying correlations in a set of protein sequences, computer-based methods for identifying correlations between experimental data and computer-generated data in a protein sequence, and computer-based methods for determining which modifications of a protein sequence do not substantially affect a translocon-associated biogenesis feature of the protein sequence. |
| FILED | Tuesday, June 10, 2014 |
| APPL NO | 14/301069 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electric Digital Data Processing G06F 19/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108798 | Friedman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SMART INFORMATION FLOW TECHNOLOGIES LLC (Minneapolis, Minnesota) |
| ASSIGNEE(S) | SMART INFORMATION FLOW TECHNOLOGIES LLC (Minneapolis, Minnesota) |
| INVENTOR(S) | Scott Ehrlich Friedman (Minneapolis, Minnesota); David John Musliner (Plymouth, Minnesota); Peter Kelly Keller (Saint Paul, Minnesota) |
| ABSTRACT | Methods, systems, and computer-readable storage medium including a computer program product for defending against cyber-attacks are provided. One method includes receiving, by a processor, program code and automatically generating a chronomorphic binary for the program code. The method further includes storing the chronomorphic binary in an executable memory space and diversifying the executable memory space for the chronomorphic binary during runtime of the program code. A system includes memory configured for storing a defense module and a processor connected to the memory. The processor, when executing the defense module, is configured for performing the above-referenced method. One computer program product includes computer code for performing the above-referenced method. |
| FILED | Monday, January 04, 2016 |
| APPL NO | 14/987375 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 8/52 (20130101) G06F 21/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109060 | Baylog et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John G Baylog (Tiverton, Rhode Island); Russell Costa (Portsmouth, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John G Baylog (Tiverton, Rhode Island); Russell Costa (Portsmouth, Rhode Island) |
| ABSTRACT | A method for target motion analysis for calculating the track between an observer and a target and estimating its uncertainty includes initializing strongly observable state components into strong state vectors and weakly observable state components to form a weak state analysis grid. Initial probability density functions are calculated from all components. The method then iteratively calculates strong state gradients, target track direction, and updates strong state vectors over the analysis grid. Probability density functions are recalculated. Calculations are reiterated if the probability density functions change more than an information threshold. The strong state vectors and weak state probability density functions are provided as output if the information threshold is not exceeded. |
| FILED | Thursday, May 12, 2016 |
| APPL NO | 15/152696 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101) Original (OR) Class G06T 7/60 (20130101) G06T 2207/20076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109064 | Nash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Stephen R. Nash (Los Angeles, California); Christopher A. Leddy (Huntington Beach, California); Hector A. Quevedo (Redondo Beach, California) |
| ABSTRACT | A system for processing video signal information to identify those pixels associated with a moving object in the presence of platform and/or sensor pointing induced motion. Frame differencing with self-adjusting noise thresholds is implemented to detect pixels associated with objects that are in motion with respect to the background and a field-by-field motion pixel map of pixels associated with the moving object is generated. A two (2) step pixel grouping process is used where the first pass runs in real-time as the video signal is received and writes the links between pixel groups into entries in a table. The second pass operates on a smaller set of link data and only needs to reorder entries in the table. |
| FILED | Tuesday, September 01, 2015 |
| APPL NO | 15/500369 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/20 (20130101) G06T 7/74 (20170101) G06T 7/215 (20170101) Original (OR) Class G06T 2207/20128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109070 | Hecht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | James H. Hecht (Hermosa Beach, California); David W. Warren (Los Angeles, California); David J. Gutierrez (Long Beach, California) |
| ABSTRACT | An image acquisition system with motion compensation is disclosed. Embodiments of the system include: includes a rectilinear lens assembly, a first 2D-image sensor, and a motion compensation module. The rectilinear lens assembly has an optical axis, an object plane, and a focal plane. During an image acquisition cycle, the rectilinear lens assembly is positioned such that the optical axis is orthogonal to the object plane while the first 2D-image sensor is parallel to the object plane. The motion compensation module can determine a motion vector of an image scene in the object plane. In response the determined motion vector, the rectilinear lens assembly and the first 2D-image sensor relative are translated relative to each other in two dimensions to compensate for the motion of the image scene. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 15/704376 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 1/0007 (20130101) G06T 7/20 (20130101) G06T 7/579 (20170101) G06T 7/593 (20170101) Original (OR) Class G06T 2207/10012 (20130101) G06T 2207/20201 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109447 | Hoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Brad W. Hoff (Albuquerque, New Mexico); David H. Simon (Albuquerque, New Mexico); James A. Schrock (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus, system, and method for performing electron beam modulation includes an input pulser to provide an electromagnetic pulse; a radio frequency (RF) filter to filter the electromagnetic pulse; a nonlinear transmission line to receive the electromagnetic pulse, and generate a backward wave RF oscillation of a predetermined frequency to travel in a direction opposite that of the electromagnetic pulse; and an electron beam generating device including an anode and a cathode, the electron beam generating device to receive a combined electromagnetic pulse from the RF filter and the backward wave RF oscillation from the nonlinear transmission line to cause excitation of a modulated voltage between the anode and cathode, and to cause the electron beam generating device to emit an electron beam that is modulated at the predetermined frequency of the backward wave RF oscillation. |
| FILED | Thursday, May 31, 2018 |
| APPL NO | 15/994365 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 7/44 (20130101) Original (OR) Class H01J 23/04 (20130101) H01J 23/15 (20130101) H01J 2223/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109671 | Donnelly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph P Donnelly (Carlisle, Massachusetts); K Alexander McIntosh (Groton, Massachusetts); Erik K Duerr (Groton, Massachusetts); William D Goodhue (Spencer, Massachusetts); Robert J Bailey (Methuen, Massachusetts); Lisa A Wright (Chelmsford, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Joseph P Donnelly (Carlisle, Massachusetts); K Alexander McIntosh (Groton, Massachusetts); Erik K Duerr (Groton, Massachusetts); William D Goodhue (Spencer, Massachusetts); Robert J Bailey (Methuen, Massachusetts); Lisa A Wright (Chelmsford, Massachusetts) |
| ABSTRACT | There is provided an avalanche photodiode array that includes a plurality of avalanche photodiodes. Each avalanche photodiode in the array includes a stack of active photodiode materials. The stack of active photodiode materials includes a first electrical contact layer, a second electrical contact layer; an absorber material layer and an avalanche material layer each disposed between the first electrical contact layer and the second electrical contact layer; and an optical interface surface to the avalanche photodiode. The optical interface surface consists of an exposed surface of the first electrical contact layer, arranged for incident external radiation to directly enter the first electrical contact layer. Each avalanche photodiode stack of active photodiode materials is laterally isolated from the other avalanche photodiodes in the photodiode array. |
| FILED | Tuesday, May 23, 2017 |
| APPL NO | 15/602572 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2001/4466 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/11807 (20130101) H01L 27/14643 (20130101) H01L 27/14689 (20130101) Original (OR) Class H01L 31/107 (20130101) H01L 31/03529 (20130101) H01L 2027/11892 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109673 | Tolpygo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hypres, Inc. (Elmsford, New York) |
| ASSIGNEE(S) | Hypres, Inc. (Elmsford, New York) |
| INVENTOR(S) | Sergey K. Tolpygo (Putnam Valley, New York) |
| ABSTRACT | An improved microfabrication technique for Josephson junctions in superconducting integrated circuits, based on the use of a double-layer lithographic mask for partial anodization of the side-walls and base electrode of the junctions. The top layer of the mask is a resist material, and the bottom layer is a dielectric material chosen so to maximize adhesion between the resist and the underlying superconducting layer, be etch-compatible with the underlying superconducting layer, and be insoluble in the resist and anodization processing chemistries. The superconductor is preferably niobium, under a silicon dioxide layer, with a conventional photoresist or electron-beam resist as the top layer. This combination results in a substantial increase in the fabrication yield of high-density superconducting integrated circuits, increase in junction uniformity and reduction in defect density. A dry etch more compatible with microlithography may be employed. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 15/456010 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) Original (OR) Class H01L 39/12 (20130101) H01L 39/025 (20130101) H01L 39/223 (20130101) H01L 39/2406 (20130101) H01L 39/2493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109713 | Chini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); CREE INC. (Durham, North Carolina) |
| INVENTOR(S) | Alessandro Chini (Modena, Italy); Umesh Kumar Mishra (Montecito, California); Primit Parikh (Goleta, California); Yifeng Wu (Goleta, California) |
| ABSTRACT | A process for fabricating single or multiple gate field plates using consecutive steps of dielectric material deposition/growth, dielectric material etch and metal evaporation on the surface of a field effect transistors. This fabrication process permits a tight control on the field plate operation since dielectric material deposition/growth is typically a well controllable process. Moreover, the dielectric material deposited on the device surface does not need to be removed from the device intrinsic regions: this essentially enables the realization of field-plated devices without the need of low-damage dielectric material dry/wet etches. Using multiple gate field plates also reduces gate resistance by multiple connections, thus improving performances of large periphery and/or sub-micron gate devices. |
| FILED | Friday, September 30, 2016 |
| APPL NO | 15/283008 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/0605 (20130101) H01L 29/205 (20130101) H01L 29/207 (20130101) H01L 29/401 (20130101) H01L 29/402 (20130101) H01L 29/404 (20130101) Original (OR) Class H01L 29/785 (20130101) H01L 29/2003 (20130101) H01L 29/7787 (20130101) H01L 29/41766 (20130101) H01L 29/42312 (20130101) H01L 29/42316 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109754 | Shi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Zhisheng Shi (Norman, Oklahoma) |
| ABSTRACT | Disclosed is at least one embodiment of an infrared (IR) photovoltaic (PV) detector, comprising a IV-VI Lead (Pb)-salt layer disposed on a substrate and a charge-separation-junction (CSJ) structure associated with the IV-VI Pb-salt layer, wherein the CSJ structure comprises a plurality of element areas disposed upon or within the IV-VI Pb-salt layer, wherein the plurality of element areas are spaced apart from each other. Each element area may be connected to a first Ohmic contact thereby forming a plurality of interconnected first Ohmic contacts, and a second Ohmic contact may be disposed upon a portion of the IV-VI Pb-salt layer. In another non-limiting embodiment, a PV detector, comprising a heterojunction region that comprises at least one IV-VI Pb-salt material layer coupled to at least one non-Pb-salt layer, wherein the at least one IV-VI Pb-salt layer and the at least one non-Pb-salt layer form a p-n junction or Schottky junction with a type II band gap alignment. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 14/975285 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14649 (20130101) H01L 31/07 (20130101) H01L 31/0324 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109760 | Hwang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Gyuweon Hwang (Cambridge, Massachusetts); Donghun Kim (Cambridge, Massachusetts); Jose M. Cordero (Cambridge, Massachusetts); Mark W. B. Wilson (Somerville, Massachusetts); Chia-Hao M. Chuang (Cambridge, Massachusetts); Jeffrey C. Grossman (Brookline, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
| ABSTRACT | The size-dependent band-gap tunability and solution processability of nanocrystals (NCs) make them attractive candidates for optoelectronic applications. One factor that presently limits the device performance of NC thin films is sub-bandgap states, also referred to as trap states. Trap states can be controlled by surface treatment of the nanocrystals. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/095001 |
| ART UNIT | 1673 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) Original (OR) Class H01L 31/036 (20130101) H01L 31/0324 (20130101) H01L 31/0445 (20141201) H01L 31/035218 (20130101) H01L 51/0001 (20130101) H01L 51/42 (20130101) H01L 51/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109915 | Frink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew Frink (Bloomington, Indiana); George Whitaker (Albuquerque, New Mexico); Jeffrey Maas (Arlington, Virginia); Kenneth W. O'Haver (Ellicott City, Maryland) |
| ABSTRACT | A calibration method, applicable to element-level digital arrays operating in the receive mode, which utilizes the individual element plane wave spectra obtained from a single planar near-field scan. The method generates highly accurate near-field measurement derived amplitude and phase calibration of both large and small digital arrays as a function of array scan. The present disclosure provides digital array calibration methods and their potential uses in satellites and directional arrays. |
| FILED | Friday, February 13, 2015 |
| APPL NO | 14/622777 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/267 (20130101) Original (OR) Class Transmission H04B 17/12 (20150115) H04B 17/21 (20150115) Technical Subjects Covered by Former US Classification Y10T 29/49005 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10109924 — Method for assembling a multi-element apparatus using a reconfigurable assembly apparatus
| US 10109924 | Waters |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey M. Waters (Solsberry, Indiana) |
| ABSTRACT | Systems and methods for assembling different multi-element items with different specifications using a reconfigurable apparatus are provided. One embodiment includes a base plate, a back plate coupled to the base plate in a predetermined angle relationship. The exemplary back plate comprises a plurality of alignment pins adapted to engage with alignment locations of multiple element assembly items. The exemplary base plate and alignment mounting structures couple to end cap parts disposed on opposing ends of the multiple element assembly items holding the items together. A clamping mechanism maintains/releases pressure on the multiple element assembly items against the back plate. The back plate holds alignment pins in a first back plate location in a first orientation for one type of multiple element assembly items and hold the alignment pins in a second location when the back plate is in a second orientation for a different type of multiple element assembly items. |
| FILED | Tuesday, January 31, 2017 |
| APPL NO | 15/420218 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 5/12 (20130101) B25B 11/02 (20130101) Antennas, i.e Radio Aerials H01Q 1/1207 (20130101) H01Q 13/0283 (20130101) Original (OR) Class H01Q 21/064 (20130101) H01Q 21/0087 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4902 (20150115) Y10T 29/49016 (20150115) Y10T 29/49899 (20150115) Y10T 29/53961 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109925 | Mozaffar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nazia A. Mozaffar (San Diego, California); John Harold Meloling (San Diego, California); David Hurdsman (Spring Valley, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nazia A. Mozaffar (San Diego, California); John Harold Meloling (San Diego, California); David Hurdsman (Spring Valley, California) |
| ABSTRACT | A dual feed slot antenna can include a ground plane formed with an aperture, and first feed and second feeds extending into the aperture. The first feed and second feed can extend into the aperture so that the first feed and second feed are coincident and out of phase with other. The first feed and said second feed can define a U-shaped stub, with a respective stub length, a stub width, a crossbar and a pair of stub tines defining a stub separation extending from the crossbar. The first feed and second feed can extend into the aperture so that each of the stub tines from a first feed are coincident the stub tines from the second feed. With this configuration, and with further selection of the said respective stub lengths, stub widths and stub separations, a symmetric omnidirectional radiation can be established for the antenna. |
| FILED | Monday, August 15, 2016 |
| APPL NO | 15/236535 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 1/48 (20130101) H01Q 5/35 (20150115) H01Q 5/40 (20150115) H01Q 5/42 (20150115) H01Q 5/45 (20150115) H01Q 9/0407 (20130101) H01Q 13/10 (20130101) Original (OR) Class H01Q 13/18 (20130101) H01Q 13/106 (20130101) H01Q 21/29 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109970 | Slipper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael E. Slipper (Ridley Park, Pennsylvania); Tristan M. Wolfe (Philadelphia, Pennsylvania); Daniel J. Simmons (Tucson, Arizona) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael E. Slipper (Ridley Park, Pennsylvania); Tristan M. Wolfe (Philadelphia, Pennsylvania); Daniel J. Simmons (Tucson, Arizona) |
| ABSTRACT | The disclosed invention is a slip ring assembly that provides electrical power transfer to centrifugal turbomachinery while minimizing or eliminating the presence of wires in the flow path. The device transfers electrical power through a set of wires connected to a plurality of brushes that are held rotationally stationary, but allowed to displace axially or radially through a set of springs. The brushes make contact with conductive busbar rings, transferring electricity to the busbar rings. The busbar rings rotate with the centrifugal turbomachine with a set of wires that connect the busbar rings to the blades or other aerodynamic surfaces of the centrifugal turbomachine. |
| FILED | Tuesday, May 23, 2017 |
| APPL NO | 15/602983 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 39/08 (20130101) H01R 39/10 (20130101) H01R 39/381 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10110261 | White et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Douglas W. White (Lexington, Massachusetts); Seth M. Davis (Lexington, Massachusetts) |
| ABSTRACT | A method of adapting an antenna to a transceiver system having a receiver subsystem and a transmitter subsystem comprises using an automatic tuning system to tune the antenna with respect to the receiver subsystem. The tuning results in an optimal receive signal at the receiver subsystem in response to RF energy radiated to the antenna. The tuning system may include a tuning detection element for radiating RF energy to the antenna, and a tuning element for tuning the antenna. After tuning the antenna, the method further comprises tuning a tunable matching network, coupled between an output of an RF power device of the transmitter subsystem and an input of the antenna, to facilitate an optimal power transfer amount from the RF power device to the antenna while the RF power device operates according to certain desired parameters. The desired parameters may include output power and efficiency. |
| FILED | Wednesday, April 05, 2017 |
| APPL NO | 15/479414 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/14 (20130101) H04B 1/40 (20130101) H04B 1/0458 (20130101) Original (OR) Class H04B 17/102 (20150115) H04B 2001/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10110370 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Marsh Rice University (, None) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Charles Chen (Houston, Texas); Aydin Babakhani (Houston, Texas) |
| ABSTRACT | Systems and methods providing wireless synchronization of wave arrays may include an antenna that receives a wireless injection signal and another antenna that radiates a locked wave signal corresponding to the injection signal. In some embodiments, these systems may also provide a low noise amplifier, voltage controlled oscillator (VCO), buffer amplifier(s), phase shifter, and/or multi-stage amplifier. In some embodiments, the injection signal may be provided on an even harmonic, and the intended transmission frequency signal is on an odd harmonic of the locked signal. The substrate thickness may be designed to radiate electromagnetic waves in odd harmonics of the locked signal. In yet another embodiment, polarization of a receiving antenna may be orthogonal to a transmitter antenna. |
| FILED | Tuesday, May 17, 2016 |
| APPL NO | 15/156965 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1852 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/24 (20130101) Transmission H04B 1/40 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/033 (20130101) H04L 7/0079 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10110856 | Rasheed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AVIGILON FORTRESS CORPORATION (Vancouver, Canada) |
| ASSIGNEE(S) | AVIGILON FORTRESS CORPORATION (Vancouver, Canada) |
| INVENTOR(S) | Zeeshan Rasheed (Herndon, Virginia); Dana Eubanks (Herndon, Virginia); Weihong Yin (Great Falls, Virginia); Zhong Zhang (Great Falls, Virginia); Kyle Glowacki (Reston, Virginia); Allison Beach (Leesburg, Virginia) |
| ABSTRACT | Systems, methods and computer-readable media for creating and using video analysis rules that are based on map data are disclosed. A sensor(s), such as a video camera, can track and monitor a geographic location, such as a road, pipeline, or other location or installation. A video analytics engine can receive video streams from the sensor, and identify a location of the imaged view in a geo-registered map space, such as a latitude-longitude defined map space. A user can operate a graphical user interface to draw, enter, select, and/or otherwise input on a map a set of rules for detection of events in the monitored scene, such as tripwires and areas of interest. When tripwires, areas of interest, and/or other features are approached or crossed, the engine can perform responsive actions, such as generating an alert and sending it to a user. |
| FILED | Friday, December 04, 2015 |
| APPL NO | 14/959919 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00771 (20130101) G06K 9/3241 (20130101) G06K 9/6255 (20130101) Image Data Processing or Generation, in General G06T 17/05 (20130101) G06T 2207/30232 (20130101) G06T 2219/2004 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/19671 (20130101) Pictorial Communication, e.g Television H04N 7/181 (20130101) Original (OR) Class H04N 7/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10111031 | Blowers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESETNED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Misty Blowers (Minoa, New York); Baek-Young Choi (Overland Park, Kansas); Sejun Song (Overland Park, Kansas); Jonathan Williams (Rome, New York) |
| ABSTRACT | A system and method for automated crowd sensing object detection. The invention senses a missing object's presence in proximity which is conducted using a smartphone, with a software application running in the background that opportunistically collects and reports the data without the active involvement of the user. A small tag is attached to a tracked object or worn by a person who does not carry a smartphone (i.e., a young child), and emits a secure wireless signal periodically for geo-fencing and geo-tracking by caregivers. The information is sent to a cloud server so that the commander may be able to confirm the whereabouts of the tagged object or person in this case. |
| FILED | Friday, January 22, 2016 |
| APPL NO | 15/003899 |
| ART UNIT | 2642 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 67/42 (20130101) Wireless Communication Networks H04W 4/06 (20130101) H04W 4/021 (20130101) Original (OR) Class H04W 8/005 (20130101) H04W 84/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10111094 | Ramsey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin W Ramsey (Dayton, Ohio); Barry E Mullins (Beavercreek, Ohio) |
| ABSTRACT | A method of establishing a hardware identity of a coordinating device in a wireless network is provided. A standard PHY preamble is modified to a preamble that can be received by the coordinating device having an expected hardware configuration. The modified PHY preamble is transmitted with an association request by a joining device. In response to not receiving a reply containing an association response from the coordinating device by the joining device, determining the hardware configuration of the coordinating device is not the expected hardware configuration. A further method of characterizing a hardware identity of a device in a wireless network is also provided. A request with a modified PHY preamble is transmitted to a device. If a reply is received from the device, characterizing the device as a first hardware type. And, if a reply is not received, characterizing the device as not the first hardware type. |
| FILED | Friday, August 14, 2015 |
| APPL NO | 14/826597 |
| ART UNIT | 2416 — Multiplex and VoIP |
| CURRENT CPC | Wireless Communication Networks H04W 4/80 (20180201) H04W 12/06 (20130101) Original (OR) Class H04W 12/12 (20130101) H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D831748 | Fea et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Michael J. Fea (Lorton, Virginia); Amy J. Dalmas (Manassas, Virginia); Sharon Carrillo (San Antonio, Texas) |
| ABSTRACT | |
| FILED | Friday, December 01, 2017 |
| APPL NO | 29/628077 |
| ART UNIT | 2913 — Design |
| CURRENT CPC | Games, toys, and sports goods D21/376 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10105751 | Lesperance |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Joseph Larry Lesperance (Kansas City, Missouri) |
| ABSTRACT | A rivet dispenser and method for manually loading a handheld rivet gun. The handheld rivet gun may include an attachment port, and the rivet dispenser may have a unitary, single-piece tool body having channels formed therein, sized and shaped to retain heads of a plurality of rivets. The method may include grasping the rivet dispenser in a first hand, grasping the rivet gun in a second hand, and inserting an end of one rivet, extending outward from the rivet dispenser, into the attachment port, thus attaching the rivet to the handheld rivet gun. The method may then include sliding the one rivet through and out of the channel of the rivet dispenser, via movement of the rivet gun and/or the rivet dispenser. Finally, the method may include actuating the rivet gun to install the one rivet into a hole of a structure or structures to be joined together thereby. |
| FILED | Thursday, December 10, 2015 |
| APPL NO | 14/965621 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 15/32 (20130101) B21J 15/38 (20130101) Original (OR) Class B21J 15/043 (20130101) B21J 15/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105867 | Dooley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Forest Concepts, LLC (Auburn, Washington) |
| ASSIGNEE(S) | Forest Concepts, LLC (Auburn, Washington) |
| INVENTOR(S) | James H. Dooley (Federal Way, Washington); David N. Lanning (Federal Way, Washington) |
| ABSTRACT | Comminution process of wood chips to produce wood particles, by feeding wood chips in a direction of travel substantially normal to grain through a counter rotating pair of intermeshing arrays of cutting discs arrayed axially perpendicular to the direction of wood chip travel, wherein the cutting discs have a uniform thickness (Td), to produce wood particles characterized by a length dimension (L) substantially equal to the Td and aligned substantially parallel to grain, a width dimension (W) normal to L and aligned cross grain, and a height dimension (H) aligned normal to W and L, wherein the W×H dimensions define a pair of substantially parallel end surfaces with crosscut fibers. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/444983 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Removing Bark or Vestiges of Branches; Splitting Wood; Manufacture of Veneer, Wooden Sticks, Wood Shavings, Wood Fibres or Wood Powder B27L 11/00 (20130101) Original (OR) Class B27L 11/02 (20130101) Fibrous Raw Materials or Their Mechanical Treatment D21B 1/061 (20130101) D21B 1/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105876 | Lind et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U T-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Randall F. Lind (Loudon, Tennessee); Brian K Post (Knoxville, Tennessee); Phillip C. Chesser (Knoxville, Tennessee); Andrew P. Reis (Knoxville, Tennessee); Alex C. Roschli (Kingston, Tennessee) |
| ABSTRACT | An apparatus 20 and a method 100 for generating and dispensing a powdered 60 release agent during an additive manufacturing build is disclosed. A solid body 28 of release agent material is ground insitu by a grinder 50 and dispensed on a surface of the part 72 to prevent adhesion of an adjacent layer of a base material 70. With the addition of the powdered 60 release agent, a support structure 76 is easily separated from the base material 70 when the part 72 is complete, saving time and preventing the part 72 from sustaining unintentional damage. Since no powdered 60 release agent is actually loaded or stored in the apparatus 20, the potential for spillage, waste, inconsistent dispensing, inadvertent dispensing, and clumping due to humidity is eliminated. |
| FILED | Monday, December 07, 2015 |
| APPL NO | 14/960647 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 37/0071 (20130101) Original (OR) Class B29C 64/40 (20170801) B29C 64/205 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 40/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106407 | Siriwardane et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Ranjani V. Siriwardane (Morgantown, West Virginia); Yueying Fan (Morgantown, West Virginia) |
| ABSTRACT | Materials, methods to prepare, and methods of use for partial oxidation of methane. Embodiments include delivering a metal ferrite oxygen carrier to a fuel reactor, wherein the metal ferrite oxygen carrier comprises MFexOy where 1≤x≤3 and 3≤y≤5, and where M comprise a Group II alkali earth metals; and delivering a gaseous stream that contains methane to the metal ferrite oxygen carrier in the fuel reactor and maintaining the fuel reactor at a reducing temperature sufficient to reduce some portion of the metal ferrite oxygen carrier and oxidize some portion of the methane containing gas stream. Embodiments further include generating gaseous products containing H2 and CO gas in the fuel reactor; withdrawing a product stream from the fuel reactor, where the gaseous products comprise the product stream, and where at least >50 vol. % of the product stream includes CO and H2; oxidizing the reduced carrier in an oxidizing reactor by contacting the reduced carrier and an oxidizing gas at an oxidizing temperature, where the oxidizing gas is comprised of oxygen, and where the oxidizing temperature is sufficient to generate an oxidizing reaction, where the reactants of the oxidizing reaction comprise some portion of the oxygen, some portion of the M component, and some portion of the FecOd component, and further wherein the product of the oxidizing reaction is a re-oxidized carrier that comprises some portion of the MFexOy; and delivering heat generated in the oxidizing reactor to the fuel reactor for the reaction of metal ferrite with methane. |
| FILED | Wednesday, April 26, 2017 |
| APPL NO | 15/497708 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/78 (20130101) B01J 23/94 (20130101) B01J 38/12 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) Original (OR) Class C01B 2203/0261 (20130101) C01B 2203/1047 (20130101) C01B 2203/1241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106418 | Pauzauskie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Peter J. Pauzauskie (Oakland, California); Marcus A. Worsley (Hayward, California); Theodore F. Baumann (Discovery Bay, California); Joe H. Satcher, Jr. (Patterson, California); Juergen Biener (San Leandro, California) |
| ABSTRACT | Graphene aerogels with high conductivity and surface areas including a method for making a graphene aerogel, including the following steps: (1) preparing a reaction mixture comprising a graphene oxide suspension and at least one catalyst; (2) curing the reaction mixture to produce a wet gel; (3) drying the wet gel to produce a dry gel; and (4) pyrolyzing the dry gel to produce a graphene aerogel. Applications include electrical energy storage including batteries and supercapacitors. |
| FILED | Tuesday, January 27, 2015 |
| APPL NO | 14/606894 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0446 (20130101) Original (OR) Class C01B 32/00 (20170801) C01B 32/184 (20170801) C01B 32/194 (20170801) C01B 32/336 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/12 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/734 (20130101) Y10S 977/842 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) Y10T 428/268 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106727 | Cannan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia LLC (Albuquerque, New Mexico); CARBO Ceramics Inc. (Houston, Texas); STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); CARBO Ceramics Inc. (Houston, Texas); STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Chad Cannan (Cypress, Texas); Terrence Palisch (Richardson, Texas); Richard A. Kemp (Albuquerque, New Mexico); Timothy J. Boyle (Albuquerque, New Mexico); Bernadette A. Hernandez-Sanchez (Albuquerque, New Mexico); James E. Miller (Albuquerque, New Mexico) |
| ABSTRACT | Proppant compositions for use in hydraulic fracturing and methods of using same are disclosed herein. The proppant compositions include a plurality of proppant particulates and at least one particulate of the plurality of proppant particulates containing at least one tracer, wherein the at least one tracer separates from the at least one particulate located inside a fracture of a subterranean formation after a period of time. |
| FILED | Wednesday, September 17, 2014 |
| APPL NO | 14/488989 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/80 (20130101) Original (OR) Class C09K 8/805 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/267 (20130101) E21B 47/1015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106807 | Muchero et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee); West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee); WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia) |
| INVENTOR(S) | Wellington Muchero (Oak Ridge, Tennessee); Jay Chen (Oak Ridge, Tennessee); Lee E. Gunter (Oak Ridge, Tennessee); Sara Jawdy (Oak Ridge, Tennessee); Gerald A. Tuskan (Oak Ridge, Tennessee); Anthony Christian Bryan (Knoxville, Tennessee); Stephen Difazio (Morgantown, West Virginia); Hao-Bo Guo (Oak Ridge, Tennessee) |
| ABSTRACT | The invention provides plants having desirable levels of sugar release and/or lignin synthesis. The invention further provides methods of selecting plants with such desirable levels of sugar release and/or lignin synthesis; methods of genetically modifying plants to modulate lignin synthesis, sugar release, and modulating phenylalanine, tyrosine, tryptophan and flavonoid production; and uses of such plants. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 14/720023 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1092 (20130101) C12N 15/8218 (20130101) C12N 15/8246 (20130101) C12N 15/8251 (20130101) C12N 15/8254 (20130101) C12N 15/8255 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106809 | Sayre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Richard T. Sayre (Los Alamos, New Mexico); Sowmya Subramanian (Los Alamos, New Mexico); Edgar Cahoon (Lincoln, Nebraska) |
| ABSTRACT | Disclosed herein are transgenic cells expressing a heterologous nucleic acid encoding a prephenate dehydrogenase (PDH) protein, a heterologous nucleic acid encoding a homogentisate solanesyl transferase (HST) protein, a heterologous nucleic acid encoding a deoxyxylulose phosphate synthase (DXS) protein, or a combination of two or more thereof. In particular examples, the disclosed transgenic cells have increased plastoquinone levels. Also disclosed are methods of increasing cell growth rates or production of biomass by cultivating transgenic cells expressing a heterologous nucleic acid encoding a PDH protein, a heterologous nucleic acid encoding an HST protein, a heterologous nucleic acid encoding a DXS protein, or a combination of two or more thereof under conditions sufficient to produce cell growth or biomass. |
| FILED | Thursday, December 22, 2016 |
| APPL NO | 15/389061 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8261 (20130101) Original (OR) Class Enzymes C12Y 103/01012 (20130101) C12Y 202/01007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106813 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Kyung-Hwan Han (Okemos, Michigan); Won-Chan Kim (Okemos, Michigan); Joo-Yeol Kim (Lansing, Michigan); Jae-Heung Ko (Suwon, South Korea) |
| ABSTRACT | Drought-inducible plant promoters are described herein that are useful for expressing drought tolerance factors in plants. |
| FILED | Monday, February 09, 2015 |
| APPL NO | 14/617061 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/8237 (20130101) C12N 15/8273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106903 | Motsegood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Perry N. Motsegood (Shorewood, Illinois); James L. Willit (Batavia, Illinois); Mark A. Williamson (Naperville, Illinois); Stanley G. Wiedmeyer (Glen Ellyn, Illinois); Eugene R. Koehl (Joliet, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Perry N. Motsegood (Shorewood, Illinois); James L. Willit (Batavia, Illinois); Mark A. Williamson (Naperville, Illinois); Stanley G. Wiedmeyer (Glen Ellyn, Illinois); Eugene R. Koehl (Joliet, Illinois) |
| ABSTRACT | An anode assembly is provided having a pair of channels; anodes in slidable communication with the channels; conduit to direct carrier gas to the anode; and conduit to remove reaction gas from the anode. Also provided is a method for continuously feeding anodes into a electrolytic bath, the method having the steps of stacking the anodes such that all of the anodes reside in the same plane and wherein the stack includes a bottom anode; contacting the bottom anode with the electrolytic bath for a time and at a current sufficient to cause the bottom anode to be consumed during an electrolytic process; using gravity to replace the bottom anode with other anodes defining the stack. |
| FILED | Tuesday, March 08, 2016 |
| APPL NO | 15/064106 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/22 (20130101) C25C 3/34 (20130101) C25C 7/02 (20130101) C25C 7/06 (20130101) C25C 7/007 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106911 | Carlson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Varian Semiconductor Equipment Associates, Inc. (Gloucester, Massachusetts) |
| ASSIGNEE(S) | VARIAN SEMICONDUCTOR EQUIPMENT ASSOCIATES, INC. (Gloucester, Massachusetts) |
| INVENTOR(S) | Frederick M. Carlson (Potsdam, New York); Brian T. Helenbrook (Potsdam, New York) |
| ABSTRACT | An apparatus for growing a silicon crystal substrate comprising a heat source, an anisotropic thermal load leveling component, a crucible, and a cold plate component is disclosed. The anisotropic thermal load leveling component possesses a high thermal conductivity and may be positioned atop the heat source to be operative to even-out temperature and heat flux variations emanating from the heat source. The crucible may be operative to contain molten silicon in which the top surface of the molten silicon may be defined as a growth interface. The crucible may be substantially surrounded by the anisotropic thermal load leveling component. The cold plate component may be positioned above the crucible to be operative with the anisotropic thermal load leveling component and heat source to maintain a uniform heat flux at the growth surface of the molten silicon. |
| FILED | Tuesday, October 04, 2016 |
| APPL NO | 15/284767 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 15/06 (20130101) Original (OR) Class C30B 15/007 (20130101) C30B 15/14 (20130101) C30B 15/22 (20130101) C30B 15/30 (20130101) C30B 15/206 (20130101) C30B 15/305 (20130101) C30B 29/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 117/1024 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
10106913 — System for growth of large aluminum nitride single crystals with thermal-gradient control
| US 10106913 | Bondokov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert T. Bondokov (Watervliet, New York); Shailaja P. Rao (Albany, New York); Shawn Robert Gibb (Clifton Park, New York); Leo J. Schowalter (Latham, New York) |
| ASSIGNEE(S) | CRYSTAL IS, INC. (Green Island, New York) |
| INVENTOR(S) | Robert T. Bondokov (Watervliet, New York); Shailaja P. Rao (Albany, New York); Shawn Robert Gibb (Clifton Park, New York); Leo J. Schowalter (Latham, New York) |
| ABSTRACT | In various embodiments, non-zero thermal gradients are formed within a growth chamber both substantially parallel and substantially perpendicular to the growth direction during formation of semiconductor crystals, where the ratio of the two thermal gradients (parallel to perpendicular) is less than 10, by, e.g., arrangement of thermal shields outside of the growth chamber. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 15/410915 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/002 (20130101) C30B 23/06 (20130101) Original (OR) Class C30B 23/025 (20130101) C30B 29/403 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107132 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Xin Wu (East Hartford, Connecticut); Nicholas Charles Soldner (Southbury, Connecticut); Cagatay Tokgoz (East Hartford, Connecticut); Joseph V. Mantese (Ellington, Connecticut); Joseph Zacchio (Wethersfield, Connecticut) |
| ABSTRACT | A magnetic communication system for a gas turbine engine may include a sensor coupled to a microcontroller. A low frequency radio-frequency identification integrated chip may be coupled to the microcontroller. A first coupling circuit may be coupled to the low frequency radio-frequency identification integrated chip and may include a first coil winding wound within a first core. The first coil winding operatively associated with a low frequency magnetic flux. |
| FILED | Tuesday, May 05, 2015 |
| APPL NO | 14/704715 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/28 (20130101) F01D 17/02 (20130101) F01D 17/20 (20130101) F01D 21/003 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/507 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/07771 (20130101) G06K 19/07777 (20130101) Selecting H04Q 9/00 (20130101) H04Q 2209/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107268 | Ambrosini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Andrea Ambrosini (Albuquerque, New Mexico); James E. Miller (Albuquerque, New Mexico); David D. Gill (Bellingham, Washington) |
| ABSTRACT | A solar power system and materials capable of storing heat energy by thermochemical energy storage are disclosed. Thermal energy is stored as chemical potential in these materials through a reversible reduction-oxidation reaction. Thermal energy from concentrated sunlight drives a highly endothermic reduction reaction that liberates lattice oxygen from the oxide to form O2 gas, leaving energy-rich, oxygen-depleted particles. When desired, the heat is recovered as the particles are re-oxidized in an exothermic reaction upon exposure to air. The system may be integrated with a power generation system to generate power. |
| FILED | Friday, September 04, 2015 |
| APPL NO | 14/846201 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 6/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107270 | Marion, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livemore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | John E. Marion, III (Livemore, California); Jane P. Bearinger (Livermore, California); Thomas S. Wilson (San Leandro, California); Ward Small, IV (Livemore, California); Duncan J. Maitland (College Station, Texas) |
| ABSTRACT | A resistively heated shape memory polymer device is operated using resistive heating to heat the shape memory polymer device. The resistively heated shape memory polymer device is made by providing a wire that includes a resistive medium. The wire is coated with a first shape memory polymer. The wire is exposed and electrical leads are attached to the wire. In one embodiment the shape memory polymer device is in the form of a clot destruction device. In another embodiment the shape memory polymer device is in the form of a microvalve. In another embodiment the shape memory polymer device is in the form of a micropump. In yet another embodiment the shape memory polymer device is in the form of a thermostat or relay switch. |
| FILED | Thursday, February 25, 2016 |
| APPL NO | 15/053293 |
| ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3207 (20130101) A61B 17/320725 (20130101) A61B 2017/00867 (20130101) A61B 2017/22084 (20130101) A61B 2017/22094 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) Original (OR) Class Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 31/025 (20130101) F16K 99/0005 (20130101) F16K 99/0038 (20130101) F16K 99/0044 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 37/46 (20130101) H01H 37/323 (20130101) H01H 2205/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107296 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| ASSIGNEE(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| INVENTOR(S) | Harold Huimin Sun (West Bloomfield, Michigan); Dave R. Hanna (Troy, Michigan); Thomas Polley (Livonia, Michigan); Liangjun Hu (Dearborn, Michigan); Daniel William Kantrow (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods are provided for a turbocharger compressor, where the system may comprise: an actuatable annular disk comprising choke slots therein; an outer annular disk comprising choke slots therein; and an actuator to rotate the actuatable annular disk relative to the outer annular disk to vary alignment of the choke slots of the actuatable annular disk and the outer annular disk. The actuator may be controlled by an engine controller responsive to operating conditions of the compressor and actuated to align choke slots. Alignment of the choke slots allows air to be drawn into the impeller effectively expanding the compressor flow capacity to prevent compressor choke. |
| FILED | Tuesday, June 25, 2013 |
| APPL NO | 13/926949 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/148 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/12 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 26/05 (20160201) F02M 26/06 (20160201) Non-positive-displacement Pumps F04D 27/0207 (20130101) F04D 27/0215 (20130101) F04D 27/0246 (20130101) Original (OR) Class F04D 29/464 (20130101) F04D 29/685 (20130101) F04D 29/4213 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107452 | Griffith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | Other Lab, LLC (San Francisco, California) |
| INVENTOR(S) | Saul Griffith (San Francisco, California); Peter S. Lynn (San Francisco, California); Samuel Eli Calisch (San Francisco, California); Tucker Gilman (San Francisco, California); Kevin Simon (San Francisco, California) |
| ABSTRACT | A system for storing natural gas comprises a plurality of straight sections of tube. The plurality of straight sections of tube are dense packed. The plurality of straight sections of tube are configured to fill a designated volume. |
| FILED | Tuesday, August 09, 2016 |
| APPL NO | 15/232355 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 15/03006 (20130101) B60K 2015/03315 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/00 (20130101) F17C 1/005 (20130101) Original (OR) Class F17C 2201/054 (20130101) F17C 2201/056 (20130101) F17C 2201/0109 (20130101) F17C 2201/0123 (20130101) F17C 2201/0138 (20130101) F17C 2203/0636 (20130101) F17C 2203/0646 (20130101) F17C 2203/0673 (20130101) F17C 2205/0107 (20130101) F17C 2205/0111 (20130101) F17C 2205/0115 (20130101) F17C 2205/0134 (20130101) F17C 2205/0352 (20130101) F17C 2209/221 (20130101) F17C 2209/2181 (20130101) F17C 2221/033 (20130101) F17C 2223/0123 (20130101) F17C 2260/018 (20130101) F17C 2270/0168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107564 | Mathur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Terrafore Technologies, LLC (Minneapolis, Minnesota); Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | Terrafore Technologies, LLC (Minneapolis, Minnesota); Southwest Research Institute (San Antonio, Texas) |
| INVENTOR(S) | Anoop Kumar Mathur (Shoreview, Minnesota); Rajan Babu Kasetty (Riverside, California); James D. Oxley (Helotes, Texas) |
| ABSTRACT | Methods of encapsulating a phase change material in a capsule including suspending a particle of the phase change material in an air stream, coating an entire surface of the suspended particle with at least one layer of a sacrificial compound, coating an entire surface of the layer of the sacrificial compound with at least one layer of a second material, and encapsulating the phase change material within a shell formed by the second material. The step of encapsulating comprising heating the particle coated with the sacrificial compound and the second material, thermally decomposing the sacrificial compound, and vaporizing the sacrificial, wherein the sacrificial compound has a decomposition temperature less than a phase change temperature of the phase change material and a phase change temperature of the second material. |
| FILED | Monday, August 22, 2016 |
| APPL NO | 15/243537 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 5/06 (20130101) B65B 29/00 (20130101) B65B 51/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/063 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/023 (20130101) Original (OR) Class F28D 20/028 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107696 | Santhanagopalan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Shriram Santhanagopalan (Lakewood, Colorado); Matthew Allen Keyser (Arvada, Colorado); Aron Ray Saxon (Golden, Colorado); John Ireland (Sunnyvale, Colorado) |
| ABSTRACT | The present disclosure provides a calorimeter device and an electrochemical system analysis method. The device includes a first thermo-electric gauge (TEG) and a first conductor thermally coupled to the first TEG, the first conductor comprising a first surface. The device may also include a second conductor with a second surface, the second surface facing the first surface, thereby forming a gap. The device may also include a second TEG thermally coupled to the second conductor and an adjustment mechanism attached to the second TEG, operable to modify a size of the gap between the first surface and the second surface. The method includes applying a plurality of electrical signals across an electrochemical system, determining, using a calorimeter, at least one rate at which heat is generated by the system, and determining at least one thermal characteristic of a component of the system. |
| FILED | Wednesday, September 16, 2015 |
| APPL NO | 14/855538 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/20 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/4285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107937 | Kasevich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AOSense, Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | AOSense, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Mark A. Kasevich (Palo Alto, California); Miroslav Y. Shverdin (Mountain View, California); Adam T. Black (Mountain View, California); Todd L. Gustavson (Sunnyvale, California) |
| ABSTRACT | A system for gravity measurement includes one or more atom sources, two or more laser beams, and a polarizing beamsplitter and a retro-reflection prism assembly. The one or more atom sources is to provide three ensembles of atoms. The two or more laser beams is to cool or interrogate the three ensembles of atoms. The polarizing beamsplitter and the retro-reflection prism assembly are in a racetrack configuration. The racetrack configuration routes the two or more laser beams in opposing directions around a loop topology, intersecting the three ensembles of atoms with appropriate polarizations chosen for cooling or interferometer interrogation. The three ensembles of atoms are positioned coaxially when interrogated. |
| FILED | Friday, December 18, 2015 |
| APPL NO | 14/975174 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 7/00 (20130101) G01V 7/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109381 | Harp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC. (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Jason Michael Harp (Idaho Falls, Idaho); Paul Alan Lessing (Idaho Falls, Idaho); Rita Elaine Hoggan (Idaho Falls, Idaho) |
| ABSTRACT | A method of forming a triuranium disilicide structure comprises forming a mixture comprising uranium particles and silicon particles. The mixture is pressed to form a compact comprising the uranium particles and the silicon particles. The compact is subjected to an arc melting process to form a preliminary triuranium disilicide structure. The preliminary triuranium disilicide structure is subjected to a comminution process to form a fine triuranium disilicide powder. The fine triuranium disilicide powder is pressed to form a green triuranium disilicide structure. The green triuranium disilicide structure is then sintered. Additional methods of forming a triuranium disilicide structure are also described, as are fuel rods for light water reactors. |
| FILED | Monday, June 22, 2015 |
| APPL NO | 14/746279 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/65 (20130101) C04B 35/634 (20130101) C04B 35/653 (20130101) C04B 35/5158 (20130101) C04B 35/6261 (20130101) C04B 35/58085 (20130101) C04B 2235/77 (20130101) C04B 2235/3891 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/6562 (20130101) C04B 2235/6567 (20130101) C04B 2235/6581 (20130101) Nuclear Reactors G21C 3/04 (20130101) G21C 3/58 (20130101) G21C 21/02 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109418 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jun Cui (Richland, Washington); Glenn J. Grant (Benton City, Washington); Saumyadeep Jana (Kennewick, Washington); Yuri Hovanski (West Richland, Washington); Curt A. Lavender (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Jun Cui (Richland, Washington); Glenn J. Grant (Benton City, Washington); Saumyadeep Jana (Kennewick, Washington); Yuri Hovanski (West Richland, Washington); Curt A. Lavender (Richland, Washington) |
| ABSTRACT | A die tool and process are described that provide friction consolidation fabrication and friction consolidation extrusion fabrication products including permanent magnets, and other extrusion and non-extrusion structures. The present invention overcomes previous particle size, texture, homogeneity and density limitations in conventional metallurgy processes. |
| FILED | Friday, May 02, 2014 |
| APPL NO | 14/268216 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/04 (20130101) B29C 43/34 (20130101) B29C 43/52 (20130101) B29C 43/56 (20130101) B29C 43/361 (20130101) B29C 2043/043 (20130101) B29C 2043/568 (20130101) B29C 2043/3433 (20130101) B29C 2043/3636 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 41/0266 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109453 | Stevens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Andrew J. Stevens (Richland, Washington); Libor Kovarik (West Richland, Washington); Nigel D. Browning (Richland, Washington); Andrey V. Liyu (Richland, Washington) |
| ABSTRACT | Transmission microscopy imaging systems include a mask and/or other modulator situated to encode image beams, e.g., by deflecting the image beam with respect to the mask and/or sensor. The beam is modulated/masked either before or after transmission through a sample to induce a spatially and/or temporally encoded signal by modifying any of the beam/image components including the phase/coherence, intensity, or position of the beam at the sensor. For example, a mask can be placed/translated through the beam so that several masked beams are received by a sensor during a single sensor integration time. Images associated with multiple mask displacements are then used to reconstruct a video sequence using a compressive sensing method. Another example of masked modulation involves a mechanism for phase-retrieval, whereby the beam is modulated by a set of different masks in the image plane and each masked image is recorded in the diffraction plane. |
| FILED | Friday, March 18, 2016 |
| APPL NO | 15/075031 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/20 (20130101) G03F 7/30 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/26 (20130101) H01J 37/222 (20130101) Original (OR) Class H01J 37/244 (20130101) H01J 2237/226 (20130101) H01J 2237/0451 (20130101) H01J 2237/0453 (20130101) H01J 2237/2802 (20130101) H01J 2237/24455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109480 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Seung-Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
| ABSTRACT | Exemplary embodiments provide materials and methods of forming high-quality semiconductor devices using lattice-mismatched materials. In one embodiment, a composite film including one or more substantially-single-particle-thick nanoparticle layers can be deposited over a substrate as a nanoscale selective growth mask for epitaxially growing lattice-mismatched materials over the substrate. |
| FILED | Thursday, May 18, 2017 |
| APPL NO | 15/599376 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/005 (20130101) C30B 23/025 (20130101) C30B 25/04 (20130101) C30B 25/18 (20130101) C30B 25/183 (20130101) C30B 29/40 (20130101) C30B 29/42 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02381 (20130101) H01L 21/02433 (20130101) H01L 21/02455 (20130101) H01L 21/02458 (20130101) H01L 21/02505 (20130101) H01L 21/02513 (20130101) Original (OR) Class H01L 21/02538 (20130101) H01L 21/02546 (20130101) H01L 21/02636 (20130101) H01L 21/02642 (20130101) H01L 21/02647 (20130101) H01L 29/267 (20130101) H01L 29/0665 (20130101) H01L 29/0688 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109760 | Hwang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Gyuweon Hwang (Cambridge, Massachusetts); Donghun Kim (Cambridge, Massachusetts); Jose M. Cordero (Cambridge, Massachusetts); Mark W. B. Wilson (Somerville, Massachusetts); Chia-Hao M. Chuang (Cambridge, Massachusetts); Jeffrey C. Grossman (Brookline, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
| ABSTRACT | The size-dependent band-gap tunability and solution processability of nanocrystals (NCs) make them attractive candidates for optoelectronic applications. One factor that presently limits the device performance of NC thin films is sub-bandgap states, also referred to as trap states. Trap states can be controlled by surface treatment of the nanocrystals. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/095001 |
| ART UNIT | 1673 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) Original (OR) Class H01L 31/036 (20130101) H01L 31/0324 (20130101) H01L 31/0445 (20141201) H01L 31/035218 (20130101) H01L 51/0001 (20130101) H01L 51/42 (20130101) H01L 51/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109845 | Worsley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Marcus A. Worsley (Hayward, California); Theodore F. Baumann (Discovery Bay, California); Juergen Biener (San Leandro, California); Monika M. Biener (San Leandro, California); Yinmin Wang (Tracy, California); Jianchao Ye (Livermore, California); Elijah Tylski (Platte City, Missouri) |
| ABSTRACT | Provided here is a method for making a graphene-supported metal oxide monolith, comprising: providing a graphene aerogel monolith; immersing said graphene aerogel monolith in a solution comprising at least one metal salt to form a mixture; curing said mixture to obtain a gel; optionally, heating said gel to obtain a graphene-supported metal oxide monolith. |
| FILED | Tuesday, November 01, 2016 |
| APPL NO | 15/340875 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) H01G 11/36 (20130101) H01G 11/46 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/0416 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 4/1391 (20130101) H01M 4/1393 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Y02E 60/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109874 | Jahnke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| ASSIGNEE(S) | FUELCELL ENERGY, INC. (Danbury, Connecticut) |
| INVENTOR(S) | Fred C. Jahnke (Rye, New York); Matthew Lambrech (Sherman, Connecticut) |
| ABSTRACT | A multi-stage shift reactor includes a vessel having an inner chamber configured to contain a first shift catalyst, the first shift catalyst configured to receive anode exhaust gas form a fuel cell and to output a first shifted gas, and an outer chamber annularly disposed about the inner chamber and configured to contain a second shift catalyst, the second shift catalyst configured to receive the first shifted gas and output a second shifted gas. The shift reactor further includes a water injection port downstream from the inner chamber and packing between the water injection port and the outer chamber, the packing configured to prevent liquid water from passing therethrough. |
| FILED | Friday, November 04, 2016 |
| APPL NO | 15/344107 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/02 (20130101) B01J 8/0465 (20130101) B01J 19/30 (20130101) B01J 2208/025 (20130101) B01J 2208/00106 (20130101) B01J 2208/00884 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/16 (20130101) C01B 2203/066 (20130101) C01B 2203/0288 (20130101) C01B 2203/0495 (20130101) C01B 2203/0877 (20130101) C01B 2203/1205 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0618 (20130101) Original (OR) Class H01M 8/0662 (20130101) H01M 8/0668 (20130101) H01M 8/04156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109886 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Zhengcheng Zhang (Naperville, Illinois); Wei Weng (Woodridge, Illinois); Nasim Azimi (Bolingbrook, Illinois) |
| ABSTRACT | A lithium-sulfur electrochemical cell includes a cathode including elemental sulfur; an anode including elemental lithium; and an electrolyte including a salt and a non-polar fluorinated ether solvent. Alternatively, a lithium-sulfur electrochemical cell may include an anode; an electrolyte; and a cathode including a polytetrafluoroethylene-coated carbon paper and sulfur. |
| FILED | Tuesday, April 15, 2014 |
| APPL NO | 15/302711 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/663 (20130101) H01M 4/667 (20130101) H01M 4/668 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2004/028 (20130101) H01M 2300/0034 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10110119 | Warmack et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Robert J. Warmack (Knoxville, Tennessee); Charles L. Britton, Jr. (Alcoa, Tennessee); Milton Nance Ericson (Knoxville, Tennessee); John P. Brainard (Albuquerque, New Mexico) |
| ABSTRACT | A multiplier assembly for a power supply and a method of manufacturing the multiplier assembly. The multiplier assembly may be a stack of capacitors and support elements electrically and mechanically coupled together to form a first capacitor string and a second capacitor string. The support elements may electrically and mechanically connect adjacent series capacitors in the first capacitor string. Additionally or alternatively, the support elements may electrically and mechanically connect adjacent series capacitors in the second capacitor string. In one embodiment, the power supply may include drive and feedback circuitry capable of controlling operation of the multiplier assembly. |
| FILED | Friday, December 05, 2014 |
| APPL NO | 15/101642 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/07 (20130101) Original (OR) Class H02M 7/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10110146 | Post et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Richard F Post (Walnut Creek, California); Edward G Cook (Livermore, California) |
| ABSTRACT | A novel motor drive system has been described for use in electrostatic generator/motor systems based on the time variation of capacity of a rotating condenser comprised of segmented rotor and stator elements. It takes advantage of the fact that the motor action of such a system depends only on the rms value of the drive pulses, which therefore can be formed simply by periodically interrupting a high-frequency ac wave train. This new circuitry simplifies the drive system and takes advantage of recent developments of devices used in the art of inversion of dc voltages to high-frequency (tens of kiloHz) ac. |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/503214 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/004 (20130101) H02N 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10110186 | Dimitrovski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Aleksandar D. Dimitrovski (Oak Ridge, Tennessee) |
| ABSTRACT | A magnetic amplifier includes a permeable core having multiple legs. Control windings wound around separate legs are spaced apart and connected in series in an anti-symmetric relation. Harmonic filters are positioned adjacent to the control windings to attenuate even-ordered harmonics generated by alternating load current passing through a portion of the legs. The control windings bias magnetic flux arising from control current flowing through one of the control windings which is substantially equal to the biasing magnetic flux flowing into a second control winding. The flow of the control current through each of the control windings changes the reactance of the permeable core reactor by driving those portions of the permeable core that convey the biasing magnetic flux into saturation. The phasing of the control winding limits a voltage induced in the plurality of control windings caused by a magnetic flux passing around a portion of the permeable core. |
| FILED | Wednesday, May 04, 2016 |
| APPL NO | 15/146671 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/02 (20130101) Amplifiers H03F 9/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10110224 | Nelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Scott D. Nelson (Patterson, California); Steve Hawkins (Livermore, California); Brian R. Poole (Tracy, California) |
| ABSTRACT | Methods, systems, and devices describe triaxial photoconductive switch modules that include a center conductor, an inner conductor, an outer conductor, a high voltage capacitor that is formed between the center conductor and the inner conductor, and a photoconductive switch that is formed between the center conductor and a section of the outer conductor. The disclosed triaxial photoconductive switch modules include low inductance current paths that lead to high current efficiencies. Furthermore, the disclosed triaxial photoconductive switch modules eliminate or reduce parasitic capacitance problems of existing systems. |
| FILED | Monday, March 14, 2016 |
| APPL NO | 15/069838 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) Pulse Technique H03K 17/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10110369 | Grice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Warren P. Grice (Oak Ridge, Tennessee); Raphael C. Pooser (Knoxville, Tennessee); Phani Teja Kuruganti (Knoxville, Tennessee); Philip G. Evans (Konxville, Tennessee); Miljko Bobrek (Knoxville, Tennessee) |
| ABSTRACT | The present disclosure is directed to a system and method of distributing time information to enable synchronization in an authenticated manner via a quantum channel. A source device may transmit a timing signal, T on a communication channel from the source device to a receiver device. The timing signal T may be include a time or times stored in memory or calculated using a previously agreed upon formula. The method may include transmitting a quantum system Q from the source device to the receiver device. The quantum system may be prepared in a randomly chosen state and may be measured by the receiver device in a randomly chosen measurement basis. |
| FILED | Monday, May 01, 2017 |
| APPL NO | 15/583502 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Electric Digital Data Processing G06F 1/12 (20130101) Transmission H04B 10/70 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0075 (20130101) Original (OR) Class H04L 9/0852 (20130101) H04L 63/061 (20130101) H04L 63/1408 (20130101) H04L 63/1475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10111316 | Simakov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Evgenya Simakov (Los Alamos, New Mexico); Dmitry Shchegolkov (Los Alamos, New Mexico) |
| ABSTRACT | A preferred compact particle accelerator can include a cell arranged along a longitudinal axis along which a particle beam is accelerated. The preferred cell can include a first plate disposed substantially orthogonal to the longitudinal axis and a second plate disposed substantially parallel to the first plate. The preferred cell can also include a first set of rods connecting the first plate to the second plate and disposed at a first radius about the longitudinal axis. Preferably, the first set of rods each defines an elliptical cross section. The preferred cell can also include a second set of rods connecting the first plate to the second plate and each disposed at least at a second radius greater than the first radius. Optimized geometry of the elliptical rods and the periodicity of the rods in the lattice provide improved wakefield suppression and allow for significant gains in frequency and output. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/376307 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/2005 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/22 (20130101) H05H 9/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10105186 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Alexis Cheng (Baltimore, Maryland); Emad M. Boctor (Baltimore, Maryland); Xiaoyu Guo (Baltimore, Maryland) |
| ABSTRACT | A virtual rigid body optical tracking system includes a virtual rigid body generator for projecting a virtual rigid body, wherein the virtual rigid body forms a pattern of light on a surface. The virtual rigid body optical tracking system includes an optical detection system for detecting the pattern of light, and a data processing system in communication with the optical detection system. The data processing system is configured to determine a position of the virtual rigid body generator based on the detected pattern of light. |
| FILED | Tuesday, June 09, 2015 |
| APPL NO | 14/734778 |
| ART UNIT | 3737 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/20 (20160201) Original (OR) Class A61B 90/50 (20160201) A61B 2010/045 (20130101) A61B 2017/3413 (20130101) A61B 2018/00577 (20130101) A61B 2034/2055 (20160201) A61B 2034/2057 (20160201) A61B 2034/2065 (20160201) A61B 2090/378 (20160201) A61B 2090/3945 (20160201) A61B 2090/3983 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2025/0166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10105656 | Thomas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sylvia W. Thomas (Orlando, Florida); Norma A. Alcantar (Tampa, Florida); Yanay Pais (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Sylvia W. Thomas (Orlando, Florida); Norma A. Alcantar (Tampa, Florida); Yanay Pais (Tampa, Florida) |
| ABSTRACT | Novel electrospun nanofibers and nanofibrous membranes, methods of manufacturing the same, and methods of using the same are provided. The nanofibers include a cactus mucilage, such as mucilage from Opuntia ficus-indica. An organic polymer can be added to the cactus mucilage before electrospinning. The nanofibrous membranes can be used in water filtration. |
| FILED | Monday, December 19, 2016 |
| APPL NO | 15/383794 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 67/0004 (20130101) B01D 69/02 (20130101) B01D 69/144 (20130101) Original (OR) Class B01D 71/08 (20130101) B01D 71/38 (20130101) B01D 71/52 (20130101) B01D 2253/20 (20130101) B01D 2253/34 (20130101) B01D 2253/202 (20130101) B01D 2253/304 (20130101) B01D 2253/306 (20130101) B01D 2253/308 (20130101) B01D 2253/311 (20130101) B01D 2258/06 (20130101) B01D 2323/39 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/24 (20130101) B01J 20/26 (20130101) B01J 20/261 (20130101) B01J 20/28007 (20130101) B01J 20/28023 (20130101) B01J 20/28038 (20130101) B01J 2220/44 (20130101) B01J 2220/4825 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0004 (20130101) B29C 47/0014 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/286 (20130101) C02F 1/442 (20130101) C02F 2305/08 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) D01D 5/003 (20130101) D01D 5/0092 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/14 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2505/04 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 57/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106514 | Joy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Abraham Joy (Copley, Ohio); John Swanson (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Abraham Joy (Copley, Ohio); John Swanson (Akron, Ohio) |
| ABSTRACT | A thermoresponsive polyester comprising units derived from an amide functional diol compound having a first amide group having a nitrogen atom and a carbonyl group; a second amide group tethered directly or indirectly through an organic group at the carbonyl group of the first amide group; and two organic groups terminated with a hydroxyl group attached to the nitrogen atom of the first amide group. The thermoresponsive polyesters exhibit a lower critical solution temperature at which they undergo a thermally induced reversible hydrophobicity change. This hydrophobicity change may involve the formation of coacervates of the thermoresponsive polyesters which can then coalesce into a precipitated polymer rich phase. |
| FILED | Tuesday, July 28, 2015 |
| APPL NO | 14/811238 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 235/08 (20130101) C07C 235/14 (20130101) C07C 2101/02 (20130101) Heterocyclic Compounds C07D 295/16 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/6856 (20130101) C08G 73/0233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106647 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Jian Yang (State College, Pennsylvania); Jinshan Guo (State College, Pennsylvania) |
| ABSTRACT | In one aspect, compositions are described herein. In some embodiments, a composition described herein comprises the reaction product of (i) citric acid, a citrate, or an ester of citric acid with (ii) a polyol, and (iii) a monomer comprising one or more alkyne moieties and/or azide moieties. The reaction product, in some instances, comprises a polymer. Further, in some cases, a composition described herein comprises a plurality of polymers. In some embodiments, the polymers are selected to be reactive with one another through a click chemistry reaction scheme to form a polymer network. In another aspect, medical implants and medical devices are described herein, the implants and devices comprising a polymer or polymer network described herein. |
| FILED | Thursday, September 04, 2014 |
| APPL NO | 14/916140 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/56 (20130101) A61L 2420/04 (20130101) A61L 2430/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/68 (20130101) C08G 18/73 (20130101) C08G 18/4615 (20130101) C08G 63/12 (20130101) C08G 63/52 (20130101) Original (OR) Class C08G 63/6852 (20130101) C08G 63/6858 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106699 | Gopalan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Padma Gopalan (Madison, Wisconsin); Daniel P. Sweat (Madison, Wisconsin); Myungwoong Kim (Madison, Wisconsin) |
| ABSTRACT | Crosslinkable random copolymers comprising atom transfer radical polymerization (ATRP) initiators and crosslinked copolymer films formed from the copolymers are provided. The random copolymers, which are polymerized from one or more alkyl halide functional inimers and one or more monomers having a crosslinkable functionality, are characterized by pendant ATRP initiating groups and pendant crosslinkable groups. |
| FILED | Thursday, January 30, 2014 |
| APPL NO | 14/168383 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0149 (20130101) B81C 2201/0156 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/16 (20130101) C08F 14/16 (20130101) C08F 20/22 (20130101) C08F 20/32 (20130101) C08F 214/16 (20130101) C08F 220/22 (20130101) C08F 220/32 (20130101) C08F 293/005 (20130101) C08F 2438/01 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2333/14 (20130101) Compositions of Macromolecular Compounds C08L 2312/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/08 (20130101) Original (OR) Class C09D 133/14 (20130101) C09D 133/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106780 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ankur Singh (Smyrna, Georgia); Shalu Suri (Smyrna, Georgia); Todd Christopher McDevitt (Atlanta, Georgia); Hang Lu (Atlanta, Georgia); Andres Jose Garcia (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Ankur Singh (Smyrna, Georgia); Shalu Suri (Smyrna, Georgia); Todd Christopher McDevitt (Atlanta, Georgia); Hang Lu (Atlanta, Georgia); Andres Jose Garcia (Atlanta, Georgia) |
| ABSTRACT | The present invention provides for methods of isolating a stem cell or cell derived therefrom from a mixture of cells, for example, a mixture of adherent cells in culture. Cell isolation is achieved by the application of selective detachment forces. |
| FILED | Thursday, June 21, 2012 |
| APPL NO | 14/128547 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2506/45 (20130101) C12N 2509/10 (20130101) C12N 2527/00 (20130101) C12N 2539/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107735 | Di Carlo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Daniel R. Gossett (Los Angeles, California); Henry T. K. Tse (San Francisco, California); Aram Chung (Los Angeles, California) |
| ABSTRACT | A system for deforming and analyzing particles includes a substrate defining an inlet, and an outlet; a fluidic pathway fluidly coupled to the inlet and the outlet and defining a delivery region upstream of a deformation region configured to deform particles, wherein the fluidic pathway comprises a first branch configured to generate a first flow, and a second branch configured to generate a second flow that opposes the first flow, wherein an intersection of the first flow and the second flow defines the deformation region; a detection module including a sensor configured to generate a morphology dataset characterizing deformation of the particles, and a photodetector configured to generate a fluorescence dataset characterizing fluorescence of the particles; and a processor configured to output an analysis of the plurality of particles based at least in part on the deformation dataset and the fluorescent dataset for the plurality of particles. |
| FILED | Tuesday, December 13, 2016 |
| APPL NO | 15/377659 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) Original (OR) Class G01N 15/1404 (20130101) G01N 15/1434 (20130101) G01N 21/64 (20130101) G01N 2015/1006 (20130101) G01N 2015/1495 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4604 (20130101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107736 | Clare et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Portland State University (Portland, Oregon) |
| ASSIGNEE(S) | Portland State University (Portland, Oregon) |
| INVENTOR(S) | Tami Lasseter Clare (Portland, Oregon); Alice H. England (Portland, Oregon) |
| ABSTRACT | Embodiments of hydrogels for electrochemical sensing, electrodes comprising the hydrogels, and methods of making and using the hydrogels are disclosed. The disclosed hydrogel electrodes comprise a cross-linked poly(acrylic acid-co-2-acrylamido-2-methyl-1-propanesulfonic acid (poly(AA-AMPS)) hydrogel and an electrical contact. |
| FILED | Tuesday, June 10, 2014 |
| APPL NO | 14/896509 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/06 (20130101) C08F 220/58 (20130101) C08F 265/02 (20130101) C08F 265/02 (20130101) C08F 2220/585 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 133/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/02 (20130101) Original (OR) Class G01N 27/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107744 | Pate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); BrightSpec, Inc. (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); BrightSpec, Inc. (Charlottesville, Virginia) |
| INVENTOR(S) | Brooks Hart Pate (Charlottesville, Virginia); Amanda Steber (Mattoon, Illinois); Brent Harris (Charlottesville, Virginia) |
| ABSTRACT | Apparatus and techniques for broadband Fourier transform spectroscopy can include frequency hopping spread-spectrum spectroscopy approaches. For example, an excitation source power can be spread over a specified frequency bandwidth, such as by applying a sequence of short, transform-limited pulses to a sample. Each pulse can include a specified carrier frequency, and a corresponding bandwidth of the individual pulse can be determined by a frequency domain representation when Fourier transformed. A series of short excitation pulses can be used to create an excitation sequence, such as to deliver a specified or desired amount of power to the sample, such as by having the excitation source enabled for a time comparable to a free induction decay (FID) dephasing time. |
| FILED | Tuesday, June 16, 2015 |
| APPL NO | 15/319313 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) Original (OR) Class G01N 2021/3595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107820 | Reilly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James P. Reilly (Bloomington, Indiana); Liangyi Zhang (South San Francisco, California) |
| ASSIGNEE(S) | The Trustees of Indiana University (Indianapolis, Indiana) |
| INVENTOR(S) | James P. Reilly (Bloomington, Indiana); Liangyi Zhang (South San Francisco, California) |
| ABSTRACT | Methods of identifying polypeptides have been developed using a de novo sequencing technique. Methods use photodissociation and low-energy fragmentation and the spectra of peptide ions obtained therefrom, such as obtained by post-source decay (PSD), have been developed. The methods include photodissociation and the spectra therefrom obtainable from treating ions with predetermined wavelengths of radiation in the vacuum ultraviolet range of the electromagnetic spectrum. The confidence of amino acid assignments based on x-type ions is evaluated by observing complementary y-, v- and w-type ions that provide additional constraints to sequence identification. |
| FILED | Friday, December 31, 2010 |
| APPL NO | 13/519255 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6818 (20130101) Original (OR) Class G01N 33/6848 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107835 | Murray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (Baton Rouge, Louisiana) |
| INVENTOR(S) | Kermit King Murray (Baton Rouge, Louisiana); Suman Ghorai (Baton Rouge, Louisiana); Chinthaka Aravinda Seneviratne (Baton Rouge, Louisiana) |
| ABSTRACT | Disclosed are various embodiments for transferring molecules from a surface for mass spectrometry and other sample analysis methods, and the like. A laser is focused onto a tip of an atomic force microscope to remove and capture a quantity of molecules from the surface, so they can be transferred to a mass spectrometer or another instrument for analysis. |
| FILED | Thursday, January 07, 2016 |
| APPL NO | 15/541731 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/16 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/02 (20130101) Original (OR) Class G01Q 60/40 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/40 (20130101) H01J 49/0418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108220 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hao Wang (Madison, Wisconsin); Nam Sung Kim (Middleton, Wisconsin) |
| ABSTRACT | A computer architecture provides both a parallel memory bus and serial memory bus between a processor system and memory. Latency-tolerant memory access requests are steered to the serial memory bus which operates to increase the available memory bus bandwidth on the parallel memory. The invention also provides integrated circuit computer memory suitable for this application. |
| FILED | Thursday, May 01, 2014 |
| APPL NO | 14/267190 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/10 (20130101) Original (OR) Class G06F 3/0635 (20130101) G06F 13/16 (20130101) G06F 13/40 (20130101) G06F 13/42 (20130101) G06F 13/161 (20130101) G06F 13/1663 (20130101) G06F 13/1684 (20130101) G06F 13/4018 (20130101) G06F 13/4234 (20130101) G06F 13/4243 (20130101) G06F 2213/0038 (20130101) G06F 2213/0042 (20130101) G06F 2213/0064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108288 | Peshkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael A. Peshkin (Evanston, Illinois); J. Edward Colgate (Evanston, Illinois) |
| ABSTRACT | A method of moving a plurality of appendages of an operator in contact with a touch surface including the steps of measuring a plurality of locations when the touch surface is touched by the plurality of appendages, moving the touch surface in a swirling motion by one or more actuators coupled with the touch surface, controlling a voltage on each of a plurality of electrodes disposed below the touch surface, controlling an electrostatic normal force acting on each of the appendages by adjusting the voltage applied to each of the plurality of appendages by each electrode lying beneath the appendage, synchronizing the electrostatic normal force generated by the voltage applied to each of the plurality of appendages with the swirling motion by basing a frequency of the swirling motion on the frequency of application of the electrostatic normal force. |
| FILED | Friday, October 20, 2017 |
| APPL NO | 15/789495 |
| ART UNIT | 2697 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/016 (20130101) G06F 3/041 (20130101) G06F 3/044 (20130101) G06F 3/045 (20130101) G06F 3/046 (20130101) G06F 3/0412 (20130101) G06F 3/0414 (20130101) Original (OR) Class G06F 3/0416 (20130101) G06F 2203/04101 (20130101) G06F 2203/04105 (20130101) G06F 2203/04112 (20130101) G06F 2203/04113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108348 | Yang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HGST Netherlands B.V. (Amsterdam, Netherlands) |
| ASSIGNEE(S) | Western Digital Technologies, Inc. (San Jose, California) |
| INVENTOR(S) | Qing Yang (Saunderstwon, Rhode Island) |
| ABSTRACT | A data storage architecture is composed of an array of a flash memory solid state disk and a hard disk drive or any nonvolatile random access storage that are intelligently coupled by an intelligent processing unit such as a multi-core graphic processing unit. The solid state disk stores seldom-changed and mostly read reference data blocks while the hard disk drive stores compressed deltas between currently accessed I/O blocks and their corresponding reference blocks in the solid state disk so that random writes are not performed on the solid state disk during online I/O operations. The solid state disk and hard disk drive are controlled by the intelligent processing unit, which carries out high speed computations including similarity detection and delta compression/decompression. The architecture exploits the fast read performance of solid state disks and the high speed computation of graphic processing units to replace mechanical operations on hard disk drives while avoiding slow and wearing solid state drive writes. |
| FILED | Wednesday, October 14, 2015 |
| APPL NO | 14/882741 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/068 (20130101) G06F 3/0611 (20130101) Original (OR) Class G06F 3/0613 (20130101) G06F 3/0616 (20130101) G06F 3/0659 (20130101) G06F 3/0685 (20130101) G06F 12/0868 (20130101) G06F 2212/214 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/13 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109802 | Siraj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Noureen Siraj (Baton Rouge, Louisiana); Isiah Manuel Warner (Baton Rouge, Louisiana); Thenahandi Prasanthi Deepthika De Silva (Baton Rouge, Louisiana) |
| ABSTRACT | Various examples are provided for carbazole-based GUMBOS (group of uniform materials based on organic salts), and its application in organic light emitting diodes (OLEDs). In one example, a composition includes a solid phase carbazole-based GUMBOS (group of uniform materials based on organic salts) comprising a counterion such as, e.g., trifluoromethanesulfonate ([Otf]), bis-(trifluoromethanesulfonyl)imide ([NTf2]), bis-(pentafluoroethylsulfonyl)imide ([BETI]), tetrafluoroborate (BF4), hexafluorophosphate (PF6), and/or thiocyanate (SCN). The carbazole-based GUMBOS can include carbazoleimidazole-based GUMBOS or 3,6-diBDC carbazolium-based GUMBOS. In another example, a method includes preparing a biphasic solution; separating a layer of DCM from the biphasic solution after stirring; washing the DCM with water to remove byproducts; and evaporating the DCM to form a solid phase carbazoleimidazole-based GUMBOS. Preparing the biphasic solution can include carbazoleimidazolium iodide (CM) dissolved in dichloromethane (DCM) and a dissolved salt including a sodium salt or a lithium salt. |
| FILED | Tuesday, January 05, 2016 |
| APPL NO | 15/541524 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 303/30 (20130101) C07C 303/40 (20130101) C07C 309/66 (20130101) C07C 311/48 (20130101) Heterocyclic Compounds C07D 403/04 (20130101) C07D 403/14 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0025 (20130101) H01L 51/56 (20130101) H01L 51/0067 (20130101) H01L 51/0072 (20130101) Original (OR) Class H01L 51/5032 (20130101) H01L 51/5072 (20130101) H01L 51/5206 (20130101) H01L 51/5221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109976 | Wise et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Frank W. Wise (Ithaca, New York); Erin Stranford Lamb (Ithaca, New York); Logan Wright (Ithaca, New York) |
| ABSTRACT | Methods, systems, and devices are disclosed for divided-pulse lasers. In one aspect, a pulsed laser is provided to include a laser cavity including an optical amplifier and a plurality of optical dividing elements and configured to direct a laser pulse of linearly polarized light into the plurality of optical dividing elements to divide the light of the laser pulse into a sequence of divided pulses each having a pulse energy being a portion of the energy of the laser pulse before entry of the optical dividing elements, to subsequently direct the divided pulses into the optical amplifier to produce amplified divided pulses. The laser cavity is configured to direct the amplified divided pulses back into the plurality of optical dividing elements for a second time in an opposite direction to recombine the amplified divided pulses into a single laser pulse with greater pulse energy as an output pulse of the laser cavity. |
| FILED | Wednesday, January 21, 2015 |
| APPL NO | 15/113349 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/08 (20130101) H01S 3/081 (20130101) H01S 3/0826 (20130101) H01S 3/1118 (20130101) H01S 3/1618 (20130101) H01S 3/2333 (20130101) H01S 3/06712 (20130101) Original (OR) Class H01S 3/06791 (20130101) H01S 3/08054 (20130101) H01S 3/10046 (20130101) H01S 2301/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 10105243 | Hansen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Andrew H. Hansen (Apple Valley, Minnesota); Eric A. Nickel (Brooklyn Park, Minnesota) |
| ABSTRACT | An ankle-foot prosthesis includes a foot plate, an ankle frame attached to the foot plate, a yoke pivotally connected to the ankle frame and including a member for attaching to a leg, a damper having a first end connected to the yoke and a second end connected to the ankle frame, and a control mechanism for switching the damper between low and high settings. |
| FILED | Tuesday, November 22, 2016 |
| APPL NO | 15/359242 |
| ART UNIT | 3738 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/6607 (20130101) Original (OR) Class A61F 2002/745 (20130101) A61F 2002/748 (20130101) A61F 2002/5006 (20130101) A61F 2002/6642 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106773 | Cheung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Herman S. Cheung (Miami, Florida); Daniel Pelaez (Miami, Florida); C-Y Charles Huang (Miami, Florida) |
| ABSTRACT | The present invention relates to methods of isolating a substantially homogeneous population of pluripotent stem cells from adult neural crest tissue (e.g., periodontal ligament) as well as pharmaceutical compositions comprising such isolated pluripotent stem cells. Methods of inducing the isolated pluripotent stem cells into specific cell lineages, such as neurogenic and retinogenic lineages, are also described. The isolated pluripotent stem cells find use in various regenerative medicine applications and the treatment of degenerative diseases. |
| FILED | Friday, March 01, 2013 |
| APPL NO | 14/382287 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 35/545 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) C12N 5/0607 (20130101) C12N 5/0618 (20130101) C12N 5/0623 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2506/03 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107795 | Kishore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Bellamkonda K. Kishore (Washington, District of Columbia); Yue Zhang (Washington, District of Columbia); Carolyn M. Ecelbarger (Washington, District of Columbia) |
| ABSTRACT | Blunting the activity of the P2Y2 receptor results in a resistance to diet-induced obesity, an increased metabolic rate, and a better glucose tolerance. Compounds that inhibit the puringeric P2Y2 receptor are useful for treating disorders associated with diabetes, treating obesity, and increasing metabolism (e.g., fatty acid metabolism). |
| FILED | Friday, October 25, 2013 |
| APPL NO | 14/438854 |
| ART UNIT | 1674 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2207/25 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0362 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 47/26 (20130101) Peptides C07K 16/28 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) Enzymes C12Y 301/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10105909 | Feldman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jay D. Feldman (Sunnyvale, California); Curt G. Wilkinson (Fleetwood, Pennsylvania); Kenneth J. Mercer (San Diego, California); Ethiraj Venkatapathy (Los Altos, California) |
| ABSTRACT | A system for fabricating an ablative, 3D fiber-woven thermal protection material, with porosity 0.5-15 percent, reduced thermal conductivity, very low thermal recession, high glass transition temperature, high frontface-backface temperature difference, relatively high mass density, and significant compression strength and tensile strength. |
| FILED | Wednesday, March 23, 2016 |
| APPL NO | 15/078617 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/24 (20130101) Original (OR) Class B29C 70/443 (20130101) B29C 71/02 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2061/04 (20130101) B29K 2079/08 (20130101) B29K 2309/08 (20130101) B29K 2995/0015 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10106214 | Karras et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Jaakko T. Karras (Pasadena, California); Christine Fuller (Pasadena, California); Kalind C. Carpenter (Pasadena, California); Alessandro Buscicchio (Pasadena, California); Carolyn E. Parcheta (Pasadena, California) |
| ABSTRACT | A repeatably reconfigurable robot, comprising at least two printed circuit board (PCB) rigid sections, at least one PCB flexible section coupled to the at least two PCB rigid sections, at least one wheel, hybrid wheel propeller, wheel and propeller, or hybrid wheel screw propeller rotatably coupled to at least one of the at least two PCB rigid sections and at least one actuator coupled to the at least two PCB rigid sections, wherein the at least one actuator folds and unfolds the repeatably reconfigurable robot. |
| FILED | Wednesday, September 21, 2016 |
| APPL NO | 15/272239 |
| ART UNIT | 3611 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Motor Vehicles; Trailers B62D 57/02 (20130101) Original (OR) Class Aeroplanes; Helicopters B64C 27/08 (20130101) B64C 39/024 (20130101) B64C 2201/024 (20130101) B64C 2201/042 (20130101) B64C 2201/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107139 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael G. Jones (Newport News, Virginia); Joseph E. Grady (Avon, Ohio); James D. Kiser (Hinckley, Ohio); Christopher Miller (Rocky River, Ohio); James D. Heidmann (Solon, Ohio) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Michael G. Jones (Newport News, Virginia); Joseph E. Grady (Avon, Ohio); James D. Kiser (Hinckley, Ohio); Christopher Miller (Rocky River, Ohio); James D. Heidmann (Solon, Ohio) |
| ABSTRACT | An improved acoustic liner for turbine engines is disclosed. The acoustic liner may include a straight cell section including a plurality of cells with straight chambers. The acoustic liner may also include a bent cell section including one or more cells that are bent to extend chamber length without increasing the overall height of the acoustic liner by the entire chamber length. In some cases, holes are placed between cell chambers in addition to bending the cells, or instead of bending the cells. |
| FILED | Monday, October 24, 2016 |
| APPL NO | 15/332524 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/04 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/30 (20130101) F05D 2260/96 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/161 (20130101) G10K 11/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10107768 | Brady et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | David Jones Brady (Durham, North Carolina); Joel Alter Greenberg (Durham, North Carolina); Shuo Pang (Durham, North Carolina); Kenneth Patrick MacCabe (Raleigh, North Carolina) |
| ABSTRACT | An imaging system operative for providing a volumetric molecular image of an object is disclosed. The imaging system interrogates the object with structured x-ray radiation while continuous relative motion between the object and source is induced during a measurement period. As the radiation passes through the object, the radiation scatters based on the molecular composition within the object, and the scattering changes as a function of time due to the relative motion between the source and object. Coherent scatter radiation is detected and processed to reconstruct an estimate of the three-dimensional molecular structure of the object using a reconstruction algorithm, such as maximum likelihood estimation. |
| FILED | Wednesday, August 13, 2014 |
| APPL NO | 14/912014 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/207 (20130101) Original (OR) Class G01N 23/20008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10109221 | Yazdi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Evigia Systems, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Navid Yazdi (Ann Arbor, Michigan); William Kwolek (Manchester, Michigan) |
| ABSTRACT | A tamper-proof bolt-seal incorporating a unique identification tamper detection sensor that cannot be restored or duplicated after the bolt. The sensor employs a resistive sensor wire embedded in the bolt. The resistive sensor wire has a randomized length to enable a unique resistive value for that sensor. The resistive value of the sensor is combined with an electronic identification code to create the unique seal identification for the tamper detection sensor, therefore giving the bolt a seal identification that is unique and that cannot be restored or duplicated. |
| FILED | Tuesday, October 11, 2016 |
| APPL NO | 15/291029 |
| ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Locks; Accessories Therefor; Handcuffs E05B 39/005 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/06 (20130101) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 3/0317 (20130101) G09F 3/0329 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10105867 | Dooley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Forest Concepts, LLC (Auburn, Washington) |
| ASSIGNEE(S) | Forest Concepts, LLC (Auburn, Washington) |
| INVENTOR(S) | James H. Dooley (Federal Way, Washington); David N. Lanning (Federal Way, Washington) |
| ABSTRACT | Comminution process of wood chips to produce wood particles, by feeding wood chips in a direction of travel substantially normal to grain through a counter rotating pair of intermeshing arrays of cutting discs arrayed axially perpendicular to the direction of wood chip travel, wherein the cutting discs have a uniform thickness (Td), to produce wood particles characterized by a length dimension (L) substantially equal to the Td and aligned substantially parallel to grain, a width dimension (W) normal to L and aligned cross grain, and a height dimension (H) aligned normal to W and L, wherein the W×H dimensions define a pair of substantially parallel end surfaces with crosscut fibers. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 15/444983 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Removing Bark or Vestiges of Branches; Splitting Wood; Manufacture of Veneer, Wooden Sticks, Wood Shavings, Wood Fibres or Wood Powder B27L 11/00 (20130101) Original (OR) Class B27L 11/02 (20130101) Fibrous Raw Materials or Their Mechanical Treatment D21B 1/061 (20130101) D21B 1/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10107744 | Pate et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); BrightSpec, Inc. (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); BrightSpec, Inc. (Charlottesville, Virginia) |
| INVENTOR(S) | Brooks Hart Pate (Charlottesville, Virginia); Amanda Steber (Mattoon, Illinois); Brent Harris (Charlottesville, Virginia) |
| ABSTRACT | Apparatus and techniques for broadband Fourier transform spectroscopy can include frequency hopping spread-spectrum spectroscopy approaches. For example, an excitation source power can be spread over a specified frequency bandwidth, such as by applying a sequence of short, transform-limited pulses to a sample. Each pulse can include a specified carrier frequency, and a corresponding bandwidth of the individual pulse can be determined by a frequency domain representation when Fourier transformed. A series of short excitation pulses can be used to create an excitation sequence, such as to deliver a specified or desired amount of power to the sample, such as by having the excitation source enabled for a time comparable to a free induction decay (FID) dephasing time. |
| FILED | Tuesday, June 16, 2015 |
| APPL NO | 15/319313 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) Original (OR) Class G01N 2021/3595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10105409 | Arvik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sonomaceuticals, LLC (Santa Rosa, California); The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | SONOMACEUTICALS, LLC (Santa Rosa, California); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| INVENTOR(S) | Torey James Arvik (Santa Rosa, California); Rebecca Susan Lipson (Santa Rosa, California); Wallace H. Yokoyama (Albany, California) |
| ABSTRACT | The present disclosure relates to health benefits of Chardonnay seed products. |
| FILED | Monday, April 29, 2013 |
| APPL NO | 14/398093 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 36/87 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10109983 | Liang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Di Liang (Palo Alto, California); Geza Kurczveil (Palo Alto, California); Raymond G. Beausoleil (Palo Alto, California); Marco Fiorentino (Palo Alto, California) |
| ABSTRACT | An example method of manufacturing a semiconductor device. A first wafer may be provided that includes a first layer that contains quantum dots. A second wafer may be provided that includes a buried dielectric layer and a second layer on the buried dielectric layer. An interface layer may be formed on at least one of the first layer and the second layer, where the interface layer may be an insulator, a transparent electrical conductor, or a polymer. The first wafer may be bonded to the second wafer by way of the interface layer. |
| FILED | Thursday, April 28, 2016 |
| APPL NO | 15/140588 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0637 (20130101) H01S 3/2375 (20130101) H01S 5/021 (20130101) H01S 5/0216 (20130101) H01S 5/343 (20130101) Original (OR) Class H01S 5/347 (20130101) H01S 5/3211 (20130101) H01S 5/3412 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10107895 | Cho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Seal Beach, California) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Kwang M. Cho (Los Angeles, California); Kenneth W. Conte (Los Angeles, California) |
| ABSTRACT | A Radar Calibration Processor (“RCP”) for calibrating the amplitude of a stepped-chirp signal utilized by a synthetic aperture radar (“SAR”) is disclosed. The RCP includes a periodic amplitude error (“PAE”) calibrator, first non-periodic amplitude error (“NPAE”) calibrator in signal communication with the PAE calibrator, and a second NPAE calibrator in signal communication with the first NPAE calibrator. |
| FILED | Friday, September 19, 2014 |
| APPL NO | 14/491291 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4004 (20130101) Original (OR) Class G01S 13/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10108604 | McGregor Olney |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew McGregor Olney (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew McGregor Olney (Memphis, Tennessee) |
| ABSTRACT | A system for processing text files to extract and create conceptual graphs. The system determines key terms, prescribes a set of edge relations (i.e., defines edge categories), and the extracts conceptual graphs from source documents, including raw text, using these representations together with a semantic parser, followed by post processing. The conceptual graphs can then be used for a variety of purposes, including the creation of questions in an automated tutor system. |
| FILED | Friday, November 19, 2010 |
| APPL NO | 12/950560 |
| ART UNIT | 2153 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/2785 (20130101) Original (OR) Class G06F 17/30684 (20130101) G06F 17/30734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 23, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20181023.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page