FedInvent™ Patents
Patent Details for Tuesday, November 20, 2018
This page was updated on Monday, March 27, 2023 at 05:40 AM GMT
Department of Health and Human Services (HHS)
US 10130288 | Klueh et al. |
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FUNDED BY |
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APPLICANT(S) | Cell and Molecular Tissue Engineering, LLC (Avon, Connecticut) |
ASSIGNEE(S) | Cell and Molecular Tissue Engineering, LLC (Avon, Connecticut) |
INVENTOR(S) | Ulrike W. Klueh (Detroit, Michigan); Donald L. Kreutzer (Avon, Connecticut) |
ABSTRACT | Disclosed herein are sensors with a layer of dehydrated modified basement membrane preparation formed thereon. The basement membrane has been modified before dehydration of remove low molecular weight components. In some embodiments, the basement membrane is crosslinked. Methods of making and using the products also are disclosed. |
FILED | Tuesday, October 11, 2016 |
APPL NO | 15/290139 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1495 (20130101) A61B 5/14503 (20130101) Original (OR) Class A61B 5/14532 (20130101) A61B 2562/02 (20130101) A61B 2562/12 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1866 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/08 (20130101) A61L 31/14 (20130101) A61L 31/145 (20130101) A61L 2400/18 (20130101) A61L 2420/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130309 | Gore et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | Amit Satish Gore (Glenville, New York); Jeffrey Michael Ashe (Gloversville, New York) |
ABSTRACT | A system and method for determining physiological parameters based on electrical impedance measurements is provided. One method includes obtaining electrical measurement signals acquired from a plurality of transducers coupled to a surface of an object and spatially pre-conditioning the obtained electrical measurement signals. The method also includes performing multiple-input-multiple-output (MIMO) processing of the spatially pre-conditioned electrical measurement signals to correlate the spatially pre-conditioned electrical measurement signals to separate the electrical measurement signals. |
FILED | Tuesday, August 23, 2016 |
APPL NO | 15/244014 |
ART UNIT | 2864 — Printing/Measuring and Testing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/11 (20130101) A61B 5/113 (20130101) A61B 5/0402 (20130101) A61B 5/0531 (20130101) A61B 5/0816 (20130101) A61B 5/7207 (20130101) A61B 5/7225 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) A61B 5/7282 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130415 | Webster et al. |
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APPLICANT(S) | John G. Webster (Madison, Wisconsin); Dieter Haemmerich (Charleston, South Carolina); James Arthur Will (Columbus, Wisconsin); David Mahvi (Middleton, Wisconsin); Ann O'Rourke (Madison, Wisconsin); David James Schutt (Charleston, South Carolina) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | John G. Webster (Madison, Wisconsin); Dieter Haemmerich (Charleston, South Carolina); James Arthur Will (Columbus, Wisconsin); David Mahvi (Middleton, Wisconsin); Ann O'Rourke (Madison, Wisconsin); David James Schutt (Charleston, South Carolina) |
ABSTRACT | An electrode array supports multiple electrodes and energizes them so that adjacent electrodes do not have the same polarity. In one embodiment, the electrodes are held about a circumference outside and surrounding a tumor and opposed electrodes are energized in a round robin fashion to promote current flow through the center of the tumor from a variety of angles. |
FILED | Monday, February 25, 2008 |
APPL NO | 12/072208 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/1477 (20130101) Original (OR) Class A61B 2017/00017 (20130101) A61B 2017/00022 (20130101) A61B 2017/00026 (20130101) A61B 2018/0075 (20130101) A61B 2018/124 (20130101) A61B 2018/143 (20130101) A61B 2018/00654 (20130101) A61B 2018/00726 (20130101) A61B 2018/00755 (20130101) A61B 2018/00791 (20130101) A61B 2018/00797 (20130101) A61B 2018/00827 (20130101) A61B 2018/00875 (20130101) A61B 2018/1432 (20130101) A61B 2018/1467 (20130101) A61B 2560/0418 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130513 | Peli et al. |
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APPLICANT(S) | SCHEPENS EYE RESEARCH INSTITUTE (Boston, Massachusetts) |
ASSIGNEE(S) | Schepens Eye Research Institute (Boston, Massachusetts) |
INVENTOR(S) | Eliezer Peli (Boston, Massachusetts); Jae-Hyun Jung (Boston, Massachusetts) |
ABSTRACT | The disclosure features systems for providing information to a user about the user's environment, the system featuring a detection apparatus configured to obtain image information about the environment, where the image information corresponds to information at multiple distances relative to a position of the user within the environment, and an electronic processor configured to obtain focal plane distance information defining a set of one or more distance values relative to the position of the user within the environment, construct one or more confocal images of the environment, from the image information and the set of one or more distance values, wherein each of the one or more confocal images corresponds to a different distance value and comprises a set of pixels, and transform the one or more confocal images to form one or more representative images comprising fewer pixels and a lower dynamic range. |
FILED | Thursday, March 19, 2015 |
APPL NO | 15/126775 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/08 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/36046 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130560 | Clarkson et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Brian H. Clarkson (Ann Arbor, Michigan); Timothy F. Scott (Ann Arbor, Michigan) |
ABSTRACT | Provided herein are composite materials comprising a thiol-ene polymer resin in a continuous phase and a filler in a discontinuous phase, the filler comprising fluorapatite crystals and silica. Further provided are methods of using these composite materials as restoratives in dental applications. This dental composite is labeled as “smart” because, when the shrinkage stress of the composite is greater than a programmable or pre-selected threshold level, it will elicit visual clues for the dentist. |
FILED | Friday, March 20, 2015 |
APPL NO | 15/127041 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/0017 (20130101) Original (OR) Class A61K 6/0023 (20130101) A61K 6/0073 (20130101) A61K 6/083 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/38 (20130101) C08F 2/48 (20130101) C08F 2222/102 (20130101) C08F 2222/1013 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130590 | Frank et al. |
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APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | David Frank (Lexington, Massachusetts); Michael Xiang (Boston, Massachusetts) |
ABSTRACT | Described herein are, inter alia, methods for decreasing the growth of a cancer cell, the method comprising delivering to a target cancer cell a growth-inhibitory amount of an atovaquone-related compound, wherein, prior to the delivery, an increased level of activation of the mTOR pathway in the cancer compared to a control level of activation of the mTOR pathway has been found. Also provided are methods for determining the susceptibility of cancer to treatment with an atovaquone-related compound and for assessing the success of therapy with such a compound. |
FILED | Tuesday, September 30, 2014 |
APPL NO | 15/025934 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) Original (OR) Class A61K 31/122 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5017 (20130101) G01N 33/57496 (20130101) G01N 2800/52 (20130101) G01N 2800/7028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130593 | Wainer et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Irving William Wainer (Washington, District of Columbia); Michel Bernier (Pikesville, Maryland); Rajib Kumar Paul (Baltimore, Maryland) |
ABSTRACT | This disclosure concerns the discovery of the use of fenoterol analogs for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analog to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity. |
FILED | Monday, August 01, 2016 |
APPL NO | 15/225643 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130594 | Wainer et al. |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); SRI International (Menlo Park, California) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); SRI International (Menlo Park, California) |
INVENTOR(S) | Irving W. Wainer (Washington, District of Columbia); Michel Bernier (Pikesville, Maryland); Lawrence Robert Toll (Redwood City, California); Lucita Arenas Jimenez (Menlo Park, California) |
ABSTRACT | This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogs for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analog or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject. |
FILED | Thursday, September 22, 2016 |
APPL NO | 15/273147 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class A61K 31/137 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130600 | Rabinowitz et al. |
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APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York); The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Joshua Rabinowitz (Princeton, New Jersey); Jurre Kamphorst (Glasgow, United Kingdom); Craig Thompson (New York, New York); Justin Cross (New York, New York) |
ABSTRACT | Methods and compositions for treating Ras-related cancers are provided that involve targeting lipid scavenging. Methods and compositions for identifying and/or characterizing more or less responsive cancers are also provided. |
FILED | Friday, May 09, 2014 |
APPL NO | 14/890106 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) A23L 33/12 (20160801) A23L 33/17 (20160801) A23L 33/115 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/308 (20130101) A23V 2250/18 (20130101) A23V 2250/186 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) Original (OR) Class A61K 31/66 (20130101) A61K 31/202 (20130101) A61K 31/202 (20130101) A61K 31/685 (20130101) A61K 36/889 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) G01N 2500/10 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130626 | Govindan et al. |
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APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
INVENTOR(S) | Serengulam V. Govindan (Summit, New Jersey); David M. Goldenberg (Mendham, New Jersey) |
ABSTRACT | The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to EGP-1 (TROP-2), CEACAM5, CEACAM6, CD74, CD19, CD20, CD22, CSAp, HLA-DR, AFP or MUC5ac and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 24 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. |
FILED | Friday, September 30, 2016 |
APPL NO | 15/281453 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/481 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/454 (20130101) A61K 31/513 (20130101) A61K 31/675 (20130101) A61K 31/713 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) A61K 47/6851 (20170801) A61K 47/6853 (20170801) A61K 2039/55 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 16/303 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2887 (20130101) C07K 16/3007 (20130101) C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3061 (20130101) C07K 16/3092 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130628 | David et al. |
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APPLICANT(S) | Unity Biotechnology, Inc. (Brisbane, California); Buck Institute for Research on Aging (Novato, California); The Johns Hopkins University (Baltimore, Maryland); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
ASSIGNEE(S) | UNITY BIOTECHNOLOGY, INC. (Brisbane, California); BUCK INSTITUTE FOR RESEARCH ON AGING (Novato, California); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
INVENTOR(S) | Nathaniel David (San Francisco, California); Albert Davalos (San Rafael, California); Remi-Martin Laberge (San Francisco, California); Judith Campisi (Berkeley, California); Marco Demaria (Groningen, Netherlands); Alain Vasserot (Carlsbad, California); Chaekyu Kim (Pikesville, Maryland); Okhee Jeon (Baltimore, Maryland); Jennifer Elisseeff (Baltimore, Maryland); James L. Kirkland (Rochester, Minnesota); Tamar Tchkonia (Rochester, Minnesota); Yi Zhu (Rochester, Minnesota) |
ABSTRACT | This disclosure provides a technology for managing the sensation of pain in a subject in need thereof. Treatment methods according to this invention include administering to the subject a formulation that contains an effective amount of (4-[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone). |
FILED | Thursday, April 06, 2017 |
APPL NO | 15/481129 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0073 (20130101) A61K 31/404 (20130101) A61K 31/428 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/728 (20130101) A61K 31/4178 (20130101) A61K 31/4375 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 47/36 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101) C12N 2501/999 (20130101) C12N 2503/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130645 | Zebala et al. |
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APPLICANT(S) | Syntrix Biosystems Inc. (Auburn, Washington) |
ASSIGNEE(S) | Syntrix Biosystems, Inc. (Auburn, Washington) |
INVENTOR(S) | John A. Zebala (Issaquah, Washington); Dean Y. Maeda (Seattle, Washington); Aaron D. Schuler (Auburn, Washington) |
ABSTRACT | There is disclosed is a method of treating disease using compound having formula SX-682 alone or in combination with an antineoplastic agent, microtubule affecting agents, antineoplastic agents, anti-angiogenesis agents, VEGF receptor kinase inhibitors, antibodies against the VEGF receptor, interferon, or radiation. |
FILED | Tuesday, June 20, 2017 |
APPL NO | 15/627766 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/69 (20130101) Original (OR) Class A61K 31/69 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Technologies for Adaptation to Climate Change Y02A 50/402 (20180101) Y02A 50/411 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130650 | Huang et al. |
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APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania); Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania); The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Yanping Huang (Drexel Hill, Pennsylvania); Janis K. Burkhardt (Ardmore, Pennsylvania); Taku Kambayashi (Malvern, Pennsylvania) |
ABSTRACT | Compositions and methods are provided for the treatment and/or prevention of an inflammatory and/or autoimmune disease or disorder. |
FILED | Tuesday, January 27, 2015 |
APPL NO | 15/114572 |
ART UNIT | 1674 — Organic Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2217/206 (20130101) A01K 2227/105 (20130101) A01K 2267/0387 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 35/17 (20130101) A61K 35/28 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130661 | Veves et al. |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Trustees of Tufts College (Medford, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | Aristidis Veves (Quincy, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Jonathan Garlick (Brookline, Massachusetts) |
ABSTRACT | The present invention provides devices and methods for improving wound healing, in particular, in diabetic subjects. |
FILED | Monday, May 11, 2015 |
APPL NO | 14/709258 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/33 (20130101) Original (OR) Class A61K 38/18 (20130101) A61K 38/18 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/3804 (20130101) A61L 2300/414 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130663 | Bishai et al. |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | The John Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | William R. Bishai (Baltimore, Maryland); Ruchi Jain Dey (Baltimore, Maryland); Bappaditya Dey (Baltimore, Maryland); Laurene Cheung (Baltimore, Maryland) |
ABSTRACT | The present invention includes the discovery of a strain of Mycobacterium comprising an expression vector encoding a di-adenylate cyclase enzyme. The Mycobacterium is selected from the group consisting of Mycobacterium tuberculosis, Mycobacterium bovis, or a combination thereof and the preferred strain of Mycobacterium is BCG. The preferred expression vector is a mycobacterial expression vector including an hsp60 promoter and a DNA sequence of diadenylate cyclase (disA), or a functional part thereof. The strains of Mycobacterium are used in therapeutic applications including tuberculosis and cancer. |
FILED | Wednesday, February 10, 2016 |
APPL NO | 15/550434 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 39/04 (20130101) A61K 48/00 (20130101) A61K 2039/522 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130680 | Shah |
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APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Khalid Shah (Andover, Massachusetts) |
ABSTRACT | The technology described herein is directed to methods and compositions directed to the treatment of cancer, e.g. using multifunctional receptor targeted cancer therapeutics. |
FILED | Tuesday, February 07, 2017 |
APPL NO | 15/426079 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 39/39558 (20130101) A61K 47/6851 (20170801) A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/71 (20130101) C07K 14/525 (20130101) C07K 14/4747 (20130101) C07K 16/30 (20130101) C07K 16/2833 (20130101) C07K 16/2863 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) C07K 2319/035 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130683 | Borlongan et al. |
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FUNDED BY |
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APPLICANT(S) | Cesario Venturina Borlongan (Tampa, Florida); Paul R. Sanberg (Spring Hill, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Cesario Venturina Borlongan (Tampa, Florida); Paul R. Sanberg (Spring Hill, Florida) |
ABSTRACT | A combined therapy of human umbilical cord blood cells (hUCB) and G-CSF at the acute stage of TBI was tested as a therapeutic for progressive secondary effects of chronic TBI. Rats were treated with saline carrier, or therapeutic in carrier as follows; G-CSF, hUCB, or hUCB and G-CSF, 7-days after TBI. Eight weeks later, behavioral testing was performed and brains harvested to analyze hippocampal cell loss, neuroinflammatory response, and neurogenesis. Results revealed that the monotherapies partially suppressed neuroinflammation and reduced hippocampal cell loss. However, combined therapy of hUCB and G-CSF robustly dampened neuroinflammation, while enhancing endogenous neurogenesis and reducing hippocampal cell loss. Vigorous and long-lasting recovery of motor function accompanied the combined therapy, which was either moderately or short-lived in the monotherapy conditions. These results suggest that combined treatment rather than monotherapy appears optimal for abrogating histophalogical and motor impairments in chronic TBI. |
FILED | Tuesday, August 11, 2015 |
APPL NO | 14/823637 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/51 (20130101) A61K 38/193 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130687 | Chen et al. |
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APPLICANT(S) | Qian Chen (Barrington, Rhode Island); Chathuraka T. Jayasuriya (North Providence, Rhode Island) |
ASSIGNEE(S) | Rhode Island Hospital (Providence, Rhode Island) |
INVENTOR(S) | Qian Chen (Barrington, Rhode Island); Chathuraka T. Jayasuriya (North Providence, Rhode Island) |
ABSTRACT | Methods for reducing the severity of an arthritic condition or repairing an osteochondral defect are carried out by administering to a subject compositions comprising a member of the matrilin family of proteins, e.g., a matrilin protein, fragment thereof, or nucleic acid encoding the protein or fragment. |
FILED | Thursday, January 05, 2012 |
APPL NO | 13/976617 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 48/005 (20130101) Peptides C07K 14/78 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130697 | Watanabe et al. |
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FUNDED BY |
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APPLICANT(S) | Shinji Watanabe (Madison, Wisconsin); Tokiko Watanabe (Madison, Wisconsin); Yoshihiro Kawaoka (Middleton, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
INVENTOR(S) | Shinji Watanabe (Madison, Wisconsin); Tokiko Watanabe (Madison, Wisconsin); Yoshihiro Kawaoka (Middleton, Wisconsin) |
ABSTRACT | The invention provides a vaccine comprising an effective amount of an isolated recombinant influenza virus comprising a mutant M gene segment that is mutated so that upon viral replication the mutant M gene expresses a functional M1 protein and a mutant M2 protein with a deletion of the cytoplasmic tail and either lacking a transmembrane domain or having a mutated transmembrane domain. |
FILED | Wednesday, March 23, 2011 |
APPL NO | 13/070110 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/543 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130700 | Taubenberger |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, DHHS (Washington, District of Columbia) |
INVENTOR(S) | Jeffery K. Taubenberger (Springfield, Virginia) |
ABSTRACT | This disclosure provides compositions that include a mixture of viral like particles (VLPs), expressing different individual influenza hemagglutinin (HA) proteins that elicit broadly reactive immune responses to a wide variety of influenza viruses. For example, the composition can include at least two different influenza VLPs, a first VLP comprising a first HA polypeptide and a second VLP comprising a second influenza HA polypeptide, wherein the first and the second HA polypeptide are different subtypes and/or are from different influenza viruses, and a pharmaceutically acceptable carrier and/or an adjuvant. Methods of using the disclosed polymeric influenza VLP compositions to stimulate an immune response against influenza viruses, for example as a pre-pandemic or a seasonal vaccine, are provided. |
FILED | Friday, May 08, 2015 |
APPL NO | 15/317593 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/543 (20130101) A61K 2039/5258 (20130101) A61K 2039/55572 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/16223 (20130101) C12N 2760/16234 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130703 | Kousoulas |
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FUNDED BY |
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APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
INVENTOR(S) | Konstantin G. Kousoulas (Baton Rouge, Louisiana) |
ABSTRACT | The present invention provides vaccines for treating or preventing a herpes simplex virus infection and methods of using and making the vaccine. Further provided are recombinant herpes simplex virus genomes, recombinant viruses, and immunogenic compositions. |
FILED | Friday, May 08, 2015 |
APPL NO | 15/310004 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) Original (OR) Class A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16634 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130717 | Ndinguri et al. |
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APPLICANT(S) | Eastern Kentucky University (Richmond, Kentucky) |
ASSIGNEE(S) | Eastern Kentucky University (Richmond, Kentucky) |
INVENTOR(S) | Margaret Ndinguri (Richmond, Kentucky); Lindsay Calderon (Lexington, Kentucky) |
ABSTRACT | The conjugation of luteinizing hormone-releasing hormone (LHRH) with activated cisplatin using a malonate linker gives rise to a new Platinum-LHRH conjugate that effectively targets tumor cells that express the LHRH receptor. The Pt-LHRH conjugate may be used in a method for killing or inhibiting the growth of a tumor cell, especially in late state, highly invasive and aggressive stage IV tumors and in reoccurring tumors. |
FILED | Friday, December 02, 2016 |
APPL NO | 15/367428 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/24 (20130101) A61K 47/64 (20170801) A61K 47/48246 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) Peptides C07K 7/23 (20130101) C07K 19/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130718 | Goldenberg et al. |
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FUNDED BY |
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APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
ASSIGNEE(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
INVENTOR(S) | David M. Goldenberg (Mendham, New Jersey); Serengulam V. Govindan (Summit, New Jersey) |
ABSTRACT | The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to Trop-2 or CEACAM5 and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 16 mg/kg, preferably 4, 6, 8, 9, 10, 12, or 16 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. Surprisingly, the immunoconjugate is effective to treat cancers that are refractory to or relapsed from irinotecan. |
FILED | Tuesday, October 04, 2016 |
APPL NO | 15/285134 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/454 (20130101) A61K 31/513 (20130101) A61K 31/675 (20130101) A61K 31/713 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7088 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 41/0038 (20130101) A61K 45/06 (20130101) A61K 47/486 (20130101) A61K 47/48384 (20130101) A61K 47/48569 (20130101) Original (OR) Class A61K 47/48584 (20130101) A61K 47/48615 (20130101) A61K 47/48715 (20130101) A61K 51/1045 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1001 (20130101) A61N 2005/1021 (20130101) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2887 (20130101) C07K 16/3007 (20130101) C07K 16/3076 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/732 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130748 | Nyberg et al. |
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APPLICANT(S) | Scott L. Nyberg (Rochester, Minnesota); Stephen M. Corner (Rochester, Minnesota); Bruce Amiot (Coon Rapids, Minnesota) |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Scott L. Nyberg (Rochester, Minnesota); Stephen M. Corner (Rochester, Minnesota); Bruce Amiot (Coon Rapids, Minnesota) |
ABSTRACT | This document provides bioartificial liver (BAL) devices. Methods for making and using BAL devices also are provided. |
FILED | Friday, March 12, 2010 |
APPL NO | 13/256337 |
ART UNIT | 1799 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3472 (20130101) Original (OR) Class A61M 1/3479 (20140204) A61M 1/3486 (20140204) A61M 1/3489 (20140204) A61M 2205/103 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/02 (20130101) C12M 25/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131133 | Bentz et al. |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
INVENTOR(S) | Brian Zahler Bentz (Albuquerque, New Mexico); Kevin J Webb (West Lafayette, Indiana) |
ABSTRACT | An optically heterogeneous phantom structure for use in optical imaging techniques. The phantom structure includes an external shape simulating an object to be subjected to an optical imaging technique, the external shape defining an external surface that encloses an internal volume of the external shape; and an optically heterogeneous material filling the internal volume and having heterogeneous optical properties for simulating at least one optical parameter of at least one region within the object. A method of producing the optically heterogeneous phantom structure. The method includes selectively depositing precursors of a first material and a second material by 3D printing so that the precursor of the second material is surrounded by the precursor of the first material within a predetermined internal region of the precursor of the first material, and forming the phantom structure. Variations of the method include additives to the materials. |
FILED | Thursday, October 12, 2017 |
APPL NO | 15/782179 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/583 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/40 (20170801) B29C 64/129 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0026 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/40 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Original (OR) Class Image Data Processing or Generation, in General G06T 11/003 (20130101) Pictorial Communication, e.g Television H04N 5/372 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131637 | Abdel-Meguid et al. |
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APPLICANT(S) | Shifa Biomedical Corporation (Malvern, Pennsylvania); Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Shifa Biomedical Corporation (Malvern, Pennsylvania); Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
INVENTOR(S) | Sherin Salaheldin Abdel-Meguid (Exton, Pennsylvania); Magid Abou-Gharbia (Exton, Pennsylvania); Benjamin Blass (Eagleville, Pennsylvania); Wayne Childers (New Hope, Pennsylvania); Nabil Elshourbagy (West Chester, Pennsylvania); Victor Ghidu (Philadelphia, Pennsylvania); Rogelio Martinez (Trenton, New Jersey); Harold Meyers (Weston, Massachusetts); Shaker A. Mousa (Wynantskill, New York) |
ABSTRACT | Disclosed are compounds of the class of 2-phenylacetamides that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia. |
FILED | Tuesday, March 11, 2014 |
APPL NO | 14/767126 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/18 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/42 (20130101) A61K 31/167 (20130101) A61K 31/235 (20130101) A61K 31/245 (20130101) A61K 31/397 (20130101) A61K 31/401 (20130101) A61K 31/415 (20130101) A61K 31/435 (20130101) A61K 31/437 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4164 (20130101) A61K 31/4418 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 235/38 (20130101) C07C 237/42 (20130101) C07C 271/28 (20130101) C07C 275/40 (20130101) C07C 275/42 (20130101) C07C 311/47 (20130101) C07C 2601/02 (20170501) C07C 2601/08 (20170501) Heterocyclic Compounds C07D 211/14 (20130101) C07D 211/70 (20130101) C07D 211/96 (20130101) C07D 213/68 (20130101) C07D 213/74 (20130101) C07D 213/82 (20130101) C07D 231/12 (20130101) C07D 233/90 (20130101) C07D 239/42 (20130101) Original (OR) Class C07D 241/04 (20130101) C07D 241/08 (20130101) C07D 261/08 (20130101) C07D 295/14 (20130101) C07D 401/06 (20130101) C07D 403/12 (20130101) C07D 471/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131658 | DeGrado et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | William F. DeGrado (San Francisco, California); Dean Sheppard (Oakland, California); Hyunil Jo (Lafayette, California); Nilgun Isik Reed (San Francisco, California); Youzhi Tang (San Francisco, California) |
ABSTRACT | Provided herein, inter alia, are methods and compositions for inhibiting αvβ1 integrin and for treating fibrosis. |
FILED | Tuesday, March 29, 2016 |
APPL NO | 15/083836 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Tables; Desks; Office Furniture; Cabinets; Drawers; General Details of Furniture A47B 46/00 (20130101) A47B 47/0083 (20130101) A47B 96/1416 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/002 (20130101) A61M 31/007 (20130101) Heterocyclic Compounds C07D 207/48 (20130101) C07D 211/96 (20130101) C07D 277/06 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 409/12 (20130101) C07D 413/12 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/1488 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131659 | Doroshow et al. |
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APPLICANT(S) | THE UNITED STATES OF AMERICA as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia); STARKS ASSOCIATES INC. (Buffalo, New York) |
ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia); STARKS ASSOCIATES INC. (Buffalo, New York) |
INVENTOR(S) | James Halpern Doroshow (Bethesda, Maryland); Prabhakar Risbood (Germantown, Maryland); Jiamo Lu (Potomac, Maryland); Krishnendu Roy (Gaithersburg, Maryland); Charles T. Kane, Jr. (East Amherst, New York); Md Tafazzal Hossain (Amherst, New York) |
ABSTRACT | Disclosed herein are novel iodonium analogs having anticancer and anti-inflammatory activity. |
FILED | Monday, April 06, 2015 |
APPL NO | 15/302566 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/381 (20130101) A61K 31/4745 (20130101) Acyclic or Carbocyclic Compounds C07C 43/225 (20130101) C07C 205/12 (20130101) C07C 233/15 (20130101) Heterocyclic Compounds C07D 333/28 (20130101) C07D 347/00 (20130101) C07D 409/12 (20130101) C07D 409/14 (20130101) C07D 471/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131668 | Backes et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Washington Through Its Center For Commercialization (Seattle, Washington) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Washington Through Its Center For Commercialization (Seattle, Washington) |
INVENTOR(S) | Bradley J. Backes (San Francisco, California); Dustin J. Maly (Seattle, Washington); Scott A. Oakes (San Francisco, California); Feroz R. Papa (San Francisco, California); Gayani Perera (Negegoda, Sri Lanka); Likun Wang (San Francisco, California) |
ABSTRACT | Described herein, inter alia, are compositions and methods of using the same for modulating the activity of Ire1 using for example, substituted imidazopyrazine compounds. |
FILED | Thursday, March 26, 2015 |
APPL NO | 14/670088 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131687 | Dai |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Mingji Dai (West Lafayette, Indiana) |
ABSTRACT | A method of forming a probe, wherein the method includes converting cholenic acid into a compound with a terminal alkyne group, wherein the converting the cholenic acid comprises using a sequence, wherein the sequence comprises synthesizing a THP-protection group, LiAlH4 reduction, Dess-Martin oxidation, and Seyferth-Gilbert-Bestmann homologation. The method additionally includes forming A-Chol by removing the THP-protection. Further, the method includes forming PhA-Chol from the compound with the terminal alkyne group via a palladiumcatalyzed Sonogashira reaction. Additionally, the method includes forming PhDY-Chol from the compound with the terminal alkyne group via a coppercatalyzed Cadiot-Chodkiewicz reaction. |
FILED | Tuesday, June 27, 2017 |
APPL NO | 15/634567 |
ART UNIT | 1671 — Organic Chemistry |
CURRENT CPC | Steroids C07J 9/00 (20130101) Original (OR) Class C07J 9/005 (20130101) C07J 17/00 (20130101) C07J 41/0094 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131691 | Mochly-Rosen et al. |
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APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Daria Mochly-Rosen (Menlo Park, California); Nir Qvit (Menlo Park, California); Marie-Helene Disatnik Dziesietnik (Palo Alto, California) |
ABSTRACT | A peptide composition is provided which specifically inhibits the ability of δ-protein kinase C (δPKC) to phosphorylate pyruvate dehydrogenase kinase (PDK) under ischemic conditions. The peptide composition is useful for treating or reducing tissue damage resulting from ischemia and/or reperfusion. |
FILED | Tuesday, November 17, 2015 |
APPL NO | 14/943735 |
ART UNIT | 1676 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Enzymes C12Y 207/11002 (20130101) C12Y 207/11013 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131695 | Garcia-Sastre et al. |
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APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
INVENTOR(S) | Adolfo Garcia-Sastre (New York, New York); Peter Palese (New York, New York); Florian Krammer (New York, New York); Natalie Pica (New York, New York); Dirk Eggink (New York, New York); Rafael A. Medina-Silva (Santiago, Chile); Rong Hai (New York, New York) |
ABSTRACT | Provided herein are flu hemagglutinin polypeptides, including chimeric influenza virus hemagglutinin polypeptides, and flu hemagglutinin polypeptides comprising modified glycosylation sites and non-naturally glycosylation sites, compositions comprising the same, vaccines comprising the same and methods of their use. |
FILED | Wednesday, September 19, 2012 |
APPL NO | 14/345816 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 2039/53 (20130101) A61K 2039/521 (20130101) A61K 2039/5258 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/14143 (20130101) C12N 2760/16122 (20130101) C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/16162 (20130101) C12N 2760/16171 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131699 | Storkus et al. |
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APPLICANT(S) | University Of Pittsburgh Of The Commonwealth System Of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University Of Pittsburgh Of the Commonwealth System Of Higher (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Walter J. Storkus (Glenshaw, Pennsylvania); Michael S. Kinch (Laytonsville, Maryland) |
ABSTRACT | EphA2 T-cell epitope are provided herein. The epitopes include peptides corresponding to specific fragments of human EphA2 protein containing one or more T-cell epitopes, and conservative derivatives thereof. The EphA2 T-cell epitopes are useful in an assay, such as an ELISPOT assay, that may be used to determine and/or quantify a patient's immune responsiveness to EphA2. The epitopes also are useful in methods of modulating a patient's immune reactivity to EphA2, which has substantial utility as a treatment for cancers that overexpress EphA2, such as renal cell carcinoma (RCC). The EphA2 epitopes also can be used to vaccinate a patient against EphA2, by in vivo or ex vivo methods. |
FILED | Friday, June 03, 2016 |
APPL NO | 15/173209 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1793 (20130101) A61K 39/0011 (20130101) A61K 2039/55566 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/47 (20130101) C07K 14/705 (20130101) C07K 14/4748 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) G01N 33/5091 (20130101) G01N 33/56966 (20130101) G01N 33/56972 (20130101) G01N 2333/57 (20130101) G01N 2333/5409 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131704 | Marasco et al. |
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FUNDED BY |
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APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts); Xiangchun Tang (West Roxbury, Massachusetts) |
ABSTRACT | The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof. |
FILED | Monday, April 27, 2015 |
APPL NO | 15/306617 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/507 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/13 (20130101) C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2319/40 (20130101) C07K 2319/43 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16043 (20130101) C12N 2770/20022 (20130101) C12N 2810/609 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2469/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131705 | McBride et al. |
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FUNDED BY |
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APPLICANT(S) | Research Development Foundation (Carson City, Nevada) |
ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
INVENTOR(S) | Jere W. McBride (League City, Texas); Tian Luo (Galveston, Texas) |
ABSTRACT | The present invention concerns VLPT immunoreactive compositions for E. chaffeensis and compositions related thereto, including vaccines, antibodies, polypeptides, peptides, and polynucleotides. In particular, epitopes for E. chaffeensis VLPT are disclosed. |
FILED | Thursday, November 16, 2017 |
APPL NO | 15/814942 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/0233 (20130101) Peptides C07K 14/29 (20130101) C07K 16/1246 (20130101) Original (OR) Class C07K 17/00 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/29 (20130101) G01N 2333/195 (20130101) G01N 2333/43556 (20130101) Technologies for Adaptation to Climate Change Y02A 50/403 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131706 | Bansal |
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FUNDED BY |
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APPLICANT(S) | NovelMed Therapeutics, Inc. (Cleveland, Ohio) |
ASSIGNEE(S) | NOVELMED THERAPEUTICS, INC. (Cleveland, Ohio) |
INVENTOR(S) | Rekha Bansal (Cleveland, Ohio) |
ABSTRACT | A pharmaceutical composition includes an isolated anti-Bb antibody or antigen binding portion thereof produced by a hybridoma cell line deposited under ATCC Accession Number PTA-8543 or an isolated anti-Bb antibody or antigen binding portion thereof that competitively inhibits binding of the antibody or antigen binding portion produced by the hybridoma cell line deposited under ATCC Accession Number PTA-8543 to the Bb segment of factor B; and a pharmaceutically acceptable carrier. |
FILED | Monday, March 16, 2015 |
APPL NO | 14/659098 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131707 | Alam et al. |
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FUNDED BY |
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APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
INVENTOR(S) | Hasan B. Alam (Ann Arbor, Michigan); Yongqing Li (Ann Arbor, Michigan) |
ABSTRACT | The technology described herein is directed to the treatment of sepsis and/or septic shock by, e.g. administering an agent that can reduce the level of circulating citrullated histones. |
FILED | Friday, January 30, 2015 |
APPL NO | 15/106550 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) A61K 39/3955 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/44 (20130101) C07K 2317/76 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131745 | Thayumanavan et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Sankaran Thayumanavan (Amherst, Massachusetts); Rajasekhar R. Ramireddy (Amherst, Massachusetts) |
ABSTRACT | The invention generally relates to novel polymers and polymeric nanogels having biodegradable polymeric backbones, and compositions and methods of preparation and use thereof, for example, as guest-host polymer nano-assemblies and nano-delivery vehicles, which offer utilities in diverse fields including drug delivery, diagnostics and specialty materials. |
FILED | Thursday, December 14, 2017 |
APPL NO | 15/841388 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5146 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) C08G 69/26 (20130101) C08G 69/48 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131875 | Tedder et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas F. Tedder (Durham, North Carolina); Takashi Matsushita (Ishikawa, Japan); Yohei Iwata (Magoya, Japan); Koichi Yanaba (Tokyo, Japan); Jean-David Bouaziz (Maison-Alfort, France) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Thomas F. Tedder (Durham, North Carolina); Takashi Matsushita (Ishikawa, Japan); Yohei Iwata (Magoya, Japan); Koichi Yanaba (Tokyo, Japan); Jean-David Bouaziz (Maison-Alfort, France) |
ABSTRACT | The present invention relates to a distinct B cell subset, B10 cells, that regulate T cell mediated inflammatory responses through the secretion of interleukin-10 (IL-10). The invention also relates to the use of B10 cells in the manipulation of immune and inflammatory responses, and in the treatment of disease. Therapeutic approaches involving adoptive transfer of B10 cells, or expansion of their endogenous levels for controlling autoimmune or inflammatory diseases and conditions are described. Ablation of B10 cells, or inhibition of their IL-10 production can be used to upregulate immunodeficient conditions, ameliorate infectious diseases and/or to treat tumors/cancer. Diagnostic applications are also encompassed. |
FILED | Thursday, August 04, 2011 |
APPL NO | 13/814165 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0635 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5052 (20130101) G01N 33/6893 (20130101) G01N 2800/7095 (20130101) Technologies for Adaptation to Climate Change Y02A 50/388 (20180101) Y02A 50/463 (20180101) Y02A 50/471 (20180101) Y02A 50/484 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131878 | Palecek et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Sean P. Palecek (Veron, Wisconsin); Xiaoping Bao (Madison, Wisconsin); Xiaojun Lian (Solna, Sweden) |
ABSTRACT | Methods for generating high-yield, high-purity epicardial cells are described. Wnt/β-catenin signaling is first activated in human cardiac progenitor cells, by, for example, inhibiting Gsk-3 to induce differentiation into epicardial cells. Methods for long-term in vitro maintenance of human cardiac progenitor cell-derived epicardial cells and method comprising chemically defined, xeno-free, and albumin-free culture conditions are also provided. |
FILED | Tuesday, April 05, 2016 |
APPL NO | 15/091239 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 2500/38 (20130101) C12N 2500/95 (20130101) C12N 2501/15 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2533/54 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131900 | Pakhomova et al. |
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FUNDED BY |
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APPLICANT(S) | Olga Pakhomova (Norfolk, Virginia); Andrei G. Pakhomov (Norfolk, Virginia) |
ASSIGNEE(S) | OLD DOMINION UNIVERSITY RESEARCH FOUNDATION (Norfolk, Virginia) |
INVENTOR(S) | Olga Pakhomova (Norfolk, Virginia); Andrei G. Pakhomov (Norfolk, Virginia) |
ABSTRACT | Methods of enhancing membrane permeabilization in a cell are provided. A method includes disposing the cell between a first electrode and a second electrode and applying a plurality of electrical pulses between the first electrode and the second electrode. In the method, the plurality of electrical pulses include at least two trains of pulses separated by an interval greater than about 10 s. Further, the amplitude of the electrical pulses is selected to be greater than about 0.2 kV/cm. |
FILED | Tuesday, December 13, 2011 |
APPL NO | 13/994508 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131901 | Abrams et al. |
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FUNDED BY |
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APPLICANT(S) | SAGE SCIENCE, INC. (Beverly, Massachusetts) |
ASSIGNEE(S) | SAGE SCIENCE, INC. (Beverly, Massachusetts) |
INVENTOR(S) | Ezra S. Abrams (Newton, Massachusetts); Danny Yun (S. Hamilton, Massachusetts); Todd J. Barbera (Marblehead, Massachusetts); Douglas Grosvenor Sabin (Marblehead, Massachusetts); T. Christian Boles (Bedford, Massachusetts) |
ABSTRACT | Methods, systems and apparatus for automated extraction, purification, and processing of nucleic acids from biological samples are presented. In some embodiments, hydrogel supports are used to immobilize particulate biological input samples and extract nucleic acids during operations. The use of hydrogel facilitates automated sample processing on robotic liquid handling systems. Devices, methods, and systems are also provided for electrophoretic sample preparation. |
FILED | Thursday, October 15, 2015 |
APPL NO | 15/519516 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) Original (OR) Class C12N 15/1017 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44747 (20130101) G01N 27/44773 (20130101) G01N 27/44782 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131905 | Pandolfi et al. |
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FUNDED BY |
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APPLICANT(S) | Pier Paolo Pandolfi (Boston, Massachusetts); Laura Poliseno (New York, New York); Yvonne Tay (Brookline, Massachusetts); Leonardo Salmena (Brookline, Massachusetts) |
ASSIGNEE(S) | BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts) |
INVENTOR(S) | Pier Paolo Pandolfi (Boston, Massachusetts); Laura Poliseno (New York, New York); Yvonne Tay (Brookline, Massachusetts); Leonardo Salmena (Brookline, Massachusetts) |
ABSTRACT | The invention relates to the treatment and prevention of cancer by administering agents that inhibit the activity of microRNAs that modulate tumor suppressor genes, which can include PTEN, p53, and INPP4B, among others. Inhibitors can include oligonucleotides that are at least partially complementary to these miRNAs. In some embodiments, these inhibitors are chemically modified oliognucleotides, including locked nucleic acids (LNAs). |
FILED | Thursday, April 12, 2012 |
APPL NO | 14/111489 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3231 (20130101) C12N 2320/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131938 | Barany et al. |
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FUNDED BY |
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APPLICANT(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
INVENTOR(S) | Francis Barany (New York, New York); Monib Zirvi (Monmouth Junction, New Jersey); Norman P. Gerry (Philadelphia, Pennsylvania); Reyna Favis (Iselin, New Jersey); Richard Kliman (Iselin, New Jersey) |
ABSTRACT | The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The present invention further relates to an oligonucleotide array comprising of a support with the plurality of oligonucleotide probes immobilized on the support, a method of using the support to detect single-base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences, and a kit for such detection, which includes the support on which the oligonucleotides have been immobilized. |
FILED | Friday, July 07, 2017 |
APPL NO | 15/644273 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6837 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6874 (20130101) C12Q 1/6886 (20130101) C12Q 2521/319 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2527/107 (20130101) C12Q 2527/107 (20130101) C12Q 2527/107 (20130101) C12Q 2565/501 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131948 | Hare et al. |
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FUNDED BY |
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APPLICANT(S) | University of Miami (Miami, Florida) |
ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
INVENTOR(S) | Joshua M. Hare (Miami Beach, Florida); Bettina Heidecker (Miami, Florida) |
ABSTRACT | A novel transcriptomic biomarker for prognosis in heart failure has a direct clinical application in prediction of prognosis in new onset heart failure, heart disease, heart disorders and associated heart conditions. This approach should improve individualization of cardiac care and help identify patients at highest risk for circulatory collapse within the first years of presentation with heart failure. |
FILED | Thursday, July 17, 2014 |
APPL NO | 14/334024 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/50 (20130101) G01N 2800/325 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131960 | Hughes et al. |
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FUNDED BY |
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APPLICANT(S) | MONTANA MOLECULAR LLC (Bozeman, Montana) |
ASSIGNEE(S) | Montana Molecular LLC (Bozeman, Montana) |
INVENTOR(S) | Thomas E. Hughes (Bozeman, Montana); Paul H. Tewson (Bozeman, Montana); Anne Marie Quinn (Bozeman, Montana) |
ABSTRACT | Described herein are novel fluorescent sensors for Diacyl Glycerol (DAG) and phosphatidylinositol 4,5-bisphosphate (PIP2) that are based on circularly permuted fluorescent proteins. These sensors use less visible spectrum than FRET-based sensors, produce robust changes in fluorescence, and can be combined with one another, or with other sensors, in a multiplex assay on standard fluorescent plate readers or live cell imaging systems. |
FILED | Monday, January 16, 2017 |
APPL NO | 15/407111 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/00 (20130101) C07K 14/43595 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) C12N 9/1205 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class Enzymes C12Y 207/11013 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/502 (20130101) G01N 33/582 (20130101) G01N 33/5041 (20130101) G01N 2333/912 (20130101) G01N 2333/916 (20130101) G01N 2333/43595 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132775 | Santiago et al. |
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FUNDED BY |
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APPLICANT(S) | Juan G. Santiago (Stanford, California); Alexandre Persat (Metuchen, New Jersey); Giancarlo Garcia (Stanford, California); Charbel Eid (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Juan G. Santiago (Stanford, California); Alexandre Persat (Metuchen, New Jersey); Giancarlo Garcia (Stanford, California); Charbel Eid (Stanford, California) |
ABSTRACT | Techniques for enhanced isotachophoresis assays using additives with spatial gradients include forming a concentration gradient of an additive along a channel from an input port to an output port. The channel is used for isotachophoresis with ions of a leading electrolyte having a first mobility greater than a mobility of an analyte, and ions of a trailing electrolyte having a second mobility less than the mobility of the analyte. The additive is different from both the leading electrolyte and the trailing electrolyte; and the additive has a third mobility that assures the analyte will encounter the additive. The method further comprises introducing a mixture of the trailing electrolyte and a sample including the analyte. The method further comprises applying an electric field to the channel; and, measuring the analyte. |
FILED | Monday, August 17, 2015 |
APPL NO | 14/828487 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) G01N 27/44721 (20130101) G01N 27/44756 (20130101) Original (OR) Class G01N 27/44795 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132798 | Craighead et al. |
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FUNDED BY |
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APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Harold G. Craighead (Ithaca, New York); David R. Latulippe (Ithaca, New York); John T. Lis (Ithaca, New York); Abdullah Ozer (Vestal, New York); Kylan Szeto (Ithaca, New York) |
ABSTRACT | The present invention relates to a microcolumn device for selecting nucleic acid aptamers for single and multiple target molecules, as well as a method for making the microcolumn device. The present invention also relates to a system for selecting nucleic acid aptamers for single and multiple target molecules. The present invention further relates to methods of using the microcolumn device for selecting nucleic acid aptamers for multiple target molecules. Kits that include one or more microcolumn device and/or system of the present invention are also disclosed. |
FILED | Monday, May 13, 2013 |
APPL NO | 14/400229 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2330/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48 (20130101) G01N 33/5302 (20130101) G01N 33/5308 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132809 | Resnick et al. |
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FUNDED BY |
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APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
ASSIGNEE(S) | Rhote Island Hospital (Providence, Rhode Island) |
INVENTOR(S) | Murray B. Resnick (Sharon, Massachusetts); Andres Matoso (Providence, Rhode Island); Vincent A. Mukkada (Needham, Massachusetts); Shaolei Lu (Barrington, Rhode Island) |
ABSTRACT | A method is described for diagnosing eosinophilic esophagitis by studying the levels of expression of novel markers, including ALOX15 or metabolites thereof, TNFAIP6, FLG, SLURP1, or CRISP3. Also described are methods for treating eosinophilic esophagitis. |
FILED | Thursday, October 10, 2013 |
APPL NO | 14/435059 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/56 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 33/6869 (20130101) G01N 33/6893 (20130101) G01N 2333/90241 (20130101) G01N 2405/00 (20130101) G01N 2800/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132811 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Lei Zhang (Los Angeles, California); David T. Wong (Beverly Hills, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Lei Zhang (Los Angeles, California); David T. Wong (Beverly Hills, California) |
ABSTRACT | The present invention relates to the identification of pancreatic cancer biomarkers for the detection of early pancreatic cancer. The present invention also provides methods of diagnosing pancreatic cancer and distinguishing between pancreatic cancer and chronic pancreatitis. The present invention additionally provides kits that find use in the practice of the methods of the invention. |
FILED | Friday, June 25, 2010 |
APPL NO | 13/379341 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57438 (20130101) G01N 33/57488 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132818 | Sigurdsson |
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FUNDED BY |
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APPLICANT(S) | New York University (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Einar M. Sigurdsson (Scarsdale, New York) |
ABSTRACT | The present invention relates to antibody-based probes (including single domain antibody fragment, scFv molecules, antibodies, antibody fragments, diabodies, and the epitope-binding domains thereof) that are capable of immunospecifically and selectively binding to a phospho-serine-containing epitope of Tau, such as, for example, Tau-phospho-serine 396/404 peptide. Such imaging ligands are useful to detect pathological Tau protein conformer if present in a biological sample, especially in conjunction with the diagnosis of Alzheimer's disease or other tauopathy, and thus provide a diagnostic for Alzheimer's disease and other Tau pathologies. The scFv molecules of the present invention have utility as diagnostic markers for, Alzheimer's disease and related tauopathies and as pharmaceutical compositions for the treatment of such conditions. |
FILED | Monday, July 06, 2015 |
APPL NO | 15/324141 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0058 (20130101) Peptides C07K 16/18 (20130101) C07K 2317/34 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2440/14 (20130101) G01N 2800/2821 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132890 | Horng |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Debra E. Horng (Madison, Wisconsin) |
ABSTRACT | A system and method are provided for determining a spatial distribution of susceptibility in a subject using a magnetic resonance imaging (MRI) system. The method includes directing the MRI system to acquire imaging data from an imaging volume within a subject, wherein the imaging volume is subject to both background fields (BB) originating outside the imaging volume and local fields (BL) originating from tissue within the imaging volume. The method also includes selecting a size and non-central compute point for an extended Poisson kernel to be applied to the imaging data, subtracting from a delta function to control the background fields (BB) but not the local fields (BL), and producing a susceptibility report attributable to the local fields (BL). |
FILED | Friday, March 18, 2016 |
APPL NO | 15/074515 |
ART UNIT | 2868 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/443 (20130101) Original (OR) Class G01R 33/56545 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132898 | Kecskemeti et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Steven Ryan Kecskemeti (Madison, Wisconsin); Andrew L. Alexander (Madison, Wisconsin) |
ABSTRACT | Described here are a system and method for obtaining multiple different images when performing a single scan of a subject with a magnetic resonance imaging (“MRI”) system. The scan includes the application of two or more magnetization preparation radio frequency (“RF”) pulses, such as inversion recovery (“IR”) pulses. Data is acquired after the application of each magnetization preparation RF pulse, thus allowing the acquisition of multiple different images of the subject in a single scan. Using this approach, the same information that used to require multiple different scans of the subject can be acquired in one single scan, and in less time than would be required to perform the multiple scans. |
FILED | Friday, May 24, 2013 |
APPL NO | 13/902378 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4818 (20130101) G01R 33/5602 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132902 | Cheng et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Joseph Y. Cheng (Stanford, California); John M. Pauly (Stanford, California); Marcus T. Alley (Palo Alto, California); Shreyas S. Vasanawala (Stanford, California); Michael Lustig (Berkeley, California) |
ABSTRACT | A method for an object in a magnetic resonance image (MRI) system for providing at least one velocity indicative magnetic resonance image (MRI) with motion correction of the object is provided. Velocity encoding gradients in at least one spatial direction are provided from the MRI system. Spatial frequency data resulting from the encoding gradients are acquired through the MRI system. Image signals are provided by the MRI system. Image data resulting from the image signals are acquired through the MRI system. At least one motion corrected and velocity indicative magnetic resonance image is created from the acquired spatial frequency data and image data. |
FILED | Tuesday, May 26, 2015 |
APPL NO | 14/721876 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4822 (20130101) G01R 33/5676 (20130101) G01R 33/56316 (20130101) G01R 33/56509 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132905 | Dzyubak et al. |
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FUNDED BY |
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APPLICANT(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Bogdan Dzyubak (Rochester, Minnesota); Jun Chen (Rochester, Minnesota); Richard Ehman (Rochester, Minnesota) |
ABSTRACT | A phantom for magnetic resonance elastography (MRE) is provided. In particular, systems and methods for a phantom that is capable of generating a wave-like pattern in MRE images where a wavelength of the generated wave-like pattern is controlled by the phantom geometry. The geometrically controlled wavelength enables the phantom to calibrate MRE image acquisition and mechanical property calculation. |
FILED | Thursday, January 05, 2017 |
APPL NO | 15/399479 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134125 | Mauldin, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | Rivanna Medical LLC (Charlottesville, Virginia) |
ASSIGNEE(S) | Rivanna Medical LLC (Charlottesville, Virginia) |
INVENTOR(S) | Frank William Mauldin, Jr. (Charlottesville, Virginia); Kevin Owen (Crozet, Virginia) |
ABSTRACT | Techniques for processing ultrasound data. The techniques include using at least one computer hardware processor to perform obtaining ultrasound data generated based, at least in part, on one or more ultrasound signals from an imaged region of a subject; calculating shadow intensity data corresponding to the ultrasound data; generating, based at least in part on the shadow intensity data and at least one bone separation parameter, an indication of bone presence in the imaged region, generating, based at least in part on the shadow intensity data and at least one tissue separation parameter different from the at least one bone separation parameter, an indication of tissue presence in the imaged region; and generating an ultrasound image of the subject at least in part by combining the indication of bone presence and the indication of tissue presence. |
FILED | Wednesday, February 26, 2014 |
APPL NO | 14/770893 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/461 (20130101) A61B 8/0858 (20130101) A61B 8/0875 (20130101) A61B 8/5223 (20130101) A61B 8/5246 (20130101) A61B 8/5269 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) G06K 9/4661 (20130101) G06K 2009/4666 (20130101) Image Data Processing or Generation, in General G06T 5/009 (20130101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/30 (20170101) G06T 11/60 (20130101) G06T 15/08 (20130101) G06T 2200/04 (20130101) G06T 2207/10132 (20130101) G06T 2207/30008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134144 | Mistretta et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Charles A. Mistretta (Madison, Wisconsin); Charles M. Strother (Madison, Wisconsin); Gabriel Shaughnessy (Nashotah, Wisconsin) |
ABSTRACT | A system and method are provided for generating time resolved series of angiographic volume data having flow information. The system and method are configured to receive angiographic volume data acquired from a subject having received a dose of a contrast agent using an imaging system and process the angiographic volume data to generate angiographic volume images. The angiographic volume data is processed to derive flow information by determining a distance between two points along a vessel in the angiographic volume images and determining a phase at each of the two points along the vessel in the angiographic volume images. A flow direction or a velocity of flow within the vessel is determined using the distance between the two points along the vessel and the phase at each of the two points along the vessel. |
FILED | Tuesday, September 15, 2015 |
APPL NO | 14/855209 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02 (20130101) Image Data Processing or Generation, in General G06T 7/0081 (20130101) G06T 7/206 (20130101) G06T 7/2053 (20130101) Original (OR) Class G06T 2207/10076 (20130101) G06T 2207/10116 (20130101) G06T 2207/20224 (20130101) G06T 2207/30104 (20130101) G06T 2210/41 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134148 | Heine et al. |
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FUNDED BY |
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APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | John J. Heine (New Port Richey, Florida); Thomas A. Sellers (Tampa, Florida); Erin E. Fowler (Tampa, Florida) |
ABSTRACT | Breast density is a significant breast cancer risk factor measured from mammograms. Disclosed is a methodology for converting continuous measurements of breast density and calibrated mammograms into a four-state ordinal variable approximating the BI-RADS ratings. In particular, the present disclosure is directed to a calibration system for a specific full field digital mammography (FFDM) technology. The calibration adjusts for the x-ray acquisition technique differences across mammograms resulting in standardized images. The approach produced various calibrated and validated measures of breast density, one of which assesses variation in the mammogram referred to as Vc (i.e. variation measured from calibrated mammograms). The variation in raw mammograms [i.e. Vr] is a valid breast density risk factor in both FFDM in digitized film mammograms. |
FILED | Friday, May 30, 2014 |
APPL NO | 14/893632 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/502 (20130101) A61B 6/583 (20130101) A61B 6/5205 (20130101) A61B 6/5217 (20130101) Image Data Processing or Generation, in General G06T 5/40 (20130101) G06T 7/0014 (20130101) G06T 7/44 (20170101) G06T 7/403 (20130101) Original (OR) Class G06T 2207/10116 (20130101) G06T 2207/30068 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134181 | Black et al. |
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FUNDED BY |
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APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
INVENTOR(S) | Michael J. Black (Tuebingen, Germany); Peng Guan (Mountain View, California) |
ABSTRACT | A system generates a clothing deformation model which models one or more of a pose-dependent clothing shape variation which is induced by underlying body pose parameters, a pose-independent clothing shape variation which is induced by clothing size and underlying body shape parameters and a clothing shape variation including a combination of the pose-dependent clothing shape variation and/or the pose-independent clothing shape variation. The system generates, for an input human body, a custom-shaped garment associated with a clothing type by mapping, via the clothing deformation model, body shape parameters of the input human body to clothing shape parameters of the clothing type and dresses the input human body with the custom-shaped garment. |
FILED | Monday, June 12, 2017 |
APPL NO | 15/620614 |
ART UNIT | 2617 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) G06F 2217/32 (20130101) Image Data Processing or Generation, in General G06T 17/00 (20130101) Original (OR) Class G06T 19/20 (20130101) G06T 2210/16 (20130101) G06T 2219/2016 (20130101) G06T 2219/2021 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134572 | Laskin et al. |
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FUNDED BY |
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APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Julia Laskin (Richland, Washington); Son N. Nguyen (Richland, Washington); Andrey V. Liyu (Pasco, Washington) |
ABSTRACT | A system includes a mass spectrometer and associated sample interfacing equipment. The sample interfacing equipment includes a platform structured to support a sample thereon, a fluid source, a high voltage source, a dispensing probe electrically coupled to the high voltage source and defining a fluid dispensing passage therethrough, a collection probe defining a collection passage therethrough, a sensing arrangement coupled to the dispensing probe, and control logic responsive to the sensing arrangement to control distance between the dispensing probe and the sample. The dispensing probe facilitates formation of one or more ionized sample analytes when dispensing the fluid through the dispensing passage proximate to the sample on the platform. The collecting probe receives at least some of the one or more ionized sample analytes to pass through the collection passage into the mass spectrometer for analysis. |
FILED | Monday, August 01, 2016 |
APPL NO | 15/225585 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) H01J 49/0027 (20130101) Original (OR) Class H01J 49/0409 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135849 | Jha et al. |
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FUNDED BY |
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APPLICANT(S) | Niraj K. Jha (Westfield, New Jersey); Anand Raghunathan (West Lafayette, Indiana); Meng Zhang (Princeton, New Jersey) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | Niraj K. Jha (Westfield, New Jersey); Anand Raghunathan (West Lafayette, Indiana); Meng Zhang (Princeton, New Jersey) |
ABSTRACT | A medical device monitor (MedMon), method and computer readable medium is disclosed. The MedMon is configured to operate in a system having communications between a first medical device associated with a patient and a second device. The MedMon includes a receiver configured to snoop on communications between the first medical device and second device. An anomaly detector having a set of security polices is configured to detect an anomaly by analyzing the communications between the first medical device and second device for compliance with the security policies. A response generator configured to generate a response on a condition that an anomaly is detected. The response may be a warning message configured to warn the patient. The MedMon may include a transmitter configured to transmit the response. The response may be a jamming signal configured to disrupt communications between the first medical device and second device. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/839768 |
ART UNIT | 2491 — Cryptography and Security |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/14532 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 10130258 | Mao et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Ying Mao (Niskayuna, New York); Weston Blaine Griffin (Niskayuna, New York); Erin Jean Finehout (Clifton Park, New York); Ian Hart (Nassau, New York) |
ABSTRACT | An assistive sample collection and storage assembly for collecting, transferring and storing a biological sample includes a sample collection device having a first portion and a second portion. The first portion is configured to receive a sample collection member. The assembly includes a sample storage device comprising a sample substrate configured to receive at least a portion of the biological sample from the sample collection member. The assembly is configured to exist in a first state and a second state. The sample collection member is disposed at a determined distance from the sample substrate in the first state. At least a portion of the sample collection member is in physical contact with at least a portion of the sample substrate in the second state. The sample collection member is configured to apply a determined amount of contact force between the collection member and the sample substrate in the second state of the assembly. |
FILED | Tuesday, September 24, 2013 |
APPL NO | 14/035085 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0051 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130546 | Townsend et al. |
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FUNDED BY |
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APPLICANT(S) | Barrett Technology, LLC (Newton, Massachusetts) |
ASSIGNEE(S) | Barrett Technology, LLC (Newton, Massachusetts) |
INVENTOR(S) | William T. Townsend (Weston, Massachusetts); David Wilkinson (Dedham, Massachusetts); Alexander Jenko (Newton, Massachusetts); Julian Leland (Newton, Massachusetts); Arvind Ananthanarayanan (Newton, Massachusetts); James Patton (Winnetka, Illinois) |
ABSTRACT | A robotic device for operation in association with an appendage of a user, wherein the appendage of the user has an endpoint, the robotic device including: a base; and a robotic arm attached to the base and having an endpoint, the robotic arm having at least two active degrees of freedom relative to the base and being configured so that when the base is appropriately positioned relative to a user, the reference frame of the robotic device is oriented generally similarly to the reference frame of the user and motions of the endpoint of the appendage of the user are mimicked by motions of the endpoint of the robotic arm. |
FILED | Monday, September 29, 2014 |
APPL NO | 14/500810 |
ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0237 (20130101) A61H 1/0274 (20130101) Original (OR) Class A61H 2201/1638 (20130101) A61H 2201/1659 (20130101) A61H 2201/5007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130683 | Borlongan et al. |
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FUNDED BY |
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APPLICANT(S) | Cesario Venturina Borlongan (Tampa, Florida); Paul R. Sanberg (Spring Hill, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Cesario Venturina Borlongan (Tampa, Florida); Paul R. Sanberg (Spring Hill, Florida) |
ABSTRACT | A combined therapy of human umbilical cord blood cells (hUCB) and G-CSF at the acute stage of TBI was tested as a therapeutic for progressive secondary effects of chronic TBI. Rats were treated with saline carrier, or therapeutic in carrier as follows; G-CSF, hUCB, or hUCB and G-CSF, 7-days after TBI. Eight weeks later, behavioral testing was performed and brains harvested to analyze hippocampal cell loss, neuroinflammatory response, and neurogenesis. Results revealed that the monotherapies partially suppressed neuroinflammation and reduced hippocampal cell loss. However, combined therapy of hUCB and G-CSF robustly dampened neuroinflammation, while enhancing endogenous neurogenesis and reducing hippocampal cell loss. Vigorous and long-lasting recovery of motor function accompanied the combined therapy, which was either moderately or short-lived in the monotherapy conditions. These results suggest that combined treatment rather than monotherapy appears optimal for abrogating histophalogical and motor impairments in chronic TBI. |
FILED | Tuesday, August 11, 2015 |
APPL NO | 14/823637 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/51 (20130101) A61K 38/193 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130696 | Richardson et al. |
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FUNDED BY |
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APPLICANT(S) | Charles Richardson (Cambridge, Massachusetts); Thomas S. Vedvick (Cambridge, Massachusetts); Thomas R. Foubert (Cambridge, Massachusetts); William Tino (Cambridge, Massachusetts) |
ASSIGNEE(S) | TAKEDA VACCINES, INC. (Cambridge, Massachusetts) |
INVENTOR(S) | Charles Richardson (Cambridge, Massachusetts); Thomas S. Vedvick (Cambridge, Massachusetts); Thomas R. Foubert (Cambridge, Massachusetts); William Tino (Cambridge, Massachusetts) |
ABSTRACT | The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject. |
FILED | Thursday, September 18, 2008 |
APPL NO | 12/678813 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/543 (20130101) A61K 2039/5258 (20130101) A61K 2039/55572 (20130101) A61K 2039/55583 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/16023 (20130101) C12N 2770/16034 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130716 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Andrew Keefe (Seattle, Washington); Hong Xue (Pleasanton, California) |
ABSTRACT | Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates. |
FILED | Wednesday, October 29, 2014 |
APPL NO | 14/526846 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4826 (20130101) A61K 47/48176 (20130101) Original (OR) Class Enzymes C12Y 304/21001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130766 | Bibian et al. |
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FUNDED BY |
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APPLICANT(S) | Stéphane Bibian (Cleveland Heights, Ohio); Tatjana Zikov (Cleveland Heights, Ohio) |
ASSIGNEE(S) | NeuroWave Systems Inc. (Cleveland Heights, Ohio) |
INVENTOR(S) | Stéphane Bibian (Cleveland Heights, Ohio); Tatjana Zikov (Cleveland Heights, Ohio) |
ABSTRACT | A system and method provides closed-loop sedation, anesthesia, or analgesia by monitoring EEG and automatically adjusting the delivery of sedative, anesthetic, and/or analgesic drugs to maintain that desired or predetermined level of cortical at all echelons of care. The system and method further monitor the subject's cortical activity to detect occurrence of burst suppression which can be indicative of unsafe depth of anesthesia or sedation. Further, the system and methods provide for alteration or cessation of the administration of anesthesia or sedation based on the occurrence of burst suppression to mitigate harm to the subject. |
FILED | Monday, October 05, 2015 |
APPL NO | 14/874736 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0476 (20130101) A61B 5/04012 (20130101) A61B 5/4821 (20130101) A61B 5/4839 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 16/0003 (20140204) A61M 2202/048 (20130101) A61M 2205/18 (20130101) A61M 2230/005 (20130101) A61M 2230/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130834 | Peterson et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Edgewood Chemical and Biological Center (APG, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Gregory W. Peterson (Belcamp, Maryland); Joseph P. Myers (Havre de Grace, Maryland); George W. Wagner (Elkton, Maryland); Matthew J. Shue (New Freedom, Pennsylvania); John P. Davies, Jr. (North East, Maryland); Joseph A Rossin (Columbus, Ohio) |
ABSTRACT | The present invention is directed towards a composition for decontaminating surfaces contaminated with toxic chemicals/substances, comprising at least one type of metal oxyhydroxide such as zirconium hydroxide, Zr(OH)4, optionally with added water for hydration of the solid, mixed into a carrier liquid used for application to a contaminated surface. |
FILED | Friday, September 09, 2016 |
APPL NO | 15/261149 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/30 (20130101) Original (OR) Class A62D 2101/02 (20130101) A62D 2101/04 (20130101) A62D 2101/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130846 | Carter et al. |
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FUNDED BY |
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APPLICANT(S) | THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts) |
ASSIGNEE(S) | THE CHARLES STARK DRAPPER LABORATORY, INC. (Cambridge, Massachusetts) |
INVENTOR(S) | David J. Carter (Concord, Massachusetts); William W. McFarland (Waltham, Massachusetts); Glenn Ogrodnik (Cohasset, Massachusetts); Graham Arrick (Cambridge, Massachusetts); Maxim Bushmelov (Natick, Massachusetts) |
ABSTRACT | A hybrid adhesion system includes an adhesion head including at least one suction cup and a handle and a vacuum generator mechanically coupled to the adhesion head. The vacuum generator includes at least one pneumatic cylinder having an internal volume in fluid communication with the at least one suction cup and a piston having a piston rod mechanically coupled to a manual actuator. |
FILED | Wednesday, June 15, 2016 |
APPL NO | 15/183266 |
ART UNIT | 3748 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/0083 (20130101) A63B 23/03541 (20130101) A63B 27/00 (20130101) Original (OR) Class A63B 29/08 (20130101) A63B 69/0048 (20130101) A63B 2225/055 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 47/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131427 | Blyth et al. |
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FUNDED BY |
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APPLICANT(S) | Robert Matthew Blyth (Fort Worth, Texas); Paul Raymond Wilkinson (Media, Pennsylvania) |
ASSIGNEE(S) | Bell Helicopter Textron Inc. (Fort Worth, Texas); The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Robert Matthew Blyth (Fort Worth, Texas); Paul Raymond Wilkinson (Media, Pennsylvania) |
ABSTRACT | A system includes a first mast torque transfer system, a second mast torque transfer system coupled to the first mast torque transfer system, and a torque limiting system. The torque limiting system includes a first sensor configured to determine a torque of the first mast torque transfer system, a second sensor configured to determine a torque of the second mast torque transfer system, and a processor configured to determine a differential torque between the torque of the first mast torque transfer system and the torque of the second mast torque transfer system and configured to control at least one of a torque input and a torque output to at least one of the first and second mast torque transfer systems as a function of the determined differential torque. |
FILED | Wednesday, November 04, 2015 |
APPL NO | 14/932241 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Aeroplanes; Helicopters B64C 11/303 (20130101) B64C 11/308 (20130101) B64C 29/0033 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131568 | Nguyen et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Vinh Q. Nguyen (Fairfax, Virginia); Mikhail Kotov (Silver Spring, Maryland); Daniel J. Gibson (Cheverly, Maryland); Shyam S. Bayya (Ashburn, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Gryphon A. Drake (Potomac, Maryland) |
ABSTRACT | The present invention provides a method for synthesizing high optical quality multicomponent chalcogenide glasses without refractive index perturbations due to striae, phase separation or crystal formation using a two-zone furnace and multiple fining steps. The top and bottom zones are initially heated to the same temperature, and then a temperature gradient is created between the top zone and the bottom zone. The fining and cooling phase is divided into multiple steps with multiple temperature holds. |
FILED | Thursday, March 03, 2016 |
APPL NO | 15/059637 |
ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 5/06 (20130101) C03B 2201/86 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131587 | Diviacchi |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Edgewood Chemical and Biological Center (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Giancarlo Diviacchi (Baltimore, Maryland) |
ABSTRACT | A mixture and method of creating the mixture includes mixing hexachloroethane, stannous oxide, and aluminum together. The mixture may be loaded into at least one canister. The mixture may be combusted to create a smoke screen. The loading of the mixture into the at least one canister may include pressurized loading at loading pressures in the range of approximately 2300 psi to 3600 psi. The hexachloroethane may include approximately 30-40 parts by weight of the mixture and have a particle size of approximately less than 850 μm. The stannous oxide may include approximately 55-65 parts by weight of the mixture and have a particle size of approximately less than 150 μm. The aluminum may include approximately 5-10 parts by weight of the mixture and have a particle size of approximately less than 45 μm. The mixture is devoid of zinc chloride. |
FILED | Friday, September 30, 2016 |
APPL NO | 15/282109 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 33/02 (20130101) Original (OR) Class Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 5/00 (20130101) F17C 2221/03 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 9/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131638 | Caruana et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Patrick A. Caruana (LaPlata, Maryland); Alfred G. Stern (Upper Marlboro, Maryland); Alex J. Zaita (Houston, Texas); Thao Vo (Portland, Oregon) |
ABSTRACT | A synthesis for an azo intermediate, 5,5′-azobis(4-chloropyrimidine) is disclosed. 5,5′-azobis(4-chloropyrimidine) is a relatively stable azo compound in that decomposition does not occur until about 194° C. 5,5′-azobis(4-chloropyrimidine) is a product of oxidative dimerization of 5-amino-4-pyrimidine, which a water soluble compound. The azo intermediate is formed in an aqueous solution, but the azo intermediate is substantially insoluble in water; and as it forms it separates producing a reaction mixture that is a slurry. The azo intermediate is isolated by filtration. The azo intermediate is marginally soluble in acetone. The yield is at least 18%, and the oxidizing agent (bleach) is inexpensive, reaction conditions do not require extreme heat or cold, which taken together make the azo intermediate suitable for scaling up. |
FILED | Monday, March 12, 2018 |
APPL NO | 15/932514 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 239/42 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131701 | Rozanov et al. |
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FUNDED BY |
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APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon); SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
INVENTOR(S) | Dmitri Rozanov (Lake Oswego, Oregon); Alexander Aleshin (La Jolla, California) |
ABSTRACT | Disclosed are recombinant polypeptides that include human TRAIL sequences as well as human leucine zipper motifs as well as polynucleotides that encode the recombinant polypeptides, expression vectors that comprise the polynucleotides, pharmaceutical compositions comprising the polypeptides, and methods of using the pharmaceutical compositions for the treatment of cancer. Further disclosed are TRAIL sequences with stabilizing mutations and methods of expressing the disclosed polypeptides in E. coli. |
FILED | Friday, March 25, 2016 |
APPL NO | 15/081300 |
ART UNIT | 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/52 (20130101) Original (OR) Class C07K 14/715 (20130101) C07K 14/4705 (20130101) C07K 2319/73 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131704 | Marasco et al. |
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FUNDED BY |
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APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts); Xiangchun Tang (West Roxbury, Massachusetts) |
ABSTRACT | The present invention provides antibodies that neutralize MERS-CoV and methods of use thereof. The invented antibody is used to treat MERS-CoV infections and symptoms thereof. |
FILED | Monday, April 27, 2015 |
APPL NO | 15/306617 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/507 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/13 (20130101) C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2319/40 (20130101) C07K 2319/43 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16043 (20130101) C12N 2770/20022 (20130101) C12N 2810/609 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2469/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131745 | Thayumanavan et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Sankaran Thayumanavan (Amherst, Massachusetts); Rajasekhar R. Ramireddy (Amherst, Massachusetts) |
ABSTRACT | The invention generally relates to novel polymers and polymeric nanogels having biodegradable polymeric backbones, and compositions and methods of preparation and use thereof, for example, as guest-host polymer nano-assemblies and nano-delivery vehicles, which offer utilities in diverse fields including drug delivery, diagnostics and specialty materials. |
FILED | Thursday, December 14, 2017 |
APPL NO | 15/841388 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5146 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) C08G 69/26 (20130101) C08G 69/48 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131989 | Perez de Leon |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Ignacio Maria Perez de Leon (Dunkirk, Maryland) |
ABSTRACT | A method includes providing a substrate including a tube with a first opening a second opening, depositing a metal film onto a portion of the tube near the first opening, and growing a carbon nanotube by passing a carbon-based gas through the tube and metal film. The gas enters the tube through the second opening and exits the tube through the first opening. |
FILED | Thursday, March 17, 2016 |
APPL NO | 15/072386 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/70 (20130101) B01J 27/00 (20130101) B01J 37/0217 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/162 (20170801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) Original (OR) Class C23C 16/045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132181 | Cowan et al. |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Curtis C. Cowan (E. Hampton, Connecticut); Jorge I. Farah (Hartford, Connecticut) |
ABSTRACT | A method for cooling a rotatable nozzle includes rotating a curved seal about a seal land while maintaining contact therewith. Cooling air is directed through a first diffusion hole in the curved seal to cool the nozzle if the rotatable curved seal is in a first position where higher heat is encountered. Cool air is directed through a second diffusion hole in the curved seal to cool the nozzle if the rotatable curved seal is in a first position where higher heat is encountered and if in a second position where relatively lower heat is encountered. |
FILED | Monday, January 22, 2018 |
APPL NO | 15/876602 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) F01D 11/005 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Jet-propulsion Plants F02K 1/006 (20130101) F02K 1/12 (20130101) F02K 1/822 (20130101) F02K 1/1223 (20130101) Pistons; Cylinders; Sealings F16J 15/025 (20130101) F16J 15/027 (20130101) F16J 15/0893 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/675 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132191 | Surace et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Raymond Surace (Newington, Connecticut); Eric A. Hudson (Harwinton, Connecticut) |
ABSTRACT | A variable area turbine arrangement according to an exemplary aspect of the present disclosure includes, among other things, a variable vane assembly and a secondary flow system associated with the variable vane assembly. Flow modulation of a cooling fluid through the secondary flow system is changed simultaneously with actuation of the variable vane assembly. |
FILED | Wednesday, August 13, 2014 |
APPL NO | 14/912476 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/065 (20130101) F01D 11/24 (20130101) F01D 17/16 (20130101) F01D 17/162 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/12 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132193 | Blaney et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Ken F. Blaney (Middleton, New Hampshire); Michael S. Stevens (Alfred, Maine) |
ABSTRACT | A duct assembly according to an exemplary aspect of the present disclosure includes, among other things, a casing body that extends between a flange and a wall, a first discrete cooling passage formed in the casing body and a second discrete cooling passage circumferentially spaced from the first discrete cooling passage. At least one of the first discrete cooling passage and the second discrete cooling passage includes an axial portion and a tangential portion configured to turn a cooling fluid communicated in each of the first and second discrete cooling passages. |
FILED | Wednesday, August 13, 2014 |
APPL NO | 14/911287 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/081 (20130101) F01D 5/082 (20130101) F01D 9/02 (20130101) F01D 25/12 (20130101) Original (OR) Class F01D 25/14 (20130101) F01D 25/24 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 6/08 (20130101) F02C 7/18 (20130101) Non-positive-displacement Pumps F04D 29/584 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2260/14 (20130101) F05D 2260/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132196 | Wong et al. |
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FUNDED BY |
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APPLICANT(S) | Joey Wong (Enfield, Connecticut); Peter Chen (Manchester, Connecticut); Dana P. Stewart (Vernon, Connecticut); David N. Waxman (Manchester, Connecticut); Michael A. Mike (South Windsor, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Joey Wong (Enfield, Connecticut); Peter Chen (Manchester, Connecticut); Dana P. Stewart (Vernon, Connecticut); David N. Waxman (Manchester, Connecticut); Michael A. Mike (South Windsor, Connecticut) |
ABSTRACT | Gas turbine engine systems involving I-beam struts are provided. In this regard, a representative strut assembly for a gas turbine engine includes a first I-beam strut having first and second flanges spaced from each other and interconnected by a web, the first strut exhibiting a twist along a length of the web. |
FILED | Friday, June 29, 2012 |
APPL NO | 13/538530 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/065 (20130101) F01D 25/162 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132604 | Chamberlain et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Keith Chamberlain (Waldorf, Maryland); Lee Foltz (Indian Head, Maryland); Angel Diaz (Indian Head, Maryland) |
ABSTRACT | A cap for an explosive water charge includes a top surface and a generally cylindrical portion extending downwardly from the top surface. On the outer surface of the generally cylindrical portion are rings and cantilevered, pointed rectangles that enable a water tight fit in the neck of a drinking bottle. The cap is configured to hold a detonator, such as a blasting cap, and two different sizes of tubes of energetic material. |
FILED | Thursday, January 25, 2018 |
APPL NO | 15/932014 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 39/12 (20130101) B65D 41/28 (20130101) B65D 47/06 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/26 (20130101) F42B 33/062 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132752 | Ng et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Kin Chiu Ng (Fresno, California); Subrata Sanyal (Eastvale, California) |
ABSTRACT | A hand-held biosensor including a housing having a lower handgrip portion and an upper target portion extending substantially perpendicular to the lower handgrip portion. An electromagnetic radiation emitter is received within the lower handgrip portion for emitting a laser beam toward a band pass filter received within the upper target portion. The band pass filter is configured to reflect the laser beam toward a target, and to permit passage therethrough of fluorescence emissions from the target. A photo-detector is received within the upper target portion of the housing and is configured to receive the fluorescence emissions from the target. A signal display is configured to provide an indication of fluorescence spectral data from the photo-detector. An adapter may be releasably coupled to the upper target portion of the housing for receiving atmospheric air. |
FILED | Thursday, September 21, 2017 |
APPL NO | 15/712122 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3103 (20130101) G01N 21/6402 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 2021/174 (20130101) G01N 2021/392 (20130101) G01N 2030/0095 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132775 | Santiago et al. |
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FUNDED BY |
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APPLICANT(S) | Juan G. Santiago (Stanford, California); Alexandre Persat (Metuchen, New Jersey); Giancarlo Garcia (Stanford, California); Charbel Eid (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Juan G. Santiago (Stanford, California); Alexandre Persat (Metuchen, New Jersey); Giancarlo Garcia (Stanford, California); Charbel Eid (Stanford, California) |
ABSTRACT | Techniques for enhanced isotachophoresis assays using additives with spatial gradients include forming a concentration gradient of an additive along a channel from an input port to an output port. The channel is used for isotachophoresis with ions of a leading electrolyte having a first mobility greater than a mobility of an analyte, and ions of a trailing electrolyte having a second mobility less than the mobility of the analyte. The additive is different from both the leading electrolyte and the trailing electrolyte; and the additive has a third mobility that assures the analyte will encounter the additive. The method further comprises introducing a mixture of the trailing electrolyte and a sample including the analyte. The method further comprises applying an electric field to the channel; and, measuring the analyte. |
FILED | Monday, August 17, 2015 |
APPL NO | 14/828487 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) G01N 27/44721 (20130101) G01N 27/44756 (20130101) Original (OR) Class G01N 27/44795 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132777 | Clowers et al. |
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FUNDED BY |
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APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
ASSIGNEE(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
INVENTOR(S) | Brian H. Clowers (Pullman, Washington); William F. Siems (Spokane, Washington) |
ABSTRACT | The methods herein provide for analysis of ion populations. Certain aspects include: obtaining a first data set that includes: a first binary On-OFF frequency sweep across a range of frequencies resulting in a first raw data in the time domain and obtaining a second data set that includes: a second binary On-OFF frequency sweep 180° out of phase from the first binary On-OFF frequency sweep so as to result in a second raw data in the time domain from received ion current resulting from the second binary On-OFF frequency sweep. Thereafter the two data sets are combined to provide for raw mobility signals of the ion populations in the time domain for each m/z over a range of selected m/z values. Additional aspects include a hybrid system for performing the methods disclosed herein. |
FILED | Thursday, September 15, 2016 |
APPL NO | 15/266545 |
ART UNIT | 2862 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0027 (20130101) H01J 49/0036 (20130101) H01J 49/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132783 | Gianchandani et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Yogesh B. Gianchandani (Ann Arbor, Michigan); Yutao Qin (Ann Arbor, Michigan) |
ABSTRACT | A method is presented for fabricating a fluidic system for a gas chromatograph. The method includes: microfabricating a portion of a fluidic system of a gas chromatograph on a substrate using a first mask; microfabricating a portion of the fluidic system of the gas chromatograph using a second mask; and microfabricating a portion of the fluidic system of the gas chromatograph using a third mask, such that the first mask, the second mask and the third mask are different from each other and the microfabricating of the fluidic system of the gas chromatograph is completed using only the first, second and third masks. A gas chromatograph wherein a microfabricated Knudsen pump is arranged to operate in a first direction to draw carrier gas into a preconcentrator and in a second direction to draw gas out of the preconcentrator. |
FILED | Friday, May 16, 2014 |
APPL NO | 14/890771 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 2200/12 (20130101) B01L 2300/0887 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/08 (20130101) G01N 30/32 (20130101) G01N 30/88 (20130101) G01N 30/6095 (20130101) Original (OR) Class G01N 2030/025 (20130101) G01N 2030/085 (20130101) G01N 2030/326 (20130101) G01N 2030/328 (20130101) G01N 2030/8881 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132788 | Papenmeier et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Douglas M. Papenmeier (Bloomington, Indiana); Steven M. Lovejoy (Sebastopol, California); Henry Ye (San Mateo, California) |
ABSTRACT | Various methods for separating a metal from its metal oxide for analysis are provided. For example, exemplary methods include approaches for providing a process for separating a metal from its water-soluble metal oxide in a pyrotechnic composition. Exemplary embodiments include a method of separation that allows for analysis of both metal and metal oxide using an elemental analysis technique, (e.g., inductively coupled plasma optical emission spectrometry (ICP-OES)) and determination of the relative amount of elemental metal and its oxide known as speciation. |
FILED | Friday, September 09, 2016 |
APPL NO | 15/261769 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 1/4077 (20130101) G01N 21/73 (20130101) G01N 33/20 (20130101) Original (OR) Class G01N 33/227 (20130101) G01N 2001/4088 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132808 | Boss et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Pamela A. Boss (San Diego, California); Kara C. Sorensen (San Diego, California); Robert D. George (San Diego, California); Anna Y. Obraztsova (San Diego, California); Jonathon K. Oiler (Fort Collins, Colorado) |
ABSTRACT | A method uses flow cytometry to prepare surface enhanced Raman scattering (SERS) substrates for obtaining SERS spectra of bacteria. The method involves using a flow cytometer to sort bacterial cells into populations of bacterial cells based upon their biophysical characteristics. The cells may then be washed with a borate buffer to remove any chemical species that degrade the SERS response. A colloid-coated bacteria suspension is then created by mixing one of the populations of bacterial cells with SERS-active colloidal particles. The colloid-coated bacteria suspension is incubated until the SERS-active colloidal particles partition through the capsule and bind to the cell wall for each bacterial cell in the colloid-coated bacteria suspension. The colloid-coated bacteria suspension is then disposed onto a filter and a SERS spectra of the colloid-coated bacteria suspension is obtained using a Raman spectrometer. |
FILED | Friday, September 23, 2016 |
APPL NO | 15/274599 |
ART UNIT | 1677 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1456 (20130101) G01N 15/1459 (20130101) G01N 21/658 (20130101) G01N 33/56911 (20130101) Original (OR) Class G01N 2001/4088 (20130101) G01N 2015/0065 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132848 | Kure et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Josue Kure (Bloomington, Indiana); Timothy Gomez (Bloomington, Indiana); Patrick Arvin (Loogootee, Indiana) |
ABSTRACT | A system and method for tuning a transformer is provided. A transformer fixture may connect a switching network to a plurality of inductors of a transformer. At least one computing device may calculate a target number of turns for a primary coil and a secondary coil of the transformer based on a frequency response of the transformer. The switching network may connect the inductors of the transformer together in a pattern that results in the primary coil and secondary coil having the target number of turns. |
FILED | Tuesday, April 03, 2018 |
APPL NO | 15/944712 |
ART UNIT | 2864 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 23/00 (20130101) G01R 27/02 (20130101) G01R 29/20 (20130101) Original (OR) Class G01R 31/027 (20130101) G01R 35/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 21/12 (20130101) H01F 27/42 (20130101) H01F 38/28 (20130101) H01F 2029/143 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132880 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secratary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secratary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Connie H. Li (Alexandria, Virginia); Olaf M. J. van 't Erve (Falls Church, Virginia); Jeremy T. Robinson (Washington, District of Columbia); Ying Liu (Waterloo, Canada); Lian Li (Milwaukee, Wisconsin); Berend T. Jonker (Waldorf, Maryland) |
ABSTRACT | A method for directly electrically generating and detecting spin polarization in topological insulators comprising depositing a first and fourth contact on a layer of Bi2Se3 and applying a current between the contacts, which creates a net spin polarization due to spin-momentum locking. A second (comprising ferromagnet/tunnel barrier) and third contact are deposited for detecting the spin polarization. A device for directly electrically generating and detecting the current-generated spin polarization in topological insulators, comprising a first and fourth contact on a layer of Bi2Se3 and a second contact comprising a ferromagnet/oxide tunnel barrier contact as a detector, and a third contact comprising nonmagnetic metal as a reference contact, a current to the first and fourth contact to produce a net spin polarization, and the spin polarization manifesting as a voltage between the second (magnetic) and third (reference) contacts. |
FILED | Friday, November 06, 2015 |
APPL NO | 14/934240 |
ART UNIT | 2868 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/096 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133000 | Sanghera et al. |
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FUNDED BY |
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APPLICANT(S) | Jasbinder S. Sanghera (Ashburn, Virginia); Catalin M Florea (Washington, District of Columbia); Leslie Brandon Shaw (Woodbridge, Virginia); Lynda E Busse (Alexandria, Virginia); Ishwar D. Aggarwal (Charlotte, North Carolina); Steven R. Bowman (Edgewater, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jasbinder S. Sanghera (Ashburn, Virginia); Catalin M Florea (Washington, District of Columbia); Leslie Brandon Shaw (Woodbridge, Virginia); Lynda E Busse (Alexandria, Virginia); Ishwar D. Aggarwal (Charlotte, North Carolina); Steven R. Bowman (Edgewater, Maryland) |
ABSTRACT | An optical system having two or more different optical elements with a corresponding interface between the optical elements. At least one of the optical elements has an anti-reflective structure that is transferred to the interface between two optical elements, typically by embossing. Also disclosed is the related method for making the optical system. |
FILED | Friday, September 28, 2012 |
APPL NO | 13/629648 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/118 (20130101) G02B 6/25 (20130101) Original (OR) Class G02B 6/32 (20130101) G02B 6/255 (20130101) G02B 6/262 (20130101) G02B 6/4207 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133039 | Gibson et al. |
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APPLICANT(S) | Daniel J. Gibson (Cheverly, Maryland); Mikhail Kotov (Silver Spring, Maryland); Geoff Chin (Arlington, Virginia); Shyam S. Bayya (Ashburn, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Vinh Q. Nguyen (Fairfax, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Daniel J. Gibson (Cheverly, Maryland); Mikhail Kotov (Silver Spring, Maryland); Geoff Chin (Arlington, Virginia); Shyam S. Bayya (Ashburn, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Vinh Q. Nguyen (Fairfax, Virginia) |
ABSTRACT | A method for making a gradient index infrared transmitting optic by thermally treating a preform, where the preform comprises two or more infrared transmitting glasses having different compositions and optical properties, where there is an interface between adjacent glasses, where during the thermal treatment one or more chemical elements from the glasses diffuses through one or more interface resulting in a diffused gradient index optical element comprising a gradient in the chemical element concentration, and where the optical element has a gradient in refractive index and dispersion. Also disclosed is the related infrared transmitting optical element made by this method. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/210868 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) C03C 3/323 (20130101) C03C 4/10 (20130101) C03C 23/007 (20130101) Optical Elements, Systems, or Apparatus G02B 3/0087 (20130101) G02B 13/146 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133149 | Timurdogan et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Erman Timurdogan (Cambridge, Massachusetts); Michael R. Watts (Hingham, Massachusetts) |
ABSTRACT | A waveguide includes an array of p-i-n junctions formed by ions implanted into the waveguide. The p-i-n junctions concentrate electric fields applied on the waveguide to convert the third order susceptibility χ(3) into the second order susceptibility χ(2) and induce the DC Kerr effect. The periodic electrical fields concentrated by the p-i-n junctions effectively create a wave vector, which together with the wave vectors of optical beams in the waveguide satisfies phase matching conditions for nonlinear optical effects. The phase matching can significantly enhance the efficiency of the nonlinear optical effects, such as second harmonic generation, sum frequency generation, difference frequency generation, and four-wave mixing. Waveguides with arrays of PIN junctions can also be used in phase modulators, amplitude modulators, and filters. |
FILED | Tuesday, November 22, 2016 |
APPL NO | 15/359149 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) G02B 2006/12061 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) Original (OR) Class G02F 1/377 (20130101) G02F 1/3534 (20130101) G02F 1/3544 (20130101) G02F 1/3556 (20130101) G02F 2001/3548 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133983 | Chelian et al. |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Suhas E. Chelian (Encino, California); Stephanie E. Goldfarb (Santa Monica, California); Rajan Bhattacharyya (Sherman Oaks, California) |
ABSTRACT | Described is system for modeling probability matching and loss sensitivity among human subjects. A set of features related to probability matching and loss sensitivity is extracted from collected human responses. The set of features are processed with a genetic algorithm to fit the collected human responses with a set of neural network model instances. A set of model parameters are generated from the genetic algorithm and used to generate at least one of an explanatory and predictive model of human behavior. |
FILED | Wednesday, April 22, 2015 |
APPL NO | 14/693485 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/126 (20130101) G06N 7/005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133986 | Newton et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Charles Newton (Jacksonville, Florida); Osama Nayfeh (San Diego, California); Kenneth Simonsen (San Diego, California) |
ABSTRACT | A device includes a converter configured to convert photons input from a photonic link into Cooper-pairs, a first superconductor, a second superconductor, a plurality of nanowires connected to the first superconductor and the second superconductor, and a gate array connected to the plurality of nanowires and configured to alter quantum states of ions within the plurality of nanowires. |
FILED | Tuesday, January 30, 2018 |
APPL NO | 15/883158 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) Pulse Technique H03K 19/195 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134181 | Black et al. |
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FUNDED BY |
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APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
INVENTOR(S) | Michael J. Black (Tuebingen, Germany); Peng Guan (Mountain View, California) |
ABSTRACT | A system generates a clothing deformation model which models one or more of a pose-dependent clothing shape variation which is induced by underlying body pose parameters, a pose-independent clothing shape variation which is induced by clothing size and underlying body shape parameters and a clothing shape variation including a combination of the pose-dependent clothing shape variation and/or the pose-independent clothing shape variation. The system generates, for an input human body, a custom-shaped garment associated with a clothing type by mapping, via the clothing deformation model, body shape parameters of the input human body to clothing shape parameters of the clothing type and dresses the input human body with the custom-shaped garment. |
FILED | Monday, June 12, 2017 |
APPL NO | 15/620614 |
ART UNIT | 2617 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 17/5009 (20130101) G06F 2217/32 (20130101) Image Data Processing or Generation, in General G06T 17/00 (20130101) Original (OR) Class G06T 19/20 (20130101) G06T 2210/16 (20130101) G06T 2219/2016 (20130101) G06T 2219/2021 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134434 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Woo K. Lee (Washington, District of Columbia); Keith E. Whitener (Washington, District of Columbia); Paul E. Sheehan (Springfield, Virginia) |
ABSTRACT | A method of making magnetic graphene comprising transferring or growing a graphene film on a substrate, functionalizing the graphene film, hydrogenating the graphene film and forming fully hydrogenated graphene, manipulating the extent of the hydrogen content, and forming areas of magnetic graphene and non-magnetic graphene. A ferromagnetic graphene film comprising film that has a thickness of less than two atom layers thick. |
FILED | Tuesday, October 20, 2015 |
APPL NO | 14/918328 |
ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 5/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0446 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 5/65 (20130101) G11B 5/84 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134972 | Oliver et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | William D. Oliver (Arlington, Massachusetts); Andrew J. Kerman (Arlington, Massachusetts); Rabindra N. Das (Lexington, Massachusetts); Donna-Ruth W. Yost (Acton, Massachusetts); Danna Rosenberg (Arlington, Massachusetts); Mark A. Gouker (Belmont, Massachusetts) |
ABSTRACT | A cryogenic quantum bit package with multiple qubit circuits facilitates inter-qubit signal propagation using a multi-chip module (MCM). Multiple qubits are grouped within the package into one or more qubit integrated circuits (ICs). The qubit ICs themselves are electrically coupled to each other via a structure including a superconducting MCM and superconducting interconnects. Coupling of quantum electrical signals between a qubit and other qubits, a substrate, or the MCM uses a coupler circuit, such as a Josephson junction, capacitor, inductor, or resonator. |
FILED | Thursday, November 03, 2016 |
APPL NO | 15/342589 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 99/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/0657 (20130101) H01L 27/18 (20130101) H01L 39/025 (20130101) H01L 39/223 (20130101) Original (OR) Class H01L 2224/16225 (20130101) H01L 2924/15192 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134979 | Kawakami et al. |
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FUNDED BY |
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APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
INVENTOR(S) | Roland K. Kawakami (Columbus, Ohio); Simranjeet Singh (Columbus, Ohio); Jyoti Katoch (Columbus, Ohio) |
ABSTRACT | A spintronic device is disclosed. The spintronic device includes a spin current transport layer, a spin injector, and a spin detector. The spin injector includes a first tunnel barrier layer made of strontium oxide (SrO) disposed over the spin current transport layer and a first magnetic material layer disposed over the first tunnel barrier layer. The spin detector includes a second tunnel barrier layer made of SrO disposed over the spin current transport layer. A second magnetic material layer is disposed over the second tunnel barrier layer and a spin sensor has a sensor input terminal coupled to the second magnetic material layer. |
FILED | Friday, June 23, 2017 |
APPL NO | 15/631825 |
ART UNIT | 2825 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 11/161 (20130101) G11C 11/1673 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/16 (20130101) H01F 10/3204 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/08 (20130101) H01L 43/10 (20130101) Original (OR) Class Pulse Technique H03K 19/16 (20130101) H03K 19/21 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135227 | Wunderer et al. |
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FUNDED BY |
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APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Thomas Wunderer (Palo Alto, California); Noble M. Johnson (Menlo Park, California) |
ABSTRACT | An ultraviolet (UV) radiation emitting device includes an epitaxial heterostructure comprising an AlGaInN active region. The AlGaInN active region includes one or more quantum well structures with Al content greater than about 50% and having a non-c-plane crystallographic growth orientation. The AlGaInN active region is configured to generate UV radiation in response to excitation by an electron beam generated by an electron beam pump source. |
FILED | Friday, May 19, 2017 |
APPL NO | 15/600569 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/04 (20130101) H01S 5/125 (20130101) H01S 5/3202 (20130101) Original (OR) Class H01S 5/34333 (20130101) H01S 2304/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135236 | Schill, Jr. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Nevada System of Higher Education on behalf of the University of Nevada (Las Vegas, Nevada) |
ASSIGNEE(S) | The Board of Regents of the Nevada Systems of Higher Education on Behalf of the University of Nevada, Las Vegas (Las Vegas, Nevada) |
INVENTOR(S) | Robert A. Schill, Jr. (Henderson, Nevada) |
ABSTRACT | Methods and systems for preventing direct and indirect electronic attacks, cyber attacks, and/or minimizing the impact of high voltage pulses are disclosed. In an aspect, an example system can comprise an electromagnetic plasma disrupter device. The electromagnetic plasma disrupter device can comprise a gas pressurized enclosure such a waveguide, grounded metal enclosure, or Faraday shield having a first pair of opposed electrodes at least partially enclosed in the enclosure. A first electrode of a first pair of the opposed electrodes can be connected to ground. A second electrode of the first pair of opposed electrodes can be coupled to a voltage source. The system can optionally comprise a second pair of opposed electrodes. The second pair of electrodes can allow, under normal operation, for signals to enter and leave an electronic circuit that is being protected. |
FILED | Thursday, February 20, 2014 |
APPL NO | 14/185871 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Emergency Protective Circuit Arrangements H02H 5/005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135366 | Pais |
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FUNDED BY |
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APPLICANT(S) | Salvatore Pais (Leonardtown, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Salvatore Pais (Leonardtown, Maryland) |
ABSTRACT | The electromagnetic field generator includes a shell, an electrostatic generator, a power plant, a thermoelectric generator, and an electric motor. The shell has embedded polycrystalline ferroelectric ceramic material which is polarized such that the ceramic material exhibits strong Piezoelectric Effect properties thus inducing high frequency vibrations. The shell may be further doped with radioactive elements which under high frequency vibrations induce gamma ray emission. The electrostatic generator is for charging up the shell and is disposed within the shell. The power plant is to generate thermal power, and is disposed within the sphere. The thermoelectric generator is to convert the thermal power generated by the power plant to electrical energy. The electric motor powered by the electrical energy generated by the thermoelectric generator, and supplies input voltage such that the shell spins at high angular speeds, vibrates at high frequencies, and generates an electromagnetic field. |
FILED | Friday, July 24, 2015 |
APPL NO | 14/807943 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/52 (20130101) B64G 1/66 (20130101) B64G 9/00 (20130101) Electric Machines Not Otherwise Provided for H02N 11/002 (20130101) Original (OR) Class H02N 99/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135471 | Stanley-Marbell et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Phillip Stanley-Marbell (Boston, Massachusetts); Martin C. Rinard (Arlington, Massachusetts) |
ABSTRACT | A communication system receives a binary sequence from a sensor, identifies a power consuming characteristic of the binary sequence, and determines an error component configured to reduce the power consuming characteristic of the binary sequence. The system compares the error component to an error tolerance deviation, and if the error component is below the error tolerance deviation, combines the error component with the binary sequence to produce an output sequence and transmits the output sequence via a serial interface to a receiver configured to receive the output sequence. The error threshold is based in part on an error tolerance characteristic of the receiver. |
FILED | Friday, June 02, 2017 |
APPL NO | 15/612485 |
ART UNIT | 2631 — Digital Communications |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 7/00 (20130101) H03M 7/14 (20130101) Transmission H04B 1/02 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 1/009 (20130101) H04L 1/0042 (20130101) Pictorial Communication, e.g Television H04N 19/156 (20141101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135539 | Moss et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Benjamin Roy Moss (Brookline, Massachusetts); Jason Scott Orcutt (Somerville, Massachusetts); Vladimir Marko Stojanovic (Lexington, Massachusetts) |
ABSTRACT | Devices and techniques for integrated optical data communication. A method of encoding symbols in an optical signal may include encoding a first symbol by injecting charge carriers, at a first rate, into a semiconductor device, such as a PIN diode. The method may also include encoding a second symbol by injecting charge carriers, at a second rate, into the semiconductor device. The first rate may exceed the second rate. A modulator driver circuit may include a resistive circuit coupled between supply terminal and drive terminals. The modulator driver circuit may also include a control circuit coupled between a data terminal and the resistive circuit. The control circuit may modulate a resistance of the resistive circuit by selectively coupling one or more of a plurality of portions of the resistive circuit to the drive terminal based on data to be optically encoded. In some embodiments, a modulator driver circuit and an optical modulator may be integrated on the same die or stacked (3D integrated) die and connected with through-oxide or through-silicon vias. |
FILED | Friday, February 15, 2013 |
APPL NO | 14/436613 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0121 (20130101) G02F 1/0123 (20130101) G02F 2203/15 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/823437 (20130101) H01L 31/18 (20130101) H01L 31/105 (20130101) Transmission H04B 10/516 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135708 | Dinan et al. |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | James Dinan (Hudson, Massachusetts); David Keppel (Seattle, Washington) |
ABSTRACT | Technologies for monitoring communication performance of a high performance computing (HPC) network include a performance probing engine of a source endpoint node of the HPC network. The performance probing engine is configured to generate a probe request that includes a timestamp of the probe request and transmit the probe request to a destination endpoint node of the HPC network communicatively coupled to the source endpoint node via the HPC network. The performance probing engine is additionally configured to receive a probe response from the destination endpoint node via the HPC network and to generate another timestamp that corresponds to the probe request having been received. Further, the performance probing engine is configured to determine a round-trip latency as a function of the probe request and probe response timestamps. Other embodiments are described and claimed. |
FILED | Friday, September 25, 2015 |
APPL NO | 14/866536 |
ART UNIT | 2441 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/10 (20130101) H04L 43/0876 (20130101) Original (OR) Class H04L 67/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135711 | Zak et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Robert C. Zak (Bolton, Massachusetts); David Keppel (Mountain View, California); James Dinan (Hudson, Massachusetts) |
ABSTRACT | Technologies for tracing network performance include a network computing device configured to receive a network packet from a source endpoint node, process the received network packet, capture trace data corresponding to the network packet as it is processed by the network computing device, and transmit the received network packet to a target endpoint node. The network computing device is further configured to generate a trace data network packet that includes at least a portion of the captured trace data and transmit the trace data network packet to the destination endpoint node. The destination endpoint node is configured to monitor performance of the network by reconstructing a trace of the network packet based on the trace data of the trace data network packet. Other embodiments are described herein. |
FILED | Tuesday, December 22, 2015 |
APPL NO | 14/979140 |
ART UNIT | 2464 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/04 (20130101) H04L 43/028 (20130101) H04L 43/106 (20130101) Original (OR) Class H04L 43/0876 (20130101) H04L 45/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10136083 | Veeder |
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FUNDED BY |
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APPLICANT(S) | Senseeker Engineering Inc. (Goleta, California) |
ASSIGNEE(S) | Senseeker Engineering Inc. (Goleta, California) |
INVENTOR(S) | Kenton Veeder (Santa Barbara, California) |
ABSTRACT | The present disclosure provides a delta-sigma modulator circuit for use in a pixelated image sensor or a readout integrated circuit. In one aspect, the modulator circuit includes a dynamic resistance element configured to have a variable resistance that changes in accordance with a voltage difference across the dynamic resistance element. |
FILED | Monday, February 27, 2017 |
APPL NO | 15/443968 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Pictorial Communication, e.g Television H04N 5/378 (20130101) H04N 5/3577 (20130101) Original (OR) Class H04N 5/37455 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10136529 | McPherson et al. |
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FUNDED BY |
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APPLICANT(S) | Cree Fayetteville, Inc. (Fayetteville, Arkansas) |
ASSIGNEE(S) | Cree Fayetteville, Inc. (Fayetteville, Arkansas) |
INVENTOR(S) | Brice McPherson (Fayetteville, Arkansas); Peter Killeen (Fayetteville, Arkansas); Alex Lostetter (Fayetteville, Arkansas); Robert Shaw (Fayetteville, Arkansas); Brandon Passmore (Fayetteville, Arkansas); Jared Hornberger (Fayetteville, Arkansas); Tony M. Berry (Springdale, Arkansas) |
ABSTRACT | A method of making a power module includes providing a base plate defining a topology pattern, providing a power substrate above the base plate, providing at least two power contacts and arranging solder catches in the at least two power contacts, soldering the at least two power contacts to the power substrate utilizing the solder catches, and securing a housing to the power substrate. |
FILED | Monday, August 15, 2016 |
APPL NO | 15/236844 |
ART UNIT | 2847 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4817 (20130101) H01L 23/15 (20130101) H01L 23/049 (20130101) H01L 23/3675 (20130101) H01L 23/3735 (20130101) H01L 23/49838 (20130101) H01L 23/49861 (20130101) H01L 25/07 (20130101) H01L 25/072 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0296 (20130101) H05K 5/0013 (20130101) H05K 5/0069 (20130101) Original (OR) Class H05K 5/0091 (20130101) H05K 5/0247 (20130101) H05K 7/20509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10136550 | Chainer et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Fishkill, New York); Fanghao Yang (Somerset, New Jersey) |
ABSTRACT | Techniques that facilitate two-phase liquid cooling of an electronic device are provided. In one example, an apparatus, such as a cold plate device, comprises a first stackable layer and a second stackable layer. The first stackable layer comprises a first channel formed within the first stackable layer. The first channel comprises a first channel length and the first channel receives a coolant fluid via an inlet port of the apparatus. The second stackable layer comprises a second channel that provides a path for the coolant fluid to flow between the first channel and an outlet port of the apparatus. The second channel comprise a second channel length that is different than the first channel length. |
FILED | Friday, September 30, 2016 |
APPL NO | 15/281336 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/367 (20130101) H01L 23/467 (20130101) H01L 23/473 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20254 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10136554 | Chainer et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Timothy Joseph Chainer (Putnam Valley, New York); Pritish Ranjan Parida (Fishkill, New York); Mark Delorman Schultz (Ossining, New York) |
ABSTRACT | Techniques that facilitate two-phase liquid cooling electronics are provided. In one example, a system comprises a pump and a valve. The pump circulates a coolant refrigerant through a two-phase refrigerant system associated with an electronic component. The valve controls a flow path of the coolant refrigerant that flows through the two-phase refrigerant system. Furthermore, the valve modifies the flow path of the coolant refrigerant through the two-phase refrigerant system in response to a determination that an operation of the pump satisfies a defined criterion. |
FILED | Friday, March 31, 2017 |
APPL NO | 15/475700 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Non-positive-displacement Pumps F04D 19/002 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0617 (20130101) G05D 23/1917 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/2029 (20130101) H05K 7/20172 (20130101) H05K 7/20327 (20130101) H05K 7/20381 (20130101) Original (OR) Class H05K 7/20727 (20130101) H05K 7/20809 (20130101) H05K 7/20836 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 10130899 | Pascall et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Andrew J. Pascall (Livermore, California); George R. Farquar (Livermore, California); Christopher M. Spadaccini (Livermore, California); Sarah C. Chinn (Redwood City, California) |
ABSTRACT | A system for separating components of a fluid containing at least a first component and a second component includes a device having an inlet for introducing the fluid into the device, a first outlet for directing the first component of the fluid from the device, and a second outlet for directing the second component of the fluid from the device. A material that has a gradient in properties is located in the device between the inlet and the first and second outlets. The material has a first portion with an affinity for the first fluid component and a second portion with an affinity for the second fluid component. The first portion is positioned with relation to the first outlet such that the first component is directed from said device through the first outlet. The second portion is positioned with relation to the second outlet such that the second component is directed from the device through the second outlet. |
FILED | Thursday, January 17, 2013 |
APPL NO | 13/744270 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 15/18 (20130101) Original (OR) Class B01D 15/22 (20130101) B01D 15/1821 (20130101) B01D 15/1828 (20130101) B01D 15/1842 (20130101) B01D 15/1857 (20130101) B01D 15/1864 (20130101) B01D 15/1885 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130907 | Koech et al. |
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FUNDED BY |
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APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
INVENTOR(S) | Phillip K. Koech (Richland, Washington); Deepika Malhotra (Richland, Washington); David J. Heldebrant (Richland, Washington); Vassiliki-Alexandra Glezakou (Richland, Washington); Roger J. Rousseau (Richland, Washington); David C. Cantu (Richland, Washington) |
ABSTRACT | A class of water lean, organic solvents that can bind with various acid gasses to form acid gas bound molecules having a high degree of intramolecular hydrogen bonding which enables their use as regenerable solvents for acid gas capture. Unlike the other devices described in the prior art, the present invention takes advantage of shortened distances between the portions of the molecule that form hydrogen bonds within the structures when loaded with an acid gas so as to create a molecule with a higher internal bonding affinity and a reduced proclivity for agglomeration with other molecules. |
FILED | Thursday, January 19, 2017 |
APPL NO | 15/410523 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/1425 (20130101) Original (OR) Class B01D 53/1456 (20130101) B01D 53/1493 (20130101) B01D 2252/2041 (20130101) B01D 2252/20426 (20130101) B01D 2252/20431 (20130101) B01D 2252/20457 (20130101) B01D 2257/302 (20130101) B01D 2257/308 (20130101) B01D 2257/504 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130916 | Rempe et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico); THE REGENTS OF THE UNIVERSITY OF NEW MEXICO (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); The Regents of the University of New Mexico (Albuquerque, New Mexico) |
INVENTOR(S) | Susan Rempe (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico); David Michael Rogers (Albuquerque, New Mexico); Ying-Bing Jiang (Albuquerque, New Mexico); Shaorong Yang (Albuquerque, New Mexico) |
ABSTRACT | The present disclosure is directed to biomimetic membranes and methods of manufacturing such membranes that include structural features that mimic the structures of cellular membrane channels and produce membrane designs capable of high selectivity and high permeability or absorptivity. The membrane structure, material and chemistry can be selected to perform liquid separations, gas separation and capture, ion transport and adsorption for a variety of applications. |
FILED | Thursday, September 22, 2016 |
APPL NO | 15/273445 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 63/066 (20130101) B01D 69/105 (20130101) B01D 71/02 (20130101) Original (OR) Class B01D 2323/283 (20130101) B01D 2325/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/02 (20130101) C23C 16/04 (20130101) C23C 16/45555 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10130961 | Keicher et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | David M. Keicher (Albuquerque, New Mexico); Adam Cook (Albuquerque, New Mexico) |
ABSTRACT | Hydrodynamic focusing of two fluid steams provides a novel micro printing technology for printed electronics and other high performance applications. |
FILED | Thursday, November 05, 2015 |
APPL NO | 14/933988 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/06 (20130101) Original (OR) Class B05B 7/066 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/20 (20170801) B29C 64/112 (20170801) B29C 64/209 (20170801) B29C 64/245 (20170801) B29C 64/357 (20170801) B29C 67/0059 (20130101) B29C 67/0085 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2039/06 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131245 | Hand, III et al. |
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FUNDED BY |
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APPLICANT(S) | FORD GLOBAL TECHNOLOGIES, LLC (Dearborn, Michigan) |
ASSIGNEE(S) | FORD GLOBAL TECHNOLOGIES, LLC (Dearborn, Michigan) |
INVENTOR(S) | Michael J. Hand, III (Ypsilanti, Michigan); Richard Dyche Anderson (Plymouth, Michigan) |
ABSTRACT | An electrified vehicle has a battery pack comprising series-connected battery units providing a main voltage. To supply a lower voltage bus equally from all battery units, a plurality of DC/DC converters are powered by respective units and have their outputs in parallel. A central module has an outer loop controller generating a target current to regulate the bus voltage to a predetermined voltage and has an allocator distributing the target current into a plurality of allocated current commands according to respective states of charge of the battery units. A plurality of local controllers each adjusts a current of a respective DC/DC converter. Each local controller receives a respective allocated current command as a respective feedforward control variable. Each local controller uses an error between the bus voltage and the predetermined voltage to be integrated as a respective feedback control variable only when the error is above a threshold. |
FILED | Tuesday, August 16, 2016 |
APPL NO | 15/238003 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/1812 (20130101) B60L 11/1866 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/14 (20130101) H02J 7/008 (20130101) H02J 7/0018 (20130101) H02J 7/0019 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131754 | Stadermann et al. |
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FUNDED BY |
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APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); General Atomics (San Diego, California) |
INVENTOR(S) | Michael Stadermann (Pleasanton, California); Salmaan H. Baxamusa (Livermore, California); William C. Floyd, III (Oakland, California); Philip E. Miller (Livermore, California); Tayyab I. Suratwala (Pleasanton, California); Anatolios A. Tambazidis (Pleasanton, California); Kelly Patricia Youngblood (Livermore, California); Chantel Aracne-Ruddle (Livermore, California); Art J. Nelson (Livermore, California); Maverick Chea (Cypress, California); Shuali Li (Fremont, California) |
ABSTRACT | A method of making large ultrathin free-standing polymer films without use of a sacrificial layer includes the steps of providing a substrate, applying a polyelectrolyte material to said substrate, applying a polymer material onto said substrate and onto said polyelectrolyte material, and directly delaminating said polymer material from said substrate and said polyelectrolyte to produce the ultrathin free-standing polymer film. |
FILED | Friday, April 15, 2016 |
APPL NO | 15/130524 |
ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/36 (20130101) B05D 3/12 (20130101) B05D 3/107 (20130101) B05D 7/24 (20130101) B05D 7/52 (20130101) B05D 7/54 (20130101) B05D 2201/04 (20130101) B05D 2203/30 (20130101) B05D 2350/60 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/06 (20130101) B32B 27/28 (20130101) B32B 43/006 (20130101) B32B 2038/0056 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Original (OR) Class C08J 2325/06 (20130101) C08J 2329/14 (20130101) C08J 2333/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131838 | Berdahl |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Paul H. Berdahl (Walnut Creek, California) |
ABSTRACT | The present invention provides for a composition comprising a pigment, wherein the composition is suitable for coating a surface that is, or is expected to be, exposed to the sun. The pigment comprises particles that fluoresce in sunlight, thereby remaining cooler in the sun than coatings pigmented with non-fluorescent particles. The particles comprise solids that fluoresce or glow in the visible or near infrared (NIR) spectra, or that fluoresce when doped. Suitable dopants include, but are not limited to, ions of rare earths and transition metals. |
FILED | Tuesday, March 31, 2015 |
APPL NO | 14/675328 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/22 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/54 (20130101) C09K 11/562 (20130101) C09K 11/685 (20130101) Original (OR) Class C09K 11/883 (20130101) C09K 11/7704 (20130101) C09K 11/7706 (20130101) C09K 11/7772 (20130101) C09K 11/7774 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131893 | Spodsberg et al. |
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FUNDED BY |
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APPLICANT(S) | Novozymes Inc. (Davis, California) |
ASSIGNEE(S) | Novozymes. Inc. (Davis, California) |
INVENTOR(S) | Nikolaj Spodsberg (Bagsvaerd, Denmark); Tarana Shaghasi (Davis, California) |
ABSTRACT | The present invention relates to isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains. |
FILED | Tuesday, April 25, 2017 |
APPL NO | 15/496805 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Enzymes C12Y 302/01004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131899 | Hansen et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Ryan Robert Hansen (Knoxville, Tennessee); Scott T. Retterer (Knoxville, Tennessee); Bradley Steward Lokitz (Knoxville, Tennessee); Jennifer L. Morrell-Falvey (Knoxville, Tennessee); Juan Pablo Hinestrosa Salazar (San Diego, California); Jamie Michael Messman (Leawood, Kansas); Sidney Michael Kilbey, II (Knoxville, Tennessee); John Francis Ankner (Oak Ridge, Tennessee) |
ABSTRACT | A composition useful for cell capture, the composition comprising a solid substrate on which is affixed a patterned polymer, and a cell-targeting agent attached to said patterned polymer, wherein said cell-targeting agent is exposed. Also described is a method for the preparation of the cell capturing composition, as well as flow through devices in which the cell capturing composition is incorporated. Further described is a method of capturing cells by contacting the cell-capturing composition with a liquid or gaseous sample containing cells. The method for capturing cells may also be a method for testing for the presence of one or more classes or species of cells or cellular organisms in a liquid or gaseous sample. |
FILED | Monday, March 17, 2014 |
APPL NO | 14/215552 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 293/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/06 (20130101) C12N 11/08 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131903 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | Chieh Chang (San Jose, California); Rajiv Bharadwaj (Emeryville, California); Anup K. Singh (Danville, California); Aarthi Chandrasekaran (San Jose, California); Nathan J. Hillson (San Francisco, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Sandia Corporation (Livermore, California) |
INVENTOR(S) | Chieh Chang (San Jose, California); Rajiv Bharadwaj (Emeryville, California); Anup K. Singh (Danville, California); Aarthi Chandrasekaran (San Jose, California); Nathan J. Hillson (San Francisco, California) |
ABSTRACT | This invention provides methods and compositions for assembling biological constructs (e.g., plasmids, transformed cells, etc.). In certain embodiments the methods involve encapsulating separate components of the biological construct each in a fluid droplet confined in a fluid channel; optionally mixing droplets from different fluid channels to form a sequenced order of droplets carrying different components of the biological construct in a channel or chamber; and optionally combining two or more droplets each containing different components of the biological construct to permit the components to react with each other in one or more reactions contributing to the assembly of the biological construct. |
FILED | Monday, April 02, 2012 |
APPL NO | 13/437727 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/66 (20130101) C12N 15/1027 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131991 | Elam et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey W. Elam (Elmhurst, Illinois); Joseph A. Libera (Clarendon Hills, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Jeffrey W. Elam (Elmhurst, Illinois); Joseph A. Libera (Clarendon Hills, Illinois) |
ABSTRACT | A method of preparing light transmitting conducting metal oxide (TCO) films using atomic layer deposition (ALD) of a metal precursor multiple oxidizing reactants. The multiple metal oxidizing reactants may be selected to enhance growth of the TCO film. In a particular embodiment, an indium oxide TCO film is prepared using a cyclopentadienyl indium precursor and a combination of water and oxygen. |
FILED | Thursday, September 30, 2010 |
APPL NO | 12/895305 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/407 (20130101) C23C 16/45527 (20130101) Original (OR) Class C23C 16/45553 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131996 | Kemp et al. |
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FUNDED BY |
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APPLICANT(S) | Richard Kemp (Albuquerque, New Mexico); Diane A. Dickie (Albuquerque, New Mexico); Elizabeth S. Donovan (Albuquerque, New Mexico); Brian Barry (Dubuque, Iowa) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Richard Kemp (Albuquerque, New Mexico); Diane A. Dickie (Albuquerque, New Mexico); Elizabeth S. Donovan (Albuquerque, New Mexico); Brian Barry (Dubuque, Iowa) |
ABSTRACT | Novel complexes of various earth-abundant, inexpensive transition or main group metals that facilitate the transformation of carbon dioxide into other more useful organic products. These complexes can bind and alter the CO2 at mild conditions of temperature and pressure, enabling, according to some embodiments, the electrochemical conversion of CO2 into new products. |
FILED | Tuesday, March 03, 2015 |
APPL NO | 15/123900 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/189 (20130101) B01J 31/1815 (20130101) B01J 2231/625 (20130101) B01J 2531/26 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 3/04 (20130101) Original (OR) Class C25B 11/0405 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132170 | Garcia-Crespo et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Andres Jose Garcia-Crespo (Greenville, South Carolina); Peter de Diego (Saluda, North Carolina) |
ABSTRACT | A system includes a turbomachine blade segment including an airfoil with an exterior surface, and a platform coupled to the airfoil having a first side and a second side. The system also includes a concave fillet transition extending between the airfoil and the platform. The concave fillet transition includes one or more interface ply segments extending across the exterior surface of the airfoil and the first or the second side of the platform to form a continuous surface between the airfoil and the platform. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/842639 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/30 (20130101) Original (OR) Class F01D 5/3007 (20130101) F01D 5/3084 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/80 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132175 | Little |
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FUNDED BY |
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APPLICANT(S) | Siemens Energy, Inc. (Orlando, Florida) |
ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
INVENTOR(S) | David A. Little (Mount Dora, Florida) |
ABSTRACT | An arrangement (10) for delivering gases from combustors (15) to a first row of blades. The arrangement (10) includes at least an upstream flow path (60) including an aft first side wall (64) and a downstream flow path (62) including a forward second side wall (66). A convergence junction trailing edge (40) is defined at a downstream terminal edge (41) of the first side wall (64), and the second side wall (66) converges toward the first side wall (64) in the direction of the convergence junction trailing edge (40). An impingement sheet structure (78) is located between and provides impingement cooling air to the first and second side walls (64, 66). Openings (88) provide a cooling air passage between the first and second side walls (64, 66) and provide a flow of post impingement air into the gas path at the convergence junction trailing edge (40). |
FILED | Tuesday, October 07, 2014 |
APPL NO | 15/509987 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/023 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/12 (20130101) F02C 7/125 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/12 (20130101) F05D 2250/25 (20130101) F05D 2260/201 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/42 (20130101) F23R 3/46 (20130101) F23R 3/425 (20130101) F23R 2900/03044 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132574 | Koplow |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Jeffrey P. Koplow (San Ramon, California) |
ABSTRACT | Systems and methods described herein are directed to rotary heat exchangers configured to transfer heat to a heat transfer medium flowing in substantially axial direction within the heat exchangers. Exemplary heat exchangers include a heat conducting structure which is configured to be in thermal contact with a thermal load or a thermal sink, and a heat transfer structure rotatably coupled to the heat conducting structure to form a gap region between the heat conducting structure and the heat transfer structure, the heat transfer structure being configured to rotate during operation of the device and flow a heat transfer medium in a substantially axial direction through the heat transfer structure. In example devices heat may be transferred across the gap region from a heated axial flow of the heat transfer medium to a cool stationary heat conducting structure, or from a heated stationary conducting structure to a cool axial flow of the heat transfer medium. |
FILED | Wednesday, January 06, 2016 |
APPL NO | 14/989603 |
ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive-displacement Pumps F04D 25/066 (20130101) F04D 25/0606 (20130101) F04D 25/0613 (20130101) F04D 29/582 (20130101) F04D 29/5853 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/0016 (20130101) F28D 15/025 (20130101) F28D 15/0208 (20130101) F28D 15/0233 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/02 (20130101) F28F 13/02 (20130101) F28F 13/12 (20130101) Original (OR) Class F28F 13/125 (20130101) F28F 2215/06 (20130101) F28F 2250/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/467 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20163 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132699 | Pillars et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Jamin Ryan Pillars (Albuquerque, New Mexico); Eric Langlois (Albuquerque, New Mexico); Christian Lew Arrington (Albuquerque, New Mexico); Todd Monson (Albuquerque, New Mexico) |
ABSTRACT | The present invention relates to magnetoelastic resonators, sensors, and tunable devices, as well as methods for making such components. The resonators can be used as tags and/or sensors. In general, the resonators include one or more micron-sized resonator portions affixed on a substrate. For use as a tag, each tag includes a plurality of resonator portions that allow for multiplexed coding, and methods for making tags and arrays of such tags include use of electrodeposition processes. In particular embodiments, these components include an electrodeposited material that exhibits magnetostrictive properties. |
FILED | Tuesday, October 06, 2015 |
APPL NO | 14/876652 |
ART UNIT | 2827 — Semiconductors/Memory |
CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/562 (20130101) C25D 5/02 (20130101) C25D 5/18 (20130101) C25D 7/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/125 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132781 | Steingart et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Daniel Artemus Steingart (Princeton, New Jersey); Shoham Bhadra (North Brunswick, New Jersey); Andrew Hsieh (Princeton, New Jersey); Benjamin Hertzberg (Princeton, New Jersey); Peter James Gjeltema (Stow, Massachusetts); Clarence Worth Rowley, III (Princeton, New Jersey); Alexandre S. R. Goy (Lawrenceville, New Jersey); Jason Wolf Fleischer (Princeton, New Jersey) |
ABSTRACT | A method, an apparatus and a system for interrogating a battery in order to determine one or more of: (i) its state of charge (SOC), (ii) its state of health (SOH), (iii) physical state of one or more internal components or parts, which utilizes at least one sound source for transmitting a signal (e.g., a sound wave or sound pulse through or across the battery, and at least one sound receiver for receiving a signal from the battery, which received signal is representative of the physical state of the battery being interrogated. The interrogation method is noninvasive, namely does not require the depletion of a portion of the charge of the battery being tested or settlement or the destruction of the battery in order to evaluate one or more of (i), (ii) and (iii). |
FILED | Friday, January 30, 2015 |
APPL NO | 14/610219 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/043 (20130101) G01N 29/46 (20130101) G01N 29/4427 (20130101) Original (OR) Class G01N 29/4436 (20130101) G01N 2291/0231 (20130101) G01N 2291/2698 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132853 | Liang et al. |
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APPLICANT(S) | Xiaodong Liang (St. John's, Canada); Scott Andrew Wallace (Portland, Oregon); Xinghui Zhao (Vancouver, Washington) |
ASSIGNEE(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
INVENTOR(S) | Xiaodong Liang (St. John's, Canada); Scott Andrew Wallace (Portland, Oregon); Xinghui Zhao (Vancouver, Washington) |
ABSTRACT | The embodiments herein are directed to monitoring in real time, power system data so as to provide insights into global operation of a power grid. Such a scheme disclosed herein utilizes rules, which are created by analyzing PMU measurement data, in order to detect the fault location (bus and line) and fault type. Three common types of faults in a power grid, single-line-to-ground (SLG), line-to-line (LL), and three phase faults, can be detected using the methods herein. |
FILED | Monday, April 11, 2016 |
APPL NO | 15/095266 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/025 (20130101) G01R 31/086 (20130101) Original (OR) Class Emergency Protective Circuit Arrangements H02H 1/0092 (20130101) H02H 7/26 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/728 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/265 (20130101) Y04S 10/522 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132942 | Frisch et al. |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois); Brookhaven Science Associates, LLC (Upton, New York) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Brookhaven Science Associates, LLC (Upton, New York) |
INVENTOR(S) | Henry J. Frisch (Chicago, Illinois); Eric J. Oberla (Chicago, Illinois); Hee-Jong Kim (Naperville, Illinois); Minfang Yeh (Stony Brook, New York) |
ABSTRACT | TOF-PET detector systems, and methods for imaging photon-emitting samples using the detector systems, are provided. The TOF-PET detector systems use large-area photodetectors with extremely high time-resolution and an approach to data collection and analysis that allows for the use of inexpensive low-density scintillator materials. The TOF-PET detector systems are characterized by their ability to identify, on a statistical basis, the transverse and depth location of the first of the series of energy deposition events that are generated when a gamma photon enters the low-density scintillator material. |
FILED | Friday, April 08, 2016 |
APPL NO | 15/553275 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) Measurement of Nuclear or X-radiation G01T 1/204 (20130101) G01T 1/2018 (20130101) G01T 1/2985 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133672 | Aguilera Diez et al. |
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APPLICANT(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
ASSIGNEE(S) | Advanced Micro Devices, Inc. (Sunnyvale, California) |
INVENTOR(S) | Paula Aguilera Diez (San Jose, California); Amin Farmahini-Farahani (Sunnyvale, California); Nuwan Jayasena (Sunnyvale, California) |
ABSTRACT | Described is a system and method for efficient pointer chasing in systems having a single memory node or a network of memory nodes. In particular, a pointer chasing command is sent along with a memory request by an issuing node to a memory node. The pointer chasing command indicates the number of interdependent memory accesses and information needed for the identified interdependent memory accesses. An address computing unit associated with the memory node determines the relevant memory address for an interdependent memory access absent further interaction with the issuing node or without having to return to the issuing node. |
FILED | Thursday, September 15, 2016 |
APPL NO | 15/267097 |
ART UNIT | 2135 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 12/0804 (20130101) G06F 12/0864 (20130101) Original (OR) Class G06F 2212/608 (20130101) G06F 2212/1008 (20130101) G06F 2212/1021 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134491 | Perkins et al. |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livewrmore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Lindsay John Perkins (Pleasanton, California); Jim H. Hammer (Livermore, California); John D. Moody (Livermore, California); Max Tabak (Livermore, California); George Beedon Zimmerman (Lafayette, California); Burl Grant Logan (Danville, California) |
ABSTRACT | Application of axial seed magnetic fields in the range 20-100 T that compress to greater than 10,000 T (100 MG) under typical NIF implosion conditions may significantly relax the conditions required for ignition and propagating burn in NIF ignition targets that are degraded by hydrodynamic instabilities. Such magnetic fields can: (a) permit the recovery of ignition, or at least significant alpha particle heating, in submarginal NIF targets that would otherwise fail because of adverse hydrodynamic instability growth, (b) permit the attainment of ignition in conventional cryogenic layered solid-DT targets redesigned to operate under reduced drive conditions, (c) permit the attainment of volumetric ignition in simpler, room-temperature single-shell DT gas capsules, and (d) ameliorate adverse hohlraum plasma conditions during laser drive and capsule compression. In general, an applied magnetic field should always improve the ignition condition for any NIF ignition target design. |
FILED | Thursday, May 15, 2014 |
APPL NO | 14/278611 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Fusion Reactors G21B 1/03 (20130101) G21B 1/05 (20130101) G21B 1/19 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/14 (20130101) Y02E 30/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134497 | Ehst et al. |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | David A. Ehst (Downers Grove, Illinois); James L. Willit (Batavia, Illinois) |
ABSTRACT | The present invention provides a method for producing Cu67 radioisotope suitable for use in medical applications. The method comprises irradiating a metallic zinc-68 (Zn68) target within a sealed ceramic capsule with a high energy gamma ray beam. After irradiation, the Cu67 is isolated from the Zn68 by any suitable method (e.g. chemical and or physical separation). In a preferred embodiment, the Cu67 is isolated by sublimation of the zinc in a ceramic sublimation tube to afford a copper residue containing Cu67. The Cu67 can be further purified by chemical means. |
FILED | Thursday, March 31, 2016 |
APPL NO | 15/087111 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Separation B01D 7/00 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) Original (OR) Class G21G 1/12 (20130101) G21G 2001/0094 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134572 | Laskin et al. |
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APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Julia Laskin (Richland, Washington); Son N. Nguyen (Richland, Washington); Andrey V. Liyu (Pasco, Washington) |
ABSTRACT | A system includes a mass spectrometer and associated sample interfacing equipment. The sample interfacing equipment includes a platform structured to support a sample thereon, a fluid source, a high voltage source, a dispensing probe electrically coupled to the high voltage source and defining a fluid dispensing passage therethrough, a collection probe defining a collection passage therethrough, a sensing arrangement coupled to the dispensing probe, and control logic responsive to the sensing arrangement to control distance between the dispensing probe and the sample. The dispensing probe facilitates formation of one or more ionized sample analytes when dispensing the fluid through the dispensing passage proximate to the sample on the platform. The collecting probe receives at least some of the one or more ionized sample analytes to pass through the collection passage into the mass spectrometer for analysis. |
FILED | Monday, August 01, 2016 |
APPL NO | 15/225585 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) H01J 49/0027 (20130101) Original (OR) Class H01J 49/0409 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134590 | Burst et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | James M. Burst (Lakewood, Colorado); David S. Albin (Denver, Colorado); Eric Colegrove (Denver, Colorado); Matthew O. Reese (Golden, Colorado); Helio R. Moutinho (Littleton, Colorado); Wyatt K. Metzger (Louisville, Colorado); Joel N. Duenow (Golden, Colorado) |
ABSTRACT | Systems and methods for growing high-quality CdTe-based materials at high growth rates are provided. According to an aspect of the invention, a method includes depositing a first CdTe-based layer on a CdTe-based template at a rate of greater than 1 μm/min. Each of the first CdTe-based layer and the CdTe-based template has a single-crystal structure and/or a large-grain polycrystalline structure. The depositing is performed by physical vapor deposition. |
FILED | Monday, March 27, 2017 |
APPL NO | 15/470195 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/24 (20130101) C23C 14/0629 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 11/14 (20130101) C30B 13/32 (20130101) C30B 23/025 (20130101) C30B 23/066 (20130101) C30B 29/48 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0248 (20130101) H01L 21/02381 (20130101) H01L 21/02562 (20130101) Original (OR) Class H01L 21/02631 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134851 | Chu et al. |
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FUNDED BY |
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APPLICANT(S) | HRL LABORATORIES, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Rongming Chu (Agoura Hills, California); Yu Cao (Agoura Hills, California); Zijian “Ray” Li (Thousand Oaks, California); Adam J. Williams (Malibu, California) |
ABSTRACT | A diode includes: a semiconductor substrate; a cathode metal layer contacting a bottom of the substrate; a semiconductor drift layer on the substrate; a graded aluminum gallium nitride (AlGaN) semiconductor barrier layer on the drift layer and having a larger bandgap than the drift layer, the barrier layer having a top surface and a bottom surface between the drift layer and the top surface, the barrier layer having an increasing aluminum composition from the bottom surface to the top surface; and an anode metal layer directly contacting the top surface of the barrier layer. |
FILED | Thursday, December 14, 2017 |
APPL NO | 15/842002 |
ART UNIT | 2898 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) Original (OR) Class H01L 29/0619 (20130101) H01L 29/872 (20130101) H01L 29/2003 (20130101) H01L 29/66212 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134927 | Voss et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Lars Voss (Livermore, California); Mihail Bora (Livermore, California); George Caporaso (Livermore, California); Adam Conway (Livermore, California); Hoang T. Nguyen (Livermore, California); Rebecca J. Nikolic (Oakland, California); Stephen E. Sampayan (Manteca, California); Sangtae Park (San Ramon, California) |
ABSTRACT | A photoconductive switch consisting of an optically actuated photoconductive material, e.g. a wide bandgap semiconductor such as SiC, situated between opposing electrodes. The electrodes are created using various methods in order to maximize reliability by reducing resistive heating, current concentrations and filamentation, and heating and ablation due to the light source. This is primarily accomplished by the configuration of the electrical contact geometry, choice of contacts metals, annealing, ion implantation, creation of recesses within the SiC, and the use of coatings to act as encapsulants and anti-reflective layers. |
FILED | Friday, July 08, 2016 |
APPL NO | 15/206133 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4295 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) H01L 31/0312 (20130101) H01L 31/02327 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134929 | Gershon et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Talia S. Gershon (White Plains, New York); Richard A. Haight (Mahopac, New York); Marinus Hopstaken (Carmel, New York); Yun Seog Lee (White Plains, New York) |
ABSTRACT | Techniques for achieving band gap grading in CZTS/Se absorber materials are provided. In one aspect, a method for creating band gap grading in a CZTS/Se absorber layer includes the steps of: providing a reservoir material containing Si or Ge; forming the CZTS/Se absorber layer on the reservoir material; and annealing the reservoir material and the CZTS/Se absorber layer under conditions sufficient to diffuse Si or Ge atoms from the reservoir material into the CZTS/Se absorber layer with a concentration gradient to create band gap grading in the CZTS/Se absorber layer. A photovoltaic device and method of forming the photovoltaic device are also provided. |
FILED | Wednesday, October 14, 2015 |
APPL NO | 14/883300 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0245 (20130101) H01L 21/0251 (20130101) H01L 21/0256 (20130101) H01L 21/02381 (20130101) H01L 21/02474 (20130101) H01L 21/02477 (20130101) H01L 21/02485 (20130101) H01L 21/02557 (20130101) H01L 21/02568 (20130101) H01L 21/02573 (20130101) H01L 21/02664 (20130101) H01L 31/065 (20130101) H01L 31/072 (20130101) H01L 31/0326 (20130101) Original (OR) Class H01L 31/0392 (20130101) H01L 31/1864 (20130101) H01L 31/1892 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135386 | Goldberg et al. |
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FUNDED BY |
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APPLICANT(S) | Smash Solar, Inc. (Richmond, California) |
ASSIGNEE(S) | Smash Solar, Inc. (Richmond, California) |
INVENTOR(S) | Neil Goldberg (Berkeley, California); Troy Douglas Tyler (El Cerrito, California); David Mathew Johnson (San Francisco, California) |
ABSTRACT | A solar module system is coupled directly to a fixed structure either individually or collectively as an array. Universal mounting brackets attached to the back of each solar panel module each connect to one or more other brackets of adjacent solar panels and/or to mounting feet that anchor to the fixed structure. Mounting brackets interlock with mounting brackets on adjacent solar modules and include a flexible snap coupling mechanism including a locking feature to selectively flexibly connect to and disconnect from other mounting brackets of adjacent solar panels. |
FILED | Wednesday, October 22, 2014 |
APPL NO | 14/521245 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Producing or Use of Heat Not Otherwise Provided For F24J 2/4607 (20130101) F24J 2/5237 (20130101) F24J 2/5239 (20130101) F24J 2/5245 (20130101) F24J 2/5254 (20130101) F24J 2/5262 (20130101) F24J 2002/4661 (20130101) F24J 2002/4669 (20130101) F24J 2002/5281 (20130101) F24J 2002/5486 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/05 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/00 (20130101) H02S 20/23 (20141201) Original (OR) Class H02S 20/24 (20141201) H02S 40/32 (20141201) H02S 40/36 (20141201) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 10/12 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/47 (20130101) Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135388 | Madrone et al. |
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APPLICANT(S) | SUNFOLDING, INC. (San Francisco, California) |
ASSIGNEE(S) | SUNFOLDING, INC. (San Francisco, None) |
INVENTOR(S) | Leila Marcia Madrone (San Francisco, California); Kyle Douglas Betts (San Francisco, California); Peter Sturt Lynn (Oakland, California); Louis Hong Basel (Berkeley, California); Brent Ridley (Huntington Beach, California); Saul Thomas Griffith (San Francisco, California); James Dylan McBride (San Francisco, California); Jeffrey Lamb (San Francisco, California); Eric Preston Lien Suan (Baltimore, Maryland); Erica Lin (Millbrae, California); Joshua Erickson (Oakland, California); Vincent Domenic Romanin (San Francisco, California) |
ABSTRACT | A pneumatically actuated solar panel array system that includes a plurality of separate actuator assemblies that each have a top plate and bottom plate and a first and second bellows that each extend between and are coupled to the top and bottom plates at a respective top head and bottom head, the first and second bellows being configured to be separately pneumatically inflated, where the pneumatic inflation expands the bellows along a length. The pneumatically actuated solar panel array system can also include a plurality of solar panels coupled to the actuator assemblies with the solar panels being configured to be actuated based on inflation of one or more bellows associated with the plurality of actuator assembles. |
FILED | Monday, February 01, 2016 |
APPL NO | 15/012715 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/10 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/30 (20141201) H02S 20/32 (20141201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135924 | Bent et al. |
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APPLICANT(S) | EMC IP Holding Company LLC (Hopkinton, Massachusetts) |
ASSIGNEE(S) | EMC IP Holding Company LLC (Hopkinton, Massachusetts); Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | John M. Bent (Los Alamos, New Mexico); Sorin Faibish (Newton, Massachusetts); Dennis P. J. Ting (Groton, Massachusetts); Sasan Teymouri (Saratoga, California); James M. Pedone, Jr. (West Boylston, Massachusetts); Gary Grider (Los Alamos, New Mexico) |
ABSTRACT | Techniques are provided for computing data and metadata layout prior to storage in a storage system using a processing platform. An exemplary processing platform comprises one or more of a compute node and a burst buffer appliance. The processing platform communicates with a plurality of the compute nodes over a network, wherein a plurality of applications executing on the plurality of compute nodes generate a plurality of data objects; computes erasure metadata for one or more of the data objects on at least one of the compute nodes; and provides the erasure metadata with the corresponding one or more data objects to a storage system. The processing platform optionally determines a full set of the data objects to be stored and queries the storage system to determine an anticipated layout of the full set of the data objects to be stored. The anticipated layout allows special handling, for example, for small files and large files that are identified based on predefined criteria. |
FILED | Friday, June 26, 2015 |
APPL NO | 14/751372 |
ART UNIT | 2137 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 3/0611 (20130101) G06F 3/0689 (20130101) G06F 15/167 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1097 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10136529 | McPherson et al. |
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FUNDED BY |
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APPLICANT(S) | Cree Fayetteville, Inc. (Fayetteville, Arkansas) |
ASSIGNEE(S) | Cree Fayetteville, Inc. (Fayetteville, Arkansas) |
INVENTOR(S) | Brice McPherson (Fayetteville, Arkansas); Peter Killeen (Fayetteville, Arkansas); Alex Lostetter (Fayetteville, Arkansas); Robert Shaw (Fayetteville, Arkansas); Brandon Passmore (Fayetteville, Arkansas); Jared Hornberger (Fayetteville, Arkansas); Tony M. Berry (Springdale, Arkansas) |
ABSTRACT | A method of making a power module includes providing a base plate defining a topology pattern, providing a power substrate above the base plate, providing at least two power contacts and arranging solder catches in the at least two power contacts, soldering the at least two power contacts to the power substrate utilizing the solder catches, and securing a housing to the power substrate. |
FILED | Monday, August 15, 2016 |
APPL NO | 15/236844 |
ART UNIT | 2847 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4817 (20130101) H01L 23/15 (20130101) H01L 23/049 (20130101) H01L 23/3675 (20130101) H01L 23/3735 (20130101) H01L 23/49838 (20130101) H01L 23/49861 (20130101) H01L 25/07 (20130101) H01L 25/072 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0296 (20130101) H05K 5/0013 (20130101) H05K 5/0069 (20130101) Original (OR) Class H05K 5/0091 (20130101) H05K 5/0247 (20130101) H05K 7/20509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10136556 | Bilski et al. |
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FUNDED BY |
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APPLICANT(S) | Thermal Corp. (Wilmington, Delaware) |
ASSIGNEE(S) | Thermal Corp. (Wilmington, Delaware) |
INVENTOR(S) | Walter John Bilski (Mohnton, Pennsylvania); Sidrit Kosta (Philadelphia, Pennsylvania) |
ABSTRACT | An electronics rack comprising a frame, a heat sink coupled to the frame, and a cage adapted to support an electronic component. The cage is movable between first and second positions toward and away from the heat sink. The rack further includes an eccentric cam operatively positioned between the frame and the cage and being rotatable to move the cage between the first and second positions. In one embodiment, the cage comprises a cooling brick movable toward and away from the heat sink when the cage moves between the first and second positions. The cooling brick can include a first heat pipe extending generally in a first direction and a second heat pipe extending generally in a second direction transverse to the first direction. For example, the first heat pipe can be embedded in a top plate and the second heat pipe can be embedded in a top cold rail. |
FILED | Friday, February 24, 2017 |
APPL NO | 15/441792 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/1487 (20130101) H05K 7/20445 (20130101) H05K 7/20545 (20130101) Original (OR) Class H05K 7/20672 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 10130716 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Andrew Keefe (Seattle, Washington); Hong Xue (Pleasanton, California) |
ABSTRACT | Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates. |
FILED | Wednesday, October 29, 2014 |
APPL NO | 14/526846 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4826 (20130101) A61K 47/48176 (20130101) Original (OR) Class Enzymes C12Y 304/21001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131127 | Mutzel et al. |
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FUNDED BY |
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APPLICANT(S) | Tufts University (Medford, Massachusetts) |
ASSIGNEE(S) | Tufts University (Medford, Massachusetts) |
INVENTOR(S) | Chris Mutzel (Seattle, Washington); Sameer Sonkusale (Arlington, Massachusetts) |
ABSTRACT | A method of making an electrically active structure includes applying a backplane onto a substrate, applying a paint layer onto said backplane, applying a stencil layer on said paint layer, patterning an electrically active structure onto said paint layer through said stencil layer, and removing said stencil layer. |
FILED | Friday, June 14, 2013 |
APPL NO | 14/408091 |
ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/14 (20130101) Original (OR) Class B32B 38/10 (20130101) B32B 38/145 (20130101) B32B 2307/204 (20130101) B32B 2307/208 (20130101) B32B 2457/00 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/06 (20130101) Antennas, i.e Radio Aerials H01Q 15/0086 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/024 (20130101) H05K 1/0236 (20130101) H05K 3/1225 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24628 (20150115) Y10T 428/24802 (20150115) Y10T 428/31855 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131133 | Bentz et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
INVENTOR(S) | Brian Zahler Bentz (Albuquerque, New Mexico); Kevin J Webb (West Lafayette, Indiana) |
ABSTRACT | An optically heterogeneous phantom structure for use in optical imaging techniques. The phantom structure includes an external shape simulating an object to be subjected to an optical imaging technique, the external shape defining an external surface that encloses an internal volume of the external shape; and an optically heterogeneous material filling the internal volume and having heterogeneous optical properties for simulating at least one optical parameter of at least one region within the object. A method of producing the optically heterogeneous phantom structure. The method includes selectively depositing precursors of a first material and a second material by 3D printing so that the precursor of the second material is surrounded by the precursor of the first material within a predetermined internal region of the precursor of the first material, and forming the phantom structure. Variations of the method include additives to the materials. |
FILED | Thursday, October 12, 2017 |
APPL NO | 15/782179 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/583 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/40 (20170801) B29C 64/129 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0026 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/40 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Original (OR) Class Image Data Processing or Generation, in General G06T 11/003 (20130101) Pictorial Communication, e.g Television H04N 5/372 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131585 | Newman et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Dianne K. Newman (Pasadena, California); Gargi Kulkarni (Pasadena, California); Brittany Jo Belin (Pasadena, California); Eric Geraud (Marseilles, France); Antonio Molinaro (Napoli, Italy); Alba Silipo (Napoli, Italy) |
ABSTRACT | Hopanoids, hopanoids-producing nitrogen-fixing bacteria, and related formulations, systems and methods are described herein. In particular, hopanoids alone or in combination with hopanoid-producing nitrogen-fixing bacteria can be used as biofertilizer to stimulate plant growth and yield with enhanced tolerance to diverse stresses found in plant-microbe symbiotic microenvironments. |
FILED | Wednesday, October 19, 2016 |
APPL NO | 15/298172 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/20 (20130101) C12N 15/52 (20130101) C12N 15/82 (20130101) Enzymes C12Y 402/01084 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131755 | Singh |
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FUNDED BY |
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APPLICANT(S) | New Jersey Institute of Technology (Newark, New Jersey) |
ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
INVENTOR(S) | Pushpendra Singh (Pine Brook, New Jersey) |
ABSTRACT | The present invention relates to a method for the formation of virtually defect-free monolayers of particles with long-range order. The technique involves assembling the monolayer of particles on the interface between a solidifiable liquid and a fluid, which can be air or another liquid, ordering the particles using an electric field and then solidifying the former, e.g., by applying UV light. The monolayer becomes embedded on the surface of the solidified film. The monolayers can be coated onto the surface of materials to optimize their mechanical, thermal, electrical and optical properties. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/212761 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/62 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/06 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/268 (20150115) Y10T 428/249921 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131996 | Kemp et al. |
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FUNDED BY |
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APPLICANT(S) | Richard Kemp (Albuquerque, New Mexico); Diane A. Dickie (Albuquerque, New Mexico); Elizabeth S. Donovan (Albuquerque, New Mexico); Brian Barry (Dubuque, Iowa) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Richard Kemp (Albuquerque, New Mexico); Diane A. Dickie (Albuquerque, New Mexico); Elizabeth S. Donovan (Albuquerque, New Mexico); Brian Barry (Dubuque, Iowa) |
ABSTRACT | Novel complexes of various earth-abundant, inexpensive transition or main group metals that facilitate the transformation of carbon dioxide into other more useful organic products. These complexes can bind and alter the CO2 at mild conditions of temperature and pressure, enabling, according to some embodiments, the electrochemical conversion of CO2 into new products. |
FILED | Tuesday, March 03, 2015 |
APPL NO | 15/123900 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/189 (20130101) B01J 31/1815 (20130101) B01J 2231/625 (20130101) B01J 2531/26 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 3/04 (20130101) Original (OR) Class C25B 11/0405 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132238 | Sun et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Zongxuan Sun (Plymouth, Minnesota); Ke Li (Minneapolis, Minnesota); Ali Sadighi (Redondo Beach, California) |
ABSTRACT | Motion control of a hydraulic free-piston engine is achieved in order to enable advanced combustions such as low temperature combustion. To accomplish this, an active controller acts as a virtual crankshaft, which causes a piston to follow a reference trajectory using energy from a storage element. Given the periodic nature of free-piston engine motion, an advanced controller of the present invention is preferably of robust repetitive type that is capable of tracking periodic reference signals. |
FILED | Tuesday, April 02, 2013 |
APPL NO | 13/855363 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 63/06 (20130101) F02B 71/00 (20130101) Original (OR) Class F02B 71/04 (20130101) F02B 71/045 (20130101) Controlling Combustion Engines F02D 35/02 (20130101) F02D 35/023 (20130101) F02D 35/025 (20130101) F02D 41/1497 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132609 | Popescu et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Gabriel Popescu (Champaign, Illinois); Mikhail Eugene Kandel (Champaign, Illinois); Tan Huu Nguyen (Quincy, Massachusetts) |
ABSTRACT | A system and methods for quantitative optical phase imaging of a sample. First second replica field of an image field are generated, characterized by a respective optical phase, cross-polarized and shifted in a shift direction transverse to a normal to the surface of the sample. The replica fields are Fourier transformed, the second replica field is retarded by four successive phase shifts, and, after inverse Fourier transforming, the first and second replica fields pass through an analyzer polarizer and superposing the first and second replica fields on a detector array to create four successive detector signals. The four successive detector signals are solved to derive a gradient of the optical phase of the image field, which may be integrated to obtain a quantitative phase image. |
FILED | Wednesday, November 15, 2017 |
APPL NO | 15/813951 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/04 (20130101) G01B 9/02041 (20130101) Original (OR) Class G01B 11/24 (20130101) G01B 11/2441 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132781 | Steingart et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Daniel Artemus Steingart (Princeton, New Jersey); Shoham Bhadra (North Brunswick, New Jersey); Andrew Hsieh (Princeton, New Jersey); Benjamin Hertzberg (Princeton, New Jersey); Peter James Gjeltema (Stow, Massachusetts); Clarence Worth Rowley, III (Princeton, New Jersey); Alexandre S. R. Goy (Lawrenceville, New Jersey); Jason Wolf Fleischer (Princeton, New Jersey) |
ABSTRACT | A method, an apparatus and a system for interrogating a battery in order to determine one or more of: (i) its state of charge (SOC), (ii) its state of health (SOH), (iii) physical state of one or more internal components or parts, which utilizes at least one sound source for transmitting a signal (e.g., a sound wave or sound pulse through or across the battery, and at least one sound receiver for receiving a signal from the battery, which received signal is representative of the physical state of the battery being interrogated. The interrogation method is noninvasive, namely does not require the depletion of a portion of the charge of the battery being tested or settlement or the destruction of the battery in order to evaluate one or more of (i), (ii) and (iii). |
FILED | Friday, January 30, 2015 |
APPL NO | 14/610219 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/043 (20130101) G01N 29/46 (20130101) G01N 29/4427 (20130101) Original (OR) Class G01N 29/4436 (20130101) G01N 2291/0231 (20130101) G01N 2291/2698 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132942 | Frisch et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois); Brookhaven Science Associates, LLC (Upton, New York) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Brookhaven Science Associates, LLC (Upton, New York) |
INVENTOR(S) | Henry J. Frisch (Chicago, Illinois); Eric J. Oberla (Chicago, Illinois); Hee-Jong Kim (Naperville, Illinois); Minfang Yeh (Stony Brook, New York) |
ABSTRACT | TOF-PET detector systems, and methods for imaging photon-emitting samples using the detector systems, are provided. The TOF-PET detector systems use large-area photodetectors with extremely high time-resolution and an approach to data collection and analysis that allows for the use of inexpensive low-density scintillator materials. The TOF-PET detector systems are characterized by their ability to identify, on a statistical basis, the transverse and depth location of the first of the series of energy deposition events that are generated when a gamma photon enters the low-density scintillator material. |
FILED | Friday, April 08, 2016 |
APPL NO | 15/553275 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) Measurement of Nuclear or X-radiation G01T 1/204 (20130101) G01T 1/2018 (20130101) G01T 1/2985 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133097 | Reano et al. |
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FUNDED BY |
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APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
INVENTOR(S) | Ronald M. Reano (Columbus, Ohio); Peng Sun (Carlsbad, California); Qiang Xu (Columbus, Ohio) |
ABSTRACT | An example optical polarization controller can include a substantially planar substrate and a waveguide unit cell formed on the substantially planar substrate. The waveguide unit cell can include a first out-of-plane waveguide portion and a second out-of-plane waveguide portion coupled to the first out-of-plane waveguide portion. Each of the first and second out-of-plane waveguide portions can respectively include a core material layer arranged between a first optical cladding layer having a first stress-response property and a second optical cladding layer having a second stress-response property. The first and second stress-response properties can be different such that each of the first and second out-of-plane waveguide portions is deflected by a deflection angle. |
FILED | Thursday, September 28, 2017 |
APPL NO | 15/718350 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/126 (20130101) G02B 6/136 (20130101) G02B 6/2934 (20130101) G02B 6/3504 (20130101) G02B 6/3596 (20130101) G02B 6/12002 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0136 (20130101) Original (OR) Class G02F 1/0147 (20130101) G02F 2201/06 (20130101) G02F 2202/10 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133323 | Hanumaiah et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents for and on behalf of Arizona State University (Scottsdale, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Vinay Hanumaiah (Campbell, California); Sarma Vrudhula (Chandler, Arizona); Benjamin Gaudette (Phoenix, Arizona) |
ABSTRACT | A control system for use with a processor includes: (i) a controller configured to receive prediction information for a predicted temperature associated with the processor, and to determine a speed of operation for the processor based at least on a thermal model of the processor and the predicted temperature, where the speed supports an operational objective of the processor; and (ii) an error estimator that is separate from the controller, and that is configured to receive temperature information obtained from the processor operating at the speed, to determine updated prediction information based, at least in part, on the temperature information, and to output the updated prediction information to the controller. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/207936 |
ART UNIT | 2126 — AI & Simulation/Modeling |
CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 23/19 (20130101) Electric Digital Data Processing G06F 1/206 (20130101) Original (OR) Class G06F 1/324 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/16 (20180101) Y02D 10/126 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133936 | Hu et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama) |
ASSIGNEE(S) | The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama) |
INVENTOR(S) | Fei Hu (Tuscaloosa, Alabama); Rui Ma (Tuscaloosa, Alabama); Qi Hao (Guangdong, China PRC) |
ABSTRACT | Disclosed and described herein is a system and a method for thermal detection of static and moving objects. |
FILED | Tuesday, June 13, 2017 |
APPL NO | 15/621404 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0025 (20130101) G01J 2005/0077 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00369 (20130101) G06K 9/00671 (20130101) G06K 9/00691 (20130101) G06K 9/00771 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134125 | Mauldin, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | Rivanna Medical LLC (Charlottesville, Virginia) |
ASSIGNEE(S) | Rivanna Medical LLC (Charlottesville, Virginia) |
INVENTOR(S) | Frank William Mauldin, Jr. (Charlottesville, Virginia); Kevin Owen (Crozet, Virginia) |
ABSTRACT | Techniques for processing ultrasound data. The techniques include using at least one computer hardware processor to perform obtaining ultrasound data generated based, at least in part, on one or more ultrasound signals from an imaged region of a subject; calculating shadow intensity data corresponding to the ultrasound data; generating, based at least in part on the shadow intensity data and at least one bone separation parameter, an indication of bone presence in the imaged region, generating, based at least in part on the shadow intensity data and at least one tissue separation parameter different from the at least one bone separation parameter, an indication of tissue presence in the imaged region; and generating an ultrasound image of the subject at least in part by combining the indication of bone presence and the indication of tissue presence. |
FILED | Wednesday, February 26, 2014 |
APPL NO | 14/770893 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/461 (20130101) A61B 8/0858 (20130101) A61B 8/0875 (20130101) A61B 8/5223 (20130101) A61B 8/5246 (20130101) A61B 8/5269 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/52 (20130101) G06K 9/4661 (20130101) G06K 2009/4666 (20130101) Image Data Processing or Generation, in General G06T 5/009 (20130101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/30 (20170101) G06T 11/60 (20130101) G06T 15/08 (20130101) G06T 2200/04 (20130101) G06T 2207/10132 (20130101) G06T 2207/30008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134599 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Xiuling Li (Champaign, Illinois); Jeong Dong Kim (Savoy, Illinois); Munho Kim (Champaign, Illinois); Lingyu Kong (Urbana, Illinois) |
ABSTRACT | A method of metal-assisted chemical etching comprises forming an array of discrete metal features on a surface of a semiconductor structure, where each discrete metal feature comprises a porous metal body with a plurality of pores extending therethrough and terminating at the surface of the semiconductor structure. The semiconductor structure is exposed to an etchant, and the discrete metal features sink into the semiconductor structure as metal-covered surface regions are etched. Simultaneously, uncovered surface regions are extruded through the pores to form anchoring structures for the discrete metal features. The anchoring structures inhibit detouring or delamination of the discrete metal features during etching. During continued exposure to the etchant, the anchoring structures are gradually removed, leaving an array of holes in the semiconductor structure. |
FILED | Friday, February 24, 2017 |
APPL NO | 15/441745 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/042 (20130101) H01L 21/0337 (20130101) H01L 21/0475 (20130101) H01L 21/2855 (20130101) H01L 21/3086 (20130101) H01L 21/28568 (20130101) H01L 21/30604 (20130101) Original (OR) Class H01L 21/30612 (20130101) H01L 21/32133 (20130101) H01L 21/32139 (20130101) H01L 21/76898 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134634 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
INVENTOR(S) | Liyi Li (Atlanta, Georgia); Ching Ping Wong (Berkeley Lake, Georgia); Jack K. Moon (Duluth, Georgia); Xueying Zhao (Atlanta, Georgia) |
ABSTRACT | An embodiment of a method for metal-assisted chemical etching of a semiconductive substrate comprises forming a patterned coating on a top surface of a substrate layer of a silicon wafer; applying a noble metal layer over the patterned coating such that a portion of the noble metal layer is in contact with the top surface of the substrate layer; and immersing the silicon wafer in a wet etching solution to form a trench under the portion of the noble metal layer that is contact with the top surface of the substrate layer. Further, the trench may be filled with copper material to form a through silicon via structure. Such embodiments provide etching techniques that enable etched formations that are deep (e.g., high-aspect-ratio) and uniform as opposed to shallow etchings (i.e., low-aspect-ratio) or non-uniform deep etchings. |
FILED | Monday, November 02, 2015 |
APPL NO | 14/930161 |
ART UNIT | 2897 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/78 (20130101) H01L 21/30604 (20130101) H01L 21/67086 (20130101) H01L 21/76898 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134985 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | Wei Lu (Ann Arbor, Michigan); Sung Hyun Jo (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Wei Lu (Ann Arbor, Michigan); Sung Hyun Jo (Ann Arbor, Michigan) |
ABSTRACT | Non-crystalline silicon non-volatile resistive switching devices include a metal electrode, a non-crystalline silicon layer and a planar doped silicon electrode. An electrical signal applied to the metal electrode drives metal ions from the metal electrode into the non-crystalline silicon layer to form a conducting filament from the metal electrode to the planar doped silicon electrode to alter a resistance of the non-crystalline silicon layer. Another electrical signal applied to the metal electrode removes at least some of the metal ions forming the conducting filament from the non-crystalline silicon layer to further alter the resistance of the non-crystalline silicon layer. |
FILED | Friday, October 19, 2007 |
APPL NO | 11/875541 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/2472 (20130101) H01L 27/2481 (20130101) H01L 45/14 (20130101) Original (OR) Class H01L 45/085 (20130101) H01L 45/148 (20130101) H01L 45/1233 (20130101) H01L 45/1266 (20130101) H01L 45/1616 (20130101) H01L 45/1675 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134989 | Smith et al. |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Alexander James Smith (Chicago, Illinois); Chen Wang (Evanston, Illinois); Jiaxing Huang (Wilmette, Illinois); Cheng Sun (Wilmette, Illinois) |
ABSTRACT | Photonic devices are provided comprising a photoactive layer and at least one additional layer, wherein a surface of the photoactive layer or a surface of the at least one additional layer has imprinted thereon a quasi-random pattern of nanostructures corresponding to a quasi-random pattern of nanostructures defined in a recording layer of a pre-written optical media disc. Methods of patterning a layer of a photonic device are also provided. |
FILED | Wednesday, September 06, 2017 |
APPL NO | 15/696769 |
ART UNIT | 2829 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0014 (20130101) Original (OR) Class H01L 51/44 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135506 | Hafez et al. |
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APPLICANT(S) | Mohammed Hafez (Tampa, Florida); Huseyin Arslan (Tampa, Florida); Tamer Khattab (Doha, Qatar) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Mohammed Hafez (Tampa, Florida); Huseyin Arslan (Tampa, Florida); Tamer Khattab (Doha, Qatar) |
ABSTRACT | Method and system for transmitting a directionally modulated data stream via an antenna array. A first signal processing circuitry receives a data symbol of a first data stream, maps the first data stream to a specified number of sub-beams based on a stream beam-width assignment, assigns a direction angle for transmission of the data stream, and transmits in parallel, for each of the specified number of sub-beams, an instance of the data symbol to a second signal processing circuitry. The second signal processing circuitry generates antenna array element weights based on the data symbol and a matrix having a DFT structure. The matrix is independent of the assigned direction angle. The data symbol is transmitted via the antenna array utilizing the antenna array element weights. The DFT is implemented as a fast Fourier transform. White noise is transmitted in the sub-beams beams outside the beam-width requirement of the data stream. |
FILED | Thursday, November 30, 2017 |
APPL NO | 15/827813 |
ART UNIT | 2632 — Digital Communications |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/26 (20130101) H01Q 3/28 (20130101) H01Q 3/40 (20130101) H01Q 21/245 (20130101) H01Q 25/00 (20130101) Transmission H04B 7/0456 (20130101) Original (OR) Class H04B 7/0617 (20130101) H04B 7/0697 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135539 | Moss et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Benjamin Roy Moss (Brookline, Massachusetts); Jason Scott Orcutt (Somerville, Massachusetts); Vladimir Marko Stojanovic (Lexington, Massachusetts) |
ABSTRACT | Devices and techniques for integrated optical data communication. A method of encoding symbols in an optical signal may include encoding a first symbol by injecting charge carriers, at a first rate, into a semiconductor device, such as a PIN diode. The method may also include encoding a second symbol by injecting charge carriers, at a second rate, into the semiconductor device. The first rate may exceed the second rate. A modulator driver circuit may include a resistive circuit coupled between supply terminal and drive terminals. The modulator driver circuit may also include a control circuit coupled between a data terminal and the resistive circuit. The control circuit may modulate a resistance of the resistive circuit by selectively coupling one or more of a plurality of portions of the resistive circuit to the drive terminal based on data to be optically encoded. In some embodiments, a modulator driver circuit and an optical modulator may be integrated on the same die or stacked (3D integrated) die and connected with through-oxide or through-silicon vias. |
FILED | Friday, February 15, 2013 |
APPL NO | 14/436613 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0121 (20130101) G02F 1/0123 (20130101) G02F 2203/15 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/823437 (20130101) H01L 31/18 (20130101) H01L 31/105 (20130101) Transmission H04B 10/516 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135849 | Jha et al. |
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APPLICANT(S) | Niraj K. Jha (Westfield, New Jersey); Anand Raghunathan (West Lafayette, Indiana); Meng Zhang (Princeton, New Jersey) |
ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | Niraj K. Jha (Westfield, New Jersey); Anand Raghunathan (West Lafayette, Indiana); Meng Zhang (Princeton, New Jersey) |
ABSTRACT | A medical device monitor (MedMon), method and computer readable medium is disclosed. The MedMon is configured to operate in a system having communications between a first medical device associated with a patient and a second device. The MedMon includes a receiver configured to snoop on communications between the first medical device and second device. An anomaly detector having a set of security polices is configured to detect an anomaly by analyzing the communications between the first medical device and second device for compliance with the security policies. A response generator configured to generate a response on a condition that an anomaly is detected. The response may be a warning message configured to warn the patient. The MedMon may include a transmitter configured to transmit the response. The response may be a jamming signal configured to disrupt communications between the first medical device and second device. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/839768 |
ART UNIT | 2491 — Cryptography and Security |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/14532 (20130101) Electric Digital Data Processing G06F 19/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 10131183 | Nesnas et al. |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); JAPAN AEROSPACE EXPLORATION AGENCY (Tokyo, Japan) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); JAPAN AEROSPACE EXPLORATION AGENCY (Tokyo, Japan) |
INVENTOR(S) | Issa A. Nesnas (San Marino, California); Masatsugu Otsuki (Kanagawa, Japan) |
ABSTRACT | A wheel includes a circular wheel main body and at least one grouser. The at least one grouser is provided along an outer circumference of the wheel main body and has a contact surface capable of drawing a first tangent line. The first tangent line is inclined opposite to a rotational direction of the wheel main body from the center line of the wheel main body. |
FILED | Thursday, November 10, 2016 |
APPL NO | 15/348913 |
ART UNIT | 3617 — Optics |
CURRENT CPC | Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 11/02 (20130101) B60B 15/18 (20130101) Original (OR) Class B60B 2900/551 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131585 | Newman et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Dianne K. Newman (Pasadena, California); Gargi Kulkarni (Pasadena, California); Brittany Jo Belin (Pasadena, California); Eric Geraud (Marseilles, France); Antonio Molinaro (Napoli, Italy); Alba Silipo (Napoli, Italy) |
ABSTRACT | Hopanoids, hopanoids-producing nitrogen-fixing bacteria, and related formulations, systems and methods are described herein. In particular, hopanoids alone or in combination with hopanoid-producing nitrogen-fixing bacteria can be used as biofertilizer to stimulate plant growth and yield with enhanced tolerance to diverse stresses found in plant-microbe symbiotic microenvironments. |
FILED | Wednesday, October 19, 2016 |
APPL NO | 15/298172 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/20 (20130101) C12N 15/52 (20130101) C12N 15/82 (20130101) Enzymes C12Y 402/01084 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10132527 | Yagoobi |
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FUNDED BY |
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APPLICANT(S) | WORCESTER POLYTECHNIC INSTITUTE (Worcester, Massachusetts) |
ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
INVENTOR(S) | Jamal S. Yagoobi (Hopkinton, Massachusetts) |
ABSTRACT | An electrohydrodynamic (EHD) pump increases refrigerant flow rate and the resulting pressure in a vapor compression based cooling system for permitting reduced compressor sizes and power demands. The EHD pump disposes electrodes in a liquid path of the refrigerant flow, and increases fluid flow and resulting pressure by an induced liquid flow between a pair of asymmetric electrodes. Voltage applied to these electrodes results in a conduction pumping mechanism associated with heterocharge layers in the vicinity of the electrodes based on disassociation of a neutral electrolyte species in the refrigerant fluid and recombination of the generated ions. The induced flow draws the liquid due to a net fluid flow toward one of the electrodes based on the asymmetry of the electrode pair. Electrodes are disposed on an inner surface of a refrigerant vessel, in communication with an annular liquid film that forms around the inner circumference in two-phase fluid systems. |
FILED | Thursday, September 29, 2016 |
APPL NO | 15/279852 |
ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Positive-displacement Machines for Liquids; Pumps F04B 19/006 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 1/00 (20130101) F25B 1/10 (20130101) Original (OR) Class F25B 31/00 (20130101) Dynamo-electric Machines H02K 44/02 (20130101) Electric Machines Not Otherwise Provided for H02N 11/006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 10131637 | Abdel-Meguid et al. |
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FUNDED BY |
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APPLICANT(S) | Shifa Biomedical Corporation (Malvern, Pennsylvania); Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Shifa Biomedical Corporation (Malvern, Pennsylvania); Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
INVENTOR(S) | Sherin Salaheldin Abdel-Meguid (Exton, Pennsylvania); Magid Abou-Gharbia (Exton, Pennsylvania); Benjamin Blass (Eagleville, Pennsylvania); Wayne Childers (New Hope, Pennsylvania); Nabil Elshourbagy (West Chester, Pennsylvania); Victor Ghidu (Philadelphia, Pennsylvania); Rogelio Martinez (Trenton, New Jersey); Harold Meyers (Weston, Massachusetts); Shaker A. Mousa (Wynantskill, New York) |
ABSTRACT | Disclosed are compounds of the class of 2-phenylacetamides that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia. |
FILED | Tuesday, March 11, 2014 |
APPL NO | 14/767126 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/18 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/42 (20130101) A61K 31/167 (20130101) A61K 31/235 (20130101) A61K 31/245 (20130101) A61K 31/397 (20130101) A61K 31/401 (20130101) A61K 31/415 (20130101) A61K 31/435 (20130101) A61K 31/437 (20130101) A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/4164 (20130101) A61K 31/4418 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 235/38 (20130101) C07C 237/42 (20130101) C07C 271/28 (20130101) C07C 275/40 (20130101) C07C 275/42 (20130101) C07C 311/47 (20130101) C07C 2601/02 (20170501) C07C 2601/08 (20170501) Heterocyclic Compounds C07D 211/14 (20130101) C07D 211/70 (20130101) C07D 211/96 (20130101) C07D 213/68 (20130101) C07D 213/74 (20130101) C07D 213/82 (20130101) C07D 231/12 (20130101) C07D 233/90 (20130101) C07D 239/42 (20130101) Original (OR) Class C07D 241/04 (20130101) C07D 241/08 (20130101) C07D 261/08 (20130101) C07D 295/14 (20130101) C07D 401/06 (20130101) C07D 403/12 (20130101) C07D 471/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10131901 | Abrams et al. |
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APPLICANT(S) | SAGE SCIENCE, INC. (Beverly, Massachusetts) |
ASSIGNEE(S) | SAGE SCIENCE, INC. (Beverly, Massachusetts) |
INVENTOR(S) | Ezra S. Abrams (Newton, Massachusetts); Danny Yun (S. Hamilton, Massachusetts); Todd J. Barbera (Marblehead, Massachusetts); Douglas Grosvenor Sabin (Marblehead, Massachusetts); T. Christian Boles (Bedford, Massachusetts) |
ABSTRACT | Methods, systems and apparatus for automated extraction, purification, and processing of nucleic acids from biological samples are presented. In some embodiments, hydrogel supports are used to immobilize particulate biological input samples and extract nucleic acids during operations. The use of hydrogel facilitates automated sample processing on robotic liquid handling systems. Devices, methods, and systems are also provided for electrophoretic sample preparation. |
FILED | Thursday, October 15, 2015 |
APPL NO | 15/519516 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) Original (OR) Class C12N 15/1017 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44747 (20130101) G01N 27/44773 (20130101) G01N 27/44782 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10136083 | Veeder |
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APPLICANT(S) | Senseeker Engineering Inc. (Goleta, California) |
ASSIGNEE(S) | Senseeker Engineering Inc. (Goleta, California) |
INVENTOR(S) | Kenton Veeder (Santa Barbara, California) |
ABSTRACT | The present disclosure provides a delta-sigma modulator circuit for use in a pixelated image sensor or a readout integrated circuit. In one aspect, the modulator circuit includes a dynamic resistance element configured to have a variable resistance that changes in accordance with a voltage difference across the dynamic resistance element. |
FILED | Monday, February 27, 2017 |
APPL NO | 15/443968 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Pictorial Communication, e.g Television H04N 5/378 (20130101) H04N 5/3577 (20130101) Original (OR) Class H04N 5/37455 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 10130671 | Arvik et al. |
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APPLICANT(S) | SONOMACEUTICALS, LLC (Santa Rosa, California); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
ASSIGNEE(S) | SONOMACEUTICALS, LLC (Santa Rosa, California); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
INVENTOR(S) | Torey James Arvik (Santa Rosa, California); Hyunsook Kim (Seoul, South Korea); Wallace H. Yokoyama (Albany, California); Scott R. Forsberg (Santa Rosa, California) |
ABSTRACT | Embodiments described herein provide for uses of grape products, such as Chardonnay grape products and grape seed flour, for use in promoting a healthy liver, promoting healthy fat content in a liver, for treating or preventing NAFLD, and other embodiments and uses as described herein. |
FILED | Friday, December 18, 2015 |
APPL NO | 15/537661 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 36/28 (20130101) A61K 36/28 (20130101) A61K 36/79 (20130101) A61K 36/79 (20130101) A61K 36/87 (20130101) Original (OR) Class A61K 36/87 (20130101) A61K 36/9066 (20130101) A61K 36/9066 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP29847 | Hemstad et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Peter Hemstad (Edina, Minnesota); Nicholas Smith (Sauk City, Wisconsin); Kathryn Cook (Montour Falls, New York); John Thull (Excelsior, Minnesota); James Luby (St. Paul, Minnesota) |
ABSTRACT | The invention is a new and distinct variety of grapevine plant named ‘Itasca’, which is characterized by its adaptibility to grow in cold climates for grape production, its cold hardiness to at least U.S.D.A. Zone 4, its fruits that are suitable for making white wine, its fruit with moderately low total acidity levels combined with high sugar levels at maturity, and its high resistance to downy mildew and black rot diseases and moderate resistance to powdery mildew and foliar infestation by the insect pest phylloxera. |
FILED | Monday, January 09, 2017 |
APPL NO | 15/530394 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/207 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 10135708 | Dinan et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | James Dinan (Hudson, Massachusetts); David Keppel (Seattle, Washington) |
ABSTRACT | Technologies for monitoring communication performance of a high performance computing (HPC) network include a performance probing engine of a source endpoint node of the HPC network. The performance probing engine is configured to generate a probe request that includes a timestamp of the probe request and transmit the probe request to a destination endpoint node of the HPC network communicatively coupled to the source endpoint node via the HPC network. The performance probing engine is additionally configured to receive a probe response from the destination endpoint node via the HPC network and to generate another timestamp that corresponds to the probe request having been received. Further, the performance probing engine is configured to determine a round-trip latency as a function of the probe request and probe response timestamps. Other embodiments are described and claimed. |
FILED | Friday, September 25, 2015 |
APPL NO | 14/866536 |
ART UNIT | 2441 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/10 (20130101) H04L 43/0876 (20130101) Original (OR) Class H04L 67/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10135711 | Zak et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Robert C. Zak (Bolton, Massachusetts); David Keppel (Mountain View, California); James Dinan (Hudson, Massachusetts) |
ABSTRACT | Technologies for tracing network performance include a network computing device configured to receive a network packet from a source endpoint node, process the received network packet, capture trace data corresponding to the network packet as it is processed by the network computing device, and transmit the received network packet to a target endpoint node. The network computing device is further configured to generate a trace data network packet that includes at least a portion of the captured trace data and transmit the trace data network packet to the destination endpoint node. The destination endpoint node is configured to monitor performance of the network by reconstructing a trace of the network packet based on the trace data of the trace data network packet. Other embodiments are described herein. |
FILED | Tuesday, December 22, 2015 |
APPL NO | 14/979140 |
ART UNIT | 2464 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/04 (20130101) H04L 43/028 (20130101) H04L 43/106 (20130101) Original (OR) Class H04L 43/0876 (20130101) H04L 45/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
US 10132614 | Froggatt et al. |
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FUNDED BY |
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APPLICANT(S) | INTUITIVE SURGICAL OPERATIONS, INC. (Sunnyvale, California) |
ASSIGNEE(S) | Intuitive Surgical Operations, Inc. (Sunnyvale, California) |
INVENTOR(S) | Mark Froggatt (Blacksburg, Virginia); Dawn K. Gifford (Blacksburg, Virginia); Stephen T. Kreger (Blacksburg, Virginia); Alexander K. Sang (Christiansburg, Virginia); Jeffrey T. Lacroix (Blacksburg, Virginia); Eric E. Sanborn (Blacksburg, Virginia) |
ABSTRACT | An optical fiber includes multiple optical waveguides configured in the fiber. An interferometric measurement system mitigates or compensates for the errors imposed by differences in a shape sensing optical fiber's response to temperature and strain. A 3-D shape and/or position are calculated from a set of distributed strain measurements acquired for a multi-core optical shape sensing fiber that compensates for these non-linear errors using one or more additional cores in the multicore fiber that react differently to temperature changes than the existing cores. |
FILED | Monday, December 07, 2015 |
APPL NO | 15/520950 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/18 (20130101) G01B 11/161 (20130101) Original (OR) Class G01B 21/042 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/344 (20130101) G01D 5/35316 (20130101) G01D 5/35354 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/242 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/3172 (20130101) G01M 11/3181 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02042 (20130101) G02B 6/02057 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10133983 | Chelian et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Suhas E. Chelian (Encino, California); Stephanie E. Goldfarb (Santa Monica, California); Rajan Bhattacharyya (Sherman Oaks, California) |
ABSTRACT | Described is system for modeling probability matching and loss sensitivity among human subjects. A set of features related to probability matching and loss sensitivity is extracted from collected human responses. The set of features are processed with a genetic algorithm to fit the collected human responses with a set of neural network model instances. A set of model parameters are generated from the genetic algorithm and used to generate at least one of an explanatory and predictive model of human behavior. |
FILED | Wednesday, April 22, 2015 |
APPL NO | 14/693485 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/126 (20130101) G06N 7/005 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 10130614 | Finegold |
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FUNDED BY |
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APPLICANT(S) | Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Sydney M. Finegold (Los Angeles, California) |
ABSTRACT | The invention provides for methods of treating autism associated with Desulfovibrio overgrowth in the gastrointestinal tract of a patient, said method comprising administering to the patient suffering from said autism a treatment course of aztreonam in an amount effective to treat autism in the patient, thereby treating autism. |
FILED | Wednesday, June 28, 2017 |
APPL NO | 15/636472 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/43 (20130101) A61K 31/397 (20130101) A61K 31/397 (20130101) A61K 31/424 (20130101) A61K 31/424 (20130101) A61K 31/427 (20130101) Original (OR) Class A61K 31/427 (20130101) A61K 31/431 (20130101) A61K 31/431 (20130101) A61K 35/741 (20130101) A61K 35/745 (20130101) A61K 35/747 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Technologies for Adaptation to Climate Change Y02A 50/473 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 10131513 | Brown et al. |
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FUNDED BY |
|
APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | John W. Brown (Manassas, Virginia); Edward F. Houston (Baristow, Virginia); Juan A. Roman (Fairfax, Virginia); Leung M. Shiu (Gaithersburg, Maryland); Riley Houston Mayhall, III (Gaithersburg, Maryland); William P. McConnell (Woodstock, Maryland); Matthew G. Good (Marriottsville, Maryland); Robert E. Hume (Granite, Maryland); Thomas A. Hillerich, Jr. (Louisville, Kentucky); Long K. Ha (Frederick, Maryland) |
ABSTRACT | Embodiments of a system and method for singulating articles in an automatic stack feeder are disclosed. The automatic stack feeder may comprise a pressure sensor on a perforated drive belt assembly configured to sense the pressure exerted by a stack of articles. The sensed pressure may be used to control various portions of the automatic stack feeder, such as a belt or a paddle. |
FILED | Friday, May 13, 2016 |
APPL NO | 15/154603 |
ART UNIT | 3652 — Material and Article Handling |
CURRENT CPC | Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 1/025 (20130101) B65H 3/124 (20130101) B65H 7/06 (20130101) Original (OR) Class B65H 2220/01 (20130101) B65H 2220/01 (20130101) B65H 2220/02 (20130101) B65H 2511/214 (20130101) B65H 2511/214 (20130101) B65H 2513/10 (20130101) B65H 2513/10 (20130101) B65H 2515/34 (20130101) B65H 2515/34 (20130101) B65H 2701/1916 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 10132628 | Golob et al. |
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FUNDED BY |
|
APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Richard Golob (Shoreline, Washington); Justin Cleve Hatcher (Seattle, Washington); Jung Soon Jang (Bellevue, Washington); Kimberly Ann Hinson (Seattle, Washington); Jeffrey L. Musgrave (Seattle, Washington) |
ABSTRACT | An aerial refueling boom elevation estimation (“ARBEE”) system for estimating an elevation angle of an aerial refueling boom on an aerial refueling aircraft is described. The ARBEE system may include a data collector, storage unit, optimizer, and comparator. |
FILED | Friday, March 06, 2015 |
APPL NO | 14/640878 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 39/00 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 9/02 (20130101) G01C 9/005 (20130101) Original (OR) Class G01C 25/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134135 | Zhang et al. |
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FUNDED BY |
|
APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Lei Zhang (Torrance, California); Kyungnam Kim (Oak Park, California); Deepak Khosla (Camarillo, California); Jiejun Xu (Chino, California) |
ABSTRACT | Described is a system for finding open space for robot exploration. During operation, the system designates a straight forward direction as a default direction. It is determined if a filtered 3D point cloud has a sufficient number of cloud points. If not, the system determines if an obstacle is too close in a previous time. If so, a backward direction is set as a target direction and if not, the straight forward direction is set as the target direction. Alternatively, if there are a sufficient number of points, then calculate a distance of each point to a sensor center and determine if a number of times that the distance is smaller than a distance threshold is greater than a fixed number. The system either sets the backward direction as the target direction or estimates an openness of each candidate direction until a candidate direction is set as the target direction. |
FILED | Monday, August 29, 2016 |
APPL NO | 15/249655 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0042 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2207/20024 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/19 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 10134501 | Hunter et al. |
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FUNDED BY |
|
APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Ian W. Hunter (Lincoln, Massachusetts); Lauren Montemayor (San Antonio, Texas); Eli Travis Paster (Cambridge, Massachusetts); Priam Pillai (Pleasant Hill, California) |
ABSTRACT | Method for connecting two portions of a first electrically conducting polymer with a second polymer. The method includes disposing a solution of a second polymer in a solvent to be in contact with the two portions of the first electrically conducting polymer and allowing the solvent to evaporate leaving the second polymer joining the two portions of the first polymer. The second polymer may be doped to improve its conductivity. |
FILED | Wednesday, February 13, 2013 |
APPL NO | 13/766257 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/12 (20130101) H01B 1/127 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 20, 2018.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2018/fedinvent-patents-20181120.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page