FedInvent™ Patents

Patent Details for Tuesday, November 06, 2018

This page was updated on Monday, March 27, 2023 at 05:39 AM GMT

Department of Health and Human Services (HHS)

10117610 — Method for spectrophotometric blood oxygenation monitoring

US 10117610	Benni
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	CAS Medical Systems, Inc. (Branford, Connecticut)
ASSIGNEE(S)	CAS Medical Systems, Inc. (Branford, Connecticut)
INVENTOR(S)	Paul B. Benni (Acton, Massachusetts)
ABSTRACT	According to the present invention, a method and apparatus for non-invasively determining the blood oxygen saturation level within a subject's tissue is provided. The method comprises the steps of: a) providing a spectrophotometric sensor operable to transmit light into the subject's tissue, and to sense the light; b) detecting light after passage through the subject's tissue using the sensor, and producing initial signal data from the light sensed; c) calibrating the sensor to that particular subject using the initial signal data, thereby accounting for the specific physical characteristics of the particular subject's tissue being sensed; and d) using the calibrated sensor to determine the blood oxygen parameter value within the subject's tissue.
FILED	Monday, October 03, 2016
APPL NO	15/283883
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0205 (20130101) A61B 5/0261 (20130101) A61B 5/1495 (20130101) A61B 5/6814 (20130101) A61B 5/14546 (20130101) A61B 5/14551 (20130101) Original (OR) Class A61B 5/14552 (20130101) A61B 5/14553 (20130101)
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10117738 — Atraumatic tip geometry for indwelling devices

US 10117738	Demehri et al.
FUNDED BY	Department of Health and Human Services (HHS) Food and Drug Administration (FDA)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Farokh R. Demehri (Ann Arbor, Michigan); Daniel H. Teitelbaum (Ann Arbor, Michigan); Jonathan E. Luntz (Ann Arbor, Michigan); Brent Utter (Easton, Pennsylvania); Diann Erbschloe Brei (Milford, Michigan); Jennifer Freeman (Cambridge, Massachusetts)
ABSTRACT	An indwelling device for insertion in a biological tubular structure comprising an elongated device having a body and opposing ends. The body has a bending stiffness transverse to a longitudinal axis that is greater than a stiffness of the biological tubular structure. An atraumatic tip member, having a proximal end and a distal end, extends from the end of the elongated device. The proximal end has a first bending stiffness transverse to a longitudinal axis and the distal end has a second bending stiffness transverse to the longitudinal axis, wherein the second bending stiffness being less than the first bending stiffness.
FILED	Monday, January 25, 2016
APPL NO	15/005218
ART UNIT	3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/02 (20130101) A61B 17/12045 (20130101) A61B 2017/00557 (20130101) A61B 2017/00818 (20130101) A61B 2017/12127 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/04 (20130101) Original (OR) Class A61F 2002/045 (20130101) A61F 2250/001 (20130101) A61F 2250/0018 (20130101) A61F 2250/0029 (20130101) A61F 2250/0059 (20130101) A61F 2250/0069 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 29/02 (20130101)
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10117840 — Sulfur(VI) fluoride compounds and methods for the preparation thereof

US 10117840	Dong et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Jiajia Dong (Shanghai, China PRC); K. Barry Sharpless (La Jolla, California); Jeffery W. Kelly (La Jolla, California); Wentao Chen (Walnut Creek, California)
ABSTRACT	This application describes a compound represented by Formula (I): (I) wherein: Y is a biologically active organic core group comprising one or more of an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group, to which Z is covalently bonded; n is 1, 2, 3, 4 or 5; m is 1 or 2; Z is O, NR, or N; X¹is a covalent bond or —CH₂CH₂—, X²is O or NR; and R comprises H or a substituted or unsubstituted group selected from an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group. Methods of preparing the compounds, methods of using the compounds, and pharmaceutical compositions comprising the compounds are described as well.
FILED	Friday, June 05, 2015
APPL NO	15/316742
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 31/14 (20130101) A61K 31/40 (20130101) A61K 31/47 (20130101) A61K 31/53 (20130101) A61K 31/56 (20130101) A61K 31/65 (20130101) A61K 31/70 (20130101) A61K 31/136 (20130101) A61K 31/197 (20130101) A61K 31/198 (20130101) A61K 31/397 (20130101) A61K 31/407 (20130101) A61K 31/439 (20130101) A61K 31/473 (20130101) A61K 31/485 (20130101) A61K 31/505 (20130101) A61K 31/515 (20130101) A61K 31/655 (20130101) A61K 31/4045 (20130101) A61K 31/4168 (20130101) A61K 31/4245 (20130101) A61K 31/4353 (20130101) A61K 31/4709 (20130101) A61K 31/4745 (20130101) A61K 31/5513 (20130101) A61K 31/7048 (20130101) A61K 38/31 (20130101) A61K 47/54 (20170801) A61K 47/48023 (20130101) A61K 51/0497 (20130101) Acyclic or Carbocyclic Compounds C07C 305/26 (20130101) C07C 2601/14 (20170501) C07C 2603/18 (20170501) Heterocyclic Compounds C07D 277/82 (20130101) C07D 295/26 (20130101) C07D 295/088 (20130101) C07D 295/185 (20130101) Peptides C07K 1/02 (20130101) C07K 1/1136 (20130101) C07K 2/00 (20130101)
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10117845 — Retinal derivatives and methods for the use thereof for the treatment of visual disorders

US 10117845	Palczewski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Krzysztof Palczewski (Bay Village, Ohio); Matthew Batten (Seattle, Washington)
ABSTRACT	Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
FILED	Tuesday, July 19, 2016
APPL NO	15/214330
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 9/0053 (20130101) A61K 31/22 (20130101) A61K 31/215 (20130101) A61K 31/225 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/09 (20130101) Acyclic or Carbocyclic Compounds C07C 403/10 (20130101) C07C 403/12 (20130101) C07C 403/14 (20130101) C07C 403/20 (20130101) C07C 2601/10 (20170501) C07C 2601/16 (20170501)
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10117866 — Promoting axon regeneration in the adult CNS through control of protein translation

US 10117866	He et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S)	CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S)	Zhigang He (Wellesley, Massachusetts); Kevin Park (Boston, Massachusetts); Kai Liu (Jamesburg, New Jersey); Yang Hu (Brookline, Massachusetts)
ABSTRACT	Survival of, or axon regeneration in a lesioned mature central nervous system (CNS) neuron is promoted by (a) contacting the neuron with a therapeutically effective amount of an exogenous activator of protein translation; and (b) detecting the resultant promotion of the survival of, or axon regeneration in the neuron.
FILED	Thursday, April 03, 2014
APPL NO	14/244065
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/28 (20130101) A61K 31/555 (20130101) A61K 31/4375 (20130101) A61K 31/4745 (20130101) Original (OR) Class
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10117871 — 3-hydroxypyrimidine-2,4-dione-5-carboxamides as potent inhibitors of HIV

US 10117871	Wang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S)	Zhengqiang Wang (Eden Prairie, Minnesota)
ABSTRACT	Various embodiments described herein are directed to compounds of formula (I), (II), (III) or (IV) for use as potent inhibitors of HIV integrase and for treatment of patients afflicted with AIDS. A major challenge of human immunodeficiency virus (HIV) chemotherapy continues to be the inevitable selection of resistance by the virus towards known drug regimens. Treating resistant HIV strains calls for novel antivirals with unique structural cores. Some embodiments are directed to compounds featuring a 3-hydroxypyrimidine-2,4-dione-5-carboxamide core that consistently confers low nanomolar potencies against HIV-1 in cell culture. Biochemical testing and molecular modeling results corroborate an antiviral mechanism of action of inhibiting integrase strand transfer (INST). Preliminary testing against raltegravir-resistant HIVs showed marginal cross resistance, suggesting that the chemotypes of the various embodiments described herein could fit an inhibitory profile of second generation INSTIs.
FILED	Thursday, March 03, 2016
APPL NO	15/553508
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/03 (20130101) A61K 31/513 (20130101) Original (OR) Class Heterocyclic Compounds C07D 239/557 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16063 (20130101)
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10117897 — Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes

US 10117897	Sadelain et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)	MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S)	Michel Sadelain (New York, New York); Matthias Stephan (Boston, Massachusetts)
ABSTRACT	The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen-recognizing receptor and a co-stimulatory ligand and methods of use therefore for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired.
FILED	Tuesday, June 09, 2015
APPL NO	14/734969
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/217 (20130101) A61K 38/2013 (20130101) A61K 39/0011 (20130101) A61K 45/06 (20130101) A61K 2035/122 (20130101) A61K 2035/124 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 7/00 (20130101) C12N 15/85 (20130101) C12N 2501/25 (20130101) C12N 2501/51 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) C12N 2799/04 (20130101)
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10117907 — Glycosylated PACAP/VIP analogues with enhanced CNS penetration for treatment of neurodegenerative diseases

US 10117907	Polt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of the University of Arizona, a body corporate (Tucson, Arizona)
INVENTOR(S)	Robin Polt (Tucson, Arizona); Torsten A E Falk (Tucson, Arizona)
ABSTRACT	A glycosylated pleiotropic peptide pituitary adenylate cyclase-activating polypeptide (PACAP) which can both agonize PAC₁receptors, causing neuroprotective effects, and antagonize VPAC receptors, causing anti-inflammation in several models of acute neuronal damage and neurodegenerative diseases, including ALS, PD, migraines, and certain forms of dementia, is described. Also described is a method of relieving symptoms of ALS, PD, migraines, and certain forms of dementia, comprising administering to a subject in need thereof an effective amount of a glycosylated PACAP.
FILED	Tuesday, February 16, 2016
APPL NO	15/044924
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class A61K 38/2278 (20130101) Peptides C07K 2317/21 (20130101) C07K 2317/41 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/2814 (20130101) G01N 2800/2821 (20130101)
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10117913 — Antigens of Pneumocystis murina and uses thereof

US 10117913	Shellito et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana); THE UNIVERSITY OF NEW ORLEANS (New Orleans, Louisiana)
ASSIGNEE(S)	BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (Baton Rouge, Louisiana); THE UNIVERSITY OF NEW ORLEANS (New Orleans, Louisiana)
INVENTOR(S)	Judd E. Shellito (New Orleans, Louisiana); Alistair John Ramsay (New Orleans, Louisiana); David A. Welsh (New Orleans, Louisiana); Sanbao Ruan (New Orleans, Louisiana); Yang Cai (New Orleans, Louisiana)
ABSTRACT	A surface protein of the murine fungal pathogen Pneumocystis murina can be used to generate an immune response in a recipient animal or human that provides prophylactic protection and an anti-fungal activity in subjects already infected with a Pneumocystis species. Further, the disclosure provides novel polypeptides or peptides derived from the P. murina surface protein Surface Peptidase 1 (SPD-1) that are useful, alone or in combination with the SPD-1 polypeptide, in compositions and methods for the generation of an anti-Pneumocystis immune reaction by a recipient subject. The compositions and methods of the disclosure provide advantageous alternatives to available immunogenic determinants for the treatment or prevention of fungal pneumonia.
FILED	Monday, May 04, 2015
APPL NO	15/305190
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/0002 (20130101) Original (OR) Class A61K 2039/55566 (20130101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/48 (20130101)
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10117915 — Modulation of yeast-based immunotherapy products and responses

US 10117915	Bellgrau et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate (Denver, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Donald Bellgrau (Highlands Ranch, Colorado); Beth Tamburini (Lakewood, Colorado)
ABSTRACT	Disclosed are methods to modulate yeast-based immunotherapy products and the immune responses, prophylactic responses, and/or therapeutic responses elicited by such products. Also disclosed are modified yeast-based immunotherapy products, kits and compositions.
FILED	Monday, November 10, 2014
APPL NO	14/536903
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 36/06 (20130101) A61K 36/064 (20130101) A61K 39/0005 (20130101) Original (OR) Class A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 2039/57 (20130101) A61K 2039/505 (20130101) A61K 2039/523 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 2800/52 (20130101)
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10117919 — Methods and materials for generating CD8⁺T cells having the ability to recognize cancer cells expressing a HER2/neu polypeptide

US 10117919	Knutson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	Keith L. Knutson (Jacksonville, Florida); Andrea M. Henle (Cambridge, Massachusetts)
ABSTRACT	This document provides methods and materials for generating CD8⁻ T cells having the ability to recognize cancer cells expressing a HER2/neu polypeptide. For example, methods and materials for using a polypeptide consisting of an SLAFLPESFD amino acid sequence in vivo or in vitro to generate CD8⁺ T cells having the ability to recognize and lyse cancer cells expressing a HER2/neu polypeptide are provided.
FILED	Monday, November 13, 2017
APPL NO	15/810924
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/193 (20130101) A61K 38/193 (20130101) A61K 38/208 (20130101) A61K 38/208 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/55566 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/71 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101)
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10117922 — Dengue virus specific multiple HLA binding T cell epitopes for the use of universal vaccine development

US 10117922	Philip
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Emergex Vaccines Holding Ltd. (Abingdon, United Kingdom)
ASSIGNEE(S)	Emergex Vaccines Holding Ltd. (Abingdon, Oxford, United Kingdom)
INVENTOR(S)	Ramila Philip (Ivyland, Pennsylvania)
ABSTRACT	Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) are significant global public health problems and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Live attenuated and subunit vaccine candidates, which are under clinical evaluation, induce primarily an antibody response to the virus and minimal cross-reactive T cell responses. Currently, there are no available tools to assess protective T cell responses during infection or post vaccination. Herein, we report novel, naturally processed and presented MHC class I restricted epitopes, a subset of which binds to and activates T cells in both an HLA-A2 and HLA-A24 restricted manner. We show that epitope specific T cells can be activated in vivo in transgenic mice and in vitro in seropositive and seronegative individuals and that these T cells are functional, recognizing peptide pulsed and dengue virus infected cells in a pro-inflammatory and cytotoxic manner. These epitopes have potential as new informational and diagnostic tools to characterize T cell immunity in Dengue virus (DV) infection, and may serve as a universal vaccine candidate complementary to current vaccines in trial.
FILED	Monday, May 11, 2015
APPL NO	15/310542
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/572 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24122 (20130101) C12N 2770/24134 (20130101)
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10117924 — Chimeric dengue virus E glycoproteins comprising mutant domain I and domain II hinge regions

US 10117924	de Silva et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Aravinda M. de Silva (Chapel Hill, North Carolina); A. Ruklanthi de Alwis (Dehiwala, Sri Lanka); Wahala M. P. B. Wahala (Carmel, Indiana); Ralph S. Baric (Haw River, North Carolina); William B. Messer (Portland, Oregon); James E. Crowe, Jr. (Nashville, Tennessee); Scott A. Smith (Nashville, Tennessee)
ABSTRACT	The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce a dengue virus E glycoprotein domain I and domain II hinge region from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
FILED	Friday, October 13, 2017
APPL NO	15/783675
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/70 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24023 (20130101) C12N 2770/24122 (20130101) C12N 2770/24123 (20130101) C12N 2770/24134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/185 (20130101) G01N 2469/20 (20130101) Technologies for Adaptation to Climate Change Y02A 50/39 (20180101) Y02A 50/386 (20180101) Y02A 50/388 (20180101) Y02A 50/394 (20180101)
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10117928 — Annexin II compositions

US 10117928	Ohlfest et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S)	John R. Ohlfest (Minneapolis, Minnesota); Michael R. Olin (New Brighton, Minnesota)
ABSTRACT	The present invention provides compositions and methods that involve the 36 kDa annexin II monomer, which has been identified as having immunostimulatory properties. Accordingly, in one aspect, the invention provides compositions that include at least one 36 kDa annexin II monomer or an immunomodulatory fragment thereof. In another aspect, the invention provides methods that include administering to a subject a composition that includes at least one 36 kDa annexin II monomer or an immunomodulatory fragment thereof. In another aspect, the invention provides methods that induce an in situ increase in the 36 kDa annexin II monomer by administering to a subject an amount of composition effective to induce localized hypoxia sufficient to cause a localized increase in annexin II.
FILED	Tuesday, December 27, 2016
APPL NO	15/390948
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) A61K 38/1709 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 51/087 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/00 (20130101)
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10117941 — Lipids and compositions for the delivery of therapeutics

US 10117941	Manoharan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Arbutus Biopharma Corporation (Burnaby, Canada)
ASSIGNEE(S)	Arbutus Biopharma Corporation (Burnaby, British Columbia, Canada)
INVENTOR(S)	Muthiah Manoharan (Cambridge, Massachusetts); Kallanthottathil G. Rajeev (Cambridge, Massachusetts); Muthusamy Jayaraman (Cambridge, Massachusetts); David Butler (Medford, Massachusetts); Jayaprakash K. Nair (Cambridge, Massachusetts); Martin Maier (Cambridge, Massachusetts); Laxman Eltepu (Cambridge, Massachusetts)
ABSTRACT	The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure wherein R₁and R₂are each independently for each occurrence optionally substituted C₁₀-C₃₀alkyl, optionally substituted C₁₀-C₃₀alkenyl, optionally substituted C₁₀-C₃₀alkynyl, optionally substituted C₁₀-C₃₀acyl, or -linker-ligand; R₃is H, optionally substituted C₁-C₁₀alkyl, optionally substituted C₂-C₁₀alkenyl, optionally substituted C₂-C₁₀alkynyl, alkylhetrocycle, alkylphosphate, alkylphosphorothioate, alkylphosphorodithioate, alkylphosphonates, alkylamines, hydroxyalkyls, ω-aminoalkyls, ω-(substituted)aminoalkyls, ω-phosphoalkyls, ω-thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40K), optionally substituted mPEG (mw 120-40K), heteroaryl, heterocycle, or linker-ligand; E is O, S, N(Q), C(O), N(Q)C(O), C(O)N(Q), (Q)N(CO)O, O(CO)N(Q), S(O), NS(O)₂N(Q), S(O)₂, N(Q)S(O)₂, SS, O═N, aryl, heteroaryl, cyclic or heterocycle; and, Q is H, alkyl, ω-aminoalkyl, ω-(substituted)aminoalky, ω-phosphoalkyl or ω-thiophosphoalkyl.
FILED	Tuesday, May 23, 2017
APPL NO	15/603069
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 39/00 (20130101) A61K 39/39 (20130101) A61K 47/10 (20130101) A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 47/28 (20130101) A61K 47/44 (20130101) Original (OR) Class A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) Acyclic or Carbocyclic Compounds C07C 229/08 (20130101) C07C 229/30 (20130101) C07C 237/16 (20130101) C07C 251/38 (20130101) C07C 251/78 (20130101) C07C 271/12 (20130101) C07C 271/20 (20130101) C07C 323/25 (20130101) Heterocyclic Compounds C07D 203/10 (20130101) C07D 317/28 (20130101) C07D 317/44 (20130101) C07D 317/46 (20130101) C07D 317/72 (20130101) C07D 319/06 (20130101) C07D 405/12 (20130101) C07D 491/056 (20130101) C07D 491/113 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) Technologies for Adaptation to Climate Change Y02A 50/464 (20180101)
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10117942 — Photoactivatable lipid-based nanoparticles as vehicles for dual agent delivery

US 10117942	Puri et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Baylor College of Medicine (Houston, Texas)
INVENTOR(S)	Anu Puri (Frederick, Maryland); Robert P. Blumenthal (Bethesda, Maryland); Amit Joshi (Houston, Texas); Darayash B. Tata (Silver Spring, Maryland); Mathias Viard (Frederick, Maryland)
ABSTRACT	Embodiments of photoactivatable, lipid-based nanoparticles are disclosed, as well as methods of making and using the nanoparticles. Pharmaceutical compositions including the nanoparticles also are disclosed. The lipid-based nanoparticles include a vesicle wall surrounding a cavity, wherein the vesicle wall includes (i) a lipid bilayer comprising 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC_8,9PC), dipalmitoylphosphatidylcholine (DPPC), and (ii) 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) within the lipid bilayer. The nanoparticles may further include an agent within the cavity.
FILED	Wednesday, July 09, 2014
APPL NO	14/904385
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1271 (20130101) A61K 31/704 (20130101) A61K 41/0042 (20130101) A61K 41/0071 (20130101) A61K 47/546 (20170801) A61K 47/6911 (20170801) A61K 47/48069 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/067 (20130101) A61N 2005/0663 (20130101)
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10117943 — Synthetic antibody mimetic compounds (SYAMS) targeting cancer, especially prostate cancer

US 10117943	Spiegel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD)
APPLICANT(S)	YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S)	YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S)	David A. Spiegel (New Haven, Connecticut); Patrick McEnaney (Jupiter, Florida); Kelly Fitzgerald (Upton, Massachusetts)
ABSTRACT	The present invention relates to compounds which function as antibody mimetic compounds. These compounds are bifunctional/multifunctional compounds which contain at least one cancer cell binding moiety which selectively binds to prostate specific membrane antigen (PSMA) and a FC receptor binding moiety which modulates an FC immune receptor, preferably a FcγRI receptor. Compounds according to the present invention bind selectively to cancer cells which upregulate PSMA and through that interaction, place the Fc receptor binding moiety of the compound in proximity to a Fc receptor, preferably a FcγRI receptor, which can modulate (preferably, upregulate) a humoral response in a patient to cancer cells. Through this biological action of the compounds according to the present invention, cancer cells, including metastatic cancer cells, especially prostate cancer cells can be immune regulated, resulting in the favorable therapy of cancer in a patient. Methods of using these compounds to treat cancer and/or reduce the likelihood of metastatis of cancer are additional aspects of the present invention.
FILED	Friday, May 03, 2013
APPL NO	14/888779
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) A61K 47/55 (20170801) A61K 47/481 (20130101) Original (OR) Class Heterocyclic Compounds C07D 249/04 (20130101) C07D 249/06 (20130101)
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10117947 — Virus-like particle conjugates for diagnosis and treatment of tumors

US 10117947	de los Pinos et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Aura Biosciences, Inc. (Cambridge, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	Aura Biosciences, Inc. (Cambridge, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Elisabet de los Pinos (Brookline, Massachusetts); John Todd Schiller (Kensington, Maryland); Rhonda C. Kines (Washington, District of Columbia); John MacDougall (Hingham, Massachusetts)
ABSTRACT	The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles conjugated to photosensitive molecules.
FILED	Thursday, September 18, 2014
APPL NO	15/023169
ART UNIT	1675 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 41/0057 (20130101) A61K 41/0071 (20130101) A61K 47/6901 (20170801) A61K 47/48246 (20130101) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/585 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 16/32 (20130101) C07K 16/084 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20023 (20130101) C12N 2710/20033 (20130101) C12N 2710/20034 (20130101)
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10117948 — Selective arylation of dichalcogenides in biomolecules

US 10117948	Buchwald et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Stephen L. Buchwald (Newton, Massachusetts); Bradley L. Pentelute (Cambridge, Massachusetts); Daniel T. Cohen (Brighton, Massachusetts); Chi Zhang (Cambridge, Massachusetts)
ABSTRACT	Disclosed are chemical transformations for the conjugation of unprotected peptide biomolecules. The disclosed chemical transformations relate to methods of selective cysteine and selenocysteine functionalization of unprotected peptide and protein molecules. The processes feature several significant advantages over existing methods of peptide modification, including specificity towards selenocysteine over other nucleophiles (e.g., amines, hydroxyls), excellent functional group tolerance, and mild reaction conditions. Also disclosed are syntheses of arylated cysteine and arylated selenocysteine peptide compounds.
FILED	Monday, June 20, 2016
APPL NO	15/187169
ART UNIT	1675 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/14 (20130101) A61K 47/64 (20170801) A61K 47/6851 (20170801) A61K 47/48246 (20130101) Original (OR) Class Peptides C07K 1/13 (20130101) C07K 1/1075 (20130101) C07K 1/1077 (20130101) C07K 9/008 (20130101) C07K 14/47 (20130101)
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10117954 — Compositions and methods for in vivo imaging

US 10117954	Reiner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Thomas Reiner (Weehawken, New Jersey); Edmund J. Keliher (Topsfield, Massachusetts); Ralph Weissleder (Peabody, Massachusetts)
ABSTRACT	This document relates to compounds useful for targeting PARP1. Also provided herein are methods for using such compounds to detect and image cancer cells.
FILED	Friday, April 28, 2017
APPL NO	15/581386
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0021 (20130101) A61K 51/0459 (20130101) Original (OR) Class A61K 51/1251 (20130101)
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10117990 — Microfluidic intravital window

US 10117990	Castracane et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York); ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York)
ASSIGNEE(S)	The Research Foundation for the State University of New York (Albany, New York); Albert Einstein College of Medicine, Inc. (Bronx, New York)
INVENTOR(S)	James Castracane (Albany, New York); Logan Butt (Albany, New York); David Entenberg (Granite Springs, New York); Lauren Sfakis (Albany, New York); John Condeelis (Bronx, New York)
ABSTRACT	A microfluidic intravital window includes an intravital imaging window adapted for implantation adjacent target tissue of a live animal, and a microfluidic fluid source and delivery system physically integrated into the window for controlled delivery of fluids to target tissue via the window. The microfluidic fluid source and delivery system is self-contained and completely located within the intravital imaging window, and includes at least one preloaded fluid reservoir, at least one fluid port in fluidic communication with both the at least one preloaded fluid reservoir and the target tissue, and at least one light activated fluid flow control device situated between the at least one preloaded fluid reservoir and at least one fluid port, to facilitate simultaneous in vivo viewing and remotely controlled fluid delivery to the target tissue.
FILED	Wednesday, December 07, 2016
APPL NO	15/371493
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/150007 (20130101) A61B 17/0218 (20130101) Veterinary Instruments, Implements, Tools, or Methods A61D 1/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/172 (20130101) A61M 5/14276 (20130101) Original (OR) Class A61M 37/0015 (20130101) A61M 39/24 (20130101) A61M 2037/0023 (20130101) A61M 2039/2493 (20130101)
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10118169 — Chiral ligand-based metal-organic frameworks for broad-scope asymmetric catalysis

US 10118169	Lin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The University of Chicago (Chicago, Illinois); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Wenbin Lin (Chicago, Illinois); Joseph M. Falkowski (Annandale, New Jersey); Takahiro Sawano (Chicago, Illinois)
ABSTRACT	Metal-organic framework (MOFs) compositions based on chiral phosphine-, chiral oxazoline-, chiral pyridine-, and chiral diene-derived organic bridging ligands were synthesized and then post-synthetically metalated with metal precursors such as Ru and Rh complexes. The metal complexes could also be directly incorporated into the MOFs. The MOFs provide a versatile family of recyclable and reusable single-site solid catalysts for catalyzing a variety of asymmetric organic transformations, including the addition of arylboronic acids to α,β-unsaturated ketones and alkimines, the hydrogenation of substituted alkene and carbonyl compounds, and cyclization reactions. The solid catalysts can also be integrated into a flow reactor or a supercritical fluid reactor.
FILED	Monday, March 30, 2015
APPL NO	15/129851
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1691 (20130101) Original (OR) Class B01J 31/1805 (20130101) B01J 31/2409 (20130101) B01J 31/2447 (20130101) B01J 2531/0263 (20130101) B01J 2531/0266 (20130101) B01J 2531/822 (20130101) Acyclic or Carbocyclic Compounds C07C 29/44 (20130101) C07C 41/09 (20130101) C07C 45/69 (20130101) C07C 67/303 (20130101) C07C 227/04 (20130101) C07C 231/02 (20130101) C07C 2102/44 (20130101) Heterocyclic Compounds C07D 307/93 (20130101)
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10118827 — Combustion synthesis of calcium phosphate constructs and powders doped with atoms, molecules, ions, or compounds

US 10118827	Ayers et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Reed A. Ayers (Golden, Colorado); Nina L. Vollmer (Lakewood, Colorado)
ASSIGNEE(S)
INVENTOR(S)	Reed A. Ayers (Golden, Colorado); Nina L. Vollmer (Lakewood, Colorado)
ABSTRACT	The invention relates to a synthetic bone material and a process for making the same. The synthetic bone material may comprise multiple phases of calcium phosphate. Another aspect of the invention is a porous filter, and the method of making the same, and wherein the porous filter is substantially similar to the process for forming the synthetic bone material.
FILED	Monday, May 12, 2014
APPL NO	14/275641
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/12 (20130101) A61L 27/54 (20130101) A61L 2300/102 (20130101) A61L 2300/104 (20130101) A61L 2430/02 (20130101) Separation B01D 39/2068 (20130101) Non-metallic Elements; Compounds Thereof; C01B 25/32 (20130101) Original (OR) Class
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10118896 — Antagonists of the kappa opioid receptor

US 10118896	Aube et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	University of Kansas (Lawrence, Kansas)
ASSIGNEE(S)	UNIVERSITY OF KANSAS (Lawrence, Kansas); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S)	Jeffrey Aube (Lawrence, Kansas); Kevin Frankowski (Lawrence, Kansas); Thomas Prisinzano (Lawrence, Kansas); Laura Bohn (Jupiter, Florida)
ABSTRACT	The present technology is directed to compounds, compositions, and methods related to non-morphinan-like kappa opioid receptor (KOR) antagonists. The technology is suited to treat addiction, diuresis, depression, post traumatic stress disorder, an eating disorder, panic disorder, social anxiety disorder, general anxiety disorder, obsessive compulsive disorders, excessive or unreasonable specific phobias, and/or other conditions related to anxiety or aversion-reward responses.
FILED	Wednesday, November 25, 2015
APPL NO	15/529290
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 209/44 (20130101) C07D 217/08 (20130101) Original (OR) Class C07D 223/16 (20130101)
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10118903 — Aminotriazole-based KDM1A inhibitors as epigenetic modulators

US 10118903	Woster et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) National Cancer Institute (NCI)
APPLICANT(S)	MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina)
ASSIGNEE(S)	MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina)
INVENTOR(S)	Patrick M. Woster (Charleston, South Carolina); Craig J. Kutz (Johns Island, South Carolina)
ABSTRACT	In some aspects, the present invention provides compounds of the formula (IV), wherein the variables are as defined herein, which may be used as inhibitors of histone demethylase or spermine oxidase. Also provided herein are pharmaceutical compositions of the compounds and methods using the compounds in the treatment of diseases such as cancer and cardiovascular disease.
FILED	Friday, February 06, 2015
APPL NO	15/115342
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 249/14 (20130101) Original (OR) Class C07D 257/06 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101)
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10118910 — Benzothiophene-based selective estrogen receptor downregulators

US 10118910	Thatcher et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Gregory R. Thatcher (Urbana, Illinois); Rui Xiong (Urbana, Illinois); Jiong Zhao (Urbana, Illinois); Debra A. Tonetti (Urbana, Illinois)
ABSTRACT	This invention is benzothiophene-based estrogen receptor downregulators and their compositions and uses to treat estrogen-related medical disorders.
FILED	Friday, December 09, 2016
APPL NO	15/374966
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 333/64 (20130101) Original (OR) Class C07D 409/06 (20130101) C07D 409/12 (20130101)
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10118914 — Beta-arrestin-biased cannabinoid CB1 receptor agonists and methods for making and using them

US 10118914	Reggio et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	The University of North Carolina at Greensboro (Greensboro, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Greensboro (Greensboro, North Carolina)
INVENTOR(S)	Patricia H. Reggio (Greensboro, North Carolina); Derek M. Shore (Pine Hall, North Carolina); Dow P. Hurst (Greensboro, North Carolina)
ABSTRACT	The present invention provides compounds having a CB₁receptor-binding moiety and a directing moiety. In related aspects, the invention provides pharmaceutical compositions containing compounds of the invention, methods for inhibiting a pathway modulated in part by the CB₁receptor activity, and methods for treating a condition or disorder mediated in part by CB₁receptor activity. In certain embodiments, the compounds are compounds of Formula I. Methods of preparing compounds of Formula I are also described. In another aspect, the invention provides methods of identifying a selective agonist of the beta-arrestin pathway over the G-protein pathway.
FILED	Monday, December 19, 2016
APPL NO	15/383922
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 209/42 (20130101) C07D 401/12 (20130101) C07D 405/12 (20130101) Original (OR) Class
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10118915 — Kappa opioid ligands

US 10118915	Roberts et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Edward Roberts (Fallbrook, California); Miguel A. Guerrero (San Diego, California); Mariangela Urbano (Del Mar, California); Hugh Rosen (La Jolla, California)
ABSTRACT	The invention provides novel ligands of Kappa (κ) opioid receptors, such as can be used to modulate a Kappa opioid receptor. Methods of synthesis and methods of use are also provided. Compounds of the invention can be used therapeutically in the treatment of dissociative disorders or pain, or to provide neuroprotection, or to induce diuresis, or to modulate the immune system, or for treatment of one or more of an affective disorders comprising depression or stress/anxiety; an addictive disorder; alcoholism, epilepsy; a cognition deficiency; schizophrenia; Alzheimer's disease; or pain.
FILED	Monday, May 15, 2017
APPL NO	15/595436
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 211/58 (20130101) C07D 401/04 (20130101) C07D 405/14 (20130101) Original (OR) Class C07D 413/14 (20130101)
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10118923 — Compositions and methods for inhibiting kinases

US 10118923	Werner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Inhibikase Therapeutics, Inc. (Atlanta, Georgia)
ASSIGNEE(S)	Inhibikase Therapeutics, Inc. (Atlanta, Georgia)
INVENTOR(S)	Milton H. Werner (Marietta, Georgia); Terence A. Kelly (Ridgefield, Connecticut)
ABSTRACT	The present invention provides compounds for the prevention or treatment of cancer or a bacterial or viral infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the prevention or treatment of cancer or a bacterial or viral infection in a subject.
FILED	Tuesday, November 07, 2017
APPL NO	15/805693
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/393 (20180101) Y02A 50/467 (20180101) Y02A 50/473 (20180101) Y02A 50/475 (20180101) Y02A 50/481 (20180101)
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10118928 — Treatment of H. pylori infections using MTAN inhibitors

US 10118928	Schramm et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York); VICTORIA LINK LIMITED (Wellington, New Zealand)
ASSIGNEE(S)	Albert Einstein College of Medicine, Inc. (Bronx, New York); Victoria Link Limited (Wellington, New Zealand)
INVENTOR(S)	Vern L. Schramm (New Rochelle, New York); Keith Clinch (Lower Hutt, New Zealand); Shivali Ashwin Gulab (Wellington, New Zealand)
ABSTRACT	Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H. pylori MTAN (5′-methylthioadenosine nucleosidase) to the subject, where the inhibitors have the structure
FILED	Friday, February 06, 2015
APPL NO	15/118113
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/471 (20180101) Y02A 50/473 (20180101) Y02A 50/475 (20180101) Y02A 50/481 (20180101)
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10118934 — Inhibitors of UDP-galactopyranose mutase

US 10118934	Kiessling et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Laura L. Kiessling (Madison, Wisconsin); Virginia A. Kincaid (Madison, Wisconsin); Nir London (Rehovot, Israel); Brian K. Shoichet (Kentfield, California)
ABSTRACT	Compounds and salts thereof which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention include triazolothiadiazines, particularly 3, 6, 7-substituted-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines, and 4-(1H-pyrrol-3-yl) thiazoles, particularly 4-(1,2,5-substituted-1H-pyrrol-3-yl)-2-substituted thiazoles, and salts thereof. Methods for inhibiting growth or attenuating virulence of microbial pathogens including mycobacterium, for example, M. tuberculosis and M. smegmatis and Klebsiella, for example, Klebsiella pneumoniae. Methods for inhibiting eukaryotic human and animal pathogens, and fungi and nematodes in particular. Methods for treatment of infections by prokaryotic and eukaryotic pathogens employing compounds of the invention.
FILED	Wednesday, June 14, 2017
APPL NO	15/622972
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 417/04 (20130101) C07D 513/04 (20130101) Original (OR) Class
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10118935 — Melampomagnolide B dimers

US 10118935	Janganati et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	BioVentures, LLC (Little Rock, Arkansas); The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
ASSIGNEE(S)	BioVentures, LLC (Little Rock, Arizona); The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S)	Venumadhav Janganati (Little Rock, Arkansas); Peter Crooks (Little Rock, Arkansas); Narsimha Reddy Penthala (Little Rock, Arkansas); Craig Jordan (Denver, Colorado); Shobanbabu Bommagani (Little Rock, Arkansas); Jessica Ponder (Denver, Colorado)
ABSTRACT	The present disclosure provides dimers of melampomagnolide B (MMB), including carbamate, carbonate, succinic amide, ester and carboxamide dimers of MMB. These derivatives are useful for treating cancer in humans, in particular in treating leukemia, including acute myelogenous leukemia (AML).
FILED	Thursday, April 19, 2018
APPL NO	15/957524
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 519/00 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1852 (20130101)
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10118936 — Arginase inhibitors and methods of use

US 10118936	Christianson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	ASTRAZENECA AB (Sodertalje, Sweden); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); AstraZeneca AB (Sodertalje, Sweden)
INVENTOR(S)	David W. Christianson (Media, Pennsylvania); Bruce Edward Tomczuk (Collegeville, Pennsylvania); Richard Scott Pottorf (Belle Mead, New Jersey); Andrew Vargha Colasanti (Scotch Plains, New Jersey); Gary Lee Olson (Mountainside, New Jersey)
ABSTRACT	The present invention is directed to arginase inhibitor compounds of formula IA or formula IB: or a pharmaceutically acceptable salt thereof, compositions containing these compounds, and methods of their use for the treatment and diagnosis of conditions characterized by upregulation of arginase, abnormally high arginase activity, or by abnormally low nitric oxide synthase activity.
FILED	Friday, December 04, 2015
APPL NO	14/959765
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class
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10118938 — Arsenoplatin anti-cancer agents

US 10118938	Miodragovic et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Denana U. Miodragovic (Chicago, Illinois); Thomas V. O'Halloran (Chicago, Illinois)
ABSTRACT	Disclosed herein are methods of treating a cancer cell that include contacting a cancer cell with a compound having the structure of formula (I) M is Pt, Pd or Ni; Q is As, Sb or Bi; Z¹is N; Z²is O or S; L¹and L²are independently C(O), C—R¹or C—R²; X is a Lewis base; Y¹and Y²are independently selected from —OR³, —OR⁴, —SR³and —SR⁴, wherein R¹and R²are independently selected from hydrogen, halogen, cyano, keto, ester, ether, thiol, thioether, thioester, imino, C₁-C₁₀alkyl, C₁-C₁₀alkenyl, alkynyl, alkoxyl, amino, amidyl, immino, sulfonyl, sulfoxyl, phosphoryl, phosphoryl ester, glycosyl, aryl, C₃-C₁₅cycloalkyl, heteroaryl, and C₃-C₁₅heterocycloalkyl; and R³and R⁴are independently selected from hydrogen, C₁-C₁₀alkyl, C₁-C₁₀alkenyl, alkynyl, alkoxyl, amino, amidyl, immino, sulfonyl, sulfoxyl, phosphoryl, phosphoryl ester, glycosyl, aryl, C₃-C₁₅cycloalkyl, heteroaryl, and C₃-C₁₅heterocycloalkyl.
FILED	Thursday, June 29, 2017
APPL NO	15/637179
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/29 (20130101) A61K 31/282 (20130101) A61K 31/285 (20130101) A61K 31/295 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0013 (20130101) Original (OR) Class C07F 15/045 (20130101) C07F 15/0066 (20130101) C07F 15/0093 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101)
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10118942 — Toll-like receptor 2 ligands and methods of making and using thereof

US 10118942	Morse et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S)	H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); The Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona); University of South Florida (Tampa, Florida)
INVENTOR(S)	David L. Morse (Tampa, Florida); Josef Vagner (Tucson, Arizona); Mark McLaughlin (Tampa, Florida); Robert Gillies (Tampa, Florida); Amanda Huynh (Land O Lakes, Florida); Michael Doligalski (Lutz, Florida)
ABSTRACT	Disclosed are monoacylated Toll-like receptor 2 ligands which can be used in both the development of targeted agents for the imaging and treatment of pancreatic cancer as well as other cancers, and as an adjuvant for cancer immunotherapy. The monoacylated compounds disclosed herein have a higher binding affinity for TLR2 relative to a known potent diacylated agonists, but only −½ the bioactivity. Competition of the monoacylated compound with the diacylated compound for binding TLR2 was confirmed. Hence, the reported monoacylated compounds are inhibitors/antagonists of TLR2 activation.
FILED	Friday, March 25, 2016
APPL NO	15/561230
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/0019 (20130101) A61K 49/0032 (20130101) A61K 49/0052 (20130101) A61K 51/0497 (20130101) Peptides C07K 5/081 (20130101) Original (OR) Class
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10118945 — Dereplication strain of Aspergillus nidulans

US 10118945	Oakley et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	University of Kansas (Lawrence, Kansas); The University of Southern California (Los Angeles, California)
ASSIGNEE(S)	University of Kansas (Lawrence, Kansas); University of Southern California (Los Angeles, California)
INVENTOR(S)	Berl Oakley (Lawrence, Kansas); Manmeet Ahuja (Navi Mumba, India); Ruth Entwistle (Lawrence, Kansas); Christine Oakley (Lawrence, Kansas); Yi-Ming Chiang (Temple City, California); Clay Wang (San Marino, California)
ABSTRACT	Modified fungal strains having deleted gene clusters are provided. The modified fungal strains include A. nidulans. The deleted gene clusters are selected from the group of gene clusters responsible for the biosynthesis of sterigmatocystin, emericellamides, asperfuranone, monodictyphenone, terrequinone, F9775A, F9775B, asperthecin, and both portions of the split cluster that makes austinol and dehydroaustinol. Methods for making compounds by culturing the fungus in a growth media and separating the compound from the fungus and/or separating the compound from the growth media are included, as are the compounds and compositions comprising them.
FILED	Monday, October 31, 2016
APPL NO	15/338696
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 7/06 (20130101) Original (OR) Class
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10118948 — Antimicrobial peptides, pharmaceutical compositions, and methods of use thereof

US 10118948	Zheng et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland)
INVENTOR(S)	Jie Zheng (Columbia, Maryland); Ann Marie Knolhoff (Silver Spring, Maryland); Eric Wayne Brown (Taneytown, Maryland); Timothy Ray Croley (Severna Park, Maryland)
ABSTRACT	Disclosed herein are novel antimicrobial peptides, pharmaceutical compositions containing the peptides, and methods of use of the peptides to inhibit the growth or proliferation of microbes. The antimicrobial peptides are particularly useful to treat infections of dangerous gram positive organisms such as MRSA and VRSA.
FILED	Wednesday, December 07, 2016
APPL NO	15/371683
ART UNIT	1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/10 (20130101) A61K 47/48038 (20130101) Peptides C07K 7/08 (20130101) C07K 7/56 (20130101) Original (OR) Class C07K 19/00 (20130101)
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10118996 — Polyrotaxanes and uses thereof

US 10118996	Thompson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	David H. Thompson (West Lafayette, Indiana); Seok-Hee Hyun (West Lafayette, Indiana); Kyle J. Wright (West Lafayette, Indiana)
ABSTRACT	A polyrotaxane containing an affinity binding group has been designed and prepared. The polyrotaxane of the invention can be used for characterization and determination of the three-dimensional structures of biological molecules, such as proteins.
FILED	Friday, February 22, 2013
APPL NO	13/774302
ART UNIT	1678 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Polysaccharides; Derivatives Thereof C08B 37/0012 (20130101) C08B 37/0015 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/007 (20130101) Original (OR) Class Derivatives of Natural Macromolecular Compounds C08H 1/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101)
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10119003 — Surfactant-based monolithic columns, methods for making the same, and methods for using the same

US 10119003	Shamsi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
ASSIGNEE(S)	Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
INVENTOR(S)	Shahab Ahmed Shamsi (Tucker, Georgia); Congying Gu (Lansing, Michigan); Jun He (Atlanta, Georgia)
ABSTRACT	A method for making a surfactant-based monolithic column is provided. The method comprises providing a mixture comprising at least one surfactant monomer, at least one crosslinker, at least one initiator, and at least one porogen and polymerizing the mixture to form the surfactant-based monolithic column. The present disclosure also provides a surfactant-based monolithic column, a method for separating molecules, and a process for preparing a surfactant monomer.
FILED	Friday, May 03, 2013
APPL NO	13/886921
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/261 (20130101) B01J 20/267 (20130101) B01J 20/285 (20130101) B01J 20/28042 (20130101) B01J 2220/82 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/127 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2030/528 (20130101)
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10119109 — Automated, multifunctional, engineered cardiac tissue culture and testing bioreactor system

US 10119109	Costa et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	Icahn School of Medicine at Mount Sinai (New York, New York)
ASSIGNEE(S)	ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York)
INVENTOR(S)	Kevin D. Costa (New York, New York); Peter Backeris (Union City, New Jersey)
ABSTRACT	An improved tissue engineering bioreactor and testing platform has been designed that integrates multiple testing and stimulation capabilities. The system allows for growth of multiple tissue strips in parallel with mechanical and electrical stimulation, media perfusion, and the automated monitoring of contractile force and extracellular electrical activity. The system is designed to be low-cost and scalable, to provide for high-content, biofidelic, non-destructive testing of engineered muscle tissue performance that is conventionally measured using muscle-bath systems.
FILED	Tuesday, August 25, 2015
APPL NO	15/504570
ART UNIT	1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 23/12 (20130101) C12M 23/22 (20130101) C12M 23/38 (20130101) C12M 23/50 (20130101) C12M 31/10 (20130101) C12M 35/02 (20130101) C12M 41/46 (20130101) C12M 41/48 (20130101)
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10119123 — Cell fate conversion of differentiated somatic cells into glial cells

US 10119123	Tesar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Paul J. Tesar (Cleveland, Ohio); Robert H. Miller (Cleveland, Ohio); Fadi J. Najm (Cleveland, Ohio)
ABSTRACT	The present invention relates to the reprogramming of differentiated somatic cells, such as those differentiated cells that arise from embryonic mesoderm, into glial cells. Glial cells produced from this reprogramming are functionally equivalent to glial cells that arise from ectodermal origins.
FILED	Tuesday, November 08, 2016
APPL NO	15/346453
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2501/41 (20130101) C12N 2501/60 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2506/1307 (20130101)
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10119124 — Influenza M2 protein mutant viruses as live influenza attenuated vaccines

US 10119124	Watanabe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
INVENTOR(S)	Tokiko Watanabe (Tokyo, Japan); Yoshihiro Kawaoka (Middleton, Wisconsin)
ABSTRACT	A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus.
FILED	Thursday, October 13, 2016
APPL NO	15/292595
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/16121 (20130101) C12N 2760/16134 (20130101)
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10119133 — Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

US 10119133	Joung et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	J. Keith Joung (Winchester, Massachusetts); Jeffry D. Sander (Ames, Iowa); Yan-fang Fu (Malden, Massachusetts); Morgan Maeder (Brookline, Massachusetts)
ABSTRACT	CRISPR-Cas genome editing uses a guide RNA, which includes both a complementarity region, which binds the target DNA by base-pairing, and a Cas9-binding region, to direct a Cas9 nuclease to a target DNA. Further disclosed are methods for increasing specificity of RNA-guided genome editing using CRISPR/Cas9 systems by using truncated guide RNAs (tru-gRNAs).
FILED	Friday, March 14, 2014
APPL NO	14/775930
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 2319/00 (20130101) C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) C12N 9/0071 (20130101) C12N 9/96 (20130101) C12N 9/1007 (20130101) C12N 15/01 (20130101) C12N 15/63 (20130101) C12N 15/85 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 2710/00033 (20130101) C12N 2770/00033 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 114/11 (20130101) C12Y 201/01 (20130101) C12Y 301/00 (20130101) C12Y 301/21004 (20130101)
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10119139 — Treatment for conditions associated with fibrosis and collagen deposition

US 10119139	Harrison et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee); Yale University (New Haven, Connecticut)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee); Yale University (New Haven, Connecticut)
INVENTOR(S)	David G. Harrison (Nashville, Tennessee); Kim Ramil Montaniel (Antioch, Tennessee); Kasey C. Vickers (Franklin, Tennessee); Jing Wu (Lexington, Kentucky); Jay D. Humphrey (Madison, Connecticut); Matthew R. Bersi (Nashville, Tennessee)
ABSTRACT	Methods, compositions, devices, and kits for treating and/or reducing the risk of developing a condition associated with fibrosis and/or collagen deposition are provided. The method of treating and/or reducing the risk of developing a condition associated with fibrosis and/or collagen deposition in a subject includes administering an effective amount a miRNA-762 inhibitor to the subject, wherein the subject is identified as having a risk of developing and/or a need for treatment of the condition associated with fibrosis and/or collagen deposition. The kit includes a vial containing an miRNA-762 inhibitor and a device for use in a surgery creating a risk of fibrosis and/or collagen deposition. The composition includes a pharmaceutical composition comprising a miRNA-762 inhibitor and a second agent selected from the group consisting of: an angiotensin-converting enzyme (ACE) inhibitors, an angiotensin receptor blocker (ARB), another antihypertensive agent, a steroid, and combinations thereof.
FILED	Wednesday, September 14, 2016
APPL NO	15/265813
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/22 (20130101) A61B 2017/22001 (20130101) A61B 2017/22051 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/322 (20130101) C12N 2310/3231 (20130101) C12N 2320/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101)
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10119140 — Methods for enhancing or decreasing the levels of MIR124 and MIR29 in subjects with muscular dystrophy

US 10119140	Singer et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	Board of Regents of the Nevada System of Higher Education, on Behalf of The University of Nevada (Reno, Nevada)
ASSIGNEE(S)	BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (Reno, Nevada)
INVENTOR(S)	Cherie A. Singer (Sparks, Nevada); Ryan Wuebbles (Reno, Nevada); Dean Burkin (Reno, Nevada)
ABSTRACT	Disclosed herein are methods of treating and diagnosing muscular dystrophy. In some examples, the methods include treating muscular dystrophy by administering to the subject a therapeutically effective amount of an agent that alters the expression of at least one miR gene product, such as miRNA-124 and/or miRNA-29 thereby treating muscular dystrophy. In one particular example, the method of treatment includes administering an agent that decreases the expression or activity of miRNA-124. In another embodiment, the method of treatment includes administering a composition that includes one or more agents to decrease the expression and/or activity of miRNA-124 and one or more agents to alter the activity of miRNA-29 (increase or decrease). Also disclosed are methods of enhancing muscle regeneration, repair, or maintenance in a subject and methods of enhancing α7β1 integrin expression. Methods of prospectively preventing or reducing muscle injury or damage in a subject are also disclosed.
FILED	Friday, April 17, 2015
APPL NO	15/305058
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/141 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101)
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10119144 — Polycomb-associated non-coding RNAs

US 10119144	Lee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Jeannie T. Lee (Boston, Massachusetts); Jing Zhao (San Diego, California); Kavitha Sarma (Waltham, Massachusetts); Mark Borowsky (Needham, Massachusetts); Toshiro Kendrick Ohsumi (Cambridge, Massachusetts)
ABSTRACT	This invention relates to long non-coding RNAs (lncRNAs), libraries of those ncRNAs that bind chromatin modifiers, such as Polycomb Repressive Complex 2, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
FILED	Monday, February 22, 2016
APPL NO	15/050273
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 15/1136 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/113 (20130101) C12N 2310/141 (20130101) C12N 2310/314 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/346 (20130101) C12N 2310/3181 (20130101) C12N 2310/3231 (20130101) C12N 2310/3233 (20130101) C12N 2320/30 (20130101) C12N 2320/32 (20130101) C12N 2330/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6881 (20130101) C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Enzymes C12Y 201/01043 (20130101)
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10119148 — RNAs from pathogens inhibit plant immunity

US 10119148	Jin
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Hailing Jin (Riverside, California)
ABSTRACT	The present invention relates to pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
FILED	Thursday, October 02, 2014
APPL NO	14/505378
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8282 (20130101) Original (OR) Class
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10119160 — Methods of identifying homologous genes using FISH

US 10119160	Wu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Chao-ting Wu (Brookline, Massachusetts); Brian Beliveau (Cambridge, Massachusetts)
ABSTRACT	The present invention relates to methods of hybridizing nucleic acid probes to genomic DNA.
FILED	Friday, January 06, 2017
APPL NO	15/399788
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6841 (20130101) Original (OR) Class C12Q 1/6841 (20130101) C12Q 1/6844 (20130101) C12Q 1/6853 (20130101) C12Q 2543/10 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101)
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10119165 — Nucleic acid constructs and methods of use

US 10119165	Chee
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Prognosys Biosciences, Inc. (San Diego, California)
ASSIGNEE(S)	PROGNOSYS BIOSCIENCES, INC. (La Jolla, California)
INVENTOR(S)	Mark S. Chee (Encinitas, California)
ABSTRACT	The present invention provides oligonucleotide constructs, sets of such oligonucleotide constructs, and methods of using such oligonucleotide constructs to provide validated sequences or sets of validated sequences corresponding to desired ROIs. Such validated ROIs and constructs containing these have a wide variety of uses, including in synthetic biology, quantitative nucleic acid analysis, polymorphism and/or mutation screening, and the like.
FILED	Friday, November 11, 2016
APPL NO	15/349927
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/131 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2539/103 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101)
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10119170 — Detection of chromosomal region copy number changes to diagnose melanoma

US 10119170	Bastian et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Boris Bastian (Mill Valley, California); Daniel Pinkel (Lafayette, California)
ABSTRACT	This invention provides methods of detecting melanoma. The methods comprises detecting a gain or loss of certain chromosomal regions that undergo copy number changes in melanoma.
FILED	Wednesday, January 13, 2016
APPL NO	14/994977
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101)
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10119172 — Methods and reagents for detecting ebola virus

US 10119172	Stroeher et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Ute Stroeher (Atlanta, Georgia); Tara Sealy (Atlanta, Georgia); Jonathan Towner (Decatur, Georgia); Stuart Nichol (Atlanta, Georgia); César Albariño (Atlanta, Georgia)
ABSTRACT	Probes and primers are disclosed for detecting EBOV nucleic acid in a sample. Methods are also disclosed that utilize these probes and primers, wherein the methods can be used to detect an EBOV in a sample to identify a subject with an EBOV infection.
FILED	Thursday, February 18, 2016
APPL NO	15/552157
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/701 (20130101) Original (OR) Class
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10119958 — Arrays and methods for guided cell patterning

US 10119958	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Miqin Zhang (Bothell, Washington); Mandana Veiseh (Emeryville, California)
ABSTRACT	Guided cell patterning arrays for single cell patterning are disclosed. The arrays include a plurality of cell adhesion sites that are individually isolated on an inert surface. Each cell adhesion site has one or more cell adhesion peptides having affinity to a cell surface receptor. The inert surface is resistant to cell adhesion.
FILED	Tuesday, August 25, 2015
APPL NO	14/835224
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 20/02 (20130101) C40B 40/02 (20130101) C40B 60/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/5008 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02164 (20130101)
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10119959 — Method of assaying an individual for immune impairment

US 10119959	Shen-Orr et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Shai S. Shen-Orr (Menlo Park, California); Atul J. Butte (Menlo Park, California); Mark M. Davis (Atherton, California); David Furman (San Francisco, California); Brian A. Kidd (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Shai S. Shen-Orr (Menlo Park, California); Atul J. Butte (Menlo Park, California); Mark M. Davis (Atherton, California); David Furman (San Francisco, California); Brian A. Kidd (Palo Alto, California)
ABSTRACT	Embodiments of the present invention provide diagnostic markers of immunosenescence and methods of identifying individuals with impaired immune function based on a combination of such markers obtained from various analyzes, primarily from blood, testing immune function including the analysis of immune cell subset frequencies, gene expression, cytokine and chemokine levels, and signaling responses to stimulation with cytokines (‘cytokine response’). Particular combinations of markers can predict with high accuracy whether an individual will respond to active vaccination and become protected against recurring diseases.
FILED	Saturday, June 25, 2011
APPL NO	13/168974
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) Original (OR) Class G01N 2333/52 (20130101) G01N 2333/70514 (20130101) G01N 2333/70517 (20130101) G01N 2333/70521 (20130101) G01N 2800/60 (20130101)
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10119974 — Isobaric tandem mass tags for quantitative proteomics and peptidomics

US 10119974	Li et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Lingjun Li (Madison, Wisconsin); Feng Xiang (Midland, Michigan); Tyler Greer (Middleton, Wisconsin); Dustin Frost (Madison, Wisconsin); Zhidan Liang (Madison, Wisconsin)
ABSTRACT	Compositions and methods of tagging peptides and other molecules using novel isobaric tandem mass tagging reagents, including novel N, N-dimethylated amino acid 8-plex and 16-plex isobaric tandem mass tagging reagents. The tagging reagents comprise: a) a reporter group having at least one atom that is optionally isotopically labeled; b) a balancing group, also having at least one atom that is optionally isotopically labeled, and c) an amine reactive group. The tagging reagents disclosed herein serve as attractive alternatives for isobaric tag for relative and absolute quantitation (iTRAQ) and tandem mass tags (TMTs) due to their synthetic simplicity, labeling efficiency and improved fragmentation efficiency.
FILED	Tuesday, June 14, 2016
APPL NO	15/182329
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Heterocyclic Compounds C07D 207/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class
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10119977 — Therapeutic and diagnostic methods for autism spectrum disorders and other conditions

US 10119977	Nath et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Balimore, Maryland)
INVENTOR(S)	Avindra Nath (Ellicott City, Maryland); Tongguang Wang (Lutherville, Maryland); Christina Michelle Morris-Berry (Baltimore, Maryland); Harvey Singer (Baltimore, Maryland)
ABSTRACT	The present invention relates to the field of autism. More specifically, the present invention provides methods for treating individuals with autism spectrum disorders. The present invention also provides methods for predicting a likelihood of ASD. In one embodiment, a method for treating a female patient having a high risk factor of having children with ASD comprises the steps of (a) identifying in a sample taken from the female patient the presence of AT-1 antibodies; and (b) administering an effective amount of an AT-1 inhibitor or inhibitor of AT-1 antibodies to the female patient.
FILED	Friday, April 22, 2016
APPL NO	15/136021
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) A61K 31/4525 (20130101) A61K 31/7105 (20130101) Peptides C07K 16/2869 (20130101) C07K 2317/10 (20130101) C07K 2317/21 (20130101) C07K 2317/73 (20130101) C07K 2317/75 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2333/705 (20130101) G01N 2333/726 (20130101) G01N 2800/30 (20130101) G01N 2800/50 (20130101)
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10120049 — System and method of obtaining spatially-encoded NMR parameters from arbitrarily-shaped compartments and linear algebraic modeling

US 10120049	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Yi Zhang (Baltimore, Maryland); Jinyuan Zhou (Cockeysville, Maryland); Paul A. Bottomley (Columbia, Maryland)
ABSTRACT	An NMR method and system for acquiring and reconstructing a value of an NMR parameter spatially localized to a compartment of interest including performing a first MM of a portion of a sample with a first MRI pulse sequence using the NMR system and using a set of k-space spatial encoding gradients or coil sensitivity encoding maps to obtain a first magnetic resonance image to identify a compartment of interest; generating a second MRI pulse sequence that encodes the NMR parameter with a subset of the set of k-space spatial encoding gradients or the coil sensitivity encoding maps; applying the second MRI pulse sequence using the NMR system to acquire spatial information relating to the NMR parameter from the compartment of interest; segmenting the first magnetic resonance image into a plurality of compartments that includes the compartment of interest; and reconstructing a value of the NMR parameter in the compartment.
FILED	Monday, May 18, 2015
APPL NO	14/715367
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/483 (20130101) Original (OR) Class G01R 33/485 (20130101) G01R 33/5605 (20130101) G01R 33/5611 (20130101) G01R 33/56341 (20130101) G01R 33/56366 (20130101)
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10120180 — Methods and apparatus for stretched light field microscope

US 10120180	Ben Ezra et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Moshe Ben Ezra (Jersey City, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Christopher Rowlands (Cambridge, Massachusetts); Young Gyu Yoon (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Moshe Ben Ezra (Jersey City, New Jersey); Edward Boyden (Chestnut Hill, Massachusetts); Christopher Rowlands (Cambridge, Massachusetts); Young Gyu Yoon (Cambridge, Massachusetts)
ABSTRACT	The information budget of a light field microscope is increased by increasing the field of view and image circle diameter of the microscope, while keeping the ratio of overall magnification of the microscope to the numerical aperture of the microscope unchanged. Alternatively, the information budget is increased by increasing the field of view and image circle diameter of the microscope by a first factor, while increasing the ratio of overall magnification of the microscope to the numerical aperture of the microscope by a smaller, second factor. In some cases, an infinity-corrected light field microscope has an overall magnification that is greater than the nominal magnification of the objective lens.
FILED	Monday, September 28, 2015
APPL NO	14/868340
ART UNIT	2488 — Recording and Compression
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 21/0004 (20130101) G02B 21/361 (20130101) Original (OR) Class G02B 21/367 (20130101)
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10121245 — Identification of inflammation in tissue images

US 10121245	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	UNIVERSITY OF NOTRE DAME (South Bend, Indiana); UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	UNIVERSITY OF NOTRE DAME (South Bend, Indiana)
INVENTOR(S)	Danny Ziyi Chen (Granger, Indiana); Jiazhuo Wang (Sunnyvale, California); John DeWolfe MacKenzie (San Francisco, California); Rageshree Ramachandran (San Francisco, California)
ABSTRACT	Systems and methods are provided for identifying markers for inflammation in a tissue image. The tissue image is captured as an image of a histology slide. Subcellular structures in the tissue image are segmented via a first automated process to identify at least one variety of immune cells within the image. Glands and vilii are identified within the tissue image via a second automated process. Neutrophils are identified within the tissue image via a third automated process. An output representing the identified glands, villi, neutrophils, and other immune cells is provided to a human operator.
FILED	Wednesday, September 14, 2016
APPL NO	15/264836
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/48 (20130101) G06K 9/00147 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/12 (20170101) G06T 7/162 (20170101) G06T 2207/10024 (20130101) G06T 2207/10056 (20130101) G06T 2207/30024 (20130101)
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10121645 — Sheathless interface for capillary electrophoresis/electrospray ionization-mass spectrometry

US 10121645	Lunte et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	The University of Kansas (Lawrence, Kansas)
ASSIGNEE(S)	National Institutes of Health (NIH) U.S. Department of Health and Human Services (DHHS), U.S. Government NIH Division of Extramural Inventions and Technology Resources (DEITR) (Bethesda, Maryland)
INVENTOR(S)	Craig E. Lunte (Lawrence, Kansas); Ryan Tyler Johnson (Lawrence, Kansas); Nhan To (Lawrence, Kansas); Susan M. Lunte (Lawrence, Kansas); Damon Osbourn (St. Louis, Missouri)
ABSTRACT	Provided herein are capillaries for use in an electrophoretic separations. The capillaries can comprise an elongated tubular wall defining a path for fluid flow from an inlet to a tapered outlet; and a decoupler junction positioned within the elongated tubular wall upstream of the tapered outlet. The decoupler junction can comprise a plurality of microchannels penetrating through the elongated tubular wall and an ion-permeable polymer coating the plurality of microchannels. Also provided are sheathless interfaces for coupling capillary electrophoresis (CE) with mass spectrometry that employ these capillaries.
FILED	Tuesday, December 05, 2017
APPL NO	15/832016
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44713 (20130101) G01N 30/7233 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/167 (20130101) Original (OR) Class H01J 49/0431 (20130101)
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Department of Defense (DOD)

10117436 — Antimicrobial polymeric compositions

US 10117436	Wynne et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Virginia Commonwealth University (Richmond, Virginia)
ASSIGNEE(S)	VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia)
INVENTOR(S)	Kenneth J. Wynne (Midlothian, Virginia); Souvik Chakrabarty (Ithaca, New York); Wei Zhang (Midlothian, Virginia); Asima Chakravorty (Richmond, Virginia); Olufemi O. Oyesanya (Chesapeake, Virginia)
ABSTRACT	A compound having the formula: wherein n, y, R₁and R₂are defined herein, and others, methods of making of and using, and compositions made thereby which have an antimicrobial resistance effect are described.
FILED	Thursday, March 24, 2016
APPL NO	15/080567
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 55/00 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/184 (20130101) C07F 7/1804 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/61 (20130101) C08G 18/718 (20130101) C08G 18/758 (20130101) C08G 18/4862 (20130101) C08G 18/5066 (20130101) C08G 18/6674 (20130101) C08G 65/18 (20130101) C08G 65/22 (20130101) C08G 65/226 (20130101) C08G 65/336 (20130101) C08G 2650/04 (20130101) C08G 2650/38 (20130101) C08G 2650/48 (20130101) C08G 2650/50 (20130101) C08G 2650/64 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/04 (20130101)
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10117859 — Dosage suspensions of active pharmaceutical ingredients

US 10117859	Dixon et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Southwest Research Institute (San Antonio, Texas)
ASSIGNEE(S)	SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas)
INVENTOR(S)	Hong Dixon (Helotes, Texas); Larry A. Cabell (San Antonio, Texas); Joseph A. McDonough (Helotes, Texas)
ABSTRACT	Methods for preparing suspensions of active pharmaceutical ingredients for ensuing drug delivery. The suspension may include a mixture of a relatively low dosage API and a relatively high dosage API or a mixture of an API with a suitable excipient.
FILED	Monday, June 27, 2016
APPL NO	15/193254
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 31/444 (20130101) Original (OR) Class A61K 31/5375 (20130101)
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10118005 — Delivery system

US 10118005	Yoo et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) Armed Forces Institute of Regenerative Medicine (AFIRM) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S)	WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina)
INVENTOR(S)	James J. Yoo (Winston-Salem, North Carolina); Anthony Atala (Winston-Salem, North Carolina); Kyle W. Binder (Winston-Salem, North Carolina); Mohammad Z. Albanna (Winston-Salem, North Carolina); Weixin Zhao (Winston-Salem, North Carolina); Dennis Dice (Yadkinville, North Carolina); Tao Xu (El Paso, Texas)
ABSTRACT	Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.
FILED	Friday, September 06, 2013
APPL NO	14/019714
ART UNIT	3778 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0064 (20130101) A61B 5/445 (20130101) A61B 5/1077 (20130101) A61B 5/1079 (20130101) A61B 5/6835 (20130101) A61B 34/30 (20160201) A61B 90/50 (20160201) A61B 2017/00969 (20130101) A61B 2017/3225 (20130101) A61B 2034/105 (20160201) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/60 (20130101) A61L 27/225 (20130101) A61L 27/3813 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/00 (20130101) Original (OR) Class A61M 35/00 (20130101) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 3/4073 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101)
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10118054 — Implants using ultrasonic backscatter for sensing physiological conditions

US 10118054	Maharbiz et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Michel M. Maharbiz (El Cerrito, California); Jose M. Carmena (Berkeley, California); Mekhail Anwar (San Francisco, California); Burak A. Ozilgen (Berkeley, California); Dongjin Seo (Albany, California); Federica Fava (Berkeley, California)
ABSTRACT	Described herein is an implantable device having a sensor configured to detect an amount of an analyte, a pH, a temperature, strain, or a pressure; and an ultrasonic transducer with a length of about 5 mm or less in the longest dimension, configured to receive current modulated based on the analyte amount, the pH, the temperature, or the pressure detected by the sensor, and emit an ultrasonic backscatter based on the received current. The implantable device can be implanted in a subject, such as an animal or a plant. Also described herein are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also described are methods of detecting an amount of an analyte, a pH, a temperature, a strain, or a pressure.
FILED	Tuesday, September 12, 2017
APPL NO	15/702301
ART UNIT	3737 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/076 (20130101) A61B 5/686 (20130101) A61B 5/4836 (20130101) A61B 6/4258 (20130101) A61B 8/48 (20130101) A61B 8/085 (20130101) A61B 8/0808 (20130101) A61B 8/0875 (20130101) A61B 2505/05 (20130101) A61B 2560/0219 (20130101) A61B 2562/12 (20130101) A61B 2562/028 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 39/0208 (20130101) A61M 2205/04 (20130101) A61M 2205/825 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/3605 (20130101) A61N 1/3787 (20130101) A61N 1/37205 (20130101) A61N 5/1071 (20130101) A61N 7/02 (20130101) Original (OR) Class A61N 2005/1087 (20130101) A61N 2007/0021 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/025 (20130101) H02J 50/15 (20160201) H02J 50/90 (20160201)
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10118060 — Select Schiff base compounds for chemical agent detoxification

US 10118060	Owens et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Jeffery Ray Owens (Panama City, Florida); Wallace Bruce Salter (Panama City, Florida); Katherine Moss Simpson (Panama City, Florida)
ABSTRACT	A Schiff base compound configured to detoxify a toxic chemical agent. The toxic chemical agent includes at least one leaving group and the Schiff base compound includes an imine having at least one Lewis base and an alkyl substituent or an aryl substituent having an electron acceptor. The at least one Schiff base nitrogen is spaced way from the electron acceptor by a distance that ranges from about 200 pm to about 1000 pm.
FILED	Wednesday, September 18, 2013
APPL NO	14/029952
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/36 (20130101) Original (OR) Class A62D 2101/02 (20130101) A62D 2101/22 (20130101) A62D 2101/26 (20130101) A62D 2101/28 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 13/272 (20130101) D06M 13/335 (20130101) D06M 13/352 (20130101) D06M 13/355 (20130101) D06M 16/00 (20130101)
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10118315 — Preparing tool surfaces for composites

US 10118315	Cheng et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Aerospace Materials Processing, LLC (Redondo Beach, California)
ASSIGNEE(S)	Surfx Technologies LLC (Redondo Beach, California)
INVENTOR(S)	Siu F. Cheng (Culver City, California); Mikhail M. Grigoriev (Albequerque, New Mexico); Robert F. Hicks (Los Angeles, California)
ABSTRACT	Techniques for producing composites outside of an autoclave that have smooth surface finishes are disclosed. The smooth composite surface, free of porosity, can be fabricated by curing the prepreg in a tool that includes a novel microstructure. In conventional composite manufacturing, some degree of porosity appears to originate from trapped gas bubbles that form during curing. The microstructure can provide a mechanism for the gas bubbles to escape from the tooling, thereby eliminating porosity and yielding a smooth surface finish on the out-of-autoclave composite. The microstructure can be applied to the tool surface using an inkjet process applying an acrylic resin curable with ultraviolet light.
FILED	Tuesday, May 06, 2014
APPL NO	14/271428
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/42 (20130101) Original (OR) Class B29C 33/3842 (20130101) B29C 67/0055 (20130101) B29C 70/00 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2863/00 (20130101) B29K 2879/00 (20130101) B29K 2905/00 (20130101) B29K 2905/02 (20130101) B29K 2907/04 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201)
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10118426 — Nanoporous stamp for flexographic printing

US 10118426	Hart et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S)	Anastasios John Hart (Somerville, Massachusetts); Sanha Kim (Cambridge, Massachusetts); Hossein Sojoudi (Medford, Massachusetts); Karen K. Gleason (Cambridge, Massachusetts)
ABSTRACT	A nanoporous stamp for printing a variety of materials is disclosed. The nanoporous stamp may include a substrate and an array of carbon nanotubes disposed on and attached to the substrate. The array of carbon nanotubes can have an etched top surface and a wettable, nanoporous structure, and may include a coating thereon. The nanoporous stamp can be used in a variety of printing applications, and can print, among other things, colloidal and non-colloidal inks on a variety of substrates with a high degree of accuracy and fidelity.
FILED	Wednesday, November 25, 2015
APPL NO	14/951854
ART UNIT	2854 — Printing/Measuring and Testing
CURRENT CPC	Processes for the Manufacture or Reproduction of Printing Surfaces B41C 1/00 (20130101) B41C 1/05 (20130101) Printing Machines or Presses B41F 5/24 (20130101) Stamps; Stamping or Numbering Apparatus or Devices B41K 3/62 (20130101) Original (OR) Class Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 1/04 (20130101) Printing Plates or Foils; Materials for Surfaces Used in Printing Machines for Printing, Inking, Damping, or the Like; Preparing Such Surfaces for Use and Conserving Them B41N 1/12 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) G03F 7/0015 (20130101)
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10118938 — Arsenoplatin anti-cancer agents

US 10118938	Miodragovic et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Denana U. Miodragovic (Chicago, Illinois); Thomas V. O'Halloran (Chicago, Illinois)
ABSTRACT	Disclosed herein are methods of treating a cancer cell that include contacting a cancer cell with a compound having the structure of formula (I) M is Pt, Pd or Ni; Q is As, Sb or Bi; Z¹is N; Z²is O or S; L¹and L²are independently C(O), C—R¹or C—R²; X is a Lewis base; Y¹and Y²are independently selected from —OR³, —OR⁴, —SR³and —SR⁴, wherein R¹and R²are independently selected from hydrogen, halogen, cyano, keto, ester, ether, thiol, thioether, thioester, imino, C₁-C₁₀alkyl, C₁-C₁₀alkenyl, alkynyl, alkoxyl, amino, amidyl, immino, sulfonyl, sulfoxyl, phosphoryl, phosphoryl ester, glycosyl, aryl, C₃-C₁₅cycloalkyl, heteroaryl, and C₃-C₁₅heterocycloalkyl; and R³and R⁴are independently selected from hydrogen, C₁-C₁₀alkyl, C₁-C₁₀alkenyl, alkynyl, alkoxyl, amino, amidyl, immino, sulfonyl, sulfoxyl, phosphoryl, phosphoryl ester, glycosyl, aryl, C₃-C₁₅cycloalkyl, heteroaryl, and C₃-C₁₅heterocycloalkyl.
FILED	Thursday, June 29, 2017
APPL NO	15/637179
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/29 (20130101) A61K 31/282 (20130101) A61K 31/285 (20130101) A61K 31/295 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0013 (20130101) Original (OR) Class C07F 15/045 (20130101) C07F 15/0066 (20130101) C07F 15/0093 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101)
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10118950 — Platforms for cell-free protein synthesis comprising extracts from genomically recoded E. coli strains having genetic knock-out mutations in release factor 1 (RF-1) and endA

US 10118950	Jewett et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Michael Christoper Jewett (Evanston, Illinois); Rey William Martin (Evanston, Illinois); Seok Hoon Hong (Chicago, Illinois); Yong Chan Kwon (Evanston, Illinois); Benjamin James Des Soye (Evanston, Illinois)
ABSTRACT	The invention relates to genomically recoded organisms, platforms for preparing sequence defined biopolymers in vitro comprising a cellular extract from a genomically recorded organism, and methods for preparing sequence defined biopolymers in vitro are described. In particular, the invention relates to genomically recoded organisms comprising a strain deficient in release factor 1 (RF-1) or a genetic homolog thereof and at least one of at least one additional genetic knock-out mutation, at least one additional upregulated gene product, or both at least one additional knock-out mutation and at least one additional upregulated gene product.
FILED	Monday, August 31, 2015
APPL NO	14/840249
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Peptides C07K 14/001 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1247 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) C12P 21/02 (20130101) Enzymes C12Y 207/07006 (20130101)
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10119035 — Abhesive coatings

US 10119035	Wynne et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Kenneth J. Wynne (Midlothian, Virginia); Wei Zhang (Henrico, Virginia); Chenyu Wang (Richmond, Virginia); Souvik Chakrabarty (Richmond, Virginia)
ASSIGNEE(S)	VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia)
INVENTOR(S)	Kenneth J. Wynne (Midlothian, Virginia); Wei Zhang (Henrico, Virginia); Chenyu Wang (Richmond, Virginia); Souvik Chakrabarty (Richmond, Virginia)
ABSTRACT	A monolithic, self-stratifying polymer coating, comprising: inner and outer-most surfaces on opposite sides of the coating, the inner surface being in contact with and adhered to an article; a surface region, extending from the outermost surface to a depth of about 2 nm from the outermost surface; a middle region, extending from a depth of about 2 nm from the outermost surface to a depth of less than about 2000 nm from the outermost surface; and a bulk region, extending from a depth of less than about 2000 nm from the outermost surface to the inner surface; wherein the surface region comprises a fluorous polyoxetane having the formula: (I) wherein n is an integer of 0-1 1, and m is an integer>0, in a greater concentration relative to the middle and bulk regions; wherein the middle region comprises 3F-SiO_1.5groups in a greater concentration relative to the surface and bulk regions; and wherein the bulk region comprises a polyurethane in a greater concentration relative to the surface and middle regions.
FILED	Thursday, July 26, 2012
APPL NO	14/235447
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/718 (20130101) C08G 18/758 (20130101) C08G 18/5015 (20130101) C08G 18/6674 (20130101) C08G 65/18 (20130101) C08G 65/226 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1662 (20130101) Original (OR) Class C09D 175/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1393 (20150115) Y10T 428/31551 (20150401)
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10119059 — Thermoelastic cooling

US 10119059	Cui et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Jun Cui (Richland, Washington); Ichiro Takeuchi (Laurel, Maryland); Manfred Wuttig (Silver Spring, Maryland); Yiming Wu (Greenbelt, Maryland); Reinhard Radermacher (Silver Spring, Maryland); Yunho Hwang (Ellicott City, Maryland); Jan Muehlbauer (Bowie, Maryland)
ASSIGNEE(S)	Jun Cui (Ames, Iowa); THE UNIVERSITY OF MARYLAND (College Park, Maryland)
INVENTOR(S)	Jun Cui (Richland, Washington); Ichiro Takeuchi (Laurel, Maryland); Manfred Wuttig (Silver Spring, Maryland); Yiming Wu (Greenbelt, Maryland); Reinhard Radermacher (Silver Spring, Maryland); Yunho Hwang (Ellicott City, Maryland); Jan Muehlbauer (Bowie, Maryland)
ABSTRACT	A cooling system based on thermoelastic effect is provided. The system comprises a heat sink, a refrigerated space and a regenerator coupled to the refrigerated space and to the heat sink to pump heat from the refrigerated space to the heat sink. The regenerator comprises solid thermoelastic refrigerant materials capable of absorbing or releasing heat.
FILED	Tuesday, March 27, 2012
APPL NO	13/431768
ART UNIT	3744 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/00 (20130101)
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10119195 — Multichannel cold spray apparatus

US 10119195	Mohanty et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Pravansu S. Mohanty (Canton, Michigan); Vikram Varadaraajan (Novi, Michigan)
ABSTRACT	A cold spray apparatus for applying a coating of particles to a substrate includes a nozzle assembly having a plurality of inner passages terminating at a common exit. The nozzle assembly includes a particle supply members in communication with the inner passages. The particle supply members supply the particles to flow and accelerate through the inner passages and out of the nozzle assembly via the common exit toward the substrate to be coated thereon. Furthermore, each inner passage includes a laser that emits a laser beam that is transmitted through the inner passage. The laser heats at least one of the particles and the substrate to promote coating of the substrate with the particles.
FILED	Monday, October 17, 2016
APPL NO	15/295050
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/16 (20130101) B05B 7/0075 (20130101) B05B 7/228 (20130101) B05B 7/1404 (20130101) B05B 7/1481 (20130101) Apparatus for Applying Fluent Materials to Surfaces, in General B05C 19/008 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/12 (20130101) B05D 3/06 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/144 (20151001) B23K 26/1476 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/04 (20130101) Original (OR) Class C23C 24/08 (20130101) C23C 24/082 (20130101) C23C 24/085 (20130101)
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10119266 — Extensible sparse-isogrid column

US 10119266	Jeon et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Sungeun K. Jeon (Albuquerque, New Mexico); Jeremy Banik (Albuquerque, New Mexico); Michael Peterson (Albuquerque, New Mexico)
ASSIGNEE(S)	The Government of the United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Sungeun K. Jeon (Albuquerque, New Mexico); Jeremy Banik (Albuquerque, New Mexico); Michael Peterson (Albuquerque, New Mexico)
ABSTRACT	A sparse-isogrid columnar lattice structure including rigid ring frames connected by a mirrored symmetric double helix pattern comprised of first shell hinge elements in a first helical pattern and second shell hinge elements in a second helical pattern oriented in an opposite direction to the first helical pattern and congruent thereto. The helical axes of the first and second helical patterns intersect the respective centers of the ring frames. The first and second shell hinge elements are configured to stow in a stored energy state when the ring frames are collapsed toward one another along the helical axis, and the first and second shell hinge elements are configured to release the stored energy to deploy to a restored state and extend the ring frames apart from each other along the helical axis when deployed to form a stable rigid axial column in a restored state.
FILED	Thursday, December 22, 2016
APPL NO	15/388647
ART UNIT	3638 — Static Structures, Supports and Furniture
CURRENT CPC	Cosmonautics; Vehicles or Equipment Therefor B64G 1/10 (20130101) B64G 1/222 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/19 (20130101) E04B 1/344 (20130101) E04B 1/34357 (20130101) Original (OR) Class
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10119403 — Mistuned concentric airfoil assembly and method of mistuning same

US 10119403	Hayford et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Richard K. Hayford (Cape Neddick, Maine); Steven J. Ford (Sanford, Maine)
ABSTRACT	An example method of reducing a vibratory response of airfoils that support a shroud includes circumferentially misaligning some of the airfoils in a radially inner array of airfoils with all airfoils of a radially outer array of airfoils, and circumferentially aligning at least one of the airfoils in the radially inner array of airfoils with all airfoils of the radially outer array of airfoils.
FILED	Tuesday, February 10, 2015
APPL NO	14/618478
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/022 (20130101) F01D 5/146 (20130101) Original (OR) Class F01D 5/225 (20130101) F01D 25/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/961 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/673 (20130101)
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10119410 — Vane seal system having spring positively locating seal member in axial direction

US 10119410	Rogers et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	United Technologies Corporation (Hartford, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Mark J. Rogers (Kennebunk, Maine); Carl S. Richardson (South Berwick, Maine); Richard K. Hayford (Cape Neddick, Maine); Kenneth E. Carman (Kennebunk, Maine); Jonathan J. Earl (Wells, Maine)
ABSTRACT	A vane seal system includes a non-rotatable vane segment that has an airfoil with a pocket at one end thereof. The pocket spans in an axial direction between forward and trailing sides, with respect to the airfoil, and in a lateral direction between open lateral sides. A seal member extends in the pocket. The seal member includes a seal element and at least one spring portion that is configured to positively locate the seal member in the axial direction in the pocket. A method for positioning the seal member in a vane seal system includes positively locating the seal member in the axial direction in the pocket using the spring portion.
FILED	Tuesday, September 23, 2014
APPL NO	15/026011
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/001 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/38 (20130101)
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10119449 — Systems and methods for restraining exhaust gas ducts

US 10119449	Boekeloo et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Aviation and Missile Center (CCDC AVMC)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S)	Eric Matthews Boekeloo (Seattle, Washington); William Preston Keith (Lakewood, California); Michael Best (Huntington Beach, California); Aristidis Sidiropoulos (Huntington Beach, California); Thomas Richardson Pinney (Long Beach, California)
ABSTRACT	Methods and systems for restricting movement in a flow mixer of an exhaust duct, the flow mixer having a first row of flutes and a second row of flutes generally opposite to the first row of flutes, each flute being elongated and defining an elongated axis. At least two flute ties connect, or couple, together at least two flutes from the first row of flutes and at least two flutes from the second row of flutes. A retainer is coupled to the flute ties and extends generally perpendicularly to the elongated axis of each of the flutes from the first and second rows of flutes. The combination of the retainer and flute ties is configured to generally restrain relative movement between the flutes from the first row and the flutes from the second row.
FILED	Tuesday, August 02, 2016
APPL NO	15/226451
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 29/00 (20130101) B64D 2033/045 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 13/082 (20130101) Original (OR) Class F01N 2590/00 (20130101) Jet-propulsion Plants F02K 1/48 (20130101) F02K 1/80 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/30 (20130101) F05D 2260/96 (20130101)
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10119589 — Microlattice damping material and method for repeatable energy absorption

US 10119589	Schaedler et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Tobias A. Schaedler (Oak Park, California); Alan J. Jacobsen (Woodland Hills, California); William Carter (Calabasas, California); Christopher P. Henry (Thousand Oaks, California); Chia-Ming “Gavin” Chang (Agoura Hills, California); Geoffrey P. McKnight (Los Angeles, California); Andrew P. Nowak (Los Angeles, California)
ABSTRACT	Described is a micro-lattice damping material and a method for repeatable energy absorption. The micro-lattice damping material is a cellular material formed of a three-dimensional interconnected network of hollow tubes. This material is operable to provide high damping, specifically acoustic, vibration or shock damping, by utilizing the energy absorption mechanism of hollow tube buckling, which is rendered repeatable by the micro-lattice architecture.
FILED	Wednesday, January 15, 2014
APPL NO	14/156242
ART UNIT	1781 — Miscellaneous Articles, Stock Material
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/00 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/10 (20130101) B32B 3/12 (20130101) B32B 2307/51 (20130101) B32B 2307/56 (20130101) B32B 2307/72 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/007 (20130101) B81B 3/0035 (20130101) B81B 3/0067 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00126 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 30/02 (20130101) C04B 30/02 (20130101) C04B 35/00 (20130101) C04B 38/04 (20130101) C04B 2111/40 (20130101) C04B 2111/52 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/00 (20130101) C23C 18/00 (20130101) C23C 26/00 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/00 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 7/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/26 (20150115) Y10T 428/1234 (20150115) Y10T 428/12361 (20150115) Y10T 428/12375 (20150115) Y10T 428/12479 (20150115) Y10T 428/24149 (20150115) Y10T 428/24273 (20150115) Y10T 428/24661 (20150115) Y10T 428/249953 (20150401)
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10119703 — Method for low power non-coking liquid hydrocarbon fuel vaporization and supercritical phase change

US 10119703	Clark
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	David A. Clark (Cleveland Heights, Ohio)
ABSTRACT	Methods for vaporizing hydrocarbon fuel and delivering the hydrocarbon fuel in either a vaporized phase or a supercritical phase to, for example, a combustion chamber are provided herein. A method of vaporizing a hydrocarbon fuel, wherein the hydrocarbon fuel is in a liquid phase at a first temperature and a first pressure, and wherein the first temperature of the liquid phase hydrocarbon fuel is less than its intrinsic oxidation or endothermic reaction temperature, the method may include lowering a pressure of the liquid phase hydrocarbon fuel from the first pressure to a second pressure; and heating the liquid phase hydrocarbon fuel from the first temperature to a second temperature, wherein the hydrocarbon fuel at the second temperature and the second pressure is in a substantially completely vaporized phase substantially without thermally oxidizing the hydrocarbon fuel, and wherein the hydrocarbon fuel in the substantially completely vaporized phase does not form carbonaceous contaminants.
FILED	Thursday, March 14, 2013
APPL NO	13/803206
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Methods of Steam Generation; Steam Boilers F22B 1/18 (20130101) Burners F23D 11/445 (20130101) Original (OR) Class
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10119771 — Non-isotropic structures for heat exchangers and reactors

US 10119771	Kelly
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	John T. Kelly (Saratoga, California)
ASSIGNEE(S)	Altex Technologies Corporation (Sunnyvale, California)
INVENTOR(S)	John T. Kelly (Saratoga, California)
ABSTRACT	A Non-Isotropic Structure for a Heat Exchanger (NISHEX) that forms fins from nested woven wire meshes. The wire meshes are shaped into channels that are stacked on top of each other to produce a non-isotropic fin structure having multiple fin layers. The fin structure exhibits a high heat coefficient while maintaining relatively high fin efficiency through the selection of fin lengths in proportion to the wire diameter in the mesh fins.
FILED	Wednesday, January 04, 2012
APPL NO	13/343620
ART UNIT	3744 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/022 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/4935 (20150115)
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10119857 — Reflection-enhanced photo-detector

US 10119857	Li et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Guoliang Li (San Diego, California); Xuezhe Zheng (San Diego, California); Ying L. Luo (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ASSIGNEE(S)	ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California)
INVENTOR(S)	Guoliang Li (San Diego, California); Xuezhe Zheng (San Diego, California); Ying L. Luo (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT	An integrated optical device includes a photo-detector (such as germanium) optically coupled to an optical waveguide. This photo-detector is deposited on the optical waveguide, and an optical signal propagating in the optical waveguide may be evanescently coupled to the photo-detector. In order to increase the absorption length of the photo-detector, a mirror (such as a distributed Bragg reflection grating) is included in the optical waveguide near the end of the photo-detector. This mirror reflects the optical signal back toward the photo-detector, thereby increasing the absorption of the optical signal by the photo-detector. In addition, absorption may be reduced by using electrical contacts that are electrically coupled to the photo-detector at locations where the optical mode of the optical signal is largely in the underlying optical waveguide, and by using a fingered metal layer to couple to the electrical contacts.
FILED	Friday, August 17, 2012
APPL NO	13/588248
ART UNIT	2878 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 1/0209 (20130101) G01J 1/0407 (20130101) Original (OR) Class G01J 1/0425 (20130101) Optical Elements, Systems, or Apparatus G02B 6/124 (20130101) G02B 6/12004 (20130101)
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10119953 — Metal chalcogenide quantum dots for the detection of nitroaromatic chemicals

US 10119953	Baca et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Alfred J. Baca (Ridgecrest, California); Heather A. Meylemans (Camarillo, California); Lee R. Cambrea (Ridgecrest, California); Lawrence Baldwin (Ridgecrest, California)
ABSTRACT	The synthesis of AgInS₂based quantum dots and their use as fluorometric probes for the selective detection of nitroaromatic explosive chemicals, without the use of ligands specific to nitroaromatic explosive chemicals. These quantum dots allow the detection of nitroaromatic explosive molecules by eye. The present invention also represents a simple patterning method for quantum dots on substrates, including low cost filter paper. The ease of fabrication, use of less toxic materials, and the selectivity to nitroaromatic explosive chemicals results in a practical solution to the development of a portable fluorescent probe based on quantum dots for the detection of nitroaromatic explosive chemicals.
FILED	Friday, September 15, 2017
APPL NO	15/705731
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 15/006 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 25/04 (20130101) C06B 25/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/643 (20130101) G01N 21/4738 (20130101) G01N 21/6428 (20130101) G01N 31/22 (20130101) G01N 33/227 (20130101) Original (OR) Class G01N 2021/4766 (20130101)
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10119955 — High-resolution molecular sensor

US 10119955	Lieber et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Charles M. Lieber (Lexington, Massachusetts); Qihua Xiong (Singapore, Singapore); Ping Xie (Needham, Massachusetts); Ying Fang (Beijing, China PRC)
ABSTRACT	A solid state molecular sensor having an aperture extending through a thickness of a sensing material is configured with a continuous electrically-conducting path extending in the sensing material around the aperture. A supply reservoir is connected to provide a molecular species, having a molecular length, from the supply reservoir to an input port of the aperture. A collection reservoir is connected to collect the molecular species from an output port of the aperture after translocation of the molecular species from the supply reservoir through the sensing aperture. The sensing aperture has a length between the input and output ports, in the sensing material, that is substantially no greater than the molecular length of the molecular species from the supply reservoir. An electrical connection to the sensing material measures a change in an electrical characteristic of the sensing material during the molecular species translocation through the aperture.
FILED	Friday, February 21, 2014
APPL NO	14/186056
ART UNIT	1799 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) Original (OR) Class
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10119975 — Methods and systems for cell state quantification

US 10119975	Shetty et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Ginkgo Bioworks, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	Ginkgo Bioworks, Inc. (Boston, Massachusetts)
INVENTOR(S)	Reshma Shetty (Boston, Massachusetts); Thomas F. Knight, Jr. (Belmont, Massachusetts); Randall D. Rettberg (Concord, Massachusetts)
ABSTRACT	Systems, methods, libraries, kits, and computer software tools are provided for designing and producing engineered cells. Such engineered cells can be used for cell state quantification, such as genome, transcriptome and/or proteome quantification. In one aspect, an engineered cell having a plurality of artificially designed oligonucleotides introduced into the genome of the cell is provided. The oligonucleotides are each located in proximity of a gene of interest encoding a protein of interest, and are different from one another. The oligonucleotides can each encode a unique peptide tag for each protein of interest, wherein each peptide tag has a unique quantitatively measurable value such as mass-to-charge ratio which can be quantified by a mass spectrometer. The engineered cell is capable of expressing a plurality of proteins of interest each fused to its corresponding unique peptide tag, wherein each peptide tag is capable of being released therefrom.
FILED	Tuesday, November 29, 2016
APPL NO	15/363243
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/74 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class
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10120112 — Diffractive waveplate lenses for correcting aberrations and polarization-independent functionality

US 10120112	Tabirian et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Nelson V. Tabirian (Winter Park, Florida); David E. Roberts (Apopka, Florida); Diane M. Steeves (Franklin, Massachusetts); Brian R. Kimball (Shrewsbury, Massachusetts)
ASSIGNEE(S)	Beam Engineering for Advanced Measurements Co. (Orlando, Florida); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Nelson V. Tabirian (Winter Park, Florida); David E. Roberts (Apopka, Florida); Diane M. Steeves (Franklin, Massachusetts); Brian R. Kimball (Shrewsbury, Massachusetts)
ABSTRACT	Diffractive waveplate lenses, devices, systems and methods of fabricating and manufacturing lenses for correcting spherical and chromatic aberrations of diffractive waveplate lenses and refractive lenses, by using nonlinear patterning of anisotropy axis of birefringent layers comprising the diffractive waveplate lenses, and their combinations and for obtaining polarization-independent functionality of diffractive waveplate lenses.
FILED	Thursday, April 16, 2015
APPL NO	14/688256
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/1833 (20130101) Original (OR) Class G02B 5/3083 (20130101) G02B 27/4211 (20130101) G02B 27/4216 (20130101)
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10120127 — Multi-element optical links

US 10120127	Williams et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Keith J. Williams (Dunkirk, Maryland); Jason D. McKinney (Bowie, Maryland)
ABSTRACT	An apparatus includes an input radio frequency waveguide. The apparatus includes a radio-frequency-to-optical-radio-frequency-impedance-matching interface communicating with the input radio frequency waveguide. The apparatus includes a plurality of optical modulators communicating with the radio-frequency-to-optical-radio-frequency-impedance-matching interface. The apparatus includes a plurality of respective optical waveguides communicating with the plurality of optical modulators. The plurality of respective optical waveguides in operation includes a plurality of respective optical waveguide fields. The input radio frequency waveguide in operation includes an input radio frequency waveguide field. The input radio frequency waveguide field interacts with the plurality of respective optical waveguide fields to convert an input radio frequency signal into a plurality of optical signals.
FILED	Monday, October 02, 2017
APPL NO	15/722021
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/0208 (20130101) G02B 6/2938 (20130101) G02B 6/4203 (20130101) G02B 6/12004 (20130101) G02B 6/12019 (20130101) Original (OR) Class G02B 6/29323 (20130101) G02B 6/29361 (20130101)
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10120211 — Self-tuned silicon-photonic WDM transmitter

US 10120211	Zheng et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Oracle International Corporation (Redwood Shores, California)
ASSIGNEE(S)	Oracle International Corporation (Redwood Shores, California)
INVENTOR(S)	Xuezhe Zheng (San Diego, California); Ying Luo (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT	An optical transmitter includes: a set of reflective silicon optical amplifiers (RSOAs), a set of ring modulators, a shared broadband reflector, a set of intermediate waveguides, and a shared waveguide. Each intermediate waveguide channels light from an RSOA in proximity to an associated ring modulator to cause optically coupled light to circulate in the associated ring modulator. The shared waveguide is coupled to the shared broadband reflector, and passes in proximity to the set of ring modulators, so that light circulating in each ring modulator causes optically coupled light to flow in the shared optical waveguide. During operation, each RSOA forms a lasing cavity with the shared broadband reflector, wherein each lasing cavity has a different wavelength, which is determined by a resonance of the associated ring modulator. The different wavelengths are combined in the shared waveguide to produce a combined output.
FILED	Tuesday, November 08, 2016
APPL NO	15/346565
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/2938 (20130101) G02B 6/12007 (20130101) G02B 2006/12142 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) Original (OR) Class G02F 1/0147 (20130101) G02F 2203/15 (20130101) G02F 2203/055 (20130101) G02F 2203/70 (20130101) Multiplex Communication H04J 14/02 (20130101)
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10120263 — Low-duty-cycle continuous-wave photoconductive terahertz imaging and spectroscopy systems

US 10120263	Jarrahi
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Mona Jarrahi (Los Angeles, California)
ABSTRACT	Systems and methods for plasmonics enhanced photomixing for generating continuous-wave (CW) frequency-tunable terahertz radiation in accordance with embodiments of the invention are disclosed. A photomixing system configured to generate continuous-wave terahertz frequency signals can include an optical pump configured to generate at least two beams, where the at least two beams are utilized to create a frequency-offset and operate below a 50% duty cycle, where the duty cycle includes an operation cycle and a sleep cycle. The photomixing system can also include a photomixer that includes a radiating element configured to receive the frequency-offset and to generate a terahertz radiation utilizing the received frequency-offset and the radiating element, where the radiating element includes at least one plasmonic contact electrode.
FILED	Friday, June 12, 2015
APPL NO	15/318347
ART UNIT	2874 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3534 (20130101) Original (OR) Class G02F 2203/13 (20130101)
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10120836 — Gathering materials on the ocean surface based on forecasting area density

US 10120836	Jacobs et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Gregg Arthur Jacobs (Slidell, Louisiana); A. D. Kirwan, Jr. (Newark, Delaware); Helga S. Huntley (Newark, Delaware); Bruce L. Lipphardt, Jr. (Newark, Delaware)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Gregg Arthur Jacobs (Slidell, Louisiana); A. D. Kirwan, Jr. (Newark, Delaware); Helga S. Huntley (Newark, Delaware); Bruce L. Lipphardt, Jr. (Newark, Delaware)
ABSTRACT	Embodiments relate to gathering materials on an ocean surface. Initially, an initial distribution of material is determined based on observational sources, and the material is represented by particles in a numerical ocean model. Trajectories for the numerical ocean model are determined based on modeled surface currents data, and velocity gradients are computed along a corresponding trajectory of the trajectories for each of the particles based on the initial distribution. At this stage, deformation tensors are computed for each of the particles based on the velocity gradients, and a dilation map for the particles is generated based on a time step tensor of the plurality of deformation tensors for each of the particles. Collection of the material is monitored based on the dilation map.
FILED	Friday, February 12, 2016
APPL NO	15/043251
ART UNIT	2123 — AI & Simulation/Modeling
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 2211/02 (20130101) Electric Digital Data Processing G06F 17/13 (20130101) Original (OR) Class
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10120998 — Virtual browsing environment

US 10120998	Ghosh et al.
FUNDED BY	Department of Defense (DOD) Defense Contract Management Agency (DCMA) Department of the Army (DOA)
APPLICANT(S)	George Mason Research Foundation, Inc. (Fairfax, Virginia)
ASSIGNEE(S)	George Mason Research Foundation, Inc. (Fairfax, Virginia)
INVENTOR(S)	Anup K. Ghosh (Centreville, Virginia); Sushil Jajodia (Oakton, Virginia); Yih Huang (Fairfax, Virginia); Jiang Wang (Fairfax, Virginia)
ABSTRACT	An embodiment for providing a secure virtual browsing environment includes creating a virtual browsing environment with a virtualized operating system sharing an operating system kernel of a supporting operating system and executing the browser application within the virtual browsing environment. Another embodiment includes receiving a website selection within a browser application, determining if the website selection corresponds to a secure bookmark, and creating a second virtual browsing environment and executing the browser application within the second virtual browsing environment to access the website selection when the website selection corresponds to a website specified as a secure bookmark. Yet another embodiment includes monitoring operation of the operating system within the at least one virtual browsing environment, determining when the operation of the operating system includes potential malicious activity, and terminating the virtual browsing environment when the operation includes potential malicious activity.
FILED	Monday, August 29, 2016
APPL NO	15/249975
ART UNIT	2497 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 9/54 (20130101) G06F 21/53 (20130101) Original (OR) Class G06F 2221/034 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1408 (20130101) H04L 63/1483 (20130101)
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10121011 — Apparatus, method and article of manufacture for partially resisting hardware trojan induced data leakage in sequential logics

US 10121011	Kwiat et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY TE SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Kevin Kwiat (Whitesboro, New York); Charles Kamhoua (Liverpool, New York); Laurent Njilla (Rome, New York); Yiyu Shi (Granger, Indiana); Travis Schulze (St. Louis, Missouri)
ABSTRACT	Apparatus, method and article of manufacture providing a randomized encoding scheme for sequential logics, for resistance to data leakage. Invention employs dual-rail encoding to randomize the information in the chip, and employs three-dimensional integration technology to protect the critical information that is needed to decode the data anywhere on-chip. With the present invention, even when the entire design is completely known to the attacker who also has full access to the outsourced portion, it is still not always possible to identify the information in the chip using data leakage Trojans.
FILED	Tuesday, January 03, 2017
APPL NO	15/397142
ART UNIT	2435 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/60 (20130101) Original (OR) Class G06F 21/72 (20130101) G06F 21/79 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/02 (20130101) G10L 15/16 (20130101) G10L 25/21 (20130101) G10L 25/24 (20130101) G10L 25/84 (20130101) G10L 25/90 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/002 (20130101) H04L 45/02 (20130101) H04L 45/22 (20130101) H04L 45/54 (20130101) H04L 63/162 (20130101) H04L 2209/08 (20130101) H04L 2209/12 (20130101)
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10121234 — System and method for ghost removal in video footage using object bounding boxes

US 10121234	Cao et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Yongqiang Cao (Newton, Massachusetts); Narayan Srinivasa (Portland, Oregon)
ABSTRACT	Described is a system for ghost removal in video footage. During operation, the system generates a background subtraction map and an original bounding box that surrounds a detected foreground object through background subtraction. A detected foreground map is then generated. The detected foreground map includes at least two detected foreground (DF) bounding boxes of detected foregrounds obtained by a difference of two consecutive frames in video footage. Further, the original bounding box is then trimmed into a trimmed box, the trimmed box being a smallest box that contains the at least two DF bounding boxes. The trimmed box is designated as containing a real-world object, which can then be used for object tracking.
FILED	Thursday, April 06, 2017
APPL NO	15/481220
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/20021 (20130101) G06T 2207/20224 (20130101)
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10121294 — Rapid document detection and identification

US 10121294	Dishon et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
ASSIGNEE(S)	Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S)	John Dishon (San Diego, California); Joshua N. Edmison (Ellicott City, Maryland); John-Francis Mergen (Baltimore, Maryland); Zachary Leuschner (Annapolis, Maryland); Kerry Wood (Elkridge, Maryland); Laurie Waisel (Columbia, Maryland); Richard Burne (Ellicott City, Maryland); Tyler Shake (Baltimore, Maryland); Thomas Wilkerson (Baltimore, Maryland); Jason Fox (San Diego, California)
ABSTRACT	An apparatus, method, and computer program product that intentionally illuminate at least one target item with electromagnetic energy having specific characteristics (e.g., frequency, power, waveform, directionality, duration, etc.). The target item, which may be an unpowered data storage device or secure document, acts as a non-linear mixer and is forced to emit radiative signals containing information about the target item's state and physical characteristics. Embodiments receive the forced emissions, extract useful data, and analyze the data to determine target item characteristics (e.g., a target item type, based on a comparison of data from known types). Embodiments control the illumination so the forced emissions radiate from an enclosure without interfering with tactical communications, and so that stored target item data is not affected. Embodiments can locate a hidden target item via the strength and directionality of the forced emissions. The apparatus is portable for use by military, intelligence, and security personnel.
FILED	Monday, August 14, 2017
APPL NO	15/676518
ART UNIT	2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00463 (20130101) G06K 19/10 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/00007 (20130101) Original (OR) Class
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10121667 — Creation of hyperdoped semiconductors with concurrent high crystallinity and high sub-bandgap absorptance using nanosecond laser annealing

US 10121667	Mazur et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S)	President And Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Eric Mazur (Concord, Massachusetts); Benjamin Franta (Elkader, Iowa); Michael J. Aziz (Concord, Massachusetts); David Pastor (Cambridge, Massachusetts)
ABSTRACT	In one aspect, a method of processing a semiconductor substrate is disclosed, which comprises incorporating at least one dopant in a semiconductor substrate so as to generate a doped polyphase surface layer on a light-trapping surface, and optically annealing the surface layer via exposure to a plurality of laser pulses having a pulsewidth in a range of about 1 nanosecond to about 50 nanoseconds so as to enhance crystallinity of said doped surface layer while maintaining high above-bandgap, and in many embodiments sub-bandgap optical absorptance.
FILED	Thursday, November 12, 2015
APPL NO	15/524539
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0624 (20151001) B23K 26/0732 (20130101) B23K 26/0738 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02532 (20130101) H01L 21/2686 (20130101) Original (OR) Class H01L 29/0665 (20130101) H01L 31/036 (20130101) H01L 31/068 (20130101) H01L 31/0288 (20130101) H01L 31/1804 (20130101) H01L 31/1864 (20130101) H01L 31/1872 (20130101) H01L 31/02363 (20130101)
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10121712 — Accelerated failure test of coupled device structures under direct current bias

US 10121712	Ghassemi et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Hessam Ghassemi (Raleigh, North Carolina); Andrew C. Lang (Branchburg, New Jersey); Mitra L. Taheri (Philadelphia, Pennsylvania)
ASSIGNEE(S)	DREXEL UNIVERSITY (Philadelphia, Pennsylvania)
INVENTOR(S)	Hessam Ghassemi (Raleigh, North Carolina); Andrew C. Lang (Branchburg, New Jersey); Mitra L. Taheri (Philadelphia, Pennsylvania)
ABSTRACT	A method of conducting an in situ reliability test on a cross-section of a device with layered structure at micron-scale and at least two electrodes. The method includes steps of locating an electron transparent cross-sectional portion of the device in a holder and transmitting a direct current bias voltage to the cross-sectional portion of the device through at least two electrodes of the device, and observing and quantifying the microstructural changes of the device cross-section on the holder. A system for conducting an in situ reliability test on a device with a layered structure at a micron-scale and at least two electrodes is also provided.
FILED	Thursday, March 31, 2016
APPL NO	15/087187
ART UNIT	2894 — Semiconductors/Memory
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2642 (20130101) G01R 31/2644 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/14 (20130101) H01L 22/32 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 29/7786 (20130101)
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10121754 — Interconnect structures and methods for fabricating interconnect structures

US 10121754	Oliver et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	William D. Oliver (Arlington, Massachusetts); Andrew J. Kerman (Arlington, Massachusetts); Rabindra N. Das (Lexington, Massachusetts); Donna-Ruth W. Yost (Acton, Massachusetts); Danna Rosenberg (Arlington, Massachusetts); Mark A. Gouker (Belmont, Massachusetts)
ABSTRACT	A method of fabricating an interconnect structure includes providing a semiconductor structure and performing a first spin resist and bake cycle. The first spin resist and bake cycle includes applying a first predetermined amount of a resist material over one or more portions of the semiconductor structure and baking the semiconductor structure to form a first resist layer portion of a resist layer. The method also includes performing a next spin resist and bake cycle. The next spin resist and bake cycle includes applying a next predetermined amount of the resist material and baking the semiconductor structure to form a next resist layer portion of the resist layer. The method additionally includes depositing a conductive material in an opening formed in the resist layer and forming a conductive structure from the conductive material. An interconnect structure is also provided.
FILED	Thursday, November 03, 2016
APPL NO	15/342444
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02063 (20130101) H01L 21/02282 (20130101) H01L 21/02345 (20130101) H01L 22/26 (20130101) H01L 24/05 (20130101) H01L 24/11 (20130101) Original (OR) Class H01L 24/13 (20130101) H01L 24/81 (20130101) H01L 25/50 (20130101) H01L 25/0652 (20130101) H01L 25/0655 (20130101) H01L 25/0657 (20130101) H01L 27/18 (20130101) H01L 39/02 (20130101) H01L 2224/117 (20130101) H01L 2224/0401 (20130101) H01L 2224/0558 (20130101) H01L 2224/1111 (20130101) H01L 2224/04042 (20130101) H01L 2224/05111 (20130101) H01L 2224/05111 (20130101) H01L 2224/05116 (20130101) H01L 2224/05116 (20130101) H01L 2224/05169 (20130101) H01L 2224/05169 (20130101) H01L 2224/05609 (20130101) H01L 2224/05609 (20130101) H01L 2224/05644 (20130101) H01L 2224/05644 (20130101) H01L 2224/06181 (20130101) H01L 2224/8181 (20130101) H01L 2224/08503 (20130101) H01L 2224/11001 (20130101) H01L 2224/11005 (20130101) H01L 2224/11462 (20130101) H01L 2224/11474 (20130101) H01L 2224/11902 (20130101) H01L 2224/13023 (20130101) H01L 2224/13109 (20130101) H01L 2224/16145 (20130101) H01L 2224/16146 (20130101) H01L 2224/17181 (20130101) H01L 2224/32145 (20130101) H01L 2224/48091 (20130101) H01L 2224/48091 (20130101) H01L 2224/48137 (20130101) H01L 2224/48227 (20130101) H01L 2224/73204 (20130101) H01L 2224/73207 (20130101) H01L 2224/80896 (20130101) H01L 2224/81815 (20130101) H01L 2224/81815 (20130101) H01L 2224/92125 (20130101) H01L 2225/0651 (20130101) H01L 2225/06513 (20130101) H01L 2225/06517 (20130101) H01L 2225/06531 (20130101) H01L 2225/06541 (20130101) H01L 2225/06568 (20130101) H01L 2225/06572 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101)
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10121819 — Phototransistor having E-B junction and B-C junction are in direct physical contact and completely encapsulated only by the emitter, the collector and a dielectric

US 10121819	Yao
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of the Navy (DON) United States Marine Corps (USMC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Wavefront Holdings, LLC (Basking Ridge, New Jersey)
ASSIGNEE(S)	WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey)
INVENTOR(S)	Jie Yao (Basking Ridge, New Jersey)
ABSTRACT	Disclosed herein is a phototransistor (PT) comprising an emitter, a collector and a floating base; wherein the floating base, a p-n junction between the emitter and base (E-B junction) and a p-n junction between the base and the collector (B-C junction) are collectively in direct physical contact only with and completely encapsulated only by the emitter, the collector, and a section of a dielectric. Under an operating condition of the PT, a DC current density averaged over the E-B junction or a DC current density averaged over the B-C junction may be at least 100 times of a DC current density averaged over an opto-electronically active region of the PT. A sum of a capacitance of the E-B junction and a capacitance of the B-C junction may be less than 1 fF.
FILED	Thursday, December 08, 2016
APPL NO	15/372950
ART UNIT	2878 — Optics
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14603 (20130101) H01L 27/14681 (20130101) Original (OR) Class H01L 31/1105 (20130101)
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10121932 — Tunable graphene light-emitting device

US 10121932	Torres, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
INVENTOR(S)	Carlos M. Torres, Jr. (San Diego, California); James R. Adleman (San Diego, California); Ryan P. Lu (San Diego, California); Kang L. Wang (Santa Monica, California)
ABSTRACT	A device includes a substrate with a tunnel barrier disposed on active region defined on the substrate, a monolayer of graphene disposed on the tunnel barrier, a dielectric material disposed on the graphene, and an electrode disposed over a region of the dielectric material. A first voltage is applied across the electrode and the graphene to adjust a Fermi level within the graphene to a Fermi level position within the valence band of the graphene based upon a predetermined emission wavelength. A current is injected into the graphene's conduction band to cause the graphene to emit a broadband hot electron luminescence (HEL) spectrum of photons peaked at the predetermined emission wavelength. The device may be configured as a vertical-tunneling light-emitting hot-electron transistor. The broadband HEL photon emission spectrum emanating from the graphene may be voltage-tunable within the electromagnetic spectrum from UV to THz.
FILED	Thursday, November 30, 2017
APPL NO	15/827556
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/34 (20130101) H01L 33/0041 (20130101) Original (OR) Class Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/0842 (20130101)
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10122001 — Polymerized ionic liquid block copolymers as battery membranes

US 10122001	Elabd et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	DREXEL UNIVERSITY (Philadelphia, Pennsylvania); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Yossef A. Elabd (College Station, Texas); Karen I. Winey (Philadelphia, Pennsylvania); Yuesheng Ye (Rockville, Maryland); Jae-Hong Choi (Philadelphia, Pennsylvania); Tsen-Shan Sharon Sharick (Phiadelphia, Pennsylvania)
ABSTRACT	The present invention is directed to lithium ion transport media for use in separators in lithium ion batteries, and the membranes, separators, and devices derived therefrom.
FILED	Friday, October 27, 2017
APPL NO	15/795757
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/00 (20130101) B01J 41/14 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 220/14 (20130101) C08F 220/22 (20130101) C08F 220/22 (20130101) C08F 220/34 (20130101) C08F 220/34 (20130101) C08F 293/005 (20130101) C08F 2438/02 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2231 (20130101) C08J 2353/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/1653 (20130101) Original (OR) Class H01M 8/103 (20130101) H01M 8/1018 (20130101) H01M 8/1027 (20130101) H01M 8/1032 (20130101) H01M 8/1067 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 2008/1095 (20130101) H01M 2300/0082 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Y02E 60/521 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/70 (20130101)
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10122072 — Nanofabric antenna

US 10122072	Zaghloul et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Amir I. Zaghloul (Bethesda, Maryland); Steven D. Keller (Essex, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Amir I. Zaghloul (Bethesda, Maryland); Steven D. Keller (Essex, Maryland)
ABSTRACT	A nanofabric antenna is provided. The nanofabric antenna can include a fabric and a plurality of conductive nanowires extending outwardly from the fabric with the conductive nanowires forming a random array of monopoles. In this manner, an antenna can be included as part of a piece of clothing and/or a piece of fabric used or worn by an individual.
FILED	Thursday, February 09, 2012
APPL NO	13/369334
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Antennas, i.e Radio Aerials H01Q 1/273 (20130101) Original (OR) Class H01Q 21/06 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49016 (20150115)
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10122150 — Nonequilibrium pulsed femtosecond semiconductor disk laser

US 10122150	Kilen et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Arizona Board of Regents on behalf of The University of Arizona (Tucson, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S)	Isak R. Kilen (Tucson, Arizona); Stephan W. Koch (Tucson, Arizona); Jerome V. Moloney (Tucson, Arizona)
ABSTRACT	A surface-emitting semiconductor laser system contains at least one MQW unit of at least three constituent QWs, axially separated from one another substantially non-equidistantly. The MQW unit is located within the axial extent covered, in operation of the laser, by a half-cycle of the standing wave of the field at a wavelength within the gain spectrum of the gain medium; immediately neighboring nodes of the standing wave are on opposite sides of the MQW unit. So-configured MQW unit can be repeated multiple times and/or complemented with individual QWs disposed outside of the half-cycle of the standing wave with which such MQW unit is associated. The semiconductor laser further includes a pump source configured to input energy in the semiconductor gain medium and a mode-locking element to initiate mode-locking.
FILED	Wednesday, November 15, 2017
APPL NO	15/814087
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0604 (20130101) H01S 3/1115 (20130101) H01S 5/34 (20130101) H01S 5/042 (20130101) H01S 5/065 (20130101) Original (OR) Class H01S 5/187 (20130101) H01S 5/0657 (20130101)
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10122350 — Josephson transmission line (JTL) system

US 10122350	Miller et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Donald L. Miller (Export, Pennsylvania); Ofer Naaman (Ellicott City, Maryland)
ASSIGNEE(S)	NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S)	Donald L. Miller (Export, Pennsylvania); Ofer Naaman (Ellicott City, Maryland)
ABSTRACT	One embodiment describes a Josephson transmission line (JTL) system. The system includes a plurality of JTL stages that are arranged in series. The system also includes a clock transformer comprising a primary inductor configured to propagate an AC clock signal and a secondary inductor arranged in a series loop with at least two of the plurality of JTL stages. The clock transformer can be configured to propagate a single flux quantum (SFQ) pulse to set a respective one of the plurality of JTL stages in response to a first phase of the AC clock signal and to reset the respective one of the plurality of JTL stages in response to a second phase of the AC clock signal that is opposite the first phase.
FILED	Tuesday, November 17, 2015
APPL NO	14/943767
ART UNIT	2118 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 1/04 (20130101) Pulse Technique H03K 3/38 (20130101) Original (OR) Class H03K 19/195 (20130101) H03K 19/1952 (20130101)
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10122478 — Methods and devices for real-time monitoring of tunable filters

US 10122478	Khater et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S)	Mohammad Abu Khater (West Lafayette, Indiana); Dimitrios Peroulis (West Lafayette, Indiana)
ABSTRACT	Methods and devices suitable for monitoring the frequency of microwave tunable filters in real time. The frequency readout relies on the natural response of such a filter when excited by a pulse. Methods of measuring an operating frequency of a pole in a tunable filter include measuring a number of cycles in a natural response in the filter when the filter is excited by an electric current pulse, and determining a resonance frequency based on the number of cycles measured in the natural response. Such a method can provide the operating frequency information in a binary digital format, making it relatively easy to read and process. A measuring resonator may be mounted to the filter resonator and connected by a common actuator.
FILED	Monday, February 29, 2016
APPL NO	15/057072
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 1/24 (20130101) G01R 23/02 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/1775 (20130101) H03H 2007/013 (20130101) Pulse Technique H03K 19/21 (20130101) Transmission H04B 17/21 (20150115) Original (OR) Class
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Department of Energy (DOE)

10117431 — Compounds and methods for improving plant performance

US 10117431	Unkefer et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico); University of Maine System Board of Trustees (Bangor, Maine)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico); University of Maine System Board of Trustees (Bangor, Maine)
INVENTOR(S)	Pat J. Unkefer (Los Alamos, New Mexico); Thomas Joseph Knight (, None)
ABSTRACT	The invention is directed to methods and compositions for increasing a growth characteristic of a plant, increasing nutrient use efficiency of a plant, or improving a plant's ability to overcome stress comprising applying a composition comprising ketosuccinamate, a derivative thereof, or a salt thereof, to the plant or to a propagation material of the plant.
FILED	Monday, August 01, 2016
APPL NO	15/225657
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 25/00 (20130101) A01N 37/42 (20130101) Original (OR) Class A01N 37/42 (20130101) A01N 37/42 (20130101) A01N 43/36 (20130101) A01N 43/36 (20130101) A01N 43/36 (20130101) A01N 43/36 (20130101) A01N 43/36 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/40 (20130101) A01N 43/44 (20130101) A01N 43/44 (20130101) A01N 43/44 (20130101) A01N 43/62 (20130101) A01N 43/62 (20130101) A01N 43/62 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/00 (20130101) C05F 11/08 (20130101) Mixtures of Fertilisers Covered Individually by Different Subclasses of Class C05; Mixtures of One or More Fertilisers With Materials Not Having a Specific Fertilising Activity, e.g Pesticides, Soil-conditioners, Wetting Agents; Fertilisers Characterised by Their Form C05G 3/00 (20130101)
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10118124 — Integrated membrane-pyrolysis systems and methods

US 10118124	Hu et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee); ALLIANCE FOR SUSTAINABLE ENERGY, LLC (Golden, Colorado)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee); ALLIANCE FOR SUSTAINABLE ENERGY, LLC (Golden, Colorado)
INVENTOR(S)	Michael Z. Hu (Knoxville, Tennessee); Chaiwat Engtrakul (Louisville, Colorado); Brian L. Bischoff (Knoxville, Tennessee); Mark F. Davis (Broomfield, Colorado)
ABSTRACT	A method of processing a mixture of heated vapors, at least two of which substantially differ in polarity from each other, the method comprising directing said mixture of heated vapors at a temperature of at least 150° C. through a hydrophobic or hydrophilic mesoporous membrane comprising a mesoporous coating of hydrophobized or hydrophilized metal oxide nanoparticles, respectively, wherein the hydrophobic mesoporous membrane permits passage of one or more hydrophobic heated vapors and blocks passage of one or more hydrophilic heated vapors, and wherein the hydrophilic mesoporous membrane permits passage of one or more hydrophilic heated vapors and blocks passage of one or more hydrophobic heated vapors. The method is particularly directed to embodiments where the heated vapors emanate from a pyrolysis process. An apparatus for achieving the above-described method is also described.
FILED	Wednesday, January 25, 2017
APPL NO	15/415370
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) Original (OR) Class B01D 63/063 (20130101) B01D 71/024 (20130101) B01D 2053/221 (20130101) B01D 2255/102 (20130101) B01D 2255/504 (20130101) B01D 2255/2065 (20130101) B01D 2255/20707 (20130101) B01D 2255/20715 (20130101) B01D 2255/20753 (20130101) B01D 2255/20769 (20130101) B01D 2256/24 (20130101) B01D 2257/80 (20130101) B01D 2257/702 (20130101) B01D 2258/0283 (20130101) B01D 2325/36 (20130101) B01D 2325/38 (20130101) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 53/02 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/002 (20130101) C10G 1/02 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 3/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/14 (20130101)
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10118134 — Synthetic membranes and methods of use thereof

US 10118134	Belfort et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S)	Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S)	Georges Belfort (Slingerlands, New York); Joseph Grimaldi (Clifton Park, New York); Joseph Imbrogno (Massapequa, New York); James Kilduff (Saratoga Springs, New York); John Joseph Keating, IV (Troy, New York)
ABSTRACT	The present invention relates to synthetic membranes and use of these synthetic membranes for isolation of volatile organic compounds and purification of water. The synthetic membrane includes a hydrophobic polymer layer located on a polymeric membrane support layer. The invention includes a method of isolating volatile organic compounds with the synthetic membrane by contacting a volatile organic mixture with the hydrophobic polymer layer of the synthetic membrane and removing volatile organic compounds from the polymeric membrane support layer of the synthetic membrane by a process of pervaporation. The invention also includes a method of purifying water with the synthetic membrane by contacting an ionic solution with the hydrophobic polymer layer of the synthetic membrane and removing water from the polymeric membrane support layer of the synthetic membrane by a process of reverse osmosis. The invention also relates to methods of isolating non-polar gases by gas fractionation.
FILED	Friday, May 12, 2017
APPL NO	15/593675
ART UNIT	1671 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 53/228 (20130101) B01D 61/02 (20130101) B01D 61/025 (20130101) B01D 61/362 (20130101) B01D 67/0006 (20130101) B01D 67/0093 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/12 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 71/28 (20130101) B01D 71/40 (20130101) B01D 71/52 (20130101) B01D 71/68 (20130101) B01D 71/78 (20130101) B01D 2257/708 (20130101) B01D 2323/08 (20130101) B01D 2323/34 (20130101) B01D 2323/38 (20130101) B01D 2323/345 (20130101) B01D 2323/385 (20130101) B01D 2325/02 (20130101) B01D 2325/26 (20130101) B01D 2325/38 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/441 (20130101) C02F 2103/08 (20130101) Acyclic or Carbocyclic Compounds C07C 29/86 (20130101) Technologies for Adaptation to Climate Change Y02A 50/235 (20180101)
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10118338 — Additive manufacturing with integrated microliter resin delivery

US 10118338	Deotte et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Joshua R. Deotte (Livermore, California); Xiaoyu Zheng (Livermore, California)
ABSTRACT	An additive manufacturing system utilizing an oxygen-permeable membrane to facilitate low-volume printing and high-speed resin change in a stereolithography-based 3D printer. The membrane is used to constrain the fluid surface at the focal plane of the stereolithography printer and a carrier fluid is used to hold the fluid against the membrane. The small amount of resin is quickly switched using integrated microfluidic channels.
FILED	Wednesday, October 21, 2015
APPL NO	14/919441
ART UNIT	1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/20 (20170801) Original (OR) Class B29C 64/129 (20170801) B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201)
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10118823 — Method of thermally-stabilizing an oxygen transport membrane-based reforming system

US 10118823	Kelly et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Sean M. Kelly (Pittsford, New York); Sadashiv M. Swami (Tonawanda, New York); John D. Peck (West Seneca, New York)
ASSIGNEE(S)	PRAXAIR TECHNOLOGY, INC. (Danbury, Connecticut)
INVENTOR(S)	Sean M. Kelly (Pittsford, New York); Sadashiv M. Swami (Tonawanda, New York); John D. Peck (West Seneca, New York)
ABSTRACT	A method of operating an oxygen transport membrane based reforming system employing one or more packs of thermally coupled panels of reformer tubes and oxygen transport membrane (“OTM”) reactors close to thermo-neutral point is provided. The method produces syngas by converting a hydrocarbon-containing feed, such as natural gas in the reformer tubes of a pack by endothermic steam reforming reactions. The heat required for endothermic reforming reactions is provided by exothermic oxidizing reactions occurring inside the OTM reactors of the pack. At a thermo-neutral point the heat released by exothermic reactions matches the heat required to support endothermic reactions and heat losses in the pack. The method modulates the flow rate of hydrocarbon-containing feed and/or steam-to-carbon ratio of the combined feed to the pack to maintain the surface temperature of oxygen transport membrane reactors below a target maximum temperature. The syngas product oxygen-to-carbon ratio is maintained within a desired target range such that the OTM based reforming system is operated close to thermo-neutral point.
FILED	Tuesday, December 15, 2015
APPL NO	14/969486
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 3/382 (20130101) Original (OR) Class C01B 13/0251 (20130101) C01B 2203/142 (20130101) C01B 2203/0233 (20130101) C01B 2203/0244 (20130101) C01B 2203/0844 (20130101)
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10118862 — Multi-metal oxide ceramic nanomaterial

US 10118862	O'Brien et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S)	Research Foundation of the City University of New York (New York, New York)
INVENTOR(S)	Stephen O'Brien (New York, New York); Shuangyi Liu (New York, New York); Limin Huang (Newark, New Jersey)
ABSTRACT	A convenient and versatile method for preparing complex metal oxides is disclosed. The method uses a low temperature, environmentally friendly gel-collection method to form a single phase nanomaterial. In one embodiment, the nanomaterial consists of Ba_AMn_BTi_CO_Din a controlled stoichiometry.
FILED	Tuesday, March 29, 2016
APPL NO	15/083885
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 1/02 (20130101) C01G 45/12 (20130101) C01G 45/1221 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/85 (20130101) C01P 2006/40 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/462 (20130101) C04B 35/624 (20130101) Original (OR) Class C04B 35/4686 (20130101) C04B 35/6264 (20130101) C04B 35/6325 (20130101) C04B 2235/441 (20130101) C04B 2235/765 (20130101) C04B 2235/3215 (20130101) C04B 2235/3267 (20130101)
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10118877 — Metal-organic frameworks for aromatic hydrocarbon separations

US 10118877	Long et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jeffrey R. Long (Oakland, California); Eric D. Bloch (Cambridge, Massachusetts); Matthew Kapelewski (Berkeley, California); Miguel Carlos I. Gonzalez (Albany, California)
ABSTRACT	The disclosure provides for metal organic frameworks (MOFs) that are selective adsorbents for aromatic hydrocarbons, devices comprising the MOFs thereof, and methods using the MOFS thereof for separating and/or storing aromatic hydrocarbons.
FILED	Wednesday, December 02, 2015
APPL NO	14/957494
ART UNIT	1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Separation B01D 15/08 (20130101) B01D 15/3828 (20130101) B01D 53/02 (20130101) B01D 53/04 (20130101) B01D 53/047 (20130101) B01D 53/0462 (20130101) B01D 2253/204 (20130101) B01D 2257/7027 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Acyclic or Carbocyclic Compounds C07C 7/12 (20130101) Original (OR) Class C07C 7/12 (20130101) C07C 7/12 (20130101) C07C 15/08 (20130101) C07C 15/073 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/065 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 25/003 (20130101)
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10119059 — Thermoelastic cooling

US 10119059	Cui et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Jun Cui (Richland, Washington); Ichiro Takeuchi (Laurel, Maryland); Manfred Wuttig (Silver Spring, Maryland); Yiming Wu (Greenbelt, Maryland); Reinhard Radermacher (Silver Spring, Maryland); Yunho Hwang (Ellicott City, Maryland); Jan Muehlbauer (Bowie, Maryland)
ASSIGNEE(S)	Jun Cui (Ames, Iowa); THE UNIVERSITY OF MARYLAND (College Park, Maryland)
INVENTOR(S)	Jun Cui (Richland, Washington); Ichiro Takeuchi (Laurel, Maryland); Manfred Wuttig (Silver Spring, Maryland); Yiming Wu (Greenbelt, Maryland); Reinhard Radermacher (Silver Spring, Maryland); Yunho Hwang (Ellicott City, Maryland); Jan Muehlbauer (Bowie, Maryland)
ABSTRACT	A cooling system based on thermoelastic effect is provided. The system comprises a heat sink, a refrigerated space and a regenerator coupled to the refrigerated space and to the heat sink to pump heat from the refrigerated space to the heat sink. The regenerator comprises solid thermoelastic refrigerant materials capable of absorbing or releasing heat.
FILED	Tuesday, March 27, 2012
APPL NO	13/431768
ART UNIT	3744 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/00 (20130101)
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10119071 — Enhanced invisible-fluorescent identification tags for materials

US 10119071	Lewis
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Linda A Lewis (Andersonville, Tennessee)
ABSTRACT	A tag composition includes a naphthalocyanine tag component that is invisible in light of the visible spectrum and which emits fluorescent light in a non-visible spectrum under a non-visible excitation energy, a binder for binding the tag to a surface of a material; and a solvent, wherein the tag component and the binder are dissolved in the solvent.
FILED	Friday, January 22, 2016
APPL NO	15/003871
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/06 (20130101) Original (OR) Class C09K 2211/187 (20130101) C09K 2211/188 (20130101) C09K 2211/1022 (20130101) C09K 2211/1074 (20130101)
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10119127 — Nucleic acids encoding plant glutamine phenylpyruvate transaminase (GPT) and uses thereof

US 10119127	Unkefer et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico); UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEES (Bangor, Maine)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico); University of Maine System Board of Trustees (Bangor, Maine)
INVENTOR(S)	Pat J Unkefer (Los Alamos, New Mexico); Penelope S Anderson (Los Alamos, New Mexico); Thomas J Knight (Raymond, Maine)
ABSTRACT	Glutamine phenylpyruvate transaminase (GPT) proteins, nucleic acid molecules encoding GPT proteins, and uses thereof are disclosed. Provided herein are various GPT proteins and GPT gene coding sequences isolated from a number of plant species. As disclosed herein, GPT proteins share remarkable structural similarity within plant species, and are active in catalyzing the synthesis of 2-hydroxy-5-oxoproline (2-oxoglutaramate), a powerful signal metabolite which regulates the function of a large number of genes involved in the photosynthesis apparatus, carbon fixation and nitrogen metabolism.
FILED	Tuesday, March 08, 2016
APPL NO	15/064329
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1096 (20130101) Original (OR) Class C12N 15/827 (20130101) C12N 15/8261 (20130101) C12N 15/8262 (20130101) C12N 15/8269 (20130101) C12N 15/8273 (20130101) Enzymes C12Y 206/01064 (20130101)
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10119197 — Solar water splitting in a molecular photoelectrochemical cell

US 10119197	Alibabaei et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Leila Alibabaei (Carrboro, North Carolina); Matthew Kyle Brennaman (Durham, North Carolina); Michael Norris (Seattle, Washington); Gregory N. Parsons (Raleigh, North Carolina); Thomas J. Meyer (Chapel Hill, North Carolina)
ABSTRACT	A Dye Sensitized Photoelectrosynthesis Cell (DSPEC) splits water with visible light using a derivatized, core/shell nanostructured photoanode with the core having a high surface area conductive metal oxide film—such as nanoITO (indium tin oxide) or nanoATO (antimony tin oxide)—coated with a thin outer shell of, for example, TiO₂formed by Atomic Layer Deposition (ALD). A “chromophore-catalyst assembly” 1, [(PO₃H₂)₂bpy)₂Ru(4-Mebpy-4-bimpy)Ru(tpy)(OH₂)]⁴⁺, which combines both light absorber and water oxidation catalyst in a single molecule, is attached to the TiO₂shell. Visible photolysis of the resulting core/shell/assembly structure with a Pt cathode results in water splitting into hydrogen and oxygen.
FILED	Monday, September 08, 2014
APPL NO	14/479995
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/003 (20130101) C25B 11/0452 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/368 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/135 (20151101)
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10119327 — Method and apparatus for an insulating glazing unit and compliant seal for an insulating glazing unit

US 10119327	Francis, IV et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	ASTRAVAC GLASS, INC. (Colorado Springs, Colorado)
ASSIGNEE(S)	ASTRAVAC GLASS, INC. (Colorado Springs, Colorado)
INVENTOR(S)	William H. Francis, IV (Boulder, Colorado); Gregg E. Freebury (Louisville, Colorado); Neal J. Beidleman (Aspen, Colorado); Michael Hulse (Eerie, Colorado)
ABSTRACT	A Vacuum Insulating Glazing Unit (VIGU) comprises two or more glass lites (panes) spaced apart from one another and hermetically bonded to an edge seal assembly therebetween. The resulting cavity between the lites is evacuated to create at least one insulating vacuum cavity within which are disposed a plurality of stand-off members to maintain separation between the lites. The edge seal assembly is preferably compliant in the longitudinal (i.e., edgewise) direction to allow longitudinal relative motion between the two lites (e.g., from thermal expansion). The longitudinal compliance may be obtained by imprinting a three-dimensional pattern into the edge seal material. The edge seal assembly is preferably bonded to the lites with a first bond portion that is hermetic and a second bond portion that is load-resistant. Methods for producing VIGUs and/or compliant edge seal assemblies and VIGU and edge seal apparatus are disclosed.
FILED	Thursday, April 28, 2016
APPL NO	15/141485
ART UNIT	3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/06 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/06 (20130101) B32B 38/1858 (20130101) B32B 2310/028 (20130101) B32B 2311/00 (20130101) B32B 2315/08 (20130101) Structural Elements; Building Materials E04C 2/34 (20130101) E04C 2/54 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/673 (20130101) Original (OR) Class E06B 3/6612 (20130101) E06B 3/6775 (20130101) E06B 3/66328 (20130101) E06B 3/66357 (20130101) E06B 2003/66395 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 80/24 (20130101)
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10119456 — Ducted combustion systems utilizing flow field preparation

US 10119456	Fitzgerald
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Caterpillar Inc. (Peoria, Illinois)
ASSIGNEE(S)	Caterpillar Inc. (Deerfield, Illinois)
INVENTOR(S)	Russell P. Fitzgerald (Peoria, Illinois)
ABSTRACT	A ducted combustion system includes a combustion chamber and a fuel injector in fluid connection with the combustion chamber, which includes an orifice opening from an injector tip of the fuel injector, the orifice injecting fuel into the combustion chamber as a fuel jet, the fuel jet flowing, within the combustion chamber, in a fuel flow direction. The system includes at least one duct disposed within the combustion chamber, the at least one duct being disposed such that the fuel jet, at least partially, enters one of the at least one ducts upon being injected into the combustion chamber. The at least one duct may be configured for having a flow field air stream within the duct, prior to entrance of the fuel jet, the flow field air stream having a flow direction that is substantially similar to the fuel flow direction.
FILED	Tuesday, January 10, 2017
APPL NO	15/402811
ART UNIT	3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Internal-combustion Piston Engines; Combustion Engines in General F02B 23/00 (20130101) Original (OR) Class Controlling Combustion Engines F02D 41/3005 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/242 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 57/04 (20130101) F02M 61/1806 (20130101)
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10119937 — Method for detecting organophosphorus compounds and illicit drugs

US 10119937	Ewing et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S)	Battelle Memorial Institute (Richland, Washington)
INVENTOR(S)	Robert G. Ewing (Kennewick, Washington); Blandina R. Valenzuela (Richland, Washington); David A. Atkinson (Richland, Washington)
ABSTRACT	A method is disclosed for detecting organophosphorus compounds and illicit drugs using an ion detector. A vapor sample containing at least one analyte and at least one dopant is ionized. A proton-bound adduct ion is formed between the analyte and the dopant in a reaction region defined between the ionization source and the ion detector.
FILED	Friday, July 15, 2016
APPL NO	15/211752
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Original (OR) Class G01N 33/0047 (20130101)
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10120035 — Monitoring and control of electrochemical cell degradation via strain based battery testing

US 10120035	Steiber et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Southwest Research Institute (San Antonio, Texas)
ASSIGNEE(S)	SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas)
INVENTOR(S)	Joe Steiber (Spring Branch, Texas); Jeff Qiang Xu (San Antonio, Texas)
ABSTRACT	A method and system for the monitoring and control of electrochemical cell degradation by use of strain-based battery testing. Strain-based battery is employed to recognize and implement a battery revival cycle to reduce battery degradation rates.
FILED	Tuesday, December 01, 2015
APPL NO	14/956011
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3648 (20130101) G01R 31/3679 (20130101) Original (OR) Class
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10120195 — Multi-aperture optical system for high-resolution imaging

US 10120195	Bossert
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)	National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S)	David Bossert (Albuquerque, New Mexico)
ABSTRACT	Technologies pertaining to a multi-aperture optical imaging system are described herein. The multi-aperture optical system comprises an afocal optical telescope and a plurality of sub-apertures that receive light from the telescope. Each sub-aperture comprises a focusing optic that creates a full-field image onto an individual image sensor that outputs data indicative of an intensity of light received at the sensor. Image processing techniques can be used to combine the sensor outputs for spectral discrimination, to improve dynamic range or to enhance resolution of a scene.
FILED	Tuesday, May 09, 2017
APPL NO	15/590788
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/30 (20130101) G02B 5/045 (20130101) G02B 5/201 (20130101) G02B 5/1819 (20130101) G02B 23/00 (20130101) G02B 23/02 (20130101) G02B 27/106 (20130101) G02B 27/123 (20130101) G02B 27/1066 (20130101) Original (OR) Class G02B 27/4205 (20130101) Pictorial Communication, e.g Television H04N 5/265 (20130101)
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10121642 — Digital electron amplifier with anode readout devices and methods of fabrication

US 10121642	Mane et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Anil U. Mane (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois)
ABSTRACT	Scalable electron amplifier devices and methods of fabricating the devices an atomic layer deposition (“ALD”) fabrication process are described. The ALD fabrication process allows for large area (e.g., eight inches by eight inches) electron amplifier devices to be produced at reduced costs compared to current fabrication processes. The ALD fabrication process allows for nanostructure functional coatings, to impart a desired electrical conductivity and electron emissivity onto low cost borosilicate glass micro-capillary arrays to form the electron amplifier devices.
FILED	Friday, April 13, 2018
APPL NO	15/952973
ART UNIT	2879 — Optics
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 43/246 (20130101) Original (OR) Class
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10121657 — Phosphorus incorporation for n-type doping of diamond with (100) and related surface orientation

US 10121657	Koeck et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S)	Franz A. Koeck (Tempe, Arizona); Srabanti Chowdhury (Chandler, Arizona); Robert J Nemanich (Scottsdale, Arizona)
ABSTRACT	Apparatuses and methods are provided for manufacturing diamond electronic devices. The method includes at least one of the following acts: positioning a substrate in a plasma enhanced chemical vapor deposition (PECVD) reactor; controlling temperature of the substrate by manipulating microwave power, chamber pressure, and gas flow rates of the PECVD reactor; and growing phosphorus doped diamond layer on the substrate using a pulsed deposition comprising a growth cycle and a cooling cycle.
FILED	Tuesday, May 10, 2016
APPL NO	15/151295
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/52 (20130101) C23C 16/274 (20130101) C23C 16/278 (20130101) C23C 16/463 (20130101) C23C 16/511 (20130101) C23C 16/45523 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/16 (20130101) C30B 25/105 (20130101) C30B 29/04 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02527 (20130101) Original (OR) Class H01L 21/02576 (20130101) H01L 29/167 (20130101) H01L 29/868 (20130101) H01L 29/1602 (20130101) H01L 29/6603 (20130101)
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10121910 — Formed photovoltaic module busbars

US 10121910	Rose et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	SunPower Corporation (San Jose, California)
ASSIGNEE(S)	SunPower Corporation (San Jose, California)
INVENTOR(S)	Douglas Rose (Mountain View, California); Shan Daroczi (Santa Clara, California); Thomas Phu (Alameda, California)
ABSTRACT	A photovoltaic system including a cell connection piece coupled to a plurality of photovoltaic cells and a terminal of a junction box. The cell connection piece includes an interconnect bus, a plurality of bus tabs unitarily formed with the interconnect bus, and a terminal bus coupled with the interconnect bus. The plurality of bus tabs extend from the interconnect bus. The terminal bus includes a nonlinear portion.
FILED	Wednesday, October 07, 2015
APPL NO	14/877785
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/05 (20130101) H01L 31/0201 (20130101) Original (OR) Class H01L 31/0465 (20141201) H01L 31/0508 (20130101) H01L 31/02013 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/34 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101)
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10121911 — Photovoltaic device assembly and method

US 10121911	Keenihan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	DOW GLOBAL TECHNOLOGIES LLC (Midland, Michigan)
ASSIGNEE(S)	Dow Global Technologies LLC (Midland, Michigan)
INVENTOR(S)	James R. Keenihan (Midland, Michigan); Joseph A. Langmaid (Caro, Michigan); Robert J. Cleereman (Midland, Michigan); Andrew T. Graham (Midland, Michigan)
ABSTRACT	The present invention is premised upon a connector device and method that can more easily electrically connect a plurality of PV arrays and/or locate these arrays upon a building or structure. It also can optionally provide some additional components (e.g. a bypass diode and/or an indicator means) and can enhance the serviceability of the array.
FILED	Monday, July 13, 2015
APPL NO	14/797857
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/05 (20130101) H01L 31/18 (20130101) H01L 31/048 (20130101) H01L 31/0508 (20130101) H01L 31/02008 (20130101) H01L 31/02008 (20130101) H01L 31/02013 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/79 (20130101) H01R 13/055 (20130101) H01R 13/113 (20130101) H01R 13/639 (20130101) H01R 13/7032 (20130101) H01R 31/00 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/23 (20141201) H02S 20/25 (20141201) H02S 20/25 (20141201) H02S 40/34 (20141201) H02S 40/36 (20141201) Technologies for Adaptation to Climate Change Y02A 30/62 (20180101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 10/12 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115) Y10T 29/49355 (20150115) Y10T 29/49826 (20150115)
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10121925 — Thin film photovoltaic devices with microlens arrays

US 10121925	Xue et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Jiangeng Xue (Gainesville, Florida); Jason David Myers (Gainesville, Florida); Sang-Hyun Eom (Kyunggi-do, South Korea)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	Jiangeng Xue (Gainesville, Florida); Jason David Myers (Gainesville, Florida); Sang-Hyun Eom (Kyunggi-do, South Korea)
ABSTRACT	Textured transparent layers are formed on the incident light receiving surface of thin film solar cells to increase their efficiency by altering the incident light path and capturing a portion of the light reflected at the MLA. The textured transparent layer is an array of lenses of micrometer proportions such as hemispheres, hemi-ellipsoids, partial-spheres, partial-ellipsoids, cones, pyramids, prisms, half cylinders, or combinations thereof. A method of forming the textured transparent layer to the light incident surface of the solar cell is by forming an array of lenses from a photocurable resin and its subsequent curing. The photocurable resin can be applied by inkjet printing or can be applied by roll to roll imprinting or stamping with a mold.
FILED	Friday, June 17, 2011
APPL NO	13/704651
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Optical Elements, Systems, or Apparatus G02B 3/0031 (20130101) G02B 3/0043 (20130101) G02B 5/045 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/054 (20141201) H01L 31/0392 (20130101) H01L 31/0543 (20141201) Original (OR) Class H01L 31/02168 (20130101) H01L 31/02327 (20130101) H01L 31/03921 (20130101) H01L 31/03923 (20130101) H01L 31/03925 (20130101) H01L 51/0036 (20130101) H01L 51/0046 (20130101) H01L 51/0047 (20130101) H01L 51/0078 (20130101) H01L 51/426 (20130101) H01L 51/447 (20130101) H01L 51/4253 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/22 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/541 (20130101) Y02E 10/549 (20130101)
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10121952 — Materials and methods for the preparation of nanocomposites

US 10121952	Talapin et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S)	Dmitri V. Talapin (Riverside, Illinois); Maksym V. Kovalenko (Zurich, Switzerland); Jong-Soo Lee (Chicago, Illinois); Chengyang Jiang (Chicago, Illinois)
ABSTRACT	Disclosed herein is an isolable colloidal particle comprising a nanoparticle and an inorganic capping agent bound to the surface of the nanoparticle, a solution of the same, a method for making the same from a biphasic solvent mixture, and the formation of structures and solids from the isolable colloidal particle. The process can yield photovoltaic cells, piezoelectric crystals, thermoelectric layers, optoelectronic layers, light emitting diodes, ferroelectric layers, thin film transistors, floating gate memory devices, imaging devices, phase change layers, and sensor devices.
FILED	Wednesday, April 20, 2016
APPL NO	15/133494
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) C01B 19/007 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/16 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 5/22 (20130101) C09D 5/24 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/562 (20130101) C09K 11/565 (20130101) C09K 11/883 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/00 (20130101) C30B 29/40 (20130101) C30B 29/46 (20130101) C30B 29/60 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/06 (20130101) H01B 1/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) Original (OR) Class
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10122044 — Semi-solid electrodes with gel polymer additive

US 10122044	Tan et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	24M Technologies, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	24M Technologies, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Taison Tan (Cambridge, Massachusetts); Naoki Ota (Lexington, Massachusetts); Jeffry Disko (North Brookfield, Massachusetts)
ABSTRACT	Embodiments described herein relate generally to electrochemical cells having semi-solid electrodes that include a gel polymer additive such that the electrodes demonstrate longer cycle life while significantly retaining the electronic performance of the electrodes and the electrochemical cells formed therefrom. In some embodiments, a semi-solid electrode can include about 20% to about 75% by volume of an active material, about 0.5% to about 25% by volume of a conductive material, and about 20% to about 70% by volume of an electrolyte. The electrolyte further includes about 0.01% to about 1.5% by weight of a polymer additive. In some embodiments, the electrolyte can include about 0.1% to about 0.7% of the polymer additive.
FILED	Monday, July 21, 2014
APPL NO	14/336119
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/62 (20130101) H01M 4/64 (20130101) H01M 4/624 (20130101) H01M 10/052 (20130101) H01M 10/058 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0085 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49108 (20150115)
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10122046 — Electrolyte compositions for high voltage lithium-ion batteries

US 10122046	Abraham et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Daniel Abraham (Bolingbrook, Illinois); Ye Zhu (San Diego, California)
ABSTRACT	The present invention provides an electrolyte composition for a lithium-ion battery comprising LiPF₆in a liquid carrier comprising a carbonate ester and an unsaturated organoboron compound comprising two or three unsaturated hydrocarbon groups, each unsaturated hydrocarbon group being covalently bonded to a boron atom. The unsaturated hydrocarbon groups are independently selected from vinyl, allyl, propargyl, substituted vinyl, substituted allyl, and substituted propargyl. The substituents of the substituted vinyl, allyl and propargyl groups independently comprise one or more of alkyl and phenyl. The alkyl and phenyl groups optionally can bear one or more substituent selected from halogen (e.g., F), hydroxy, amino, alkoxy, and perfluoroalkoxy.
FILED	Friday, October 03, 2014
APPL NO	14/506316
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0037 (20130101)
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10122102 — X-ray battery adapter system

US 10122102	Garduno et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Gilbert John Garduno (Los Alamos, New Mexico); Orlando Thomas Lopez (Los Alamos, New Mexico); Kyle Matthew Sternberg (Los Alamos, New Mexico)
ABSTRACT	An x-ray battery adapter system may include an x-ray battery adapter and a geometry adapter. The x-ray battery adapter may include a circuit board, a baseplate, a heat sink, a cover, and a battery input. The baseplate may include a connector that connects to an x-ray generating device. The geometry adapter may include a cable, a battery receptacle configured to house a battery, and a voltage sensor and battery connector block assembly. The x-ray battery adapter may allow a user of an x-ray generating device to utilize different power sources.
FILED	Tuesday, April 04, 2017
APPL NO	15/478369
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 11/281 (20130101) Original (OR) Class H01R 13/6666 (20130101) H01R 13/6691 (20130101) H01R 24/54 (20130101)
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10122301 — Pulsed start-up system for electrostatic generators

US 10122301	Post
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Richard F Post (Walnut Creek, California)
ABSTRACT	A new rotor start-up system is provided for application to rotating systems such as stationary or vehicular electromechanical battery systems. An embodiment of the system consists of a “locator” that includes a stationary permanent-magnet pole above which is a circular ferromagnetic (e.g., iron) strip embedded in the lower, inner edge of the flywheel rotor. The lower edge of this strip is wave-like so that the magnet can pull the rotor around to a position where the position relative to the minimum capacity between the rotor and stator electrodes is such as to launch the rotor in a chosen direction, i.e., either clock-wise or counter-clockwise. Startup from rest is then accomplished by applying a short high-voltage ac or dc pulse to the EMB capacitor.
FILED	Monday, February 29, 2016
APPL NO	15/056155
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) Original (OR) Class
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10122365 — System and method for flexure based microstructural logic gates

US 10122365	Pascall et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Andrew J. Pascall (Livermore, California); Robert Matthew Panas (Dublin, California)
ABSTRACT	A resettable mechanical logic circuit is disclosed which is formed as part of a material structure. The circuit makes use of a bistable element. The bistable element may have a characteristic of being stable in either one of first and second orientations, once moved past a midpoint between the first and second orientations.
FILED	Tuesday, February 28, 2017
APPL NO	15/445038
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 19/20 (20130101) Original (OR) Class
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10122412 — Power line communication system and method of auto-commissioning system nodes

US 10122412	Scott et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	ABL IP Holding, LLC (Conyers, Georgia)
ASSIGNEE(S)	ABL IP Holding, LLC (Conyers, Georgia)
INVENTOR(S)	Jeffrey Michael Scott (San Pablo, California); Michael Miu (Castro Valley, California)
ABSTRACT	A power line communication system and method permit auto-commissioning of multiple device control modules on a DC power line during the power up of the system. Device control modules associated with the peripheral devices are powered up sequentially and a unique address is assigned to each device controller when it is powered up. The device control modules have a unique circuit configuration that allows the use of inexpensive and mostly passive components. The cost effectiveness of the device controller design becomes particularly significant in applications, such as multi-panel OLED lighting fixtures, with high node counts.
FILED	Tuesday, January 30, 2018
APPL NO	15/883678
ART UNIT	2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Transmission H04B 3/58 (20130101) H04B 3/542 (20130101) Original (OR) Class H04B 3/546 (20130101) H04B 3/548 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/0803 (20130101)
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10122741 — Non-harmful insertion of data mimicking computer network attacks

US 10122741	Neil et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Joshua Neil (Jemez Springs, New Mexico); Alexander Kent (Los Alamos, New Mexico); Curtis Hash, Jr. (Santa Fe, New Mexico); Michael Fisk (Los Alamos, New Mexico); Alexander Brugh (Los Alamos, New Mexico); Curtis Storlie (Jemez Springs, New Mexico); Benjamin Uphoff (Los Alamos, New Mexico)
ABSTRACT	Non-harmful data mimicking computer network attacks may be inserted in a computer network. Anomalous real network connections may be generated between a plurality of computing systems in the network. Data mimicking an attack may also be generated. The generated data may be transmitted between the plurality of computing systems using the real network connections and measured to determine whether an attack is detected.
FILED	Thursday, May 26, 2016
APPL NO	15/165036
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/577 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 7/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/002 (20130101) H04L 63/1408 (20130101) H04L 63/1416 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 63/1433 (20130101) H04L 2463/144 (20130101)
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10123380 — Instantaneous in-line heating of samples on a monolithic microwave integrated circuit microfluidic device

US 10123380	Beer et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Neil Reginald Beer (Pleasanton, California); Benjamin Fasenfest (Fremont, California); John Chang (Danville, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Neil Reginald Beer (Pleasanton, California); Benjamin Fasenfest (Fremont, California); John Chang (Danville, California)
ABSTRACT	A micro-electro-mechanical system for heating a sample including a substrate, a micro-channel flow channel in the substrate, a carrier fluid within the micro-channel flow channel for moving the sample in the micro-channel flow channel, and a microwave source that directs microwaves onto the sample in the micro-channel flow channel for heating the sample. The carrier fluid and the substrate are made of materials that are not appreciably heated by the microwaves. The microwave source includes conductive traces or strips and a microwave power source connected to the conductive traces or strips.
FILED	Thursday, April 30, 2009
APPL NO	12/433721
ART UNIT	3742 — Cryptography and Security
CURRENT CPC	Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/806 (20130101) Original (OR) Class
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RE047115 — Composition and method for delivery of BMP-2 amplifier/co-activator for enhancement of osteogenesis

US RE47115	Zamora et al.
FUNDED BY	Department of Energy (DOE) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	Ferring B.V. (Hoofddorp, Netherlands); Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S)	Ferring B.V. (, Netherlands); Brookhaven Science Associates, LLC (, None)
INVENTOR(S)	Paul O. Zamora (Gaithersburg, Maryland); Brent Lee Atkinson (Highlands Ranch, Colorado); Xinhua Lin (Plainview, New York); Louis A. Pena (Poquott, New York)
ABSTRACT	A composition comprising a synthetic growth factor analog comprising a non-growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analog is attached to and can be released from the osteoconductive material and is an amplifier/co-activator of osteoinduction.
FILED	Friday, August 05, 2016
APPL NO	15/230189
ART UNIT	3991 — Central Reexamination Unit (Chemical)
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1875 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/12 (20130101) A61L 27/24 (20130101) A61L 27/227 (20130101) A61L 2430/02 (20130101) Peptides C07K 14/4705 (20130101) Original (OR) Class
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National Science Foundation (NSF)

10117436 — Antimicrobial polymeric compositions

US 10117436	Wynne et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Virginia Commonwealth University (Richmond, Virginia)
ASSIGNEE(S)	VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia)
INVENTOR(S)	Kenneth J. Wynne (Midlothian, Virginia); Souvik Chakrabarty (Ithaca, New York); Wei Zhang (Midlothian, Virginia); Asima Chakravorty (Richmond, Virginia); Olufemi O. Oyesanya (Chesapeake, Virginia)
ABSTRACT	A compound having the formula: wherein n, y, R₁and R₂are defined herein, and others, methods of making of and using, and compositions made thereby which have an antimicrobial resistance effect are described.
FILED	Thursday, March 24, 2016
APPL NO	15/080567
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 55/00 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/184 (20130101) C07F 7/1804 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/61 (20130101) C08G 18/718 (20130101) C08G 18/758 (20130101) C08G 18/4862 (20130101) C08G 18/5066 (20130101) C08G 18/6674 (20130101) C08G 65/18 (20130101) C08G 65/22 (20130101) C08G 65/226 (20130101) C08G 65/336 (20130101) C08G 2650/04 (20130101) C08G 2650/38 (20130101) C08G 2650/48 (20130101) C08G 2650/50 (20130101) C08G 2650/64 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/04 (20130101)
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10117629 — High energy grating techniques

US 10117629	Butler et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S)	Leslie G. Butler (Baton Rouge, Louisiana); Kyungmin Ham (Baton Rouge, Louisiana); Warren W. Johnson (Baton Rouge, Louisiana)
ABSTRACT	Imaging techniques that may be used in applications such as differential phase contrast imaging are disclosed that include, for example, configuring a beam source and a beam detector such that a beam connects the two, positioning an object, a phase grating and an analyzer grating in the beam path, producing multiple data sets based on various analyzer grating positions, and conducting a regression analysis using a predetermined function having a set of fitting coefficients to establish those fitting coefficients. In those techniques, the fitting coefficients may be used to characterize a set of interference properties associated with the object.
FILED	Thursday, December 03, 2015
APPL NO	14/958882
ART UNIT	2884 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/484 (20130101) Original (OR) Class A61B 6/4291 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) G01N 23/20075 (20130101) G01N 2223/401 (20130101)
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10117840 — Sulfur(VI) fluoride compounds and methods for the preparation thereof

US 10117840	Dong et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Jiajia Dong (Shanghai, China PRC); K. Barry Sharpless (La Jolla, California); Jeffery W. Kelly (La Jolla, California); Wentao Chen (Walnut Creek, California)
ABSTRACT	This application describes a compound represented by Formula (I): (I) wherein: Y is a biologically active organic core group comprising one or more of an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group, to which Z is covalently bonded; n is 1, 2, 3, 4 or 5; m is 1 or 2; Z is O, NR, or N; X¹is a covalent bond or —CH₂CH₂—, X²is O or NR; and R comprises H or a substituted or unsubstituted group selected from an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group. Methods of preparing the compounds, methods of using the compounds, and pharmaceutical compositions comprising the compounds are described as well.
FILED	Friday, June 05, 2015
APPL NO	15/316742
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 31/14 (20130101) A61K 31/40 (20130101) A61K 31/47 (20130101) A61K 31/53 (20130101) A61K 31/56 (20130101) A61K 31/65 (20130101) A61K 31/70 (20130101) A61K 31/136 (20130101) A61K 31/197 (20130101) A61K 31/198 (20130101) A61K 31/397 (20130101) A61K 31/407 (20130101) A61K 31/439 (20130101) A61K 31/473 (20130101) A61K 31/485 (20130101) A61K 31/505 (20130101) A61K 31/515 (20130101) A61K 31/655 (20130101) A61K 31/4045 (20130101) A61K 31/4168 (20130101) A61K 31/4245 (20130101) A61K 31/4353 (20130101) A61K 31/4709 (20130101) A61K 31/4745 (20130101) A61K 31/5513 (20130101) A61K 31/7048 (20130101) A61K 38/31 (20130101) A61K 47/54 (20170801) A61K 47/48023 (20130101) A61K 51/0497 (20130101) Acyclic or Carbocyclic Compounds C07C 305/26 (20130101) C07C 2601/14 (20170501) C07C 2603/18 (20170501) Heterocyclic Compounds C07D 277/82 (20130101) C07D 295/26 (20130101) C07D 295/088 (20130101) C07D 295/185 (20130101) Peptides C07K 1/02 (20130101) C07K 1/1136 (20130101) C07K 2/00 (20130101)
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10117907 — Glycosylated PACAP/VIP analogues with enhanced CNS penetration for treatment of neurodegenerative diseases

US 10117907	Polt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of the University of Arizona, a body corporate (Tucson, Arizona)
INVENTOR(S)	Robin Polt (Tucson, Arizona); Torsten A E Falk (Tucson, Arizona)
ABSTRACT	A glycosylated pleiotropic peptide pituitary adenylate cyclase-activating polypeptide (PACAP) which can both agonize PAC₁receptors, causing neuroprotective effects, and antagonize VPAC receptors, causing anti-inflammation in several models of acute neuronal damage and neurodegenerative diseases, including ALS, PD, migraines, and certain forms of dementia, is described. Also described is a method of relieving symptoms of ALS, PD, migraines, and certain forms of dementia, comprising administering to a subject in need thereof an effective amount of a glycosylated PACAP.
FILED	Tuesday, February 16, 2016
APPL NO	15/044924
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class A61K 38/2278 (20130101) Peptides C07K 2317/21 (20130101) C07K 2317/41 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2800/2814 (20130101) G01N 2800/2821 (20130101)
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10117935 — Adsorption of fluorinated anesthetics within the pores of molecular crystals

US 10117935	Miljanic et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	University of Houston System (Houston, Texas)
ASSIGNEE(S)	UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S)	Ognjen Miljanic (Houston, Texas); Teng-Hao Chen (Houston, Texas); Watchareeya Kaveevivitchai (Houston, Texas)
ABSTRACT	A method of delivering or sequestering anesthetic agents by adsorption of such agents by porous partially fluorinated compounds which display high weight adsorption capacities.
FILED	Thursday, December 10, 2015
APPL NO	15/534923
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 47/22 (20130101) Original (OR) Class Separation B01D 53/02 (20130101) B01D 2253/20 (20130101) B01D 2257/2066 (20130101) B01D 2259/4533 (20130101) Heterocyclic Compounds C07D 231/16 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/154 (20151101)
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10117937 — Highly branched alpha-D-glucans

US 10117937	Yao et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana); PHYTOPTION, LLC. (West Lafayette, Indiana)
INVENTOR(S)	Yuan Yao (West Lafayette, Indiana); Jingmin Zhang (West Lafayette, Indiana)
ABSTRACT	Compositions including a highly branched alpha-D-glucan or modified forms thereof and a solute compound are described herein. The compositions can provide increased water solubility and/or increased rate of dissolution for the solute compound. The compositions can also provide increased stability for the solute compound. Methods for preparing and using compositions including a solute compound and a highly branched alpha-D-glucan are also described.
FILED	Friday, April 19, 2013
APPL NO	14/395200
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/73 (20130101) A61K 31/192 (20130101) A61K 31/343 (20130101) A61K 47/36 (20130101) Original (OR) Class A61K 2800/49 (20130101) A61K 2800/544 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0009 (20130101)
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10117968 — Method of printing a tissue construct with embedded vasculature

US 10117968	Lewis et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President And Fellows Of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Jennifer A. Lewis (Cambridge, Massachusetts); David B. Kolesky (Cambridge, Massachusetts); Mark A. Skylar-Scott (Brookline, Massachusetts); Kimberly A. Homan (Somerville, Massachusetts); Ryan L. Truby (Boston, Massachusetts); Amelia Sydney Gladman (Cambridge, Massachusetts)
ABSTRACT	A printed tissue construct comprises one or more tissue patterns, where each tissue pattern comprises a plurality of viable cells of one or more predetermined cell types. A network of vascular channels interpenetrates the one or more tissue patterns. An extracellular matrix composition at least partially surrounds the one or more tissue patterns and the network of vascular channels. A method of printing a tissue construct with embedded vasculature comprises depositing one or more cell-laden filaments, each comprising a plurality of viable cells, on a substrate to form one or more tissue patterns. Each of the one or more tissue patterns comprises one or more predetermined cell types. One or more sacrificial filaments, each comprising a fugitive ink, are deposited on the substrate to form a vascular pattern interpenetrating the one or more tissue patterns. The vascular pattern and the one or more tissue patterns are at least partially surrounded with an extracellular matrix composition. The fugitive ink is then removed to create vascular channels in the extracellular matrix composition, thereby forming an interpenetrating vascular network in a tissue construct.
FILED	Tuesday, November 04, 2014
APPL NO	15/146613
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) A61F 2/105 (20130101) A61F 2240/002 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/222 (20130101) A61L 27/225 (20130101) A61L 27/507 (20130101) Original (OR) Class A61L 27/3633 (20130101) A61L 27/3808 (20130101) A61L 27/3813 (20130101) A61L 27/3826 (20130101) A61L 2430/34 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/40 (20170801) B29C 64/106 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Apparatus for Enzymology or Microbiology; C12M 33/00 (20130101)
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10118119 — Radio frequency process sensing, control, and diagnostics network and system

US 10118119	Sappok et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	CTS Corporation (Lisle, Illinois)
ASSIGNEE(S)	CTS Corporation (Lisle, Illinois)
INVENTOR(S)	Alexander G. Sappok (Cambridge, Massachusetts); Paul A. Ragaller (Dorchester, Massachusetts); Leslie Bromberg (Sharon, Massachusetts); Andrew D. Herman (Granger, Indiana)
ABSTRACT	A radio frequency sensing, control, and particulate matter diagnostics network and system and method and, more specifically, a radio frequency particulate filter diagnostics system comprising a housing including an inlet connected to a source of particulate matter, a particulate filter in the housing and adapted for filtering the particulate matter, and a radio frequency sensor adapted to detect conditions of abnormal particulate filter or system operation and including at least one radio frequency probe configured to be in contact with the housing for the particulate filter housing and adapted to receive radio frequency signals and a radio frequency control unit in communication with the radio frequency probe.
FILED	Thursday, March 16, 2017
APPL NO	15/461128
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Separation B01D 46/0086 (20130101) Original (OR) Class B01D 2279/30 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/021 (20130101) F01N 9/002 (20130101) F01N 11/00 (20130101) F01N 11/005 (20130101) F01N 2550/04 (20130101) F01N 2550/24 (20130101) F01N 2560/12 (20130101) F01N 2900/08 (20130101) F01N 2900/0416 (20130101) F01N 2900/0418 (20130101) F01N 2900/1602 (20130101) F01N 2900/1606 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101)
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10118169 — Chiral ligand-based metal-organic frameworks for broad-scope asymmetric catalysis

US 10118169	Lin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	The University of Chicago (Chicago, Illinois); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Wenbin Lin (Chicago, Illinois); Joseph M. Falkowski (Annandale, New Jersey); Takahiro Sawano (Chicago, Illinois)
ABSTRACT	Metal-organic framework (MOFs) compositions based on chiral phosphine-, chiral oxazoline-, chiral pyridine-, and chiral diene-derived organic bridging ligands were synthesized and then post-synthetically metalated with metal precursors such as Ru and Rh complexes. The metal complexes could also be directly incorporated into the MOFs. The MOFs provide a versatile family of recyclable and reusable single-site solid catalysts for catalyzing a variety of asymmetric organic transformations, including the addition of arylboronic acids to α,β-unsaturated ketones and alkimines, the hydrogenation of substituted alkene and carbonyl compounds, and cyclization reactions. The solid catalysts can also be integrated into a flow reactor or a supercritical fluid reactor.
FILED	Monday, March 30, 2015
APPL NO	15/129851
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1691 (20130101) Original (OR) Class B01J 31/1805 (20130101) B01J 31/2409 (20130101) B01J 31/2447 (20130101) B01J 2531/0263 (20130101) B01J 2531/0266 (20130101) B01J 2531/822 (20130101) Acyclic or Carbocyclic Compounds C07C 29/44 (20130101) C07C 41/09 (20130101) C07C 45/69 (20130101) C07C 67/303 (20130101) C07C 227/04 (20130101) C07C 231/02 (20130101) C07C 2102/44 (20130101) Heterocyclic Compounds C07D 307/93 (20130101)
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10118175 — Method and system for coordination on optically controlled microfluidic systems

US 10118175	Akella et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Srinivas Akella (Charlotte, North Carolina); Zhiqiang Ma (Charlotte, North Carolina)
ASSIGNEE(S)
INVENTOR(S)	Srinivas Akella (Charlotte, North Carolina); Zhiqiang Ma (Charlotte, North Carolina)
ABSTRACT	In accordance with one embodiment, a method for automatically coordinating droplets, beads, nanostructures, and/or biological objects for optically controlled microfluidic systems, comprising using light to move one or a plurality of droplets or the like simultaneously, applying an algorithm to coordinate droplet and/or other motions and avoid undesired droplet and/or other collisions, and moving droplets and/or others to a layout of droplets and/or others. In another embodiment, a system for automatically coordinating droplets and/or others for optically controlled microfluidic systems, comprising using a light source to move one or a plurality of droplets and/or others simultaneously, using an algorithm to coordinate droplet and/or other motions and avoid undesired droplet and/or other collisions, and using a microfluidic device to move droplets and/or others to a layout of droplets and/or others.
FILED	Friday, October 06, 2017
APPL NO	15/726996
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502792 (20130101) Original (OR) Class B01L 2300/089 (20130101) B01L 2300/0816 (20130101) B01L 2300/0819 (20130101) B01L 2400/0427 (20130101) B01L 2400/0454 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 19/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/2191 (20150401)
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10118833 — Dimensionally focused nanoparticle synthesis methodology

US 10118833	Robinson et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Cornell University (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Richard D. Robinson (Ithaca, New York); Tobias Hanrath (Ithaca, New York); Curtis Williamson (Ithaca, New York); Douglas Nevers (Ithaca, New York)
ABSTRACT	A methodology for synthesizing a nanoparticle batch, such as but not limited to a metal chalcogenide nanoparticle batch and further such as but not limited to a metal sulfide nanoparticle batch is predicated upon an expectation and observation that at elevated concentrations of at least one reactant material within a heat-up nanoparticle batch synthesis method, the resulting nucleated batch comprises nanoparticles that may be dimensionally focused to provide a substantially monodisperse nanoparticle batch. The embodied methodology is also applicable to a continuous reactor. The embodied methodology also considers viscosity as a dimensionally focusing result effective variable.
FILED	Friday, October 02, 2015
APPL NO	15/516131
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 3/12 (20130101) Original (OR) Class C01G 11/02 (20130101) C01G 21/21 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/88 (20130101) C01P 2004/04 (20130101) C01P 2004/51 (20130101) C01P 2004/64 (20130101) C01P 2006/22 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/95 (20130101) Y10S 977/773 (20130101) Y10S 977/824 (20130101) Y10S 977/825 (20130101) Y10S 977/896 (20130101)
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10118853 — Systems and methods for producing robust chalcogenide optical fibers

US 10118853	Abouraddy et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
ASSIGNEE(S)	UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
INVENTOR(S)	Ayman F. Abouraddy (Winter Park, Florida); Guangming Tao (Orlando, Florida); Soroush Shabahang (Orlando, Florida)
ABSTRACT	In one embodiment, a chalcogenide glass optical fiber is produced by forming a billet including a chalcogenide glass mass and a polymer mass in a stacked configuration, heating the billet to a temperature below the melting point of the chalcogenide glass, extruding the billet in the ambient environment to form a preform rod having a chalcogenide glass core and a polymer jacket, and drawing the preform rod.
FILED	Thursday, June 09, 2016
APPL NO	15/177894
ART UNIT	2883 — Optics
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 6/0273 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 37/026 (20130101) C03B 37/027 (20130101) C03B 37/01205 (20130101) C03B 37/01274 (20130101) Original (OR) Class C03B 2201/86 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) C03C 4/10 (20130101) C03C 13/043 (20130101) C03C 25/18 (20130101) C03C 25/106 (20130101) C03C 2204/00 (20130101) C03C 2213/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/00 (20130101) G02B 1/10 (20130101) G02B 6/036 (20130101) G02B 6/02395 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/239 (20150115) Y10T 428/24612 (20150115) Y10T 428/31533 (20150401)
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10118976 — Anion-coordinating polymer electrolytes and related compositions, methods and systems

US 10118976	Savoie et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S)	Brett M. Savoie (Pasadena, California); Michael A. Webb (Pasadena, California); Robert H. Grubbs (South Pasadena, California); Thomas F. Miller, III (South Pasadena, California); Geoffrey W. Coates (Lansing, New York); Qi Zheng (Ithaca, New York)
ABSTRACT	Anion-coordinating polymers comprising one or more anion-coordinating unit of Formula (I), optionally in combination with one or more cation-coordinating unit of Formula (II) and/or a linking unit of Formula (III) and related electrolytes, batteries, methods and system.
FILED	Wednesday, January 04, 2017
APPL NO	15/398682
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 30/06 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/328 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/10 (20130101) C08K 3/38 (20130101) C08K 2003/0812 (20130101) Compositions of Macromolecular Compounds C08L 43/00 (20130101) C08L 79/00 (20130101) C08L 81/02 (20130101) C08L 85/00 (20130101) C08L 85/04 (20130101) C08L 87/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0565 (20130101)
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10119035 — Abhesive coatings

US 10119035	Wynne et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Kenneth J. Wynne (Midlothian, Virginia); Wei Zhang (Henrico, Virginia); Chenyu Wang (Richmond, Virginia); Souvik Chakrabarty (Richmond, Virginia)
ASSIGNEE(S)	VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia)
INVENTOR(S)	Kenneth J. Wynne (Midlothian, Virginia); Wei Zhang (Henrico, Virginia); Chenyu Wang (Richmond, Virginia); Souvik Chakrabarty (Richmond, Virginia)
ABSTRACT	A monolithic, self-stratifying polymer coating, comprising: inner and outer-most surfaces on opposite sides of the coating, the inner surface being in contact with and adhered to an article; a surface region, extending from the outermost surface to a depth of about 2 nm from the outermost surface; a middle region, extending from a depth of about 2 nm from the outermost surface to a depth of less than about 2000 nm from the outermost surface; and a bulk region, extending from a depth of less than about 2000 nm from the outermost surface to the inner surface; wherein the surface region comprises a fluorous polyoxetane having the formula: (I) wherein n is an integer of 0-1 1, and m is an integer>0, in a greater concentration relative to the middle and bulk regions; wherein the middle region comprises 3F-SiO_1.5groups in a greater concentration relative to the surface and bulk regions; and wherein the bulk region comprises a polyurethane in a greater concentration relative to the surface and middle regions.
FILED	Thursday, July 26, 2012
APPL NO	14/235447
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/718 (20130101) C08G 18/758 (20130101) C08G 18/5015 (20130101) C08G 18/6674 (20130101) C08G 65/18 (20130101) C08G 65/226 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1662 (20130101) Original (OR) Class C09D 175/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1393 (20150115) Y10T 428/31551 (20150401)
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10119059 — Thermoelastic cooling

US 10119059	Cui et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Jun Cui (Richland, Washington); Ichiro Takeuchi (Laurel, Maryland); Manfred Wuttig (Silver Spring, Maryland); Yiming Wu (Greenbelt, Maryland); Reinhard Radermacher (Silver Spring, Maryland); Yunho Hwang (Ellicott City, Maryland); Jan Muehlbauer (Bowie, Maryland)
ASSIGNEE(S)	Jun Cui (Ames, Iowa); THE UNIVERSITY OF MARYLAND (College Park, Maryland)
INVENTOR(S)	Jun Cui (Richland, Washington); Ichiro Takeuchi (Laurel, Maryland); Manfred Wuttig (Silver Spring, Maryland); Yiming Wu (Greenbelt, Maryland); Reinhard Radermacher (Silver Spring, Maryland); Yunho Hwang (Ellicott City, Maryland); Jan Muehlbauer (Bowie, Maryland)
ABSTRACT	A cooling system based on thermoelastic effect is provided. The system comprises a heat sink, a refrigerated space and a regenerator coupled to the refrigerated space and to the heat sink to pump heat from the refrigerated space to the heat sink. The regenerator comprises solid thermoelastic refrigerant materials capable of absorbing or releasing heat.
FILED	Tuesday, March 27, 2012
APPL NO	13/431768
ART UNIT	3744 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/00 (20130101)
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10119148 — RNAs from pathogens inhibit plant immunity

US 10119148	Jin
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Organismal Systems (IOS) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Hailing Jin (Riverside, California)
ABSTRACT	The present invention relates to pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a polynucleotide that is complementary to, or mediates destruction, of a plant immunity suppressing sRNA of a pathogen, wherein the plant is less susceptible to the pathogen compared to a control plant lacking the expression cassette. Methods of making and cultivating pathogen-resistant plants are also provided.
FILED	Thursday, October 02, 2014
APPL NO	14/505378
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8282 (20130101) Original (OR) Class
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10119151 — Methods and devices for charged molecule manipulation

US 10119151	Aten et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Brigham Young University (Provo, Utah)
ASSIGNEE(S)	Brigham Young University (Provo, Utah)
INVENTOR(S)	Quentin T. Aten (Orem, Utah); Larry L. Howell (Orem, Utah); Brian D. Jensen (Orem, Utah); Sandra Burnett (Saratoga Springs, Utah)
ABSTRACT	Systems and methods for manipulating molecular material are provided. In one aspect, for example, a method for manipulating molecular material may include positioning an uncharged needle structure in electrical proximity with a charged molecular material at a first locus in a liquid environment, charging the needle structure such that at least a portion of the charged molecular material becomes associated with the needle structure, moving the needle structure and the first locus relative to one another, and discharging the needle structure to disassociate the charged molecular material at a second locus.
FILED	Wednesday, December 11, 2013
APPL NO	14/103618
ART UNIT	1799 — Plants
CURRENT CPC	Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/89 (20130101) Original (OR) Class
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10119202 — Method for preparing electro-mechanically stretched hydrogel micro fibers

US 10119202	Mao et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Hai-Quan Mao (Baltimore, Maryland); Shuming Zhang (Lehigh Acres, Florida); Xi Liu (Suzhou, China PRC); Brian Patrick Ginn (Baltimore, Maryland)
ABSTRACT	The presently disclosed subject matter provides a scalable and electrostretching approach for generating microfibers exhibiting uniaxial alignment from polymer solutions. Such microfibers can be generated from a variety of natural polymers or synthetic polymers. The hydrogel microfibers can be used for controlled release of bioactive agents. The internal uniaxial alignment exhibited by the presently disclosed fibers provides improved mechanical properties to microfibers, contact guidance cues and induces alignment for cells seeded on or within the microfibers.
FILED	Tuesday, April 30, 2013
APPL NO	14/398072
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2430/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Original (OR) Class D01D 5/06 (20130101) D01D 5/12 (20130101) D01D 5/0046 (20130101) D01D 5/0076 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 2/00 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/001 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2201/01 (20130101) D10B 2211/01 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/298 (20150115) Y10T 428/2967 (20150115)
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10119758 — Drying using phase change material (PCM)

US 10119758	Yagoobi et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Worcester Polytechnic Institute (Worcester, Massachusetts)
ASSIGNEE(S)	Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S)	Jamal Yagoobi (Hopkinton, Massachusetts); Yasmin Khakpour (Worcester, Massachusetts)
ABSTRACT	Drying a planar substrate such as paper sheet goods for packing materials includes layering a phase change material (PCM) on a substrate, in which the substrate has a moisture content and adapted for moisture removal to form a planar medium. A drying process disposes the substrate adjacent to a plurality of rollers and heat the layered substrate to a predetermined temperature based on a specific heat of the PCM. The rollers advance the layered substrate in series through pocket ventilation regions between the heat transfer elements, such that the pocket ventilation regions permit drying of the substrate enhanced by the specific heat of the temperature sensitive material. Upon drying, the layered substrate forms the planar medium suitable for use as a packing medium or other suitable application. The pocket ventilation regions are based on the PCM to facilitate drying and eradication of moisture from the paper planar substrate.
FILED	Monday, June 01, 2015
APPL NO	14/726803
ART UNIT	3743 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/18 (20130101) Original (OR) Class F26B 13/26 (20130101)
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10119900 — In-line particle characterization

US 10119900	Wang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	New York University (New York, New York)
ASSIGNEE(S)	NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S)	Chen Wang (Jersey City, New Jersey); Hagay Shpaisman (Kedium, Israel); Andrew Hollingsworth (Princeton, New Jersey); David G. Grier (New York, New York)
ABSTRACT	Holographic video microscopy yields fast and accurate measurements of the size and refractive index of individual colloidal particles. Particle-resolved characterization offers useful insights into the progress of colloidal synthesis without relying on models for the distributions of particle sizes and properties, and can be performed rapidly enough to provide feedback for process control. The measured increase in the most probable radius over the course of the reaction is consistent with the LaMer model for colloidal growth. Uniformity in the measured refractive index suggests that the spheres grow with uniform density. The joint distribution of size and refractive index provides evidence for a low rate of nucleation proceeding after the initial nucleation event. The same analysis reveals that these PDMS particles shrink by compactification in the first few days after their synthesis.
FILED	Wednesday, June 24, 2015
APPL NO	15/320646
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0211 (20130101) G01N 15/1463 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/0004 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/08 (20130101) G03H 1/0443 (20130101) G03H 2001/005 (20130101) G03H 2001/0033 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/52 (20130101) G06K 9/00147 (20130101) G06K 9/4661 (20130101) G06K 9/6212 (20130101) G06K 2209/40 (20130101)
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10119958 — Arrays and methods for guided cell patterning

US 10119958	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	University of Washington (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Miqin Zhang (Bothell, Washington); Mandana Veiseh (Emeryville, California)
ABSTRACT	Guided cell patterning arrays for single cell patterning are disclosed. The arrays include a plurality of cell adhesion sites that are individually isolated on an inert surface. Each cell adhesion site has one or more cell adhesion peptides having affinity to a cell surface receptor. The inert surface is resistant to cell adhesion.
FILED	Tuesday, August 25, 2015
APPL NO	14/835224
ART UNIT	1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 20/02 (20130101) C40B 40/02 (20130101) C40B 60/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/5008 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02164 (20130101)
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10119960 — Method of screening cancer cells using wrinkle patterns on a thin membrane

US 10119960	Chae et al.
FUNDED BY	Department of Veterans Affairs (DVA) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona); The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The U.S. Government represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S)	Junseok Chae (Scottsdale, Arizona); Jennie Appel (Tempe, Arizona); Joseph Liao (Stanford, California)
ABSTRACT	Systems and methods for performing cancer screening assays are disclosed. The disclosed systems and methods use a thin film comprising cross-linked polysiloxane. At least a portion of a biological sample to be assayed is contacted with the thin film, along with a cell culture media. After a subsequent incubation period, the thin film is visualized to detect a wrinkle pattern (or lack thereof). The presence of one or more wrinkles and/or a higher degree of wrinkling in the thin film indicates the presence of cancer cells in the biological sample. The disclosed systems and methods can be incorporated into improved assays and kits for cancer screening.
FILED	Tuesday, June 09, 2015
APPL NO	15/316710
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8422 (20130101) G01N 33/487 (20130101) G01N 33/574 (20130101) G01N 33/5091 (20130101) Original (OR) Class
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10120263 — Low-duty-cycle continuous-wave photoconductive terahertz imaging and spectroscopy systems

US 10120263	Jarrahi
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Mona Jarrahi (Los Angeles, California)
ABSTRACT	Systems and methods for plasmonics enhanced photomixing for generating continuous-wave (CW) frequency-tunable terahertz radiation in accordance with embodiments of the invention are disclosed. A photomixing system configured to generate continuous-wave terahertz frequency signals can include an optical pump configured to generate at least two beams, where the at least two beams are utilized to create a frequency-offset and operate below a 50% duty cycle, where the duty cycle includes an operation cycle and a sleep cycle. The photomixing system can also include a photomixer that includes a radiating element configured to receive the frequency-offset and to generate a terahertz radiation utilizing the received frequency-offset and the radiating element, where the radiating element includes at least one plasmonic contact electrode.
FILED	Friday, June 12, 2015
APPL NO	15/318347
ART UNIT	2874 — Optics
CURRENT CPC	Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3534 (20130101) Original (OR) Class G02F 2203/13 (20130101)
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10120447 — Haptic display with simultaneous sensing and actuation

US 10120447	Peshkin et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Michael A. Peshkin (Evanston, Illinois); James E. Colgate (Evanston, Illinois)
ABSTRACT	Touch interface devices having systems and methods for producing multi-point haptics utilizing simultaneous sensing and actuation are disclosed. In a first configuration, two layers of electrodes are used, including a top layer for haptics near a touch surface of an insulating substrate and a bottom layer for sensing at the bottom surface of the insulating substrate, with the two electrode sets have substantially the same pattern as one another. In a second configuration, a single array of electrodes is used near a touch surface of an insulating substrate and serves as both surface haptic devices and sensing devices.
FILED	Tuesday, June 17, 2014
APPL NO	14/306842
ART UNIT	2621 — Selective Visual Display Systems
CURRENT CPC	Electric Digital Data Processing G06F 3/016 (20130101) Original (OR) Class G06F 3/044 (20130101) G06F 3/0416 (20130101) G06F 2203/04111 (20130101)
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10121245 — Identification of inflammation in tissue images

US 10121245	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	UNIVERSITY OF NOTRE DAME (South Bend, Indiana); UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	UNIVERSITY OF NOTRE DAME (South Bend, Indiana)
INVENTOR(S)	Danny Ziyi Chen (Granger, Indiana); Jiazhuo Wang (Sunnyvale, California); John DeWolfe MacKenzie (San Francisco, California); Rageshree Ramachandran (San Francisco, California)
ABSTRACT	Systems and methods are provided for identifying markers for inflammation in a tissue image. The tissue image is captured as an image of a histology slide. Subcellular structures in the tissue image are segmented via a first automated process to identify at least one variety of immune cells within the image. Glands and vilii are identified within the tissue image via a second automated process. Neutrophils are identified within the tissue image via a third automated process. An output representing the identified glands, villi, neutrophils, and other immune cells is provided to a human operator.
FILED	Wednesday, September 14, 2016
APPL NO	15/264836
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/48 (20130101) G06K 9/00147 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/12 (20170101) G06T 7/162 (20170101) G06T 2207/10024 (20130101) G06T 2207/10056 (20130101) G06T 2207/30024 (20130101)
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10121388 — Methods, systems, and apparatuses to convey chorded input

US 10121388	Seim et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Caitlyn Seim (Atlanta, Georgia); Thad Eugene Starner (Atlanta, Georgia)
ABSTRACT	Disclosed herein are methods, systems, computer readable media, and apparatuses for conveying chorded input to a user. Chorded input can be conveyed by one or more sequences of stimulation events, wherein each sequence represents a particular chorded input.
FILED	Wednesday, April 29, 2015
APPL NO	14/700102
ART UNIT	3715 — Amusement and Education Devices
CURRENT CPC	Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 15/00 (20130101) G09B 19/00 (20130101) Original (OR) Class G09B 21/00 (20130101) G09B 21/001 (20130101) G09B 21/003 (20130101)
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10121925 — Thin film photovoltaic devices with microlens arrays

US 10121925	Xue et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Jiangeng Xue (Gainesville, Florida); Jason David Myers (Gainesville, Florida); Sang-Hyun Eom (Kyunggi-do, South Korea)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	Jiangeng Xue (Gainesville, Florida); Jason David Myers (Gainesville, Florida); Sang-Hyun Eom (Kyunggi-do, South Korea)
ABSTRACT	Textured transparent layers are formed on the incident light receiving surface of thin film solar cells to increase their efficiency by altering the incident light path and capturing a portion of the light reflected at the MLA. The textured transparent layer is an array of lenses of micrometer proportions such as hemispheres, hemi-ellipsoids, partial-spheres, partial-ellipsoids, cones, pyramids, prisms, half cylinders, or combinations thereof. A method of forming the textured transparent layer to the light incident surface of the solar cell is by forming an array of lenses from a photocurable resin and its subsequent curing. The photocurable resin can be applied by inkjet printing or can be applied by roll to roll imprinting or stamping with a mold.
FILED	Friday, June 17, 2011
APPL NO	13/704651
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Optical Elements, Systems, or Apparatus G02B 3/0031 (20130101) G02B 3/0043 (20130101) G02B 5/045 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/054 (20141201) H01L 31/0392 (20130101) H01L 31/0543 (20141201) Original (OR) Class H01L 31/02168 (20130101) H01L 31/02327 (20130101) H01L 31/03921 (20130101) H01L 31/03923 (20130101) H01L 31/03925 (20130101) H01L 51/0036 (20130101) H01L 51/0046 (20130101) H01L 51/0047 (20130101) H01L 51/0078 (20130101) H01L 51/426 (20130101) H01L 51/447 (20130101) H01L 51/4253 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/22 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/541 (20130101) Y02E 10/549 (20130101)
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10121952 — Materials and methods for the preparation of nanocomposites

US 10121952	Talapin et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S)	THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S)	Dmitri V. Talapin (Riverside, Illinois); Maksym V. Kovalenko (Zurich, Switzerland); Jong-Soo Lee (Chicago, Illinois); Chengyang Jiang (Chicago, Illinois)
ABSTRACT	Disclosed herein is an isolable colloidal particle comprising a nanoparticle and an inorganic capping agent bound to the surface of the nanoparticle, a solution of the same, a method for making the same from a biphasic solvent mixture, and the formation of structures and solids from the isolable colloidal particle. The process can yield photovoltaic cells, piezoelectric crystals, thermoelectric layers, optoelectronic layers, light emitting diodes, ferroelectric layers, thin film transistors, floating gate memory devices, imaging devices, phase change layers, and sensor devices.
FILED	Wednesday, April 20, 2016
APPL NO	15/133494
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) C01B 19/007 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/72 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/16 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 5/22 (20130101) C09D 5/24 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/562 (20130101) C09K 11/565 (20130101) C09K 11/883 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/00 (20130101) C30B 29/40 (20130101) C30B 29/46 (20130101) C30B 29/60 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/06 (20130101) H01B 1/10 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) Original (OR) Class
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10122396 — Circuits and methods for detecting interferers

US 10122396	Kinget et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Peter R. Kinget (Summit, New Jersey); John Wright (New York, New York); Rabia Tugce Yazicigil (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Peter R. Kinget (Summit, New Jersey); John Wright (New York, New York); Rabia Tugce Yazicigil (New York, New York)
ABSTRACT	Mechanisms for interferer detection can detect interferers by detecting elevated signal amplitudes in one or more of a plurality of bins (or bands) in a frequency range between a maximum frequency (f_MAX) and a minimum frequency (f_MIN). To perform rapid interferer detection, the mechanisms downconvert an input signal x(t) with a local oscillator (LO) to a complex baseband signal xI(t)+jxQ(t). xI(t) and xQ(t) are then multiplied by m unique pseudorandom noise (PN) sequences (e.g., Gold sequences) gm(t) to produce m branch signals for I and m branch signals for Q. The branch signals are then low pass filtered, converted from analog to digital form, and pairwise combined by a pairwise complex combiner. Finally, a support recovery function is used to identify interferers.
FILED	Monday, September 14, 2015
APPL NO	15/510910
ART UNIT	2632 — Digital Communications
CURRENT CPC	Demodulation or Transference of Modulation From One Carrier to Another H03D 7/161 (20130101) Amplifiers H03F 3/19 (20130101) H03F 2200/294 (20130101) H03F 2200/451 (20130101) Transmission H04B 1/0017 (20130101) H04B 1/1027 (20130101) H04B 1/1036 (20130101) Original (OR) Class H04B 17/345 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/22 (20130101)
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Department of Agriculture (USDA)

10117447 — Extrusion of high density hydroxypropylmethylcellulose edible flexible gels

US 10117447	Chiou et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); DOW Global Technologies LLC (Midland, Michigan)
ASSIGNEE(S)	The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia); Dow Global Technologies LLC (Albany, California)
INVENTOR(S)	Bor-Sen Chiou (Albany, California); Syed H Imam (Walnut Creek, California); Wallace H Yokoyama (Davis, California); Stephanie K Lynch (Springfield, Missouri)
ABSTRACT	A method for and product of the low temperature extrusion of food grade HPMC by sequential addition of powdered HPMC with or without starch is disclosed herein.
FILED	Monday, March 17, 2014
APPL NO	14/216551
ART UNIT	1792 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 1/0534 (20130101) Original (OR) Class Shaping or Working of Foodstuffs, Not Fully Covered by a Single Other Subclass A23P 1/12 (20130101) Polysaccharides; Derivatives Thereof C08B 11/00 (20130101) C08B 15/00 (20130101) C08B 31/00 (20130101)
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10119027 — Compositions including lignin

US 10119027	Chen-Sarkanen et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S)	REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S)	Yi-ru Chen-Sarkanen (New Brighton, Minnesota); Simo Sarkanen (New Brighton, Minnesota); Yun-Yan Wang (Saint Paul, Minnesota)
ABSTRACT	Disclosed herein are compositions that include at least about 75 weight percent (wt %) alkylated lignin based on the total weight of the composition without any solvent(s). The material having a tensile strength of at least about 35 MPa, an elongation-to-break of at least about 1.5%, or both. Articles including such materials and methods of forming the same are also disclosed.
FILED	Friday, March 13, 2015
APPL NO	15/125380
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Derivatives of Natural Macromolecular Compounds C08H 6/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/07 (20130101) C08K 5/136 (20130101) Compositions of Macromolecular Compounds C08L 97/005 (20130101) Original (OR) Class
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10119115 — Methods and compositions for producing solvents

US 10119115	Blaschek et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); Eastman Renewable Materials, LLC (Kingsport, Tennessee)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois); Eastman Renewable Materials, LLC (Kingsport, Tennessee)
INVENTOR(S)	Hans P. Blaschek (Champaign, Illinois); Steven F. Stoddard (Cerro Gordo, Illinois); Zhen Shi (Champaign, Illinois)
ABSTRACT	Described herein are methods, compositions and synthetic biology approaches for solvent production, including but not limited to butanol production. Described herein are recombinant bacteria and yeast strains which may be used in production of a solvent, including but not limited to butanol, from lignocellulosic and other plant-based feedstocks. Described herein are methods of producing solvents, including but not limited to butanol, using bacteria and yeast strains. Described herein are methods of producing organisms that display highly efficient butanol production.
FILED	Friday, July 10, 2015
APPL NO	14/796253
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/1217 (20130101) C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/16 (20130101) C12P 7/28 (20130101) C12P 7/065 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/145 (20130101) Enzymes C12Y 101/01001 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Y02E 50/17 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

PP029787 — Blueberry plant named ‘Echo’

US PP29787	Finn
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Chad E. Finn (Corvallis, Oregon)
ABSTRACT	‘Echo’ is a new and distinct repeat flowering, ornamental blueberry (Vaccinium section Cyanococcus L.) cultivar that originated from seed produced from the cross of the female blueberry plant ‘Perpetua’ (U.S. Plant Pat. No. 24,209) and the male blueberry plant ORUS 55-1 (unpatented). ‘Echo’ is a blueberry clone distinguished by its ornamental characteristics that include a spreading bush habit with glossy leaves, repeat flowering and fruiting, and small, mild flavored dark blue fruit.
FILED	Tuesday, March 28, 2017
APPL NO	15/530947
ART UNIT	1661 — Plants
CURRENT CPC	New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/368 (20180501) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

National Aeronautics and Space Administration (NASA)

10119084 — Associative polymers to control formation of particulate matter from ignitable compositions and related compositions, methods and systems

US 10119084	Kornfield et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL) Federally Funded Research and Development Center (FFRDC) Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Julia A. Kornfield (Pasadena, California); Ming-Hsin Wei (Pasadena, California)
ABSTRACT	Described herein are associative polymers capable of controlling formation of particulate matter from a non-polar ignitable composition upon ignition of the non-polar ignitable composition, alone or in combination with control of a physical and/or chemical property of the non-polar compositions and related compositions, methods and systems. Associative polymers herein described have a non-polar backbone and functional groups presented at ends of the non-polar backbone, with a number of the functional groups presented at the ends of the non-polar backbone formed by associative functional groups capable of undergoing an associative interaction with another associative functional group with an association constant (k) such that the strength of each associative interaction is less than the strength of a covalent bond between atoms and in particular less than the strength of a covalent bond between backbone atoms.
FILED	Monday, September 19, 2016
APPL NO	15/269911
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 136/06 (20130101) C08F 2810/40 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/195 (20130101) Original (OR) Class C10L 10/02 (20130101) C10L 10/08 (20130101) C10L 2200/043 (20130101) C10L 2200/0423 (20130101) C10L 2200/0446 (20130101) C10L 2250/04 (20130101) C10L 2270/04 (20130101) C10L 2270/10 (20130101) C10L 2270/023 (20130101) C10L 2270/026 (20130101) C10L 2290/24 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10119525 — Alpha-stream convertor

US 10119525	Dyson et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator (Washington, District of Columbia)
INVENTOR(S)	Rodger W. Dyson (Elyria, Ohio); Geoffrey A. Bruder (Parma Heights, Ohio)
ABSTRACT	A thermo-acoustic engine and/or cooler is provided and includes an elongated tubular body, multiple regenerators disposed within the body, multiple heat exchangers disposed within the body, where at least one heat exchanger is disposed adjacent to each of the multiple regenerators, multiple transducers axially disposed at each end of the body, and an acoustic wave source generating acoustic waves. At least one of the acoustic waves is amplified by one of the regenerators and at least another acoustic wave is amplified by a second one of regenerators.
FILED	Friday, May 22, 2015
APPL NO	14/719885
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/00 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10121030 — Frequency multiplexed radio frequency identification

US 10121030	Fink et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Patrick W. Fink (Missouri City, Texas); Gregory Y. Lin (Friendswood, Texas); Timothy F. Kennedy (Sugar Land, Texas); Phong H. Ngo (Friendswood, Texas); Lucas S. Kinion (Houston, Texas)
ABSTRACT	A radio frequency identification (RFID) system for frequency multiplexing includes, in one exemplary embodiment, and RFID interrogator configured for generating an RFID signal, wherein a channel frequency of the RFID signal changes over time; a first narrow band antenna, characterized by a first passband, the first passband corresponding to a first range of frequencies; a second narrow band antenna, characterized by a second passband, the second passband corresponding to a second range of frequencies, wherein the second range of frequencies differs from the first range of frequencies, whereby the second passband differs from the first passband; and first and second feed lines configured for feeding the RFID signal to each of the first and second narrow band antennas, respectively. Other embodiments include systems and methods including similar and different RFID components and aspects for frequency multiplexing.
FILED	Wednesday, June 28, 2017
APPL NO	15/635704
ART UNIT	2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10356 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

10122363 — Current source logic gate

US 10122363	Krasowski et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America, as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of National Aeronautics and Space Administraion (Washington, District of Columbia)
INVENTOR(S)	Michael J. Krasowski (Chagrin Falls, Ohio); Norman F. Prokop (Shaker Heights, Ohio); Philip G. Neudeck (Olmsted Township, Ohio)
ABSTRACT	A current source logic gate with depletion mode field effect transistor (“FET”) transistors and resistors may include a current source, a current steering switch input stage, and a resistor divider level shifting output stage. The current source may include a transistor and a current source resistor. The current steering switch input stage may include a transistor to steer current to set an output stage bias point depending on an input logic signal state. The resistor divider level shifting output stage may include a first resistor and a second resistor to set the output stage point and produce valid output logic signal states. The transistor of the current steering switch input stage may function as a switch to provide at least two operating points.
FILED	Monday, August 14, 2017
APPL NO	15/676223
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 19/20 (20130101) H03K 19/09403 (20130101) H03K 19/09432 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

10121055 — Method and system for facial landmark localization

US 10121055	Savvides et al.
FUNDED BY	Department of Transportation (USDOT) Federal Highway Administration (FHWA) Exploratory Advanced Research Program (EARP) National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S)	Marios Savvides (Wexford, Pennsylvania); Keshav Thirumalai Seshadri (Pittsburgh, Pennsylvania)
ABSTRACT	This invention describes methods and systems for the automated facial landmark localization. Our approach proceeds from sparse to dense landmarking steps using a set of models to best account for the shape and texture variation manifested by facial landmarks across pose and expression. We also describe the use of an l_1-regularized least squares approach that we incorporate into our shape model, which is an improvement over the shape model used by several prior Active Shape Model (ASM) based facial landmark localization algorithms.
FILED	Thursday, September 08, 2016
APPL NO	15/259143
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/66 (20130101) G06K 9/00248 (20130101) Original (OR) Class G06K 9/3216 (20130101) G06K 9/6277 (20130101) G06K 2009/3225 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10121212 — System and method for transportation demand management

US 10121212	Barbeau et al.
FUNDED BY	Department of Transportation (USDOT) U.S. State Government State of Florida Florida Department of Transportation (FDOT)
APPLICANT(S)	Sean J. Barbeau (Tampa, Florida); Edgar Banguero (Seattle, Washington); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Kevin Kerrigan (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Sean J. Barbeau (Tampa, Florida); Edgar Banguero (Seattle, Washington); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Kevin Kerrigan (Tampa, Florida)
ABSTRACT	Accuracy of data collected from comprehensive travel surveys is a key to studying and analyzing human travel behavior. Better understanding of travel behavior enhances the ability of transportation professionals to utilize resources available in designing appropriate solutions to existing problems. In the past, this data has been obtained through paper or phone-based surveys of individuals and households. These surveys are subject to problems, including inaccurate data due to user error, apathy, and intentional or unintentional omissions, and must often be limited to one or two days due to the amount of effort required from the participant. The present invention describes a system and method that improves both quality and quantity of data gathered on individual travel behavior across multiple modes of transportation, including non-motorized travel, and submits the data from any location. By combining Personal Digital Assistants (PDAs) and Global Positioning System (GPS) devices the proposed system automates the collection of much of the data needed to measure individual travel behavior.
FILED	Friday, June 10, 2016
APPL NO	15/179541
ART UNIT	3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Electric Digital Data Processing G06F 3/0481 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/02 (20130101) G06Q 50/14 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

10119960 — Method of screening cancer cells using wrinkle patterns on a thin membrane

US 10119960	Chae et al.
FUNDED BY	Department of Veterans Affairs (DVA) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona); The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The U.S. Government represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S)	Junseok Chae (Scottsdale, Arizona); Jennie Appel (Tempe, Arizona); Joseph Liao (Stanford, California)
ABSTRACT	Systems and methods for performing cancer screening assays are disclosed. The disclosed systems and methods use a thin film comprising cross-linked polysiloxane. At least a portion of a biological sample to be assayed is contacted with the thin film, along with a cell culture media. After a subsequent incubation period, the thin film is visualized to detect a wrinkle pattern (or lack thereof). The presence of one or more wrinkles and/or a higher degree of wrinkling in the thin film indicates the presence of cancer cells in the biological sample. The disclosed systems and methods can be incorporated into improved assays and kits for cancer screening.
FILED	Tuesday, June 09, 2015
APPL NO	15/316710
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8422 (20130101) G01N 33/487 (20130101) G01N 33/574 (20130101) G01N 33/5091 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

10121819 — Phototransistor having E-B junction and B-C junction are in direct physical contact and completely encapsulated only by the emitter, the collector and a dielectric

US 10121819	Yao
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of the Navy (DON) United States Marine Corps (USMC) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Wavefront Holdings, LLC (Basking Ridge, New Jersey)
ASSIGNEE(S)	WAVEFRONT HOLDINGS, LLC (Basking Ridge, New Jersey)
INVENTOR(S)	Jie Yao (Basking Ridge, New Jersey)
ABSTRACT	Disclosed herein is a phototransistor (PT) comprising an emitter, a collector and a floating base; wherein the floating base, a p-n junction between the emitter and base (E-B junction) and a p-n junction between the base and the collector (B-C junction) are collectively in direct physical contact only with and completely encapsulated only by the emitter, the collector, and a section of a dielectric. Under an operating condition of the PT, a DC current density averaged over the E-B junction or a DC current density averaged over the B-C junction may be at least 100 times of a DC current density averaged over an opto-electronically active region of the PT. A sum of a capacitance of the E-B junction and a capacitance of the B-C junction may be less than 1 fF.
FILED	Thursday, December 08, 2016
APPL NO	15/372950
ART UNIT	2878 — Optics
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14603 (20130101) H01L 27/14681 (20130101) Original (OR) Class H01L 31/1105 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

10121212 — System and method for transportation demand management

US 10121212	Barbeau et al.
FUNDED BY	Department of Transportation (USDOT) U.S. State Government State of Florida Florida Department of Transportation (FDOT)
APPLICANT(S)	Sean J. Barbeau (Tampa, Florida); Edgar Banguero (Seattle, Washington); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Kevin Kerrigan (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Sean J. Barbeau (Tampa, Florida); Edgar Banguero (Seattle, Washington); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Kevin Kerrigan (Tampa, Florida)
ABSTRACT	Accuracy of data collected from comprehensive travel surveys is a key to studying and analyzing human travel behavior. Better understanding of travel behavior enhances the ability of transportation professionals to utilize resources available in designing appropriate solutions to existing problems. In the past, this data has been obtained through paper or phone-based surveys of individuals and households. These surveys are subject to problems, including inaccurate data due to user error, apathy, and intentional or unintentional omissions, and must often be limited to one or two days due to the amount of effort required from the participant. The present invention describes a system and method that improves both quality and quantity of data gathered on individual travel behavior across multiple modes of transportation, including non-motorized travel, and submits the data from any location. By combining Personal Digital Assistants (PDAs) and Global Positioning System (GPS) devices the proposed system automates the collection of much of the data needed to measure individual travel behavior.
FILED	Friday, June 10, 2016
APPL NO	15/179541
ART UNIT	3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Electric Digital Data Processing G06F 3/0481 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/02 (20130101) G06Q 50/14 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

10119559 — Fail-safe hydraulic actuator with constant force retraction springs

US 10119559	Powers et al.
FUNDED BY
APPLICANT(S)	LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
ASSIGNEE(S)	Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S)	Joseph H. Powers (Bethesda, Maryland); Barry L. West (Bethesda, Maryland)
ABSTRACT	A fail-safe hydraulic actuator that uses one or more constant force retraction springs to provide fail-safe retraction of the piston and piston rod in the event of loss of hydraulic pressure. The constant force retraction spring(s) can be packaged in a small volume thus decreasing the overall length of the actuator. This allows the actuator to be utilized in areas where length is a concern. The constant force retraction spring(s) are part of constant force retraction spring mechanism(s) that can be mounted within a hydraulic fluid cavity of the fail-safe hydraulic actuator to protect the constant force retraction spring mechanism(s) from the environment surrounding the actuator. A sensor that detects the linear position of the piston within the piston chamber may also be provided.
FILED	Thursday, March 09, 2017
APPL NO	15/454745
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/1476 (20130101) Original (OR) Class F15B 15/2861 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10119913 — Die-integrated aspheric mirror

US 10119913	Goeders et al.
FUNDED BY
APPLICANT(S)	Honeywell International Inc. (Morris Plains, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morris Plains, New Jersey)
INVENTOR(S)	James Edward Goeders (Plymouth, Minnesota); Matthew Edward Lewis Jungwirth (Golden Valley, Minnesota); Terry Dean Stark (St. Louis Park, Minnesota)
ABSTRACT	Apparatuses and systems for a die-integrated aspheric mirror are described herein. One apparatus includes an ion trap die including a number of ion locations and an aspheric mirror integrated with the ion trap die.
FILED	Monday, August 28, 2017
APPL NO	15/687688
ART UNIT	2884 — Optics
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6404 (20130101) G01N 21/6456 (20130101) Original (OR) Class G01N 2021/6469 (20130101) G01N 2021/6484 (20130101) Optical Elements, Systems, or Apparatus G02B 5/10 (20130101) G02B 17/0605 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 3/16 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

10122170 — Load adjustment sharing system and method

US 10122170	Wen et al.
FUNDED BY
APPLICANT(S)	Yao-Jung Wen (Albany, California); William Woody Delp (Oakland, California)
ASSIGNEE(S)	PHILIPS LIGHTING HOLDING B.V. (Eindhoven, Netherlands)
INVENTOR(S)	Yao-Jung Wen (Albany, California); William Woody Delp (Oakland, California)
ABSTRACT	A method (3000) of load adjustment sharing for a space (100) including a first zone (110) and a second zone (120), and a control unit (10) for a load adjustment sharing system (1) are provided. The method comprises the steps of receiving (301) information (130) related to a load adjustment for the space, and receiving (302) environment information (113) about the first zone and environment information (123) about the second zone. Further, based on the environment information about the first zone, the environment information about the second zone and the information related to the load adjustment for the space, a load adjustment share (114) for the first zone and a load adjustment share (124) for the second zone are determined. The present invention may be utilized in buildings including a plurality of zones. The present invention is advantageous in that the load adjustment sharing is intelligently adapted to the environment circumstances in the different zones.
FILED	Thursday, March 22, 2012
APPL NO	14/008398
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/14 (20130101) Original (OR) Class H02J 2003/007 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 70/3225 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/76 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 20/222 (20130101) Y04S 40/22 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/469 (20150401)
VIEW PATENT	@ USPTO: Full Text PDF

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THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 06, 2018.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

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Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

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A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

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